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See detailVascular factors in the pathogenesis of pre-eclampsia: recent findings
Foidart, Jean-Michel ULg; Lambotte, R.

in Revue Française de Gynécologie et d'Obstétrique (1984), 79(4), 249-252

Normal, rigid and fibrotic utero-placental arteries are resistant to the action of circulating vaso-motor substances. In contrast, the persistence and the hyperplasia of smooth muscle fibres result in a ... [more ▼]

Normal, rigid and fibrotic utero-placental arteries are resistant to the action of circulating vaso-motor substances. In contrast, the persistence and the hyperplasia of smooth muscle fibres result in a reduced flow in the intervillous compartment and a sensitivity of the vessels to vaso-constrictor substances. These lesions, which develop after the twentieth week, provide the necessary conditions for the subsequent development of the characteristic vicious cycles of eclampsia. [less ▲]

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See detailReversed-phase separation of tetrodotoxin and its oxidized derivative at C11-position detected spectrophotometrically at 195 nm
Bontemps, J; Grandfils, Christian ULg; Dandrifosse, Guy ULg et al

in HRC & CC. Journal of High Resolution Chromatography & Chromatography Communications (1984), 7

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See detailOn the structural analogy between D-alanyl-D-alanine terminated peptides and beta-lactam antibiotics
Brasseur, Josette ULg; Dive, Georges ULg; Ghuysen, Jean-Marie ULg

in European Journal of Medicinal Chemistry (1984), 4

Structural analogy between D-alanyl-D-alanine terminated peptides (and analogues) of varying substrate activity toward D-alanyl-D-alanine-cleaving peptidases, and bicyclic fused ring azetidinone ... [more ▼]

Structural analogy between D-alanyl-D-alanine terminated peptides (and analogues) of varying substrate activity toward D-alanyl-D-alanine-cleaving peptidases, and bicyclic fused ring azetidinone structures of varying inactivating potency toward the same enzymes has been exa-mihed by comparing the relative spatial disposition of the carboxylate function at the C-terminal position and the amide function at the N-terminal position with respect to the scissile amide bond at the central position. The observed variations in the geometric parameters and the molecular electrostatic potential maps generated by these functional groups suggest multiple modes of binding. In the monobactam sulfazecin, the relative disposition of at least the scissile amide bond and the terminal sulphamate group is comparable to that of the corresponding functions in the bicyclic β-lactams. [less ▲]

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See detailInterim results on the clinical effects of i.v. administered thymopentin in active rheumatoid arthritis
Malaise, Michel ULg; Franchimont, P.; Hauwaert, Christian ULg et al

in International Journal of Clinical Pharmacology, Therapy and Toxicology (1984), 4(6), 451-457

Forty-one patients with active rheumatoid arthritis entered a controlled, double-blind, randomized study; 21 received prolonged i.v. injections (10 min) of thymopentin 50 mg 3 times a week for 3 ... [more ▼]

Forty-one patients with active rheumatoid arthritis entered a controlled, double-blind, randomized study; 21 received prolonged i.v. injections (10 min) of thymopentin 50 mg 3 times a week for 3 consecutive weeks; the other 20 received placebo under the same conditions. The groups were comparable at the start of the study. Statistical tests of changes within the treatment groups after 3 weeks showed that the improvement achieved in the thymopentin group was significant (p less than 0.05 or p less than 0.01) for each clinical parameter, except for left-hand grip strength. On the other hand, no significant improvement was observed for any parameter except morning stiffness in the patients on placebo. The intergroup comparison showed significant differences, favouring thymopentin over placebo treatment, in the Ritchie index, scores for swollen joints, assessment of severity of pain and scores for changes in the activity of the disease. Only minor side-effects were experienced in the two treatment groups. The present placebo-controlled double-blind study confirms the previous positive results achieved in open studies, i.e., the beneficial therapeutic effect of prolonged i.v. injections of thymopentin in patients with severe rheumatoid arthritis observed after 3 weeks of therapy. The drug appears to be safe at the dose regimen used. [less ▲]

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See detailUnimolecular Decay Paths of Electronically Excited Species. V. The A2B1 State of H2CO+
Barbier, Christian ULg; Galloy, Claudine; Lorquet, Jean-Claude ULg

in Journal of Chemical Physics (1984), 81

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See detailExigences climatiques et modes de logement des veaux d'élevage
Dechamps, P.; Nicks, Baudouin ULg

in Annales de Médecine Vétérinaire (1984), 128

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See detailExpression of different regional patterns of fibronectin immunoreactivity during mesoblast formation in the chick blastoderm
Harrisson, F.; Vanroelen, Ch; Foidart, Jean-Michel ULg et al

in Developmental Biology (1984), 101(2), 373-381

The appearance and distribution of the extracellular material glycoprotein, fibronectin, was investigated in gastrulating chick embryos using affinity-purified anti-human plasma fibronectin antibodies ... [more ▼]

The appearance and distribution of the extracellular material glycoprotein, fibronectin, was investigated in gastrulating chick embryos using affinity-purified anti-human plasma fibronectin antibodies. Preservation of tissue structure and immunoreactivity was carried out by ethanol/acetic acid fixation or by formaldehyde/glutaraldehyde fixation. Using the former fixation method, fibronectin immunoreactivity was detected (1) at the ventral surface of the upper layer or epiblast, mainly anterior and lateral to Hensen's node, in regions where middle-layer or mesoblast cells are not yet present, and (2) sparsely in extracellular spaces of the deep layer. Using the latter fixation method, fibronectin immunoreactivity was, moreover, found at the entire ventral surface of the upper layer, i.e., also at the epithelial-mesenchymal interface, where a basement membrane was previously described. At the light microscope level, we could not detect significant immunoreactivity in the middle layer. Treatment of sections of ethanol-fixed blastoderms with testicular hyaluronidase before immunostaining for fibronectin partially demasked the antigenic sites of this glycoprotein at the epithelial-mesenchymal interface. The present report indicates that the different regional patterns of fibronectin immunoreactivity in the basement membrane of the upper layer are spatially and temporally correlated with migration and positioning of mesoblast cells. These regional patterns are probably due to differences in the composition of fibronectin-associated material such as chondroitin sulfate A and/or C proteoglycans, and/or hyaluronate, before and after mesoblast expansion, rather than to differences in the distribution of fibronectin itself. In this respect, it is noteworthy that the chemical composition of the basement membrane of an epithelium changes as mesenchyme cells migrate over it. The results also favor the idea that fibronectin is a structural component of the whole basement membrane which is used as a substrate for migration of mesenchymal cells. [less ▲]

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See detailTexture of manganese nodules used as a catalyst for demetalizing and desulfurizing petroleum residua
Dodet, Claude ULg; Noville, Francis ULg; Crine, Michel ULg et al

in Colloids and Surfaces A : Physicochemical and Engineering Aspects (1984), 11

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See detailCellular proliferation in villi of normal and pathological pregnancies.
Hustin, J.; Foidart, Jean-Michel ULg; Lambotte, R.

in Gynecologic & Obstetric Investigation (1984), 17(1), 1-9

DNA and protein synthesis have been studied in placental villi from normal and pathological cases by in vitro incorporation of tritiated thymidine or tritiated proline and subsequent counting or ... [more ▼]

