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See detailBankfull discharge recurrence interval in gravel bed rivers
Petit, François ULg; Pauquet, A.

in Earth Surface Processes & Landforms (1997)

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with ... [more ▼]

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with basin size. In the case of gravel-bed rivers developed on an impermeable substratum, the following equation emerges: Qb=0·087 A1·044. Bankfull discharge recurrence interval was determined by fitting maximum annual floods (Ta) into Gumbel’s distribution and then using the partial duration series (Tp) in this same distribution. Recurrence interval is below 0·7 years (Tp) for small pebble-bed rivers developed on an impermeable substratum; it reaches 1·1 to 1·5 years when the catchment size of these rivers exceeds 250km2. Rivers incised in the soft schists of the Famenne show larger channel capacity at bankfull stage, a small width/depth ratio and thus higher recurrence intervals (1·4–5·3 years with Ta and 1–4·4 years with Tp). Baseflow-dominated gravel-bed streams and sandy or silty rivers experience less frequent bankfull discharges, with a recurrence interval higher than 2 or even 3 years (Tp). [less ▲]

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See detailExtensive Ulcerative Colitis and Extraintestinal Manifestations in a Patient with Hiv Infection and Significant Cd4 T-Cell Lymphopenia
Louis, Edouard ULg; Moutschen, Michel ULg; de Marneffe, Pierre et al

in Gastroentérologie Clinique et Biologique (1997), 21(11), 884-7

We report a heterosexual patient with HIV infection and a CD4 T-cell count of 0.45 x 10(9)/L who developed mild ulcerative proctitis, sacroileitis and oligoarthiritis. While he was treated with 5 ... [more ▼]

We report a heterosexual patient with HIV infection and a CD4 T-cell count of 0.45 x 10(9)/L who developed mild ulcerative proctitis, sacroileitis and oligoarthiritis. While he was treated with 5-aminosalicylic enemas, the patient rapidly developed severe pancolitis. An emergency colectomy without procetectomy was performed. A few months later, he suffered recurrence of ulcerative proctitis, aggravation of arthritic pain and developed anterior uveitis. All symptoms disappeared after proctectomy. There was no evidence for opportunistic infection or Kaposi's sarcoma. Antineutrophil cytoplasmic antibodies were positive and the HLA-B27 antigen was present. CD4 counts were lower during the phases of active disease than during remission. This case demonstrates that severe ulcerative colitis can occur in the presence of moderate T-cell defects. In view of a recent report of remission of Crohn's disease under comparable circumstances, it is possible that the extent of T-cell involvement in both diseases is radically different. [less ▲]

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See detailInfluence du stade de maturité de la plante de maïs récoltée pour ensilage sur la composition, la digestibilité apparente, les caractéristiques de fermentation dans le rumen et les performances zootechniques chez le taurillon
Mayombo, Asangule Pierre; Dufrasne, Isabelle ULg; Hornick, Jean-Luc ULg et al

in Animal Research (1997), 46(1), 43-55

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de ... [more ▼]

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de matière sèche s'élevait à 10,7 ; 11,1 et 11,7 tonnes par hectare. Chacun de ces ensilages, distribué à des taureaux à l'engraissement, a été supplémenté par des pulpes séchées, du tourteau de soja, des sels minéraux et des vitamines. Le stade de maturité n'a pas affecté les teneurs en cendres, cendres insolubles, extrait éthéré ou protéines ; cependant une réduction significative de la teneur en fibre ADF a été enregistrée avec S3. La digestibilité de la matière sèche et de la matière organique de la ration mesurée in vivo sur des taureaux en cages à bilan ainsi que celle du maïs ensilage n'ont pas été non plus influencées par le stade de maturité. En revanche, la digestibilité de la fibre ADF a été significativement plus faible pour S3 par rapport à S1 et S2 (62,1 vs 67,2 ou 65,6 %, p < 0,05 pour la ration; 54,1 vs 63,3 ou 60,7 %, p < 0,001 pour le maïs). Quant aux potentialités du rumen à dégrader les aliments, il est à noter que la dégradabilité totale par la méthode in sacco des différents composants testés a été supérieure dans le rumen des animaux qui recevaient le maïs à teneur en matière sèche élevée. Il n'y a pas eu d'effets significatifs du stade de maturité sur les performances animales durant un essai de 5,5 mois dans le cas d'une alimentation ad libitum. A partir de l'indice de consommation, du gain total de poids vif et de la production de matière sèche par hectare, il était possible d'estimer que 13,8, 14,2 et 15,7 taurillons pouvaient être engraissés respectivement à partir des ensilages de maïs S1, S2 et S3 produits par ha. [less ▲]

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See detailThree new species of Opegraphaceae (Lichens) from the Namib desert
Egea, J.M.; Sérusiaux, Emmanuël ULg; Torrente, Pilar et al

in Mycotaxon (1997), 61

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See detailAdaptations of the hemoglobinless Antarctic icefish (Channichthyidae) to hypoxia tolerance
Feller, Georges ULg; Gerday, Charles ULg

in Comparative Biochemistry & Physiology Part A : Molecular & Integrative Physiology (1997), 118(4), 981-987

Antarctic fish of the family Channichthyidae, or icefish, represent a unique model for the study of physiological and biochemical responses to chronic hypoxia since the genes coding for hemoglobin and ... [more ▼]

Antarctic fish of the family Channichthyidae, or icefish, represent a unique model for the study of physiological and biochemical responses to chronic hypoxia since the genes coding for hemoglobin and possible myoglobin are not expressed by these teleosts. Channichthyidae have developed outstanding cardio-vascular adaptations to accommodate the lack of these hemic pigments, most of them involving the myocardium. (C) 1997 Elsevier Science Inc. [less ▲]

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See detailCertification in the meat channel.
Mortiaux, Frédéric; Renaville, Robert ULg; Gengler, Nicolas ULg et al

in Journal of Animal Science (1997), 75(1), 136

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See detailA la mémoire de Daniel P. Bobon, Mafhoud Boucebci, Amadeo Sanchez Blanque, Jean Mirel
Mormont, Christian ULg

in Acta Psychiatrica Belgica (1997), 97(Suppl. 1), 2-7

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See detailEvidence For The Assignment Of Two Strains Of Splv To The Genus Potyvirus Based On Coat Protein And 3' Non-Coding Region Sequence Data
Colinet, Dominique; Kummert, Jean; Lepoivre, Philippe ULg

in Virus Research (1997), 49(1), 91-100

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See detailcompte rendu de : Les Grecs et l'Occident. Actes du colloque de la Villa "Kérylos" (1991), Rome, 1995
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (1997), 75(1), 156-158

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See detailRheological characterization of BaTiO3 sol-gel transition
Brasseur, Alain; Michaux, Bernard; Pirard, René ULg et al

in Journal of Sol-Gel Science and Technology (1997), 9(1), 5-15

BaTiO3 gels were prepared by hydrolysis and polycondensation reactions between titanium isopropoxide and barium hydroxide in presence of methoxyethanol, methanol and water. The rheology of the sol-gel ... [more ▼]

BaTiO3 gels were prepared by hydrolysis and polycondensation reactions between titanium isopropoxide and barium hydroxide in presence of methoxyethanol, methanol and water. The rheology of the sol-gel transition was studied with a rheometer allowing low amplitude sinusoidal oscillations. Experimental data show a continuous increase in the complex viscosity along with time, showing the progressive character of the transition. The influence of synthesis operating variables was studied. The gelation time, which definition is based on viscoelastic measurements, increases exponentially when the water content is increased, when the dilution due to the methoxyethanol is reduced or when the temperature is lowered. Different growth models were used for the characterization of the particles in the solution. These models suggest that the polymerisation first produces spherical particles (mass fractals) and that these spherical particles then agglomerate to form a linear network. [less ▲]

