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See detailThe thermospheric odd nitrogen photochemistry: role of non thermal N(4S) atoms
Shematovich, V.; Bisikalo, D.; Gérard, Jean-Claude ULg

in Geophysical Research Letters (1992), 10

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See detailCorrespondence analysis for quantification in electron energy loss spectroscopy and imaging.
Gelsema, E. S.; Beckers, Albert ULg; Sorber, C. W. et al

in Methods of Information in Medicine (1992), 31(1), 29-35

Electron energy loss spectroscopy (EELS) is a technique to investigate the physical properties of material. Using this technique it is possible to detect the presence of a specific element in a specimen ... [more ▼]

Electron energy loss spectroscopy (EELS) is a technique to investigate the physical properties of material. Using this technique it is possible to detect the presence of a specific element in a specimen. When used in combination with an electron microscope, energy filtered images may be obtained, which in principle may be used to quantify the local element concentration. This involves a process of background correction, conventionally performed assuming a specific parametric behavior of the spectral intensity as a function of electron energy loss. In this article a parameter-free method is described for background correction based on the formalism of correspondence analysis. Such a method may be used in parts of the spectrum where the functional dependence of the spectral intensity is unknown. Use of this method for element detection has been suggested before. This article reports simulation experiments suggesting its suitability for quantitative determination of element distributions and element concentrations. [less ▲]

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See detailDaily-life difficulties in person recognition reported by young and elderly subjects
Schweich, M.; Van der Linden, Martial ULg; Brédart, Serge ULg et al

in Applied Cognitive Psychology (1992), 6

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See detailLight scattering by rough surfaces: Electromagnetic model for lighting simulations
Embrechts, Jean-Jacques ULg

in Lighting Research & Technology (1992), 24(4)

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See detailImpaired immune responses in diabetes mellitus: analysis of the factors and mechanisms involved. Relevance to the increased susceptibility of diabetic patients to specific infections.
Moutschen, Michel ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Diabète & Métabolisme (1992), 18(3), 187-201

The reasons why diabetic patients present with an increased susceptibility to frequent and protracted infections remain unclear. The virtual absence of epidemiological studies of the independent risk ... [more ▼]

The reasons why diabetic patients present with an increased susceptibility to frequent and protracted infections remain unclear. The virtual absence of epidemiological studies of the independent risk factors involved contrasts with the multitude of in vitro models focused on the metabolism and function of immune cells from diabetic patients. This review analyzes some of these models and their clinical relevance. The different levels of diabetes pathogenesis: genetic (Type 1), autoimmune (Type 1) and metabolic (Type 1 and Type 2) are responsible for immune abnormalities demonstrated in in vitro models. The participation of genetic and autoimmune factors has been mainly characterized on T lymphocyte function. The B8 DR3 haplotype is associated with several minor immunologic abnormalities in vitro. However, the high frequency of this haplotype in healthy individuals argues against its involvement in significant defects of antimicrobial immunity. Genetic deficiency of C4, present in 25% of Type 1 diabetic patients could, on the other hand, be responsible for opsonization defects against encapsulated pathogens. Several immunological abnormalities related to the autoimmune process preceding the onset of Type 1 diabetes mellitus, such as the depletion of memory CD4+ cells and the defective natural killer activity could transiently impair host defences against viral diseases. Several in vitro functional defects of the immune system have been correlated with the metabolic control of diabetic patients. This suggests the involvement of insulinopenia in some of the abnormalities observed. Insulinopenia-induced enzymatic defects have often been proposed to inhibit energy-requiring functions of phagocytes and lymphocytes. However, the relevance of this mechanism could be confined to patients with extremely severe metabolic abnormalities. The importance of systemic consequences of insulinopenia such as hyperglycaemia and ketosis has also been addressed. Usually, the defects induced in vitro by these factors are slight and require supraphysiologic concentrations of glucose or ketone bodies. Recent studies have shown abnormalities of signal transduction mechanisms in which insulinopenia itself and other factors such as circulating immune complexes could be involved. Despite numerous controversies, many in vitro studies of the immune cells of diabetic patients have demonstrated significant defects which bear quantitative similarities with abnormalities described in other immunodeficiency syndromes. Furthermore, several mechanisms have been proposed to link the different defects observed with the specific infections encountered in diabetic patients. [less ▲]

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See detailHistory and Dispossession in John Glenday's Poetry
Pagnoulle, Christine ULg

in Ecosse : Littérature et Civilisation (1992), 12

This short essay discusses Glenday's poetic exploration of history, especially the tragedy of dispossession during the enclosure movement.

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See detailEngineering geological conditions in the central area of Shanghai
Schroeder, Christian ULg; Dassargues, Alain ULg; Li, Xiang Lin

in Bulletin of Engineering Geology & the Environment (1992), 46

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See detailDogmatismes sur les campus
Martiniello, Marco ULg

in Agenda Interculturel (1992), 101

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See detailColour rendering of supplementary artificial lighting
Embrechts, Jean-Jacques ULg

in Color Research and Application (1992), 17(3)

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See detailExpression of functional neurohypophysial peptide receptors by murine immature and cytotoxic T-cell lines
Martens, Henri ULg; Robert, Françoise; Geenen, Vincent ULg et al

in Progress in NeuroEndocrinImmunology (1992), 5

In order to demonstrate the cryptocrine model of neuroendocrine-immune interactions, specific neurohypophysial (NHP) receptors were detected on murine immature pre-T and cytotoxic T cell lines. A computer ... [more ▼]

In order to demonstrate the cryptocrine model of neuroendocrine-immune interactions, specific neurohypophysial (NHP) receptors were detected on murine immature pre-T and cytotoxic T cell lines. A computer analysis (LIGAND) revealed the heterogeneity of the binding sites. The Kd of Highest affinity were equivalent in both cell lines (0.15 nM), but the capacity (Bmax) of both low and high affinity sites was higher in the immature thymic lymphoma-derived pre-T-cell line. The functionality of these receptors was evidenced by their transduction of NHP-related ligands as an increase in intracellular inositol phosphates. These transductory properties were inhibited by a V1 receptor antagonist in pre-T cells, and by an oxytocin (OT) receptor antagonist in cytotoxic T cells. This work supports the involvement of NHP-related ligands and receptors in a process of cryptocrine signaling in the thymus, where the peptide concentration and the receptor affinity are in appropriate concordance. [less ▲]

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See detailMourning and Guilt among Greek Women having repeated abortions
Naziri, Despina ULg; Tzavaras, Th.

in Omega : Journal of Death and Dying (1992), 26(2), 137-144

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See detailLa dépendance externe de l'appareil productif de cinq pays de la CEE
Lejeune, Bernard ULg

in Cahiers Economiques de Bruxelles (1992), 133

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See detailDéveloppement d'un Gestionnaire Automatisé de Bibliographies selon les normes de l'American Psychological Association (GABI APA Style)
Thirion, Paul ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1992), XXVIII(1-4), 251-284

Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This ... [more ▼]

Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This situation remains awkward, especially for scientists who have regularly to report references in an extremely ruled international format. GABI APA Style was built in titis context. GABl APA Style is a reference manager software using the presentation rules of the American Psychological Association (A.P.A.) It was written in Clipper language conforming to the relational database principle. The initial aim was to elaborate a software to centralize references, filling in the intellectual background of the Department od Psychology and Educational Sciences of Liège University. Special attention was paid to the ergonomic and easy-to-use aspects of the software, just as the possibilities of transfers with other applications. [less ▲]

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See detailEnergy hypersurface local properties of the O2HF-1 rearrangement
Dive, Georges ULg; Dehareng, Dominique ULg; Culot, Patrick et al

in Chemical Physics Letters (1992), 195(2-3), 189-193

This work analyses a case where Murrell's proposal, stating that a second-order point must lie above a first-order one, is apparently violated. Study at the SCF-UMP2 level within the D95 + + basis set, of ... [more ▼]

This work analyses a case where Murrell's proposal, stating that a second-order point must lie above a first-order one, is apparently violated. Study at the SCF-UMP2 level within the D95 + + basis set, of one critical point of the O2HF- anion, previously proposed to be of order two by Lopez, shows the importance of the electronic correlation. The critical point associated with the (2)PI first-order ones. The present analysis reveals that this contradistinction can be explained by three unconsidered elements: the local symmetry, the electronic correlation and the internal variables description. [less ▲]

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See detailELISA test, a new method to detect and quantify isoproturon in soil.
Liegeois, Eric; Dehon, Yves; De Brabant, Bernard et al

in Science of the Total Environment (1992), 123/124

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See detailIncidence redistributive de la privatisation des retraites
Delhausse, B.; Pestieau, Pierre ULg; Perelman, Sergio ULg

in Revue d'Economie Financière (1992), (23), 65-79

L’objet de cet article est d’étudier l’incidence redistributive que devrait avoir la substitution partielle des pensions publiques par des pensions privées, qui favorisent les salaires et les revenus les ... [more ▼]

L’objet de cet article est d’étudier l’incidence redistributive que devrait avoir la substitution partielle des pensions publiques par des pensions privées, qui favorisent les salaires et les revenus les plus élevés relativement aux salaires et revenus les plus faibles. Dans la mesure où les pensions privées vont se développer, l’article évalue si elles ne vont pas accroître les inégalités dans les tranches d’âge les plus élevées par des simulations effectuées dans le cadre de la Belgique. [less ▲]

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See detailElisa Test, A New Method To Detect And Quantify Isoproturon In Soil
Liegeois, E.; Dehon, Y.; Debrabant, B. et al

in Science of the Total Environment (1992), 123

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See detailThe couplilng of quark and gluon condensates in denses systems
Ripka, Georges; Jaminon, Martine ULg

in Annals of Physics (1992), 218

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See detailNouvelles approches pharmacologiques basées sur les interactions neuro-endocrino-immunitaires
Gueenen, V.; Franchimont, N.; Louis, Edouard ULg et al

in Médecine et Hygiène (1992), 50

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See detailEndotoxin-induced microvascular injury in isolated and perfused pig lungs
Urbain, B.; Gustin, Pascal ULg; Ansay, Michel ULg

in Veterinary Research Communications (1992), 16(6), 453-464

The lungs of 13 healthy Landrace piglets were isolated, perfused and maintained in an isogravimetric state under zone III conditions. By applying vascular occlusion methods, the total blood flow ... [more ▼]

The lungs of 13 healthy Landrace piglets were isolated, perfused and maintained in an isogravimetric state under zone III conditions. By applying vascular occlusion methods, the total blood flow resistance (Rt) was partitioned into four components: arterial (Ra), pre- (Ra') and post-capillary (Rv'), and venous (Rv). The capillary filtration coefficient (Kfc) was evaluated using a gravimetric technique. A bolus of 55 micrograms of Escherichia coli endotoxins (LPS) per 100 g of lung was injected into the arterial reservoir of eight lungs, followed by an infusion of LPS at a rate of 55 micrograms per 100 g of lung per hour for 180 min. A bolus of theophylline (85 mg per 100 g of lung weight) was injected into the arterial reservoir after the last determination of the Kfc value. All the parameters were evaluated again when the lungs reached a new steady state. Endotoxin induced a significant increase in Rt from 54.7 +/- 7.0 at zero time to 184.7 +/- 44.2 cmH2O min L-1 (100 g)-1 180 minutes later, which can be ascribed to the increase in Ra' and Rv'. These haemodynamic modifications were related to the increases in the arterial pressure and in the pressure at the distal end of the arterial segment and to the decreases in the pressure at the proximal end of the venous segment and in the blood flow. The capillary pressure and the lung weight remained unchanged. Endotoxin infusion induced an increase in the Kfc value from 0.208 +/- 0.011 (at t = 0) to 0.391 +/- 0.034 ml min-1 (cmH2O)-1 (100 g)-1 (at t = 180). Administration of theophylline significantly reduced Rt,Ra,Ra' and Rv' towards or under the baseline values and also induced a significant increase in the lung weight and in the Kfc value. It was concluded that the endotoxin-induced increase in the total blood flow resistance can be ascribed to a vasospasm occurring at the level of the pre- and post-capillary small vessels and that changes in the permeability of the endothelium greatly contribute to the development of the pulmonary oedema observed in endotoxaemic pigs [less ▲]

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See detailIntraoperative cytokines production during orthotopic liver transplantation
Pirenne, J.; Noizat-Pirenne, F.; De Groote, D. et al

in Transplant International : Official Journal of the European Society for Organ Transplantation (1992), 5(Suppl 1), 631-635

In summary, we established that a significant production of the monokines interleukin-6, tumor necrosis factor apha, and interleukin-1 occurred during orthotopic liver transplantation whereas the ... [more ▼]

In summary, we established that a significant production of the monokines interleukin-6, tumor necrosis factor apha, and interleukin-1 occurred during orthotopic liver transplantation whereas the lymphokines interferon gamma and interleukin-2 were not detected. Levels of interleukin-6 reached their maximum values before and especially at the end of the anhepatic phase. They remained high after the anhepatic phase, i. e. after reperfusion of the new livers. Tumor necrosis factor alpha and interleukin-1 reached their maximum values after the anhepatic phase. Not only were interleukin-6, tumor necrosis factor alpha, and interleukin-1 present in the serum but they could also be detected in the bile produced by these new livers. Mechanisms of monokine production during orthotopic liver transplantation is multifactorial in origin and further studies will have to evaluate the relative contribution of the various factors involved. The possibility of an association between peroperative monokines and transplant outcome and their potential clinical implication will have to be elucidated. [less ▲]

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See detailIntroductions et Réintroductions de mammifères en Belgique: Bilan et réflexions
Libois, Roland ULg

in Annales biologiques du Centre (1992), 4

During the last century, five mammal species were introduced into Belgium. One of them, the wild sheep, was introduced by hunters. Illicite releases are responsable of the presence of the coypu in many ... [more ▼]

