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See detailEctopie cervicale du coeur chez un veau
Gabriel, Annick ULg; Vandeputte, Sébastien ULg; Rollin, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1994), 138

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See detailSuccessful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
Snoeck, R.; Andrei, G.; Gerard, Marie-Christine ULg et al

in Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America (1994), 18(4), 570-8

The acyclic nucleoside phosphonate (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was used topically for the treatment of persistent mucocutaneous infections in two cases. One patient with ... [more ▼]

The acyclic nucleoside phosphonate (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was used topically for the treatment of persistent mucocutaneous infections in two cases. One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to acyclovir and was intolerant of foscarnet. A bone marrow transplant recipient developed orofacial lesions due to infection with herpes simplex virus type 1 (HSV-1) that failed to respond to therapy with both acyclovir and foscarnet. After topical application of HPMPC, the HSV-2 lesions completely resolved. However, the lesions recurred 3 weeks later, and, upon subsequent treatment with HPMPC, regressed. On recurrence, the virus was found to be sensitive to acyclovir, which the patient was given. Again HSV-2, which was resistant to acyclovir, emerged; similar observations were made after another cycle of HPMPC therapy. The HSV-1 isolates were resistant to acyclovir and foscarnet. Following local HPMPC treatment, the lesions regressed, but after 1 week, a second course of topical HPMPC therapy had to be instituted for recurrent infection. The lesions again regressed, and as the recurrent virus was sensitive to acyclovir, the patient was successfully treated with the drug. The results of this study point to the potential usefulness of topical HPMPC in the treatment of immunocompromised patients with HSV-related mucocutaneous infections that are refractory to therapy with acyclovir and/or foscarnet. [less ▲]

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See detailPreliminary of observations on oribatid mites of riparian soils in Uruguay
Sarasola, M.; Vera, H.; Wauthy, G. et al

in Bulletin et Annales de la Société Royale Belge d’Entomologie = Bulletin en Annalen van de Koninklijke Belgische Vereniging voor Entomologie (1994), 130

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See detailEpidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools.
Knapen, K.; Kerkhofs, P.; Thiry, Etienne ULg et al

in Epidemiology & Infection (1994), 113(3), 563-9

Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of ... [more ▼]

Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of 145 serum pools, comprising from 3 to 48 individual sera. The sample was constituted according to the frequency distribution of the negative and positive pools analysed during a screening involving the whole cattle population of Belgium. Sensitivity and specificity were estimated to 88.9% and 100% and the predicted negative and positive values were 99.9% and 100%, respectively. These results indicate the use of serum pools is suitable for the detection of BLV infected herds in eradication campaigns. [less ▲]

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See detailEfficacité de la radiothérapie pour le traitement des récidives en gynécologie oncologique
COUCKE, Philippe ULg; Sartorelli, B

in Revue Médicale de la Suisse Romande (1994), 114(9), 799-804

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See detailTransient hypersensitivity to apomorphine-induced gnawing after termination of acute effects high dose of cocaine
Tirelli, Ezio ULg; Witkin, J. M.

in Behavioural Pharmacology (1994), 5(3), 289-298

Male mice were tested for behavioral effects (BEs) of the dopamine (DA) agonist apomorphine (AP) at various times after acute administration of cocaine (COC). When most of the COC had disappeared from ... [more ▼]

Male mice were tested for behavioral effects (BEs) of the dopamine (DA) agonist apomorphine (AP) at various times after acute administration of cocaine (COC). When most of the COC had disappeared from brain and the BEs of COC had dissipated (2 hrs and 4 hrs after administration), effects of AP on gnawing were increased 4-fold. This dopaminergic hypersensitivity (DA-H) was induced by acute treatment with doses of 15 mg/kg COC and higher. Effects of AP were not enhanced 6-24 hrs after COC, indicating a rapid waning of the DA-H. Hypersensitivity to AP (AP-H) was not further augmented by 8 days of daily COC injections. COC did not influence climbing and hypomotility induced by AP 4 hrs after its injection, demonstrating selectivity in the BEs of the DA-H. Further, COC did not induce sensitization to its own effects, indicating that the AP-H was not due to a typical sensitization phenomenon. ((c) 1997 APA/PsycINFO, all rights reserved) [less ▲]

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See detailL'identité wallonne saisie par l'enquête : une approche constructiviste de l'identité collective
Jacquemain, Marc ULg; Vandekeere, Michel; Doutrelepont, René

in Res Publica (1994), 26

The paper shows how a constructivist approach of collective identity makes sense of the use of survey data to approach regional walloon identity

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See detailInactivation of alpha(2)-Macroglobulin by Activated Human Polymorphonuclear Leukocytes.
Deby, Ginette ULg; Croisier, Jean-Louis ULg; Camus, Gérard et al

in Mediators of Inflammation (1994), 3(2), 117-23

The proteolytic activity of trypsin releases the dye Remazol Brilliant Blue from its high molecular weight substrate, the skin powder (Hide Powder Azure, Sigma), with an increase in absorbance at 595 nm ... [more ▼]

The proteolytic activity of trypsin releases the dye Remazol Brilliant Blue from its high molecular weight substrate, the skin powder (Hide Powder Azure, Sigma), with an increase in absorbance at 595 nm. Active alpha(2)- macroglobulin (80 mug/ml) totally inhibits the proteolytic activity of trypsin (14 mug/ml) by trapping this protease. But after a 20 min incubation of alpha(2)-macroglobulin at 37 degrees C with 2 x 10(6) human polymorphonuclear leukocytes activated by N-formyl-L-methionyl-L-leucyl-L-phenylalanine (10(-7) M) and cytochalasin B (10(-8) M), 100% of trypsin activity was recovered, indicating a total inactivation of alpha(2)-macroglobuHn. Incubation with granulocyte myeloperoxidase also inactivates alpha(2)-macroglobulin. Hypochlorous acid, a by-product of myeloperoxidase activity, at a concentration of 10(-7) M also inactivates alpha(2)-macroglobulin, which indicates that an important cause of alpha(2)-macroglobulin inactivation by activated polymorphonuclear leukocytes could be the activity of myeloperoxidase. [less ▲]

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See detailA thyroid hormone receptor-dependent glucocorticoid induction.
Leers, Joerg; Steiner, Christoff; Renkawitz, Rainer et al

in Molecular Endocrinology (Baltimore, Md.) (1994), 8(4), 440-7

Glucocorticoid and thyroid hormones exert their effects in many body tissues by binding to their respective receptors. The search for possible cross-talking mechanisms in overlapping target cells led to ... [more ▼]

Glucocorticoid and thyroid hormones exert their effects in many body tissues by binding to their respective receptors. The search for possible cross-talking mechanisms in overlapping target cells led to the discovery of synergism between a thyroid hormone receptor-binding site and a cryptic glucocorticoid-responsive element. Glucocorticoid responsiveness could only be detected in the presence of thyroid hormone and its receptor. This synergism requires the glucocorticoid receptor (GR) DNA-binding domain and is mediated by the transactivation domains. We found that synergism also occurs when the thyroid hormone receptor is replaced by the retinoic acid receptor or the GR is replaced by the progesterone receptor. Synergism is qualitatively independent of the type of thyroid hormone receptor-binding site and promoter. In several combinations of promoter and response elements, including a retinoic acid response element, T3 induction was only seen in the presence of the cryptic glucocorticoid-responsive element, GR, and glucocorticoids. [less ▲]

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See detailWorking memory in Down's syndrome: Training the rehearsal strategy
Comblain, Annick ULg

in Down's Syndrome, Research and Practice : The Journal of the Sarah Duffen Centre (1994), 2(3), 123-126

This study reports on the verbal short term memory skills of individuals with Down's syndrome and on the possibility of increasing memory span durably by using a rehearsal strategy

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See detailModèles de cubage pour essences multi-tiges: application à des plantations d'acacia.
Lejeune, Philippe ULg; Rondeux, Jacques ULg

in Cahiers Agricultures (1994), 3(3),

Des tarifs de cubage individuels ont été construits pour estimer le volume de plantations d'Acacia auriculiformis A. Cunn. ex Benth destinées à la production de bois de feu. Ces tarifs fournissent, d'une ... [more ▼]

Des tarifs de cubage individuels ont été construits pour estimer le volume de plantations d'Acacia auriculiformis A. Cunn. ex Benth destinées à la production de bois de feu. Ces tarifs fournissent, d'une part, le volume total incluant le bois de tiges et de branches jusqu'à une découpe de 9 cm de circonférence et, d'autre part, ce volume réparti en classes de circonférences de 9 à 14 cm, 15 à 44 cm et plus de 45 cm. Cette essence est généralement abondamment ramifiée, ce qui complique la détermination de son volume et interfère avec la caractérisation d'une variable dendrométrique déterminante, à savoir la circonférence ou le diamètre à 1,30m au-dessus du niveau du sol. Lorsque plusieurs tiges sont observées à 1,30m de hauteur, il est proposé de considérer une circonférence théorique résultant de la somme quadratique des circonférences des brins mesurés à ce niveau. Différentes équations de cubage mettant en oeuvre les circonférences à la base de l'arbre (niveau d'abattage) ou à 1,30m, ainsi que la hauteur totale, l'âge et le nombre de brins, sont proposées pour des plantations âgées de quelques dizaines de mois. En termes de compromis entre précision des estimations et coût des mesures, l'équation faisant intervenir la circonférence à 1,30m, l'âge et le nombre de brins s'est avérée la plus satisfaisante. En ce qui concerne les estimations de volume par assortiments, applicables à des plantations plus âgées, les équations ne faisant intervenir que la seule circonférence à 1,3m sont largement acceptables. [less ▲]

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See detailSequence-Analysis Of A 40.2-Kb Dna Fragment Located Near The Left Telomere Of Yeast Chromosome-X
Vandenbol, Micheline ULg; Durand, Patrick; Bolle, P. A. et al

in Yeast (1994), 10(12),

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See detailEvaluation du débit sanguin lors de contractions volontaires et évoquées électriquement
Vanderthommen, Marc ULg; Depresseux, J.C.; BAUVIR, Philippe ULg et al

in Kiné 2000 (1994), 5

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See detailBacillus subtilis as a biopesticide : biochemical and technological aspects
Thonart, Philippe ULg; Heuze, V.; Destain, Jacqueline ULg et al

in Progress in biotechnology (1994), 9

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See detail2,7-dihydroapogeissoschizine from root bark of strychnos Gossweileri
Quetin-Leclercq, Joëlle; Dive, Georges ULg; Delaude, Clément et al

in Phytochemistry (1994), 35(2), 533-536

In this paper, we describe the isolation and structural determination of 2,7-dihydroxyapogeissoschizine, a new alkaloid from the root bark of Strychnos gossweileri. Elucidation of its structure is based ... [more ▼]

