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See detailSuccessful removal of an intramedullary spinal paraganglioma from a dog
Poncelet, Luc; Snaps, Frédéric ULg; Jacobovitz, D. et al

in Journal of the American Animal Hospital Association (1994), 30(3), 213-216

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was ... [more ▼]

An 11-year-old, mixed-breed dog suffering progressive asymmetric hind limb ataxia was diagnosed as having spinal cord compression at the L1 spinal level. An intramedullary, encapsulated tumor was surgically removed. Tumor microscopic features, positive neuron-specific enolase (NSE) immunostaining, and Grimelius staining led to the diagnosis of paraganglioma. The dog was free from any neuroloaic signs 12 days after surgery. [less ▲]

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See detailDe l'utopie en architecture
Tieleman, David ULg

in A+ (1994)

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See detailTranscription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitum beta-lactamase genes cloned from a natural isolate and a high-level beta-lactamase producer.
Timm, J; Perilli, M G; Duez, Colette ULg et al

in Molecular Microbiology (1994), 12(3), 491-504

The gene encoding a class A beta-lactamase was cloned from a natural isolate of Mycobacterium fortuitum (blaF) and from a high-level amoxicillin-resistant mutant that produces large amounts of beta ... [more ▼]

The gene encoding a class A beta-lactamase was cloned from a natural isolate of Mycobacterium fortuitum (blaF) and from a high-level amoxicillin-resistant mutant that produces large amounts of beta-lactamase (blaF*). The nucleotide sequences of the two genes differ at 11 positions, including two in the region upstream from the coding sequence. Gene fusions to Escherichia coli lacZ and transcription and expression analysis of the cloned genes in Mycobacterium smegmatis indicated that high-level production of the beta-lactamase in the mutant is mainly or wholly due to a single base pair difference in the promoter. These analyses also showed that transcription and translation start at the same position. A comparison of the amino acid sequence of BlaF, as predicted from the nucleotide sequence, with the determined N-terminal amino acid sequence indicated the presence of a typical signal peptide. The fusion of blaF (or blaF*) to the E. coli gene phoA resulted in the production of BlaF-PhoA hybrid proteins that had alkaline phosphatase activity. These results demonstrate that phoA can be used as a reporter gene for studying protein export in mycobacteria. [less ▲]

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See detailLes disparités et les dynamiques territoriales. Introduction méthodologique
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (1994), (30), 5-14

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory ... [more ▼]

This paper considers three kinds of methodological problems in the field of territorial dynamics and disparities. First of all, the definition of the concepts of disparity, dynamics and territory; secondly, the choice of spatial analysis levels, temporal limits and indicators and finally research into explanations. These are always very complicated and pratical despite the contribution of the major regional development theories and the new inquiries of regional science in the field of perceptions, networks and actors' roll. [less ▲]

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See detailL'inventaire forestier régional wallon: brève présentation méthodologique.
Lecomte, H.; Rondeux, Jacques ULg

in Silva Belgica (1994), 101(6), 9-16

Au début des années 1980, à l’initiative de la Faculté des Sciences agronomiques de Gembloux et grâce à un financement de la Région Wallonne, un inventaire a été réalisé sur l’ensemble de la Wallonie ... [more ▼]

Au début des années 1980, à l’initiative de la Faculté des Sciences agronomiques de Gembloux et grâce à un financement de la Région Wallonne, un inventaire a été réalisé sur l’ensemble de la Wallonie [RONDEUX et al., 1984]. Cet inventaire s’appuyant sur un échantillonnage systématique simple était destiné à fournir un état des lieux de la forêt wallonne de l’époque ; il a notamment permis de confirmer ou de mettre en évidence plusieurs éléments essentiels pour l’avenir du patrimoine forestier wallon [RONDEUX et al., 1986] : - le vieillissement de la hêtraie ardennaise ; - l’importante disponibilité en bois d’épicéa ; - les écarts entre les surfaces forestières observées et celles du recensement officiel. Depuis la fin de cet inventaire en 1984, aucune mise à jour n’a été programmée et en conséquence, ses résultats ont perdu leur fiabilité notamment en raison des accidents météorologiques de la dernière décennie. En 1988, l’Exécutif de la Région Wallonne, conscient de l’importance de la forêt en tant que première ressource naturelle renouvelable de la Wallonie, a sollicité la Faculté des Sciences agronomiques de Gembloux en vue de finaliser une recherche destinée à concevoir une méthodologie d’inventaire forestier permanent. Les conclusions de cette étude ont été déposées fin 1993 [LECOMTE, 1994], ce qui a permis de lancer dès février 1994 la phase opérationnelle du premier inventaire forestier permanent pour la Wallonie. Dans les lignes qui suivent, nous aborderons successivement les objectifs de l’inventaire (paragraphe 2) ainsi que les principes généraux qui le régissent (paragraphe 3). Le cheminement de l’information sera décrit depuis la récolte des données (paragraphe 4) jusqu’à la publication des résultats (paragraphe 7) en passant par le traitement et l’exploitation des données (paragraphes 5 et 6). En guise de conclusions, nous émettrons quelques réflexions issues de notre propre expérience (paragraphe 8). [less ▲]

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See detailThiamine in Excitable Tissues: Reflections on a Non-Cofactor Role
Bettendorff, Lucien ULg

in Metabolic Brain Disease (1994), 9(3), 183-209

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See detailAnticorps anticytoplasme des polynucléaires neutrophiles (ANCA) dans les maladies inflammatoires du tube digestif
Lamproye, Anne ULg; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1994), 57(2, Mar-Apr), 171-6

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and ... [more ▼]

Antineutrophil cytoplasmic antibodies have recently been demonstrated in sera of patients with inflammatory bowel disease. We are reporting here our experience among 94 patients with Crohn's disease and 25 with ulcerative colitis. The indirect immunofluorescence assay with alcohol fixed neutrophils has been used. The presence of antineutrophil cytoplasmic antibodies was significantly associated to the ulcerative colitis 61% VS 17% (p < 0.001). The fluorescence had a perinuclear pattern among all but one suffering from ulcerative colitis. Among the patients suffering from ulcerative colitis there was no relationship between the presence of antineutrophil cytoplasmic antibodies and the activity or the localisation of the disease. Among the 9 patients operated for their ulcerative colitis, 4 were ANCA positive and remained so after proctocolectomy. The existence of antineutrophil cytoplasmic antibodies is useful for the diagnosis of some unclassifiable colitis. Their presence may be used as an argument in favour of some disturbances of the immunoregulation of the disease. [less ▲]

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See detailA new species of trametes from Papua New Guinea
Castillo Cabello, Gabriel ULg

in Mycotaxon (1994)

Trametes demoulinii from Papua New guinea is descrebed as new. The new taxon is closest to Trametes conchifer and Trametes membranacea, both from America and Trametes cingulata know in Africa and East ... [more ▼]

Trametes demoulinii from Papua New guinea is descrebed as new. The new taxon is closest to Trametes conchifer and Trametes membranacea, both from America and Trametes cingulata know in Africa and East Asia. In addition to basidiomata, cultural characters of the new species are described. [less ▲]

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See detailUtilisation des moules comme bioindicateurs de la pollution en métaux lourds du littoral belge
Gobert, Sylvie ULg; Langer, Alain; Daemers-Lambert, Claire et al

in Bulletin de la Société Royale des Sciences de Liège (1994), 63(1-2), 203-210

From 1991 till 1993, a study of the Belgian coast pollution by heavy metals using Mytilus edulis as a bioindicator was performed. The Pb, Cr, Cu and Ti concentrations decreased from 1987 till 1991 but ... [more ▼]

