References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailAbility of Bronchodilators to Prevent Bovine Experimental Respiratory Distress
Genicot, Bruno; Lambert, Philippe ULg; Votion, Dominique ULg et al

in Veterinary Research (1995), 26(4), 276-283

This cross-over trial involving 6 Blue Belgian double-muscled calves aimed to investigate whether ipratropium bromide inhaled alone or in combination with clenbuterol hydrochloride could prevent the ... [more ▼]

This cross-over trial involving 6 Blue Belgian double-muscled calves aimed to investigate whether ipratropium bromide inhaled alone or in combination with clenbuterol hydrochloride could prevent the dramatic clinical and pulmonary disturbances that are observed during an experimentally induced bronchoconstriction. Inhaled bronchodilators significantly influenced the clinical and functional responses of bovines subjected to a 5-hydroxytryptamine perfusion. However, despite a mean (standard error) wash-out period of 11.2 (3.1) and 7.5 (0.9) d after the 1st and the 2nd one-day challenges, respectively, first-order carry-over effects (ie those remaining from the previous treatment), effects of the period during which the treatment was allocated and interaction effects did not allow a definitive interpretation of overall treatment differences. [less ▲]

Detailed reference viewed: 42 (12 ULg)
Peer Reviewed
See detailRecension de l'ouvrage de Daniel Giovannangeli, "La passion de l'origine"
Steinmetz, Rudy ULg

in Revue Internationale de Philosophie (1995)

Detailed reference viewed: 41 (0 ULg)
Full Text
See detailAutonomie de la volonté et statut personnel
Carlier, Jean-Yves ULg

in Cahiers des droits maghrébins (1995)

Detailed reference viewed: 12 (0 ULg)
Peer Reviewed
See detailPriming production of people's names
Valentine, T.; Moore, V.; Brédart, Serge ULg

in Quarterly Journal of Experimental Psychology (1995), 48A

Detailed reference viewed: 23 (3 ULg)
Peer Reviewed
See detailLa coarctation de l'aorte isthmique (a l'exception des urgences néonatales)
Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(7), 298-304

Même quand elle est une lésion isolée, la CA est une maladie grave qui altère l'espérance de vie. Les causes de mortalité sont les complications liées à l'hypertension, la rupture spontanée au niveau des ... [more ▼]

Même quand elle est une lésion isolée, la CA est une maladie grave qui altère l'espérance de vie. Les causes de mortalité sont les complications liées à l'hypertension, la rupture spontanée au niveau des dilatations pré- et poststénotiques, au niveau des intercostales, et les anévrysmes disséquants. Le traitement chirurgical, par résection-anastomose ou interposition de greffe, introduit il y a plus de 50 ans, est obéré d'une mortalité faible chez l'adulte (1,3 %). Il ne normalise pas toutefois l'espérance de vie du patient opéré, qui reste un patient à haut risque. Les complications tardives sont proportionnelles à l'importance de l'hypertension préopératoire et à l'âge du patient au moment de l'opération. La guérison de l'hypertension est mieux assurée si le patient a été opéré dans l'enfance. Le taux de resténose est élevé pour les CA opérées avant l'âge de deux ans. Un suivi cardio-vasculaire est indispensable chez tout opéré. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Peer Reviewed
See detailThe effect of gonadal development and sex steroids on growth hormone secretion in the male tilapia hybrid (Oreochromis niloticus x O. aureus O;
Melamed, P.; Eliahu, N.; Ofir, M. et al

in Fish Physiology and Biochemistry (1995)

Detailed reference viewed: 7 (1 ULg)
Full Text
See detailDescription et interprétation stratigraphique de quatre sondages dans le Secondaire de la Gaume (Neulimont, Aubange, Saint-Mard et Toernich)
Boulvain, Frédéric ULg; Delsate, D.; Maubeuge, P. L.

in Professional Paper Belgian Geological Survey (1995), 277

Detailed reference viewed: 33 (0 ULg)
Full Text
Peer Reviewed
See detailEscape into Innocence: Ian McEwan and the Nightmare of History
Delrez, Marc ULg

in Ariel : A Review of International English Literature (1995), 26(2), 7-23

Detailed reference viewed: 109 (13 ULg)
Full Text
Peer Reviewed
See detailThe Dissociative Ionization of Carbon Dioxide below 21.22 eV. A high Resolution PIPECO spectroscopic investigation.
Locht, Robert ULg

in International Journal of Mass Spectrometry and Ion Processes (1995), 148

The photoion-photoelectron spectrum of O+, CO+ and CO2+ has been investigated under high resolution conditions. The O+ ion production is found not to be restricted to the CO2+ (C2Sigma+/g,0,0,0 ... [more ▼]

The photoion-photoelectron spectrum of O+, CO+ and CO2+ has been investigated under high resolution conditions. The O+ ion production is found not to be restricted to the CO2+ (C2Sigma+/g,0,0,0) predissociation. The (0,1,0) and (1,0,0) levels are clearly shown to be involved. The CO+ ion production involves all the vibrational states reached in the Franck-Condon region, i.e. up to (2,0,1) at 19.94 eV. The CO2+ molecular ion does not survive the predissociation in the entire range covered in the present work. [less ▲]

Detailed reference viewed: 36 (11 ULg)
Peer Reviewed
See detailHuman germinal center CD4+CD57+ T cells act differently on B cells than do classical T-helper cells.
Bouzahzah, F.; Bosseloir, A.; Heinen, Ernst ULg et al

in Developmental Immunology (1995), 4(3), 189-97

We have isolated two subtypes of helper T cells from human tonsils: CD4+CD57+ cells, mostly located in the germinal center (GC), and CD4+CD57- cells, distributed through the interfollicular areas but also ... [more ▼]

We have isolated two subtypes of helper T cells from human tonsils: CD4+CD57+ cells, mostly located in the germinal center (GC), and CD4+CD57- cells, distributed through the interfollicular areas but also present in the GC. In a functional study, we have compared the capacities of these T-cell subtypes to stimulate B cells in cocultures. In order to block T-cell proliferation while maintaining their activation level, we pretreated isolated T cells with mitomycin C prior to culture in the presence of B cells and added polyclonal activators such as PHA and Con A, combined or not with IL-2. Contrary to CD4+ CD57- cells, CD4+CD57+ cells did not markedly enhance B-cell proliferation. Even when sIgD.B cells typical of germinal center cells were tested, the CD4+CD57+ cells had no significant effect. This is in accordance with the location of these cells: They mainly occupy the light zones of the GC where few B cells divide. Even when added to preactivated, actively proliferating cells, CD4+CD57 cells failed to modulate B-cell multiplication. On the supernatants of B-cell-T-cell cocultures, we examined by the ELISA technique the effect of T cells on Ig synthesis. Contrary to CD57+ T cells, whose effect was strong, CD57- T cells weakly stimulated Ig synthesis. More IgM than IgG was generally found. Because CD57 antigen is a typical marker of natural killer cells, we tested the cytolytic activity of tonsillar CD4+CD57+ cells on K562 target cells. Unlike NK cells, neither CD4+CD57+ nor CD4+CD57- cells exhibit any cytotoxicity. Thus, germinal center CD4+CD57+ cells are not cytolytic and do not strongly stimulate either B-cell proliferation or Ig secretion. CD4+CD57- cells, however, enhance B-cell proliferation and differentiation, thus acting like the classical helper cells of the T-dependent areas. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailFast Routine Production of L-[11C-methyl]methionine with Al2O3KF
Schmitz, Frédéric; Plenevaux, Alain ULg; Del-Fiore, Guy et al

in Applied Radiation & Isotopes (1995), 46(9), 893-897

No-carrier-added (nca) L-[11C-methyl]methionine was prepared via the very fast S-alkylation of L-homocysteine adsorbed on AI203/KF with [11C]iodomethane at room temperature in ethanol. The alkylation was ... [more ▼]

No-carrier-added (nca) L-[11C-methyl]methionine was prepared via the very fast S-alkylation of L-homocysteine adsorbed on AI203/KF with [11C]iodomethane at room temperature in ethanol. The alkylation was realized with a radiochemical yield of 94 +/- 4% EOB (n = 20). More than 90% (n = 20) of the precursor L-homocysteine remained adsorbed on the solid support and was eliminated by a simple filtration. After reaction, neither racemization nor by-product were detected. The purification process was thus limited to a C18 Sep-Pak followed by an alumina Sep-Pak. The radiochemical purity measured on the final solution was shown to be > 99%. The only chemical contaminant was L-homocysteine (+ 10 µg). With this new technique, L-[11C-methyl]methionine was ready for injection within 10 min from [11C]CO2 with a specific activity ranging around 37 + 5.6 GBq (1 +/- 0.15 Ci)//tmol EOB. Through this procedure L-[11C-methyl]methionine can be prepared without preparative HPLC purification, This is an important simplification for the fast routine production of one of the most widely used radiopharmaceutical compounds for PET. [less ▲]

Detailed reference viewed: 92 (2 ULg)
Full Text
See detailAmineptine, response timing and time discrimination in the albino rat
Lejeune, Helga ULg; Hermans, Isabelle ULg; Mocaer, E. et al

in Pharmacology, Biochemistry and Behavior (1995), 51(2-3, Jun-Jul), 165-173

Experiment 1 recorded the effects of single (doses of 1, 5, 10, and 20 mg/kg) and repeated intraperitoneal injections (10 mg/kg) of amineptine (a tricyclic antidepressant drug) on the performance of ... [more ▼]

Experiment 1 recorded the effects of single (doses of 1, 5, 10, and 20 mg/kg) and repeated intraperitoneal injections (10 mg/kg) of amineptine (a tricyclic antidepressant drug) on the performance of albino rats in differential reinforcement of low rate (DRL) of 30 s, fixed-interval (FI) of 60 s, and signalled continuous reinforcement (CRF-SD) schedules. In the second experiment, the effects of repeated (10 mg/kg) and single injections (20 mg/kg) were assessed on the discrimination of the duration of auditory stimuli (2 and 8 s). A dose-related increase in response rates was observed in FI and DRL, correlating with a dose-related impairment in the temporal regulation of performance. However, the drug remained without effect on duration discrimination. In other respects, decreases in response latency in CRF-SD or duration discrimination tended to indicate that the drug improved vigilance and reactivity to extraneous significant stimuli. Interpretations in terms of sensitization, tolerance, or dependency could be discarded. Our data support the hypothesis that drug effects on temporal regulation in FI and DRL are secondary to a nonspecific activation of motor activity. They question the plausibility of an antidepressant effect of the drug in humans via modulation of a timing mechanism. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Peer Reviewed
See detailGH receptor gene TaqI RFLP and milk traits in Italian Holstein-Friesian and Simmental cattle.
Falaki, Mohamed; Renaville, Robert ULg; Sneyers, Myriam et al

in Journal of Animal Science (1995), 73(Suppl 1), 113

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailEffects of glucocorticoids and sympathomimetic agents on basal and insulin-stimulated glucose metabolism.
Paquot, Nicolas ULg; Schneiter, P.; Jequier, E. et al

in Clinical Physiology (1995), 15(3), 231-40

The mechanisms responsible for glucocorticoid-induced insulin resistance remain unclear. Glucocorticoids show several interactions with the sympatho-adrenal system which may contribute to this decrease in ... [more ▼]