During the last century, five mammal species were introduced into Belgium. One of them, the wild sheep, was introduced by hunters. Illicite releases are responsable of the presence of the coypu in many localities and the Siberian chipmunk in the vicinity of Brussels. The muskrat, widespread all over the country, the raccoon and some coypus are invaders from rearing facilities. Population reinforcements of game species (brown hare, red deer, wild boar...) are still frequent and are made without any control measures. Sometimes, hybrids between domestic pigs and wild boars are released in the wild by hunters. No project is officially supported to reintroduce extinct species. In some conservationist groups, however, there is some concern in doing something in favor of the otter and the beaver. [less ▲]

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See detailFibromuscular dysplasia of the external iliac artery. A case report.
ADANT, JEAN-PHILIPPE; SAKALIHASAN, Natzi ULg; Dekoster, Guy ULg et al

in Vascular Surgery (1992), 26

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See detailLa matière en suspension de la couche de surface du plateau continental nord-ouest européen. I. Distribution spatiale de la biomasse et du rapport 13C/12C
Dauby, Patrick ULg; Mosora, Fiorentina; Frankignoulle, Michel et al

in Bulletin de la Société Royale des Sciences de Liège (1992), 61

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See detailEvidence for the expression of growth hormone receptors in human placenta
Frankenne, Francis; Alsat, Eliane; Scippo, Marie-Louise ULg et al

in Biochemical and Biophysical Research Communications (1992), 182(2), 481-486

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See detailMeasuring Technical Efficiency in European Railways: A Panel Data Approach
Gathon, Henry-Jean ULg; Perelman, Sergio ULg

in Journal of Productivity Analysis (1992), 3

We estimate a factor requirement frontier for European railways using a panel data approach in which technical efficiency is assumed to be endogencously determined. This approach has two main outcomes. On ... [more ▼]

We estimate a factor requirement frontier for European railways using a panel data approach in which technical efficiency is assumed to be endogencously determined. This approach has two main outcomes. On one hand, it allows the identification of factors influencing technical efficiency, and on the other hand, it allows the estimation of alternative efficiency indicators free of these influences. In the case under study, a particular attention is devoted to an autonomy indicator representing the managerial freedom, with respect to public authorities, experienced by firms, that appears to be positively correlated with technical efficiency. [less ▲]

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See detailEnquête sur l'infestation du renard roux (Vulpes vulpes) par Echinococcus multilocularis en province de Luxembourg (Belgique)
Brochier, B.; Coppens, P.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailBiotechnologies et agriculture: impact et perspectives.
Semal, J.; Lepoivre, Philippe ULg

in Cahiers Agricultures (1992), 1(3),

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See detailInheritance and wealth composition
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Journal of Population Economics (1992), (5), 305-318

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French ... [more ▼]

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French households. The main conclusion is that bequest motives indeed influence the composition of households' wealth. However, available data does not allow one to sort out the influence of specific models of inheritance. [less ▲]

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See detailSquatting to standing: an unusual but powerful postural manoeuvre to investigate human arterial blood pressure regulation
Pochet, T. F. J.; Gérard, Paul; Fossion, Anny et al

in Archives of Physiology & Biochemistry (1992), 100(5), 31-51

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See detailMéthodologie de réalisation du schéma de structure communal en Région wallonne : Comptes rendus d'expériences, les communes de Fléron et de Dison
Collette, Jean-Pierre ULg; Goossens, Marc ULg; Hanocq, Philippe ULg

in Environnement et Société (1992), 9/10

Présentation des démarches qui ont été suivies pour réaliser les schémas de structure des communes de Fléron et de Dison et réflexions générales suscitées par ces deux expériences.

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See detailMetabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy.
Joris, Jean ULg; Cigarini, I.; Legrand, Marc ULg et al

in British Journal of Anaesthesia (1992), 69(4), 341-5

We have compared metabolic and respiratory changes after laparoscopic cholecystectomy (n = 15) with those after open cholecystectomy (n = 15). The durations of postoperative i.v. therapy, fasting and ... [more ▼]

We have compared metabolic and respiratory changes after laparoscopic cholecystectomy (n = 15) with those after open cholecystectomy (n = 15). The durations of postoperative i.v. therapy, fasting and hospital stay were significantly shorter in the laparoscopy group. During the first and second days after operation, analgesic consumption but not pain scores (visual analogue scale) were significantly smaller after laparoscopy, while vital capacity, forced expiratory volume in 1 s, and PaO2 were significantly greater. The metabolic and acute phase responses (glucose, leucocytosis, C-reactive protein) were less after laparoscopy compared with laparotomy. Although plasma cortisol and catecholamine concentrations were not significantly different between the two groups, after surgery interleukin-6 concentrations were less in the laparoscopy group. [less ▲]

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See detailDynamic changes in the density of radial glial fibres of the developing murine cerebral wall: A quantitative immunohistochemical analysis
Gadisseux, Jean-François; Evrard, Phlippe; Misson, Jean-Paul ULg et al

in Journal of Comparative Neurology (The) (1992), 321

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See detailReversed-Phase Hptlc Densitometric Evaluation of Fraxin in Fraxinus Excelsior Leaves
Poukens-Renwart, P.; Tits, Monique ULg; Wauters, Jean-Noël ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (1992), 10(10-12, Oct-Dec), 1089-91

The present work describes a rapid and selective assay for fraxin based on its characteristic fluorescent properties by densitometry on reversed-phase HPTLC plates. Two chromatographgic procedures ... [more ▼]

The present work describes a rapid and selective assay for fraxin based on its characteristic fluorescent properties by densitometry on reversed-phase HPTLC plates. Two chromatographgic procedures (Silicagel and RP 18) have been assessed and the results compared to those obtained by reversed-phase HPLC on ODS-silica. The amount of fraxin found in six commercial batches of Fraxinus excelsior leaves ( based on dry weight) ranged from 0.1 to 0.2%. [less ▲]

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See detailCanzoni di Crociata.
Moreno, Paola ULg

in Medioevo Romanzo (1992)

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See detailLight and electron microscopic immunolocalization of bovine pregnancy-associated glycoprotein in the bovine placentome.
Zoli, A.; Demez, Pierre ULg; Beckers, Jean-François ULg et al

in Biology of Reproduction (1992), 46(4), 623-9

A bovine pregnancy-associated glycoprotein (bPAG) of 67 kDa has previously been isolated from bovine fetal cotyledons. The objective of this study was to determine the cytological localization of that ... [more ▼]

A bovine pregnancy-associated glycoprotein (bPAG) of 67 kDa has previously been isolated from bovine fetal cotyledons. The objective of this study was to determine the cytological localization of that protein in the placentomes and possibly the cells responsible for its production. Highly specific antisera raised against pure bPAG were used to demonstrate the cellular localization of the protein in bovine placentomes by light and electron microscopic techniques. Strong immunostaining was observed exclusively in the cytoplasm of large binucleate cells present predominantly in fetal cotyledonary tissue (villi). Some smaller weakly immunostained cells were also present in caruncular epithelium. By ultrastructural immunogold procedures, the protein was detected only within amorphous cytoplasmic granules. Granules of identical size, but weakly labeled, were found on the maternal side. All cells containing labeled granules were binucleate. These results suggest that bPAG is probably synthesized by trophoblast binucleate cells and stored in granules prior to delivery into the maternal circulation after cell migration. [less ▲]

