References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailStructural and functional properties of apolipoprotein B in chemically modified low density lipoproteins.
Vanderyse, L.; Devreese, A. M.; Baert, J. et al

in Atherosclerosis (1992), 97(2-3), 187-99

The structural and compositional changes occurring during in vitro chemical modification of apolipoprotein B-100 (apo B), the apolipoprotein component of low density lipoproteins (LDL), were investigated ... [more ▼]

The structural and compositional changes occurring during in vitro chemical modification of apolipoprotein B-100 (apo B), the apolipoprotein component of low density lipoproteins (LDL), were investigated in this study. The functional properties of chemically modified apo B and especially its potential to induce accumulation of cholesterol esters in macrophages were related to the structural changes of apo B. Acetylation, maleylation or malondialdehyde conjugation did not significantly affect the lipid composition of LDL. However, the unsaturated cholesteryl esters content, especially that of cholesteryl arachidonate was significantly decreased through Cu-oxidation. The number of reactive lysine residues in apo B was decreased by Cu-catalyzed LDL oxidation, acetylation, maleylation and by malondialdehyde conjugation. The number of free cysteines decreased from six in native apo B-100 to three in Cu-oxidized LDL. The tryptophan fluorescence intensity decreased most in malondialdehyde-conjugated LDL and in Cu-oxidized LDL, compared with acetylated and maleylated LDL. The secondary structure of native and chemically modified LDL was measured by attenuated total reflection infrared spectroscopy and by circular dichroism. No significant changes were observed in the secondary structure of any of the modified LDL. These data suggest that neither acetylation, malondialdehyde treatment or even Cu-oxidation substantially altered the secondary structure of apo B, in spite of significant modifications in the primary structure. Incubation of chemically modified LDL with J774 macrophages induced an accumulation of cellular cholesteryl esters and foam cell formation. The highest cholesterol accumulation was induced after malondialdehyde treatment of LDL. These data suggest that the cellular uptake and accumulation of modified LDL is not modulated by changes in the apo B structure. Rather it seems dependent upon the net charge of the apo B protein and probably involves the modification of critical lysine residues. [less ▲]

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailMacromixing versus hydrodynamics in trickle-flow columns
Crine, Michel ULg; Marchot, Pierre ULg; Lekhlif, B. et al

in Chemical Engineering Science (1992), 47

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailVoyages into Otherness: Cambridge and Lucy
Ledent, Bénédicte ULg

in Kunapipi : Journal of Postcolonial Writing (1992), 14(2), 53-63

Detailed reference viewed: 111 (6 ULg)
Peer Reviewed
See detailManagement of non-insulin-dependent diabetes mellitus.
Lefebvre, Pierre ULg; Scheen, André ULg

in Drugs (1992), 44 Suppl 3

The initial management of non-insulin-dependent diabetes mellitus (NIDDM) should include patient education, dietary counselling and, when feasible, individualised physical activity. It is only when such ... [more ▼]

The initial management of non-insulin-dependent diabetes mellitus (NIDDM) should include patient education, dietary counselling and, when feasible, individualised physical activity. It is only when such measures fail that drug therapy should be considered. Dietary management of NIDDM includes a restriction in calories, and these should be appropriately distributed as carbohydrates, lipids and proteins. Supplementation of the diet with soluble fibre and supplementation with magnesium salts if hypomagnesaemia is demonstrated, is recommended. However, supplementation with fish oils or with fish oil-derived omega-3 fatty acids is not currently recommended. Oral drug therapies used in NIDDM include sulphonylurea derivatives, which are a first-line treatment in patients who are not grossly obese, metformin, which is the treatment of choice for obese patients, and alpha-glucosidase inhibitors such as acarbose, which are used mainly to reduce postprandial blood glucose peaks. These types of drugs can be used alone or in combination. Insulin therapy may be required to achieve adequate control of blood glucose levels in some patients. In several instances, it is suggested that insulin therapy be combined with sulphonylureas (essentially when residual insulin secretion is present), with metformin, or with alpha-glucosidase inhibitors. The treatment of disorders associated with NIDDM, such as obesity, hypertension or hyperlipidaemia, requires particular attention in diabetic patients, since some drugs can adversely affect glycaemic control. Oral drugs for the treatment of NIDDM include sulphonylurea derivatives used in first-line treatment in patients who are not grossly obese, metformin, which is often the treatment of choice for obese patients and, more recently, the alpha-glucosidase inhibitors, such as acarbose, which are effective in reducing the postprandial rise in blood glucose. [less ▲]

Detailed reference viewed: 63 (1 ULg)
Full Text
Peer Reviewed
See detailLa pression artérielle chez l'adolescent : tables de référence concernant la population liégeoise.
Saint-Remy, Annie ULg; Rorive, Georges ULg; Geubelle, Fernand

in Revue Médicale de Liège (1992), 47(1), 17-24

Identifier précocement les individus exposés au risque de développer une hypertension artérielle dans le futur et appliquer des mesures préventives dès le plus jeune âge devraient constituer une ... [more ▼]

Identifier précocement les individus exposés au risque de développer une hypertension artérielle dans le futur et appliquer des mesures préventives dès le plus jeune âge devraient constituer une alternative au traitement pharmacologique de l'hypertension artérielle permanente chez l'adulte. L'exploitation d'une étude épidémiologique prospective conduite dans la Province de Liège a permis d'établir des valeurs de référence de la pression artérielle des adolescents et de souligner les particularités de la distributon et des déterminants du niveau de pression artérielle entre 12 et 17 ans. [less ▲]

Detailed reference viewed: 272 (1 ULg)
Full Text
Peer Reviewed
See detailPhotoionization Mass Spectrometry of Kinetic Energy-selected ions. The Translational Energy Distribution of N+/N2 in the Inner-shell Ionization energy range.
Locht, Robert ULg; Denzer, W.; Rühl, E. et al

in Chemical Physics (1992), 160

An ion retarding potential difference (IRPD) method has been used to investigate the ion yield and the kinetic energy distributions of N+/N2 produced by photoionization mass spectrometry using synchrotron ... [more ▼]

An ion retarding potential difference (IRPD) method has been used to investigate the ion yield and the kinetic energy distributions of N+/N2 produced by photoionization mass spectrometry using synchrotron radiation. Photoion yield curves of energy selected N+ ions are deduced. Translational energy distributions of N+ at the energies of the N(1s)->pi*, N(1s)->(nl)1 and above the N(1s)-1 threshold are determined. Comparison is made with previous photoion-photoelectron coincidence work using time-of-flight (TOF) measurements. [less ▲]

Detailed reference viewed: 33 (0 ULg)
See detailPrécision fonctionnelle du schéma de structure communal
Collette, Jean-Pierre ULg; Goossens, Marc ULg; Hanocq, Philippe ULg

in Environnement et Société (1992), 9/10

Examen comparé des notions de "fonctions" et de "densités" dans les divers documents planologiques élaborés à différentes échelles territoriales.

Detailed reference viewed: 40 (8 ULg)
Peer Reviewed
See detailDifferential effects of picrotoxin and RO 15-1788 on high and low ethanol concentrations on rat locus coeruleus in vitro.
Verbanck, P. M.; Seutin, Vincent ULg; Massotte, Laurent ULg et al

in European Journal of Pharmacology (1992), 211(1), 15-21

In an in vitro electrophysiological single-cell recording model, ethanol had an inhibitory effect on locus coeruleus (LC) neurons at both low (0.1 mmol/l) and high (500 mmol/l) concentrations. In order to ... [more ▼]

In an in vitro electrophysiological single-cell recording model, ethanol had an inhibitory effect on locus coeruleus (LC) neurons at both low (0.1 mmol/l) and high (500 mmol/l) concentrations. In order to test if the benzodiazepine-GABA (gamma-aminobutyric acid) receptor complex could be implicated in this effect, we tested the interaction of these ethanol concentrations with picrotoxin (100 mmol/l) and RO 15-1788 (10 nmol/l). RO 15-1788 reversed the inhibitory effect induced by ethanol 500 mmol/l, but not by ethanol 0.1 mmol/l; picrotoxin reversed the effects of both concentrations. This indicates that the mechanisms of action of ethanol on LC neurons are not the same for high and low concentrations. Furthermore, the effect of concentrations related to a behavioral effect (greater than 10 mmol/l) was reversed by a low-calcium medium that abolishes transmitter release. Therefore, the inhibition induced by ethanol 500 mmol/l seems to be due to the release of an endogenous benzodiazepine-like compound. [less ▲]

