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See detailLe diabète insipide central : l'étiologie n'est pas toujours évidente
Geenen, Vincent ULg

in Actualité Médicale Belge (1994), 444

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See detailPreservation of Oocyte and Granulosa Cell Morphology in Bovine Preantral Follicles Cultured in Vitro
Figueiredo, J. R.; Hulshof, S. C.; Van den Hurk, R. et al

in Theriogenology (1994), 41(6), 1333-46

Described in the present paper is a culture system that preserves oocyte and granulosa cell morphology in bovine preantral follicles during 5 d in vitro. The effects of additional hypoxanthine and energy ... [more ▼]

Described in the present paper is a culture system that preserves oocyte and granulosa cell morphology in bovine preantral follicles during 5 d in vitro. The effects of additional hypoxanthine and energy substrata (i.e., pyruvate and glutamine) on the morphology of cultured preantral follicles were investigated. It was shown that addition of a mixture of pyruvate, glutamine and hypoxantine to the culture medium increased the percentage of follicles with an intact oocyte from 29.4 to 78.6%. Morphological criteria are described to discriminate between normal and degenerated preantral follicles during culture by inverted microscopy. In addition, the importance of histological evaluation to judge the quality of oocyte and granulosa cells is demonstrated. [less ▲]

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See detailTraducteurs et traductions dans l'Egypte gréco-romaine
Rochette, Bruno ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1994), 69(138), 313-322

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See detailEFFECTS OF ELECTROKINETIC CHARACTERISTICS ON THE FORMATION OF A PROTEIN MICROCRYSTALLINE CELLULOSE COMPLEX
Paquot, Michel ULg; GODIN, F.; Dumont de chassart, Q.

in Lebensmittel-Wissenschaft & -Technologie = Food Science & Technology (1994), 27(1), 11-15

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See detailCompte-rendu de Lucie Antoniol, Lire Ryle aujourd'hui. Aux sources de la philosophie analytique
Leclercq, Bruno ULg

in Revue Philosophique de Louvain (1994), 92

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See detailInfluence de la pluie sur l'utilisation d'un abri par des taurillons au pâturage
Vandenheede, Marc ULg; Sheri, R.; Nicks, Baudouin ULg et al

in Annales de Médecine Vétérinaire (1994), 138

The time spent under a shelter by 8 grazing fattening bulls of the Belgian Blue breed was recorded during 35 days using a time-lapse recorder with IR illumination. The observation period was divided into ... [more ▼]

The time spent under a shelter by 8 grazing fattening bulls of the Belgian Blue breed was recorded during 35 days using a time-lapse recorder with IR illumination. The observation period was divided into 166 hours with rain (20 %) and 674 hours without precipitation (80 %). An occupation rate was calculated for each hour as the sum of the time spent under the shelter by each of the 8 bulls divided by 480 (8 animals x 60 minutes). The average occupation rates were 15.4 +/- 29.1 % for the hours with rain and 4.5 +/- 14.8 % for the hours without precipitation (P<0.001). The occupation rate was significantly influenced by intensity and duration of the rain : the occupation rate being higher during rainfall than with dry weather when the intensity of the rain was at least 0.4 l/m2 and the duration more than 2 hours. There was no significant difference between the live weight gain of the animals with a shelter and of other bulls grazing on an adjacent pasture without shelter. Our observations suggested however that a shelter may improve the welfare of the animals. [less ▲]

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See detailHaemodynamic dysfunctions involved in experimental bovine pneumonic pasteurellosis
Desmecht, Daniel ULg; Amory, Hélène ULg; Linden, Annick ULg et al

in Journal of Experimental Animal Science (1994), 37

The present experiments were designed Co challenge, without the bias of anaesthesia, the previously reported statement that intratracheal administration of Pasteurella haemolvtica does not impair ... [more ▼]

The present experiments were designed Co challenge, without the bias of anaesthesia, the previously reported statement that intratracheal administration of Pasteurella haemolvtica does not impair haemodynamics in calves. Central venous, pulmonary arterial and capillary wedge and systemic arterial pressures were measured by fluid-filled catheters in 11 calves. Cardiac output was measured by the thermodilution technique, heart rate (HR) was derived from the ECG and stroke volume (SV), pulmonary and systemic vascular resistance were calculated. The haemodynamic values were measured hourly from the first to the tenth hour alter intratracheal inoculation of P. haemolytica. Cardiovascular response was marked and typically consisted of two hypotensive hypodynamic phases. The first, which occurred by the second hour after inoculation, consisted of a transient bradycardia and a systemic vasodilation leading to profound hypotension and reduced venous return. Cardiac performance then recovered, but systemic hypotension persisted and hypoxaemia developed. The second phase occurred by the seventh hour alter inoculation and was associated with a decline in SV, an increase in HR, and pulmonary hypertension. Three different degrees of cardiovascular dysfunctions were found, differing basically in the intensity of the first phase bradycardia and second phase reduction in SV and systemic arterial pressure, suggesting that experimental pneumonia produced by intratracheal instillation of P. haemolytica in calves results in distinct cardiovascular dysfunctions depending on the animal. Ignorance of the underlying haemodynamic status therefore precludes reliable interpretation of physiological as well as pharmacological results using this model of respiratory disease [less ▲]

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See detailAnomalie pluviométrique négative sur le Sud-est du Zaïre en janvier 1992
Kalombo, K.; Erpicum, Michel ULg; Lahuec, J. P.

in Publications de l'Association Internationale de Climatologie (1994), 7

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See detailEffect of recombinant human erythropoietin on platelets in patients with anemia of renal failure: correlation of platelet count with erythropoietic activity and iron parameters.
Beguin, Yves ULg; Loo, Martine; R'Zik, Samir ULg et al

in European Journal of Haematology (1994), 53(5), 265-70

We examined the effect of treatment with rHuEpo on platelet counts in 61 hemodialysis patients and correlated them with changes in erythropoietic activity, iron status and inflammation. Platelets (10(9)/1 ... [more ▼]

We examined the effect of treatment with rHuEpo on platelet counts in 61 hemodialysis patients and correlated them with changes in erythropoietic activity, iron status and inflammation. Platelets (10(9)/1) increased from 220 +/- 80 to 245 +/- 102 after 14 days and stabilized at that level up to day 90 (p < 0.0001). The increment was similar in complete or partial responders but was not observed in failures. Serum transferrin receptor (sTfR, a measure of total erythropoiesis) and Het rose much more progressively, but relative platelet increments correlated with relative increases in sTfR and Hct. Relative platelet increments correlated inversely with relative changes of SeFe or transferrin saturation, but not with their absolute values, nor with baseline ferritin or its progressive decrease. Although baseline platelet count was 12% higher in patients with inflammation and correlated with serum haptoglobin, relative increases were similar in patients with or without inflammation. In conclusion, rHuEpo produced a clinically minor but consistent elevation of platelet counts. These modifications were not related primarily to modifications in iron stores, functional iron deficiency, or inflammation, but paralleled the expansion of erythropoietic activity. The results suggest that rHuEpo has a small positive effect on platelet production, but it cannot be ruled out that this could be partially mediated through functional iron deficiency. [less ▲]

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See detailSelected Bibliography of Criticism on the Prose Poem
Delville, Michel ULg

in The Prose Poem: an International Journal (1994), 3

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See detailA recombinant viral haemorrhagic septicaemia virus glycoprotein expressed in insect cells induces protective immunity in rainbow trout
Lecocq-Xhonneux, F.; Thiry, M.; Dheur, I. et al

in Journal of General Virology (The) (1994), 75

Viral haemorrhagic septicaemia (VHS) is a fish rhabdovirus infection of world-wide importance. Control policies have been established but the disease still causes heavy losses in fish farming. The ... [more ▼]

