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See detailLes friches industrielles
Merenne-Schoumaker, Bernadette ULg; Bruyelle, P.; Kivell, P. T.

in Revue Belge de Géographie (1992), (50), 113-137

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See detailA fully coupled elastoplastic damage modeling and fracture criteria in metalforming processes
Zhu, Y. Y.; Cescotto, Serge ULg; Habraken, Anne ULg

in Journal of Materials Processing Technology (1992), 32

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See detailVoyages into Otherness: Cambridge and Lucy
Ledent, Bénédicte ULg

in Kunapipi : Journal of Postcolonial Writing (1992), 14(2), 53-63

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See detailLa réutilisation des friches
Merenne-Schoumaker, Bernadette ULg; Bruyelle, Pierre; Guillaume, Régis et al

in Revue Belge de Géographie (1992), (5), 179-208

Scientific dossier on the reuse of brownfield sites with case studies in France, Spain and Belgium and general reflections on the potential for reallocation

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See detailLa place de la vaccination en élevage bovin
Pastoret, Paul-Pierre ULg; Thiry, Etienne ULg; Baranowski, Eric

in Point Vétérinaire (1992), 24

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See detailExamens electrophysiologiques dans la migraine.
Schoenen, Jean ULg

in Pathologie Biologie (1992), 40(4), 293-304

This article is a critical review of standard electroencephalography (EEG), brain mapping, evoked potential, and electromyography (EMG) studies carried out in various forms of migraine during and between ... [more ▼]

This article is a critical review of standard electroencephalography (EEG), brain mapping, evoked potential, and electromyography (EMG) studies carried out in various forms of migraine during and between attacks. With the exception of contingent negative variation, the exteroceptive silent period of the temporalis muscle, and possibly fast activity in response to visual stimuli, which are useful for the differential diagnosis of functional headache, the main value of electrophysiologic studies is to provide insight into the pathophysiology of the disease. Results of the different methods consistently indicate that the brain of migraine patients is characterized by hypersensitivity to some forms of stimuli between attacks and by, often focal, hypoactivity during attacks. [less ▲]

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See detailExtended equal area criterion revisited
Xue, Yusheng; Wehenkel, Louis ULg; Belhomme, Régine et al

in IEEE Transactions on Power Systems (1992), PWRS-7(3), 1012-1022

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See detailStructure of the tilapia (Oreochromis mossambicus) prolactin I gene
Swennen, D.; Poncelet, A. C.; Sekkali, B. et al

in DNA & Cell Biology (1992), 11(9), 673-84

The tilapia (Oreochromis mossambicus) prolactin-I (PRL-I) gene has been cloned and sequenced. Its transcript (3,677 bases long) begins with a guanine and is organized in five exons and four introns like ... [more ▼]

The tilapia (Oreochromis mossambicus) prolactin-I (PRL-I) gene has been cloned and sequenced. Its transcript (3,677 bases long) begins with a guanine and is organized in five exons and four introns like the other known prolactin genes. Analysis of the 1,555-bp 5'-flanking region suggests that pituitary-specific expression of the gene could be regulated through a trans-factor related to the mammalian pituitary-specific factor Pit-1. Two potential binding sites for such a factor were found in the first intron, suggesting a possible regulatory role for this region. Moreover, two potential Z-DNA regions are located at positions -837 to -812 and -246 to -179 from the transcription start site. These two regions could play an important role in the regulation of PRL gene expression. [less ▲]

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See detailPHYLOGENETIC STUDY OF CYANOBACTERIA ON THE BASIS OF 16S RIBOSOMAL-RNA SEQUENCES
Nelissen, Bart; Wilmotte, Annick ULg; De Baere, Raymond et al

in Belgian Journal of Botany (1992), 125

In this study, the 16S rRNA sequences of five filamentous cyanobacteria (Cyanophyceae) have been determined. These sequences were used to construct, by a distance matrix method, a tree topology to depict ... [more ▼]

In this study, the 16S rRNA sequences of five filamentous cyanobacteria (Cyanophyceae) have been determined. These sequences were used to construct, by a distance matrix method, a tree topology to depict the phylogenetic relationships among cyanobacteria. [less ▲]

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See detailThe interaction between Bovine Leukemia Virus and its target cell.
Burny, Arsène; Kettmann, Richard ULg; Willems, Luc ULg et al

in AIDS Research and Human Retroviruses (1992), 8

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S ... [more ▼]

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S., Portetelle, D., Berte, C., Franssen, J. D., Herion, P., and Burny, A. (1982) Virology 122, 342-352; Voneche, V., Portetelle., D., Kettmann, R., Willems, L., Limbach, K., Paoletti, E., Ruysschaert, J. M., Burny, A., and Brasseur, R. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3810-3814) and suggest that a region encompassing residues 23 and 25 of gp51 is involved in this process (Portetelle, D., Couez, D., Bruck, C., Kettmann, R., Mammerickx, M., Van der Maaten, M., Brasseur, R., and Burny, A. (1989) Virology 169, 27-33; Mamoun, R., Morisson, M., Rebeyrotte, N., Busetta, B., Couez, D., Kettmann, R., Hospital, M., and Guillemain, B. (1990) J. Virol. 64, 4180-4188). X-ray diffraction studies performed on envelope glycoproteins of influenza virus indicate that the NH2-terminal part of the external glycoprotein lies very close to the fusion peptide. The same overall structure seems to exist in human immunodeficiency virus as suggested by site-directed mutagenesis followed by syncytia induction assays. Our theoretical studies indicate that a segment expanding between residues 19 and 27 of gp51 probably adopts an amphipathic beta-strand structure. We hypothesize that the amphipathic 19-27 structure of gp51 plays an important role in the process of membrane fusion by interacting with the fusion peptide or with another region of gp30. Mutational analysis disrupting the amphipathy of the 19-27 region strongly altered the fusogenic capacity of the gp51-gp30 complex. [less ▲]

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See detailInfluence of laminin or fibroblasts upon colony formation in the mouse by B16 melanoma cell spheroids: a morphometric analysis.
Coucke, P.; de Leval, Laurence ULg; Leyh, P. et al

in In Vivo (Athens, Greece) (1992), 6(2), 119-24

By microscopical observation and using an original morphometric method, we analyzed on histological sections the rate of lung colony formation after the intravenous injection into the mouse of B16 ... [more ▼]

By microscopical observation and using an original morphometric method, we analyzed on histological sections the rate of lung colony formation after the intravenous injection into the mouse of B16 melanoma cells previously cultivated in vitro as aggregates. After the injection of B16 pure spheroids, superficial lung colonies were more numerous than internal lung colonies. After the injection of mixed spheroids (B16 + 3T3 fibroblasts), the size of colony sections was increased. Addition of laminin to pure or mixed spheroids decreased the size of colony sections but increased the number of internal lung colonies. [less ▲]

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See detailThe Threshold Photoelectron Spectrum of NH3.
Locht, Robert ULg; Hottmann, K.; Hagenow, G. et al

in Chemical Physics Letters (1992), 190(1,2), 124-129

Using synchrotron radiation, we have investigated the threshold photoelectron spectrum of NH3 between 10-30 eV photon energy. In contrast to the He(I)-photoelectron spectrum, the threshold photoelectron ... [more ▼]