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See detailCompte rendu de J.L. NELSON, Politics and Ritual in Early medieval Europe
Marchandisse, Alain ULg

in Moyen Age (Le) (1992), 98

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See detailInverse modulation of steady-state messenger RNA levels of two non-integrin laminin-binding proteins in human colon carcinoma.
Castronovo, Vincenzo ULg; Campo, E.; van den Brule, F. A. et al

in Journal of the National Cancer Institute (1992), 84(15), 1161-9

BACKGROUND: Interactions between cells and the basement membrane glycoprotein laminin are altered during colon cancer progression. Colon carcinoma and normal mucosa cells express a variety of laminin ... [more ▼]

BACKGROUND: Interactions between cells and the basement membrane glycoprotein laminin are altered during colon cancer progression. Colon carcinoma and normal mucosa cells express a variety of laminin-binding proteins, including the 67-kd laminin receptor (67 LR) and a 31-kd human laminin-binding protein (HLBP31) homologous to the 31-kd human IgE-binding protein/galactoside-binding lectin. PURPOSE: To investigate whether various laminin-binding proteins are differentially expressed in human colon carcinoma, we studied messenger RNA (mRNA) levels of the 67 LR and HLBP31 in matched tumor and adjacent normal mucosa samples from a series of 21 patients. METHODS: Total cellular RNA from tumor and normal mucosa was isolated and analyzed by Northern and slot blot hybridization. In addition, HLBP31 protein levels were assessed by the immunoblot technique. Quantitative laminin affinity chromatography was also used to measure the synthesis of HLBP31 protein in five human cancer cell lines. RESULTS: The steady-state mRNA level of HLBP31 was downregulated (i.e., decreased) in 18 of 21 human colon carcinomas compared with the level in their corresponding normal colonic mucosa. On average, the level of HLBP31 mRNA was decreased 50% +/- 30% (+/- SD) in the colon cancers. The mean ratio of colon cancer HLBP31 mRNA to adjacent normal mucosa HLBP31 mRNA was twofold lower in primary tumors of patients with metastases (0.3 +/- 0.2 SD) than in primary tumors of patients free of metastatic lesions (0.6 +/- 0.2 SD). The differences between the two groups of patients were statistically significant (P less than .05, Wilcoxon-Mann-Whitney test). We have previously shown that the ratio of colon cancer 67 LR mRNA to corresponding normal mucosa 67 LR mRNA was increased in the same patient population. When the two ratios (ratio of cancer to normal HLBP31 mRNA and ratio of cancer to normal 67 LR mRNA) were compared, HLBP31 mRNA/67 LR mRNA was significantly lower (P less than .05) in primary tumors with metastases (mean +/- SD, 0.3 +/- 0.2) than in primary cancers without metastases (mean +/- SD, 0.7 +/- 0.5). The steady-state level of HLBP31 mRNA was directly correlated with the amount of HLBP31 protein in both colon tissue samples and human cancer cell lines. CONCLUSION: HLBP31 mRNA expression in colon cancer tissues is modulated inversely to that of 67 LR mRNA expression. The down-regulation of HLBP31 appears to be associated with the metastatic capabilities of colon cancer cells. IMPLICATIONS: Prospective studies on a large cohort should determine if the systematic detection of HLBP31 and 67 LR protein and/or mRNA can be a valuable adjunct in the prognostic evaluation of primary colon cancers. [less ▲]

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See detailStructure biogeographique des peuplements et traits d'histoire naturelle des Carabides en Belgique.
Dufrêne, Marc ULg; Legendre, P.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), 35

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See detailExtracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to appearance of early markers of tumor progression.
Tennenbaum, T.; Yuspa, S. H.; Grover, A. et al

in Cancer Research (1992), 52(10), 2966-76

Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer ... [more ▼]

Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer. Using the techniques of immunohistochemistry and immunofluorescence, we show that cell-matrix interactions via the cell surface integrin receptors alpha 3 beta 1, alpha 5 beta 1, alpha 6 beta 4, the Mr 67,000 laminin receptor (67LR) laminin-binding protein, and the secreted matrix protein laminin are strictly regulated during differentiation of mouse epidermis. While alpha 6 beta 4 and alpha 5 beta 1 are polarized to the basal surface of basal cells in contact with the basement membrane, alpha 3 beta 1 and the non-integrin 67LR are primarily detected in the cell periphery of suprabasal cells, where cell to cell contacts are found. Sequential changes in expression of matrix receptors occur following multistage carcinogenesis of mouse skin. In an analysis of benign and malignant skin tumors induced by chemical carcinogens or oncogene transduction, we found that alpha 3 beta 1 and alpha 5 beta 1 as well as the non-integrin 67LR are sequentially down-regulated in the progression from benign to malignant, while alpha 6 beta 4 is the predominant receptor expressed in the carcinomas. Tumor expression of alpha 6 beta 4 is not polarized and is dissociated from its colocalized normal partner bullous pemphigoid antigen, which remains restricted to the basement membrane. The changes in matrix receptors are linked to appearance of keratin 13 in suprabasal regions, but always in alpha 6 beta 4 negative cells. The predominance of alpha 6 beta 4 in the proliferating cells during progression is associated with decreased expression of keratin 13 in carcinomas. These results suggest that matrix interactions with its receptors are important determinants of ordered differentiation in normal skin and show characteristic alterations during carcinogenesis that parallel changes in differentiation of the tumors. [less ▲]

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See detailEvaluation des méthodes de contrôle des anabolisants dans le cadre des décisions européennes
Willemart, Jean-Pierre; Scippo, Marie-Louise ULg; Gaspar, Pol et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailLe traitement des prolactinomes par un nouvel agoniste dopaminergique (le CV 205-502) : résultats chez 48 patients.
Beckers, Albert ULg; Ghuysen, A. E.; Abs, R. et al

in Médecine et Hygiène (1992), 50

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See detailL'explication en Ethologie : quelques essais de modélisation - L'exemple des poissons.
Poncin, Pascal ULg; Ruwet, J. C.

in Probio revue (1992), 10(1-2), 71-82

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See detailCaractérisation du sol vis-à-vis de l'assainissement.
Debbaut, Vincent ULg

in Tribune de l'Eau (La) (1992), 45(560), 57-66

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See detailIntérêts et procédure d'ordre, obs. sous comm. Charleroi, 6 novembre 1991
Biquet, Christine ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1992)

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See detailA gel retardation assay system for studying protein binding to simple repetitive DNA sequences.
Maueler, W.; Muller, Marc ULg; Kohne, A. C. et al

in Electrophoresis (1992), 13(1-2), 7-10

Simple repetitive DNA sequences have been regarded as mere "junk" present in all eukaryotic genomes. In fact, mixed simple repeat (gt)n(ga)m sequences are present in major histocompatibility complex MHC ... [more ▼]