From 1991 till 1993, a study of the Belgian coast pollution by heavy metals using Mytilus edulis as a bioindicator was performed. The Pb, Cr, Cu and Ti concentrations decreased from 1987 till 1991 but then remained unchanged till 1993. Cd contamination is increasing from 1987. Hg, whose concentration had been shown to decrease from 1975 to 1991, now reaches the same values as in 1986. The O/N measurements performed on the mussels suggest an increase of the general pollution level of the Belgian coast. However, feeding, spawning and detoxification processes are also able to influence the O/N ratio and should be taken into account in the framework of a global assessment of the pollution level of the Belgian coast [less ▲]

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See detailCo-movements and dynamic interrelationships in pacific basin stock markets
Corhay, Albert ULg; Tourani-Rad, Alireza; Urbain, Jean-Pierre ULg

in Research in International Business and Finance (1994), 11B

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we ... [more ▼]

In this paper, we investigate dynamic interrelationships among the stock markets of Australia, Hong Kong, Japan, New Zealand and Singapore. Using cointegration analysis and the Granger causality test we find that, although the five stock price indices share some common trends, the only stock price which does not apparently Granger cause (precede) the remaining stock prices is that of New Zealand. It is further observed that all price indices are caused by the remaining stock prices except that of Australia. With respect to the geographical separation, it appears that when we consider the Asian countries as an entity and those of the Pacific as another entity, they seem not to influence each other significantly. [less ▲]

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See detailLes méthodes d'analyse factorielle : principes et applications
Palm, Rodolphe ULg

in Biométrie-Praximétrie (1994), 34

This note describes in a simple way the principles of the factorial methods, and more particularly of the principal component anlaysis and the correspondence analysis. The emphasis is put on the elements ... [more ▼]

This note describes in a simple way the principles of the factorial methods, and more particularly of the principal component anlaysis and the correspondence analysis. The emphasis is put on the elements useful when interpreting the results of an analysis and the methods are illustrated by completely worked out examples. [less ▲]

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See detailFactors influencing between-laboratory variability of C-reactive protein results as evidenced by the Belgian External Quality Assessement (EQA) Scheme
Devleeschouwer, N.; Libeer, J. C.; Chapelle, Jean-Paul ULg et al

in Scandinavian Journal of Clinical & Laboratory Investigation (1994), 54(6), 435-40

Based on results from the Belgian External Quality Assessment (EQA) Scheme, we studied the main factors affecting the between-laboratory variation of C-reactive protein determination. Participants using ... [more ▼]

Based on results from the Belgian External Quality Assessment (EQA) Scheme, we studied the main factors affecting the between-laboratory variation of C-reactive protein determination. Participants using homogeneous systems with several calibration points generally achieved better performance. Working temperatures influenced the results to a lesser extent. The present study stresses the importance for EQA organizers to collect more detailed information about CRP analytical methods used by the participants. It also suggests that manufacturers should be more involved in the management of quality, in particular by striving for standardization of the material (kit and calibrator) they produce for CRP assay. [less ▲]

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See detailDie Devon/Karbongrenze bei Stockum (Rheinisches Schiefergebirge).
Clausen, C.D.; Korn, D; Feist, R et al

in Geologie und Paläontologie in Westfalen (1994), 29

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See detailPassive immunization against insulin-like growth factor-I alters the placental lactogen concentration in pregnant rats
Devolder, Anne; Renaville, Robert ULg; Massart, Serge et al

in Journal of Animal Science (1994), 72(suppl 1), 159

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See detailSyndrome naviculaire : anatomie, étio-pathogénie, diagnostic et traitement
Gabriel, Annick ULg; Caudron, I.; Serteyn, Didier ULg et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailINTERNATIONAL-CONFERENCE ON BARBUS - PRESENT AND FUTURE - FOREWORD
BERREBI, P.; Poncin, Pascal ULg

in Bulletin Francais De La Peche Et De La Pisciculture (1994), (334), 167-168

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See detailCONTINUOUS ENZYMATIC-SYNTHESIS OF 2'-DEOXYTHYMIDINE-5'(ALPHA-D-GLUCOPYRANOSYL)DIPHOSPHATE
Zervosen, Astrid ULg; ELLING, Lothar; KULA, Maria-Regina

in Angewandte Chemie (International ed. in English) (1994), 33(5), 571-572

The preparation of primary nucleotide sugars like dTDP-glucose with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific ... [more ▼]

The preparation of primary nucleotide sugars like dTDP-glucose with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific pyrophosphorylases. In an enzyme membrane reactor a continuous synthesis can be performed on preparative scale. [less ▲]

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See detailLes Formations du Dévonien inférieur du Massif de la Vesdre, de la Fenêtre de Theux et du Synclinorium de Dinant (Belgique, France)
Godefroid, J; Blieck, A; Bultynck, P et al

in Memoirs of the Geological Survey of Belgium (1994), 38

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See detailGéologie de la région de Puagne, Bande de Sambre-et-Meuse (Belgique). Hypothèses basées sur l'état de maturation des palynomorphes fossiles
Steemans, Philippe ULg

in Comptes Rendus de l'Académie des Sciences. Série 2, Sciences de la Terre et des Planètes (1994), 318(11), 1551-1556

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See detailTamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype
Bracke, M. E.; Charlier, Corinne ULg; Bruyneel, E. A. et al

in Cancer Research (1994), 54

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See detailObservations on the establishment of a Devonian and Lower Carboniferous high resolution miospore biostratigraphy
Streel, Maurice ULg; Loboziak, S

in Review of Palaeobotany and Palynology (1994), 83

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See detailBiostatistical studies of Western European allogamous populations of the Epipactis helleborine (L.) Crantz species group (Orchidaceae)
Tyteca, D.; Dufrêne, Marc ULg

in Systematic Botany (1994), 19(3), 424-442

[No abstract available]

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See detailMBO en Aandeelhouder
Corhay, Albert ULg; Herst, Arthur; Tourani Rad, Alireza

in Bedrifskunde (1994), 4

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See detailApprendre, ou se mettre en projet ? Réflexions au départ d'une expérience de pédagogie du projet en classe du secondaire
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1994), 44e année(n°1), 5-17

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See detailModification of immunoreactive EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin
Leonard, I.; Zanen, J.; Nonclercq, D. et al

in Renal Failure (1994), 16(5), 583-608

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of ... [more ▼]

Acute tubular necrosis induced by aminoglycoside antibiotics and various other nephrotoxins is followed by a regenerative process which leads to the restoration of damaged tubules. Several lines of evidence indicate that tubular regeneration is mediated by polypeptide growth factors such as epidermal growth factor (EGF). Previous studies devoted to cisplatin nephrotoxicity have shown that this agent causes tubular cystic degeneration possibly related to an impairment of renal tissue repair. Thus, we examined on a comparative basis the time course of the regenerative response subsequent to tubular damage induced by tobramycin or cisplatin, particular attention being paid to renal EGF and its receptor. Female Sprague-Dawley rats (160-180 g body weight) were treated during 4 consecutive days with daily doses of 200 mg/kg tobramycin i.p. (BID) or 2 mg/kg cisplatin (once a day). Sham-treated rats were given 0.9% NaCl i.p. following the same protocol. Groups of experimental animals (n = 5-10) were terminated at increasing time intervals (1, 4, 7, 14, 21, 60 days) after cessation of treatment. One hour prior to sacrifice, each individual received i.p. 200 mg/kg 5-bromo-2'-deoxyuridine (BrdU) for the immunohistochemical demonstration of cell proliferation. Blood was collected at the time of sacrifice in order to assess glomerular filtration rate by measuring serum creatinine and BUN levels. Kidneys were analyzed with respect to total EGF determined by RIA in renal tissue homogenates, and soluble EGF was assayed in extracts prepared by centrifugation. Renal tissue was processed for the immunohistochemical detection of S-phase cells, of EGF, of EGF receptors, and of the intermediate filament vimentin, the latter being used as a marker of epithelium dedifferentiation. In absence of nephrotoxic alterations, EGF was immunolocalized in distal tubules, whereas EGF receptor immunostaining was seen in proximal tubules cells. Vimentin immunostaining was confined to glomeruli and blood vessels. Tobramycin and cisplatin caused acute tubular necrosis in proximal convoluted tubules and proximal straight tubules, respectively. Tissue damage was accompanied by renal dysfunction reflected by an elevation of serum creatinine and BUN levels. Tubular necrosis was followed by a proliferative response indicative of tubular regeneration. Regenerative hyperplasia was associated with a reduction of total immunoreactive EGF due to a decrease of tissue-bound proEGF. Tubules undergoing regenerative repair were characterized by a disappearance of EGF receptors and the presence of immunoreactive vimentin. In tobramycin-treated rats, renal dysfunction lasted for 4-7 days and was fully reversible, as indicated by the return of serum markers to normal values. [less ▲]

