References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 37901 to 38000 of 54793     375 376 377 378 379 380 381 382 383 384 385     Allozyme variation supports an autopolyploid origin and high genetic diversity in tetraploid cranberry, Vaccinium oxycoccos (Ericaceae)Mahy, Grégory ; Bruederle, L. P.; Connors, B. et alin American Journal of Botany (2000), 87Detailed reference viewed: 14 (0 ULg) Systemic Induction Of Phytoalexins In Cucumber In Response To Treatments With Fluorescent PseudomonadsOngena, MARC ; Daayf, F.; Jacques, Philippe et alin Plant Pathology (2000), 49(4), The Pseudomonas putida isolate BTP1 and its sid2 mutant M3 were recently reported to protect cucumber against Pythium aphanidermatum root rot. This protection was mainly associated with an accumulation of ... [more ▼]The Pseudomonas putida isolate BTP1 and its sid2 mutant M3 were recently reported to protect cucumber against Pythium aphanidermatum root rot. This protection was mainly associated with an accumulation of antifungal phenolics in the treated roots. In this study, analyses of root extracts from split-root experiments showed that these phytoalexins were produced systemically. Indeed, several antifungal molecules accumulated similarly in both treated and nontreated root parts of plants protected against P. aphanidermatum with BTP1 or M3. In addition, analyses of leaf samples also revealed increased amounts of fungitoxic molecules in PGPR-treated plants, although the nature of these molecules appeared to be different from those detected in roots. The antifungal compounds isolated both from roots and leaves were mainly detected in acid-hydrolyzed extracts containing aglycones. These results suggest that PGPR can elicit phytoalexins systemically in cucumber and that the overall defence response is not based on a single phytoalexin but is chemically complex and organ-specific. [less ▲]Detailed reference viewed: 37 (4 ULg) Table of Ap and Am Stars in order of Variable-star Names IIRenson, Pierre in A Peculiar Newsletter (2000), 33Detailed reference viewed: 17 (3 ULg) Critical points and reaction paths characterization on a potential energy hypersurfaceRamquet, Marie-Noëlle; Dive, Georges ; Dehareng, Dominique in Journal of Chemical Physics (2000), 112(11), 4923-4934Most of the time, the definitions of minima, saddle points or more generally order p (p=0,...,n) critical points, do not mention the possibility of having zero Hessian eigenvalues. This feature reflects ... [more ▼]Most of the time, the definitions of minima, saddle points or more generally order p (p=0,...,n) critical points, do not mention the possibility of having zero Hessian eigenvalues. This feature reflects some flatness of the potential energy hypersurface in a special eigendirection which is not often taken into account. Thus, the definitions of critical points are revisited in a more general framework within this context. The concepts of bifurcation points, branching points, and valley ridge inflection points are investigated. New definitions based on the mathematical formulation of the reaction path are given and some of their properties are outlined. (C) 2000 American Institute of Physics. [S0021-9606(00)01110-7]. [less ▲]Detailed reference viewed: 30 (0 ULg) Effects of cold and warm ischemia on the mitochondrial oxidative phosphorylation of swine lung.Willet, Katty; Detry, Olivier ; Lambermont, Bernard et alin Transplantation (2000), 69(4), 582-588BACKGROUND: The aim of the study was to investigate the consequence of warm and cold ischemia on lung mitochondria in order to define bioenergetic limits within lung could be suitable for pulmonary ... [more ▼]BACKGROUND: The aim of the study was to investigate the consequence of warm and cold ischemia on lung mitochondria in order to define bioenergetic limits within lung could be suitable for pulmonary transplantation. METHODS: Twenty-two pigs underwent lung harvesting after lung flush with Euro-Collins solution. Mitochondria were isolated from fresh lungs, from lungs submitted to 24 or 48 hr of cold ischemia, to 30 or 45 min of warm ischemia, and to 30 min of warm ischemia followed by 24 or 48 hr of cold ischemia. Mitochondrial oxidative phosphorylation parameters were determined in isolated mitochondria by in vitro measurement of oxygen consumption. RESULTS: Relative to controls, mitochondria submitted to cold ischemia showed an alteration in the oxidoreductase activities of the respiratory chain but no membrane permeability alteration. After 48 hr of cold ischemia, there was a decrease in the yield of the oxidative phosphorylation. Thirty minutes of warm ischemia did not alter the mitochondrial respiratory parameters. However, lung submitted to 45 min of warm ischemia showed mitochondrial damage as a decrease in the oxidative phosphorylation efficiency and ADP availability but no change in the oxidoreductase activities. Relative to cold ischemia alone, 30 min of warm ischemia preceding cold ischemia promoted no significant change in the respiratory parameters. CONCLUSIONS: On bioenergetic basis, lung submitted to warm ischemia could be suitable for transplantation if the warm ischemia duration does not exceed 30 min. This could be a major concern in lung procurement from non-heart beating donors. [less ▲]Detailed reference viewed: 25 (8 ULg) Eating and Body Representations and Practices in Adolescence. Preliminary Results.D'Amore, Salvatore in European Journal of Clinical Nutrition (2000), 54(4), 9Detailed reference viewed: 14 (4 ULg) Fetal renal artery flow and renal echogenicity in the chronically hypoxic state.Suranyi, Andrea; Streitman, Karoly; Pal, Attila et alin Pediatric Nephrology : Journal of the International Pediatric Nephrology Association (2000), 14(5), 393-399The object of this study was to investigate the fetal renal arterial blood flow in normal and hyperechogenic kidneys during the third trimester of gestation. The pregnancies screened were all chronically ... [more ▼]The object of this study was to investigate the fetal renal arterial blood flow in normal and hyperechogenic kidneys during the third trimester of gestation. The pregnancies screened were all chronically hypoxic. Depending on the etiology of the intrauterine chronic hypoxia, the cases were divided into two study groups. Group I comprised 120 pregnant women with pregnancy-associated hypertension and/or proteinuria. Group II consisted of 87 pregnancies with intrauterine growth retardation. Both study groups included pregnant women from the third trimester. Hyperechogenic renal medullae were detected in 15 out of 120 cases with pregnancy-associated hypertension and/or proteinuria, and in 22 fetuses of the 87 pregnancies involving intrauterine growth retardation. Fetal renal hyperechogenicity appears to be an indicator of fetal arterial circulatory depression, correlated with pathological changes in the resistance index for the fetal renal arteries. The fetal renal arterial blood flow resistance index was significantly lower in hyperechogenic cases. This may also be an in utero indication of subsequent intrauterine and neonatal complications, such as cesarean section because of fetal distress (43%), treatment in a neonatal intensive care unit (51%) or increased perinatal mortality (5.4%, as compared with 0.8-1.0% in the normal population). Detailed ultrasound and Doppler examinations of renal parenchyma and arteries appear to be useful methods in the prenatal diagnosis of reduced renal perfusion and of intrauterine hypoxia to detect possible pathological fetal conditions in utero. [less ▲]Detailed reference viewed: 77 (4 ULg) Particularités de la prise en charge de l'excès pondéral chez l'adolescent : résultats d'une enquête exploratoire et implications pour la pratiqueGrignard, Sophie ; Bourguignon, Jean-Pierre ; Born, Michel et alin Bulletin d'Education du Patient (2000), 19(3), 132-138Detailed reference viewed: 61 (24 ULg) Rythmes du temps: de l'Astronomie à l'HistoireBiémont, Emile in Ciel et Terre (2000), 116(3), 72-81Detailed reference viewed: 17 (1 ULg) Footprint Analysis For Measurements Over A Heterogeneous ForestRannik, U.; Aubinet, Marc ; Kurbanmuradov, O. et alin Boundary-Layer Meteorology (2000), 97(1), Detailed reference viewed: 24 (4 ULg) Lifetimes of metastable state in Sr IIBiémont, Emile ; Lidberg, J.; Mannervik, S. et alin European Physical Journal D -- Atoms, Molecules, Clusters & Optical Physics (2000), 11Detailed reference viewed: 8 (1 ULg) High production of SPARC/osteonectin/BM-40 in mouse metastatic B16 melanoma cell linesKato, Y.; Frankenne, F.; Noël, Agnès et alin Pathology Oncology Research (2000), 6(1), 24-26Abstract Production of SPARC/osteonectin/BM-40 was determined in mouse B16 melanoma clones BL6 and F10 (high metastatic) and F1 (low metastatic). SPARC was produced greater amount in BL6 and F10 than in ... [more ▼]Abstract Production of SPARC/osteonectin/BM-40 was determined in mouse B16 melanoma clones BL6 and F10 (high metastatic) and F1 (low metastatic). SPARC was produced greater amount in BL6 and F10 than in F1 cells, showing a good agreement with their metastatic potentials. Moreover, SPARC production was not influenced by culture pH, even in the acidic conditions (= pH 5.9). Although tumor tissues show often low pH due to excessive amount of acidic metabolites such as lactate, most studies have been done in neutral pH. High SPARC production in the acidic medium, therefore, is thought to be an important potential for tumor invasive behaviour. [less ▲]Detailed reference viewed: 1 (0 ULg) Localization of Nadph-Protochlorophyllide Reductase in Plastids of Barley at Different Greening StagesBarthelemy, X.; Bouvier, G.; Radunz, A. et alin Photosynthesis Research (2000), 64(1), 63-76The localization of protochorophyllide (Pchlide) and of NADPH-protochlorophyllide oxidoreductase (POR, EC 1.6.99.1) within (etio)chloroplasts has been investigated at selected stages of greening of barley ... [more ▼]The localization of protochorophyllide (Pchlide) and of NADPH-protochlorophyllide oxidoreductase (POR, EC 1.6.99.1) within (etio)chloroplasts has been investigated at selected stages of greening of barley seedlings. Pchlide pigment and POR protein contents were evaluated in different plastid membrane fractions by fluorescence spectroscopy and immunoblot analysis using a monospecific polyclonal antibody raised against the purified enzyme. Fluorescence analysis showed the presence of Pchlide in both the envelope and thylakoid membranes. During greening, the Pchlide content, expressed on a total protein basis, decreased in thylakoid membranes, whereas it increased in the envelope membranes. POR proteins were detected mainly in thylakoid membranes at early greening stages. In contrast, the weak amount of POR proteins was associated more specifically with envelope membranes of mature chloroplasts. Whatever the greening stage, thylakoid-bound Pchlide and POR proteins were more abundant in the thylakoid regions which remained unsolubilized after mild Triton treatment used as standard procedure to prepare PS II particles. This suggests the preferential association of Pchlide and POR to the appressed regions of thylakoids. [less ▲]Detailed reference viewed: 7 (0 ULg) Gas Phase Thermal Denaturation of an Oligonucleotide Duplex and Its Complexes with Minor Groove BindersGabelica, Valérie ; Rosu, Frédéric ; Houssier, Claude et alin Rapid Communications in Mass Spectrometry : RCM (2000), 14(6), 464-467Electrospray ionization with in-source collisionally induced dissociation has been used to probe the gas phase stability of an oligonucleotide duplex and its complexes with some minor groove binding drugs ... [more ▼]Electrospray ionization with in-source collisionally induced dissociation has been used to probe the gas phase stability of an oligonucleotide duplex and its complexes with some minor groove binding drugs. On the basis of the arguments developed in detail by Drahos et al. (J. Mass Spectrom. 