DNA and protein synthesis have been studied in placental villi from normal and pathological cases by in vitro incorporation of tritiated thymidine or tritiated proline and subsequent counting or autoradiography. It appeared that cytotrophoblastic DNA synthesis continued until term and that it was particularly important in preeclampsia cases and in cases of villous immaturity (rhesus sensitization). Protein synthesis was also increased in preeclampsia and seemed to be due to a very active cytotrophoblastic metabolism. The most interesting finding was that in preeclampsia cases, especially when intrauterine growth retardation was superimposed, villous capillary endothelial cell proliferation was as prominent as in cases where villous maturation was not achieved. Such results are highly suggestive of an important compensatory proliferative mechanism in the placentae of preeclamptic women. [less ▲]

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See detailUn logiciel de cartographie assistée par micro-ordinateur
Donnay, Jean-Paul ULg

in Cartographica (1984), 21(2 & 3), 93-100

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See detailPrecision and practicability: on the definition of the Devonian-Carboniferous Boundary.
Paproth, E; Streel, Maurice ULg

in Courier Forschungsinstitut Senckenberg (1984), 67

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See detaila prospective study of intrapulmonary fat accumulation in the newborn lung following intralipid infusion
Battisti, Oreste ULg; Levene, M. I.; Wigglesworth, J. S. et al

in Acta Paediatrica Scandinavica (1984), 73

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See detailEvolution diurne des profils thermiques inversifs les plus courants observés le long de la tour du Bol d'Air au SSW de Liège
Grilli-Delrez, A.; Erpicum, Michel ULg

in Bulletin de la Société Géographique de Liège (1984), 20

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See detailCaractérisation d'Escherichia coli entérotoxinogène d'origine bovine par hybridation ADN-ADN sur colonies
Mainil, Jacques ULg; Bex, F.; Couturier, M. et al

in Annales de Recherches Vétérinaires = Annals of Veterinary Research (1984), 128

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See detailPrecise localization of antigens on follicular dendritic cells.
Radoux, D.; Heinen, Ernst ULg; Kinet-Denoel, C. et al

in Cell & Tissue Research (1984), 235(2), 267-74

Horse-spleen ferritin or bovine serum albumin conjugated to colloidal gold (BSA-gold) were injected subcutaneously in preimmunized mice. In draining lymph nodes both antigens were located in macrophages ... [more ▼]

Horse-spleen ferritin or bovine serum albumin conjugated to colloidal gold (BSA-gold) were injected subcutaneously in preimmunized mice. In draining lymph nodes both antigens were located in macrophages or between the cytoplasmic processes of follicular dendritic cells (FDC). Some of the antigens remained trapped on FDC until day 31 after injection. Simultaneous injection of both antigens showed that they were located between the infoldings of the same FDC. These cells are thus able to retain at least two different antigens on their surface. The peculiar arrangement of ferritin between the cytoplasmic infoldings suggests that this antigen is fixed on both cell membranes by specific antibodies. The trapped immune complexes could thus stabilize the FDC membrane system. The antigen retention requires the presence of specific antibodies since BSA-gold or ferritin injected without preimmunization were not found between FDC processes. Nonantigenic materials, such as colloidal gold or carbon particles, are not trapped by FDC, except when injected in large amounts. The antigens were trapped on the surface of FDC, however unfrequently in close contact with lymphocytes. FDC might protect lymphocytes against an excess of immune complexes and act as regulators of contacts between lymphocytes and immune complexes. [less ▲]

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See detailEssai synécologique sur les micromammifères d'Europe atlantique et ouest méditerranéenne: étude par analyse du régime alimentaire de Tyto alba (Scopoli)
Libois, Roland ULg

in Cahiers d'Ethologie (1984), 4(2), 1-202

Methods: owl pellets in Belgium, Corsica and in East Pyrenees. Quality of the samples: exhaustivity and representativity. Habitat evaluation in the barn owl home range: climate, orography, vegetation ... [more ▼]

Methods: owl pellets in Belgium, Corsica and in East Pyrenees. Quality of the samples: exhaustivity and representativity. Habitat evaluation in the barn owl home range: climate, orography, vegetation. Discussion for the method. Landscape structure and the mammal communities. Interspecific competition in island biocoenoses. [less ▲]

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See detailNatural infection of Swiss mice by the Mouse Mammary Tumor Virus (MMTV). 2. Studies on the pathway of infection
Hainaut, P.; Vaira, Dolorès ULg; Calberg-Bacq, Claire Michelle et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1984), 92(1), 28

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See detailGlipizide increases plasma insulin but not C-peptide level after a standardized breakfast in type 2 diabetic patients.
Scheen, André ULg; Lefebvre, Pierre ULg; Luyckx, A. S.

in European Journal of Clinical Pharmacology (1984), 26(4), 471-4

Peripheral blood glucose, plasma insulin and C-peptide levels were investigated after giving a standardized breakfast (500 kcal, 60 g carbohydrates) to 10 nonobese Type 2 diabetic patients previously ... [more ▼]

Peripheral blood glucose, plasma insulin and C-peptide levels were investigated after giving a standardized breakfast (500 kcal, 60 g carbohydrates) to 10 nonobese Type 2 diabetic patients previously treated by diet alone. Each patient received at random, at 1 week intervals, either 5 mg glipizide (meal + glipizide) or a placebo (meal alone) 30 min before breakfast. Basal values of blood glucose, plasma insulin and C-peptide were similar on both occasions. After meal + glipizide, the blood glucose increase was sharply limited whereas the rise in plasma insulin was steeper and reached twice as high a level. In contrast, the rise in plasma C-peptide was similar in both conditions. Consequently, the areas under the curves (0-300 min) showed a marked reduction in blood glucose after meal + glipizide (2289 +/- 149 versus 3101 +/- 169 mmol X min/1; 2p less than 0.001), associated with a significant increase in plasma insulin (14219 +/- 3261 versus 7591 +/- 1173 microU X min/ml; 2p less than 0.025) but no significant change in plasma C-peptide (342 +/- 45 versus 326 +/- 34 pmol X min/ml; N.S.). The insulin/C-peptide molar ratio was thus significantly increased after meal + glipizide (0.41 +/- 0.06 versus 0.23 +/- 0.04 at the 60th min; 2p less than 0.02). The dissociation between the responses of insulin and C-peptide suggests that a single dose of 5 mg glipizide in Type 2 diabetic subjects may enhance availability of peripheral insulin by extrapancreatic mechanism(s). This phenomenon may result in a higher circulating level of the hormone and therefore represent a further mode of action of sulphonylureas.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailLa micro- et macroflore du Gedinnien de la Gileppe, synclinorium de la Vesdre, Belgique.
Steemans, Philippe ULg; Gerrienne, Philippe ULg

in Annales de la Société Géologique de Belgique (1984), 107

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See detailImprovement of pretreatments and technologies for enzymatic hydrolysis of cellulose from industrial and agricultural refuse and comparison with acidic hydrolysis.
Paquot, Michel ULg; Thonart, Philippe ULg; Foucart, M. et al

Scientific journal (1984)

