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See detailLigniculture et maintien de la fertilité des sols dans l'Ouest-Cameroun
Njoukam, Raphaël; Bock, Laurent ULg; Hebert, Jacques ULg et al

in Bois et Forêts des Tropiques (1996), (249), 33-49

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See detailA site with foliicolous lichens in Belgium
van den Boom, Pieter; Sérusiaux, Emmanuël ULg

in Belgian Journal of Botany (1996), 129

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See detailDissociation of increases in plasma insulin-like growth factor I and testosterone during the onset of puberty in bulls
Renaville, Robert ULg; Massart, Serge; Sneyers, M. et al

in Journal of Reproduction and Fertility (1996), 106(1), 79-86

The present study was conducted to examine the relationship between plasma concentrations of testosterone, insulin-like growth factor I (IGF-I) and IGF-binding proteins (IGFBPs) during puberty, in male ... [more ▼]

The present study was conducted to examine the relationship between plasma concentrations of testosterone, insulin-like growth factor I (IGF-I) and IGF-binding proteins (IGFBPs) during puberty, in male calves treated with GnRH or testosterone propionate. Twelve male Holstein calves (10 weeks old) were assigned to the control group (n = 6), the GnRH-treated group (n = 3) or the testosterone-treated group (n = 3). For 8 weeks, the GnRH-treated group received a single i.v. injection of GnRH (0.5 mu g kg(-1) body mass) each day while the testosterone-treated group received an i.m. injection of testosterone propionate (0.5 mg kg(-1) body mass) twice a day. The calves were studied until they were 200 days old. Hormone treatments were stopped one month after puberty was reached in the control group. Blood samples were collected every 30 min for 8 h every third day. Hormone concentrations were determined by radioimmunoassay. Western ligand blotting and immunoblotting, using monoclonal antibodies against IGFBP-2, and IGFBP-3, were used to characterize the IGF-binding proteins. In the control group, puberty occurred at about 120 days of age and was associated with an increase in concentrations of testosterone, IGF-I and IGFBP-3 and a decrease in concentration of IGFBP-2. In the GnRH-treated group, plasma testosterone remained low until 8 weeks after establishment of puberty in the control group (4 weeks after the end of treatment). In the testosterone-treated group, testosterone was high during the treatment period and then decreased to prepubertal values when treatment was stopped. Testosterone values increased again to reach postpubertal values 5 weeks after the end of hormone treatment. Nevertheless, independent of testosterone status, the profile of IGF-I and the IGFBPs in the GnRH- and testosterone-treated groups were parallel to that reported for the control group with the transition from prepubertal to adult values at about 120 days of age. In conclusion, concentrations of testosterone, IGF-I and IGFBP-3 increase together, but probably independently, during the onset of puberty in male calves. [less ▲]

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See detailMiospores from the type locality of the middle Famennian Esneux Formation in the Ourthe Valley, eastern Belgium
Loboziak, S; Avkhimovich, V I; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1996), 119(2), 111-118

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See detailCompte rendu de P. CONTAMINE, La guerre au Moyen Âge
Marchandisse, Alain ULg

in Moyen Age (Le) (1996), 102

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See detailLes morphinomimétiques en réanimation
Lamy, Maurice ULg; Joris, Jean ULg; Damas, Pierre ULg et al

in Revue Janssen-Cilag (1996)

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See detailCalcium et squelette, base physiologique d’une prévention
Reginster, Jean-Yves ULg

in Les Nouvelles de Rhumatologie (1996), 1

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See detailLa santé face aux nouveaux mécanismes de production et de gestion des inégalités sociales
Gavray, Claire ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1996), 11-12

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See detailLe Rohypnol, une drogue dure amnésiante : résultats d'une recherche en médecine de famille
Jamoulle, Marc ULg

in Psychotropes : Revue Internationale des Toxicomanies et des Addictions (1996), 2(2), 53-66

Objectifs : Etudier le profil de l'usage de médicaments chez les toxicomanes à l'héroïne Sujets et méthodes : 89 héroïnomanes, enrôlés dans un programme de maintenance par la méthadone en médecine de ... [more ▼]

Objectifs : Etudier le profil de l'usage de médicaments chez les toxicomanes à l'héroïne Sujets et méthodes : 89 héroïnomanes, enrôlés dans un programme de maintenance par la méthadone en médecine de famille, ont fait l'objet d'une enquête. Les patients pharmacophiles et leurs préférences ont été identifiés par questionnaire. L'enregistrement d'interviews face à face semistructurés a permis de mettre en évidence le profil de 56 patients ainsi que le tableau clinique résultant de l'abus de médicament. Une revue bibliographique et une investigations auprès de praticiens de différents pays renforcent l'étude. Résultats : 60%(53/89) des consultants ont abusé de médicaments au moins une fois. Le Rohypnol™ (Flunitrazépam), un hypnotique puissant, est placé en premier choix comme succédané de l'héroïne par 66% de ces utilisateurs abusifs. " Etre en Roche " est une expression utilisée par les toxicomanes euxmêmes pour désigner le tableau clinique consécutif à la prise diurne d'un ou plusieurs (jusqu'à 30 c à 2mg par jour) comprimés de Rohypnol™, associé ou non à l'alcool. Un comprimé de Rohypnol™est appelé un " Roche " et un utilisateur compulsif un " Rocheman ". Le tableau clinique est caractérisé par un état d'obnubilation ( « Etre ravagé, pété, mort »), une dysarthrie, une sensation d'invincibilité, une perte d'inhibition avec possible passage à l'acte et agression suivis d'endormissement et d'amnésie antérograde totale. L'information concernant la dangerosité de ce produit n'a pas été diffusée . Le Rohypnol™ est une drogue de rue dans tous les pays étudiés. Conclusions : Le Rohypnol™ est une drogue dure, succédané de l'héroïne et un amnésiant puissant. Ce produit est dangereux par son pouvoir amnésiant et désinhibant. Ce produit n'a plus de place en thérapeutique. [less ▲]

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See detailIn vitro evaluation of lipid matrices for the development of a sustained-release sulfamethazine bolus for lambs
Evrard, Brigitte ULg; Delattre, Luc ULg

in Drug Development & Industrial Pharmacy (1996), 22(2), 111-118

The aim of this study is the development of a high-density bolus to be given to lambs in order to release sulfamethazine during 4 days after a single oral administration. The suitability of 12 lipid ... [more ▼]

The aim of this study is the development of a high-density bolus to be given to lambs in order to release sulfamethazine during 4 days after a single oral administration. The suitability of 12 lipid matrix formulations was assessed in order to maintain the integrity of the tablet even after complete dissolution of the active substance. The influence of both nature and concentration of the lipid excipient on the in vitro release of sulfamethazine was investigated. The influences of the granulation method and of the compression force were assessed on a formulation containing Cutina® HR as a binding and sustained-release agent. Finally, stability tests showed that the in vitro release characteristics remain unchanged during storage. [less ▲]

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See detailFault re-activation, stress interaction and rupture propagation of the 1981 Corinth earthquake sequence
Hubert, Aurelia ULg; King, G. C. P.; Armijo, R. et al

in Earth & Planetary Science Letters (1996), 142

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See detailAn efficient procedure for the production of fatty acid hydroperoxides from hydrolyzed flax seed oil and soybean lipoxygenase.
Fauconnier, Marie-Laure ULg; Marlier, M.

in biotechnology techniques (1996), 10(11), 839-844

Production of 13-linolenic acid hydroperoxides Tom hydrolyzed flax seed oil using lipoxygenase extracted Tom soybean seedshas been achieved with high transformation yields (60 g.l.-1h-1) with a high ... [more ▼]

Production of 13-linolenic acid hydroperoxides Tom hydrolyzed flax seed oil using lipoxygenase extracted Tom soybean seedshas been achieved with high transformation yields (60 g.l.-1h-1) with a high purity (94 % of i3-isomers) in a 10 liter reactor without addition of any solvent or surfactant. The reaction limiting factor is, probably, the accessibility of the substrate to the enzyme. [less ▲]

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See detailLa communauté des citoyens de D. Schnapper
Martiniello, Marco ULg

in New Community (1996), 22(1), 165-166

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See detailDeficient Habituation of Evoked Cortical Potentials in Migraine: A Link between Brain Biology, Behavior and Trigeminovascular Activation?
Schoenen, Jean ULg

in Biomedicine & Pharmacotherapy (1996), 50(2), 71-8

According to recent evoked potential studies, a fundamental, probably protective, feature of cortical information processing, ie, response habituation during stimulus repetition, is abnormal in migraine ... [more ▼]