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See detailExpression of intron-encoded maturase-like polypeptides in potato chloroplasts.
du Jardin, Patrick ULg; Portetelle, Daniel ULg; Harvengt, Luc et al

in Current Genetics (1994), 25(2), 158-163

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See detailReaction Dynamics of Collisionally activated Ammonia Cations.
Leyh, Bernard ULg; Hoxha, A.

in Chemical Physics (1994), 179

In the framework of a research on the collisional mechanisms involved in tandem mass spectrometry, the collisional activation processes of NH3+ with different target gases have been investigated. The ... [more ▼]

In the framework of a research on the collisional mechanisms involved in tandem mass spectrometry, the collisional activation processes of NH3+ with different target gases have been investigated. The experiments have been performed on an upgraded AEI-MS9 sector instrument equipped with two collision cells and include daughter ion spectra, ion kinetic energy spectra, determination of kinetic energy release distributions (KERD) and appearance energy measurements. We have shown that collisionally activated dissociation (CAD) of NH3+ into NH++[H,H] depends upon the internal energy of NH3+. This internal energy effect is also observed for the NH2++H channel, when Xe is the target gas; with He, such an effect could not be detected. The analysis of the KERD shows that production of NH2+ upon CAD takes place from the NH3+ ground electronic state by rotational predissociation; two components are observed, one which corresponds to a near-threshold process (mean kinetic energy release <T>=0.13 eV), and one characterized by <T>=0.56 ev corresponding to an excess energy of 2.1 eV above the dissociation threshold. NH+ fragments can be formed by two processes: the first one occurs at threshold and leads to NH+(X2Pi)+H2(X1Sigma+g); the second one is characterized by large KER values (up to 7 eV) and leads to either electronically excited NH+ or dissociation of H2. [less ▲]

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See detailCritical appraisal of pressure-frequency relation for estimation of diaphragm function in intact and conscious animals
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in American Journal of Veterinary Research (1994), 55(12), 1638-1646

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See detailAcute biochemical variations induced by four different calcium salts in healthy male volunteers
Reginster, Jean-Yves ULg; Denis, D; Bartsch, V et al

in Equilibre (1994), 19

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See detailANOMALOUS PERTURBATIVE TRANSPORT IN TOKAMAKS DUE TO DRIFT-WAVE TURBULENCE
Thoul, Anne ULg; SIMILON, P. L.; SUDAN, R. N.

in Physics of Plasmas (1994), 1(3), 579-600

A new method for calculating the anomalous transport in tokamak plasmas is presented. The renormalized nonlinear plasma response function is derived using the direct-interaction approximation (DIA). A ... [more ▼]

A new method for calculating the anomalous transport in tokamak plasmas is presented. The renormalized nonlinear plasma response function is derived using the direct-interaction approximation (DIA). A complete calculation for the case of electrostatic drift-wave turbulence is presented. Explicit expressions for all coefficients of the anomalous transport matrix relating particle and heat fluxes to density and temperature gradients in the plasma are obtained. The anomalous transport matrix calculated using the DIA does not have the Onsager symmetry. As an example of application, the parameters of the Texas Experimental Tokamak (TEXT) [Nucl. Technol. Fusion 1, 479 (1981)] are used to evaluate all transport coefficients numerically, as well as the spectrum modulation. The relation between the theoretical results and the experimental data is discussed. Although this paper focuses on electron transport for simplicity, the method can also be used to calculate anomalous transport due to ion instabilities, such as the ion-temperature-gradient instability. [less ▲]

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See detailEvaluation of Matrix Metalloproteinases and Serine Proteases Activities in Three B16 Melanoma Cell Lines with Distinct Tumorigenic Potential
Baramova, E. N.; Coucke, P.; Leprince, Pierre ULg et al

in Anticancer Research (1994), 14(3A, May-Jun), 841-6

Mouse B16 melanoma cells (B16, parental line) and two derived clones either pigmented (B16P) or non pigmented (B16NP) were cultured as monolayers (2D) or on agar, as aggregates (3D). The productions of ... [more ▼]

Mouse B16 melanoma cells (B16, parental line) and two derived clones either pigmented (B16P) or non pigmented (B16NP) were cultured as monolayers (2D) or on agar, as aggregates (3D). The productions of gelatinases A and B (72 kDa and 92 kDa type IV collagenases) and their inhibitors (TIMP1 and TIMP2), plasminogen activators (PAs) and plasminogen activator inhibitors (PAI) were investigated. The B16 cell lines did not secrete any gelatinase, but they secreted TIMP2, tissue-type (t-PA), urokinase-type (u-PA) plasminogen activators and PAI-1 like activities. High levels of PAI activity were determined in conditioned media and cellular extracts of B16NP, which could account for the lower tumorigenic potential of these cells. In 3D cultures, the cellular extracts of the three cell lines contained essentially u-PA activity. This activity could contribute to the greater tumorigenic and invasive capacities of B16, B16P and B16NP when cultured in 3D. [less ▲]

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See detailDémographie du martin pêcheur (Alcedo atthis): incidences climatiques sur le succès reproducteur
Libois, Roland ULg

in Gerfaut (Le) = Giervalk (De) (1994), 84

It is well known that the Kingfisher populations decrease dramatically after a sever winter. The recovery depends on the climatic conditions of the next reproductive seasons. In order to understand the ... [more ▼]

It is well known that the Kingfisher populations decrease dramatically after a sever winter. The recovery depends on the climatic conditions of the next reproductive seasons. In order to understand the mechanism involved in this climatic influence, the fate of more than 500 broods was studied between 1985 and 1993. The study area comprises the river Meuse from Vireux (F,08) downstreams to Huy (B Liège) and the lower part of its main tributaries. The first egg laying date was determined for each brood, eggs were counted, pulli ringed at nest and the adults controlled and ringed when possible. Our main conclusions are i : the beginning of the first clutch is correlated with the thermic conditions of March. ii : the clutches are not synchronised, even on a same watercourse. iii : the egg probuction and the hatching success don't show clear variations between years abd habitat types (river, ponds and small streams) or depending on the clutch rank. iv : the fledged young production depends on how much broods are raised by the different pairs. v : the probability a pair is attempting a thrid brood is function of how early the first clutch is layed, the age of the male (older males settle earlier and are more productive), the habitat quality and the weather conditions (rain, temperature) in May. [less ▲]

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See detailCardio-respiratory, haematological and biochemical parameter adjustments to exercise: effect of a probiotic in horses during training
Art, Tatiana ULg; Votion, Dominique ULg; Mc Entee, Kathleen ULg et al

in Veterinary Research (1994), 25(4), 361-370

Two randomly distributed groups of thoroughbred horses were compared during a 12-week period for their cardio-respiratory and metabolic adjustment to strenuous exercise, training and detraining. The ... [more ▼]

