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See detailComparant mais pas fondateur
Caprasse, Olivier ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailUntersuchung von Spaltungs- und Koaleszenzvorgängen in einer Messzelle mit pulsierten Füllkörpern
Klinger, S; Henschke, M; Pfennig, Andreas ULg

in Chemie Ingenieur Technik (2002), 74(3), 256-261

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See detailApplication de Pichia anomala souche K, Beta 1,3-glucanes et chlorure de Calcium pour le contrôle des maladies de conservation des pommes en conditions proches de la pratique
Jijakli, Haissam ULg; Dickburt, C.; De Clerck, D. et al

in Colloque transnational sur les luttes biologiques, intégrée et raisonnée (2002)

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See detailOver Kathrin Kötz, Die Prosa Paul van Ostaijens
Spinoy, Erik ULg

in Nachbarsprache Niederländisch (2002), 17(1-2), 122-125

This is a review of a study by Katrhin Kötz on Paul van Ostaijen's literary ('grotesque') prose and its German influences.

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See detailFirst-principles computation of material properties: the ABINIT software project
Gonze, X.; Beuken, J. M.; Caracas, R. et al

in Computational Materials Science (2002), 25(3), 478-492

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a ... [more ▼]

The density functional theory (DFT) computation of electronic structure, total energy and other properties of materials, is a field in constant progress. In order to stay at the forefront of knowledge, a DFT software project can benefit enormously from widespread collaboration, if handled properly. Also, modern software engineering concepts can considerably ease its development. The ABINIT project relies upon these ideas: freedom of sources, reliability, portability, and self-documentation are emphasised, in the development of a sophisticated plane-wave pseudopotential code. We describe ABINITv3.0, distributed under the GNU General Public License. The list of ABINITv3.0 capabilities is presented, as well as the different software techniques that have been used until now: PERL scripts and CPP directives treat a unique set of FORTRAN90 source files to generate sequential (or parallel) object code for many different platforms; more than 200 automated tests secure existing capabilities; strict coding rules are followed; the documentation is extensive, including online help files, tutorials, and HTML-formatted sources. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailA pulsating auroral X-ray hot spot on Jupiter
Gladstone, G. R.; Waite, J. H.; Grodent, Denis ULg et al

in Nature (2002), 415(6875), 1000-1003

Jupiter's X-ray aurora has been thought to be excited by energetic sulphur and oxygen ions precipitating from the inner magnetosphere into the planet's polar regions(1-3). Here we report high-spatial ... [more ▼]

Jupiter's X-ray aurora has been thought to be excited by energetic sulphur and oxygen ions precipitating from the inner magnetosphere into the planet's polar regions(1-3). Here we report high-spatial-resolution observations that demonstrate that most of Jupiter's northern auroral X-rays come from a 'hot spot' located significantly poleward of the latitudes connected to the inner magnetosphere. The hot spot seems to be fixed in magnetic latitude and longitude and occurs in a region where anomalous infrared(4-7) and ultraviolet(8) emissions have also been observed. We infer from the data that the particles that excite the aurora originate in the outer magnetosphere. The hot spot X-rays pulsate with an approximately 45-min period, a period similar to that reported for high-latitude radio and energetic electron bursts observed by near-Jupiter spacecraft(9,10). These results invalidate the idea that jovian auroral X-ray emissions are mainly excited by steady precipitation of energetic heavy ions from the inner magnetosphere. Instead, the X-rays seem to result from currently unexplained processes in the outer magnetosphere that produce highly localized and highly variable emissions over an extremely wide range of wavelengths. [less ▲]

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See detailUse of Anesthesia Simulator
Pendeville, Philippe; Mayne, Alain; LARBUISSON, Robert ULg et al

in Benelux quaterly journal on automatic control (2002), 43(2), 17-19

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See detailStudy of the role of ionogenic amino-acid residues in catalytic activity of thiamine triphosphatase from bovine kidney by means of chemical modification
Makarchikov, Alexander F; Luchko, A. A.; Bettendorff, Lucien ULg et al

in News of Biomedical Sciences (2002), 3

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See detailUnusual traits of the pyoverdin-mediated iron acquisition system in Pseudomonas putida strain BTP1.
Ongena, MARC ULg; Jacques, Philippe ULg; Delfosse, Philippe et al

in Biometals (2002), 15(1), 1-13

Fluorescent Pseudomonas species are characterized by the production of pyoverdin-type siderophores for Fe3+ acquisition in iron-limited environments. Since it produces a structurally specific pyoverdin ... [more ▼]

Fluorescent Pseudomonas species are characterized by the production of pyoverdin-type siderophores for Fe3+ acquisition in iron-limited environments. Since it produces a structurally specific pyoverdin, Pseudomonas putida strain BTP1 could represent a valuable tool in an attempt to correlate the structural features of these compounds with some specificity in their two main properties i.e. affinity for iron and recognition rate by other Pseudomonas strains. An uncommonly high affinity for iron of the pyoverdin synthetized by P. putida BTP1 was observed by comparing both the apparent stability constant and the decomplexation kinetic of its ferric complex with those of ferripyoverdins from other strains. On another hand, results from growth stimulation experiments and labeled ferripyoverdin uptake assays highlighted the very low recognition rate of BTP1 isopyoverdins by membrane receptors of foreign strains. By contrast, P. putida BTP1 was able to utilize a broad spectrum of structurally unrelated exogenous pyoverdins by means of multiple receptors that are likely constitutively expressed in its outer membrane. The unusual traits of its pyoverdin-mediated iron acquisition system should contribute to enlarge the ecological competence of Pseudomonas putida BTP1 in terms of colonization and persistence in the rhizosphere. [less ▲]

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See detailResults of obesity treatment.
Scheen, André ULg

in Annales d'Endocrinologie (2002), 63(2 Pt 1), 163-70

Obesity is a chronic disease so that results of obesity treatment should only be evaluated on a long-term basis. The present paper aims at analyzing the long-term (1 year or more) results of three anti ... [more ▼]

Obesity is a chronic disease so that results of obesity treatment should only be evaluated on a long-term basis. The present paper aims at analyzing the long-term (1 year or more) results of three anti-obesity approaches, i.e. lifestyle modifications, pharmacological treatments and surgical procedures. Dietary interventions include diets with moderate calorie restriction and very-low energy diets (VLED). Even if an initial greater weight loss is observed with VLED, no study has conclusively shown that the long-term approaches including VLED are better than non-VLED programmes. Physical activity is not the most efficient method of initial weight loss, but it appears to be more crucial for maintaining weight loss once it has occurred. In general, long-term results of lifestyle modifications are disappointing because of poor compliance. Several 1-2 year large-scale randomized placebo-controlled clinical trials with orlistat, an intestinal lipase inhibitor, and sibutramine, a central appetite regulator, have demonstrated that both drugs significantly, although modestly on average, increase weight reduction, almost double the number of responders (weight loss >=5 or 10% of initial body weight) and improve weight maintenance up to 2 years. Surgical procedures provide a much greater weight reduction than medical interventions in patients with morbid obesity, particularly after a follow-up of several years. Weight loss is greater with gastric bypass, inducing some malbsorption, than with gastroplasty, a pure gastric restriction technique. Associated risk factors such as markers of insulin resistance syndrome and type 2 diabetes are remarkably reduced, but no prospective study of morbidity or mortality is available yet. In all cases, the management of obesity requires a multidisciplinary approach to improve the success rate. [less ▲]

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See detailPharma clinics. Comment je traite ... un herpes labial récurrent.
Petit, L.; Braham, C.; Nikkels, Arjen ULg et al

in Revue Médicale de Liège (2002), 57(2), 67-71

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent ... [more ▼]

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent labial herpes are targeted by specific antiviral agents. Spectacular benefits obtained in the immunocompromised patients are less convincing in otherwise healthy subjects. Other prospective ways of therapy are under consideration, including lipopeptides and physical means aiming at modifying the cutaneous pH. [less ▲]

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See detailEntre Italie et Pays-Bas méridionaux. Le « Libro de memoria » de la famille Cassina. 1576-1650.
Moreno, Paola ULg

in Studi e Problemi di Critica Testuale (2002)

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See detailCombined implicit-explicit algorithms for non-linear structural dynamics
Noels, Ludovic ULg; Stainier, Laurent ULg; Ponthot, Jean-Philippe ULg et al

in Revue Européenne des Éléments Finis (2002), 11(5), 565-591

To solve fast dynamic problems, an explicit method is the most adapted. But for slower dynamics, an implicit method is more stable. The industrial problems are governed by high frequency (impact ... [more ▼]

To solve fast dynamic problems, an explicit method is the most adapted. But for slower dynamics, an implicit method is more stable. The industrial problems are governed by high frequency (impact, ...) during short time intervals and slower dynamics (spring-back, ...) during other time intervals. The optimal solution is then to have both implicit algorithm and explicit methods readily available in the same code and to be able to switch automatically from one to another. Criteria that decide when to shift from a method to another have been developed here. Implicit balanced restarting conditions that annihilate numerical oscillations resulting for an explicit calculation are also proposed. [less ▲]

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See detailStimulation of collagen biosynthesis by topically applied vitamin C.
Nusgens, Betty ULg; Humbert, P.; Rougier, A. et al

in European Journal of Dermatology (2002), 12(4), -

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See detailInventories and Maps: Cognitive Ways of Framing the Nature Policies in Europe
Mougenot, Catherine ULg; Remy, Elisabeth

in Journal of Environmental Policy & Planning (2002), 4(4), 313-322

Since the Earth Summit in Rio, declining biodiversity has become a subject of general concern for many countries. To counter these negative trends, government nature policies in Europe at least are now ... [more ▼]