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See detailLes antidotes en Médecine Vétérinaire
Delaunois, A.; Plume, Ch; Ansay, M. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailC.R. de M. MANCINI, Il punto su: I trovatori
Henrard, Nadine ULg

in Moyen Age (Le) (1997), CIII

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See detailKlanknabootsingen in strips
Meesters, Gert ULg

in Nederlands van nu (1997), 45(3), 82-83

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See detailLa rhinotrachéite infectieuse bovine : caractéristiques du virus, l'infection et ses manifestations cliniques
Thiry, Etienne ULg; Lemaire, Mylène; Vanderheijden, Nathalie et al

in Bulletin des Groupements Techniques Vétérinaires (1997), 568

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See detailFusion Of Bovine Leukemia Virus With Target Cells Monitored By R18 Fluorescence And Pcr Assays
Zarkik, S.; Defrisequertain, F.; Portetelle, Daniel ULg et al

in Journal of Virology (1997), 71(1),

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See detailLe sondage de Focant: lithostratigraphie et implications structurales
Boulvain, Frédéric ULg; Coen-Aubert, M.

in Memoirs of the Geological Survey of Belgium (1997), 43

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See detailLong-wavelength behavior of the exchange-correlation kernel in the Kohn-Sham theory of periodic systems
Ghosez, Philippe ULg; Gonze, X.; Godby, R. W.

in Physical Review. B : Condensed Matter (1997), 56(20), 12811-12817

The polarization dependence of the exchange-correlation (re) energy functional of periodic insulators within Kohn-Sham (KS) density-functional theory requires a O(1/q(2)) divergence in the re kernel for ... [more ▼]

The polarization dependence of the exchange-correlation (re) energy functional of periodic insulators within Kohn-Sham (KS) density-functional theory requires a O(1/q(2)) divergence in the re kernel for small vectors q. This behavior, exemplified for a one-dimensional model semiconductor, is also observed when an insulator happens to be described asa KS metal, or vice versa. Although it can occur in the exchange-only kernel, it is not found in the usual local, semilocal, or even nonlocal approximations to KS theory. We also show that the test-charge and. electronic definitions of the macroscopic dielectric constant differ from one another in exact KS theory, but are equivalent in the above-mentioned approximations. [less ▲]

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See detailTwo Members Of The Human Mageb Gene Family Located In Xp21.3 Are Expressed In Tumors Of Various Histological Origins
Lurquin, C.; De Smet, C.; Brasseur, F. et al

in Genomics (1997), 46(3), 397-408

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region ... [more ▼]

Genes of the MAGE family direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. Twelve closely related MAGE genes are located in the Xq28 region. These genes share 60-98% nucleotide identity in their coding region. The presence of homologous genes in a region of Xp21.3 has been reported previously. We obtained the complete sequence of a 42-kb stretch of this region. It contains four MAGE-related genes, which we propose to name MAGE-B1, B2, B3, and B4 (HGMW-approved symbols MAGEB1, MAGEB2, MAGEB3, and MAGEB4). The coding regions of these genes share 66-81% nucleotide identity and show 45-63% identity with those of the MAGE genes located in Xq28. Like the MAGE genes located in Xq28, the MAGE-B genes are silent in normal tissues with the exception of testis. Like MAGE-1, 2, 3, 4, 6 and 12 (HGMW-approved symbols MAGEA1, 2, 3, 4, 6, and 12), genes MAGE-B1 and MAGE-B2 are expressed in a significant fraction of tumors of various histological types. The transcription of MAGE-B1 and MAGE-B2 can be induced by 5-aza-2'-deoxycytidine, suggesting that the activation of these genes in tumors results from a demethylation process. [less ▲]

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See detailHerpesvirus Of Turkeys Homologue Of Hsv Vp16 Is Structurally Related To Varicella Zoster Virus Trans-Inducing Protein Encoded By Orf 10
Kopacek, J.; Zelnik, V.; Brasseur, Robert ULg et al

in Virus Genes (1997), 15(1), 45-52

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and ... [more ▼]

Expression of the immediate-early genes of alpha-herpesviruses is stimulated by a family of trans-inducing factors represented by VP16 of HSV-1 and ORF10 gene product of VZV. We have identified and determined the nucleotide sequence of the UL48 gene encoding the herpesvirus of turkeys (HVT) homologue of HSV VP16. The gene maps to the BamHI-J fragment and appears to be expressed in a form of bicistronic transcript together with UL49. The deduced amino acid sequence of the protein encoded by HVT UL48 gene shows 55% identity with MDV UL48 gene product. Like the majority of related proteins in other alpha-herpesviruses, the protein encoded by HVT UL48 gene lacks the acidic C-terminal tail, known to possess the transactivation capacity of HSV VP16. Hydrophobic cluster analysis has revealed that its predicted domain composition is closely related to the transactivator protein encoded by ORF10 of VZV. However, the putative amino-terminal activation domain of the HVT homologue of HSV VP16 does not contain a typical horseshoe-like hydrophobic cluster found in other alpha-herpesvirus homologues, suggesting either that it acts as a transactivator via a different activation domain or that its transactivation potential is diminished. [less ▲]

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See detailLe contrôle des juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire
Michiels, Olivier ULg

in Journal des Tribunaux (1997)

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent ... [more ▼]

La note publiée sous un arrêt prononcé par la Cour de cassation le 8 octobre 1996 fait le point sur le contrôle par les juridictions de fond sur la désignation par procureur général du magistrat compétent en application de l'article 155, alinéa 2, du Code judiciaire pour exercer les poursuites devant les juridictions répressives dans les hypothèses de concours entre des infractions de droit commun et de droit pénal social. [less ▲]

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See detailPhosphorylation of the Bovine Leukemia Virus transactivator p34Tax is required for transformation but not for transactivation.
Kettmann, Richard ULg; Grimonpont, C.; Kerkhofs, Pierre et al

in FASEB Journal (1997), 11(9), 1179

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See detailLes protéases stromales dans la progression cancéreuse mammaire
Foidart, Jean-Michel ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1997), 152(5), 229-35235-7

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several ... [more ▼]

Matrix metalloproteases represent a family of proteases secreted as latent inactive enzymes able to degrade the majority of extracellular matrix components. These enzymes are overexpressed during several pathological tissue remodelings including tumor progression and tumor invasion. It was indeed classically admitted that matrix metalloproteases involved in tumoral progression were preferentially expressed by cancerous cells. Our studies on gelatinase A and stromelysin-3 have, however, demonstrated that their messenger RNAS are detected in fibroblasts of the peritumoral stroma in human mammary carcinoma and not in the cancerous cells themselves. By immunohistochemistry, we have detected gelatinase A in the cytoplasm of fibroblasts and at the surface of the tumor cells. This membrane localization of the protein could result from its binding, following secretion by the neighbouring stromal cells, to a specific binding site expressed at the surface of the carcinoma cells. These cells are indeed able to induce an increased proteolytic activity by enhancing the transcription of these enzymes by peritumoral fibroblasts. These enzymes represent therefore potential targets for the development of new therapeutic strategies. [less ▲]

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See detailRegolazione della crescité follicolare e luteinica. Ovulazione, corpo luteo e luteolisi
Drion, Pierre ULg; Ectors, Fabien; Hanzen, Christian ULg et al

in Riproduzione dei Ruminanti (1997), 14(9), 17-25

Most ovarian follicles (99.9%) will end up with follicular atresia. During antral stages atresia depends on a reduction of FSH levels secondary to estradiol and inhibin secretions by the dominant follicle ... [more ▼]

Most ovarian follicles (99.9%) will end up with follicular atresia. During antral stages atresia depends on a reduction of FSH levels secondary to estradiol and inhibin secretions by the dominant follicle. Plasma levels in estradiol higher than 12pg/ml for at least 12 hours in bovine will cause the reversal of the negative feed-back effect of estradiol on the hypothalamus inducing the preovulatory peak of LH. So that the ovulatory discharge does not occur prematurely, the dominant follicle also secretes GnSIF which desensitises the hypohtesis to the action of GnRH. After ovulation, the corupus luteum, a true endocrine gland, develops. [less ▲]

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See detail"De l'Olympe au réseau..." Comment les philologues classiques allemands font face aux réalités contemporaines
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin (1997), 108(septembre-octobre), 6-7

