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See detail"Reprise" et "Charbons ardents" - la mémoire et la lutte
Servais, Christine ULiege

in Cinémaction (2003), 110

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See detailL'application dans le temps de la peine de travail
Jacobs, Ann ULiege

in Revue de Droit Pénal et de Criminologie (2003)

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See detailPrimary intraventricular brain abscess.
Lambo, A.; NCHIMI LONGANG, Alain ULiege; Khamis, J. et al

in Neuroradiology (2003), 45(12), 908-10

We report a primary intraventricular brain abscess in a 13-year-old boy. We discuss possible explanations for this rare occurrence.

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See detailThe core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo
Markine-Goriaynoff, N.; Georgin, J. P.; Goltz, M. et al

in Journal of Virology (2003), 77(3), 1784-1792

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To ... [more ▼]

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the Bo17 gene, we analyzed its distribution among BoHV-4 strains and determined the sequences of Bo17 from nine representative strains and of the C2GnT-M gene from six species of ruminants expected to encompass the group within which the gene acquisition occurred. Of 34 strains of BoHV-4, isolated from four different continents, all were found to contain the Bo17 gene. Phylogenetic analyses indicated that Bo17 was acquired from a recent ancestor of the African buffalo, implying that cattle subsequently acquired BoHV-4 by cross-species transmission. The rate of synonymous nucleotide substitution in Bo17 was estimated at 5 x 10(-8) to 6 x 10(-8) substitutions/site/year, consistent with previous estimates made under the assumption that herpesviruses have cospeciated with their hosts. The Bo17 gene acquisition was dated to around 1.5 million years ago. Bo17 sequences from BoHV-4 strains from African buffalo and from cattle formed two separate clades, estimated to have split about 700,000 years ago. Analysis of the ratio of nonsynonymous to synonymous nucleotide substitutions revealed a burst of amino acid replacements subsequent to the transfer of the cellular gene to the viral genome, followed by a return to a strong constraint on nonsynonymous changes during the divergence of contemporary BoHV-4 strains. The Bo17 gene represents the most recent of the known herpesvirus gene acquisitions and provides the best opportunity for learning more about this important process of viral evolution. [less ▲]

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See detailEinstein oscillators in thallium filled antimony skutterudites
Hermann, Raphaël ULiege; Jin, R. J.; Schweika, W. et al

in Physical Review Letters (2003), 90(13),

Inelastic neutron scattering measurements on several Tl filled skutterudites (Tl0.5Co3.5Fe0.5Sb12, Tl0.8Co3FeSb12, and Tl0.8Co4Sb11Sn) all show a sharp peak in the vibrational density of states at 57 ... [more ▼]

Inelastic neutron scattering measurements on several Tl filled skutterudites (Tl0.5Co3.5Fe0.5Sb12, Tl0.8Co3FeSb12, and Tl0.8Co4Sb11Sn) all show a sharp peak in the vibrational density of states at 57 +/- 2 K, which is absent in the unfilled skutterudite CoSb3. Heat capacity measurements on Tl0.8Co4Sb11Sn as compared to CoSb3 are consistent with the presence of a localized vibrational mode associated with the "rattling" thallium atoms in this filled skutterudite compound. Both results are well described by a localized Einstein mode model with an Einstein temperature Theta(E) of 53 +/- 1 K. These data provide perhaps the clearest example of local mode behavior in a concentrated metallic system. [less ▲]

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See detailLa problématique de la résistance des pneumocoques aux antibiotiques
Marchal, Valérie; Melin, Pierrette ULiege; Hayette, Marie-Pierre ULiege et al

in Revue Médicale de Liège (2003), 58(11), 675-680

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia and it is also a common cause of sinusitis, otitis media, bacteremia and meningitis. The increasing resistance to ... [more ▼]

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia and it is also a common cause of sinusitis, otitis media, bacteremia and meningitis. The increasing resistance to antimicrobial agents, now endemic in many countries, reflects an uncontrolled use of antibiotics. A good antibiotics policy and vaccination are at the moment the only way to control efficaciously the increasing antibiotic resistance of Streptococcus pneumoniae [less ▲]

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See detailNumerus clausus en fin de troisieme candidature en medecine: mort annoncee d'une heresie?
Rabenda, Véronique ULiege; Boniver, Jacques ULiege; Reginster, Jean-Yves ULiege

in Revue Médicale de Liège (2003), 58(7-8, Jul-Aug), 508-14

Owing to the establishment of a procedure aiming at a reduction of the medical supply (numerus clausus), the French Community of Belgium had decided to introduce, at the end of the third year of medical ... [more ▼]

Owing to the establishment of a procedure aiming at a reduction of the medical supply (numerus clausus), the French Community of Belgium had decided to introduce, at the end of the third year of medical studies (third candidature), a procedure of selective attribution of the certificate allowing for a unlimited medical practice. We assessed the predictive value of the results obtained during and at the end of the first candidature (first year of medicine) for the attribution of this certificate. We studied the results of the 225 students enrolled in the first candidature in medicine at the University of Liege during the academic year 1997-1998, and we correlated them to the subsequent attribution (1999-2000- and 2000-2001) of the certificate. The success of the first candidature in the first or second session is an important predicting factor towards the reception of the certificate. A non-authorization to continue the studies in medicine in case of failure in the first session or a non-authorization to repeat the first candidature in case of failure in the second session would have, respectively, a negative predictive value (NPV) of 91.9% and 97.4% and would allow to restream 111 students at the end of the first session or 39 students at the end of the first candidature. The results of the preliminary assessments mode during the month of January are also highly predictive of the chances to get the certificate. Among the 160 students who have not successfully passed a minimum of 3 exams, only 14 students obtained the certificate. The restreaming of those students would correspond to a NPV of 91.2%. Students who were not successful in a minimum of 2 exams would have less than 5% chance to obtain the certificate. In this case, 109 students would be restreamed (NPV = 95.4%). In conclusion, the selection of the students who will obtain, at the end of the third year of medicine, the certificate allowing them for an unlimited medical practice is obtained, in a large proportion, during the first candidature and especially after the session of January. In view of those results and considering the decree abolishing the selection at the end of the third year of medical studies, one could argue about the appropriateness of the current procedure, chosen by the French Community of Belgium, compared to other solutions prioritising an earlier selection of the future doctors. [less ▲]

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See detailWhat's alternative about alternative food networks?
Whatmore, Sarah; Stassart, Pierre M ULiege; Rentjes, Henk

in Environment & Planning A (2003), 35

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See detailRecent developments in 5-lipoxygenase inhibitors
Julémont, F.; Dogné, J.-M.; Laeckmann, D. et al

in Expert Opinion on Therapeutic Patents (2003), 13

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See detailA new method for reconstruction of the vertical electron density distribution in the upper ionosphere and plasmasphere
Stankov, Stanimir; Jakowski, Norbert; Muhtarov, Plamen et al

in Journal of Geophysical Research. Space Physics (2003), 108(A51164), 1164

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See detailLa motivation du refus de prononcer une peine de travail
Jacobs, Ann ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2003)

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See detailThe role of reactive oxygen species in homeostasis and degradation of cartilage.
Henrotin, Yves ULiege; Bruckner, P.; Pujol, J. P.

in Osteoarthritis and Cartilage (2003), 11(10), 747-55

OBJECTIVES: The metabolism of cells in articular joint tissues in normal and pathological conditions is subject to a complex environmental control. In addition to soluble mediators such as cytokines and ... [more ▼]

OBJECTIVES: The metabolism of cells in articular joint tissues in normal and pathological conditions is subject to a complex environmental control. In addition to soluble mediators such as cytokines and growth factors, as well as mechanical stimuli, reactive oxygen species (ROS) emerge as major factors in this regulation. ROS production has been found to increase in joint diseases, such as osteoarthritis and rheumatoid arthritis, but their role in joint diseases initiation and progression remains questionable. METHOD: This review is focused on the role of ROS, mainly nitric oxide, peroxynitrite and superoxide anion radicals, in the signaling mechanisms implied in the main cellular functions, including synthesis and degradation of matrix components. The direct effects of ROS on cartilage matrix components as well as their inflammatory and immunomodulatory effects are also considered. RESULTS: Some intracellular signaling pathways are redox sensitive and ROS are involved in the regulation of the production of some biochemical factors involved in cartilage degradation and joint inflammation. Further, ROS may cause damage to all matrix components, either by a direct attack or indirectly by reducing matrix components synthesis, by inducing apoptosis or by activating latent metalloproteinases. Finally, we have highlighted the uncoupling effect of ROS on tissue remodeling and synovium inflammation, suggesting that antioxidant therapy could be helpful to treat structural changes but not to relieve symptoms. CONCLUSIONS: This review of the literature supports the concept that ROS are not only deleterious agents involved in cartilage degradation, but that they also act as integral factors of intracellular signaling mechanisms. Further investigation is required to support the concept of antioxidant therapy in the management of joint diseases. [less ▲]

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See detailThe inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding.
Damblon, Christian ULiege; Jensen, Mikael; Ababou, Abdessamad et al

in Journal of Biological Chemistry (2003), 278(31), 29240-51

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and ... [more ▼]

Thiomandelic acid is a simple, broad spectrum, and reasonably potent inhibitor of metallo-beta-lactamases, enzymes that mediate resistance to beta-lactam antibiotics. We report studies by NMR and perturbed angular correlation (PAC) spectroscopy of the mode of binding of the R and S enantiomers of thiomandelic acid, focusing on their interaction with the two metal ions in cadmium-substituted Bacillus cereus metallo-beta-lactamase. The 113Cd resonances are specifically assigned to the metals in the two individual sites on the protein by using 113Cd-edited 1H NMR spectra. Each enantiomer of thiomandelate produces large downfield shifts of both 113Cd resonances and changes in the PAC spectra, which indicate that they bind such that the thiol of the inhibitor bridges between the two metals. For R-thiomandelate, this is unambiguously confirmed by the observation of scalar coupling between Halpha of the inhibitor and both cadmium ions. The NMR and PAC spectra reveal that the two chiral forms of the inhibitor differ in the details of their coordination geometry. The complex with R-thiomandelate, but not that with the S-enantiomer, shows evidence in the PAC spectra of a dynamic process in the nanosecond time regime, the possible nature of which is discussed. The thiomandelate complex of the mononuclear enzyme can be detected only at low metal to enzyme stoichiometry; the relative populations of mononuclear and binuclear enzyme as a function of cadmium concentration provide clear evidence for positive cooperativity in metal ion binding in the presence of the inhibitor, in contrast to the negative cooperativity observed in the free enzyme. [less ▲]

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See detailCompte rendu d’Adrienne et Luc Fontainas, et Émile Van Balberghe, Publications de la Librairie Deman. Bibliographie
Durand, Pascal ULiege

in Textyles : Revue des Lettres Belges de Langue Française (2003)

