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See detailLe Pr J.-M. Krzesinski (CHU sart Tilman, ULg) a sélectionné pour vous...
Krzesinski, Jean-Marie ULg

in Tempo Médical (2002), 240

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See detailMigraines et vertiges, une relation à vous faire tourner la tête
FUMAL, Arnaud ULg; Schoenen, Jean ULg

in Migraine Contact (2002), 2

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See detailUse of specific bioluminescent cell lines for the detection of steroid hormone (ant)agonists in meat producing animals
Willemsen, Philippe; Scippo, Marie-Louise ULg; Maghuin-Rogister, Guy ULg et al

in Analytica Chimica Acta (2002), 473(1-2), 119-126

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of ... [more ▼]

We present stable transformed human mammary cell lines displaying highly inducible steroid receptor-mediated luciferase reporter gene expression. The utilization of a cell-based assay for detection of steroid agonists and antagonists down to 0.3 ng g(-1) is described and its application to the analysis of bovine samples is discussed. In particular, the use of the assays to detect illegal progesterone or androgen treatment has to take into account the presence of natural endogenous hormones. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailOver Kathrin Kötz, Die Prosa Paul van Ostaijens
Spinoy, Erik ULg

in Nachbarsprache Niederländisch (2002), 17(1-2), 122-125

This is a review of a study by Katrhin Kötz on Paul van Ostaijen's literary ('grotesque') prose and its German influences.

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See detailModulation of neuronal survival and excitability by an astroglia-derived factor.
HANS, Grégory ULg; Moonen, Gustave ULg; Rigo, Jean-Michel

in Journal of physiology, Paris (2002), 96(3-4), 323-8

We summarize here currently available data related to an astroglia-secreted factor that induces neuronal apoptosis and behaves as an inhibitor of ionotropic inhibitory GABA(A) and glycine receptors.

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See detailPourquoi la Finlande a-t-elle tant de jeunes bons lecteurs ?
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 9-10

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See detailRecommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma
Holgate, ST; Bousquet, J; Chung, KF et al

in International Journal of Pharmaceutical Medicine (2002), 16

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See detailStratégies de prévention des avortements provoqués par les herpèsvirus et les pestivirus de ruminants
Thiry, Etienne ULg

in Annales de Médecine Vétérinaire (2002), 146(3, JUN-JUL), 161

Bovine herpesviruses 1 and 4 (BoHV-1 and BoHV-4) and caprine herpesvirus (CpHV-1) are responsible of abortion. Abortions caused by BoHV-1 happen during outbreaks of infectious bovine rhinotracheitis ... [more ▼]

Bovine herpesviruses 1 and 4 (BoHV-1 and BoHV-4) and caprine herpesvirus (CpHV-1) are responsible of abortion. Abortions caused by BoHV-1 happen during outbreaks of infectious bovine rhinotracheitis whereas BoHV-4 is associated with abortion but is not a very high risk factor. CpHV-1 infection is not yet identified in Belgium and in France. Bovine and ovine pestiviruses, bovine viral diarrhea and Border disease viruses, respectively, provoke abortions mainly during the first half of gestation. At the herd level, the prevention of abortion caused by these viruses can be achieved by the control of virus circulation with the help of vaccination or the elimination of persistently infected animals. At the individual level, immunisation with inactivated vaccines induces a high humoral response with high levels of neutralising antibodies, able to prevent the viremia and foetus infection. [less ▲]

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See detailLa traducción, otra de las plenitudes de Borges
Willson, Patricia ULg

in Variaciones Borges (2002), (14), 103-112

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See detailInsecticide resistance enhances male reproductive success in a beetle
Arnaud, Ludovic; Haubruge, Eric ULg

in Evolution (2002), 56(12), 2435-2444

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See detailLes acteurs et les enjeux au coeur de l'évaluation
Vandoorne, Chantal ULg

in Education santé (2002), 173(173), 9-11

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See detailEuro- en zijn concurrenten
Meesters, Gert ULg

in Leuvense Bijdragen (2002), 91(1-2), 79-96

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the ... [more ▼]

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the European currency. The article especially deals with the relationship between word formation with euro- and three other means of expressing more or less the same meaning: word formation with EG- (abbreviation of Europese Gemeenschap, i.e. European Union) as a first component, word formation with Europa- (Europe) as a first component and word groups with the adjective Europees (European). This relationship is explored in two comparative studies. First the token frequency in a corpus is investigated. It turns out that euro- is more frequent than Europa-, but less frequent than EG- and Europees. In a second comparison the semantic-functional domains of the four alternatives are considered in detail. Euro- apparently can be used as an alternative for Europees and EG- when the referents are related to the European Union, and as an alternative for Europees in ‘bilateral’ adjectives such als Euro-Russisch. It also has a few domains of its own: commercial proper names and words expressing an attitude towards the European Union. An additional analysis of individual words and word groups with different alternatives from this paradigm as a first component but the same second component reveals that even in individual cases of competition with other alternatives, the variant with euro- is sometimes the most frequent or the institutionalized form. It is concluded that within the linguistic potential of naming referents that relate to Europe, euro- has its own specific value as a productive means of word formation. [less ▲]

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See detailAssesment of the situation, three years later, on 'the Belgian Dioxin Crisis'. Probable impact on the health of the Belgian population
Focant, Jean-François ULg; Pirard, Catherine ULg; Douny, Caroline ULg et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 321-327

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on ... [more ▼]

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on public health. Currently, it does not really exist any exhaustive epidemiological study. Various scientific studies actually report somewhat conflicting results. As an example, concerning the population living in Wallonia, recorded dioxin levels are not higher than background levels reported for other industrialized countries, despite the 1999 "dioxin crisis". Conversely, based on levels measured in foodstuffs collected by the end of the crisis period, the dioxin body burden of potential consumers would have increased in the range of 40 to 75 %. The real impact of this crisis on consumers' health could thus only be estimated through well structured epidemiological campaigns. [less ▲]

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See detailPhylogéographie mitochondriale du mulot sylvestre (Apodemus sylvaticus) dans la région paléarctique occidentale
Michaux, Johan ULg; Magnanou, Elodie; Nieberding, Caroline et al

in Biosystema, Systématique et biogéographie (2002), 20

We have sequenced 965 base pairs of the mitochondrial DNA cytochrome b from 102 woodmice (Apodemus sylvaticus) samples collected from 40 European localities. The aims of the study were to answer the ... [more ▼]

We have sequenced 965 base pairs of the mitochondrial DNA cytochrome b from 102 woodmice (Apodemus sylvaticus) samples collected from 40 European localities. The aims of the study were to answer the following questions: i) Did the Mediterranean peninsulas play a role as a refuge for small mammals? ii) Is the genetic variability of a small mammal like A. sylvaticus higher in the Mediterranean regions as compared with northern Europe? iii)Is it possible to find patterns of postglacial colonisation of Europe other than those presently recognised ? Sequence data were analysed using Distance and Maximum Parsimony phylogenetic reconstruction methods. A minimum spanning network was also calculated. Population genetic structure was determined by analysis of molecular variance (AMOVA). A "mismatch distribution" analysis was also performed to estimate the patterns of expansion. The results provide a clear picture of the impact of Quaternary glaciations on the genetic and geographic structure of the woodmouse. Analyses indicate a higher genetic variability for the woodmouse in the Mediterranean peninsulas as compared to northern Europe and the role of these peninsulas as refuge regions for small mammals. A new pattern of postglacial colonisation is also proposed where the Iberian and southern France refuge populations colonised almost all the European regions. The Sicilian population appears to be highly differentiated and highly variable. This result emphasises the importance of this island as a "hot spot" for the intraspecific genetic diversity of the woodmouse. Finally, populations of this species in North Africa originated from south-western Europe and are probably the result of a recent anthropogenic introduction. [less ▲]

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See detailQuantitative and qualitative estimation of bacteria in foodstuffs by genetic amplification
China, Bernard; Ghafir, Yasmine; Daube, Georges ULg

in Annales de Médecine Vétérinaire (2002), 146(2, APR-MAY),

Food quality is a major concern of our modern society. The sudden awareness that food is not sterile underlines the need of a rigorous microbiological analysis of foodstuffs. The techniques developed ... [more ▼]

Food quality is a major concern of our modern society. The sudden awareness that food is not sterile underlines the need of a rigorous microbiological analysis of foodstuffs. The techniques developed until now require the growth of the microorganism on a selective medium allowing to differentiate it from other bacteria. This procedure could be long and difficult for the analysis. To improve these classical methods, molecular biology techniques based on the specific amplification of a DNA sequence are in development. Moreover, the apparition of real time PCR allows new future prospects since it allows to quantify the number of bacteria present in a sample. This quantitative aspect is very important in food microbiology. In this way, the molecular biology tools should allow to develop fast, sensitive, specific and quantitative diagnosis tests to confirm the results obtained by classical methods but also to allow the diagnosis of fastidious bacteria. [less ▲]

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See detailA performance study of RSVP with proposed extensions
Mathy, Laurent ULg; Hutchison, D.; Schmid, S. et al

in Computer Communications (2002), 25(18), 1782--1798

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See detailMorphology, displacement and slip rates along the North Antolian Fault (Turkey)
Hubert, Aurelia ULg; Armijo, R.; Meyer, B. et al

in Journal of Geophysical Research (2002), 107(10.1029/2001JB000393),

Geological and geomorphological offsets at different scales are used to constrain the localization of deformation, total displacement, and slip rates over various timescales along the central and eastern ... [more ▼]

