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See detailCompte rendu de Sénèque et la prose latine, (Entretiens sur l'Antiquité classique, 26), Fondation Hardt, 1991, 400 pp.
Longrée, Dominique ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1997)

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See detailMultiple pregnancy-associated glycoproteins are secreted by day 100 sheep placenta
Xie, Sancai; Green, Jonathan; Bao, Bagna et al

in Biology of Reproduction (1997), 57(6), 1384-1393

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep ... [more ▼]

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity. [less ▲]

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See detailA Direct Dopaminergic Control of Aromatase Activity in the Quail Preoptic Area
Baillien, M.; Balthazart, Jacques ULg

in Journal of Steroid Biochemistry & Molecular Biology (1997), 63(1-3, Sep-Oct), 99-113

In the quail preoptic area (POA) anatomical and pharmacological data suggest that catecholamines may be implicated in the control of testosterone (T) aromatization into estrogens. The biochemical ... [more ▼]

In the quail preoptic area (POA) anatomical and pharmacological data suggest that catecholamines may be implicated in the control of testosterone (T) aromatization into estrogens. The biochemical mechanism(s) mediating this control of the enzyme activity is (are) however unexplored. The present studies were carried out to investigate whether the catecholamines, dopamine (DA) and norepinephrine (NE) are able to directly affect aromatase activity (AA) measured during in vitro incubations of POA homogenates. AA was quantified in the POA-hypothalamus of adult male Japanese quail by measuring the tritiated water production from [1beta-3H]-androstenedione. Enzyme activity was linear as a function of the incubation time and of the protein content of homogenates. It exhibited a typical Michaelis-Menten kinetics, with an apparent Km of 2.8 nM and a Vmax of 266.6 fmol h(-1) mg wet weight(-1). AA was then measured at a substrate concentration of 25 nM in the presence of catecholamines and some of their receptor agonists or antagonists, at two concentrations, 10(-3) and 10(-6) M. Norepinephrine and prazosin (alpha1-adrenergic antagonist) had no or very limited effects on AA at both concentrations. In contrast, DA and some D1 and/or D2 receptor agonists (apomorphine[D1/D2], SKF-38393 [D1] and RU-24213 [D2]) depressed AA by 40 to 70% at the 10(-3) M concentration. One D2 receptor antagonist also produced a major inhibition of AA (sulpiride) while other antagonists either had no significant effect or only produced moderate decreases in enzyme activity (SCH-23390 [D1], spiperone [D2], pimozide [D2]) as did two DA indirect agonists, amfonelic acid and nomifensine. The inhibitory effect of the agonists was not antagonized by the less active antagonists, SCH-23390 [D1] or spiperone [D2]. Taken together these results suggest that the inhibitory effects do not involve specific binding of DA or its agonists/antagonists to dopaminergic receptors mediating changes in cAMP concentration. This conclusion is also supported by the observation that addition of dibutyryl cAMP did not change brain AA. It appears more likely that DA and dopaminergic drugs inhibit AA by a direct effect on the enzyme, as suggested by the competitive nature of DA and SKF-38393 inhibition of AA (Ki's of 59 and 84 microM, respectively). The functional significance of this effect should still be demonstrated but this mechanism may represent an important physiological pathway through which neurotransmitters could rapidly affect steroid-dependent processes such as the neural synthesis of estrogens. This would provide a mean by which environmental stimuli could affect reproductive behavior and physiology. [less ▲]

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See detailPhysical activity and cardiovascular risk factors in children. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Bjorntorp, P.

in Obesity Research (1997)

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See detailAntitumor and radiosensitizing effects of (E)-2'-Deoxy-2'-(Fluoromethylene) cytidine, a novel inhibior of ribonucleotide diphosphate reductase on human colon carcinoma xenografts in nude mice.
Sun, Lin-Quan; Li, Ye-Xiong; Guillou, Louis et al

in Cancer Research (1997), 57

Antitumor and radiosensitizing effects of (E).2'-deoxy.2'-(fluromethyl ene) cytidine (FMdC), a novel inhibitor of ribonucleotide reductase, were evaluated on nude mice bearing s.c. xenografts and liver ... [more ▼]

Antitumor and radiosensitizing effects of (E).2'-deoxy.2'-(fluromethyl ene) cytidine (FMdC), a novel inhibitor of ribonucleotide reductase, were evaluated on nude mice bearing s.c. xenografts and liver metastases of a human colon carcinoma. FMdC given once daily or twice weekly has a dose-dependent antitumor effect. The maximum tolerated dose In the mice was reached with 10 mgi'kg applied daily over 12 days. Twice weekly administration of FMdC reduced its toxicity but lowered the antitumor effect. Treatment of preestablished liver micrometastases obtained via intrasplenic injection of tumor cells, with 5 or 10 mgfkg FMdC, signifi candy prolonged the survival of the mice as compared to controls (P < 0.025 and P < 0.001, respectively). Ten mg/kg resulted in longer survival than S mg/kg FMdC (P < 0.05). Radiotherapy alone of s.c. xenografts (10 fractions over 12 days) yielded the radiation dose required to produce local tumor control in 50% of the treated mice (TCD@O)of 43.0 Gy. When combined with FMdC, TCDsawas reduced to 22.5 and 19.0 Gy at doses of 5 and 10 mg/kg given i.p. 1 h before each irradiation, respec tively. The corresponding enhancement ratios were 1.91 and 2.43, respec lively. FMdC produced moderate and reversible myelosuppression. When 5 mg/kg FMdC was combined with irradiation, there was no increased skin or hematological toxicity as compared to radiotherapy or FMdC alone. At the 10 mg/kg level, however, lower leukocyte counts were observed. These results show that FMdC appears to be a potent anticancer drug and radiosensitizer [less ▲]

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See detailBeam-laser measurements and relativistic Hartree-Fock calculations of the lifetimes of the 3d94p levels in Cu II
Pinnington, E. H.; Rieger, G.; Kernahan, J. A. et al

in Canadian Journal of Physics (1997), 75

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See detailSynthesis of resorcinol-formaldehyde aeroels by the freeze-drying methods
Mathieu, Bernard; Michaux, Bernard; Pirard, René ULg et al

in Annales de Chimie Science des Materiaux (1997), 22

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See detailLong-wavelength behavior of the exchange-correlation kernel in the Kohn-Sham theory of periodic systems
Ghosez, Philippe ULg; Gonze, X.; Godby, R. W.

in Physical Review. B : Condensed Matter (1997), 56(20), 12811-12817

The polarization dependence of the exchange-correlation (re) energy functional of periodic insulators within Kohn-Sham (KS) density-functional theory requires a O(1/q(2)) divergence in the re kernel for ... [more ▼]

The polarization dependence of the exchange-correlation (re) energy functional of periodic insulators within Kohn-Sham (KS) density-functional theory requires a O(1/q(2)) divergence in the re kernel for small vectors q. This behavior, exemplified for a one-dimensional model semiconductor, is also observed when an insulator happens to be described asa KS metal, or vice versa. Although it can occur in the exchange-only kernel, it is not found in the usual local, semilocal, or even nonlocal approximations to KS theory. We also show that the test-charge and. electronic definitions of the macroscopic dielectric constant differ from one another in exact KS theory, but are equivalent in the above-mentioned approximations. [less ▲]

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See detailTricho-hepato-enteric syndrome: further delineation of a distinct syndrome with neonatal hemochromatosis phenotype, intractable diarrhea, and hair anomalies.
Verloes, A.; Lombet, J.; Lambert, Yves ULg et al

in American Journal of Medical Genetics (1997), 68(4), 391-5

We report on two sibs with syndromal congenital iron storage disease. Prenatal symptoms were IUGR, hydramnios, and placental hyperplasia. Clinical anomalies included hypertelorism and sparse, thin, curly ... [more ▼]

We report on two sibs with syndromal congenital iron storage disease. Prenatal symptoms were IUGR, hydramnios, and placental hyperplasia. Clinical anomalies included hypertelorism and sparse, thin, curly hair (trichomalacia). Clinical course was marked by intractable diarrhoea, with normal histological and enzymological studies, cholestatic jaundice, hepatomegaly appearing after 30 days, and progressive liver failure, leading to death after a few months. The only metabolic anomaly was progressive hypermethioninemia. Pathologic examination of both children showed a similar pattern of multivisceral iron deposit compatible with a diagnosis of neonatal hemochromatosis: extensive liver fibrosis or cirrhosis with nodular regeneration, cholestasis, ductular proliferation, and hepatic, pituitary, thyroidal, adrenal, and pancreatic iron deposition. The unusual course for neonatal hemochromatosis in both sibs combined with concordant extrahepatic anomalies suggest that they could have a specific iron storage syndrome with possible autosomal recessive inheritance, probably similar to the sibship reported by Stanckler et al. [Arch Dis Child, 57:212-216, 1982]. [less ▲]

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See detailPotential of Varicella zoster virus thymidine kinase as a suicide gene in breast cancer cells
Grignet, Christine ULg; Calberg-Bacq, Claire-Michelle

in Gene Therapy (1997), 4

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See detailSm-Nd signature of modern and late Quaternary sediments from the northwest North Atlantic: Implications for deep current changes since the Last Glacial Maximum
Innocent, C.; Fagel, Nathalie ULg; Stevenson, Ross et al

in Earth & Planetary Science Letters (1997), 146(3-4), 607-625

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in ... [more ▼]