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See detailDesign and methodology of the phase 3 trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis
Meunier, P. J.; Reginster, Jean-Yves ULiege

in Osteoporosis International (2003), 14(Suppl. 3), 66-76

The phase 3 program for strontium ranelate, a new oral agent in the treatment of women with postmenopausal osteoporosis, was aimed to assess the efficacy and safety of the daily oral dose of 2 g. This ... [more ▼]

The phase 3 program for strontium ranelate, a new oral agent in the treatment of women with postmenopausal osteoporosis, was aimed to assess the efficacy and safety of the daily oral dose of 2 g. This program was conducted in 12 countries, involved 75 centers, and was structured in 3 studies: FIRST (Fracture International Run-in for Strontium ranelate Trial), SOTI (Spinal Osteoporosis Therapeutic Intervention study) and TROPOS (TReatment Of Peripheral OSteoporosis). FIRST, a run-in open study, was designed to start the normalization of the calcium and vitamin D status of the patients, check all entry criteria, and ensure inclusion of a sufficient number of well-motivated patients in either one of the two therapeutic intervention protocols, SOTI or TROPOS: FIRST included 9,196 patients. SOTI and TROPOS were prospective, randomized, double-blind clinical trials comparing, in two parallel groups, the daily oral dose of 2 g of strontium ranelate with placebo, the patients of both groups receiving calcium and vitamin D according to their own deficiencies. The main objective of SOTI and TROPOS was to demonstrate a reduction in the incidence of postmenopausal women experiencing a new osteoporotic fracture (vertebral fracture in SOTI and nonvertebral fracture in TROPOS) over a 3-year treatment period, the total duration of the studies being 5 years. SOTI included 1,649 women with at least one osteoporotic vertebral fracture at inclusion and a lumbar BMD less than or equal to 0.840 g/cm(2). TROPOS included 5,091 women with a femoral neck BMD less than or equal to 0.600 g/cm(2). The phase 3 program for the clinical development of strontium ranelate in women with postmenopausal osteoporosis is a long-term program with the main statistical analysis after 3 years of treatment. Its aim is to demonstrate the effect of strontium ranelate on the axial and appendicular skeleton as well as its tolerability in osteoporotic patients with replete calcium and vitamin D stores. [less ▲]

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See detailProspective studyof CD4 and CD8 T-lynphocyte apoptosis as a marker for radiation induced late effects in 399 individual patients
Ozsahin; Crompton; Shi et al

in International Journal of Radiation, Oncology, Biology, Physics (2003), 55(2), 551-552

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See detailReactive oxygen species downregulate the expression of pro-inflammatory genes by human chondrocytes.
Mathy, Marianne ULiege; Martin, G.; Devel, P. et al

in Inflammation Research (2003), 52(3), 111-8

OBJECTIVES: To determine the regulatory effects of reactive oxygen species (ROS) on the expression by human osteoarthritic chondrocytes of interleukin (IL)-1beta, -6 and -8, inducible nitric oxide ... [more ▼]

OBJECTIVES: To determine the regulatory effects of reactive oxygen species (ROS) on the expression by human osteoarthritic chondrocytes of interleukin (IL)-1beta, -6 and -8, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) gene in response to interleukin (IL)-1beta or lipopolysaccharide (LPS). METHODS: Human chondrocytes in monolayer culture were incubated for 3 h with ROS generating molecules such as S-nitroso-N-acetyl-D,L-penicillamine (SNAP, 100 microM), 3-morpholinosydnonimine (SIN-1, 100 microM), with chemically synthesised peroxynitrite (ONOO-, 10 microM) or hydrogen peroxide (H2O2, 100 microM). After treatment by ROS, chondrocytes were washed and then cultured for the next 24 h with or without lipopolysaccharide LPS (10 microg/ml) or IL-1beta (1.10(-11) M). IL-1beta, IL-6, IL-8, iNOS and COX-2 gene expression was analysed by real time and quantitative RT PCR. IL-6, IL-8 and prostaglandin (PG) E2 productions were assayed by specific immunoassays. Nitrite was measured in the culture supernatants by the Griess procedure. RESULTS: LPS and IL-1beta stimulated IL-1beta, IL-6, IL-8, iNOS and COX-2 gene expression. SNAP significantly downregulated LPS induced overall gene expressions, whereas SIN-1 had no effect. ONOO- inhibited iNOS and COX-2 gene expression but not that of the cytokine genes. When chondrocytes were incubated with IL-1beta, SIN-1 and ONOO dramatically decreased all gene expressions while SNAP was inefficient. H2O2 treatment inhibited both LPS and IL-1beta induced gene expressions. CONCLUSIONS: These data provide an evidence that ROS may have anti-inflammatory properties by depressing inflammatory gene expression. Further, we demonstrate that ROS effects are dependent on the nature of radical species and the signalling pathway that is activated. These findings should be taken into consideration for the management of antioxidant therapy in treatment of inflammatory joint diseases. [less ▲]

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See detailCharge exchange in tandem mass spectrometry: dissociative single electron capture by doubly-charged toluene cations
Fati, D.; Leyh, Bernard ULiege

in European Journal of Mass Spectrometry (Chichester, England) (2003), 9(4), 223-235

Single electron capture by doubly-charged toluene cations upon collision with various target gases has been investigated by sector tandem mass spectrometry. Both non-dissociative and dissociative charge ... [more ▼]

Single electron capture by doubly-charged toluene cations upon collision with various target gases has been investigated by sector tandem mass spectrometry. Both non-dissociative and dissociative charge transfer reactions leading to C(7)H(7)(+) + H and to C(5)H(5)(+) + [C(2),H(3)] are detected. Seven atomic or molecular target gases have been used with ionisation energies ranging from 8.8 eV to 14 eV. The branching ratios between the different non-dissociative and dissociative exit channels have been determined as well as the translational energy release on the dissociation products. The experimental data are compared to the predictions of a two-state semi-classical theoretical model that takes into account the non-adiabatic transition responsible for the charge transfer reaction. A wide reaction window shows up but the internal energies of the C(7)H(8)(+) cations produced by single electron capture are observed to be larger than expected. We assign this effect partly to the influence of the large density of vibrational states and to the multichannel nature of the process. Excited states of the dication are also most probably involved in the charge exchange reaction. [less ▲]

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See detailPour lire Pédigrée
Dumortier, Jean-Louis ULiege

in Dossiers L (Littérature française de Belgique (2003), 64(4),

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See detailEstrogens reduce the expression of YKL-40 in the retina: Implications for eye and joint diseases
Rakic, Jean-Marie ULiege; Lambert, Vincent ULiege; Deprez, Manuel ULiege et al

in Investigative Ophthalmology & Visual Science (2003), 44(4), 1740-1746

PURPOSE. To identify modifications in the gene expression profile of the ocular posterior segment in ovariectomized (OVX) mice with and without substitutive estradiol therapy and to select differentially ... [more ▼]

PURPOSE. To identify modifications in the gene expression profile of the ocular posterior segment in ovariectomized (OVX) mice with and without substitutive estradiol therapy and to select differentially expressed genes that could be relevant to the natural history of human age-related macular degeneration (AMD). METHODS. Chorioretinal tissues from two groups of 25 treated and untreated OVX mice were analyzed by using cDNA array technology. The expression level of selected genes was confirmed in triplicate by RT-PCR and related to the estrogenic status of the animals. Expression of the YKL-40 gene was further investigated in intact or diseased human retinas and in a murine model of experimental choroidal neovascularization (CNV), using laser pressure catapulting. RESULTS. Of the approximately, 10,000 genes screened, only YKL-40 expression was significantly downregulated by 17-beta-estradiol. YKL-40 was expressed in intact human neural retina and in the RPE. The expression of YKL-40 was upregulated in experimental CNV and in neovascular membranes extracted from patients affected by the exudative form of AMD. CONCLUSIONS. These observations indicate that YKL-40 expression in the retina is modulated by serum levels of estradiol. This protein could be relevant to the development of AMD and is also a new mediator to take into account when evaluating the broad consequences of hormonal replacement therapy. [less ▲]

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See detailEffects Of The Nature Of Nitrogen Supplementation On Voluntary Intake, Rumen Parameters And Ruminal Degradation Of Dry Matter In Sheep Fed Oat Silage-Based Diets
Mahouachi, Mokhtar; Haddad, L.; Kayouli, Chedly et al

in Small Ruminant Research (2003), 48(3), 181-187

The effects of nature of nitrogen supplementation on silageDMintake (SDMI), totalDMintake (TDMI), rumen parameters and ruminal degradation of DM of silage and wheat straw were studied using four adult ... [more ▼]

The effects of nature of nitrogen supplementation on silageDMintake (SDMI), totalDMintake (TDMI), rumen parameters and ruminal degradation of DM of silage and wheat straw were studied using four adult Noire de Thibar rams. Silage was made from predominantly oats harvested at milk stage and ensiled without preservative. The silage was offered ad libitum as the sole diet (OS) or supplemented with 450 g DM of iso-nitrogen (25.6 g/kg DM) and iso-energy (0.8 Unité Fourragère Lait: UFL/kg DM) concentrate containing soybean meal (SBM), urea (UR) or poultry litter (PL) as nitrogen supplements. SDMI (g/kgW0.75 × day) and TDMI (g/kgW0.75 × day) were affected (P < 0.001) by the type of supplement and averaged 63.9, 60.1, 54.9, 51.1 and 63.9, 81.4, 74.8, 72.2 for OS, SBM, PL and UR diets, respectively. In comparison with other diets, SBM diet systematically decreased (P < 0.05) the pH of the rumen after the morning feeding and reduced the rumen concentration of total VFA at 1 h after feeding. SBM diet decreased DM disappearance of the oat silage incubated in nylon bags for 72 h (P < 0.05), but not of wheat straw. The three supplements increased the ammonia-N concentrations in the rumen for several hours after feeding in comparison with the OS diet. However, only the SBM diet kept this difference just before the next meal. It is concluded that despite its low nutritive value (0.62 UFL and 108 g crude protein/kg DM), the oat silage is well consumed by the local ruminants accustomed to use poor forages for a long time. In Tunisia, poultry litter may be used as a nitrogen source to supplement the oat silage for sheep. [less ▲]

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See detailL’insuffisance mitrale chez le cheval : revue de littérature.
Maurin, Emmanuel; Amory, Hélène ULiege; Sandersen, Charlotte ULiege

in Pratique Vétérinaire Equine (2003), 35

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See detailThe State, the Market and Cultural Diversity
Martiniello, Marco ULiege

in Immigrants & Minorities (2003), 22(2-3), 127-140

This essay compares the logic of states & the logic of markets in the management of cultural diversity. On the one hand, the economic logic of markets leads to an encouragement of a 'soft' cultural ... [more ▼]