Geological and geomorphological offsets at different scales are used to constrain the localization of deformation, total displacement, and slip rates over various timescales along the central and eastern North Anatolian Fault (NAF) in Turkey. The NAF total displacement is reevaluated using large rivers valleys (80 ± 15 km) and structural markers (Pontide Suture, 85 ± 25 km; Tosya-Vezirko ̈pru ̈ basins, 80 ± 10 km). These suggest a Neogene slip rate of 6.5 mm/yr over 13 Myr. The river network morphology shows offsets at a range of scales (20 m to 14 km) across the main fault trace and is also used to estimate the degree to which deformation is localized. At a smaller scale the morphology associated with small rivers is offset by 200 m along the NAF. The age of these features can be correlated with the Holocene deglaciation and a slip rate of 18 ± 3.5 mm/yr is determined. This is consistent with a rate of 18 ± 5 mm/yr deduced independently from the 14C dating of stream terrace offsets. Over the short term, GPS data gives a similar rate of 22 ± 3 mm/yr. All our results tend to show that most of the deformation between the Anatolian and Eurasian lithospheric plates has been accommodated along, or very close to, the active trace of the NAF. The difference between the Neogene and the Holocene slip rate may be due to the recent establishment of the current plate geometry after the creation of the NAF. INDEX TERMS: 8107 Tectonophysics: Continental neotectonics; 8158 Tectonophysics: Plate motions—present and recent (3040); 7230 Seismology: Seismicity and seismotectonics; KEYWORDS: North Anatolian Fault, slip rate, total offset, strain localization [less ▲]

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See detailCaractérisation de la résistance au Sénégal d'Helicoverpa armigera Hübner (Lépidoptère, Noctuidae) par bioessai et méthodes moléculaires
Moreira, Christine; Schiffers, Bruno ULg; Haubruge, Eric ULg

in Parasitica (2002), 58(2-3-4), 89-98

Un vial-test de détection de la résistance à la cyperméthrine d'Helicoverpa armigera a été vulgarisé (Programme PR-PRAO) en Afrique de l'Ouest (flacon en verre imprégné). Cette étude montre qu'à des ... [more ▼]

Un vial-test de détection de la résistance à la cyperméthrine d'Helicoverpa armigera a été vulgarisé (Programme PR-PRAO) en Afrique de l'Ouest (flacon en verre imprégné). Cette étude montre qu'à des températures de 30°C et 54°C, 4 pyréthrinoïdes et 2 organophosphorés se dégradent rapidement dans les flacons en verre. Un "kit" est présenté sous forme d'un papier filtre traité enveloppé dans une feuille d'aluminium. Il possède une bien meilleure stabilité au stockage (sur 50 jours). Des tests moléculaires, réalisés sur une souche d'H. armigera issue du Sénégal, révèlent deux mutations (la sérine remplacée par l'acide glutamique et l'acide aspartique par la valine) au niveau du gène codant pour le canal sodium voltage dépendant, cible principale des pyréthrinoïdes. [less ▲]

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See detailRumen Escape Of Methionine And Lysine Administered Intraruminally To Growing Double-Muscled Belgian Blue Bulls
Froidmont, Eric; Rondia, Pierre; Thewis, André ULg et al

in Reproduction Nutrition Development (2002), 42(6), 537-544

In many dietary conditions, methionine (Met) and lysine (Lys) are the most limiting amino acids (AA) for ruminants. The AA protected from ruminal fermentation are not commercially available, with the ... [more ▼]

In many dietary conditions, methionine (Met) and lysine (Lys) are the most limiting amino acids (AA) for ruminants. The AA protected from ruminal fermentation are not commercially available, with the exception of Met which is not always economical, especially for meat production. This study measured ruminal escape of free Met and Lys supplemented intraruminally to fast growing bulls. Six double-muscled Belgian Blue bulls, fed a high concentrate diet and fitted with a rumen cannula, received free Met (40 g.d–1) and free Lys (60 g.d–1), individually or simultaneously, in a duplicated Latin square design. The mean ruminal escape of Met and Lys reached 37 and 45% respectively, and did not differ if administered separately or together. Plasma Lys and Met concentrations were increased by 504 and 126%, respectively. Substantial proportions of free AA escaped ruminal fermentation and were available for absorption from the small intestine when they were administered at physiologically high levels. [less ▲]

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See detailLa mémoire des morts à Stavelot-Malmedy. Des origines au XIIe siècle
George, Philippe ULg

in Malmedy Folklore (2002)

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See detailGeneralized Fourier equations and thermoconvective instabilities
Dauby, Pierre ULg; Nelis, M.; Lebon, Georgy ULg

in Revista Mexicana De Fisica (2002), 48(Suppl. 1), 57-62

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See detailSpectral and crystallographic study of pyridinic analogues of nimesulide : determination of the active form of methanesulfonamides as COX-2 selective inhibitors
Julémont, F.; de Leval, X.; Michaux, C. et al

in Journal of Medicinal Chemistry (2002), 45

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See detailEntre Italie et Pays-Bas méridionaux. Le « Libro de memoria » de la famille Cassina. 1576-1650.
Moreno, Paola ULg

in Studi e Problemi di Critica Testuale (2002)

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See detailComputer simulation of liquid semiconductors
Bichara, C.; Gaspard, Jean-Pierre ULg; Raty, Jean-Yves ULg

in Journal of Non-Crystalline Solids (2002), 312

We discuss two examples of computer simulation of liquid semiconductors by two different techniques. Both examples are concerned with the relationship between thermodynamic properties and the atomic ... [more ▼]

We discuss two examples of computer simulation of liquid semiconductors by two different techniques. Both examples are concerned with the relationship between thermodynamic properties and the atomic structure in the liquid state. By means of ab initio molecular dynamics we analyze the atomic structure of liquid Ge15Te85 eutectic alloys. We show that the changes observed in the experimental total structure factor S(q) are located in the GeTe partial structure factor, the TeTe partial structure factor remaining essentially unaltered. Using a semi-empirical tight binding approach, coupled with Gibbs ensemble and constant pressure Monte Carlo calculations, we can calculate the liquid vapor equilibrium of selenium. We obtain a liquid-vapor equilibrium curve and a critical point in the correct range of magnitude and an atomic structure of the liquid phase in good agreement with the experimental data. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailCréation d'un site Internet d'Evidence-Based Medicine.
Delvenne, Catherine ULg; Pasleau, Françoise ULg

in Médi-Sphère (2002), (67), 41-43

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See detailVegetative and generative behaviour of Strawberry (Fragaria x ananassa Duch.) plants raised from in vitro regeneration of axillary or stipular buds
Jemmali, Ahmed; Elloumi, Nedra; Kevers, Claire ULg

in Acta Botanica Gallica : Bulletin de la Société Botanique de France (2002), 149(4), 395-404

In vitro regeneration of strawberry (Fragaria x ananassa Duch.) plants from adventitious stipular buds allowed us to obtain a new clone differing from the axillary originated clone by its vegetative and ... [more ▼]

In vitro regeneration of strawberry (Fragaria x ananassa Duch.) plants from adventitious stipular buds allowed us to obtain a new clone differing from the axillary originated clone by its vegetative and reproductive behavior. Besides of its clear and rounded leaves, this clone is characterized by a slower plastochronal rythm corresponding to the production of a greater number of axillary shoots (runners). Furthermore, its flowers have shorter receptacle that does not overstep stamens. At the contrary, receptacle of the axillary clone largely overstep stamens and then, they are not well pollinated and resulted in malformed fruits especially in cold season or in absence of pollen vectors. [less ▲]

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See detailShort- and long-term advantages of an alternative ontogenetic pathway
Denoël, Mathieu ULg; Hervant, F.; Schabetsberger, R. et al

in Biological Journal of the Linnean Society (2002), 77(1), 105-112

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body ... [more ▼]

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body condition between paedomorphic and metamorphic Alpine newts (Triturus alpestris, Caudata, Amphibia) in four populations. Because we found a strong correlation between fat reserves and body condition, we used this last parameter as an indicator of long-term gains. In all studied sites, paedomorphic females showed higher body condition than metamorphic ones. Paedomorphic males were also at advantage in two populations. Paedomorphs exhibited higher energy intakes than metamorphs in two populations and similar gains in two others. Our results support unifying theories that predict the occurrence of facultative paedomorphosis in varied habitats as paedomorphs exhibited better energy balance than metamorphs. This work shows the need for considering integrative parameters such as body condition in the comparative study of performances when studying developmental heterochronies. (C) 2002 The Linnean Society of London, Biological Journal of the Linnean Society, 2002, 77, 105-112. [less ▲]

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See detailUse of X-ray microtomography to follow the convective heat drying of wastewater sludges
Léonard, Angélique ULg; Blacher, Silvia ULg; Marchot, Pierre ULg et al

in Drying Technology (2002), 20(4-5), 1053-1069

X-ray microtomography is proposed as a new tool to investigate the evolution of size, shape and texture of soft materials during a drying operation. This study is focused on the drying of mechanically ... [more ▼]