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See detailAerogel compression theoretical analysis
Pirard, René ULg; Pirard, Jean-Paul ULg

in Journal of Non-Crystalline Solids (1997), 212(2-3), 262-267

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The ... [more ▼]

Several authors have empirically shown that, in aerogels, a power law exists between the mechanical moduli and the bulk density. An exponent value can be determined from mercury porosimetry curves. The shrinkage of aerogels under mercury pressure follows a buckling mechanism which links the pore size to the exerted pressure. The present study relates the exponent to the pore volume distribution which can be described by a hierarchical model valid in a large range of pore size, so a physical meaning is given to the exponent. [less ▲]

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See detailLuc et Jean-Pierre Dardenne. Vingt ans de travail en cinéma et vidéo (1976-1996)
Van Cauwenberge, Geneviève ULg; Bajomée, Danielle ULg; Delruelle, Edouard ULg et al

in Revue belge du cinéma (1997), 41(Hiver), 96

Historical and analytical overview of the Dardenne’s cinématographic and videographic work from 1976 to 1996, with an interview with Luc and Jean-Pierre Dardenne. A lot of issues about the survivor’s ... [more ▼]

Historical and analytical overview of the Dardenne’s cinématographic and videographic work from 1976 to 1996, with an interview with Luc and Jean-Pierre Dardenne. A lot of issues about the survivor’s memory, the history consciousness, the wounds of memory, the survivor’s speech ; the memory of the social struggle ; the derelction and the transformation of the society ; the résistance ; the videographic and filmic forms and patterns (landscape, face, water, reality) ; the theatrical space and the relations between theatre and cinéma. [less ▲]

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See detailThe impact of sperm precedence in malathion resistance transmission in populations of the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)
Haubruge, Eric ULg; Arnaud, Ludovic; Mignon, Jacques ULg

in Journal of Stored Products Research (1997), 33(2), 143-146

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve ... [more ▼]

Malathion resistance in the red flour beetle Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is actually a worldwide problem, and studies on resistance transmission are needed to improve insecticide resistance management. Females of Tribolium castaneum commonly mate with several males, and the last batch of male sperm preferentially fertilizes subsequent eggs. This phenomenon, a particular form of sexual selection, helps to increase resistance transmission in populations of stored product insects. We confirmed the last male sperm precedence and, in the absence of further matings, examined the evolution of mixed susceptible and malathion-resistant progeny during a 3-month period. The proportion of resistant phenotypes in female progeny was 99.6 and 3%, respectively, after the first mating with a resistant male and the second mating with a susceptible one. When females thus mated twice were isolated from males, the proportion of the resistant phenotype increased to 34.1% after 30 days. From 72 days onwards, this proportion ranged from 14.2 to 29.7%. (C) 1997, Published by Elsevier Science Ltd. [less ▲]

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See detailMolecular dissection of the insulin-like growth factor axis in the human thymus
Geenen, Vincent ULg; Kecha, Ouafae; Achour, Imane et al

in Diabetologia (1997), 40

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See detailLa torsion isolée de la rate : cas clinique et revue de la littérature
Zonderland, J. L.; Balligand, Marc ULg; Snaps, Frédéric ULg et al

in Annales de Médecine Vétérinaire (1997), 141

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence ... [more ▼]

This paper describes a case report and reviews the literature concerning isolated torsion of the splenic pedicle in a dog. Splenic torsion is found in young, large and deep-chested dogs with a prevalence of 3.5 to 6%. The pathogenesis of isolated splenic torsion is unknown, Clinical signs and diagnostic procedures are non specific. Only sonographic changes are valuable in performing an etiologic diagnosis, The surgical treatment consists in a splenectomy, An early diagnosis and surgical treatment usually lead to a good prognosis. [less ▲]

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See detailA. ANGENENDT, Heilige und Reliquien, Munich, 1994
George, Philippe ULg

in Francia. 1, Mittelalter (1997)

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See detailFreeze-dried resorcinol-formaldehyde gels
Blacher, Silvia ULg; Pirard, René ULg; Pirard, Jean-Paul ULg et al

in Journal of Non-Crystalline Solids (1997), 212(2-3), 250-261

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer ... [more ▼]

The texture of resorcinol-formaldehyde gels, previously synthesized by Pekala et al. [1-6], but dried by freeze-drying was studied. The freeze-dried gels present a complex porous structure from nanometer to micrometer length-scale. Taking a standard freezing rate, we study in detail the influence of the molar ratio resorcinol/catalyst on the texture, This molar ratio is one of the parameters under consideration which can lead to a tailoring of the dried gel texture in order to develop adsorbents or catalyst supports of controlled porosity. Characterization methods include nitrogen adsorption-desorption (including the classical and the fractal interpretations), mercury porosimetry, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS). [less ▲]

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See detailLes lipoxygénases du soja.
Fauconnier, Marie-Laure ULg; Marlier, M.

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(2), 125-141

Dans cet article de synthèse, les auteurs font le point sur les connaissances actuelles dans le domaine des lioxygénases du soja. Une attention particulière est portée à la compréhension des mécanismes ... [more ▼]

Dans cet article de synthèse, les auteurs font le point sur les connaissances actuelles dans le domaine des lioxygénases du soja. Une attention particulière est portée à la compréhension des mécanismes réactionnels (substrats, inhibiteurs, site actif, etc.). Le rôle physiologique ainsi que l'utilisation de cet enzuyme dans les industries agroalimentaires et en biotechnologie sont également abordés. [less ▲]

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See detailInterobserver agreement on MNA nutritional scale of hospitalized elderly patients
Gazzotti, C.; Pepinster, A.; Petermans, Jean ULg et al

in Journal of Nutrition, Health & Aging (The) (1997), 1

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See detailHair follicle involvement in herpes zoster
Nikkels, Arjen ULg; Pierard, Gérald ULg

in Virchows Archiv : An International Journal of Pathology (1997), 430

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See detailTiming effect of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice.
Coucke, Philippe ULg; Lin-Quan, Sun; Vogel, Charles-André et al

in Cancer Research (1997), 57

Timing effects of radioimmunotherapy (HIT) combined with external beam radiotherapy (RT) were assessed In human colon carcinoma xe nografts. Initially, dose effects offractlonated RT and RIT were ... [more ▼]

Timing effects of radioimmunotherapy (HIT) combined with external beam radiotherapy (RT) were assessed In human colon carcinoma xe nografts. Initially, dose effects offractlonated RT and RIT were evaluated separately. Then, 30 Gy RT (10 fractions over 12 days) were combined with three weekly Lv. injections of 200 g@Ci of 131I-labeled anti-carcino embryonic antigen monoclonal antibodies in four different treatment schedules. RIT was given either prior to, concurrently, Immediately after, or 2 weeks after RT administration. The longest regrowth delay (RD) of 105 days was observed in mice treated by concurrent administration of RT and lilT, whereas the RDs of RT and RIT alone were 34 and 20 days, respectively. The three sequential combination treatments produced sig nificantly shorter RDs ranging from 62 to 70 days. The tumor response represented by the minimal volume (MV) also showed that concurrent administration of RT and RIT gave the best result, with a mean MV of 4.5% as compared to MVs from 26 to 53% for the three sequential treatments. The results were confirmed In a second experiment, In which a RT of 40 Gy was combined with an identical lilT as above (three injections of 200 g&Ci of ‘31I-labeled monoclonal antibodies). At compa rable toxicity levels, the maximum tolerated RT or BIT alone gave shorter RDs and less tumor shrinkage compared to slinultaneous RT+RIT. These results may be useful for designing clinical protocols ofcombined RIT and RT. [less ▲]

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See detailRisultati clinici ed angiografici immediati ed a lungo termine dello stent Wiktor nel trattamento delle occlusioni coronariche croniche.
Anzuini, A.; Rosanio, S.; Legrand, Victor ULg et al

in Giornale italiano di cardiologia (1997), 27(9), 881-91

BACKGROUND: Percutaneous transluminal coronary angioplasty (PTCA) of chronic total coronary artery occlusions is associated with very high restenosis and reocclusion rates. Coronary stenting has been ... [more ▼]