Two randomly distributed groups of thoroughbred horses were compared during a 12-week period for their cardio-respiratory and metabolic adjustment to strenuous exercise, training and detraining. The horses were trained following the same standardized schedule and were regularly investigated using standardized treadmill exercise tests (SET) of increasing speed. After the first SET and during the whole experimental period, a group of 6 horses received a probiotic (Bioracing) once a day while a group of 5 horses received a placebo. All other conditions were similar for both groups. During each SET, the oxygen uptake, carbon dioxide output, tidal volume (inspired volume), respiratory rate and expired minute volume were obtained using 2 ultrasonic pneumotachographs and a mass spectrometer. All the parameters were the mean of the values calculated during the last 20 s of the SET. Heart rate was continuously measured with a polar horse tester. Venous blood was sampled before and after the test and analyzed for various biochemical parameters. In both groups, training induced significant modification in most of the cardio-respiratory parameters, ie peak oxygen uptake, peak carbon dioxide output, respiratory exchange ratio, ventilation/min to oxygen-uptake ratio and oxygen-uptake to heart-rate ratio. After the 3-week detraining period, most of the values were again similar to the pre-training values in both groups. However, the training-induced modifications of most of the cardio-respiratory parameters occurred earlier and were proportionally greater in the probiotic-treated group than in the control. The respiratory coefficient decreased in the control but not in the treated group. All other parameters changed similarly in both groups. This suggests that Bioracing could modify the physiological effects of training by improving some aerobic metabolic capacities for carbohydrate utilization, but that this effect occurs only during training and not during periods of physical inactivity [less ▲]

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See detailTaqi Restriction-Fragment-Length-Polymorphisms For Growth-Hormone In Bovine Breeds And Their Association With Quantitative Traits
Sneyers, M.; Renaville, Robert ULg; Falaki, M. et al

in Growth Regulation (1994), 4(3),

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See detailLa régression : un problème statistique complexe à partir d'une idée simple
Palm, Rodolphe ULg

in Biométrie-Praximétrie (1994), 34(2), 109-123

Comme beaucoup de domaines de la statistique, la régression a connu d'importants développements au cours de ces vingt-cinq dernières années et l'objectif de l'article est de présenter, de façon sommaire ... [more ▼]

Comme beaucoup de domaines de la statistique, la régression a connu d'importants développements au cours de ces vingt-cinq dernières années et l'objectif de l'article est de présenter, de façon sommaire, les développements relatifs à quelques aspects particuliers de la régression linéaire, même si certains éléments peuvent être facilement étendus ou adpatés au cas de la régression non linéaire. Nous examinerons tout d'abord le problème de la validation des résultats d'une régression, en considérant successivement les critères globaux de mesure de la qualité de la régression, la division des données et la validation croisée, les représentations graphiques et les mesures de l'influence. Ensuite, nous envisagerons l'établissement des équations de régression, en abordant le problème du choix des variables et en évoquant quelques alternatives à la régression classique, en relation, notamment, avec la colinéarité. Enfin, nous terminerons par quelques conclusions. [less ▲]

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See detailFate of unstimulated Latissimus Dorsi transposed into the chest and applied to cardiomyoplasty
Radermecker, M. A.; Reznik, M.; Vivario, M. et al

in Research in Surgery (1994), 6(1), 35-39

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See detailHereditary muscular hypertrophy in cattle is associated with a reduced myocardial contractility
Amory, Hélène ULg; Mc Entee, Kathleen ULg; Linden, Annick ULg et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailLes choix stratégiques actuels dans la prévention du processus diabétogène auto-immun
Geenen, Vincent ULg; Martens, Henri ULg; Kecha, Ouafae et al

in Médecine et Hygiène (1994), 52

Le diabète insulino-dépendant (DID) est de plus en plus admis comme résultant d'une rupture de la tolérance immunitaire vis-à-vis de la cellule ß pancréatique. La compréhension des mécanismes centraux et ... [more ▼]

Le diabète insulino-dépendant (DID) est de plus en plus admis comme résultant d'une rupture de la tolérance immunitaire vis-à-vis de la cellule ß pancréatique. La compréhension des mécanismes centraux et périphériques de la tolérance vis-à-vis de la cellule ß doit logiquement aboutir à une prévention non toxique et efficace du DID. Deux choix stratégiques sont proposés à l'heure actuelle. D'une part, la tolérance périphérique à l'insuline en tant que cible du processus auto-immun pourrait être restaurée via l'administration d'insuline à faibles doses par voie sous-cutanée ou orale. D'autre part, le facteur de croissance apparenté à l'insuline de type 2 (IGF2) pourrait réinduire la tolérance centrale de l'insuline et, secondairement, de la cellule ß insulino-sécrétrice. [less ▲]

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See detailIntensities of the doublet-quadruplet intersystem transitions in C II and N III
Biémont, Emile ULg; Delahaye, F.; Zeippen, C. J.

in Journal of Physics : B Atomic Molecular & Optical Physics (1994), 27

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See detailValeur semeiologique des examens de laboratoire: application multicentrique au depistage des metastases hepatiques.
Bourguignat, Alain; Albert, Adelin ULg; Dumont, Gilles et al

in Annales de Biologie Clinique (1994), 52(11), 787-97

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See detailRestriction fragment length polymorphisms in cattle
Falaki, Mohammed; Renaville, Robert ULg; Sneyers, Myriam et al

in Journal of Animal Science (1994), 72(suppl 1), 316

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See detailDifferential diagnosis of Alzheimer's disease with PET.
Salmon, Eric ULg; Sadzot, Bernard ULg; Maquet, Pierre ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1994), 35(3), 391-8

PET studies have demonstrated bilateral temporo-parietal hypoperfusion and hypometabolism in probable and definite Alzheimer's disease (AD), a pattern that may help differentiate AD from other dementias ... [more ▼]

PET studies have demonstrated bilateral temporo-parietal hypoperfusion and hypometabolism in probable and definite Alzheimer's disease (AD), a pattern that may help differentiate AD from other dementias. METHODS: To evaluate the diagnostic power of cerebral metabolic distribution patterns for "cortical" degenerative dementias, PET scans obtained from 129 patients referred for differential diagnosis of dementia were analyzed visually. RESULTS: Sixty-five patients had a final clinical diagnosis of probable AD. Ninety-seven percent (97%) of those had abnormal metabolic scans and 94% showed a suggestive pattern of bilateral or unilateral temporo-parietal hypometabolism (with or without frontal involvement). Hypometabolism was unilateral in 23% of patients. Five subjects with a neuropathologically proven diagnosis of Alzheimer's disease had a suggestive metabolic pattern. One of those was an early case with frontal hypometabolism exceeding temporo-parietal involvement. Two patients with Alzheimer's-type dementia had isolated bilateral frontal hypometabolism. CONCLUSIONS: This alternative metabolic pattern may correspond to a non-Alzheimer pathology occurring in 10%-20% of patients suffering from clinically probable Alzheimer's disease. Most of the patients with possible but atypical Alzheimer's-type dementia showed isolated bilateral frontal involvement. This metabolic pattern probably corresponds to different diseases, such as Pick's disease, frontal lobe dementia or progressive subcortical gliosis. [less ▲]

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See detailAcute myocardial infarction in a young female migraineur: sumatriptan suspected, but found not guilty.
Schoenen, Jean ULg; Delree, P.; Moonen, Gustave ULg

in Cephalalgia : An International Journal of Headache (1994), 14(4), 305

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See detailThe structures and catalytic mechanisms of active-site serine beta-lactamases.
Lamotte, Josette ULg; Knox, J.; Kelly, J. A. et al

in Biotechnology & Genetic Engineering Reviews (1994), 12

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See detailLa gynécologie dans les papyrus grecs de médecine
Marganne, Marie-Hélène ULg

in Acta Belgica Historiae Medicinae (1994), 7(4), 207-217

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See detailMachine learning, neural networks and statistical pattern recognition for voltage security: a comparative study
Wehenkel, Louis ULg; Van Cutsem, Thierry ULg; Pavella, Mania ULg et al

in International Journal of Intelligent Systems (1994), 2

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See detailTopographic forcing of the circulation of LIW in the Western Mediterranean
Alvarez, A.; Tintoré, J.; Holloway, G. et al

in Coastal Estuarine Studies (1994), 46

Circulation of the Western Mediterranean has been inferred from tracer properties and is the object of numerical modelling studies (eg., Beckers, 1991). The path of the Levantine Intermediate Water (LIW ... [more ▼]