X-ray microtomography is proposed as a new tool to investigate the evolution of size, shape and texture of soft materials during a drying operation. This study is focused on the drying of mechanically dewatered sludges from a secondary wastewater treatment. The shrinkage phenomenon is shown to play a crucial role in the control of the drying process. The shrinkage curves are determined by analysing the shape and size of cross sectional microtomographic images of sludge extrudates at different levels of drying. The observation of drying and shrinkage curves allows us to determine 3 critical water content values, which define different drying zones where extragranular, intragranular or mixed limitations prevail. When drying is externally controlled. the decrease of the drying rate observed during experiments can be related to the reduction of the external area of the sample, i.e., to shrinkage. When drying is internally controlled, resistances inside the solid govern the process. Between these two extreme situations, the drying rate reduction is the result of both the external area decrease and the development of internal resistances limiting drying. A multizone model is proposed to describe quantitatively these observations. The analysis of the internal texture of the Sludge extrudates reveal, crack formation at the end of the drying process. The onset of crack formation is clearly related to the appearance of internal transfer limitations. i.e., humidity and temperature gradients inside the material. [less ▲]

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See detailImaging downward granitic magma transport in the Rogaland Igneous Complex, SW norway
Bolle, Olivier ULg; Trindade, Ricardo I.F.; Bouchez, Jean-Luc et al

in Terra Nova (2002), 14(2), 87-92

Combining geological mapping and petrological, structural and geophysical (gravity and seismic) data already available for the late Proterozoic Rogaland Igneous Complex of Norway allows the 3D shape of ... [more ▼]

Combining geological mapping and petrological, structural and geophysical (gravity and seismic) data already available for the late Proterozoic Rogaland Igneous Complex of Norway allows the 3D shape of the Bjerkreim-Sokndal layered intrusion to be modelled as a thick cumulate series capped by massive granitic rocks. Using the latter data, along with the spectacular convergent linear flow pattern that covers both the cumulates and the felsic rocks of this chamber, evidence is presented to show that the granitic material was down-dragged through the sinking of its high-density mafic floor into lower density anorthosites and granulitic gneisses. This example illustrates that downward gravity-driven flows of rocks were active, in addition to upward flows, in the building of the early crust up to late-Proterozoic times, helping to explain the geochemical and structural complexities of the old crust. [less ▲]

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See detailThe plant pathogenesis-related PR-10 proteins
Elbez, Mounira; Kevers, Claire ULg; Hamdi, Saïd et al

in Acta Botanica Gallica : Bulletin de la Société Botanique de France (2002), 149(4), 415-444

The PR-10 protein family contains proteins related to pathogenesis and allergenic proteins. They are acidic proteins, with an intracellular localization, usually members of a multigene family and ... [more ▼]

The PR-10 protein family contains proteins related to pathogenesis and allergenic proteins. They are acidic proteins, with an intracellular localization, usually members of a multigene family and ubiquitous among plant kingdom. They contain a highly conserved motif, identified as a phosphate binding site. Even if the biological function of these proteins is still unknown, many indicators seem to favour the hypothesis of an RNAse activity. Moreover, one of them seems to be a cytokinin specific binding protein. Besides, PR-10 protein expression induction under cytokinin treatment was observed with the Catharanthus roseus CrPR-10a protein. Here, we present the evidence of a significative increase of endogenous cytokinin contents in leaves of transgenic Tobacco plants over-expressing the CrPR-10a protein. [less ▲]

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See detailCompte-rendu de WATIN, Michel (sous la direction de), Communication et espace public, Univers créoles I, Paris, Anthropos, 2001
Strivay, Lucienne ULg

in Quaderni, La revue de la communication (2002), 48(automne), 131-133

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See detailApproches pharmacologiques de prévention du diabète de type 2.
SCHEEN, André ULg; PAQUOT, Nicolas ULg; LETIEXHE, Michel ULg et al

in Médecine et Hygiène (2002), 60

L’augmentation rapide de la prévalence du diabète de type 2 impose la mise en place de stratégies de prévention. Outre les mesures hygiéno-diététiques, essentielles, diverses approches pharmacologiques ... [more ▼]

L’augmentation rapide de la prévalence du diabète de type 2 impose la mise en place de stratégies de prévention. Outre les mesures hygiéno-diététiques, essentielles, diverses approches pharmacologiques ont apporté récemment la preuve d’une certaine efficacité chez les sujets à risque de par la présence d’un excès pondéral et/ou d’une diminution de la tolérance au glucose. C’est le cas de plusieurs antidiabétiques oraux comme la metformine, l’acarbose ou encore la troglitazone. C’est également le cas de médicaments anti-obésité comme l’orlistat et, peut-être aussi, la sibutramine. L’inhibition du système rénine-angiotensine par un inhibiteur de l’enzyme de conversion ou par un antagoniste sélectif des récepteurs AT1 peut aussi, outre protéger contre les complications cardiovasculaires, prévenir l’apparition d’un diabète de type 2. Enfin, le rôle des médicaments hypolipidémiants reste controversé. De nouvelles études prospectives sont en cours pour confirmer ces résultats. [less ▲]

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See detailReconstruction of healthcare in Afghanistan.
Porignon, Denis ULg; Hennart, Philippe

in Lancet (2002), 359(9311), 1071-2

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See detailIdentification of bioindicator species among Ephemeroptera, Plecoptera and Trichoptera in a survey of streams belonging to the rhithral classification in the Grand Duchy of Luxembourg
Dohet, A.; Dolisy, D.; Hoffmann, L. et al

in Verhandlungen der Internationalen Vereinigung für Theoretische und Angewandte Limnologie = Proceedings of the International Association of Theoretical and Applied Limnology (2002), 28

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See detailFeasibility of a Walloon test-day model and study of its potential as tool for selection and management
Auvray, B.; Gengler, Nicolas ULg

in Interbull Bulletin (2002), 29

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See detailOxygen consumption and electron spin resonance studies of free radical production by alveolar cells exposed to anoxia: inhibiting effects of the antibiotic ceftazidime.
Mouithys-mickalad, A.; Mathy-hartert, M.; Du, G. et al

in Redox Report : Communications in Free Radical Research (2002), 7(2), 85-94

By EPR spectroscopy, we investigated free radical production by cultured human alveolar cells subjected to anoxia/re-oxygenation (A/R), and tested the effects of ceftazidime, an antibiotic previously ... [more ▼]

By EPR spectroscopy, we investigated free radical production by cultured human alveolar cells subjected to anoxia/re-oxygenation (A/R), and tested the effects of ceftazidime, an antibiotic previously demonstrated to possess antioxidant properties. Two A/R models were performed on type II pneumocytes (A549 cell line), either on cells attached to culture dishes (monolayer A/R model; 3.5 h of anoxia, 30 min of re-oxygenation) or after cell detachment (suspension A/R model; 1 h of anoxia, 10 min of re-oxygenation). Ceftazidime and selective inhibitors (SOD, Tiron, L-NMMA) were added before anoxia. Free radical production was assessed by the EPR spin trapping technique. Oxygen consumption was monitored, in parallel with EPR studies, in the suspension A/R model. The production of free radical species was demonstrated by the generation of PBN-radical adducts: (a(N) = 15.2 G) in the monolayer A/R model and a six-line EPR spectrum (a(N) = 15.7 G and a(H) = 2.7 G) in the suspension A/R model. A kinetic study performed by oximetry, in parallel with EPR spectroscopy, demonstrated marked alterations of the cell respiratory function and that the free radical production started during anoxia and increased during re-oxygenation. In the suspension A/R model, the amplitude of EPR spectra were decreased upon the addition of 200 U/ml SOD (37% inhibition), 0.1 mM Tiron (67% inhibition) and 1 mM L-NMMA (43% inhibition). Addition of 1 mM ceftazidime decreased the amplitude of EPR spectra (37% inhibition) in both A/R models. Complementary in vitro EPR studies demonstrated that CAZ scavenged the hydroxyl radical (produced by the Fenton reaction). The protective effect of ceftazidime in the cell model could thus be linked to its ability to scavenge superoxide anions, nitrogen-derived species and hydroxyl radicals. [less ▲]

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See detailCultural characteristics, pathogenicity and vegetative compatibility of Fusarium udum isolates from pigeonpea (Cajanus Cajan (L.) Millsp.) in Kenya
Kiprop, E. K.; Mwang'Ombe, A. W.; Baudoin, Jean-Pierre ULg et al

in European Journal of Plant Pathology (2002), 108(2), 147-154

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See detailFrontal hypometabolism does not explain inhibitory dysfunction in Alzheimer disease
Collette, Fabienne ULg; Van der Linden, Martial ULg; Delrue, Gaël ULg et al

in Alzheimer Disease and Associated Disorders (2002), 16(4, Oct-Dec), 228-238

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with ... [more ▼]

A series of tasks assessing inhibitory processes was administered to patients with Alzheimer disease and control subjects. Two groups of patients with Alzheimer disease were examined: patients with hypometabolism restricted to the posterior (temporal and parietal) cerebral areas and patients with hypometabolism in both posterior and anterior (frontal) cerebral areas. The performances of the patients with Alzheimer disease were inferior to those of control subjects on all inhibitory tasks, but the two groups of patients obtained similar scores. These data indicate that frontal lobe hypometabolism is not necessary to produce inhibitory impairment in Alzheimer disease. Consequently, inhibitory dysfunction could be the consequence of a (partial) disconnection process between posterior and anterior cerebral areas. [less ▲]