Simple repetitive DNA sequences have been regarded as mere "junk" present in all eukaryotic genomes. In fact, mixed simple repeat (gt)n(ga)m sequences are present in major histocompatibility complex MHC-DRB genes for long evolutionary times, including such distant animals as artiodactyla and man. We describe herein an unsophisticated method which reveals that at least certain simple repetitive (gt)n(ga)m sequences bind nuclear proteins and show characteristics of a specific DNA-protein interaction via gel retardation. [less ▲]

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See detailModélisation mathématique des aquifères
Dassargues, Alain ULg; Monjoie, Albéric ULg

in Bulletin d'Information de l'ANSEAU (1992)

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See detailTravail de montage d'ascenseurs et plaintes musculosquelettiques
Collas, Françoise; Mairiaux, Philippe ULg

in Archives des Maladies Professionnelles de Médecine du Travail et de Sécurite Sociale (1992), 53(6), 407-413

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See detail"Arterialization", "revascularization" , "rearterialization" - what's in a name?
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULg et al

in Transplant International (1992), (5), 121-122

See detailVaricella-zoster virus: an ultrastructural study of the assembly phases
Schoonbroodt, Sonia; Piette, Jacques ULg; Rentier, Bernard ULg

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

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See detailDonnées récentes sur la biologie moléculaire du pestivirus responsable de la maladie des muqueuses (BVD/MD)
Boulanger, D.; Mignon, Bernard ULg; Waxweiler, S. et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailDiagenèse des monticules micritiques de la partie supérieure du Frasnien du Synclinorium de Dinant (Belgique, France)
Boulvain, Frédéric ULg; Herbosch, A.; Keppens, E.

in Comptes Rendus de l'Académie des Sciences. Série II, Mécanique, Physique, Chimie, Sciences de l'Univers, Sciences de la Terre (1992), 315

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See detailMri-Pathological Correlations in Acute Traumatic Central Cord Syndrome: Case Report
Martin, Didier ULg; Schoenen, Jean ULg; Lenelle, Jacques ULg et al

in Neuroradiology (1992), 34(4), 262-6

Ante- and post-mortem MRI and detailed pathological examination were performed in a patient with a typical acute traumatic central cord syndrome (ATCCS) after a minor hyperextension injury to the neck who ... [more ▼]

Ante- and post-mortem MRI and detailed pathological examination were performed in a patient with a typical acute traumatic central cord syndrome (ATCCS) after a minor hyperextension injury to the neck who died 60 h later from heart failure. T2-weighted MRI showed a central hyperintense area at C3-4. There were disc protrusions, but no vertebral fracture or displacement. Histopathology disclosed severe axonal swelling and oedema in the dorsolateral fasciculi and, to a lesser degree, in the dorsal columns. In addition, an area of recent necrosis was found in the right anterior horn at C4-5. These findings suggest that the pathological hallmark of typical ATCCS is mechanical axonal disruption at a segmental level, but that more severe trauma may be accompanied by tissue destruction. [less ▲]

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See detailPRELIMINARY-RESULTS OF 3-D BAROCLINIC NUMERICAL-MODELS OF THE MESOSCALE AND MACROSCALE CIRCULATIONS ON THE NORTH-WESTERN EUROPEAN CONTINENTAL-SHELF
Delhez, Eric ULg; Martin, Géraldine ULg

in Journal of Marine Systems (1992), 3(4-5), 423-440

Two mathematical models for the study of mesoscale (tides, storm surges ...) and macroscale (general circulation ...) motions are described. Both models are derived from the GHER 3-D baroclinic turbulent ... [more ▼]

Two mathematical models for the study of mesoscale (tides, storm surges ...) and macroscale (general circulation ...) motions are described. Both models are derived from the GHER 3-D baroclinic turbulent closure primitive equation model and adapted to the specific spectral windows of, respectively, mesoscale and macroscale processes. Numerical methods are discussed: 3-D finite differences, mode-splitting, sigma-transform ... The mesoscale model is applied to the simulation of the M2 tide on the North-Western European Continental Shelf. The residual circulation model is based on time averaged primitive equations which explicitly include mesoscale Reynolds stresses that are computed by the mesoscale model. Preliminary results of the application of this model in typical summer conditions are presented. [less ▲]

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See detailRaisonnements naturels en hydrodynamique
Blondin, Christiane ULg; Lafontaine, Dominique ULg; Closset, Jean-Louis ULg

in Revue Française de Pédagogie (1992), 100

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See detailLocation and Characterization of the Bovine Herpesvirus Type 4 Thymidine Kinase Gene; Comparison with Thymidine Kinase Genes of Other Herpesviruses
Lomonte, P.; Bublot, M.; Pastoret, Paul-Pierre ULg et al

in Archives of Virology (1992), 127(1-4), 327-37

The location and nucleotide sequence of the bovine herpesvirus type 4 (BHV-4) thymidine kinase (TK) gene was determined. The coding region of the TK gene is 1335 nucleotides long and corresponds to a ... [more ▼]

The location and nucleotide sequence of the bovine herpesvirus type 4 (BHV-4) thymidine kinase (TK) gene was determined. The coding region of the TK gene is 1335 nucleotides long and corresponds to a polypeptide of 445 amino acids. Comparison of TK amino acid sequences of BHV-4 and 16 herpesvirus TKs reveals a greater homology to those of the gammaherpesviruses EBV and specially HVS, than to those of alphaherpesviruses. The open reading frames detected in the vicinity of TK gene were homologous to the corresponding ones in other herpesviruses. [less ▲]

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See detailIn-vitro evaluation of drugs proposed as chondroprotective agents.
Bassleer, C.; Henrotin, Yves ULg; Franchimont, P.

in International Journal of Tissue Reactions (1992), 14(5), 231-41

Three proposed chondroprotective agents (CP), namely glucosamine sulfate (GAS), chondroitin sulfate (CS) and glycosaminoglycan-peptide complex (GP-C), were tested on differentiated human articular ... [more ▼]

Three proposed chondroprotective agents (CP), namely glucosamine sulfate (GAS), chondroitin sulfate (CS) and glycosaminoglycan-peptide complex (GP-C), were tested on differentiated human articular chondrocytes cultured in clusters. Chondrocyte productions of proteoglycans (PG), type II collagen (coll. II) and prostaglandin E2 (PGE2) were established by specific radioimmunoassays applied to the culture medium (CM) and in chondrocyte clusters (CC). Collagenolytic activity was assayed in CM. DNA synthesis, studied by measuring 3H-thymidine incorporation, was unaffected by CS and GAS. GP-C, at low concentration, stimulated DNA synthesis. GP-C, at higher doses, induced a high increase in PG and coll. II productions. GAS and CS induced a stimulatory effect limited to PG production. None of the CP tested here affected the basal PGE2 production by human chondrocytes. [less ▲]

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See detailTranslating poems: a precarious balance
Pagnoulle, Christine ULg

in Babel : Revue Internationale de la Traduction = International Journal of Translation (1992), 38(3), 139-148

