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See detailLa maladie de Buerger: aspects cliniques et pronostiques
VAN DAMME, Hendrik ULg; Deprez, E.; DEFRAIGNE, Jean ULg et al

in Revue Médicale de Liège (1997), 52(10), 675-82

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See detailHepatocyte transplantation prolongs survival and prevent development of brain edema in pigs with ischemic liver failure
Arkadopoulos, N.; Chen, S.; Khalili, T. et al

in Surgical Forum (1997), 44

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See detailRelations entre les conditions d'habitat et la pathologie en production de viande bovine
Nicks, Baudouin ULg

in Aspects de la conception des bâtiments pour les bovins à viande (1997)

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See detailLa cavernostomie: une ancienne technique parfois efficace dans le traitement des abcès pulmonaires
Defraigne, Jean-Olivier ULg; Siquet, J.; Limet, Raymond ULg

in Revue Médicale de Liège (1997), 52(7), 498-501

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See detailMemory kernels and effective Hamiltonians from time dependent methods. I. Predissociation with a curve crossing
Desouter, Michèle ULg; Liévin, Jacques

in Journal of Chemical Physics (1997), 107

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See detailLong term follow-up of patients with acute myelogenous leukemia who received the daunorubicin, vincristine, and cytosine arabinoside regimen.
Beguin, Yves ULg; Sautois, Brieuc ULg; Forget, Patricia ULg et al

in Cancer (1997), 79(7), 1351-4

BACKGROUND: In 1985, the authors published a study of acute myelogenous leukemia (AML) patients treated with a chemotherapeutic regimen that was then considered intensive. Ten years later, the authors ... [more ▼]

BACKGROUND: In 1985, the authors published a study of acute myelogenous leukemia (AML) patients treated with a chemotherapeutic regimen that was then considered intensive. Ten years later, the authors reanalyzed the same cohort to determine whether the very promising actuarial results observed at 5 years held after longer follow-up. METHODS: Between 1977 and 1982, 61 patients with AML were treated with a protocol consisting of daunorubicin, vincristine, and cytosine arabinoside induction followed by consolidation and maintenance for a total of 2 years. The complete remission (CR) rate was 66%, 84% in males versus 47% in females (P < 0.005). At the time of the first analysis in 1984, the overall survival (OS) was 17%, the projected 5-year continuous CR rate (CCR) 32%, and the disease free survival (DFS) rate 29%, with the best results observed for males and for patients ages 40-60 years (P < 0.05). RESULTS: When the data were reanalyzed 11 years later in 1995, the results were 14% OS, 23% CCR, and 16% DFS at 5 years. However, these figures dropped to 8%, 18%, and 11% at 10 years and to 8%, 12%, and 7% at 15 years, respectively. Among the 40 CR patients, 31 relapsed (up to 13 years after CR), and all died within 1.6 years after relapse. Nine patients were in CCR: 4 died of unrelated causes (suicide, alcoholic cirrhosis, acute peritonitis, or bladder carcinoma), 1 was lost to follow-up after 11 years, 2 were alive and well at 17 years at last follow-up, and 2 were transplanted in first CR and were doing well at 13 and 14 years at last follow-up. The survival advantage for males over females persisted (P = 0.0197), but the advantage for patients age 40-60 years did not hold. CONCLUSIONS: These long term data indicate that actuarial analysis at 5 years may overestimate the cure rate of AML patients because a number of late relapses do occur. However, the picture is blurred by the incidence of death not related to leukemia or its treatment; and when these patients were censored at the time of death, 17% of CR patients were still projected to be alive and free of leukemia after 17 years. [less ▲]

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See detailTerm analysis and Hyperfine Structure in Neutral Vanadium
Palmeri, P.; Biémont, Emile ULg; Quinet, P. et al

in Physica Scripta (1997), 55

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See detailGlucose metabolism during bovine preimplantation development: analysis of gene expression in single oocytes and embryos.
Lequarré, Anne-Sophie ULg; Grisart, B.; Schuurbiers, N. et al

in Molecular Reproduction and Development (1997), 48(2), 216-26

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose ... [more ▼]

Glucose metabolism of the bovine embryo is low during the first cleavages and increases sharply after the major resumption of the genome (8-16 cells). The mRNA level for genes involved in glucose metabolism was tested by RT-PCR on individual oocytes and embryos at different stages of development. These genes were: glucose transport GLUT-1, hexokinase (HK), glucose-6-phosphatase-dehydrogenase (G6PDH), and glucose-phosphate-isomerase (GPI); actin was used as a reference transcript. RT-PCR results revealed three types of oocytes or embryos: positive with a PCR signal for each transcript considered, nul with no signal for any transcript, and heterogeneous with a PCR signal for some transcripts and none for others. The number of nul and heterogeneous samples was higher for slow than for fast-cleaving embryos (81% vs. 36%), and the proportion of positive embryos increased significantly at the 16-cell and morula stages (P < 0.002), suggesting a correlation between mRNA content and developmental capacity. In positive embryos, GLUT-1 level was reduced by half during maturation and fertilization. Actin and hexokinase mRNA levels decreased during the first cleavages, but significantly increased at the 16-cell and morula stages, respectively. GPI transcript remained stable throughout development, whereas there was a significant rise for G6PDH at the 4-cell stage, perhaps due to a polyadenylation process. Finally, the absence or decrease in intensity of several transcripts at the blastocyst stage suggests suboptimal culture conditions. [less ▲]

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See detailOrigine des produits animaux et empreinte génétique
Portetelle, Daniel ULg; Mortiaux, Frédéric; Burny, Arsène et al

in Agricontact (1997), 294

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See detailMolecular dissection of the insulin-like growth factor axis in the human thymus
Geenen, Vincent ULg; Kecha, Ouafae; Achour, Imane et al

in Diabetologia (1997), 40

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See detailIncorporation of rapeseed meal extracted by pressure in a diet for growing fattening bulls .1. Intake, digestibility and fermentation in the rumen
Mayombo, A. P.; Baldwin, Paule ULg; Wathelet, Jean-Paul ULg et al

in Annales de Zootechnie (1997), 46(1), 57-70

Intake, digestibility, degradation kinetic and fermentation were studied with bulls offered fattening diets with four different incorporation rates of rapeseed meal obtained by pressure; the ether extract ... [more ▼]

Intake, digestibility, degradation kinetic and fermentation were studied with bulls offered fattening diets with four different incorporation rates of rapeseed meal obtained by pressure; the ether extract content was 8.6% and the glucosinolate content 17,6 mu molg. The control diet was made of sugar beet pulp, cereals, soya bean meal and linseed meal. In the three other diets, nitrogen from rapeseed meal provided 33, 66 or 100% of nitrogen from soya bean meal or linseed meal. The intakes of the control diet were 94.3 +/- 7.3 g/kg metabolic body weight. Intakes were maintained high in the diet with 33, 66 or 100% of protein from rapeseed meal at 93.5 +/- 7.7; 93.0 +/- 5.0 and 93.5 +/- 7.7 g/kg, respectively. The apparent digestibility of rapeseed meal in the ration containing only rapeseed meal was high at 74.9 +/- 1.9% for dry matter, 76.5 +/- 2.1% for organic matter, 69.9 +/- 3.9% for nitrogen, 59.1 +/- 4.8% for ADF and 74.6 +/- 6.9% for ether extract. Dry matter of rapeseed meal was less degradable (57.8 +/- 5.0%) than that of soya bean meal (65.5 +/- 2.6%) or of linseed meal (61.6 +/- 4.2%) but was not as well protected than that of protected soya bean meal (43.6 +/- 2.6%) (P < 0.001). Similar trends were observed for the degradability of nitrogen (P < 0.001). Ether extract of rapeseed meal was more degradable than that of linseed meal (P < 0.001). There were no significant effects of the incorporation rate of rapeseed meal on the pH in the rumen. The fermentations were mainly of the acetate type with usual concentrations of propionate, butyrate, total volatile fatty acids, glucose or alpha amino nitrogen. Ammonia concentration was higher with the control diet and lower with the diet with 100% of protein from rapeseed meal. Fatty acids of rapeseed meal were more protected against saturation by the rumen microorganisms than in linseed meal. [less ▲]