Circulation of the Western Mediterranean has been inferred from tracer properties and is the object of numerical modelling studies (eg., Beckers, 1991). The path of the Levantine Intermediate Water (LIW), thought o be a buoyancy forced flow, provides an indicator of mid-depth circulation (Millot, 1987b). However, modelling studies which include buoyancy forcing appear to misrepresent the flow of LIW. We have used the 'GFDL Modular Ocean Model' (MOM) to explore the suggestion of Holloway (1992) that subgridscale eddy-topography interaction may be responsible for such systematic defects. We have executed MOM with and without the parametrization of the eddytopography interaction. The different results are compared with circulation inferred from observational data. [less ▲]

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See detailDe l'utopie en architecture. Une technique pour le Corbusier ?
Tieleman, David ULg

in Art&Fact (1994), 13

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See detailPuissance maximale aérobie d’enfants en âge d’école primaire participant ou non à une leçon quotidienne d’activités physiques
Ledent, Maryse; Delfosse, Catherine; Cloes, Marc ULg et al

in Revue de l'Education Physique (1994), 34(2-3), 69-75

Plusieurs études indiquent que, chez l'adulte, il existe une relation significative entre la pratique d'activités physiques et sportives et la diminution des facteurs de risque, surtout cardiovasculaire ... [more ▼]

Plusieurs études indiquent que, chez l'adulte, il existe une relation significative entre la pratique d'activités physiques et sportives et la diminution des facteurs de risque, surtout cardiovasculaire. En particulier, l'endurance qui découle d'une pratique régulière d'activités modérés à intenses de répercute sur la condition du système cardiovasculaire et réduit significativement les risques de troubles cardiaques. ... [less ▲]

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See detailThymus Involvement in Murine Acquired Immunodeficiency (Maids)
Colombi, Sonia; Deprez, Manuel ULg; de Leval, Laurence ULg et al

in Thymus (1994), 23(1), 27-37

Due to self-renewal of the peripheral pool of T-cells, adult thymectomy has normally little influence on immunocompetence. However, thymus might play a more important role in the setting of viral-induced ... [more ▼]

Due to self-renewal of the peripheral pool of T-cells, adult thymectomy has normally little influence on immunocompetence. However, thymus might play a more important role in the setting of viral-induced cytopathic effects on T-cells in the periphery. Therefore, thymus weight, cell numbers, and subset distribution were sequentially analysed after infection with RadLV-Rs, a viral mixture known to induce murine retrovirus induced immunodeficiency (MAIDS). Infection induced thymic atrophy (concerning organ weight as well as total cell number) which culminated seven weeks after inoculation. The atrophic process mostly reflected the depletion of double positive CD4+ CD8+ cells since their proportion sharply decreased around week 6. Single positive T-cells were less affected by the process. The proportion of B-cells progressively increased. Surprisingly, there was a strong correlation between the extent of atrophy and the frequency of B-cells in the thymus. Finally, an abnormal CD4+ T-cell subset lacking Thy-1 and previously described in the periphery also appeared in the thymus and its frequency was strongly correlated with the expansion of B-cells in this organ. [less ▲]

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See detailMechanical Flow Obstruction after Heart Transplantation Diagnosed by Tee
CANIVET, Jean-Luc ULg; DEFRAIGNE, Jean ULg; Demoulin, Jean-Claude et al

in Annals of Thoracic Surgery (1994), 58(3), 890-1

We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal ... [more ▼]

We report a case of mechanical flow obstruction after heart transplantation caused by a prominent left atrium suture with a "pursestring" effect. The diagnosis was achieved by transesophageal echocardiography. The mean transstenotic gradient was measured at 13 mm Hg. Because of the profound hemodynamic and multisystemic failure, no surgical correction was attempted. The postmortem examination confirmed the stenosis at the level of the left atrium. [less ▲]

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See detailCharacterization and Tumorigenicity of Spheroids Composed of Pigmented or Non Pigmented B16 Melanoma Cells
Coucke, P. H.; Gillet, Marie-Claire ULg; Bonjean, K. A. et al

in In Vivo (Athens, Greece) (1994), 8(3, May-Jun), 333-8

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells ... [more ▼]

A parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either pigmented (B16P) or non pigmented (B16NP), were cultured in vitro as spheroids. After 48 hrs, the pigmented cells (B16, B16P) formed smaller and looser aggregates, with higher rates of cell proliferation and lower amounts of extracellular matrix as compared to B16NP spheroids. The three lines were more tumorigenic when inoculated subcutaneously as spheroids than as isolated cells. Furthermore, B16P or B16 spheroids developed richly vascularized subcutaneous tumors and metastases more rapidly than B16NP aggregates. After intravenous injection of spheroids, the measurement with an image analyzer of the area of sections in lung colonies indicated that B16P colonies were larger and more numerous than those induced by B16NP cells. [less ▲]

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See detailA screening technique to isolate bacterial strains producing high molecular weight bacteriocins
Jabrane, A.; Destain, Jean-Pierre ULg; Compère, Philippe ULg et al

in Biotechnology Techniques (1994), 8(10), 751-754

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See detailBrucellose enzootique à Brucella suis biotype 2 chez le sanglier (sus scrofa) en Belgique
Godfroid, J.; Michel, P.; Uytterhaegen, L. et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailChoix d'une nouvelle variete pour les zones cotonnieres meridionales du Zaire. Resultats des essais varietaux preliminaires.
Mergeai, Guy ULg; Ndungo, V.; Folo, A. et al

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(4),

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See detailMarqueurs tumoraux
Charlier, Corinne ULg; Plomteux, Guy ULg

in Focus Diagnostica (1994), 2

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See detailHereditary muscular hypertrophy in cattle is associated with a reduced myocardial contractility
AMORY, H; ENTEE, K Mc; LINDEN, AS et al

in Pflügers Archiv : European Journal of Physiology (1994), 426

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See detailEffect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons.
Seutin, Vincent ULg; Johnson, S. W.; North, R. A.

in Neuroscience (1994), 58(1), 201-6

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the ... [more ▼]

Intracellular microelectrode recordings were made from dopamine-containing neurons of the ventral tegmental area or substantia nigra zona compacta in rat brain slices in vitro. The firing pattern of the neurons was switched from a tonic, single-spike pattern to a burst firing mode by adding N-methyl-D-aspartate (20 microM) to the superfusing solution; after adding tetrodotoxin the membrane potential underwent rhythmical oscillations of 20-40 mV at 0.5-2 Hz. Baclofen (1 microM) and dopamine (30 microM) hyperpolarized the neurons; when the potential was restored to its original level, the oscillations of potential and/or burst firing were not observed, but the tonic firing pattern was restored. These effects of baclofen and dopamine were prevented by barium (1 mM), which also prevented the membrane hyperpolarization. Oscillations of membrane current of a similar frequency were observed when the somatic membrane was voltage-clamped at -60 mV; these were also blocked by barium (1 mM). It is concluded that the oscillations in membrane potential observed with N-methyl-D-aspartate are generated predominantly at a dendritic location which is not voltage-clamped with an electrode at the soma. Baclofen and dopamine inhibit the oscillations by increasing the potassium conductance and hyperpolarizing the dendrites. [less ▲]