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See detailLa cardiomyoplastie
RADERMECKER, Marc ULg; Fourny, J.; Limet, Raymond ULg

in Revue Médicale de Liège (1992), 47(3), 140-4

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See detailUne question de génétique : wallon "tchawe-sori" et français "chauve-souris"
Boutier, Marie-Guy ULg

in Travaux de linguistique et de philologie (1992), 30

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See detailEvidence for a relationship between Ehlers-Danlos type VII C in humans and bovine dermatosparaxis.
Nusgens, Betty ULg; Verellen-Dumoulin, C.; Hermanns-Le, Trinh ULg et al

in Nature Genetics (1992), 1(3), 214-7

Ehlers-Danlos (ED) syndrome type VII is characterized by the accumulation of collagen precursors in connective tissues. ED VII A and B are caused by mutations in the genes of alpha 1 and alpha 2 collagen ... [more ▼]

Ehlers-Danlos (ED) syndrome type VII is characterized by the accumulation of collagen precursors in connective tissues. ED VII A and B are caused by mutations in the genes of alpha 1 and alpha 2 collagen I which result in the disruption of the cleavage site of procollagen I N-proteinase. The existence of ED VII C in humans has been hypothesized on the basis of a disorder in cattle and sheep related to the absence of the enzyme. We now present evidence for the existence of this disease in humans, characterized by skin fragility, altered polymers seen as hieroglyphic pictures with electron microscopy, accumulation of p-N-alpha 1 and p-N-alpha 2 collagen type I in the dermis and absence of processing of the p-N-I polypeptides in fibroblast cultures. [less ▲]

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See detailCalcul des flux souterrains échangés entre le Canal Albert, la Meuse et sa plaine alluviale de Monsin à Lanaye
Dassargues, Alain ULg

in Annales de la Société Géologique de Belgique (1992), 115(1), 63-75

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See detailHighly sensitive immunodetection of DNA on sections with exogenous terminal deoxynucleotidyl transferase and non-isotopic nucleotide analogues.
Thiry, Marc ULg

in Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society (1992), 40(3), 411-9

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and ... [more ▼]

A new method is described for locating DNA on ultra-thin sections. Sections of aldehyde-fixed, plastic-embedded cells were incubated in a medium containing terminal deoxynucleotidyl transferase (TdT) and various non-isotopic nucleotide analogues. The labeled nucleotides bound to the surface of ultra-thin sections were then visualized by an indirect immunogold labeling technique. The resulting labeling pattern was strongly dependent on the divalent cation used in the TdT medium. The method revealed with great precision the specific DNA-containing structures within Ehrlich tumor cells, even where DNA was present in very low amounts. The method is compatible with all usual fixation and embedding procedures and can be combined with cytochemical methods. The in situ TdT method provides a very useful tool for pinpointing the precise location of DNA within biological material at the ultrastructural level. [less ▲]

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See detailStudy of the antagonism developped by fluorescent Pseudomonas against Pythium spp. using Tn5 and NTG mutants.
Jacques, Ph.; Mistry, C.; Ongena, Marc ULg et al

in Archives Internationales de Physiologie et de Biochimie (1992), 101(B21),

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See detailChiral theory of mesons in dense baryonic matter (I)
Jaminon, Martine ULg; Mendez Galain, Ramon; Ripka, Georges et al

in Nuclear Physics A (1992), 537

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See detailL’an un du décret de l’Aide à la jeunesse
Glowacz, Fabienne ULg; Born, Michel ULg

in Revue d’Action Sociale (1992)

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See detailThymic neuropeptides and T-cell selection
Robert, Françoise; Geenen, Vincent ULg

in Annals of the New York Academy of Sciences (1992), 650

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See detailAltered Capillary Filtration Coefficient in Parathion- and Paraoxon-Induced Edema in Isolated and Perfused Rabbit Lungs
Delaunois, Annie; Gustin, Pascal ULg; Ansay, Michel

in Toxicology and Applied Pharmacology (1992), 116(2), 161-169

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs ... [more ▼]

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs. Blood-free perfusate was recirculated through isolated and ventilated lungs in an isogravimetric state and in zone III conditions. The arterial/venous/double occlusion technique was used to divide the total vascular resistance (Rt) into four components: arterial, precapillary, postcapillary, and venous. The capillary filtration coefficient (Kfc) was evaluated by measuring the amount of fluid filtering through the endothelium when the arterial and venous pressures were suddenly increased. Pth and Pox induced pulmonary edema by increasing endothelium permeability without changing the hemodynamic parameters at any level of the vascular bed. The Kfc value increased progressively, reaching a maximum (Emax) 60 min after administration of organophosphate (558 ± 65% (n = 5) and 707 ± 109% (n = 5) of baseline values, for Pth and Pox, respectively). During the next 60 min, it decreased. The time course of Pox-induced changes in Kfc was similar to that obtained with Pth. The concentration-response curve (Emax) expressed as a percentage of the baseline value versus the logarithm of the malor Pth concentration, ranging from 2 × 10−5 to 4 × 10−4 image) was linear (y = 1661.1 + 327.3x, R = 0.89, p < 0.001, N = 14). Piperonyl butoxide (4 × 10−4 image), an inhibitor of cytochrome P450, had a strong protective effect against Pth (4 × 10−4 image)-induced alterations of endothelium permeability (n = 5, p < 0.001). The effects of Pox (4 × 10−4 image) on Kfc were completely abolished by pretreatment with 10−5 image atropine, as shown by the significantly lower Emax value recorded in atropine-pretreated lungs (129 ± 33%, n = 4) than in Pox-treated lungs (707 ± 109%, n = 5, p < 0.001). The effects of Pth, on the other hand, were only partially inhibited, since the Emax value recorded in atropine-pretreated lungs (196 ± 20%, n = 4) remained significantly higher than that recorded for control lungs (129 ± 15%; n = 5; p < 0.05). These results show that isolated and perfused rabbit lungs constitute and appropriate model for studying the direct pulmonary effects of organophosphates. The edema-inducing action of Pth depends on its activation by conversion to Pox in the lung tissue. It can be explained by an increase in endothelium permeability. This effect is mediated principally by muscarinic receptors [less ▲]

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See detailGrowth hormone response to clonidine in male untreated panic patients
Scittecatte, Michel; ANSSEAU, Marc ULg; Charles, Gerard et al

in Psychological Medicine (1992)

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See detailCompte-rendu de l'ouvrage: Archéologie en Ardenne, de la Préhistoire au XVIIIe siècle
Noiret, Pierre ULg

in Cahiers de Clio (1992), 109

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See detailPlasma myeloperoxidase and vitamin E levels in head injury: preliminary results related to outcome.
Hans, Pol ULg; Franssen, Colette ULg; Pincemail, Joël ULg et al

in Journal of Neurosurgical Anesthesiology (1992), 4(1), 26-30

This preliminary study was designed to assess a possible role of neutrophil activation and to determine the prognostic value of plasma myeloperoxidase (MPO) and vitamin E (Vit. E) levels in severe head ... [more ▼]