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See detailRapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.
Limbourg, Florian P; Huang, Zhihong; Plumier, Jean-Christophe ULg et al

in Journal of Clinical Investigation (2002), 110(11), 1729-38

Many cellular responses to corticosteroids involve the transcriptional modulation of target genes by the glucocorticoid receptor (GR). A rapid, non-nuclear effect of GR was found to mediate ... [more ▼]

Many cellular responses to corticosteroids involve the transcriptional modulation of target genes by the glucocorticoid receptor (GR). A rapid, non-nuclear effect of GR was found to mediate neuroprotection. High-dose corticosteroids (20 mg/kg intraperitoneally), given within 2 hours of transient cerebral ischemia, acutely increased endothelial nitric oxide synthase (eNOS) activity, augmented regional cerebral blood flow (CBF) by 40% to 50%, and reduced cerebral infarct size by 32%. These neuroprotective effects of corticosteroids were abolished by the GR antagonist RU486 and by inhibition of phosphatidylinositol 3-kinase (PI3K), and were absent in eNOS(-/-) mice. To determine the mechanism by which GR activated eNOS, we measured the effect of corticosteroids on PI3K and the protein kinase Akt. In a ligand-dependent manner, GR activated PI3K and Akt in vitro and in vivo caused NO-dependent vasodilation, which was blocked by cotreatment with RU486 or the PI3K inhibitor LY294002 but not by transcriptional inhibitors. Indeed, a mutant GR, which cannot dimerize and bind to DNA, still activated PI3K and Akt in response to corticosteroids. These findings indicate that non-nuclear GR rapidly activates eNOS through the PI3K/Akt pathway and suggest that this mechanism mediates the acute neuroprotective effects of corticosteroids through augmentation of CBF. [less ▲]

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See detailSaussure entre deux épistémologies
Badir, Sémir ULg

in Le français moderne (2002), 70(2), 231-238

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See detailLes figures féminines dans le théâtre de Jean-Marie Piemme
Delhalle, Nancy ULg

in Alternatives Théâtrales (2002), (75),

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See detailYBa2Cu3O7 tapes prepared by sol-gel deposition techniques: microstructure and structural characterizations
Marguillier, David ULg; Cloots, Rudi ULg; Rulmont, André ULg et al

in Physica C: Superconductivity (2002), 372(Part 2), 715-718

We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the ... [more ▼]

We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the substrate, the use of a buffer layer, and the conditions used to prepare appropriate superconducting YBa2Cu3O7,, materials. We report also on the microstructural characterizations performed in order to evaluate the crystallites size, degree of orientation and connectivity. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailEffects of prolactin deficiency on myelopoiesis and splenic T lymphocyte proliferation in thermally injured mice.
Dugan, Amy L.; Thellin, Olivier ULg; Buckley, Donna J. et al

in Endocrinology (2002), 143(10), 4147-4151

The importance of prolactin (PRL) in mammopoiesis and milk production is undisputed. However, previous studies investigating the role of PRL in immune function have yielded inconsistencies. These ... [more ▼]

The importance of prolactin (PRL) in mammopoiesis and milk production is undisputed. However, previous studies investigating the role of PRL in immune function have yielded inconsistencies. These inconsistencies have led to our hypothesis that the immunomodulatory effects of PRL are only manifest under conditions in which the organism is subjected to stress. Thermal injury is a well-known stressor. The goal of this study was to determine whether the lack of PRL enhanced the negative effects of thermal injury-induced immune alterations utilizing a mouse model in which the PRL gene had been disrupted. Mice received either sham or burn treatment, and were sacrificed 4 days later. The immune parameters studied were the capacity of bone marrow cells to form granulocyte-macrophage colony forming units (GM-CFU) in the presence of granulocyte-macrophage colony stimulating factor, and the ability of the splenic T lymphocytes to proliferate in response to phytohemagglutin (PHA). As shown by others, our results reveal that burn increased the number of GM-CFU compared to sham controls; however, this elevation was only significant in the PRL-/- mice. Thermal injury increased PHA-stimulated proliferation of splenic T lymphocytes, however this increase was only significant in the PRL+/- group. We conclude that under conditions of a controlled stress event (thermal injury) [a] the increase in the GM-CFU is exaggerated in the absence of PRL, and [b] the enhancement of PHA-induced proliferation of splenic lymphocytes required PRL. This study supports the hypothesis that the immunomodulatory effects of PRL are manifest when the organism is subjected to stress. [less ▲]

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See detailPerspectives de dialogue entre des neuromédiateurs et les kératinocytes.
Pierard-Franchimont, Claudine ULg; Faska, N.; Nikkels, Arjen ULg et al

in Dermatologie Actualité (2002), 65

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ... [more ▼]

Les neuromédiateurs contrôlant l’activité de l’axe hypothalamo-hypophysaire sont aussi exprimés dans la peau. D’autres neuromédiateurs liés au stress le sont également. En fait, près d’une vingtaine de ces molécules sont synthétisées in situ et sont connues pour avoir des récepteurs spécifiques et exprimer une activité biologique dans cet organe. Certaines exercent un impact fonctionnel sur les kératinocytes. Il s’agit en fait de systèmes paracrines neuro-kératinocytaires et autocrines par lesquels les kératinocytes expriment de nombreux récepteurs pour les neuromédiateurs qu’ils libèrent eux-mêmes. [less ▲]

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See detailThe photorefractive effect at large modulation depth in semiconductors with multiple defect levels
Nguyen, Ngoc Duy ULg; Schmeits, Marcel ULg

in Applied Physics B : Lasers & Optics (2002), 74

The photorefractive effect in semiconducting mate- rials with multiple defects is studied in the case of modulation depth m = 1. The basic equations are Poisson's equation and the continuity equations for ... [more ▼]

The photorefractive effect in semiconducting mate- rials with multiple defects is studied in the case of modulation depth m = 1. The basic equations are Poisson's equation and the continuity equations for electrons, holes and occupied defect levels. They include all recombination and optical generation mechanisms between the defect levels and valence and conduc- tion bands. Their explicit numerical solution yields microscopic quantities such as space- and time-dependent electrical field profiles, carrier concentrations, as well as generation and re- combination rates. The fundamental Fourier component of the electric field yields the two-wave-mixing gain. Application is made for InP with two levels in the forbidden gap, for which steady-state and transient resulting quantities are shown. The re- sulting features at large modulation depth are of non-sinusoidal shape. Due to the complexity of the system, the final results strongly depend on all parameters intervening in the models used, as is illustrated for several typical cases. [less ▲]

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See detailWeight loss does not influence energy expenditure or leucine metabolism in obese cats
Nguyen, Patrick; Dumon, Henri; Martin, Lucile et al

in Journal of Nutrition (2002), 132(6, Suppl. 2), 1649-1651

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See detailPollution chimique de l'environnement et risque toxique pour l'homme. Le rôle particulier des dérivés pesticides organochlorés
Charlier, Corinne ULg; Plomteux, Guy ULg

in Annales de Biologie Clinique (2002), 60(1, Jan-Feb), 37-46

There is an increasing concern about environmental exposure to multiple chemicals and adverse changes in reproductive development, function, or behaviour in wildlife. The major group of environmental ... [more ▼]

There is an increasing concern about environmental exposure to multiple chemicals and adverse changes in reproductive development, function, or behaviour in wildlife. The major group of environmental chemicals, such as organochlorine pesticides, polychlorinated biphenyls (PCBs) and other xenoestrogens are currently known to have estrogenic effects in vertebrates or fishes. Recent studies suggest that past exposure to such estrogenic compounds may affects the risk of developing breast cancer, precocious puberty, or impaired fertility in man. [less ▲]

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See detailElevated atmospheric CO2 in open top chambers increases net nitrification and potential denitrification
Carnol, Monique ULg; Hogenboom, L.; Jach, M. E. et al

in Global Change Biology (2002), 8

The control of soil nitrogen (N) availability under elevated atmospheric CO2 is central to predicting changes in ecosystem carbon (C) storage and primary productivity. The effects of elevated CO2 on ... [more ▼]

The control of soil nitrogen (N) availability under elevated atmospheric CO2 is central to predicting changes in ecosystem carbon (C) storage and primary productivity. The effects of elevated CO2 on belowground processes have so far attracted limited research and they are assumed to be controlled by indirect effects through changes in plant physiology and chemistry. In this study, we investigated the effects of a 4-year exposure to elevated CO2 (ambient + 400 mumol mol(-1) ) in open top chambers under Scots pine (Pinus sylvestris L) seedlings on soil microbial processes of nitrification and denitrification. Potential denitrification (DP) and potential N-2 O emissions were significantly higher in soils from the elevated CO2 treatment, probably regulated indirectly by the changes in soil conditions (increased pH, C availability and NO3 (-) production). Net N mineralization was mainly accounted for by nitrate production. Nitrate production was significantly larger for soil from the elevated CO2 treatment in the field when incubated in the laboratory under elevated CO2 (increase of 100%), but there was no effect when incubated under ambient CO2 . Net nitrate production of the soil originating from the ambient CO2 treatment in the field was not influenced by laboratory incubation conditions. These results indicate that a direct effect of elevated atmospheric CO2 on soil microbial processes might take place. We hypothesize that physiological adaptation or selection of nitrifiers could occur under elevated CO2 through higher soil CO2 concentrations. Alternatively, lower microbial NH4 assimilation under elevated CO2 might explain the higher net nitrification. We conclude that elevated atmospheric CO2 has a major direct effect on the soil microbial processes of nitrification and denitrification despite generally higher soil CO2 concentrations compared to atmospheric concentrations. [less ▲]