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See detailAllozyme diversity and genetic structure in South - Western populations of Heather, Calluna vulgaris (L.) Hull
Mahy, Grégory ULg; Vekemans, Xavier; Jacquemart, Anne Laure et al

in New Phytologist (1997), 137

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See detailAspects économiques du financement des communes
Jurion, Bernard ULg

in Revue de Droit Communal (1997)

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See detailPresbyphonia voice differencies between the secties in the elderly. comparison by maximum phonation time, phonation quotient and spectral analysis
Morsomme, Dominique ULg; Jamart, Jacques; Boucquey, Donatienne et al

in Logopedics, Phoniatrics, Vocology (1997), 22

This study of 40 elderly subjects (30 women and 10 men) between the ages of 70 to 90, attempts to qualify and quantify their voices and to compare the results with a young population and to establish any ... [more ▼]

This study of 40 elderly subjects (30 women and 10 men) between the ages of 70 to 90, attempts to qualify and quantify their voices and to compare the results with a young population and to establish any differences between the two sexes. The measurements concerned the Vital Capacity (VC), the Maximum Phonation Time (MPT) and the Phonation Quotient (PQ). The equivalent values for a young population were compiled from the literature. Spectral voice analysis was also included in the study. The mean speaking fundamental frequency (Fo) of the voice changes with age; it increases in men and decreases in women (158 Hz in elderly men vs a normal value of 120 Hz; 205 Hz in elderly women vs a normal value of 225 Hz). Ageing influences the vital capacity to the advantage of men (median VC = 2.61 vs 1.61 in elderly men and women, respectively). For sustaining a vowel a, the Maximum Phonation Time (MPT) is significantly better in elderly men (median MPT = 16 sec in elderly men and 12 sec for women). Phonation Quotient does not differ significantly between sexes (median PQ = 153 ml/sec in elderly men and 152 ml/sec in elderly women). Although, the physical capacity of elderly women decreases, their vocal output remains very good when compared to young women. In elderly men, however, there is a phonation quotient decrease of 25 per cent compared to young men. [less ▲]

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See detailEnantioseparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using mixtures of anionic and uncharged beta-cyclodextrins as chiral additives.
Fillet, Marianne ULg; Hubert, Philippe ULg; Crommen, Jacques ULg

in Electrophoresis (1997), 18(6), 1013-8

Nine nonsteroidal anti-inflammatory drugs (NSAIDs) were enantioseparated by capillary electrophoresis using an anionic cyclodextrin derivative (sulfobutyl ether beta-cyclodextrin or carboxymethyl-beta ... [more ▼]

Nine nonsteroidal anti-inflammatory drugs (NSAIDs) were enantioseparated by capillary electrophoresis using an anionic cyclodextrin derivative (sulfobutyl ether beta-cyclodextrin or carboxymethyl-beta-cyclodextrin) in combination with a neutral cyclodextrin as chiral additives to a pH 3 phosphoric acid-triethanolamine buffer. In the presence of a negatively charged cyclodextrin, the analytes were given an appropriate mobility but relatively low enantioselectivities were generally obtained when such a cyclodextrin was the only selector added to the buffer. The addition of an uncharged cyclodextrin, such as the native beta-cyclodextrin or one of its derivatives (dimethyl-, trimethyl- and hydroxypropyl-beta-cyclodextrin), to this kind of buffer containing an anionic cyclodextrin, was found to give rise to considerable improvement in chiral resolution for all compounds studied. Resolution and analysis time were optimized by varying the nature and concentration of the two cyclodextrins. The best compromise was usually achieved by the simultaneous addition of sulfobutyl ether beta-cyclodextrin and trimethyl-beta-cyclodextrin. Under optimum conditions, the enantiomers of all NSAIDs examined could be completely separated (most often with resolution values higher than 5) in short analysis times (generally lower than 15 min). [less ▲]

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See detailCharacterization of non pigmented B16 melanoma cell-derived cytotoxic factors.
Siwek, B.; De Pauw-Gillet, Marie-Claire ULg; Quetin-Leclercq, J. et al

in Chemico-Biological Interactions (1997), 103(1), 59-73

We analyzed and tried to characterize substance(s) responsible for cytotoxic activities detected in culture media conditioned by non pigmented B16 melanoma cells (NPB16). The different cytological tests ... [more ▼]

We analyzed and tried to characterize substance(s) responsible for cytotoxic activities detected in culture media conditioned by non pigmented B16 melanoma cells (NPB16). The different cytological tests used showed that ultrafiltrated conditioned media (CM U1 fraction) contained several cytotoxic factors with a Mw lower than 1000 Da. These factors seemed to act either directly or indirectly on cell membranes, mitochondria, on the cell cycle and on protein and DNA synthesis. A cytotoxic activity could be found even after high dilution of CM U1. These cytotoxic factors were rapidly released by B16 cells in culture, independently of cell confluence. Their activities in the treated cells were also very fast and the cytotoxic effects were irreversible after only a few hours of treatment. These factors were not intermediate products during melanogenesis, neither polyamines, nor proteases. At least one of them seemed to be a small acidic and basic stable peptide without disulfide bounds but not heat stable. The synthesis of at least one of these cytotoxic factors was inhibited by cycloheximide and the cytotoxic activity was partially destroyed by pronase and trypsin, but not by pepsin. The cytotoxicity was not modified by copper complexants or free radical inhibitors (bovine serum albumin (BSA), tyrosine, superoxyde dismutase (SOD), catalase, vitamin E). Furthermore the levels of glutathione peroxydase activity and reduced glutathione did not change after treatment by CM U1 as compared to controls. [less ▲]

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See detailLe visage de l'Autre ou la conscience du regard
Mélon, Marc-Emmanuel ULg

in Revue belge du cinéma (1997), 41

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See detailZastosowanie ultrasonografii w diagnostyce klinicznej ukladu rozrodczego u bydla
Gajewski, Z.; Hanzen, Christian ULg; Thun, R. et al

in Nowa Weterynaria (1997)

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See detailOncogenic potential of Tax requires phosphorylation on serines 106 et 293.
Willems, Luc ULg; Grimonpont, Catherine; Kerkhofs, Pierre et al

in Virus Research (1997), 47(2 -Special Issue), 121-122

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See detailProgramme EsQUIsE. Acquisition et interprétation de croquis d'architecture
Leclercq, Pierre ULg

in La lettre de l'IA (1997), 123

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See detailThe size of nanoparticles after their incorporation in gastroresistant spheroids
Duvivier, F; Grandfils, Christian ULg; Léonard, F et al

in Journal de Pharmacie de Belgique (1997), 52(3), 123

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See detailObesity and nutrition. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, F. et al

in Obesity Research (1997)

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See detailTransition probabilities for forbidden lines in Cr II
Quinet, Pascal ULg

in Physica Scripta (1997), 55

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See detailFin du Millénaire - fin de l'Agriculture
Schirmer, Jacek; Schmitz, Serge ULg

in Bulletin de la Société Géographique de Liège (1997), 33

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See detailJustinien et la langue latine. A propos d'un prétendu oracle rendu à Romulus d'après Jean le Lydien
Rochette, Bruno ULg

in Byzantinische Zeitschrift (1997), 90(2), 413-415

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See detailStudies on the O-J-I-P transient of chlorophyll fluorescence in relation to photosystem II assembly and heterogeneity in plastids of greening barley
Barthelemy, X.; Popovic, R.; Franck, Fabrice ULg

in Journal of Photochemistry and Photobiology B : Biology (1997), 39(3), 213-218

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of ... [more ▼]