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailInfluence of the Counterpoise Correction on the Optimized Relativi Degrees of Freedom in the H-Bonded Complex Water-Formamide
Dehareng, Dominique ULg; Dive, Georges ULg; Ghuysen, Jean-Marie ULg

in Theoretica Chimica Acta (1992), 81(4-5), 281-290

The correction of the basis set superposition error by the counterpoise method has been investigated at the SCF level for the weak H-bonded water-formamide complex and the results have been compared with ... [more ▼]

The correction of the basis set superposition error by the counterpoise method has been investigated at the SCF level for the weak H-bonded water-formamide complex and the results have been compared with the uncorrected results at the SCF, post SCF and semi-empirical AM1 and MNDO levels. Our particular concern has been the determination of the three optimized relative degrees of freedom and the relative stability of three C(s) geometrical conformations. The conclusions are that the counterpoise correction weakly conditions the variation in the degrees of freedom and the relative stabilities of the three conformers. The correction is obviously inadequate to describe intramolecular deformation. [less ▲]

Detailed reference viewed: 18 (1 ULg)
See detailGuglielmo d'Inghilterra.
Moreno, Paola ULg

in Medioevo Romanzo (1992)

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailEtude préliminaire du comportement d'hybridation de Barbus barbus (L.) et de Barbus meridionalis (Risso) en aquarium.
Jeandarme, J.; Poncin, Pascal ULg; Berrebi, P.

in Cahiers d'Ethologie Appliquée (1992), 11(4), 519-528

Detailed reference viewed: 22 (2 ULg)
Peer Reviewed
See detailCoupled thermo-mechanical-metallurgical analysis during the cooling of steel pieces
Habraken, Anne ULg; Bourdouxhe, M.

in European Journal of Mechanics A : Solids (1992), 11(3), 381-402

Detailed reference viewed: 16 (8 ULg)
Peer Reviewed
See detailAutomatic adaptive remeshing for numerical simulations of metalforming
Dyduch, M.; Habraken, Anne ULg; Cescotto, Serge ULg

in Computer Methods in Applied Mechanics & Engineering (1992), 101

Detailed reference viewed: 10 (3 ULg)
Full Text
Peer Reviewed
See detailVaginoplasty using amniotic membranes in cases of vaginal agenesis or after vaginectomy.
NISOLLE, Michelle ULg; Donnez, Jacques

in Journal of Gynecologic Surgery (1992), 8(1), 25-30

Various treatments have been proposed for vaginal agenesis. The authors describe successful procedures using amniotic membranes as a graft on vaginoplasties. The amnion was not stripped from the chorion ... [more ▼]

Various treatments have been proposed for vaginal agenesis. The authors describe successful procedures using amniotic membranes as a graft on vaginoplasties. The amnion was not stripped from the chorion. The results showed the vagina to be well formed and of normal depth and caliber. [less ▲]

Detailed reference viewed: 17 (10 ULg)
See detailBiologie de Caryedon pallidus (Oliv., 1790) (Col., Bruchidae), ravageur des graines de Cassia occidentalis (L.).
Lienard, V.; Seck, D.; Haubruge, Eric ULg et al

in Bulletin & Annales de la Societe Royale Belge d'Entomologie (1992), 128(10-12),

Detailed reference viewed: 17 (1 ULg)
See detailAvant-propos. Rapport préliminaire sur les 1re et 2e campagnes de fouille à Tell Amarna (Syrie)
Tunca, Önhan ULg

in Chronique archéologique en Syrie 1 (1992)

Detailed reference viewed: 11 (1 ULg)
Full Text
See detailUn Coran liégeois
Martin, Aubert ULg; Bauden, Frédéric ULg

in La Vie Wallonne (1992), 56(417-418), 5-20

Detailed reference viewed: 70 (18 ULg)
Full Text
Peer Reviewed
See detailCerebral and extracerebral hemodynamics in healthy and sick human neonates
Battisti, Oreste ULg; Armengol, A.; Withofs, L. et al

in Circulation et Métabolisme du Cerveau (1992), 9

Detailed reference viewed: 17 (9 ULg)
See detailStudy of a new presumed mitochondrial carrier, the product of the yeast RIM 2 gene
Hellin, E.; Van Dyck, E.; Duyckaerts, Claire ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailValidation of the monofrequency forced oscillation technique for pulmonary function investigation in calves : an in vitro and in vivo study
Reinhold, Petra; Close, Roland; Lekeux, Pierre ULg

in Research in Veterinary Science (1992), 53(2), 165-171

This study was to investigate whether the monofrequency forced oscillation (MFO) technique could be accurately used for pulmonary function testing in calves. The airflow resistance measured by this ... [more ▼]

This study was to investigate whether the monofrequency forced oscillation (MFO) technique could be accurately used for pulmonary function testing in calves. The airflow resistance measured by this technique was compared to the resistance measured by the classical reference method by an in vitro study, using an artificial lung model, and by an in vivo study, using 11 healthy calves. The effect of the reference impedance of this oscillation equipment was also investigated. The results show linear relationships (r2 > 0.924, P < 0.001) in the resistance ranges 0 to 0.7 kPa litre-1 s and 0 to 1.0 kPa litre-1 s with a reference impedance of 1.0 kPa litre-1 s and 2.0 kPa litre-1 s, respectively. The MFO resistance values lower and higher than 0.4 kPa litre-1 s are slightly overestimated and underestimated, respectively. It was shown that, if some technical requirements are met, the MFO technique is a simple, reproducible, fast and accurate method which allows measurement of airflow resistance even in field conditions. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Peer Reviewed
See detailEtude ultrastructure de l'organisation du nucléoïde du virus de la varicelle et du zona
Schoonbroodt, Sonia; Piette, Jacques ULg; Rentier, Bernard ULg

in Bulletin de la Société Royale des Sciences de Liège (1992), 60(6), 373-383

Detailed reference viewed: 18 (0 ULg)
Peer Reviewed
See detailBioconversion of vanillin into vanillic acid by Pseudomonas fluorescens, strain BTP9. I. Cell reactors and mutants study.
Baré, G.; Gerard, J.; Jacques, Ph. et al

in Applied Biochemistry and Biotechnology (1992), 34/35

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailHighly sensitive immunodetection of DNA on sections with exogenous terminal deoxynucleotidyl transferase and non-isotopic nucleotide analogues.
Thiry, Marc ULg

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (1992), 40(3), 411-9

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and ... [more ▼]

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and various non-isotopic nucleotide analogues. The labeled nucleotides bound to the surface of ultra-thin sections were then visualized by an indirect immunogold labeling technique. The resulting labeling pattern was strongly dependent on the divalent cation used in the TdT medium. The method revealed with great precision the specific DNA-containing structures within Ehrlich tumor cells, even where DNA was present in very low amounts. The method is compatible with all usual fixation and embedding procedures and can be combined with cytochemical methods. The in situ TdT method provides a very useful tool for pinpointing the precise location of DNA within biological material at the ultrastructural level. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailStructure of the tilapia (Oreochromis mossambicus) prolactin I gene
Swennen, D.; Poncelet, A. C.; Sekkali, B. et al

in DNA & Cell Biology (1992), 11(9), 673-84

The tilapia (Oreochromis mossambicus) prolactin-I (PRL-I) gene has been cloned and sequenced. Its transcript (3,677 bases long) begins with a guanine and is organized in five exons and four introns like ... [more ▼]

The tilapia (Oreochromis mossambicus) prolactin-I (PRL-I) gene has been cloned and sequenced. Its transcript (3,677 bases long) begins with a guanine and is organized in five exons and four introns like the other known prolactin genes. Analysis of the 1,555-bp 5'-flanking region suggests that pituitary-specific expression of the gene could be regulated through a trans-factor related to the mammalian pituitary-specific factor Pit-1. Two potential binding sites for such a factor were found in the first intron, suggesting a possible regulatory role for this region. Moreover, two potential Z-DNA regions are located at positions -837 to -812 and -246 to -179 from the transcription start site. These two regions could play an important role in the regulation of PRL gene expression. [less ▲]

Detailed reference viewed: 27 (1 ULg)
See detail«Le Testament Maistre Jehan de Meun». Un caso letterario.
Moreno, Paola ULg

in Medioevo Romanzo (1992)