BACKGROUND: Percutaneous transluminal coronary angioplasty (PTCA) of chronic total coronary artery occlusions is associated with very high restenosis and reocclusion rates. Coronary stenting has been proposed as a means of improving outcome. However, the Wiktor device for chronic coronary occlusion has never been tested in a large patient sample. This study reports the first multicenter experience with the Wiktor stent for treatment of chronic occlusions. METHODS: From January 1993 to December 1996, 89 consecutive patients with 91 chronic occlusions underwent Wiktor stent implantation after successful PTCA. Post-stenting regimen consisted of coumadin plus aspirin in the first 49 (55%) patients and aspirin plus ticlopidine in the following 40 (45%). RESULTS: Stenting was successful in 87 (98%) patients. At 1 month, 6% of patients had subacute stent thrombosis, 1% access-site complications and 3% major bleeding events. Stent thrombosis showed a univariate association with coumadin therapy (p = 0.009). Angiographic follow-up was obtained in 93% of 82 eligible patients. Restenosis rate was 32%, including 4% reocclusions. Through multiple logistic regression analysis, restenosis was independently associated with multiple stents (odds ratio-OR = 27.67, 95% confidence interval-CI = 4.25 to 79.95, p = 0.0008) and increasing values of occlusion length (OR = 1.23, 95% CI = 1.09 to 1.39, p = 0.001). Freedom from death, myocardial infarction or stented vessel revascularization was 87 and 72% at one and three years, respectively. CONCLUSIONS: Short- and long-term clinical and angiographic outcomes are favorable in patients undergoing Wiktor stent implantation for chronic coronary occlusion. Further technical refinements are needed to reduce restenosis rate in patients with long lesions and multiple stents. [less ▲]

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See detailTowards interbreed IBD fine mapping of the mh locus: double-muscling in the Asturiana de los Valles breed involves the same locus as in the Belgian Blue cattle breed.
Dunner, S.; Charlier, Carole ULg; Farnir, Frédéric ULg et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1997), 8(6), 430-5

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis ... [more ▼]

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis that this muscular hypertrophy involves the mh locus previously shown to cause double-muscling in the Belgian Blue cattle breed, pointing towards locus homogeneity of this trait across both breeds. Moreover, using a twopoint and multipoint maximum likelihood approach, we show that flanking microsatellite markers are in linkage disequilibrium with the mh locus in both breeds albeit with different alleles. Finally, we discuss how allelic homogeneity across breeds might be exploited to achieve efficient genetic fine-mapping of the mh locus. [less ▲]

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See detailAntisense galectin-3 alters thymidine incorporation in human MDA-MB435 breast cancer cells
van den Brûle, Frédéric; Bellahcene, Akeila ULg; Jackers, Pascale ULg et al

in International Journal of Oncology (1997), 11(2), 261-264

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See detailLes jeunes, leur activité physique et leurs perceptions de la santé, de la forme, des capacités athlétiques et de l’apparence
Ledent, Maryse; Cloes, Marc ULg; Piéron, Maurice

in Sport (1997), 159/160

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant ... [more ▼]

La perception de sa propre compétence exerce un rôle primordial dans la décision de pratiquer une activité physique. La continuité d'une pratique résulte notamment d'un niveau de compétence jugé suffisant. A partir de 12 ans, les jeunes sont capables d'évaluer leur compétence et de faire la distinction entre cette dernière et l'effort déployé dans la performance réalisée. ... [less ▲]

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See detailEnergy savings in methanol synthesis: Use of heat integration techniques and simulation tools.
Maréchal, François; Heyen, Georges ULg; Kalitventzeff, Boris ULg

in Computers & Chemical Engineering (1997), 21(Suppl. S), 511-516

Starting with a classical process for producing methanol using the reforming and synthesis steps, a combined approach applying simulation models and a new synthesis strategy, named Effect Modelling and ... [more ▼]

Starting with a classical process for producing methanol using the reforming and synthesis steps, a combined approach applying simulation models and a new synthesis strategy, named Effect Modelling and Optimisation (EMO), has been used to optimise the energy efficiency of the process. The method allows to identify different ways of improving the energy efficiency of the process. The modifications concern the synthesis reactor and the reforming reactor designs, the exploitation of the purge stream as fuel gas to satisfy the process requirement and its integration to a gas turbine system. The EMO approach allows to target the impact of a process modification at the global level of the energy cost of the process, including the combined production of heat and mechanical power in a gas turbine and the steam network. Starting with a classical methane conversion of 60% for the classical system, we identify solutions with up to 93% of the overall methane conversion when we transform the net mechanical power produced into methane savings at the country level. The interest of the approach is the possibility of computing the impact of the process modifications suggested by the analysis of the shape of the heat cascade on the overall energy balance of the plant without having to simulate in many details the steam and the heat exchanger network. [less ▲]

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See detailÀ propos de l'authenticité de la momie attribuée à Thoutmosis III (CG 61068)
Laboury, Dimitri ULg

in Göttinger Miszellen. Beiträge zur ägyptologischen Diskussion (1997), 156

L'article examine les différents arguments qui ont été avancés pour contester l'authenticité de la momie attribuée à Thoutmosis III (CG 61068). A l'issue de l'analyse, il apparaît qu'aucun ne résiste à la ... [more ▼]

L'article examine les différents arguments qui ont été avancés pour contester l'authenticité de la momie attribuée à Thoutmosis III (CG 61068). A l'issue de l'analyse, il apparaît qu'aucun ne résiste à la critique. En revanche, la découverte de cette momie dans un des cercueils originaux du roi, avec le linceul initial du souverain,- sans doute enroulé autour d'elle,- constitue un indice très sérieux en faveur de cette attribution. [less ▲]

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See detailSoluble and cell-associated transferrin receptor in lung cancer.
Dowlati, A.; Loo; Bury, Thierry ULg et al

in British Journal of Cancer (1997), 75(12), 1802-6

The expression of transferrin receptor (TfR) has been identified in many malignant tumours. In lung cancer, lymphoma and breast cancer, it has been shown that the expression of TfR correlates with tumour ... [more ▼]

The expression of transferrin receptor (TfR) has been identified in many malignant tumours. In lung cancer, lymphoma and breast cancer, it has been shown that the expression of TfR correlates with tumour differentiation, probably implying some prognostic value. A soluble form of TfR (sTfR) in human serum has been shown to be proportional to the number of cellular TfRs. Based on these data we examined the utility of measuring sTfR in the serum and bronchoalveolar lavage (BAL) fluid of patients with lung cancer (n = 32) and patients with chronic obstructive pulmonary disease (n = 22). BAL fluid was centrifuged to separate the supernatant from the cellular component. Cells were lysed in a detergent and cell-associated TfR was measured by enzyme-linked immunosorbent assay (ELISA) and expressed as ng 10(-6) cells in this cellular component. There was no difference in serum sTfR between the cancer and chronic obstructive pulmonary disease (COPD) groups. A higher level of cell-associated TfR was found in BAL of non-small-cell lung cancer patients than in COPD patients (P = 0.01). The calculated number of TfR molecules per cell in BAL correlated positively with the percentage of macrophages in BAL (P < 0.0001), suggesting that cell-associated TfR in BAL originates primarily from macrophages in this fluid. No correlation existed between BAL cell-associated TfR and tumour size, nodal status, the presence of metastases and serum sTfR. BAL cell-associated TfR was negatively correlated with BAL supernatant neuron-specific enolase (NSE) (P = 0.01). A combination of BAL supernatant NSE and cell-associated TfR detected lung cancer with a sensitivity of 91%, a specificity of 59% and positive and negative predictive values of 81% and 71% respectively. In conclusion, BAL cell-associated TfR may help in the differential diagnosis of lung cancer vs pneumonia. [less ▲]

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See detailEn mai élis qui te plaît
Durand, Pascal ULg

in Liège Université (1997), (été), 3

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See detailLes moyens de se prémunir contre la défaillance de ses cocontractants
Georges, Frédéric ULg

in Actualités du Droit (1997)