Using synchrotron radiation, we have investigated the threshold photoelectron spectrum of NH3 between 10-30 eV photon energy. In contrast to the He(I)-photoelectron spectrum, the threshold photoelectron spectrum shows three bands between 10 and 21 eV. The first band is dominated by the vibrational autoionization of the 5a1, the 6a1 and the 6pe Rydberg series. Between the first and second bands a new contribution, starting at 13.26 eV, is assigned to the autoionization of (a) member(s) of Rydberg series converging to the e-1 ionization continuum. Its (their) autoionization populates the upper vibrational levels of the NH3+ (X2A1) state. From about 14.5 eV the A2E band structures are identified. However, differences between the A2E band shapes in the He(I)- and the threshold photoelectron spectra suggest that very likely autoionization contributions are involved in the latter spectrum. These phenomena could play a role in the production of the NH2+ and NH+ fragment ions. The last very weak band, at about 25 eV in the photoelectron spectrum is assigned to the NH3+(B2A1) state. [less ▲]

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See detailHuman papillomavirus type 33 upstream regulatory elements can control gene expression in human cervical keratinocytes
Lauricella-Lefèbvre, M. A.; Rentier, Bernard ULg; Piette, Jacques ULg

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

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See detailArt et mise en scène
Duchesne, Jean-Patrick ULg

in Art&fact (1992), 11

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See detailLCAT activation properties of apo A-I CNBr fragments and conversion of discoidal complexes into spherical particles.
Vanloo, B.; Taveirne, J.; Baert, J. et al

in Biochimica et Biophysica Acta (1992), 1128(2-3), 258-66

We studied the substrate properties of the phospholipid-cholesterol-apolipoprotein complexes generated with apo A-I, apo A-I-CNBr fragments, apo A-II and apo A-IV for cholesterol esterification by the ... [more ▼]

We studied the substrate properties of the phospholipid-cholesterol-apolipoprotein complexes generated with apo A-I, apo A-I-CNBr fragments, apo A-II and apo A-IV for cholesterol esterification by the enzyme lecithin-cholesterol acyltransferase (LCAT). The kinetic parameters determined with the different complexes as substrates, showed that the complexes containing apo A-I and apo A-IV were about 40-times more efficient than those generated with the apo A-I fragments. In this system, the substrates containing apo A-II had the lowest efficiency. In spite of the differences in the kinetic parameters observed with the various apolipoprotein-lipid complexes, the cholesterol inserted in the complexes was esterified for more than 90% after 24 h in all systems studied. Based upon the results of the kinetic experiments, we followed the transformation of the discoidal complexes into spherical particles, due to the formation of a cholesteryl esters core, in the presence of low-density lipoproteins as an external source of cholesterol. We observed the formation of spherical particles by electron microscopy, after incubation of the discoidal complexes with LCAT for 24 h. The average percentage of cholesteryl esters in the converted particles was around 60% of the total cholesterol, varying between 40% for the apo A-I-CNBr-1-DPPC-cholesterol complex and up to 86% for the apo A-I-DPPC-cholesterol complex. The secondary structure of protein in the complexes was not significantly modified. However, the phospholipid phase transition disappeared, together with the parallel orientation of the phospholipid acyl chains with the helical segments of the apolipoproteins, as the phospholipids are organized in a monolayer at the surface of the spheres. [less ▲]

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See detailEditorial : la médecine comportementale : vingt ans après!
Fontaine, Ovide ULg; Etienne, Anne-Marie ULg

in Journal de Thérapie Comportementale et Cognitive (1992), 2(3), 2-3

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See detailVariation in Productive Efficiency in French Workers’ Cooperatives
Defourny, Jacques ULg; Lovell, C.A. Knox; N'gbo, Aké G.M.

in Journal of Productivity Analysis (1992), 3(1-2), 99-113

In this study, we explore the distribution of productive efficiency among workers’ cooperatives operating in each of four sectors of French manufacturing. We use stochastic frontier panel data techniques ... [more ▼]

In this study, we explore the distribution of productive efficiency among workers’ cooperatives operating in each of four sectors of French manufacturing. We use stochastic frontier panel data techniques to estimate production relationships in each sector, and to decompose output variation into input variation, variation in the effects of two indicators of the degree of worker participation in management, variation in productive efficiency, and an unexplained residual. In all four sectors we find that conventionally measured capital and labor inputs make a significant contribution to productivity. In only one sector do participation indicators contribute significantly. Variation in productive efficiency contributes significantly in all four sectors. [less ▲]

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See detailStatistical hydrodynamics in trickle flow columns
Crine, Michel ULg; Marchot, Pierre ULg; L'Homme, Guy ULg

in AIChE Journal (1992), 38

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See detailDetection of laminin receptor mRNA in human cancer cell lines and colorectal tissues by in situ hybridization.
Campo, E.; Monteagudo, C.; Castronovo, Vincenzo ULg et al

in American Journal of Pathology (1992), 141(5), 1073-83

The 67-kd high-affinity laminin receptor (67 LR) is a gene product whose expression appears to be associated with the invasive and metastatic phenotype of a variety of human cancer cells. Northern blot ... [more ▼]

The 67-kd high-affinity laminin receptor (67 LR) is a gene product whose expression appears to be associated with the invasive and metastatic phenotype of a variety of human cancer cells. Northern blot hybridization has been routinely used to quantify the level of 67 LR mRNA from total cellular RNA extracts of homogenized tissue specimens or in vitro grown cell populations. This technique is useful to assess the average expression of the 67 LR mRNA of a particular sample but does not provide information about expression in specific cell types nor about heterogeneity of expression from cell to cell. In this study, we analyzed the expression of 67 LR mRNA in four human cancer cell lines with varying degrees of expression of 67 LR protein (renal cancer A-704, breast carcinoma MCF-7/4 and MCF-7/7, and pancreatic cancer Panc-1) using in situ hybridization performed with 67 LR riboprobes. Total cellular RNA was simultaneously extracted from the cell lines and hybridized on Northern blots with a 67 LR cDNA probe to assess the validity of the mRNA detection by in situ hybridization. Sixty-seven LR mRNA expression was higher in Panc-1 and MCF-7/4 cells than in MCF-7/7 and renal carcinoma A-704. There was a direct correlation (R2 = 0.88) between the in situ hybridization analysis and the mRNA levels detected by Northern blot analysis. The in situ hybridization method showed a heterogeneous expression of the 67 LR mRNA in the four cell lines with different subpopulations of cells showing a range from negative to high levels of the message. Sixteen freshly frozen human colorectal tissues (seven adenocarcinomas, five matched normal mucosae, and four adenomas) were also analyzed by in situ hybridization. The 67 LR mRNA was localized in normal and neoplastic epithelial cells. Adenocarcinoma cells showed a 1.6- to 5-fold higher expression (P < 0.02 according to the Wilcoxon-Mann-Whitney test) than did epithelial colonic cells from normal mucosae or adenomas. The signal tended to be stronger in poorly differentiated carcinomas and carcinomas with metastases than in moderately differentiated and nonmetastatic tumors. We conclude that the high expression of 67 LR mRNA in colorectal tumors is due to an increased production by tumor cells. Furthermore, in situ hybridization is an effective method to detect the expression of LR mRNA in cultured cell lines as well as in frozen tissue sections. [less ▲]

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See detailEnvironmental monitoring at FUL
De Backer, Louis W.; Andre, Philippe ULg; Nicolas, Jacques ULg

in Journal on automatic control (1992), 33

The paper presents the research and teaching activities of Fondation Universitaire Luxembourgeoise (Arlon) and more particularly in the domain of Environmental Monitoring. Particular attention is given to ... [more ▼]