According to recent evoked potential studies, a fundamental, probably protective, feature of cortical information processing, ie, response habituation during stimulus repetition, is abnormal in migraine between attacks. The deficient habituation is found for different sensory modalities and experimental paradigms: pattern-reversal visual evoked potentials (same stimulus at a constant intensity), cortical auditory evoked potentials (same stimulus at increasing intensities) and auditory event-related potentials obtained in a passive "oddball" paradigm (novel stimulus). The abnormal information processing is an interictal cortical dysfunction most likely due to inadequate control by the so-called "state-setting, chemically-addressed pathways" originating in the brain stem, in particular by the serotonergic pathway, leading to a low preactivation level of sensory cortices. We suggest that it may play a pivotal role in migraine pathogenesis in conjunction with the reported decrease of brain mitochondrial energy reserve, by favouring a rupture of metabolic homeostasis and biochemical shifts capable of activating the trigeminovascular system and thus capable of producing a migraine attack. We postulate that both the deficient habituation in information processing and the deranged oxygen metabolism may have behavioral correlates. Which of these abnormalities are inherited, acquired or both remains to be determined. [less ▲]

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See detailHacia una cartografía del boom. Una polémica en Zona Franca (ag.-dic.1972).
Vanden Berghe, Kristine ULg

in América. Cahiers du CRICCAL (1996), 15/16

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See detailCritical Evaluation of the DNA-methyl Green Assay: Application to Some Indole Alkaloids
Bonjean, K.; De Pauw-Gillet, Marie-Claire ULg; Bassleer, R. et al

in Phytotherapy Research (1996), 10

A DNA-methyl green colorimetric microassay for the detection of agents that interact with DNA was assessed with reference molecules (doxorubicin, ellipticine, melinonine F, dihydroflavopereirine, cis-Pt ... [more ▼]

A DNA-methyl green colorimetric microassay for the detection of agents that interact with DNA was assessed with reference molecules (doxorubicin, ellipticine, melinonine F, dihydroflavopereirine, cis-Pt, mitomycin C, emetine or colchicine). This test showed some promise as a screening technique for substances that intercalate partly or totally into the DNA helix but it is not suitable for substances that bind covalently to DNA. An application of this test to a number of indole alkaloids was also performed. Cryptolepine, serpentine, alstonine and matadine induced a reduction of the colour of the solution, so indicating an interaction with DNA. [less ▲]

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See detailSimulation of pumping and artificial recharge in the phreatic aquifer near Bucarest (Romania)
Stefanescu, Christian; Dassargues, Alain ULg

in Hydrogeology Journal (1996), 4(3), 72-83

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See detailTransition probabilities for [Ni I] and [Ni II] lines
Quinet, Pascal ULg; Le Dourneuf, M

in Astronomy and Astrophysics. Supplement Series (1996), 119

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See detailEffects of PEEP on venous return
LAMBERMONT, Bernard ULg; DETRY, Olivier ULg; Defraigne, Jean-Olivier ULg et al

in American Journal of Respiratory & Critical Care Medicine (1996), 2

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See detailCytochemistry of the tergite epicuticle of Glomeris marginata (Villers) (MYRIAPODA, DIPLOPODA): preliminary experimental results
Compère, Philippe ULg; Defise, Stéphane; Goffinet, Gerhard ULg

in Mémoires du Muséum d'Histoire naturelle (Paris) - Acta Myriapodologica (1996), 169

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See detailIntestinal Permeability in Crohn's Disease
Franchimont, D.; Louis, Edouard ULg; Simon, Sarah ULg et al

in Acta Gastro-Enterologica Belgica (1996), 59(1, Jan-Mar), 15-9

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the ... [more ▼]

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the involvement of an abnormal intestinal permeability in the pathogenesis of Crohn's disease, as a primary or secondary defect. We discuss the potential usefulness of the measure of intestinal permeability in Crohn's disease activity assessment, relapse prediction and efficacy of treatment. [less ▲]

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See detailInfections oculaires traumatiques et iatrogènes: prélèvements et rôle du laboratoire
Melin, Pierrette ULg

in Bulletin de la Société Belge d'Ophtalmologie (1996), 260

Ocular inflammations may be due to a variety of diseases, and microorganisms play a major role in both acute and chronic eye diseases. Treatment of serious infections needs a good microbiological ... [more ▼]

Ocular inflammations may be due to a variety of diseases, and microorganisms play a major role in both acute and chronic eye diseases. Treatment of serious infections needs a good microbiological diagnostic. The indications and techniques for investigations are determined by the site of infection, severity of the process, and knowledge of the likely responsible organisms. Immediate inoculation of specimens on culture media in the examining room is often recommended. This article describes organisms associated with ocular infections, and is designed to assists ophthalmologists in the collection, processing and transport of specimens. [less ▲]

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See detailPhénomènes karstiques en milieux non carbonatés. Etudes de cavités et problématique de leur développement au Niger Occidental
Willems, Luc ULg; Pouclet, André; Lenoir, François et al

in Zeitschrift für Geomorphologie (1996)

The study of several caves in siliceous formations belonging to the Precambrian basement and its Cenozoic sedimentary cover brings to the fore the importante of an underground drainage network in relation ... [more ▼]

The study of several caves in siliceous formations belonging to the Precambrian basement and its Cenozoic sedimentary cover brings to the fore the importante of an underground drainage network in relation with crustal fracturation. This network guides the waler transfer from the land surface to the depth and generates géomorphologic phenomena similar to those in calcareous areas. The study of caves in a siliceous environmemts shows the importance of solution phenomena in their formation and also in that of West Niger landscapes. Therfore, a general model of topographic evolution îs proposed. [less ▲]

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See detailElectrical microenvironment influence on the hydrolytic activity of free and immobilised Yarrowia lipolytica lipase
Paquot, Michel ULg; Deleu, Magali ULg; Beaufils, C. et al

in Biotechnology Letters (1996), 18(1), 73-78

The role of electrical properties of interfaces upon the activity of free and immobilised Yarrowia lipolytica lipase has been investigated. Sodium taurocholate and Sedipur 400, an anionic polyacrylamide ... [more ▼]

The role of electrical properties of interfaces upon the activity of free and immobilised Yarrowia lipolytica lipase has been investigated. Sodium taurocholate and Sedipur 400, an anionic polyacrylamide, enhance the negative character of the fatty droplets of substrate and tend to improve the lipolytic activity while the cationic polyacrylamide (Sedipur 900) has opposite effects. Ca+ which reduces the fatty droplets charge as Sedipur 900, is however a good activator of the enzyme. The role of electrical properties on the optimum pH of the immobilised enzyme is clearer. Immobilisation of the lipase on a positively charged support shifts its optimum pH to acidic pH by repulsion towards H+ ions around the support. [less ▲]

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See detailA systematic view on medical informatics.
Hasman, A; Haux, R; Albert, Adelin ULg

in Computer Methods & Programs in Biomedicine (1996), 51(3), 131-9

Medical informatics is defined as the scientific discipline concerned with the systematic processing of data, information and knowledge in medicine and health care. The domain of medical informatics ... [more ▼]

Medical informatics is defined as the scientific discipline concerned with the systematic processing of data, information and knowledge in medicine and health care. The domain of medical informatics (including health informatics), its aim, methods and tools, and its relevance to other disciplines in medicine and health sciences are outlined. It is recognized that one of the major tasks of medical informatics is modelling processes. In this context, biological, communication, decision, engineering, educational, organizational and computational processes are distinguished and described. [less ▲]

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See detailInteraction Of The Macrolide Azithromycin With Phospholipids .2. Biophysical And Computer-Aided Conformational Studies
Montenez, Jp.; Vanbambeke, F.; Piret, J. et al

in European Journal of Pharmacology (1996), 314(1-2), 215-27

In a comparison paper, we show the azithromycin causes a lysosomal phospholipidosis in cultured cells, binds in vitro to negatively charged bilayers without causing aggregation or fusion, and inhibits ... [more ▼]