Viral haemorrhagic septicaemia (VHS) is a fish rhabdovirus infection of world-wide importance. Control policies have been established but the disease still causes heavy losses in fish farming. The development of a recombinant subunit vaccine was initiated to produce a safe and effective vaccine to protect fish against VHS. The VHS virus (VHSV) glycoprotein, which induces neutralizing antibodies in rainbow trout, was chosen for expression in insect cells using a baculovirus vector. The Mr of the recombinant protein estimated by SDS-PAGE was slightly lower than that of the native viral protein. The recombinant protein displayed different degrees of glycosylation and was recognized in ELISA by neutralizing antibodies. It was transported to the plasma membrane of insect cells where its ability to induce membrane fusion was preserved. The efficacy of the recombinant protein as a vaccine was compared with those of an inactivated and an attenuated vaccine. When injected intraperitoneally into rainbow trout, the baculo-virus-encoded protein was shown (i) to induce the synthesis of VHSV-neutralizing antibodies and (ii) to confer protection against virus challenge. Immunization performed by immersion failed. This is the first report of a recombinant vaccine that protects fish against VHSV. [less ▲]

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See detailPlasmids for heavy metal resistance in Alcaligenes eutrophus CH34: Mechanisms and applications
Collard, Jean-Marc; Corbisier, Philippe; Diels, Ludo et al

in FEMS Microbiology Reviews (1994), 14

Alcaligenes eutrophus CH34 is the main representative of a group of strongly related strains (mostly facultative chemolithotrophs) that are well adapted to environments containing high levels of heavy ... [more ▼]

Alcaligenes eutrophus CH34 is the main representative of a group of strongly related strains (mostly facultative chemolithotrophs) that are well adapted to environments containing high levels of heavy metals. It harbors the megaplasmids pMOL28 and pMOL30 which carry resistance determinants to Co2+, Ni2+, CrO42-, Hg2+, Tl+, Cd2+, Cu2+ and Zn2+. Among the best characterized determinants are the cnr operon (resistance to Co, Ni) an pMOL28 and the czc operon on pMOL30 (resistance to Co, Cd and Zn). Although the two systems reveal a significant degree of amino acid similarity in the structural genes, the regulation of the operons is different. The resistance mechanism in both cases is based on efflux. The efflux mechanism leads to a pH increase outside of the cytoplasmic membrane. Metals are sequestered from the external medium through the bioprecipitation of metal carbonates formed in the saturated zone around the cell. This latter phenomenon can be exploited in bioreactors designed to remove metals from effluents. The bacteria are immobilized on composite membranes in a continuous tubular membrane reactor (CTMR). The effluent continuously circulates through the intertubular space, while the external surface of the tubes is in contact with the growth medium. Metal crystals are eventually removed by the effluent stream and collected on a glass bead column. The system has been applied to effluents containing Cd, Zn, Co, Ni and Cu. By introducing catabolic plasmids involved in the aerobic degradation of PCBs and 2,4-D into metal-resistant A. eutrophus strains, the application range was widened to include effluents polluted with both organic and inorganic substances. Biosensors have been developed which are based on the fusion of genes induced by metals to a reporter system, the lux operon of Vibrio fischeri. Bacterial luciferases produce light through the oxidation of fatty aldehydes. The gene fusions are useful both for the study of regulatory genes and for the determination of heavy metal concentrations in the environment. [less ▲]

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See detailA comparative study of reporter gene activities in fish cells and embryos
Sekkali, B.; Hellemans, B.; Belayew, A. et al

in Molecular Marine Biology and Biotechnology (1994), 3

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See detailCell localization and redistribution of the 67 kD laminin receptor and alpha 6 beta 1 integrin subunits in response to laminin stimulation: an immunogold electron microscopy study.
Romanov, V.; Sobel, M. E.; pinto da Silva, P. et al

in Cell Adhesion and Communication (1994), 2(3), 201-9

The 67 kDa laminin receptor (67LR), one of several cell surface laminin-binding proteins, is involved in the interactions between cancer cells and laminin during tumor invasion and metastasis. A 37 kDa ... [more ▼]

The 67 kDa laminin receptor (67LR), one of several cell surface laminin-binding proteins, is involved in the interactions between cancer cells and laminin during tumor invasion and metastasis. A 37 kDa polypeptide (37LRP), previously identified as the 67LR precursor, is abundantly present in the cytoplasm and has been implicated in polysome formation. To better understand the cellular localization of the 67LR and its precursor, transmission electron microscopic studies of human melanoma A2058 cells were carried out using immunogold labeling and a variety of antibodies: (a) affinity purified antibodies directed against 37LRP cDNA-derived synthetic peptides; (b) anti-67LR monoclonal antibodies raised against intact human small cell lung carcinoma cells; and (c) monoclonal antibodies against the subunits of the integrin laminin receptor, alpha 6 beta 1. Double-labeling immunocyto-chemistry revealed that anti-67LR monoclonal antibodies as well as anti-37 LRP antibodies recognized antigens that were localized in the cytoplasm in electron dense structures. As expected, cell membrane labeling was also observed. Surprisingly, alpha 6 and beta 1 integrin subunits were detected in the same cytoplasmic structures positive for the 67LR and the 37LRP. After addition of soluble laminin to A2058 cells in suspension, the number of labeled cytoplasmic structures increased especially in the vicinity of the plasma membrane, and were exported onto the cell surface. Neither fibronectin nor BSA induced such an effect. The data demonstrate that the 67 LR and the 37 LRP antibodies detect colocalized antigens that are in cytoplasmic structures with alpha 6 beta 1 integrin.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailL'agrégé nouveau est arrivé !
Jadoulle, Jean-Louis ULg

in Bulletin de Clio (1994)

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See detailA fuzzy approach to the definition of standardized visibility in fog.
Boreux, Jean-Jacques ULg; Duckstein, Lucien

in Applied Mathematics and Computation (1994), 61(2-3), 287-299

The problem of defining the physical concept of standardized visibility is addressed by means of a fuzzy logic approach. Assuming that several hypotheses hold, it is possible to evaluate a standardized ... [more ▼]

The problem of defining the physical concept of standardized visibility is addressed by means of a fuzzy logic approach. Assuming that several hypotheses hold, it is possible to evaluate a standardized visibility Vk (or meteorological visual range) as the ratio of a psychometric coefficient k and the extinction coefficient σ of the aerosol. The main disadvantage of this relationship due to Koschmieder stems from the fact that the meteorological visual range can be very different from visibility estimated by a human observer with normal sight. This is particularly true during fog extinction coefficient supplied by a transmissometer and the corresponding visibility evaluated by an expert. Calculations are performed according to two different approaches. First, a so-called fuzzy hyperbolic model based on a distance defined by Bardossy et al is presented, yielding a crisp (nonfuzzy) value of the coefficient k. Next, we use the multiplication of two fuzzy numbers, taken as triangular, to build an average fuzzy number k that accounts for the different values found in the literature. The defuzzification of k confirms the result obtained by the first approach. [less ▲]

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See detailSynthesis and pharmacology of pyrid-3-yl sulfonylureas and thioureas as astrocytic Na+ 2Cl- K+ cotransporter inhibitors
Masereel, B.; Renard, P.; Pirotte, Bernard ULg et al

in European Journal of Medicinal Chemistry (1994), 29

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See detailThird Catalogue of stars measured in the Long-Term Photometry of Variables project.
Manfroid, Jean ULg; Sterken, C.; Cunow, B. et al

in European Southern Observatory Scientific Report (1994), 14

Not Available

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See detailGenetic diversity among some wild populations of lima bean (Phaseolus lunatus L.) proceeding from Central Valley of Costa Rica
Maquet, Alain; Wathelet, Bernard ULg; Dubois, Sophie et al

in Annual Report of the Bean Improvment Cooperative (1994)

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See detailCloning And Characterization Of Mn, A Human Tumor-Associated Protein With A Domain Homologous To Carbonic-Anhydrase And A Putative Helix-Loop-Helix Dna-Binding Segment
Pastorek, J.; Pastorekova, S.; Callebaut, I. et al

in Oncogene (1994), 9(10),

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See detailEvaluation of Matrix Metalloproteinases and Serine Proteases Activities in Three B16 Melanoma Cell Lines with Distinct Tumorigenic Potential
Baramova, E. N.; Coucke, P.; Leprince, Pierre ULg et al

in Anticancer Research (1994), 14(3A, May-Jun), 841-6

Mouse B16 melanoma cells (B16, parental line) and two derived clones either pigmented (B16P) or non pigmented (B16NP) were cultured as monolayers (2D) or on agar, as aggregates (3D). The productions of ... [more ▼]