1999; 34:1373), this type of experiment can also be described as 'thermal denaturation in the gas phase'. We found that the gas phase denaturation curves were very similar to the solution phase denaturation curves determined by the traditional UV spectrophotometric method and, by analogy with the melting temperature T(m) which characterizes the stability in solution, we define a melting voltage V(m) to characterize the stability in the gas phase. A comparison of the T(m) and V(m) relative values suggests that the structure of the complexes is conserved during the electrospray process which transfers the ions from the solution to the gas phase. [less ▲]Detailed reference viewed: 67 (7 ULg) Contribution à la connaissance des Chrysopidae de Belgique : bilan des captures réalisées à Gembloux.Mignon, Jacques ; Bozsik, Andras; Gaspar, Charlesin Notes Fauniques de Gembloux (2000), 41Douze espèces de Chrysopidae furent identifiées: H. elegans, N. flava, N. pallida, Ch. ciliata, Ch. perla, Ch. pallens, D. flavifrons, D. prasina, D. ventralis, T. gracilis, Ch. carnea et C. albolineata ... [more ▼]Douze espèces de Chrysopidae furent identifiées: H. elegans, N. flava, N. pallida, Ch. ciliata, Ch. perla, Ch. pallens, D. flavifrons, D. prasina, D. ventralis, T. gracilis, Ch. carnea et C. albolineata. Une espèce, Tjederina ventralis est nouvelle pour la faune belge. [less ▲]Detailed reference viewed: 58 (9 ULg) La prise en charge de patients Alzheimer au stade débutant : Rôle d'un centre de jourAdam, Stéphane ; Van der Linden, Martial in Rééducation Orthophonique (2000), 201Detailed reference viewed: 192 (13 ULg) Les artisans-producteurs face aux problèmes de conservation.Sindic, Marianne ; Rolland, Sandrinein Dieta (2000), (20), 6-7Detailed reference viewed: 16 (1 ULg) Relative impact of a seagrass bed and its adjacent epilithic algal community in consumer dietsLepoint, Gilles ; Nyssen, Fabienne ; Gobert, Sylvie et alin Marine Biology (2000), 136The aim of this work was to identify and compare, using nitrogen and carbon stable isotope data, the food sources supporting consumer communities in a Mediterranean seagrass bed (Gulf of Calvi, Corsica ... [more ▼]The aim of this work was to identify and compare, using nitrogen and carbon stable isotope data, the food sources supporting consumer communities in a Mediterranean seagrass bed (Gulf of Calvi, Corsica) with those in an adjacent epilithic algal dominated community. Isotopic data for consumers are not significantly different in the two communities. Particulate matter and algal material (seagrass epiflora and dominant epilithic macroalgae) appear to be the main food sources in both communities. Generally, the 13C of animals suggests that the seagrass Posidonia oceanica (L.) Delile represents only a minor component of their diet or of the diet of their prey, but the occurrence of a mixed diet is not excluded. P.oceanica dominates the diet of only of few species, among which holothurians appear as key components in the cycling of seagrass material. [less ▲]Detailed reference viewed: 77 (20 ULg) La cultura política en América Latina: la transición inacabada. Sobre Geraldine Lievesley, Democracy in Latin America. Mobilization, Power and the Search for a New PoliticsVanden Berghe, Kristine in Foro Hispánico (2000), 18Detailed reference viewed: 32 (0 ULg) The Emancipation of Women in Ancient RomeGerkens, Jean-François ; Vigneron, Rogerin Revue Internationale des Droits de l'Antiquité (2000), 47Detailed reference viewed: 248 (1 ULg) Comment utiliser l'hypnose en anesthésieFaymonville, Marie ; Joris, Jean ; Lamy, Maurice in Praticien en Anesthésie Réanimation (Le) (2000), 4(6), 345-348Detailed reference viewed: 226 (8 ULg) Protective Effects Of A Live Attenuated Bovine Leukaemia Virus Vaccine With Deletion In The R3 And G4 GenesReichert, M.; Cantor, Gh.; Willems, Luc et alin Journal of General Virology (2000), 81Detailed reference viewed: 10 (1 ULg) Derived Categories for Functional AnalysisProsmans, Fabienne in Publications of the Research Institute for Mathematical Sciences (2000), 36(1), 19-83We study the homological algebra of the category of locally convex topological vector spaces from the point of view of derived categories.Detailed reference viewed: 40 (18 ULg) Thymic neuroendocrine self-antigens. Role in T-cell development and central T-cell self-toleranceGeenen, Vincent ; Martens, Henri ; Brilot, Fabienne et alin Annals of the New York Academy of Sciences (2000), 917Detailed reference viewed: 17 (1 ULg) Excess atmospheric carbon dioxide transported by rivers into the Scheldt EstuaryAbril, Gwenaël; Etcheber, Henri; Borges, Alberto et alin Comptes Rendus de l'Académie des Sciences de Paris (2000), 330The transport of excess atmospheric CO2 (defined as the fraction of dissolved inorganic carbon (DIC) that can escape as CO2 to the atmosphere due to water-air equilibration), by the five rivers entering ... [more ▼]The transport of excess atmospheric CO2 (defined as the fraction of dissolved inorganic carbon (DIC) that can escape as CO2 to the atmosphere due to water-air equilibration), by the five rivers entering the Scheldt estuary is investigated. Excess CO2 originates from both respiration in the soil and the river and represents 10 % of the DIC and 6 % of the total carbon input into the estuary. The ventilation of this CO2 in the estuary is however a minor contribution (10 %) to the total estuarine emission to the atmosphere, compared to heterotrophic activity and acidification due to nitrification within the estuarine zone. [less ▲]Detailed reference viewed: 39 (2 ULg) Morphological comparison of the buccal apparatus in two bivalve commensal Teleostei : Encheliophis dubius and Onuxodon fowleri (Carapidae, Ophidiiformes)Parmentier, Eric ; Castro-Aguirre, J. L.; Vandewalle, Pierre in Zoomorphology (2000), 120Onuxodon fowleri and Encheliophis dubius are two Carapidae species that live in bivalve hosts and, their diet is made of the same type of prey. The aim of this study is to compare their cephalic ... [more ▼]Onuxodon fowleri and Encheliophis dubius are two Carapidae species that live in bivalve hosts and, their diet is made of the same type of prey. The aim of this study is to compare their cephalic morphology to see whether 1) the head anatomy of both species is related to the constraints of their way of life, and 2) there are difference between these species and commensal carapids that shelter in other invertebrates. The components of their skeletons and muscles are similar, but differ in size and are arranged differently. In O. fowleri, the buccal cavity is smaller than in E. dubius, the jaws (bearing very large anterior teeth) are larger, the quadrato-mandibular joint lies further to the rear, the fibres of muscle bundles A3a, A2a and A2b are more vertical and insert higher on the neurocranium. The buccal system of O. fowleri appears better suited for ingesting food by biting and grasping. That of E. dubius seems better adapted to a feeding mechanism where sucking would have a more important role. The E. dubius head morphology is more similar to the cephalic anatomy of non-bivalve commensal species than to O. fowleri features. Diet constraints may have greater influence than the different host constraints on the head construction. A simulated backward rotation of the posterior part of the E. dubius suspensorium around the posterior joint between the hyomandibular and the neurocranium brings the jaws and the cheeks to coincide with those of O. fowleri. This model could be indicative of how structure modifications and their influences on annex pieces could in part have a role in the biodiversity. [less ▲]Detailed reference viewed: 22 (1 ULg) Simulation of first and second order scattering by rough surfaces with a sound ray formalismEmbrechts, Jean-Jacques in Journal of Sound & Vibration (2000), 229(1)Detailed reference viewed: 20 (2 ULg) Chemical changes and influences of rapeseed antinutritional factors on lamb physiology and performance. 3. Antinutritional factors in plasma and organsMabon, N.; Mandiki, S. N. M.; Derycke, G. et alin Animal Feed Science & Technology (2000), 85(1-2), 111-120The impact of a high level of rapeseed meal in the diet on the concentration of antinutritional factors in plasma and organs was studied in 66 Texel, Suffolk or crossbred lambs. From 1 month of age till ... [more ▼]The impact of a high level of rapeseed meal in the diet on the concentration of antinutritional factors in plasma and organs was studied in 66 Texel, Suffolk or crossbred lambs. From 1 month of age till slaughter (132+/-21 days), they were fed ad libitum with concentrates containing 0% or 25% of rapeseed meal obtained either Samourai or Honk rapeseed varieties. Lambs were weaned at 88+/-8 days of age and 24+/-5 kg live weight. Blood and organ samples were taken fortnightly for the determination of antinutritional factors. In plasma and organs, the thiocyanate concentrations were systematically higher in the Samourai and Honk lots than in the control. After weaning, the SCN- concentration in plasma increased up to 490 mu mol l(-1) in the Samourai lot. The goitrogen 5-vinyl-1,3-oxazolidine-2-thione (5-VOT) was determined in muscle, organs (thyroid, liver, kidney and lung) and biological fluid (plasma). The 5-VOT was present only after the ingestion of rapeseed meal but not to the same extent for the two varieties. The Honk rapeseed meal induced a 5-VOT level significantly (p<0.05) higher in the target organs such as lung and thyroid than Samourai. Very low levels were found in muscle, liver, kidney, plasma and lung. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]Detailed reference viewed: 57 (1 ULg) Impact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.Hustinx, Roland ; Dolin, R. J.; Benard, F. et alin European Journal of Nuclear Medicine (2000), 27(9), 1365-71The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating ... [more ▼]The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating characteristic (FROC) methodology. Thirty-four patients with various abdominal tumors were evaluated (11 men, 23 women, median age 48 years). Whole-body emission scans were performed 68 min (35-102 min) after intravenous injection of 4.3 MBq/kg fluorine-18 fluorodeoxyglucose (FDG). Images were reconstructed using the OS-EM algorithm and corrected for attenuation either using postinjection singles transmission (n=27) or by calculation and body outline (n=7). Total scan duration did not exceed 70 min. Studies were read independently by four observers unaware of any clinical data. The uncorrected (UC) images were systematically read before the attenuation-corrected (AC) images. All studies were given an image quality score ranging from 1 (unreadable) to 5 (excellent). Each focus of increased activity was then localized and given a probability of malignancy using a five-point scale. The average image quality score was similar for both UC and AC images. At the time of the positron emission tomography (PET) scans, 127 lesions (63 liver metastases, 9 retroperitoneal lesions, 50 peritoneal or bowel lesions, and 5 pancreatic carcinomas) were revealed by pathological or correlative studies. The areas under the FROC curves were consistently greater for AC images (range 0.8663-0.8867) than for UC images (range 0.7774 -0.8613). Overall, the difference between the AC images and the UC images was significant (P=0.019). In particular, correction for attenuation increased the sensitivity regardless of the location of the lesions. In conclusion, correction for attenuation significantly improves the diagnostic accuracy of FDG-PET for abdominal staging of neoplasms, without impairing the image quality. [less ▲]Detailed reference viewed: 18 (2 ULg) Fractionation and reconstitution experiments provide insight into the role of gluten and starch interactions in pasta qualityDelcour, Jan; Vansteelandt, J.; Hythier, M. C. et alin Journal of Agricultural and Food Chemistry (2000), 48(9), 3767-3773Commercial durum wheat (Triticum durum desf.) semolina was fractionated into starch, gluten, and water extractables. Starch surface proteins and surface lipids were removed, and two starches with ... [more ▼]Commercial durum wheat (Triticum durum desf.) semolina was fractionated into starch, gluten, and water extractables. Starch surface proteins and surface lipids were removed, and two starches with manipulated granule size distributions were produced to influence starch properties, affecting its interaction with other semolina components. Reconstituted spaghetti was made with untreated (control) or treated starches. The pasta made from the starting semolina material had lower cooking time and was of lower quality than the samples made from reconstituted material. This was not due to changes in gluten properties as a result of the first step of the fractionation process. For the reconstituted samples, starch interaction behavior was not changed after surface protein or surface lipid removal. Starch surface properties thus do not influence the starch interaction behavior, indicating that starch-gluten interaction in raw (uncooked) pasta is mainly due to physical inclusion. All reconstituted pasta samples also had generally the same cooking quality. It was concluded that the small changes in starch gelatinization behavior, caused by the above;mentioned starch modifications, are of little importance for pasta quality. [less ▲]Detailed reference viewed: 26 (0 ULg) A simple method for neutrophils isolaton in horseVotion, Dominique ; Harmegnies, N. F.; Lekeux, Pierre in European Journal of Nuclear Medicine (2000), 27Detailed reference viewed: 9 (0 ULg) Principal component analysis based on robust estimators of the covariance or correlation matrix: Influence functions and efficienciesCroux, C.; Haesbroeck, Gentiane in Biometrika (2000), 87(3), 603-618A robust principal component analysis can be easily performed by computing the eigenvalues and eigenvectors of a robust estimator of the covariance or correlation matrix. In this paper we derive the ... [more ▼]A robust principal component analysis can be easily performed by computing the eigenvalues and eigenvectors of a robust estimator of the covariance or correlation matrix. In this paper we derive the influence functions and the corresponding asymptotic variances for these robust estimators of eigenvalues and eigenvectors. The behaviour of several of these estimators is investigated by a simulation study. It turns out that the theoretical results and simulations favour the use of S-estimators, since they combine a high efficiency with appealing robustness properties. [less ▲]Detailed reference viewed: 24 (6 ULg) Le potentiel evoque cognitif P300 (II): variabilite interindividuelle et application clinique en psychopathologie.Hansenne, Michel in Neurophysiologie Clinique = Clinical Neurophysiology (2000), 30(4), 211-31The P300 wave is one of the cognitive components of the event-related potential (ERP) that is used to investigate the cognitive processes, and which can be used to study patient populations with a variety ... [more ▼]The P300 wave is one of the cognitive components of the event-related potential (ERP) that is used to investigate the cognitive processes, and which can be used to study patient populations with a variety of psychiatric disorders. Its clinical utility has been increased by the identification of factors that contribute to the variability in its amplitude and latency. However, its value as a diagnostic index has not been entirely established. It can provide a useful recording of patients' information processing, and indicate the severity of the clinical state and its possible evolution. It can also assist in determining what therapeutic approach to adopt. In the present review, the findings in the literature concerning interindividual variation in the P300 wave are first described; several variables significantly influence the amplitude and latency of this wave, such as age, gender, intelligence and personality. Following this, the relevance of the data in the literature on the clinical applications of P300 in psychopathology is examined, including the studies undertaken to obtain an objective diagnostic index for mental disorders and also those carried out to assess the problems concerning the interpretation of information connected with the mental pathologies examined. P300-associated findings on dementia, schizophrenia, depression, alcoholism, drug addiction, anxiety disorders (panic disorder, obsessive-compulsive disorder, and post-traumatic stress syndrome) and on personality disorders (schizoid, antisocial or borderline personality disorder) have been examined in detail. [less ▲]Detailed reference viewed: 99 (8 ULg) The cognitive management of daily life activities in patients with mild to moderate Alzheimer's disease me in a day care centre : A case reportAdam, Stéphane ; Van der Linden, Martial ; Juillerat, Anne- Claude et alin Neuropsychological Rehabilitation (2000), 10(5), 485-509The day care centre appears to be a structure especially well suited for the management of mild to moderate Alzheimer patients. It constitutes a place in which performance in everyday life activities can ... [more ▼]The day care centre appears to be a structure especially well suited for the management of mild to moderate Alzheimer patients. It constitutes a place in which performance in everyday life activities can be explored, and optimisation strategies can be installed before they are used at home. Another objective of the day care centre might also be to provide caregivers with support and ease the burden that the daily care of a demented patient represents. Finally, it may also help to alleviate the patient's loneliness. In this perspective, we describe the general organisation of the recently-created day care centre at the University Hospital of Liege. We also present the assessment and intervention programme which was conducted in this day care centre in order to reduce the generalised apathy and depressed mood observed in a 70-year-old Alzheimer patient (AM). This programme aimed at restoring a leisure activity (knitting) at home by proposing several adaptations designed to minimise the impact of AM's cognitive deficits on knitting activity. While an aggravation of her memory deficits was observed, the intervention significantly decreased AM's apathy and depressed mood as well as her husband's burden. [less ▲]Detailed reference viewed: 136 (8 ULg) Probing Organization and Structural Characteristics of Alkanethiols Adsorbed on Gold and of Model Alkane Compounds through their Valence Electronic Structure: an Ultraviolet Photoelectron Spectroscopy StudyDuwez, Anne-Sophie ; Pfister-Guillouzo, G.; Delhalle, Joseph et alin Journal of Physical Chemistry B (2000), 104In this paper we report an ultraviolet photoelectron spectroscopy (UPS) study of saturated alkane chains in various configurations and conformations. The dependence of the valence spectra on molecular ... [more ▼]In this paper we report an ultraviolet photoelectron spectroscopy (UPS) study of saturated alkane chains in various configurations and conformations. The dependence of the valence spectra on molecular structure characteristics has been assessed by comparing the results obtained from n-alkanethiol, R,ö-alkanedithiol, and R-cycloalkyl-ö-alkanethiol monolayers adsorbed on gold, and from gas-phase model alkane compounds. The differences between the spectra reflect directly the structural changes induced in the electronic structure of the alkane chains. We have determined the type of folding sequences adopted in a 1,12-dodecanedithiol monolayer. Angular dependent measurements and investigations on the photoelectron attenuation length have evidenced very fine structural differences between films obtained on deposited gold films, annealed gold films, and gold single crystals [less ▲]Detailed reference viewed: 11 (0 ULg) Using the classification model of an electronic nose to assign unknown malodours to environmental sources and to monitor them continuouslyNicolas, Jacques ; Romain, Anne-Claude ; Wiertz, Véronique et alin Sensors and actuators. B, Chemical (2000), 69(3), 366-371The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water ... [more ▼]The paper provides some considerations resulting from measurements with electronic noses around real sources of malodour in the environment: compost facilities, printing houses, paint shops, waste water treatment plants, rendering plants, settling ponds of sugar factories. The study aims at supplying the concrete information requested by the final user in the field: either a warning signal when the malodour level exceeds some given threshold value, the identification of the source of an odour detected on site, or on-line identification and monitoring of an odour in the field. Very simple instruments are used, either in the laboratory or directly in the field, with a home-made portable e-nose, based on tin oxide sensors. Even with such simple operating conditions, the classification results with DA and PCA are fairly good. The classification functions calibrated with the statistical procedure, on