Cette contribution commentait l'impact de la réforme de 1997 du droit de l'insolvabilité sur les droits des créanciers

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See detailLa nature de l'acte juridique attesté par l'O. Mich. III 1098
Straus, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), LXXII(143), 128-129

O. Mich. III 1098 attests the delivery of a slave as a surety of a loan.

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See detailPrognostic factors in urothelial renal pelvis and ureter tumors: A multicenter Rare Cancer Network study
Ozsahin, Mahmut; Zouhair, Abderrahim; Villà, S. et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 3(2(supp)), 290

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See detailSm-Nd signature of modern and late Quaternary sediments from the northwest North Atlantic: Implications for deep current changes since the Last Glacial Maximum
Innocent, C.; Fagel, Nathalie ULg; Stevenson, Ross et al

in Earth & Planetary Science Letters (1997), 146(3-4), 607-625

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in ... [more ▼]

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in the surface sediments: (1) a radiogenic Nd typical of the Iceland volcanism; (2) a ''Pan-African'' Nd issued from eastern Greenland; (3) a ''Variscan'' Nd derived from the Arctic Ocean; (4) an old unradiogenic Nd related to the North American Shield, In the Iceland and Irminger basins, the major sources of Nd are the Variscan Nd derived from the Arctic Ocean and the Iceland Nd, except in the western Irminger Basin where the Pan-African Nd originating from eastern Greenland is dominant and labels sedimentary supplies linked to the Denmark Strait Overflow Water, Nd derived from Icelandic volcanism is never clearly dominant, even on the Reykjanes Ridge, and the Nd derived from the American Shield becomes dominant only in the Labrador Sea, Sediments lying in the pathway of the Western Boundary Undercurrent have Nd isotopic compositions which are shifted towards more radiogenic values indicating an input of material from the eastern basins, carried by this deep current. Late Quaternary sediments were cored from the southern Greenland Rise (core 90-013-013) and eastern Labrador Rise (Orphan Knell; core 91-045-094). In core 90-013-013, epsilon Nd values during the Last Glacial Maximum are as low as -20, but subsequently rose to -9 in the modern sediments, indicating that the sedimentary material during the Last Glacial Maximum was dominated by unradiogenic Nd from the North American Shield. This may be related to a lesser outflow of the Western Boundary Undercurrent, In core 91-045-094, located along the Labrador Current trajectory, a dominant supply of North American Shield Nd is recorded, perhaps originating at least partially from the Hudson Strait, The Sm-Nd data are compatible with smectite vs. illite studies at the same sites which suggest a continuous but more modest Western Boundary Undercurrent supply during Last Glacial Maximum. [less ▲]

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See detailLes pesticides: effets endocriniens et cancérogènes chez l'Homme
Charlier, Corinne ULg; Plomteux, Guy ULg

in Toxicorama (1997), IX

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See detailCharacterization of Clostridium perfringens isolates from goats.
Phukan, A.; Dutta, G.-N.; Daube, Georges ULg et al

in Indian Veterinary Journal (The) (1997), 74

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See detailThe yeast genome directory.
Goffeau, A.; Hilger, F.; Portetelle, Daniel ULg et al

in Nature (1997), 387(5),

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See detailUse Of Mycosphaerella Fijiensis Toxins For The Selection Of Banana Cultivars Resistant To Black Leaf Streak
Harelimana, Germain; Lepoivre, Philippe ULg; Jijakli, Haissam ULg et al

in Euphytica : International Journal of Plant Breeding (1997), 96(1), 125-128

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See detailEvaluation of pleural diseases with FDG-PET imaging: preliminary report.
Bury, Thierry ULg; Paulus, P; Dowlati, A et al

in Thorax (1997), 52(2), 187-9

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis ... [more ▼]

BACKGROUND: Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis of pleural disease was investigated in 25 patients. METHODS: PET was performed on each subject before invasive procedures were used to determine the aetiological diagnosis. The PET data were analysed by visual interpretation of coronal, sagittal, and transverse slices. RESULTS: Sixteen patients were found to have malignant pleural disease and nine had benign disease. All patients with histologically confirmed malignant disease showed FDG uptake within the pleural thickening which was intense in 14 cases and moderate in two. PET imaging showed the absence of FDG uptake and correctly categorised seven non-malignant lesions. Two patients with infectious pleural diseases showed a localised and moderate FDG uptake. CONCLUSION: Our preliminary results suggest that FDG-PET could be an effective tool for differentiating between benign and malignant pleural diseases. [less ▲]

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See detailPerspective in the treatment of insulin resistance.
Scheen, André ULg

in Human Reproduction (1997), 12 Suppl 1

Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including ... [more ▼]

Improving the action of insulin is a relatively new concept in therapy. It should, however, become more and more important because of the rapid expansion of the insulin resistance syndrome (including upper body adiposity, glucose intolerance, hypertension, dyslipidaemia, etc.) in industrialized countries and its dramatic consequences for public health. Insulin sensitivity can be improved by non-pharmacological means, essentially reduction of excessive body weight, promotion of regular physical activity and modification of dietary habits, as well as, possibly, cessation of smoking and correction of subclinical magnesium deficiency. Currently available pharmacological means mainly include the biguanide compound metformin and possibly anti-obesity agents, such as (d-) fenfluramine, fluoxetine and benfluorex. New compounds aiming at improving the action of insulin are in development, especially the thiazolidinedione derivatives (e.g. troglitazone), known as 'insulin sensitizers'. Treatment of insulin resistance may have important gynaecological applications, essentially in polycystic ovary syndrome and, possibly, after menopause. Hopefully, improving insulin sensitivity could ameliorate the cardiovascular prognosis of numerous individuals having some or all components of insulin resistance syndrome. [less ▲]

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See detailcompte rendu de : Philippe Dain, Mythographe du Vatican I. Traduction et commentaire
Rochette, Bruno ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1997), 10

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See detailHemodynamic effects of increasing PEEP during mechanical ventilation in anesthetized patients
LAMBERMONT, Bernard ULg; Ghuysen, Alexandre ULg; D'Orio, Vincenzo ULg et al

in American Journal of Respiratory & Critical Care Medicine (1997), 2

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See detailFormation of long-wavelength chlorophyllide (Chlide695) is required for the assembly of Photosystem II in etiolated barley leaves
Franck, Fabrice ULg; Eullaffroy, P.; Popovic, R.

in Photosynthesis Research (1997), 51(2), 107-118

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide ... [more ▼]

Chlorophyll(ide) spectroscopic properties and Photosystem II assembly, monitored by 77 K variable fluorescence, were studied in etiolated barley leaves as a function of the extent of protochlorophyllide photoreduction by a single millisecond light flash of different intensities. Variable fluorescence, measured 2 hours after the flash, was only detected when the extent of phototransformation was higher than a threshold value of 0.4. Its development paralleled the formation of a chlorophyll emission component at 685 nm, which itself derived from long-wavelength chlorophyllide with an emission maximum at 695 nm. At low flash intensities, short-wavelength chlorophyllide forms preferentially accumulated and no Photosystem II fluorescence was detected after 2 hours. Chlorophyllide esterification was independent of the extent of phototransformation. These results suggested that the formation of long-wavelength chlorophyllide was essential for further assembly of Photosystem II. This interpretation was strengthened by the observed inhibition of both long-wavelength chlorophyllide formation and of variable fluorescence development in leaves treated with 6-aminolevulinic acid or in untreated leaves subjected to repeated flashes of low intensity. [less ▲]

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See detailVaccinia virus immune evasion
Smith, G. L.; Symons, J. A.; Khanna, A. et al

in Immunological Reviews (1997), 159

Vaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include ... [more ▼]

Vaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include proteins which oppose apoptosis. Synthesise steroids, capture chemokines, counteract complement, interfere with interferon and intercept interleukins. This review provides an overview of such proteins, with an emphasis on work from our laboratory, and illustrates how the study of these proteins can increase our understanding of virus pathogenesis, the function of the immune system and how to make safer and more immunogenic poxvirus-based vaccines. [less ▲]