Mouse B16 melanoma cells (B16, parental line) and two derived clones either pigmented (B16P) or non pigmented (B16NP) were cultured as monolayers (2D) or on agar, as aggregates (3D). The productions of gelatinases A and B (72 kDa and 92 kDa type IV collagenases) and their inhibitors (TIMP1 and TIMP2), plasminogen activators (PAs) and plasminogen activator inhibitors (PAI) were investigated. The B16 cell lines did not secrete any gelatinase, but they secreted TIMP2, tissue-type (t-PA), urokinase-type (u-PA) plasminogen activators and PAI-1 like activities. High levels of PAI activity were determined in conditioned media and cellular extracts of B16NP, which could account for the lower tumorigenic potential of these cells. In 3D cultures, the cellular extracts of the three cell lines contained essentially u-PA activity. This activity could contribute to the greater tumorigenic and invasive capacities of B16, B16P and B16NP when cultured in 3D. [less ▲]

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See detailFollicular dendritic cells: whose children?
Heinen, Ernst ULg; Bosseloir, A.

in Immunology Today (1994), 15(5), 201-4

At the recent Germinal Centre Conference in Spa*, over 200 immunologists gathered to study the fate of lymph follicles, B- and T-cell selection, cell migration, accessory cells, and pathological ... [more ▼]

At the recent Germinal Centre Conference in Spa*, over 200 immunologists gathered to study the fate of lymph follicles, B- and T-cell selection, cell migration, accessory cells, and pathological conditions such as lymphoproliferative diseases and AIDS. Here, Ernst Heinen and Alain Bosseloir report on this fascinating field. [less ▲]

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See detailThe treatment of amiodarone-induced hyperthyroidism. Is there a place for surgery?
Meurisse, Michel ULg; Detroz, Bernard ULg; Messens, D. et al

in Acta Chirurgica Belgica (1994), 94(1), 36-41

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced ... [more ▼]

In many instances amiodarone-induced hyperthyroidism has been reported as mild, thyroid functions returning to normal after discontinuation of the drug. Nevertheless, life-threatening amiodarone-induced thyrotoxicosis has also been described. Conventional treatments such as with antithyroid drugs (Thionamide) and corticosteroids are essentially ineffective or fail to stop the dramatic course of the thyroid crisis. This limited efficacy of medical therapy, particularly in patients with previously--neglected or unknown--thyroid disease, prompted us to intervene surgically. We report a series of six patients who underwent total or nearly total thyroidectomy as first line therapy for four of them. Surgery resulted in rapid resolution of thyrotoxicosis with an uneventful postoperative course. This approach has the advantage of immediate and safe efficacy, low risk of relapse and finally, appears to be the only antithyroid treatment that permits continued therapy with amiodarone. [less ▲]

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See detailPhylogenetic relationships among filamentous helical cyanobacteria investigated on the basis of 16S ribosomal RNA gene sequence analysis
Nelissen, Bart; Wilmotte, Annick ULg; Neefs, Jean-Marc et al

in Systematic & Applied Microbiology (1994), 17

The cyanobacterial genera Spirulina and Arthrospira are both characterized by helical trichomes but their taxonomy is controversial and a phylogenetic study is necessary. The sequence of the 16S rRNA gene ... [more ▼]

The cyanobacterial genera Spirulina and Arthrospira are both characterized by helical trichomes but their taxonomy is controversial and a phylogenetic study is necessary. The sequence of the 16S rRNA gene and the spacer between the 16S and 23S rRNA genes (ITS) was determined for three filamentous coiled cyanobacteria: Spirulina PCC 6313, Arthrospira PCC 7345 and Arthrospira PCC 8005. A distance tree based on the 16S rRNA sequences was constructed using the neighbor-joining method. This tree shows that the two Arthrospira strains are not closely related to the Spirulina strain but belong to a cluster of strains assigned to the genera Oscillatoria, Lyngbya, and Microcoleus. The strain Spirulina PCC 6313 belongs to a branching containing unicellular cyanobacteria. For the two Arthrospira strains, the sequenced ITS region contains the tRNA(Ile) and tRNA(Ala) genes, whereas the spacer region of strain Spirulina PCC 6313 contains only the tRNA(Ile) gene. [less ▲]

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See detailCrystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide
Merritt, E. A.; Sarfaty, S.; van den Akker, F. et al

in Protein Science : A Publication of the Protein Society (1994), 3(2), 166-75

Cholera toxin (CT) is an AB5 hexameric protein responsible for the symptoms produced by Vibrio cholerae infection. In the first step of cell intoxication, the B-pentamer of the toxin binds specifically to ... [more ▼]

Cholera toxin (CT) is an AB5 hexameric protein responsible for the symptoms produced by Vibrio cholerae infection. In the first step of cell intoxication, the B-pentamer of the toxin binds specifically to the branched pentasaccharide moiety of ganglioside GM1 on the surface of target human intestinal epithelial cells. We present here the crystal structure of the cholera toxin B-pentamer complexed with the GM1 pentasaccharide. Each receptor binding site on the toxin is found to lie primarily within a single B-subunit, with a single solvent-mediated hydrogen bond from residue Gly 33 of an adjacent subunit. The large majority of interactions between the receptor and the toxin involve the 2 terminal sugars of GM1, galactose and sialic acid, with a smaller contribution from the N-acetyl galactosamine residue. The binding of GM1 to cholera toxin thus resembles a 2-fingered grip: the Gal(beta 1-3)GalNAc moiety representing the "forefinger" and the sialic acid representing the "thumb." The residues forming the binding site are conserved between cholera toxin and the homologous heat-labile enterotoxin from Escherichia coli, with the sole exception of His 13. Some reported differences in the binding affinity of the 2 toxins for gangliosides other than GM1 may be rationalized by sequence differences at this residue. The CTB5:GM1 pentasaccharide complex described here provides a detailed view of a protein:ganglioside specific binding interaction, and as such is of interest not only for understanding cholera pathogenesis and for the design of drugs and development of vaccines but also for modeling other protein:ganglioside interactions such as those involved in GM1-mediated signal transduction. [less ▲]

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See detailGalectins: a family of animal beta-galactoside-binding lectins.
Barondes, S. H.; Castronovo, Vincenzo ULg; Cooper, D. N. et al

in Cell (1994), 76(4), 597-8

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See detailLe Paléolithique supérieur de Moldavie. Recherches récentes
Noiret, Pierre ULg; López Bayón, Ignacio

in Bulletin de l'Association scientifique liégeoise pour la Recherche archéologique (1994), XXI

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See detailAnalysis of the penA gene of Pseudomonas cepacia 249.
Joris, Bernard ULg; Galleni, Moreno ULg; Frère, Jean-Marie ULg et al

in Antimicrobial Agents and Chemotherapy (1994), 38(2), 407-8

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See detailAgglomérations morphologiques et fonctionnelles, l’apport de la télédétection urbaine
Donnay, Jean-Paul ULg

in Acta Geographica Lovaniensia (1994), 34

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See detailChromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers
Cockett, N. E.; Jackson, S. P.; Shay, T. D. et al

in Proceedings of the National Academy of Sciences of the United States of America (1994), 91

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal ... [more ▼]

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal dominant gene may be responsible for this economically advantageous trait. We have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locus to ovine chromosome 18 using a battery of bovine chromosome 21 markers. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene. [less ▲]

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See detailDinant/Anseremme: Trou Magrite
Noiret, Pierre ULg

in Chronique de l'Archéologie wallonne (1994), 2

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See detailRobotique pédagogique, d'un colloque à l'autre : vers l'émergence d'une communauté scientifique ?
Denis, Brigitte ULg; Baron, G. L.

in Sciences et Techniques Educatives [= STE] (1994), 1

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See detailHIGH-RESOLUTION SPECTRA OF JUPITER NORTHERN AURORAL ULTRAVIOLET EMISSION WITH THE HUBBLE-SPACE-TELESCOPE
TRAFTON, L. M.; Gérard, Jean-Claude ULg; Munhoven, Guy ULg et al

in Astrophysical Journal (1994), 421(2), 816-827

The first spectroscopic observations of planetary aurora with the HST are reported. These include spectral regions centered on the H-2 Lyman and Werner bands of a region of Jupiter's northern aurora. The ... [more ▼]