The paper presents the research and teaching activities of Fondation Universitaire Luxembourgeoise (Arlon) and more particularly in the domain of Environmental Monitoring. Particular attention is given to "intelligent measurement, bio-sensors and event forecast algorithms. The team of researchers tries to integrate the three steps of monitoring: measurement, data processing and decision making support. It develops short-term fog forecasting tools, water quality sensors, soil water status quality assessment techniques and uses models describing soil and water transfers in soils and artificial intelligence techniques applied to energy management in buildings. [less ▲]

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See detailEffect of endotoxin insult on critical closure in the canine pulmonary vasculature
D'Orio, Vincenzo ULg; FATEMI, M; MENDES, P et al

in Applied Cardiopulmonary Pathophysiology [=ACP] (1992), 4

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See detailOriginal lithotomy positioning for transperineal extracorporeal shockwave lithotripsy for distal ureteric calculi with Tripter X1.
Andrianne, Robert ULg; Vandeberg, Colette ULg; Bonnet, Pierre ULg et al

in European Urology (1992), 22(2), 134-6

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the ... [more ▼]

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the orientation of the semi-ellipsoid reflector) are adapted for the treatment of kidney or lumbar ureter stones. However, the elements forming the unit of treatment (the table, the C-arm and the Tripter) can be modified in such a way that focalization of stones of the lower ureter becomes possible through a perineal exposure. The aim is to avoid the pelvic bone shield while a good focalization of the stone is realized. From June 1989 to March 1991, 35 patients were treated for distal ureteric stones by ESWL in this original positioning. [less ▲]

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See detailThe Recognition of Hypothalamo-Neurohypophysial Functions by Developing T Cells
Robert, F. R.; Martens, Henri ULg; Cormann, N. et al

in Developmental Immunology (1992), 2(2), 131-40

Neuropeptide signals and specific neuropeptide receptors have been described in the thymus supporting the concept of a close dialogue between the neuroendocrine and the immune systems at the level of ... [more ▼]

Neuropeptide signals and specific neuropeptide receptors have been described in the thymus supporting the concept of a close dialogue between the neuroendocrine and the immune systems at the level of early T-cell differentiation. In this paper, we review recent data about neurohypophysial (NHP)-related peptides detected in the thymus from different species. We suggest that we are dealing in fact with other member(s) of the NHP hormone family, which seems to exert its activity locally through a novel model of cell-to-cell signaling, that of cryptocrine communication. This model involves exchange of signals between thymic epithelial cells and developing thymocytes. The NHP-related peptides have been shown to trigger thymocyte proliferation and could induce immune tolerance of this highly conserved neuroendocrine family. [less ▲]

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See detailLe bâtiment solaire passif de la Fondation Universitaire Luxembourgeoise à Arlon
Andre, Philippe ULg; Nicolas, Jacques ULg; Boreux, Jean-Jacques ULg et al

in Chaleur et climats (1992), (635), 2-8

Description des différentes technologies solaires passives: systèmes à gain direct, murs de masse et serres, mises en oeuvre lors de l'extension de la FUL. Présentation du bilan des performances de ca ... [more ▼]

Description des différentes technologies solaires passives: systèmes à gain direct, murs de masse et serres, mises en oeuvre lors de l'extension de la FUL. Présentation du bilan des performances de ca bâtiment basé sur deux années complètes de mesures intensives [less ▲]

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See detailVaginoplasty using amniotic membranes in cases of vaginal agenesis or after vaginectomy.
NISOLLE, Michelle ULg; Donnez, Jacques

in Journal of Gynecologic Surgery (1992), 8(1), 25-30

Various treatments have been proposed for vaginal agenesis. The authors describe successful procedures using amniotic membranes as a graft on vaginoplasties. The amnion was not stripped from the chorion ... [more ▼]

Various treatments have been proposed for vaginal agenesis. The authors describe successful procedures using amniotic membranes as a graft on vaginoplasties. The amnion was not stripped from the chorion. The results showed the vagina to be well formed and of normal depth and caliber. [less ▲]

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See detailMatériaux pour enseigner l'histoire des femmes
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1992), 42e année(n°3), 21-23

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See detailLe potentiel lent P300. Interet clinique dans trois pathologies mentales et neurobiologie: une revue.
Charles, G.; Hansenne, Michel ULg

in Encéphale (L') (1992), 18(3), 225-36

P300 is a late component of evoked potential which meet special relevance to the study of cognitive processes. P300 indexes categorization processes and the context updating of memory. Its latency ... [more ▼]

P300 is a late component of evoked potential which meet special relevance to the study of cognitive processes. P300 indexes categorization processes and the context updating of memory. Its latency reflects the stimulus evaluation time, and P300 amplitude is related to some psychological variables such as expectancy, attention and stimulus significance. In this review, clinical correlation between P300 components and mental diseases are reported, especially dementia, schizophrenia and depression. Delayed P300 latency has been found in Alzheimer disease and in other forms of dementia. Reduced P300 amplitude as well as altered topography has been reported in schizophrenia. In depression, reduced P300 amplitude has been related with longer reaction time. Unfortunately, the diagnosis utility of P300 seems limited. The authors also propose an overview of the actual knowledge on neurobiological findings in the generation of the P300 wave. Anatomical data point out the importance of the limbic system, more specifically, of the hippocampus and the locus coeruleus, in generating and modulating P300 wave. Data from the literature on the psychopharmacological modifications induced by cholinergic, catecholaminergic and other agents, are reviewed. Although the dopaminergic and noradrenergic systems are of some importance, these data emphasise the importance of the cholinergic system for the generation and modulation of P300 amplitude and latency. The value and interpretation of these neurobiological and clinical findings are discussed. [less ▲]

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See detailEchocardiographic Evaluation of Cardiac Morphologic and Functional Variables in Double-Muscled Calves
Amory, Hélène ULg; Kafidi, Nacereddine ULg; Lekeux, Pierre ULg

in American Journal of Veterinary Research (1992), 53(9), 1540-1547

We studied, by means of echocardiography in vivo, the cardiac consequences of the double-muscled character selection in beef cattle. Morphologic and functional echocardiographic variables were regularly ... [more ▼]

We studied, by means of echocardiography in vivo, the cardiac consequences of the double-muscled character selection in beef cattle. Morphologic and functional echocardiographic variables were regularly estimated in 17 Friesian and 8 Belgian White and Blue calves during their growth. A total of 50 and 44 sets of data were collected in each group, respectively. Recordings were obtained, using 2-dimensional and M-mode echocardiography, and included measurements in long- and short-axis views of the heart. Most of the diastolic measurements of the left ventricle were not significantly different between breeds when normalized for body weight. To the contrary, systolic measurements of left ventricular wall thickness and dimensions were significantly (P less than or equal to 0.001) lower and greater, respectively, in Belgian White and Blue calves than in Friesian calves. This was interpreted as a result of significantly (P less than or equal to 0.001) lower left ventricular systolic functional indices in Belgian White and Blue than in Friesian calves. Echocardiographic evidence that the double-muscled selection in cattle induces alteration in morphologic variables of left ventricle was not found. However, results indicate that indices of left ventricular systolic function are lower in double-muscled calves than in calves with standard conformation. [less ▲]

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See detailPour une dramaturgie du Miracle d'Amis et Amille
Henrard, Nadine ULg

in Moyen français (1992), 30

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See detail2- and 4-[18F]fluorotropapride, two specific D2 receptor ligands for positron emission tomography: N.C.A. syntheses and animal studies.
Damhaut, Philippe; Cantineau, Robert; Lemaire, Christian ULg et al

in International Journal of Radiation Applications and Instrumentation. Part A : Applied Radiation and Isotopes (1992), 43(10), 1265-74