Chemical and enzymatic hydrolysis of cellulose are compared. Basic research on paper mill celluloses shows that it is mainly the endo- and exocellulase activities which are absorbed on the substrate. In ... [more ▼]

Chemical and enzymatic hydrolysis of cellulose are compared. Basic research on paper mill celluloses shows that it is mainly the endo- and exocellulase activities which are absorbed on the substrate. In the case of the Trichoderma reesei complex with Aspergillus niger beta-glucosidase, the exocellulase activity has proved to be the limiting factor in the design of a reactor which recycles the enzyme complex. Tests were carried out on various pretreatments for substrates of more complex chemical composition, such as straw, maize stalks, beet pulp. The rate and overall degree of hydrolysis, especially for straw, were improved by chemical treatments in combination with mechanical processes. A first pilot plant for straw hydrolysis was set up with the aim of attaining high sugar concn in the fermenter. [less ▲]

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See detailEffect of DNA photosensitization mediated by promazine derivatives on transcription in vitro
Decuyper, J.; Piette, Jacques ULg; Rentier, Bernard ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1984), 92(2), 18

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See detailDiagnostic de la colibacillose entérotoxique du veau au moyen de deux sondes ST : application sur le contenu intestinal
Mainil, Jacques ULg; Bex, F.; Couturier, M. et al

in Annales de Médecine Vétérinaire (1984), 128

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See detailEtude des variations de quelques enzymes sériques lors de myopathie postanesthésique équine (M.P.A.E.)
Serteyn, Didier ULg; d'Ieteren, G.; Spyropoulos, E. et al

in Annales de Médecine Vétérinaire (1984), 128

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See detailA Dissociative Electroionization Study of Nitrous Oxide. The O+ and N+ Dissociation channels.
Olivier, J. L.; Locht, Robert ULg; Momigny, J.

in Chemical Physics (1984), 84

After the investigation of the decay of N2O into NO+ and N2+ the dissociation channels leading to O+ and N+ are examined by electroionization using ion kinetic energy and mass analysis. Appearance ... [more ▼]

After the investigation of the decay of N2O into NO+ and N2+ the dissociation channels leading to O+ and N+ are examined by electroionization using ion kinetic energy and mass analysis. Appearance energies of O+ and N+ are measured as a function of the kinetic energy of the fragment ions. Predissociation is the main mechanism for ion production in both channels. In the O+ decay channel the 4Sigma- state is an important intermediate. The neutral N2(X1Sigma+/g) mainly appears vibrationally excited. In the N+ dissociation channel, 2Pi states have to play an important role by predissociating the N2O(C2Sigma+) state and the higher-lying doubly excited states of N2O+. [less ▲]

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See detailL'art wallon en quête de légitimité
Duchesne, Jean-Patrick ULg

in Cahiers du C.A.C.E.F. (1984), 119

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See detailEfficacite contre de Ditylenchus dipsaci (Kuhn) Fil. De nematicides incorpores dans l'enrobage de graines de feverole (Vicia faba L.).
Schiffers, Bruno ULg; Fraselle, J.; Hubrecht, F. et al

in Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) (1984), 49(2b), 635-641

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See detailQuand les fantômes viennent à notre rencontre (à propos du gros plan)
Mélon, Marc-Emmanuel ULg

in Revue Belge du Cinéma (1984), 10(Hiver), 75-84

Le gros plan de visage comme image-pellicule.

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See detailUn médicinaire du XVe siècle (Warfusée)
Boutier, Marie-Guy ULg

in Dialectes de Wallonie (1984), 12

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See detailColour rendering and spectral power distribution: a new parametric approach
Embrechts, Jean-Jacques ULg

in Lighting Research & Technology (1984), 16 (3)

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See detailFetal calf serum-mediated inhibition of neurite growth from ciliary ganglion neurons in vitro
Davis, G. E.; Skaper, S. D.; Manthorpe, M. et al

in Journal of Neuroscience Research (1984), 12(1), 29-39

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See detailImmunohistochemical localization of basement membrane components and interstitial collagen types in preovulatory rat ovarian follicles.
Palotie, A.; Peltonen, L.; Foidart, Jean-Michel ULg et al

in Collagen and Related Research (1984), 4(4), 279-87

Cryosections of ovaries from rats treated with pregnant mare serum gonadotropin (PMSG) were immunostained with antibodies against collagen types, I, III, IV and V, laminin and heparan sulphate ... [more ▼]

Cryosections of ovaries from rats treated with pregnant mare serum gonadotropin (PMSG) were immunostained with antibodies against collagen types, I, III, IV and V, laminin and heparan sulphate proteoglycan using the peroxidase-antiperoxidase technique. A uniform belt-like staining was observed between the granulosa and theca interna layers with antibodies against type IV collagen, laminin and heparan sulphate proteoglycan. Interstitial collagens type I and III stained the connective tissue in the theca externa layer but gave only faint staining in the area between the granulosa and theca interna zones. If the PMSG-treated rats were injected with human chorionic gonadotropin the number of follicles that showed a discontinuous, ragged or disrupted staining reaction in the area between the granulosa and theca interna layers was clearly increased. Surprisingly in such cases also a punctate staining reaction was seen in the basal granulosa cells. When the rats were injected with radioactive human chorionic gonadotropin, most of the ovarian follicles were labeled within 2 hours. These follicles still showed a continuous staining reaction with antibodies against basement membrane components at the border of the granulosa and theca interna cell layers. These results suggest that there is a basement membrane-like structure in Graafian follicles between the granulosa cells and theca interna layer, and that this basement membrane is disrupted after human chorionic gonadotropin stimulation. [less ▲]

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See detailLes questions : quelles structures les enfants de 7 à 12 ans utilisent-ils ?
Lafontaine, Dominique ULg; Lardinois, B.

in Bulletin de Psychologie (1984), 368

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See detailParticular points of elastic analysis of clad pitched roof portal frame structures
Franssen, Jean-Marc ULg

in Thin-Walled Structures (1984), 2(2), 165-174

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See detailEnseignant et enseignement assisté par ordinateur
de Landsheere, Gilbert ULg

in Cahiers de Clio (1984), 80

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See detailParticular points of elastic analysis of clad pitched roof portal frame structures
Franssen, Jean-Marc ULg

in Thin-Walled Structures (1984), 2(2), 165-174

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See detailIconographies de saints mosans : Paris, B. Nat. et Bruxelles, B. R. Estampes:
George, Philippe ULg

in Bulletin de la Société Royale Le Vieux-Liège (1984)

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See detailModèles expérimentaux pour l'étude des infections virales du système nerveux
Rentier, Bernard ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1984), 139(3), 218-226

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See detailArchitecture du Proche Orient ancien et histoire de l'architecture
Tunca, Önhan ULg

in Art&Fact (1984)

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See detailIndirect Uv Detection of Hydrophilic Ionized Compounds in Reversed-Phase Liquid Chromatography by Use of a Uv-Absorbing Ion of the Same Charge
Crommen, Jacques ULg; Herné, Patrick ULg

in Journal of Pharmaceutical & Biomedical Analysis (1984), 2(2), 241-53

Ion-pair reversed-phase liquid chromatographic systems have been developed that allow the detection and quantitation of low amounts of hydrophilic ionized substances, which otherwise display little or no ... [more ▼]