Detailed reference viewed: 9 (0 ULg)
Peer Reviewed
See detailDam treatment with insulin-like growth factor-I monoclonal antibodies induce an alteration of fetal development
Renaville, Robert ULg; Devolder, Anne; Sneyers, Myriam et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Detailed reference viewed: 3 (0 ULg)
Peer Reviewed
See detailC.R. de W.D. PADEN, The Voice of the Trobairitz, Perspectives on the Women Troubadours
Henrard, Nadine ULg

in Moyen Age (Le) (1992), XCVIII

Detailed reference viewed: 31 (3 ULg)
Peer Reviewed
See detailMort, mentalité et tradition à la lumière des ballades de Terre-Neuve
Peere, Isabelle ULg

in Canadian Folklore Canadien (1992), 14(2), 137-58

A talerole analysis of prominent Newfoundland ballad and narrative song records on the theme of death highlighting coherent meaning throughout the different layers of the local song tradition, i.e. an ... [more ▼]

A talerole analysis of prominent Newfoundland ballad and narrative song records on the theme of death highlighting coherent meaning throughout the different layers of the local song tradition, i.e. an exclusive and constant preoccupation with tragic, sudden, premature and violent death as an inspiration to courage and responsibility rather than despair or resignation. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detail2- and 4-[18F]fluorotropapride, two specific D2 receptor ligands for positron emission tomography: N.C.A. syntheses and animal studies.
Damhaut, Philippe; Cantineau, Robert; Lemaire, Christian ULg et al

in International Journal of Radiation Applications and Instrumentation. Part A : Applied Radiation and Isotopes (1992), 43(10), 1265-74

Tropapride, (exo)-2,3-dimethoxy-N-[8-(phenylmethyl)-8- azabicyclo[3.2.1]oct-3-yl]benzamide hydrochloride, has been labeled with fluorine-18 at the 2- and 4-positions of its benzylic group. Two synthetic ... [more ▼]

Tropapride, (exo)-2,3-dimethoxy-N-[8-(phenylmethyl)-8- azabicyclo[3.2.1]oct-3-yl]benzamide hydrochloride, has been labeled with fluorine-18 at the 2- and 4-positions of its benzylic group. Two synthetic pathways were investigated: the first one required the alkylation of the norbenzyl precursor with 2- or 4-[18F]fluorobenzyl bromide (radiochemical yield of 5% EOB, 180 min); the second method consisted of a reductive amination of norbenzyl tropapride with 2- or 4-[18F]fluorobenzaldehyde (20% EOB, 110 min). In both cases, the specific activity was found to be greater than 1 Ci/mumol (EOS). Animal studies in rats showed the percentage of the injected dose localizing in the whole brain to be 0.6 +/- 0.09 and 0.2 +/- 0.03 at 2 h post injection for the para- and the ortho-[18F]fluoro analogs of tropapride respectively. Cerebral biodistribution studies showed at 4 h a striatum uptake of 5 +/- 0.7% of the injected dose per gram of striatum for the para derivative with a low fixation into the frontal cortex and the cerebellum (% ID/g FC < 0.4 and % ID/g Cb < 0.3). The selectivity of 4-[18F]fluorotropapride for D2 dopaminergic sites was demonstrated through blocking experiments with ketanserin, spiperone and halopemide. The saturability was confirmed by the use of variable specific activities. These preliminary results showed that 4-[18F]fluorotropapride can be considered as a potent radiopharmaceutical for the study of the dopaminergic system with PET. [less ▲]

Detailed reference viewed: 30 (13 ULg)
Full Text
Peer Reviewed
See detailLocindus, le jeu de la localisation industrielle
Merenne-Schoumaker, Bernadette ULg; Bianchet, Bruno; Demeuse, Yves

in Bulletin de la Société Géographique de Liège (1992), (28), 41-56

Any location decision takes into account many variables and processes. In order to apprehend them, we propose a "simulation game". Indeed, this one presents the great merit of putting the student in a ... [more ▼]

Any location decision takes into account many variables and processes. In order to apprehend them, we propose a "simulation game". Indeed, this one presents the great merit of putting the student in a problematic situation and leads him to understand certain attitudes. However, a good finality information, and on the other hand, a fundamental learning. Theoretical knowledge so envisaged will permit a better understanding of the decision process and will improve its efficency. [less ▲]

Detailed reference viewed: 49 (0 ULg)
Peer Reviewed
See detailSubstituabilité partielle des facteurs et efficacité-coût. L'exemple du transport urbain et vicinal belge.
Delhausse, Bernard; Thiry, Bernard; Perelman, Sergio ULg

in Economie et Prévision (1992)

Le but de l’article est de mesurer les niveaux d’efficacité d’entreprises de transport, urbain et interurbain, de passagers. Le modèle théorique permet de combiner des facteurs simultanément ... [more ▼]

Le but de l’article est de mesurer les niveaux d’efficacité d’entreprises de transport, urbain et interurbain, de passagers. Le modèle théorique permet de combiner des facteurs simultanément complémentaires et substituables. L’importance des liens de complémentarité entre certains facteurs de production apparaît. Les calculs des niveaux d’efficacité font ressortir l’amélioration des firmes concernées au fil du temps. [less ▲]

Detailed reference viewed: 12 (0 ULg)
Peer Reviewed
See detailPulmonary arterial impedance and right ventricular function in a canine model of septic shock
D'Orio, Vincenzo ULg; MARTINEZ, Christophe ULg; SAAD, G et al

in Intensive Care Medicine (1992), 18-S2

Detailed reference viewed: 10 (2 ULg)
Peer Reviewed
See detailExamens electrophysiologiques dans la migraine.
Schoenen, Jean ULg

in Pathologie Biologie (1992), 40(4), 293-304

This article is a critical review of standard electroencephalography (EEG), brain mapping, evoked potential, and electromyography (EMG) studies carried out in various forms of migraine during and between ... [more ▼]

This article is a critical review of standard electroencephalography (EEG), brain mapping, evoked potential, and electromyography (EMG) studies carried out in various forms of migraine during and between attacks. With the exception of contingent negative variation, the exteroceptive silent period of the temporalis muscle, and possibly fast activity in response to visual stimuli, which are useful for the differential diagnosis of functional headache, the main value of electrophysiologic studies is to provide insight into the pathophysiology of the disease. Results of the different methods consistently indicate that the brain of migraine patients is characterized by hypersensitivity to some forms of stimuli between attacks and by, often focal, hypoactivity during attacks. [less ▲]

Detailed reference viewed: 22 (0 ULg)
Peer Reviewed
See detailEffect of endotoxin insult on critical closure in the canine pulmonary vasculature
D'Orio, Vincenzo ULg; FATEMI, M; MENDES, P et al

in Applied Cardiopulmonary Pathophysiology [=ACP] (1992), 4

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailEnvironmental monitoring at FUL
De Backer, Louis W.; Andre, Philippe ULg; Nicolas, Jacques ULg

in Journal on automatic control (1992), 33

The paper presents the research and teaching activities of Fondation Universitaire Luxembourgeoise (Arlon) and more particularly in the domain of Environmental Monitoring. Particular attention is given to ... [more ▼]

The paper presents the research and teaching activities of Fondation Universitaire Luxembourgeoise (Arlon) and more particularly in the domain of Environmental Monitoring. Particular attention is given to "intelligent measurement, bio-sensors and event forecast algorithms. The team of researchers tries to integrate the three steps of monitoring: measurement, data processing and decision making support. It develops short-term fog forecasting tools, water quality sensors, soil water status quality assessment techniques and uses models describing soil and water transfers in soils and artificial intelligence techniques applied to energy management in buildings. [less ▲]

Detailed reference viewed: 23 (1 ULg)
Full Text
Peer Reviewed
See detailLCAT activation properties of apo A-I CNBr fragments and conversion of discoidal complexes into spherical particles.
Vanloo, B.; Taveirne, J.; Baert, J. et al

in Biochimica et Biophysica Acta (1992), 1128(2-3), 258-66

We studied the substrate properties of the phospholipid-cholesterol-apolipoprotein complexes generated with apo A-I, apo A-I-CNBr fragments, apo A-II and apo A-IV for cholesterol esterification by the ... [more ▼]