The mechanisms responsible for glucocorticoid-induced insulin resistance remain unclear. Glucocorticoids show several interactions with the sympatho-adrenal system which may contribute to this decrease in insulin sensitivity: they enhance the synthesis and actions of catecholamines, but abolish insulin-induced activation of muscle sympathetic nerve activity. The present study was performed in order to investigate the effects of the interactions between glucocorticoids and the sympatho-adrenal system on insulin sensitivity. Basal and insulin-stimulated glucose metabolism was measured in healthy human subjects during four 2-h clamp studies as follows: control (C); after taking oral dexamethasone (2 mg daily) for 2 days (D); after taking oral ephedrine sulphate (40 mg daily) for 2 days (E); and after taking dexamethasone+ephedrine (D+E). Glucose uptake, production and oxidation were calculated from plasma 13C glucose and exhaled 13CO2 during constant tracer infusion of U-13C glucose. Basal glucose production, utilization and oxidation were similar in all four studies. During hyperinsulinaemia, glucose uptake was reduced by 51.5% with treatment D, by 25.9% with treatment E, and by 49.6% with D+E. Glucose oxidation was reduced by 54.0% with treatment D, by 24.0% with treatment E, and by 57.2% with D+E. Hepatic glucose production was completely suppressed in all four studies. It is concluded that both dexamethasone and ephedrine decrease insulin-mediated glucose uptake and oxidation. Co-administration of ephedrine does not suppress the glucocorticoid-induced alterations of glucose metabolism. This indicates that glucocorticoid-induced insulin resistance is not related to the inhibition of muscle sympathetic nerve activity. These results suggest instead that glucocorticoids and sympathomimetic agents may impair glucose metabolism by common actions. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailSYNTHESIS OF SIO2-TIO2 XEROGELS BY SOL-GEL PROCESS
Pirson, Anne-Marie ULg; MOHSINE, Abdel; Marchot, Pierre ULg et al

in Journal of Sol-Gel Science and Technology (1995), 4(3), 179-185

A new method to synthesize SiO2-TiO2 gels by sol-gel process has been developed. This technique uses tetraisopropylorthotitanate [Ti(O'Pr)(4)] and tetraethylorthosilicate [TEOS]: they are mixed in the ... [more ▼]

A new method to synthesize SiO2-TiO2 gels by sol-gel process has been developed. This technique uses tetraisopropylorthotitanate [Ti(O'Pr)(4)] and tetraethylorthosilicate [TEOS]: they are mixed in the same solvent and then directly hydrolysed. This one-step reaction is possible because of the use of 2-methoxyethanol, a protic polar solvent. This alcohol plays two different specific roles: it acts as a solvent as well as a stabilizer of titanium alkoxide towards the hydrolysis-precipitation reaction. So, by an accurate adjustment of the quantity of methoxyethanol in the mixture, we can control the reactivity of the titanium precursor. Monolithic and transparent xerogels were obtained whatever the composition. Three monolithic SiO2-TiO2 gels containing 20, 50 and 75 mol% of TiO2 were prepared and studied in details. By using the TG-DSC analysis, we can follow the evolution of the loss of water and organic residues. The structural evolution of gels during calcination is characterized by IR spectroscopy and X-Ray diffraction. [less ▲]

Detailed reference viewed: 125 (15 ULg)
Full Text
Peer Reviewed
See detailSOURCE STRATEGIES AND THE MEDIATIZATION OF CLIMATE-CHANGE
Mormont, Marc ULg; Dasnoy, Christine ULg

in Media, Culture & Society (1995), 17(1), 49-64

A wide approach to the problem of science-media relations is taken in this study of the visibility of science in three >European countries. Differences of national cultures within France, Germany and ... [more ▼]

A wide approach to the problem of science-media relations is taken in this study of the visibility of science in three >European countries. Differences of national cultures within France, Germany and Belgium hod the key to the analysis. This paper explores the impact on the media's representation of climate change that derives from the variations in the balance of power between the press, its scientific sources and other actors, especially pressure groups whoa have interest in how science is represented. France and Germany are shown to have very different approaches scignificantly in distinctive models of the role of media held by scinetists. These models look to be based in what is termed a "spontaneous media sociology" that frame the webs of relations between media and their sources and have a feedback effect oin them. [less ▲]

Detailed reference viewed: 268 (4 ULg)
Peer Reviewed
See detailLe développement des fonctions du langage en vue d’une meilleure intégration linguistique: le cas des Italiens de Belgique
Lucchini, Silvia ULg

in Cahiers de l'institut de linguistique de Louvain (1995), 21(1-2), 149-156

Detailed reference viewed: 6 (1 ULg)
Peer Reviewed
See detailAn approach to corrective control of voltage instability using simulation and sensitivity
Van Cutsem, Thierry ULg

in IEEE Transactions on Power Systems (1995), 10

Detailed reference viewed: 23 (1 ULg)
See detailExperimenteel onderzoek naar het brandgedrag van kolommen in gewapend beton
Dotreppe, Jean-Claude ULg; Franssen, Jean-Marc ULg; Baus, Raymond et al

in Infrastructuur in het Leefmilieu (1995), 6

Detailed reference viewed: 12 (2 ULg)
Full Text
Peer Reviewed
See detailLes troubles obsessionnels compulsifs
Triffaux, Jean-Marc ULg

in stratégie thérapeutique (1995)

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailAdvanced laparoscopic surgery for the removal of rectovaginal septum endometriotic or adenomyotic nodules.
Donnez, Jacques; NISOLLE, Michelle ULg

in Bailliere's Clinical Obstetrics & Gynaecology (1995), 9(4), 769-74

In the pelvis, three different forms of endometriosis (Donnez et al, 1992) must be considered: (1) peritoneal, (2) ovarian, (3) rectovaginal septum. By evaluation of the mitotic activity and the stromal ... [more ▼]

In the pelvis, three different forms of endometriosis (Donnez et al, 1992) must be considered: (1) peritoneal, (2) ovarian, (3) rectovaginal septum. By evaluation of the mitotic activity and the stromal vascularization, we have recently suggested (Nisolle et al, 1993) that peritoneal red lesions were the most aggressive form of the disease and progress to the so-called typical or black lesion, which must be considered as an enclosed implant surrounded by fibrosis. This type of infiltration must be clearly differentiated from the rectovaginal endometriotic nodule. Koninckx (1993) recently described three types of deep-infiltrating endometriosis: deep-infiltrating endometriosis of type I is a rather large lesion in the peritoneal cavity, infiltrating conically with the deeper parts becoming progressively smaller. It has been suggested that this type of endometriosis is caused by infiltration. In type II lesions, the main feature is that bowel is retracted over the lesion which thus becomes deeply situated in the rectovaginal septum although not actually infiltrating it. Type III lesions are the deepest and most severe. They are spherically shaped, situated deep in the rectovaginal septum, often only visible as a small typical lesion at laparoscopy or often not visible at all. This lesion is often more palpable than visible and is acutely tender if the patient is examined at the time of menstruation, and gives rise to severe dyspareunia. In our experience there are two different types of 'deep-infiltrating endometriosis': 1. True deep-infiltrating endometriosis caused by the invasion of a very active peritoneal lesion deep in the retroperitoneal space. In cases of lateral peritoneal invasion, uterosacral ligaments can be involved as well as the anterior wall of the rectosigmoid bowel junction resulting in a retraction, adhesions and secondary obliteration of the cul-de-sac. 2. Pseudo deep-infiltrating endometriosis or adenomyosis of the rectovaginal septum. This lesion originates from the rectovaginal septum tissue and consists essentially of smooth muscle with active glandular epithelium and scanty stroma. In our study, the rectovaginal nodule was histologically similar to an adenomyoma (Zaloudek and Norris, 1987). It was a circumscribed, nodular aggregate of smooth muscle, endometrial glands and endometrial stroma. As in the 'adenomyoma', secretory changes were frequently absent in 'endometriotic' rectovaginal nodules. The invasion of the muscle by a very active glandular epithelium, without stroma, proved that the stroma is not necessary for invasion in this particular type of pathology called adenomyosis. In some instances, it can be seen that the vaginal pluristratified epithelium was replaced by a glandular epithelium. The fact that ciliated cells were present and the co-expression of both vimentin and cytokeratin (Donnez and Nisolle, personal communication) proved the Mullerian origin of the nodule, where certain histological characteristics are completely different to those observed in peritoneal lesions (Nisolle et al, 1990). In our series, deep fibrotic tissue assumed to contain endometriosis was excised or vaporized from the anterior rectum with the aid of multiple rectovaginal examinations. Cul-de-sac dissection was followed by excision of deep fibrotic endometriosis, without cul-de-sac reconstruction. In three cases, the bowel lumen was entered. A comprehensive laparoscopic procedure, while not eradicating all the endometriosis, may result in considerable pain relief or a desired pregnancy. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Peer Reviewed
See detailActivation of leucocytes after prolonged physical exercise
Bury, Thierry ULg; PIRNAY, Freddy ULg

in Mediators of Inflammation (1995), 4

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailStructure and characterization of isopyoverdin from Pseudomonas putida BTP1 and its relation to the biogenetic pathway leading to pyoverdins.
Jacques, Philippe ULg; Ongena, MARC ULg; Gwose, I. et al

in Zeitschrift für Naturforschung. C, Journal of Biosciences (1995), 50(9-10), 622-9

Pyoverdin type siderophores produced by six fluorescent Pseudomonas strains isolated from different rhizospheres were purified and characterized. The purified ferri-pyoverdins were tested for their ... [more ▼]

Pyoverdin type siderophores produced by six fluorescent Pseudomonas strains isolated from different rhizospheres were purified and characterized. The purified ferri-pyoverdins were tested for their ability to promote the growth of other strains grown under iron deficiency conditions. Only the one obtained from Pseudomonas putida BTP1 did not act as a growth promoter. The structure of the BTP1 siderophore was elucidated by spectroscopic methods and degradation studies. It turned out that it contains a chromophore which differs from the one typical for pyoverdins insofar as it carries the carboxyl group in 3- rather than in 1-position ((3S)-5-amino-1,2-dihydro-8,9-dihydroxy-3H-pyrimido[1,2a]quinoline-3- carboxylic acid). The amino group of the chromophore is substituted with the 5-carboxyl group of L-glutamic acid and its carboxyl group with the N-terminus of the peptide L-Asp-L-Ala-L-Asp-D-N5-Ac-N5-OH-Orn-L-Ser-L-c-N5-OH-Orn. This isopyoverdin fits into the biogenetic scheme which postulates ferribactins as the precursors of pyoverdins. [less ▲]