The polyphasic variable fluorescence in saturating light (O-J-I-P transient, Strasser et al. (1995) Photochem. Photobiol. 61: 21-42) has been investigated in etiochloroplasts during the greening of etiolated leaves of Hordeum vulgare. The initial photochemical phase (O-J) due to reduction of the primary quinone acceptor Q(A) was found to represent a constant proportion (65-70%) of total variable fluorescence independent of greening time. The partial fluorescence quenching in the Q(A)-reduced state seems, therefore, to represent a basic property of PSII electron transport. The biphasic character of the slower J-I-P transient due to reduction of the plastoquinone pool developed progressively during the first hours of greening. in the same period of lime the proportion and rate constant of rapid PSII alpha sub-population increased, as calculated from the induction curve in the presence of DCMU. Etiochloroplasts or chloroplasts resuspended in low salt medium showed a low I level, which was restored upon readdition of 5 mM MgCl2 and NaCl. Salts also increased the apparent proportion of PSII alpha. These results suggest that the J-I and I-P phases of the induction curve are related to different rates of plastoquinone photoreduction by two distinct PSII populations. The effects of DMQ and of DCBQ on the O-J-I-P transient were also studied in (etio-)chloroplasts, In addition to the already reported quenching of the initial (F-0) and variable fluorescence by DCBQ, a slow fluorescence increase phase was found to appear upon the addition of DCBQ but not of DMQ. The latter observations confirm that DCBQ differs from DMQ by its higher efficiency as PSII electron acceptor. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailMoufang affine buildings have Moufang spherical buildings at infinity
Van Maldeghem, H.; Van Steen, Kristel ULg

in Glasgow Mathematical Journal (1997), 39(Part 3), 237-241

We show in a direct and elementary way that the spherical building at infinity of every rank 3 affine building which satisfies Tits' Moufang condition, is itself a Moufang building. This result is also ... [more ▼]

We show in a direct and elementary way that the spherical building at infinity of every rank 3 affine building which satisfies Tits' Moufang condition, is itself a Moufang building. This result is also true for higher rank affine buildings by Tits' classification [4]. [less ▲]

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See detailDetermination rapide par immunodosage de l'hemoglobine glyquee sur sang capillaire comparee a une methode d'affinite pour le boronate et capture d'ions sur sang veineux.
Bozet, Marie-Claire ULg; Gerard, Pascale ULg; Scheen, André ULg et al

in Annales de Biologie Clinique (1997), 55(2), 139-44

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary ... [more ▼]

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary blood obtained by a finger prick. In 100 ambulatory diabetic patients, we compared the results obtained with this method to those obtained in venous blood using a standard affinity chromatography laboratory method. Although both methods correlated (r = 0.88, p < 0.001), the mean +/- SD levels respectively obtained differed slightly (7.6 +/- 1.5 vs 79 +/- 1.4% p < 0.001). The 95% confidence interval of the difference was [-0.41. -0.14]. Considering a cut-off HbA1c value of 8%, as indicative of the need for treatment adjustment, 33 patients with the capillary blood immuno-assay method and 42 with the venous-blood affinity chromatography method were above that limit (Mc Nemar test, p < 0.05). In conclusion, the rapid assay of HbA1c in capillary blood can be useful for the management of some diabetic patients but the results are not readily exchangeable with those obtained from other standardized laboratory methods. Consequently, specific ranges and clinical decision limits must be determined. [less ▲]

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See detailUne grammaire de l'égyptien de la 18e dynastie
Winand, Jean ULg

in Orientalische Literaturzeitung (1997), 92

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See detailPlasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa.
Letiexhe, Michel ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Eating and Weight Disorders [=EWD] (1997), 2(2), 79-86

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose ... [more ▼]

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose tolerance test in nine women with anorexia nervosa and in nine age-matched normal-weight controls. Insulin secretion (ISR) was derived by deconvolution of plasma C-peptide levels, insulin clearance (MCR(I)) was obtained by dividing the area under the curve (AUC(0-180 min)) of ISR by the corresponding AUC of plasma insulin levels, insulin sensitivity (S(I)) and glucose effectiveness index (S(G)) were calculated by Bergman's minimal model. The anorectic women had markedly lower BMI values (13.7+/-0.6 vs 23.2+/-0.8 kg/m2, p<0.0001) and serum basal leptin levels (2.8+/-0.6 vs 8.9+/-1.8 ng/mL, p=0.005) than control women. The anorectic women exhibited clear-cut lower fasting and post-glucose plasma insulin levels but similar corresponding plasma C-peptide concentrations when compared to controls. Consequently, ISR was similar in both groups while MCR(I) was significantly increased in anorexia nervosa (MCR(I): 3320+/-881 vs 822+/-79 mL x min(-1) x m(-2), p<0.02). The index S(I) tended to be higher in anorectic women than in normal-weight subjects, but without reaching the level of statistical significance because of a high between-subject variability (20.2+/-5.7 vs 12.5+/-2.2 10(-5) x min(-1)/pmol x L(-1), NS). The index S(G) was similar in both groups (0.022+/-0.004 vs 0.018+/-0.002 min(-1), NS). In conclusion, low plasma insulin levels observed in women with anorexia nervosa result from high MCR(I) rather than from depressed insulin secretion. Insulin sensitivity is not systematically increased and glucose effectiveness is unchanged in anorectic women when compared to normal-weight controls. [less ▲]

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See detailEstimation of (co)variance components for Jersey type traits using a repeatability model
Gengler, Nicolas ULg; Wiggans, G. R.; Wright, J. R. et al

in Journal of Dairy Science (1997), 80(8), 1801-1806

(Co)variance components for final score and 15 linear type traits of Jersey cows were estimated by multitrait REML using multiple diagonalization and a repeatability model with 34,999 records of 22,354 ... [more ▼]

(Co)variance components for final score and 15 linear type traits of Jersey cows were estimated by multitrait REML using multiple diagonalization and a repeatability model with 34,999 records of 22,354 cows. Multiple diagonalization gave relative off-diagonals (ratio of squared off-diagonals to the product of diagonals) of <0.1%. Heritabilities and repeatabilities, respectively, were estimated as 0.29 and 0.48 for final score, 0.40 and 0.57 for stature, 0.26 and 0.39 for strength, 0.28 and 0.43 for dairy form, 0.13 and 0.25 for foot angle, 0.13 and 0.25 for rear legs (side view), 0.27 and 0.41 for body depth, 0.31 and 0.52 for rump angle, 0.22 and 0.33 for thurl width, 0.22 and 0.36 for fore udder attachment, 0.28 and 0.46 for rear udder height, 0.26 and 0.42 for rear udder width, 0.32 and 0.48 for udder depth, 0.20 and 0.36 for udder cleft, 0.29 and 0.46 for front teat placement, and 0.31 and 0.48 for teat length. Estimates of heritability generally were higher, and estimates of repeatability were lower, than values used previously for USDA genetic evaluations, which were based on data from the 1970s and early 1980s. Final score was highly correlated both genetically and phenotypically with dairy form and rear udder traits. These estimates of heritabilities and (co)variance components are necessary for multitrait genetic evaluation of linear type traits of US Jerseys. [less ▲]

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See detailManifestations indésirables des antidépresseurs
Charlier, Corinne ULg; Ansseau, Marc ULg; Pinto, Emmanuel ULg et al

in Toxicorama (1997), (Spécial LYON), 310-314

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See detailIgneous charnockites and related rocks from the Bjerkreim-Sogndal layered intrusion (Southwest Norway): a jotunite (hypersthene monzodiorite)-derived A-type granitoid suite
Duchesne, Jean-Clair ULg; Wilmart, Edith

in Journal of Petrology (1997), 38(3), 337-369

The upper part of the Bjerkreim-Sokndal layered intrusion (BKSK) comprises a suite of charnockitic granitoids (mangerite, quartz mangerite and charnockite) with some jotunites. The petrology and ... [more ▼]