This essay compares the logic of states & the logic of markets in the management of cultural diversity. On the one hand, the economic logic of markets leads to an encouragement of a 'soft' cultural diversity associated with the marketing of exoticism in music, the arts, & cuisine, for example. On the other hand, the liberal states are trapped between their willingness to recognize some form of diversity & their fear of seeing social cohesion harmed by this recognition. In other words, the essay applies Hollified's hypothesis about the liberal paradox in immigration policy to the sphere of cultural diversity in post-immigration situations. Adapted from the source document. [less ▲]

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See detailDiagnostic et suivi de la gravidité chez le zébu par échographie
Pitala, W.; Boly, H.; Zongo, M. et al

in Revue d'Elévage et de Médecine Vétérinaire des Pays Tropicaux (2003), 56(3-4), 171-176

Des diagnostics de gravidité ont été réalisés chez 64 femelles zébus de races Peuhl et Goudali (Bos indicus) aux 28è et 40è jours postinsémination à l'aide d'un échographe muni d'une sonde linéaire de 6 ... [more ▼]

Des diagnostics de gravidité ont été réalisés chez 64 femelles zébus de races Peuhl et Goudali (Bos indicus) aux 28è et 40è jours postinsémination à l'aide d'un échographe muni d'une sonde linéaire de 6 MHz. Au 28è jour, l'exactitude globale a été de 92,2 p. 100, avec une exactitude de 92,6 p. 100 et 91,9 p. 100 respectivement pour les diagnostics positif et négatif. Au 40è jour, l'exactitude globale a été de 98,4 p. 100, avec une exactitude de 100 p. 100 et 97,3 p. 100 respectivement pour les diagnostics positif et négatif. Les fiabilités ont varié de 89,2 p. 100 (fiabilité du diagnostic de gravidité positif au 28è jour) à 100 p. 100 (fiabilité du diagnostic de gravidité négatif au 40è jour). Par ailleurs, la croissance foetale a été suivie chez 16 femelles gravides du 45è au 120è jour postinsémination. Les principales mensurations foetales réalisées ont été les diamètres du crâne et du tronc. Au 45è jour de la gravidité, les diamètres du crâne et du tronc ont été respectivement de 1,8 ± 0,1 cm et 1,4 ± 0,3 cm. Au 120è jour, ces valeurs ont été de 6,5 ± 0,6 cm et 5,8 ± 0,5 cm. A partir du 120è jour, l'utérus a pris une position très profonde, ne permettant plus la visualisation du foetus en croissance. [less ▲]

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See detailL’enseignement universitaire demain. Le cas de la Belgique francophone
Merenne-Schoumaker, Bernadette ULiege

in Géographes Associés (2003), (27), 63-65

Courte présentation de la situation de la géographie dans le monde universitaire francophone de Belgique au moment de la Réforme de Bologne

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See detailIdentités et valeurs politiques : quelle homogénéité pour l'Eurégio ?
Jacquemain, Marc ULiege

in Fédéralisme - Régionalisme (2003)

Euregio Mosa-Rhine is a euregional structure that agregates Province of Liege and German-speaking belgian community (Belgium) Province of Limburg (Belgium), Province of South-Limburg (Netherlands) and ... [more ▼]

Euregio Mosa-Rhine is a euregional structure that agregates Province of Liege and German-speaking belgian community (Belgium) Province of Limburg (Belgium), Province of South-Limburg (Netherlands) and Regio Aachen (Germany). It is supposed to be an area with many commercial and cultural inter-relations. Throuth a survey led in 2002, the paper tries to assess cultural similitaries and differences between the five components at the level of social identity and political values. It shows a contrasted landscape where the two dutch-speaking parts being more individualist, the german part being more comunitarian and, at the heart, the province of Liege more materialist and egalitarian. [less ▲]

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See detailLes facteurs de virulence des alphaherpèsvirus
Muylkens, Benoît ULiege; Meurens, François; Schynts, Frédéric et al

in Virologie (2003), 7

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See detailChanges in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine.
Legssyer, Rachida; Josse, Claire ULiege; Piette, Jacques ULiege et al

in Journal of Inorganic Biochemistry (2003), 94(1-2), 36-42

Both desferrioxamine (DFO) and chloroquine can significantly reduce hepatic iron in experimental animals with iron overload by chelating iron from the low-molecular-weight pool or decreasing iron uptake ... [more ▼]

Both desferrioxamine (DFO) and chloroquine can significantly reduce hepatic iron in experimental animals with iron overload by chelating iron from the low-molecular-weight pool or decreasing iron uptake by the transferrin-transferrin receptor cycle, respectively. However, no previous studies have investigated whether combination therapy of these two drugs would further decrease the tissue iron overload as well as iron-induced toxicity. Chloroquine administration, 15 mg/kg, 5x/week, to rats during the iron loading regime, 10 mg/kg, 3x/week for 4 weeks, significantly decreased both hepatic (54%) and macrophage iron content (24%). However when administered in combination with desferrioxamine, 10 mg/kg, 3x/week for 2 weeks at the cessation of iron loading, no further reduction of hepatic iron content was noted while the iron content of the macrophages significantly increased, possibly indicating the flux of ferrioxamine through these cells. Further studies are warranted to investigate the speciation of iron within these macrophages. Macrophages isolated from chloroquine-treated iron loaded rats showed a reduction in latent NFkappaB activation and a significant increase in lipopolysaccharide-stimulated nitrite release by comparison to these parameters in iron loaded macrophages. Co-administration of chloroquine and desferrioxamine normalised the latent activity of NFkappaB to that of control macrophages as well as increasing LPS-stimulated NO release towards control values. However, DFO alone did not have any significant effect upon either of these parameters. Such results may have important relevance for the reduced immune function of iron loaded macrophages isolated from thalassaemia patients receiving chelation therapy and their propensity to increased infection. [less ▲]

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See detailLe Mole National Park (Ghana). Une expérience réussie d’écotourisme pédestre
Vermeulen, Cédric ULiege; Portier, B.

in Parcs & Réserves (2003), 58(1), 3-6

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See detailDiagnostic différentiel en cas de présomption de myopathie atypique des équidés : illustration au travers de cas référés à la Faculté de Médecine Vétérinaire de l’Université de Liège au cours du printemps 2003
Votion, Dominique ULiege; Delguste, Catherine ULiege; Baise, Etienne ULiege et al

in Annales de Médecine Vétérinaire (2003), 147

Atypical myopathy is a frequently fatal disease inducing extensive and severe muscular damage, occurring during autumn and spring in grazing horses. The main features of the syndrome are the sudden onset ... [more ▼]

Atypical myopathy is a frequently fatal disease inducing extensive and severe muscular damage, occurring during autumn and spring in grazing horses. The main features of the syndrome are the sudden onset of non pathognomonic symptoms such as weakness, stiffness, sudation, recumbency and when observed, emission of dark urine. Confirmation of the diagnosis is of paramount importance since the disease can be recurrent on limited geographic area. This paper discusses the methodology applied on 7 clinical cases referred with a symptomatology suggestive of atypical myopathy to the Faculty of Veterinary Medicine at Liege University during the spring 2003. Two of those cases were confirmed for atypical myopathy. A presumption of atypical myopathy may be drawn on history and clinical signs. On living animals, the serum concentration of the creatinine phosphokinase enzyme is the most useful biochemical tests as an aid to diagnosis because it confirms the presence of muscle damage. Nevertheless, the definitive diagnosis requires the histological examination of specific muscular samples obtained post-mortem. [less ▲]

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See detailCultures maraîchères et insectes utiles
Francis, Frédéric ULiege; Colignon, Pierre; Haubruge, Eric ULiege

in Le Canard déchaîné du Kauwberg (2003), 46

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See detailEquine trypsin: purification and development of a radio-immunoassay
Grulke, Sigrid ULiege; Deby-Dupont, G.; Gangl, M. et al

in Veterinary Research (2003), 34(3, May-Jun), 317-330

Shock is accompanied by generalised splanchnic hypoperfusion, and splanchnic organs like the pancreas can be damaged, as shown in animal experimental models and in humans, by the presence of high plasma ... [more ▼]

Shock is accompanied by generalised splanchnic hypoperfusion, and splanchnic organs like the pancreas can be damaged, as shown in animal experimental models and in humans, by the presence of high plasma concentrations of trypsin and other pancreatic enzymes. In order to design a radioimmunoassay technique (RIA) for the measurement of equine trypsin-like immunoreactivity (TLI) in biological fluids, trypsin was purified (with purity greater than or equal to 96 %) from the equine pancreas by extraction in an acid medium, ammonium sulfate precipitations, gel filtration chromatography and, after activation of trypsinogen into trypsin, affinity chromatography. Gel polyacrylamide electrophoresis showed a monomeric enzyme with a molecular weight of 27 kDa. The purified equine trypsin served for the immunisation of rabbits in order to obtain a specific antiserum, and the labelled antigen was prepared by iodination of equine trypsin with I-125. The RIA was based on the binding of the antigen to the antibody followed by the separation of the antigen-antibody complex by immunoprecipitation in the presence of sheep anti-rabbit gammaglobulins and the assay of the radioactivity in the precipitate. The RIA showed good sensitivity, specificity, precision, accuracy and reproducibility. The reference mean value of TLI in the plasma of healthy horses (n = 20) was 30.01 +/- 6.84 ng/mL (upper confidence limit 50.52 ng/mL; p < 0.01). Three horses with non strangulating intestinal obstruction without shock showed TLI values within normal limits whereas 5 of 7 horses with strangulation obstruction showed TLI levels above the upper confidence limit. Further studies using the RIA and the enzymatic assay should be performed in order to confirm the role of the pancreas in equine intestinal obstruction. [less ▲]

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See detailEtude comparative des caractéristiques physiques et mécaniques du bois des mélèzes d'Europe (Larix decidua Mill.), du Japon (Larix kaempferi (Lambert) Carr.) et de leur hybride (Larix x eurolepis Henry).
Charron, Stéphane; Jourez, Benoît ULiege; Marchal, Michèle et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2003), 7(1), 5-16

This present research aims to compare physical and mechanical characteristics between two larch species and their hybrid (Larix decidua Mill., Larix kaempferi (Lambert) Carr. et Larix x eurolepis Henry ... [more ▼]

This present research aims to compare physical and mechanical characteristics between two larch species and their hybrid (Larix decidua Mill., Larix kaempferi (Lambert) Carr. et Larix x eurolepis Henry). From each species, normalised samples have been sawn from five trees, and <br />submitted to normalised tests according to the norms NBN 225, NF B 51-016 and DIN 52189. The Japanese (Larix kaempferi (Lambert) Carr.) and hybrid (Larix x eurolepis Henry) larches present similar physical and mechanical properties, always lower than those observed for the European one. This is partly explained by a higher mean wood density for this species. <br />Whatever the species, juvenile wood presents lower physical and mechanical properties than mature wood. The larch wood produced in the Walloon Region presents a large technological potential that it is interesting to promote, without forgetting to adapt the classification procedures. Consequently, larch appears to be a versatile species, which can be used for numerous purposes, inside as well as outside. [less ▲]