Nd isotopes and Sm-Nd concentrations have been investigated in the clay size fraction of surface and late Quaternary sediments of the northern North Atlantic. Four sources of Nd have been identified in the surface sediments: (1) a radiogenic Nd typical of the Iceland volcanism; (2) a ''Pan-African'' Nd issued from eastern Greenland; (3) a ''Variscan'' Nd derived from the Arctic Ocean; (4) an old unradiogenic Nd related to the North American Shield, In the Iceland and Irminger basins, the major sources of Nd are the Variscan Nd derived from the Arctic Ocean and the Iceland Nd, except in the western Irminger Basin where the Pan-African Nd originating from eastern Greenland is dominant and labels sedimentary supplies linked to the Denmark Strait Overflow Water, Nd derived from Icelandic volcanism is never clearly dominant, even on the Reykjanes Ridge, and the Nd derived from the American Shield becomes dominant only in the Labrador Sea, Sediments lying in the pathway of the Western Boundary Undercurrent have Nd isotopic compositions which are shifted towards more radiogenic values indicating an input of material from the eastern basins, carried by this deep current. Late Quaternary sediments were cored from the southern Greenland Rise (core 90-013-013) and eastern Labrador Rise (Orphan Knell; core 91-045-094). In core 90-013-013, epsilon Nd values during the Last Glacial Maximum are as low as -20, but subsequently rose to -9 in the modern sediments, indicating that the sedimentary material during the Last Glacial Maximum was dominated by unradiogenic Nd from the North American Shield. This may be related to a lesser outflow of the Western Boundary Undercurrent, In core 91-045-094, located along the Labrador Current trajectory, a dominant supply of North American Shield Nd is recorded, perhaps originating at least partially from the Hudson Strait, The Sm-Nd data are compatible with smectite vs. illite studies at the same sites which suggest a continuous but more modest Western Boundary Undercurrent supply during Last Glacial Maximum. [less ▲]

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See detailMetacognitive realism : A cognitive style or a learning strategy ?
Jans, Véronique; Leclercq, Dieudonné ULg

in Educational Psychology (1997), 17(1-2), 101-110

Learning implies the learner's ability to make a series of decisions and, in particular, the capacity to assess the quality and reliability of one's own knowledge incapsulated in the question: 'How far do ... [more ▼]

Learning implies the learner's ability to make a series of decisions and, in particular, the capacity to assess the quality and reliability of one's own knowledge incapsulated in the question: 'How far do I already know the content I am supposed to learnt?' The authors address the following issues: (1) Is realism in metacognition a stable trait in learners?; (2) If not, by what is it influenced?. After a short review of the literature on the topic and the examination of experimental evidence, metacognition is considered as both a style and a strategy. The need for a taxonomy of metacognitive realism is demonstrated in order to clarify the topic and to facilitate applied research. [less ▲]

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See detailCompte rendu de L.C. Youtie, P. Michigan 17. The Michigan Medical Codex (P. Mich. 758 = P. Mich. inv. 21), Atlanta, 1996 (American Studies in Papyrology, 35)
Marganne, Marie-Hélène ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), 72

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See detailToxicological investigations on four sperm whales stranded on the Belgian coast: inoganic contaminants
Bouquegneau, Jean-Marie ULg; Debacker, Virginie ULg; Gobert, Sylvie ULg et al

in Bulletin de l'Institut Royal des Sciences Naturelles de Belgique. Sciences de la Terre (1997), 67

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See detailRyle et la phénoménologie
Leclercq, Bruno ULg

in Recherches Husserliennes (1997), 7

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See detailIron management in patients on rHuEpo
Cavill, I.; Macdougall, I. C.; Gokal, R. et al

in British Journal of Renal Medicine (1997), 2

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See detailPropriétés des profils de flux d'induction magnétique dans les céramiques supraconductrices
Vanderbemden, Philippe ULg

in Bulletin Scientifique de l'Association des Ingénieurs Electriciens sortis de l'Institut Electrotechnique Montefiore (1997), 2

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See detailInfluence of dominance relationships on the estimation of dominance variance with sire-dam subclass effects
Gengler, Nicolas ULg; VanVleck, L. D.; MacNeil, M. D. et al

in Journal of Animal Science (1997), 75(11), 2885-2891

Two data sets from the USDA Livestock and Range Research Laboratory mere analyzed to study dominance variance and the influence of dominance relationships. The first consisted of 4,155 birth weight (3,884 ... [more ▼]

Two data sets from the USDA Livestock and Range Research Laboratory mere analyzed to study dominance variance and the influence of dominance relationships. The first consisted of 4,155 birth weight (3,884 weaning weight) records of inbred USDA Line 1 Herefords. The second consisted of 8,065 birth weight (7,380 weaning weight) records from a line-cross experiment with five lines. Two models were used. Both included fixed effects of year-sex of calf and age of dam, and covariates for calving date, inbreeding of animal, and inbreeding of dam. For the second set, additional covariates were line composition and heterozygosity coefficients. Random effects were direct and maternal additive genetic, maternal permanent environment, sire-dam subclass, and residual. Model 1 considered sire-dam subclasses unrelated. Model 2 related sire-dam subclasses with a parental dominance relationship matrix. Variance components were estimated using REML. Differences between estimates with Model 1 and 2 were unimportant except for dominance variance. For the first data set, estimates with Model 2 of relative genetic direct and maternal variances, direct-maternal correlation, permanent environment, and dominance variances for birth weight were .35, .13, -.02, .03, and .25, respectively, and they were .39, .11, .04, .06 and .14 for the second data set. For weaning weight, the first data set estimates were .20, .15, -.37, .19, and .11, respectively, and they were .16, .20, -.07, .18, and .18 for the second data set. Changes, decreases and increases, in estimates of dominance variances may be due to increased information from relationships and family types other than full-sibs. The assumption of unrelated sire-dam subclasses might not be appropriate for estimation of dominance variance in populations with many dominance relationships among siredam classes. [less ▲]

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See detailAssociative chunk strength in artificial grammar learning
Meulemans, Thierry ULg; Van der Linden, Martial ULg

in Journal of Experimental Psychology. Learning, Memory & Cognition (1997), 23(4), 1007-1028

In four experiments, adherence to grammatical rules and associative chunk strength (including different measures, each calculated on the basis of the frequency with which bigrams and trigrams present in ... [more ▼]

In four experiments, adherence to grammatical rules and associative chunk strength (including different measures, each calculated on the basis of the frequency with which bigrams and trigrams present in the test strings appeared in the learning strings) were manipulated independently in the test phase of an artificial grammar learning task. When participants learned few items of the grammar (Experiments 1a and 2a), the associated items were more often classified as grammatical than the nonassociated ones. On the other hand, when the learning phase included most of the grammatical items (Experiments 1b and 2b), the only effect observed was an effect of grammaticality. These results suggest that, depending on the specific constraints of the tasks, knowledge based on bigrams and trigrams and knowledge based on the abstraction of the grammatical structure can be used for the classification task. [less ▲]

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See detailEtude de la taille des nanoparticules après incorporation dans des sphéroïdes gastrorésistants
Duvivier, F; Grandfils, Christian ULg; Léonard, F et al

in Journal de Pharmacie de Belgique (1997), 52(3), 123

Nanoparticles can be used as an attractive carrier for the controlled delivery of drugs by the oral route. This nanoparticular delivery system can protect an active ingredient from enzymatic degradations ... [more ▼]

Nanoparticles can be used as an attractive carrier for the controlled delivery of drugs by the oral route. This nanoparticular delivery system can protect an active ingredient from enzymatic degradations and enhance its absorption from the intestinal mucosa. We studied the development of a gastroresistant dosage form for the oral administration of nanoparticles. Fast disintegrating pellets were used for the administration of nanoparticles and for their transit to the site of absorption. A gastroresistant film was applied onto the pellets to protect the nanoparticles and/ or the active substance from the acid gastric environment. The integrity of the nanoparticle size was assessed after two critical manufacturing steps: the extrusion/spheronisation process and the coating process. The determination of the nanoparticles size distribution was performed by photon correlation spectroscopy (PCS). The comparison of the PCS results between the original nanoparticles and the nanoparticles incorporated in the pellets shows a very low aggregation. Moreover the coating process was not a critical step since it was not responsible for an additional agglomeration of the nanoparticles. In conclusion, our manufacturing process allows the redispersion of the nanoparticles with a little change of the size distribution. In a next study we well try to quantify the release of the nanoparticles from the pellets. [less ▲]

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See detailLe cas clinique du mois, A propos d'un cas de myelinolyse centropontique chez un éthylique chronique
Lebrun, F.; Lambermont, Bernard ULg; Ghuysen, Alexandre ULg et al

in Revue Médicale de Liège (1997), 52(1), 7-11

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See detailPredictions in overdispersed series of counts using an approximate predictive likelihood
Lambert, Philippe ULg

in Journal of Forecasting (1997), 16

The generalized autoregression model or GARM, originally used to model series of non-negative data measured at irregularly spaced time points (Lambert, 1996a), is considered in a count data context. It is ... [more ▼]

The generalized autoregression model or GARM, originally used to model series of non-negative data measured at irregularly spaced time points (Lambert, 1996a), is considered in a count data context. It is first shown how the GARM can be expressed as a GLM in the special case of a linear model for some transform of the location parameter. The Butler approximate predictive likelihood (Butler, 1986, Rejoinder) is then used to define likelihood prediction envelopes. The width of these intervals is shown to be slightly wider than the Fisher (1959, pp. 128-33) and Lejeune and Faulkenberry (1982) predictive likelihood-based envelopes which assume that the parameters have fixed known values (equal to their maximum likelihood estimates). The method is illustrated on a small count data set showing overdispersion. [less ▲]