The first spectroscopic observations of planetary aurora with the HST are reported. These include spectral regions centered on the H-2 Lyman and Werner bands of a region of Jupiter's northern aurora. The observations were made with the Goddard High Resolution Spectrograph (GHRS) using the Large Science Aperture as part of a campaign to study Jupiter at the time of the Ulysses flyby. The individual rotational-vibrational bands are resolved and the observed emissions are essentially all from H-2. A rotational-vibrational temperature for H-2 of 530 +/- 100 K is derived, a value significantly less than the 850-1100 K reported for Jovian H-3(+) in the near-infrared but consistent with the temperature reported for fundamental-band quadrupole H-2 emission. Comparison with the Faint Object Camera (FOC) images shows that the observed region was not one of the hot spots of the aurora. The results are interpreted in terms of electron impact excitation of H-2 from secondary particles generated by primaries precipitating into Jupiter's atmosphere from the magnetosphere. In the region of the aurora observed, the homopause level is found to be significantly hotter but not necessarily higher than observed at nonauroral latitudes. The equatorial H-2 dayglow spectrum was also detected; its intensity was 3.2 kR or 13% of the strength of the observed auroral emission. [less ▲]

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See detailSecteur public contre secteur privé : l'Etat de l'opinion en Wallonie
Jacquemain, Marc ULg; Doutrelepont, René; Vandekeere, Michel

in Recherches Sociologiques et Anthropologiques (1994), 25-1

Through survey results, the paper shows what fields of activity should be managed either by the public sector or by the private sector according to the opinion of the Walloons. It also shows how the ... [more ▼]

Through survey results, the paper shows what fields of activity should be managed either by the public sector or by the private sector according to the opinion of the Walloons. It also shows how the balance changes according to certain characteristics of the population [less ▲]

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See detailRedox Mechanism For The Chaperone Activity Of Heat-Shock Proteins Hsp-60, Hsp-70 And Hsp-90 As Suggested By Hydrophobic Cluster-Analysis - Hypothesis
Callebaut, I.; Catelli, Mg.; Portetelle, Daniel ULg et al

in Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1994), 317(8),

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See detailB.E.M.S. : Batterie d'Evaluation de la Morpho-Syntaxe : développement, évaluation, et lignes d'action
Fayasse, M.; Comblain, Annick ULg; Rondal, Jean-Adolphe ULg

in Informations pédagogiques (1994), 12

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See detailLe Monitoring de la pression artérielle en pratique médicale : apports et limites
Saint-Remy, Annie ULg; Rorive, Georges ULg

in Blood Pressure Profil (1994), 3

"L'article de Mme Saint-Remy et de G. Rorive constitue une bonne mise au point sur les controverses qui continuent à se développer autour de la place à réserver au monitorage ambulatoire de la pression ... [more ▼]

"L'article de Mme Saint-Remy et de G. Rorive constitue une bonne mise au point sur les controverses qui continuent à se développer autour de la place à réserver au monitorage ambulatoire de la pression artérielle (MAPA) dans l'évaluation du patient hypertendu. La variabilité importante universellement admise de la pression artérielle rend le concept du monitorage pendant 24 heures particulièrement attrayant. L'utilité de cette nouvelle approche ne sera cependant définitivement établie que quand les résultats d'études prospectives visant à démontrer la supériorité du MAPA sur la mesure conventionnelle de la pression artérielle seront connus. Deux études sont au minimum actuellement en cours en ce sens : l'étude OVA et l'étude Systeur. En attendant, le manque de valeurs normatives est évidemment un handicap pour l'intérêt de la MAPA dans la pratique journalière et ce d'autant plus que le coût de cette nouvelle méthodologie reste élevé. Dans la revue de la littérature de ce numéro de Blood Pressure Profile, deux publications viennent confirmer ce qui est avancé dans l'article de Mme Saint-Remy. Bianchi et col, observant que la microalbuminurie est plus importante chez les hypertendus en l'absence de chute nocturne de la pression artérielle, argumentent en faveur du rôle de la MAPA dans l'évaluation du pronostic cardio-vasculaire du patient hypertendu. De plus, Mansoor et al, confirmant la meilleure reproductibilité de MAPA par rapport à la mesure conventionnelle de la pression artérielle, concluent également que la MAPA permettra de diminuer le nombre de patients à inclure dans des essais de pharmacologie clinique. Ces résultats, bien qu'encourageant pour les défenseurs du MAPA, ne doivent cependant pas nous faire oublier que la généralisation de l'utilisation de cette nouvelle technique est à l'heure actuelle prématurée" Prof. J.P. Degaute, Hypertension Clinic, Hôpital Universitaire Erasme, Chief Editor [less ▲]

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See detailComplete Dna-Sequence Of Yeast Chromosome-Xi
Dujon, Bernard; Esteban, Pf.; Fernandes, L. et al

in Nature (1994), 369(6479),

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See detailEpidemiology of insulin resistance and hypertension in adults - MONICA BELLUX- preliminary results.
Saint-Remy, Annie ULg; Beck, Dominique; Lefèbvre, Pierre ULg et al

in Cardiovascular Disease Epidemiology Newsletter, Amercian Heart Association (1994), 49

Numerous publications have outlined that insulin resistance, hypertension and obesity are often associated suggesting a common link in the pathogenic mechanisms.

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See detailL'enseignement du français instrumental à l'université: quelles possibilités?
Vanden Berghe, Kristine ULg; Sanctobin, Véronique; Slootmaekers, An et al

in Rencontres (1994), 5

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See detail3D turbulence field on the north-western european continental-shelf
Martin, Géraldine ULg; Delhez, Eric ULg

in Tellus : Series A (1994), 46(2), 98-112

The 3-dimensional, non-linear, baroclinic, GHER mathematical model for the study of mesoscale motions (time scale of several hours to several days: tides, storm surges, ...) is described. Particular ... [more ▼]

The 3-dimensional, non-linear, baroclinic, GHER mathematical model for the study of mesoscale motions (time scale of several hours to several days: tides, storm surges, ...) is described. Particular attention is paid to the turbulent closure based on an evolution equation for the turbulent kinetic energy and a parametric expression of the mixing length (k-model). Appropriate boundary conditions and numerical techniques (mode-splitting, implicity, sigma-coordinate system, advection scheme) are described. The model is applied to the simulation of the M2 tide on the North-Western European Continental Shelf not only without wind but also in typical winter and summer conditions. Large spatial variations of the turbulent kinetic energy appear as a result of the variations of depth and tidal activity around the shelf. These variations are clearly related to the different turbulence regimes observed in summer, with frontal structures separating well-mixed waters from stratified ones. The structure and evolution of the vertical profiles of turbulence variables are described and explained in barotropic and baroclinic conditions, under different wind forcings. The evolution of these profiles at the M2 tide frequency largely depends on the eccentricity of the tidal ellipse. [less ▲]

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See detailAn isozyme study in Bilberry (Vaccinium myrtillus ) 2. Mating system and genetic structure
Jacquemart, Anne Laure; Mahy, Grégory ULg; Raspé, Olivier et al

in Belgian Journal of Botany (1994), 127

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See detailMarqueurs tumoraux
Charlier, Corinne ULg; Plomteux, Guy ULg

in Focus Diagnostica (1994), 2

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See detailEffet du chargement et de la période de complémentation au pâturage sur les performances de taurillons finis en stabulation
Dufrasne, Isabelle ULg; Gielen, Marc ULg; Limbourg, Pierre et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailInactivation of alpha(2)-Macroglobulin by Activated Human Polymorphonuclear Leukocytes.
Deby, Ginette ULg; Croisier, Jean-Louis ULg; Camus, Gérard et al

in Mediators of Inflammation (1994), 3(2), 117-23

The proteolytic activity of trypsin releases the dye Remazol Brilliant Blue from its high molecular weight substrate, the skin powder (Hide Powder Azure, Sigma), with an increase in absorbance at 595 nm ... [more ▼]