The upper part of the Bjerkreim-Sokndal layered intrusion (BKSK) comprises a suite of charnockitic granitoids (mangerite, quartz mangerite and charnockite) with some jotunites. The petrology and geochemistry (major and trace elements) of 8 main rock types (88 samples) are considered. The rocks form a suite of K2O-rich alkali-calcic granitoids of A-type, deriving from jotunitic magma. Two trends of inferred liquids are distinguished: the main liquid line of descent which passes from jotunites through 2-pyroxene quartz mangerites to amphibole charnockites, the second one which encompasses olivine-bearing quartz mangerites and charnockites and is rooted into mangeritic liquids. Comparison with the Tellnes rock series reveals that contamination by leucogranitic material has taken place simultaneously with fractional crystallization in both BKSK trends. Zr, Rb, Cs, and Th are particularly sensitive to assimilation and the higher water content in BKSK. Zircon and apatite have saturated at the liquidus of quartz mangerite around 900°C, close to the FMQ buffer. The two-pyroxene quartz mangerites cannot have been equilibrated with the mangerite cumulates on which they rest. A major influx of magma took place when mangeritic cumulates were being deposited. It mingled and partly mixed with the resident contaminated magma. [less ▲]

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See detailAssessment of pain in herpes zoster: lessons learned from antiviral trials
Dworkin, R. H.; Carrington, D.; Cunningham, A. et al

in Antiviral Research (1997), 33(2), 73-85

Pain typically accompanies acute herpes zoster and, in a proportion of patients, it persists well beyond rash healing. Pain must therefore be analyzed in trials of antiviral agents in herpes zoster, but ... [more ▼]

Pain typically accompanies acute herpes zoster and, in a proportion of patients, it persists well beyond rash healing. Pain must therefore be analyzed in trials of antiviral agents in herpes zoster, but different methods have been used to analyze pain in recent published trials. These reports are reviewed and their methodological strengths and weaknesses examined. Based on this review, recommendations for the design and analysis of future trials of antiviral agents in herpes zoster are proposed. The principal recommendation is that antiviral efficacy should be evaluated both by distinguishing post-herpetic neuralgia from acute pain and by considering pain as a continuum. The primary endpoint should address both the prevalence and duration of post-herpetic neuralgia and should be examined in those patients who have post-herpetic neuralgia. Adopting the proposed recommendations in design and analysis of future trials should facilitate comparison across trials of the efficacy of antiviral agents in the treatment of herpes zoster. [less ▲]

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See detailCompte rendu de A. ANGENENDT, Heilige und Reliquien, Munich, 1994
George, Philippe ULg

in Francia. 1, Mittelalter (1997)

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See detailIn vivo and in vitro development of preantral follicles
Van den Hurk, R.; Bevers, M. M.; Beckers, Jean-François ULg

in Theriogenology (1997), 47(1), 73-82

The paper presents the state of the art concerning the in vitro growth and differentiation of preantral follicles, i.e. from the primordial to the antral stage, in mammals. Attention is paid to their ... [more ▼]

The paper presents the state of the art concerning the in vitro growth and differentiation of preantral follicles, i.e. from the primordial to the antral stage, in mammals. Attention is paid to their normal structure and development, nomenclature, isolation and culture methods, effects of systemic and local compounds on their development, and viability of isolated and cultured follicules, with special reference to the bovine. In vivo, various endocrine and locally produced compounds stimulate neovascularization or innervation of small follicles, which provide nutrients, cytokines, hormones and neuropeptidergic substances, necessary of survival of follicles and initiation of follicle growth. In vitro, FSH, activin, EGF, TGFs and IVP seem important for survival and growth of cultured preantral follicles. However, many reported in vitro effects of hormonal compounds on preantral follicles, especially on those from the bovine, have to be interpreted carefully, since these studies presented little information on oocyte quality. In contrast to preantral follicles from small laboratory animals, pigs and humans, those from cows will not soon be usable for IVP, since their oocyte is relatively small and their growth rate relatively slow. Although practical application of especially small preantral for IVP of live-stock species still is far away, it should not be considered an utopia. [less ▲]

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See detailThe spectrum of 67-kD laminin receptor expression in breast carcinoma progression.
Viacava, P.; Naccarato, A. G.; Collecchi, P. et al

in Journal of Pathology (The) (1997), 182(1), 36-44

Laminin is a glycoprotein of the basement membrane (BM), involved in a variety of normal and pathological cellular events including tumour invasion and metastasis. Cells bind laminin through different ... [more ▼]

Laminin is a glycoprotein of the basement membrane (BM), involved in a variety of normal and pathological cellular events including tumour invasion and metastasis. Cells bind laminin through different types of receptor. The 67-kD laminin receptor (67LR) is a cell-surface protein which binds laminin with high affinity. 67LR expression has been shown to increase in neoplastic cells, compared with normal tissues, and 67LR seems to play an important role during the first steps of neoplastic progression. In this study, 67LR expression was analysed during the morphological phases of breast cancer progression from normal tissue to invasive carcinoma. A total of 506 formalin-fixed, paraffin-embedded normal breast structures and lesions were stained by immunohistochemistry usign the MLuC5 monoclonal antibody, which is specific for 67LR. The results show that in normal breast and in any kind of breast lesion, myoepithelial and endothelial cells express 67LR. While 67LR is not seen in the epithelium of normal breast, cysts, adenosis, and benign tumours, it is expressed in the epithelial cells of several hyperplasias and carcinomas in situ, both ductal and lobular, as well as in all invasive carcinomas. The 67LR-positive cell subpopulation expands from hyperplastic lesions to invasive carcinoma, suggesting that 67LR could be related to the induction and progression of breast cancer. [less ▲]

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See detailProtéinas placentárias em mamíferos
Melo de Sousa, Noelita; de Figueiredo, José Ricardo; Gonçalves, Paulo Bayard Dias et al

in Ciência Animal (1997), 7(1), 43-55

During the past twenty years, several new placental proteins have been isolated and characterized in woman and several animal species. Among these proteins, it can be mentioned chorionic gonadotrophins ... [more ▼]

During the past twenty years, several new placental proteins have been isolated and characterized in woman and several animal species. Among these proteins, it can be mentioned chorionic gonadotrophins, placental lactogens, interferon tau, pregnancy specific and pregnancy-associated glycoproteins. In spite of the importance of these studies, there are few papers that describe fundamental aspects of these placental proteins such as physical-chemical pregnancy diagnosis methods. Thus, the aim of this report is to present an overview on the major aspects of placental proteins studied up to now, as well as to consider perspectives for their applications in the future in veterinary practice. [less ▲]

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See detailRecherche d'information et pragmatisme : II. Utilité sociale de la confirmation d'hypothèses
Dardenne, Benoît ULg; Leyens, J.; Yzerbyt, V. Y.

in Année Psychologique (L') (1997), 97

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See detailA method to correct the shape of pressure waves obtained from pulmonary fluid-filled catheters
LAMBERMONT, Bernard ULg; GERARD, P; DETRY, Olivier ULg et al

in American Journal of Respiratory & Critical Care Medicine (1997), 2

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See detailEvidence for enhanced inflammatory cell activity, ICAM-1 expression and eosinophil chemotactic activity in the sputum of asthmatics.
Louis, Renaud ULg; Shute, J.; Biaggi, S. et al

in American Journal of Respiratory & Critical Care Medicine (1997), 155(2), 466-472

We have applied the technique of sputum induction by hypertonic saline in asthmatics and nonatopic control subjects to study an array of indices of airway inflammation believed to be relevant to asthma ... [more ▼]

We have applied the technique of sputum induction by hypertonic saline in asthmatics and nonatopic control subjects to study an array of indices of airway inflammation believed to be relevant to asthma pathogenesis. Compatible with a central role for eosinophils and mast cells in asthma, sputum of asthmatic subjects contained increased numbers of eosinophils and levels of eosinophil cationic protein (ECP) and mast cell tryptase. Eosinophil numbers, and ECP and histamine levels correlated with the degree of methacholine airways responsiveness, and ECP, tryptase, and histamine correlated with raised concentrations of albumin. Using the micro-Boyden chamber technique eosinophil chemotactic activity was identified only in the sputum from asthmatics. The correlation between the raised levels of total IgA, IL- 8/IgA complexes, and tryptase and the degree of sputum eosinophilia and ECP levels, suggests possible mechanisms for eosinophil chemotaxis and activation in asthma. Row cytometric analysis of sputum lymphocytes showed an increase in CD4+ T cells and T cells expressing intercellular adhesion molecule-1 (ICAM-1) in asthma which, together with the finding of raised levels of soluble ICAM-1 in the sputum, indicates upregulation of this adhesion molecule. Finally, the proportion of CD16+ natural killer (NK) cells was reduced in the sputum of asthmatics. These observations highlight the importance of the airway inflammation in causing asthma and further confirm the usefulness of sputum induction as a tool in asthma research. [less ▲]