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See detailInduction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells.
Polette, M.; Gilles, Christine ULg; Marchand, V. et al

in Clinical & Experimental Metastasis (1997), 15(2), 157-63

Membrane-type matrix metalloproteinase 1 (MT1-MMP) has been recently described as an activator of proMMP-2 (MMP-2) which is involved in tumor invasion. We have shown by in situ hybridization that MT1-MMP ... [more ▼]

Membrane-type matrix metalloproteinase 1 (MT1-MMP) has been recently described as an activator of proMMP-2 (MMP-2) which is involved in tumor invasion. We have shown by in situ hybridization that MT1-MMP is produced by stromal cells in close contact to preinvasive and invasive tumor cells of breast carcinomas. Of particular interest was the observation that some fibroblasts express this enzyme in focal areas in preinvasive lesions, suggesting that particular tumor cells may stimulate fibroblasts to produce MT1-MMP. We have therefore compared the ability of two different breast cancer cell lines, one non-invasive (MCF7) and one invasive (MDA-MB-231) to stimulate MT1-MMP production in human fibroblasts with consequent proMMP-2-activation. The MDA-MB-231 conditioned medium induced MT1-MMP mRNAs in human fibroblasts and a parallel activation of proMMP-2 whereas MCF7 conditioned medium did not have any effect. These results suggest the existence of soluble factor(s) secreted by invasive or some preinvasive breast tumor cells which stimulate fibroblasts to produce and activate MMPs, and emphasize the cooperation between cancer and stromal cells in tumor invasion. [less ▲]

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See detailAnaemia of lung cancer is due to impaired erythroid marrow response to erythropoietin stimulation as well as relative inadequacy of erythropoietin production.
Dowlati, A.; R'Zik, Samir ULg; Fillet, Georges ULg et al

in British Journal of Haematology (1997), 97(2), 297-9

Many studies have been done in order to elucidate the pathogenesis of the anaemia of chronic disorders accompanying cancer, with conflicting results. This is probably due to the heterogeneity of the ... [more ▼]

Many studies have been done in order to elucidate the pathogenesis of the anaemia of chronic disorders accompanying cancer, with conflicting results. This is probably due to the heterogeneity of the patient population selected for these studies (many patients treated by chemotherapy). To avoid this pitfall, in this study a very homogenous group of chemotherapy and radiotherapy-naive patients with lung cancer were selected. Serum erythropoietin and soluble transferrin receptor measurements suggested that the anaemia of non-treated lung cancer is mainly due to an impaired erythroid marrow response to erythropoietin stimulation. However, a relative inadequacy of erythropoietin production may also contribute. [less ▲]

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See detailEngraissement du taurillon Blanc-Bleu belge
Minet, Vincent; Van Eenaeme, Christian ULg; Raskin, Pascale et al

in Agricontact (1997), 291

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See detailPregnancies after vitrification of human day 5 embryos
Vanderzwalmen, Pierre ULg; Delval, Alain; Chatziparasidou, A. et al

in Human Reproduction (1997), 12(suppl), 98

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See detailA two-dimensional Navier-Stokes inverse solver for compressor and turbine blade design
Demeulenaere, A.; Léonard, Olivier ULg; Van den Braembussche, René

in Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy (1997), 211(4), 299-307

A two-dimensional viscous inverse method for the design of compressor and turbine blades is presented. It iteratively modifies an initial geometry until a prescribed pressure distribution is reached on ... [more ▼]

A two-dimensional viscous inverse method for the design of compressor and turbine blades is presented. It iteratively modifies an initial geometry until a prescribed pressure distribution is reached on the blade surface. The method solves the time-dependent Navier-Stokes equations in a numerical domain of which some boundaries (the blade walls) move during the transient part of the computation. The geometry modification algorithm is based on the transpiration principle: a normal velocity distribution is computed from the difference between the actual and prescribed pressure distributions, and is used to modify the blade shape. A time iteration is then performed on this new blade shape, taking into account the grid movement during the time stepping. A two-dimensional upwind finite-volume Navier-Stokes solver has been developed. The multiblock strategy allows for a selective concentration of the discretization points in the zones of higher gradients. Applications to turbine and compressor blade design illustrate the accuracy of the flow computation, the capabilities and efficiency of the inverse method. [less ▲]

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See detailAcetaldehyde-induced changes in the monoamine and amino acid extracellular microdialysate content of the nucleus accumbens
Ward, Roberta J.; Colantuoni, Carlo; Dahchour, Abdelkhader et al

in Neuropharmacology (1997), 36(2), 225-232

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by ... [more ▼]

The effect of an acute intraperitoneal (i.p.) injection of acetaldehyde, 20 mglkg or 100mg/kg, on the microdialysate content of both amino acids and monoamine was studied in the nucleus accumbens (NA) by a microdialysis technique. Acetaldehyde (ACH) which was detectable at levels of 50-130 µmol/g brain tissue 10 min after injection, evoked a significantd ecrease in the extracellular microdialysis dopamine content, which was sustained for the period of the study, i.e. 120 min. Homovanillicacid, HVA, decreased significantly when the lower dose of ACH was administered while dihydrophenylaceticacid, DOPAC, showed no significant change with either dose of ACH during the period of the study. Serotonin levels decreased significantly after both doses of acetaldehyde, with significant increases of its major metabolite, hydroxyindolacetic acid, 5-HIAA, with the higher acetaldehyde dose. Taurine increased significantly, only during the first twenty minutes, after both doses of acetaldehyde, although neither of the excitatory amino acids assayed, glutamate and aspartate, nor the inhibitoryamino acid, GABA, showed any significant changes. Acetaldehyde clearly evokes significant perturbation in the monoamine content of the NA, such changes being the converse to those reported for monoamine after ethanol administration, which might indicate a negative reinforcement effect. [less ▲]

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See detailThe state of stress near the Mendocino triple Junction from inversion of earthquake focal mechanism
Schwartz, S. Y.; Hubert, Aurelia ULg

in Geophysical Research Letters (1997), 23

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See detailStepwise introduction of pi-electron cross-conjugaison: a possible access to [5] radialenes ?
Geneste, Florence; Moradpour, Alec; Dive, Georges ULg

in Journal of Organic Chemistry (1997), 62(16), 5339-5343

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See detailIn search of the Latin American Faulkner
Vanden Berghe, Kristine ULg

in Target : International Journal of Translation Studies (1997), 9(2), 399-400

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See detailDopamine 'D2-like' receptor agonists in combination with cocaine: absence of interactive effects on locomotor activity.
Tirelli, Ezio ULg; Reggers, Jean ULg; Terry, P.

in Behavioural Pharmacology (1997), 8(2-3), 147-59

This study examined interactions between cocaine and drugs that act as direct agonists at subtypes of "D2-like" dopamine receptors. The drugs 7-OH-DPAT, quinpirole and RU24213 were studied alone and in ... [more ▼]

This study examined interactions between cocaine and drugs that act as direct agonists at subtypes of "D2-like" dopamine receptors. The drugs 7-OH-DPAT, quinpirole and RU24213 were studied alone and in combination with cocaine for their effects on locomotor activity in non-habituated mice. Locomotor activity was measured by photobeam crossings over 140 min. At the doses given (7-OH-DPAT: 0.006-6.4 mg/kg; quinpirole: 0.001-1 mg/kg; RU24213: 0.008-8 mg/kg) all three direct agonists dose-dependently reduced locomotor activity throughout the test, whereas cocaine (0.6-20 mg/kg) produced dose-related hyperactivity. Next, for each direct agonist, a series of doses was selected (up to threshold behaviourally-active doses) as pretreatments to a sub-maximally stimulant dose of cocaine (15 mg/kg). 7-OH-DPAT and quinpirole did not modulate the effects of cocaine; RU24213 produced, at best, a very modest attenuation of the effects of cocaine. Finally, a series of cocaine doses (below stimulant threshold) was given before a single dose of each direct agonist (the lowest dose to reduce activity significantly). Cocaine did not reliably alter the hypoactivity produced by any of the D2-like agonists. By demonstrating negligible interactions between cocaine and D2-like agonists, the results fail to demonstrate any necessary involvement of D2-like receptors in one of the behavioural effects of cocaine. [less ▲]

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See detailLes strychnos africains et leurs alcaloïdes
Delaude, Clément ULg; Delaude, Lionel ULg

in Bulletin de la Société Royale des Sciences de Liège (1997), 66(4), 183-286

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the ... [more ▼]