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See detailTests standardisés de routine pour l'évaluation de la condition physique chez les chevaux d'endurance
Noel de Burlin, A; Art, Tatiana ULg; Amory, Hélène ULg et al

in Pratique Vétérinaire Equine (1994), 26

The purpose of this study was to try to assess the fitness of endurance horses by using a simple routine standardized treadmill exercise test performed before and after a training period. Seven endurance ... [more ▼]

The purpose of this study was to try to assess the fitness of endurance horses by using a simple routine standardized treadmill exercise test performed before and after a training period. Seven endurance horses aged 7 to 13 years, unfamiliar with the treadmill conditions and competing in international championship were tested twice in an air-conditioned laboratory, i.e. before and after a 4-month training period. The test was preceded by a 20 min warm-7 period and consisted of 2 min walk and 2 min trot (4.2 m/sec) with a slope of 0, 2, 4, 6, 8 and 10 The whole test lasted 45 min. Venous blood was sampled before and 4 min after each test. Heart rate was continuously recorded before, during and after the test with a cardiometer. Rectal temperature, respiratory rate and body weight were measured before and after the test. The completion of the test induced a significant decrease of the body weight, a significant increase in packed cell volume, cortisol, white blood cells, proportion of granulocytes, lactate, free fat acids and iso-enzyme LDH 5, and no change in the ions and in the activity of the other enzymes. Training did not induce significant changes in blood parameters, except in hacked cell volume and cortisol. Training induced a significant decrease in heart rate at all exercise intensities and during recovery. It was concluded that the test proposed in this study is simple, safe, suitable for horses unfamiliar with the treadmill and applicable in a 1-day clinic routine examination. In these conditions, the most reliable parameter for the assessment of fitness in endurance horses seems to be the heart rate recorded during 2 standardized tests performed before and after a training period [less ▲]

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See detailDimensionless critical shear stress evaluation from flume experiments using different gravel beds
Petit, François ULg

in Earth Surface Processes & Landforms (1994)

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See detailAspergillose chez les oiseaux marins échoués sur la côte belge
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Annales de Médecine Vétérinaire (1994), 138(4), 277-281

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species ... [more ▼]

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species. Debilitation and stress are favourable for the mycosis installation in captive wild birds (Zoo and rehabilitation centers). During 90-91 and 91-92 winters, 386 birds found dead at the belgian seashore were necropsied and 9 birds were carriers of specific lesions. Complementary investigations were undertaken. Most animals were oiled and had been kept for some time in rehabilitation centers. [less ▲]

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See detailCrystallization and X-ray diffraction study of the Streptomyces K15 penicillin-binding DD-transpeptidase.
Englebert, S.; Charlier, Paulette ULg; Fonze, E. et al

in Journal of Molecular Biology (1994), 241(2), 295-7

The 262 amino acid residue long DD-transpeptidase/penicillin-binding protein of Streptomyces K15 has been crystallized at room temperature by using the hanging drop vapour diffusion technique. The ... [more ▼]

The 262 amino acid residue long DD-transpeptidase/penicillin-binding protein of Streptomyces K15 has been crystallized at room temperature by using the hanging drop vapour diffusion technique. The crystals belong to the orthorhombic space group P2(1)2(1)2(1), with unit cell parameters a = 46.4 A, b = 54.1 A and c = 108.3 A. They contain one protein molecule per asymmetric unit and diffract to about 1.9 A. X-ray data have been collected to 2.0 A from a native crystal. The previously published amino acid sequence of the protein has been corrected at positions 71, 72, 113, 114 and 156. [less ▲]

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See detailIGF-I and IGFBP-3 increase independently of testosterone release during the onset of puberty in cattle
Renaville, Robert ULg; Sneyers, Myriam; Massart, Serge et al

in Growth Regulation (1994), 4(suppl 1), 116

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See detailMaastricht in beweging. Enkele bedenkingen na het Belgisch voorzitterschap van de Europese Unie
Flore, Daniel ULg; Troosters, R.

in Panopticon : Tijdschrift voor Strafrecht, Criminologie en Forensisch Welzijnswerk (1994)

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See detailQuand la chimie s’en mêle
Flandroy, P; Grandfils, Christian ULg

in le Journal du Médecin (1994), 16

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See detailThe Moorcock / Hawkwind Connection: Science Fiction and Rock & Roll Culture
Delville, Michel ULg

in Foundation: The Review of Science Fiction (1994)

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See detailConséquences microcirculatoires et cellulaires de l'endotoxine
D'Orio, Vincenzo ULg

in Réanimation (1994), 1

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See detailANOMALOUS PERTURBATIVE TRANSPORT IN TOKAMAKS DUE TO DRIFT-ALVEN-WAVE TURBULENCE
Thoul, Anne ULg; SIMILON, P. L.; SUDAN, R. N.

in Physics of Plasmas (1994), 1(3), 601-608

The method developed in Thoul, Similon, and Sudan [Phys. Plasmas 1, 579 (1994)] is used to calculate the transport due to drift-Alfven-wave turbulence, in which electromagnetic effects such as the ... [more ▼]

The method developed in Thoul, Similon, and Sudan [Phys. Plasmas 1, 579 (1994)] is used to calculate the transport due to drift-Alfven-wave turbulence, in which electromagnetic effects such as the fluttering of the magnetic field lines are important. Explicit expressions are obtained for all coefficients of the anomalous transport matrix relating particle and heat fluxes to density and temperature gradients in the plasma. Although the magnetic terms leave the transport by trapped electrons unaffected, they are important for the transport by circulating electrons. [less ▲]

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See detailImportance des insectes ravageurs des cereales stockees en Belgique.
Letellier, C.; Haubruge, Eric ULg; Gaspar, Charles ULg

in Parasitica (1994), 50(1-2),

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See detailEvaluation of agents used in osteoporosis: What are the needs ?
Reginster, Jean-Yves ULg

in Osteoporosis Japan (1994), 2

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See detailAlienating Language and Darl's Narrative Consciousness in As I Lay Dying
Delville, Michel ULg

in The Southern Literary Journal (1994)

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See detailPilot trial of combined administration of erythropoietin and granulocyte colony-stimulating factor to children undergoing allogeneic bone marrow transplantation.
Locatelli, F.; Zecca, M.; Ponchio, L. et al

in Bone Marrow Transplantation (1994), 14(6), 929-35

We carried out a pilot study to evaluate the combined use of recombinant human erythropoietin (rhEpo) and granulocyte colony-stimulating factor (G-CSF) for accelerating marrow engraftment in children ... [more ▼]

We carried out a pilot study to evaluate the combined use of recombinant human erythropoietin (rhEpo) and granulocyte colony-stimulating factor (G-CSF) for accelerating marrow engraftment in children given allogeneic bone marrow transplantation (BMT). Fifteen consecutive children were enrolled in this study; 13 completed it and were evaluable. Using analysis of variance, laboratory and clinical data referring to these children were compared with those of 15 patients previously treated with rhEpo alone and with those of 16 historical controls. Erythroid repopulation, evaluated sequentially through serum transferrin receptor and reticulocyte count, was similarly accelerated in children receiving rhEpo alone and in those receiving combined treatment. These latter, however, showed a further reduction in the total number of red blood cell units required to reach transfusion independence (1.1 +/- 0.7 in the study population vs 2.7 +/- 1.2 in rhEpo group vs 4.2 +/- 2.3 in historical controls; values are mean +/- 1 SD; p < 0.001). Neutrophil engraftment, i.e. time for neutrophils to reach 0.5 x 10(9)/l, was 11 +/- 3 days in children receiving combined treatment, significantly shorter than that of the control groups (16 +/- 3 and 18 +/- 5, respectively; p < 0.001). Acceleration of neutrophil recovery translated into fewer infections: days of fever were significantly reduced in the study population (4 +/- 2 vs 11 +/- 8 vs 15 +/- 6, respectively).(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailUtility of non-invasive ambulatory bood pressure monitoring in a hypertension clinic
Saint-Remy, Annie ULg; Dubois, Bernard ULg; Krzesinski, Jean-Marie ULg et al

in CVD Epidemiology newsletter (1994), 49(Spring), 50

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See detailIdentification Of Distinct Potyviruses In Mixedly-Infected Sweet-Potato By The Polymerase Chain-Reaction With Degenerate Primers
Colinet, D.; Kummert, J.; Lepoivre, Philippe ULg et al

in Phytopathology (1994), 84(1),

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See detailDetection des molecules responsables de l'activite biocide des feuilles de Boscia senegalensis (Pers.) Lam ex Poir. par echantillonage d'espace de tete et spectrometrie de masse couplee a la chromatographie en phase gazeuse.
Lognay, Georges ULg; Marlier, M.; Seck, D. et al