Tropapride, (exo)-2,3-dimethoxy-N-[8-(phenylmethyl)-8- azabicyclo[3.2.1]oct-3-yl]benzamide hydrochloride, has been labeled with fluorine-18 at the 2- and 4-positions of its benzylic group. Two synthetic ... [more ▼]

Tropapride, (exo)-2,3-dimethoxy-N-[8-(phenylmethyl)-8- azabicyclo[3.2.1]oct-3-yl]benzamide hydrochloride, has been labeled with fluorine-18 at the 2- and 4-positions of its benzylic group. Two synthetic pathways were investigated: the first one required the alkylation of the norbenzyl precursor with 2- or 4-[18F]fluorobenzyl bromide (radiochemical yield of 5% EOB, 180 min); the second method consisted of a reductive amination of norbenzyl tropapride with 2- or 4-[18F]fluorobenzaldehyde (20% EOB, 110 min). In both cases, the specific activity was found to be greater than 1 Ci/mumol (EOS). Animal studies in rats showed the percentage of the injected dose localizing in the whole brain to be 0.6 +/- 0.09 and 0.2 +/- 0.03 at 2 h post injection for the para- and the ortho-[18F]fluoro analogs of tropapride respectively. Cerebral biodistribution studies showed at 4 h a striatum uptake of 5 +/- 0.7% of the injected dose per gram of striatum for the para derivative with a low fixation into the frontal cortex and the cerebellum (% ID/g FC < 0.4 and % ID/g Cb < 0.3). The selectivity of 4-[18F]fluorotropapride for D2 dopaminergic sites was demonstrated through blocking experiments with ketanserin, spiperone and halopemide. The saturability was confirmed by the use of variable specific activities. These preliminary results showed that 4-[18F]fluorotropapride can be considered as a potent radiopharmaceutical for the study of the dopaminergic system with PET. [less ▲]

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See detailDesign, Synthesis and Biological Activity of a Series of Torasemide Derivatives, Potent Blockers of the Na+ 2cl- K+ Co-Transporter: In-Vitro Study
Masereel, B.; Lohrmann, E.; Schynts, M. et al

in Journal of Pharmacy & Pharmacology (1992), 44

Pharmacomodulation of the torasemide molecule, a loop diuretic inhibiting Na+ 2Cl- K+ co-transport in the thick ascending limb of the loop of Henle has been performed in order to obtain new long-acting ... [more ▼]

Pharmacomodulation of the torasemide molecule, a loop diuretic inhibiting Na+ 2Cl- K+ co-transport in the thick ascending limb of the loop of Henle has been performed in order to obtain new long-acting diuretics. The aim of this study was to decrease the metabolism of the drug and to slow down its rate of excretion by increasing its hydrophobicity. The present study describes the synthesis and the inhibitory potency of new torasemide derivatives in the bioassay system of the cortical thick ascending limb of rabbit. A correlation between the lipophilicity (log P') of these substances and their activity as inhibitors of the Na+ Cl- K+ co-transporter was observed. The present design led to compounds more active than torasemide. Structure-activity relationships permit us to propose an interaction model between torasemide derivatives and the Na+ 2Cl- K+ co-transport system of the cortical thick ascending limb. [less ▲]

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See detailInfluence of the Counterpoise Correction on the Optimized Relativi Degrees of Freedom in the H-Bonded Complex Water-Formamide
Dehareng, Dominique ULg; Dive, Georges ULg; Ghuysen, Jean-Marie ULg

in Theoretica Chimica Acta (1992), 81(4-5), 281-290

The correction of the basis set superposition error by the counterpoise method has been investigated at the SCF level for the weak H-bonded water-formamide complex and the results have been compared with ... [more ▼]

The correction of the basis set superposition error by the counterpoise method has been investigated at the SCF level for the weak H-bonded water-formamide complex and the results have been compared with the uncorrected results at the SCF, post SCF and semi-empirical AM1 and MNDO levels. Our particular concern has been the determination of the three optimized relative degrees of freedom and the relative stability of three C(s) geometrical conformations. The conclusions are that the counterpoise correction weakly conditions the variation in the degrees of freedom and the relative stabilities of the three conformers. The correction is obviously inadequate to describe intramolecular deformation. [less ▲]

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See detailMort, mentalité et tradition à la lumière des ballades de Terre-Neuve
Peere, Isabelle ULg

in Canadian Folklore Canadien (1992), 14(2), 137-58

A talerole analysis of prominent Newfoundland ballad and narrative song records on the theme of death highlighting coherent meaning throughout the different layers of the local song tradition, i.e. an ... [more ▼]

A talerole analysis of prominent Newfoundland ballad and narrative song records on the theme of death highlighting coherent meaning throughout the different layers of the local song tradition, i.e. an exclusive and constant preoccupation with tragic, sudden, premature and violent death as an inspiration to courage and responsibility rather than despair or resignation. [less ▲]

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See detailMolecular properties of cinchona alkaloids: a theoretical approach
Oleksyn, Barbara; Suszko-Purzycka, Alina; Dive, Georges ULg et al

in Journal of Pharmaceutical Sciences (1992), 81(2), 122-127

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See detailNudus... infans... A propos de Lucrèce, V, 222-227
Rochette, Bruno ULg

in Etudes Classiques (Namur, Belgium) (1992), 60

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See detailOntogeny of T-Cell Surface Molecules and Receptors in the Thymus
Defresne, Marie-Paule ULg; Humblet, Chantal ULg; Deman, J. et al

in Progress in Histochemistry and Cytochemistry (1992), 26(1-4), 194-200

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See detailModification of the Selected Method for the Determination of Serum Iron. Substitution of Bathophenanthroline by Ferene S
Charlier, Corinne ULg; Plomteux, Guy ULg; Vernet, M. et al

in Annales de Biologie Clinique (1992), 50(3), 191-202

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene ... [more ▼]

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene S is used as the chromogen, it is more sensitive and cheaper than bathophenanthroline. The sample size has been reduced from 2 to 0.5 ml. No interference could be shown with high concentrations of bilirubin, copper or hemoglobin. [less ▲]

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See detailAvant-propos. Rapport préliminaire sur les 1re et 2e campagnes de fouille à Tell Amarna (Syrie)
Tunca, Önhan ULg

in Chronique archéologique en Syrie 1 (1992)

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See detailAcyclovir vs isoprinosine (immunovir) for suppression of recurrent genital herpes simplex infection.
Kinghorn, G. R.; Woolley, P. D.; Thin, R. N. et al

in Genitourinary Medicine (1992), 68(5), 312-6

OBJECTIVE: To compare the efficacy and safety of oral acyclovir (400 mg twice daily) with oral isoprinosine (500 mg twice daily) in the suppression of recurrent genital herpes. DESIGN: Double-blind ... [more ▼]