We studied the substrate properties of the phospholipid-cholesterol-apolipoprotein complexes generated with apo A-I, apo A-I-CNBr fragments, apo A-II and apo A-IV for cholesterol esterification by the enzyme lecithin-cholesterol acyltransferase (LCAT). The kinetic parameters determined with the different complexes as substrates, showed that the complexes containing apo A-I and apo A-IV were about 40-times more efficient than those generated with the apo A-I fragments. In this system, the substrates containing apo A-II had the lowest efficiency. In spite of the differences in the kinetic parameters observed with the various apolipoprotein-lipid complexes, the cholesterol inserted in the complexes was esterified for more than 90% after 24 h in all systems studied. Based upon the results of the kinetic experiments, we followed the transformation of the discoidal complexes into spherical particles, due to the formation of a cholesteryl esters core, in the presence of low-density lipoproteins as an external source of cholesterol. We observed the formation of spherical particles by electron microscopy, after incubation of the discoidal complexes with LCAT for 24 h. The average percentage of cholesteryl esters in the converted particles was around 60% of the total cholesterol, varying between 40% for the apo A-I-CNBr-1-DPPC-cholesterol complex and up to 86% for the apo A-I-DPPC-cholesterol complex. The secondary structure of protein in the complexes was not significantly modified. However, the phospholipid phase transition disappeared, together with the parallel orientation of the phospholipid acyl chains with the helical segments of the apolipoproteins, as the phospholipids are organized in a monolayer at the surface of the spheres. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailA sensitivity study of the role of continental area and location on Paleozoic climate
Hauglustaine, Didier A.; Gérard, Jean-Claude ULg

in Global and Planetary Change (1992), 97

Detailed reference viewed: 5 (1 ULg)
Peer Reviewed
See detailLe bâtiment solaire passif de la Fondation Universitaire Luxembourgeoise à Arlon
Andre, Philippe ULg; Nicolas, Jacques ULg; Boreux, Jean-Jacques ULg et al

in Chaleur et climats (1992), (635), 2-8

Description des différentes technologies solaires passives: systèmes à gain direct, murs de masse et serres, mises en oeuvre lors de l'extension de la FUL. Présentation du bilan des performances de ca ... [more ▼]

Description des différentes technologies solaires passives: systèmes à gain direct, murs de masse et serres, mises en oeuvre lors de l'extension de la FUL. Présentation du bilan des performances de ca bâtiment basé sur deux années complètes de mesures intensives [less ▲]

Detailed reference viewed: 65 (5 ULg)
Full Text
Peer Reviewed
See detailIdentification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin.
Castronovo, Vincenzo ULg; Luyten, F.; van den Brule, F. et al

in Archives of Biochemistry & Biophysics (1992), 297(1), 132-8

The carbohydrate moieties present on laminin play a crucial role in the multiple biological activities of this basement membrane glycoprotein. We report the identification of a human laminin binding ... [more ▼]

The carbohydrate moieties present on laminin play a crucial role in the multiple biological activities of this basement membrane glycoprotein. We report the identification of a human laminin binding protein with an apparent molecular mass of 14 kDa on sodium dodecyl sulfate-polyacrylamide gels that was found, after purification and amino acid microsequencing, to be identical to the previously described 14-kDa galactoside binding soluble L-14 lectin. We have designated this human laminin binding protein as HLBP14. HLBP14 was purified from human melanoma cells in culture by laminin affinity chromatography and gel electroelution. We demonstrate that HLBP14 binds specifically to the poly-N-acetyllactosamine residues of murine laminin and does not bind to other glycoproteins that do not contain such structures, such as fibronectin. HLBP14 was eluted from a murine laminin column by lactose, N-acetyllactosamine, and galactose but not by other control saccharides, including glucose, fucose, mannose, and melibiose. It did not bind to laminin treated with endo-beta-galactosidase. Lactose also eluted HLBP14 off a human laminin affinity column, implying that human laminin also contains poly-N-acetyllactosamine residues. On immunoblots, polyclonal antibodies raised against HLBP14 recognized HLBP14 as well as 31- and 67-kDa molecules that are also laminin binding proteins, indicating that these proteins share common epitopes. L-14, a dimeric lactose binding lectin, is expressed in a wide variety of tissues. Although the expression of this molecule has been linked to a variety of biological events, the elucidation of its specific functions has been elusive. The observation that HLBP14, a human cancer cell laminin binding protein, is identical to L-14 strongly suggests that the functions attributed to this lectin could be mediated, at least in part, through its ability to interact with the poly-N-acetyllactosamine residues of laminin. HLBP14 could potentially play a role during tumor invasion and metastasis by modulating the interactions between cancer cells and laminin. [less ▲]

Detailed reference viewed: 12 (0 ULg)
See detailLes bactéries lactiques, une aide alimentaire.
Thonart, Philippe ULg; Roblain, D.

in Mellitus Magazine (1992), 3

Detailed reference viewed: 10 (3 ULg)
Peer Reviewed
See detailThree-dimensional architectures of peritoneal endometriosis.
Donnez, Jacques; NISOLLE, Michelle ULg; Casanas-Roux, Françoise

in Fertility and Sterility (1992), 57(5), 980-3

OBJECTIVE: To elucidate some biological characteristics of peritoneal endometriosis. DESIGN: A recently advanced stereographic computer technology was applied for the investigation of the three ... [more ▼]

OBJECTIVE: To elucidate some biological characteristics of peritoneal endometriosis. DESIGN: A recently advanced stereographic computer technology was applied for the investigation of the three-dimensional (3-D) architectures of peritoneal endometriosis. SETTING: University Hospital of Gynecology. PATIENTS: Biopsies were taken from 42 women with peritoneal endometriosis. Twenty-six of them were in the luteal phase. Seventeen of them received Zoladex (ICI, Cambridge, United Kingdom) for 12 weeks before biopsy. RESULTS: Two different main types could be identified according to the presence or absence of ramifications. The apparently multifocal occurrence (in 2-D) of glandular epithelium was not confirmed by the 3-D study that showed that all epithelial glands are interconnected by luminal structures in each peritoneal lesion. Stereometric study suggests a stronger effect of gonadotropin-releasing hormone agonist therapy on the stroma than on the epithelium. CONCLUSIONS: The study evaluated the 3-D architectures of peritoneal endometriosis and identified two principal types of peritoneal endometriosis. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailPour une dramaturgie du Miracle d'Amis et Amille
Henrard, Nadine ULg

in Moyen français (1992), 30

Detailed reference viewed: 11 (1 ULg)
Full Text
See detailLa carrière de marbre rouge de Beauchâteau: aperçu paléontologique, stratigraphique et sédimentologique
Boulvain, Frédéric ULg; Coen-Aubert, M.

in Annales de la Société Géologique de Belgique (1992), 115

Detailed reference viewed: 35 (0 ULg)
Full Text
Peer Reviewed
See detailL'aérosolthérapie : principes d'action et exigences techniques pour des résultats thérapeutiques optimaux
Genicot, Bruno; Mouligneau, Frédéric; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1992), 136

Detailed reference viewed: 28 (3 ULg)
Full Text
Peer Reviewed
See detailDesign, Synthesis and Biological Activity of a Series of Torasemide Derivatives, Potent Blockers of the Na+ 2cl- K+ Co-Transporter: In-Vitro Study
Masereel, B.; Lohrmann, E.; Schynts, M. et al

in Journal of Pharmacy & Pharmacology (1992), 44

Pharmacomodulation of the torasemide molecule, a loop diuretic inhibiting Na+ 2Cl- K+ co-transport in the thick ascending limb of the loop of Henle has been performed in order to obtain new long-acting ... [more ▼]

Pharmacomodulation of the torasemide molecule, a loop diuretic inhibiting Na+ 2Cl- K+ co-transport in the thick ascending limb of the loop of Henle has been performed in order to obtain new long-acting diuretics. The aim of this study was to decrease the metabolism of the drug and to slow down its rate of excretion by increasing its hydrophobicity. The present study describes the synthesis and the inhibitory potency of new torasemide derivatives in the bioassay system of the cortical thick ascending limb of rabbit. A correlation between the lipophilicity (log P') of these substances and their activity as inhibitors of the Na+ Cl- K+ co-transporter was observed. The present design led to compounds more active than torasemide. Structure-activity relationships permit us to propose an interaction model between torasemide derivatives and the Na+ 2Cl- K+ co-transport system of the cortical thick ascending limb. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailDetermination of verapamil and norverapamil in human plasma by liquid chromatography: comparison between a liquid-liquid extraction procedure and an automated liquid-solid extraction method for sample preparation.
Hubert, Philippe ULg; Chiap, Patrice ULg; Ceccato, Attilio ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (1992), 10(10-12), 937-42

A conventional liquid-liquid extraction (LLE) procedure with high-performance liquid chromatography (HPLC) has been developed for the determination of verapamil and its main metabolite, norverapamil, in ... [more ▼]