The proteolytic activity of trypsin releases the dye Remazol Brilliant Blue from its high molecular weight substrate, the skin powder (Hide Powder Azure, Sigma), with an increase in absorbance at 595 nm. Active alpha(2)- macroglobulin (80 mug/ml) totally inhibits the proteolytic activity of trypsin (14 mug/ml) by trapping this protease. But after a 20 min incubation of alpha(2)-macroglobulin at 37 degrees C with 2 x 10(6) human polymorphonuclear leukocytes activated by N-formyl-L-methionyl-L-leucyl-L-phenylalanine (10(-7) M) and cytochalasin B (10(-8) M), 100% of trypsin activity was recovered, indicating a total inactivation of alpha(2)-macroglobuHn. Incubation with granulocyte myeloperoxidase also inactivates alpha(2)-macroglobulin. Hypochlorous acid, a by-product of myeloperoxidase activity, at a concentration of 10(-7) M also inactivates alpha(2)-macroglobulin, which indicates that an important cause of alpha(2)-macroglobulin inactivation by activated polymorphonuclear leukocytes could be the activity of myeloperoxidase. [less ▲]

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See detailA semiautomated test apparatus for studying partner preference behavior in the rat.
Bakker, Julie ULg; van Ophemert, J.; Eijskoot, F. et al

in Physiology & Behavior (1994), 56(3), 597-601

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the ... [more ▼]

A semiautomated three-compartment box (3CB) for studying partner preference behavior of rats is described. This apparatus automatically records the rat's time spent in each compartment, as well as the locomotor activity (i.e., the number of visits an animal pays to each compartment). Software was developed for calculating partner preference scores. Behavioral testing in the semiautomated 3CB, which is a modification of an earlier version, is less time consuming and less laborious. Three 3CBs can be observed simultaneously by two trained observers, and the behavioral interactions of three experimental animals with the stimulus animals can be observed and scored by hand. The use of the new apparatus was validated by studying adult partner preference behavior of neonatally ATD-treated male rats. The collected data fully corroborate previous results, obtained in the earlier version of the 3CB, again revealing the behavioral bisexual nature of these ATD males. A new finding was the much higher locomotor activity of the ATD males compared to controls. [less ▲]

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See detailThe experience of radical prostatectomy for locally confined prostate cancer in Liege.
Bouffioux, Christian ULg; de Leval, Jean ULg; Andrianne, Robert ULg et al

in Acta Urologica Belgica (1994), 62(1), 51-9

The authors report their experience of 148 radical prostatectomies performed for adeno-carcinoma. They expose the reasons which have led them to adopt this kind of treatment and the reasons explaining a ... [more ▼]

The authors report their experience of 148 radical prostatectomies performed for adeno-carcinoma. They expose the reasons which have led them to adopt this kind of treatment and the reasons explaining a nearly exponential increase of the frequency of the operation during the last 5 years. They underline the importance of lymphadenectomy and the safety of frozen sections of the nodes. The surgical technique is briefly commented and the (low) morbidity of the operation is reviewed. They compare the results of RPV to those of external radiotherapy, watchful attitude or immediate hormonal treatment and they conclude in insisting on the benefit of the surgical approach as far as indications (which are defined) are strictly followed. [less ▲]

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See detailStereoselective syntheses of cyclopropane derivatives from γ-alkoxy-α,β-unsaturated carbonyl compounds and methylene transfer reagents
Krief, Alain; Dumont, Willy; Lecomte, Philippe ULg

in Polish Journal of Chemistry (1994), 68

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See detailThe Dissociative Electroionization of C2H2, C2D2 and C2HD. Investigation of the [C2H(D)]+ and [H(D)]+ Dissociation Channels. The (D)H-C2H(D) binding energy.
Davister, M.; Locht, Robert ULg

in Chemical Physics (1994), 189

The dissociative electroionization of C2H2 in the H+ and C2H+ dissociation channels has been extensively investigated in C2H2 and C2D2. The kinetic energy distributions and ionization efficiency curves of ... [more ▼]

The dissociative electroionization of C2H2 in the H+ and C2H+ dissociation channels has been extensively investigated in C2H2 and C2D2. The kinetic energy distributions and ionization efficiency curves of both species were examined in detail. The H(D)+ ion shows its lowest onset energy at 18.93+/-0.2 eV whereas the C2H+ is produced at 17.30+/-0.11 eV. For the H+-producing channel the kinetic energy (KE) versus the appearance energy (AE) diagram is obtained, extensively discussed and the bond dissociation energy D(H-C2H)= 5.33+/-0.23 eV is estimated. This value is compared and discussed with respect to the values found in the literature. Predissociation and dissociative autoionization are the dominant H+-producing mechanisms. At high electron energies doubly ionized states of C2H2 are involved. For C2H+, beside the threshold at 17.30+/0.11 eV a new onset at 18.27+/0.10 eV is observed. The ionization efficiency of the doubly ionized molecular ion is observed for the first time in C2HD isotopic species. [less ▲]

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See detailcerebral blood flow velocities measurements on anterior cerebral artery during general anesthesia and minor surgery
Battisti, Oreste ULg

in Circulation et Métabolisme du Cerveau (1994), 11

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See detailPretreatment minimal staging for non-small cell lung cancer: an updated consensus report
Goldstraw; Rocmansb; Ball et al

in Lung Cancer (1994), 11(supp 3), 1-4

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See detailLe passage à la paternité: une approche clinique
Naziri, Despina ULg; Dragonas, Th.

in Psychiatrie de l'Enfant (La) (1994), 37(2), 601-629

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See detailBon anniversaire. Compte rendu de la Xe Table Ronde ‘Informatique et Égyptologie, Bordeaux, 1994’
Winand, Jean ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1994), 41

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See detailHuman follicular dendritic cells in vitro
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Dendritic Cells (1994), 4

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See detailAnsiedad y rendimiento academico
Egido, A.; Born, Michel ULg; Sineiro, Garcia

in Revista Galega de Psicopedagogia (1994), 9(6), 157-168

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See detailStructure and orientation of apo B-100 peptides into a lipid bilayer.
Lins, Laurence ULg; Brasseur, Robert ULg; Rosseneu, M. et al

in Journal of Protein Chemistry (1994), 13(1), 77-88

Peptides corresponding to lipid binding domains of Apo B-100 were synthesized, purified, and incubated with dimyristoylphosphatidylcholine (DMPC) liposomes. The secondary structure of the apo B-100 ... [more ▼]

Peptides corresponding to lipid binding domains of Apo B-100 were synthesized, purified, and incubated with dimyristoylphosphatidylcholine (DMPC) liposomes. The secondary structure of the apo B-100 peptide-lipid complexes was evaluated by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Those peptides belonging to the hydrophobic "core" domain of apo B-100 when associated with phospholipids were rich in beta sheet structure; a predominant alpha helical conformation was shown to be associated with one peptide located in a surface region of apo B-100. IR dichroic spectra revealed, in the case of the "core" peptides, that the beta sheet component is the only oriented structure with respect to the phospholipid acyl chains. This orientation of the beta sheet was recently found in LDL particles after proteolytic digestion by trypsin (Goormaghtigh, E., Cabiaux, V., De Meutter, J., Rosseneu, M., and Ruysschaert, J. M., 1993, Biochemistry 32, 6104-6110). Altogether, the data suggest that beta sheet, present in a high proportion in the native apo B-100, is probably another protein structure in addition to the amphipathic helix which strongly interacts with the lipid outer layer surrounding the LDL particle. [less ▲]

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See detailLa métropolisation, une nouvelle donne
Merenne-Schoumaker, Bernadette ULg

in Acta Geographica Lovaniensia (1994), (34), 165-174

The recent economic growth of many big cities has led to the new concept of "metropolization" and to numerous research based on new models of urban growth. In trying to draw up on this theme, one has ... [more ▼]

The recent economic growth of many big cities has led to the new concept of "metropolization" and to numerous research based on new models of urban growth. In trying to draw up on this theme, one has tackled successively four points: the concepts of metropolis and metropolization, the metropolization process, the metropolization and the city systems, the metropolization in Europe and Belgium. [less ▲]