Ion-pair reversed-phase liquid chromatographic systems have been developed that allow the detection and quantitation of low amounts of hydrophilic ionized substances, which otherwise display little or no capability for optical detection. The mobile phase contains a UV-absorbing ion of the same charge and hydrophobic character as the samples, most often together with a hydrophobic counter-ion to give the samples suitable retention; the stationary phase consists of octadecylsilica. Chromatograms featuring two system peaks are usually obtained, and these give rise to some deviations from the usual response pattern. In the present work the influence on retention and detection sensitivity of the non-absorbing counter-ion, the UV-absorbing ion and the uncharged organic modifier have been studied systematically. Principles for optimizing the detector response by changing the mobile phase composition have been deduced. Examples of applications of the indirect detection technique to the analysis of hydrophilic compounds of pharmaceutical and biological interest, such as amino acids, water-soluble vitamins and piperazine, are presented. [less ▲]

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See detailUse of the Polymer WSR 301 in Hydraulic Tests, Fundamentals and Applications of Polymer ; Drag Reduction in Liquid Flows
Marchal, Jean ULg; Lejeune, A.

in Proceed of the Third International Conference on Drag Reduction (1984)

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See detailIsolation of follicular dendritic cells from human tonsils and adenoids. I. Procedure and morphological characterization.
Lilet, C.; Radoux, D.; Heinen, Ernst ULg et al

in Journal of Immunological Methods (1984), 66(2), 235-44

Follicular dendritic cells have been isolated from human tonsils and adenoids and characterized at the ultrastructural level. Follicles were dissected and digested with different hydrolytic enzymes. The ... [more ▼]

Follicular dendritic cells have been isolated from human tonsils and adenoids and characterized at the ultrastructural level. Follicles were dissected and digested with different hydrolytic enzymes. The cells were separated by sedimentation at unit gravity. By this procedure we obtained follicular dendritic cells enveloping lymphocytes with their cytoplasmic extensions in a way analogous to that described for isolated thymic nurse cells. The ultrastructural features of isolated follicular dendritic cells are similar to those observed in situ. Prolonged enzymatic action caused loss of the enveloped lymphocytes. [less ▲]

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See detailMyofibrillar composition of some red- and white-blooded Antarctic teleosts
Feller, Georges ULg; Boinet, P.

in Molecular Physiology (1984), 5

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See detailType IV and V collagens in von Recklinghausen's neurofibromas. An immunohistochemical and electrophoretical study.
Peltonen, J.; Foidart, Jean-Michel ULg; Aho, H. J.

in Virchows Archiv. B : Cell pathology (1984), 47(4), 291-301

Type IV and V collagens were localized in neurofibromas from six patients with von Recklinghausen's neurofibromatosis (NF) using the peroxidase anti-peroxidase (PAP) technique. The collagens were also ... [more ▼]

Type IV and V collagens were localized in neurofibromas from six patients with von Recklinghausen's neurofibromatosis (NF) using the peroxidase anti-peroxidase (PAP) technique. The collagens were also isolated from neurofibromas by pepsin digestion and fractionating salt precipitations and demonstrated with sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Staining reactions for both collagens were detected in most of the cells in the disorganized NF tumor tissue. These cells also were S-100 protein-positive and were considered to be of Schwannian cell origin, while the type IV collagen-negative cells showed fibroblastoid, mast cell and histiocytic characteristics. Type IV collagen detection was also used to study the structure of a neurofibroma after 3 weeks in tissue culture. The proportion of fibroblastoid, type IV collagen-negative cells increased significantly in the cultured neurofibromas and "buds" containing solely fibroblastoid cells were seen at the periphery of the tumor fragments. Cultured 6th passage tumor cells produced type V but no type IV collagen as estimated with SDS-PAGE. Further, two malignant Schwannomas from a patient with NF were stained with antibodies to type IV collagen. A positive staining reaction was associated only with the vascular walls in the malignant Schwannomas suggesting that type IV collagen expression is linked with cell differentiation. The present data show that the detection of type IV collagen using the PAP-method is useful in studying the organization of tumors with mixed cell populations such as neurofibromas. Large neurofibromas might also serve as a source for the isolation of human type IV and V collagens. [less ▲]

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See detailConnective tissue elements in rat bone marrow: immunofluorescent visualization of the hematopoietic microenvironment.
Bentley, S. A.; Foidart, Jean-Michel ULg; Kleinman, H. K.

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (1984), 32(1), 114-116

mmunofluorescent staining of frozen sections of rat bone marrow for collagen types I and III revealed the presence of a distinctive, collagen-producing cell type. Morphologically, these cells closely ... [more ▼]

mmunofluorescent staining of frozen sections of rat bone marrow for collagen types I and III revealed the presence of a distinctive, collagen-producing cell type. Morphologically, these cells closely resembled reticular cells. They were large, with branching cytoplasm and were closely related to an extensive intercellular matrix of collagenous material that surrounded the hematopoietic cells of the marrow. Biochemical studies demonstrated synthesis of collagen types I and III, in a ratio of 4:1, by fresh rat bone marrow cells. [less ▲]

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See detailSur le régime alimentaire de la chouette de Tengmalm (Aegolius funereus) en Belgique
Libois, Roland ULg; Gailly, Paul; Destexhe, Pierre

in Aves (1984), 21(1), 57-59

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See detailBacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics
Ghuysen, Jean-Marie ULg; Frère, Jean-Marie ULg; Leyh-Bouille, Mélina et al

in Scandinavian Journal of Infectious Diseases (1984), 42

Wall peptidoglycan expansion in bacteria rests upon a cytoplasmic D-Ala: D-Ala ligase (ADP) which catalyses synthesis of a D-Ala-D-Ala dipeptide (with accompanying hydrolysis of one molecule of ATP) and a ... [more ▼]

Wall peptidoglycan expansion in bacteria rests upon a cytoplasmic D-Ala: D-Ala ligase (ADP) which catalyses synthesis of a D-Ala-D-Ala dipeptide (with accompanying hydrolysis of one molecule of ATP) and a set of DD-peptidases which utilize this D-Ala-D-Ala dipeptide--once it has been translocated at the outer face of the plasma membrane as the C-terminal portion of a disaccharide peptide unit--as carbonyl donor for transpeptidation and carboxypeptidation reactions (without additional energy expenditure). Four DD-peptidases have been selected which differ from each other with respect to the effects that amino compounds exert on the fate and rate of consumption of a D-Ala-D-Ala terminated amide carbonyl donor analogue. They serve as models to understand the different mechanisms by which the DD-peptidases perform catalysis and show widely varying responses to the action of beta-lactams, from extreme sensitivity to very high resistance. [less ▲]

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See detailAtlas des Mammifères sauvages de Wallonie (suite). Le genre Mustela L. en Belgique
Libois, Roland ULg

in Cahiers d'Ethologie (1984), 4(4), 279-313

The distribution and the present status of the polecat, stoat and weasel in Belgium are presented. At this time, these species are widely distribution all over the country and it seems that they aren't ... [more ▼]