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See detailConcordanze del «Canto novo» di Gabriele d’Annunzio.
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (1997)

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See detailLes comportements des enseignants dans la perspective d'un traitement différencié des élèves
Piéron, Maurice; Ledent, Maryse; Pirottin, Véronique et al

in Revue de l'Education Physique (1997), 4

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe ... [more ▼]

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe est hétérogène, chaque enfant étant singulier, différent dans ses valeurs, ses attitudes, ses potentialités et ses compétences. Chacun apprend à un rythme différent, plus rapidement que la moyenne dans des domaines, moins rapidement dans d'autres. ... [less ▲]

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See detailLa langue des Cariens. A propos de B 867
Rochette, Bruno ULg

in Glotta : Zeitschrift für Griechische und Lateinische Sprache (1997), 74

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See detailOn endostyle ultrastructure in two new species of doliolid-like tunicates
Compère, Philippe ULg; Godeaux, Jean

in Marine Biology (1997), 128

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See detailAn introduction to ET-LOTOS for the description of time-sensitive systems
Léonard, Luc; Leduc, Guy ULg

in Computer Networks & ISDN Systems (1997), 29(3), 271-292

Enhanced Timed-LOTOS, called ET-LOTOS, is an extension of LOTOS allowing the modelling of time-sensitive systems (i.e. systems whose behaviour is influenced by the passing of time). It is the basis of the ... [more ▼]

Enhanced Timed-LOTOS, called ET-LOTOS, is an extension of LOTOS allowing the modelling of time-sensitive systems (i.e. systems whose behaviour is influenced by the passing of time). It is the basis of the timed extension of LOTOS currently developed by ISO (1995). The purpose of this paper is to present ET-LOTOS in a tutorial style and show its applicability. The detailed study of the formal semantics is addressed in another paper. A collection of small but realistic, examples illustrates a wide variety of time-sensitive protocol mechanisms. These examples are used to introduce and justify the extensions of our language. Finally, the basics of the formal semantics are given and a comparison is made with other timed formalisms. [less ▲]

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See detailComment j'explore ... le syndrome d'insulinoresistance grace a ses marqueurs biologiques.
Luyckx, Françoise ULg; Scheen, André ULg; Gielen, Jean-Louis ULg et al

in Revue Médicale de Liège (1997), 52(10), 686-91

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See detailDeux POHLIA méconnus d'Alsace: P.lutescens (Limpr.) Lindb. et P. lescuriana (Sull.) Andrews
Vanderpoorten, Alain ULg

in Bulletin de la Société d'Histoire Naturelle de Colmar (1997), 63

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See detailLa Belgique: Diversité territoriale
Merenne-Schoumaker, Bernadette ULg; Van der Haegen, H.; Van Hecke, E.

in Bulletin du Crédit Communal (1997), (202), 144

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques ... [more ▼]

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques entre 1981 et 1991. 155 cartes en couleurs. [less ▲]

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See detailSynthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas
Masereel, B.; Ouedraogo, R.; Dogne, J.-M. et al

in European Journal of Medicinal Chemistry (1997), 32

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See detailExpression of insulin-related peptides in the human thymus
Geenen, Vincent ULg; Lefebvre, Pierre ULg

in International Diabetes Monitor (1997), 9

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See detailLes téléports en Europe: état actuel et perspectives offertes par les "call centers"
Jacob, Damien ULg

in Revue Géographique de l'Est (1997), 37(4), 273-284

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts ... [more ▼]

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts partagés et les téléports " hub ", concentrant les flux de communication en un point central. Les téléports ciblent des entreprises exigeant un haut niveau de services en télécommunications, par exemple les centres d'appels téléphoniques. Cette activité, en pleine expansion en Europe, recherche une main-d'œuvre multilingue pouvant assurer par téléphone des services d'information, de conseil, de vente et d'après-vente. Les téléports peuvent donc devenir des outils attractifs pour attirer ce créneau particulièrement porteur en création d'emplois, même si ces derniers sont pour une bonne part une transformation d'anciennes tâches et paraissent potentiellement faciles à délocaliser vers des pays à faible coût du travail. [less ▲]

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See detailImaging the solar corona in the EUV
Delaboudiniere, J.-P.; Stern, R. A.; Maucherat, A. et al

in Advances in Space Research (1997), 20

The SOHO (SOlar and Heliospheric Observatory) satellite was launched on December 2nd 1995. After arriving at the Earth-Sun (L1) Lagrangian point on February 14th 1996, it began to continuously observe the ... [more ▼]

The SOHO (SOlar and Heliospheric Observatory) satellite was launched on December 2nd 1995. After arriving at the Earth-Sun (L1) Lagrangian point on February 14th 1996, it began to continuously observe the Sun. As one of the instruments onboard SOHO, the EIT (Extreme ultraviolet Imaging Telescope) images the Sun's corona in 4 EUV wavelengths. The He II filter at 304 AË images the chromosphere and the base of the transition region at a temperature of 5 - 8 x 10^4 K; the Fe IX-X filter at 171 AË images the corona at a temperature of ~ 1.3 x 10^6 K; the Fe XII filter at 195 AË images the quiet corona outside coronal holes at a temperature of ~ 1.6 x 10^6 K; and the Fe XV filter at 284 AË images active regions with a temperature of ~ 2.0 x 10^6 K. About 5000 images have been obtained up to the present. In this paper, we describe also some aspects of the telescope and the detector performance for application in the observations. Images and movies of all the wavelengths allow a look at different phenomena present in the Sun's corona, and in particular, magnetic field reconnection. [less ▲]

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See detailSympathetic modulation of hypoxic pulmonary vasoconstriction in intact dogs
Brimioulle, Serge; Vachiéry, Jean-Luc; Brichant, Jean-François ULg et al

in Cardiovascular Research (1997), 34

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See detailLa responsabilité civile et professionnelle des administrateurs
Caprasse, Olivier ULg

in Actualités du Droit (1997)

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See detailSurface-active properties of surfactin iturin A mixtures produced by Bacillus subtilis
Razafindralambo, Hary ULg; Popineau, Yves; Deleu, Magali ULg et al

in Langmuir (1997), 13(23), 6026-6031

Surface-active properties including dynamic adsorption, monolayer stability, micelle forming capacity, and foaming aptitudes of surfactin-C-15/iturin A-C-15 mixtures were studied. Surfactin-C-15 and ... [more ▼]

Surface-active properties including dynamic adsorption, monolayer stability, micelle forming capacity, and foaming aptitudes of surfactin-C-15/iturin A-C-15 mixtures were studied. Surfactin-C-15 and iturin A-C-15 molecules interact in synergism on the most surface-active properties evaluated at 20 degrees C at the air-water interface and in aqueous solution (pH 8.0). The synergism is positive on the adsorption effect, monolayer stability, foam density, and liquid stability in foam, whereas it is negative on the adsorption rate. No synergism occurs an micelle forming capacity, but surfactin-C-15 and iturin A-C-15 form mixed micelles when the solution contains a low proportion of surfactin-C-15.ses the synergistic effect is maximum when surfactin-C-15 and iturin A-C-15 molecules are mixed in a 2:3 ratio. This is attributed to the surfactin/iturin A complex formation resulting from specific interactions among two surfactin-C-15 molecules and three iturin A-C-15 molecules. A model of such a complex formation is proposed. [less ▲]