In the Greek Antiquity, the term strychnos was first coined to describe various toxic Solanacae. Nowadays, the genus Strychnos created by Linnaeus in 1753 is the numerically most important genus from the Loganiaceae family and comprises 196 species growing in the warm regions of Asia (58 species), America (64) and Africa (75). Species on the three continents are almost totally segregated. Only Strychnos potatorum is common to Asia and Africa. The toxicity of Strychnos was empirically well-known from time immemorial. Inhabitants of South-Eastern Asia and India had an ancestral knowledge of Strychnos nux vomica, whose deadly poisonous seeds were later imported and marketed in Europe to kill rodents and small predators. Concentrated extracts from Amazonian Strychnos, known as curares, are also remarkable hunting poisons, used by South American Indians. Accordingly, modern scientific investigations of Strychnos and their alkaloids started with Asian or American species used as traditionnal poisons. Strychnine was the first alkaloid found in Strychnos. It was isolated from Asian S. nux vomica in 1818, but its structure was fully elucidated only in the 1950s. Meanwhile, various curarizing alkaloids from American Strychnos were identified. Based on these early results, Strychnos alkaloids were initially classified according to their geographical origin. Asian Strychnos were assumed to contain strychnine and related compounds, whereas curarizing ammonium salts were associated with American Strychnos. African species were assimilated to their Asian counterparts and deemed of less interest. During the last three decades, however, systematic screening of African Strychnos has revealed the presence of numerous, varied alkaloids in these plants and demonstrated that the correlation between geographical distribution and alkaloid content was erroneous. Presently, 47 African species have been investigated and their alkaloids analyzed, significantly more than Asian and American materials (about 10 and 20 species, respectively). In this review, we present the alkaloids isolated so far from African Strychnos. 309 structures are listed and sorted according to their molecular weight, the most useful index key in modern research based on mass spectrometry. [less ▲]

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See detailBenchmarks for finite element modelling of bolted steel connections
Bursi, O.; Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (1997), 43(Nos 1-3),

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See detailCell-line specific radiosensitizing effect of zalcitabine (DDC)
Coucke, Philippe ULg; Li, Ye-Xiong; Copaceanu, Marie-Laure et al

in Acta Oncologica (1997)

The potential of zalcitabine (ddC) to act as an ionizing radiation response modifier was tested on exponentially growing human cancer cells in vitro. Two human cell lines, WiDr (colon) and MCF-7 (breast ... [more ▼]

The potential of zalcitabine (ddC) to act as an ionizing radiation response modifier was tested on exponentially growing human cancer cells in vitro. Two human cell lines, WiDr (colon) and MCF-7 (breast) were exposed to ddC at 10 p M concentration for various lengths of tide (18, 24, 48 and 72 h). On the WiDr cell line the dual effect of concentration and duration of exposure prior to irradiation was investigated. Experimental endpoints were clonogenicity and viability, as measured by colony formation assay (CFA) and MTT assay respectively. The impact on cell-cycle distribution prior to irradiation was assessed by flow cytometry using a double labeling technique (propidium iodide and bromodeoxyuridine pulse label). A significant reduction in surviving fraction and viability was observed for WiDr-cells irradiated after pre-exposure to 10 pM for 18, 48 and 72 h as compared to corresponding irradiated controls. At lower concentrations (1 and 5 pM), the radiosensitizing effect was only significant after a 72-h exposure (assessed by CFA). For MCF-7, ddC induced a significant modification of the dose response only with 24 and 48 h preincubation. However, the overall effect was less pronounced as compared to WiDr. Cell-cycle analysis showed accumulation in S-phase, 48 and 72 h after treatment with 10 pM ddC in the WiDr cells, with a progressive shift to late S-phase as shown by the biparametric analysis. The degree of radiosensitization is cell-line dependent with the most important sensitization observed on the most <<radioresistant cell line>>, ix., the cell line with the lowest alpha value and highest SF 2 (WiDr). For WiDr, radiosensitization by ddC depends on the duration of exposure and the concentration of the drug. Received 29 February 1996 Accepted 10 December 1996 [less ▲]

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See detailSpecies assemblages and indicator species: The need for a flexible asymmetrical approach
Dufrêne, Marc ULg; Legendre, P.

in Ecological Monographs (1997), 67(3), 345-366

This paper presents a new and simple method to find indicator species and species assemblages characterizing groups of sites. The novelty of our approach lies in the way we combine a species relative ... [more ▼]

This paper presents a new and simple method to find indicator species and species assemblages characterizing groups of sites. The novelty of our approach lies in the way we combine a species relative abundance with its relative frequency of occurrence in the various groups of sites. This index is maximum when all individuals of a species are found in a single group of sites and when the species occurs in all sites of that group; it is a symmetric indicator. The statistical significance of the species indicator values is evaluated using a randomization procedure. Contrary to TWINSPAN, our indicator index for a given species is independent of the other species relative abundances, and there is no need to use pseudospecies. The new method identifies indicator species for typologies of species releves obtained by any hierarchical or nonhierarchical classification procedure; its use is independent of the classification method. Because indicator species give ecological meaning to groups of sites, this method provides criteria to compare typologies, to identify where to stop dividing clusters into subsets, and to point out the main levels in a hierarchical classification of sites. Species can be grouped on the basis of their indicator values for each clustering level, the heterogeneous nature of species assemblages observed in any one site being well preserved. Such assemblages are usually a mixture of eurytopic (higher level) and stenotopic species (characteristic of lower level clusters). The species assemblage approach demonstrates the importance of the 'sampled patch size,' i.e., the diversity of sampled ecological combinations, when we compare the frequencies of core and Satellite species. A new way to present species-site tables, accounting for the hierarchical relationships among species, is proposed. A large data set of carabid beetle distributions in open habitats of Belgium is used as a case study to illustrate the new method. [less ▲]

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See detailOn endostyle ultrastructure in two new species of doliolid-like tunicates
Compère, Philippe ULg; Godeaux, Jean

in Marine Biology (1997), 128

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See detailNutrient utilisation and particulate organic matter changes during summer in the upper mixed layer (Ross Sea, Antarctica).
Catalano, Giulio; Povero, Paolo; Fabiano, Mauro et al

in Deep-Sea Research Part I, Oceanographic Research Papers (1997), 44(1), 97-112

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 ... [more ▼]

The relationships among vertical stability, estimated nutrient utilisation and particulate organic matter in the Ross Sea are analysed from data collected during two cruises in the summers of 1987 - 88 and 1989 - 90. In the upper mixed layer (UML), identified through the vertical stability E(Z(UML)), nutrient consumption is calculated as the difference between the « diluted » nutrient value and the mean calculated from the integrated value in the UML. The nutrient utilisation ratio and E(Z(UML)) are linearly related for E(Z(UML)) < 25, whereas for values > 25, the distribution pattern is more scattered and independent of E(Z(UML)). For E(Z(UML)) > 25, utilisation values were > 4, 0.4 and 10 mmol m-3 for nitrate, phosphate and silicate, respectively. Significant relationships between nutrient depletion and both particulate organic carbon (POC) and particulate protein / particulate carbohydrate ratios (PPRT/PCHO) are found. The analysis of particulate matter distribution vs nutrient utilisation shows that the stations could be divided into two groups having different characteristics. The first group includes coastal stations, where high nutrient utilisation, POC and PPRT / PCHO are typical of areas with high production. In the second group (pelagic stations), nutrient utilisation, POC and PPRT / PCHO are lower. The vertical stability can be used to discriminate among the factors that influence primary production. [less ▲]

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See detailProductivity and Convergence in OECD Service Industries
Gouyette, Claudine; Perelman, Sergio ULg

in Structural Change and Economic Dynamics (1997), 8

The objective of this paper is threefold. First, to estimate the productivity performances realized in service and manufacturing industries by 13 OECD countries over the period 1970-1987. Secondly, to ... [more ▼]

The objective of this paper is threefold. First, to estimate the productivity performances realized in service and manufacturing industries by 13 OECD countries over the period 1970-1987. Secondly, to compare the productivity indicators computed under the alternative frontier analysis and Divisia index approaches. Thirdly, to test the convergence phenomenon in both industries, focusing on the catching-up process and on the interaction between productivity changes and capital intensity variations. The main results show that, contrary to the manufacturing sector and in spite of very low growth rates, productivity levels converge in services. Moreover, new investments in capital appear to exert an unexpected depressive effect on total factor productivity growth in service activities, while having a positive influence in manufacturing industries. [less ▲]

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See detailObserved trends in total vertical column abundances of atmospheric gases from IR solar spectra recorded at the Jungfraujoch
Mahieu, Emmanuel ULg; Zander, Rodolphe ULg; Delbouille, Luc et al

in Journal of Atmospheric Chemistry (1997), 28(1-3), 227-243

Since 1984, about 15 000 high quality infrared solar spectra have been recorded with state-of-the-art grating and Fourier transform spectrometers at the International Scientific Station of the ... [more ▼]

Since 1984, about 15 000 high quality infrared solar spectra have been recorded with state-of-the-art grating and Fourier transform spectrometers at the International Scientific Station of the Jungfraujoch, Switzerland. Nonlinear least squares spectral curve fitting of selected microwindows containing isolated and well characterized lines of 20 telluric gases have allowed to retrieve their total vertical column abundances above the station, leading to observational data bases essential to derive long- and short-term changes experienced by these species during the last 12 years. In this paper, we focus on atmospheric gases of particular interest within the context of the EUROTRACTOR (Tropospheric Ozone Research) project; secular evolution as well as seasonal cycles of the minor constituents CH4, CO and of the trace gases C2H6, OCS, C2H2, HCN and H2CO are reported and discussed. The long-lived N2O is included as a tracer of the dynamic activity of the atmosphere. [less ▲]

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See detailPlasma leptin levels, insulin secretion, clearance and action on glucose metabolism in anorexia nervosa.
Letiexhe, Michel ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Eating and Weight Disorders [=EWD] (1997), 2(2), 79-86

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose ... [more ▼]