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See detailEstimation des dégâts de cervidés en pessière wallonne : Une application ciblée de l'inventaire régional
Rondeux, Jacques ULg; Lecomte, Hugues

in Forêt Wallonne (1997), (31), 6-9

Au sein des régions forestières comprises dans la zone d'extension du cerf (Cervus elaphus L.) en Wallonie, les dégâts dûs aux écorcements et aux frottures comptent parmi les tares les plus graves qui ... [more ▼]

Au sein des régions forestières comprises dans la zone d'extension du cerf (Cervus elaphus L.) en Wallonie, les dégâts dûs aux écorcements et aux frottures comptent parmi les tares les plus graves qui peuvent affecter un peuplement, qu'il s'agisse de son potentiel de régénération ou de la qualité du bois produit. Peu d'informations chiffrées relatives à ces dégâts existent à une échelle autre que celle de massifs ou de propriétés. La récente mise en oeuvre méthodologique de l'inventaire forestier wallon permanent basé sur un échantillonnage systématique a prévu, à l'instar d'autres inventaires réalisés en Europe, la récolte d'informations non seulement relatives au matériel ligneux et à son évolution au cours du temps mais aussi à d'autres applications. L'étude qui suit propose une méthode d'investigation des dégâts de cervidés sur l'ensemble des pessières de la forêt wallonne. Elle ne vise en aucune manière à porter un jugement sur l'équilibre "forêt-gibier" mais son objectif est, dans une large mesure, de montrer comment il est possible de préciser la nature et l'importance des dégâts encourus et de proposer ainsi une alternative aux approximations visuelles sommaires fournies à des échelles locales et non extrapolables, sous peine de devoir recourir à des hypothèses irréalistes. Après avoir défini l'opportunité même de l'étude, nous rappellerons brièvement quelques aspects méthodologiques de l'inventaire, nous en envisagerons ensuite le type de données récoltées en matière de dégâts occasionnés aux arbres, ainsi que les modalités de traitement et d'exploitation de celles-ci. Nous proposerons enfin une application concrète de la technique d'investigation aux pessières de la Région wallonne, avant de tirer quelques conclusions générales. [less ▲]

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See detailElementverteilung in einem moorprofil (Präboreal bis subatlantikum) im Tal der Helle/Hill (Hohes Venn, Belgien)
Gaida, R.; Olbrechts, S.; Hindryckx, Marie-Noëlle ULg et al

in Geoökodynamik (1997), XVIII(2/3), 79-90

This investigation was on the distribution of some elements (Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn) in a groundwater bog in the Helle/Hill valley in the Hohes Venn, Belgium. The thickness of the ... [more ▼]

This investigation was on the distribution of some elements (Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn) in a groundwater bog in the Helle/Hill valley in the Hohes Venn, Belgium. The thickness of the deposit is 155 cm. This bog has developed since the Pre Boreal period. The distribution in the lower part of the bog profile is very strongly influenced by water from the adjacent slope which is characterised by a high content of different metals. This resulted in a significant amount of Fe, Ni and Zn and to a lesser degree of Cu and Cd. The metals stem from ore which originated from the nearby Hill valley tonalite. The weathering of the sulphidic ore created sulphuric acid which is responsible for the low pH values of the peat samples. Not only the influence of the local geology and mineralogy is discussed, but also the behaviour of different plants with respect to element uptake and accumulation. Atmospheric input also has an influence, especially on the distribution of the elements in the upper part of the profile. [less ▲]

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See detailInfluence of whole milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats
Hornick, Jean-Luc ULg; Clinquart, Antoine ULg; Van Eenaeme, Christian ULg et al

in Livestock Production Science (1997), 48

Influence of milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats. The use of milk as component ... [more ▼]

Influence of milk in diet of growing fattening Belgian Blue bulls on animal performances and on fatty acid composition in subcutaneous, intermuscular and intramuscular fats. The use of milk as component of a fattening diet for bulls was studied in an experiment carried-out over 2 years with Belgian Blue bulls. The animals weighed 305 kg at the beginning of the experiment. In all, 15 bulls were given a control concentrate fattening diet (control group, CG), while 11 others were fed concentrate plus 6.5 to 11 1 whole milk per day according to weight or age (milk group, MG). The fattening period lasted for 174 and 181 d respectively in groups CG and MG. The MG-group had a higher killing-out percentage (P < 0.01) and the meat was characterized by a lower b* value and a lower dry matter content (P < 0.1). Whole milk in the diet increased the proportion of shorter chain and saturated fatty acids in fat (P < 0.001) and reduced the proportion of mono- and polyunsaturated acids (P < 0.05; P < 0.1). The extent of the changes were larger in subcutaneous and intermuscular fats than in intramuscular fat. [less ▲]

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See detailIdentification des vaches laitières traitées à la somatotropine bovine
Scippo, Marie-Louise ULg; Degand, Guy ULg; Duyckaerts, Anne et al

in Annales de Médecine Vétérinaire (1997), 141(5), 381-390

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See detailFibres alimentaires chez le chien : VII. Intérêt dans le traitement diététique de l'animal obèse
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with ... [more ▼]

The present review deals with obesity in the dog, Definition, incidence, assessment, etiology and detrimental effects of obesity are firstly presented. In a second part, the treatment is discussed, with particular emphasis on the incorporation of large quantities of dietary fibres in low-energy specific purpose food. At present time, no conclusions can be drawn from published studies [less ▲]

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See detailEntre Babil et Babel
Durand, Pascal ULg

in Liège Université (1997), (Automne), 15

Compte rendu de J.-A. Rondal et J.-P. Thibaut, Psychologie de l'enfant et de l'adolescent, Bruxelles, Labor, 1997

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See detailTwo centuries of vaccination
Vanderplasschen, Alain ULg; Smith, G. L.

in Annales de Médecine Vétérinaire (1997), 141

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See detailLe rôle de l'officier de l'état civil requis de célébrer un mariage présumé simulé
Paris, Catherine ULg

in Revue Trimestrielle de Droit Familial (1997)

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See detailComment j'explore ... le syndrome d'insulinoresistance grace a ses marqueurs biologiques.
Luyckx, Françoise ULg; Scheen, André ULg; Gielen, Jean-Louis ULg et al

in Revue Médicale de Liège (1997), 52(10), 686-91

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See detailUsefulness of 18fdg Positron Emission Tomography in Detection and Follow-up of Digestive Cancers
Paulus, P.; Hustinx, Roland ULg; Daenen, Frédéric ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(4, Oct-Dec), 278-80

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow ... [more ▼]

PET is a diagnostic method that creates high resolution, 3 dimensional tomographic images of the distribution of positron emitting radionuclides in the human body. Recent technological developments allow the use of whole-body PET devices in clinical oncology. 18FDG is a glucose analog transported and competitively used with glucose reflecting the increased glucose metabolism into malignant cells. Differential diagnosis between chronic pancreatitis and pancreatic cancer is already a well-documented indication. For initial staging of gastro-esophageal and colorectal tumours, results are preliminary but the clinical impact seems to be rather limited. At present, the major indication of FDG-PET is the detection and staging of colorectal cancer recurrences. FDG-PET allows the differentiation between scared tissue and tumour when structural imaging is often confusing. In the same time, the whole-body imaging capability provides unique information that can modify loco-regional and liver staging. Overall, FDG-PET affects the clinical management of 30 to 40% of these patients. Quantitative assessment of therapeutic response to chemotherapy regimen appears to be one of the most promising applications of FDG-PET. Since the most effective therapy of colorectal cancer are often surgical, the role of chemotherapy in colorectal cancer remains limited to adjuvant therapy and in advanced disease. However, FDG-PET could be of great value in assessing the response of oesophageal carcinomas to chemo-radio therapy, before surgery. In our experience, FDG-PET appears to be the first line diagnostic method in the detection and staging of colorectal recurrence and differential diagnosis of pancreatic tumour versus chronic pancreatitis. [less ▲]