This preliminary study was designed to assess a possible role of neutrophil activation and to determine the prognostic value of plasma myeloperoxidase (MPO) and vitamin E (Vit. E) levels in severe head injury. Plasma MPO and Vit. E levels were measured in nine severely head-injured patients (Glasgow Coma Score </=8) (ages 12-80 years) 6, 12. 18, 24, and 30 h after trauma. Patients were classified into two groups according to outcome after discharge from the ICU: group D (death; n = 5) and group S (survival; n = 4). Plasma MPO levels were increased immediately after trauma and then decreased. The MPO peak observed after 6 h was significantly higher (p < 0.05) in group D (mean +/- SEM: 1,237 +/- 122 ng/ml) than in group S (mean +/- SEM: 543 +/- 148 ng/ml). Plasma Vit. E levels were lower than normal values and decreased over time. They were always significantly lower (p < 0.05) in group D than in group S, except for the first sample. These differences cannot be explained entirely by total plasma lipid (TL) values since no statistical difference in TL concentrations was found between the two groups during the course of study. The ratio of Vit. E to TL. considered as the best index of Vit. E status, was lower in group D than in group S. and the difference reached statistical significance (p < 0.05) 12 h after trauma. In conclusion, in spite of the limited number of patients included in this study, it appears that severe head injury is associated with an increase in MPO and a decrease in Vit. E levels. These biochemical changes are of greater magnitude in group D than in group S; they suggest neutrophil activation and lipoperoxidation processes. Finally, plasma MPO and Vit. E seem to be new discriminant factors of outcome in head-injured patients. [less ▲]

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See detailFusogenic Segments Of Bovine Leukemia-Virus And Simian Immunodeficiency Virus Are Interchangeable And Mediate Fusion By Means Of Oblique Insertion In The Lipid Bilayer Of Their Target-Cells
Voneche, V.; Portetelle, Daniel ULg; Kettmann, Richard ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (1992), 89(9),

Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis indicates ... [more ▼]

Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis indicates that (i) both BLV envelope glycoproteins gp51 and gp30 are necessary for cell fusion; (ii) insertion of the N-terminal segment of gp30 (fusion peptide) into the lipid bilayer in an oblique orientation, as predicted by computer conformational analysis, results in fusogenic capacities higher than insertion in a perpendicular or parallel orientation; and (iii) replacement of the BLV fusion peptide with its simian immunodeficiency virus counterpart does not modify the fusogenic capacity of the BLV glycoprotein. [less ▲]

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See detailLa Federation des Banques de Donnees Biogeographiques (FBDB).
Dufrêne, Marc ULg; Lebrun, Philippe; Rasmont, P.

in Mémoires de la Société Royale d'Entomologie de Belgique (1992), 35

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See detailFrom Monroe to Moreau: An analysis of face naming errors
Brédart, Serge ULg; Valentine, T.

in Cognition (1992), 45

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See detailA histologic study of the extracellular matrix during the development of glomerulosclerosis in murine chronic graft-versus-host disease.
Bergijk, E. C.; Munaut, Carine ULg; Baelde, J. J. et al

in American Journal of Pathology (1992), 140(5), 1147-56

The development of glomerulosclerosis was studied in murine chronic graft-versus-host disease (GvHD), which is a model for human systemic lupus erythematosus. The authors investigated the distribution ... [more ▼]

The development of glomerulosclerosis was studied in murine chronic graft-versus-host disease (GvHD), which is a model for human systemic lupus erythematosus. The authors investigated the distribution patterns of six components of the extracellular matrix (ECM), i.e., laminin, fibronectin, collagen types I, III, IV, and VI during the course of the disease. All of these ECM components except collagen type I were found in the glomeruli of normal mice, where all of them were intrinsic constituents of the mesangium. Laminin, fibronectin, and collagen type IV were also found in the glomerular capillary walls. Starting 6 weeks after the induction of GvHD and continuing at week 8, the onset of an expansion of the mesangial matrix was observed. At the same time, the amounts of laminin, fibronectin, and collagen types IV and VI increased. Ten weeks after the onset of the disease, glomerulosclerosis developed. Traces of the interstitial collagen type I were found in sclerotic glomeruli. The levels of four ECM components, i.e., collagens III, IV, VI, and laminin were markedly decreased in the sclerotic glomeruli as compared with week 8. In contrast, the amount of fibronectin in the sclerotic glomeruli increased dramatically. Immunoelectron microscopic examination showed fibronectin in the sclerotic lesions, in contrast to laminin, collagen type I, and collagen type IV. It is concluded that the sclerotic lesions in murine chronic GvHD contain fibronectin. The small amounts of the ECM components laminin, as well as collagens III, IV, and VI in the sclerotic glomeruli in GvHD, might represent remnants of mesangial material and collapsed capillary walls. These components are probably replaced by increased production and/or accumulation of collagen type I and fibronectin. [less ▲]

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See detailDevices for the treatment of diabetes: today.
Scheen, André ULg

in Artificial Organs (1992), 16(2), 163-6

Although single or multiple daily subcutaneous injections of insulin with syringes are the mainstay of insulin delivery techniques for the treatment of diabetes mellitus, several other methods are now ... [more ▼]

Although single or multiple daily subcutaneous injections of insulin with syringes are the mainstay of insulin delivery techniques for the treatment of diabetes mellitus, several other methods are now available. The present paper will review the main problems occurring with the classical subcutaneous insulin therapy and the possible solutions given by the use of new devices, including more particularly insulin jet injectors, pens, and portable pumps. This review has to be considered as an introduction to the presentations of this symposium devoted to implantable pumps, glucose sensors, and artificial pancreas, respectively. [less ▲]

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See detailLe désherbage mécanique, une technique d'avenir
Dardenne, J.; Dewez, G.; Vandersmissen, P. et al

in Revue de l’Agriculture = Landbouwtijdschrift (1992), 45(6), 1193-1200

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See detailDe terrae motu qui Leodii anno MDCCCXXVIII factus est
Marganne, Marie-Hélène ULg; Mélard, Marc

in Melissa (1992), 48

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See detailLa francophonie encore et toujours en question
Defays, Jean-Marc ULg

in Bulletin Francophone de Finlande (1992), (8), 3-6

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See detailAutomatic adaptive remeshing for numerical simulations of metalforming
Dyduch, M.; Habraken, Anne ULg; Cescotto, Serge ULg

in Computer Methods in Applied Mechanics & Engineering (1992), 101

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See detailL'enseignement technique agricole et le défi de l'environnement : passé et futur...
Mougenot, Catherine ULg

in Revue de l'Institut de Sociologie (1992), 1(4), 265-290

Une analyse de l’enseignement agricole technique reposant sur deux fils rouges : l’histoire de l’institution et la nécessité pour celle-ci de prendre en compte les nouvelles perspectives environnementales.