The distribution and the present status of the polecat, stoat and weasel in Belgium are presented. At this time, these species are widely distribution all over the country and it seems that they aren't shortly threatened. Some original data on mortality causes are briefly discussed. Undoubtely, it appears that the major ones are trapping and killing by gamekeepers and road casualties, both accounting for more 70 % of the polecat's (n=96) and stoat's (n=45) losses and for 63% (n=101) of the weasel's ones. No information is available about possible death cases due to ingestion of poisoned baits. Poisoning, trapping and hunting are no longeur allowed in the northern part of Belgium (Flanders) but they are permitted in the southern part (Wallony) all over the year without any limitation (except for poisonning). With the legal protection of these animals in prospect, their dietary habits and their main behavioural and demographical characteristics are reviewed. [less ▲]

Detailed reference viewed: 21 (1 ULg)
See detailEvolution of perinatal mortality in 4 maternal health centers in the Walloon region from 1977 to 1982]
Battisti, Oreste ULg; Adam, E.; Heusquin, A. et al

in Revue Médicale de Liège (1984), 39

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See detailSedimentological and paleontological atlas of the Late Famennian and Tournaisian deposits in the Omolon region (NE-USSR)
Shilo, N.A.; Bouckaert, J; Afanesjeva, G.A. et al

in Annales de la Société Géologique de Belgique (1984), 107

Detailed reference viewed: 9 (0 ULg)
See detailUse of an ELISA involving monoclonal antibody for the detection of antibodies against BLV in a herd with high incidence of enzootic bovine leucosis.
Mammerickx, Marc; Portetelle, Daniel ULg; Bruck, Claudine et al

in Zentralblatt für Veterinarmedizin. Reihe B = Journal of Veterinary Medicine. Series B (1984), 31

Detailed reference viewed: 2 (0 ULg)
See detailPhosphate derivatives of thiamine and Na-channel in conducting membranes
Schoffeniels, Ernest; Dandrifosse, Guy ULg; Bettendorff, Lucien ULg

in Journal of Neurochemistry (1984), 43

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See detailTestosterone metabolism and testosterone-dependent characteristics in Japanese quail.
Delville, Y.; Hendrick, J. C.; Sulon, J. et al

in Physiology & Behavior (1984), 33(5), 817-23

In 2 independent experiments, we measured and correlated in maturing male Japanese quail the individual variations in sexual and aggressive behavior, cloacal gland size, testes weight, plasma testosterone ... [more ▼]

In 2 independent experiments, we measured and correlated in maturing male Japanese quail the individual variations in sexual and aggressive behavior, cloacal gland size, testes weight, plasma testosterone concentrations and intracellular testosterone metabolism by hypothalamus and cloacal gland. Cloacal gland area was only weakly related to plasma testosterone levels but was positively correlated with the production of active androgenic metabolites and negatively related to the production of 5 beta-reduced androgens (inactive) in the glandular tissue. Several measures of behavior were correlated with aspects of the testosterone metabolism in the anterior hypothalamus. In both experiments, the behavior of the birds was also strongly correlated with their testes weight and their cloacal gland area but weakly or not at all with their plasma testosterone levels. These studies suggest that testosterone metabolism is involved in the control of hormone action in maturing animals. [less ▲]

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See detailBovine Leukemia Virus (BLV) - A structural model based on chemical crosslinking studies
Uckert, W.; Wunderlich, V.; Ghysdael, Jacques et al

in Virology (1984), 133

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See detailEpithelio-mesenchymal interface and fibronectin in the differentiation of the rat mesonephric and paramesonephric ducts.
Paranko, J.; Pelliniemi, L. J.; Foidart, Jean-Michel ULg

in Differentiation : Research in Biological Diversity (1984), 27(3), 196-204

The distribution of fibronectin and the morphological differentiation of the genital ducts was studied in rat fetuses at ages from 15 to 21 days. Fibronectin was localized with the peroxidase ... [more ▼]

The distribution of fibronectin and the morphological differentiation of the genital ducts was studied in rat fetuses at ages from 15 to 21 days. Fibronectin was localized with the peroxidase-antiperoxidase and avidin-biotin method at the electron- and light-microscope level. In 15-day-old male and female fetuses, fibronectin was localized as a continuous lamella around the mesonephric duct and as a discontinuous lamella around the paramesonephric duct. During the differentiation of the female paramesonephric duct, the fibronectin layer became continuous and remained so after the age of 16 days. The fibronectin layer of the male mesonephric duct remained continuous at all ages. The accumulation of mesenchymal cells on the outer surface of the female mesonephric duct and the concomitant detachment of the fibronectin layer around the duct suggests that mesenchymal regulation plays a role in the regression of the mesonephric duct. In the regressing male paramesonephric duct fibronectin was simultaneously lost in the condensed periductal mesenchyme, the places of epithelio-mesenchymal contact, and the epithelial cytoplasmic protrusions towards the mesenchyme. Ultrastructurally, fibronectin was localized in the basal laminae, on the cell membrane in contact with the extracellular material, and on the surface of the fibrillar and flocculent extracellular material. In addition to auto- and heterophagy, epithelio-mesenchymal interactions seem to play an important role in the regression of the genital ducts, although in different ways in males and females. The present results give additional support to the theory of the possible migration of epithelial cells into the surrounding mesenchyme during the regression of the paramesonephric duct. [less ▲]

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See detailArt et écriture
Duchesne, Jean-Patrick ULg

in Art&fact (1984), 3

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See detailOh, Monsieur Gaston, comme vous parlez bien! : une étude des variations sociolinguistiques dans Gaston Lagaffe
Lafontaine, Dominique ULg

in Enjeux : Revue de Formation Continuée et de Didactique du Français (1984), 5

Detailed reference viewed: 38 (0 ULg)
See detailCompte rendu de J. Kollesch, D. Nickel, Antike Heilkunst. Ausgewählte Texte aus dem medizinischen Schrifttum der Griechen und Römer, Leipzig, 1979
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1984), 53

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See detailSeries episcoporum Ecclesiae Catholicae Occidentalis, t. I
George, Philippe ULg

in Moyen Age (Le) (1984)

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See detailComparaison de deux methodes spectroscopiques d'identification couplees a la chromatographie en phase gazeuse: CPG-SM et CPG-FTIR, dans le cas des isothiocyanates.
Marlier, M.; Wathelet, Jean-Paul ULg; Lognay, Georges ULg et al

in Bulletin des Recherches Agronomiques de Gembloux (1984), 19(3-4),

Les isothiocyanates obtenus après hydrolyse enzymatique des glucosinolates contenus dans les graines de colza sont étudiés par chromatographie en phase gazeuse couplée à la spectrométrie de masse (CPG-SM ... [more ▼]

Les isothiocyanates obtenus après hydrolyse enzymatique des glucosinolates contenus dans les graines de colza sont étudiés par chromatographie en phase gazeuse couplée à la spectrométrie de masse (CPG-SM) et par chromatographie en phase gazeuse couplée à un spectromètre infrarouge à transformée de Fourier (CPG-FTIR). La comparaison de ces deux techniques a permis de mettre en évidence leurs avantages et leurs inconvénients. Elles apportent des informations différentes et donc complémentaires. [less ▲]