In this paper, we describe the isolation and structural determination of 2,7-dihydroxyapogeissoschizine, a new alkaloid from the root bark of Strychnos gossweileri. Elucidation of its structure is based mainly on 1D and 2D NMR studies; its conformation was optimized by energy minimization. This type of skeleton is related to geissoschizine but with the notable diffrence that the 1 and 17 positions are joined giving an additional fused ring. Such a seven-membered ring has ,to our knowledge, only been observed in apogeissoschizine, obtained after chemical tratment of two alkaloids ( geissospermine and geissoschizine). 2,7-dihydroxyapogeissoschizine is therefore, the first natural product possessing this skeleton. According to a preliminary test, this new alkaloid shows low toxicity to B16 melanoma cells, but not for non-cancer 3T3 fibroblasts cultured in vitro.THese results have to be confirmed by further tests. [less ▲]

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See detailA screening technique to isolate bacterial strains producing high molecular weight bacteriocins
Jabrane, A.; Destain, Jean-Pierre ULg; Compère, Philippe ULg et al

in Biotechnology Techniques (1994), 8(10), 751-754

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See detailRound Table Conference on Mediators of Sepsis--Brussels, Belgium, March 21-23, 1992
Lamy, Maurice ULg; Thijs, L. G.

in Intensive Care Medicine (1994), 20(3), 238-41

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See detailAssessment of the new immunological test Hemoblot for detecting occult blood in faeces
Jeanson, Antoinette; Jamart, J.; Maisin, J. M. et al

in European Journal of Cancer Prevention (1994), 3(5), 407-412

Hemoblot, a new immunological faecal occult blood test, produced by Gamma, Angleur, Belgium, was characterized and compared with another immunological test (HemeSelect, SmithKline Diagnostics, USA) and ... [more ▼]

Hemoblot, a new immunological faecal occult blood test, produced by Gamma, Angleur, Belgium, was characterized and compared with another immunological test (HemeSelect, SmithKline Diagnostics, USA) and with a guaiac test (Hemoccult II, SmithKline Diagnostics). The analytical sensitivity of Hemoblot is 0.15 mg haemoglobin/g faeces and the test is specific for human haemoglobin. In addition, 135 symptomatic patients who had to undergo a colonoscopy were tested using the three tests. Two criteria were considered for the analysis: (1) the blood criterion: any pathology likely to cause colorectal or other bleeding; and (2) the precancerous-cancerous criterion: the pathology being either a colorectal polyp > 0.5 cm or a colorectal cancer. Considering both criteria, the sensitivity of Hemoblot was significantly higher than the sensitivity of Hemoccult: 38% and 23%, respectively, for the blood criterion; and 54% and 29% for the precancerous-cancerous criterion. Sensitivity and specificity did not differ statistically between Hemoblot and HemeSelect but Hemoblot was faster and simpler to perform. It could be widely used in mass screening. [less ▲]

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See detailQuand la chimie s’en mêle
Flandroy, P; Grandfils, Christian ULg

in le Journal du Médecin (1994), 16

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See detailCompte rendu de V. Langholf, Medical Theories in Hippocrates, Berlin-New York, 1990
Marganne, Marie-Hélène ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1994), 63

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See detailFavoriser la reproduction des poissons à Lanaye.
Poncin, Pascal ULg; Keulen, C.

in Pêcheur Belge (Le) (1994), 6

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See detailLe contrôle de l'infection par le virus de la rhinotrachéite infectieuse bovine
Lemaire, Mylène; Pastoret, Paul-Pierre ULg; Thiry, Etienne ULg

in Annales de Médecine Vétérinaire (1994), 138

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See detailIdentification Of Distinct Potyviruses In Mixedly-Infected Sweet-Potato By The Polymerase Chain-Reaction With Degenerate Primers
Colinet, D.; Kummert, J.; Lepoivre, Philippe ULg et al

in Phytopathology (1994), 84(1),

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See detailInvolvement Of The Cyclic Amp-Responsive Element-Binding Protein In Bovine Leukemia-Virus Expression In-Vivo
Adam, E.; Kerkhofs, P.; Mammerickx, M. et al

in Journal of Virology (1994), 68(9),

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See detailStructural and functional features of bovine leukemia virus gp51 head domain. Towards a general model for oncovirus envelope glycoproteins.
Callebaut, Isabelle; Portetelle, Daniel ULg; Burny, Arsène et al

in European Journal of Biochemistry (1994), 222(2), 405-414

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See detailPathogenesis of migraine: the biobehavioural and hypoxia theories reconciled.
Schoenen, Jean ULg

in Acta Neurologica Belgica (1994), 94(2), 79-86

The recent pathophysiological data obtained in migraine patients during and between attacks are reviewed in this article. They suggest that the headache in migraine is due to activation of the trigemino ... [more ▼]

The recent pathophysiological data obtained in migraine patients during and between attacks are reviewed in this article. They suggest that the headache in migraine is due to activation of the trigemino-vascular system. While this can be found in other headache disorders, the process leading ultimately to trigemino-vascular activation appears to characterize migraine. Between attacks, the migrainous brain has two functional abnormalities: a habituation defect in sensory processing, probably related to dysfunctioning transmitter (serotonin, noradrenaline) systems and a reduced mitochondrial energy reserve. Both abnormalities may be genetically determined and concur to favour biochemical shifts leading to the migraine attack as a primary protective mechanism of the brain. Such a model of migraine pathogenesis reconciles the biobehavioural and hypoxia theories and opens new therapeutic perspectives. [less ▲]

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See detailMicrostructural study of a zinc-aluminium-copper alloy after thermal treatment at 100°C and creep
Terziev, L.; Lecomte-Beckers, Jacqueline ULg; Wegria, J.

in Zeitschrift für Metallkunde (1994), 85[9]

The creep behaviour of the ternary Zn—A1—Cu alloy after thermal treatment at ioo oc has been studied. The applied creep stress does flot modify clearly the transition phases (OL, T% ‘11m) appearing during ... [more ▼]

The creep behaviour of the ternary Zn—A1—Cu alloy after thermal treatment at ioo oc has been studied. The applied creep stress does flot modify clearly the transition phases (OL, T% ‘11m) appearing during isothermal ageing. During the creep test, the formation of an important density of defects resuits in the precipitation of T’ and O’ particles. The quantity of these phases depends on the creep conditions. [less ▲]

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See detailVaricelle létale. Etude immunohistochimique et par hybridation in situ
Nikkels, Arjen ULg; Delvenne, Philippe ULg; Sadzot-Delvaux, Catherine ULg et al

in Annales de Dermatologie et de Vénéréologie (1994), 121(2), 113-117

We report a case of lethal varicella developed in an immunocompromised man in his seventies. A study by immunohistochemistry and in situ hybridization was conducted revealing the presence of the ... [more ▼]

We report a case of lethal varicella developed in an immunocompromised man in his seventies. A study by immunohistochemistry and in situ hybridization was conducted revealing the presence of the glycoprotein gpI specific for VZV and its corresponding nucleic acids found in multiple foci of most tissues and organs, except in the brain and paravertebral sympathetic ganglia. [less ▲]

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See detailH3-receptor regulation of vascular gastrin and somatostatin releases by the isolated rat stomach.
Bado, A.; Moizo, L.; Laigneau, J. P. et al

in Yale Journal of Biology and Medicine (The) (1994), 67(3-4), 113-121

We have studied the effects of the H3-receptor agonist (R) alpha-methylhistamine [(R) alpha-MeHA] and the H3-receptor antagonist thioperamide (Thiop) on basal- and carbachol-stimulated vascular gastrin ... [more ▼]

We have studied the effects of the H3-receptor agonist (R) alpha-methylhistamine [(R) alpha-MeHA] and the H3-receptor antagonist thioperamide (Thiop) on basal- and carbachol-stimulated vascular gastrin release (GR) and somatostatin release (SR) by the isolated rat stomach. Carbachol dose-dependently stimulated and inhibited GR and SR, respectively. Maximal stimulation of GR (500 +/- 112 percent of basal; p < .01), and maximal inhibition of SR (-62 +/- 9 percent under basal; p < .01) were obtained with 1 micron carbachol. Neither (R)alpha-MeHA nor Thiop, up to 10 microns, affected GR. However, SR was dose-dependently enhanced by Thiop (25 +/- 8 percent for 10 microns). Carbachol stimulation of GR was strongly inhibited by Thiop (30 +/- 7 percent for 100 nM and 73 +/- 14 percent for 1 microgram), whereas it was potentiated by (R)alpha-MeHA. Carbachol inhibition of SR was reversed by Thiop and (R)alpha-MeHA. However, the reversal effect of (R)alpha-MeHA was prevented by the CCKB/gastrin receptor antagonist PD134308. These results support H3-receptor regulation of basal and cholinergically-stimulated GR and SR. [less ▲]

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See detailValeurs de référence de la ferritine sérique chez l'adulte
Vernet, M.; Revenant, M. C.; Charlier, Corinne ULg et al

in Annales de Biologie Clinique (1994), 52

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See detailL'autisme et la pensée du temps
Gauthier, Jean-Marie ULg

in Recherches du centre international de psychosomatique (1994), 1

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See detailCoupling and carbonylation of iodoaromatics and terminal alkynes or alkynols catalyzed by a dimeric palladium hydroxide
Delaude, Lionel ULg; Masdeu, Anna M.; Alper, Howard

in Synthesis (1994), (11), 1149-1151

The palladium(II) complex [(Ph(3)P)Pd(Ph)mu-OH)](2) is an effective catalyst for the coupling and carbonylation of alkynes and iodoarenes to give acetylenic ketones in 63-94% yields. Acetylenic hydroxy ... [more ▼]