the basis of the learning phase, are used to recognise and to monitor a given malodour. This odour is sometimes mixed with other odorous interferences in the field. The observations reveal some features useful in the frame of the development of a field detector. [less ▲]Detailed reference viewed: 61 (2 ULg) The bushlike radiation of muroid rodents is exemplified by the molecular phylogeny of the LCAT nuclear gene.Michaux, Johan ; Catzeflis, F.in Molecular Phylogenetics & Evolution (2000), 17(2), 280-93Phylogenetic relationships among 40 extant species of rodents, with an emphasis on the taxonomic sampling of Muridae and Dipodidae, were studied using sequences of the nuclear protein-coding gene LCAT ... [more ▼]Phylogenetic relationships among 40 extant species of rodents, with an emphasis on the taxonomic sampling of Muridae and Dipodidae, were studied using sequences of the nuclear protein-coding gene LCAT (lecithin cholesterol acyl transferase). Analysis of 804 bp from the exonic regions of LCAT confirmed many traditional groupings in and around Muridae. A strong support was found for the families Muridae (represented by 29 species) and Dipodidae (5 species). Compared with Sciuridae, Gliridae, and Caviomorpha, the Dipodidae family appeared the closest relative of Muridae, confirming the suprafamilial Myodonta concept. Within the speciose family Muridae, the first branching leads to the fossorial Spalacinae and semifossorial Rhyzomyinae. The remaining components of Muridae appear as a polytomy from which are issued Sigmodontinae, Calomyscinae, Arvicolinae, Cricetinae, Mystromyinae, Nesomyinae, and some Dendromurinae (Steatomys and Dendromus). This phylogeny is interpreted as the result of a bushlike radiation at the end of the early Miocene, leading to emergence of most living subfamilies. The separation between three additional taxa, Murinae, Gerbillinae, and "Acomyinae" (which comprises the genera Acomys, Deomys, Uranomys, and Lophuromys), has occurred more recently from a common ancestor issued from the main basal radiation. As previously shown by other molecular studies, the vlei rats, Otomyinae, are nested within Old World Murinae. In the same way, the zokors, Myospalacinae, appear strongly nested within the hamsters, Cricetinae. Finally, we propose a sister group relationship between Malagasy Nesomyinae and south African Mystromyinae. [less ▲]Detailed reference viewed: 35 (0 ULg) Politique et usage des manuels scolaires en mathématiques et en sciencesMonseur, Christian ; Demeuse, Marc in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (3-4), 177-183Detailed reference viewed: 18 (1 ULg) Transition rates of the resonance line doublet in the Cl I sequence, Ar II to Ge XVIBiémont, Emile ; Träbert, E.in Journal of Physics : B Atomic Molecular & Optical Physics (2000), 33Detailed reference viewed: 8 (2 ULg) The effect of electron-phonon interaction in iron-doped III-V cubic semiconductorsColignon, David ; Kartheuser, Eduard ; Villeret, Muriellein Journal of Physics : Condensed Matter (2000), 12(12), 2691-2699A theoretical study of optical absorption and emission measurements of Fe2+ as a substitutional impurity in InP and GaP is presented. A new interpretation of the low-temperature absorption spectrum is ... [more ▼]A theoretical study of optical absorption and emission measurements of Fe2+ as a substitutional impurity in InP and GaP is presented. A new interpretation of the low-temperature absorption spectrum is proposed based on a weak Jahn-Teller interaction between the electronic excited states and a local gap mode of Gamma(5) symmetry. The model also includes the crystal potential, hybridization with the orbitals of the ligands of the host crystal, spin-orbit interaction and a weak dynamic Jahn-Teller coupling of the orbital ground state of Fe2+ with transverse acoustic phonons of Gamma(3) symmetry. The theoretical model describes with good accuracy the measured positions and relative intensities of the spectral lines. In addition, the mass dependence of the local gap mode of Gamma(5) symmetry reproduces the general features of the fine structures associated with the isotopic shifts of the zero-phonon line and the contribution to the isotopic shifts arising from the difference in zero-point energy between the initial and final states of the transition is evaluated. [less ▲]Detailed reference viewed: 55 (8 ULg) Sibling cannibalism in dorada under experimental conditions. II. Effect of initial size heterogeneity, diet and light regime on early cannibalismBaras, E.; Maxi, M. Y.; Ndao, J. et alin Journal of Fish Biology (2000), 57Detailed reference viewed: 15 (3 ULg) L'évaluation externe en lecture menée à l'entrée en 3e secondaire : morceaux choisisLafontaine, Dominique in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (1-2), 7-11En octobre 1998, une évaluation externe en lecture s'est déroulée dans un échantillon représentatif de classes de 3e année de l'enseignement secondaire en Communauté française de Belgique. A cette ... [more ▼]En octobre 1998, une évaluation externe en lecture s'est déroulée dans un échantillon représentatif de classes de 3e année de l'enseignement secondaire en Communauté française de Belgique. A cette occasion, on a non seulement évalué dans quelle mesure les élèves maîtrisent certaines des compétences essentielles reprises dans les socles, mais aussi tenté de comprendre les rapports complexes que les adolescents entretiennent avec le monde de l'écrit. [less ▲]Detailed reference viewed: 55 (14 ULg) The antiangiogenic factor 16K PRL induces programmed cell death in endothelial cells by caspase activationMartini, J. F.; Piot, C.; Humeau, L. M. et alin Molecular Endocrinology (2000), 14(10), 1536-49We asked whether the antiangiogenic action of 16K human PRL (hPRL), in addition to blocking mitogen-induced vascular endothelial cell proliferation, involved activation of programmed cell death. Treatment ... [more ▼]We asked whether the antiangiogenic action of 16K human PRL (hPRL), in addition to blocking mitogen-induced vascular endothelial cell proliferation, involved activation of programmed cell death. Treatment with recombinant 16K hPRL increased DNA fragmentation in cultured bovine brain capillary endothelial (BBE) and human umbilical vein endothelial (HUVE) cells in a time- and dose-dependent fashion, independent of the serum concentration. The activation of apoptosis by 16K hPRL was specific for endothelial cells, and the activity of the peptide could be inhibited by heat denaturation, trypsin digestion, and immunoneutralization, but not by treatment with the endotoxin blocker, polymyxin-B. 16K hPRL-induced apoptosis was correlated with the rapid activation of caspases 1 and 3 and was blocked by pharmacological inhibition of caspase activity. Caspase activation was followed by inactivation of two caspase substrates, poly(ADP-ribose) polymerase (PARP) and the inhibitor of caspase-activated deoxyribonuclease (DNase) (ICAD). Furthermore, 16K hPRL increased the conversion of Bcl-X to its proapoptotic form, suggesting that the Bcl-2 protein family may also be involved in 16K hPRL-induced apoptosis. These findings support the hypothesis that the antiangiogenic action of 16K hPRL includes the activation of programmed cell death of vascular endothelial cells. [less ▲]Detailed reference viewed: 19 (4 ULg) La place quantitative et qualitative de la viande dans notre alimentation.Mary, Arnaud; Sindic, Marianne in Dieta (2000), (22), 6-11Detailed reference viewed: 26 (0 ULg) Dual Formulations for the Modeling of Thin Electromagnetic Shells using Edge ElementsGeuzaine, Christophe ; Dular, Patrick ; Legros, Willy in IEEE Transactions on Magnetics (2000), 36(4), 799-803Detailed reference viewed: 12 (1 ULg) Pharma-clinics. Le medicament du mois. La levofloxacine (Tavanic).Scheen, André in Revue Médicale de Liège (2000), 55(11), 1015-7Levofloxacin, the (-)-(S)-enantiomer isolated from the racemate ofloxacin, is launched by Aventis under the trade name of Tavanic. This new oral and parenteral antibiotic belongs to the fluoroquinolone ... [more ▼]Levofloxacin, the (-)-(S)-enantiomer isolated from the racemate ofloxacin, is launched by Aventis under the trade name of Tavanic. This new oral and parenteral antibiotic belongs to the fluoroquinolone family and exerts a bactericidal activity upon a large spectrum of microorganisms, including Gram negative and Gram positive bacilli (among which Streptococcus pneunomiae), and atypical respiratory pathogens. It also has interesting pharmacokinetic properties. Besides the classical indications of other fluoroquinolones (especially complicated urinary tract infections, including pyelonephritis, and severe skin and soft tissue infections), levofloxacin is indicated for the treatment of acute sinusitis, acute exacerbations of chronic bronchitis and community-acquired pneumonia. [less ▲]Detailed reference viewed: 103 (4 ULg) Proteolytic cleavage confers nitric oxide synthase inducing activity upon prolactinCorbacho, A. M.; Nava, G.; Eiserich, J. P. et alin Journal of Biological Chemistry (2000), 275(18), 13183-6Prolactin (PRL), originally associated with milk secretion, is now known to possess a wide variety of biological actions and diverse sites of production beyond the pituitary. Proteolytic cleavage is a ... [more ▼]Prolactin (PRL), originally associated with milk secretion, is now known to possess a wide variety of biological actions and diverse sites of production beyond the pituitary. Proteolytic cleavage is a common post-translational modification that can either activate precursor proteins or confer upon the peptide fragment unique biological actions not exerted by the parent molecule. Recent studies have demonstrated that the 16-kDa N-terminal proteolytic cleavage product of PRL (16K-PRL) acts as a potent inhibitor of angiogenesis. Despite previous demonstrations of 16K-PRL production in vivo, biological functions beyond its antiangiogenic actions remain unknown. Here we show that 16K-PRL, but not full-length PRL, acts to promote the expression of the inducible isoform of nitric oxide synthase (iNOS) and nitric oxide (*NO) production by pulmonary fibroblasts and alveolar type II cells with potency comparable with the proinflammatory cytokines interleukin-1beta, interferon gamma, and tumor necrosis factor alpha. The differential effect of 16K-PRL versus PRL occurs through a receptor distinct from known PRL receptors. Additionally, pulmonary fibroblasts express the PRL gene and endogenously produce 16K-PRL, suggesting that this pathway may serve both autocrine and paracrine roles in the regulation of *NO production. These results reveal that proteolytic cleavage of PRL confers upon this classical hormone potent iNOS inducing activity, suggesting its role in inflammatory/immune processes. [less ▲]Detailed reference viewed: 19 (1 ULg) Partial purification of the soluble glutathione S-transferases of two aphid species, Aulacorthum solani and Acyrthosiphon pisumFrancis, Frédéric ; Haubruge, Eric ; Gaspar, C. et alin