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(1),

Des échantillons de feuilles de Boscia senegalensis (Prns.) I.ev ex Porn. ont été tnaintenus dans des conditions contrôlées sous un flux d'hélium, à l'intérieur d'une.platine de désorption thermique ... [more ▼]

Des échantillons de feuilles de Boscia senegalensis (Prns.) I.ev ex Porn. ont été tnaintenus dans des conditions contrôlées sous un flux d'hélium, à l'intérieur d'une.platine de désorption thermique directement connectée à un GC-MS. A côté du trans-2-hexénal, responsable de la note "verte" des feuilles, l'isothiocyanate de méthyle et le cyanure de méthyle (acétonitrile) ont été détectés. Ces deux produits se sont formés par dégradation enzymatique in situ d'un précurseur, la glucocapparine. Ils ont été caractérisés par leur spectre de masse. La libération de cyanure de méthyle à partir d'échantillons biologiques est expliquée. [less ▲]

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See detailYeast excision repair RAD2 encodes a single-stranded DNA endonuclease
Habraken, Yvette ULg; Sung, Partick; Prakash, Louise et al

in Nature (1993), 366

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See detailMagnetic Eden model
Ausloos, Marcel ULg; Vandewalle, Nicolas ULg; Cloots, Rudi ULg

in Europhysics Letters [=EPL] (1993), 24(8), 629-634

We introduce the <<Magnetic Eden Model(s)>>. It consists in the usual Eden growth model(s), but allowing for the elements of the growth to have an extra degree of freedom (a <<spin>>). The growth is ... [more ▼]

We introduce the <<Magnetic Eden Model(s)>>. It consists in the usual Eden growth model(s), but allowing for the elements of the growth to have an extra degree of freedom (a <<spin>>). The growth is controlled by a condition depending on the <<magnetic state>> of the perimeter (through some <<spin coupling>>) and an external parameter, the <<magnetic field>>. Even though these words seem to refer to some <<energetic condition>> the growth model is of purely kinetic origin. This is demonstrated by exactly solving the 1-dimensional growth model for a semi-open chain, and, e.g. finding the correlation functions. In two-dimensions, simulations of clusters lead us to show that the perimeter growth exponent is coupling dependent. We show the morphologies of growth clusters on a <<phase diagram>> and indicate the <<physical origin>> and transition(s) between compact and lacunar clusters. [less ▲]

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See detailFully Automated Determination of Sulfamethazine in Ovine Plasma Using Solid-Phase Extraction on Disposable Cartridges and Liquid Chromatography
Hubert, Philippe ULg; Chiap, Patrice ULg; Evrard, Brigitte ULg et al

in Journal of Chromatography. A (1993), 622(1), 53-60

An automatic sample preparation procedure followed by on-line injection of the sample extract into a HPLC system has been developed for the quantitative analysis of sulfamethazine and its N4-acetyl ... [more ▼]

An automatic sample preparation procedure followed by on-line injection of the sample extract into a HPLC system has been developed for the quantitative analysis of sulfamethazine and its N4-acetyl metabolite in ovine plasma. The sample clean-up was performed by solid-phase extraction (SPE) on C18 disposable extraction cartridges (DECs). All the sample handling operations were effected by a robotic auto-sampler. The DEC was first conditioned with methanol and phosphate buffer pH 7.4. After loading 1.0 ml of plasma sample onto the DEC, the latter was washed with the same buffer. The elution step was performed with methanol (0.25 ml) and the eluate was then diluted by adding 0.75 ml volume of phosphate buffer pH 6.4. A 20-microliters volume of the resultant solution was injected onto an octadecyl silica column preceded by a short guard column. The HPLC mobile phase was methanol-phosphate buffer pH 6.4 (25:75, v/v). Sulfamethazine and N4-acetylsulfamethazine were determined photometrically at 262 nm. Under these conditions, linear calibration curves ranging from 2 to 250 micrograms ml-1 have been obtained for both compounds. Drug recoveries were higher than 90% and typical relative standard deviation values were 0.7% (within-day) and 2.0% (between-day) at a plasma concentration of 50 micrograms ml-1. [less ▲]

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See detailAnionic polymerization of acrylic monomers. 11 NMR investigation of the mixed complexation of methyl α-lithioisobutyrate and lithium chloride
Wang, Jin-Shan; Warin, R.; Jérôme, Robert ULg et al

in Macromolecules (1993), 26

Solutions of methyl α-lithioisobutyrate (MIBLi) in THF added with various amounts of lithium chloride (LiCl) have been analyzed by Li-7 NMR spectroscopy in a wide range of temperatures. Although below ca ... [more ▼]

Solutions of methyl α-lithioisobutyrate (MIBLi) in THF added with various amounts of lithium chloride (LiCl) have been analyzed by Li-7 NMR spectroscopy in a wide range of temperatures. Although below ca. 205 K tetramers of MIBLi have been reported to be in equilibrium with dimers, 1/1 and 2/1 LiCl/MIBLi mixed complexes instantaneously form upon the addition of 1 and 2 mol equiv of LiCl, respectively. Further addition of LiCl more likely promotes the formation of a less stable 3/1 complex. Both 1/1 and 2/1 adducts are stable between -80-degrees-C and at least +12-degrees-C. From C-13 NMR spectroscopy, it appears that the addition of an equimolar amount of LiCl to the MIBLi solution in THF is at the origin of a ca. 7.0 ppm upfield shift of the metalated α-carbon compared to the tetrameric MIBLi species and a ca. 1.0 ppm downfield shift with respect to the dimeric MIBLi. However, the charge distribution over the carbanion does not change anymore when the amount of LiCl exceeds 1 mol equiv. In contrast to nonligated MEBLi, the OR group has a considerable rotational freedom in LiCl-modified MIBLi. A comparison of the structure and dynamics of the LiCl-modified MIBLi species in THF at 197 K with the characteristic features of the anionic polymerization of MMA under the same conditions suggests that the formation of one type of LiCl-complexed species has a decisive effect on the control of the living polymerization of MMA. This conclusion is in agreement with a kinetic study carried out by Muller for the same system. [less ▲]

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See detailSelective gravitational microlensing and line profile variations in the BAL quasar H 1413+117
Hutsemekers, Damien ULg

in Astronomy and Astrophysics (1993), 280

In order to interpret the spectral differences observed between the four images of the gravitationally lensed broad absorption line (BAL) quasar H 1413+117, we have investigated the effect on the line ... [more ▼]