Since the Earth Summit in Rio, declining biodiversity has become a subject of general concern for many countries. To counter these negative trends, government nature policies in Europe at least are now thought out primarily in terms of networks. They concern new areas outside nature reserves, new players and new management strategies. Consequently, these policies should themselves become the subject of new public debate. Our study concerns the analysis of the forms used to collect the data required to set up the European Union's Natura 2000 network and maps drawn as part of the Council of Europe's Pan-European Ecological Network strategy. The aim of this article, which takes the perspective developed by the sociology of science, will be to show how the forms and maps used in these new nature policies produce knowledge that precedes policy discussions to search for the best possible socio-political compromises. In other words, the knowledge that is collected in and by means of these documents, forms and maps offers a cognitive way of framing the subsequent public debates. [less ▲]

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See detailSynthesis of 2-amino-1,4-dihydro-4-quinolinones and diaminomethylene Meldrum’s acids derivatives as potential potassium channel openers
Erb, B.; Rigo, B.; Pirotte, Bernard ULg et al

in Journal of Heterocyclic Chemistry (2002), 39

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See detailHormonal measurements in late pregnancy and parturition in dairy cows - possible tools to monitor foetal well being
Kornmatitsuk, B.; Veronesi, M. C.; Madej, A. et al

in Animal Reproduction Science (2002), 72(3-4), 153-164

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The ... [more ▼]

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The following parameters were registered: degrees of calving difficulty, date and time of parturition, calf's birth weight and calf's sex. Body temperature was measured and blood samples were taken every 3 h 3 days before the first PGF(2alpha) injection until 3 days after parturition. The plasma concentrations of the PGF2a metabolite, progesterone, cortisol, oestrone sulphate and pregnancy associated glycoproteins (PAGs) were analysed. Heifers A, B and C delivered 48, 51 and 57 h after the first PGF(2alpha) injection, respectively. Heifer A delivered without any signs of calving difficulty, whereas, the parturition was considered to be slight and moderate difficulty occurred in the delivery of heifers B and C, respectively. The calf of heifer C, without any abnormal gross-evidences, was stillborn. All animals had retained foetal membranes. A slight increase of the PGF(2alpha) metabolite at the time of parturition was found only in heifer C, whereas the levels dramatically increased in all animals 15-24 h after parturition. At the same time, progesterone levels decreased within 3 h after the first PGF(2alpha) injection (P < 0.05) and reached 0.8, 2.7 and 12.4 nmol/l at the time of parturition in heifers A, B and C, respectively. High release of cortisol at the time of parturition was seen in heifer C. Rising levels of oestrone sulphate around the time of parturition were recorded in all heifers, whereas, increasing levels of PAGs were recorded only in heifer A. In conclusion, the patterns of the PGF(2alpha) metabolite, cortisol, progesterone and PAGs were changed in the cases of calving difficulty and stillbirth after PGF(2alpha)-induction of parturition. However, the relationship between oestrone sulphate and PAGs and the status of foetal well being prior to parturition require further elucidation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailGeneralized Fourier equations and thermoconvective instabilities
Dauby, Pierre ULg; Nelis, M.; Lebon, Georgy ULg

in Revista Mexicana De Fisica (2002), 48(Suppl. 1), 57-62

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See detailLes sans-papiers en Belgique
Martiniello, Marco ULg; Rea, Andrea

in Hommes & Migrations (2002), 1238

Qui sont ces “exclus de l’intérieur”, ces “sans-droits”, générés par une Belgique dont la politique d’immigration s’adapte mal aux nouveaux migrants ? Une étude, menée auprès de cent trente sans-papiers ... [more ▼]

Qui sont ces “exclus de l’intérieur”, ces “sans-droits”, générés par une Belgique dont la politique d’immigration s’adapte mal aux nouveaux migrants ? Une étude, menée auprès de cent trente sans-papiers et clandestins, rend compte de la précarité de leurs conditions de vie. L’analyse des données recueillies permet de dresser un portrait sociologique précis de cette population, et d’examiner à la loupe la misère des conditions de départ, la clandestinité, le travail au noir. Les auteurs de l’étude expliquent, notamment, pourquoi certains sans-papiers n’ont pas cherché à régulariser leur situation, malgré la vaste campagne lancée par les pouvoirs publics en 2000. [less ▲]

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See detailEthno-Ecological approach of Tibet south-central rural environment knowledge as a support to Kashin-Beck disease's etiology
Malaisse, François ULg; Begaux, Françoise; Chasseur, Camille et al

in Bulletin des Séances de l'Académie Royale des Sciences d'Outre-Mer (2002), 48

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See detailModellierung von Faserbett-Koaleszenzabscheidern
Speth, H; Pfennig, Andreas ULg; Chatterjee, M et al

in Chemie Ingenieur Technik (2002), 74(3), 266-270

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See detailGénération d'un maillage pour éléments finis à partir de fichiers stéréolithographie (STL) : une interface indépendante des formats de CAO
Béchet, Eric ULg; Cuillière, Jean-Christophe; Trochu, François

in Revue internationale de CFAO et d'informatique graphique (2002), 17/1-2

The aim of the method proposed here is to show the possibility of generating adaptive surface meshes suitable for the finite element method, directly from an approximated boundary representation of an ... [more ▼]

The aim of the method proposed here is to show the possibility of generating adaptive surface meshes suitable for the finite element method, directly from an approximated boundary representation of an object created with CAD software. First, we describe the boundary representation, then we will show how to obtain a conforming sizeadapted mesh. The size adaptation is made considering geometrical approximation and with respect to an isotropic size map provided by an error estimator. The principle used to generate the mesh is based on the Delaunay method. Finally, we will show that not using the parametric representation of the geometrical model allows us to override some of the limitations of conventional meshing software that is based on an exact representation of the geometry. [less ▲]

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See detailRunoff control of soil degassing at an active volcano. The case of Piton de la Fournaise, Reunion Island
Toutain, J. P.; Baubron, J. C.; François, Louis ULg

in Earth And Planetary Science Letters (2002), 197(1-2), 83-94

Airborne atmospheric and in-situ soil gas analyses demonstrate that distal gas leaks are non-existent at Piton de la Fournaise (PF) despite frequent eruptions. Airborne traverses made at a constant ... [more ▼]

Airborne atmospheric and in-situ soil gas analyses demonstrate that distal gas leaks are non-existent at Piton de la Fournaise (PF) despite frequent eruptions. Airborne traverses made at a constant altitude indicated that no detectable large-scale CO2 degassing occurs from the volcano. In-situ soil gas traverses (CO2, He-4, Rn-222) across the active riftzones, the summit crater and the caldera rims, show both a lack of positive anomalies and evidence of strong depleted concentrations for He and CO2 with respect to air. Depletions in soil He is explained by intense rain water infiltration. A more unexpected result lies in the very low CO2 concentrations (down to 92 ppm) in bare soils in the summit region. Such a depletion was not previously reported and is attributed to considerable basalt weathering operating as the result of huge runoff. A model has enabled both the runoff and the CO2 consumption occurring within the basaltic layers to be calculated. Data obtained are consistent with values expected from large-scale erosion models and with the local calculated diffusive flux of CO2 in soils. The huge runoff, together with the basaltic lithology of the volcano, are found to be the main factor controlling the soil gas signatures at PF. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailA Set Of Primers For Amplification Of Mitochondrial Dna In Picea Abies And Other Conifer Species
Jeandroz, S.; Bastien, D.; Chandelier, A. et al

in Molecular Ecology Notes (2002), 2(4),

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See detailConditions d'application et transformations de variables en régression linéaire
Palm, Rodolphe ULg; Iemma, A. F.

in Notes de Statistique et d'Informatique (2002), (1), 1-34

This note first reviews methods used for checking the assumptions in linear regression (lack of fit, normality, homoscedasticity and independance of the residuals) and then describes variables ... [more ▼]

This note first reviews methods used for checking the assumptions in linear regression (lack of fit, normality, homoscedasticity and independance of the residuals) and then describes variables transformations as remedial action when the assumptions are not fulfilled. [less ▲]

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See detailCambios en la participación política de los inmigrantes en la región de Bruselas capital. Elecciones de octubre de 2000
Martiniello, Marco ULg; Jacobs, Dirk; Rea, Andrea

in Revista Migraciones (2002), 11

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See detailLa réforme de l'adoption pas à pas. Note sous C.A., 28 novembre 2001
Leleu, Yves-Henri ULg

in Journal des Tribunaux (2002)

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See detailAg/SiO2 and Cu/SiO2 cogelled xerogel catalysts for benzene combustion and 2-butanol dehydrogenation
Lambert, Stéphanie ULg; Tcherkassova, Natalia; Cellier, Caroline et al

in Studies in Surface Science and Catalysis (2002), 143

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See detailPrognosis of hematologic malignancies does not predict intensive care unit mortality.
MASSION, Paul ULg; Dive, Alain M; Doyen, Chantal et al

in Critical Care Medicine (2002), 30(10), 2260-70

OBJECTIVE: To evaluate the correlation between specific prognosis of hematologic malignancies on the one hand and intensive care unit and hospital mortality in critically ill patients with hematologic ... [more ▼]

OBJECTIVE: To evaluate the correlation between specific prognosis of hematologic malignancies on the one hand and intensive care unit and hospital mortality in critically ill patients with hematologic malignancies on the other hand. DESIGN: Observational study during a 10-yr period. SETTING: A 22-bed medical-surgical intensive care unit. PATIENTS: A total of 84 consecutive patients with nonterminal hematologic malignancies with medical complications requiring intensive care. INTERVENTIONS: None. MEASUREMENTS: Demographic factors, acute physiology and organ dysfunction scores, microbiology, therapeutic support, and hematologic factors data on admission and during the intensive care unit stay were collected, together with mortality follow-up. Based on specific-disease prognostic factors and related published survival curves, the prognosis of hematologic malignancies was assessed and defined as good, intermediate, or poor according to a 3-yr survival probability of >50%, 20-50%, or <20%, respectively. MAIN RESULTS: Prognosis of hematologic malignancies does not predict intensive care unit or hospital mortality and almost reaches significance for 6-mo mortality (53%, 71%, and 84% rate for patients with good, intermediate, and poor prognosis, respectively, p =.058), but it determines long-term survival (p =.008). Intensive care unit, hospital, and 6-mo overall mortality rates were 38%, 61%, and 75%, respectively. Using multivariate analysis, intensive care unit mortality was best predicted on admission by respiratory failure and fungal infection, whereas hospital mortality was predicted by the number of organ failures, the bone marrow transplant status, and the presence of fungal infection. The Acute Physiology and Chronic Health Evaluation II and the Simplified Acute Physiology Score II had no prognostic value, whereas the difference of the Multiple Organ Dysfunction Score between at the time of admission and at day 5 allowed quick prediction of hospital mortality. Diseases with the poorest 6-mo prognosis were acute myeloid leukemia and non-Hodgkin lymphoma. CONCLUSION The severity of the underlying hematologic malignancies does not influence intensive care unit or hospital mortality. Short-term prognosis is exclusively predicted by acute organ dysfunctions and by a pathogen's aggressiveness. Therefore, reluctance to admit patients with nonterminal hematologic malignancies to the intensive care unit based only on the prognosis of their underlying hematologic malignancy does not seem justified. [less ▲]