Detailed reference viewed: 25 (9 ULg)
Full Text
Peer Reviewed
See detailBehavior of interchromatin granules during the cell cycle.
Thiry, Marc ULg

in European Journal of Cell Biology (1995), 68(1), 14-24

We investigated at the ultrastructural level, by different cytochemical and immunocytological approaches, the behavior of interchromatin granules (IGs) during interphase and mitosis in two cell lines (HEp ... [more ▼]

We investigated at the ultrastructural level, by different cytochemical and immunocytological approaches, the behavior of interchromatin granules (IGs) during interphase and mitosis in two cell lines (HEp-2 and Ehrlich tumor cells). Identical results were found in all two cell types. In interphase cells, IGs group into irregular clusters of varying size. They are frequently associated with coiled bodies and homogeneous fibrillar bodies. Analysis of serial sections reveals that IG clusters occupy distinct regions within the nucleoplasm. During prophase, the aggregation of granules in these clusters gives rise to compact, spherical, granular structures. These disperse in the mitotic cytoplasm at the breakdown of the nuclear envelope. At early telophase, some of them come into close contact with the periphery of reforming nuclei. IG clusters reappear in the daughter nuclei only after the chromosomes have decondensed during late telophase. Concomitantly, the cytoplasmic granular structures disappear. During the cell cycle, IG are silver-stainable and EDTA-positive. They are also constantly labeled by the polyadenylate nucleotidyl transferase-immunogold technique for detecting RNA. These results support the view that IGs persist throughout the whole cell cycle. [less ▲]

Detailed reference viewed: 21 (3 ULg)
See detailStochastic generation of precipitation and effect on vegetation net primary production
Hubert, Benoît ULg; François, Louis ULg; Warnant, Pierre ULg

in Global Energy and Water Cycle Experiment news (1995), 5

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailTreatment of dysfunctional bleeding and fibroids by advanced endoscopic techniques with the Nd:YAG laser: from the present to the future.
Donnez, Jacques; Polet, Roland; Anaf, V. et al

in Bailliere's Clinical Obstetrics & Gynaecology (1995), 9(2), 329-45

Both the electrical current of the resectoscope and the energy of the Nd:YAG laser have been effective tools in the destruction of endometrial tissue to a sufficient depth to avoid regeneration. GnRH ... [more ▼]

Both the electrical current of the resectoscope and the energy of the Nd:YAG laser have been effective tools in the destruction of endometrial tissue to a sufficient depth to avoid regeneration. GnRH-agonist therapy effects a decrease in the total uterine cavity area which facilitates surgical treatment and reduces the risk of fluid overload syndrome. The recurrence rate of meno/metrorrhagia is higher when the uterine cavity is more than 10 cm2. The use of GnRH-agonists represents an adjunct for preoperative reduction of submucosal myomas so that subsequent hysteroscopic myomectomy is possible. A two-step hysteroscopic therapy combined with GnRH-agonist therapy is performed when the largest portion of the submucosal myoma is located in the uterine wall. In cases of numerous submucosal and intramural myomas, a laparoscopic supracervical hysterectomy is performed because of the high risk of recurrence after the hysteroscopic procedure. [less ▲]

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailBiotinidase Km-variants: detection and detailed biochemical investigations
Suormala, T.; RAMAEKERS, Vincent ULg; Schweitzer, S. et al

in Journal of inherited metabolic disease (1995), 18(6), 689-700

We describe a simple method for the detection of biotinidase Km-variants and detailed biochemical investigations in 5 such patient. They were detected among 103 patients with plasma biotinidase activity ... [more ▼]

We describe a simple method for the detection of biotinidase Km-variants and detailed biochemical investigations in 5 such patient. They were detected among 103 patients with plasma biotinidase activity which ranged from undetectable to 30% of the mean normal value. Two different types of biotinidase Km-variants were found. (1) In 3 infants biotinidase had a single 105-430-fold elevated Km for biocytin. Biotinidase showed very low activities (0.2-4% of the mean normal value) in the routine colorimetric assay and was not functional in vivo. Accordingly, these patients presented with classical clinical illness. (2) In two patients biotinidase showed biphasic kinetics indicating the presence of one component with a normal Km and reduced Vmax (1.7% and 12%), and another with 330- and 59-fold elevated Km, respectively. In these two patients, biotinidase proved to be at least partially functional in vivo. However, the first patient developed severe symptoms and biotin deficiency late, at the age of 10-15 years, and the second had marginal biotin deficiency at the age of 2 years but no clinical symptoms. Comparative studies revealed that both patients had more severe biotin deficiency than age-matched patients with similar levels of residual biotinidase activity and a single normal Km. Therefore, all patients with residual biotinidase activity should be evaluated for the presence of a Km-mutation, since such patients should be treated with biotin. These can easily be detected by including a second substrate concentration (1.5 mmol/L) in the routine colorimetric biotinidase assay which is performed with 0.15 mmol/L biotin. Increased activity with the higher substrate concentration indicates the presence of a Km-mutation. Detailed kinetic studies are needed to evaluate the distinct forms of Km-variants. [less ▲]

Detailed reference viewed: 15 (0 ULg)
Peer Reviewed
See detailPostweaning housing conditions and partner preference and sexual behavior of neonatally ATD-treated male rats.
Bakker, Julie ULg; van Ophemert, J.; Slob, A. K.

in Psychoneuroendocrinology (1995), 20(3), 299-310

Male rats were neonatally treated with cholesterol or a substance that blocks the aromatization of testosterone to estradiol (1,4,6-androstatriene-3,17-dione: ATD). At weaning (21 days) they were either ... [more ▼]

Male rats were neonatally treated with cholesterol or a substance that blocks the aromatization of testosterone to estradiol (1,4,6-androstatriene-3,17-dione: ATD). At weaning (21 days) they were either housed alone or in small groups (2-3 animals) and tested for partner preference behavior (PPB) in adulthood. Choice was between an estrous female and an active male (Part I) and between an estrous female and an ATD-male (Part II). Tests were carried out in a 3-compartment box. Social isolation did not have major effects on PPB except when sexual interaction with the stimulus animals was prevented (Part I). In this case, isolates (ATD and control) showed higher preference scores (PS) for the estrous female and spent less time in the empty middle compartment. When the choice was between an estrous female and an ATD-male, partner PS decreased in all males, most clearly in ATD-males. The latter animals spent more time with the stimulus ATD-male than they had done in previous PPB tests with the normal stimulus male. In contrast to partner preference behaviors, sexual behavior was clearly affected by social isolation. Isolates (ATD and control) displayed lower frequencies of mounts and intromissions. These effects persisted over consecutive tests. Ejaculation was not affected. In conclusion, the present results confirm earlier findings about the significance of neonatal endocrine conditions for the organization of adult PPB in male rats. The presence or absence of social conspecifics after weaning appears to have little influence on adult PPB. [less ▲]

Detailed reference viewed: 2 (0 ULg)
Full Text
Peer Reviewed
See detailStreptomyces K15 active-site serine DD-transpeptidase: specificity profile for peptide, thiol ester and ester carbonyl donors and pathways of the transfer reactions.
Grandchamps, Jacqueline; Nguyen-Distèche, Martine ULg; Damblon, Christian ULg et al

in Biochemical Journal (1995), 307(Pt 2), 335-339

The Streptomyces K15 transferase is a penicillin-binding protein presumed to be involved in bacterial wall peptidoglycan crosslinking. It catalyses cleavage of the peptide, thiol ester or ester bond of ... [more ▼]

The Streptomyces K15 transferase is a penicillin-binding protein presumed to be involved in bacterial wall peptidoglycan crosslinking. It catalyses cleavage of the peptide, thiol ester or ester bond of carbonyl donors Z-R1-CONH-CHR2-COX-CHR3-COO- (where X is NH, S or O) and transfers the electrophilic group Z-R1-CONH-CHR2-CO to amino acceptors via an acyl-enzyme intermediate. Kinetic data suggest that the amino acceptor behaves as a simple alternative nucleophile at the level of the acyl-enzyme in the case of thiol ester and ester donors, and that it binds to the enzyme.carbonyl donor Michaelis complex and influences the rate of enzyme acylation by the carbonyl donor in the case of amide donors. Depending on the nature of the scissile bond, the enzyme has different requirements for substituents at positions R1, R2 and R3. [less ▲]

Detailed reference viewed: 21 (3 ULg)
Peer Reviewed
See detailLe rôle de l'industrie de l'assurance dans le pilotage de la sécurité privée et de la politique de prévention
Lemaître, André ULg

in Déviance et Société (1995), 19(N°2), 159-168

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailConformational Analysis Of Non-Sulfonylurea Hypoglycemic Agents Of The Meglitinide Family
Lins, Laurence ULg; Brasseur, Robert ULg; Malaisse, Wj.

in Biochemical Pharmacology (1995), 50(11), 1879-84

Detailed reference viewed: 14 (2 ULg)
Peer Reviewed
See detailInfection respiratoire équine à Bordetella bronchiseptica
Vandevenne, S.; Caudron, I.; Serteyn, Didier ULg et al

in Annales de Médecine Vétérinaire (1995), 139

Detailed reference viewed: 13 (0 ULg)
Peer Reviewed
See detailSerological and cutaneous testing of bovine tuberculosis with the A60 antigen complex from Mycobacterium bovis, strain Calmette-Guérin
Saegerman, Claude ULg

in Preventive Veterinary Medicine (1995), 23

A60, a major thermostable macromolecular antigen complex of Mycobacterium bovis strain Calmette-Guerin (BCG), is immunodominant in tuberculosis and able to elicit both humoral and cellular immune ... [more ▼]

A60, a major thermostable macromolecular antigen complex of Mycobacterium bovis strain Calmette-Guerin (BCG), is immunodominant in tuberculosis and able to elicit both humoral and cellular immune reactions in infected hosts. A60-based ELISA and cutaneous tests have been used, in conjunction with the PPD-based skin reaction, in a control group of healthy animals, and in a herd including tuberculous animals. Cutaneous testing with A60 yielded results comparable with those with PPD: both were negative with control cattle and positive with infected animals. Moreover, comparative cutaneous testing with avian tuberculin yielded similar results with PPD and A60. When animals from the infected herd were tested with both avian and bovine sensitins, 54% of cattle were diagnosed as fully positive, 26% suspect, and 20% negative. Serological analysis with the A60-ELISA of part of the infected herd yielded 74% positive, 21% suspect and 5% negative results. Thus, positivity was 74% for serological analysis and 54% for cutaneous testing, whereas positive plus suspect results were 95% for serological analysis and 80% for cutaneous testing. It can be concluded that A60 can be used in place of PPD for cutaneous testing in cattle, and that the diagnostic value of the A60-ELISA is superior to that of the PPD-cutaneous test. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailRhythmic and Electrophysiological Study after Dynamic Cardiomyoplasty
RADERMECKER, Marc ULg; Waleffe, André ULg; Gobin, Eric ULg et al

in Pacing & Clinical Electrophysiology (1995), 18(5, Pt 1), 965-72

To question the possible proarrhythmic effects of cardiomyoplasty (CMP), six adult goats were submitted to rhythmic and electrophysiological (EP) study 15 days before and 8 months after a posteroanterior ... [more ▼]