OBJECTIVE: To compare the efficacy and safety of oral acyclovir (400 mg twice daily) with oral isoprinosine (500 mg twice daily) in the suppression of recurrent genital herpes. DESIGN: Double-blind, double-dummy, randomised, controlled, parallel group trial. SETTING: 13 centres in UK, Belgium and Germany. SUBJECTS: 127 immunocompetent patients with frequently recurring genital herpes. MAIN OUTCOME MEASURES: Proportions of patients reporting recurrences, recurrence frequency, and mean duration of lesions during breakthrough recurrences in each treatment group during a 6 month treatment period; time to first recurrence during treatment and follow-up after treatment cessation. RESULTS: During treatment, acyclovir recipients showed significant differences (p < 0.05) when compared with isoprinosine recipients in terms of a lower proportion reporting recurrences (31% vs 96%), a reduced mean number of reported recurrences per patient (0.6 vs 3.6), a shorter mean duration of breakthrough lesions (6.4 days vs 8.2 days), and a longer mean time (standard error) to first recurrence (143.7 (9.1) days vs 40.5 (5.4) days. The mean time to first recurrence after treatment cessation did not differ between the two groups. As compared with placebo recipients, isoprinosine treated patients had an increased recurrence frequency (3.6 vs 2.5) during treatment, and a shorter time to first recurrence after treatment cessation. All treatments were well tolerated without serious adverse events or toxicity. CONCLUSIONS: Acyclovir is very effective in suppressing recurrent genital herpes and is clearly superior to isoprinosine which is not clinically useful in the dosage studied. [less ▲]

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See detailSubstituabilité partielle des facteurs et efficacité-coût. L'exemple du transport urbain et vicinal belge.
Delhausse, Bernard; Thiry, Bernard; Perelman, Sergio ULg

in Economie et Prévision (1992)

Le but de l’article est de mesurer les niveaux d’efficacité d’entreprises de transport, urbain et interurbain, de passagers. Le modèle théorique permet de combiner des facteurs simultanément ... [more ▼]

Le but de l’article est de mesurer les niveaux d’efficacité d’entreprises de transport, urbain et interurbain, de passagers. Le modèle théorique permet de combiner des facteurs simultanément complémentaires et substituables. L’importance des liens de complémentarité entre certains facteurs de production apparaît. Les calculs des niveaux d’efficacité font ressortir l’amélioration des firmes concernées au fil du temps. [less ▲]

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See detailTHE TRIPLET-STATES OF ALBR
BREDOHL, Harald; DANGUY, P.; DUBOIS, Iwan et al

in Journal of Molecular Spectroscopy (1992), 151(1), 178-183

Twenty bands of the a3Πr-X1Σ+ transition of AlBr have been rotationally analyzed involving v′ from 0 to 10 and v″ from 0 to 8. The Π1 component is perturbed in the v = 0 and 1 vibrational levels. A new ... [more ▼]

Twenty bands of the a3Πr-X1Σ+ transition of AlBr have been rotationally analyzed involving v′ from 0 to 10 and v″ from 0 to 8. The Π1 component is perturbed in the v = 0 and 1 vibrational levels. A new system has been observed for the first time; it is formed of 26 bands and is interpreted as the b3Σ+-X1Σ+ transition. [less ▲]

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See detailPulmonary arterial impedance and right ventricular function in a canine model of septic shock
D'Orio, Vincenzo ULg; MARTINEZ, Christophe ULg; SAAD, G et al

in Intensive Care Medicine (1992), 18-S2

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See detailMODELING THE PHANEROZOIC CARBON-CYCLE AND CLIMATE - CONSTRAINTS FROM THE SR-87-SR-86 ISOTOPIC RATIO OF SEAWATER
François, Louis ULg; WALKER, J. C. G.

in American Journal of Science (1992), 292(2), 81-135

A numerical model describing the coupled evolution of the biogeochemical cycles of carbon, sulfur, calcium, magnesium, phosphorus, and strontium has been developed to describe the long-term changes of ... [more ▼]

A numerical model describing the coupled evolution of the biogeochemical cycles of carbon, sulfur, calcium, magnesium, phosphorus, and strontium has been developed to describe the long-term changes of atmospheric carbon dioxide and climate during the Phanerozoic. The emphasis is on the effects of coupling the cycles of carbon and strontium. Various interpretations of the observed Phanerozoic history of the seawater Sr-87/Sr-86 ratio are investigated with the model. More specifically, the abilities of continental weathering, volcanism, and surface lithology in generating that signal are tested and compared. It is suggested that the observed fluctuations are mostly due to a changing weatherability over time. It is shown that such a conclusion is very important for the modelling of the carbon cycle. Indeed, it implies that the conventional belief that the evolution of atmospheric carbon dioxide and climate on a long time scale is governed by the balance between the volcanic input of CO2 and the rate of silicate weathering is not true. Rather carbon exchanges between the mantle and the exogenic system are likely to have played a kev role too. Further, the increase of the global weathering rates with increasing surface temperature and/or atmospheric CO2 pressure usually postulated in long-term carbon cycle and climate modelling is also inconsistent with the new model. Other factors appear to have modulated the weatherability of the continents through time, such as mountain building and the existence of glaciers and ice sheets. Based on these observations, a history of atmospheric carbon dioxide and climate during Phanerozoic time, consistent with the strontium isotopic data, is reconstructed with the model and is shown to be compatible with paleoclimatic indicators, such as the timing of glaciation and the estimates of Cretaceous paleotemperatures. [less ▲]

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See detailMéthode actuelle de contrôle de la cochenille pulvinaire (Eupulvinaria hydrangeae Steinweden) en Belgique
Tondeur, R.; Verstraeten, Ch.; Schiffers, Bruno ULg

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), 35

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See detailLa carrière de marbre rouge de Beauchâteau: aperçu paléontologique, stratigraphique et sédimentologique
Boulvain, Frédéric ULg; Coen-Aubert, M.

in Annales de la Société Géologique de Belgique (1992), 115

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See detailA sensitivity study of the role of continental area and location on Paleozoic climate
Hauglustaine, Didier A.; Gérard, Jean-Claude ULg

in Global and Planetary Change (1992), 97

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See detailLes bactéries lactiques, une aide alimentaire.
Thonart, Philippe ULg; Roblain, D.

in Mellitus Magazine (1992), 3

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See detailIdentification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin.
Castronovo, Vincenzo ULg; Luyten, F.; van den Brule, F. et al

in Archives of Biochemistry & Biophysics (1992), 297(1), 132-8

The carbohydrate moieties present on laminin play a crucial role in the multiple biological activities of this basement membrane glycoprotein. We report the identification of a human laminin binding ... [more ▼]

The carbohydrate moieties present on laminin play a crucial role in the multiple biological activities of this basement membrane glycoprotein. We report the identification of a human laminin binding protein with an apparent molecular mass of 14 kDa on sodium dodecyl sulfate-polyacrylamide gels that was found, after purification and amino acid microsequencing, to be identical to the previously described 14-kDa galactoside binding soluble L-14 lectin. We have designated this human laminin binding protein as HLBP14. HLBP14 was purified from human melanoma cells in culture by laminin affinity chromatography and gel electroelution. We demonstrate that HLBP14 binds specifically to the poly-N-acetyllactosamine residues of murine laminin and does not bind to other glycoproteins that do not contain such structures, such as fibronectin. HLBP14 was eluted from a murine laminin column by lactose, N-acetyllactosamine, and galactose but not by other control saccharides, including glucose, fucose, mannose, and melibiose. It did not bind to laminin treated with endo-beta-galactosidase. Lactose also eluted HLBP14 off a human laminin affinity column, implying that human laminin also contains poly-N-acetyllactosamine residues. On immunoblots, polyclonal antibodies raised against HLBP14 recognized HLBP14 as well as 31- and 67-kDa molecules that are also laminin binding proteins, indicating that these proteins share common epitopes. L-14, a dimeric lactose binding lectin, is expressed in a wide variety of tissues. Although the expression of this molecule has been linked to a variety of biological events, the elucidation of its specific functions has been elusive. The observation that HLBP14, a human cancer cell laminin binding protein, is identical to L-14 strongly suggests that the functions attributed to this lectin could be mediated, at least in part, through its ability to interact with the poly-N-acetyllactosamine residues of laminin. HLBP14 could potentially play a role during tumor invasion and metastasis by modulating the interactions between cancer cells and laminin. [less ▲]