In a comparison paper, we show the azithromycin causes a lysosomal phospholipidosis in cultured cells, binds in vitro to negatively charged bilayers without causing aggregation or fusion, and inhibits lysosomal phospholipase A1. In this paper, we show that azithromycin decreases the mobility of the phospholipids in negatively charged liposomes (using 31P nuclear magnetic resonance) and that it increases the fluidity of the acyl chains close to the hydrophilic/hydrophobic interface, but not deeper into the hydrophobic domain (assessed by measuring the fluorescence polarization of trimethylammonium-diphenylhexatriene and diphenyhexatriene, respectively). Computer-aided conformational analysis of mixed monolayers of azithromycin and phosphatidylinositol shows that the drug can be positioned largely in the hydrophobic domain, but close to the interface, with the macrocycle facing the C1 of the fatty acids (allowing the N9a endocyclic tertiary amine to interact with the phospho-groups), the cladinose located on the hydrophobic side of the lipid/water interface and the desosamine projected into the hydrophobic domain. This position is consistent with the experimental data. Analysis of virtual molecules shows that this unanticipated behavior to the shielding of the ionizable N3' amino-group in the desosamine by methyl-groups, and to the wide dispersion of hydrophobic domains all over the molecule. The interaction of azithromycin with phospholipids may account for some of its unusual pharmacokinetic properties and for its potential to cause lysosomal phospholipidosis. [less ▲]

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See detailMutation analysis of the pyruvate dehydrogenase E1 alpha gene in eight patients with a pyruvate dehydrogenase complex deficiency.
Lissens, W.; De Meirleir, L.; Seneca, S. et al

in Human mutation (1996), 7(1), 46-51

Most of the mutations causing deficiency of the pyruvate dehydrogenase (PDH) complex are in the X-linked E1 alpha gene. We have developed a rapid screening method for the detection of mutations in this ... [more ▼]

Most of the mutations causing deficiency of the pyruvate dehydrogenase (PDH) complex are in the X-linked E1 alpha gene. We have developed a rapid screening method for the detection of mutations in this gene using reverse transcription of total RNA, polymerase chain reaction amplification of the whole coding region of the gene and single-strand conformation polymorphism (SSCP) analysis. With this method, we studied eight patients with a PDH complex deficiency, using cultured fibroblasts. In all patients, aberrant SSCP patterns were found and, after sequencing of the corresponding fragments, we were able to identify six new mutations and two mutations already described previously. The mutations are point mutations leading to amino acid substitutions (5) and direct repeat insertions (3). The presence of the mutations was confirmed in genomic fibroblast DNA. The 4 female patients were shown to carry both a normal and a mutated E1 alpha gene. [less ▲]

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See detailImpairement of Memory for spatial Context in Schizophrenia
Rizzo, L.; Danion, J.M.; Van der Linden, Martial ULg et al

in Neuropsychology (1996), 10

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See detailStructure and bonding in liquid tellurium
Bichara, C.; Raty, Jean-Yves ULg; Gaspard, Jean-Pierre ULg

in Physical Review. B, Condensed Matter and Materials Physics (1996), 53(1), 206-211211

The atomic structure and bonding mechanism in liquid tellurium have been investigated by a tight-binding Monte Carlo simulation. On melting, the chain structure of the crystal is preserved in spite of ... [more ▼]

The atomic structure and bonding mechanism in liquid tellurium have been investigated by a tight-binding Monte Carlo simulation. On melting, the chain structure of the crystal is preserved in spite of some significant changes in the local atomic environment. A third covalent bond appears with a bond length (widely distributed around 3.15 Aring) intermediate between those characteristic of the crystal. A short-long alternation of the bonds takes place within the chains, in agreement with the most recent extended X-ray-absorption fine structure measurements. In addition, the bond angle within the chains is reduced. Our calculations clearly prove that these effects are due to the electronic interaction between the lone pair orbitals. The subsequent broadening of the lone pair band is responsible for the semiconductor to metal transition that takes place upon melting. [less ▲]

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See detailTables quinquennales
Lecocq, Pascale ULg

in Actualités du droit (1996)

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See detailOne-pot enzymatic synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc sequence with in situ UDP-Gal regeneration.
Hokke, Cornelis H; Zervosen, Astrid ULg; Elling, Lothar et al

in Glycoconjugate Journal (1996), 13(4), 687-92

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely ... [more ▼]

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely, sucrose synthase, UDP-Glc 4'-epimerase, UDP-Gal:GlcNAc beta 4-galactosyltransferase and UDP-Gal:Gal beta 1-->4GlcNAc alpha 3-galactosyltransferase, Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was formed in a 2.2 mumol ml-1 yield starting from the acceptor GlcNAc beta 1-->O-(CH2)8COOCH3. This is an efficient and convenient method for the synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc epitope which pays an important role in various biological and immunological processes. [less ▲]

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See detailCarotid Surgery in Octogenarians: Is It Worthwhile?
VAN DAMME, Hendrik ULg; Lacroix; Desiron, Quentin ULg et al

in Acta Chirurgica Belgica (1996), 96(2), 71-7

Controversy surrounds the role of carotid endarterectomy in octogenarians. Although the prognosis of severe degree carotid stenosis is more ominous in the elderly, operative risk seems more important in ... [more ▼]

Controversy surrounds the role of carotid endarterectomy in octogenarians. Although the prognosis of severe degree carotid stenosis is more ominous in the elderly, operative risk seems more important in the aged. To evaluate the presumed detrimental effect of advanced age on the mortality-morbidity of carotid endarterectomy, the authors reviewed their common experience with carotid surgery in patients aged 80 years or more. From 1980 to 1994, 129 octogenarians were operated on for occlusive carotid artery disease in two university hospitals. The data for these patients, 80 years of age and older (group 1) are compared to these for a large middle age group (less than 80 years) (group 2) operated by the same surgeons during that period. The baseline characteristics of both groups were similar, except for smoking, diabetes and previous myocardial revascularization, more prevalent in the younger age group. In the elderly group prophylactic surgery for asymptomatic stenosis was done in 36%, versus 40% of the middle aged patients, and for stroke in evolution in 8% versus 4% (p < 0.05). The perioperative stroke rate was 0.8% in the group older than 80 years, compared to 1.2% for non octogenarians (NS). The operative mortality was similar for both age groups (2.3 and 1.5 respectively). The long-term results gave a similar outlook for both age groups. The 5-year stroke-free rate reached 89% for group 1 versus 91% for group 2. The 5-year survival rate, however, was less for the elderly patients (47% versus 77%, mean follow-up periods of 30 and 49 months). These results suggest that carotid endarterectomy can be safely done in elderly patients, with a similar risk/benefit ratio as for the younger patients. Advanced age, by itself, is not to be considered as contraindication to carotid surgery. [less ▲]

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See detailPenicillin and Beyond: Evolution, Protein Fold, Multimodular Polypeptides, and Multiprotein Complexes
Ghuysen, Jean-Marie ULg; Charlier, Paulette ULg; Coyette, Jacques et al

in Microbial Drug Resistance : Mechanism, Epidemiology, & Disease (1996), 2(2, Summer), 163-175

As the protein sequence and structure databases expand, the relationships between proteins, the notion of protein superfamily, and the driving forces of evolution are better understood. Key steps of the ... [more ▼]

As the protein sequence and structure databases expand, the relationships between proteins, the notion of protein superfamily, and the driving forces of evolution are better understood. Key steps of the synthesis of the bacterial cell wall peptidoglycan are revisited in light of these advances. The reactions through which the D-alanyl-D-alanine depeptide is formed, utilized, and hydrolyzed and the sites of action of the glycopeptide and beta-lactam antibiotics illustrate the concept according to which new enzyme functions evolve as a result of tinkering of existing proteins. This occurs by the acquisition of local structural changes, the fusion into multimodular polypeptides, and the association into multiprotein complexes. [less ▲]

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See detailCellular Pathways Involved In The Ex Vivo Expression Of Bovine Leukemia Virus
Kerkhofs, P.; Adam, E.; Droogmans, L. et al

in Journal of Virology (1996), 70(4),

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See detailFoaming Properties Of Surfactin, A Lipopeptide Biosurfactant From Bacillus Subtilis
Razafindralambo, Hary ULg; Paquot, Michel ULg; Baniel, Alain et al

in Journal of the American Oil Chemists' Society (1996), 73(1), 149-151

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam ... [more ▼]

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam volume and the liquid in the foam was monitored with optical and conductimetric methods to characterize foam formation and stability. Excellent foaming properties of surfactin were shown by its higher ability to form and stabilize the foam at a concentration as low as 0.05 mg/mL, in comparison with SDS and BSA. Surfactin produced a foam with intermediate maximum density and stabilized the liquid in foam, as well as BSA. [less ▲]