To question the possible proarrhythmic effects of cardiomyoplasty (CMP), six adult goats were submitted to rhythmic and electrophysiological (EP) study 15 days before and 8 months after a posteroanterior clockwise CMP procedure using Medtronic Cardiomyostimulator (CMS) (SP1005) and electrodes (SP5528) and completion of a progressive stimulation protocol. Pre and postoperative screening included a surface ECG, 24-hour Holter monitoring, high amplitude and filtered QRS averaging, and invasive EP study performed in the postoperative period with the CMS "ON" and "OFF." One-hour Holter recording with desynchronization of the CMS was obtained. Comparison of pre and postoperative ECG and rhythmic data showed no significant difference. High amplitude QRS averaging did not evidence meeting the usual criteria of late potentials. EP values were stable in both conditions and the aggressive EP program did not show evidence of increased susceptibility to arrhythmias. Asynchronous cardiomyostimulation did not induce arrhythmias. Our data strongly suggest that provided meticulous surgical technique is used, CMP does not significantly interfere with the electrical characteristics of the normal goat heart. The procedure, despite the disturbances it provokes, does not seem to be arrhythmogenic. The function of the CMS was always appropriate, even under stressful EP conditions. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailPhospholipid-Binding And Lecithin-Cholesterol Acyltransferase Activation Properties Of Apolipoprotein-A-I Mutants
Holvoet, P.; Zhao, Za.; Vanloo, B. et al

in Biochemistry (1995), 34(41), 13334-42

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space ... [more ▼]

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space of Escherichia coli, were studied. The rate of turbidity decrease following mixing of apo A-I(delta Ala190-Gln243) with dimyristoylphosphatidylcholine (DMPC) vesicles at 23 degrees C was 10-fold lower than that of the other apo A-I proteins, confirming that the carboxy-terminal region of apo A-I plays a role in rapid lipid binding. The Stokes radii of reconstituted high-density lipoproteins (rHDL), containing dipalmitoylphosphatidylcholine and cholesterol, were larger for the three apo A-I mutants [6.3 nm for apo A-I(delta Leu44-Leu126), 6.1 nm for apo A-I(delta Glu139-Leu170), and 6.5 nm for apo A-I(delta Ala190-Gln243)] than for intact apo A-I (5.0 nm). The mutant rHDL all contained 4 apo A-I molecules per particle as compared to 2 for intact apo A-I. Circular dichroism measurements revealed 8 alpha-helices per apo A-I molecule, 5 per apo A-I(delta Leu44-Leu126), 6 per apo A-I(delta Glu139-Leu170), and 4 per apo A-I(delta Ala190-Gln243) molecule as compared to predicted values of 8, 5, 6, and 6 alpha-helices, respectively. [less ▲]

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailInsulinotropic action of (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate. II. Ionophoretic and conformational aspects.
Malaisse, W. J.; Nadi, A. B.; Malaisse-Lagae, F. et al

in General Pharmacology (1995), 26(6), 1319-25

1. The non-sulphonylurea insulinotropic agent sodium (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) was found to display calcium ionophoretic activity in an artificial ... [more ▼]

1. The non-sulphonylurea insulinotropic agent sodium (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) was found to display calcium ionophoretic activity in an artificial membrane model. 2. Conformation analysis indicated that a complex between calcium and KAD-1229, with a 1:2 stoichiometry, indeed displays favourable attributes for ionophoretic activity across a hydrophobic environment. 3. It is speculated that the ionophoretic property of KAD-1229 might participate to the remodelling of cationic fluxes evoked by this insulinotropic agent in pancreatic islet cells. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailExpertise scientifique et action publique : le cas du changement climatique dans trois pays européens
Mormont, Marc ULg; Dasnoy, Christine ULg

in Natures Sciences Sociétés (1995), 3(&), 16-25

L'expertise scientifique du changement climatique fait l'objet d'une réception très différente en France, en Allemagne et en Belgique. cet état de fait semble lié à la fois à des configurations politiques ... [more ▼]

L'expertise scientifique du changement climatique fait l'objet d'une réception très différente en France, en Allemagne et en Belgique. cet état de fait semble lié à la fois à des configurations politiques différentes, à des procédures spécifiques mais aussi aux stratégies des scientifiques lesquelles dépendent de leur anticipation de cette réception. Cette stratégie des "sources" d'information ne laisse pas de poser des questions sur l'expertise. [less ▲]

Detailed reference viewed: 94 (6 ULg)
Peer Reviewed
See detailEffects of a new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism.
Oelkers, W.; Foidart, Jean-Michel ULg; Dombrovicz, N. et al

in Journal of Clinical Endocrinology and Metabolism (1995), 80(6), 1816-21

Combined hormonal oral contraceptives (OCs) may lead to a mild rise in blood pressure and body weight. In rare instances, large increments in blood pressure are measured. We investigated the effect of a ... [more ▼]

Combined hormonal oral contraceptives (OCs) may lead to a mild rise in blood pressure and body weight. In rare instances, large increments in blood pressure are measured. We investigated the effect of a combination of ethinyl estradiol (EE) plus a progestogen with antimineralocorticoid, i.e. natriuretic, properties [Drospirenone (DRSP)] on body weight, blood pressure, the renin-aldosterone system, atrial natriuretic factor, plasma lipids, and glucose tolerance. It is anticipated that this will lead to the development of an OC that does not raise body weight or blood pressure. Four groups of 20 women each received 30 micrograms EE plus 3 mg DRSP (group A), 20 micrograms EE plus 3 mg DRSP (group B), 15 micrograms EE plus 3 mg DRSP (group C), and, as a control OC, 30 micrograms EE plus 150 micrograms levonorgestrel (Microgynon, Schering; group D) for 6 months. During the OC-free control cycles before and after treatment and throughout treatment, the target parameters were measured. Between the pretreatment cycle and the sixth treatment cycle, mean body weight fell by 0.8 to 1.7 kg in groups A, B, and C (P < 0.05 vs. D), whereas it rose by 0.7 kg in group D. Systolic and diastolic blood pressures fell by 1-4 mm Hg in groups A, B, and C (significant for A and C vs. D) and increased by 1-2 mm Hg in group D. Renin substrate rose equally in all groups (P < 0.05), whereas PRA and plasma aldosterone rose significantly only in the DRSP groups, presumably due to sodium loss. In the DRSP groups, high density lipoprotein cholesterol rose (P < 0.05), in contrast to group D. Low density lipoprotein cholesterol fell slightly (P > 0.05), whereas triglyceride levels showed a stronger increase in the DRSP groups (P < 0.05) than in group D. All groups attained good cycle control; group A had the best. Side-effects were minimal. To our knowledge, this is the first report on a combined OC that leads to a small decrease in body weight and blood pressure. It may be especially beneficial for women susceptible for a gain in weight and a rise in blood pressure. The potential of a new oral contraceptive (OC) containing drospirenone (DRSP) to avert the moderate increases in body weight and blood pressure often associated with use of existing combined OCs was investigated in a study of four groups of 20 German women each. Group A received 30 mcg of ethinyl estradiol (EE) and 3 mg of DRSP, Group B was administered 20 mcg of EE and 3 mg of DRSP, Group C received 15 mcg of EE and 3 mg of DRSP, and Group D was given a standard OC containing 30 mcg of EE and 150 mcg of levonorgestrel. Between the pretreatment cycle and the last (sixth) treatment cycle, mean body weight fell by 0.8-1.7 kg in Groups A, B, and C, but rose by 0.7 kg in Group D. Systolic and diastolic blood pressures fell by 1-4 mm Hg in Groups A, B, and C and rose by 1-2 mm Hg in Group D. Renin substrate rose equally in all four groups, while plasma renin activity, plasma aldosterone, and high density lipoprotein cholesterol rose significantly only in the three DRSP groups and serum triglyceride levels were significantly higher in Group D than in the three DRSP groups. Glucose tolerance increases were similar in all four groups. Finally, all groups--but especially Group A--experienced good cycle control and there were no serious side effects. These findings suggest that a combined OC containing DRSP may be especially beneficial for women who have a tendency to gain weight or experience a rise in blood pressure while taking OCs. [less ▲]

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailViability of cloned bovine embryos after one or two cycles of nuclear transfer and in vitro culture
Ectors, Fabien ULg; Delval, Alain; Smith, Lawrence et al

in Theriogenology (1995), 44

We described an exclusively in vitro procedure for cloning and recloning bovine embryos. Embryos obtained by IVM/IVF/IVC developed to the morula stage were used as blastomere donors in cunjunction with ... [more ▼]

We described an exclusively in vitro procedure for cloning and recloning bovine embryos. Embryos obtained by IVM/IVF/IVC developed to the morula stage were used as blastomere donors in cunjunction with IVM recipient oocytes. Reconstructed embryos were developed in vitro in co-culture using bovine oviductal epithelial cells. The resulting morulae were used as donors for recloning under the same experimental conditions. No significant difference was observed between cloning and recloning in terms of development (rates of blastocysts: 12.9 versus 14.9%), in the number of nuclei per blastocyst (63.8 versus 49.1), or in pregnancy rates (35.7 versus 33.3%). The high variability observed between replicates and the correlation between results in first and second cycle nuclear transfer may suggest an inherant potential of individual donor embryos to support development by cloning [less ▲]

Detailed reference viewed: 16 (5 ULg)
Full Text
See detailDinant/Falmignoul: Abri du Pape
Noiret, Pierre ULg

in Chronique de l'Archéologie wallonne (1995), 3

Detailed reference viewed: 20 (0 ULg)
Peer Reviewed
See detailTHEORY OF THE THERMAL-CONDUCTIVITY OF RE AL-2 COMPOUNDS
Rassili, Ahmed ULg; Ausloos, Marcel ULg

in Journal of Magnetism & Magnetic Materials (1995), 147(3), 341-345

On the basis of the variational method for transport coefficients we have calculated the thermal conductivity of RE Al-2-like systems as a function of temperature. The low-temperature limit obeys ... [more ▼]