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See detailAlteration of fetal development and hormonal status after dam treatment with anti-insulin like growth factor-I monoclonal antibodies in rat.
Renaville, Robert ULg; Devolder, Anne; Sneyers, Myriam et al

in Journal of Endocrinological Investigation (1992), 15(suppl 4), 85

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See detailAntagonistes calciques et calcithérapie : incompatibilité ?
Mottard, L; Lecart, MP; Reginster, Jean-Yves ULg

in Actualité Médicale Belge (1992), 335

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See detailEchelles d'auto-évaluation de la dépression et de l'anxiété
Crasson, Marion ULg

in Psychologie Médicale (1992), 24(11), 1216-1220

Différents types d'échelle d'évaluation se sont développées depuis l'avènement des psychotropes dans les années 50. La passation de certaines d'entre elles, particulièrement les échelles d'auto-évaluation ... [more ▼]

Différents types d'échelle d'évaluation se sont développées depuis l'avènement des psychotropes dans les années 50. La passation de certaines d'entre elles, particulièrement les échelles d'auto-évaluation, peut se réaliser facilement via des systèmes informatisés. Nous présenterons deux de ces échelles, pour lesquelles nous disposons de données normatives et qui sont fréquemment utilisées dans notre laboratoire: l'échelle de dépression de Plutchik et van Praag (PVP) et l'échelle d'anxiété Etat-Trait de Spielberger et coll. (STAI). [less ▲]

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See detailMicroflore des monticules frasniens "F2j" de Belgique
Mamet, B.; Boulvain, Frédéric ULg

in Revue de micropaléontologie (1992), 35(4), 283-302

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See detailLes facteurs sous-jacents à l'étude et susceptibles d'influencer les options du schéma de structure communal
Collette, Jean-Pierre ULg; Goossens, Marc ULg; Hanocq, Philippe ULg

in Environnement et Société (1992), 9/10

Analyse de certains facteurs "externes" au projet d'aménagement mais exerçant une influence déterminante sur ses orientations : la confrontation des objectifs communaux et régionaux, les contraintes ... [more ▼]

Analyse de certains facteurs "externes" au projet d'aménagement mais exerçant une influence déterminante sur ses orientations : la confrontation des objectifs communaux et régionaux, les contraintes techniques et politiques locales, les groupes de pression divers. [less ▲]

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See detailPalynostratigraphy of the Tournaisian (Hastarian) rocks in the Namur Synclinorium, West Flanders, Belgium.
Higgs, K; Dreesen, R; Dusar, M et al

in Review of Palaeobotany and Palynology (1992), 72

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See detailLa répartition des noms propres dans les œuvres érotiques d’Ovide
Purnelle, Gérald ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1992)

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See detailLe sexage d'embryons bovins par la technique de l'amplification en chaîne par la polymérase (acp) d'une séquence Y-spécifique bovine
Grobet, Luc ULg; Schwers, Anne; Charlier, Carole ULg et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailExpression of members of the putative olfactory receptor gene family in mammalian germ cells.
Parmentier, M.; Libert, F.; Schurmans, Stéphane ULg et al

in Nature (1992), 355

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the ... [more ▼]

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the unidentified receptors ('orphan receptors'), a human genomic clone (HGMP07) was characterized by the presence of its transcripts in the testis and by its belonging to a large subfamily of genes sharing extensive sequence similarities. Sequence comparison demonstrated that this gene subfamily is the human counterpart of the putative rat olfactory receptors cloned recently. Another 48 members of the family were cloned. Northern blotting further demonstrated the presence of olfactory receptor transcripts in germ cells. Our finding suggests that a common receptor gene family encodes olfactory receptors and sperm cell receptors that could be involved in chemotaxis during fertilization [less ▲]

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See detailLa politique québécoise d'alphabétisation
Martiniello, Marco ULg

in Hommes & Migrations (1992), 1151-1152

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See detailImportance et dynamique du complexe parasitaire du cotonnier dans la région de Gandajika au Zaïre
Delhove, G.; Mergeai, Guy ULg; Mulamba, K.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), (35), 379-387

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See detailA quasi-Newton algorithm for first-odrer saddle-point location
Culot, Patrick; Dive, Georges ULg; Nguyen, Van Hen et al

in Theoretica Chimica Acta (1992), 82

A new algorithm for the location of a transition-state structure on an energy hypersurface is proposed. The method is compared to three other quasi-Newton step calculations available in literature ... [more ▼]

A new algorithm for the location of a transition-state structure on an energy hypersurface is proposed. The method is compared to three other quasi-Newton step calculations available in literature. Numerical results derived from several examples are compared to those obtained by the two algorithms implemented in the Gaussian package. [less ▲]

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See detailTranscriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factor
Voz, Marianne ULg; Peers, Bernard ULg; Wiedig, Murielle J et al

in Molecular & Cellular Biology (1992), 12(9), 3991-7

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding ... [more ▼]

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding element (TBE) spanning coordinates -67 to -41. This TBE is adjacent to the binding site for pituitary factor GHF1 (-95 to -68) which seems necessary for T3 stimulation of hCS-B promoter activity (M. L. Voz, B. Peers, A. Belayew, and J. A. Martial, J. Biol. Chem. 266:13397-13404, 1991). We here demonstrate actual synergy between the thyroid receptor and GHF1. Indeed, in placental JEG-3 cells devoid of factor GHF1, hCS promoter activity is barely stimulated by T3, while a strong response is observed in pituitary GC cells. In the latter, furthermore, neither the TBE nor the GHF1-binding site alone is sufficient to render the thymidine kinase promoter responsive to T3, while in combination they promote strong T3 stimulation. Close proximity between these sites is required for optimal synergy: T3 stimulation globally decreases with increased spacing. Furthermore, synergy occurs not only with a GHF1-binding site but also with all other factor recognition sequences tested (Sp1, NF1, CP1, Oct1, and CACCC boxes) and even with two other copies of the TBE. Nor is it specific to hCS TBE, since the palindromic sequence TCAGGTCA TGACCTGA (TREpal) also exhibits cooperativity. [less ▲]

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See detailPlant greening - Biogenesis of photosynthetic apparatus in bean leaves irradiated shortly after germination
Schoefs, B.; Bertrand, M.; Franck, Fabrice ULg

in Photosynthetica (1992), 27(4), 497-504

Formation of the photosynthetic apparatus in dark-grown 2-day-old bean (Phaseolus vulgaris L.) leaves was studied. The photosystem 2 (PS 2) reaction centres started functioning 1 h after the beginning of ... [more ▼]

Formation of the photosynthetic apparatus in dark-grown 2-day-old bean (Phaseolus vulgaris L.) leaves was studied. The photosystem 2 (PS 2) reaction centres started functioning 1 h after the beginning of irradiation. Electron transport between the two photosystems started after 4 h of irradiation. The PS 2 units were able to transfer the excitation energy to each other after 10 h of greening. The photosynthetic activity appeared a long time before the typical 77 K fluorescence bands of green leaves appeared. [less ▲]