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See detailLipid-Interacting Properties Of The N-Terminal Domain Of Human Apolipoprotein C-III
Lins, Laurence ULg; Flore, Christelle ULg; Chapelle, L. et al

in Protein Engineering (2002), 15(6), 513-20

The lipid-interacting properties of the N-terminal domain of human apolipoprotein C-III (apo C-III) were investigated. By molecular modeling, we predicted that the 6-20 fragment of apo C-III is obliquely ... [more ▼]

The lipid-interacting properties of the N-terminal domain of human apolipoprotein C-III (apo C-III) were investigated. By molecular modeling, we predicted that the 6-20 fragment of apo C-III is obliquely orientated at the lipid/water interface owing to an asymmetric distribution of the hydrophobic residues when helical. This is characteristic of 'tilted peptides' originally discovered in viral fusion proteins and later in various proteins including some involved in lipoprotein metabolism. Since most tilted peptides were shown to induce liposome fusion in vitro, the fusogenic capacity of the 6-20 fragment of apo C-III was tested on unilamellar liposomes and compared with the well characterized SIV fusion peptide. Mutants were designed by molecular modeling to assess the role of the hydrophobicity gradient in the fusion. FTIR spectroscopy confirmed the predominantly helical conformation of the peptides in TFE solution and also in lipid-peptide complexes. Lipid-mixing experiments showed that the apo C-III (6-20) peptide is able to increase the fluorescence of a lipophilic fluorescent probe. The vesicle fusion was confirmed by core-mixing and leakage assays. The hydrophobicity gradient plays a key role in the fusion process because the mutant with no hydrophobic asymmetry but the same mean hydrophobicity as the wild type does not induce significant lipid fusion. The apo C-III (6-20) fragment is, however, less fusogenic than the SIV peptide, in agreement with their respective mean hydrophobicity. Since lipid fusion should not be the physiological function of the N-terminal domain of apo CIII, we suggest that its peculiar distribution of hydrophobic residues is important for the lipid-binding properties of apo C-III and should be involved in apolipoprotein and lipid exchanges crucial for triglyceride metabolism. [less ▲]

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See detailBiocontrol Of Listeria Monocytogenes In A Model Cultured Milk (Lben) By In Situ Bacteriocin Production From Lactococcus Lactis Ssp Lactis
Benkerroum, N.; Ghouati, Y.; Ghalfi, H. et al

in International Journal of Dairy Technology (2002), 55(3),

Bacteriocin-producing (Bac+) Lactococcus lactis ssp. lactis CCMM/IAV/BK1 isolated from traditional lben was used in the preparation of lben from pasteurized milk to assess its potential inhibitory ... [more ▼]

Bacteriocin-producing (Bac+) Lactococcus lactis ssp. lactis CCMM/IAV/BK1 isolated from traditional lben was used in the preparation of lben from pasteurized milk to assess its potential inhibitory activity against Listeria monocytogenes ATCC 7644. Production of bacteriocin (arbitrary units, AU) in MRS broth fortified with yeast extract (MRSY) in a fermentor under controlled and uncontrolled pH conditions was also investigated. This Bac+ strain yielded about 35 times more bacteriocin when the pH was maintained constant at 6.5 than under varying pH conditions. To test the effect of in situ bacteriocin production against L. monocytogenes, lben was made from cow's milk artificially contaminated with approximately 107 cfu/mL and fermented with a mixed mesophilic starter culture consisting of the lactococcal Bac+ organism and Lc. lactis ssp. lactis biovar diacetylactis 66, a diacetyl-producing strain, in a ratio of 1 : 1. Numbers of L. monocytogenes were monitored during fermentation and storage of lben at refrigeration temperature (c. 7°C) for up to 6 days. Performances of the Bac+ starter were compared to those of an isogenic Bac- derivative strain obtained from the Bac+ starter by curing with ethidium bromide. The results showed that the amount of L. monocytogenes decreased to below the detectable level in a 1-mL sample within 24 h of storage at 7°C in lben fermented with the Bac+ starter culture. On the contrary, L. monocytogenes survived for 6 days of storage at 7°C in lben made with the Bac- starter. The Bac+ wild strain of the starter studied could be adequately used to produce lben or similar indigenous fermented milks of improved hygienic quality on an industrial scale. Alternatively, it could be used as an adjunct in minimally processed products or in products obtained from raw milk to add a safety factor. [less ▲]

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See detailL’entomophagie : une question de culture ?
Mignon, Jacques ULg

in Tropicultura (2002), 20(3), 151-155

Entomophagy: How to Overcome our European Aversion? Entomophagy, the eating of insects, is not a curiosity but is practiced throughout the world, except in Europe and in North-America. For many Europeans ... [more ▼]

Entomophagy: How to Overcome our European Aversion? Entomophagy, the eating of insects, is not a curiosity but is practiced throughout the world, except in Europe and in North-America. For many Europeans, the consumption of insects is considered as a primitive and a repugnant comportment. An experiment, conducted in Belgium (Gembloux) has shown that, informed about the cultural, the nutritional and the ecological aspects of entomophagy, Westerners are able to surmount their aversion. Could insects become common dish in European and American restaurants? [less ▲]

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See detailAromatic Side-Chain Interactions In Proteins. I. Main Structural Features
Thomas, Annick ULg; Meurisse, R.; Charloteaux, Benoît ULg et al

in Proteins-Structure Function and Genetics (2002), 48(4), 628-34

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency ... [more ▼]

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency distribution of the shortest interatomic distance of partners is bimodal with a sharp peak at approximately 3.8 A and a wider one at a longer distance. Only the 3.8 A peak corresponds to direct ring-ring interactions thus aromatic pairs. The aromatic pairs were separated into two classes, near-sequence pairs and far-sequence pairs. Near sequence pairs stabilize local structure, and far-sequence pairs stabilize tertiary structure. Far-sequence pairs (74% of all pairs) mainly bridge two beta-strands, followed by pairs that bridge a beta-strand and a helix, and pairs that bridge a beta-strand and a random coil structure. Pairs that bridge helices are rare. The secondary structure of the near-sequence pairs depends on the partner distance in the sequence. When the partners are 1, 3, or 4 residues apart in the sequence, pairs are mostly found in helical structures. When the partners are two apart, pairs are mostly found in the same beta-strand. Analysis of the frequency of near sequence pairs supports the hypothesis that aromatic pairing occurs after, rather than before, the formation of secondary structures. [less ▲]

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See detailQuelques Névroptères d’un site de la région liégeoise (ru de Targnon, Theux, Belgique)
Mignon, Jacques ULg

in Notes Fauniques de Gembloux (2002), 47

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See detailL'accroissement des compétences régionales en matière de fiscalité immobilière. Quelques pistes nouvelles pour la Région wallonne
Jurion, Bernard ULg

in Les Cahiers de l'Urbanisme, Ministère de la Région wallonne (2002)

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See detailDesign of structural joints in building frames
Jaspart, Jean-Pierre ULg

in Progress in Structural Engineering and Materials (2002), 4(1), 18-34

A single and unified concept for the design of structural joints in building frames made of any material has been developed in recent years, and is now widely implemented in European design codes. In the ... [more ▼]

A single and unified concept for the design of structural joints in building frames made of any material has been developed in recent years, and is now widely implemented in European design codes. In the present paper, this concept is presented, its merits as far as the economy of a project are demonstrated, and practical design tools for its application in daily practice are briefly described. The paper also contains references to user's manuals and design handbooks. [less ▲]

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See detailFracture prevention in postmenopausal women.
Bruyère, Olivier ULg; Edwards, John; Reginster, Jean-Yves ULg

in Clinical Evidence (2002), 8

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See detailPresence in bovine enteropathogenic (EPEC) and enterohaemorrhagic (EHEC) Escherichia coli of genes encoding for putative adhesins of human EHEC strains
Szalo, Ioan Mihai ULg; Goffaux, Frédéric; Pirson, Vinciane et al

in Research in Microbiology (2002), 153(10), 653-658

Enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC) infections are characterised by the formation of attaching and effacing lesions on intestinal epithelial cells. The first step of ... [more ▼]

Enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC and EHEC) infections are characterised by the formation of attaching and effacing lesions on intestinal epithelial cells. The first step of EPEC and EHEC pathogenesis involves the initial adherence of the bacterium to the intestinal epithelium. A collection of bovine EPEC and EHEC strains belonging to different serogroups was tested by colony blot hybridization with gene probes for putative adhesins (BFPA, LPFA, IHA, LIFA) of human EPEC and EHEC, and also for fimbrial and afimbrial adhesins (AFA8, F17, Cs31A) of bovine necrotoxigenic E. coli (NTEC). In the bovine EPEC and EHEC strains tested, sequences homologous to lifA, ihA, and lpfA genes were detected, sometimes in association with particular serogroups. Bovine O26 EPEC also possessed a sequence homologous to a gene of the clp operon, coding for the CS31A adhesin, associated with bovine NTEC. Overall results showed that different genes encoding for putative adhesins of human EHEC strains are present in bovine EPEC and EHEC strains, but not one of them is present in all strains. [less ▲]