On the basis of the variational method for transport coefficients we have calculated the thermal conductivity of RE Al-2-like systems as a function of temperature. The low-temperature limit obeys Matthiessen's rule 1/kappa = 1/kappa(ph) + 1/kappa(s) + 1/kappa(imp) where the three components are the contributions arising from e(-)-phonon, e(-)-localized spin and e(-)-impurity interactions, respectively. The temperature dependence of each term has been calculated, as well as the superposition of all three. The influence of the physical parameters (spin value, Debye temperature, cut-off wave vector, Fermi energy, etc.) is shown. The theory is in good agreement with reported data for GdAl2. [less ▲]

Detailed reference viewed: 20 (6 ULg)
Peer Reviewed
See detailDes histoires du cinéma en images et en sons
Belloi, Livio ULg

in Iris - Revue de théorie de l'image et du son/A Journal of Theory on Image and Sound (1995), 19(automne), 75-98

Etude de quelques fictions réflexives (dont "Singin' in the Rain" de Stanley Donen et Gene Kelly) au travers desquelles, se mettant au miroir, le cinéma réfléchit sur sa propre histoire et sur ses jalons ... [more ▼]

Etude de quelques fictions réflexives (dont "Singin' in the Rain" de Stanley Donen et Gene Kelly) au travers desquelles, se mettant au miroir, le cinéma réfléchit sur sa propre histoire et sur ses jalons essentiels. [less ▲]

Detailed reference viewed: 34 (10 ULg)
Full Text
Peer Reviewed
See detailProximal Migration of Vena Caval Filters: Report of Two Cases with Operative Retrieval
DEFRAIGNE, Jean ULg; Vahdat, Olivier; Lacroix, Hendrik et al

in Annals of Vascular Surgery (1995), 9(6), 571-5

Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle ... [more ▼]

Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle, and in the second one the filter was found in the pulmonary artery. Both filters were retrieved under cardiopulmonary bypass via an incision in the right atrium and the pulmonary artery, respectively. These two observations underscore the risk of increased unwarranted indications and consequent higher complication rates of vena caval filters. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Peer Reviewed
See detailSIMULTANEOUS OBSERVATIONS OF THE SATURNIAN AURORA AND POLAR HAZE WITH THE HST/FOC
Gérard, Jean-Claude ULg; DOLS, V.; Grodent, Denis ULg et al

in Geophysical Research Letters (1995), 22(20), 2685-2688

Near simultaneous observations of the Saturnian H-2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the post-COSTAR Hubble ... [more ▼]

Near simultaneous observations of the Saturnian H-2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the post-COSTAR Hubble Space Telescope. The auroral observations cover a complete rotation of the planet and, when co-added, they reveal the presence of an auroral emission near 80 degrees N with a brightness of about 150 kR of total H-2 emission. The maximum vertical optical depth at 210 nm is found to be located similar to 5 degrees equatorward of the auroral emission zone. The haze particles are presumably formed by hydrocarbon aerosols initiated by H-2(+) auroral production. In this case, the 3 x 10(10) W of H-2 emission observed with the FOG, combined with the deduced haze optical depth requires an efficiency of aerosol formation of about 7%. This result indicates that auroral production of hydrocarbon aerosols is a viable source of high-latitude haze. [less ▲]

Detailed reference viewed: 20 (4 ULg)
Full Text
Peer Reviewed
See detailThe importance of liposomes as models and tools in the understanding of photosensitization mechanisms
Hoebeke, Maryse ULg

in Journal of Photochemistry and Photobiology B : Biology (1995), 28(3), 189-196

The various applications of liposomes in understanding photosensitization are described in this paper, with particular emphasis on the various kinds of information that these models allow to obtain in ... [more ▼]

The various applications of liposomes in understanding photosensitization are described in this paper, with particular emphasis on the various kinds of information that these models allow to obtain in phototherapy. Liposomes are simple vesicles in which an aqueous phase is enclosed by a phospholipidic membrane. They are suitable models mimicking specific situations occurring <br />m vivo and they allow study of the influence of physieochemieal, photobioiogieal and biochemical factors on the uptake of photosensitizers by tissues, their mechanisms of action and the subsequent photoinduced tumor necrosis. Moreover, solubilization of the sensitizer into the bilayer seems to improve its tumoral selectivity and its photodynamic efficiency. [less ▲]

Detailed reference viewed: 17 (8 ULg)
Peer Reviewed
See detailLes allogreffes veineuses pour sauvetage des membres inférieurs: espoirs et réalité
VAN DAMME, Hendrik ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(10), 433-42

La veine saphène interne est le matériel de pontage de premier choix pour les revascularisations de membres au-dessous du pli de l'aine. Elle n'est néanmoins pas disponible chez près de 20 % des candidats ... [more ▼]

La veine saphène interne est le matériel de pontage de premier choix pour les revascularisations de membres au-dessous du pli de l'aine. Elle n'est néanmoins pas disponible chez près de 20 % des candidats à une chirurgie infra-inguinale, soit parce qu'elle a déjà été utilisée antérieurement, soit à cause de varicose ou d'un calibre trop petit. Ces dernières années ont vu apparaître dans la littérature un regain d'intérêt pour la veine saphène allologue, prélevée chez un donneur d'organes ou préparée à partir de segments de veine saphène strippée. Les auteurs en discutent les avantages théoriques et les modalités de conservation. Des travaux expérimentaux ont été suivis par des séries cliniques encore limitées en nombre et en temps de suivi. Les auteurs en discutent les résultats publiés. Une courte série (12 cas) dans notre département est décrite. Cette expérience limitée et une revue exhaustive de la littérature permettent de conclure que les allogreffes veineuses sont à réserver pour les sauvetages de jambes (lésions infrapoplitées) lorsque la veine autologue n'est pas disponible, en tant que solution de dernier recours. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailReprésentations de la justice sociale - L'exemple de la Belgique francophone
Jacquemain, Marc ULg

in Année Sociologique (L') (1995), 45

Lorsqu'on analyse les réponses à une batterie de questions sur la justice sociale en Belgique, on voit apparaître trois facteurs, qui ne correspondent pas à des "valeurs" mais plutôt à des "thématiques ... [more ▼]

Lorsqu'on analyse les réponses à une batterie de questions sur la justice sociale en Belgique, on voit apparaître trois facteurs, qui ne correspondent pas à des "valeurs" mais plutôt à des "thématiques transversales". Le premier facteur concerne l'inclusion : la justice est-elle due, par exemple aux immigrés ou aux chômeurs ? Le deuxième facteur concerne le rôle géénral de l'Etat social. Le troisième facteur concerne la dimension première ou subsidiaire de la sécurité sociale. [less ▲]

Detailed reference viewed: 42 (7 ULg)
Full Text
Peer Reviewed
See detailResults of an Exclusion Technique for Treatment of Abdominal Aortic Aneurysm
Marnette, J.M.; CREEMERS, Etienne ULg; TROTTEUR, Geneviève ULg et al

in Cardiovascular Surgery (1995), 3(1), 26-9

An exclusion technique for the treatment of abdominal aortic aneurysm was used in six patients considered to be at high operative risk mainly because of chronic pulmonary disease. There were no deaths or ... [more ▼]

An exclusion technique for the treatment of abdominal aortic aneurysm was used in six patients considered to be at high operative risk mainly because of chronic pulmonary disease. There were no deaths or immediate major complications. Thrombosis of the aneurysm was achieved in four of the six patients. However, in three cases, repeated percutaneous embolization was required to produce thrombosis. One patient developed a secondary rupture of a persisting infrarenal sac resulting from a patent inferior mesenteric artery. This patient was successfully managed by ligature of the infrarenal portion of the abdominal aorta through a median laparotomy. This study emphasizes the limits and the risks of the exclusion technique. [less ▲]

Detailed reference viewed: 30 (0 ULg)
Peer Reviewed
See detailSU (3) scaled effective lagrangians for a hot and strange system
Jaminon, Martine ULg; Van Den Bossche, Bruno

in Nuclear Physics A (1995), 582

We construct two effective lagrangians which reproduce the explicit flavor SU(3) symmetry breaking and the trace and axial anomalies of QCD. All analytical expressions are derived for a hot strange matter ... [more ▼]

We construct two effective lagrangians which reproduce the explicit flavor SU(3) symmetry breaking and the trace and axial anomalies of QCD. All analytical expressions are derived for a hot strange matter but the results are only shown for zero baryonic density. We study the coupling of the quark condensates (u and s) to the gluon condensate. We also consider the temperature behavior of the pion and of the kaon masses. We show that the results crucially depend on the choice of the two free parameters of the model: the chiral transition can be of first or of second order; the coupling between the gluon and the quark condensates can be large or not; the meson masses can increase or decrease with temperature. The introduction of the QCD trace anomaly in the SU(3) NJL model kills the predictive character of the NJL. [less ▲]

Detailed reference viewed: 17 (6 ULg)
Peer Reviewed
See detailAbsence of tiGh effect on adaptability to brackish water in Tilapia (Oreochromis niloticus)
Auperin, B.; Leguen, I.; Rentier-Delrue, Françoise ULg et al

in General and Comparative Endocrinology (1995)

The aim of this study was to investigate the possible role of growth hormone in the adaptation of tilapia (Oreochromis niloticus) to brackish water and to analyze its interactions with prolactin in this ... [more ▼]

The aim of this study was to investigate the possible role of growth hormone in the adaptation of tilapia (Oreochromis niloticus) to brackish water and to analyze its interactions with prolactin in this process. Plasma levels of growth hormone do not change upon transfer to brackish water. Treatment of intact tilapia in fresh water with growth hormone prior to transfer did not enable the fish to preadapt to brackish water: the duration of the hydromineral imbalance after transfer was the same in treated animals and controls. The major osmoregulatory role of prolactin in fresh water led us to test the hypothesis that prolactin might antagonize the effect of growth hormone on adaptation to brackish water. Growth-hormone-treated hypophysectomized animals, however, exhibited no increased osmoregulatory capacity as compared to hypophysectomized controls, confirming the absence of a growth-hormone-related osmoregulatory effect. When prolactin and growth hormone were coinjected, growth hormone also proved unable to oppose the Na+ retaining effect of prolactin, in both brackish and fresh water. Surprisingly, hypophysectomized animals adapt better to brackish water than do sham-operated animals. This result is discussed in light of the effects of prolactin and cortisol on osmoregulation in brackish water and we suggest that an important event which allows O. niloticus to adapt to hyperosmotic environment is the reduction of plasma PRL upon transfer to brackish water. [less ▲]

Detailed reference viewed: 28 (6 ULg)
Peer Reviewed
See detailA comprehensive analysis of mid-term voltage stability
Van Cutsem, Thierry ULg; Jacquemart, Yannick; Marquet, Jean-Noël et al

in IEEE Transactions on Power Systems (1995), 10

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailLa physiologie de la valvule mitrale
RADERMECKER, Marc ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(7), 289-91