From a metabolic point of view, anorexia nervosa may be viewed as a mirror image of obesity. We compared insulin secretion, clearance and action on glucose metabolism during an intravenous glucose tolerance test in nine women with anorexia nervosa and in nine age-matched normal-weight controls. Insulin secretion (ISR) was derived by deconvolution of plasma C-peptide levels, insulin clearance (MCR(I)) was obtained by dividing the area under the curve (AUC(0-180 min)) of ISR by the corresponding AUC of plasma insulin levels, insulin sensitivity (S(I)) and glucose effectiveness index (S(G)) were calculated by Bergman's minimal model. The anorectic women had markedly lower BMI values (13.7+/-0.6 vs 23.2+/-0.8 kg/m2, p<0.0001) and serum basal leptin levels (2.8+/-0.6 vs 8.9+/-1.8 ng/mL, p=0.005) than control women. The anorectic women exhibited clear-cut lower fasting and post-glucose plasma insulin levels but similar corresponding plasma C-peptide concentrations when compared to controls. Consequently, ISR was similar in both groups while MCR(I) was significantly increased in anorexia nervosa (MCR(I): 3320+/-881 vs 822+/-79 mL x min(-1) x m(-2), p<0.02). The index S(I) tended to be higher in anorectic women than in normal-weight subjects, but without reaching the level of statistical significance because of a high between-subject variability (20.2+/-5.7 vs 12.5+/-2.2 10(-5) x min(-1)/pmol x L(-1), NS). The index S(G) was similar in both groups (0.022+/-0.004 vs 0.018+/-0.002 min(-1), NS). In conclusion, low plasma insulin levels observed in women with anorexia nervosa result from high MCR(I) rather than from depressed insulin secretion. Insulin sensitivity is not systematically increased and glucose effectiveness is unchanged in anorectic women when compared to normal-weight controls. [less ▲]

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See detail"Saint Lambert au banquet de Jupille". Auguste Chauvin (1810-1884) et la peinture d'histoire
George, Philippe ULg

in Bulletin de la Société Royale Le Vieux-Liège (1997), T. XIII, n° 276

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See detailDe l’acyclovir au valacyclovir: la biodisponibilité en plus de l’efficacité et de la tolérance
Rentier, Bernard ULg

in Virologics (1997), (Septembre), 10-11

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See detailPhenylarsine oxide inhibits ex vivo HIV-1 expression
Edeas, M.; Arbault, S.; Legrand-Poels, Sylvie ULg et al

in Biomedicine & Pharmacotherapy (1997)

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See detailCompte rendu du Cahier de Linguistique française, n°14 : Lexique et pragmatique
Defays, Jean-Marc ULg

in Français Moderne (Le) (1997), (2), 239-244

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See detailThe effects of ammonium sulphate deposition and root sinks on soil solution chemistry in coniferous forest soils
Carnol, Monique ULg; Ineson, Phil; Anderson, J. M. et al

in Biogeochemistry (1997), 38

The effects of enhanced (NH4)(2)SO4 deposition on soil solution cation and anion concentrations and annual ionic fluxes were followed using a standardised experimental protocol in six European coniferous ... [more ▼]

The effects of enhanced (NH4)(2)SO4 deposition on soil solution cation and anion concentrations and annual ionic fluxes were followed using a standardised experimental protocol in six European coniferous forests with contrasting soil types, pollution inputs and climate. Native soil cores containing a ceramic suction cup were installed in the field, roofed and watered every two weeks with local throughfall or local throughfall with added (NH4)(2)SO4 at 75 kg NH4+-N ha(-1) a(-1). Living root systems were established in half of the lysimeters. Untreated throughfall NH4+-N deposition at the sites ranged from 3.7 to 29 kg ha(-1) a(-1). Soil leachates were collected at two weekly intervals over 12 months and analysed for volume, and concentrations of major anions and cations. Increases in soil solution NO3- concentrations in response to N additions were observed after 4-9 months at three sites, whilst one sandy soil with high C:N ratio failed to nitrify under any of the treatments. Changes in NO3- concentrations in soil solution controlled soil solution cation concentrations in the five nitrifying soils, with Al3+ being the dominant cation in the more acid soils with low base saturation. The acidification responses of the soils to the (NH4)(2)SO4 additions were primarily related to the ability of the soils to nitrify the added NH4+. pH and soil texture seemed important in controlling NH4+ leaching in response to the treatments, with two less acidic, clay/clay loam sites showing almost total retention of added NH4+, whilst nearly 75% of the added N was leached as NH4+ at the acid sandy soils. The presence of living roots significantly reduced soil solution NO3- and associated cation concentrations at two of the six sites. The very different responses of the six soils to increased (NH4)(2)SO4 deposition emphasise that the establishment of N critical loads for forest soils need to allow for differences in N storage. capacity and nitrification potential. [less ▲]

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See detailImproved emulsifying and foaming of whey proteins after enzymic fat hydrolysis
Blecker, Christophe ULg; Paquot, Michel ULg; Lamberti, I. et al

in Journal of Food Science (1997), 62(1), 48-

In an effort to improve emulsifying and foaming of sweet whey and whey protein concentrate, we studied the hydrolysis of the residual fat in these preparations with a sn 1,3 specific lipase. This ... [more ▼]

In an effort to improve emulsifying and foaming of sweet whey and whey protein concentrate, we studied the hydrolysis of the residual fat in these preparations with a sn 1,3 specific lipase. This enzymatic lipolysis would convert almost all triglycerides into mono- and diglycerides which have strong surface-active properties. Therefore, the emulsifying and foaming capacities of such modified whey products should be increased in comparison with native products, as shown by results presented at both neutral pH and those similar to a salad dressing emulsion. It was also demonstrated that emulsions and foams formed with lipase-treated whey preparations were more shelf-stable. [less ▲]

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See detailSynthesis and characterization of monodisperse spherical zirconia particles
Van Cantfort, Olivier; Michaux, Bernard; Pirard, René ULg et al

in Journal of Sol-Gel Science and Technology (1997), 8

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See detailGEQUAC, an Excess Gibbs Energy Model for Simulta¬neous Description of Associat-ing and Non-Associating Liquid Mixtures
Egner, K; Gaube, J; Pfennig, Andreas ULg

in Berichte der Bunsengesellschaft für physikalische Chemie (1997), 101(2), 209-218

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See detailDevelopment of a monoclonal antibody to urinary degradation products from the C-terminal telopeptide 1 chain of type I collagen. Application in an enzyme immunoassay and comparison to Crosslaps TM Elisa
Fledelius, C; Kolding, I; Qvist, P et al

in Scandinavian Journal of Clinical & Laboratory Investigation (1997), 57

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See detailDevelopment of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression : Synthesis and in vitro evaluation of 9-{3-[18F] Fluoro-1-hydroxy-2-propoxymethyl guanine
Monclus, Michel; Luxen, André ULg; Cool, Vincent et al

in Bioorganic and Medicinal Chemistry Letters (1997), 7(14), 1879-1882

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission ... [more ▼]

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission tomography (PET). [less ▲]

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See detailRuptured Aneurysm of the Profunda Femoral Artery Associated with Polyaneurysmal Disease
Defraigne, Jean-Olivier ULg; Vasquez, C.; Limet, Raymond ULg

in Acta Chirurgica Belgica (1997), 97(2), 93-6

A 73-year-old man was admitted for rupture of an atherosclerotic aneurysm of the profunda femoris artery associated to popliteal and bilateral axillary arteries aneurysms. The aneurysm of the profunda ... [more ▼]

A 73-year-old man was admitted for rupture of an atherosclerotic aneurysm of the profunda femoris artery associated to popliteal and bilateral axillary arteries aneurysms. The aneurysm of the profunda femoris artery was developed between the branches of the crural nerves. Considering the patency of the superficial femoral artery and of the leg arterie, and to avoid injury to the crural nerve, no reconstruction of the profunda femoris was attempted. The aneurysm was ligated proximally and buttress sutures were placed on the site of rupture to achieve thrombosis of the aneurysms. Most of the published cases of aneurysm of the profunda femoris artery are false aneurysms developed after various trauma. Atherosclerotic aneurysm of the profunda femoris artery is a rare lesion and rupture is exceptional. [less ▲]

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See detailDetermination rapide par immunodosage de l'hemoglobine glyquee sur sang capillaire comparee a une methode d'affinite pour le boronate et capture d'ions sur sang veineux.
Bozet, Marie-Claire ULg; Gerard, Pascale ULg; Scheen, André ULg et al

in Annales de Biologie Clinique (1997), 55(2), 139-44

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary ... [more ▼]

Measurement of glycosylated haemoglobin has become an essential tool in the management of diabetic patients. A recently developed device allows the rapid immuno-assay of HbA1c in 1 microliter capillary blood obtained by a finger prick. In 100 ambulatory diabetic patients, we compared the results obtained with this method to those obtained in venous blood using a standard affinity chromatography laboratory method. Although both methods correlated (r = 0.88, p < 0.001), the mean +/- SD levels respectively obtained differed slightly (7.6 +/- 1.5 vs 79 +/- 1.4% p < 0.001). The 95% confidence interval of the difference was [-0.41. -0.14]. Considering a cut-off HbA1c value of 8%, as indicative of the need for treatment adjustment, 33 patients with the capillary blood immuno-assay method and 42 with the venous-blood affinity chromatography method were above that limit (Mc Nemar test, p < 0.05). In conclusion, the rapid assay of HbA1c in capillary blood can be useful for the management of some diabetic patients but the results are not readily exchangeable with those obtained from other standardized laboratory methods. Consequently, specific ranges and clinical decision limits must be determined. [less ▲]