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See detailBright Spots and the Question of Hafting
Rots, Veerle ULg

in Anthropologica et Praehistorica : Bulletin de la Société Royale Belge d'Anthropologie et de Préhistoire (2002), 113

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See detailLa recherche scientifique en Hautes-Fagnes
Streel, Maurice ULg

in Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Sciences (2002), XIII(1-6), 55-65

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See detailGenetic diversity of the african geocarpic legume kersting's groundnut, Macrotyloma geocarpum (Tribe Phaseoleae : Fabaceae)
Pasquet, R. S.; Mergeai, Guy ULg; Baudoin, Jean-Pierre ULg

in Biochemical Systematics & Ecology (2002), 30(10), 943-952

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See detailQualité et action publique
Mormont, Marc ULg

in Pyramides (2002), 5

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See detailQuelques considérations techniques sur la construction, les transformations et l'état matériel de la tour valenciennoise, à Mons
Houbart, Claudine ULg

in Mémoires et Publications de la Société des Sciences, des Arts et des Lettres du Hainaut (2002), CI

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See detailThe antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells
Hajitou, Amin; Grignet, Christine ULg; Devy, L. et al

in FASEB Journal (2002), 16

Endostatin and angiostatin are known as tumor-derived angiogenesis inhibitors, but their mechanisms of action are not yet completely defined. We report here that endostatin and angiostatin, delivered by ... [more ▼]

Endostatin and angiostatin are known as tumor-derived angiogenesis inhibitors, but their mechanisms of action are not yet completely defined. We report here that endostatin and angiostatin, delivered by adenoviral vectors, reduced in vitro the neovessel formation in the mouse aortic ring assay by 85 and 40%, respectively. We also demonstrated in vivo that both endostatin and angiostatin inhibited local invasion and tumor vascularization of transplanted murine malignant keratinocytes, and reduced by 50 and 90% the development of highly vascularized murine mammary tumors. This inhibition of tumor growth was associated with a reduction of tumor vascularization. Expression analysis of vascular endothelial growth factor (VEGF) carried out in the mouse aortic ring model revealed a 3- to 10-fold down-regulation of VEGF mRNA expression in endostatin-treated rings. A similar down-regulation of VEGF expression at both mRNA and protein levels was also observed in the two in vivo cancer models after treatment with each angiogenesis inhibitor. This suggests that endostatin and angiostatin effects may be mediated, at least in part, by their ability to down-regulate VEGF expression within the tumor. This work provides evidence that endostatin and angiostatin act on tumor cells themselves. [less ▲]

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See detailHyperfine structure of neutral vanadium lines and livels
Lefèbvre, P.-H.; Garnir, Henri-Pierre ULg; Biémont, Emile ULg

in Physica Scripta (2002), 66

We have recorded hollow-cathode spectra of neutral vanadium by Fourier transform spectroscopy in the near infrared - visible region (9000-17 000 cm-1). 36 transitions showing hyperfine structure have been ... [more ▼]

We have recorded hollow-cathode spectra of neutral vanadium by Fourier transform spectroscopy in the near infrared - visible region (9000-17 000 cm-1). 36 transitions showing hyperfine structure have been analyzed, allowing us to deduce magnetic dipole constants for 27 levels belonging to the 3d44p and 3d34s4p configurations. For 22 of these levels no data were previously available. [less ▲]

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See detailThe lichen flora of the Boulonnais (France, Pas-de-Calais)
Sparrius, L.B.; Diederich, Paul; Signoret, Jonathan et al

in Belgian Journal of Botany (2002), 135

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See detailAxillary artery injury secondary to anterior shoulder dislocation: report of two cases.
MAWEJA, Sylvie ULg; SakalihasanN, Natzi ULg; VAN DAMME, Hendrik ULg et al

in Acta Chirurgica Belgica (2002), 102(3), 187-91

Vascular injuries secondary to isolated shoulder dislocation are rare. Unawareness for closed axillary artery trauma by many physicians treating shoulder dislocations, counts often for missed or delayed ... [more ▼]

Vascular injuries secondary to isolated shoulder dislocation are rare. Unawareness for closed axillary artery trauma by many physicians treating shoulder dislocations, counts often for missed or delayed diagnosis. The authors describe two cases that presented with an anterior shoulder dislocation, complicated by a disruption of the axillary artery with subsequent thrombosis. The various pathogenic mechanisms are discussed. The pathognomic triad consists of anterior shoulder dislocation, absent or diminished distal pulse and an axillary protruding hematoma. Prompt surgical arterial repair is mandatory. [less ▲]

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See detailIdentification d'une loi thermo-élasto-viscoplastique en vue de la modélisation du laminage à chaud du cuivre
Moureaux, P.; Moto Mpong, S.; Remy, M. et al

in Journal de Physique IV (2002), 102

la mise au point d'un modèle de simulation de la dernière passe du laminage à chaud du cuivre ne présente à priori pas de problème du point de vue numérique pour un code d'éléments finis non linéaire. La ... [more ▼]

la mise au point d'un modèle de simulation de la dernière passe du laminage à chaud du cuivre ne présente à priori pas de problème du point de vue numérique pour un code d'éléments finis non linéaire. La collecte d'informations précises tant sur le procédé industriel que sur le comportement du matériau est par contre une opération non triviale. Cet article présente les diverses méthodes expérimentales mises en œuvre pour caractériser le matériau: essais de compression à chaud, mesures d'analyse thermique différentielle, essais de dilatométrie et de diffusivité. Les méthodes permettant d'identifier les paramètres de la loi élasto-visco-plastique de type Norton-Hoff à partir des essais sont présentées et une analyse bibliographique investigue le problème de la détermination du module de Young à haute température. Tant les hypothèses supplémentaires relatives au procédé et nécessaires au modèle que les résultats finaux sont résumés. [less ▲]

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See detailLes adhésifs de cinquième génération
Gueders, Audrey ULg

in Actualités Dentaires de l'Université de Liège (2002), 30

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See detailChanges in the development of the winter-spring phytoplankton bloom in the Bay of Calvi (NW Mediterranean) over the last two decades: a response to changing climate?
Goffart, Anne ULg; Hecq, Jean-Henri ULg; Legendre, Louis

in Marine Ecology. Progress Series (2002), 236

The development of the winter-spring phytoplankton bloom was investigated in the Bay of Calvi (Corsica, Ligurian Sea, northwestern Mediterranean) in 1979, 1986, 1988, 1997 and 1998. A drastic reduction of ... [more ▼]

The development of the winter-spring phytoplankton bloom was investigated in the Bay of Calvi (Corsica, Ligurian Sea, northwestern Mediterranean) in 1979, 1986, 1988, 1997 and 1998. A drastic reduction of phytoplankton biomass was evidenced over the last 2 decades, in relation to long-term changes in climatic and environmental conditions. Between 1979 and 1998, the monthly averaged chlorophyll a concentrations at 1 m decreased by about 80% during February, March and April. Simultaneously, major changes to hydrodynamic conditions include warmer water, overall decrease of salinity at 10 m depth, longer periods of bright sunshine and lower wind stress, The changes in environmental conditions were large enough to affect the vertical stability of the water column during the winter-spring period and to reduce nutrient replenishment of the surface layer prior to the usual period of phytoplankton growth. Until 1986, the main factor driving nutrient replenishment was the winter upward mixing of nutrient-rich deep waters, while the progressive reduction of mixing from 1988 induced nutrient limitation of surface waters in the last decade. The following hypotheses on changes in the development of the winter-spring phytoplankton bloom are made: (1) Until 1986, phytoplankton peaks took place in relatively high-nutrient waters and were diatom-dominated. (2) Between 1986 and 1988, decreasing Si availability led to Si limitation which caused a reduction in diatom abundance. This resulted in the disappearance of the diatom-dominated pulses and in lower phytoplankton biomass and was accompanied by a shift toward non-siliceous phytoplankton. (3) In 1988, 1997 and 1998, decreasing nitrate availability led to nitrate limitation, thus explaining the progressive reduction in non-siliceous phytoplankton biomass. Other, associated changes in benthos assemblages and ichthyofauna are documented. The conclusions from the Bay of Calvi are extended to the whole western Corsican coast. This confirms that the Mediterranean reacts rapidly to external perturbations, which are driven by climate change in that particular area. [less ▲]

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See detailSubclinical speckled perifollicular melanosis of the scalp.
Petit, Ludivine; Saint Leger, Didier; Loussouarn, Genevieve et al

in European Journal of Dermatology (2002), 12(6), 565-8

Based on the clinical presentation of some skin pigmentation disorders it is thought that a bicompartmental functional system exists in the epidermal melanocyte population. It corresponds to the ... [more ▼]