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See detailLa Vie de saint Lambert du chanoine Nicolas (ca 1145) et l’élection du prince-évêque Henri de Leez (1145-1162)
Adam, Renaud ULiege

in Bulletin de l'Institut Archéologique Liégeois (2003), 111

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See detailThe neuroendocrinology of reproductive behavior in Japanese quail
Balthazart, Jacques ULiege; Baillien, Michelle; Charlier, Thierry ULiege et al

in Domestic Animal Endocrinology (2003), 25

Sex steroid hormones such as testosterone have widespread effects on brain physiology and function but one of their best characterized effects arguably involves the activation of male sexual behavior ... [more ▼]

Sex steroid hormones such as testosterone have widespread effects on brain physiology and function but one of their best characterized effects arguably involves the activation of male sexual behavior. During the past 20 years we have investigated the testosterone control of male sexual behavior in an avian species, the Japanese quail (Coturnix japonica).We briefly reviewhere the main features and advantages of this species relating to the investigation of fundamental questions in the field of behavioral neuroendocrinology, a field that studies inter-relationship among hormones, brain and behavior. Special attention is given to the intracellular metabolism of testosterone, in particular its aromatization into an estrogen, which plays a critical limiting role in the mediation of the behavioral effects of testosterone. Brain aromatase activity is controlled by steroids which increase the transcription of the enzyme, but afferent inputs that affect the intraneuronal concentrations of calcium also appear to have a pronounced effect on the enzyme activity through rapid changes in its phosphorylation status. The physiological significance of these slowgenomic and rapid, presumably non-genomic, changes in brain aromatase activity are also briefly discussed. [less ▲]

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See detailQuantitative dynamics of PCB transfer from mother to pup during lactation in UK grey seals Halichoerus grypus
Debier, Cathy; Pomeroy, Paddy P.; Dupont, Cédric et al

in Marine Ecology-Progress Series (2003), 247

PCB contamination was measured in the milk and serum of grey seal Halichoerus grypus mothers and in the serum of their pups sampled from 2 to 5 times between parturition and weaning on the Isle of May ... [more ▼]

PCB contamination was measured in the milk and serum of grey seal Halichoerus grypus mothers and in the serum of their pups sampled from 2 to 5 times between parturition and weaning on the Isle of May, Scotland, in 1998 and 2000. Blubber biopsies were also taken from the lactating females at early and late lactation in 2000. Concentrations of PCBs in milk stayed constant during the first part of lactation (0.31 +/- 0.17 mug g milk(-1)) and then increased at late lactation (0.67 +/- 0.42 mug g milk(-1)). Curiously, it did not follow the changes of milk lipid content, which increased at early lactation and then stayed constant until the end of the nursing period. As a result, even when expressed per unit of milk lipids, PCBs underwent a rise at the end of lactation. The changes in milk PCBs were accompanied by similar dynamics in maternal serum as well as in pup serum. Increased concentrations of PCBs at late lactation in serum and milk may be explained in part by the changes observed in maternal blubber. PCB levels increased significantly between early and late lactation in inner blubber, suggesting that PCBs are less easily mobilised from blubber than lipids. At late lactation, the retention capacity of the reduced blubber layer for PCBs might have reached its maximum. The mobilization of less polar lipids from blubber might also occur at this stage. In both cases, this could result in a higher mobilization of PCBs at this time. While inner blubber was significantly less concentrated than outer blubber at early lactation (1.26 +/- 0.72 mug g lipids(-1) in inner blubber vs 3.16 +/- 1.34 mug g lipids(-1) in outer blubber), these variations disappeared at late lactation (3.24 +/- 2.60 mug g lipids(-1) in inner blubber vs 3.59 +/- 1.46 mug g(-1) lipids in outer blubber). Newborn pups already had significantly higher serum levels of PCBs than their mothers, revealing an important placental transfer (11.9 +/- 7.0 ng ml serum(-1) in pups vs 6.7 +/- 3.5 ng ml serum(-1) in mothers). These differences were even greater in late lactation, due to the ingestion of milk (27.9 +/- 18.1 ng ml serum(-1) in pups vs 12.2 +/- 7.2 ng ml serum(-1) in mothers). As lactation progressed, PCB levels in pup serum increased exponentially as compared to the levels in the serum of their mothers. [less ▲]

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See detailStrontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies
Reginster, Jean-Yves ULiege; Meunier, P. J.

in Osteoporosis International (2003), 14(Suppl. 3), 56-65

The aim of the PREVOS study (PREVention Of early postmenopausal bone loss by Strontium ranelate) and the STRATOS study (STRontium Administration for Treatment of OSteoporosis) was to determine the minimum ... [more ▼]

The aim of the PREVOS study (PREVention Of early postmenopausal bone loss by Strontium ranelate) and the STRATOS study (STRontium Administration for Treatment of OSteoporosis) was to determine the minimum dose at which strontium ranelate (SR) is effective in, respectively, the prevention of bone loss in early postmenopausal nonosteoporotic women and the treatment of postmenopausal vertebral osteoporosis. Both studies were randomized, double-blind, placebo-controlled, dose-finding studies in parallel groups and lasted 2 years. In the PREVOS study, 160 early postmenopausal women were randomized to receive placebo, SR 125 mg/day, 500 mg/day or 1 g/day. In the STRATOS study, 353 osteoporotic postmenopausal women with at least one previous vertebral fracture and a lumbar T-score < -2.4 were randomized to receive placebo, SR 500 mg/day, 1 g/day or 2 g/day. In both studies, the primary efficacy parameter was lumbar bone mineral density (BMD) measured by dual-energy X-ray absorptiometry. Secondary efficacy criteria included incidence of new vertebral deformities (in the STRATOS study only) and biochemical markers of bone metabolism. In the PREVOS study, the increase in lumbar BMD from baseline in the 1 g/day group (+ 5.53%) was significantly different from the decrease in the placebo group (p < 0.001). In the STRATOS study, the annual increase in lumbar BMD in the 2 g/day group (+7.3% per year) was significantly higher than in the placebo group (p<0.001). There was a significant reduction in the number of patients experiencing new vertebral deformities in the second year of treatment in the 2 g/day group (relative risk: 0.56; 95% confidence interval: 0.35, 0.89). In both studies, there was a significant increase in the bone formation marker (bone alkaline phosphatase) in the higher-dose group. Urinary excretion of the marker of bone resorption (cross-linked N-telopeptide) was lower with SR than with placebo in the STRATOS study. SR was very well tolerated in both studies. The minimum dose at which SR is effective in preventing bone loss in early postmenopausal nonosteoporotic women and in the treatment of postmenopausal osteoporosis is 1 g/day and 2 g/day, respectively. [less ▲]

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See detailIncidence and survival rate of women with cervical cancer in the Greater Amsterdam area.
BULK, Saskia ULiege; Visser, O.; Rozendaal, L. et al

in British journal of cancer (2003), 89(5), 834-9

To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a ... [more ▼]

To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a cancer registry in the Greater Amsterdam area. The incidence rate of squamous cell carcinoma decreased significantly from 9.2/100,000 women in 1988 to 5.9/100,000 in 2000 (P<0.001). The incidence rate of adenocarcinomas remained stable. After adjustment for age, stage and lymph node involvement, the relative risk of death was 1.6 times higher for patients with adenocarcinomas than for patients with squamous cell carcinoma (95% CI 1.2-2.1). The decreased survival was related to histological type, as the effect remained significant after correction for confounding factors. Over time, the prognosis of women with squamous cell carcinoma improved significantly. No significant change was observed for women diagnosed with adenocarcinoma. These results suggest that the screening programme in The Netherlands as executed in the Greater Amsterdam area is associated with a decreased incidence and increased survival of patients with squamous cell carcinoma, but fails to detect (pre)malignant lesions of adenocarcinoma. Since more than 92% of adenocarcinomas and its precursors contain high-risk HPV, adding HPV testing to cytologic screening might improve the present screening programme in detecting adenocarcinoma and its precursor lesions. [less ▲]

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See detailMagnetic and mossbauer spectral study of ErFe11Ti and ErFe11TiH
Piquer, C.; Hermann, Raphaël ULiege; Grandjean, Fernande ULiege et al

in Journal of Applied Physics (2003), 93(6), 3414-3421

X-ray diffraction, isothermal magnetization at 5 and 300 K, ac magnetic susceptibility measurements between 5 and 200 K, and iron-57 Mossbauer spectral measurements between 4.2 and 295 K have been carried ... [more ▼]

X-ray diffraction, isothermal magnetization at 5 and 300 K, ac magnetic susceptibility measurements between 5 and 200 K, and iron-57 Mossbauer spectral measurements between 4.2 and 295 K have been carried out on ErFe11Ti and ErFe11TiH. Hydrogen uptake has been measured by gravimetric analysis and the insertion of hydrogen into ErFe11Ti increases its magnetization, magnetic hyperfine fields, and isomer shifts as a result of the associated lattice expansion. Peaks and steplike changes in both the real and imaginary components of the ac magnetic susceptibility are observed at similar to50 and 40 K for ErFe11Ti and ErFe11TiH, respectively, and are assigned to spin-reorientation transitions resulting from the temperature dependence of the sixth-order Stevens crystal-field term of erbium. The Mossbauer spectra have been analyzed with a model which considers both these spin reorientations and the distribution of titanium atoms in the near-neighbor environment of the three crystallographically distinct iron sites. The assignment and the temperature dependencies of the hyperfine fields and isomer shifts are in complete agreement with the Wigner-Seitz cell analysis of the three iron sites in ErFe11Ti and ErFe11TiH. The changes in the hyperfine field and isomer shift with the number of titanium near neighbors of the three iron sites are in agreement with the values observed for related titanium-iron intermetallic compounds. (C) 2003 American Institute of Physics. [less ▲]

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See detailBook Review: Theories of Endogenous Regional Growth: Lessons for Regional Policies,
Artige, Lionel ULiege; Nicolini, Rosella

in Journal of Regional Science (2003), 43(2), 403-406

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See detailDes organes juridictionnels en matière pénale pour l'Union euorpéenne
Flore, Daniel ULiege; de Biolley, Serge

in Cahiers de Droit Européen (2003)

L’idée de la création d’un espace européen de justice pénale est inscrite dans le Traité sur l’Union Européenne depuis Amsterdam et on peut être certain qu’elle sera maintenue dans la Constitution ... [more ▼]

L’idée de la création d’un espace européen de justice pénale est inscrite dans le Traité sur l’Union Européenne depuis Amsterdam et on peut être certain qu’elle sera maintenue dans la Constitution européenne actuellement en projet. Cette idée d’espace porte en elle plusieurs évolutions par rapport aux schémas de la coopération judiciaire classique. Parmi ces évolutions, certaines sont d’une nature telle qu’elles suscitent la question de la nécessité de l’instauration d’une fonction juridictionnelle autonome au niveau de l’Union européenne. [less ▲]