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See detailQuelques reflexions sur les contraintes alimentations dans la production caprine en milieu tropical
Mayombo, Asangule Pierre; Hornick, Jean-Luc ULg

in Le N'Dama (1997)

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See detailEffect of beef type, body weight and dietary protein content on voluntary feed intake, digestibility, blood and urine metabolites and nitrogen retention
Fiems, Leo; Cottyn, B. G.; Boucqué, Charly et al

in Journal of Animal Physiology & Animal Nutrition (1997), 77

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See detailMétastases ganglionnaires, hépatiques et osseuses d'un chemodectome carotidien. A propos d'un cas
DEFRAIGNE, Jean ULg; Limet, Raymond ULg

in Journal de Chirurgie (1997), 134(7-8), 336-9

A case of malignant carotid body tumor with nodal, hepatic and bone metastases is reported. Carotid body chemodectomas are slow-growing tumors which invade local structures. These tumors are usually ... [more ▼]

A case of malignant carotid body tumor with nodal, hepatic and bone metastases is reported. Carotid body chemodectomas are slow-growing tumors which invade local structures. These tumors are usually benign but can occasionally produce local and distant metastases. Development of metastatic localizations is the only formal proof of malignancy as histology cannot distinguish between benign and malignant chemodectomas. Bilateral carotid arteriography gives the diagnosis. Surgery is the basis of treatment and should be performed early in the course to limit operative complications. Radiotherapy can be given as adjuvant treatment. [less ▲]

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See detailLes comportements des enseignants dans la perspective d'un traitement différencié des élèves
Piéron, Maurice; Ledent, Maryse; Pirottin, Véronique et al

in Revue de l'Education Physique (1997), 4

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe ... [more ▼]

La pédagogie basée sur la théorie des "rythmes d'apprentissage" accorde une place privilégiée à l'individualisation et contredit le principe d'une programmation uniforme, valable pour tous. Toute classe est hétérogène, chaque enfant étant singulier, différent dans ses valeurs, ses attitudes, ses potentialités et ses compétences. Chacun apprend à un rythme différent, plus rapidement que la moyenne dans des domaines, moins rapidement dans d'autres. ... [less ▲]

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See detailHypochlorous acid activates NF-kappaB transcription factor in T lymphocytes
Schoonbroodt, Sonia; Legrand-Poels, Sylvie ULg; Best-Belpomme, Martin et al

in Biochemical Journal (1997)

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See detailOptimization of murine CD8+ cytotoxic T-lymphocyte responses to pseudorabies virus
Depierreux, C.; Graff, I.; Lancelot, V. et al

in Journal of Immunological Methods (1997), 203

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See detailElectron tomography of metaphase nucleolar organizer regions: evidence for a twisted-loop organization.
Heliot, L.; Kaplan, H.; Lucas, L. et al

in Molecular Biology of the Cell (1997), 8(11), 2199-216

Metaphase nucleolar organizer regions (NORs), one of four types of chromosome bands, are located on human acrocentric chromosomes. They contain r-chromatin, i.e., ribosomal genes complexed with proteins ... [more ▼]

Metaphase nucleolar organizer regions (NORs), one of four types of chromosome bands, are located on human acrocentric chromosomes. They contain r-chromatin, i.e., ribosomal genes complexed with proteins such as upstream binding factor and RNA polymerase I, which are argyrophilic NOR proteins. Immunocytochemical and cytochemical labelings of these proteins were used to reveal r-chromatin in situ and to investigate its spatial organization within NORs by confocal microscopy and by electron tomography. For each labeling, confocal microscopy revealed small and large double-spotted NORs and crescent-shaped NORs. Their internal three-dimensional (3D) organization was studied by using electron tomography on specifically silver-stained NORs. The 3D reconstructions allow us to conclude that the argyrophilic NOR proteins are grouped as a fiber of 60-80 nm in diameter that constitutes either one part of a turn or two or three turns of a helix within small and large double-spotted NORs, respectively. Within crescent-shaped NORs, virtual slices reveal that the fiber constitutes several longitudinally twisted loops, grouped as two helical 250- to 300-nm coils, each centered on a nonargyrophilic axis of condensed chromatin. We propose a model of the 3D organization of r-chromatin within elongated NORs, in which loops are twisted and bent to constitute one basic chromatid coil. [less ▲]

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See detailNucleon nucleon interaction in a chiral constituent quark model
Stancu, Floarea ULg; Pepin, S.; Glozman, L Ya

in Physical Review. C : Nuclear Physics (1997), C56

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between ... [more ▼]

We study the short-range nucleon-nucleon interaction in a chiral constituent quark model by diagonalizing a Hamiltonian comprising a linear confinement and a Goldstone boson exchange interaction between quarks. The six-quark harmonic oscillator basis contains up to two excitation quanta. We show that the highly dominant configuration is $\mid s^4p^2[42]_O [51]_{FS}>$ due to its specific flavour-spin symmetry. Using the Born-Oppenheimer approximation we find a strong effective repulsion at zero separation between nucleons in both $^3S_1$ and $^1S_0$ channels. The symmetry structure of the highly dominant configuration implies the existence of a node in the S-wave relative motion wave function at short distances. The amplitude of the oscillation of the wave function at short range will be however strongly suppressed. We discuss the mechanism leading to the effective short-range repulsion within the chiral constituent quark model as compared to that related with the one-gluon exchange interaction. [less ▲]

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See detailcDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components.
Colige, Alain ULg; Li, S. W.; Sieron, A. L. et al

in Proceedings of the National Academy of Sciences of the United States of America (1997), 94(6), 2374-9

Procollagen N-proteinase (EC 3.4.24.14) cleaves the amino-propeptides in the processing of type I and type II procollagens to collagens. Deficiencies of the enzyme cause dermatosparaxis in cattle and ... [more ▼]

Procollagen N-proteinase (EC 3.4.24.14) cleaves the amino-propeptides in the processing of type I and type II procollagens to collagens. Deficiencies of the enzyme cause dermatosparaxis in cattle and sheep, and they cause type VIIC Ehlers-Danlos syndrome in humans, heritable disorders characterized by accumulation of pNcollagen and severe skin fragility. Amino acid sequences for the N-proteinase were used to obtain cDNAs from bovine skin. Three overlapping cDNAs had an ORF coding for a protein of 1205 residues. Mammalian cells stably transfected with a complete cDNA secreted an active recombinant enzyme that specifically cleaved type I procollagen. The protein contained zinc-binding sequences of the clan MB of metallopeptidases that includes procollagen C-proteinase/BMP-1. The protein also contained four repeats that are homologous to domains found in thrombospondins and in properdin and that can participate in complex intermolecular interactions such as activation of latent forms of transforming growth factor beta or the binding to sulfatides. Therefore, the enzyme may play a role in development that is independent of its role in collagen biosynthesis. This hypothesis was supported by the observation that in some tissues the levels of mRNA for the enzyme are disproportionately high relative to the apparent rate of collagen biosynthesis. [less ▲]

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See detailMesures d'incitation en faveur de la conservation de la diversite genetique en matiere agricole. 2. Analyse des mesures agri-environnementales belges.
Lepoivre, Philippe ULg; Baltus, Carine

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(3), 187-195

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See detailAntibodies against vaccinia virus do not neutralize extracellular enveloped virus but prevent virus release from infected cells and comet formation
Vanderplasschen, Alain ULg; Hollinshead, M.; Smith, G. L.

in Journal of General Virology (The) (1997), 78(Pt 8), 2041-2048

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See detailLes téléports en Europe: état actuel et perspectives offertes par les "call centers"
Jacob, Damien ULg

in Revue Géographique de l'Est (1997), 37(4), 273-284

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts ... [more ▼]

De manière à répondre à l'accroissement de l'offre et de la demande en télécommunications d'entreprises constaté ces dernières années, trois grandes catégories de téléports proposant des services à coûts partagés et les téléports " hub ", concentrant les flux de communication en un point central. Les téléports ciblent des entreprises exigeant un haut niveau de services en télécommunications, par exemple les centres d'appels téléphoniques. Cette activité, en pleine expansion en Europe, recherche une main-d'œuvre multilingue pouvant assurer par téléphone des services d'information, de conseil, de vente et d'après-vente. Les téléports peuvent donc devenir des outils attractifs pour attirer ce créneau particulièrement porteur en création d'emplois, même si ces derniers sont pour une bonne part une transformation d'anciennes tâches et paraissent potentiellement faciles à délocaliser vers des pays à faible coût du travail. [less ▲]

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See detailPd/SiO2-cogelled aerogel catalysts and impregnated aerogel and xerogel catalysts: Synthesis and characterization
Heinrichs, Benoît ULg; Noville, Francis ULg; Pirard, Jean-Paul ULg

in Journal of Catalysis (1997), 170(2), 366-376

Pd/SiO2 aerogel catalysts have been synthesized by cogelation of tetraethoxysilane with complex Pd2+[NH2-CH2-CH2-NH-(CH2)(3)-Si(OCH3)(3)](2) containing a hydrolysable silyl group. Pd catalysts have also ... [more ▼]