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See detailCompte-rendu de l'ouvrage de Chester G. Starr : The Aristocratic Temper of Greek Civilization
Vanhaegendoren, Koen ULg

in Etudes Classiques (1994), 62(1), 92

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See detailPerformances physiques et motrices d’enfants de l’enseignement fondamental engagés ou non dans un programme d’activités physiques quotidiennes
Cloes, Marc ULg; Delfosse, Catherine; Ledent, Maryse et al

in Revue de l'Education Physique (1994), 34(2-3), 59-68

La recherche d'un développement physique et moteur harmonieux et complet figure parmi les objectifs des différentes expériences proposant des activités physiques quotidiennes en milieu scolaire. La ... [more ▼]

La recherche d'un développement physique et moteur harmonieux et complet figure parmi les objectifs des différentes expériences proposant des activités physiques quotidiennes en milieu scolaire. La programmation de séances régulières d'éducation physique semble déboucher sur des niveau de condition physique supérieurs. ... [less ▲]

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See detailExpression and function of DRC-1 antigen.
Bosseloir, A. L.; Antoine, Nadine ULg; Heinen, Ernst ULg et al

in Advances in Experimental Medicine and Biology (1994), 355

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See detailAge-related differences in updating working memory
Van der Linden, Martial ULg; Brédart, Serge ULg; Beerten, A.

in British Journal of Psychology (1994), 85(1), 145-152

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See detailMicroencapsulation by Coacervation of Poly(lactide-co-glycolide). III. Characterization of the Final Microspheres
Nihant, Nicole; Stassen, Sophie; Grandfils, Christian ULg et al

in Polymer International (1994), 34

This paper deals with protein microencapsulation by coacervation of poly(lactide-co-glycolide) solutions in CH2Cl2 induced by the addition of silicone oils of various viscosities. This coating technique ... [more ▼]

This paper deals with protein microencapsulation by coacervation of poly(lactide-co-glycolide) solutions in CH2Cl2 induced by the addition of silicone oils of various viscosities. This coating technique proceeds along three steps: phase separation of the coating polyester, adsorption of the coacervate droplets around the protein phase, and hardening of microparticules. Size distribution, surface morphology and internal porosity of the final microspheres clearly depend on the main characteristics of the coacervate, particularly the viscosity, in a direct connection with the CH2Cl2 content. Indeed, the whole porosity (which may be as high as 80%), average pore size and broadness of pore size distribution decrease as the coacervate is more viscous. Hardening of the coacervate droplets is thus so fast that the organic solvent is entrapped within the polymer matrix and predetermines the internal porosity. Finally, size distribution of microspheres is bimodal in a clear relation with the coacervate viscosity. A less viscous coacervate favours smaller microspheres (within the 7-90 µm range), contaminated with a minor population of microparticles below 4 µm. [less ▲]

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See detailArt et technique
Duchesne, Jean-Patrick ULg

in Art&fact (1994), 13

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See detail"Des biet ou lombardeau": La langue d'un écrivant belgoroman du début du 17e siècle
Boutier, Marie-Guy ULg; Chambon, Jean-Pierre

in Revue de Linguistique Romane (1994), 58

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See detailTHERMAL-CONDUCTIVITY OF PURE OR IRON-DOPED YBA2CU3O7-DELTA WITH OR WITHOUT AN EXCESS OF CUO
Houssa, M.; Bougrine, Hassan ULg; Ausloos, Marcel ULg et al

in Journal of Physics : Condensed Matter (1994), 6(31), 6305-6316

The thermal conductivities of YBa2(Cu1-xFex)3O7-delta + y% CuO ceramics for 0 < x < 0.03 and 0 < y < 5 have been measured. The thermal conductivities of all samples exhibit a minimum in the vicinity of ... [more ▼]

The thermal conductivities of YBa2(Cu1-xFex)3O7-delta + y% CuO ceramics for 0 < x < 0.03 and 0 < y < 5 have been measured. The thermal conductivities of all samples exhibit a minimum in the vicinity of the critical temperature T(c) and a maximum near T(c)/2. These results are interpreted with the help of an electronic model, i.e. supposing that the main contribution to the thermal conductivity below T(c) is due to electron scattering in the CuO2 planes. Within a simple two-fluid model derived from kinetic theory, taking into account the temperature dependence of the electronic relaxation time and the normal charge carrier concentration, we obtain theoretical curves which reproduce the experimental results quite well. We also take into account the porosity of the samples (in term of an intergrain contribution) to derive the electronic thermal conductivity. The parameter values of the model and the observed minimum are explained in terms of physical properties. In particular, the contribution of superconductivity fluctuations to the thermal conductivity is shown to be negligible with respect to other mechanisms. [less ▲]

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See detailNescio als 'Animal Metaphysicum'
Yans, Baudoin ULg

in Spiegel der Letteren (1994), (1), 45-62

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See detailAutonomously functioning thyroid nodules in a patient with a thyrotropin-secreting pituitary adenoma: possible cause--effect relationship.
Abs, R.; Stevenaert, Achille ULg; Beckers, Albert ULg

in European Journal of Endocrinology (1994), 131(4), 355-8

A 51-year-old female patient with long-standing hyperthyroidism due to a thyrotropin-secreting pituitary adenoma is reported, who became thyrotoxic again shortly after successful pituitary surgery ... [more ▼]

A 51-year-old female patient with long-standing hyperthyroidism due to a thyrotropin-secreting pituitary adenoma is reported, who became thyrotoxic again shortly after successful pituitary surgery. Functional testing and scintigraphy suggested the diagnosis of autonomous functioning thyroid nodules, which was confirmed by pathological examination of the resected thyroid tissue. This is the first report revealing the transition from a pituitary-dependent to a thyroid-dependent hyperthyroidism. Autonomous functioning thyroid nodules are, however, considered an intrinsic thyroid defect. In similarity with other disorders, in which trophic hormones may induce an autonomous secretion by the target gland, this report opens the possibility that a humoral factor may play a role in the development of autonomous functioning thyroid nodules. [less ▲]

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See detailThe coupling of quark and gluon condensates in hot and dense systems
Jaminon, Martine ULg; Van den Bossche, Bruno

in Nuclear Physics A (1994), 567

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See detailLes enseignants dans l’expérience pédagogique d’éducation physique quotidienne en Communauté Française de Belgique. Perceptions et réactions
Delfosse, Catherine; Cloes, Marc ULg; Ledent, Maryse et al

in Revue de l'Education Physique (1994), 34(2-3), 89-98

Même dans une démarche pédagogique centrée sur l'enfant, l'enseignant reste le principal décideur. C'est lui qui sélectionne le contenu qu'il considère le plus adéquat aux habiletés et qualités de l ... [more ▼]

Même dans une démarche pédagogique centrée sur l'enfant, l'enseignant reste le principal décideur. C'est lui qui sélectionne le contenu qu'il considère le plus adéquat aux habiletés et qualités de l'enfant, choisir les formes d'organisation, dirige l'interaction en classe et veille à l'établissement du climat de travail le plus favorables à l'épanouissement de l'élève. ... [less ▲]

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See detailConformal invariance and degrees of freedom in the QCD string
Dienes, Keith R; Cudell, Jean-René ULg

in Physical Review Letters (1994), 72

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See detailUniversal scaling laws and the QCD scale anomaly
Ripka, Georges; Jaminon, Martine ULg

in Physics Reports (1994), 242

An effective chiral Lagrangian is given which implements the QCD scale anomaly and the universal scaling law of hadron masses. It is used to study the pion mass and the coupling between quark and gluon ... [more ▼]

An effective chiral Lagrangian is given which implements the QCD scale anomaly and the universal scaling law of hadron masses. It is used to study the pion mass and the coupling between quark and gluon condensates in dense matter. [less ▲]

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See detailSelective Antiprotozoal Activity of Some Strychnos Alkaloids
Wright, Colin; Allen, David; Cai, Ya et al

in Phytotherapy Research (1994), 8

The in vitro activities of 28 Strychnos alkaloids have been determined against three species of protozoa and the most active compounds were then assessed for in vitro cytotoxic activity against KB cells ... [more ▼]