Based on the clinical presentation of some skin pigmentation disorders it is thought that a bicompartmental functional system exists in the epidermal melanocyte population. It corresponds to the perifollicular and interfollicular compartments, respectively. The present study was undertaken looking for the presence of such a system on scalp unaffected by pigmentary disorders. The scalps of 100 men with incipient to severe androgenic alopecia were examined using a videocamera equipped with an internal ultraviolet light-emitting unit. The face, trunk and limbs were similarly examined in 45 of these adults and in 13 children of both sexes. In 92 men, a subclinical hypermelanosis was found as a speckled pattern centered on every single follicle. With increasing baldness severity, another epidermal hyperpigmentation pattern involving the interfollicular area was superimposed to the perifollicular pattern. These stereotyped patterns of subclinical melanoderma were also disclosed on the face of adults, but not in children. In addition, the spotty perifollicular pattern was discrete or not apparent on the other parts of the body. It is concluded that the perifollicular subclinical melanotic pattern is a regional characteristic of cephalic skin, perhaps related to the local production of melanocortins, particularly alpha-MSH by the pilosebaceous unit. [less ▲]

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See detailThe Offense of Hooliganism and the Moral Dimension of China's Pursuit of Modenrity
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2002), Vol. XVIII

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See detailContinuity preserving modified maximum cross-correlation technique
Zavialov, Peter O.; Grigorieva, Julia V.; Moller, Osmar O. et al

in Journal of Geophysical Research. Oceans (2002), 107(C10, SEP-OCT),

The maximum cross-correlation (MCC) method reconstructs the surface advective velocity fields from the displacements of spatial patterns in pairs of sequential satellite (normally infrared) images ... [more ▼]

The maximum cross-correlation (MCC) method reconstructs the surface advective velocity fields from the displacements of spatial patterns in pairs of sequential satellite (normally infrared) images. However, the performance of the conventional MCC method is not always satisfactory. One of the main reasons for this is the fact that the method can correctly estimate only the velocity component parallel to the gradient of the property depicted in the images, while any small displacement perpendicular to the gradient (i.e., directed along the isolines) essentially maps the spatial pattern onto itself and therefore can not be detected using the conventional MCC technique. In the present work we propose a modification of the MCC method that allows circumventing this basic deficiency and improving the performance of the MCC technique. In this approach, the "cross-isoline'' components of the velocity field are obtained as in the conventional MCC scheme; however, the "along-isoline'' components derived from the MCC are disregarded as unreliable. Instead, the "true'' along-isoline components are then reconstructed from the given cross-isoline velocity field based on the continuity requirement and on the condition of no normal flow at solid boundaries. This inverse problem is solved by constructing the two-dimensional stream function in the curvilinear coordinate frame associated with the image isolines. The method is illustrated using AVHRR images from the southwestern Atlantic Ocean and the Black Sea. The results are compared with some direct drifter and current meter measurements and geostrophic estimates. [less ▲]

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See detailEntre analyse historiciste et interdisciplinarité : Pet Sounds des Beach Boys
Pirenne, Christophe ULg

in Musurgia (2002), IX(2), 9-22

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See detailLes antagonistes calciques ont-ils une place de première ligne dans le traitement de l'hypertension artérielle?
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2002), 57(2), 79-84

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one ... [more ▼]

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one have not confirmed this provided that one uses long-acting molecule. But the real beneficial effect due to the different antihypertensive classes is mainly linked to the magnitude of the blood pressure lowering effect. [less ▲]

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See detailTraces expérimentales d’emmanchement. Identification et caractéristiques
Rots, Veerle ULg; Pirnay, Louis; Pirson, Philippe et al

in Bulletin de la Société Royale Belge d'Etudes Géologiques et Archéologiques "Les Chercheurs de Wallonie" (2002), 41

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See detailVasopressin and oxytocin reverse adenosine-induced pituicyte stellation via calcium-dependent activation of Cdc42.
Rosso, Lia; Peteri-Brunback, Brigitta; Vouret-Craviari, Valerie et al

in European Journal of Neuroscience (2002), 16(12), 2324-32

In view of the potential impact of pituicyte morphology on neurohypophysial hormone secretion, we have studied the mechanisms involved in the shape changes induced by vasopressin (AVP) and oxytocin (OXT ... [more ▼]

In view of the potential impact of pituicyte morphology on neurohypophysial hormone secretion, we have studied the mechanisms involved in the shape changes induced by vasopressin (AVP) and oxytocin (OXT) in cultured rat pituicytes. Pituicytes induced to become stellate in the presence of 10 micro m adenosine revert to their nonstellate shape approximately 20 min after application of AVP or OXT. The IC50 for this effect is 0.1 nm for AVP and 36 nm for OXT. Both agonists induce Ca2+ signals in pituicytes, comprised of a transient peak and a plateau phase that is dependent on the presence of extracellular Ca2+. The EC50 values of AVP for the transient and sustained responses are 4.5 and 0.1 nm, respectively; corresponding values for OXT are 180 and 107 nm. We determined pharmacologically that these hormone-induced Ca2+ signals are mediated by the V1a subtype of vasopressin receptors, similar to what we previously observed for hormone-induced reversal of stellation. Removal of extracellular Ca2+ or chelation of intracellular Ca2+ partially prevented AVP from reversing stellation, suggesting a role for Ca2+ in this event. We previously established that adenosine-induced stellation of pituicytes occurs via RhoA inhibition. However, pharmacological experiments and pull-down assays presented here show that AVP-induced reversal of stellation does not involve RhoA activation. Rather, AVP was found to induce a time-dependent activation of Cdc42, another small GTPase involved in cytoskeletal plasticity. Activation of Cdc42 by AVP is sensitive to intra- and extracellular Ca2+ depletion, similar to AVP-induced reversal of stellation. Furthermore, AVP-induced reversal of stellation is blocked by expression of an NWASP fragment known to inhibit endogenous Cdc42. [less ▲]

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See detailThe effect of health related quality of life on reported use of health care resources in patients with osteoarthritis and rheumatoid arthritis: a longitudinal analysis.
Ethgen, Olivier ULg; Kahler, Kristijan H; Kong, Sheldon X et al

in Journal of Rheumatology (2002), 29(6), 1147-55

OBJECTIVE: In today's cost conscious environment, health services researchers are consistently trying to find ways to predict future health care resource utilization (HCRU) and its associated costs. We ... [more ▼]

OBJECTIVE: In today's cost conscious environment, health services researchers are consistently trying to find ways to predict future health care resource utilization (HCRU) and its associated costs. We evaluated the impact of health related quality of life (HRQL) on future HCRU in patients with arthritis. METHODS: A total of 642 patients with rheumatoid arthritis (RA) and 395 patients with osteoarthritis (OA) completed at least 2 and as many as 6 consecutive surveys at 6 mo intervals. Information collected included demographics, HRQL questionnaires [Medical Outcome Study Short Form 36 (SF-36), Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), and the Stanford Health Assessment Questionnaire (HAQ)], and HCRU over the previous 6 months. Longitudinal data analysis was perfomed to assess the effect of HRQL on future HCRU. RESULTS: Statistically significant associations between HCRU and HRQL variables were noted. Higher rates of HCRU were found in those in the worst quarter compared with those in the best quarter of HRQL. With the HAQ, OA and RA patients in the worst quarter reported a 199% (p < 0.05) and 48% (p < 0.05) increase in rheumatologist visits, respectively. With the WOMAC Function, increases were as high as 196% (p < 0.05) in rheumatologist visits for patients with OA. Patients with RA with a high level of HRQL as measured by the SF-36 (physical component score) reported a decrease of 31% (p < 0.01) in general practitioner visits and a decrease of 52% (p < 0.01) in hospitalization (mental component score). CONCLUSION: These findings suggest that HRQL may be used to predict future health care consumption. Such an approach may lead to a more efficient allocation of resources by providing useful information to health care providers and health care decision makers. [less ▲]

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See detailThe use of placebo-controlled and non-inferiority trials for the evaluation of new drugs in the treatment of postmenopausal osteoporosis
Delmas, P. D.; Calvo, Gisèle ULg; Boers, M. et al

in Osteoporosis International (2002), 13(1), 1-5

Registration of new agents for the treatment of postmenopausal osteoporosis has been based over the past few years on placebo-controlled phase III trials with the incidence of patients with new vertebral ... [more ▼]

Registration of new agents for the treatment of postmenopausal osteoporosis has been based over the past few years on placebo-controlled phase III trials with the incidence of patients with new vertebral/nonvertebral fractures as the most usual primary endpoint. The use of a placebo in diseases where an active treatment is available has been a matter of debate following the update of the Declaration of Helsinki by the World Medical Association which questioned this trial design. Current regulatory recommendations within the European Union suggest that placebo-controlled trials are still the best option when assessing the efficacy and safety of new drugs intended for the treatment of postmenopausal osteoporosis. This suggestion seems to be in apparent contradiction with the current content of the Declaration of Helsinki. This paper addresses the ethics and feasibility of placebo-controlled trials in the treatment of postmenopausal osteoporosis, in the light of available therapeutic options, and discusses possible alternative approaches in those patients where placebo treatment could be deemed to be unethical. It is concluded that placebo-controlled trials remain the most efficient design to establish the efficacy and safety of a new agent for the treatment of postmenopausal osteoporosis. Such trials are feasible and ethically acceptable in patients with osteoporosis but without prevalent vertebral fractures. Conversely, in patients with prevalent vertebral fractures, placebo-controlled trials are ethically questionable and non-inferiority trials are more appropriate. A relative margin of non inferiority of 20-30% is suggested, to be discussed on a case by case basis. [less ▲]