Pd/SiO2 aerogel catalysts have been synthesized by cogelation of tetraethoxysilane with complex Pd2+[NH2-CH2-CH2-NH-(CH2)(3)-Si(OCH3)(3)](2) containing a hydrolysable silyl group. Pd catalysts have also been prepared by impregnation of silica aerogels and xerogels with solutions of this complex or Pd2+(NH3)(4) followed by drying under hypercritical conditions or under vacuum. It appears that, in cogelled samples, the Pd2+ complex acts as a nucleation agent in the formation of silica particles. The resulting catalysts are then composed of completely accessible palladium crystallites with a diameter of about 2.3 nm located inside silica particles with a monodisperse microporous distribution centered on a hydraulic radius of 0.43 nm. The continuous meso- and macropore distribution is located in voids between particles and between aggregates constituted of those particles. In impregnated samples, it appears that Pd particles are located outside SiO2 particles. The relation between the texture of cogelled and impregnated catalysts and their behavior toward sintering has been studied in detail. In cogelled samples, it has been shown that Pd crystallites cannot migrate because they are trapped in the pores of SiO2 particles. These catalysts are sinterproof during hypercritical drying, When Pd crystallites are not trapped inside SiO2 particles, hypercritical drying leads to an extensive sintering of metal particles. During calcination of impregnated catalysts dried under vacuum, sintering occurs to a various extent depending on the support texture. The Pd crystallites size decreases when the pore size distribution is shifted toward the small sizes. (C) 1997 Academic Press. [less ▲]

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See detailTrois ivoires médiévaux au Musée de l’Oeuvre Notre-Dame à Strasbourg
Van den Bossche, Benoît ULg

in Cahiers Alsaciens d’Archéologie, d’Art et d’Histoire (1997), XL

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See detailCiclosporine et maladies systémiques
Andre, Béatrice ULg; Ribbens, Clio ULg; Kaye, O. et al

in Médecine et Hygiène (1997), 55

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See detailLe niveau de lecture à l'entrée du secondaire en Communauté française de Belgique: Des compétences fragiles et si diverses…
Lafontaine, Dominique ULg

in Enjeux : Revue de Formation Continuée et de Didactique du Français (1997), 41-42(129), 161

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See detailSquare cells in gravitational and capillary thermoconvection
Regnier, Vincent; Dauby, Pierre ULg; Parmentier, P. et al

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1997), 55(6), 6860-6865

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See detailMitochondrial Asparaginyl-Trna Synthetase Is Encoded By The Yeast Nuclear Gene Ycr24c
Landrieu, I.; Vandenbol, Micheline ULg; Hartlein, M. et al

in European Journal of Biochemistry (1997), 243(1-2),

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See detailThe Effects of Hypertonic Saline in Healthy and Diseased Animals
Cambier, Carole ULg; Ratz, V.; Rollin, Frédéric ULg et al

in Veterinary Research Communications (1997), 21(5), 303-316

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the ... [more ▼]

In this review, the pharmacological effects of administering hypertonic solutions to both healthy animals and during experimentally induced diseases are considered with a view to understanding the mechanisms behind the possible clinical efficacy of such treatment. The review focuses successively on haemorrhagic shock, endotoxic shock and hypokalaemic metabolic alkalosis. How hypertonic saline solutions affect oxygen transport by haemoglobin is also considered. [less ▲]

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See detailSynthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas
Masereel, B.; Ouedraogo, R.; Dogne, J.-M. et al

in European Journal of Medicinal Chemistry (1997), 32

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See detailChanges in the Distribution Pattern of Galectin-1 and Galectin-3 in Human Placenta Correlates with the Differentiation Pathways of Trophoblasts
Maquoi, Erik ULg; van den Brule, F. A.; Castronovo, Vincenzo ULg et al

in Placenta (1997), 18(5-6, Jul-Aug), 433-9

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined ... [more ▼]

Human placentation is a complex biological phenomenon that results from precisely regulated interactions between cells and the extracellular matrix. Galectin- 1 and galectin-3 belong to a newly defined family of galactose-binding lectins that can bind several glycoconjugates such as the basement membrane glycoprotein laminin, and are involved in many biological events including cell adhesion. In this study, the expression of these two galectins in first and third trimester normal human placenta was examined using single and double immunohistochemical staining and specific antibodies for galectins and cytokeratins. Galectin-3 was detected in all trophoblastic lineages including villous cytotrophoblasts and extravillous trophoblasts (trophoblastic cell columns, infiltrating trophoblasts, endovascular trophoblasts and placental bed giant cells). On the contrary, galectin-1 distribution was restricted to endometrium. A reduction of galectin-3 expression was observed from the villous trophoblasts to the trophoblastic cell columns. This pattern correlated with the switch from a proliferative to a migratory phenotype. Galectin-1 and galectin-3 were both detected in maternal decidual cells. Our data demonstrate a specific pattern of galectin-1 and galectin-3 expression in trophoblastic tissue, and suggest these lectins could contribute to cell-cell and cell matrix interactions of trophoblast during placentation. [less ▲]

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See detailGlucose turnover in humans in the basal state and after intravenous glucose: a comparison of two models.
Overkamp, D.; Gautier, J. F.; Renn, W. et al

in American Journal of Physiology (1997), 273(2 Pt 1), 284-96

This study investigated the ability of two models to represent glucose kinetics in the basal steady state and during an intravenous glucose tolerance test (IVGTT). Six young nonobese male subjects were ... [more ▼]

This study investigated the ability of two models to represent glucose kinetics in the basal steady state and during an intravenous glucose tolerance test (IVGTT). Six young nonobese male subjects were studied after an overnight fast. Two bolus injections of [U-13C]glucose were given 150 min apart, the first without and the second together with concomitant injection of unlabeled glucose. [3-3H]glucose was constantly infused throughout the study and served to provide an independent means for evaluation of system responses. A linear time-invariant three-compartmental model and the two-compartment time-variant model proposed by Caumo and Cobelli were used to interpret measured time courses of [U-13C]glucose and to reconstruct endogenous glucose production and glucose removal. The ability of the two models to describe the glucose tracer time course was comparable. Simulation studies showed that the two-compartmental time-variant system better predicted measured [3-3H]glucose concentration profiles than did the three-compartmental time-invariant model. However, endogenous glucose production and the integral of excess glucose removal over basal during the IVGTT derived from the two models were almost identical. [less ▲]

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See detailThe effect of dispersion and atomisation conditions on the compaction response of silicon nitride granules
Destoop, Vincent; Mertens, Anne ULg; Hendrix, W. et al

in Key Engineering Materials [=KEM] (1997), 132-136

The relationship between the dispersion conditions of silicon nitride slurries and the compaction behaviour of spray dried granules is reported in the case of two commercial powders. Two parameters have ... [more ▼]

The relationship between the dispersion conditions of silicon nitride slurries and the compaction behaviour of spray dried granules is reported in the case of two commercial powders. Two parameters have been retained: the solid loading, varied between 10 and 30 vol.% and the degree of stability of the suspension, controlled by adjustment of the pH. [less ▲]

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See detailLa Belgique: Diversité territoriale
Merenne-Schoumaker, Bernadette ULg; Van der Haegen, H.; Van Hecke, E.

in Bulletin du Crédit Communal (1997), (202), 144

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques ... [more ▼]

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques entre 1981 et 1991. 155 cartes en couleurs. [less ▲]

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See detailLe Système d'informations sur la Biodiversité en Wallonie.
Dufrêne, Marc ULg

in Les cahiers des Réserves Naturelles RNOB (1997), 11

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See detailCirculation of the western Mediterranean: From global to regional scales
Beckers, Jean-Marie ULg; Brasseur, P.; Nihoul, Jacques ULg

in Deep-Sea Research Part II, Topical Studies in Oceanography (1997), 44(3-4), 531-549

A free-surface, three-dimensional, primitive equation model has been implemented with a horizontal resolution of 4.6 km to study the ocean circulation in the Gulf of Lions at time scales ranging from ... [more ▼]

A free-surface, three-dimensional, primitive equation model has been implemented with a horizontal resolution of 4.6 km to study the ocean circulation in the Gulf of Lions at time scales ranging from weeks to seasons. Numerical experiments have been conducted, in which the regional model is nested into a basin-scale model of the whole western Mediterranean. The global model is operated with a relatively coarse resolution (16 km) and provides boundary conditions at the open-sea boundaries of the regional domain. There is, however, no Feedback loop from the regional to the global model. The simulations are consistently driven with atmospheric fluxes computed from the output of the French PERIDOT meteorological forecasting system, between August 1988 and 1989. In addition to the initial conditions, in situ measurements of temperature and salinity are assimilated in the simulation of the general circulation, adopting a simple nudging technique to prevent an excessive drift of the model against climatology. The response of the regional model below and above the thermocline is discussed in the context of the prevailing meteorological situations. Some experiments give indications that a double-gyre system may develop from wind regimes that exhibit a cyclonic/anticyclonic wind stress curl. Advection-diffusion of passive tracers are also examined on the basis of the local hydrodynamic features, because this work has been conceived with the aim of determining the physical conditions in which ecological and biochemical processes develop at the interface between river mouths and the open ocean. (C) 1997 Elsevier Science Ltd. [less ▲]

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See detailLow Thiamine Diphosphate Levels in Brains of Patients with Frontal Lobe Degeneration of the Non-Alzheimer's Type
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; Wins, Pierre et al

in Journal of Neurochemistry (1997), 69(5), 2005-2010

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or ... [more ▼]