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See detailThe role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids.
El Ouahabi, A.; Thiry, Marc ULg; Pector, V. et al

in FEBS Letters (1997), 414(2), 187-92

We used a 32P-labeled pCMV-CAT plasmid DNA to estimate the DNA uptake efficiency and unlabeled pCMV-CAT plasmid DNA to quantify the CAT activity after transfection of COS cells using each of the three ... [more ▼]

We used a 32P-labeled pCMV-CAT plasmid DNA to estimate the DNA uptake efficiency and unlabeled pCMV-CAT plasmid DNA to quantify the CAT activity after transfection of COS cells using each of the three following cationic compounds: [1] vectamidine (3-tetradecylamino-N-tert-butyl-N'-tetradecylpropionamidine, and previously described as diC14-amidine [1]), [2] lipofectin (a 1:1 mixture of N-(1-2,3-dioleyloxypropyl)-N,N,N-triethylammonium (DOTMA) and dioleylphosphatidylethanolamine (DOPE)), and [3] DMRIE-C (a 1:1 mixture of N-[1-(2,3-dimyristyloxy)propyl]-N,N-dimethyl-N-(2-hydroxyethyl) ammonium bromide (DMRIE) and cholesterol). Surprisingly, a high CAT activity was observed with vectamidine although the DNA uptake efficiency was lower as compared to lipofectin and DMRIE-C. Transmission electron microscopy (TEM) revealed endocytosis as the major pathway of DNA-cationic lipid complex entry into COS cells for the three cationic lipids. However, the endosomal membrane in contact with complexes containing vectamidine or DMRIE-C often exhibited a disrupted morphology. This disruption of endosomes was much less frequently observed with the DNA-lipofectin complexes. This comparison of the three compounds demonstrate that efficient transfection mediated by cationic lipids is not only correlated to their percentage of uptake but also to their ability to destabilize and escape from endosomes. [less ▲]

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See detailThe meaning of formal: from weak to strong formal methods
Wolper, Pierre ULg

in International Journal on Software Tools for Technology Transfer (1997), 1(1-2), 6--8

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable ... [more ▼]

This short note reflects on what makes formal methods "formal". It concludes that there are weak and strong ways of being formal, the latter being linked to the formality of the method being exploitable, and exploited, in software tools. [less ▲]

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See detailRelationships of growth hormone gene and milk protein polymorphisms to milk production traits in Simmental cattle
Falaki, M.; Prandi, A.; Corradini, C. et al

in Journal of Dairy Research (1997), 64(1), 47-56

The importance of milk proteins and the positive effect of administration of growth hormone (GH) on milk production, and the presence in some dairy cattle lines of greater GH concentrations prompted us to ... [more ▼]

The importance of milk proteins and the positive effect of administration of growth hormone (GH) on milk production, and the presence in some dairy cattle lines of greater GH concentrations prompted us to examine the presence of restriction fragment length polymorphism at the GH gene using the restriction enzyme TaqI and to investigate associations between this polymorphism in Simmental cows and bulls, as well as milk protein variants in Simmental cows, and milk production traits. Blood and milk were sampled from 279 Italian Simmental cows and semen was collected from 148 bulls of the same breed. Two fragment bands, denoted A and B, of 6200 and 5200 bp respectively, were examined and three patterns, AA, AB and BB, were found in both animal samples. All variants previously reported in other studies, for kappa, beta, and alpha(s1)-caseins, and beta-lactoglobulin, were found in the cows' samples. For the cows' samples, a BLUP (Best Linear Unbiased Predictor) analysis of results was performed using a REML (Restricted Maximum Likelihood) program and known heritabilities, whereas for bulls we have performed a General Linear Model analysis. The effect of GH gene polymorphism, using TaqI restriction enzyme, on milk production traits was not significant, but bulls of BB pattern had a higher breeding value for milk yield than AA bulls (P < 0.05). For the kappa-casein genotypic effects, cows of AB genotype gave milli with 1.53+/-0.70 g/kg less fat than cows of AA genotype. In addition, breeding values for milk protein content were significantly higher in BB bulls, with 0.87+/-0.32 and 0.71+/-0.34 g/kg more milk protein than AA and AB bulls respectively. Thus, our results revealed a GH gene polymorphism and indicated significant effects of milk protein polymorphisms on milk production traits in the Italian Simmental breed. [less ▲]

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See detailLattice dynamics and ferroelectric instability of barium titanate
Ghosez, Philippe ULg; Gonze, X.; Michenaud, J. P.

in Ferroelectrics (1997), 194

Using first-principles calculations, we investigate the lattice dynamics of cubic and rhombohedral BaTiO3 and rye discuss the origin of the structural instability of this ferroelectric material. First, we ... [more ▼]

Using first-principles calculations, we investigate the lattice dynamics of cubic and rhombohedral BaTiO3 and rye discuss the origin of the structural instability of this ferroelectric material. First, we report results on the Born effective charges and the dielectric tensor and we emphasize the important reduction of these quantities in the ferroelectric phase, Then, the phonon frequencies at the Gamma point are calculated. We point out the similarity of theoretical eigenvectors in the cubic and rhombohedral phases. We examine the interaction of the vibration modes with the electric field and in particular the giant LO-TO splitting of the ferroelectric mode. Finally, separating the dipole-dipole interaction from the remaining short-range forces, we quantify the balance of forces leading to an unstable phonon in the cubic phase and we demonstrate its sensitivity to tiny effective charge changes. Within our decomposition, the stabilization of the unstable mode in the rhombohedral phase is produced by a reduction of the Born effective charges, while its stabilization under isotropic pressure is associated with a modification of the short-range forces. [less ▲]

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See detailJungermannia paroica (Schiffn.) Grolle in the Vosges, new to France
Vanderpoorten, Alain ULg; Sotiaux, André ULg

in Journal of Bryology (1997), 19

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See detailIA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry.
Gorus, F. K.; Goubert, P.; Semakula, C. et al

in Diabetologia (1997), 40(1), 95-9

IA-2 has been identified as an autoantigen that is recognized by immunoglobulins from insulin-dependent diabetic (IDDM) patients. Using a liquid phase radiobinding assay, we performed an IA-2-autoantibody ... [more ▼]

IA-2 has been identified as an autoantigen that is recognized by immunoglobulins from insulin-dependent diabetic (IDDM) patients. Using a liquid phase radiobinding assay, we performed an IA-2-autoantibody (IA-2-Ab) assay in 474 IDDM patients and 482 non-diabetic control subjects aged 0-3 years. IA-2-Ab were detected in 58% of the patients and 0.8% of control subjects. Their prevalence in patients was lower than that of islet cell autoantibodies (ICA; 73%) or glutamic acid decarboxylase (M(r) 65 kDa)-autoantibodies (GAD65-Ab; 82%) but higher than that of insulin autoantibodies (IAA; 42%). IA-2-Ab were more frequent in patients under age 20 years (70%) than between 20 and 40 years (45%; p < 0.001). In the whole IDDM group, 92% of patients were positive for at least one of the three molecular assays, which is higher than the positivity for the ICA assay (73%). Only 1% was negative in the molecular assays and positive in the ICA assay. IA-2-Ab levels were positively correlated with ICA titres (p < 0.001) and HLA DQ A1*0301-DQ B1*0.02 (p < 0.003) by multivariate analysis. In a group of 481 non-diabetic siblings (age 0-39 years) of IDDM patients only 7 were IA-2-Ab positive (1.5%). All seven were under age 20 years and positive for at least two other autoantibodies and for DQ A1*0301-DQB1*0302. Four of these seven developed IDDM during the 6-70-month follow-up period. The positive predictive value of IA-2-Ab (57%) was higher than that of ICA, GAD65-Ab or IAA alone, or in combination (< or = 20%) but these calculations are restricted by the relatively short observation period and the small number of cases. The only IA-2-Ab-negative case of pre-diabetes was also negative for IAA and GAD65-Ab, while it was strongly positive for ICA. In conclusion, IA-2-Ab show a high diagnostic specificity for IDDM and are predictive markers of impending diabetes in siblings of patients. In combination with other molecular antibody assays they may replace ICA testing in future. Our data also indicate that other autoantibodies than IA-2-Ab, GAD65-Ab and IAA contribute to ICA. [less ▲]