The palladium(II) complex [(Ph(3)P)Pd(Ph)mu-OH)](2) is an effective catalyst for the coupling and carbonylation of alkynes and iodoarenes to give acetylenic ketones in 63-94% yields. Acetylenic hydroxy ketones were formed using secondary or tertiary alkynols as reactants. [less ▲]

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See detailNatural-Convection Above Line Heat-Sources In Greenhouse Canopies
Aubinet, Marc ULg; Deltour, Jules

in International Journal of Heat and Mass Transfer (1994), 37(12),

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See detailIncidence des aménagements hydrauliques sur le contrôle du développement de la bilharziose (shistosomiase)
Pliez, A.; Moens, R.; Debouche, Charles ULg

in Annales de Gembloux (1994), (100), 53-65

Le développement des irrigations dans les zones tropicales et subtropicales du monde, pour augmenter les productions de nourriture, a provoqué la prolifération de maladies liées à l'eau comme la ... [more ▼]

Le développement des irrigations dans les zones tropicales et subtropicales du monde, pour augmenter les productions de nourriture, a provoqué la prolifération de maladies liées à l'eau comme la bilharziose (également appelée shistosomiase), la dengue, la filariose et l'onchocercose. [less ▲]

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See detailEtude du reservoir genetique de la legumineuse alimentaire Phaseolus lunatus L. par l'analyse electrophoretique d'isozymes.
Maquet, A.; Wathelet, Bernard ULg; Baudoin, Jean-Pierre ULg

in Bulletin des Recherches Agronomiques de Gembloux (1994), 29(3),

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See detailLes défis des familles recomposées
Guillaume, Jean-François ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 6(novembre-décembre), 30-36

Dans un contexte de croissance des recompositions conjugales après divorce, la prise en charge des tâches parentales constitue un défi inédit, où il s'agit pour les uns de retrouver des repères bien ... [more ▼]

Dans un contexte de croissance des recompositions conjugales après divorce, la prise en charge des tâches parentales constitue un défi inédit, où il s'agit pour les uns de retrouver des repères bien connus, et pour les autres, d'imaginer un nouvel ordre éducatif. Une nouvelle histoire doit alors être créée, et dans ce "bricolage", chacun ne dispose pas des mêmes ressources pour trouver sa place. [less ▲]

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See detailA Dynamic Stiffness-Transfer Matrix Method for Forced Response Analysis of One-Dimensional Structures
Chen, S. L.; Golinval, Jean-Claude ULg; Géradin, Michel ULg

in Journal of Modal Analysis (1994), (Avril),

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See detailCircadian rhythms and the induction of flowering in the long-day grass Lolium temulentum L.
Périlleux, Claire ULg; Bernier, Georges ULg; Kinet, Jean Marie

in Plant, Cell & Environment (1994), 17(6), 755-761

Plants of Lolium temulentum L. strain Ceres were grown in 8-h short day (SD) for 45 d before being exposed either to a single long day (LD) or to a single 8-h SD given during an extended dark period. For ... [more ▼]

Plants of Lolium temulentum L. strain Ceres were grown in 8-h short day (SD) for 45 d before being exposed either to a single long day (LD) or to a single 8-h SD given during an extended dark period. For LD induction, the critical photoperiod was between 12 and 14 h, and more than 16 h were needed for a maximal flowering response. During exposure to a single 24-h LD, the translocation of the floral stimulus began between the fourteenth and the sixteenth hours after the start of the light period, and was completed by the twenty-fourth hour. Full flowering was also induced by one 8-h SD beginning 4 or 28 h after the start of a 40-h dark period, i.e. by shifting 12 h forward or beyond the usual SD. The effectiveness of a so-called 'displaced short day' (DSD) was not affected by light quality and light intensity. With a mixture of incandescent and fluorescent lights at a total photosynthetic photon flux density of 400 µmol m-2 s-1, a 4-h light exposure beginning 4 h after the start of a 40-h dark period was sufficient to induce 100 flowering. The flower-inducing effect of a single 8-h DSD was also assessed during a 64-h dark period. Results revealed two maxima at a 20-h interval. This fluctuation in light sensitivity suggests that a circadian rhythm is involved in the control of flowering of L. temulentum. [less ▲]

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See detailThe Dissociative Electroionization of C2H2, C2D2 and C2HD. Investigation of the [C2H(D)]+ and [H(D)]+ Dissociation Channels. The (D)H-C2H(D) binding energy.
Davister, M.; Locht, Robert ULg

in Chemical Physics (1994), 189

The dissociative electroionization of C2H2 in the H+ and C2H+ dissociation channels has been extensively investigated in C2H2 and C2D2. The kinetic energy distributions and ionization efficiency curves of ... [more ▼]

The dissociative electroionization of C2H2 in the H+ and C2H+ dissociation channels has been extensively investigated in C2H2 and C2D2. The kinetic energy distributions and ionization efficiency curves of both species were examined in detail. The H(D)+ ion shows its lowest onset energy at 18.93+/-0.2 eV whereas the C2H+ is produced at 17.30+/-0.11 eV. For the H+-producing channel the kinetic energy (KE) versus the appearance energy (AE) diagram is obtained, extensively discussed and the bond dissociation energy D(H-C2H)= 5.33+/-0.23 eV is estimated. This value is compared and discussed with respect to the values found in the literature. Predissociation and dissociative autoionization are the dominant H+-producing mechanisms. At high electron energies doubly ionized states of C2H2 are involved. For C2H+, beside the threshold at 17.30+/0.11 eV a new onset at 18.27+/0.10 eV is observed. The ionization efficiency of the doubly ionized molecular ion is observed for the first time in C2HD isotopic species. [less ▲]

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See detailMBO en Aandeelhouder
Corhay, Albert ULg; Herst, Arthur; Tourani Rad, Alireza

in Bedrifskunde (1994), 4

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See detailLa rentabilité de l'activité hélicicole
Lebailly, Philippe ULg

in Agricontact (1994), (259 (mars)), 11-16

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See detailModulation of the acetylcholine- and substance P-induced pulmonary edema by calcitonin gene-related peptide in the rabbit.
Delaunois, Annie ULg; Gustin, Pascal ULg; Ansay, Michel ULg

in Journal of Pharmacology and Experimental Therapeutics (The) (1994), 270(1), 30-6

The effects of calcitonin gene-related peptide (CGRP) (6 x 10(-8) M) on hemodynamics and on pulmonary microvascular permeability were investigated in isolated, perfused rabbit lungs by measuring the ... [more ▼]

The effects of calcitonin gene-related peptide (CGRP) (6 x 10(-8) M) on hemodynamics and on pulmonary microvascular permeability were investigated in isolated, perfused rabbit lungs by measuring the arterial, capillary and venous pressures and the capillary filtration coefficient (Kf,c). CGRP was administered alone or in combination with capsaicin (10(-4) M), acetylcholine (ACh) (10(-11) M to 10(-7) M), substance P (SP) (10(-10) M to 10(-6) M) and serotonin (10(-4) M). The influence of a specific antagonist of CGRP receptors, CGRP8-37 (10(-8) M), on the pulmonary edema induced by these mediators was also considered. CGRP had no direct effect on the vascular pressures or on Kf,c. Capsaicin and serotonin induced an increase in Kf,c of 271 +/- 49% and 676 +/- 147% of base line, respectively. ACh and SP also increased the microvascular permeability, in proportion to the concentration. The effects of capsaicin, ACh and SP have been related to the activation of neurokinin NK1 receptors. Co-administration of CGRP with capsaicin and ACh enhanced the increase in Kf,c induced by these two drugs. By contrast, when co-injected with SP, CGRP inhibited the Kf,c increase induced by 10(-8) M and 10(-7) M of SP (P < .05) and significantly decreased the arterial and capillary pressures. CGRP also partly prevented the pulmonary edema induced by serotonin (P < .05). Pretreatment with CGRP8-37 partly prevented the effects of capsaicin and ACh on Kf,c but bestowed no protection against SP-induced pulmonary edema. These data suggest that CGRP is co-released with SP from the C-fibers upon the action of capsaicin and ACh in the rabbit lung. Because CGRP potentiated the pulmonary edema induced in capsaicin and ACh, but decreased the effects of SP, we hypothesize that CGRP exerts a positive retro-control on the release of neuropeptides by these fibers but can attenuate their effects on the target cells. [less ▲]

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See detailPure red cell aplasia following peripheral stem cell transplantation: complete response to a short course of high-dose recombinant human erythropoietin.
Martelli, M.; Ponchio, L.; Beguin, Yves ULg et al

in Haematologica (1994), 79(5), 456-9

We studied a patient who developed pure red cell aplasia (PRCA) following peripheral stem cell transplantation for non-Hodgkin lymphoma. Serum erythropoietin was appropriate for the degree of anemia ... [more ▼]

We studied a patient who developed pure red cell aplasia (PRCA) following peripheral stem cell transplantation for non-Hodgkin lymphoma. Serum erythropoietin was appropriate for the degree of anemia. Corticosteroid treatment was ineffective. Four months after transplantation rHuEpo was administered subcutaneously at a dose of 150 U/Kg per day, five days a week for 8 weeks. Treatment induced an erythropoietic response and corrected anemia. Response was maintained following discontinuation of rHuEpo. This study and previous reports indicate that high doses of rHuEpo given over a short time can resolve PRCA following autologous or allogeneic stem cell transplantation. [less ▲]

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See detailLATTICE-DYNAMICS AND DIELECTRIC-PROPERTIES OF INCIPIENT FERROELECTRIC TIO2 RUTILE
LEE, C.; Ghosez, Philippe ULg; GONZE, X.

in Physical Review. B : Condensed Matter (1994), 50(18), 13379-13387

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See detailImportance des insectes ravageurs des cereales stockees en Belgique.
Letellier, C.; Haubruge, Eric ULg; Gaspar, Charles ULg

in Parasitica (1994), 50(1-2),

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See detailVibration amplitudes caused by parametric excitation of cable stayed structures
Lilien, Jean-Louis ULg; Pinto da Costa, Antonio

in Journal of Sound & Vibration (1994), 174(N°1), 69-90

This paper deals with one kind of cable vibrations : the ones caused by parametric excitation.