Faisant suite à une revue de l'anatomie de l'appareil mitral, les auteurs envisagent la physiologie de la valvule mitrale en étudiant les quatre phénomènes distincts que sont la contraction auriculaire ... [more ▼]

Faisant suite à une revue de l'anatomie de l'appareil mitral, les auteurs envisagent la physiologie de la valvule mitrale en étudiant les quatre phénomènes distincts que sont la contraction auriculaire, la dynamique de l'anneau, les mouvements de la valvule et la dynamique du flux mitral, ainsi que le jeu des muscles papillaires. Cette subdivision didactique ne doit pas estomper le fait que c'est l'intégration de ces phénomènes qui contribue à l'efficacité de la valvule. [less ▲]

Detailed reference viewed: 48 (8 ULg)
Full Text
Peer Reviewed
See detailLight reflection model for lighting applications
Embrechts, Jean-Jacques ULg

in Lighting Research & Technology (1995), 27(4)

Detailed reference viewed: 23 (5 ULg)
Full Text
Peer Reviewed
See detailHYDRODYNAMIC SIMULATIONS OF GALAXY FORMATION .1. DISSIPATION AND THE MAXIMUM MASS OF GALAXIES
Thoul, Anne ULg; WEINBERG, D. H.

in Astrophysical Journal (1995), 442(2), 480-491

We describe an accurate, one-dimensional, spherically symmetric Lagrangian hydrodynamics/gravity code, designed to study the effects of radiative cooling and photoionization on the formation of ... [more ▼]

We describe an accurate, one-dimensional, spherically symmetric Lagrangian hydrodynamics/gravity code, designed to study the effects of radiative cooling and photoionization on the formation of protogalaxies. The code can treat an arbitrary number of fluid shells (representing baryons) and collisionless shells (representing cold dark matter). As a test of the code, we reproduce analytic solutions for the pulsation behavior of a poly-trope and for the self-similar collapse of a spherically symmetric, cosmological perturbation. In this paper we concentrate on the effects of radiative cooling, examining the ability of collapsing perturbations to cool within the age of the universe. In contrast to some studies based on order-of-magnitude estimates, we find that cooling arguments alone cannot explain the sharp upper cutoff observed in the galaxy luminosity function. [less ▲]

Detailed reference viewed: 14 (3 ULg)
Peer Reviewed
See detailInfluence du risque suicidaire et du desespoir sur l'amplitude de l'onde P300 dans la depression majeure.
Urcelay-Zaldua, I.; Hansenne, Michel ULg; Ansseau, Marc ULg

in Neurophysiologie Clinique = Clinical Neurophysiology (1995), 25(5), 291-6

P300 amplitude represents a useful tool to assess information processing in normal and psychopathological subjects. In depressive disorders, many studies have shown a decrease of P300 amplitude and an ... [more ▼]

P300 amplitude represents a useful tool to assess information processing in normal and psychopathological subjects. In depressive disorders, many studies have shown a decrease of P300 amplitude and an increase of its latency. However, functional significance of the P300 modifications remain unclear. The aim of the study was to assess the influence of suicidal risk and hopelessness on P300 amplitude among 40 depressive inpatients. The results showed significant relationships between P300 amplitude and suicidal risk (r = -0.68, p < 0.001) and with hopelessness (r = -0.76, p < 0.001). From a clinical point of view, P300 amplitude should be considered as a psychophysiological index of suicidal risk in major depressive disorder. [less ▲]

Detailed reference viewed: 28 (1 ULg)
Peer Reviewed
See detailDecomposing efficiency into its managerial and its regulatory components: The case of European railways
Gathon, Henry-Jean ULg; Pestieau, Pierre ULg

in European Journal of Operational Research (1995), 80

Detailed reference viewed: 15 (1 ULg)
Peer Reviewed
See detailAdhesion and costimulatory molecules on human FDC in vitro.
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Advances in Experimental Medicine and Biology (1995), 378

Detailed reference viewed: 10 (0 ULg)
Peer Reviewed
See detailGlucose handling, diabetes and ageing.
Paolisso, G.; Scheen, André ULg; Lefebvre, Pierre ULg

in Hormone Research (1995), 43(1-3), 52-7

The relationship between ageing and glucose homeostasis is still an open debate. In fact, the mechanisms by which glucose metabolism is progressively impaired with increasing age are not completely ... [more ▼]

The relationship between ageing and glucose homeostasis is still an open debate. In fact, the mechanisms by which glucose metabolism is progressively impaired with increasing age are not completely understood. In the present report we have reviewed the possible mechanisms (impaired insulin secretion and action, role of the environmental factors) which may lead to the impairment in glucose handling associated with ageing. We also point out that not all aged subjects are glucose intolerant; in fact, it has been suggested that only those aged subjects who present more than one pathological finding do in fact develop impaired glucose handling. [less ▲]

Detailed reference viewed: 15 (1 ULg)
See detailUltraviolet observations of the Saturnian north aurora and polar haze distribution with the HST-FOC
Gérard, Jean-Claude ULg; Dols, V.; Grodent, Denis ULg et al

in NASA STI/Recon Technical Report N (1995), 96

Near simultaneous observations of the Saturnian H2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the Hubble Space Telescope ... [more ▼]

Near simultaneous observations of the Saturnian H2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the Hubble Space Telescope. The auroral observations cover a complete rotation of the planet and, when co-added, reveal the presence of an auroral emission near 80 deg N with a peak brightness of about 150 kR of total H2 emission. The maximum optical depth of the polar haze layer is found to be located approximately 5 deg equatorward of the auroral emission zone. The haze particles are presumably formed by hydrocarbon aerosols initiated by H2+ auroral production. In this case, the observed haze optical depth requires an efficiency of aerosol formation of about 6 percent, indicating that auroral production of hydrocarbon aerosols is a viable source of high-latitude haze. [less ▲]

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailSuccessful abdominal aortic aneurysm resection in long-term survivors of cardiac transplantation.
Defraigne, Jean-Olivier ULg; SakalihasanN, Natzi ULg; DEMOULIN, Julie ULg et al

in Cardiovascular Surgery (1995), 3(3), 321-4

With the improvement of survival rates following cardiac transplantation, the probability of recipients developing extracardiac disease is increased. Three cases are reported of abdominal aortic aneurysm ... [more ▼]

With the improvement of survival rates following cardiac transplantation, the probability of recipients developing extracardiac disease is increased. Three cases are reported of abdominal aortic aneurysm successfully operated on in cardiac allograft recipients 1 to 4 years after transplantation. Indications for transplantation were valvular, idiopathic and ischaemic cardiomyopathy. Post-transplant hypertension and hyperlipidaemia may have played a role in the rapid growth of the aneurysms. Cardiac function and the incidence of graft atherosclerosis were assessed before surgery by coronary angiography. All three patients were discharged from hospital. Abdominal aortic aneurysm resection may be a safe procedure in cardiac transplant patients. In view of the rapid increase in the size of the aneurysms in transplanted patients, careful screening should be performed during follow-up. [less ▲]

Detailed reference viewed: 13 (2 ULg)
Peer Reviewed
See detailRobert Feulgen Prize Lecture 1995. New approaches to in situ detection of nucleic acids.
Thiry, Marc ULg

in Histochemistry & Cell Biology (1995), 104(2), 81-95

The present paper reviews recent results obtained by different molecular biology-based, immunocytological approaches to the localization and identification of nucleic acids in sections of biological ... [more ▼]

The present paper reviews recent results obtained by different molecular biology-based, immunocytological approaches to the localization and identification of nucleic acids in sections of biological material. Examples of sensitive, high-resolution detection methods for RNA, DNA or specialized DNA regions are presented. Special emphasis is placed on the potential values and limitations of these new methods. [less ▲]

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detail- Establishment of normal and transformed root cultures of Artemisia annua L. for artemisinin production.
Jaziri, M.; Shimomura, K.; Yoshimatsu, K. et al

in Journal of Plant Physiology (1995), 145(1-2), 175-177

Transformed cultures of Artemisia annua L. (Asteraceae) were established by the co-culture method using leaf segments of A. annua and Agrobacterium rhizogenes NCIB 8196 or MAFF 03-01724. The hairy root ... [more ▼]

Transformed cultures of Artemisia annua L. (Asteraceae) were established by the co-culture method using leaf segments of A. annua and Agrobacterium rhizogenes NCIB 8196 or MAFF 03-01724. The hairy root clones thus obtained grew vigorously on hormone-free medium, showing the typical transformed morphology. The genetic transformation of the root was proved by the opine assay. Normal root and shoot cultures were also established. A highly specific and sensitive enzyme-linked immuno-sorbent assay (ELISA) method was used for the detection and semi-quantitative determination of artemisinin and structurally related compounds in these cultures. The presence of artemisinin was confirmed by gas chromatography coupled to mass spectrometry (GC-MS) analysis. The hairy roots cultured in the dark produced no detectable level of artemisinin as shown by the adventitious shoots cultured under light conditions. The ELISA analysis of the green hairy roots cultured in liquid medium under a 16 h light/day photoperiod showed the existence of compound(s) structurally related to artemisinin, though normal and hairy roots cultured in the dark give no detectable levels of immuno-signal. [less ▲]

Detailed reference viewed: 63 (8 ULg)
Full Text
Peer Reviewed
See detailCD4+ T cells determine the ability of spleen cells from F1 hybrid mice to induce neonatal tolerance to alloantigens and autoimmunity in parental mice
Gonzales, M.; Schurmans, Stéphane ULg; Ramos, A. et al

in European Journal of Immunology (1995), 25

Spleen cells from F1 hybrid mice injected into newborn parental mice induce a state of cytolytic unresponsiveness to the corresponding alloantigens. However, these mice develop a transient autoimmune ... [more ▼]

Spleen cells from F1 hybrid mice injected into newborn parental mice induce a state of cytolytic unresponsiveness to the corresponding alloantigens. However, these mice develop a transient autoimmune syndrome characterized by the production of multiple autoantibodies and glomerulonephritis. Previous reports indicated that the depletion of F1 donor T cells, shortly prior the injection into parental mice, does not interfere with any of these events. Here, we have explored whether the continuous absence of T cells in F1 mice influences the ability of their spleen cells to induce neonatal tolerance to alloantigens and the associated autoimmune manifestations. Our results revealed that spleen cells from athymic (BALB/c x C57BL/6) F1 hybrid (CB6F1) nu/nu mice or from euthymic CB6F1 mice depleted from birth of CD4+ T cells, but not of CD8+ T cells, are unable to induce neonatal tolerance to alloantigens and autoimmune manifestations. By contrast, the partial reconstitution of T cells in CB6F1 nu/nu mice, after the neonatal graft of a syngeneic thymus, restored the capacity of spleen cells from these mice to induce tolerance and autoimmunity when injected into newborn BALB/c mice. These results demonstrate that the functional defect of spleen cells from athymic CB6F1 nu/nu mice to induce neonatal tolerance to alloantigens is directly related to the long-term absence of mature CD4+ T cells. Interestingly, a new increase in the titers of anti-DNA Ab was observed when spleen cells from athymic CB6F1 nu/nu mice were injected into adult BALB/c mice that had been tolerized at birth with normal CB6F1 spleen cells. This finding indicates that B cells from CB6F1 nu/nu mice recover their capacity to interact with alloreactive Th2 cells when they are placed into mice having functional CD4+ T cells. These data indicate that the continuous absence of CD4+ T cells causes a reversible functional defect in F1 spleen cells that determines their inability to induce neonatal tolerance and autoimmunity [less ▲]