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See detailL'homeopathie peut-elle trouver sa legitimite dans les resultats "positifs" d'une meta-analyse?
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(11), 694-7

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See detail67-kD laminin receptor expression correlates with worse prognostic indicators in non-small cell lung carcinomas.
Fontanini, G.; Vignati, S.; Chine, S. et al

in Clinical Cancer Research : An Official Journal of the American Association for Cancer Research (1997), 3(2), 227-31

Tumor samples obtained from 72 patients resected for non-small cell lung cancer were stained immunohistochemically using an immunoperoxidase method and the MLuC5 monoclonal antibody specific for the 67 ... [more ▼]

Tumor samples obtained from 72 patients resected for non-small cell lung cancer were stained immunohistochemically using an immunoperoxidase method and the MLuC5 monoclonal antibody specific for the 67-kDa laminin receptor. Sixty-one of 72 patients (84.7%) displayed a MLuC5-positive reaction, which was usually localized in both the inner surface of the plasmatic membranes and the cytoplasm of neoplastic cells. When we compared the laminin receptor expression with clinicopathological and biological parameters such as histotype, grading, T status, N status, ploidy, proliferative activity, vessel invasion, and p53 protein accumulation, the following results were observed: (a) the mean expression of the receptor was higher in the group of patients with metastatic nodal involvement than in those with uninvolved lymph nodes (P = 0.02); (b) a high Ki-67 score (>13% of positive cells) was observed in tumors with a higher mean value of laminin receptor (P = 0.004); (c) the tumors harboring neoplastic emboli in their vessels showed a higher laminin receptor immunoreactivity (P = 0.02); and (d) a borderline association was found between the high mean value of laminin receptor immunopositivity and p53 accumulation in neoplastic cell nuclei (P = 0.05). Our observations indicate that detection of high tissue levels of 67-kDa laminin receptor is associated with an invasive phenotype in non-small cell lung cancer and may provide further information in the biological characterization of this type of cancer. [less ▲]

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See detailLa controverse a propos de la decouverte de l'insuline. L'histoire vue sous l'angle de la philatelie.
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(12), 756-9

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See detailDilatometric and calorimetric study of the graphitisation of high chromium cast iron
Terziev, L.; Lecomte-Beckers, Jacqueline ULg; Bojinov, V. et al

in Journal de Chimie Physique et de Physico-Chimie Biologique (1997), 94[5]

Cette étude est consacrée à la formation du graphite dans des fontes à haute teneur en chrome (8%) et spécialement à la détermination des conditions de formation de graphite secondaire par des traitements ... [more ▼]

Cette étude est consacrée à la formation du graphite dans des fontes à haute teneur en chrome (8%) et spécialement à la détermination des conditions de formation de graphite secondaire par des traitements thermiques adaptés. La solidification de la fonte étudiée a été examinée par analyse thermique différentielle (ATD). Les effets d'un traitement à haute température ont été examinés à la fois par calorimétrie et dilatomètre différentielle. Le graphite primaire se forme vers 950°C. Le graphite secondaire précipite sur le graphite primaire lors du traitement de déstabilisation de l'austénite à haute température. La forme et la quantité de graphite secondaire dépendent de la température de traitement. [less ▲]

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See detailPharma-clinics. Le medicament du mois. Le Legalon (silymarine).
Luyckx, Françoise ULg; Scheen, André ULg

in Revue Médicale de Liège (1997), 52(12), 792-6

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See detailComment j'explore ... Une maladie de Basedow: de la clinique classique au diagnostic radio-immunologique.
Scheen, André ULg

in Revue Médicale de Liège (1997), 52(12), 788-91

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See detailStability margins of nonlinear receding horizon control via inverse optimality
Magni, L.; Sepulchre, Rodolphe ULg

in Systems & Control Letters (1997), 32(4), 241-245

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result ... [more ▼]

Using the nonlinear analog of the Fake Riccati equation developed for linear systems, we derive an inverse optimality result for several receding horizon control schemes. This inverse optimality result unifies stability proofs and shows that receding horizon control possesses the stability margins of optimal control laws. [less ▲]

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See detailA global model of the biosphere : validation and applications to present and past climatic conditions
François, Louis ULg; Gérard, Jean-Claude ULg; Nemry, Bernard et al

in Sciences Géologiques. Bulletin (1997), 50(1-4), 89-107

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See detailLes rideaux de Magritte
Steinmetz, Rudy ULg

in Degrés : Revue de Synthèses à Orientation Sémiologique (1997)

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See detailThe Nucleotide Sequence Of Saccharomyces Cerevisiae Chromosome Vii
Tettelin, H.; Carbone, Mla.; Albermann, K. et al

in Nature (1997), 387(6632),

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See detailEffect of n-3 fatty acids in Eurasian perch broodstock diet on egg fatty acid composition and larva stress resistance.
Abi-Ayad, Amine; Mélard, Charles ULg; Kestemont, Patrick

in Aquaculture International (1997), 5

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See detailMeasurements of the ground state ionization energy and wavelengths for the 1snp1P1 - 1s2 1S0(n=4-10) lines of O VII
Bartnik, A.; Biémont, Emile ULg; Dyakin, V. M. et al

in Journal of Physics : B Atomic Molecular & Optical Physics (1997), 30

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See detailField observations of the spawning behaviour of European grayling
Darchambeau, François ULg; Poncin, Pascal ULg

in Journal of Fish Biology (1997), 51(5), 1066-1068

During observations of the River Ourthe, Belgium, 70 spawning attempts were recorded during the reproductive period of the European grayling. Thirty-six per sent of the spawning attempts proceeded to ... [more ▼]

During observations of the River Ourthe, Belgium, 70 spawning attempts were recorded during the reproductive period of the European grayling. Thirty-six per sent of the spawning attempts proceeded to completion, while interference by another male may explain some of the incomplete acts. Sneaking behaviour was observed and one spawning act included two males and one female. (C) 1997 The Fisheries Society of the British Isles. [less ▲]

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See detailLe visage de l'Autre ou la conscience du regard
Mélon, Marc-Emmanuel ULg

in Revue belge du cinéma (1997), 41

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See detailBulletin bibliographique de la Société Rencesvals, 1996-1997
Horrent, Jacques ULg; Henrard, Nadine ULg

in Bulletin bibliographique de la Société Rencesvals (1997), (28), 189

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See detailLuteinizing hormone increases the abundance of various transcripts, independently of the androgens, in the rat prostate.
Reiter, E.; Poncin, Joseph ULg; Hennuy, Benoît ULg et al

in Biochemical and Biophysical Research Communications (1997), 233(1), 108-12

Differential display analysis was carried out to find, in the rat prostate, genes that could be regulated by Luteinizing Hormone (LH), independently of the androgens. Hypophysectomized and castrated adult ... [more ▼]

Differential display analysis was carried out to find, in the rat prostate, genes that could be regulated by Luteinizing Hormone (LH), independently of the androgens. Hypophysectomized and castrated adult rats were treated with either LH, testosterone or saline. Regulated discrete bands have been eluted and reamplified. After Northern blotting, the levels of mRNA corresponding to 8 PCR fragments were significantly increased by LH treatment. None of these inserts were found to be induced by testosterone. One insert was subcloned, sequenced and identified as the ribosomial protein S 23. A competitive RT-PCR assay was carried out on the full length S 23 cDNA and confirmed that its mRNA levels were stimulated by LH but not by testosterone. These results strongly suggest that the LH membrane receptor, previously shown to be expressed in the rat prostate, has a physiological significance in this organ. Moreover, it appears that the effect of LH on the rat prostate are independent of the androgens. [less ▲]

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See detailRésumé des communications et livret guide des excursions
Petit, François ULg; Wastiaux, Cécile; Assani, Ali Arkamose et al

in Journées hydrologiques françaises (Commission des Hydrosystèmes fluviaux) Journées de terrain organisées en Ardenne et dans les Hautes fagnes (1997)

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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