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See detailDensitometric Evaluation of Spiraeoside after Derivatization in Flowers of Filipendula Ulmaria (L.) Maxim
Poukens-Renwart, P.; Tits, Monique ULg; Wauters, Jean-Noël ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (1992), 10(10-12, Oct-Dec), 1085-8

Spiraeoside (quercetin-4'-glucoside) is the major and most caharacteristic flavonoid of Filipendula ulmaria flowers and is not found in the leaves and stems. This paper describes a quantification of ... [more ▼]

Spiraeoside (quercetin-4'-glucoside) is the major and most caharacteristic flavonoid of Filipendula ulmaria flowers and is not found in the leaves and stems. This paper describes a quantification of spiraeoside by HPTLC densitometry after derivatization with diphenylboric acid -2-aminoester. The fluorescence of this flavonoid was measured at 330 nm. the spiraeoside content in batches of Filipendula ulmaria flowers ranged from 3 to 4.3 %. It is of note that these results are similar to those published elsewhere after HPLC analysis of other batches. [less ▲]

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See detailGrowth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats.
Reiter, E.; Bonnet, Pierre ULg; Sente, B. et al

in Molecular & Cellular Endocrinology (1992), 88(1-3), 77-87

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented ... [more ▼]

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented with highly purified human prolactin (hPRL), human luteinizing hormone (hLH), porcine follicle-stimulating hormone (pFSH), and bovine growth hormone (bGH) or with saline. Quantitative analysis of RNAs shows that treatment with either PRL or GH increases significantly steady-state mRNAs levels of the following genes in the prostate: androgen receptor (AR) (respectively 3.5- and 4.8-fold above hypox controls), IGF-I (5- and 2.7-fold), and IGF-I receptor (2.9- and 2.3-fold). LH and FSH, by contrast, have negative effects on these parameters. To test whether the enhancing effect of PRL and GH on AR-mRNA abundance was followed by increased content in the protein itself, binding assays were performed with the androgen agonist [3H]R1881 (131 and 153 fmol/mg protein while hypox controls contained 110 fmol/mg protein). In addition to the well-documented presence of prolactin receptors in prostatic tissues, we have further demonstrated, by means of nuclease S1 protection assays plus dot- and Northern-blot analyses, that a GH receptor mRNA is produced in the immature rat prostate. Moreover, we observed not only strong lactogenic but also purely somatogenic binding to be occurring in the immature prostates. Finally, we have studied IGF-I mRNA content in separated epithelial/stromal cell fractions and have concluded that IGF-I expression is principally located in the prostatic stroma. Taken together, these results suggest that PRL and GH are involved in regulating AR synthesis, at least partially by direct action on the organ. In this context IGF-I appears as a paracrine factor playing a role in epithelium/stroma interactions during prostatic development. [less ▲]

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See detailDawsonites magnus sp. nov., une plante nouvelle du Dévonien inférieur d'Ensival (Belgique).
Gerrienne, Philippe ULg

in Comptes Rendus de l'Académie des Sciences. Série II. Mécanique, Physique, Chimie, Sciences de l'Univers, Sciences de la Terre (1992), 315

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See detailHuman placental growth hormone
Frankenne, Francis; Evain-Brion, Danielle; Alsat, Eliane et al

in Anales Espanoles de Pediatria (1992), 36(50), 77-80

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See detailCalcitonin and bone diseases
Reginster, Jean-Yves ULg

in Lancet (1992), 339

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See detailCompte-rendu de l'ouvrage de Serge Paugam: La disqualification sociale
Robert, Jocelyne ULg

in Revue de l'Institut de Sociologie (1992)

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See detailLe site et la fouille
Tunca, Önhan ULg

in Akkadica (1992), 79-80

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See detailHémorragies cérébro-méningées par rupture d'anévrysme artériel intracrânien
Pirotte, B.; Born, JD.; HANS, Pol ULg et al

in Revue Médicale de Liège (1992), 18

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See detailSkinner, mentalismo y cognitivismo
Richelle, Marc ULg

in Anuario de Psicologia (1992), 52(1), 3-15

This paper discusses Skinner's antimentalim related to his radical behaviourism - oppposed to methological behaviourism - and secondly related to the recent evolution towards the cognitivist approach. We ... [more ▼]

This paper discusses Skinner's antimentalim related to his radical behaviourism - oppposed to methological behaviourism - and secondly related to the recent evolution towards the cognitivist approach. We can distinguish different versions in such approach which differ in their methodological, epistemological, ethical and practical contents. References to Skinner's latest writings illustrate his position to these ways of cognitivism. [less ▲]

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See detailEtude de l'efficacité de matières actives insecticides à l'égard des principaux parasites du cotonnier au sud du Zaïre
Delhove, G.; Mergeai, Guy ULg; Mulamba, K.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), (35), 389-395

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See detailFaut-il encore mesurer la performance des entreprises publiques?
Gathon, Henry-Jean ULg; Pestieau, Pierre ULg

in Annals of Public and Cooperative Economics = Annales de l'Economie Publique, Sociale et Coopérative (1992), 63(4), 621-644

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See detailMiospores et Foraminifères du Famennien des Massifs des Mdakra et du Khatouat (Maroc).
Vachard, D; Loboziak, S; Fadli, D et al

in Sciences Géologiques : Mémoire (1992), 83

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See detailEmperipolesis of lymphoid cells by human follicular dendritic cells in vitro.
Tsunoda, R.; Nakayama, M.; Heinen, Ernst ULg et al

in Virchows Archiv. B : Cell pathology (1992), 62(2), 69-78

Isolated follicular dendritic cells (FDCs) showed true and pseudoemperipolesis of fresh tonsillar lymphocytes, even after long-term (50-day) cultivation. Emperipolesis by FDCs was not restricted by ... [more ▼]

Isolated follicular dendritic cells (FDCs) showed true and pseudoemperipolesis of fresh tonsillar lymphocytes, even after long-term (50-day) cultivation. Emperipolesis by FDCs was not restricted by allotype specificity, nor was it inhibited by the addition of antibodies against MHC-I & II antigens. Follicular dendritic cells predominantly engulfed B-cells; monocytes and macrophages were not found between FDC cytoplasmic extensions. When highly purified T-cell populations were added to FDC cultures emperipolesis of T-cells occurred, particularly those of the CD4-positive phenotype. Mitoses appeared within 6 h in the emperipolesed lymphocytes and, after an additional 18 h, some lymphocytes exhibited apoptosis. [less ▲]

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See detailIdentification of patients at high risk for recurrence of sustained ventricular tachycardia after healing of acute myocardial infarction.
Rodriguez, L M; Oyarzun, R; Smeets, J et al

in American Journal of Cardiology (1992), 69(5), 462-4

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular ... [more ▼]

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular fibrillation (VF) after healing of acute myocardial infarction. 74 patients (36%) (64 with VT and 10 with VF) had recurrences of sustained monomorphic VT during 3.4 +/- 9 years of follow-up. Three clinical variables were selected and weighted by stepwise logistic discriminant analysis of the study group. They were coded as follows: interval of myocardial infarction to arrhythmia (less than 2 months = 1; 2 to 6 months = 2; greater than 6 months = 3), drug therapy with or without sotalol (with = 1, without = 2), and VT or VF as the presenting arrhythmia (VT = 1, VF = 2). The prognostic index was: 3.41 - (0.56 x interval) - (1.94 x therapy) + (0.86 x arrhythmia). This index was validated prospectively in a test group of 158 consecutive patients with VT or VF after healing of acute myocardial infarction. Patients were allocated into different classes with decreasing prognostic index values associated with increasing risk for recurrences of VT. In the test group, 27 of 158 (17%) patients (22 with VT and 5 with VF) had recurrences of VT (follow-up of 2 +/- 2 years). Two risk classes of patients were identified: high risk for recurrences of VT (61%) corresponding to patients with a negative index; and low risk (4%) consisting of those with a positive index. Thus, using O as the cutoff point, the sensitivity, specificity, and positive and negative predictive values were 81, 89, 62 and 96%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailCharacterization of regulatory functions of the varicella-zoster virus gene-63-encoded protein
Jackers, Pascale ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Journal of Virology (1992), 66(6), 3899-3903