The in vitro activities of 28 Strychnos alkaloids have been determined against three species of protozoa and the most active compounds were then assessed for in vitro cytotoxic activity against KB cells. 3',4'-dihydrousambarensine was the most active against Plasmodium falciparum and was relatively nontoxic to KB cells (cytotoxic/antiplasmodial ratio, 1474). Usambarensine displayed the most selectivity against Entamoeba histolytica while "',4'-dihydrousambarensine was the most selective compound against Giardia intestinalis although the cytotoxic/antiprotozoal ratios (20.4 and 6.6 respectively) were less favourable than the above.The four strychnobiline-type alkaloids were found devoid of activity against E. histolytica and G. intestinalis but to have weak antiplasmodial properties (7-13 times less active than chloroquine). None of the compounds containing only one indole ring system displayed antiprotozoal properties. [less ▲]

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See detailHow to improve the working conditions with an aerosol delivery equipment suitable for calves ?
Genicot, B.; Peckova, M.; Lamberty, S. et al

in American Journal of Respiratory & Critical Care Medicine (1994), 149

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See detailNeuropeptides cutanés
Tassoudji, Nazli ULg; Nikkels, Arjen ULg; Pierard, Gérald ULg

in Les Nouvelles Dermatologiques (1994), 13

The neuropeptides act as mediators in the transmission of nervous influx and as messengers between the nervous system and other cell populations. The skin contains numerous neuropeptides which are ... [more ▼]

The neuropeptides act as mediators in the transmission of nervous influx and as messengers between the nervous system and other cell populations. The skin contains numerous neuropeptides which are involved in the regulation of inflammation, immunomodulation, and thermoregulation. Cutaneous trophicity, pigmentation, and to a lesser extent sebaccous secretions are also influenced by neuropeptides. This review describes the functions of the most important neuropeptides encountered at the level of the skin. [less ▲]

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See detailA REMARKABLE AURORAL EVENT ON JUPITER OBSERVED IN THE ULTRAVIOLET WITH THE HUBBLE-SPACE-TELESCOPE
Gérard, Jean-Claude ULg; Grodent, Denis ULg; Prangé, R. et al

in Science (1994), 266(5191), 1675-1678

Two sets of ultraviolet images of the Jovian north aurora were obtained with the Faint Object Camera on board the Hubble Space Telescope. The first series shows an intense discrete are in near corotation ... [more ▼]

Two sets of ultraviolet images of the Jovian north aurora were obtained with the Faint Object Camera on board the Hubble Space Telescope. The first series shows an intense discrete are in near corotation with the planet. The maximum apparent molecular hydrogen emission rate corresponds to an electron precipitation of similar to 1 watt per square meter, which is about 30,000 times larger than the solar heating by extreme ultraviolet radiation. Such a particle heating rate of the auroral upper atmosphere of Jupiter should cause a large transient temperature increase and generate strong thermospheric winds. Twenty hours after initial observation, the discrete are had decreased in brightness by more than one order of magnitude. The time scale and magnitude of the change in the ultraviolet aurora leads us to suggest that the discrete Jovian auroral precipitation is related to large-scale variations in the current system, as is the case for Earth's discrete aurorae. [less ▲]

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See detailSpecific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA.
Laptev, A. V.; Lu, Z.; Colige, Alain ULg et al

in Biochemistry (1994), 33(36), 11033-9

A series of antisense oligonucleotides (ASOs) were synthesized and tested to define the best target sites within an RNA transcript of collagen for effective inhibition of expression. The test system ... [more ▼]

A series of antisense oligonucleotides (ASOs) were synthesized and tested to define the best target sites within an RNA transcript of collagen for effective inhibition of expression. The test system consisted of mouse NIH 3T3 fibroblasts that were stably transfected with a human minigene for procollagen I so that the cells simultaneously synthesized full-length mouse pro alpha 1 (I) chains and internally deleted human pro alpha 1 (I) chains. The sequences of the transcripts from both genes were compared, and a series of 28 ASOs were designed to target sites in which there were at least two base differences within a 20-nucleotide sequence between the human and mouse transcripts. Six of the ASOs specifically decreased the levels of pro alpha 1 (I) chain synthesized from the human gene without a decrease in the levels of pro alpha 1 (I) chains from the mouse endogenous gene. The most effective ASOs reduced the intracellular levels of human pro alpha 1 (I) chains relative to the mouse pro alpha 1 (I) chains to 37-67% of the control values. Combined addition of two effective ASOs or a second administration of the same effective ASO did not produce any additive effect. The results did not support previous suggestions that the best target sites for ASOs were sequences around initiation codons for translation, at intron-exon boundaries, or in single-stranded loops in hairpin structures. Also, the results did not support previous suggestions that the most effective ASOs are those with the highest affinities for their target sequences. Instead, the most consistent pattern in the data was that the most effective ASOs were those targeted to sequences that were predicted to form clustered double-stranded structures in RNA transcripts. [less ▲]

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See detailEtude multicentrique du dosage de la transferrine déficiente en acide sialique par deux techniques chromatographiques
Vernet, M.; Renversez, J. C.; Revenant, M. C. et al

in Annales de Biologie Clinique (1994), 52

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See detailFear reactions of ewes to photographic images
Vandenheede, Marc ULg; Bouissou, Marie-France

in Behavioural Processes (1994), 32

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See detailCLAY SUPPLIES IN THE CENTRAL INDIAN BASIN SINCE THE LATE MIOCENE - CLIMATIC OR TECTONIC CONTROL
Fagel, Nathalie ULg; DEBRABANT, P.; André, Luc

in Marine Geology (1994), 122(1-2), 151-172

Mineralogical (X-ray diffraction, differential thermal analysis), geochemical [microprobe, inductively coupled plasma (ICP)-atomic emission spectrometry, ICP-mass spectrometry] and Sr-Nd isotopic analyses ... [more ▼]

Mineralogical (X-ray diffraction, differential thermal analysis), geochemical [microprobe, inductively coupled plasma (ICP)-atomic emission spectrometry, ICP-mass spectrometry] and Sr-Nd isotopic analyses have been carried out on the clay size fraction of Late Miocene to Pleistocene sediments from the Central Indian Basin. The samples were taken from five giant cores recovered between 1-degree and 10-degrees-S on a transect along 80-degree-E. The clay assemblages are homogeneous and characterized by an alteration of illite- and smectite-rich levels. Most of the clays are detrital and were derived from a unique source: the weathering of the Indo-Gangetic Plain supplied most of the eroded material. Temporal clay mineralogical fluctuations in the depositional basin reflect environmental changes in the provenance. On the basis of spectral analyses of a mineralogical parameter (peak height ratios), the fluctuating smectite-illite clay sedimentation is controlled by periodic Late Miocene climatic changes. During the Late Pliocene, an irregular, probably tectonic, control appeared. [less ▲]

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See detailCréer un programme de formation pour des professionnels de la Petite Enfance en Communauté germanophone de Belgique. Un enjeu pour le développement de la qualité de service.
Pirard, Florence ULg

in La Lettre. Formation. Développement local. L'accueil de la petite enfance: évaluation (1994), 3

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See detailLocalisation scintigraphique de tumeurs neuroendocrines et de leurs métastases par un analogue de la somatostatine: [111In-DTPA-d-phe1] octreotide
Beckers, Albert ULg; Pham, V. T.; Abs, R. et al

in Médecine & Chirurgie Digestives (1994), 23(3), 145-150

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See detailPossessoire, pétitoire, référé, plainte, bornage et revendication ...Quand tout s'emmêle!
Lecocq, Pascale ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1994)

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See detailSubcellular Localization and Compartmentation of Thiamine Derivatives in Rat Brain
Bettendorff, Lucien ULg; Wins, Pierre; Lesourd, Monique

in Biochimica et Biophysica Acta (1994), 1222(1), 1-6

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin ... [more ▼]