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See detailIntroduction
Delhalle, Nancy ULg

in Alternatives Théâtrales (1997), 55

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See detailLes modes de transmission du virus de l'hépatite C
Delwaide, Jean ULg; Gerard, Christiane ULg; Sondag, Danièle ULg et al

in Médecine & Chirurgie Digestives (1997), 26

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See detailProprietes interfaciales des films de gluten de farines de qualites boulangeres differentes.
Balla, A.; Blecker, Christophe ULg; Razafindralambo, Hary ULg et al

in Sciences des Aliments (1997), 17(3), 271-278

Interfacial properties of gluten proteins are important in determining flour breadmaking quality especially the gas bubbles stability in dough, which influences the loaf volume and crumb texture. The ... [more ▼]

Interfacial properties of gluten proteins are important in determining flour breadmaking quality especially the gas bubbles stability in dough, which influences the loaf volume and crumb texture. The interfacial properties of gluten extracted from four commercial flours have been studied. The behaviour of gluten monolayer spread at the air-water interface is influenced by the gliadins/glutenins ratio. Films of gluten extracted from flours with high gliadins/glutenins ratio spread more quickly, present a higher stability (Pi c) and are more resistant under high compression. [less ▲]

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See detailIn vivo binding of [F-18]altanserin to rat brain 5HT(2) receptors: A film and electronic autoradiographic study
Biver, Françoise; Lotstra, Françoise; Monclus, M. et al

in Nuclear Medicine and Biology (1997), 24(4), 357-360

To further validate its use in positron emission tomography (PET), we studied the binding of [18F]altanserin, a specific 5HT2 radioligand, in the rat brain using in vivo autoradiography. Distribution of ... [more ▼]

To further validate its use in positron emission tomography (PET), we studied the binding of [18F]altanserin, a specific 5HT2 radioligand, in the rat brain using in vivo autoradiography. Distribution of [18F]altanserin binding was comparable to the in vitro mapping of 5HT2 receptors reported in the literature. Selective displacers were used to test the reversibility and the selectivity of this radioligand. Specific binding of [18F]altanserin in the rat frontal cortex was quantified by direct counting with an electronic imaging system and by quantification on digitalized autoradiograms. Close results of about 30 pmol/g were obtained with both methods. Our data confirmed that [18F]altanserin is a valid tracer for 5HT2 receptors binding studies. [less ▲]

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See detailA modification of convex approximation methods for structural optimization
Zhang, Wei-Hong; Fleury, Claude ULg

in Computers & Structures (1997), 64(1-4), 89-95

The most popular convex approximation methods used today in structural optimization are discussed in this paper: the convex linearization method (CONLIN), the method of the moving asymptotes (MMA) and the ... [more ▼]

The most popular convex approximation methods used today in structural optimization are discussed in this paper: the convex linearization method (CONLIN), the method of the moving asymptotes (MMA) and the sequential quadratic programming method (SQP). Modifications are made to enhance the reliability of the CONLIN method. In addition, a generalized MMA (GMMA) is established. However, in view of practical difficulties of evaluating second-order derivatives, a fitting scheme is proposed in this work to adjust the convexity of the approximation based on the available function value at the preceding design iteration. Numerical results show that this simple scheme is efficient in our applications. [less ▲]

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See detailLe syndrome hépato-pulmonaire
Lamproye, Anne ULg; Weber, T.; Delwaide, Jean ULg et al

in Revue Médicale de Liège (1997), 52(10), 666-670

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See detailIn vivo study of enhancing factors for guided bone formation
Biewer, Bob; Van Heusden, Alain ULg; Rompen, Eric ULg

in Journal of Clinical Periodontology (1997), 11

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See detailReactivite bronchique chez les patients diabetiques.
Piéron, Maurice ULg; Scheen, André ULg; Corhay, Jean-Louis ULg et al

in Revue des Maladies Respiratoires (1997), 14(5), 379-85

The data of the literature concerning bronchial reactivity in diabetic patients are controversial. Therefore, we studied the influence of the presence of a diabetic cardiac autonomic neuropathy (CAN) on ... [more ▼]

The data of the literature concerning bronchial reactivity in diabetic patients are controversial. Therefore, we studied the influence of the presence of a diabetic cardiac autonomic neuropathy (CAN) on the ventilatory parameters measured during a methacholine-induced bronchoconstriction test. Ten insulin-dependent diabetic patients without CAN, ten insulin-dependent diabetic patients with CAN and ten healthy volunteers, all non-smokers and free of respiratory symptoms, have undergone a functional respiratory check-up before the methacholine test. The presence of CAN was classically studied by the decrease in heart rate changes during three standardized tests (deep breathing at 6 cycles/min, Valsalva manoeuver, orthostatism) which all mainly explore the parasympathetic function. The bronchial response to methacholine was similar in the healthy subjects and in the diabetic patients without CAN. However, the fall in forced expiratory volume in 1 second induced by the highest dose of methacholine was significantly less marked in the diabetic subjects with CAN than in the two other groups. These results suggest that the diabetic autonomic neuropathy also involves the vagal innervation of the respiratory tract. [less ▲]

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See detailDifferential expression of galectin 3 and galectin 1 in colorectal cancer progression.
Sanjuan, X.; Fernandez, P. L.; Castells, A. et al

in Gastroenterology (1997), 113(6), 1906-15

BACKGROUND & AIMS: Galectins are beta-galactoside-binding proteins possibly involved in tumor progression. The aim of this study was to determine the pattern of galectin 3 and galectin 1 expression and ... [more ▼]

BACKGROUND & AIMS: Galectins are beta-galactoside-binding proteins possibly involved in tumor progression. The aim of this study was to determine the pattern of galectin 3 and galectin 1 expression and involvement in colorectal cancer progression. METHODS: Galectin 3 expression was examined immunohistochemically in 39 samples of normal mucosae, 25 adenomas, 87 carcinomas, and 39 lymph node metastases. Galectin 1 was analyzed in 25 samples of mucosae, 15 adenomas, 25 carcinomas, and 11 metastases. Western blot analysis was also performed. RESULTS: All normal mucosae showed strong nuclear galectin 3 expression, which was down-regulated in the neoplastic progression, because only 60% of adenomas, 48% of carcinomas, and 44% of metastases were strongly positive (P < 0.0001). Cytoplasmic expression was down-regulated in adenomas (16%) but increased again in carcinomas (64%) (P < 0.0001). Galectin 1 expression was mainly detected in stromal cells and correlated with tumor progression from normal mucosae to adenomas and carcinomas (P < 0.0001). CONCLUSIONS: Galectin 3 expression is down-regulated in the initial stages of neoplastic progression, whereas a dissociated cytoplasmic expression increases in later phases of tumor progression. Galectin 1 in colorectal mucosa is predominantly a stromal product whose overexpression is associated with the neoplastic progression of colorectal cancer. [less ▲]

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See detailDe différences en disparités : les effets d'un système éducatif 'non compréhensif'
Lafontaine, Dominique ULg

in Scientia Paedagogica Experimentalis (1997), XXXIV(2), 267-281

Cet article examine, à travers le cas de la Communauté française de Belgique, les liens entre l'organisation du système éducatif au début du secondaire (présence de redoublements ou promotion automatique ... [more ▼]

Cet article examine, à travers le cas de la Communauté française de Belgique, les liens entre l'organisation du système éducatif au début du secondaire (présence de redoublements ou promotion automatique, organisation en tronc commun ou en filières, présence ou non d'une carte scolaire) et différents indices de performance ou d'équité : performances moyennes en lecture à un test international comparatif, degré d'hétérogénéité des performances entre élèves, disparités de rendement selon l'établissement ou la filière fréquenté(e). Les résultats montrent que le redoublement, largement pratiqué en Communauté française de Belgique, ne débouche ni sur des meilleures performances, ni sur une réduction sensible des disparités entre élèves. L'absence de tronc commun et de sectorisation engendre en outre de fortes disparités selon la filière et selon l'établissement fréquenté. Le premier degré du secondaire de la Communauté française, organisé en système 'non compréhensif', semble ainsi de nature à amplifier plutôt qu'à corriger les inégalités entre élèves issus du primaire. [less ▲]