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See detailApplication of the laser beam deflection to the study of temperature filed and heat transfer in natural convection,
Cerisier, P.; Sylvain, J. D.; Dauby, Pierre ULg

in Experiments in Fluids (2002), 33

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See detailGeochemistry of bitter brines in the Salar de Coipasa - Bolivia
Lebrun, Vincent; Pacosillo, Pedro; Gutierrez, Jorge et al

in Aardkundige Mededelingen (2002), 12

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See detailEvolution des donnees maternelles et perinatales recueillies en routine entre 1980 et 1998 a la maternite de reference de Rutshuru en Republique democratique du Congo. II. Deces du nouveau-ne et naissances de faible poids.
Mugisho, Etienne; Dramaix, Michele; Porignon, Denis ULg et al

in Sante (Montrouge, France) (2002), 12(2), 252-5

This second paper aims at deriving useful information allowing to improve the strategy applied for maternal health care. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were ... [more ▼]

This second paper aims at deriving useful information allowing to improve the strategy applied for maternal health care. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were collected. Characteristics, mortality, morbidity of mothers and new-born and obstetrical interventions were recorded. The present work describes the evolution of low birth weight (LBW), new-born deaths, and associated risk factors. The statistical analyses applied included khi2, t-test, and multiple logistic regression. RESULTS: Eighteen percent of new-born weights below 2.5 kg and 7.9% died. The proportion of low birth weights remains globally constant. Low proportions of new-born deaths were observed in 1981, 1982, 1988 and 1998. At admission, 35% of the women presented at least one of the four risks defined by the factors used for reference; this proportion went up from 26.1 to 39.2%. The four reference factors were associated with low birth weight. Baudelocque diameter and age were not associated with new-born death. Education and BMI were associated with an increased risk of new-born death. Marital status was not associated with any of the two outcomes. CONCLUSION: This analysis shows small variation of LBWs and perinatal deaths. It confirms the association between these two outcomes and most of the risk factors studied. The efficacy of the strategies implemented for improving perinatal health is questioned. The authors recommend that they be reassessed. [less ▲]

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See detailA Set Of Primers For Amplification Of Mitochondrial Dna In Picea Abies And Other Conifer Species
Jeandroz, S.; Bastien, D.; Chandelier, A. et al

in Molecular Ecology Notes (2002), 2(4),

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See detailComposite structures optimization using sequential convex programming
Bruyneel, Michaël ULg; Fleury, Claude ULg

in Advances in Engineering Software (2002), 33(7-10), 697-711

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described ... [more ▼]

The design of composite structures is considered here. The approximation concepts approach is used to solve the optimization problem. The convex approximations of the MMA family are briefly described. Several modifications of these approximations are presented. They are now based on gradient information at two successive iterations, avoiding the use of the expensive second-order derivatives. A two-point fitting scheme is also described, where the function value at the preceding design point is used to improve the approximation. Numerical examples compare these new purely non-monotonous schemes to the existing ones for the selection of optimal fibers orientations in laminates. It is shown how these two-point based approximations are well adapted to the problem and can improve the optimization task, leading to reasonable computational efforts. A procedure is also derived for considering simultaneously monotonous and non-monotonous structural behaviors. The resulting generalized approximation scheme is well suited for the optimization of composite structures when both plies thickness and fibers orientations are considered as design variables. It is concluded that the newly developed approximation schemes of the MMA family are reliable for composite structures optimization. All the studied approximations are convex and separable: the optimization problem can then be solved using a dual approach. (C) 2002 Civil-Comp Ltd and Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailSteroid receptor coactivator SRC-1 exhibits high expression in steroid-sensitive brain areas regulating reproductive behaviors in the quail brain.
Charlier, Thierry ULg; Lakaye, Bernard ULg; Ball, Gregory F et al

in Neuroendocrinology (2002), 76(5), 297-315

The steroid receptor coactivator SRC-1 modulates ligand-dependent transactivation of several nuclear receptors, including the receptors for sex steroid hormones. Reducing the expression of SRC-1 by ... [more ▼]

The steroid receptor coactivator SRC-1 modulates ligand-dependent transactivation of several nuclear receptors, including the receptors for sex steroid hormones. Reducing the expression of SRC-1 by injection of specific antisense oligonucleotides markedly inhibits the effects of estrogens of the sexual differentiation of brain and behavior in rats and inhibits the activation of female sexual behavior in adult female rats. SRC-1 thus appears to be involved in both the development and activation of sexual behavior. In the Japanese quail brain, we amplified by RT-PCR a 3,411-bp fragment extending from the HLH domain to the activating domain-2 of the protein. The quail SRC-1 is closely related to the mammalian (m) SRC-1 and contains a high proportion of GC nucleotides (62.5%). Its amino acid sequence presents 70% identity with mammalian SRC-1 and contains the three conserved LXXLL boxes involved in the interaction with nuclear receptors. In both males and females, RT-PCR demonstrates a similarly high level of expression in the telencephalon, diencephalon, optic lobes, brain stem, spinal cord, pituitary, liver, kidney, adrenal gland, heart, lung, gonads and gonoducts. Males express significantly higher levels of SRC-1 in the preoptic area-hypothalamus than females. In both sexes, lower levels of expression are observed in the cerebellum and muscles. In situ hybridization utilizing a mixture of four digoxigenin-labeled oligonucleotides confirms at the cellular level the widespread distribution of SRC-1 mRNA in the brain and a particularly dense expression in steroid-sensitive areas that play a key role in the control of male sexual behavior. These data confirm the presence and describe for the first time the SRC-1 distribution in the brain of an avian species. They confirm its broad, nearly ubiquitous, distribution in the entire body including the brain as could be expected for a coactivator that regulates to the action of many nuclear receptors. However this distribution is heterogeneous in the brain and sexually differentiated in at least some areas. The very dense expression of SRC-1 in limbic and mesencephalic nuclei that are associated with the control of male sexual behavior is consistent with the notion that this coactivator plays a significant role in the activation of this behavior. [less ▲]

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See detailRelationship between markers of blood oxidant status and physiological variables in healthy and heaves-affected horses after exercise
Kirschvink, Nathalie; Art, Tatiana ULg; de Moffarts, Brieuc et al

in Equine Veterinary Journal. Supplement (2002), 34

Exercise-induced oxidative stress is investigated as a potential performance-limiting factor in human sports medicine. Therefore, the present study aimed to assess whether physiological variables that ... [more ▼]

Exercise-induced oxidative stress is investigated as a potential performance-limiting factor in human sports medicine. Therefore, the present study aimed to assess whether physiological variables that change with exercise intensity were correlated with blood oxidant markers in healthy and heaves-affected horses. Seven healthy horses, 8 heaves-affected in remission and 7 heaves-affected in crisis performed a standardised exercise test (SET) of stepwise increasing intensity. Variables monitored during exercise were heart rate (HR), venous plasma lactate (LA), packed cell volume (PCV) and arterial oxygen tension (PaO2). Oxidant markers (uric acid [UA], 8-iso-PGF2alpha and reduced [GSH] and oxidised glutathione [GSSG]) were analysed in venous peripheral blood sampled at rest (R), at peak-exercise intensity (Emax), 15 (E15) and 60 (E60) min after SET. There was a significant effect of heaves on oxidant markers and, therefore, correlation analyses between physiological variables and oxidant markers were performed separately per horse group. In healthy horses, UA analysed at Emax was positively correlated with LA. Furthermore, GSH analysed at Emax and E15 was positively correlated with PaO2. In healthy and heaves-affected horses in remission, GSH and GSSG determined at Emax were negatively correlated with HR. There was no significant correlation between 8-iso-PGF2alpha and physiological variables. In conclusion, a correlation between the physiological response to exercise and some oxidant markers exists in healthy horses. However, in heaves-affected horses the blood oxidant status is probably more dependant on airway disease than on exercise. Future studies should be undertaken to assess whether antioxidant supplementation might positively influence the oxidant-antiodidant balance in exercising horses. [less ▲]

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See detailLa mesure de la pression artérielle : écueils et chausse-trapes
Rorive, Georges ULg; Dubois, Bernard ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2002), 57(5), 250-252

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis ... [more ▼]

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis d'identifier l'importance de l'effet consultatio et, par là, de définir l'hypertension de "la blouse blanche". Celle-ci se définit comme une pression artérielle pathologique à la consultation et strictement normale en dehors. Si on la définit de cette manière, cette pathologie ne s'accompagne pas d'une augmentation de la fréqunce des affections cardiovasculaires. Chez un tiers des patients, cependant, elle évolue vers des formes plus sévères de l'hypertension. [less ▲]

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See detailLe vol du cheval sacré
Swennen, Philippe ULg

in Acta Orientalia Belgica (2002), XVI

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See detailCoastal and Estuarine Fine Sediment Processes (book review)
Grégoire, Marilaure ULg

in Journal of Marine Systems (2002), 37

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See detailCompte rendu des actes du colloque : Unanimité et diversité cisterciennes
Delfosse, Annick ULg

in Moyen Age (Le) (2002), 108(2), 380-382

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