Detailed reference viewed: 21 (5 ULg)
Full Text
Peer Reviewed
See detailThe quark propagator from the Dyson-Schwinger equations: (I). The chiral solution
Cudell, Jean-René ULg; Gentles, A. J.; Ross, D. A.

in Nuclear Physics B (1995), 440

Detailed reference viewed: 4 (3 ULg)
Full Text
Peer Reviewed
See detailDynamic generalized linear models and repeated measurements
Lindsey, James ULg; Lambert, Philippe ULg

in Journal of Statistical Planning & Inference (1995), 47

The dynamic generalized linear model for non-normal data is extended for use in repeated measurements, when series of observations are available for more than one individual. Examples are given for count ... [more ▼]

The dynamic generalized linear model for non-normal data is extended for use in repeated measurements, when series of observations are available for more than one individual. Examples are given for count and duration data. [less ▲]

Detailed reference viewed: 40 (2 ULg)
See detailLes ossements animaux de la villa gallo-romaine de Mageroy à Habay-la-Vieille
Mees, G; Gabriel, Annick ULg

in Arc-Hab., Bulletin trimestriel (1995), (9), 2-20

Detailed reference viewed: 4 (0 ULg)
See detailUn autre regard sur les atlas de France et de Belgique.
Vansteenwegen, Christian; Dufrêne, Marc ULg; Lebrun, Philippe

in AVES (1995), 31

Detailed reference viewed: 1 (1 ULg)
Peer Reviewed
See detailEn Belgique, diverses modalités de pâturage pour des taurillons avant finition à l'auge
Dufrasne, Isabelle ULg; Gielen, Marc ULg; Limbourg, Pierre et al

in Fourrages (1995), 141

Detailed reference viewed: 15 (0 ULg)
See detailTrente cinq années de programmes d'histoire dans l'enseignement secondaire francophone
Jadoulle, Jean-Louis ULg

in Histoire et Enseignement : Bulletin (1995), 45e année(n°3), 1-6

Detailed reference viewed: 14 (0 ULg)
Peer Reviewed
See detailLa clé de saint Hubert
George, Philippe ULg; Weber, Georges ULg; martinot lucien

in Feuillets de la Cathédrale de Liège (1995)

Detailed reference viewed: 7 (0 ULg)
Peer Reviewed
See detailLe risque familial de l'anévrisme de l'aorte abdominale et ses conséquences pour l'organisation d'un dépistage sélectif
Limet, Raymond ULg

in Journal des Maladies Vasculaires (1995), 20(4), 285-7

Aneurysm of the abdominal aorta (AAA) is multifactorial disease related to acquired factors (arteriosclerosis) and genetic factors (collagen anomalies) with, in some cases, a familial component. The ... [more ▼]

Aneurysm of the abdominal aorta (AAA) is multifactorial disease related to acquired factors (arteriosclerosis) and genetic factors (collagen anomalies) with, in some cases, a familial component. The incidence of familial AAA was evaluated in 324 patients in 313 families who underwent surgery for AAA. A family survey was used to determine whether members of the operated patients had AAA or had died due to ruptured aneurysms. There were 276 cases (including 12 females) with sporadic AAA and 81 cases (including 5 females) who were members of families with at least one other member having AAA. Comparison between sporadic AAA (SAAA) and familial AAA (FAAA) demonstrated the following differences: 1) diagnosis was made earlier in FAAA (p < 0.05) than in SAAA (64.1 versus 66 years of age respectively), 2) patients with FAAA were younger at the time of rupture (65.4 versus 75.1 years, p < 0.001), 3) the incidence of rupture was greater in FAAA than in SAAA (32.4% versus 8.7% p < 0.001), and finally 4) the relative risk of developing AAA was 18 times greater in members of a family with AAA than in the reference population. Early screening with ultrasonic examinations in at least patient's brother's over 50 years would not be an unjustified expense. The frequency of later examinations would depend on the size of the aorta initially observed. If FAAA is evidenced, under normal conditions, corrective surgery should be proposed earlier than for sporadic AAA. [less ▲]

Detailed reference viewed: 29 (1 ULg)
See detailprésentation de : Abbé Lhomond, De viris (les grands hommes de Rome), Latin/français, traduit et présenté par J. Gaillard, Paris, 1995
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (1995), 99

Detailed reference viewed: 24 (0 ULg)
Peer Reviewed
See detailFear reactions of domestic sheep confronted with either a human or a human-like model
Bouissou, Marie-France; Vandenheede, Marc ULg

in Behavioural Processes (1995), 34

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailNausea and vomiting in fractionated radiotherapy: a prospective on-demand trial of tropisetron rescue for non-responders to metoclopramide.
Miralbell, R; COUCKE, Philippe ULg; Behrouz, F et al

in European Journal of Cancer Prevention (1995)

A prospective trial was performed to better assess the risk of nausea and vomiting and the rescue value of tropisetron (TRO), a 5HT3 receptor antagonist, in 88 patients undergoing fractionated ... [more ▼]

A prospective trial was performed to better assess the risk of nausea and vomiting and the rescue value of tropisetron (TRO), a 5HT3 receptor antagonist, in 88 patients undergoing fractionated radiotherapy to the abdomen or to large supradiaphragmatic fields and failing a first anti-emetic trial with metoclopramide (MET). Nausea was graded 0 (absent), 1 (mild), 2 (moderate) and 3 (severe). Nausea requiring anti-emetics (L grade 2) was present in 64% of the patients. MET was able to control nausea (I grade 1) in 26 of 58 patients (45%) who developed 1 grade 2 nausea during radiation treatment (2 patients vomiting without nausea included). 34 patients required TRO, and 31 experienced immediate relief. However, nausea (1 grade 2) recurred in 7 patients from 1 to 3 weeks after starting, TRO. Sex, age, field type and field size (cm*) did not influence the incidence and severity of nausea and vomiting. Only 24188 patients vomited after starting radiotherapy. MET helped to eliminate emesis in one third of these patients. TRO helped to control vomiting in 73% of the salvaged patients. Constipation was observed in 8 patients on TRO and was a reason to stop the medication in 4 cases. [less ▲]

Detailed reference viewed: 22 (4 ULg)
Full Text
Peer Reviewed
See detailThe Cenozoic evolution of the strontium and carbon cycles: Relative importance of continental erosion and mantle exchanges
Godderis, Y.; François, Louis ULg

in Chemical Geology (1995), 126(2), 169-190

The past variations of the seawater Sr-87/Sr-86 isotopic ratio are related to changes in the relative contribution of the mantle Sr input to the ocean and the Sr supply from continental weathering ... [more ▼]

The past variations of the seawater Sr-87/Sr-86 isotopic ratio are related to changes in the relative contribution of the mantle Sr input to the ocean and the Sr supply from continental weathering. Recently, it has been postulated that the Cenozoic increase in the seawater Sr-87/Sr-86 isotopic ratio was associated with the uplift of the Himalayan and Andean mountains at that time. These orogenies may have changed the Sr isotopic ratio of the continental rocks undergoing weathering (as a result of extensive metamorphism), increased the river flux of Sr through enhanced weathering in these regions and possibly caused the global climatic cooling trend of the Cenozoic. A model of the major geochemical cycles coupled to an energy balance climate model is used to explore the possible causes of the Mesozoic-Cenozoic fluctuations in the seawater Sr-87/Sr-86 isotopic ratio. The contribution of the mantle exchanges at mid-ocean ridges, of the recycling of seafloor carbonates through plate margin volcanism and of the alteration of seafloor basalts to the fluctuations of the seawater Sr-87/Sr-86 isotopic ratio are studied. Finally, this model tentatively describes the impact of the Himalayan orogeny on the geochemical cycles of Sr and C. Some possible effects of the extensive metamorphism associated with the India-Asia collision and of the Himalayan uplift are modelled. The model reproduces the Cenozoic increase of the seawater Sr-87/Sr-86 isotopic ratio. However, the impact of the Himalayan orogeny on the C cycle appears to be limited and insufficient to generate the global climatic cooling of the Cenozoic. Rather, in the model, the Cenozoic cooling is mostly due to the reduction of the CO2 emission from mid-ocean ridge volcanism and to changes in the chemical weathering rates in the rest of the world excluding the Himalayas. [less ▲]

Detailed reference viewed: 30 (1 ULg)
Peer Reviewed
See detailEffects of an enriched environment on subsequent fear reactions of lambs and their mothers.
Vandenheede, Marc ULg; Bouissou, Marie-France

in Applied Animal Behaviour Science (1995), 44

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailThiamine Homeostasis in Neuroblastoma Cells
Bettendorff, Lucien ULg

in Neurochemistry International (1995), 26(3), 295-302

We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other ... [more ▼]

We recently showed that thiamine uptake by neuroblastoma cells is mediated by two saturable transport system: the first with high affinity for thiamine (Km = 35 nM) is blocked by veratridine; the other, with low affinity is blocked by Ca2+. The driving force for thiamine uptake is its phosphorylation to thiamine diphosphate (TDP) by thiamine pyrophosphokinase and subsequent binding of this cofactor to apoenzymes. Our results suggest that cells of neuronal origin possess mechanisms regulating the intracellular concentration of thiamine. At low external thiamine, the vitamin is taken up by a high-affinity transporter and pyrophosphorylated in thiamine diphosphate (TDP): this is the TDP pool of slow turnover. An intraover extracellular concentration gradient of free thiamine is observed at low external concentration of the vitamin. At higher external thiamine concentration, TDP accumulation is limited by the binding capacity to the apoenzymes and unbound TDP (i.e. a small pool of fast turnover) is quickly hydrolyzed. Thiamine is slowly released by the cells by at least two different mechanisms. The first, accounting for a maximum of 50% of total thiamine release, is stimulated by external thiamine and is blocked by veratridine, suggesting that it is a self-exchange mechanism catalyzed by the high affinity thiamine transporter. The remaining thiamine efflux is neither sensitive to veratridine nor to Ca2+ and its mechanism is unknown. About 25% of intracellular thiamine is not released, even after treatment of the cells with digitonin, thus maintaining an apparent gradient. This suggests a binding or sequestration in intracellular compartments.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailRegime et tactique alimentaires de la loutre (Lutra lutra) en France: synthèse.
Libois, Roland ULg

in Cahiers d'Ethologie (1995), 15(2-3-4), 251-274

More than 1500 otter spraint samples have been collected in different aquatic habitats throughout the present geographic range of the otter in France. Prey remains were identified, the relative occurrence ... [more ▼]