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See detailHow should we proceed when a myocardial infarction is suspected
Chapelle, Jean-Paul ULg

in Acta Clinica Belgica (1984), 39(6), 393-5

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See detailIntérêt de la mesure de la fonction du récepteur Fc des monocytes circulants et des macrophages spléniques dans les néphropathies glomérulaires de l'enfant
Davin, J. C.; Foidart, J. B.; Malaise, Michel ULg et al

in Revue Médicale de Liège (1984), 39(8), 332-334

Detailed reference viewed: 6 (3 ULg)
See detailNicoletta CHERUBINI, Pierre nue, poème-légende des photographies de Nguyen Van Thong
Tilkin, Françoise ULg

in Catalogue de l'exposition Pierres nues (Liège, du 26 mai au 30 juin 1984) (1984)

Detailed reference viewed: 21 (4 ULg)
See detailCompte-rendu de l'ouvrage de Rolande Cuvillier: Vers la réduction du temps de travail?
Robert, Jocelyne ULg

in Annals of Public and Cooperative Economics = Annales de l'Economie Publique, Sociale et Coopérative (1984), 4

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See detailEstimation de la surface forestière Wallonne par comptage de points.
Lecomte, H.; Rondeux, Jacques ULg; Laurent, C.

in Bulletin de la Societe Royale Forestiere de Belgique (1984), 91(4), 150-158

The total forest area of Walloonia (south part of Belgium) has been estimated by a dot grid method which consists in counting the number of dots that fall within the boundaries of the forests drawn on ... [more ▼]

The total forest area of Walloonia (south part of Belgium) has been estimated by a dot grid method which consists in counting the number of dots that fall within the boundaries of the forests drawn on maps. All the concerned points were counted and their assignment have been checked on the field (grid of 1000 m x 500 m). According to this method 530.350 hectares should be covered by the forest. [less ▲]

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See detailSynthesis of Communicating Processes from Temporal Logic Specifications
Manna, Zohar; Wolper, Pierre ULg

in ACM Transactions on Programming Languages & Systems (1984), 6(1), 68-93

In this paper, Propositional Temporal Logic (PTL) is applied to the specification and synthesis of the synchronization part of communicating processes. To specify a process, a PTL formula that describes ... [more ▼]

In this paper, Propositional Temporal Logic (PTL) is applied to the specification and synthesis of the synchronization part of communicating processes. To specify a process, a PTL formula that describes its sequence of communications is given. The synthesis is done by constructing a model of the given specifications using a tableau-like satisfiability algorithm for PTL. This model can then be interpreted as a program. [less ▲]

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See detailBlood plasma LH and testosterone concentration in anabolized bulls
Fabry, Jules; Renaville, Robert ULg; Burny, Arsène

in Animal Production (1984), 39

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See detailOn the interpretation of serial laboratory measurements in acute myocardial infarction.
Albert, Adelin ULg; Harris, E K; CHAPELLE, Jean-Paul ULg et al

in Clinical Chemistry (1984), 30(1), 69-76

Serial laboratory determinations are now routinely performed on patients admitted to intensive-care units. Adequate interpretation of such cumulative information for clinical decision-making purposes is a ... [more ▼]

Serial laboratory determinations are now routinely performed on patients admitted to intensive-care units. Adequate interpretation of such cumulative information for clinical decision-making purposes is a challenging problem. We describe a statistical method for predicting--sequentially as the data become available--the patient's outcome, death or survival. Thus, the method goes beyond previously reported techniques that base such prediction on only a single multivariate observation. The method has been applied to daily measurements of serum urea and lactate dehydrogenase, performed during one week on patients hospitalized in the coronary-care unit with acute myocardial infarction. Two baseline variables were also included in the dynamic risk index so derived: the age of the patient and the number of previous myocardial infarctions recorded on admission. We also discuss the problems of selecting the most-predictive laboratory tests and of determining for each test the amount of past data needed to achieve satisfactory prediction. We distinguish between global evaluation of the dynamic risk index obtained (in terms of specificity and sensitivity) and individual interpretation (in terms of posterior/prior probability ratio) of a given risk score for a particular patient. The approach described may contribute to more effective use of results of repeated laboratory tests on critically ill patients. [less ▲]

See detailL'approche scientifique du bien-être des animaux exploités en systèmes d'élevage intensif
Nicks, Baudouin ULg; Bienfait, Jean-Marie ULg

in Annales de Médecine Vétérinaire (1984), 128

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See detailComplement activation in patients at risk of developing the adult respiratory distress syndrome.
Duchateau, J.; Haas, M.; Schreyen, H. et al

in American Review of Respiratory Disease (1984), 130(6), 1058-64

In this prospective study of 50 patients, 36 of whom developed the adult respiratory distress syndrome (ARDS), early and intense complement activation was demonstrated. These patients were at risk of the ... [more ▼]

In this prospective study of 50 patients, 36 of whom developed the adult respiratory distress syndrome (ARDS), early and intense complement activation was demonstrated. These patients were at risk of the ARDS because of multiple injuries, major abdominal surgery, acute pancreatitis, severe burns, or disseminated intravascular coagulation. Abnormal C3 consumption (as measured by the C3d/C3 ratio) and elevated plasma C5a-like activity (as measured by a leukocyte aggregation assay) were associated with, respectively, 84 and 86% of cases of ARDS. Both tests were more sensitive indicators of complement consumption than were assays of total hemolytic complement activity (CH50) or total C3. The C3d/C3 ratio showed a close, inverse correlation with CH50 in 47 healthy subjects, and was increased in 12 control patients after minor surgery. The C5a-like activity was found only in patients at risk of ARDS; it was highly associated with clinical conditions that predispose to the ARDS, but it cannot be considered as a real predictor of ARDS occurrence in these patients. Sequential samples from both sides of the pulmonary circulation showed initial pulmonary clearance followed by the release of C5a-like activity. No simultaneous changes in C3 levels were found, suggesting the possible presence of modulating factors. These observations suggest that other factors (e.g., hypoxia and metabolic cascades) may influence the development of ARDS. [less ▲]

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See detailImmunoreactive trypsin in the adult respiratory distress syndrome
Deby, Ginette ULg; Haas, M.; Pincemail, Joël ULg et al

in Intensive Care Medicine (1984), 10

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See detailGéothermométrie par les pyroxènes et mise en place du massif anorthositique d'Egersund-Ogna (Rogaland, Norvège méridionale)
Maquil, Robert; Duchesne, Jean-Clair ULg

in Annales de la Société Géologique de Belgique (1984), 107

Microprobe analyses are presented of 62 orthopyroxene-clinopyroxene pairs from 17 samples from the Egersund-Ogna anorthositic body. Equilibrium temperatures, calculated by various opx-cpx geothermometers ... [more ▼]

Microprobe analyses are presented of 62 orthopyroxene-clinopyroxene pairs from 17 samples from the Egersund-Ogna anorthositic body. Equilibrium temperatures, calculated by various opx-cpx geothermometers (Wood and Banno, 1973; Wells, 1977), as well as the Al-contents of the pyroxenes show relative variations. The interpretation is consistent with the crystallization of the anorthosite along a PT gradient and the syn-emplacement deformation of the mass itself together with its envelope. [less ▲]