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See detailAdhesion of synchronized human hematopoietic progenitor cells to fibronectin and vascular cell adhesion molecule-1 fluctuates reversibly during cell cycle transit in ex vivo culture.
Huygen, Sandra; Giet, Olivier ULg; Artisien, Vincent et al

in Blood (2002), 100(8), 2744-52

Ex vivo expansion of hematopoietic stem/progenitor cells may result in defective engraftment. Human cord blood CD34(+) progenitor cells were synchronized and assayed for adhesion and migration onto ... [more ▼]

Ex vivo expansion of hematopoietic stem/progenitor cells may result in defective engraftment. Human cord blood CD34(+) progenitor cells were synchronized and assayed for adhesion and migration onto fibronectin (Fn) and vascular cell adhesion molecule-1 (VCAM-1) at different stages of a first cell cycle executed ex vivo. During S phase transit, adhesion to Fn was transiently increased while binding to VCAM-1 was reversibly decreased, after which adhesion to both ligands returned to baseline levels with cell cycle completion. Transmigration across Fn and VCAM-1 decreased irreversibly during S phase progression. The function of alpha4 and alpha5 integrins was assessed with specific neutralizing antibodies. In uncultured CD34(+) cells and long-term culture-initiating cells (LTC-ICs), both adhesion and migration on Fn were inhibited by anti-alpha4 but not by anti-alpha5 antibodies. In mitotically activated CD34(+) cells and LTC-ICs, adhesion and migration on Fn were mainly dependent on alpha5 integrin and to a lesser extent on alpha4 integrin. Changes in integrin function were not dependent on parallel modulation of integrin expression. In conclusion, Fn and VCAM-1 binding of progenitor cells fluctuates reversibly during cell cycle transit ex vivo. In addition, our data show that mitogenic activation induces a shift from a dominant alpha4 to a preferential alpha5 integrin-dependent interaction with Fn. [less ▲]

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See detailSmearing scheme for finite-temperature electronic-structure calculations
Verstraete, Matthieu ULg; Gonze, X.

in Physical Review. B : Condensed Matter (2002), 65

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See detailResonance-assisted tunneling
Brodier, O.; Schlagheck, Peter ULg; Ullmo, D.

in Annals of Physics (2002), 300(1), 88-136

We present evidence that tunneling processes in near-integrable systems are enhanced due to the manifestation of nonlinear resonances and their respective island chains in phase space. A semiclassical ... [more ▼]

We present evidence that tunneling processes in near-integrable systems are enhanced due to the manifestation of nonlinear resonances and their respective island chains in phase space. A semiclassical description of this "resonance-assisted" mechanism is given, which is based on a local perturbative description of the dynamics in the vicinity of the resonances. As an underlying picture, we obtain that the quantum state is coupled, via a succession of classically forbidden transitions across nonlinear resonances, to high excitations within the well, from where tunneling occurs with a rather large rate. The connection between this description and the complex classical structure of the underlying integrable dynamics is furthermore studied, giving ground to the general coherence of the description as well as guidelines for the identification of the dominant tunneling paths. The validity of this mechanism is demonstrated within the kicked Harper model, where good agreement between quantum and semiclassical (resonance-assisted) tunneling rates is found. (C) 2002 Elsevier Science (USA). [less ▲]

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See detailModulation par le cycle cellulaire de l'implantation des cellules souches hématopoïétiques
Gothot, André ULg; Giet, Olivier ULg; Huygen, S. et al

in Hématologie (2002), 8

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See detailPhase And Amplitude Of Ecosystem Carbon Release And Uptake Potentials As Derived From Fluxnet Measurements
Falge, Eva; Tenhunen, John; Baldocchi, Dennis et al

in Agricultural and Forest Meteorology (2002), 113(1-4),

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See detail- La bande dessinée muette et le texte
Paques, Frédéric ULg

in Art&Fact (2002), 21

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See detailEuro- en zijn concurrenten
Meesters, Gert ULg

in Leuvense Bijdragen (2002), 91(1-2), 79-96

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the ... [more ▼]

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the European currency. The article especially deals with the relationship between word formation with euro- and three other means of expressing more or less the same meaning: word formation with EG- (abbreviation of Europese Gemeenschap, i.e. European Union) as a first component, word formation with Europa- (Europe) as a first component and word groups with the adjective Europees (European). This relationship is explored in two comparative studies. First the token frequency in a corpus is investigated. It turns out that euro- is more frequent than Europa-, but less frequent than EG- and Europees. In a second comparison the semantic-functional domains of the four alternatives are considered in detail. Euro- apparently can be used as an alternative for Europees and EG- when the referents are related to the European Union, and as an alternative for Europees in ‘bilateral’ adjectives such als Euro-Russisch. It also has a few domains of its own: commercial proper names and words expressing an attitude towards the European Union. An additional analysis of individual words and word groups with different alternatives from this paradigm as a first component but the same second component reveals that even in individual cases of competition with other alternatives, the variant with euro- is sometimes the most frequent or the institutionalized form. It is concluded that within the linguistic potential of naming referents that relate to Europe, euro- has its own specific value as a productive means of word formation. [less ▲]

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See detailErythropoiesis after nonmyeloablative stem-cell transplantation is not impaired by inadequate erythropoietin production as observed after conventional allogeneic transplantation.
Baron, Frédéric ULg; Fillet, Georges ULg; Beguin, Yves ULg

in Transplantation (2002), 74(12), 1692-6

BACKGROUND: It is now well established that after conventional allogeneic hematopoietic stem-cell transplantation (HSCT), erythropoietic recovery is impaired because erythropoietin (Epo) production ... [more ▼]

BACKGROUND: It is now well established that after conventional allogeneic hematopoietic stem-cell transplantation (HSCT), erythropoietic recovery is impaired because erythropoietin (Epo) production remains inadequate for prolonged periods of time. However, erythropoietic reconstitution after nonmyeloablative SCT (NMSCT) has never been characterized. METHODS: Twelve patients received a nonmyeloablative conditioning regimen consisting of 2 Gy total body irradiation (TBI) alone (n=6), 2 Gy TBI and fludarabine (n=3), or cyclophosphamide and fludarabine (n=3), followed by transplantation of allogeneic peripheral blood stem cells. Graft-versus-host-disease (GvHD) prophylaxis was carried out with mycophenolate mofetil (from day -1 to day 28) plus cyclosporine (from day -1 to day 120 or longer in case of chronic GvHD). Erythropoiesis was quantitated by soluble transferrin receptor (sTfR) levels, and the adequacy of Epo production was evaluated by the observed-to-predicted Epo ratio (O/P Epo). RESULTS: Mean sTfR levels decreased following the conditioning regimen but remained well within the normal range throughout the posttransplant period. The O/P Epo ratio presented an initial surge quite similar to that observed after conventional conditioning. Thereafter, the O/P Epo ratio normalized rapidly, and Epo levels remained adequate during the whole observation period. CONCLUSION: Contrarily to what is observed after myeloablative transplant, Epo levels remained adequate after NMSCT, resulting in normal erythropoiesis. These results suggest that the administration of erythropoietin therapy (rHuEpo) could be less effective after NMSCT than after conventional allogeneic transplant. [less ▲]

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See detailComparison of plasma cardiac troponins T and I in chronically hemodialyzed patients in relation to cardiac status and age
Chapelle, Jean-Paul ULg; Dubois, Bernard ULg; Bovy, Christophe ULg et al

in Clinical Chemistry & Laboratory Medicine (2002), 40(3), 240-245

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See detailQuantitative dilatometric analysis of intercritical annealing in a low-silicon TRIP steel
Zhao, Lie; Kop, T. A.; Rolin, Valéry et al

in Journal of Materials Science (2002), 37

In this work, an evaluation method to calculate the austenite fraction during continuous heating and isothermal annealing from dilatometric data is proposed. By means of a single reference measurement to ... [more ▼]

In this work, an evaluation method to calculate the austenite fraction during continuous heating and isothermal annealing from dilatometric data is proposed. By means of a single reference measurement to determine a scaling factor correcting for experimental errors, a framework is created to determine the austenite fraction as a function of time and temperature. In the evaluation of the dilatometric data the effect of the changing carbon concentration in austenite phase is taken into account. The method is applied to dilatometric data for a 0.16C-1.5Mn-0.4Si (wt%) low-silicon transformation induced plasticity (TRIP) multiphase steel. Three typical dilatometric data are obtained by heating the material to 750°C, 800°C or 900°C, which leads to three different microstructures consisting of (1) ferrite, cementite and austenite, (2) ferrite and austenite and (3) full austenite, respectively. The calculated results using the proposed new method are compared with the results from thermodynamic analysis and those from quantitative microscopic analysis. Significant inter-test discrepancies are observed. [less ▲]

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See detailEconomic evaluation of chronic hepatitis C treatment by interferon-ribavirin combination therapy in Belgium
Delwaide, Jean ULg

in Acta Gastro-Enterologica Belgica (2002), 65(4), 233-236

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response ... [more ▼]