The subcellular distribution of thiamine derivatives in rat brain was studied. Thiamine diphosphate content was highest in the mitochondrial and synaptosomal fractions, and lowest in microsomal, myelin and cytosolic fractions. Only 3-5% of total thiamine diphosphate was bound to transketolase, a cytosolic enzyme. Thiamine triphosphate was barely detectable in the microsomal and cytosolic fraction, but synaptosomes were slightly enriched in this compound compared to the crude homogenate. Both myelin and mitochondrial fractions contained significant amounts of thiamine triphosphate. In order to estimate the relative turnover rates of these compounds, the animals received an intraperitoneal injection of either [14C]thiamine or [14C]sulbutiamine (isobutyrylthiamine disulfide) 1 h before decapitation. The specific radioactivities of thiamine compounds found in the brain decreased in the order: thiamine > thiamine triphosphate > thiamine monophosphate > thiamine diphosphate. Incorporation of radioactivity into thiamine triphosphate was more marked with [14C]sulbutiamine than with [14C]thiamine. The highest specific radioactivity of thiamine diphosphate was found in the cytosolic fraction of the brain, though this pool represents less than 10% of total thiamine diphosphate. Cytosolic thiamine diphosphate had a twice higher specific radioactivity when [14C]sulbutiamine was used as precursor compared with thiamine though no significant differences were found in the other cellular compartments. Our results suggest the existence of two thiamine diphosphate pools: the bound cofactor pool is essentially mitochondrial and has a low turnover; a much smaller cytosolic pool (6-7% of total TDP) of high turnover is the likely precursor of thiamine triphosphate. [less ▲]

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See detailTHE BLOOD PROTEINS OF THE ANTARCTIC ICEFISH CHANNICHTHYS-RHINOCERATUS - BIOLOGICAL SIGNIFICANCE AND PURIFICATION OF THE 2 MAIN COMPONENTS
Feller, Georges ULg; Poncin, A.; Aittaleb, M. et al

in Comparative Biochemistry and Physiology. B : Comparative Biochemistry (1994), 109(1), 89-97

The lack of hemoglobin and of carbonic anhydrase in the blood of icefish suggest that substantial adaptations of the acid-base balance should occur in order to ensure blood pH homeostasis. The level of ... [more ▼]

The lack of hemoglobin and of carbonic anhydrase in the blood of icefish suggest that substantial adaptations of the acid-base balance should occur in order to ensure blood pH homeostasis. The level of peptidic histidyl and of reactive -SH groups per unit of body mass in icefish plasma are 12-13 times higher that those of Notothenia rossii, a common red-blooded Antarctic species. It is proposed that the high level of imidazole ring in icefish plasma improves the non-bicarbonate buffering capacity and that the reactive sulfhydryls are involved om a redox buffer as in some other hypoxia tolerant species. After plasma fractionation on Ultrogel AcA 34, the two main icefish serum proteins have been purified by DEAE cellulose chromatography (IFI) and by HPLC on anion exchange column (IF2). IFI has been identified as a cysteine-rich para-albumin and IF2 as an histidine-rich immunoglobulin-like protein. [less ▲]

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See detailSequence-Analysis Of A 40.2-Kb Dna Fragment Located Near The Left Telomere Of Yeast Chromosome-X
Vandenbol, Micheline ULg; Durand, Patrick; Bolle, P. A. et al

in Yeast (1994), 10(12),

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See detailC.R. de La Passion du Palatinus. Mystère du XVe siècle.
Henrard, Nadine ULg

in Lettres Romanes (1994), XLVIII(3-4), 376-377

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See detailOnce-a-day administration of amikacin in neonates: clinical evidence of the validity of a pharmacokinetic according to the gestational age
Battisti, Oreste ULg; Wallemacq P; Langhendries JP

in Early Human Development (1994), 38

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See detailApplied methodology to delineate protection zones around pumping wells
Dassargues, Alain ULg

in Journal of Environmental Hydrology (1994), 2(2), 3-10

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See detailValeurs de référence de la ferritine sérique chez l'adulte
Vernet, M.; Revenant, M. C.; Charlier, Corinne ULg et al

in Annales de Biologie Clinique (1994), 52

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See detailC.R. du Mystère de la Résurrection. (Angers, 1456)
Henrard, Nadine ULg

in Lettres Romanes (1994), XLVIII(1-2), 112-114

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See detailLogiciel d'aide à la détermination détaillée du poids et du bilan électrique d'un navire
Marchal, Jean ULg; Hage, André ULg; Rodriguez, S.

in Bulletin de l'Association Technique Maritime et Aéronautique (1994)

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See detailModélisation mathématique appliquée à la délimitation des zones de protection: cas du site de captage de Vivegnis (plaine alluviale de la Meuse, Belgique)
Derouane, Johan; Dassargues, Alain ULg

in Bulletin du Centre d'Hydrogéologie de l'Université de Neuchätel (Suisse) (1994), 13

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See detailTechnical Study of Some Major Parameters Influencing the Performances of an Aerosol Delivery Equipment Suitable for Calves
Genicot, Bruno; Peckova, M.; Close, Roland et al

in Veterinary Research (1994), 25(5), 468-77

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal ... [more ▼]

Aerosol delivery equipment, suitable for the treatment of bovine respiratory dysfunctions and including 2 parallelly positioned jet nebulizers, was studied in depth in order to determine the optimal working conditions in the field. Indeed, some factors might reasonably alter the performance of this equipment. Among these factors, the influences of the parallel position of jet nebulizers (in order to accommodate the breathing requirements of the cattle and achieve a rapid treatment), of the long feed pipe delivering compressed air (in order to keep the animal away from the compressor unit), and finally of the ambient temperature were studied, this equipment being essentially used during the winter season. This equipment could accommodate the breathing needs of cattle weighing up to 225 kg if a pressure of 600 kPa was developed upstream to the nebulizers. The rate of atomization was significantly reduced when working at ambient air temperatures (272.25 K < T < 274.65 K) close to those encountered in winter. This was especially true when pressure upstream to the nebulizers did not exceed 500 kPa. The immersion of the feed pipe for compressed air in hot water led to an increase in the rate of atomization without raising evaporative water losses, and reduced the drop in temperature in the nebulizer solution. Finally, the rate of atomization significantly increased when the face mask including the nebulizers was maintained so that the nebulizers were in a vertical position or at an angle not less than 60 degrees with respect to the ground. [less ▲]

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See detailUse Of Bacteria Protections In Pelleting For Preinoculation Of Bean-Seeds (Phaseolus-Vulgaris L)
Jansen, Jp.; Schiffers, Bruno ULg; Mathot, P. et al

in Seed Science and Technology (1994), 22(2), 329-336

Preinoculation of bean seeds (Phaseolus vulgaris L.) with Rhibozium phaseoli material has been carried out by incorporating the inoculum in seed pelleting. An inoculum was incorporated into a mixture of ... [more ▼]

Preinoculation of bean seeds (Phaseolus vulgaris L.) with Rhibozium phaseoli material has been carried out by incorporating the inoculum in seed pelleting. An inoculum was incorporated into a mixture of vermiculite and compost or wheat bran, and applied to seeds to produce a solid pellet. The pelleted seed contained a sufficient number of bacteria per seed for effective nodulation after 56 days storage of preinoculated pelleted seeds at 25°C. Those results are not achieved using a liquid inoculum of Rhibozium. [less ▲]

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See detailGestion d'un épisode de peste porcine classique en Belgique
Vanthemsche, P.; Saegerman, Claude ULg

in Epidémiologie et Santé Animale (1994), 26

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See detailEvolutionary affiliation of the marine nitrogen-fixing cyanobacterium Trichodesmium sp. strain NlBB 1067, derived by 16s ribosomal RNA sequence analysis
Wilmotte, Annick ULg; Neefs, Jean-Marc; De Wachter, Rupert

in Microbiology (1994), 140

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial ... [more ▼]

The 165 rRNA sequence of Trichodesmium sp. strain NlBB 1067 was determined and used for the construction of a distance tree and bootstrap analysis. The tree shows that, among the available cyanobacterial 165 rRNA sequences, Trichodesmium NlBB 1067 has Oscillatoria PCC 7515 as its closest relative, presenting 94.9% of sequence similarity with the latter strain. This is in contrast to a difference of 9 mol O/O G + C in mean genomic DNA base composition between the two organisms. Nevertheless, the genotypic heterogeneity presented by a number of strains assigned to the genus Oscillatoria hinders a taxonomic decision on the separate existence of the genera Trichodesmium and Oscillatoria. The sequence of the internal transcribed spacer (ITS) between the 165 and 23s rRNA genes was also determined, as a possible marker to study inter- and intraspecif ic variability. The ITS contains the genes coding for tRNA1Ie and tRNAAia and its total length is 547 nucleotides. In six out of eight sequenced clones, there is a duplication of 29 nucleotides, surrounding the 5' end of the tRNA1Ie. [less ▲]

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