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See detailColestasis asociada a ticlopidina
Diaz Fuenzalida, A.; VALDES SOCIN, Hernan Gonzalo ULg; Laudano, O. et al

in Gastroenterologia y Hepatologia (1997), 20(3), 128-30

The case of a 56-years-old male with cholestasis associated with ticlopidine is presented. Cholestasis is an infrequent adverse effect of this drug. The patient was admitted to hospital because of ... [more ▼]

The case of a 56-years-old male with cholestasis associated with ticlopidine is presented. Cholestasis is an infrequent adverse effect of this drug. The patient was admitted to hospital because of jaundice, choluria, and itching of one month of evolution. The patient had taken ticlopidine twice a day for 3 months up to one week prior to admission for peripheral arteriopathy. Biopsy was performed showing acinar cholestasis and portal inflammatory infiltrate compatible with cholestasis due to hypersensitivity. Ticlopidine was discontinued by the patient himself one week prior to admission. The drug was not readministered and the evolution of the clinical and biochemical parameters of cholestasis decreased. The patient was asymptomatic and laboratory data were normal 4 months later. [less ▲]

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See detailPirlindole: a selective reversible inhibitor of monoamine oxidase A. A review of its preclinical properties.
Bruhwyler, J.; Liégeois, Jean-François ULg; Geczy, J.

in Pharmacological Research (1997), 36(1), 23-33

Pirlindole is a tetracyclic compound that has been characterized as a potential antidepressant drug. It has pharmacological characteristics in common with both tricyclic antidepressants and classical ... [more ▼]

Pirlindole is a tetracyclic compound that has been characterized as a potential antidepressant drug. It has pharmacological characteristics in common with both tricyclic antidepressants and classical irreversible monoamine oxidase inhibitors. Its main mechanism of action consists of a selective and reversible inhibition of monoamine oxidase A. Secondarily, it exerts an inhibitory effect on noradrenaline and 5-hydroxytryptamine reuptakes. It has no effect on the dopaminergic and cholinergic systems. It has only a low potential for amplifying tyramine and noradrenaline pressor effect, which makes one expect that it will not be at the basis of a 'cheese effect'. Pirlindole has an absolute bioavailability of between 20 and 30% due to an extensive first-pass effect. Orally, the Tmax varies between 2.5 and 6 h in the rat and 0.8 and 2 h in the dog. Two phases of elimination (7.5 and 34-70 h) are measured in the rat and three phases in the dog (1.3, 10.8 and 185 h); it is extensively metabolized. The rat eliminates mainly unconjugated products while the dog eliminates mostly conjugated products. Acute and chronic toxicological studies have not revealed potentially dangerous effects of the drug at the usual doses. It does not present measurable mutagenic, clastogenic or carcinogenic properties. Thus, pirlindole shows pharmacological, pharmacokinetic and toxicological properties which make it suitable for the management of depression. [less ▲]

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See detailEtude morphométrique du sabot et du petit sésamoïde du cheval
Gabriel, Annick ULg; Detilleux, J.; Jolly, S. et al

in Annales de Médecine Vétérinaire (1997), 147

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See detailSurface Molecular Structure of Self-Assembled Alkanethiols Evidenced by UPS and Photoemission with Synchrotron Radiation
Duwez, Anne-Sophie ULg; Di Paolo, Stéphanie; Ghijsen, Jacques et al

in Journal of Physical Chemistry B (1997), 101

With the aim of investigating the configurational and conformational characteristics of monolayers of alkanethiols on gold by means of a photoemission experiment, we compare the valence data obtained from ... [more ▼]

With the aim of investigating the configurational and conformational characteristics of monolayers of alkanethiols on gold by means of a photoemission experiment, we compare the valence data obtained from these layers using synchrotron radiation and ultraviolet photoemission spectroscopy (UPS). The incident energy used for synchrotron radiation has been chosen very close to the Cooper minimum of the 5d levels of gold, in order to limit as much as possible interference from the substrate. The recorded spectra differ markedly from one sample to another, notwithstanding their closely related chemical nature. These variations are compared consistently with semiquantitative simulations on model clusters and found thereby to reflect specifically the influence of the connectivity and of specific interactions on the electronic structure of long hydrocarbon chains [less ▲]

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See detailChanging sensitivity to duration in human scalar timing: An experiment, a review, and some possible explanations
Ferrara, André ULg; Lejeune, Helga ULg; Wearden, J. H.

in Quarterly Journal of Experimental Psychology. B, Comparative & Physiological Psychology (1997), 50B

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See detailCombined Effect of Web 2086 (Paf Antagonist) and Ketoprofen (Nsaid) on Paf-Induced Ex Vivo Platelet Aggregation in Bovine
Bastos da Silva, Miriam; Herion, Francine ULg; Raskinet, Renée ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1997), 44(2), 65-71

The effect of the specific PAF-antagonist WEB 2086, a thieno-triazolo-diazepine, and ketoprofen, a NSAID, was investigated on PAF-induced bovine platelet aggregation measured ex vivo in platelet-rich ... [more ▼]

The effect of the specific PAF-antagonist WEB 2086, a thieno-triazolo-diazepine, and ketoprofen, a NSAID, was investigated on PAF-induced bovine platelet aggregation measured ex vivo in platelet-rich plasma (PRP). WEB 2086 was infused intravenously over 1 min followed immediately by ketoprofen administration over 1 s (both drugs = 3 mg/kg), in a group of six healthy male Friesian calves. Depending on the PAF concentration, a reversible (10(-8)-10(-9) mol/l) and irreversible (10(-5)-10(-7) mol/l) platelet aggregation was observed. The reversible aggregation was completely blocked by pretreatment of the animal with WEB 2086 and ketoprofen. The inhibitory effects observed during the irreversible aggregation were 47.22%, 54.00% and 88.00% at 10(-5), 10(-6) and 10(-7) mol/l PAF, respectively. Moreover, the aggregation obtained in these condition became reversible. Maximal inhibitory effect of WEB 2086 and ketoprofen on PAF-induced platelet aggregation in calves was observed within 30 min after administration of both drugs. This inhibition persisted even after 24 h and was significantly different from control with P < 0.05. The combined effect of both drugs exceeded the sum of the individual effects (synergism). It was concluded that WEB 2086 and ketoprofen very effectively blocked PAF-induced bovine platelet aggregation in platelet-rich plasma. The study also suggested a synergism between both substances. [less ▲]

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See detailLinear Benard-Marangoni instability in rigid circular containers
Dauby, Pierre ULg; Lebon, Georgy ULg; Bouhy, E.

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1997), 56(1), 520-530

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See detailDarkness promotes flowering in the absolute long-day requiring plant, Lolium temulentum L. Ceres
Périlleux, Claire ULg; Bernier, Georges ULg; Kinet, Jean-Marie

in Journal of Experimental Botany (1997), 48(307), 349--351

Vegetative plants of the long-day grass Lolium temulentum L. Ceres were exposed to threshold long days or light breaks. Protracted darkness given just afterwards clearly promoted flowering and was weakly ... [more ▼]

Vegetative plants of the long-day grass Lolium temulentum L. Ceres were exposed to threshold long days or light breaks. Protracted darkness given just afterwards clearly promoted flowering and was weakly inductive on its own. The promotive effect of darkness was restricted to floral induction since further apical development was weak. [less ▲]

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See detailOzone-Induced Stimulation of Pulmonary Sympathetic Fibers: A Protective Mechanism against Edema
Delaunois, Annie ULg; Segura, P.; Dessy, Cécile ULg et al

in Toxicology and Applied Pharmacology (1997), 147(1), 71-82

Tropospheric ozone exerts well-described toxic effects on the respiratory tract. Less documented, by contrast, is the ability of ozone to induce protective mechanisms against agents that are toxic to the ... [more ▼]