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See detailParadoxe sur le philosophe (kant entre Bourdieu et Derrida)
Steinmetz, Rudy ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (1994)

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See detailIndia Song ou le temps tragique
Badir, Sémir ULg

in Cinémas (1994), 5(1-2), 123-133

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See detailL'inventaire forestier régional wallon: brève présentation méthodologique.
Lecomte, H.; Rondeux, Jacques ULg

in Silva Belgica (1994), 101(6), 9-16

Au début des années 1980, à l’initiative de la Faculté des Sciences agronomiques de Gembloux et grâce à un financement de la Région Wallonne, un inventaire a été réalisé sur l’ensemble de la Wallonie ... [more ▼]

Au début des années 1980, à l’initiative de la Faculté des Sciences agronomiques de Gembloux et grâce à un financement de la Région Wallonne, un inventaire a été réalisé sur l’ensemble de la Wallonie [RONDEUX et al., 1984]. Cet inventaire s’appuyant sur un échantillonnage systématique simple était destiné à fournir un état des lieux de la forêt wallonne de l’époque ; il a notamment permis de confirmer ou de mettre en évidence plusieurs éléments essentiels pour l’avenir du patrimoine forestier wallon [RONDEUX et al., 1986] : - le vieillissement de la hêtraie ardennaise ; - l’importante disponibilité en bois d’épicéa ; - les écarts entre les surfaces forestières observées et celles du recensement officiel. Depuis la fin de cet inventaire en 1984, aucune mise à jour n’a été programmée et en conséquence, ses résultats ont perdu leur fiabilité notamment en raison des accidents météorologiques de la dernière décennie. En 1988, l’Exécutif de la Région Wallonne, conscient de l’importance de la forêt en tant que première ressource naturelle renouvelable de la Wallonie, a sollicité la Faculté des Sciences agronomiques de Gembloux en vue de finaliser une recherche destinée à concevoir une méthodologie d’inventaire forestier permanent. Les conclusions de cette étude ont été déposées fin 1993 [LECOMTE, 1994], ce qui a permis de lancer dès février 1994 la phase opérationnelle du premier inventaire forestier permanent pour la Wallonie. Dans les lignes qui suivent, nous aborderons successivement les objectifs de l’inventaire (paragraphe 2) ainsi que les principes généraux qui le régissent (paragraphe 3). Le cheminement de l’information sera décrit depuis la récolte des données (paragraphe 4) jusqu’à la publication des résultats (paragraphe 7) en passant par le traitement et l’exploitation des données (paragraphes 5 et 6). En guise de conclusions, nous émettrons quelques réflexions issues de notre propre expérience (paragraphe 8). [less ▲]

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See detailComment évaluer la sensibilité à l'insuline en pratique?
Scheen, A. J.; Paquot, Nicolas ULg; Letiexhe, M. R. et al

in Diabète & Métabolisme (1994), 20(6, Nov-Dec), 556-61

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See detailMeasurement of insulin sensitivity by the minimal model method using a simplified intravenous glucose tolerance test: validity and reproducibility.
Duysinx, Bernard ULg; Scheen, André ULg; Gerard, Pascale ULg et al

in Diabète & Métabolisme (1994), 20(4), 425-32

This study aimed at testing whether 12 rather than 26 plasma glucose and insulin determinations can be used to calculate the indices of insulin sensitivity and of glucose effectiveness using Bergman's ... [more ▼]

This study aimed at testing whether 12 rather than 26 plasma glucose and insulin determinations can be used to calculate the indices of insulin sensitivity and of glucose effectiveness using Bergman's minimal model during a simple intravenous glucose tolerance test performed without tolbutamide injection. Two intravenous glucose tolerance tests (separated by 1 week) were performed in 7 lean normal subjects and a single test was performed in 9 severely obese non-diabetic subjects. Intra-subject reproducibility of insulin sensitivity was not significantly different when 26 or 12 time-points were analyzed (CV = 16.8 +/- 3.4 versus 18.9 +/- 3.8% respectively). Compared with the insulin sensitivity of the lean subjects, that of obese subjects was significantly (P < 0.001) and similarly reduced when using 12 (2.14 +/- 0.34 versus 7.97 +/- 1.29 10(-4)min-1/mU.1-1) rather than 26 determinations (2.13 +/- 0.42 versus 6.95 +/- 1.12 10(-4) min-1/mU.1-1) respectively. Glucose effectiveness was less reproducible than insulin sensitivity and was slightly diminished by the reduction of blood samples (relative error: -9.7 +/- 4.4%; P < 0.05). Finally, glucose effectiveness tended to be slightly lower in the morbidly obese subjects than in the lean controls with both modes of calculation. In conclusion, in non-diabetic subjects, the insulin sensitivity index can be accurately measured during a simple intravenous glucose tolerance test, without tolbutamide injection and with only 12 blood samples. The possibility of performing a simplified test should contribute to increase the use of the minimal model method for estimating insulin sensitivity in clinical practice. [less ▲]

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See detailCLOE, A NEW RATE-TYPE CONSTITUTIVE MODEL FOR GEOMATERIALS THEORETICAL BASIS AND IMPLEMENTATION
CHAMBON, René; DESRUES, Jacques; HAMMAD, Wallid et al

in International Journal for Numerical and Analytical Methods in Geomechanics (1994), 18(4), 253-278

The paper describes the basic ideas and the main features of a new class of constitutive laws, in the framework of incrementally non-linear constitutive equations. CLoE is a generic name for that new ... [more ▼]

The paper describes the basic ideas and the main features of a new class of constitutive laws, in the framework of incrementally non-linear constitutive equations. CLoE is a generic name for that new class of laws, with reference to consistency at the limit surface, and explicit localization analysis. A top-down analysis of the model is presented, and illustrated by examples. [less ▲]

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See detailSelective Antiprotozoal Activity of Some Strychnos Alkaloids
Wright, Colin; Allen, David; Cai, Ya et al

in Phytotherapy Research (1994), 8

The in vitro activities of 28 Strychnos alkaloids have been determined against three species of protozoa and the most active compounds were then assessed for in vitro cytotoxic activity against KB cells ... [more ▼]

The in vitro activities of 28 Strychnos alkaloids have been determined against three species of protozoa and the most active compounds were then assessed for in vitro cytotoxic activity against KB cells. 3',4'-dihydrousambarensine was the most active against Plasmodium falciparum and was relatively nontoxic to KB cells (cytotoxic/antiplasmodial ratio, 1474). Usambarensine displayed the most selectivity against Entamoeba histolytica while "',4'-dihydrousambarensine was the most selective compound against Giardia intestinalis although the cytotoxic/antiprotozoal ratios (20.4 and 6.6 respectively) were less favourable than the above.The four strychnobiline-type alkaloids were found devoid of activity against E. histolytica and G. intestinalis but to have weak antiplasmodial properties (7-13 times less active than chloroquine). None of the compounds containing only one indole ring system displayed antiprotozoal properties. [less ▲]

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See detailCLAY SUPPLIES IN THE CENTRAL INDIAN BASIN SINCE THE LATE MIOCENE - CLIMATIC OR TECTONIC CONTROL
Fagel, Nathalie ULg; DEBRABANT, P.; André, Luc

in Marine Geology (1994), 122(1-2), 151-172

Mineralogical (X-ray diffraction, differential thermal analysis), geochemical [microprobe, inductively coupled plasma (ICP)-atomic emission spectrometry, ICP-mass spectrometry] and Sr-Nd isotopic analyses ... [more ▼]

Mineralogical (X-ray diffraction, differential thermal analysis), geochemical [microprobe, inductively coupled plasma (ICP)-atomic emission spectrometry, ICP-mass spectrometry] and Sr-Nd isotopic analyses have been carried out on the clay size fraction of Late Miocene to Pleistocene sediments from the Central Indian Basin. The samples were taken from five giant cores recovered between 1-degree and 10-degrees-S on a transect along 80-degree-E. The clay assemblages are homogeneous and characterized by an alteration of illite- and smectite-rich levels. Most of the clays are detrital and were derived from a unique source: the weathering of the Indo-Gangetic Plain supplied most of the eroded material. Temporal clay mineralogical fluctuations in the depositional basin reflect environmental changes in the provenance. On the basis of spectral analyses of a mineralogical parameter (peak height ratios), the fluctuating smectite-illite clay sedimentation is controlled by periodic Late Miocene climatic changes. During the Late Pliocene, an irregular, probably tectonic, control appeared. [less ▲]

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See detailApplied methodology to delineate protection zones around pumping wells
Dassargues, Alain ULg

in Journal of Environmental Hydrology (1994), 2(2), 3-10

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See detailCalcitropic effect of recombinant prolactins in Oreochromis mossambicus
Flik, G.; Rentier-Delrue, Françoise ULg; Wendelaar-Bonga, S. E.

in The American Physiological Society (1994)

Homologous recombinant tilapia prolactins 1 and 2 were tested for calcitropic activity in tilapia Oreochromis mossambicus. Injection of both PRLs induced hypercalcemia that resulted for an enhanced ... [more ▼]

Homologous recombinant tilapia prolactins 1 and 2 were tested for calcitropic activity in tilapia Oreochromis mossambicus. Injection of both PRLs induced hypercalcemia that resulted for an enhanced calcium influx via the gills and a decreased calcium efflux. Both PRLs increased the density of the Ca2+-transporting Ca2+-adenosinetriphosphatase in a plasma membrane preparation of the branchial epithelium. Dose-response studies demonstrated that the PRL-1 was roughly twofold more potent than PRL2 in inducing hypercalcemia, in enhacing basal levels of cortisol and in stimulating opercular ionocyte density. But both PRL were equipotent in stimulating the dermal mucocyte frequency. [less ▲]

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See detail3D turbulence field on the north-western european continental-shelf
Martin, Géraldine ULg; Delhez, Eric ULg

in Tellus : Series A (1994), 46(2), 98-112

The 3-dimensional, non-linear, baroclinic, GHER mathematical model for the study of mesoscale motions (time scale of several hours to several days: tides, storm surges, ...) is described. Particular ... [more ▼]