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See detailCloning and structure analysis of the rat apolipoprotein A-I cDNA
Poncin, Jacques; Martial, Joseph ULg; Gielen, Jacques

in European Journal of Biochemistry (1984), 140(3), 493-8

Apolipoprotein A-I, the major protein in mammalian high-density lipoprotein, acts as a cofactor for lecithin-cholesterol acyltransferase during the formation of cholesterol ester and as such, is thought ... [more ▼]

Apolipoprotein A-I, the major protein in mammalian high-density lipoprotein, acts as a cofactor for lecithin-cholesterol acyltransferase during the formation of cholesterol ester and as such, is thought to promote cholesterol efflux from peripheral cells to the liver. In this paper, we report the partial purification of rat liver apolipoprotein A-I mRNA by a polysome immunoadsorption technique, and its cDNA cloning. Isolation of two overlapping cDNA clones enabled us to derive the whole rat apolipoprotein A-I cDNA coding sequence. Comparison of the deduced protein sequence with its human counterpart reveals a striking homology between the prepropeptide precursors. Both mature protein amino-terminal regions are very homologous, suggesting that this particular domain could be involved in lipid/protein binding or lecithin-cholesterol acyltransferase activation. [less ▲]

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See detailInteraction between monobactams and model D-alanyl-D-alanine-cleaving peptidases
Frère, Jean-Marie ULg; Klein, Daniel; Kelly, Judith A et al

in FEMS Microbiology Letters (1984), 21

Several monobactams reacted with the serine dd-peptidases of Streptomyces R61 and Actinomadura R39 in a manner similar to that of bicyclic penicillins and cephalosporins. The dissociation constants of the ... [more ▼]

Several monobactams reacted with the serine dd-peptidases of Streptomyces R61 and Actinomadura R39 in a manner similar to that of bicyclic penicillins and cephalosporins. The dissociation constants of the Michaelis complexes formed between the R61 enzyme and sulfazecin (32 μM) and between the R39 peptidase and SQ 26324 (0.35 μM) had the lowest values ever observed with any β-lactam compound, suggesting an excellent fit of these two monobactams with the active sites of the respective enzymes. Azthreonam had a very poor inactivating potency, confirming its high selective reactivity towards the penicillin binding protein No. 3 of Escherichia coli. The Zn2+dd-peptidase (from Streptomyces albus G) had a high intrinsic resistance to β-lactam compounds whether they possessed a mono- or a bicyclic structure. [less ▲]

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See detailInfluence of opacities, partition functions and hydrogen diffusion on the 5 min solar oscillations
Gabriel, Maurice ULg; Noels-Grötsch, Arlette ULg; Scuflaire, Richard ULg

in Memorie della Società Astronomica Italiana : Journal of the Italian Astronomical Society (1984), 55(1-2), 169-174

Several accuracy tests of the frequencies computation have been performed. They show that for a given model, the frequencies have errors lower than 2 micro-Hz. Several tests have also been made on the ... [more ▼]

Several accuracy tests of the frequencies computation have been performed. They show that for a given model, the frequencies have errors lower than 2 micro-Hz. Several tests have also been made on the Henyey code. They show that the use of the same opacity formula as Bahcall et al. (1983) allows to reproduce their model with a good accuracy. The model has however frequencies systematically 12 micro-Hz larger than found by Ulrich and Rhodes. A model with diffusion of H and He has also been studied. Its frequencies are nearly the same as those of the standard model. [less ▲]

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See detailThe Dissociative ionization of Nitrous Oxide. An Electroionization Study.
Olivier, J. L.; Locht, Robert ULg; Momigny, J.

in International Journal of Mass Spectrometry and Ion Physics (1984), 58

The dissociative electroionization of nitrous oxide into its four dissociation channels has been studied by a method using the kinetic energy and mass analysis. The formation of N2+, NO+, O+ and N+ are ... [more ▼]

The dissociative electroionization of nitrous oxide into its four dissociation channels has been studied by a method using the kinetic energy and mass analysis. The formation of N2+, NO+, O+ and N+ are discussed essentially in terms of predissociation of the ground and excited N2O+ states between 15 and 40 eV. In most cases the predissociating states are also identified. The present results are compared with those in the literature. [less ▲]

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See detailA New Method to Evaluate Wave Impact Forces on Offshores Structures
Marchal, Jean ULg

in Proceedings of the Offshore Technology Conference (1984)

Detailed reference viewed: 8 (0 ULg)
See detailLa « collection médicale » d’Antinoopolis
Marganne, Marie-Hélène ULg

in Zeitschrift für Papyrologie und Epigraphik (1984), 56

Detailed reference viewed: 14 (0 ULg)
See detailUse of the Polymer Polyox XSR 301 in Model Trials of Irland Navigation
Marchal, Jean ULg

in Proceedings of the AIRH Symposium on Scale Effects in Modelling Hydraulic Structures (Technische Akademie, Esslingen) RFA (1984)

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See detailAnalyse des classes de lipides et des acides gras de Leptomysis lingura (Sars) crustacé mysidacé. Influence des condition snutritionnelles.
Hecq, Jean-Henri ULg; Goffart, Anne ULg

in Bulletin de la Société Royale des Sciences de Liège (1984), 1

See pdf file in attachment

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See detailEstradiol contributes to the postnatal demasculinization of female Japanese quail (Coturnix coturnix japonica).
Balthazart, Jacques ULg; Schumacher, M.

in Hormones and Behavior (1984), 18(3), 287-97

Two experiments were performed to characterize the process of postnatal demasculinization in Japanese quail. In the first experiment, it was shown that estradiol (E2) can complete female demasculinization ... [more ▼]

Two experiments were performed to characterize the process of postnatal demasculinization in Japanese quail. In the first experiment, it was shown that estradiol (E2) can complete female demasculinization during the first 4 weeks of life. By contrast, E2 did not demasculinize sexual behavior and cloacal gland in neonatally castrated males. Neonatally gonadectomized females preferentially performed mount attempts when tested in their home cage by comparison to a test arena. In Experiment 2, E2 Silastic implants (40-mm) maintained full copulatory behavior in castrated males but not in females. This large dose of E2 did not demasculinize adult sexually active birds (males or females) even if treatment lasted for 1 month. It is concluded that E2 can demasculinize sexual behavior only in females and only if treatment is performed in very young birds. [less ▲]

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See detailCompte rendu de G. SABBAH (éd.), Médecins et médecine dans l’Antiquité, Saint-Étienne, 1982 (Centre Jean Palerne. Mémoires, III)
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1984), 53

Detailed reference viewed: 4 (0 ULg)
See detailIndicateurs physiologiques de la charge mentale : leur utilité pour le médecin du travail
Mairiaux, Philippe ULg

in Archives des Maladies Professionnelles de Médecine du Travail et de Sécurite Sociale (1984), 45(2), 101-110

Detailed reference viewed: 22 (2 ULg)
See detailImmunohistochemical characterization of the basement membranes of the human oral mucosa.
Salonen, J.; Pelliniemi, L. J.; Foidart, Jean-Michel ULg et al

in Archives of Oral Biology (1984), 29(5), 363-8

Type IV and V collagens, laminin and heparan sulphate proteoglycan were localized in vascular and subepithelial basement membranes. Fibronectin was distributed in a reticular pattern throughout the lamina ... [more ▼]