A conventional liquid-liquid extraction (LLE) procedure with high-performance liquid chromatography (HPLC) has been developed for the determination of verapamil and its main metabolite, norverapamil, in plasma. After addition of the internal standard, plasma samples were basified with phosphate buffer (pH 9.0) and extracted with a mixture of cyclohexane-dichloromethane. After centrifugation, the organic layer was separated and the analytes were extracted back into a 0.1 N sulphuric acid solution containing 2-aminoheptane. An aliquot of this aqueous phase was then injected directly onto the HPLC column. This LLE procedure has been compared with an automated liquid-solid extraction (LSE) method that has been developed in parallel. Good linearity was obtained using both extraction methods. The absolute recoveries for the two analytes were ca 95% with the automated LSE procedure and slightly lower (ca 84%) for the LLE method. The automated method gives better results with respect to detectability and precision, but the LLE procedure is simpler to develop, requires much less expensive equipment, and remains a useful alternative when the number of samples to be analysed is limited. [less ▲]

Detailed reference viewed: 47 (5 ULg)
Peer Reviewed
See detailNudus... infans... A propos de Lucrèce, V, 222-227
Rochette, Bruno ULg

in Etudes Classiques (Namur, Belgium) (1992), 60

Detailed reference viewed: 17 (0 ULg)
See detailParlez-vous francophonais ?
Defays, Jean-Marc ULg

in Tiedonjyvä (1992)

Detailed reference viewed: 5 (2 ULg)
See detailLes facteurs sous-jacents à l'étude et susceptibles d'influencer les options du schéma de structure communal
Collette, Jean-Pierre ULg; Goossens, Marc ULg; Hanocq, Philippe ULg

in Environnement et Société (1992), 9/10

Analyse de certains facteurs "externes" au projet d'aménagement mais exerçant une influence déterminante sur ses orientations : la confrontation des objectifs communaux et régionaux, les contraintes ... [more ▼]

Analyse de certains facteurs "externes" au projet d'aménagement mais exerçant une influence déterminante sur ses orientations : la confrontation des objectifs communaux et régionaux, les contraintes techniques et politiques locales, les groupes de pression divers. [less ▲]

Detailed reference viewed: 33 (3 ULg)
Peer Reviewed
See detailOntogeny of T-Cell Surface Molecules and Receptors in the Thymus
Defresne, Marie-Paule ULg; Humblet, Chantal ULg; Deman, J. et al

in Progress in Histochemistry and Cytochemistry (1992), 26(1-4), 194-200

Detailed reference viewed: 8 (7 ULg)
See detailModelling the interaction of the deep ocean and the shelf and coastal seas
Nihoul, Jacques ULg; Djenidi, Salim ULg

in Journal of Marine Systems (1992), 3(4-5), 307-308

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailModification of the Selected Method for the Determination of Serum Iron. Substitution of Bathophenanthroline by Ferene S
Charlier, Corinne ULg; Plomteux, Guy ULg; Vernet, M. et al

in Annales de Biologie Clinique (1992), 50(3), 191-202

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene ... [more ▼]

The previously selected method (1977) for the measurement of iron in human serum has been modified by the working group on Iron and Iron-Transport Proteins (Societe Francaise de Biologie Clinique). Ferene S is used as the chromogen, it is more sensitive and cheaper than bathophenanthroline. The sample size has been reduced from 2 to 0.5 ml. No interference could be shown with high concentrations of bilirubin, copper or hemoglobin. [less ▲]

Detailed reference viewed: 45 (3 ULg)
Full Text
Peer Reviewed
See detailEchocardiographic Evaluation of Cardiac Morphologic and Functional Variables in Double-Muscled Calves
Amory, Hélène ULg; Kafidi, Nacereddine ULg; Lekeux, Pierre ULg

in American Journal of Veterinary Research (1992), 53(9), 1540-1547

We studied, by means of echocardiography in vivo, the cardiac consequences of the double-muscled character selection in beef cattle. Morphologic and functional echocardiographic variables were regularly ... [more ▼]

We studied, by means of echocardiography in vivo, the cardiac consequences of the double-muscled character selection in beef cattle. Morphologic and functional echocardiographic variables were regularly estimated in 17 Friesian and 8 Belgian White and Blue calves during their growth. A total of 50 and 44 sets of data were collected in each group, respectively. Recordings were obtained, using 2-dimensional and M-mode echocardiography, and included measurements in long- and short-axis views of the heart. Most of the diastolic measurements of the left ventricle were not significantly different between breeds when normalized for body weight. To the contrary, systolic measurements of left ventricular wall thickness and dimensions were significantly (P less than or equal to 0.001) lower and greater, respectively, in Belgian White and Blue calves than in Friesian calves. This was interpreted as a result of significantly (P less than or equal to 0.001) lower left ventricular systolic functional indices in Belgian White and Blue than in Friesian calves. Echocardiographic evidence that the double-muscled selection in cattle induces alteration in morphologic variables of left ventricle was not found. However, results indicate that indices of left ventricular systolic function are lower in double-muscled calves than in calves with standard conformation. [less ▲]

Detailed reference viewed: 21 (5 ULg)
Peer Reviewed
See detailAlteration of fetal development and hormonal status after dam treatment with anti-insulin like growth factor-I monoclonal antibodies in rat.
Renaville, Robert ULg; Devolder, Anne; Sneyers, Myriam et al

in Journal of Endocrinological Investigation (1992), 15(suppl 4), 85

Detailed reference viewed: 2 (0 ULg)
Full Text
Peer Reviewed
See detailVariation in Productive Efficiency in French Workers’ Cooperatives
Defourny, Jacques ULg; Lovell, C.A. Knox; N'gbo, Aké G.M.

in Journal of Productivity Analysis (1992), 3(1-2), 99-113

In this study, we explore the distribution of productive efficiency among workers’ cooperatives operating in each of four sectors of French manufacturing. We use stochastic frontier panel data techniques ... [more ▼]

In this study, we explore the distribution of productive efficiency among workers’ cooperatives operating in each of four sectors of French manufacturing. We use stochastic frontier panel data techniques to estimate production relationships in each sector, and to decompose output variation into input variation, variation in the effects of two indicators of the degree of worker participation in management, variation in productive efficiency, and an unexplained residual. In all four sectors we find that conventionally measured capital and labor inputs make a significant contribution to productivity. In only one sector do participation indicators contribute significantly. Variation in productive efficiency contributes significantly in all four sectors. [less ▲]

Detailed reference viewed: 25 (6 ULg)
Peer Reviewed
See detailEchelles d'auto-évaluation de la dépression et de l'anxiété
Crasson, Marion ULg

in Psychologie Médicale (1992), 24(11), 1216-1220

Différents types d'échelle d'évaluation se sont développées depuis l'avènement des psychotropes dans les années 50. La passation de certaines d'entre elles, particulièrement les échelles d'auto-évaluation ... [more ▼]

Différents types d'échelle d'évaluation se sont développées depuis l'avènement des psychotropes dans les années 50. La passation de certaines d'entre elles, particulièrement les échelles d'auto-évaluation, peut se réaliser facilement via des systèmes informatisés. Nous présenterons deux de ces échelles, pour lesquelles nous disposons de données normatives et qui sont fréquemment utilisées dans notre laboratoire: l'échelle de dépression de Plutchik et van Praag (PVP) et l'échelle d'anxiété Etat-Trait de Spielberger et coll. (STAI). [less ▲]

Detailed reference viewed: 217 (7 ULg)
Peer Reviewed
See detailAmino acids for the measurement of protein synthesis in vivo by PET.
Vaalburg, W.; Coenen, H. H.; Crouzel, C. et al

in International Journal of Radiation Applications and Instrumentation. Part B : Nuclear Medicine and Biology (1992), 19(2), 227-37

In principle, PET in combination with amino acids labelled with positron-emitting radionuclides and kinetic metabolic models, can quantify local protein synthesis rates in tissue in vivo. These PET ... [more ▼]