The 3-dimensional, non-linear, baroclinic, GHER mathematical model for the study of mesoscale motions (time scale of several hours to several days: tides, storm surges, ...) is described. Particular attention is paid to the turbulent closure based on an evolution equation for the turbulent kinetic energy and a parametric expression of the mixing length (k-model). Appropriate boundary conditions and numerical techniques (mode-splitting, implicity, sigma-coordinate system, advection scheme) are described. The model is applied to the simulation of the M2 tide on the North-Western European Continental Shelf not only without wind but also in typical winter and summer conditions. Large spatial variations of the turbulent kinetic energy appear as a result of the variations of depth and tidal activity around the shelf. These variations are clearly related to the different turbulence regimes observed in summer, with frontal structures separating well-mixed waters from stratified ones. The structure and evolution of the vertical profiles of turbulence variables are described and explained in barotropic and baroclinic conditions, under different wind forcings. The evolution of these profiles at the M2 tide frequency largely depends on the eccentricity of the tidal ellipse. [less ▲]

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See detailAspects épidémiologiques du suicide
Gosset, Christiane ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (1994), 2

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See detailPreservation of Oocyte and Granulosa Cell Morphology in Bovine Preantral Follicles Cultured in Vitro
Figueiredo, J. R.; Hulshof, S. C.; Van den Hurk, R. et al

in Theriogenology (1994), 41(6), 1333-46

Described in the present paper is a culture system that preserves oocyte and granulosa cell morphology in bovine preantral follicles during 5 d in vitro. The effects of additional hypoxanthine and energy ... [more ▼]

Described in the present paper is a culture system that preserves oocyte and granulosa cell morphology in bovine preantral follicles during 5 d in vitro. The effects of additional hypoxanthine and energy substrata (i.e., pyruvate and glutamine) on the morphology of cultured preantral follicles were investigated. It was shown that addition of a mixture of pyruvate, glutamine and hypoxantine to the culture medium increased the percentage of follicles with an intact oocyte from 29.4 to 78.6%. Morphological criteria are described to discriminate between normal and degenerated preantral follicles during culture by inverted microscopy. In addition, the importance of histological evaluation to judge the quality of oocyte and granulosa cells is demonstrated. [less ▲]

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See detailAnalysis methodology, experimental investigation and computer optimization of a passive solar commercial building in the Belgian climate
Andre, Philippe ULg; Nicolas, Jacques ULg; Rivez, Jean-François et al

in Solar Energy (1994), 52(1), 9-25

The Fondation Universitaire Luxembourgeoise (FUL) building (completed in 1986) has been selected as a Belgian candidate for participation in the IEA (International Energy Agency) Task XI project devoted ... [more ▼]

The Fondation Universitaire Luxembourgeoise (FUL) building (completed in 1986) has been selected as a Belgian candidate for participation in the IEA (International Energy Agency) Task XI project devoted to passive solar commercial buildings. Therefore, an evaluation methodology has been set up and a monitoring plan has been defined and performed. Together with this experimental investigation, intensive computer simulation work has defined an optimized design of the building. The main results show that the recorded performance can be improved to an extent of 15% energy savings, which yields a correct performance for a passive solar building in the temperate maritime Belgian climate. [less ▲]

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See detailStereoelectronic properties of five anti-HSV-1 2′-deoxynucleosides analogues with heterocyclic substituents in the 5-position: A comparison with BVDU
Olivier, Anne; Creuven, Isabelle; Evrard, Christine ULg et al

in Antiviral Research (1994), 24

Structural and electronic characteristics of 5-(5-chlorothien-2-yl)-2′-deoxyuridine (I), 5-(furan-2-yl)-2′-deoxyuridine (II), 5-(5-bromofuran-2-yl)-2′-deoxyuridine (III), 5-(3-bromoisoxazol-5-yl)-2′ ... [more ▼]

Structural and electronic characteristics of 5-(5-chlorothien-2-yl)-2′-deoxyuridine (I), 5-(furan-2-yl)-2′-deoxyuridine (II), 5-(5-bromofuran-2-yl)-2′-deoxyuridine (III), 5-(3-bromoisoxazol-5-yl)-2′-deoxyuridine (V) and 5-(isoxazol-5-yl)-2′-deoxyuridine (IV) have been determined and compared to the BVDU (VI) characteristics in order to explain their respective affinity for the herpes simplex virus type 1 thymidine kinase (TK). Molecular structure of 5-(5-chlorothien-2-yl)-2′-deoxyuridine has been obtained using single crystal X-ray crystallography. Electrostatic potential maps, energy and topology of frontier orbitals were computed at the ab initio MO STO-3G and STO-3G* level. These studies reveal that the electrostatic potential energy maps are clearly dependent on the affinity of the compound for the enzyme. [less ▲]

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See detailYeast excision repair RAD2 encodes a single-stranded DNA endonuclease
Habraken, Yvette ULg; Sung, Partick; Prakash, Louise et al

in Nature (1993), 366

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See detailMagnetic Eden model
Ausloos, Marcel ULg; Vandewalle, Nicolas ULg; Cloots, Rudi ULg

in Europhysics Letters [=EPL] (1993), 24(8), 629-634

We introduce the <<Magnetic Eden Model(s)>>. It consists in the usual Eden growth model(s), but allowing for the elements of the growth to have an extra degree of freedom (a <<spin>>). The growth is ... [more ▼]

We introduce the <<Magnetic Eden Model(s)>>. It consists in the usual Eden growth model(s), but allowing for the elements of the growth to have an extra degree of freedom (a <<spin>>). The growth is controlled by a condition depending on the <<magnetic state>> of the perimeter (through some <<spin coupling>>) and an external parameter, the <<magnetic field>>. Even though these words seem to refer to some <<energetic condition>> the growth model is of purely kinetic origin. This is demonstrated by exactly solving the 1-dimensional growth model for a semi-open chain, and, e.g. finding the correlation functions. In two-dimensions, simulations of clusters lead us to show that the perimeter growth exponent is coupling dependent. We show the morphologies of growth clusters on a <<phase diagram>> and indicate the <<physical origin>> and transition(s) between compact and lacunar clusters. [less ▲]

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See detailFully Automated Determination of Sulfamethazine in Ovine Plasma Using Solid-Phase Extraction on Disposable Cartridges and Liquid Chromatography
Hubert, Philippe ULg; Chiap, Patrice ULg; Evrard, Brigitte ULg et al

in Journal of Chromatography. A (1993), 622(1), 53-60

An automatic sample preparation procedure followed by on-line injection of the sample extract into a HPLC system has been developed for the quantitative analysis of sulfamethazine and its N4-acetyl ... [more ▼]

An automatic sample preparation procedure followed by on-line injection of the sample extract into a HPLC system has been developed for the quantitative analysis of sulfamethazine and its N4-acetyl metabolite in ovine plasma. The sample clean-up was performed by solid-phase extraction (SPE) on C18 disposable extraction cartridges (DECs). All the sample handling operations were effected by a robotic auto-sampler. The DEC was first conditioned with methanol and phosphate buffer pH 7.4. After loading 1.0 ml of plasma sample onto the DEC, the latter was washed with the same buffer. The elution step was performed with methanol (0.25 ml) and the eluate was then diluted by adding 0.75 ml volume of phosphate buffer pH 6.4. A 20-microliters volume of the resultant solution was injected onto an octadecyl silica column preceded by a short guard column. The HPLC mobile phase was methanol-phosphate buffer pH 6.4 (25:75, v/v). Sulfamethazine and N4-acetylsulfamethazine were determined photometrically at 262 nm. Under these conditions, linear calibration curves ranging from 2 to 250 micrograms ml-1 have been obtained for both compounds. Drug recoveries were higher than 90% and typical relative standard deviation values were 0.7% (within-day) and 2.0% (between-day) at a plasma concentration of 50 micrograms ml-1. [less ▲]

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See detailAnionic polymerization of acrylic monomers. 11 NMR investigation of the mixed complexation of methyl α-lithioisobutyrate and lithium chloride
Wang, Jin-Shan; Warin, R.; Jérôme, Robert ULg et al

in Macromolecules (1993), 26

Solutions of methyl α-lithioisobutyrate (MIBLi) in THF added with various amounts of lithium chloride (LiCl) have been analyzed by Li-7 NMR spectroscopy in a wide range of temperatures. Although below ca ... [more ▼]

Solutions of methyl α-lithioisobutyrate (MIBLi) in THF added with various amounts of lithium chloride (LiCl) have been analyzed by Li-7 NMR spectroscopy in a wide range of temperatures. Although below ca. 205 K tetramers of MIBLi have been reported to be in equilibrium with dimers, 1/1 and 2/1 LiCl/MIBLi mixed complexes instantaneously form upon the addition of 1 and 2 mol equiv of LiCl, respectively. Further addition of LiCl more likely promotes the formation of a less stable 3/1 complex. Both 1/1 and 2/1 adducts are stable between -80-degrees-C and at least +12-degrees-C. From C-13 NMR spectroscopy, it appears that the addition of an equimolar amount of LiCl to the MIBLi solution in THF is at the origin of a ca. 7.0 ppm upfield shift of the metalated α-carbon compared to the tetrameric MIBLi species and a ca. 1.0 ppm downfield shift with respect to the dimeric MIBLi. However, the charge distribution over the carbanion does not change anymore when the amount of LiCl exceeds 1 mol equiv. In contrast to nonligated MEBLi, the OR group has a considerable rotational freedom in LiCl-modified MIBLi. A comparison of the structure and dynamics of the LiCl-modified MIBLi species in THF at 197 K with the characteristic features of the anionic polymerization of MMA under the same conditions suggests that the formation of one type of LiCl-complexed species has a decisive effect on the control of the living polymerization of MMA. This conclusion is in agreement with a kinetic study carried out by Muller for the same system. [less ▲]

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See detailSelective gravitational microlensing and line profile variations in the BAL quasar H 1413+117
Hutsemekers, Damien ULg

in Astronomy and Astrophysics (1993), 280

In order to interpret the spectral differences observed between the four images of the gravitationally lensed broad absorption line (BAL) quasar H 1413+117, we have investigated the effect on the line ... [more ▼]

In order to interpret the spectral differences observed between the four images of the gravitationally lensed broad absorption line (BAL) quasar H 1413+117, we have investigated the effect on the line profiles of the selective magnification of individual BAL clouds by gravitational microlenses. Since microlenses magnify both the selected cloud and the whole BAL region, this effect is only differential, and general constraints on its capability to produce spectral variations have been derived. Considering simple but realistic models for the microlenses, we find that the selective magnification of a relatively large optically thick BAL cloud can be at the origin of the spectral differences reported between the components of H 1413+117. However, a very precise configuration is needed: the magnified cloud must be at the border of the BAL region which must itself partially lie in a region of strong de-magnification. The fine tuning of the parameters mecessary to reproduce the observations either seriously questions this kind of interpretation or puts strong constraints on the lensing models. Another interpretation of the observed line profile differences in terms of effects due to microlensing is also briefly discussed. [less ▲]