Type IV and V collagens, laminin and heparan sulphate proteoglycan were localized in vascular and subepithelial basement membranes. Fibronectin was distributed in a reticular pattern throughout the lamina propria under the oral epithelium. The uniform distribution of basement membrane components and type V collagen in different regions suggests a similar molecular composition for the basement membranes under functionally-different oral epithelia. The more intense reaction in the vascular than in the subepithelial basement membranes, with diluted antibodies to type IV collagen and laminin apparently reflects chemical differences in these basement membranes. Occasional discontinuities in the subepithelial basement membranes were seen in inflamed gingival sulci and in tonsillar crypts. The destruction responsible affected all basement membrane components, except fibronectin, which maintained a reticular distribution even in the deep tonsillar tissue. The immunohistochemical method is useful in demonstrating different degrees of destruction in basement membranes associated with inflammation. [less ▲]

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See detailQuand des parents posent des questions à leurs jeunes enfants
Lafontaine, Dominique ULg

in Enfance (1984), 1

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See detailIsolation and characterization of the human prolactin gene
Truong, Anh T; Duez, Colette ULg; Belayew, Alexandra et al

in EMBO Journal (1984), 3(2), 429-37

Prolactin (PRL) and growth hormone (GH) genes derive from a common ancestor and still share some sequence homologies. Their expression in the pituitary gland is regulated in opposite directions by most of ... [more ▼]

Prolactin (PRL) and growth hormone (GH) genes derive from a common ancestor and still share some sequence homologies. Their expression in the pituitary gland is regulated in opposite directions by most of the many hormones acting on them. This provides an interesting system to study sequences involved in gene expression. Using a human PRL cDNA clone as a probe, we screened a human genomic DNA library in lambda phage and isolated a single recombinant comprising the whole hPRL gene. It was characterized by restriction endonuclease mapping and cDNA hybridization, by DNA heteroduplex analysis and by nucleotide sequencing. The hPRL gene is present as a single copy per haploid genome, is approximately 10 kb long and contains four introns, three of which interrupt the coding sequence at the same locations as in the known GH and PRL genes. The origin of transcription was determined by S1 mapping on prolactinoma mRNAs. The search for direct and inverted repeats, as well as dyad symmetries was carried out in the 900-bp sequenced in the 5'-flanking region. Sequence homologies between hPRL, hGH and rPRL were derived from computer drawn matrices for these upstream regions. [less ▲]

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See detailLa sécurité sociale belge en question
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Revue Française de Finances Publiques [=RFFP] (1984), (8), 123-136

Detailed reference viewed: 17 (1 ULg)
See detailEtude dendrométrique des ormes (Ulmus glabra Huds. et Ulmus campestris L.)
Thill, A.; Palm, Rodolphe ULg

in Notes Techniques du Centre d'Ecologie Forestière et Rurale (1984), 45

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See detailActive-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G.
Charlier, Paulette ULg; Dideberg, Otto; Jamoulle, Jean-Claude et al

in Biochemical Journal (1984), 219(3), 763-772

Several types of active-site-directed inactivators (inhibitors) of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase were tested. (i) Among the heavy-atom-containing compounds examined ... [more ▼]

Several types of active-site-directed inactivators (inhibitors) of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase were tested. (i) Among the heavy-atom-containing compounds examined, K2Pt(C2O4)2 inactivates the enzyme with a second-order rate constant of about 6 X 10(-2)M-1 X S-1 and has only one binding site located close to the Zn2+ cofactor within the enzyme active site. (ii) Several compounds possessing both a C-terminal carboxylate function and, at the other end of the molecule, a thiol, hydroxamate or carboxylate function were also examined. 3-Mercaptopropionate (racemic) and 3-mercaptoisobutyrate (L-isomer) inhibit the enzyme competitively with a Ki value of 5 X 10 X 10(-9)M. (iii) Classical beta-lactam compounds have a very weak inhibitory potency. Depending on the structure of the compounds, enzyme inhibition may be competitive (and binding occurs to the active site) or non-competitive (and binding causes disruption of the protein crystal lattice). (iv) 6-beta-Iodopenicillanate inactivates the enzyme in a complex way. At high beta-lactam concentrations, the pseudo-first-order rate constant of enzyme inactivation has a limit value of 7 X 10(-4)S-1 X 6-beta-Iodopenicillanate binds to the active site just in front of the Zn2+ cofactor and superimposes histidine-190, suggesting that permanent enzyme inactivation is by reaction with this latter residue. [less ▲]

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See detailEffect of somatic growth on pulmonary function values in healthy Friesian cattle
Lekeux, Pierre ULg; Hajer, R.; Breukink, H. J.

in American Journal of Veterinary Research (1984), 45(10), 2003-2007

Growth-related changes in pulmonary function values (PFV) of cattle were investigated by a cross-sectional study of 40 healthy Dutch Friesian cattle, 3 days to 13 years of age and weighing 37 to 660 kg ... [more ▼]

Growth-related changes in pulmonary function values (PFV) of cattle were investigated by a cross-sectional study of 40 healthy Dutch Friesian cattle, 3 days to 13 years of age and weighing 37 to 660 kg. Technical and methodologic procedures and body conformation and condition were standardized. A regression analysis was done with 4 independent variables (body weight, thoracic perimeter, body surface area, and age) and with PFV measured in this study. Ventilation values, dynamic lung compliance, and viscous work of breathing changed linearly with somatic growth. Respiratory frequency, total pulmonary resistance, and arterial oxygen tension showed an exponential relationship with all the independent variables. On the other hand, intrapleural pressure values were weakly correlated with body size indexes. The most important growth-related changes in PFV occurred at approximately 1 year of age. A significant (P less than or equal to 0.05) difference between immature and mature cattle was shown for the blood-gas values and the specific values of the breathing mechanics. The dynamic lung compliance/lung weight was lower and the total pulmonary resistance X minute volume was higher in cattle than in other domestic mammals. The regression equation, giving the best fit of the data, was selected for each PFV. [less ▲]

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See detailCalculation of autocorrelation functions for electronic spectra
Dehareng, Dominique ULg

in Chemical Physics (1984), 84

The autocorrelation function C(t) associated with the vibrational motion in the A 2Pi u state of N2+ is calculated by three different methods. The classical method is based on classical trajectory ... [more ▼]

The autocorrelation function C(t) associated with the vibrational motion in the A 2Pi u state of N2+ is calculated by three different methods. The classical method is based on classical trajectory calculations and provides good results except for secondary maxima appearing in the experimental autocorrelation function and resulting from interference effects. In the semiclassical method, the wavefunction is expanded in a basis of frozen gaussian functions. The secondary maxima are reproduced and the result is quite satisfactory. The superposition procedure consists in an expansion of the wavefunction in the eigenfunctions of the A state of N2+ and leads to a very simple formula for the autocorrelation function C(t). The secondary maxima are accounted for and the calculated function agrees very well with experimental results. [less ▲]

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