In principle, PET in combination with amino acids labelled with positron-emitting radionuclides and kinetic metabolic models, can quantify local protein synthesis rates in tissue in vivo. These PET measurements have clinical potential in, for example, oncology, neurology and psychiatry. An optimal positron-emitting amino acid for the measurement of PSR has a high protein incorporation, can easily be prepared by automated equipment and has minimal non-protein radioactive metabolites. Presently L-[methyl-11C]methionine, L-[1-11C]leucine, L-[1-11C]tyrosine, L-[1-11C]phenylalanine, L-[1-11C]methionine and L-[2-18F]fluorotyrosine are under evaluation in normal volunteers and/or in patients. Several other amino acids are suggested. No comparison of the clinical usefulness of the different amino acids in man is yet available. Because of the longer half life of 18F compared to 11C, [18F]fluoro amino acids may have advantages over [11C]amino acids for the investigation of tissue with relative slow protein synthesis, such as brain, and for application in institutions with an off site, but nearby cyclotron. The half life of [13N]amino acids is considered to be too short for flexible clinical application. As yet no metabolic compartmental model has been investigated for [13N]amino acids. For routine application reliable preparation of the radiopharmaceutical is essential. Of all the amino acids under evaluation, a reliable, high yield, easy to automate production procedure is available for L-[methyl-11C]methionine only. It is however unlikely that this tracer can accurately measure PSR because of its non-protein metabolism. For the other amino acids the main problems in production are associated with complex multistep syntheses and/or low radiochemical yields, complex purification methods and the need to isolate the L-enantiomer. The kinetic metabolic models under investigation, consist of 4 or 5 compartments depending on the necessity to compensate for labelled metabolites. The metabolic profile of the amino acids is mainly extracted from animal experiments. Because of the number and amount of labelled metabolites in plasma, [11C]carboxylic labelled amino acids are preferred to amino acids with carbon-11 in another position. As yet no recommendation can be given on the optimal labelled amino acid(s) for PSR measurement in vivo nor on the methods to prepare the amino acids reported for this purpose. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Peer Reviewed
See detailFire resistance of columns in steel frames
Franssen, Jean-Marc ULg; Dotreppe, Jean-Claude ULg

in Fire Safety Journal (1992), 19(2 - 3), 159-175

The standard fire resistance test is not appropriate for predicting the behaviour of steel frames under fire conditions. The simplified theories that have been published in approved national and ... [more ▼]

The standard fire resistance test is not appropriate for predicting the behaviour of steel frames under fire conditions. The simplified theories that have been published in approved national and international documents apply to some restricted particular cases of single elements (beams, columns). In most practical circumstances beams and columns are subjected to a combination of axial forces and bending moments and have variable restraint and displacement conditions at their ends. The problem is particularly complicated for columns. For this type of situation advanced computer programs can at the present time provide a satisfactory method for the determination of the fire resistance. This paper illustrates the preceding comments by evaluating the fire endurance of an unbraced steel frame with two loading conditions. [less ▲]

Detailed reference viewed: 21 (1 ULg)
See detailLe site et la fouille
Tunca, Önhan ULg

in Akkadica (1992), 79-80

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailEffect of digital nerve stimuli on responses to electrical or magnetic stimulation of the human brain.
MAERTENS DE NOORDHOUT, Alain ULg; Rothwell, J. C.; Day, B. L. et al

in Journal of Physiology (1992), 447

1. Reflexes were elicited in the first dorsal interosseous muscle of seven normal subjects by electrical stimulation of the digital nerves of the index finger at 3 times perceptual threshold while ... [more ▼]

1. Reflexes were elicited in the first dorsal interosseous muscle of seven normal subjects by electrical stimulation of the digital nerves of the index finger at 3 times perceptual threshold while subjects maintained a constant voluntary contraction of the muscle. The average response in the surface-rectified electromyogram (EMG) consisted of an early inhibitory (I1) component followed by a later excitation (E2). 2. Low intensity anodal electrical or magnetic scalp stimuli were given over the motor cortex in order to elicit muscle responses within the period of the I1 and E2 reflex components. 3. Compared with control responses elicited in the absence of digital nerve stimulation, responses to electrical cortex stimulation were suppressed in the I1 period and facilitated during the E2 period of the reflex. In contrast, responses evoked by magnetic stimulation were suppressed during I1 and also for the first 10 ms or so of the E2 response. Magnetically evoked responses were facilitated during the later part of the E2 reflex. 4. Similar effects were seen when the probability of firing of single motor units was studied. 5. In three subjects, small taps were given to the abducted index finger in order to stretch the first dorsal interosseous muscle and evoke reflexes which were of comparable size to the E2 reflex evoked by digital nerve stimulation. In contrast to the experiments in which digital nerve stimuli were given, responses evoked by magnetic stimulation over motor cortex were facilitated at all times during the course of the reflex evoked when the muscle was stretched. 6. We conclude that single electrical stimuli applied to the digital nerves can reduce for a short period the excitability of motor cortex to magnetic stimulation. This occurs at a time when the same stimulus is evoking an excitatory (E2) reflex in the average surface-rectified EMG. [less ▲]

Detailed reference viewed: 10 (3 ULg)
Full Text
See detailCaractéristiques écohydrodynamiques de la Baie Sud de la Mer du Nord en régime d'été
Hecq, Jean-Henri ULg; Mingelbier, Marc; Goffart, Anne ULg et al

in Bulletin de la Société Royale des Sciences de Liège (1992), 61(1-2), 79-97

See pdf file in attachment

Detailed reference viewed: 9 (3 ULg)
Peer Reviewed
See detailComparative Study of Tilidine-Naloxone and Pentazocine in Knee and Hip Osteoarthritis
Van Cauwenberge, Henry ULg; Ruhwiedel, M.; Albert, Adelin ULg et al

in International Journal of Clinical Pharmacology Research (1992), 12(1), 1-9

Fifty patients, twenty-five suffering from severe knee osteoarthritis and twenty-five from acute hip osteoarthritis, received pentazocine or a new preparation of tilidine-naloxone for a period of 2 weeks ... [more ▼]

Fifty patients, twenty-five suffering from severe knee osteoarthritis and twenty-five from acute hip osteoarthritis, received pentazocine or a new preparation of tilidine-naloxone for a period of 2 weeks, in a double-blind study. The two drugs were found to have the same efficacy and tolerance in both diseases with a minor but not statistically significant superiority for tilidine-naloxone. Similar quantities of drugs were taken over the study period, while patients were allowed to take as many as 8 capsules per day to relieve pain. There were quite equivalent side-effects and no marked changes in laboratory tests. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailTHE TRIPLET-STATES OF ALBR
BREDOHL, Harald; DANGUY, P.; DUBOIS, Iwan et al

in Journal of Molecular Spectroscopy (1992), 151(1), 178-183

Twenty bands of the a3Πr-X1Σ+ transition of AlBr have been rotationally analyzed involving v′ from 0 to 10 and v″ from 0 to 8. The Π1 component is perturbed in the v = 0 and 1 vibrational levels. A new ... [more ▼]

Twenty bands of the a3Πr-X1Σ+ transition of AlBr have been rotationally analyzed involving v′ from 0 to 10 and v″ from 0 to 8. The Π1 component is perturbed in the v = 0 and 1 vibrational levels. A new system has been observed for the first time; it is formed of 26 bands and is interpreted as the b3Σ+-X1Σ+ transition. [less ▲]

Detailed reference viewed: 10 (4 ULg)
Full Text
Peer Reviewed
See detailBovine Vectocardiography: A Comparative Study Relative to the Validity of Four Tridimensional Lead Systems
Amory, Hélène ULg; Rollin, Frédéric ULg; Genicot, B. et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1992), 39(6), 453-469

For spatial vectocardiography to become applicable for cardiac investigation in cattle, it was necessary to develop a reliable standardized electrocardiographic lead system in this species. In this study ... [more ▼]

For spatial vectocardiography to become applicable for cardiac investigation in cattle, it was necessary to develop a reliable standardized electrocardiographic lead system in this species. In this study, four tridimensional lead systems, initially developed in horses, were compared when applied in calves. Fifty seven electrocardiograms were collected. The between-subject variability of the magnitude and angles of the tridimensional P, QRS and T modal vectors obtained by use of each lead system was compared. Reproducibility of vectrocardiographic measurements was analyzed by comparing results obtained in 10 calves within a one day interval. The Holmes semi-orthogonal lead system, giving the lowest between-subject variability and the highest between-day reproducibility, appeared to be the most reliable lead system in order to apply vectocardiography in the bovine species. [less ▲]

Detailed reference viewed: 21 (5 ULg)
Full Text
Peer Reviewed
See detailSkinner, mentalismo y cognitivismo
Richelle, Marc ULg

in Anuario de Psicologia (1992), 52(1), 3-15

This paper discusses Skinner's antimentalim related to his radical behaviourism - oppposed to methological behaviourism - and secondly related to the recent evolution towards the cognitivist approach. We ... [more ▼]

This paper discusses Skinner's antimentalim related to his radical behaviourism - oppposed to methological behaviourism - and secondly related to the recent evolution towards the cognitivist approach. We can distinguish different versions in such approach which differ in their methodological, epistemological, ethical and practical contents. References to Skinner's latest writings illustrate his position to these ways of cognitivism. [less ▲]