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See detailActeurs sociaux et perspectives préventives du hooliganisme: Orientations en guise de conclusions
Kellens, Georges ULg; Comeron, Manuel ULg

in Revue Sport (1996), 1(153), 63-64

Euro 2000: sécurité, stewards, Fan coaching

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See detailThe equatorial boundary of the ultraviolet Jovian north aurora observed with multispectral Hubble Space Telescope images
Grodent, Denis ULg; Dols, V.; Gérard, Jean-Claude ULg et al

in Journal of Geophysical Research (1996), 101(E1), 2163-2168

Multispectral observations of the far ultraviolet Jovian aurora with the faint object camera (FOC) on board the Hubble Space Telescope are reported. They are used to describe and compare the morphology ... [more ▼]

Multispectral observations of the far ultraviolet Jovian aurora with the faint object camera (FOC) on board the Hubble Space Telescope are reported. They are used to describe and compare the morphology and the mean brightness of the H-2 Lyman and Werner bands observed at 153, 125, and 130 nm. It is shown that most of the emissions are confined inside the 6 R(J) O-6-GSFC auroral oval and fill a large fraction of the polar cap. During the similar to 50 hours time span of the observations following a very strong aurora, no bright are was observed along the oval mapping the 30 R(J) O-6 oval. Hydrogen emissions at 125 and 130 nm are observed down to 50 degrees N and somewhat below, a region not accessible to previous FOC observations at longer wavelengths. Temporal variations are also observed on timescales of hours to days. [less ▲]

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See detailArthrite septique du boulet : corrélation entre imagerie et examen anatomo-pathologique
Busoni, Valeria ULg; Rossi, Giacomo; Denoix, Jean-Marie

in Pratique Vétérinaire Equine (1996), 28

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See detailA Non-Cofactor Role of Thiamine Derivatives in Excitable Cells?
Bettendorff, Lucien ULg

in Archives of Physiology & Biochemistry (1996), 104(6), 745-751

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain ... [more ▼]

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain lesions due to impaired oxidative metabolism. A specific non-cofactor role for thiamine has also been proposed in excitable cells and thiamine triphosphate (TTP) might be involved in the regulation of ion channels. Thiamine is taken up by neuroblastoma cells through a high affinity transporter. Inside the cells, it is rapidly phosphorylated to TDP. This high turnover TDP pool is the precursor for TTP. Most of the TDP however has a low turnover and is associated with PDH and KGDH in mitochondria. In excised inside-out patches from neuroblastoma cells, TTP, at a concentration of 1 microM, activates chloride channels of large unitary conductance, the so-called maxi-Cl- channels. These channels are inhibited by oxythiamine from the outide. In addition to the role of TTP in the regulation of chloride channels, thiamine itself, or a presently unknown analog, may have trophic effects on neuronal cells. [less ▲]

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See detailRole of pulmonary input impedance in right ventricular failure during experimental septic shock
D'Orio, Vincenzo ULg; LAMBERMONT, Bernard ULg; DETRY, Olivier ULg et al

in American Journal of Respiratory & Critical Care Medicine (1996), 2

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See detailThe Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock
Georges, Michel ULg; Cockett, N.

in Reproduction Nutrition Development (1996), 36(6), 651-7

An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge ... [more ▼]

An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge phenotype is characterized by a non-Mendelian inheritance pattern, referred to as polar overdominance, in which only heterozygous individuals having inherited the CLPG mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged. [less ▲]

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See detailDe Bruxelles à la ferme : agriculture et environnement en Belgique
Mormont, Marc ULg

in Etudes Rurales (1996), (No. 141/142), 157-169

The implementation of environmental protection policies in Flanders and Wallonia (Belgium) is investigated, looking at the stages of application and the roles of the actors involved. The factors which ... [more ▼]

The implementation of environmental protection policies in Flanders and Wallonia (Belgium) is investigated, looking at the stages of application and the roles of the actors involved. The factors which intervene in the implementation of a European policy, whose characteristics include reformulation at local level, are identified. Structural and political factors affecting change in agricultural and environmental policies are outlined, including regionalization and the division of responsibilities. The example of Belgium shows how it is important that each authority can redefine its own interests in defending the environment using its own resources and contacts. Implementation at local level implies a series of re-interpretations of each agri-environmental measure in the light of expectations and the reactions of land-users. [less ▲]

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See detailVoltage stability analysis in transient and mid-term time scales
Van Cutsem, Thierry ULg; Vournas, Costas

in IEEE Transactions on Power Systems (1996), 11

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See detailLe juste entre l’universel et le contextuel. Le débat anglo-saxon contemporain et son apport pour une approche socio-anthropologique du sens ordinaire de la justice dans un pays de tradition arabo-islamique
Nachi, Mohamed ULg

in Social Science Information/Information sur les sciences sociales (1996), 35(2), 389-425

Le présent article met en évidence les pertinences de l'idée d'un recours à la pensée philosophique pour mieux asseoir une approche socio-anthropologique du sens ordinaire de la justice. Pour se faire, l ... [more ▼]

Le présent article met en évidence les pertinences de l'idée d'un recours à la pensée philosophique pour mieux asseoir une approche socio-anthropologique du sens ordinaire de la justice. Pour se faire, l'auteur se propose d'analyser les présupposés épistémologiques et théoriques des trois courants philosophiques anglo-saxons qui placent au centre de leurs réflexions la question de la justice. Il montre, ce faisant, les limites de la thèse "libérale" et les apports respectifs des thèses marxienne et communautarienne. Certaines positions théoriques d'auteurs dits communautariens se révèlent plus pertinentes dans la mesure où elles permettent de situer la question de la justice à l'intérieur d'une tradition et de lui conférer un contenu socio-historique. Elles débouchent, de ce fait, sur une conception pluraliste de la justice qui permet de prendre en compte les données empiriques propres à une société de tradition arabo-islamique. [less ▲]

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See detailIntérêt de l'acide rétinoïque "tous trans" dans le traitement de la leucémie aiguë promyélocytaire
Hermanne, J.-P.; Tassin, F.; Bours, Vincent ULg et al

in Médecine et Hygiène (1996), 54

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See detailTwo rare European Ephemerum species (Bryophita): E. cohaerens rediscovered near Strasbourg (France) and E. stellatum new to Belgium
Vanderpoorten, Alain ULg; Stieperaere, H.; Klein, J.-P.

in Belgian Journal of Botany (1996), 129

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See detailNew Devonian fossil localities in Bolivia
Blieck, A; Gagnier, PY; Bigey, FP et al

in Journal of South American Earth Sciences (1996), 9(5-6), 295--308

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See detailBalancing the Cenozoic carbon and alkalinity cycles: Constraints from isotopic records
Godderis, Y.; François, Louis ULg

in Geophysical Research Letters (1996), 23(25), 3743-3746

A simple model of the carbon, alkalinity and strontium cycles is built up and used to interpret the carbon and strontium isotopic evolution of seawater over the Cenozoic as recorded in marine limestones ... [more ▼]

A simple model of the carbon, alkalinity and strontium cycles is built up and used to interpret the carbon and strontium isotopic evolution of seawater over the Cenozoic as recorded in marine limestones. The idea that weathering fluxes have increased globally over the Cenozoic in response to the Himalayan uplift is critically examined. It is shown that such an increase of global weathering, postulated to explain the sharp increase in the Sr-87/Sr-86 ratio, is not compatible with the carbon isotopic record, if the budgets of carbon, alkalinity and strontium are considered simultaneously. Another scenario of the Cenozoic evolution of global weathering consistent with the carbon isotopic record is proposed in which the global weathering flux varies only slightly over the Cenozoic with a small increase between 15 Ma and the present. This second scenario appears more consistent with the reconstructed carbonate sedimentation rate and the evolution of the carbon isotopic fractionation in continental and oceanic environments. [less ▲]

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See detailDe la phrase au texte dans l'enseignement d'une langue étrangère
Defays, Jean-Marc ULg

in Dialogues et cultures (1996), 40

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See detailInteractions between acetylcholine and substance P effects on lung mechanics in the rabbit.
Delaunois, Annie ULg; Gustin, Pascal ULg; Segura, P. et al

in Fundamental & Clinical Pharmacology (1996), 10(3), 278-88

The pharmacological mechanisms involved in the acetylcholine (ACh)- and substance P (SP)-induced changes in pulmonary mechanics were studied in isolated perfused rabbit lungs. Tracheal pressure (Ptr) and ... [more ▼]