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response is associated with long-term disappearance of the C virus, improvement of histology, improvement in quality of life and, most than likely, a reduction in the risk of premature death or infection-linked complications. This therapy is, however, expensive and the number of potentially treatable patients is high in view of the relatively high prevalence of the disease in the population. An economic evaluation is thus indispensable in order, on the one hand, to assess the cost-effectiveness ratio of the treatment (i.e. the extra cost to be paid for obtaining the greater effectiveness provided by the therapeutic combination in comparison with absence of treatment or treatment by interferon alone), and, on the other hand, to estimate practically the global cost of treatment for Belgium (i.e. the annual expense for society according to the number of patients treated per year). [less ▲]

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See detailPrevention de l'apparition du diabete de type 2 par l'inhibition du systeme renine-angiotensine.
Scheen, André ULg

in Revue Médicale de Liège (2002), 57(7), 449-52

Type 2 diabetes mellitus and arterial hypertension are part of the insulin resistance syndrome. Besides a metabolic component, insulin resistance has also an haemodynamic component, especially in relation ... [more ▼]

Type 2 diabetes mellitus and arterial hypertension are part of the insulin resistance syndrome. Besides a metabolic component, insulin resistance has also an haemodynamic component, especially in relation with an endothelial dysfunction. Some studies suggested that inhibitors of angiotensin converting enzyme can improve insulin sensitivity. Interestingly enough, three clinical trials recently reported concordant results showing that the inhibition of the renin-angiotensin system significantly reduces the risk of developing type 2 diabetes in patients at high risk of vascular complications, essentially with hypertension: the CAPPP trial with captopril (-14%, p = 0.39), the HOPE study with ramipril (-34%, p < 0.001) and the LIFE study with losartan (-25%, p < 0.001). However, these observations could be criticized because such a protective effect was only considered as a secondary endpoint in these studies. Two large prospective, controlled, randomized, double-blind trials are ongoing to specifically confirm this interesting hypothesis, one with ramipril and the other with valsartan. [less ▲]

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See detailEuropean guidelines for the management of low back pain
Van Tulder, M.; Kovacs, F.; Müller, G. et al

in Acta Orthopaedica Scandinavica. Supplement (2002), 73((Suppl 305)), 20-25

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See detailQuels espoirs de remyélinisation dans la sclérose en plaques ?
Rogister, Bernard ULg; Wislet, Sabine ULg; Belachew, Shibeshih ULg

in Agenda Psychiatrie (L') (2002), 24

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See detailAdult mullerian duct or utricle cyst: clinical significance and therapeutic management of 65 cases.
Coppens, Luc ULg; Bonnet, Pierre ULg; Andrianne, Robert ULg et al

in Journal of Urology (The) (2002), 167(4), 1740-4

PURPOSE: We define guidelines for the exploration and treatment of adult mullerian duct cysts. MATERIALS AND METHODS: From January 1988 through September 1999 a diagnosis of enlarged prostatic utricle was ... [more ▼]

PURPOSE: We define guidelines for the exploration and treatment of adult mullerian duct cysts. MATERIALS AND METHODS: From January 1988 through September 1999 a diagnosis of enlarged prostatic utricle was made in 65 adults based on transrectal ultrasound findings. Echographic criteria to define simple versus complicated cysts were detailed. We reviewed the clinical presentation, diagnostic modalities, indications for invasive procedures and postoperative outcome. RESULTS: The usual clinical presentations were hematospermia in 40% of cases, other ejaculatory disturbances in 20%, recurrent testicular or pelviperineal pain in 33%, lower urinary tract irritation symptoms in 25%, lower urinary tract infection in 18.5%, male infertility in 12% and incidental finding in 18.5%. Cyst dimensions did not influence the indication for invasive procedures, which were performed in only 27 of the 65 patients (41.5%) to treat disabling symptoms in 28% and obstructive infertility in 5%, and investigate complicated cysts on transrectal ultrasound in 6%. These procedures included transperineal or transrectal puncture in 9 patients, simple endoscopic section of the utricle meatus in 12 and large marsupialisation in 6. Complete and sustained cure was noted in half of the patients treated with cyst puncture only, although echographic relapse was the rule. Endoscopic procedures definitely improved or cured 82% of the patients at a mean followup of 51 months, during which neither early nor late complications were noted. CONCLUSIONS: Since almost 60% of adults diagnosed with a mullerian duct cyst did not experience any cyst related symptoms or ejaculatory-fertility impairment, we recommend that investigation and/or treatment should only be done in symptomatic or infertile patients. [less ▲]

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See detailPseudomonas aeruginosa displays an epidemic population structure.
Pirnay, Jean-Paul; De Vos, Daniel; Cochez, Christel et al

in Environmental microbiology (2002), 4(12), 898-911

Bacteria can have population structures ranging from the fully sexual to the highly clonal. Despite numerous studies, the population structure of Pseudomonas aeruginosa is still somewhat contentious. We ... [more ▼]

Bacteria can have population structures ranging from the fully sexual to the highly clonal. Despite numerous studies, the population structure of Pseudomonas aeruginosa is still somewhat contentious. We used a polyphasic approach in order to shed new light on this issue. A data set consisting of three outer membrane (lipo)protein gene sequences (oprI, oprL and oprD), a DNA-based fingerprint (amplified fragment length polymorphism), serotype and pyoverdine type of 73 P. aeruginosa clinical and environmental isolates, collected across the world, was analysed using biological data analysis software. We observed a clear mosaicism in the results, non-congruence between results of different typing methods and a microscale mosaic structure in the oprD gene. Hence, in this network, we also observed some clonal complexes characterized by an almost identical data set. The most recent clones exhibited serotypes O1, 6, 11 and 12. No obvious correlation was observed between these dominant clones and habitat or, with the exception of some recent clones, geographical origin. Our results are consistent with, and even clarify, some seemingly contradictory results in earlier epidemiological studies. Therefore, we suggest an epidemic population structure for P. aeruginosa, comparable with that of Neisseria meningitidis, a superficially clonal structure with frequent recombinations, in which occasionally highly successful epidemic clones arise. [less ▲]

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See detailImpact of closed habitat on the entomological diversity and abundance in carrot open fields
Colignon, Pierre; Gaspar, Charles; Haubruge, Eric ULg et al

in Med. Fac. Landbouw. Univ. Gent (2002), 67(3), 481-486

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See detailIdentités et transactions réflexives. Une approche de l'identité des acteurs retraités
Vrancken, Didier ULg

in Recherches Sociologiques et Anthropologiques (2002), 2

A partir de l'identification d'une population, celle des retraités âgés entre 50 et 75 ans, population particulièrement confrontée à des problèmes de reconnaissance et d'identités sociales, cet article ... [more ▼]

A partir de l'identification d'une population, celle des retraités âgés entre 50 et 75 ans, population particulièrement confrontée à des problèmes de reconnaissance et d'identités sociales, cet article propose de repenser le concept d'identité en sociologie au départ d'un triple travail d'articulation identitaire qu'accomplirait l'acteur. Après avoir identifié une transaction narrative, une transaction argumentative, l'auteur dégage une troisième forme : celle de la tradition réflexive analysée à la suite de la tradition expressiviste allemande et de son dépassement par la critique herméneutique. C'est de cette triple articulation identitaire que rendrait compte une typologie proposée en conclusion. [less ▲]

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See detailL'image du mois. Une onychopathie ponctuée en dé a coudre.
Perotti-Abad, M. J.; Arrese Estrada, Jorge ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(3), 129-30

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See detailBlood oxygen binding in hypoxaemic calves
Cambier, Carole ULg; Clerbaux; Detry, Bruno et al

in Veterinary Research (2002), 33(3), 283-290

Blood oxygen transport and tissue oxygenation were studied in 28 calves from the Belgian White and Blue breed (20 healthy and 8 hypoxaemic ones). Hypoxaemic calves were selected according to their high ... [more ▼]

Blood oxygen transport and tissue oxygenation were studied in 28 calves from the Belgian White and Blue breed (20 healthy and 8 hypoxaemic ones). Hypoxaemic calves were selected according to their high respiratory frequency and to their low partial oxygen pressure (PaO2) in the arterial blood. Venous and arterial blood samples were collected, and 2,3-diphosphoglycerate, adenosine triphosphate, chloride, inorganic phosphate and hemoglobin concentrations, and pH, PCO, and PO2 were determined. An oxygen equilibrium curve (OEC) was measured in standard conditions, for each animal. The arterial and venous OEC were calculated, taking body temperature, pH and PCO2 values in arterial and venous blood into account. The oxygen exchange fraction (OEF%), corresponding to the degree of blood desaturation between the arterial and the venous compartments, and the amount of oxygen released at the tissue level by 100 mL of blood (OEF Vol%) were calculated from the arterial and venous OEC combined with the PO2 and hemoglobin concentration. In hypoxaemic calves investigated in this study, the hemoglobin oxygen affinity, measured under standard conditions, was not modified. On the contrary, in vivo acidosis and hypercapnia induced a decrease in the hemoglobin oxygen affinity in arterial blood, which combined to the decrease in PaO2 led to a reduced hemoglobin saturation degree in the arterial compartment. However, this did not impair the oxygen exchange fraction (OEF%), since the hemoglobin saturation degree in venous blood was also diminished. [less ▲]

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See detailLa guerre et la médecine d'une culture de paix. 4. Synopsis des armes nucléaires.
Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(2), 107-12

The nuclear weapons have a terrifying power of devastation. A civilian nuclear accident has its own dramatic consequences. Both situations are, however, totally distinct with regard to medical ... [more ▼]

The nuclear weapons have a terrifying power of devastation. A civilian nuclear accident has its own dramatic consequences. Both situations are, however, totally distinct with regard to medical consequences. The Gulf war and Balkan war syndromes might be in part caused by uranium used in conventional amunitions. The risk of nuclear terrorism is an emerging eventuality. [less ▲]