Varicella-zoster virus (VZV) gene 63 encodes a protein (IE63) with a predicted molecular mass of 30.5 kDa which has amino acid similarities to the immediate-early (IE) protein 22 (ICP22) of herpes simplex ... [more ▼]

Varicella-zoster virus (VZV) gene 63 encodes a protein (IE63) with a predicted molecular mass of 30.5 kDa which has amino acid similarities to the immediate-early (IE) protein 22 (ICP22) of herpes simplex virus type 1. ICP22 is a polypeptide synthesized in herpes simplex virus type 1-infected cells, and as is the case for its VZV counterpart, its regulatory functions are unknown. On the basis of the VZV DNA sequence, it has been shown that IE63 exhibits hydrophilic and acidic properties, suggesting that this protein could play a regulatory role during the infectious cycle. We report in this article cotransfection experiments which demonstrate that the VZV gene 63 protein strongly represses, in a dose-dependent manner, the expression of VZV gene 62. On the other hand, transient expression of the VZV gene 63 protein can promote activation of the thymidine kinase gene but cannot affect the expression of the genes encoding glycoproteins I and II. The results of transient expression experiments strongly suggest that the VZV gene 63 protein could play a pivotal role in the repression of IE gene expression as well as in the activation of early gene expression [less ▲]

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See detailLéonard Defrance, l'Émulation de Liège et l'Esprit des journaux
Droixhe, Daniel ULg

in Revue Belge d'Archéologie et d'Histoire de l'Art (1992), 61

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See detailTwo-dimensional study of varicella-zoster virus proteins
Debrus, S.; Lebon, L.; Schoonbroodt, Sonia et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100(2), 39

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See detailBrachiocephalic Arterial Reconstruction
VAN DAMME, Hendrik ULg; Caudron, D.; Defraigne, Jean-Olivier ULg et al

in Acta Chirurgica Belgica (1992), 92(1), 37-45

From 1980 to 1990, 18 patients underwent trans-sternal repair for occlusive disease of the brachiocephalic artery. The mean age was 57 years (43-72). Most of the patients were women (n = 10). All but two ... [more ▼]

From 1980 to 1990, 18 patients underwent trans-sternal repair for occlusive disease of the brachiocephalic artery. The mean age was 57 years (43-72). Most of the patients were women (n = 10). All but two patients had one or more symptoms related to the stenosis of the brachiocephalic trunk: right-sided upper limb ischemia (n = 7), transient ischemic attacks (n = 8), vertebrobasilar insufficiency (n = 6), left sided minor stroke (n = 1). Only two patients were asymptomatic before operation. Angiography revealed a tight stenosis (n = 14) or an occlusion (n = 3); in one patient it concerned an ulcerated non-stenotic plaque of the brachiocephalic artery. Eleven patients had coexistent involvement of other supraaortic vessels. Angiographically, clinically and intraoperatively, there was evidence of Takayasu arteritis in three female patients. All patients had direct repair by trans-sternal approach. Six patients with short lesions had thromboendarterectomy with patch angioplasty of the innominate artery. In eleven cases, aorto-brachiocephalic bypass grafting was performed. In one patient, aortic calcification precluded proximal anastomosis, and a carotid-to-carotid bypass was done. In five patients, simultaneous revascularization of subclavian (n = 3), left common carotid (n = 2) or internal carotid artery (n = 2) completed the procedure. In one patient, concomitant coronary revascularization was done. There was no operative mortality. Postoperative morbidity was limited to pulmonary infection (n = 2), transient neurologic deficit (n = 1) and renal insufficiency (n = 1). All patients had relief of symptoms. Duplex echo scan confirmed patency of all reconstructions at a mean follow-up of 46 months.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailHIV-1 reactivation after an oxidative stress
Legrand, Sylvie ULg; Hoebeke, Maryse ULg; Vaira, Dolorès ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

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See detailSeduzione e malattia nella narrativa italiana postunitaria
Curreri, Luciano ULg

in Otto/Novecento (1992), (3/4), 53-78

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See detailThe candidate oncoprotein Bcl-3 is an antagonist of p50/NF-kappa B-mediated inhibition.
Franzoso, G.; Bours, Vincent ULg; Park, S. et al

in Nature (1992), 359(6393), 339-42

The candidate oncogene bcl-3 was discovered as a translocation into the immunoglobulin alpha-locus in some cases of B-cell chronic lymphocytic leukaemias. The protein Bcl-3 contains seven so-called ... [more ▼]

The candidate oncogene bcl-3 was discovered as a translocation into the immunoglobulin alpha-locus in some cases of B-cell chronic lymphocytic leukaemias. The protein Bcl-3 contains seven so-called ankyrin repeats. Similar repeat motifs are found in a number of diverse regulatory proteins but the motifs of Bcl-3 are most closely related to those found in I kappa B proteins in which the ankyrin repeat domain is thought to be directly involved in inhibition of NF-kappa B activity. No biological function has yet been described for Bcl-3, but it was noted recently that Bcl-3 interferes with DNA-binding of the p50 subunit of NF-kappa B in vitro. Here we demonstrate that Bcl-3 can aid kappa B site-dependent transcription in vivo by counteracting the inhibitory effects of p50/NF-kappa B homodimers. Bcl-3 may therefore aid activation of select NF-kappa B-regulated genes, including those of the human immunodeficiency virus. [less ▲]

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See detailManagement of High Turnover Osteoporosis with Calcitonin
Reginster, Jean-Yves ULg

in BONE (1992), 13(Suppl 2), 37-40

Osteoporosis, associated with a high turnover of bone and acute bone loss, occurs in a number of clinical models, such as following prolonged steroid therapy, extremity and spinal immobilisation, and ... [more ▼]

Osteoporosis, associated with a high turnover of bone and acute bone loss, occurs in a number of clinical models, such as following prolonged steroid therapy, extremity and spinal immobilisation, and often is associated with fracture. Confinement to bed and subsequent hypodynamism relating to the pain following a vertebral fracture may activate the process of high bone turnover and acute bone loss. In postmenopausal women, the acute bone loss resulting from such clinical pictures may be superimposed on to the natural course of bone loss occurring in many postmenopausal women. Salmon calcitonin, a potent inhibitor of osteoclast activity, has been shown to prevent bone loss in all clinical models of acute bone loss due to increased bone turnover and osteoclastic resorption. In addition, salmon calcitonin has a potent analgesic effect, thereby causing a reduction in bone pain and improvement in functional capacity. For these reasons, calcitonin remains a first-line therapy in bone loss related to a hyper-resorptive state. [less ▲]

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See detailEpreuves isocinétiques de fatigabilité musculaire
Croisier, Jean-Louis ULg; Lavis, C.; Crielaard, Jean-Michel ULg

in Actualités Sports et Médecine (1992), 20

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