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See detailT-cell reconstitution after unmanipulated, CD8-depleted or CD34-selected nonmyeloablative peripheral blood stem-cell transplantation.
Baron, Frédéric ULiege; Schaaf-Lafontaine, Nicole ULiege; Humblet-Baron, Stéphanie ULiege et al

in Transplantation (2003), 76(12), 1705-13

BACKGROUND: We have previously shown that CD8 depletion or CD34 selection of peripheral blood stem cells (PBSC) reduced the incidence of acute graft-versus-host disease (GvHD) after nonmyeloablative stem ... [more ▼]

BACKGROUND: We have previously shown that CD8 depletion or CD34 selection of peripheral blood stem cells (PBSC) reduced the incidence of acute graft-versus-host disease (GvHD) after nonmyeloablative stem-cell transplantation (NMSCT). In this study, we analyze the effect of CD8 depletion or CD34 selection of the graft on early T-cell reconstitution. METHODS: Nonmyeloablative conditioning regimen consisted in 2 Gy total-body irradiation (TBI) alone, 2 Gy TBI and fludarabine, or cyclophosphamide and fludarabine. Patients 1 to 18 received unmanipulated PBSC, patients 19 to 29 CD8-depleted PBSC, and patients 30 to 35 CD34-selected PBSC. RESULTS: T-cell counts, and particularly CD4+ and CD4CD45RA+ counts, remained low the first 6 months after nonmyeloablative stem-cell transplantation (NMSCT) in all patients. CD34 selection (P<0.0001) but not CD8 depletion of PBSC significantly decreased T-cell chimerism. Donor T-cell count was similar in unmanipulated compared with CD8-depleted PBSC recipients but was significantly lower in CD34-selected PBSC recipients (P=0.0012). T cells of recipient origin remained stable over time in unmanipulated and CD8-depleted PBSC patients but expanded in some CD34-selected PBSC recipients between day 28 and 100 after transplant. Moreover, whereas CD8 depletion only decreased CD8+ counts (P<0.047), CD34 selection reduced CD3+(P<0.001), CD8+(P<0.016), CD4+ (P<0.001), and CD4+CD45RA+ (P<0.001) cell counts. T-cell repertoire was restricted in all patients on day 100 after hematopoietic stem-cell transplantation but was even more limited after CD34 selection (P=0.002). CONCLUSIONS: Despite of the persistence of a significant number of T cells of recipient origin, T-cell counts were low the first 6 months after NMSCT. Moreover, contrary with CD8 depletion of the graft that only affects CD8+ lymphocyte counts, CD34 selection dramatically decreased both CD8 and CD4 counts. [less ▲]

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See detailPseudo-hippocratisme digital: une entité à distinguer
Lizin, V. A.; Richert, Bertrand ULiege; de LA BRASSINNE, Michel ULiege

in Nouvelles Dermatologiques (2003), 22

Pseudo-clubbing is different in many respects from clubbing. Its causes are multiple, mechanical, tumoral of sometimes congenital, while clubbing occurs mostly in association with hypoxia. Pseudo-clubbing ... [more ▼]

Pseudo-clubbing is different in many respects from clubbing. Its causes are multiple, mechanical, tumoral of sometimes congenital, while clubbing occurs mostly in association with hypoxia. Pseudo-clubbing is also characterized by an increased transversal and longitudinal curvature of the nail plate but the other anatomic considerations associated with clubbing are not present. [less ▲]

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See detailModulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice.
MASSION, Paul ULiege; Balligand, J.-L.

in Journal of Physiology (2003), 546(Pt 1), 63-75

The modulatory role of endothelial nitric oxide synthase (eNOS) on heart contraction, relaxation and rate is examined in light of recent studies using genetic deletion or overexpression in mice under ... [more ▼]

The modulatory role of endothelial nitric oxide synthase (eNOS) on heart contraction, relaxation and rate is examined in light of recent studies using genetic deletion or overexpression in mice under specific conditions. Unstressed eNOS-/- hearts in basal conditions exhibit a normal inotropic and lusitropic function, with either decreased or unchanged heart rate. Under stimulation with catecholamines, eNOS-/- mice predominantly show a potentiation in their beta-adrenergic inotropic and lusitropic responsiveness. A similar phenotype is observed in beta 3-adrenoceptor deficient mice, pointing to a key role of this receptor subtype for eNOS coupling. The effect of eNOS on the muscarinic cholinergic modulation of cardiac function probably operates in conjunction with other NO-independent mechanisms, the persistence of which may explain the apparent dispensability of this isoform for the effect of acetylcholine in some eNOS-/- mouse strains. eNOS-/- hearts submitted to short term ischaemia-reperfusion exhibit variable alterations in systolic and diastolic function and infarct size, while those submitted to myocardial infarction present a worsened ventricular remodelling, increased 1 month mortality and loss of benefit from ACE inhibitor or angiotensin II type I receptor antagonist therapy. Although non-conditional eNOS gene deletion may engender phenotypic adaptations (e.g. ventricular hypertrophy resulting from chronic hypertension, or upregulation of the other NOS isoforms) potentially confounding the interpretation of comparative studies, the use of eNOS-/- mice has undoubtedly advanced (and will probably continue to improve) our understanding of the complex role of eNOS (in conjunction with the other NOSs) in the regulation of cardiac function. The challenge is now to confirm the emerging paradigms in human cardiac physiology and hopefully translate them into therapy. [less ▲]

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See detailFinding the lost Iris sofarana Foster
Saad, Layla ULiege

in Aril Society International Yearbook (2003)

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See detailInfluence Molecular Arrangement in Self-assembled Monolayers on Adhesion Forces Measured by Chemical Force Microscopy
Duwez, Anne-Sophie ULiege; Jonas, Ulrich; Klein, Hubert

in Chemphyschem : A European Journal of Chemical Physics and Physical Chemistry (2003), 4

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See detailSkin weathering and ashiness in black Africans.
Uhoda, Emmanuelle ULiege; Pierard, Claudine ULiege; Petit, Ludivine et al

in European Journal of Dermatology (2003), 13(6), 574-8

Ashiness describes a common physiological skin condition that may develop in people with dark skin complexion. Environmental influences, particularly cold and dry weather, seem obvious. This condition has ... [more ▼]

Ashiness describes a common physiological skin condition that may develop in people with dark skin complexion. Environmental influences, particularly cold and dry weather, seem obvious. This condition has seldom been studied so far. In the present study, skin ashiness was assessed in 37 black African women by means of colorimetric assessments and xerosis ratings. Colour changes were measured by the parameters a* and the individual typology angle ITA degrees. Xerosis was assessed by visual inspection, the ultraviolet light-enhanced visualization (ULEV) method, and the cyanoacrylate skin surface stripping (CSSS) method. The assessments were performed on ashy skin of the legs and on the normal looking forehead during the winter season. Ashy skin was lighter but not erythematous. The ITA-revealed colour changes were correlated with xerosis severity as assessed by dry dermoscopy and by the ULEV and CSSS methods. In conclusion, ashiness due to skin weathering does not appear to be related to mild inflammation. It corresponds to a peculiar type of xerosis with reduction in Fresnel reflection by the stratum corneum. [less ▲]

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See detailDevelopment and validation of a specific radioimmunoassay for equine osteocalcin
Carstanjen, Bianca; Sulon, Joseph ULiege; Banga-Mboko, H. et al

in Domestic Animal Endocrinology (2003), 24(1), 31-41

This study describes for the first time the development and validation of a sensitive and specific radioimmunoassay (RIA) for equine osteocalcin (OC) quantification using purified equine OC as standard ... [more ▼]

This study describes for the first time the development and validation of a sensitive and specific radioimmunoassay (RIA) for equine osteocalcin (OC) quantification using purified equine OC as standard, tracer, and immunogen for antibody formation in rabbits. The assay allowed to measure equine serum OC levels with a sensitivity of 0.2 ng/mL. Immunoreactive serum OC values of clinically normal, different-aged horses ranged from 3.68 to 127.31 ng/mL. Intra- and inter-assay coefficients of variation (CV) were 6.2 and 8.2%, respectively. Serial equine scrum sample dilutions were linear. The recovery of equine OC from equine serum samples ranged from 93.88 to 107.9%. There was a tight correlation between OC values measured with the equine- specific OC RIA and two commercially available bovine-specific OC RIA kits. However, highest serum OC values were obtained with the equine-specific OC RIA. In conclusion, our equine-specific OC RIA is sensitive, linear, accurate, precise, and reproducible. The assay allowed to quantify OC in equine serum samples and might, therefore, be used to monitor equine osteoblast activity associated with bone diseases, exercise, therapy forms or diet. [less ▲]

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See detailSylviculture et qualité du bois de l'épicéa en Région wallonne. Recommandations pratiques - Cahier technique n°22
Hebert, Jacques ULiege; Herman, M.; Jourez, B.

in Forêt Wallonne (2003), (62), 10-13

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See detailClassification des rongeurs
Mignon, Jacques ULiege; Hardouin, Jacques

in Bulletin BEDIM (2003), 12(1), 12-13

The note aims at providing the main characteristics of the principal families of rodents relevant to minilivestock.