Chemico-Biological Interactions (2000), 133Detailed reference viewed: 10 (2 ULg) Forest canopy perforation in time and space in Amazonian Ecuador.Salvador-Van Eysenrode, D; Bogaert, Jan ; Van Hecke, P et alin Acta Oecologica: International Journal of Ecology (2000), 21(4-5), 285-291Detailed reference viewed: 11 (1 ULg) Donor lymphocyte infusion to eradicate recurrent host hematopoiesis after allogeneic BMT for sickle cell disease.Baron, Frédéric ; Dresse, Marie-Françoise ; Beguin, Yves in Transfusion (2000), 40(9), 1071-3BACKGROUND: Donor lymphocyte infusion (DLI) is currently standard therapy for relapse of malignancies after allogeneic BMT. Several observations suggest that both normal and leukemic progenitor cells of ... [more ▼]BACKGROUND: Donor lymphocyte infusion (DLI) is currently standard therapy for relapse of malignancies after allogeneic BMT. Several observations suggest that both normal and leukemic progenitor cells of host origin constitute effective target cells for donor-derived lymphocytes. To prevent relapse of sickle cell disease (SCD), a child with evidence of decreasing mixed chimerism received DLIs 8 months after allogeneic BMT for SCD. CASE REPORT: A 4-year-old child who was homozygous for SCD underwent a transplantation of bone marrow from his fully HLA-matched sister. Routine detection of sex chromosomes in bone marrow cells evidenced decreasing mixed chimerism, which heralded a probably imminent recurrence of the disease. The patient received two DLIs in graded incremental doses on Days 234 and 267. One month later, he developed grade 2 acute GVHD that responded well to corticosteroids and cyclosporine. RESULTS: DLI resulted in complete donor chimerism within 2 months of the second infusion. Now, 2 years after the second DLI, the patient is in excellent condition, with normal Hb and excellent growth and development. CONCLUSION: This is the first report of successful use of DLI in a patient with probable imminent SCD recurrence after allogeneic BMT. It shows that DLI can displace residual host HPCs in case of recurrence of nonmalignant disease after allogeneic BMT. [less ▲]Detailed reference viewed: 29 (3 ULg) Iron Oxidation and Deposition in the Biofilm Covering Montacuta ferruginosa (Mollusca, Bivalvia).Gillan, D.; Warnau, M.; De Vrind-De Jong, E. W. et alin Geomicrobiology Journal (2000), 17(2), 141-150Detailed reference viewed: 23 (2 ULg) Les arcanes de la prescription de l'action publiqueJacobs, Ann in Revue de Jurisprudence de Liège, Mons et Bruxelles (2000)Detailed reference viewed: 16 (0 ULg) Répartition du Lézard des murailles, Podarcis muralis (Laurenti, 1768), dans le bassin de la Vesdre. Données nouvelles sur l'écologie de l'espèce et sur l'influence des facteurs anthropiquesGraitson, Eric in Naturalistes Belges (Les) (2000), 81, 4Detailed reference viewed: 57 (5 ULg) Sensitivity analysis for the EPIK vulnerability assessment in a local karstic aquiferGogu, Radu Constantin; Dassargues, Alain in Hydrogeology Journal (2000), 8(3), 337-345Applying the EPIK parametric method, a vulnerability assessment has been made for a small karstic groundwater system in southern Belgium. The aquifer is a karstified limestone of Devonian age. A map of ... [more ▼]Applying the EPIK parametric method, a vulnerability assessment has been made for a small karstic groundwater system in southern Belgium. The aquifer is a karstified limestone of Devonian age. A map of intrinsic vulnerability of the aquifer and of the local water-supply system shows three vulnerability areas. A parameter-balance study and a sensitivity analysis were performed to evaluate the influence of single parameters on aquifer-vulnerability assessment using the EPIK method. This approach provides a methodology for the evaluation of vulnerability mapping and for more reliable interpretation of vulnerability indices for karst groundwater resources. [less ▲]Detailed reference viewed: 135 (7 ULg) The increase of the ionospheric activity as measured by GPSWarnant, René ; Pottiaux, Ericin Earth, Planets, and Space [=EPS] (2000), 52(11), 1055-1060Detailed reference viewed: 24 (8 ULg) A comparison of respiratory pathways in fully habituated and normal non-organogenic sugarbeet callusBisbis, Badia; Wagner, Anneke; Kevers, Claire et alin Journal of Plant Physiology (2000), 156(3), 312-318The respiration of cells and isolated mitochondria of a habituated non-organogenic (HNO) cell line (auxin- and cytokinin-independent) and of a normal (N) cell line (auxin- and cytokinin-requiring) from ... [more ▼]The respiration of cells and isolated mitochondria of a habituated non-organogenic (HNO) cell line (auxin- and cytokinin-independent) and of a normal (N) cell line (auxin- and cytokinin-requiring) from sugarbeet (Beta vulgaris L.) was investigated. Oxygen uptake by both cells and mitochondria of the HNO fine was higher than that of the N line. Respiration in the presence of cyanide (i.e. capacity of the alternative pathway) was also higher in the HNO callus as compared with the N one. The measurements of O-2 uptake from isolated HNO and N mitochondria showed that addition of a mixture of substrates (NADH, succinate, malate and NAD) resulted in a higher respiration via the CN-resistant pathway in mitochondria From HNO cells. The activity of cytochrome c oxidase was twice as high as in the N cells as compared with the HNO cells. Immunoblots also showed that a higher alternative oxidase protein was present in HNO cells than in the N cells. A model showing the relationships between the different metabolic pathways previously studied in the HNO cells and the higher respiration via the CN-resistant pathway in the HNO cells is proposed. [less ▲]Detailed reference viewed: 9 (1 ULg) Ecological, morphological and allozymic differentiation between diploid and tetraploid knapweeds (Centaurea jacea) from a contact zone in the Belgian ArdennesHardy, O. J.; Vanderhoeven, SONIA ; De Loose, M. et alin New Phytologist (2000), 146(2), 281-290In the northeastern part of Belgium, the Centaurea jacea complex shows extensive morphological variation and is represented by a diploid (2n = 22) and a tetraploid (2n = 44) cytotype. Polysomic ... [more ▼]In the northeastern part of Belgium, the Centaurea jacea complex shows extensive morphological variation and is represented by a diploid (2n = 22) and a tetraploid (2n = 44) cytotype. Polysomic inheritance of allozyme markers in the tetraploids, suggesting autopolyploidy, is here demonstrated for the first time. In order to test whether the tno cytotypes occupy distinct habitats and possess different gene pools, patterns of allozymic and morphological variation were investigated in relation to ploidy level and site characteristics in 26 populations from the Belgian Ardennes. The two cytotypes showed a parapatric distribution, the diploids occurring at higher elevations (mostly above 500 m) than the tetraploids (mostly below 500 m). Three mixed populations were found near the contact zone of the two cytotypes. Within the mixed populations no triploid plant and no evidence for gene flow between cytotypes were found, despite widely overlapping flowering periods. The two cytotypes can be distinguished on the basis of morphological traits and enzymatic gene pools. The congruence of morphological and allozymic variation with chromosome numbers suggests a secondary contact between the two cytotypes with limited gene flow between them. The origin and persistence of the parapatric distribution are discussed. [less ▲]Detailed reference viewed: 21 (0 ULg) Evidence for expression of some Microtubule-associated Protein 1B in neurons as a plasma membrane glycoprotein.Franzen, Rachelle ; Tanner, Sandy; Jaffe, Howard et alin Journal of Neurochemistry (2000), 75Detailed reference viewed: 8 (0 ULg) La néosporose chez la chèvre : résultats de deux enquêtes sérologiques dans l'Ouest de la FranceChartier, C.; Baudry, C.; Losson, Bertrand et alin Point Vétérinaire (2000), 31Detailed reference viewed: 39 (0 ULg) Magnetic fabric and deformation in charnockitic igneous rocks of the Bjerkreim-Sokndal layered intrusion (Rogaland, Soutwest Norway)Bolle, Olivier ; Diot, Hervé; Duchesne, Jean-Clair in Journal of Structural Geology (2000), 22Detailed reference viewed: 7 (2 ULg) Extensions des techniques de reparation valvulaire mitrale: chirurgie de l'endocardite et des tumeurs valvulairesRadermecker, M. A.; Gach, Olivier ; Henrottaux, G. et alin Revue Médicale de Liège (2000), 55(10), 950-3Mitral valve repair has demonstrated its superiority over valve replacement. Mitral valve repair constitutes the optimal therapeutic option in case of degenerative dystrophic, rheumatic, congenital or ... [more ▼]Mitral valve repair has demonstrated its superiority over valve replacement. Mitral valve repair constitutes the optimal therapeutic option in case of degenerative dystrophic, rheumatic, congenital or ischemic mitral valve disease. These surgical techniques can also be successfully and advantageously applied in case of bacterial endocarditis or tumoral valvular disease. We report a case of staphylococcal endocarditis and another case of posterior leaflet fibroelastoma to show the place of conservative mitral surgery in these unusual indications. [less ▲]Detailed reference viewed: 32 (2 ULg) Comment je traite.... De la pharmacologie speciale a la therapeutique medicale: plaidoyer pour un enseignement privilegiant l'apprentissage au raisonnement therapeutique, de la decision a la prescription.Scheen, André in Revue Médicale de Liège (2000), 55(9), 811-6Clinical pharmacology and therapeutics are two complementary disciplines which should lead the medical student, through an optimized training, to a rational prescription of drugs, ultimate and important ... [more ▼]Clinical pharmacology and therapeutics are two complementary disciplines which should lead the medical student, through an optimized training, to a rational prescription of drugs, ultimate and important step of the medical approach. Such a learning should occur progressively throughout the medical education, focusing, first, on the therapeutic reasoning ("why?") and, second, on the practical application leading to the prescription ("how?"). The medical student should learn the difficult task of integrating disease, drug and patient, in order to optimize the benefit/risk ratio, while being informed about new concepts such as "Evidence-Based Medicine" and pharmacoeconomics. [less ▲]Detailed reference viewed: 79 (2 ULg) Crystal structure of a D-aminopeptidase from Ochrobactrum anthropi, a new member of the 'penicillin-recognizing enzyme' family.Bompard-Gilles, C.; Remaut, H.; Villeret, V. et alin Structure (2000), 8(9), 971-80BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis ... [more ▼]BACKGROUND: beta-Lactam compounds are the most widely used antibiotics. They inactivate bacterial DD-transpeptidases, also called penicillin-binding proteins (PBPs), involved in cell-wall biosynthesis. The most common bacterial resistance mechanism against beta-lactam compounds is the synthesis