The pharmacological mechanisms involved in the acetylcholine (ACh)- and substance P (SP)-induced changes in pulmonary mechanics were studied in isolated perfused rabbit lungs. Tracheal pressure (Ptr) and airflow were measured by a Fleisch pneumotachograph and pressure transducers. Air volume, lung resistance (RL) and dynamic compliance (Cdyn) were calculated. ACh induced a dose-dependent increase in Ptr and RL, and a decrease in Cdyn. These effects were strongly prevented by atropine, and partly by SR140333, a neurokinin NK1 receptor antagonist; SR48968, a neurokinin NK2 receptor antagonist; indomethacin and antihistaminics. Ketanserin had no significant protective effect against ACh. SP also induced concentration-dependent increases in RL and decreases in Cdyn. SR140333 and atropine strongly inhibited the effects of SP, while ketanserin, SR48968, antihistaminics and indomethacin did not protect the lungs against this drug. 5-hydroxytryptamine induced no significant change in lung mechanic parameters. Cumulative concentrations of histamine increased RL and decreased Cdyn. We conclude that ACh-induced changes in lung resistance and compliance are in part mediated by a direct effect on airway smooth muscle and in part by the stimulation of C fibers, by the release of histamine from mast cells and by the synthesis of arachidonic acid metabolites. In turn, the effects of SP on lung mechanics are partly due to cholinergic activation. [less ▲]

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See detailDeffand, Marie de Vichy-Chamrond, marquise du
Tilkin, Françoise ULg

in Voir barré (1996), 12-13

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See detailDoes proliferation status predict radiation response in human tumors?
Coucke, Philippe ULg

in Radiotherapy & Oncology (1996), 40(Supp 1), 55

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See detailChanges in gene expression in the leaf of Lolium temulentum L. Ceres during the photoperiodic induction of flowering
Périlleux, Claire ULg; Ongena, Philippe; Bernier, Georges ULg

in Planta (1996), 200(1), 32-40

Unifoliated plants of Lolium temulentum L. Ceres were induced to flower by a unique 24-h long day (LD) consisting of the extension of the regular 8-h short day (SD) (400 µmol photons·m-2·s-1, fluorescence ... [more ▼]

Unifoliated plants of Lolium temulentum L. Ceres were induced to flower by a unique 24-h long day (LD) consisting of the extension of the regular 8-h short day (SD) (400 µmol photons·m-2·s-1, fluorescence + incandescence) with incandescence at 10–15 µmol photonsm -2·s-1. The polyadenylated-RNA complement of leaf blade tissues was analysed at 4-h intervals during the photoperiod extension in LD vs. SD, by using two-dimensional polyacrylamide gel electrophoresis to resolve in-vitro-translated products. Of the 991 spots that were analysed, none appeared or disappeared during the inductive cycle, i.e. no qualitative effect of floral induction was detected, at any time. Sixty-eight spots were found whose intensity was influenced by lengthening of the photoperiod; 50 of them, i.e. ca. 5 of the population analysed, were affected before the end of the extension period and were thus potentially related to floral induction. Many of these RNAs were not quantitatively constant during a 24-h cycle in SD. Seven of them oscillated according to the ‘light-on’ and the ‘light-off’ signals, among which three seemed to be controlled by phytochrome since their relative amount increased under the standard light conditions but decreased under incandescence even faster than in darkness. The large majority of other RNAs varied with a timing that was not clearly driven by the alternation of light and darkness, indicating that genes related to the biological clock may be especially sensitive to the lengthening of the photoperiod. Furthermore, seven spots were observed that underwent a phase-shift in LD, which consisted, for six of them, of a phase advance of 4–8 h. The steady-state level of CAB mRNA was analysed because the CAB gene family (encoding the chlorophyll a/b-binding proteins of the light-harvesting complexes) is known to be controlled both by the biological clock and phytochrome. In SD, the level was high in the light and low in darkness; the fluctuation was conducted by a circadian rhythm. When plants were exposed to the inductive LD, the peak of mRNA accumulation that was expected according to the endogenous rhythmicity was abolished, possibly because of the change in light quality during the LD extension. [less ▲]

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See detailAntipeptide antibody against the bovine IGF-BP-2 : application to the detection of BST-treated cows
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Food & Agricultural Immunology (1996), 8

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See detailLes reliques sur ordinateur
George, Philippe ULg

in Le médiéviste et l'ordinateur (1996)

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See detailFoot: Quels supporters pour l'an 2000
Stassen, Benjamin; Comeron, Manuel ULg

in Revue Sport (1996), 1(153), 72

Football et hooliganisme: panorama européen, aspect sécuritaire et judiciaire, acteurs sociaux et perspectives préventives, Euro 2000: sécurité, stewards, fan coaching

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See detailLessons from the discovery of leptin: is obesity an endocrine disease?
Scheen, André ULg

in Acta Clinica Belgica (1996), 51(6), 371-6

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See detailAtomic data from the IRON Project. XIX. Radiative transition probabilities for forbidden lines in Fe II
Quinet, Pascal ULg; Le Dourneuf, M; Zeippen, C J

in Astronomy and Astrophysics. Supplement Series (1996), 120

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See detailCoulomb interaction and ferroelectric instability of BaTiO3
Ghosez, Philippe ULg; Gonze, X.; Michenaud, J. P.

in Europhysics Letters [=EPL] (1996), 33(9), 713-718

Using first-principles calculations, the phonon frequencies at the Gamma-point and the dielectric tensor are determined and analysed for the cubic and rhombohedral phases of BaTiO3. The dipole-dipole ... [more ▼]

Using first-principles calculations, the phonon frequencies at the Gamma-point and the dielectric tensor are determined and analysed for the cubic and rhombohedral phases of BaTiO3. The dipole-dipole interaction is then separated a la Cochran from the remaining short-range forces, in order to investigate their respective influence on lattice dynamics. This analysis highlights the delicate balance of forces leading to an unstable phonon in the cubic phase and demonstrates its extreme sensitivity to effective charge changes. Within our decomposition, the stabilization of the unstable mode in the rhombohedral phase or under isotropic pressure has a different origin. [less ▲]

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See detailHydrology and fluvial dynamics, in Geography Research in Belgium, Comité National de Géographie, DENIS J. (Ed.)
Petit, François ULg

in Bulletin de la Société Belge d'Etudes Géographiques = Tijdschrift van de Belgische Vereniging voor Aardrijkskundige Studies (1996)

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See detailComparaison des performances de porcs élevés sur litières ou sur caillebotis
Nicks, Baudouin ULg; Desiron, Alain; Canart, Bernard et al

in Annales de Médecine Vétérinaire (1996), 140

In a first experiment, performances and carcass quality of fattening pigs kept either on a litter with sawdust, on straw or on slatted floor were compared. Three batches of 17 pigs were kept on each floor ... [more ▼]

In a first experiment, performances and carcass quality of fattening pigs kept either on a litter with sawdust, on straw or on slatted floor were compared. Three batches of 17 pigs were kept on each floor type. Pens with litter were not cleaned until the end of the third fattening period. On average 100 kg of sawdust or 49 kg of straw were used per pig. The growth rate of pigs on litters was higher (P < 0,01) than that of pigs on slatted floor : 739 g/d on sawdust, 745 g/d on straw and 686 g/d on slatted floor. Carcass quality at slaughter was not different according to the floor type. The peak shear force of the M. Longissimus dorsi was higher for pigs kept on straw than for the 2 other groups. In a second experiment, 97 weaners, 4 weeks old, were divided in 3 groups on 3 floor types : a deep litter with sawdust, a deep litter with sawdust mixed with straw and a slatted floor. Between 4 and 10 weeks of age, the growth rates of pigs were different (P < 0,05) according to the 2 litters : 438 g/d on the deep litter with straw and sawdust, 397 g/d on sawdust and higher (P < 0,001) than that on slatted floor (273 g/d). Pigs on slatted floor were however disadvantaged by a lower health status in the breeding pig house. [less ▲]

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See detailDetection And Identification Of Sweet Potato Viruses By The Polymerase Chain Reaction
Colinet, D.; Lepoivre, Philippe ULg; Xia, Fz. et al

in Agro Food Industry Hi-Tech (1996), 7(2),

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See detailThiamine, Thiamine Phosphates, and Their Metabolizing Enzymes in Human Brain
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; Kish, Stephen J et al

in Journal of Neurochemistry (1996), 66(1), 250-8

Total thiamine (the sum of thiamine and its phosphate esters) concentrations are two- to fourfold lower in human brain than in the brain of other mammals. There were no differences in the total thiamine ... [more ▼]