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See detailMons/Maisières : nouvelle occupation paléolithique au site de Maisières-Canal
Miller, Rebecca ULg; Guillaume, Alain; Otte, Marcel ULg

in Chronique de l'Archéologie Wallonne (2002), 10

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See detailPhénomènes karstiques fossiles et actuels au sein des formations métamorphiques silico-alumineuses de la nappe pan-africaine de Yaoundé (Sud-Cameroun)
Vicat, Jean-Paul; Mvondoc, Henri; Willems, Luc ULg et al

in Comptes Rendus de l'Académie des Sciences. Série II, Mécanique, Physique, Chimie, Sciences de l'Univers, Sciences de la Terre (2002), 334

Fossil and present-time karstic phenomena in silico-aluminous metamorphic formations of the Pan-African nappe of Yaoundé (South-Cameroon). Numerous karstic features have been recognised in the non ... [more ▼]

Fossil and present-time karstic phenomena in silico-aluminous metamorphic formations of the Pan-African nappe of Yaoundé (South-Cameroon). Numerous karstic features have been recognised in the non-carbonaceous micaschists and gneisses of the Yaoundé Pan-African nappe, south of Cameroon. It is shown that their formation was controlled by the structural features of the rocks. The wells and the pipes in the bedrock outcrops point out a current karstification process, resulting from the plagioclase dissolution by the acid rain waters. Hill wall alveoli and caves, of pre-Miocene age, are exhumed features that were done by dissolution in the aquiferous underground. [less ▲]

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See detailPour une sémiologie historique de l'acte photographique
Havelange, Carl ULg

in Revue de la Faculté des Lettres d'El Jadida (2002)

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See detailInteraction of an odorant lactone with model phospholipid bilayers and its strong fluidizing action in yeast membrane.
Aguedo, Mario ULg; Beney, Laurent; Wache, Yves et al

in International journal of food microbiology (2002), 80(3), 211-5

Some odorant lactones are naturally present in fruits or in fermented products; they can also be used as food additives and can be produced by microorganisms at the industrial scale by biotechnological ... [more ▼]

Some odorant lactones are naturally present in fruits or in fermented products; they can also be used as food additives and can be produced by microorganisms at the industrial scale by biotechnological processes. Gamma-decalactone was previously shown to have antimicrobial properties. We determined by infrared spectroscopy measurements that this compound rapidly diffused into model phospholipid bilayers (within 2 min), modifying the general physical state of a dimyristoyl-L-alpha-phosphatidylcholine (DMPC) film. In vivo, the lactone strongly increased membrane fluidity in the model yeast Yarrowia lipolytica, as evaluated by fluorescence anisotropy measurements. This effect was more important than that of benzyl alcohol, which is known as a fluidizing agent in living cells, and may explain the toxic action of gamma-decalactone in microorganisms. [less ▲]

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See detailComprendre et prévenir la violence à l'école : vers un référentiel critique des mesures actuelles de prévention et de lutte contre la violence scolaire
Munten, Jacqueline; Jardon, Dorothée; Mouvet, Bernadette ULg

in Point sur la Recherche en Education (Le) (2002), 22

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See detailResults of a whole genome scan targeting QTL for growth and carcass traits in a Pietrain x Large White intercross
Nezer, C.; Moreau, L.; Wagenaar, D. et al

in Genetics, Selection, Evolution (2002), 34(3, May-Jun), 371-387

We herein report the results of a whole genome scan performed in a Pietrain x Large White intercross counting 525 offspring to map QTL influencing economically important growth and carcass traits. We ... [more ▼]

We herein report the results of a whole genome scan performed in a Pietrain x Large White intercross counting 525 offspring to map QTL influencing economically important growth and carcass traits. We report experiment-wide significant lod scores (> 4.6) for meatiness and fat deposition on chromosome SSC2, and for average daily gain and carcass length on chromosome SSC7. Additional suggestive lod scores (> 3.3) for fat deposition are reported on chromosomes SSC1, SSC7 and SSC13. A significant dominance deviation was found for the QTL on SSC1, while the hypothesis of an additive QTL could not be rejected for the QTL on SSC7 and SSC13. No evidence for imprinted QTL could be found for QTL other than the one previously reported on SSC2. [less ▲]

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See detailInstrumental non-invasive assessments of cosmetic efficacy.
Pierard, Gérald ULg

in Journal of Cosmetic Dermatology (2002), 1(2), 57-8

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See detailA transformed fish cell line expressing a green fluorescent protein-luciferase fusion gene responding to cellular stress
Molina, A.; Carpeaux, Rudy ULg; Martial, Joseph ULg et al

in Toxicology in Vitro (2002), 16(2), 201-7

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein ... [more ▼]

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein (GFP)-luciferase fusion protein, was assessed by measuring the luciferase enzymatic activity by luminometry and the GFP expression by fluorescence microscopy and flow cytometry. The clone was characterized for its capacity to respond to heat shock treatment. The results show high induction after 1 h at 37 degrees C of treatment, up to 500-fold. In addition, its convenience to detect a large range of cellular stressors was evaluated. We observed high induction when Cd2+, Zn2+, Hg2+ or Cu2+ was added, but not Pb2+. In addition, activation of the reporter gene was observed in the presence of other compounds such as acetyl chloride, tetrachlorophenol, chloroacetamide and sodium arsenite. In conclusion, this cell line can be used as a rapid, cheap and easy biological test to determine cellular stress induced by environmental pollutants, alone or in conjunction with other, more specific assays. [less ▲]

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See detailRéplication, clivage-encapsidation et recombinaison de l'ADN des herpèsvirus
Schynts, Frédéric; Meurens, François; Muylkens, Benoît ULg et al

in Virologie (2002), 6

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See detailRole Of The Somatotropic Axis In The Mammalian Metabolism
Renaville, Robert ULg; Hammadi, M.; Portetelle, Daniel ULg

in Domestic Animal Endocrinology (2002), 23(1-2),

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See detailNew in situ generated ruthenium catalysts bearing N-heterocyclic carbene ligands for the ring-opening metathesis polymerization of cyclooctene
Delaude, Lionel ULg; Szypa, Magdalena; Demonceau, Albert ULg et al

in Advanced Synthesis & Catalysis (2002), 344(6-7), 749-756

New 1,3-diarylimidazol(in)ium chlorides bearing phenyl, 1-naphthyl, 4-biphenyl, 2-tolyl, 2,6-dimethylphenyl, and 3,5-dimethylphenyl substituents were synthesized. They were combined with [RuCl2 (p-cymene ... [more ▼]

New 1,3-diarylimidazol(in)ium chlorides bearing phenyl, 1-naphthyl, 4-biphenyl, 2-tolyl, 2,6-dimethylphenyl, and 3,5-dimethylphenyl substituents were synthesized. They were combined with [RuCl2 (p-cymene)](2) and potassium tert-butoxide or sodium hydride to generate the corresponding ruthenium-N-heterocyclic carbene complexes in situ. Catalyst precursors derived from imidazol(in)ium salts bearing the 2,4,6-trimethylphenyl (mesityl) and the 2,6-diisopropylphenyl groups were also prepared. The catalytic activity of all these species in the photoinduced ring-opening metathesis polymerization of cyclooctene was investigated. The C4-C5 double bond in the imidazole ring of the N-heterocyclic carbene ligands was not crucial to achieve high catalytic efficiencies. The presence or the absence of alkyl groups on the ortho positions of the phenyl rings had a more pronounced influence. Blocking all the ortho positions was a requisite for obtaining efficient catalysts. Failure to do so probably results in the ortho-metallation of the carbene ligand, thereby altering the coordination sphere of the ruthenium active centers. [less ▲]

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See detailEnzymatically prepared n-alkyl esters of glucuronic acid: The effect of hydrophobic chain length on surface properties
Blecker, Christophe ULg; Piccicuto, S.; Lognay, Georges ULg et al

in Journal of Colloid & Interface Science (2002), 247(2), 424-428

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and ... [more ▼]

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and equilibrium surface tension are presented for esters with octyl, decyl, dodecyl, and tetradecyl alkyl segments. Increasing the alkyl chain length has a significant influence on the surface activity. Decyl and dodecyl glucuronate exhibit an interesting adsorption speed associated with foaming capacity. Octyl glucuronate exhibits a micellar organization as its bulk concentration is over 10.68 mM. (C) 2002 Elsevier Science (USA). [less ▲]

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See detailMerits of the multivariate Dale model in genetic association studies
Van Steen, Kristel ULg; Molenberghs, G.; Tahri, N.

in Genetic Epidemiology (2002), 23

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See detailCaractérisation physico-chimique de gommes végétales exsudées par quelques acacias du Burkina Faso
Djiré, O.; Ntema, P.; Zgoulli, S. et al

in Science et Technique (2002), 25(2), 37-47

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See detailModeling [F-18]MPPF positron emission tomography kinetics for the determination of 5-hydroxytryptamine(1A) receptor concentration with multiinjection
Costes, Nicolas; Merlet, I.; Zimmer, L. et al

in Journal of Cerebral Blood Flow & Metabolism (2002), 22

The selectivity of [F-18]MPPF (fluorine-18-labeled 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pirydynyl)-p-fluorobenzamido]ethylpiperazine) for serotonergic 5-hydroxytryptamine(1A) (5-HT1A) receptors has been ... [more ▼]

The selectivity of [F-18]MPPF (fluorine-18-labeled 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pirydynyl)-p-fluorobenzamido]ethylpiperazine) for serotonergic 5-hydroxytryptamine(1A) (5-HT1A) receptors has been established in animals and humans. The authors quantified the parameters of ligand-receptor exchanges using a double-injection protocol. After injection of a tracer and a coinjection dose of [F-18]MPPF, dynamic positron emission tomography (PET) data Were acquired during a 160-minute session in five healthy males. These PET and magnetic resonance imaging data were coregistered for anatomical identification. A three-compartment model was used to determine six parameters: F-v (vascular fraction). K-1, k(2) (plasma/free compartment exchange rate). k(off). k(on)/V-r (association and dissociation rate), B-max (receptor concentration), and to deduce K-d (apparent equilibrium dissociation rate). The model was fitted with regional PET kinetics and arterial input function corrected for metabolites. Analytical distribution volume and binding potential Were compared With indices generated by Logan-Patlak graphical analysis. The 5HT(1A) specificity for MPPF was evidenced. A B-max of 2.9 pmol/mL and a K-d of 2.8 nmol/L were found in hippocampal regions, K-d and distribution volume in the free compartment were regionally stable. and the Logan binding potential was linearly correlated to B-max. This study confirms the value of MPPF in the investigation of normal and pathologic systems involving the limbic network and 5-HT1A receptors. Standard values can be used for the simulation of simplified protocols. [less ▲]