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See detailIpriflavone: Pharmacological Properties and Usefulness in Postmenopausal Osteoporosis
Reginster, Jean-Yves ULg

in Bone and Mineral (1993), 23(3), 223-32

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and ... [more ▼]

Ipriflavone (IP) is an isoflavone derivative available in several countries for investigational and/or therapeutic use. Inhibition of bone resorption was demonstrated in several models, both in vitro and in vivo for IP and its metabolites. Their mechanisms of action on bone are not yet fully elucidated but some of them are widely accepted. IP does not possess, per se, any estrogenic activity. It appears that IP-related inhibition of bone resorption might be mediated by an indirect effect on osteoclast and related to an inhibition of recruitment and/or differentiation of pre-osteoclast, maybe through a modulation of osteoblast response to PTH. Clinical studies in Paget's disease of bone or primary hyperparathyroidism have confirmed preferential inhibition of bone resorption suggesting a clinical interest in postmenopausal osteoporosis. Preliminary (1 year) results of double blind placebo controlled studies designed in postmenopausal and senile osteoporosis confirm a reduction in bone turnover rate in patients treated with 600 mg/day of IP, resulting in a significant bone-sparing effect both at lumbar and radial levels. All clinical and pharmacological trials confirm a very good tolerance of IP with a frequency of adverse reactions equal to that observed during administration of a placebo. Providing ongoing studies will confirm the actual promising preliminary results, IP seems a very interesting new non hormonal approach for prevention and treatment of postmenopausal and senile osteoporosis. [less ▲]

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See detailField Efficacy of Injectable Moxidectin in Cattle Naturally Infested with Chorioptes Bovis and Sarcoptes Scabiei
Losson, Bertrand ULg; Lonneux, J. F.

in Veterinary Parasitology (1993), 51(1-2), 113-21

Field efficacy of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bovis and Sarcoptes scabiei. Eight animals were allocated to two groups of four ... [more ▼]

Field efficacy of moxidectin, a macrocyclic lactone endectocide, was evaluated in cattle naturally infested with Chorioptes bovis and Sarcoptes scabiei. Eight animals were allocated to two groups of four animals each, based on parasitological and clinical status. Animals of the treated group received one subcutaneous injection of injectable moxidectin at 0.2 mg kg-1 body weight on Day 0. Individuals of the control group received emergency treatment of a single injection of moxidectin at 0.2 mg kg-1 body weight on Day 28. Efficacy was assessed by (a) taking skin samples from each animal on Days 0, 7, 14, 21, 28, 42 and 56 and observing the numbers of viable mite stages and species and (b) clinical examination of animals on Days 7, 14, 21, 28, 42 and 56 with the percentage of affected body surface calculated for each animal on Days 0, 28 and 56. On the basis of the geometric means from treated and control animals, the percentage reductions in the total numbers of living C. bovis mites on Days 7, 14, 21 and 28 were 69, 87, more than 99 and 98, respectively. However, at the end of the trial, only two animals were negative for C. bovis. The percentage reductions in the total numbers of S. scabiei on Days 7, 14, 21 and 28 were 93, 100, 100 and 100, respectively. Clinical indices of the treated animals showed a sharp decrease in the affected body surface area from a mean of 43.6% on Day 0 to 0.9% and 0% on Days 28 and 56, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailLe come back de Nyles Jones a.k.a. GUITAR GABRIEL
Sacré, Robert ULg

in Soul Bag (1993), (129),

Vie et oeuvre de Robert Lewis 'Nyles' JONES ou Guitar Gabriel

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See detailSome Principles and Applications of Adaptive Mathematical Morphology for Range Imagery
Verly, Jacques ULg; Delanoy, Richard L.

in Optical Engineering : The Journal of the Society of Photo-Optical Instrumentation Engineers (1993), 32(12), 3295-3306

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See detailComplement activation during cardiopulmonary bypass in infants and children: Relation to postoperative multiple system organ failure
Seghaye, Marie-Christine ULg; Duchateau, J.; Grabitz, R. G. et al

in Journal of Thoracic and Cardiovascular Surgery (1993), 106(6), 978-987

Twenty-nine children 3 months to 17 years of age undergoing operations for congenital heart disease were included in this prospective study. Complement activation, activation of the plasma contact system ... [more ▼]

Twenty-nine children 3 months to 17 years of age undergoing operations for congenital heart disease were included in this prospective study. Complement activation, activation of the plasma contact system, leukocytes, leukocyte elastase release, and C-reactive protein were studied during and after cardiopulmonary bypass for the first postoperative week and related to multiple system organ failure occurring in eight (27.5 %) of the 29 children. During cardiopulmonary bypass complement activation via the alternative pathway as indicated by significant conversion of C3 (expressed by C3d/C3) and abnormally high C5a values at the end of cardiopulmonary bypass without consumption of C4 was shown in all children. At the end of cardiopulmonary bypass, C3 conversion was significantly higher in the eight patients with multiple system organ failure than in the others (p < 0.05), whereas no difference in C5a level was shown. All children had a significant increase in leukocyte count directly after protamine administration (p < 0.0001) and elastase release during cardiopulmonary bypass that was significantly higher in patients with multiple system organ failure than in those without (p < 0.05). Consumption of prekallikrein as an indicator of activation of the Hageman system was not detectable during cardiopulmonary bypass in any child. After cardiopulmonary bypass, in patients without multiple system organ failure, C3d/C3 decreased and reached preoperative values within the first postoperative week, whereas, in patients with multiple system organ failure, C3d/C3 increased further, reaching a maximal value on the third postoperative day. In comparison with patients without multiple system organ failure, patients with multiple system organ failure showed a severe decrease of C4 (with minimal values on the third postoperative day), suggesting consumption by activation of the classic pathway of the complement system or a hepatic synthesis deficiency. Prekallikrein values were also significantly lower in patients with multiple system organ failure than in the others, with a maximal difference on the third postoperative day (p < 0.005). C-reactive protein was significantly lower in patients with multiple system organ failure than in the others for the first 2 postoperative days (p < 0.05), probably because of severe hepatic failure in patients with multiple system organ failure. This study demonstrates that, in children, cardiopulmonary bypass induces complement activation principally via the alternative pathway. It suggests a relationship between complement activation and multiple system organ failure observed in the postoperative period. Furthermore, it points out the role of multiple system organ failure itself on the C3 conversion and on the synthesis of the markers of the inflammatory response in children after heart operations. [less ▲]

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See detailOppervlakte-biopsie
Nikkels, Arjen ULg; Pierard-Franchimont, Claudine ULg; Pierard, Gérald ULg

in Nederlands Tijdschrift voor Dermatologie en Venereologie (1993), 3

Superficial skin surface stripping (SSSS) enables the study of the outermost cell layers of the stratum corneum. In this article we review the diagnostic value and the research possibilities offered by ... [more ▼]

Superficial skin surface stripping (SSSS) enables the study of the outermost cell layers of the stratum corneum. In this article we review the diagnostic value and the research possibilities offered by SSSS. This technique is non invasive and provides information useful in the differential diagnosis of erythematosquamous and eczematous lesions and pigmented neoplasms. For research purposes SSSS can also be used as substratum for scanning electron microscopic assessments and biochemical analysis. [less ▲]

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See detailClonage par greffe de blastomère: naissance d'un premier veau
Ectors, Fabien ULg; Delval, Alain; Touati, Kamal ULg et al

in Annales de Médecine Vétérinaire (1993), 137(8), 573-574

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See detailEtre ou non branché aux médias
Leclercq, Dieudonné ULg

in Emergence. Revue proposée par l'ICC en collaboration avec MEDIA ANIMATION et le CFA (1993), 21

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See detailMediterranean small mammals and insular syndrome: biometrical study of the long tailes field mouse (Apodemus sylavticus) (Rodentia Muridae) of Corsica
Libois, Roland ULg; Fons, Roger; Bordenave, Dominique

in Bonner Zoologische Beiträge (1993), 44(3-4), 147-163

The presence in Corsica of a field mouse is well known. Several authors have noted some of its morphological peculiarities but it was only recently (1980) that the presence of A. sylvaticus was ... [more ▼]

The presence in Corsica of a field mouse is well known. Several authors have noted some of its morphological peculiarities but it was only recently (1980) that the presence of A. sylvaticus was establblished with certainty. However, this evidence is based on a check of a limited number of individuals originating from a single locality. In order to generalize these observations, we performed o biochemical test on six Corsican mice caught in three distinct localites and a morpho biometrical study of 491 skulls. The results show that A. sylvaticus is spread all over the island and that A. flavicollis is probably absent. No sexual dimorphism was found but strong spatial variations in the cranial measurements were ividenced. There are far less important between the various Corsican sub samples than between the insular and the continenecal mice. The evolutionary and adaptive significance of the increase in size of insular mice is discussed in relation to the theory of island biogeography and to the present knowledge on the history of the mammalian settlement of the island. [less ▲]

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See detailCalcitonin for Prevention and Treatment of Osteoporosis
Reginster, Jean-Yves ULg

in American Journal of Medicine (1993), 95(5A), 44-47

There appears to be a consensus that 100 IU/day of nasally administered salmon calcitonin may prevent trabecular bone loss during the first year of the menopause. Strong evidence exists that half that ... [more ▼]