Total thiamine (the sum of thiamine and its phosphate esters) concentrations are two- to fourfold lower in human brain than in the brain of other mammals. There were no differences in the total thiamine content between biopsied and autopsied human brain, except that in the latter, thiamine triphosphate was undetectable. The main thiamine phosphate-metabolizing enzymes could be detected in autopsied brain, and the kinetic parameters were comparable to those reported in other species. Thiamine diphosphate levels were lowest in hippocampus (15 +/- 4 pmol/mg of protein) and highest in mammillary bodies (24 +/- 4 pmol/mg of protein). Maximal levels of thiamine and its phosphate ester were found to be present at birth. In parietal cortex and globus pallidus, mean levels of total thiamine in the oldest age group (77-103 years) were, respectively, 21 and 26% lower than those in the middle age group (40-55 years). Unlike cerebral cortex, the globus pallidus showed a sharp drop in thiamine diphosphate levels during infancy, with concentrations in the oldest group being only approximately 50% of the levels present during the first 4 months of life. These data, consistent with previous observations conducted in blood, suggest a tendency toward decreased thiamine status in older people. [less ▲]

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See detailHigh prevalence of cardiovascular risk factors in children from the Belgian Luxembourg province. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in American Journal of Epidemiology (1996)

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See detailLa réforme du premier degré en Communauté française de Belgique veut relever le défi d'une pédagogie de la réussite
Beckers, Jacqueline ULg

in Recherche en Education. Théorie & Pratique (1996), 5-6

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See detailOverexpression of the 67-kD laminin receptor correlates with tumour progression in human colorectal carcinoma.
Sanjuan, X.; Fernandez, P. L.; Miquel, R. et al

in Journal of Pathology (The) (1996), 179(4), 376-80

The high affinity 67-kD laminin receptor (67LR) is a cell surface protein whose expression is increased in a number of human carcinoma models. To date, 67LR expression in colorectal carcinomas has been ... [more ▼]

The high affinity 67-kD laminin receptor (67LR) is a cell surface protein whose expression is increased in a number of human carcinoma models. To date, 67LR expression in colorectal carcinomas has been examined in a small number of cases. 67LR expression has been immunohistochemically analysed in a large series of human colorectal neoplasms, using the MLuC5 monoclonal antibody. The study included 59 samples of non-neoplastic mucosa, 45 polyps (11 hyperplastic, 34 adenomas), 196 carcinomas, and lymph node metastases of 87 carcinomas. Epithelial cells of normal mucosa and hyperplastic polyps were negative or showed weak positivity in the paranuclear and apical areas of the cytoplasm. In adenomas and carcinomas, the staining was stronger, with a membranous or cytoplasmic pattern. The expression of 67LR correlated significantly with the progression from normal mucosa (22 per cent) to adenoma (44 per cent), carcinoma (61 per cent), and lymph node metastasis (75 per cent) (P < 0.0001). Expression of the laminin receptor showed a tendency to be more frequently positive in advanced stage (III+IV; 67 (III+IV; 67 per cent) when compared with early stage (I+II) carcinomas (54 per cent). The difference, however, was not statistically significant (P = 0.058). In addition, 14 out of 28 (50 per cent) primary carcinomas without 67LR expression became positive in lymph node metastases, while most (86 per cent) of the MLuC5-positive primary carcinomas were also immunoreactive in metastases. In conclusion, these results indicate that 67LR is up-regulated in the progression of human colorectal carcinomas and may play a role in the local and metastatic progression of these tumours. [less ▲]

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See detailApproximation of reliability for multiple-trait animal models with missing data by canonical transformation
Gengler, Nicolas ULg; Misztal, I.

in Journal of Dairy Science (1996), 79(2), 317-328

An algorithm for approximation of reliability for multiple traits by multiple diagonalization was modified to support missing data by weighting transformed contributions of records based on the pattern of ... [more ▼]

An algorithm for approximation of reliability for multiple traits by multiple diagonalization was modified to support missing data by weighting transformed contributions of records based on the pattern of missing data. The accuracy of approximation was assessed with simulated and field data by comparing approximate reliabilities with those from direct inversion. Simulated data had several levels of missing data and covariances between traits; correlations were close to those for linear type traits of dairy cattle. Field data were 1) dairy records for milk, fat, and protein yields with 26% of the observations for fat and protein removed and 2) beef records for birth weight, weaning weight, and mean gain after weaning with 43% of observations missing. These files also contained empty fixed effect classes. The algorithm worked best for simulated data, and, when covariances between traits decreased, proportion of missing traits decreased and the number of empty fixed classes decreased. For dairy data, improvement over single-trait reliability occurred only for traits with missing data; for beef data, little or no improvement occurred. The method is useful with multiple diagonalization if the proportion of missing records or number of empty fixed effect classes or covariances between traits is moderate. [less ▲]

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See detailCellular and molecular mechanisms involved in thymic T-cell education to neuroendocrine self principles
Geenen, Vincent ULg; Benhida, Abdellah; Kecha, Ouafae et al

in International Journal of Thymology (1996), 4

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See detailEx-vivo cytokine production by whole blood cells from cancer patients
De Groote, Donat; Vrindts-Gevaert, Yvonne; Lopez Y Cadenas, Miguel ULg et al

in Cancer Detection & Prevention (1996), 20

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See detailPhotosensitized generation of hydroxyl radical by eught new sulfur and selenium analogs of psoralen
Collet, A.; Hoebeke, Maryse ULg; Piette, J. et al

in Journal of Photochemistry and Photobiology B : Biology (1996), 35

comparative study by ESR of the hydroxyl radical generation by 8 eight new sulfur and selenium analogs of psoralen

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See detailThe Coastal Ocean in a Global Change Perspective
Djenidi, Salim ULg

in Journal of Marine Systems (1996), 7(2-4), 117-118

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See detailProposition for the acylation mechanism of serine proteases: A one-step process?
Dive, Georges ULg; Dehareng, Dominique ULg; Peeters, Daniel

in International Journal of Quantum Chemistry (1996), 58(1), 85-107

This work proposes a very detailed ab initio study of the hypothesis for a one-step serine protease acylation process with one water molecule acting as the main catalyst reactant. For the 11 increasing ... [more ▼]

This work proposes a very detailed ab initio study of the hypothesis for a one-step serine protease acylation process with one water molecule acting as the main catalyst reactant. For the 11 increasing complexity models considered, the minimum and transition state conformations for the reaction are determined by full geometry optimizations at the ab initio self-consistent field (scF) levels within several basis sets, from MINI-1 to 6-31G, and, for the smallest complexes, at the post-SCF MP2 level within the 6-31G** basis set. The related thermodynamical quantities are calculated for all the conformations. The influence of the oxyanion hole stabilizer and of the dyad His57-Asp102 is quantified and a very good agreement is obtained with point mutagenesis. The activation barrier is found in the range 15-18 kcal/mol. (C) 1996 John Wiley & Sons, Inc. [less ▲]

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See detailMise au point relative à l'utilisation de la gonadolibérine en reproduction bovine. 2. Domaines d'application clinique.
Hanzen, Christian ULg; Houtain, Jean Yves; Laurent, Yves

in Médecin Vétérinaire du Québec (1996), 26(2), 47-54

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See detailThe seasonality of the CO2 exchange between the atmosphere and the land biosphere: A study with a global mechanistic vegetation model
Nemry, B.; François, Louis ULg; Warnant, Pierre ULg et al

in Journal of Geophysical Research (1996), 101(D3), 7111-7125

Two simulations of the seasonal variation of the global atmospheric CO2 distribution are obtained by combining an atmospheric transport model, two parameterizations of soil heterotrophic respiration (SHR ... [more ▼]