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See detailSubcellular Localization Of The Bovine Leukemia Virus R3 And G4 Accessory Proteins
Lefebvre, Laurent; Ciminale, Vincenzo; Vanderplasschen, Alain ULg et al

in Journal of Virology (2002), 76(15), 7843-7854

Bovine leukemia virus (BLV) is a complex retrovirus that belongs to the Deltaretrovirus genus, which also includes Human T-cell leukemia virus type 1 (HTLV-1). Both viruses contain an X region coding for ... [more ▼]

Bovine leukemia virus (BLV) is a complex retrovirus that belongs to the Deltaretrovirus genus, which also includes Human T-cell leukemia virus type 1 (HTLV-1). Both viruses contain an X region coding for at least four proteins: Tax and Rex, which are involved in transcriptional and posttranscriptional regulation, respectively, and the accessory proteins R3 and G4 (for BLV) and p12(I), p13(II), and p30(II) (for HTLV-1). The present study was aimed at characterizing the subcellular localization of BLV R3 and G4. The results of immunofluorescence experiments on transfected HeLa Tat cells demonstrated that R3 is located in the nucleus and in cellular membranes, as previously reported for HTLV-1 p12(1). In contrast, G4, like p13(II), is localized both in the nucleus and in mitochondria. In addition, we have shown that G4 harbors a mitochondrial targeting signal consisting of a hydrophobic region and an amphipathic alpha-helix. Thus, despite a lack of significant primary sequence homology, R3 and p12(1) and G4 and p13(II) exhibit similar targeting properties, suggesting possible overlap in their functional properties. [less ▲]

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See detailResponses and adaptations of Episyrphus balteatus and Adalia bipunctata to allelochemicals from Brassicaceae plant through their preys
Vanhaelen, Nicolas; Haubruge, Eric ULg; Gaspar, Charles et al

in International Symposium on Ecology of Aphidophaga (2002)

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See detailEvolution des donnees maternelles et perinatales recueillies en routine entre 1980 et 1998 a la maternite de reference de Rutshuru en Republique democratique du congo. Deces maternels et interventions obstetricales.
Mugisho, Etienne; Dramaix, Michele; Porignon, Denis ULg et al

in Sante (Montrouge, France) (2002), 12(2), 247-51

This report is the first of 2 papers that analyse data routinely collected in the maternity ward of Rutshuru (democratic Republic of Congo). The present work describes the evolution of caesarean section ... [more ▼]

This report is the first of 2 papers that analyse data routinely collected in the maternity ward of Rutshuru (democratic Republic of Congo). The present work describes the evolution of caesarean section, maternal deaths and the associated risk factors. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were collected. Characteristics, mortality, morbidity of mothers and new-borns and obstetrical interventions were recorded. The statistical analyses applied included khi2, t-test, simple linear and multiple logistic regression. RESULTS: Fifteen percent had a caesarean section and 1.9% of women died. When referred to the expected births during the period, these numbers led to a ratio of 150 maternal deaths for 100,000 expected births and a ratio of caesarean section of 1.2%. At admission, 35% of the women presented at least one of the four risk factors used for reference. The proportion of women with at least one of the 4 risk factors went up from 26.1% to 39.5%. The proportion of caesarean sections went up from 1.9% to 34.1%. The proportion of maternal deaths remained constant except in 1988, 1994, 1995 and 1997. Three of the four reference factors, the Baudeloque diameter, parity and height were associated with caesarean section. Age only was associated with maternal death. Education and marital status were both associated with caesarean section and maternal death. CONCLUSION: This analysis shows high levels of maternal mortality and caesarean section. The authors recommend to analyse on a larger scale the value of the reference factors used in antenatal services and to standardise indications for the different obstetrical interventions. [less ▲]

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See detailHow to substantiate eradication of bovine brucellosis when aspecific serological reactions occur in the course of brucellosis testing.
Godfroid, Jacques; Saegerman, Claude ULg; Wellemans, Vincent et al

in Veterinary Microbiology (2002), 90(1-4), 461-77

Collaborative work was financed by the EU to develop and assess new diagnostic tools that can differentiate between bovine brucellosis and bovine infections due to Yersinia enterocolitica O:9 either in ... [more ▼]

Collaborative work was financed by the EU to develop and assess new diagnostic tools that can differentiate between bovine brucellosis and bovine infections due to Yersinia enterocolitica O:9 either in conjunction with, or as an alternative to, the classical serological, bacteriological or allergic skin tests. Sixteen heifers were experimentally infected with Brucella abortus biovar 1 (five heifers), Brucella suis biovar 2 (two heifers), Y. enterocolitica O:9 (six heifers) and Y. enterocolitica O:3 (three heifers). Four heifers, naturally infected with Y. enterocolitica O:9 that presented aspecific brucellosis serological reactions were also included in the experiment. A self-limited infection was induced in cattle by B. suis biovar 2. All the brucellosis serological tests used, i.e. the slow agglutination test (SAW), the Rose Bengal test (RB), the complement fixation test (CFT), indirect and competitive ELISA's, lacked specificity when used to analyze sera from Y. enterocolitica O:9 infected animals. A Yersinia outer membrane proteins (YOPs)-ELISA was also used and although the test is able to detect a Yersinia group infection, it provided no evidence of whether or not there is a possible brucellosis infection when dual infections are present. The brucellergen IFN-gamma test showed a lack of specificity also. The only test that was proven to be specific is the brucellergen skin test. All brucellosis serological tests, except the indirect ELISA, were limited in their ability to detect B. abortus persistently infected animals. Based on these experimental studies, a strategy was implemented as part of the year 2001 Belgian Brucellosis Eradication Program to substantiate the eradication of bovine brucellosis. Epidemiological inquiries have identified risk factors associated with aspecific serological reactions, possible transmission and infection of cattle by B. suis biovar 2 from infected wild boars; and both legal and administrative measures taken by the veterinary services. No cases of bovine brucellosis have been confirmed in Belgium since March 2000. [less ▲]

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See detailExamen critique de l'étymologie de brasser
Boutier, Marie-Guy ULg

in Dialectes de Wallonie (2002), 29-30

La filiation traditionnellement établie entre gaulois brace "matière servant à préparer la bière" (dont provient fr. brais) et fr. brasser "préparer la bière" est réexaminée dans cet article par l'examen ... [more ▼]

La filiation traditionnellement établie entre gaulois brace "matière servant à préparer la bière" (dont provient fr. brais) et fr. brasser "préparer la bière" est réexaminée dans cet article par l'examen de l'ensemble du vocabulaire technologique wallon de la brasserie et des réalités concrètes qui sont désignées: la préparation du brais, d'une part; le brassage de la bière, d'autre part. [less ▲]

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See detailHamstring muscle strain recurrence and strength performance disorders
Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg; Namurois, Marie-Hélène ULg et al

in American Journal of Sports Medicine (2002), 30(2, Mar-Apr), 199-203

We determined the frequency of strength disorders in 26 athletes with a history of hamstring muscle injury and recurrent strains and discomfort. We also assessed the effectiveness of rehabilitation to ... [more ▼]

We determined the frequency of strength disorders in 26 athletes with a history of hamstring muscle injury and recurrent strains and discomfort. We also assessed the effectiveness of rehabilitation to correct muscle performance. After concentric and eccentric isokinetic assessment, 18 athletes were found to have strength deficits, as determined by statistically selected cutoffs of peak torque, bilateral differences, and the flexors/quadriceps ratio. The discriminating character of the eccentric trial was demonstrated, combining a preferential eccentric peak torque deficit and a significant reduction of the mixed eccentric flexors/concentric quadriceps ratio. The athletes with muscle imbalances followed a rehabilitation program individually adapted from their strength profile. Treatment length was from 10 to 30 sessions and resulted in isokinetic parameter normalization in 17 of 18 subjects. Isokinetically corrected subjects were observed for 12 months after return to athletics. None sustained a clinically diagnosed hamstring muscle reinjury. Subjective intensity of pain and discomfort were significantly reduced, and they all returned to their prior level of competition. These results demonstrate that persistent muscle strength abnormalities may give rise to recurrent hamstring injuries and discomfort. An individualized rehabilitation program emphasizing eccentric training based on specific deficits contributes to a decrease in symptoms on return to sports. [less ▲]

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See detailCa2+/calmodulin dependent protein kinase regulates GABA activated Cl- current in cockroach dorsal unpaired median neurons
Alix, Philippe ULg; Grolleau, F; Hue, B

in Journal of Neurophysiology (2002), 87

We studied gamma-aminobutyric acid (GABA)-mediated currents in short-term cultured dorsal unpaired median (DUM) neurons of cockroach Periplaneta americana using the whole cell patch-clamp technique in ... [more ▼]