Detailed reference viewed: 456 (1 ULg)
Peer Reviewed
See detailPHYLOGENETIC STUDY OF CYANOBACTERIA ON THE BASIS OF 16S RIBOSOMAL-RNA SEQUENCES
Nelissen, Bart; Wilmotte, Annick ULg; De Baere, Raymond et al

in Belgian Journal of Botany (1992), 125

In this study, the 16S rRNA sequences of five filamentous cyanobacteria (Cyanophyceae) have been determined. These sequences were used to construct, by a distance matrix method, a tree topology to depict ... [more ▼]

In this study, the 16S rRNA sequences of five filamentous cyanobacteria (Cyanophyceae) have been determined. These sequences were used to construct, by a distance matrix method, a tree topology to depict the phylogenetic relationships among cyanobacteria. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailLa politique québécoise d'alphabétisation
Martiniello, Marco ULg

in Hommes & Migrations (1992), 1151-1152

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailImportance et dynamique du complexe parasitaire du cotonnier dans la région de Gandajika au Zaïre
Delhove, G.; Mergeai, Guy ULg; Mulamba, K.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), (35), 379-387

Full Text
Peer Reviewed
See detailTranscriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factor
Voz, Marianne ULg; Peers, Bernard ULg; Wiedig, Murielle J et al

in Molecular & Cellular Biology (1992), 12(9), 3991-7

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding ... [more ▼]

Human placental lactogen B (hCS-B) promoter activity is strongly stimulated by triiodothyronine (T3) in pituitary GC cells through interaction between the thyroid receptor and a thyroid receptor-binding element (TBE) spanning coordinates -67 to -41. This TBE is adjacent to the binding site for pituitary factor GHF1 (-95 to -68) which seems necessary for T3 stimulation of hCS-B promoter activity (M. L. Voz, B. Peers, A. Belayew, and J. A. Martial, J. Biol. Chem. 266:13397-13404, 1991). We here demonstrate actual synergy between the thyroid receptor and GHF1. Indeed, in placental JEG-3 cells devoid of factor GHF1, hCS promoter activity is barely stimulated by T3, while a strong response is observed in pituitary GC cells. In the latter, furthermore, neither the TBE nor the GHF1-binding site alone is sufficient to render the thymidine kinase promoter responsive to T3, while in combination they promote strong T3 stimulation. Close proximity between these sites is required for optimal synergy: T3 stimulation globally decreases with increased spacing. Furthermore, synergy occurs not only with a GHF1-binding site but also with all other factor recognition sequences tested (Sp1, NF1, CP1, Oct1, and CACCC boxes) and even with two other copies of the TBE. Nor is it specific to hCS TBE, since the palindromic sequence TCAGGTCA TGACCTGA (TREpal) also exhibits cooperativity. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Full Text
See detailA quasi-Newton algorithm for first-odrer saddle-point location
Culot, Patrick; Dive, Georges ULg; Nguyen, Van Hen et al

in Theoretica Chimica Acta (1992), 82

A new algorithm for the location of a transition-state structure on an energy hypersurface is proposed. The method is compared to three other quasi-Newton step calculations available in literature ... [more ▼]

A new algorithm for the location of a transition-state structure on an energy hypersurface is proposed. The method is compared to three other quasi-Newton step calculations available in literature. Numerical results derived from several examples are compared to those obtained by the two algorithms implemented in the Gaussian package. [less ▲]

Detailed reference viewed: 24 (6 ULg)
Peer Reviewed
See detailMiospores et Foraminifères du Famennien des Massifs des Mdakra et du Khatouat (Maroc).
Vachard, D; Loboziak, S; Fadli, D et al

in Sciences Géologiques : Mémoire (1992), 83

Detailed reference viewed: 2 (1 ULg)
Peer Reviewed
See detailPlant greening - Biogenesis of photosynthetic apparatus in bean leaves irradiated shortly after germination
Schoefs, B.; Bertrand, M.; Franck, Fabrice ULg

in Photosynthetica (1992), 27(4), 497-504

Formation of the photosynthetic apparatus in dark-grown 2-day-old bean (Phaseolus vulgaris L.) leaves was studied. The photosystem 2 (PS 2) reaction centres started functioning 1 h after the beginning of ... [more ▼]

Formation of the photosynthetic apparatus in dark-grown 2-day-old bean (Phaseolus vulgaris L.) leaves was studied. The photosystem 2 (PS 2) reaction centres started functioning 1 h after the beginning of irradiation. Electron transport between the two photosystems started after 4 h of irradiation. The PS 2 units were able to transfer the excitation energy to each other after 10 h of greening. The photosynthetic activity appeared a long time before the typical 77 K fluorescence bands of green leaves appeared. [less ▲]

Detailed reference viewed: 15 (1 ULg)
Peer Reviewed
See detailDawsonites magnus sp. nov., une plante nouvelle du Dévonien inférieur d'Ensival (Belgique).
Gerrienne, Philippe ULg

in Comptes Rendus de l'Académie des Sciences. Série II. Mécanique, Physique, Chimie, Sciences de l'Univers, Sciences de la Terre (1992), 315

Detailed reference viewed: 1 (0 ULg)
Peer Reviewed
See detailGrowth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats.
Reiter, E.; Bonnet, Pierre ULg; Sente, B. et al

in Molecular & Cellular Endocrinology (1992), 88(1-3), 77-87

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented ... [more ▼]

In this study we investigated the involvement of several different pituitary hormones on rat prostate development. 22-day-old Wistar rats, hypophysectomized (hypox) at 19 days of age were supplemented with highly purified human prolactin (hPRL), human luteinizing hormone (hLH), porcine follicle-stimulating hormone (pFSH), and bovine growth hormone (bGH) or with saline. Quantitative analysis of RNAs shows that treatment with either PRL or GH increases significantly steady-state mRNAs levels of the following genes in the prostate: androgen receptor (AR) (respectively 3.5- and 4.8-fold above hypox controls), IGF-I (5- and 2.7-fold), and IGF-I receptor (2.9- and 2.3-fold). LH and FSH, by contrast, have negative effects on these parameters. To test whether the enhancing effect of PRL and GH on AR-mRNA abundance was followed by increased content in the protein itself, binding assays were performed with the androgen agonist [3H]R1881 (131 and 153 fmol/mg protein while hypox controls contained 110 fmol/mg protein). In addition to the well-documented presence of prolactin receptors in prostatic tissues, we have further demonstrated, by means of nuclease S1 protection assays plus dot- and Northern-blot analyses, that a GH receptor mRNA is produced in the immature rat prostate. Moreover, we observed not only strong lactogenic but also purely somatogenic binding to be occurring in the immature prostates. Finally, we have studied IGF-I mRNA content in separated epithelial/stromal cell fractions and have concluded that IGF-I expression is principally located in the prostatic stroma. Taken together, these results suggest that PRL and GH are involved in regulating AR synthesis, at least partially by direct action on the organ. In this context IGF-I appears as a paracrine factor playing a role in epithelium/stroma interactions during prostatic development. [less ▲]

Detailed reference viewed: 29 (1 ULg)
Full Text
Peer Reviewed
See detailExpression of members of the putative olfactory receptor gene family in mammalian germ cells.
Parmentier, M.; Libert, F.; Schurmans, Stéphane ULg et al

in Nature (1992), 355

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the ... [more ▼]

A series of genomic and complementary DNA clones encoding new putative members of G protein-coupled receptors were isolated using homology cloning and low-stringency polymerase chain reaction. Among the unidentified receptors ('orphan receptors'), a human genomic clone (HGMP07) was characterized by the presence of its transcripts in the testis and by its belonging to a large subfamily of genes sharing extensive sequence similarities. Sequence comparison demonstrated that this gene subfamily is the human counterpart of the putative rat olfactory receptors cloned recently. Another 48 members of the family were cloned. Northern blotting further demonstrated the presence of olfactory receptor transcripts in germ cells. Our finding suggests that a common receptor gene family encodes olfactory receptors and sperm cell receptors that could be involved in chemotaxis during fertilization [less ▲]

Detailed reference viewed: 21 (5 ULg)
Peer Reviewed
See detailHuman placental growth hormone
Frankenne, Francis; Evain-Brion, Danielle; Alsat, Eliane et al

in Anales Espanoles de Pediatria (1992), 36(50), 77-80

Detailed reference viewed: 12 (3 ULg)
Peer Reviewed
See detailIdentification of patients at high risk for recurrence of sustained ventricular tachycardia after healing of acute myocardial infarction.
Rodriguez, L M; Oyarzun, R; Smeets, J et al

in American Journal of Cardiology (1992), 69(5), 462-4

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular ... [more ▼]