Two simulations of the seasonal variation of the global atmospheric CO2 distribution are obtained by combining an atmospheric transport model, two parameterizations of soil heterotrophic respiration (SHR), and a mechanistic model of carbon assimilation in the biosphere (CARAIB) that estimates the net primary production (NPP) of continental vegetation. The steady state hypothesis of the biosphere allows the spatial distribution and the global content of the soil carbon to be expressed as a function of the root fractions of soil respiration under forested and herbaceous vegetation covers. The sensitivity of the modeled CO2 signal to the wind field does not exceed the observed interannual variability. The influence of the various vegetation zones is quantified by the Fourier analysis of the modeled atmospheric signal. In the northern hemisphere, the temperate ecosystems dominate the seasonal atmospheric signal of the extratropical latitudes. The ecosystems of the tropical northern zone determine the local signal, while the southern tropical ecosystems influence largely the signal in the whole southern hemisphere. The results give credence to the mechanistic modeling of NPP since the simulated atmospheric signal is comparable with that obtained with normalized difference vegetation index (NDVI) based diagnostic models coupled with a parameterization of SHR fitted to optimize the atmospheric signal. [less ▲]

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See detailLa traversée des candiatures universitaires : Une analyse de cas
Beckers, Jacqueline ULg; Boxus, Elise ULg

in Res Academica (1996), 13(1-2), 85-104

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See detailThe degree/rapidity of the metabolic deterioration following interruption of a continuous subcutaneous insulin infusion is influenced by the prevailing blood glucose Level.
Castillo, M. J.; Scheen, André ULg; Lefebvre, Pierre ULg

in Journal of Clinical Endocrinology and Metabolism (1996), 81(5), 1975-8

This study aims at investigating the influence of the prevailing blood glucose level on the metabolic deterioration that follows a nocturnal interruption of a continuous sc insulin infusion (CSII ... [more ▼]

This study aims at investigating the influence of the prevailing blood glucose level on the metabolic deterioration that follows a nocturnal interruption of a continuous sc insulin infusion (CSII). Fifteen CSII-treated, C-peptide negative, diabetic patients have been studied CSII was interrupted from 2300 h to 0500 h. Blood was collected hourly from 2200 h to 0600 h. According to blood glucose (BG) levels at 2300 h, patients were classified as hypoglycemic (BG between 1.5 and 2.5 mmol/L, n = 5), normoglycemic (BG between 4.0 and 8.0 mmol/L, n = 5), or hyperglycemic (BG between 9.0 and 15.0 mmol/L, n = 5). At 2300 h, BG (mean +/- SEM) was 1.9 +/- 0.1, 6.2 +/- 0.7 and 11.2 +/- 1.0 mmol/L, respectively. After 6 h of CSII interruption, BG increased to 13.5 +/- 1.3, 14.1 +/- 1.2, and 19.4 +/- 1.2 mmol/L, respectively. At 2300 h, plasma 3-OH-butyrate levels were similar in the three groups (around 150 micromol/L). At 0500 h, significantly higher values were obtained for hyperglycemic (1460 +/- 127 micromol/L) than for normoglycemic (868 +/- 150 micromol/L) or hypoglycemic (837 +/- 80 micromol/L) patients. Enhanced lipolysis in initially hyperglycemic patients may contribute to accelerated ketogenesis and metabolic degradation. In conclusion, the metabolic deterioration that follows CSII interruption is influenced by the initial metabolic situation. Hypoglycemic patients deteriorate more rapidly, and hyperglycemic patients suffer a more important degradation. The latter are prone to rapid ketoacidosis if accidental CSII interruption occurs. [less ▲]

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See detailLa titanite de Bastogne (Belgique) et les minéraux associés
Hatert, Frédéric ULg; Fransolet, André-Mathieu ULg; Houssa, Michel

in Bulletin de la Société Royale des Sciences de Liège (1996), 65(6), 387-397

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See detailRelationship of Plasma Lactate Production to Cortisol Release Following Completion of Different Types of Sporting Events in Horses
Desmecht, Daniel ULg; Linden, Annick ULg; Amory, Hélène ULg et al

in Veterinary Research Communications (1996), 20(4), 371-379

Fifty-eight healthy horses were studied during five sporting events of various intensities and durations, namely show-jumping (n = 6), cross-country in a three-day event (n = 30), trotting races (n = 7 ... [more ▼]

Fifty-eight healthy horses were studied during five sporting events of various intensities and durations, namely show-jumping (n = 6), cross-country in a three-day event (n = 30), trotting races (n = 7), galloping races (n = 7) and endurance rides (n = 8). Venous blood samples were collected at rest and immediately after exercise and analysed for plasma cortisol (CORT) and lactate (LA) levels. The experimental procedure was the same throughout the investigation so as to permit a reliable comparison between the five types of exercise. The type of event significantly affected both the resting (p < or = 0.05) and the post-exercise (p < or = 0.01) plasma CORT. The degree of exercise-induced hypercortisolaemia was related to both the intensity and the duration of exercise for all five sporting events, but the endurance ride induced the most and show-jumping the least serious post-exercise CORT changes. LA production was much more closely related to the intensity of the exercise than was CORT. It is concluded that simultaneous measurements of plasma CORT and LA levels may be useful to discriminate between different types of exercise, adjust training programmes, and improve our comprehension of the physiology of sport horses at exercise. [less ▲]

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See detailSound diffusion by a layout of parallel suspended absorbing baffles
Embrechts, Jean-Jacques ULg

in Acustica united with Acta acustica (1996), 82 Suppl. 1

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See detailLes Deux Gredins et l'Ange énonciateur
Defays, Jean-Marc ULg

in Alice (des littératures de jeunesse) (1996), 1

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See detailAssessment of nuclear totipotency of fetal bovine diploid germ cells by nuclear transfer.
Moens, A.; Chesne, P.; Delhaise, F. et al

in Theriogenology (1996), 46(5), 871-80

Nuclear transfer was used to study nuclear reprogramming of fetal diploid bovine germ cells collected at two stages of the fetal development. In the first case, germ cells of both sexes were collected ... [more ▼]

Nuclear transfer was used to study nuclear reprogramming of fetal diploid bovine germ cells collected at two stages of the fetal development. In the first case, germ cells of both sexes were collected during their period of intragonadal mitotic multiplication at 48 days post coitum (d.p.c.). In the second case, only male germ cells were collected after this period, between 105 and 185 d.p.c. Isolated germ cells were fused with enucleated oocytes. Reconstituted embryos were cultured in vitro and those reaching the compacted morula or blastocyst stage were transferred into synchronous recipient heifers. Of 511 reconstituted embryos with 48 d.p.c. germ cells (309 males and 202 females), 48% (247/511 ) cleaved; 2.7% (14/511 ) reached the compacted morula stage and 8 of them the blastocyst stage (1.6%). No difference was observed between sexes. All 14 compacted morulae/blastocysts were transferred into 6 recipients and one pregnancy was initiated. This recipient was slaughtered at Day 35 and an abnormal conceptus (extended trophectoderm and degenerated embryo) was collected. Its male sex, genetically determined, corresponded to that of donor fetus. Of 380 reconstituted embryos with male 105 to 185 d.p.c. germ cells, 72.1% (274/380 ) cleaved, 2.1% (8 380 ) reached the compact morula stage and 7 of these the blastocyst stage (1.8%). Three blastocysts and one morula were transferred into 4 recipients. Two became pregnant at Day 21 but only one at Day 35 which aborted around Day 40. Our results show that the nucleus of diploid bovine germ cells of both sexes can be reprogrammed. However, in the absence of further development of these reconstituted embryos, nuclear totipotency of bovine diploid germ cells remains to be evidenced. [less ▲]

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See detailAnaesthesia for cardiac surgery
Larbuisson, Robert ULg; Lamy, Maurice ULg

in Current Opinion in Anaesthesiology (1996), 9

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See detailSuppression of Voluntary Temporalis Muscle Activity by Peripheral Limb Stimulations in Healthy Volunteers, Migraineurs and Tension-Type Headache Sufferes
Wang, W.; Schoenen, Jean ULg

in Functional Neurology (1996), 11(6, Nov-Dec), 307-15

We studied the inhibition of voluntary temporalis muscle activity after stimulations of extracephalic cutaneous or mixed nerves in 23 healthy volunteers, 29 patients suffering from migraine without aura ... [more ▼]