We studied gamma-aminobutyric acid (GABA)-mediated currents in short-term cultured dorsal unpaired median (DUM) neurons of cockroach Periplaneta americana using the whole cell patch-clamp technique in symmetrical chloride solutions. All DUM neurons voltage-clamped at -50 mV displayed inward currents (I(GABA)) when 10(-4) M of GABA was applied by pneumatic pressure-ejection pulses. The semi-logarithmic curve of I(GABA) amplitude versus the ejection time yielded a Hill coefficient of 4.0. I(GABA) was chloride (Cl-) because the reversal potential given by the current-voltage (I-V) curve varied according to the value predicted by the Nernst equation for Cl- dependence. In addition, I(GABA) was almost completely blocked by bath application of the chloride channel blockers picrotoxin (PTX) or 3,3-bis(trifluoromethyl)bicyclo-[2,2,1]heptane-2,2-diacarbonitrile (BIDN). The I-V curve for I(GABA) displayed a unexpected biphasic aspect and was best fitted by two linear regressions giving two slope conductances of 35.6 +/- 2.1 and 80.9 +/- 4.1 nS for potentials ranging from 0 to -30 and -30 to -70 mV, respectively. At -50 mV, the current amplitude was decreased by cadmium chloride (CdCl2, 10(-3) M) and calcium-free solution. The semi-logarithmic curve for CdCl2-resistant I(GABA) gave a Hill coefficient of 2.4. Hyperpolarizing voltage step from -50 to -80 mV was known to increase calcium influx through calcium-resting channels. According to this protocol, a significant increase of I(GABA) amplitude was observed. However, this effect was never obtained when the same protocol was applied on cell body pretreated with CdCl2. When the calmodulin blocker N-(6-aminohexyl)-5-chloro-1-naphtalene-sulfonamide or the calcium-calmodulin-dependent protein kinase blocker 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine (KN-62) was added in the pipette solution, I(GABA) amplitude was decreased. Pressure ejection application of the cis-4-aminocrotonic acid (CACA) on DUM neuron cell body held at -50 mV, evoked a Cl- inward current which was insensitive to CdCl2. The Hill plot yielded a Hill coefficient of 2.3, and the I-V curve was always linear in the negative potential range with a slope conductance of 32.4 +/- 1.1 nS. These results, similar to those obtained with GABA in the presence of CdCl2 and KN-62, indicated that CACA activated one subtype of GABA receptor. Our study demonstrated that at least two distinct subtypes of Cl--dependent GABA receptors were expressed in DUM neurons, one of which is regulated by an intracellular Ca2+-dependent mechanism via a calcium-dependent protein kinase. The consequences of the modulatory action of Ca2+ in GABA receptors function and their sensitivity to insecticide are discussed. [less ▲]

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See detailPosidonia Oceanica Meadow: A Low Nutrient High Chlorophyll (LNHC) System?
Gobert, Sylvie ULg; Laumont, N.; Bouquegneau, Jean-Marie ULg

in BMC Ecology (2002), 2

BACKGROUND: In spite of very low nutrient concentrations in its vicinity - both column and pore waters-, the Posidonia oceanica of the Revellata Bay displays high biomass and productivity. We measured the ... [more ▼]

BACKGROUND: In spite of very low nutrient concentrations in its vicinity - both column and pore waters-, the Posidonia oceanica of the Revellata Bay displays high biomass and productivity. We measured the nutrient fluxes from the sediment into the water enclosed among the leaf shoots ("canopy water") to determine if it is possible source of nutrients for P. oceanica leaves. RESULTS: During the summer, the canopy water appears to act as a nutrient reservoir for the plant. During that period, the canopy water layer displays both a temperature 0.5 degrees C cooler than the upper water column, and a much higher nutrient content, as shown in this work using a very simple original technique permitting to sample water with a minimal disturbance of the water column's vertical structure.Despite low nutrient concentrations in pore water, mean net fluxes were measured from the sediment to the canopy water. These fluxes are sufficient to provide 20% of the mean daily nitrogen and phosphorus requirement of the P. oceanica shoots. CONCLUSION: An internal cycling of nutrients from P. oceanica senescent leaves was previously noted as an efficient strategy to help face low nutrient availability. The present study points out a second strategy which consists in holding back, in the canopy, the nutrients released at the water-sediment interface. This process occurs when long leaves, during poor nutrient periods in the water column, providing, to P. oceanica, the possibility to develop, high biomass, high chlorophyll quantities in low nutrient environment (a Low Nutrients High Chlorophyll system). [less ▲]

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See detailPISA : une enquête en suspicion légitime
Dumortier, Jean-Louis ULg

in Lettre de la DFLM (2002), 30

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See detailSternal recumbency or suspension by the hind legs immediately after delivery improves respiratory and metabolic adaptation to extra uterine life in newborn calves delivered by caesarean section.
Uystepruyst, Christophe; Coghe, Joost; Dorts, Thierry et al

in Veterinary Research (2002), 33(6), 709-724

The aim of this study was to evaluate the effect of body positioning immediately after delivery on respiratory and metabolic adaptation to extra-uterine life in newborn calves. One hundred and one Belgian ... [more ▼]

The aim of this study was to evaluate the effect of body positioning immediately after delivery on respiratory and metabolic adaptation to extra-uterine life in newborn calves. One hundred and one Belgian White and Blue calves were delivered at term by an elective caesarean section and were assigned into three categories according to the body position imposed immediately after umbilical cord rupture: 71 calves were placed in lateral recumbency; 16 calves were placed in sternal recumbency and 14 calves were suspended by the hind legs for less than 90 seconds (75 +/- 5 s). Following this initial body position, the calves were allowed to move without restraint. They were examined at birth, 5, 15, 30, 45 and 60 minutes, and 2, 3, 6, 12 and 24 hours after birth by the following measurements: physical examination, heart rate, arterial blood gas analysis, pulmonary function tests using the esophageal balloon catheter technique, arterial and venous blood acid-base balance analysis, rectal temperature, jugular venous blood sampling for the determination of blood glucose, plasma lactate and serum cortisol concentrations, haematologic variables and passive immune transfer variables. Body positioning immediately after delivery clearly influenced respiratory and metabolic adaptation to extra-uterine life in term calves delivered by an elective caesarean section. Systematic sternal recumbency and suspension by the hind legs for less than 90 seconds immediately after umbilical cord rupture had a positive functional impact on postnatal pulmonary mechanics and gas exchange and on postnatal correction of mixed acidosis present at birth, contributing in turn to an enhanced passive immune transfer. These two body positions should be encouraged to improve adaptation at birth in healthy term calves delivered by an elective caesarean section. Evaluation of possible side-effects is required before application in severely asphyxiated calves. [less ▲]

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See detailRegelgeving inzake het zelfbeschikkingsrecht, Redactie Privaat
Leleu, Yves-Henri ULg

in Tijdschrift voor Privaatrecht (2002)

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See detailNormative and psychometric data from the Body Image Assessment - Revised in a population of french-speaking women
Bragard, Isabelle ULg; Mayers, I.; Demoulin, Catherine et al

in Psychologica Belgica (2002), 42(4), 227-249

This article concerns the creation of norms and the validation in French of the Body Image Assessment – Revised (BIA-R; Beebe, Holmbeck, & Grzeskiewicz, 1999). The sample comprised 100 normal female ... [more ▼]

This article concerns the creation of norms and the validation in French of the Body Image Assessment – Revised (BIA-R; Beebe, Holmbeck, & Grzeskiewicz, 1999). The sample comprised 100 normal female subjects. They completed questionnaires assessing body experience, eating pathology, psychological functioning, general perception and the BIA-R (Beebe et al., 1999). This test consists of nine silhouettes from which the subject has to choose the somatotype corresponding to her actual shape (cognitive response), the way she feels (affective response) and the way she would like to look (optative response). The results show a good concurrent validity for the cognitive and affective indices and the affective/ cognitive vs. optative divergences. On the other hand, we were not able to demonstrate such validity for the optative index and the affective vs. cognitive divergence index [less ▲]

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See detailEvidence of an equilibrium between selenides and osmium(VIII) reagents and selenoxides and osmium(VI) reagents
Krief, A.; Destree, A.; Durisotti, V. et al

in Chemical Communications (2002), (6), 558-559

Driving the equilibrium between selenides and osmium( VIII) reagents with selenoxides and osmium( VI) by a subsequent reaction (rearrangement of allyl selenoxides to allyl alcohols or addition of osmium ... [more ▼]

Driving the equilibrium between selenides and osmium( VIII) reagents with selenoxides and osmium( VI) by a subsequent reaction (rearrangement of allyl selenoxides to allyl alcohols or addition of osmium( VIII) species on C C double bonds) to one side, allows the transformation of methyl geranyl selenides to linalool and of methyl citronellyl selenoxide to 6,7-dihydroxy citronellyl selenide. [less ▲]

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See detailDHEA et intracrinologie de jouvence pour la peau? Entre raison et magie.
Bourguignon, Raphael; Uhoda, I.; Henry, Frédérique ULg et al

in Revue Médicale de Liège (2002), 57(7), 438-42

Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In ... [more ▼]

Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In the skin, sebaceous glands enlarge and seborrhoea increases in post-menopausal women. No other effect is clinically discernable on the skin. At this level, DHEA does not show efficacy comparable to that of other anti-ageing compounds. [less ▲]

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See detailCurrent treatments of muco-cutaneous herpes simplex virus infections
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Current Medicinal Chemistry - Anti-Infective Agents (2002), 1(1), 83-98

Infection by Herpes Simplex Virus (HSV) types I and II represent a worldwide medical problem. After the primary infection the virus establishes a life-long latency in the dorsal root ganglia and ... [more ▼]

Infection by Herpes Simplex Virus (HSV) types I and II represent a worldwide medical problem. After the primary infection the virus establishes a life-long latency in the dorsal root ganglia and recurrences may occur at unpredictable times and rate. The most frequent clinical presentation of HSV infection is recurrent herpes labialis and herpes genitalis. The clinical expression varies according to the body site, the infected cell type, the relationship between HSV and the host immune status. Viral identification techniques such as immunohistochemistry and in situ hybridization on Tzanck smears and muco-cutanenous biopsies are helpful in the diagnosis of atypical cutaneous lesions. The treatment modalities of HSV infections include the reduction of viral load using antiviral agents, the non-specific immune stimulation of the host and specific vaccination in order to prevent new acquisition and to mitigate symptoms in already infected individuals. This review addresses various therapeutic options, their mode of action, and clinical value as well as the indications of the various drugs. [less ▲]

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See detailUne allergie conjugale exacerbée: les dermatoses par procuration.
Martalo, O.; Fraiture, A. L.; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2002), 57(5), 320-3