More than 1500 otter spraint samples have been collected in different aquatic habitats throughout the present geographic range of the otter in France. Prey remains were identified, the relative occurrence and abundance of each species was assessed and the biomass of each individual prey estimated. When available, data about the fish communities (size frequency- distributions, relative abundance) were compared with the diet of the mustelid. The main conclusions of the study are as follows: 1. The otter is mainly piscivorous but some other aquatic (crayfish) or semiaquatic preys (frogs, Natrix-snakes, some birds and mammals) are of major dietary importance in oligotrophic habitats. 2. The composition of the diet is determined by the local fish resources. The otter is an opportunistic predator, its diet varying greatly from one place to another. The diet can also change depending upon the season or upon some special circumstances such as frog or fish reproduction or strong prey-community changes. 3. Small fish are dominant in the diet. No size selection has been evidenced at least in the eel and in the cyprinid fishes. As far as the trout is concerned, it seems that the otter consumes preferably medium sized individuals. 4. The proportion of some prey species is lower in the diet than in the habitat. These are the more pelagic (bleak, sander, breams), rheophilic (dace, chub) or group-living species (minnow, roach). Bottom- (bullhead, eel, tench, gudgeon, barbel) or plant-living (rudd, pike) species are more frequent. [less ▲]

Detailed reference viewed: 75 (8 ULg)
Full Text
Peer Reviewed
See detailProtective Effect of Various Antagonists of Inflammatory Mediators against Paraoxon-Induced Pulmonary Edema in the Rabbit
Delaunois, Annie ULg; Gustin, Pascal ULg; Vargas, M. et al

in Toxicology and Applied Pharmacology (1995), 132(2), 343-345

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The ... [more ▼]

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The edema induced by paraoxon has been previously related to a chain reaction mediated by acetylcholine. Lungs were ventilated and blood-free perfused with a constant flow. Arterial and venous pressures and lung weight were continuously recorded. Endothelial permeability was evaluated by measuring the capillary filtration coefficient (Kf,c). Paraoxon (4 x 10(-4) M) was injected in the perfusion circuit, in lungs with or without pretreatment with atropine, ketanserin, clonidine, morphine, indomethacin, and terfenadine plus cimetidine. Paraoxon induced a time-dependent increase in the Kf,c, a maximal effect being recorded 60 min after the injection. All the antagonists used as pretreatment significantly reduced the maximal effect recorded after paraoxon. These results show that muscarinic receptor antagonists, inhibitors of neuropeptides release, cyclooxygenase inhibitors, and 5-hydroxytryptamine and histamine receptor antagonists can protect the lung against the edema induced by paraoxon. This protective effect is due to inhibition of the chain reaction triggered by acetylcholine. [less ▲]

Detailed reference viewed: 6 (1 ULg)
Peer Reviewed
See detailGrowth hormone response to apomorphine in panic disorder: comparison with major depression and normal controls.
Pichot, W.; Hansenne, Michel ULg; Gonzalez Moreno, A. et al

in European Archives of Psychiatry & Clinical Neuroscience (1995), 245(6), 306-8

Several lines of evidence suggest that dopamine might be involved in anxiety states. In the present study we assessed the growth hormone (GH) response to 0.5 mg apomorphine (a dopaminergic agonist) in 10 ... [more ▼]

Several lines of evidence suggest that dopamine might be involved in anxiety states. In the present study we assessed the growth hormone (GH) response to 0.5 mg apomorphine (a dopaminergic agonist) in 10 male drug-free inpatients meeting Research Diagnostic Criteria for panic disorder who were compared with 10 male major depressive inpatients and 10 male normal controls. The three groups differed significantly in the GH peak response (mean +/- SD): 27.8 +/- 12.5 ng/ml in panics, 5.4 +/- 4.0 ng/ml in major depressives, and 25.8 +/- 11.3 ng/ml in normal controls (F(2,27) = 15.3; P = 0.00003). Although there were significant differences between panics and major depressives (P = 0.00004), and between major depressives and controls (P = 0.00004), panics did not significantly differ from controls. These results do not support the hypothesis of an overlap between panic and affective disorders, and suggest that the hypothalamo-GH-somatomedin axis could be intact in panic disorder. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Peer Reviewed
See detailVariational Calculationof the Dynamic Third-Order Susceptibility of Water
Gabryl, Jean-René; Barbier, Christian ULg; Lemaire, Philippe et al

in Journal of Molecular Structure : Theochem (1995), 357

Detailed reference viewed: 19 (4 ULg)
Peer Reviewed
See detailHeterotransplantation of Primary and Established Human Tumour Cells in Nude Mice
Noël, Agnès ULg; Borcy, V.; Bracke, M. et al

in Anticancer Research (1995), 15(1, Jan-Feb), 1-7

Previous successful transplantations of human tumour cells into athymic nude mice have been described when cells were injected with a reconstituted basement membrane (matrigel). We have compared the ... [more ▼]

Previous successful transplantations of human tumour cells into athymic nude mice have been described when cells were injected with a reconstituted basement membrane (matrigel). We have compared the development and the histology of tumours following injection with matrigel or with culture medium of a panel of tumour cells exhibiting different degrees of tumorigenicity. Two cell lines (MCF7 and MCF7/6) required matrigel in order to form tumours. When inoculated with matrigel, all the other cell lines tested [MCF7 gpt, MCF7ras, MCF7(AZ), MCF7(AZ)TD5, MDA-MB 231, HT1080] showed increased tumour take and reduced latency period. Human primary tumours (melanoma, breast and colon cancers) were transplanted successfully into nude mice, in the presence of matrigel. Breast primary tumours or cell lines gave rise to poorly differentiated carcinomas. The other tumours presented histopathological patterns typical of differentiated human cancers. [less ▲]

Detailed reference viewed: 27 (1 ULg)
Full Text
Peer Reviewed
See detailMeasuring productive performance in the non-life insurance industry: the case of French and Belgian markets
Fecher-Bourgeois, Fabienne ULg; Pestieau, Pierre ULg; Perelman, Sergio ULg et al

in Tijdschrift voor Economie en Management (1995), (40), 47-69

Detailed reference viewed: 27 (11 ULg)
Peer Reviewed
See detail24-hour glucose profiles during continuous or oscillatory insulin infusion. Demonstration of the functional significance of ultradian insulin oscillations.
Sturis, J.; Scheen, André ULg; Leproult, R. et al

in Journal of Clinical Investigation (1995), 95(4), 1464-71

Under basal and stimulated conditions, normal insulin secretion oscillates with periods in the ultradian 100-150-min range. To test the hypothesis that oscillatory insulin delivery is more efficient in ... [more ▼]

Under basal and stimulated conditions, normal insulin secretion oscillates with periods in the ultradian 100-150-min range. To test the hypothesis that oscillatory insulin delivery is more efficient in reducing blood glucose levels than continuous administration, nine normal young men were each studied on two occasions during a 28-h period including a period of polygraphically recorded sleep. Endogenous insulin secretion was suppressed by somatostatin, a constant intravenous glucose infusion was administered, and exogenous insulin was infused either at a constant rate or in a sinusoidal pattern with a period of 120 min. The mean glucose level over the 28-h period was 0.72 +/- 0.31 mmol/liter lower when insulin was infused in an oscillatory pattern than when the rate of infusion was constant (P < 0.05). The greater hypoglycemic effect of oscillatory versus constant infusion was particularly marked during the daytime, with the difference averaging 1.04 +/- 0.38 mmol/liter (P < 0.03). Serum insulin levels tended to be lower during oscillatory than constant infusion, although the same amount of exogenous insulin was administered under both conditions. Ultradian insulin oscillations appear to promote more efficient glucose utilization. [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailAccroissement des exportations agricoles et sécurité alimentaire au Viêt-nam
Lebailly, Philippe ULg; Burny, Philippe ULg

in Economies et sociétés. Série Développement agro-alimentaire, A.G. (1995), 22(3-4), 361-371

La rénovation des politiques et des méthodes d'action à l'égard de l'agriculture a permis au Viêt-nam de conforter sa position de troisième exportateur mondial de riz. Néanmoins la situation semble moins ... [more ▼]

La rénovation des politiques et des méthodes d'action à l'égard de l'agriculture a permis au Viêt-nam de conforter sa position de troisième exportateur mondial de riz. Néanmoins la situation semble moins favorable qu'il n'y paraît. Le marché international du riz est caractérisé par des prix bas et par une forte concurrence entre pays exportateurs. En outre, le marché est réduit et instable. Il s'ensuit que le Viêt-nam, proche de l'autosuffisance, peut tantôt être importateur tantôt exportateur de riz selon les performances enregistrées par les riziculteurs. Cet article analyse les perspectives qui sont actuellement offertes au Viêt-nam en matière de sécurité alimentaire en relation avec l'adoption d'une politique agricole qui encourage l'accroissement des exportations de riz. [less ▲]

Detailed reference viewed: 66 (19 ULg)
Full Text
Peer Reviewed
See detailVaricella-zoster virus gene regulation
Piette, Jacques ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Neurology (1995), 45(12, suppl. 8), 23-27

The varicella-zoster virus genome contains 71 open reading frames (ORFs), five of which (ORF62, ORF4, ORF63, ORF61, and ORF10) encode regulatory proteins. ORF62 codes for the major immediate early protein ... [more ▼]

The varicella-zoster virus genome contains 71 open reading frames (ORFs), five of which (ORF62, ORF4, ORF63, ORF61, and ORF10) encode regulatory proteins. ORF62 codes for the major immediate early protein of the virus exhibiting DNA-binding and regulatory functions. This protein, localized in the cell nucleus, is a functional homologue to ICP4 of herpes simplex virus type 1 (HSV-1). It trans-activates several varicella-zoster virus promoters of the various gene classes and autoregulates its own expression. ORF4 protein activates gene promoters provided they have basal activities, but it is not a functional homologue of HSV-1 ICP27. Gene regulation activity appears to be linked to its cysteine-rich C-terminal region. ORF63 codes for an immediate early protein mainly located in the cell nucleus. The regulatory functions it performs are still unclear. ORF61 protein is the functional homologue of HSV-1 ICPO. Its N-terminal region exhibits a RING domain responsible for trans-activating and trans-repressing activities. ORF10 protein exhibits similarities with HSV-1 VP16 and activates the ORF62 promoter. [less ▲]

Detailed reference viewed: 13 (2 ULg)