Tropospheric ozone exerts well-described toxic effects on the respiratory tract. Less documented, by contrast, is the ability of ozone to induce protective mechanisms against agents that are toxic to the lungs. In particular, interactions between ozone and the sympathetic nervous system have never been considered. Using a model of permeability edema in isolated perfused rabbit lungs, we report here that, immediately after exposure of rabbits to 0.4 ppm ozone for 4 hr, the pulmonary microvascular responses to acetylcholine and substance P are completely blocked. Several lines of evidence, including partial inhibition of the ozone-induced protective effect by several drugs (alpha2- and beta-adrenergic antagonists, neuropeptide Y antagonist, guanethidine), measured levels of released catecholamines in blood and urine and the in vitro response of isolated lungs exposed to 0.4 ppm ozone all seem to suggest that ozone can stimulate pulmonary adrenergic fibers and induce the local release of catecholamines and neuropeptide Y, this resulting in transient protection against pulmonary edema. We also showed that, 48 hr after the exposure, ozone increased the baseline microvascular permeability and the response to low concentrations of acetylcholine [less ▲]

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See detailLes hermeneis dans le christianisme primitif. Aux sources du schisme byzantin
Rochette, Bruno ULg

in Byzantion : Revue Internationale des Etudes Byzantines (1997), 67

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See detailCompte rendu de L. Couloubaritsis, J.-J. Wunenburger, La couleur, Bruxelles, 1993 (Recueil, 4)
Marganne, Marie-Hélène ULg

in Archives Internationales d'Histoire des Sciences (1997), 47

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See detailSur les accents et les marques de quantité dans les papyrus latins
Rochette, Bruno ULg

in Zeitschrift für Papyrologie und Epigraphik (1997), 119

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See detailGenetic Structure Of A Lima Bean Base Collection Using Allozyme Markers
Maquet, A.; Bi, Iz.; Delvaux, M. et al

in Theoretical & Applied Genetics = Theoretische und Angewandte Genetik (1997), 95(5-6),

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See detailSurveillance des états hypertensifs sévères
Brichant, Jean-François ULg

in Gunaïkeia (1997), 2

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See detailSoil oribatid mite communities (Acari: Oribatida) from high Shaba (Zaïre) in relation to vegetation
Noti, M.-I.; André, H. M.; Dufrêne, Marc ULg

in Applied Soil Ecology (1997), 5(1), 81-96

Soil oribatid mite communities from three vegetation types (forest, woodland and savanna) are described in Luiswishi (high Shaba, Zaïre) and 151 species were recorded. Oribatid communities are organized ... [more ▼]

Soil oribatid mite communities from three vegetation types (forest, woodland and savanna) are described in Luiswishi (high Shaba, Zaïre) and 151 species were recorded. Oribatid communities are organized along a successional gradient which parallels the regressive sere defined by phytosociologists and going from the dense forest ("muhulu"), the local climax, to the savanna, passing through the woodland ("miombo"). Within this gradient, oribatid communities may vary depending on the habitat (presence of grass, high termitaria). The impact of seasons (dry vs. rainy season) is weak in the forest but drastic in savanna. The various soil oribatid communities are related to man's activities since the regressive sere results from repeated burnings and associated agricultural practices. [less ▲]

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See detailAlteration of radiation response in vitro by simultaneous modulation of the de novo and salvage pathways to deoxynucleoside triphosphate pool by (E)-2′-Deoxy-(Fluoromethylene)cytidine and thymidine analogs
Coucke, Philippe ULg; Li, Ye-Xiong; Cottin, Eliane et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 39(2 (supp1)), 257

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See detailRecommandations pour la prévention de l’infection tuberculeuse dans les institutions de soins
Gosset, Christiane ULg; Prignot, J.; Schandevyl, W. et al

in Revue de l’Association Belge des Technologues de Laboratoire = Tijdschrift van de Belgische Vereniging van Laboratoriumtechnologen (1997), 24(1), 50-56

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See detailCompte rendu de A. Krug, Heilkunst und Heilkult. Medizin in der Antike, 2e édition, München, 1993
Marganne, Marie-Hélène ULg

in Revue Belge de Philologie et d'Histoire (1997), 75(1), 213-214

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See detailL’arsénopyrite du Massif de Stavelot, Belgique
Hatert, Frédéric ULg

in Bulletin de la Société Royale des Sciences de Liège (1997), 66

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See detailAutoregulation of endogenous glucose production in man.
Tappy, L.; Tounian, P.; Paquot, Nicolas ULg

in Biochemical Society Transactions (1997), 25(1), 11-3

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See detailAttitude des élèves face à l'école et au cours d'éducation physique, âge et retard scolaire
Piéron, Maurice; Delfosse, Catherine; Ledent, Maryse et al

in Revue de l'Education Physique (1997), 37(1), 31-41

Le terme motivation fait partie du langage habituel des psychologues, des enseignants, des sportifs,... Nous pourrions continuer cette liste sans parvenir à lui donner un caractère exhaustif. Parfois ... [more ▼]

Le terme motivation fait partie du langage habituel des psychologues, des enseignants, des sportifs,... Nous pourrions continuer cette liste sans parvenir à lui donner un caractère exhaustif. Parfois utilisé de manière abusive, ce concept présente néanmoins des aspects théoriques et pratiques fondamentaux. A la notion de motivation, on associe très fréquemment celle d'attitude. Toutes deux sont définies en référence à l'affect, c'est-à-dire à une impression d'attraction ou de répulsion vis-à-vis d'un objet déterminé. ... [less ▲]

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See detailL'abord coelioscopique des pheochromocytomes est-il acceptable? Reflexions a propos d'une etude prospective de 6 cas personnels.
Hamoir, Etienne ULg; Defechereux, Thierry ULg; Nguyen Dang, Delphine ULg et al

in Annales d'Endocrinologie (1997), 58(1), 65-74

Today, laparoscopy is for us the technique of choice for approaching presumed benign adrenal tumors. With regards to pheochromocytoma however, two major questions must be addressed. First, is it ... [more ▼]

Today, laparoscopy is for us the technique of choice for approaching presumed benign adrenal tumors. With regards to pheochromocytoma however, two major questions must be addressed. First, is it acceptable to resect potentially multifocal tumors with such a targeted approach? Second, can peroperative hemodynamic changes be anticipated and controlled by the anesthetist, taking into account the additional effects of pneumoperitoneum and catecholamine release on the cardiovascular system? The present prospective study attempts to answer these two questions. From November 1993 to November 1995 we operated on four women and two men, with ages ranging from 33 to 71 years (mean of 47) and a mean Body Mass Index of 25 kg/m2 (range 17-35). Four patients were assigned ASA (American Society of Anesthesiologists) physical status 2, one grade 1 and one grade 3. Comprehensive preoperative work-up, including a CT scan and an I131 MIBG Scan in all, a C11 Hydroxyephedrine PET Scan in 4 and a MRI in one patient, showed a solitary lesion in each case. There were four right-sided and two left-sided tumors, ranging from 30 to 60 mm in diameter. Laparoscopy was always performed transperitoneally. Systemic and pulmonary hemodynamics were thoroughly assessed. Epinephrin and norepinephrin concentrations were measured at the 10 key-time of surgery. Use of continuous intravenous infusion of nicardipine allowed tight control of hemodynamics despite impressive increases in circulating catecholamines. The mean operative time was 76 minutes (range 59-130). Blood loss was minimal. We observed neither mortality nor morbidity. Mean hospital stay ranged from 3 to 13 days (median = 3). All patients are normotensive without drug after a follow-up of 9 to 33 months. In conclusion, we think that laparoscopic removal of selected cases of pheochromocytoma may be performed safely from both the hemodynamical and oncological standpoints. [less ▲]

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See detailQuality of life as outcome in the treatment of osteoporosis : The development of a questionnaire for quality of life by the European Foundation for Osteoporosis
Lips, P; Cooper, C; Agnusdei, D et al

in Osteoporosis International (1997), 7

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See detailRheinische Wortgeographie. Karten des Rheinischen Wörterbuchs und ihre computative Auswertung. Teil II
Möller, Robert ULg

in Rheinische Vierteljahrsblätter (1997), 61

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See detailGenetic Diversity In Lima Bean (Phaseolus Lunatus L) As Revealed By Rapd Markers
Fofana, B.; Vekemans, X.; Du Jardin, Patrick ULg et al

in Euphytica (1997), 95(2),

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