A young woman presented two distinct vesiculobullous dermatoses sharing in common her husband's imputability. She suffered from contact dermatitis due to colophony used by her husband who was violinist ... [more ▼]

A young woman presented two distinct vesiculobullous dermatoses sharing in common her husband's imputability. She suffered from contact dermatitis due to colophony used by her husband who was violinist. During her second pregnancy, pemphigoid gestationis was diagnosed. This autoimmune disease is directed to the father's HLA class II present on the placenta. The same antibodies also interact with the dermo-epidermal junction in the mother where they induce blisters. [less ▲]

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See detailSyndrome du canal lent associe a une translocation autosomique 2q31-9p27.
Zeevaert, Bernard ULg; Hansen, Isabelle ULg; Crielaard, Jean-Michel ULg et al

in Revue Neurologique (2002), 158(5 Pt 1), 605-8

A 27-year-old man complained of cervicoscapular and forearm weakness and amyotrophy. Electromyographic evaluation showed neuromuscular transmission dysfunction and a repetitive compound muscle action ... [more ▼]

A 27-year-old man complained of cervicoscapular and forearm weakness and amyotrophy. Electromyographic evaluation showed neuromuscular transmission dysfunction and a repetitive compound muscle action potential to a single stimulus. Prostigmine did not improve neuromuscular transmission. The genetic analysis of the patient's lymphocytes demonstrated a chromosomic 2q31-9p27 translocation. The combination of the clinical and electrophysiological data as well as the lack of auto-immunity signs against neuromuscular junction constituents led to the diagnosis to congenital postsynaptic myasthenic syndrome also called slow channel syndrome. This congenital myasthenic syndrome is for the first time associated with an autosomal translocation 2q31-9p27. [less ▲]

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See detailImage analysis characterization of highly oriented freeze-drying porous materials
Blacher, Silvia ULg; Maquet, Véronique; Jérôme, Robert ULg et al

in Image Analysis and Stereology (2002), 21

Image analysis has been used as a potential tool for the characterization of the texture of ultramacroporous foams prepared by freeze-drying. It has been shown that this technique actually provides ... [more ▼]

Image analysis has been used as a potential tool for the characterization of the texture of ultramacroporous foams prepared by freeze-drying. It has been shown that this technique actually provides valuable information on the structure of this kind of material. Image analysis of SEM micrographs of transverse sections at two different magnifications gave information on both the macroporosity (10 μm < width < 100 μm) and ultramacroporosity (width > 100 μm). Moreover, the foam anisotropy has been determined by image analysis of longitudinal sections. [less ▲]

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See detailIn vitro culture of immature embryos of Phaseolus polyanthus Greenm. and Phaseolus vulgaris L.
Toussaint, André ULg; Clément, F.; Mergeai, Guy ULg et al

in Annual Report of the Bean Improvment Cooperative (2002), 45

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See detailLes troubles morpho-syntaxiques développementaux en langage oral : quel cadre théorique adopter?
Maillart, Christelle ULg; Schelstraete, Marie-Anne; Hupet, Michel

in Langage et l'Homme (Le) : Recherches Pluridisciplinaires sur le Langage (2002), 37(2), 85-102

This article contrasts two theoretical frames actually used to account for morphosyntactic disorders in children with specific language impairment. The first one stems from a traditional formal linguistic ... [more ▼]

This article contrasts two theoretical frames actually used to account for morphosyntactic disorders in children with specific language impairment. The first one stems from a traditional formal linguistic account developped in the context of Chomsky’s works while the second approach, the emergent account, is more functional. Following the linguistic account, it has been assumed that children are born with an innate set of representational constraints, the Universal Grammar, on which grammars are possible for a given language. In contrast, for the emergentist view, it is not necessary to postulate an autonomous device that evolved for grammar rather language in general, and grammar in particular, would emerge from cognitive and communicative abilities and linguistic environment. Both theoretical frames are briefly presented and discussed as well as their implications for the pathology study in children. [less ▲]

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See detailUne dorsalgie malheureusement tenace
Malaise, Michel ULg; Kaye, Olivier; Radermecker, Maurice ULg et al

in Revue Médicale de Liège (2002), 57(5), 270-273

The etiological diagnosis of chronic thoracic pain is wide, from benign mechanical disorders to tumors. Reaching the exact diagnosis in often time consuming. Despite the availability of new techniques of ... [more ▼]

The etiological diagnosis of chronic thoracic pain is wide, from benign mechanical disorders to tumors. Reaching the exact diagnosis in often time consuming. Despite the availability of new techniques of imagery, a meticulous clinical history and physical examination remain mandatory. They will lead the exploration. Idiopathic intercostal neuralgia does not exist. [less ▲]

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See detailExercise-induced pulmonary perfusion redistribution in heaves
Harmegnies, N. F.; Duvivier, D. H.; Vandenput, Sandrina ULg et al

in Equine Veterinary Journal. Supplement (2002), 34(suppl), 478-484

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in ... [more ▼]

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in remission (B(I)) and during clinical signs of disease (B(II)) were investigated. Dimensions of the exercising pulmonary perfusion (QE) images were expressed in percent of the resting perfusion (QR) images. Computed QE to QR ratios (QE/QR) images enabled the definition of the region more perfused at exercise than at rest (R1). In all groups, exercise induced a major enlargement of the Q image but a larger increase of the lung height was found in 'heavey' horses. Compared to A, 'heavey' horses showed a larger R1 region with a significantly higher QE/QR. Location of R1 pointed out the dorsal lung region as a major site of pulmonary perfusion redistribution for all groups. This work demonstrated (1) the feasibility of using scintigraphy for studying exercise-induced pulmonary perfusion redistribution; (2) perfusion redistribution to the dorsal lung with exercise and (3) an intensified redistribution in 'heavey' horses, either clinically affected or not. [less ▲]

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See detailIsolement et caractérisation de l'ostéocalcine équine
Carstanjen, Bianca; Wattiez, R.; Amory, Hélène ULg et al

in Annales de Médecine Vétérinaire (2002), 146

Equine bone gamma-carboxyglutamic acid containing protein - also called osteocalcin - has been isolated for the first time till homogeneity. After acid demineralisation and acid extraction, the ... [more ▼]

Equine bone gamma-carboxyglutamic acid containing protein - also called osteocalcin - has been isolated for the first time till homogeneity. After acid demineralisation and acid extraction, the purification procedure was based on reverse phase chromatography, gel filtration and ion exchange chromatography. The amino acid sequence of the primary structure has been determined to be YLDHWLGA(HYP) APYPDPL(GLA)PRR(GLA)VC (GLA)LNPDCDELADHIGF-AYRRFYGPV. The protein has a calculated molecular weight of 5,732 kDa and a calculated isoelectric point of 4,45. It contains 49 amino acids, from which 3 are gamma-carboxyglutamic acid residues at position 17, 21 and 24 and has a fully hydroxylated proline in position nine and cysteine in position 23 and 29. Equine osteocalcin shows a strong homology with bovine (98%), ovine (96%) and human (94%) osteocalcin [less ▲]

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See detailInfo-congres. Essai de prevention du diabete de type 1 par le nicotinamide: les lecons positives d'un essai clinique negatif (ENDIT).
Philips, Jean-Christophe ULg; Scheen, André ULg

in Revue Médicale de Liège (2002), 57(10), 672-5

ENDIT ("European Nicotinamide Diabetes Intervention Trial") is a large placebo-controlled randomised clinical trial that aimed at studying the efficacy of nicotinamide in the prevention of type 1 diabetes ... [more ▼]

ENDIT ("European Nicotinamide Diabetes Intervention Trial") is a large placebo-controlled randomised clinical trial that aimed at studying the efficacy of nicotinamide in the prevention of type 1 diabetes mellitus among first-degree relatives of type 1 diabetic patients with positive islet cell antibodies (ICA). The results presented at the last congress of the European Association for the Study of Diabetes (EASD) in Budapest do not evidence any significant difference in the risk of developing overt diabetes mellitus in the patients treated with nicotinamide (n = 274) as compared to those receiving placebo (n = 275) after 5 years of follow-up. Despite these negative results, positive lessons could be drawn from ENDIT: 1) the feasibility of a large long-standing multicentre European trial in a difficult research area; 2) the importance of large randomised controlled clinical trials to bring the evidence requested by "Evidence-Based Medicine"; 3) the predictive value of various risk markers to progress toward type 1 diabetes in first-degree relatives, especially the number of positive auto-antibodies; and 4) the urgent need to continue intensive research in this important field of preventive medicine. [less ▲]

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See detailFactor XIII a-positive dermal dendrocytes and shear wave propagation in human skin.
Hermanns-Lê, Trinh ULg; Uhoda, I.; Pierard, Claudine ULg et al

in European Journal of Clinical Investigation (2002), 32(11), 847-51

BACKGROUND: The in vivo interdependence between the phenotypic characteristics of dermal cells and the strain imposed on the tissue has not been studied thoroughly in humans. In particular the mechanical ... [more ▼]

BACKGROUND: The in vivo interdependence between the phenotypic characteristics of dermal cells and the strain imposed on the tissue has not been studied thoroughly in humans. In particular the mechanical force modulation of Factor XIII a expression in dermal dendrocytes (DD) remains unknown. MATERIALS AND METHODS: The present study compares the numerical density of Factor XIII a-positive DD and the in vivo shear wave velocity in the skin. The investigation was performed in 20 men of normal weight and 20 obese men before and after entering a slimming process. RESULTS: Excess cutaneous fat places the skin under increased intrinsic tension. The resonance running time measurement (RRTM) and the DD density were significantly reduced in overweight individuals. After a short-term but intense slimming process, the same individuals showed a trend to normalization of these two parameters without, however, reaching significance. Pooling all data yielded a significant logarithmic correlation between RRTM values and densities in Factor XIII a-positive DD. CONCLUSION: Factor XIII a expression in human DD may be partially regulated by the intrinsic resting tensions in the skin. [less ▲]

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