of beta-lactamases that hydrolyse beta-lactam rings. These enzymes are believed to have evolved from cell-wall DD-peptidases. Understanding the biochemical and mechanistic features of the beta-lactam targets is crucial because of the increasing number of resistant bacteria. DAP is a D-aminopeptidase produced by Ochrobactrum anthropi. It is inhibited by various beta-lactam compounds and shares approximately 25% sequence identity with the R61 DD-carboxypeptidase and the class C beta-lactamases. RESULTS: The crystal structure of DAP has been determined to 1.9 A resolution using the multiple isomorphous replacement (MIR) method. The enzyme folds into three domains, A, B and C. Domain A, which contains conserved catalytic residues, has the classical fold of serine beta-lactamases, whereas domains B and C are both antiparallel eight-stranded beta barrels. A loop of domain C protrudes into the substrate-binding site of the enzyme. CONCLUSIONS: Comparison of the biochemical properties and the structure of DAP with PBPs and serine beta-lactamases shows that although the catalytic site of the enzyme is very similar to that of beta-lactamases, its substrate and inhibitor specificity rests on residues of domain C. DAP is a new member of the family of penicillin-recognizing proteins (PRPs) and, at the present time, its enzymatic specificity is clearly unique. [less ▲]Detailed reference viewed: 13 (0 ULg) Le diagnostic précoce de la maladie d'Alzheimer: Apport de la neuropsychologieDelbeuck; Van der Linden, Martial ; Collette, Fabienne et alin Neurone (2000), 5Detailed reference viewed: 82 (22 ULg) Morphological And Molecular Evidence Of The Confusion Between Elodea Callitrichoides And E-Nuttallii In Belgium And Northern FranceVanderpoorten, Alain ; Lambinon, Jacques ; Tignon, M.in Belgian Journal of Botany (2000), 133(1-2), Detailed reference viewed: 38 (2 ULg) La commission d'hemovigilance du CHU.Baudoux, Etienne ; Blaffart, Francine ; Bouffioux, Christian et alin Revue Médicale de Liège (2000), 55(9), 878-80As suggested by the National Blood Council, a Hemovigilance Committee was set up in the University Hospital of Liege in 1995. A multidisciplinary discussion takes place on any action aiming at the ... [more ▼]As suggested by the National Blood Council, a Hemovigilance Committee was set up in the University Hospital of Liege in 1995. A multidisciplinary discussion takes place on any action aiming at the improvement of transfusion safety, and the follow-up of its implementation. The first issue to be discussed was the set up of a detailed documentation of all blood transfusions. The data are now recorded on a single document allowing proper identification of people and products involved, and of the eventual incidents. This document has lead to a better transfusion safety and to an improved administrative management of blood transfusion. The Commission has been coordinating two multi-centric studies analyzing the consumption of fresh blood products and the incidence of transfusion reactions. Among blood-saving policies, autologous transfusion and volume reduction of samples drawn for laboratory purposes have been discussed. Other measures were taken to improve the labeling of samples for cross-mach and to actively follow-up transfusion reactions. By its actions and advises, the Commission aims to direct strategies towards a safe and rational use of blood products. [less ▲]Detailed reference viewed: 214 (34 ULg) A potent diazoxide analogue activating ATP-sensitive K+ channels and inhibiting insulin releaseLebrun, P.; Arkhammar, P.; Antoine, M.-H. et alin Diabetologia (2000), 43Detailed reference viewed: 16 (4 ULg) Les non-recommandations dans le traitement de l'arthrose et de la polyarthrite rhumatoïde, ou pourquoi la médecine basée sur le niveau de preuve ne s'applique pas (encore) à la rhumatologieMalaise, Michel in Revue Médicale de Liège (2000), 55(5), 466-475The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can ... [more ▼]The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can be made or when mortality or well-defined morbidity are the outcomes, two conditions not really frequently encountered in rheumatology. We will discuss why rheumatology is probably not ready yet for the concept and will systematically review why "Evidence-Based Medicine" could in fact be "evidence-biased medicine". We will emphasize why evidence-based medicine can not replace the personal experience and knowledge of patients, two major corner-stones in the clinician's daily work, but should simply be an access to scientific data for the benefit of both patient and physician. [less ▲]Detailed reference viewed: 19 (2 ULg) Réhabilitation du pont barrage de Montignie-Saint-ChristopheLejeune, André ; Pirotton, Michel in Cahiers de l'Urbanisme (Les) (2000)Detailed reference viewed: 19 (2 ULg) Bulletin bibliographique de la Société Rencesvals, 1999-2000Horrent, Jacques ; Henrard, Nadine in Bulletin bibliographique de la Société Rencesvals (2000), (31), 208Detailed reference viewed: 18 (2 ULg) Alteration of thyroid hormones, insulin-like growth factor-I (IGF-I) and IGFBPs in finishing calves treated with dexamethasoneBertozzi, Carlo; Massart, Serge; Darras, Veerle et alin Canadian Journal of Animal Science (2000), 80Detailed reference viewed: 25 (2 ULg) Tracabilite dans la filiere animale.Portetelle, Daniel ; Haezebroeck, V.; Mortiaux, F. et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(4), Detailed reference viewed: 8 (2 ULg) Oppositions locales et dynamiques d'environnementalisationMormont, Marc ; Bertrand, Annein Espaces et Sociétés (Paris, France) (2000), (101-102), 93-112Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization ... [more ▼]Local conflicts provoke collective action that through new coalitions induce reformulations of the problems and elarge scope and scaling of environmental problems. These processes are called ecologization dynamics and are going to transform environmental politics. [less ▲]Detailed reference viewed: 124 (18 ULg) L'etude clinique du mois. Insulino-independance prolongee apres transplantation d'ilots de langerhans chez le patient diabetique de type 1: l'aboutissement d'un reve?Scheen, André in Revue Médicale de Liège (2000), 55(8), 803-5A Canadian research team recently reported a series of 7 consecutive patients with type 1 brittle diabetes who could achieve sustained excellent metabolic control in the absence of insulin therapy after ... [more ▼]A Canadian research team recently reported a series of 7 consecutive patients with type 1 brittle diabetes who could achieve sustained excellent metabolic control in the absence of insulin therapy after successful islet transplantation. This exceptional success, which contrasts with previous less favourable results, is probably due to the transplantation of a higher number of islets of good quality and to the use of a new glucocorticoid-free immunosuppressive regimen. These remarkable results which provide proof of the principle that islet transplantation can be reproducibly successful, at least for one year, may raise new hope in patients with type 1 diabetes. However, the problem of supply and demand of islets is huge and will require a careful, and probably difficult, selection of the best candidates to benefit from this new therapeutic approach. [less ▲]Detailed reference viewed: 12 (0 ULg) Les sartans face aux inhibiteurs de l'enzyme de conversion de l'angiotensine en présence d'une hypertension artérielleKrzesinski, Jean-Marie ; Sternon, J.in Revue Médicale de Bruxelles (2000), 21(3), 170-177Detailed reference viewed: 12 (2 ULg) Methodological bias in home range and mobility estimates when locating radio-tagged trout, Salmo trutta, at different time intervalsOvidio, Michaël ; Philippart, Jean-Claude ; Baras, Etiennein Aquatic Living Resources (2000), 13(6), 449-454Radio tracking has been extensively used to enhance our knowledge on the movement and home range of fish in general and salmonids in particular. However, the use of various temporal sampling protocols is ... [more ▼]Radio tracking has been extensively used to enhance our knowledge on the movement and home range of fish in general and salmonids in particular. However, the use of various temporal sampling protocols is likely to overlook fish movements, and produce experimental artefacts, the amplitude of which is unknown and may compromise comparison of fish behaviours revealed by different protocols. Starting from a day-by-day tracking study of brown treat in Belgian waters (Aisne stream, nine fish, minimum 39 daily locations per fish), we re-examined their home range and mobility, through a subsampling process, as if the fish had been located at longer time intervals (2-14 days). The estimates from subsamples were compared to the original data set in order to quantify the corresponding reduction of accuracy from observed data, and how far this could be predicted on the basis of locating frequency. The results clearly indicate that all intervals longer than one day generally generate substantial biases (reduction of accuracy from 0 to 82% for home range and from 5 to 92% for mobility) but these can be partly corrected through the use of predictive models. This analysis demonstrates that any comparison between studies relying on different locating frequencies can generate some ambiguity when interpreting biological phenomena or geographical differences. (C) 2000 Ifremer/CNRS/INRA/IRD/Cemagref/Editions scientifrques et medicales Elsevier SAS. [less ▲]Detailed reference viewed: 128 (5 ULg) Is the external beam PIXE method suitable for determining ancient silver artifact fineness?Weber, Georges ; Guillaume, J.; Strivay, David et alin Nuclear Instruments & Methods in Physics Research Section B (2000), 161In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and ... [more ▼]In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and the size of the silver artifacts to be analyzed. The external PIXE method should be an answer to this problem but several questions are arising from the implementation of the technique to such a material. The aim of this paper is to specify the experimental procedure as to take into account several parameters, which could induce dramatic errors. Among them it can be pointed out the superficial enrichment in silver, arising from the dissolution of copper and copper oxide, the surface roughness effects, the great importance of the stability of the geometric conditions. The accuracy and the precision of the method are considered within the scope of the results obtained in ancient times by the cupellation with ashbone cupels. In addition. the process involved to obtain silver alloys has been studied in order to define its influence on the real fineness of the objects. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]Detailed reference viewed: 21 (3 ULg) Osmotic behaviour of in vitro produced bovine blastocysts in cryoprotectant solutions as a potential predictive test of survivalKaidi, Safia; Donnay, I.; Lambert, Philippe et alin Cryobiology (2000), 41The osmotic behavior of bovine blastocysts produced in vitro was filmed during exposure to and dilution of cryoprotectant solutions used for vitrification. The relationship between the changes in the ... [more ▼]The osmotic behavior of bovine blastocysts produced in vitro was filmed during exposure to and dilution of cryoprotectant solutions used for vitrification. The relationship between the changes in the diameter of embryos and their subsequent survival was assessed. Embryos collected on Day 6 and Day 7 postinsemination were exposed to 10% glycerol (GLY) for 5 min, 10% GLY + 20% ethylene glycol (EG) for 5 min, and 25% Gly + 25% EG for 30 s, before dilution in 0.85 M galactose and finally in embryo transfer freezing medium (ETF). Embryos that had a higher probability of survival behaved as perfect osmometers, shrinking, reexpanding, or swelling according to an identical pattern, whereas embryos that deviated from this standard usually did not survive. The initial embryo diameter, duration of shrinkage and expansion in 10% glycerol, duration of reexpansion in ETF, and final embryo diameter were clearly predictive of the ability to hatch after culture in vitro. On a given day postinsemination, larger blastocysts were more likely than smaller blastocysts to survive and hatch after exposure to cryoprotectants with or without vitrification. [less ▲]Detailed reference viewed: 26 (0 ULg) La douleur pelvienne chez le patient oncologiqueJansen, Nicolas ; Nickers, Philippe ; Devoghel, Jean-Claude in Oncologie (2000), 2(4), 187-200Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On ... [more ▼]Pelvic pain is a common problem in the general population. In cancer patients this pain can be secondary to tumor activity or recent tumor related interventions (surgery, radiotherapy, chemotherapy). On the other hand cancer patients can also suffer from not cancer related pain. Cancer related pain is often chronic. Whatever the cause of this pain, an important psychological factor is often present, if not attributing to the pathogenesis of the pain, then as an secondary effect from the pain. Managing pelvic pain requires knowledge of the regional anatomy. A general overview is given of the approach to an oncological patient presenting with pelvic pain. Three different possibilities are discussed: (1) pain in a patient without a presently known pelvic or abdominal malignancy, (2) pain in a patient treated recently for a tumor in the pelvic area or lower abdomen, (3) pain in an so far untreated patient with a known tumor. Finally an overview of treatment options is presented. [less ▲]Detailed reference viewed: 167 (5 ULg) Les acteurs d'un système de justice pénale européenFlore, Daniel in L’espace judiciaire pénal européen après Tampere (2000)Detailed reference viewed: 37 (3 ULg) Theoretical analysis of a dynamic thermoconvective pattern in a circular containerDauby, Pierre ; Colinet, Pierre; Johnson, Duanein Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (2000), 61(3), 2663-2668Detailed reference viewed: 6 (0 ULg) Micropore size distributions of activated carbonsBlacher, Silvia ; Sahouli, Bendida; Heinrichs, Benoît et alin Langmuir (2000), 16(16), 6754-6756Detailed reference viewed: 40 (7 ULg) Effect of a 30-minute infusion of dobutamine hydrochloride on hind limb blood flow and hemodynamics in halothane-anesthetized horsesRaisis, Anthea L; Young, Lesley E; Blissitt, Karen J et alin American Journal of Veterinary Research (2000), 61(10), 1282-1288OBJECTIVE: To evaluate the hemodynamic effects of dobutamine hydrochloride (0.5 microg/kg of body weight/min) in halothane-anesthetized horses. ANIMALS: 6 adult Thoroughbred horses. PROCEDURE: Anesthesia ... [more ▼]OBJECTIVE: To evaluate the hemodynamic effects of dobutamine hydrochloride (0.5 microg/kg of body weight/min) in halothane-anesthetized horses. ANIMALS: 6 adult Thoroughbred horses. PROCEDURE: Anesthesia was induced by use of romifidine (100 microg/kg) and ketamine (2.2 mg/kg), IV. Anesthesia was maintained by halothane (end-tidal concentration 0.9 to 1.0%). Aortic, left ventricular, and right atrial pressures were measured, using catheter-mounted strain gauge transducers. Cardiac output (CO), velocity time integral, maximal aortic blood flow velocity and acceleration, and left ventricular preejection period and ejection time were measured from aortic velocity waveforms obtained by transesophageal Doppler echocardiography. Velocity waveforms were recorded from the femoral vessels, using Doppler ultrasonography. The time-averaged mean velocity and early diastolic deceleration slope (EDDS) were measured. Pulsatility index (PI) and volumetric flow were calculated. Microvascular perfusion was measured in the semimembranosus muscles by laser Doppler flowmetry. Data were recorded 60 minutes after induction of anesthesia (control) and at 15 and 30 minutes after start of an infusion of dobutamine (0.5 microg/kg/min). RESULTS: Aortic pressures were significantly increased during the infusion of dobutamine. No change was observed in the indices of left ventricular systolic function including CO. Femoral arterial flow significantly increased, and the PI and EDDS decreased. No change was observed in the femoral venous flow or in microvascular perfusion. CONCLUSIONS AND CLINICAL RELEVANCE: At this dosage, dobutamine did not alter left ventricular systolic function. Femoral blood flow was preferentially increased as the result of local vasodilatation. The lack of effect of dobutamine on microvascular perfusion suggests that increased femoral flow is not necessarily associated with improved perfusion of skeletal muscles [less ▲]Detailed reference viewed: 122 (1 ULg) Hydrodynamical and ecosystem processes in ice-covered seas of the Southern and Northern HemispheresGoffart, Anne ; Hecq, Jean-Henri in Journal of Marine Systems (2000), 27Preface of the 30th International Liège Colloquium on Ocean Hydrodynamics Liège, Belgium (May 4–8 1998) : Hydrodynamical and ecosystem processes in ice-covered seas of the Southern and Northern ... [more ▼]Preface of the 30th International Liège Colloquium on Ocean Hydrodynamics Liège, Belgium (May 4–8 1998) : Hydrodynamical and ecosystem processes in ice-covered seas of the Southern and Northern Hemispheres. Issue of JMS edited by Anne Goffart and Jean-Henri Hecq. [less ▲]Detailed reference viewed: 12 (2 ULg) Use of a simple tin oxide sensor array to identify five malodours collected in the fieldRomain, Anne-Claude ; Nicolas, Jacques ; Wiertz, Véronique et alin Sensors and actuators. B, Chemical (2000), 62(1), 73-79A laboratory-made malodour sensing system including 12 commercial tin oxide gas sensors (Figaro Engineering) is used to identify five typical sources of olfactive annoyance: printing houses, paint shop in ... [more ▼]A laboratory-made malodour sensing system including 12 commercial tin oxide gas sensors (Figaro Engineering) is used to identify five typical sources of olfactive annoyance: printing houses, paint shop in a coachbuilding, wastewater treatment plant, urban waste composting facilities and rendering plant. In this work, all the samples are collected in the field from real malodours in uncontrollable conditions. The ability of the system to predict the origin of unknowns odoriferous samples is investigated. The test of various pre-processing data algorithms shows that the best classification results are obtained with a parameter free of the sensor base-line. The differences in sensor responses among the five odours are shown by icon plots and confirmed by principal component analysis, which highlights four representative clusters. Classification models calibrated by discriminant analysis and artificial neural network are validated on unknowns samples. Chemical relationships between the sensors and the classification results proves that the recognition is not fortuitous. In spite of the influence of environmental parameters, results demonstrate the ability of a simple system to detect and identify typical olfactive annoyances. [less ▲]Detailed reference viewed: 56 (12 ULg) Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2’-deoxyuridine (BVDU) and its arabinosyl derivative,(E)-5-(2-bromovinyl)-1-b-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinaseGrignet, Christine ; Cool, Vincent; Baudson, Nathalie et alin Cancer Gene Therapy (2000), 7Detailed reference viewed: 16 (2 ULg) GEOPHYSICAL INVESTIGATIONS OF SEISMICALLY INDUCED SURFACE EFFECTS: CASE STUDY OF A LANDSLIDE IN THE SUUSAMYR VALLEY, KYRGYZSTANHavenith, Hans-Balder ; Jongmans, D.; Abdrakhmatov, K. et alin Surveys in Geophysics (2000), 21In summer 1998, a geophysical survey including seismic profiles and electrical tomography has been carried out in the Suusamyr valley, Kyrgyzstan. The scope was to investigate surface effects induced by ... [more ▼]In summer 1998, a geophysical survey including seismic profiles and electrical tomography has been carried out in the Suusamyr valley, Kyrgyzstan. The scope was to investigate surface effects induced by the Ms = 7.3 Suusamyr earthquake, the 19th of August, 1992. In this paper, special attention is paid to the case study of a debris slide triggered by the earthquake. Seismic data are analysed by P-wave refraction technique and by surface wave inversion. Electrical tomographic profiles are processed by 2D-inversion. Using geotechnical and geological information, P-velocity models and resistivity sections are interpreted in terms of geological materials, in order to build a geological 3D model. On the basis of the latter, we carried out static finite element computations as well as static and pseudo-static calculations with Janbu’s method. Newmark displacement was computed, considering or not the influence of the shallow soft deposits. The results are compared to the real displacement observed in the field and conclusions are drawn about the mechanism of the landslide. [less ▲]Detailed reference viewed: 38 (2 ULg) What do the needles, syringes, lancets and reagent strips of diabetic patients become in the absence of a common attitude? About 1070 questionnaires in diabetic clinics.Bouhanick, B.; Hadjadj, S.; Weekers, Laurent in Diabètes & Métabolism (2000), 26(4), 288-93The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable ... [more ▼]The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable containers are available for disposal but little is known about the attitudes of patients and physicians to them. 1 070 questionnaires were completed by patients (age: 50 +/- 18 years; diabetes duration: 15 +/- 11 years; 2.8 +/- 1.1 injections per day) visiting 109 doctors. Injections were done at home (72.6%), or both at home and at work (26.6%). At home: needles, syringes, lancets and reagent strips were thrown directly into the bin in 46.9%, 49.9%, 52.2% and 67.6% of cases, respectively; and in a closed plastic bottle in 29. 6%, 28.5%, 28.9% and 19.9% of cases, respectively. Specific containers were used in 8.6% and 6.3% of cases for needles and syringes, respectively. 