A prognostic index for nonfatal recurrences of ventricular tachycardia (VT) was developed using a retrospective analysis of a group of 206 patients with sustained monomorphic VT or ventricular fibrillation (VF) after healing of acute myocardial infarction. 74 patients (36%) (64 with VT and 10 with VF) had recurrences of sustained monomorphic VT during 3.4 +/- 9 years of follow-up. Three clinical variables were selected and weighted by stepwise logistic discriminant analysis of the study group. They were coded as follows: interval of myocardial infarction to arrhythmia (less than 2 months = 1; 2 to 6 months = 2; greater than 6 months = 3), drug therapy with or without sotalol (with = 1, without = 2), and VT or VF as the presenting arrhythmia (VT = 1, VF = 2). The prognostic index was: 3.41 - (0.56 x interval) - (1.94 x therapy) + (0.86 x arrhythmia). This index was validated prospectively in a test group of 158 consecutive patients with VT or VF after healing of acute myocardial infarction. Patients were allocated into different classes with decreasing prognostic index values associated with increasing risk for recurrences of VT. In the test group, 27 of 158 (17%) patients (22 with VT and 5 with VF) had recurrences of VT (follow-up of 2 +/- 2 years). Two risk classes of patients were identified: high risk for recurrences of VT (61%) corresponding to patients with a negative index; and low risk (4%) consisting of those with a positive index. Thus, using O as the cutoff point, the sensitivity, specificity, and positive and negative predictive values were 81, 89, 62 and 96%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲]

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailCompte-rendu de l'ouvrage de Serge Paugam: La disqualification sociale
Robert, Jocelyne ULg

in Revue de l'Institut de Sociologie (1992)

Detailed reference viewed: 22 (0 ULg)
Peer Reviewed
See detailAntagonistes calciques et calcithérapie : incompatibilité ?
Mottard, L; Lecart, MP; Reginster, Jean-Yves ULg

in Actualité Médicale Belge (1992), 335

Detailed reference viewed: 1 (1 ULg)
Peer Reviewed
See detailDe l'histoire de l'art aux sciences de l'image et de l'objet
Duchesne, Jean-Patrick ULg

in Art&Fact (1992), 11

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailLa répartition des noms propres dans les œuvres érotiques d’Ovide
Purnelle, Gérald ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1992)

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailDensitometric Evaluation of Spiraeoside after Derivatization in Flowers of Filipendula Ulmaria (L.) Maxim
Poukens-Renwart, P.; Tits, Monique ULg; Wauters, Jean-Noël ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (1992), 10(10-12, Oct-Dec), 1085-8

Spiraeoside (quercetin-4'-glucoside) is the major and most caharacteristic flavonoid of Filipendula ulmaria flowers and is not found in the leaves and stems. This paper describes a quantification of ... [more ▼]

Spiraeoside (quercetin-4'-glucoside) is the major and most caharacteristic flavonoid of Filipendula ulmaria flowers and is not found in the leaves and stems. This paper describes a quantification of spiraeoside by HPTLC densitometry after derivatization with diphenylboric acid -2-aminoester. The fluorescence of this flavonoid was measured at 330 nm. the spiraeoside content in batches of Filipendula ulmaria flowers ranged from 3 to 4.3 %. It is of note that these results are similar to those published elsewhere after HPLC analysis of other batches. [less ▲]

Detailed reference viewed: 59 (1 ULg)
Peer Reviewed
See detailThe faint young sun climatic paradox: A simulation with an interactive seasonal climate-sea ice model
Gérard, Jean-Claude ULg; Hauglustaine, Didier A.; François, Louis ULg

in Global and Planetary Change (1992), 97(3), 133-150

A seasonal one-and-a-half-dimensional (1 1/2-D) energy-balance climate model including a detailed sea ice calculation and an interactive albedo formulation has been developed and is used to investigate ... [more ▼]

A seasonal one-and-a-half-dimensional (1 1/2-D) energy-balance climate model including a detailed sea ice calculation and an interactive albedo formulation has been developed and is used to investigate the faint young sun climatic paradox. This model is shown to reproduce the present climate and sea ice observations. In spite of its greater complexity, its behavior is globally similar to simple energy-balance models with highly parameterized ice-albedo feedback used in previous studies of this question. It is found that when the solar luminosity drops by more than about 5% below its present value, the ice albedo feedback causes a global irreversible glaciation. Several sensitivity experiments show that the value of the critical solar constant and associated global surface temperature are only little sensitive to the set of model parameters describing the ice and snow albedo and meridional heat transport. In contrast, the absence or polar location of the continental mass introduce a nearly 10% decrease of the critical luminosity. The minimum level of atmospheric CO2 needed to prevent a global glaciation through enhanced greenhouse warming is calculated as a function of the solar luminosity. A 30% drop in solar output requires a 2 x 10(4)-fold increase in atmospheric CO2, an unacceptably large value. However, in the absence of continents, a carbon dioxide partial pressure of 2000 times the present level is found to be sufficient to stabilize the climate. The effects of a reduced continental area, paleogeographic changes and higher CO2 greenhouse effect combine to ensure a larger stability of the non-frozen configuration. Their cumulated and interactive effects may be able to solve the young sun paradox. [less ▲]

Detailed reference viewed: 47 (9 ULg)
Full Text
See detailMicroflore des monticules frasniens "F2j" de Belgique
Mamet, B.; Boulvain, Frédéric ULg

in Revue de micropaléontologie (1992), 35(4), 283-302

Detailed reference viewed: 11 (3 ULg)
Peer Reviewed
See detailDétermination en mode maillé du champ d’intervisibilité dans un modèle numérique de terrain
Donnay, Jean-Paul ULg

in Cartographica (1992), 29(3-4), 75-82

Detailed reference viewed: 23 (4 ULg)
Peer Reviewed
See detailInfluence of laminin or fibroblasts upon colony formation in the mouse by B16 melanoma cell spheroids: a morphometric analysis.
Coucke, P.; de Leval, Laurence ULg; Leyh, P. et al

in In Vivo (Athens, Greece) (1992), 6(2), 119-24

By microscopical observation and using an original morphometric method, we analyzed on histological sections the rate of lung colony formation after the intravenous injection into the mouse of B16 ... [more ▼]

By microscopical observation and using an original morphometric method, we analyzed on histological sections the rate of lung colony formation after the intravenous injection into the mouse of B16 melanoma cells previously cultivated in vitro as aggregates. After the injection of B16 pure spheroids, superficial lung colonies were more numerous than internal lung colonies. After the injection of mixed spheroids (B16 + 3T3 fibroblasts), the size of colony sections was increased. Addition of laminin to pure or mixed spheroids decreased the size of colony sections but increased the number of internal lung colonies. [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailCalcitonin and bone diseases
Reginster, Jean-Yves ULg

in Lancet (1992), 339

Detailed reference viewed: 1 (1 ULg)
Full Text
Peer Reviewed
See detailCharacterization of regulatory functions of the varicella-zoster virus gene-63-encoded protein
Jackers, Pascale ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Journal of Virology (1992), 66(6), 3899-3903

Varicella-zoster virus (VZV) gene 63 encodes a protein (IE63) with a predicted molecular mass of 30.5 kDa which has amino acid similarities to the immediate-early (IE) protein 22 (ICP22) of herpes simplex ... [more ▼]

Varicella-zoster virus (VZV) gene 63 encodes a protein (IE63) with a predicted molecular mass of 30.5 kDa which has amino acid similarities to the immediate-early (IE) protein 22 (ICP22) of herpes simplex virus type 1. ICP22 is a polypeptide synthesized in herpes simplex virus type 1-infected cells, and as is the case for its VZV counterpart, its regulatory functions are unknown. On the basis of the VZV DNA sequence, it has been shown that IE63 exhibits hydrophilic and acidic properties, suggesting that this protein could play a regulatory role during the infectious cycle. We report in this article cotransfection experiments which demonstrate that the VZV gene 63 protein strongly represses, in a dose-dependent manner, the expression of VZV gene 62. On the other hand, transient expression of the VZV gene 63 protein can promote activation of the thymidine kinase gene but cannot affect the expression of the genes encoding glycoproteins I and II. The results of transient expression experiments strongly suggest that the VZV gene 63 protein could play a pivotal role in the repression of IE gene expression as well as in the activation of early gene expression [less ▲]

Detailed reference viewed: 47 (20 ULg)