There appears to be a consensus that 100 IU/day of nasally administered salmon calcitonin may prevent trabecular bone loss during the first year of the menopause. Strong evidence exists that half that dose may also be sufficient to prevent trabecular bone loss and that higher doses (> or = 200 IU/day) induce a significant increase in spinal bone mineral content. Calcium supplements should be systemically administered when calcitonin is given, particularly at high doses. Rectal calcitonin seems also to be an efficient alternative in prevention of trabecular bone loss. Further studies are required to evaluate the effect of calcitonin in prevention of cortical bone loss. In established osteoporosis calcitonin may prevent further bone loss at trabecular and cortical sites. A similar benefit is obtained following parenteral or nasal administration of the drug. Long-term administration of nasal salmon calcitonin induces a significant dose-dependent gain of bone at the lumbar spine, whereas discontinuous therapy with a ratio of 1:2 or 2:3 between the treatment and nontreatment periods is the best regimen for cortical bone. Epidemiological, retrospective, and prospective studies provide a convergent network of evidence that calcitonin administration in osteoporosis contributes to reduce significantly the frequency of subsequent fractures, both in the spine and in the hip. Finally, in established osteoporosis, nasal calcitonin possesses a potent analgesic effect, reduces the duration of bed confinement, and decreases the number of concomitant analgesic medications. The well-demonstrated effects of nasal calcitonin permit it to be considered as a highly rational solution for the prevention and the treatment of postmenopausal osteoporosis. [less ▲]

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See detailMacromolecular engineering of polylactones and polylactides. 14. A 13C and 27Al NMR study of the effect of γ-butyrolactone on the structure of aluminum isopropoxide in toluene
Ropson, Nathalie; Dubois, Philippe; Jérôme, Robert ULg et al

in Macromolecules (1993), 26(24), 6378-6385

Solutions of Al isopropoxide in toluene have been investigated by C-13 and Al-27 NMR spectroscopy. Since Al(OiPr)3 is currently used as an initiator for the living polymerization of epsilon-caprolactone ... [more ▼]

Solutions of Al isopropoxide in toluene have been investigated by C-13 and Al-27 NMR spectroscopy. Since Al(OiPr)3 is currently used as an initiator for the living polymerization of epsilon-caprolactone, special attention has been paid to the effect of the monomer on the coordinative structure of Al(OiPr3) in toluene. Gamma-butyrolactone (BL) has been chosen as a nonpolymerizable model, representative of epsilon-caprolactone. The NMR spectra have been recorded at various concentrations of gamma-butyrolactone and temperatures. As a rule, Al(OiPr)3 is coordinatively aggregated in toluene in such a way that tetrameric and trimeric species are in equilibrium. Upon the addition of BL, this equilibrium is shifted toward the formation of an octahedric [Al(OiPr)3.3BL] mixed tetramer coexisting with [Al(OiPr)3]4 tetramers, the external tetrahedric Al atoms of which are coordinated with extra BL molecules. In the presence of a large excess of BL, only the mixed tetramer persists, which suggests that the single [Al(OiPr)3.3M] species would be the actual initiator for the ring-opening polymerization of cyclic monomers M, such as epsilon-caprolactone, lactides, glycolide, and cyclic anhydrides. [less ▲]

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See detailATMOS ATLAS-1 MEASUREMENTS OF SULFUR-HEXAFLUORIDE (SF6) IN THE LOWER STRATOSPHERE AND UPPER TROPOSPHERE
Rinsland, C. P.; Gunson, M. R.; Abrams, M. C. et al

in Journal of Geophysical Research (1993), 98(D11), 20491-20494

Vertical profiles of sulfur hexafluoride (SF6) in the lower stratosphere and upper troposphere have been retrieved from 0.01-cm-1 resolution infrared solar occultation spectra recorded by the Atmospheric ... [more ▼]

Vertical profiles of sulfur hexafluoride (SF6) in the lower stratosphere and upper troposphere have been retrieved from 0.01-cm-1 resolution infrared solar occultation spectra recorded by the Atmospheric Trace Molecule Spectroscopy (ATMOS) Fourier transform spectrometer during the ATLAS (Atmospheric Laboratory for Applications and Science) 1 shuttle mission of March 24 to April 2, 1992. Based on measurements of the unresolved absorption by the SF6 nu3 band Q branch at 947.9 cm-1, average SF6 volume mixing ratios and 1-sigma uncertainties of 3.20 +/- 0.54 parts per trillion by volume (pptv; 10(-12) ppv) at 200 mbar (approximately 11.8 km) declining to 2.86 +/- 0.29 pptv at 100 mbar (approximately 16.2 km) and 1.95 +/- 0.50 pptv at 30 mbar (approximately 23.9 km) have been retrieved. The profiles show no obvious dependence with latitude over the range of the measurements (eight occultations spanning 28-degrees-S to 54-degrees-S). Assuming an exponential growth model and applying a correction for the interhemispheric concentration difference, an average SF6 rate of increase of 8.7 +/- 2.2% per year, 2 sigma, between 12 and 18 km has been derived by fitting the present measurements, ATMOS measurements from the April-May 1985 Spacelab 3 mission, and balloon-borne IR measurements obtained in March 1981 and June 1988. [less ▲]

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See detailSurface concentration of chain ends in polystyrene determined by static secondary ion mass spectroscopy
Affrossman, S.; Hartshorne, M.; Jérôme, Robert ULg et al

in Macromolecules (1993), 26(23), 6251-6254

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See detailSite-directed mutagenesis of dicarboxylic acid residues of the penicillin-binding module of the Escherichia coli penicillin-binding protein 3
Goffin, Colette ULg; Ayala, J. A.; Nguyen-Distèche, Martine ULg et al

in FEMS Microbiology Letters (1993), 113(3), 247-251

The glutamic acid E396, aspartic acid D409 and glutamic acid E411 residues of the Escherichia coli penicillin-binding protein 3 were each converted into an alanine residue. As deduced from penicillin ... [more ▼]

The glutamic acid E396, aspartic acid D409 and glutamic acid E411 residues of the Escherichia coli penicillin-binding protein 3 were each converted into an alanine residue. As deduced from penicillin-binding and complementation experiments, none of these dicarboxylic acid residues is involved in the mechanism of acylation by penicillin and none of them is essential for the in vivo functioning of the PBP. The mutation E396, however, causes an increased thermolability of the protein. [less ▲]

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See detailFormation of P Cygni Line Profiles in Relativistically Expanding Atmospheres. II. The Effect of the Continuum Frequency Shape and Limb Darkening of the Core
Hutsemekers, Damien ULg

in Astrophysical Journal (1993), 417

Abstract image available at: http://adsabs.harvard.edu/abs/1993ApJ...417...97H

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See detailLongterm Photometry of Variables at ESO - Part Two - the Second Data Catalogue 1986-1990
Sterken, C.; Manfroid, Jean ULg; Anton, K. et al

in Astronomy and Astrophysics. Supplement Series (1993), 102

In this paper we present the second catalogue of photometric data in the Strömgren system obtained during the period October 1986- September 1990 in the framework of the Long-Term Photometry of Variables ... [more ▼]

In this paper we present the second catalogue of photometric data in the Strömgren system obtained during the period October 1986- September 1990 in the framework of the Long-Term Photometry of Variables (LTPV) program at the European Southern Observatory. The catalogue is available in computer readable form at the Centre de Données de Strasbourg. [less ▲]

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See detailInteractions between Active-Site-Serine Beta-Lactamases and Mechanism-Based Inactivators: A Kinetic Study and an Overview
Matagne, André ULg; Ghuysen, M. F.; Frère, Jean-Marie ULg

in Biochemical Journal (1993), 295((Pt 3)), 705-711

The interactions between three class A beta-lactamases and three beta-lactamase inactivators (clavulanic acid, sulbactam and olivanic acid MM13902) were studied. Interestingly, the interaction between the ... [more ▼]

The interactions between three class A beta-lactamases and three beta-lactamase inactivators (clavulanic acid, sulbactam and olivanic acid MM13902) were studied. Interestingly, the interaction between the Streptomyces cacaoi beta-lactamase and clavulanate indicated little irreversible inactivation. With sulbactam, irreversible inactivation was found to occur with the three studied enzymes, but no evidence for transiently inactivated adducts was found. Irreversible inactivation of the S. albus G and S. cacaoi enzymes was particularly slow. With olivanate, irreversible inactivation was also observed with the three enzymes, but with the S. cacaoi enzyme, no hydrolysis could be detected. A tentative summary of the results found in the literature is also presented (including 6 beta-halogenopenicillanates), and the general conclusions underline the diversity of the mechanisms and the wide variations of the rate constants observed when class A beta-lactamases interact with beta-lactamase inactivators, in agreement with the behaviours of the same enzymes towards their good and poor substrates. [less ▲]

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See detailMixmaster universe in fourth-order gravity theories
Cotsakis, S.; Demaret, Jacques; De Rop, Yves ULg et al

in Physical Review. D : Particles and Fields (1993), 48

We analyze the behavior of the Bianchi type-IX cosmological model in the full fourth-order theory of gravity in four space-time dimensions on approach to the singularity both analytically and numerically ... [more ▼]

We analyze the behavior of the Bianchi type-IX cosmological model in the full fourth-order theory of gravity in four space-time dimensions on approach to the singularity both analytically and numerically. By directly analyzing the full fourth-order field equations we prove explicitly that the Belinski-Khalatnikov-Lifshitz (BKL) analytic solution (and the accompanying bounce law) is also a solution to the more general case that we consider. But it appears to be nongeneric, because a perturbation analysis shows that power-law Kasner asymptotes are unstable on approach to the singularity. On the other hand, we find that the model possesses a stable isotropic monotonic power-law asymptotic solution and accordingly we show that there is a general solution which is nonchaotic near the space-time singularity. Numerical experiments confirm the existence of such a behavior. The inclusion of matter fields does not alter the evolution in the neighborhood of the singularity. The role of space-time dimensionality on the chaotic evolution of the mixmaster universe in these theories is also spelled out. In particular, we show that it is impossible to build a mixmaster universe in space-time dimensions higher than four in the full fourth-order gravity theory based on the BKL approximation scheme. [less ▲]

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See detailEnhancement of Tumorigenicity of Human Breast Adenocarcinoma Cells in Nude Mice by Matrigel and Fibroblasts
Noël, Agnès ULg; Gillet, Marie-Claire ULg; Purnell, G. et al

in British Journal of Cancer (1993), 68(5), 909-15

The failure of MCF7 cells to induce the formation of tumours after sub-cutaneous inoculation into athymic nude mice can be obviated by the simultaneous injection of an extract of basement membrane ... [more ▼]