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See detailFactor-XIIIa-positive dendrocytes in drug-induced toxic epidermal necrolysis (Lyell's syndrome): paradoxical activation in skin and rarefaction in lymph nodes.
Paquet, Philippe ULiege; Quatresooz, Pascale ULiege; Pierard, Gérald ULiege

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 206(4), 374-8

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell ... [more ▼]

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell infiltration. The precise pathomechanism of the disease remains unclear. METHODS: Skin specimens and peripheral and thoracic lymph nodes (LNs) were collected from 2 TEN patients. They were examined by conventional histology and immunohistochemistry using antibodies directed to factor XIIIa (dermal dendrocytes), CD1a (Langerhans cells), CD15 (granulocytes), CD20 (B lymphocytes), CD45RO (activated T lymphocytes), CD68 (macrophages) and the proliferation marker Ki-67. LNs from patients with mycosis fungoides, from subjects dead from acute cardiac failure or traumatic injuries, as well as metastasis-free sentinel LNs of cutaneous melanoma served as positive and negative controls. RESULTS: TEN LNs showed absence of germinal centers but a moderate hyperplasia of the paracortical T cell zone. Immunohistochemistry did not reveal any distinctive aspect in LN cellular densities between TEN and other control conditions except for the factor-XIIIa+ dendritic cells which were dramatically reduced in numbers in TEN LNs. This rarefaction in LNs contrasted with the great number of these cells in the skin of the same patients. CONCLUSION: The structure of TEN LNs rules out the involvement of an antibody-mediated response. As dendritic factor-XIIIa+ cells are involved in most cutaneous T-cell-mediated responses, their depletion in TEN LNs could explain the sparse lymphoid cell infiltrate in lesional TEN skin. [less ▲]

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See detailC.R. de La Chanson de Croissant en prose du XVe siècle (éd. M. Raby)
Henrard, Nadine ULiege

in Moyen Age (Le) (2003), CIX(3-4), 665-668

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See detailL’expérience politique des jeunes, par Anne Muxel (compte rendu)
Fournier, Bernard ULiege

in Politique et Sociétés (2003), 22(2)

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See detailL'herpèsvirus alcélaphin 1, l'agent responsable de la forme africaine du coryza gangreneux
Dewals, Benjamin G ULiege; Boudry, Christel ULiege; Markine-Goriaynoff, Nicolas ULiege et al

in Annales de Médecine Vétérinaire (2003), 147(1, FEB-MAR), 1-15

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the ... [more ▼]

Malignant catarrhal fever (MCF) is a pathology usually lethal which has been described in a large number of ruminant species. Based on the etiology, two main forms of MCF have been described, i.e., the European and the African forms due to ovine herpesvirus 2 (OvHV-2) and alcelaphine herpesvirus 1 (AlHV-1), respectively. The present review is devoted to the African form of MCF and to its causative agent AlHV-1. AlHV-1 belongs to the Gammaherpesvirinae subfamily of the Herpesviridae family. Wildebeests (Connochaetes spp) carry AlHV-1, which is lethal for a large number of ruminant species, while apparently harmless to its natural host. In hosts susceptible to MCF, the pathology is characterized by fever, extensive lymphadenopathy, ulcerative lesions of the digestive and the upper respiratory tracts mucous membranes and severe keratoconjunctivitis. In the present paper, we will review the data available to date on AlHV-1 and on the African form of MCF with emphasis on the pathogenesis, clinical signs and anatomo-pathological lesions of MCF. Finally, we will discuss the relationship between AlHV-1 and wildebeest as an example of symbiosis between a virus and its natural host. [less ▲]

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See detailAutocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM+) precursor cells from postnatal striatum.
Nguyen, Laurent ULiege; Malgrange, Brigitte ULiege; Breuskin, Ingrid ULiege et al

in Journal of Neuroscience (2003), 23(8), 3278-94

GABA and its type A receptor (GABA(A)R) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study, on ... [more ▼]

GABA and its type A receptor (GABA(A)R) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study, on the basis of their isopycnic properties in a buoyant density gradient, we developed an isolation procedure that allowed us to purify proliferative neural precursor cells from early postnatal rat striatum, which expressed the polysialylated form of the neural cell adhesion molecule (PSA-NCAM). These postnatal striatal PSA-NCAM+ cells were shown to proliferate in the presence of epidermal growth factor (EGF) and formed spheres that preferentially generated neurons in vitro. We demonstrated that PSA-NCAM+ neuronal precursors from postnatal striatum expressed GABA(A)R subunits in vitro and in situ. GABA elicited chloride currents in PSA-NCAM+ cells by activation of functional GABA(A)R that displayed a typical pharmacological profile. GABA(A)R activation in PSA-NCAM+ cells triggered a complex intracellular signaling combining a tonic inhibition of the mitogen-activated protein kinase cascade and an increase of intracellular calcium concentration by opening of voltage-gated calcium channels. We observed that the activation of GABA(A)R in PSA-NCAM+ neuronal precursors from postnatal striatum inhibited cell cycle progression both in neurospheres and in organotypic slices. Furthermore, postnatal PSA-NCAM+ striatal cells synthesized and released GABA, thus creating an autocrine/paracrine mechanism that controls their proliferation. We showed that EGF modulated this autocrine/paracrine loop by decreasing GABA production in PSA-NCAM+ cells. This demonstration of GABA synthesis and GABA(A)R function in striatal PSA-NCAM+ cells may shed new light on the understanding of key extrinsic cues that regulate the developmental potential of postnatal neuronal precursors in the CNS. [less ▲]

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See detailInstrumental investigations in primary headache. An updated review and new perspectives
Friberg, L.; Sandrini, G.; Janig, W. et al

in Functional Neurology (2003), 18(3, JUL-SEP), 127-144

While some instrumental techniques are clearly useful for differentiating symptomatic forms from primary headache, the usefulness of certain other techniques, neurophysiological investigations in ... [more ▼]

While some instrumental techniques are clearly useful for differentiating symptomatic forms from primary headache, the usefulness of certain other techniques, neurophysiological investigations in particular, in clinical practice is still debated. A Task Force of the European Federation of Neurological Societies has recently proposed guidelines and recommendations on the use of neurophysiological tests and neuroimaging procedures in non-acute headache. This article reviews many of the most important literature references relevant to this topic and looks at the prospects for future research. [less ▲]

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See detailCompte rendu de l'ouvrage de S. Dawans : Le spectre de la honte
Cormann, Grégory ULiege

in Archives de Philosophie (2003), 66(2), 340-342

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See detailPhysiology of reproduction and endocrinology in cervids. A review
Drion, Pierre ULiege; Hanzen, Christian ULiege; Wirth, Delphine - in memoriam et al

in Annales de Médecine Vétérinaire (2003), 147(5), 291-313

Knowledge about cervids are rapidly growing. This work aims to present the more recent scientific information on reproductive physiology and endocrinology of the cervids: anatomy of the genital tract ... [more ▼]

Knowledge about cervids are rapidly growing. This work aims to present the more recent scientific information on reproductive physiology and endocrinology of the cervids: anatomy of the genital tract, length of breeding season, parameters and endocrinology of the reproductive cycle, endocrinology of pregnancy. It also aims to highlight differences between cervids and domestic ruminants such as embryonic diapause observed in Capreolus capreolus. [less ▲]

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See detailDistinct T cell subsets and cytokine production in cultures derived from transformation zone and squamous intraepithelial lesion biopsies of the uterine cervix.
Jacobs, Nathalie ULiege; Renard, Isabelle; Al-Saleh, Walid et al

in American Journal of Reproductive Immunology (2003), 49(1), 6-13

PROBLEM: The characterization of lymphocytes issued from squamous intraepithelial lesions (SIL) and from the transformation zone (TZ), where the majority of SIL occur, is important to understand the role ... [more ▼]

PROBLEM: The characterization of lymphocytes issued from squamous intraepithelial lesions (SIL) and from the transformation zone (TZ), where the majority of SIL occur, is important to understand the role of immunity in SIL development. METHOD OF STUDY: We compared lymphocyte populations of the TZ and SIL with those of normal exocervix, using a technique allowing for the isolation of lymphocytes, either from the epithelium or from the underlying stroma of small biopsies. RESULTS: The majority of cells derived from the epithelium of all biopsies were CD8+ T cells. Some SIL-derived cultures were characterized by an increased proportion of activated TCRgammadelta+. The production of the immunosuppressive cytokine IL10 was significantly higher in lymphocyte cultures from the normal TZ in comparison with the exocervix. A decreased percentage of effector T cells was observed in cultures derived from the stroma of normal TZ (TCRgammadelta+) or SIL (CD8+) in comparison with the exocervix. CONCLUSIONS: Our results suggest that a low proportion of effector T cells and IL10 production could contribute to the predisposition of the TZ to the development of SIL and to the progression of SIL to cervical cancer. [less ▲]

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See detailLarge phosphorus hyperfine coupling as a sensitive tool for studying molecular dynamics : ESR and Molecular Mechanics studies of ring interconversion in cis-2,5-diphosphoryl-2,5-dimethyl-pyrrolidinoxyl radical
Rockenbauer, Antal; Gaudel-Siri, Anouk; Siri, Didier et al

in Journal of Physical Chemistry A (2003), 107(19), 3851-3857

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was ... [more ▼]

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was observed for t-1; however, for c-1, the inner lines of the 1:2:1 triplet showed a dramatic broadening characteristic of chemical exchange between two equivalent conformations. Owing to the large difference in the hyperfine splitting constants (hfsc) of the exchanging phosphorus (¢aP 21 G), the coalescence temperature was unusually high (193 K, in n-pentane), and the potential barrier for ring interconversion (10.5 kJ mol-1) was easily obtained from the temperature dependence of the exchange rate. This value was in very good agreement with the value obtained for an empirical pseudorotational potential (11 kJ mol-1) that was adjusted to fit the temperature dependence of the phosphorus hfsc. For c-1, molecular mechanics calculations gave similar characteristics for the pseudorotational potential and indicated the existence of two identical minima with distorted geometries lying between 3T4 and 3E or 4T3 and E3. For t-1, only the 3T4 conformer was found to be significantly populated. Frozen solution spectra showed that the phosphorus hfsc anisotropy is higher when the C-P bond is pseudoaxial; this result can be explained by a geometry-dependent delocalization of the unpaired electron into the phosphorus 3p orbitals. [less ▲]

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See detailUne recherche-action pour développer les capacités de compréhension de l’écrit en 1re accueil … Premier bilan
Schillings, Patricia ULiege; Poncelet, Débora

in Point sur la Recherche en Education (Le) (2003)

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See detailFestina lente: evidences for fast and slow learning processes and a role for sleep in human motor skill learning.
Maquet, Pierre ULiege; Laureys, Steven ULiege; Perrin, Fabien et al

in Learning & Memory (Cold Spring Harbor, N.Y.) (2003), 10(4), 237-9

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See detailPotato Tuber Phospholipids Contain Colneleic Acid In The 2-Position
Fauconnier, Marie-Laure ULiege; Williams, Td.; Marlier, M. et al

in FEBS Letters (2003), 538(1-3),

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See detailL'euthanasie en Belgique et aux Pays-Bas
Leleu, Yves-Henri ULiege

in Revue Trimestrielle des Droits de l'Homme (2003)

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See detailDetuning effects on the mazer
Martin, John ULiege; Bastin, Thierry ULiege

in Physicalia Magazine (2003), 25

A short review of the theoretical studies of the cold atom micromaser (mazer) is presented. Existing models are then improved by considering more general working conditions. Especially, the mazer physics ... [more ▼]

A short review of the theoretical studies of the cold atom micromaser (mazer) is presented. Existing models are then improved by considering more general working conditions. Especially, the mazer physics is investigated in the situation where a detuning between the cavity mode and the atomic transition frequency is present. Interesting new effects are pointed out. Especially, it is shown that the cavity may slow down or speed up the atoms according to the sign of the detuning and that the induced emission process may be completely blocked by use of a positive detuning. The transmission probability of ultracold atoms through a micromaser is also studied and we generalize previous results established in the resonant case. In particular, it is shown that the velocity selection of cold atoms passing through the micromaser can be very easily tuned and enhanced using a nonresonant field inside the cavity. [less ▲]