62% of the bottles and containers were thrown directly into the bin, whereas 15.5% were returned to a pharmacy (4.5% taken to hospitals, 2.9% were burned). At work: 63% of the patients brought their needles and syringes home for disposal, 6.9% kept suitable containers at work and 30% threw their materials directly into local bins. We conclude that awareness should be increased and the organization of the collection of used material improved. [less ▲]Detailed reference viewed: 36 (0 ULg) An automata-theoretic approach to branching-time model checkingKupferman, Orna; Vardi, Moshe Y; Wolper, Pierre in Journal of the ACM (2000), 47(2), 312-360Translating linear temporal logic formulas to automata has proven to be an effective approach for implementing linear-time model-checking, and for obtaining many extensions and improvements to this ... [more ▼]Translating linear temporal logic formulas to automata has proven to be an effective approach for implementing linear-time model-checking, and for obtaining many extensions and improvements to this verification method. On the other hand, for branching temporal logic, automate-theoretic techniques have long been thought to introduce an exponential penalty, making them essentially useless for model-checking. Recently, Bernholtz and Grumberg [1993] have shown that this exponential penalty can be avoided, though they did not match the linear complexity of non-automata-theoretic algorithms. In this paper, we show that alternating tree automata are the key to a comprehensive automata-theoretic framework for branching temporal logics. Not only can they be used to obtain optimal decision procedures, as was shown by Muller ct al., but, as we show here, they also make it possible to derive optimal model-checking algorithms. Moreover, the simple combinatorial structure that emerges from the automata-theoretic approach opens up new possibilities for the implementation of branching-time model checking, and has enabled us to derive improved space complexity bounds for this long-standing problem. [less ▲]Detailed reference viewed: 35 (0 ULg) Le controle glycemique chez le patient diabetique. Recommandations apres les etudes DCCT et UKPDI.Paquot, Nicolas ; Scheen, André ; Lefebvre, Pierre in Revue Médicale de Liège (2000), 55(5), 372-5Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies ... [more ▼]Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies showed the association between the complications of diabetes and elevated blood glucose levels. Clinical trials have also demonstrated that treatment that lowers blood glucose reduces the risks of diabetic complications (mainly microvascular complications). The control of diabetes is assessed by frequent measurements of HbA1c. A reasonable goal in type 1 diabetes is a value of HbA1c < or = 7.2%. In type 2 diabetes, the optimal goal is a value of HbA1c < or = 6.5%, but a value < or = 8% seems to be an acceptable goal in these patients. [less ▲]Detailed reference viewed: 32 (0 ULg) Des jeunes face aux institutionsGuillaume, Jean-François in Lien social et politiques (2000), 43(printemps), 113-120Un constat semble s'impoesr à tout observateur des sociétés contemporaines : les jeunes générations, plus sensibles aux changements qui affectent les différentes sphères de la vie sociale ... [more ▼]Un constat semble s'impoesr à tout observateur des sociétés contemporaines : les jeunes générations, plus sensibles aux changements qui affectent les différentes sphères de la vie sociale, expérimenteraient de nouveaux rapports aux institutions traditionnelles, tiraillés entre l'attachement et le détachement aux repères qui ont valu pour ceux qui les ont précédés. Mais on peut considérer que la jeunesse n'apparaît en tant qu'objet singulier qu'à travers une grille de lecture "institutionnalisée", largement portée par les intervenants sociaux et les acteurs politiques, et où s'affirme avant tout le dessein d'un encadrement, voire d'une réappropriation, des pratiques juvéniles. Il n'y aurait donc pas, dans les discours sur la jeunesse, de regard désintéressé, susceptible de considérer ses pratiques dans leur spécificité. Une approche sociologique de la jeunesse ne peut dès lors faire l'économie d'une réflexion critique sur les grilles de lecture communément admises et utilisées pour définir la condition contemporaine de la jeunesse. [less ▲]Detailed reference viewed: 50 (8 ULg) L'herpèsvirus bovin de type 4 : virus pathogène ou passager?Thiry, Etienne ; Markine-Goriaynoff, Nicolas; Minner, Frédéric et alin Point Vétérinaire (2000), 31Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental ... [more ▼]Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental pathogenicity. Species that are susceptible to BHV-4 include animals other than ruminants, notably cats and, surprisingly, a primate the owl monkey (Aotus trivirgatus). BHV-4 exists as a latent infection in mononuclear cells. In cattle, BHV-4 has been isolated in animals exhibiting ocular and respiratory conditions and it has been found in females with genital tract conditions such as post-partum metritis and vulvovaginitis. There is some epidemiological and experimental evidence that BHV-4 may be a cause of bovine abortion. There is no vaccine available in Europe and prevention is exclusively by hygiene measures. [less ▲]Detailed reference viewed: 57 (4 ULg) Recommandations Européennes (COST B13) en matière de prévention des lombalgiesHenrotin, Yves in Kiné (2000)Detailed reference viewed: 56 (3 ULg) Réflexions sur l'avenir de la Belgique et de BruxellesMartiniello, Marco ; Swyngedouw, Marcin Utinam : Revue de Sociologie et d'Anthropologie (2000), 3Detailed reference viewed: 5 (0 ULg) General report - Session on connectionsJaspart, Jean-Pierre in Journal of Constructional Steel Research (2000), 55As a result of a world-wide intensive research activity, a new design concept for structural moment resistant joints has been suggested and implemented in design codes. In the present paper, its ... [more ▼]As a result of a world-wide intensive research activity, a new design concept for structural moment resistant joints has been suggested and implemented in design codes. In the present paper, its background is first briefly described and the main contributions to its development are presented. As a matter of fact, because of the high number of past and ongoing researches, reports and papers devoted to this topic, an exhaustive list of all these works could not be established in a limited number of pages. The possibilities of extension of the new design concepts, which have been first developed for steel beam-to-column joints under static loading, are particularly pointed out. This aspect appears quite important as in the near future it should provide designers with a unified design approach for structural joints whatever their loading, their configurations and the nature of their constitutive material(s). [less ▲]Detailed reference viewed: 154 (6 ULg) A Topological Reconstruction Theorem for $D^{\infty}$-ModulesProsmans, Fabienne ; Schneiders, Jean-Pierre in Duke Mathematical Journal (2000), 102(1), 39-86We prove that any perfect complex of $D^{\infty}-modules may be reconstructed from its holomorphic solution complex provided that we keep track of the natural topology of this last complex. This is to be ... [more ▼]We prove that any perfect complex of$D^{\infty}-modules may be reconstructed from its holomorphic solution complex provided that we keep track of the natural topology of this last complex. This is to be compared with the reconstruction theorem for regular holonomic D-modules which follows from the well-known Riemann-Hilbert correspondence. [less ▲]Detailed reference viewed: 25 (14 ULg) Insectes et Mollusques aquatiques des étangs «Les Cours» à Bolland (Pays de Herve, Belgique)Dopagne, Claude ; Dethier, Michel in Natura Mosana (2000), 53(2), 51-64Detailed reference viewed: 55 (2 ULg) Pharma-clinics. Le medicament du mois. Le rofecoxib (Vioxx).Scheen, André in Revue Médicale de Liège (2000), 55(7), 751-3Rofecoxib (Vioxx, Merck Sharp & Dohme) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as a nonsteroidal anti-inflammatory drug (NSAID). It is indicated in the ... [more ▼]Rofecoxib (Vioxx, Merck Sharp & Dohme) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as a nonsteroidal anti-inflammatory drug (NSAID). It is indicated in the symptomatic relief of pain due to osteoarthritis. The initial oral dosage of rofecoxib is 12.5 mg once daily in adults, and this dose may be increased up to a maximal dosage of 25 mg once daily if necessary. Its clinical efficacy seems to be similar to that of other NSAIDs at maximal recommended dosages, but its safety profile, especially gastrointestinal tolerance, is much better because of the COX-2 selectivity. Ongoing clinical trials are performed in patients with rheumatoid arthritis. [less ▲]Detailed reference viewed: 25 (0 ULg) The Topology Of Lysine-Containing Amphipathic Peptides In Bilayers By Circular Dichroism, Solid-State Nmr, And Molecular ModelingVogt, B.; Ducarme, P.; Schinzel, S. et alin Biophysical Journal (2000), 79(5), 2644-56In order to better understand the driving forces that determine the alignment of amphipathic helical polypeptides with respect to the surface of phospholipid bilayers, lysine-containing peptide sequences ... [more ▼]In order to better understand the driving forces that determine the alignment of amphipathic helical polypeptides with respect to the surface of phospholipid bilayers, lysine-containing peptide sequences were designed, prepared by solid-phase chemical synthesis, and reconstituted into membranes. CD spectroscopy indicates that all peptides exhibit a high degree of helicity in the presence of SDS micelles or POPC small unilamellar vesicles. Proton-decoupled (31)P-NMR solid-state NMR spectroscopy demonstrates that in the presence of peptides liquid crystalline phosphatidylcholine membranes orient well along glass surfaces. Thenorientational distribution and dynamics of peptides labeled with (15)N at selected sites were investigated by proton-decoupled (15)N solid-state NMR spectroscopy. Polypeptides with a single lysine residue adopt a transmembrane orientation, thereby locating this polar amino acid within the core region of the bilayer. In contrast, peptides with > or = 3 lysines reside along the surface of the membrane. With 2 lysines in the center of an otherwise hydrophobic amino acid sequence the peptides assume a broad orientational distribution. The energy of lysine discharge, hydrophobic, polar, and all other interactions are estimated to quantitatively describe the polypeptide topologies observed. Furthermore, a molecular modeling algorithm based on the hydrophobicities of atoms in a continuous hydrophilic-hydrophobic-hydrophilic potential describes the experimentally observed peptide topologies well. [less ▲]Detailed reference viewed: 21 (0 ULg) Chronique semestrielle de droit communautairePartsch, Philippe-Emmanuel in Journal des Tribunaux (2000)Detailed reference viewed: 4 (0 ULg)