The failure of MCF7 cells to induce the formation of tumours after sub-cutaneous inoculation into athymic nude mice can be obviated by the simultaneous injection of an extract of basement membrane proteins (matrigel). Tumour growth is promoted and the latency period is low (2 to 4 weeks). In the absence of matrigel, the simultaneous inoculation of fibroblasts and MCF7 cells also resulted in the development of tumours, but with a longer latency period (about 2 months). The tumorigenic synergy between matrigel and fibroblasts was evidenced by co-inoculating MCF7 cells MDA-MB 231 cells with fibroblasts and matrigel. This co-inoculation decreased the delay of appearance of the tumours and/or accelerated the tumour growth, depending upon the number of fibroblasts injected. Repeated injections of fibroblasts conditioned medium, at the site of inoculum of tumour cells also enhanced tumour growth, suggesting the involvement of soluble factors secreted by fibroblasts. Histologically, tumours induced by co-inoculation of tumour cells and fibroblasts contained more stromal structures including vimentin-positive cells, fibronectin and interstitial collagens. These data suggest that human tumours may be reconstituted and grown in athymic nude mice using basement membrane components and fibroblasts as inductors. [less ▲]

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See detailUse of G.I.S. and remote sensing in hydrological model for impact study of land cover change in a malagasy rural basin
Randriamaherisoa, Alain; Binard, Marc ULg; Persoons, Etienne

in International Journal "Advances in Remote Sensing" (1993), 2(3), 154-164

A conceptual distributed-based model has been developed for flood simulation and forecasting. The model structure consists of a square grid network, in analogy with the raster form of numerical maps. The ... [more ▼]

A conceptual distributed-based model has been developed for flood simulation and forecasting. The model structure consists of a square grid network, in analogy with the raster form of numerical maps. The square-pixel is the analysis unit for hydrologie balance in relation with physi-cal characteristics. Punctual and cartographical data sources are used to characterize each mesh. Aerial photo-graphy and satellite imagery give information about land use. Topographical characteristics are obtained from Digi-tal Terrain Model (DTM). Soil type can be numerized to help in estimating the drainage condition. Hydrological data are distributed in accordance with the Thiessen's polygons or the associated sub-basin. All the data are handled by the GIS part in order to classify the surface runoff potential of all meshes. This procedure allow to consider the physical characteristics and the spatial vari-ability of the parameters at small scale, to manage special devices like storm basins, pumping stations and spillways and to do a quick study of the spatio-temporal evolution of the characteristics. Impact analysis of land cover modi-fications on the river flow regime is therefore possible. In one large rural Malagasy watershed, rince the 1960's, several waterworks were achieved in order to struggle against the flooding of the upstream fertile plain (subject of various developments). Meanwhile, the forest of the basin hillslopes was and still strongly claimed for pluvial rice crop, which is necessary for the subsistence of a fast growing population. The main object of this work is to study the hydrological impacts of these changes of land use on the watershed behaviour and to forecast the basin water regime evolution. [less ▲]

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See detailJean-Pierre Verheggen, Les Folies-Belgères
Durand, Pascal ULg

in Textyles : Revue des Lettres Belges de Langue Française (1993), 9

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See detailPhysiologie de la femme enceinte et facteurs de risques
Foidart, Jean-Michel ULg

in Contraception, Fertilite, Sexualité (1992) (1993), 21(11), 811-5

Physiological adaptations of the pregnant woman involve the circulatory, respiratory, digestive, renal, endocrine and metabolic systems. Their precise knowledge allows the clinician to verify the quality ... [more ▼]

Physiological adaptations of the pregnant woman involve the circulatory, respiratory, digestive, renal, endocrine and metabolic systems. Their precise knowledge allows the clinician to verify the quality of the adaptation of the pregnant woman and to avoid unnecessary treatment of physiological changes misconsidered as pathological changes in reference to prepregnancy standards. [less ▲]

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See detailAdjuvant postoperative accelerated hyperfractionated radiotherapy in rectal cancer : a feasability study
Coucke, Philippe ULg; Cuttat, J-F; Mirimanoff, R-O

in International Journal of Radiation, Oncology, Biology, Physics (1993), 24(4), 885-889

To assess the acute toxicity and hence feasibility of postoperative hyperfractionated accelerated radiotherapy in rectal cancer. METHODS AND MATERIALS: Twenty patients were submitted to accelerated ... [more ▼]

To assess the acute toxicity and hence feasibility of postoperative hyperfractionated accelerated radiotherapy in rectal cancer. METHODS AND MATERIALS: Twenty patients were submitted to accelerated hyperfractionated radiotherapy after resection of rectal cancer. A total dose of 48 Gy was given in 3 weeks. Two fractions of 1.6 Gy were used with a mean interfraction interval of at least 6 hours. The pelvic volume was treated by a four-field box technique using a linear accelerator (6-18 MV). Acute toxicity was assessed once per week. Small bowel and skin toxicity were scored according to the criteria of the World Health Organization. Bladder toxicity was scored according to the criteria of the Radiation Therapy Oncology Group. RESULTS: All the patients underwent the treatment as planned except one. No patient presented grade 3 or 4 bladder toxicity. There was only one patient who complained from grade 3 skin toxicity at the end of the treatment. Fourteen patients had some degree of intestinal toxicity. This was the most frequently occurring acute side-effect. Only two out of the fourteen patients had intestinal toxicity exceeding grade 2. CONCLUSION: Hyperfractionated accelerated radiotherapy on a pelvic volume is feasible [less ▲]

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See detailControl of Pulsatile Secretion of Gonadotrophin Releasing Hormone from Hypothalamic Explants
Bourguignon, Jean-Pierre ULg; Gerard, Arlette ULg; Alvarez Gonzalez, Maria-Luz ULg et al

in Human Reproduction (1993), 8 Suppl 2(NULL), 18-22

We have studied the secretion of gonadotrophin releasing hormone (GnRH) from hypothalamic explants of male rats at different ages in an attempt to delineate the neuroendocrine mechanism of the onset of ... [more ▼]

We have studied the secretion of gonadotrophin releasing hormone (GnRH) from hypothalamic explants of male rats at different ages in an attempt to delineate the neuroendocrine mechanism of the onset of puberty. In this paper, we review some of our recent studies and we provide evidence of a dual control played by receptors to neuroexcitatory amino acids. We showed previously that isolated explants of rat hypothalamus could secrete GnRH in a pulsatile manner. The onset of puberty was characterized by a 2-fold increase in frequency of GnRH secretory pulses. This reduction of the interval between GnRH pulses involved an inhibitory autofeedback effect of GnRH on the pulse generator which was shut off following a secretory episode. This period of refractoriness was longer before puberty than after the onset of puberty. Activation of receptors to neuroexcitatory amino acids (N-methyl-D-aspartate; NMDA-type) was involved in the mechanism of pulsatile GnRH secretion. Striking developmental changes in NMDA-receptor-mediated GnRH secretion were demonstrated with a maximal activity around the time of the onset of puberty. Similar changes occurred in orchidectomized animals, indicating that this maturational process was gonad-independent. While evidence accumulated that NMDA receptors were involved in a stimulatory control of GnRH secretion, we found that NMDA receptors mediated an inhibitory effect on GnRH secretion. This inhibitory effect was very potent in the immature hypothalamus and it showed a marked reduction in potency before onset of puberty.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailTowards a rational utilization of satellite imagery for Lisbon's metropolitan planning
Binard, Marc ULg; Nadasdi, Istvan

in EARSeL International Journal "ADVANCES IN REMOTE SENSING" (1993), 2(3), 130-137

The knowledge of the actual structure and 'intensity of land cover is a fundamental information for the urban planning. Some aspects of the seeked information can be extracted from satellite imagery. This ... [more ▼]

The knowledge of the actual structure and 'intensity of land cover is a fundamental information for the urban planning. Some aspects of the seeked information can be extracted from satellite imagery. This presentation gives some exemples over the Metropolitan area of Lisbon. First, an image segmentation is accomplished over an XS3 band. This process leads to a rather valid subdivision of the region in morphological units. Secondly, the urban and vegetal categories, issued from a land cover classification, are modeled in the form of statistical surfaces. The statistical surfaces take advantage of the analytical power of a raster solving approach. Fi-nally, the urban and vegetal intensity surfaces are merged. The result can be considered as an attempt of ecozoning the considered region. The paper discuss also the possibilities of using remotly sensed data for urban planning. [less ▲]

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See detailAcute Suppression of Gonadotropin-Releasing Hormone Secretion by Insulin-Like Growth Factor I and Subproducts: An Age-Dependent Endocrine Effect
Bourguignon, Jean-Pierre ULg; Gerard, Arlette ULg; Alvarez Gonzalez, Maria-Luz ULg et al

in Neuroendocrinology (1993), 58(5), 525-30

Using rat hypothalamic explants, we showed previously that activation of N-methyl-D-aspartate (NMDA) receptors was involved in the mechanism of gonadotropin-releasing hormone (GnRH) secretion. (1-3 ... [more ▼]

Using rat hypothalamic explants, we showed previously that activation of N-methyl-D-aspartate (NMDA) receptors was involved in the mechanism of gonadotropin-releasing hormone (GnRH) secretion. (1-3)Insulin-like growth factor I (IGF-I), the N-terminal tripeptide of IGF-I, was suggested to be a possible antagonist at NMDA receptors. Here, we study the effects of IGF-I and its subproducts, (1-3)IGF-I and (4-70)IGF-I, either given in vivo as a single subcutaneous injection or used in vitro, on the secretion of GnRH by hypothalamic explants. At the three ages studied (15, 25 and 50 days), (4-70)IGF-I does not show any effect. At 50 days, the in vivo administration or the in vitro use of IGF-I results in a dose-related inhibition of the GnRH secretion induced by veratridine, a depolarizing agent. In addition, the spontaneous pulsatile secretion of GnRH in vitro is transiently suppressed after the in vivo administration of IGF-I. (1-3)IGF-I results in an inhibitory effect similar to that of IGF-I. At 25 days, IGF-I and (1-3)IGF-I show the same effects as at 50 days though higher concentrations are required. At 15 days, IGF-I does not show any effect whereas a potent inhibition of GnRH secretion is observed using (1-3)IGF-I either in vivo or in vitro. At all ages, the effects of (1-3)IGF-I parallel those of AP-5, a competitive antagonist at NMDA receptors.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

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See detailAndré Blavier, Occupe-toi d’homélies
Durand, Pascal ULg

in Textyles : Revue des Lettres Belges de Langue Française (1993), 9

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