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See detailSelection of the most efficient wavelength bands for 'Jonagold' apple sorting
Kleynen, O.; Leemans, Vincent ULiege; Destain, Marie-France ULiege

in Postharvest Biology & Technology (2003), 30(3), 221-232

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system ... [more ▼]

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system. Reflectance spectra of damaged and sound tissue were recorded using a visible/NIR spectrometer. Analysed defects consisted of scald, hail damage (with and without skin perforation), limb rubs, russets, scab tissue, frost damage, rot, visible flesh damage and recent bruises. Camera filter effects were approximated by summing the reflectances of all the wavelengths within the filter bandwidth. Combinations of three and four filters were tested and evaluated for discriminating damaged tissues from healthy ones. If a three-filter combination appeared sufficient to detect most of the damaged tissue, a four-filter combination should be considered for the complete sorting automation of this bicolour apple variety. A fourth filter was necessary to quantify the ratio between the blush and ground colours. Regarding recent bruise defects which represented the major difficulty, an image segmentation algorithm based on local contrast variations can enhance their detection. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailFrom the germinal cells to the newborn animal: The transmission of genes and life through the generations
Drion, Pierre ULiege; Szenci, Otto; Ectors, Fabien ULiege et al

in Acta Veterinaria Hungarica (2003), 51(3), 371-384

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most ... [more ▼]

The technology of reproduction progressed considerably during the last decade, leading to a certain availability of in vitro methods for fertilisation, oocyte maturation and embryo culture. The most spectacular manipulations are cloning and transgenesis. This review focuses on the early appearance of germinal cell precursors and the long-standing fate of gametes in mammals. The evident complexity and long-term programming of events in gametes and early embryos explain part of the difficulties encountered during the development of in vitro and in vivo methods such as multiple Ovulation and embryo transfer (MOET), oestrus synchronisation, ovulation induction, superovulation, in vitro maturation and fertilisation, cryopreservation, transgenesis, nuclear transfer and cloning) and the occurrence of unexpected alterations of development, e.g. embryonic or fetal mortality, large-weight newborn syndrome and other dysregulations ill imprinting or DNA transmission. [less ▲]

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See detailMetabolising risk: food scares and the un/re-making of Belgian beef
Stassart, Pierre M ULiege; Whatmore, Sarah J.

in Environment & Planning A (2003), 35

In this paper we explore the event of foodscares as an example of what Callon calls 'hot situations', in which the landscape of competing knowledge claims is at its most molten, and alternative production ... [more ▼]

In this paper we explore the event of foodscares as an example of what Callon calls 'hot situations', in which the landscape of competing knowledge claims is at its most molten, and alternative production and consumption practices galvanise new modes of sense-making against the market and state-sanctioned rationalities of industrialisation. Through a case study of the Belgian cooperative Coprosain and its meat products, we examine the 'stuff' of food as a ready messenger of connectedness and affectivity in which 'risk' is transacted as a property both of the growing distance between the spaces of production and consumption and of the enduring metabolic intimacies between human and nonhuman bodies. [less ▲]

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See detailL'enseignement en Communauté française : un haut degré d'iniquité
Baye, Ariane ULiege; Nicaise, Julien; Straeten, Marie-Hélène et al

in Espace de Libertés : Magazine du Centre d'Action Laïque (2003), (316), 16-17

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See detailComparative clinical and electrometric assessments of the impact of surfactants on forearm skin.
Uhoda, Emmanuelle ULiege; Paye, Marc; Pierard, Gérald ULiege

in Exogenous Dermatology : Physical, Chemical, Biological (2003), 2

Surfactant-based skin care products can induce minimal to more severe alterations to human stratum corneum (SC). These changes can be conveniently assessed using electrometric devices. Four different ... [more ▼]

Surfactant-based skin care products can induce minimal to more severe alterations to human stratum corneum (SC). These changes can be conveniently assessed using electrometric devices. Four different surfactant-based solutions were applied on the forearms of 10 healthy volunteers following a soap chamber test method. The 2-day patch testing was followed by a 2-week follow-up. Clinical and instrumental assessments were performed at 7 time points. Data generated by the Corneometer® CM820, the DermaLab Moisture Module® and the Nova Dermal Phase Meter (DPM)® 9003 were compared. The significant differences between the product aggressiveness to the SC were similarly disclosed by the Corneometer® and the DermaLab Moisture Module®. The ranking of product aggressiveness given by the 3 devices 5 days after patch removal was similar to that given by the clinical assessment of erythema. A high level of correlation were found between the values yielded by the immediate and continuous mode assessments using the DermaLab Moisture Module with the Pin Probe, while the correlation was weaker with the Nova DPM®. This finding may be related to the fact that the Nova DPM is influenced by the accumulation of the transepidermal water loss in the continuous mode assessment while there is no significant occlusion effect of the DermaLab Moisture® Pin Probe that is more representative of the initial level of SC hydration. In conclusion, the Corneometer® and the DermaLab Moisture Module® respond similarly to changes in the SC content. This finding is different from some previous reports. [less ▲]

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See detailLe Musée en Piconrue de Bastogne
Donneau, Olivier ULiege

in Invitation au musée : Courrier du patrimoine culturel de la Communauté française (2003), 4

Courte présentation des activités du Musée en Piconrue de Bastogne.

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See detailL'image du mois. Myiase furonculoide americaine.
Leonard, Philippe ULiege; Martalo, O.; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(12), 721-2

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See detailLe point sur la place du Robinier en Hongrie
Fourbisseur, Anne; Charron, Stéphane; Jourez, Benoît ULiege et al

in Forêt Wallonne (2003), (67), 26-30

Le robinier est une des deux essences les plus importantes en Hongrie1-2. Ce pays est mondialement reconnu comme chef de file pour la gestion de la ressource en robinier, depuis la <br />recherche en ... [more ▼]

Le robinier est une des deux essences les plus importantes en Hongrie1-2. Ce pays est mondialement reconnu comme chef de file pour la gestion de la ressource en robinier, depuis la <br />recherche en amélioration génétique jusqu’à la valorisation industrielle de son bois. Cet article se propose de faire la synthèse des connaissances acquises en Hongrie sur le développement de la <br />filière bois du robinier. L’objectif est de partager l’expérience hongroise avec ceux qui intéressent à cette essence à haut potentiel. Un bref historique de l’implantation du robinier dans ce pays sera exposé et suivi de l’état actuel de la ressource et d’une présentation succincte <br />des caractéristiques climatiques et édaphiques propres à la Hongrie. La sylviculture propre au robinier sera détaillée et les principales utilisations des produits ligneux seront décrites. Cette ynthèse s’achèvera avec la présentation de la collaboration sur le thème du robinier conclue <br />entre la Région wallonne, la Communauté française de Belgique et la République de Hongrie. [less ▲]

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See detailJean Michel-Bonvin : Figures de sociologues. Introduction à l'epistémologie sociologique
Jacquemain, Marc ULiege

in Schweizerische Zeitschrift für Soziologie = Revue Suisse de Sociologie (2003), 29

Jean-Michel Bonvin introduces the reader to the sociological method through the study of eight classical sociologists throught the 19th and 20th centurites : Comte, Tocqueville, Marx, Durkheim, Weber ... [more ▼]

Jean-Michel Bonvin introduces the reader to the sociological method through the study of eight classical sociologists throught the 19th and 20th centurites : Comte, Tocqueville, Marx, Durkheim, Weber, Simmel, Goffman and Parsons [less ▲]

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See detailNa-23 2D 3QMAS NMR and Si-29, Al-27 MAS NMR investigations of Laponite and synthetic saponites of variable interlayer charge
Delevoye, Laurent; Robert, Jean-Louis; Grandjean, Jean ULiege

in Clay Minerals (2003), 38

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See detailPrevention cardio-vasculaire par les statines: faut-il encore doser le cholesterol?
Scheen, André ULiege; Kulbertus, Henri ULiege

in Revue Médicale de Liège (2003), 58(4), 191-7

Statins, the most popular lipid-lowering agents, have proven their efficacy in preventing cardiovascular events in subjects with lower and lower initial plasma cholesterol levels. Besides, the protective ... [more ▼]

Statins, the most popular lipid-lowering agents, have proven their efficacy in preventing cardiovascular events in subjects with lower and lower initial plasma cholesterol levels. Besides, the protective effect does not seem to be directly related neither to the degree of the cholesterol reduction nor to the final level of plasma cholesterol level reached under treatment. Such observations suggest that statins may exert vascular protective effects, at least in part, independently of their specific cholesterol-lowering effect (so-called pleiotropic effects). The present paper will discuss the arguments pro and contra the dosage of cholesterolaemia before initiating a therapy with statin and during treatment follow up, both in subjects with previous cardiovascular events (secondary prevention) and in subjects with a high cardiovascular absolute risk but without previous clinical expression of atherosclerosis (primary prevention). [less ▲]

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See detailA low rate of trisomy 21 in twin-pregnancies: A cytogenetics retrospective study of 278 cases
Jamar, Mauricette ULiege; Lemarchal, C.; Koulischer, Lucien ULiege et al

in Genetic Counseling (2003), 14(4), 395-400

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See detailLes effets de la formation professionnelle continue : une enquête auprès des bénéficiaires des actions du Fonds social européen en Wallonie et à Bruxelles
Conter, Bernard; Maroy, Christian; Orianne, Jean-François ULiege

in Politiques d'Education et de Formation : Analyses et Comparaisons Internationales (2003), 7

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See detailJansénisme et monachisme féminin aux pays de Liège et de Luxembourg
Henneau, Marie-Elisabeth ULiege

in Chroniques de Port-Royal (2003), 52

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See detailCitizenship and Migration - S. Castles and A. Davidson
Martiniello, Marco ULiege

in International Sociology (2003), 18(2), 417-418

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See detailReal sex in bacteria !
Gratia, Jean-Pierre; Thiry, Marc ULiege

in Microbiology Today (2003), 30

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See detailLoi du 2 août 2002 concernant la lutte contre le retard de paiement dans les transactions commerciales
Decharneux, Joëlle ULiege

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailUltradispersity of diamond at the nanoscale
Raty, Jean-Yves ULiege; Galli, G.

in Nature Materials (2003), 2(12), 792-795795

Nanometre-sized diamond has been found in meteorites, protoplanetary nebulae, and interstellar dusts, as well as in residues of detonation and in diamond films. Remarkably, the size distribution of ... [more ▼]

Nanometre-sized diamond has been found in meteorites, protoplanetary nebulae, and interstellar dusts, as well as in residues of detonation and in diamond films. Remarkably, the size distribution of diamond nanoparticles seems to be peaked around 2-5 nm, and to be largely independent of preparation conditions. We have carried out ab initio calculations of the stability of nanodiamond as a function of surface hydrogen coverage and of size. We have found that at about 3 nm, and for a broad range of pressures and temperatures, particles with bare, reconstructed surfaces become thermodynamically more stable than those with hydrogenated surfaces, thus preventing the formation of larger grains. Our findings provide an explanation of the size distribution of extraterrestrial and of terrestrial nanodiamond found in ultradispersed and ultracrystalline diamond films. They also provide an atomistic structural model of these films, based on the topology and structure of 2-3 nm diamond clusters consisting of a diamond core surrounded by a fullerene-like carbon network [less ▲]