In order to interpret the spectral differences observed between the four images of the gravitationally lensed broad absorption line (BAL) quasar H 1413+117, we have investigated the effect on the line profiles of the selective magnification of individual BAL clouds by gravitational microlenses. Since microlenses magnify both the selected cloud and the whole BAL region, this effect is only differential, and general constraints on its capability to produce spectral variations have been derived. Considering simple but realistic models for the microlenses, we find that the selective magnification of a relatively large optically thick BAL cloud can be at the origin of the spectral differences reported between the components of H 1413+117. However, a very precise configuration is needed: the magnified cloud must be at the border of the BAL region which must itself partially lie in a region of strong de-magnification. The fine tuning of the parameters mecessary to reproduce the observations either seriously questions this kind of interpretation or puts strong constraints on the lensing models. Another interpretation of the observed line profile differences in terms of effects due to microlensing is also briefly discussed. [less ▲]

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See detailComplement activation during cardiopulmonary bypass in infants and children: Relation to postoperative multiple system organ failure
Seghaye, Marie-Christine ULg; Duchateau, J.; Grabitz, R. G. et al

in Journal of Thoracic and Cardiovascular Surgery (1993), 106(6), 978-987

Twenty-nine children 3 months to 17 years of age undergoing operations for congenital heart disease were included in this prospective study. Complement activation, activation of the plasma contact system ... [more ▼]

Twenty-nine children 3 months to 17 years of age undergoing operations for congenital heart disease were included in this prospective study. Complement activation, activation of the plasma contact system, leukocytes, leukocyte elastase release, and C-reactive protein were studied during and after cardiopulmonary bypass for the first postoperative week and related to multiple system organ failure occurring in eight (27.5 %) of the 29 children. During cardiopulmonary bypass complement activation via the alternative pathway as indicated by significant conversion of C3 (expressed by C3d/C3) and abnormally high C5a values at the end of cardiopulmonary bypass without consumption of C4 was shown in all children. At the end of cardiopulmonary bypass, C3 conversion was significantly higher in the eight patients with multiple system organ failure than in the others (p < 0.05), whereas no difference in C5a level was shown. All children had a significant increase in leukocyte count directly after protamine administration (p < 0.0001) and elastase release during cardiopulmonary bypass that was significantly higher in patients with multiple system organ failure than in those without (p < 0.05). Consumption of prekallikrein as an indicator of activation of the Hageman system was not detectable during cardiopulmonary bypass in any child. After cardiopulmonary bypass, in patients without multiple system organ failure, C3d/C3 decreased and reached preoperative values within the first postoperative week, whereas, in patients with multiple system organ failure, C3d/C3 increased further, reaching a maximal value on the third postoperative day. In comparison with patients without multiple system organ failure, patients with multiple system organ failure showed a severe decrease of C4 (with minimal values on the third postoperative day), suggesting consumption by activation of the classic pathway of the complement system or a hepatic synthesis deficiency. Prekallikrein values were also significantly lower in patients with multiple system organ failure than in the others, with a maximal difference on the third postoperative day (p < 0.005). C-reactive protein was significantly lower in patients with multiple system organ failure than in the others for the first 2 postoperative days (p < 0.05), probably because of severe hepatic failure in patients with multiple system organ failure. This study demonstrates that, in children, cardiopulmonary bypass induces complement activation principally via the alternative pathway. It suggests a relationship between complement activation and multiple system organ failure observed in the postoperative period. Furthermore, it points out the role of multiple system organ failure itself on the C3 conversion and on the synthesis of the markers of the inflammatory response in children after heart operations. [less ▲]

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See detailOppervlakte-biopsie
Nikkels, Arjen ULg; Pierard-Franchimont, Claudine ULg; Pierard, Gérald ULg

in Nederlands Tijdschrift voor Dermatologie en Venereologie (1993), 3

Superficial skin surface stripping (SSSS) enables the study of the outermost cell layers of the stratum corneum. In this article we review the diagnostic value and the research possibilities offered by ... [more ▼]

Superficial skin surface stripping (SSSS) enables the study of the outermost cell layers of the stratum corneum. In this article we review the diagnostic value and the research possibilities offered by SSSS. This technique is non invasive and provides information useful in the differential diagnosis of erythematosquamous and eczematous lesions and pigmented neoplasms. For research purposes SSSS can also be used as substratum for scanning electron microscopic assessments and biochemical analysis. [less ▲]

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See detailSome Principles and Applications of Adaptive Mathematical Morphology for Range Imagery
Verly, Jacques ULg; Delanoy, Richard L.

in Optical Engineering : The Journal of the Society of Photo-Optical Instrumentation Engineers (1993), 32(12), 3295-3306

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See detailLe come back de Nyles Jones a.k.a. GUITAR GABRIEL
Sacré, Robert ULg

in Soul Bag (1993), (129),

Vie et oeuvre de Robert Lewis 'Nyles' JONES ou Guitar Gabriel

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See detailIpriflavone: Pharmacological Properties and Usefulness in Postmenopausal Osteoporosis
Reginster, Jean-Yves ULg

in Bone and Mineral (1993), 23(3), 223-32

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and ... [more ▼]

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and in vivo for IP and its metabolites. Their mechanisms of action on bone are not yet fully elucidated but some of them are widely accepted. IP does not possess, per se, any estrogenic activity. It appears that IP-related inhibition of bone resorption might be mediated by an indirect effect on osteoclast and related to an inhibition of recruitment and/or differentiation of pre-osteoclast, maybe through a modulation of osteoblast response to PTH. Clinical studies in Paget's disease of bone or primary hyperparathyroidism have confirmed preferential inhibition of bone resorption suggesting a clinical interest in postmenopausal osteoporosis. Preliminary (1 year) results of double blind placebo controlled studies designed in postmenopausal and senile osteoporosis confirm a reduction in bone turnover rate in patients treated with 600 mg/day of IP, resulting in a significant bone-sparing effect both at lumbar and radial levels. All clinical and pharmacological trials confirm a very good tolerance of IP with a frequency of adverse reactions equal to that observed during administration of a placebo. Providing ongoing studies will confirm the actual promising preliminary results, IP seems a very interesting new non hormonal approach for prevention and treatment of postmenopausal and senile osteoporosis. [less ▲]

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See detailClonage par greffe de blastomère: naissance d'un premier veau
Ectors, Fabien ULg; Delval, Alain; Touati, Kamal ULg et al

in Annales de Médecine Vétérinaire (1993), 137(8), 573-574

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See detailField Efficacy of Injectable Moxidectin in Cattle Naturally Infested with Chorioptes Bovis and Sarcoptes Scabiei
Losson, Bertrand ULg; Lonneux, J. F.

in Veterinary Parasitology (1993), 51(1-2), 113-21

Field efficacy of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bovis and Sarcoptes scabiei. Eight animals were allocated to two groups of four ... [more ▼]

Field efficacy of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bovis and Sarcoptes scabiei. Eight animals were allocated to two groups of four animals each, based on parasitological and clinical status. Animals of the treated group received one subcutaneous injection of injectable moxidectin at 0.2 mg kg-1 body weight on Day 0. Individuals of the control group received emergency treatment of a single injection of moxidectin at 0.2 mg kg-1 body weight on Day 28. Efficacy was assessed by (a) taking skin samples from each animal on Days 0, 7, 14, 21, 28, 42 and 56 and observing the numbers of viable mite stages and species and (b) clinical examination of animals on Days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated for each animal on Days 0, 28 and 56. On the basis of the geometric means from treated and control animals, the percentage reductions in the total numbers of living C. bovis mites on Days 7, 14, 21 and 28 were 69, 87, more than 99 and 98, respectively. However, at the end of the trial, only two animals were negative for C. bovis. The percentage reductions in the total numbers of S. scabiei on Days 7, 14, 21 and 28 were 93, 100, 100 and 100, respectively. Clinical indices of the treated animals showed a sharp decrease in the affected body surface area from a mean of 43.6% on Day 0 to 0.9% and 0% on Days 28 and 56, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailEtre ou non branché aux médias
Leclercq, Dieudonné ULg

in Emergence. Revue proposée par l'ICC en collaboration avec MEDIA ANIMATION et le CFA (1993), 21

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