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See detailApplication de la théorie des systèmes à la thermique des bâtiments. Problèmes de modélisation, d'identification et de contrôle
Andre, Philippe ULg; Nicolas, Jacques ULg

in Revue générale de thermique (1992), 31(371), 600-615

La théorie est utilisée pour développer des modèles simplifiés, pour estimer, par des méthodes d'identification de systèmes, les variables d'état et les paramètres de ces modèles et enfin pour élaborer ... [more ▼]

La théorie est utilisée pour développer des modèles simplifiés, pour estimer, par des méthodes d'identification de systèmes, les variables d'état et les paramètres de ces modèles et enfin pour élaborer des stratégies de commande optimale pour le chauffage d'un bâtiment. L'ensemble de ces techniques est appliqué à un bâtiment solaire passif situé en Belgique. [less ▲]

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See detailGLOBOSA: a homeotic gene which interacts with DEFICIENS in the control of Antirrhinum floral organogenesis.
Trobner, W.; Ramirez, L.; Motte, Patrick ULg et al

in EMBO Journal (1992), 11(13), 4693-704

GLOBOSA (GLO) is a homeotic gene whose mutants show sepaloid petals and carpelloid stamens. The similarity of Glo mutants to those of the DEFICIENS (DEFA) gene suggests that the two genes have comparable ... [more ▼]

GLOBOSA (GLO) is a homeotic gene whose mutants show sepaloid petals and carpelloid stamens. The similarity of Glo mutants to those of the DEFICIENS (DEFA) gene suggests that the two genes have comparable functions in floral morphogenesis. The GLO cDNA has been cloned by virtue of its homology to the MADS-box, a conserved DNA-binding domain also contained in the DEFA gene. We have determined the structure of the wild type GLO gene as well as of several glo mutant alleles which contain transposable element insertions responsible for somatic and germinal instability of Glo mutants. Analyses of the temporal and spatial expression patterns of the DEFA and GLO genes during development of wild type flowers and in flowers of various stable and unstable defA and glo alleles indicate independent induction of DEFA and GLO transcription. In contrast, organ-specific up-regulation of the two genes in petals and stamens depends on expression of both DEFA and GLO. In vitro DNA-binding studies were used to demonstrate that the DEFA and GLO proteins specifically bind, as a heterodimer, to motifs in the promoters of both genes. A model is presented which proposes both combinatorial and cross-regulatory interactions between the DEFA and GLO genes during petal and stamen organogenesis in the second and third whorls of the flower. The function of the two genes controlling determinate growth of the floral meristem is also discussed. [less ▲]

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See detailRecension de l'ouvrage du Groupe Mu, "Le traité du signe visuel"
Steinmetz, Rudy ULg

in Art&Fact (1992)

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See detailCroissance de la productivité, rattrapage et innovation: une analyse des secteurs manufacturiers de l'OCDE
Fecher-Bourgeois, Fabienne ULg

in Economie et Prévision (1992), 102-103(1992-1/2), 117-127

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See detailTacuina et théorie des quatre éléments
Marganne, Marie-Hélène ULg; Lecomte, Jean

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (1992), Tome III, 6e série(1-4), 13-21

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See detailL'analyse structurale semi-rigide: définition, domaine et mode d'application
Jaspart, Jean-Pierre ULg; Maquoi, René ULg

in Infrastructuur in het Leefmilieu (1992), n°5/92

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See detailRésection hépatique ex situ
Honoré, Pierre ULg; D'Silva, Milbhor; Meurisse, Michel ULg et al

in Médecine & Chirurgie Digestives (1992), 21

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See detailLifetimes in Fe II and the solar abundance of iron
Hannaford, P.; Lowe, R. M.; Grevesse, Nicolas ULg et al

in Astronomy and Astrophysics (1992), 259

New atomic lifetimes have been determined for eight quartet (z 4D, z 4F) levels and ten sextet (z 6D, z 6F, z 6P) levels in Fe II and the results for seven of these levels have been combined with existing ... [more ▼]

New atomic lifetimes have been determined for eight quartet (z 4D, z 4F) levels and ten sextet (z 6D, z 6F, z 6P) levels in Fe II and the results for seven of these levels have been combined with existing experimental branching fractions to obtain a revised set of log gf-values for 15 solar lines in Fe II. The new log gf data are used together with equivalent widths determined from the Liege solar atlas to derive a value for the iron photospheric abundance: 7.48 +/- 0.04, which is consistent with the currently accepted meteoritic result, 7.51 +/- 0.01. The results are compared with the atomic lifetime data, log gf data and solar analyses used in three other recent solar abundance determinations based on Fe II lines. [less ▲]

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See detailStudy of a new presumed mitochondrial carrier, the product of the yeast RIM 2 gene
Hellin, E.; Van Dyck, E.; Duyckaerts, Claire ULg et al

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

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Full Text
See detailUn index sélectif d’un texte philosophique. Husserl, Die Idee der Phänomenologie
Evrard, Etienne ULg; Purnelle, Gérald ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1992)

To assist the content analysis of a philosophical text, we have created a method of constituting both a selective index reduced to philosophically significant words and several frequency lists. We have ... [more ▼]

To assist the content analysis of a philosophical text, we have created a method of constituting both a selective index reduced to philosophically significant words and several frequency lists. We have applied this method to Die Idee der Phenomenologie where Husserl explains for the first time his theory of the phenomenological reduction and of the constitution of the objects in the conscience. The results proved to be valuable for the philosophical interpretation. [less ▲]

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Peer Reviewed
See detailFrom obesity to type 2 diabetes.
Scheen, André ULg

in Acta Clinica Belgica. Supplementum (1992), 14

Obesity is a well-known risk factor for the development of non-insulin-dependent diabetes mellitus (NIDDM). Both insulin resistance and concomitant B-cell dysfunction are necessary for the development of ... [more ▼]

Obesity is a well-known risk factor for the development of non-insulin-dependent diabetes mellitus (NIDDM). Both insulin resistance and concomitant B-cell dysfunction are necessary for the development of NIDDM. Insulin resistance, probably genetically determined but worsened by obesity, appears to be the primary defect that leads to impaired glucose tolerance. However, B-cell dysfunction plays a critical role during progressive deterioration from mild impaired glucose tolerance to severe NIDDM. [less ▲]

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See detailImmunomodulatory properties of cyclic hexapeptide oxytocin antagonists
Geenen, Vincent ULg; Martens, Henri ULg; Robert, Françoise et al

in Thymus (1992), 20

A pharmacological manipulation of cryptocrine cell-to-cell signaling was tested by the investigation of the immunomodulatory properties of novel cyclic hexapeptide oxytocin (OT) antagonists (MSD Research ... [more ▼]

A pharmacological manipulation of cryptocrine cell-to-cell signaling was tested by the investigation of the immunomodulatory properties of novel cyclic hexapeptide oxytocin (OT) antagonists (MSD Research Laboratories). The compounds were found to significantly inhibit the productions of IL-1ß and IL-6 elicited by anti-CD3 treatment oh human whole blood cells cultures (WBC). Cytokine productions were more significantly reduced by OT antagonists in WBC derived from female volunteers than in those obtained from male donors, suggesting an influence of sex steroids on the expression of NHP receptors by immune cells. These observations support the concept of novel immunomodulating approaches through immune-specific neuropeptide antagonists, as well as the pharmacological value of such strategies in selective immunotherapy. [less ▲]

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