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See detailFitting lactation curves of dairy cattle in different types of herds in Tunisia
Rekik, Boulbaba; Ben Gara, Abderrahmen; Ben Hamouda, Mohamed et al

in Livestock Production Science (2003), 83(2-3), 309-315

The incomplete gamma function was used to fit lactation curves of Holstein-Friesian cows in four types of herds in Tunisia. A total of 8640 records were used in the analysis. These included 1269, 637, 239 ... [more ▼]

The incomplete gamma function was used to fit lactation curves of Holstein-Friesian cows in four types of herds in Tunisia. A total of 8640 records were used in the analysis. These included 1269, 637, 239, and 498 first lactation and 2986, 1441, 650, and 920 second and later lactation records in four herd groups namely investors, state, cooperative, and farmers' herds, respectively. The effects of environmental variables, production sector, herd, parity, first test-day date, calving year, and calving season on the main lactation curve traits were analysed. The factors associated with milk yield at the beginning of lactation and the decreasing phase of the curve, persistency, and peak yield varied significantly (P<0.01) with all variables. The ascending phase of the lactation curve was not affected by parity and calving year, while days in milk until peak depended only on the rank of lactation. The state herds had the lowest peak and total yields. The summer season was unfavourable for milk production. In contrast to first lactation cows, third lactation cows had the highest peak and total yields. Milk yield was highly correlated with peak yield (r = 0.79) and was not related to persistency measure. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailL'urticaire et ses implications systémiques
Dezfoulian, Bita ULiege; Khalil, Z.; de LA BRASSINNE, Michel ULiege

in Revue Médicale de Liège (2003), 58(12), 751-756

Urticaria is a transient eruption of erythematous or oedematous swelling of the dermis and is usually associated with itching which clinically is very easy to diagnose. However, it causes several ... [more ▼]

Urticaria is a transient eruption of erythematous or oedematous swelling of the dermis and is usually associated with itching which clinically is very easy to diagnose. However, it causes several etiological, pathophysiological and therapeutic problems. We will develop the acute and chronic urticaria as well as their different associations with systemic diseases. Some current data concerning chronic idiopathic autoimmune urticaria is reviewed. The management and therapeutics will be discussed. [less ▲]

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See detailBlending of hydrogenated low-erucic acid rapeseed oil, low-erucic acid rapeseed oil, and hydrogenated palm oil or palm oil in the preparation of shortenings
Danthine, Sabine ULiege; Deroanne, Claude ULiege

in Journal of the American Oil Chemists' Society (2003), 80(11), 1069-1075

Two ternary systems of fats were studied. In the first system, low-erucic acid rapeseed oil (LERO), hydrogenated low-erucic acid rapeseed oil (HLERO), and palm oil (PO) were blended. In the second system ... [more ▼]

Two ternary systems of fats were studied. In the first system, low-erucic acid rapeseed oil (LERO), hydrogenated low-erucic acid rapeseed oil (HLERO), and palm oil (PO) were blended. In the second system, hydrogenated palm oil (HPO) was used instead of PO and was blended with LERO and HLERO. The blends were then studied for their physical properties such as solid fat content (SFC), melting curves by DSC, and polymorphism (X-ray). HPO showed the highest melting enthalpy after 48 h at 15degreesC (141 +/- 1 J/g), followed by HLERO (131 +/- 2 J/g), PO (110 +/- 2 J/g), and LERO (65 +/- 4 J/g). Binary phase behavior diagrams were constructed from the DSC and X-ray results. Iso-line diagrams of partial-melting enthalpies were constructed from the DSC results, and binary and ternary isosolid diagrams were constructed from the NMR results. The isosolid diagrams demonstrated formation of a eutectic along the binary blend of PO/HLERO. However, no eutectic effect was observed along the binary lines of HPO/HLERO, PO/LERO, HPO/LERO, or HLERO/LERO. The same results were found with the iso-line diagrams of partial-melting enthalpies. As expected, addition of PO or HPO increased polymorphic stability in the beta' form of the HLERO/LERO mixture. [less ▲]

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See detailThe frame problem in cognitive modeling
Anselme, Patrick ULiege

in Cognitive Science Quarterly (2003), 3(3), 329-350

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See detailQuelle formation andragogique pour les enseignants universitaires demain ?
Schmitz, Serge ULiege

in Actes du Geoforum (2003), 27

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See detailEpidemiology, clinical presentation and diagnostic strategy of gastro-esophageal reflux
Louis, Edouard ULiege

in Acta Endoscopica (2003), 33

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See detailLa pustulose sous-cornee de Sneddon et Wilkinson.
Martalo, O.; Paquet, Philippe ULiege; Pierard, Gérald ULiege

in Revue Médicale de Liège (2003), 58(10), 628-30

The subcorneal pustular dermatosis of Sneddon and Wilkinson belongs to the heterogeneous group of neutrophilic dermatosis. This unique disorder is characterized by a superficial pustular eruption. The ... [more ▼]

The subcorneal pustular dermatosis of Sneddon and Wilkinson belongs to the heterogeneous group of neutrophilic dermatosis. This unique disorder is characterized by a superficial pustular eruption. The pustules are flaccid and aseptic. They develop predominantly on the trunk and in the groins, axillae and submammary areas. This disease is benign and chronic. However, it can be associated with some other conditions such as lymphoproliferative and myeloproliferative diseases. Dapsone is the treatment of choice to control the skin manifestations. [less ▲]

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See detailRétention gazeuse dans une colonne à bulles contenant un liquide visqueux non-newtonien
Fransolet, Emmanuelle; Coumont, V.; Crine, Michel ULiege et al

in Tribune de l'Eau (La) (2003), 56(622), 15-20

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See detailCaractérisation génotypique de souches invasives aviaires d'Escherichia coli isolées en Belgique
Stordeur, P.; Beaupain, N.; Mainil, Jacques ULiege

in Annales de Médecine Vétérinaire (2003), 147(4, AUG-SEP), 275-280

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See detailOvero lethal white syndrome - two case reports and a review of the litterature
Sandersen, Charlotte ULiege; Delguste, Catherine ULiege; Cassart, Dominique ULiege et al

in Annales de Médecine Vétérinaire (2003), 147(5, OCT-NOV), 359-364

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See detailMycoplasma bovis : synthèse des connaissances actuelles
Thomas, Anne; Mainil, Jacques ULiege; Linden, Annick ULiege

in Annales de Médecine Vétérinaire (2003), 147(1, FEB-MAR), 23-39

Mycoplasmas frequently infect cattle. Amongst them, M. Bovis is the most pathogenic species in countries free from contagious bovine pleuropneumonia because it is responsible for bronchopneumonia ... [more ▼]

Mycoplasmas frequently infect cattle. Amongst them, M. Bovis is the most pathogenic species in countries free from contagious bovine pleuropneumonia because it is responsible for bronchopneumonia, arthritis and mastitis, and is thus associated with strong economic losses. Several studies have shown the frequency of M. bovis in Europe and the spread of antibiotic-resistant strains. Considering the absence of vaccine in Europe, it is essential to understand this bacteria in order to control the infection in cattle. In this context, this paper aims at summarizing the current knowledge about M. bovis. [less ▲]

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See detailSedimentary deposition rates and carbon-14: The epi-paleolithic sequence of Okuzini Cave (southwest Turkey)
Otte, Marcel ULiege; López Bayón, Ignacio; Noiret, Pierre ULiege et al

in Journal of Archaeological Science (2003), 30(3), 325-341

A series of radiocarbon dates systematically obtained from bone and charcoal samples from the stratigraphic sequence of Okuzini Cave has been analyzed in conjunction with stratigraphic and archaeological ... [more ▼]

A series of radiocarbon dates systematically obtained from bone and charcoal samples from the stratigraphic sequence of Okuzini Cave has been analyzed in conjunction with stratigraphic and archaeological data to interpret the rates and processes of deposition and human occupation of the cave during the Epipaleolithic of southwest Turkey. AMS dates obtained on the charcoal series reveal the existence of three stratigraphic gaps. Sedimentation rates for the deposits are evaluated in relation to radiometric determinations, the nature and origin of sediment accumulation, the structure of the faunal and lithic assemblages and the changing nature of human occupation of the cave. A hypothesis is proposed to explain the processes and rates of sedimentation, including the three gaps revealed by the radiometric series. One of our aims is to caution against interpretations of cultural evolution directly linked to sedimentary rates for which the variation is not immediately evident during excavation, but which requires a more critical analysis, as we have had the opportunity to do at Okuzini. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailFacteurs de virulence et propriétés spécifiques des souches invasives d'Escherichia coli : I) les adhésines et facteurs de colonisation
Mainil, Jacques ULiege

in Annales de Médecine Vétérinaire (2003), 147(2, APR-MAY), 105-126

Escherichia coli bacterial species is subdivided into several strains that are pathogenic for man and animals, on the basis of their specific properties and factors which are responsible for their ... [more ▼]

Escherichia coli bacterial species is subdivided into several strains that are pathogenic for man and animals, on the basis of their specific properties and factors which are responsible for their pathogenic characters. The pathogenic strains are classically subdivided into strains with intestinal tropism (enterotoxigenic, enteropathogenic, enterohaemmorrhagic, verotoxigenic and enteroinvasive) and with extraintestinal tropism (uropathogenic and invasive). Invasive strains cause septicaemia and/or bacteraemia with localisations in different internal organs (systemic infections): If specific virulence properties and factors of strains with intestinal tropism are quite well known and described, those of strains with extraintestinal tropism are much less characterised, especially in animals. The purpose of this serie of review articles is to present the current knowledge on specific properties and factors of extraintestinal strains: adhesins and colonisation factors, transmucosal transfer and survival in blood and internal organs, toxicity. The fourth manuscript will deal with the invasive strains themselves, focusing on the necrotoxigenic strains. This first manuscript presents the current knowledge on the receptors, roles in pathogenesis, structures, genetic determinism and identification methods of fimbrial adhesins of P (Pap, Prs), S (Sfa, F1C, Sfr) and F17 (Vir, Att25, FY, 20K, G, Att111) families and of afimbrial adhesins of Afa family (Afa, Nfa, F1845, Bma, Dr...). [less ▲]

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See detailRilke herlezen
Spinoy, Erik ULiege

in Freespace Nieuwzuid (2003), 3(12), 80

In this special issue, a number of critics reflect on the question if and how it is still possible today to take great lyrical poetry at face value. The case at hand is that of Rilke's Duino Elegies.

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