We studied the inhibition of voluntary temporalis muscle activity after stimulations of extracephalic cutaneous or mixed nerves in 23 healthy volunteers, 29 patients suffering from migraine without aura, 24 from episodic and 42 from chronic tension-type headache. Two successive EMG suppressions were induced bilaterally after stimulating at 40 mA the index finger or the median nerve, but not after stimulations of the sural or peroneal nerves. They differed from those obtained after labial commissure stimulation at 20 mA, i.e. the classic temporalis silent periods ES1 and ES2. Overall prevalence of index- (3%) and median nerve-induced (16%) early suppression was much lower than that of labial-induced ES1 (100%); prevalence of index-induced late suppression (index-"ES2") was 62% and that of median-"ES2" 48%, compared with 97% for labial-ES2. Latency and duration of index-/median-"ES2" were not significantly different between groups. Index-"ES2" occurred significantly more often in migraineurs (83%) than in controls (48%) suggesting that the spino-bulbar pathways involved in index-/median-"ES2" are hyperexcitable in migraine. [less ▲]

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See detailCombined Liver - Spleen -small intestine grafting in a rat model: Role of transplanting additional lymphoid tissue on survival.
D'Silva, Milbhor; Pirenne, Jacques; Nakhleh, R. E. et al

in International Surgery (1996), (81), 109-114

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See detailRuminal, cardiorespiratory and adrenocortical sequelae of Na2EDTA-induced hypocalcemia in calves
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in Veterinary Research Communications (1996), 20

A study was undertaken to provide further information on the ruminal, cardiorespiratory and hypothalamo-pituitary-adrenocortical (HPAC) physiological sequelae of hypocalcaemia in dairy calves. The ... [more ▼]

A study was undertaken to provide further information on the ruminal, cardiorespiratory and hypothalamo-pituitary-adrenocortical (HPAC) physiological sequelae of hypocalcaemia in dairy calves. The functional picture observed in standing calves experiencing Na2EDTA-induced progressive hypocalcaemia showed a biphasic pattern. During the first phase (Ca2+ varying between 1.20 +/- 0.09 and 0.64 +/- 0.15 mmol/L, mean +/- SD), the animals became dull and lethargic, shifting their weight from one hind limb to the other, with cool extremities and hypersalivation. Their ventilation was slightly increased but their heart rate, thoracoabdominal pressure, pulmonary mechanics, haemoglobin and temperature remained constant. Conversely, their systemic arterial pressure (SAP) and the amplitude of their ruminal contractions (RCA) were severely decreased. During the second phase (Ca2+ < 0.64 +/- 0.15 mmol/L), there was restlessness, tachycardia, hypertension, polycythaemia and, finally, inability to stay upright. It is suggested that the diminished Ca2+ availability caused smooth-muscle and myocardial dysfunctions which could explain the RCA and SAP changes recorded during the first phase, whereas neural and/or humoral sympathetic discharge probably accounted for the reversal in SAP and heart rate when Ca2+ was decreased further. Serum cortisol increased regularly and remained significantly correlated with Ca2+ in each animal. Moreover, regression of delta cortisol/delta Ca2+ on delta Ca2+/delta Na2EDTA was significant (p < or = 0.001). It was concluded that mild asymptomatic hypocalcaemia severely impairs ruminal function, which will progressively worsen the Ca2+ deficit; that the inability to maintain posture in hypocalcaemia is not due to hypotension; and that the higher the HPAC response to hypocalcaemia, the higher the resistance to its effects. An asymptomatic periparturient cow with barely detectable ruminal activity may merit preventive calcium borogluconate therapy. Also, the physiological role of hypotension in explaining the clinical picture may be less important than other processes, such as neuromuscular failure. Finally, the present results imply a possible HPAC exhaustion in cows with periparturient paretic hypocalcaemia [less ▲]

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See detailPhénologie et domaine vital de la salamandre terrestre Salamandra salamandra terrestris (Amphibia, Caudata) dans un bois du Pays de Herve (Belgique)
Denoël, Mathieu ULg

in Cahiers d'Ethologie (1996), 16

The aim of this study was to approach some aspects of the life-history of the fire salamander Salamandra s. terrestris in a small wood of the Vesdre Valley (Liege Province, Belgium). In 1996, 189 ... [more ▼]

The aim of this study was to approach some aspects of the life-history of the fire salamander Salamandra s. terrestris in a small wood of the Vesdre Valley (Liege Province, Belgium). In 1996, 189 salamanders were marked and 68 recaptured. Their cartographic position and the meteorological conditions were noted. Salamanders were active from March to October, mated from May to August and females gave birth to larvae in March-April. Only a small part of the population was active at the same moment. Salamanders were generally faithful to a home range, in spite of some erratic individuals, and are apparently non-territorial. They moved principally along a path. The population is important but strongly threatened by the perturbation of its environment: stream drying, clearing and forest fire. [less ▲]

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See detailA computer controlled PIGE setup for the analysis of thin samples
Strivay, David ULg; Garnir, Henri-Pierre ULg; Weber, Georges

in Nuclear Instruments & Methods in Physics Research Section B (1996), 113(1-4), 407-410

A computer controlled PIGE setup has been improved by adding a beam energy disperser which whips out most of the structure of the proton excitation functions and allows better analysis of thin samples.

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See detailDéveloppement actuel du concept de l'hygiène en agro-alimentaire et des exigences des normes européennes.
Vindevogel, Henri ULg; Daube, Georges ULg; Hans, J. C. et al

in Annales de Médecine Vétérinaire (1996), 140

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See detailL'Aurignacien de Siuren I (Crimée, Ukraine)
Otte, Marcel ULg; Noiret, Pierre ULg; Tatartsev, Serguei et al

in Anthropologica et Praehistorica : Bulletin de la Société Royale Belge d'Anthropologie et de Préhistoire (1996), 107

New excavations at Siuren I allowed to control the stratigraphy of the site, to give radiometric dating to the two main layers encountered and to reevaluate the lithic and faunal materials. The new dates ... [more ▼]

New excavations at Siuren I allowed to control the stratigraphy of the site, to give radiometric dating to the two main layers encountered and to reevaluate the lithic and faunal materials. The new dates show that a real Aurignacian is present at Siuren I around 28000-29000 BP. These occupations were probably a late extension of this culture through Eastern Europe. [less ▲]

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See detailThe influence of follicular dendritic cells on B-cell proliferation depends on the activation of B cells and the mitogen used.
Bosseloir, A.; Bouzahzah, F.; Defrance, T. H. et al

in Scandinavian Journal of Immunology (1996), 43(1), 23-30

Follicular dendritic cells (FDC) are unique non-lymphoid cells found only in lymph follicles. They play a part in the survival, proliferation and differentiation of B cells. To analyse the influence of ... [more ▼]

Follicular dendritic cells (FDC) are unique non-lymphoid cells found only in lymph follicles. They play a part in the survival, proliferation and differentiation of B cells. To analyse the influence of FDC on B-lymphocyte proliferation, we isolated them from human tonsils on albumin gradients and treated them with mitomycin C to prevent the multiplication of lymphoid cells harboured in their cytoplasmic evaginations. FDC cultured for 12-16 h remained attached to the substrate; non-adherent cells were carefully eliminated by washing. Purified B cells cultured alone or with contaminant-cleared FDC were maintained for 2 days in the presence or absence of various stimulants, after which tritiated thymidine uptake by these cells was measured. In the absence of activators, FDC did not induce B-cell multiplication. B cells cultured in the presence of FDC exhibited increased 3H-TdR uptake when activated with anti-CD40 MoAb, anti-immunoglobulin MoAb or transferrin, but not when stimulated with Staphylococcus aureus strain Cowan I (SAC) at a given concentration. In the latter case, B-cell proliferation clearly decreased. In control cocultures where mitomycin-C-treated non-adherent cells were used instead of FDC in the presence of the different stimulants, no increase in B-cell proliferation was observed. The results suggest that, inside the germinal centres, FDC modulation of B-cell proliferation depends on the activation state of the B cells and on the stimulant encountered. [less ▲]

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See detailHomogeneous Lyapunov Functions and Necessary Conditions for Stabilization
Sepulchre, Rodolphe ULg; Aeyels, D.

in Journal of mathematics for control, signal and systems (1996), 9(1), 34-58

We provide necessary conditions for the stabilization of nonlinear control systems with the additional requirement that a time-invariant homogeneous Lyapunov function exists for the closed-loop system.

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See detailVariations autour de la définition des fonctions convexes
Bair, Jacques ULg; Haesbroeck, Gentiane ULg

in Mathématique et Pédagogie (1996), 105

Dans le cadre des fonctions réelles, le concept de convexité est présenté dans divers registres sémiotiques, analytiques ou graphiques.

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See detailQuel encadrement pour quelle qualité de l'enseignement?
Lafontaine, Dominique ULg

in Pilotinfo (1996), (13), 1-8

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