We compared the thiamine and thiamine phosphate contents in the frontal, temporal, parietal, and occipital cortex of six patients with frontal lobe degeneration of the non-Alzheimer's type (FNAD) or frontotemporal dementia with five age-, postmortem delay-, and agonal status-matched control subjects. Our results reveal a 40-50% decrease in thiamine diphosphate (TDP) in the cortex of FNAD patients, whereas thiamine monophosphate was increased 49-119%. TDP synthesizing and hydrolyzing enzymes were unaffected. The activity of citrate synthase, a mitochondrial marker enzyme, was decreased in the frontal cortex of patients with FNAD, but no correlation with TDP content was found. These results suggest that decreased contents of TDP, which is essentially mitochondrial, is a specific feature of FNAD. As TDP is an essential cofactor for oxidative metabolism and neurotransmitter synthesis, and because low thiamine status (compared with other species) is a constant feature in humans, a nearly 50% decrease in cortical TDP content may contribute significantly to the clinical symptoms observed in FNAD. This study also provides a basis for a trial of thiamine, to improve the cognitive status of the patients. [less ▲]

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See detailVieillissement normal, démence d'Alzheimer et mémoire de travail
Van der Linden, Martial ULg; Collette, Fabienne ULg; Andrès Bénito, Pilar

in Psychologie Française (1997), 42

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See detailPemphigus foliacé dans l'espèce équine : synthèse et description de 2 cas.
Amory, Hélène ULg; Beco, Luc; Desmecht, Daniel ULg et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailRelationships among estimates of inbreeding depression, dominance and additive variance for linear traits in Holsteins
Misztal, I.; Lawlor, T. J.; Gengler, Nicolas ULg

in Genetics, Selection, Evolution (1997), 29(4), 319-326

Estimates of dominance and additive variances were obtained for 14 linear traits. The data included 600 678 first parity records on 14 linear traits in Holsteins. The model included management groups, age ... [more ▼]

Estimates of dominance and additive variances were obtained for 14 linear traits. The data included 600 678 first parity records on 14 linear traits in Holsteins. The model included management groups, age at calving, additive and dominance effects, and regression on inbreeding percentage. The estimate of the dominance variance was 9.8% of the phenotypic variance for body depth: 8.0% for strength, 6.9% for stature, and was less than 5% for the remaining traits. The additive variance ranged from 12.2% for foot angle to 45.3% for stature. No clear relationship was found between the estimates of dominance and additive variance. larger negative estimates of the inbreeding depression were associated with higher estimates of the dominance variance. [less ▲]

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See detailUse Of Mycosphaerella Fijiensis Toxins For The Selection Of Banana Cultivars Resistant To Black Leaf Streak
Harelimana, Germain; Lepoivre, Philippe ULg; Jijakli, Haissam ULg et al

in Euphytica : International Journal of Plant Breeding (1997), 96(1), 125-128

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See detailInfluence du stade de maturité de la plante de maïs récoltée pour ensilage sur la composition, la digestibilité apparente, les caractéristiques de fermentation dans le rumen et les performances zootechniques chez le taurillon
Mayombo, Asangule Pierre; Dufrasne, Isabelle ULg; Hornick, Jean-Luc ULg et al

in Animal Research (1997), 46(1), 43-55

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de ... [more ▼]

Un maïs plante entière a été ensilé à trois stades de maturité différents (S1, S2, S3) correspondant à des teneurs respectives en matière sèche de 25,1 (S1), 29,8 (S2) et 32,3 % (S3). La production de matière sèche s'élevait à 10,7 ; 11,1 et 11,7 tonnes par hectare. Chacun de ces ensilages, distribué à des taureaux à l'engraissement, a été supplémenté par des pulpes séchées, du tourteau de soja, des sels minéraux et des vitamines. Le stade de maturité n'a pas affecté les teneurs en cendres, cendres insolubles, extrait éthéré ou protéines ; cependant une réduction significative de la teneur en fibre ADF a été enregistrée avec S3. La digestibilité de la matière sèche et de la matière organique de la ration mesurée in vivo sur des taureaux en cages à bilan ainsi que celle du maïs ensilage n'ont pas été non plus influencées par le stade de maturité. En revanche, la digestibilité de la fibre ADF a été significativement plus faible pour S3 par rapport à S1 et S2 (62,1 vs 67,2 ou 65,6 %, p < 0,05 pour la ration; 54,1 vs 63,3 ou 60,7 %, p < 0,001 pour le maïs). Quant aux potentialités du rumen à dégrader les aliments, il est à noter que la dégradabilité totale par la méthode in sacco des différents composants testés a été supérieure dans le rumen des animaux qui recevaient le maïs à teneur en matière sèche élevée. Il n'y a pas eu d'effets significatifs du stade de maturité sur les performances animales durant un essai de 5,5 mois dans le cas d'une alimentation ad libitum. A partir de l'indice de consommation, du gain total de poids vif et de la production de matière sèche par hectare, il était possible d'estimer que 13,8, 14,2 et 15,7 taurillons pouvaient être engraissés respectivement à partir des ensilages de maïs S1, S2 et S3 produits par ha. [less ▲]

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See detailMonoclonal Antibody Production - The Report And Recommendations Of Ecvam Workshop 23
Marx, U.; Embleton, Mj.; Fischer, R. et al

in Alternatives to Laboratory Animals (1997), 25(2),

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See detailNanoindentation and scanning force microscopy as a novel method for the characterization of tribological transfer films
Randall, N. X.; Bozet, Jean-Luc ULg

in Wear (1997), 212(1), 18-24

In conventional pin-on-disk testing of the tribological characteristics of two different materials in sliding contact, the main parameters of interest are notably the friction and wear properties of the ... [more ▼]

In conventional pin-on-disk testing of the tribological characteristics of two different materials in sliding contact, the main parameters of interest are notably the friction and wear properties of the material pair. However, when two bodies consisting of hard and soft materials respectively are subjected to such testing, the appearance of a transfer film, or third body, which can be a composite mixture of the two, is often observed. Until now the characterization of transfer films in terms of their mechanical properties has been hampered by their nonhomogeneous distribution across a tested surface, their small size, low thickness and the difficulty in accurately positioning a test probe such that the film properties can be measured independently from those of the substrate. In this paper a new method is introduced, consisting of nanoindentation and scanning force microscopy (SFM), which is capable of highly localized indentation testing of a specified sample site with high resolution imaging of the area prior to and after indentation. In this way the hardness and modulus of a transfer film can be obtained, as well as valuable surface topographical information concerning the material response to the indentation. Measurements are presented for the material pair A286/polyimide after testing on a pin-on-disk tribometer in ambient air and liquid nitrogen. Distinct variations in hardness between the transfer films and their contacting bodies have een observed and correlated to the wear behaviour and testing environment. (C) 1997 Elsevier Science S.A. [less ▲]

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See detailmorbidity in neonates afetr labour induction or cesarean section
Battisti, Oreste ULg; Bertrand, J. M.; Adant-François, A. et al

in vlaamse verenigong voor obstetrie en gynaecologie jaarboek (1997), 1

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See detailNote sous Cassation, 7 mai 1996
Orban, Lionel ULg

in Actualités du Droit (1997)

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See detailBankfull discharge recurrence interval in gravel bed rivers
Petit, François ULg; Pauquet, A.

in Earth Surface Processes & Landforms (1997)

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with ... [more ▼]

Bankfull discharge was identified in some 30 gravel-bed rivers representing in total c. 40 gauging stations. The catchment sizes vary from 4km2 to nearly 2700km2. Bankfull discharge values increases with basin size. In the case of gravel-bed rivers developed on an impermeable substratum, the following equation emerges: Qb=0·087 A1·044. Bankfull discharge recurrence interval was determined by fitting maximum annual floods (Ta) into Gumbel’s distribution and then using the partial duration series (Tp) in this same distribution. Recurrence interval is below 0·7 years (Tp) for small pebble-bed rivers developed on an impermeable substratum; it reaches 1·1 to 1·5 years when the catchment size of these rivers exceeds 250km2. Rivers incised in the soft schists of the Famenne show larger channel capacity at bankfull stage, a small width/depth ratio and thus higher recurrence intervals (1·4–5·3 years with Ta and 1–4·4 years with Tp). Baseflow-dominated gravel-bed streams and sandy or silty rivers experience less frequent bankfull discharges, with a recurrence interval higher than 2 or even 3 years (Tp). [less ▲]

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See detailBWGIC guidelines for training and quality control in adult interventional cardiology. Belgian Working Group of Invasive Cardiology.
Legrand, Victor ULg; Vrolix, M.; De Bruyne, B. et al

in Acta cardiologica (1997), 52(6), 507-14

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See detailThe Burden of Hypopituitarism in Adults after Pituitary Surgery
Van Roijen, L.; Beckers, Albert ULg; Stevenaert, Achille ULg et al

in Journal of Clinical Endocrinology and Metabolism (1997), 4(Suppl. B), 139-142

The burden of illness was assessed in 183 hypopituitary patients, with growth hormone deficiency, who had received pituitary surgery at the Centre Hospitalier Universitaire de Liège, Belgium. The Short ... [more ▼]

The burden of illness was assessed in 183 hypopituitary patients, with growth hormone deficiency, who had received pituitary surgery at the Centre Hospitalier Universitaire de Liège, Belgium. The Short-Form 36 (SF-36) was used to assess health status, and the Health and Labour Questionnaire was used to obtain data on production loss and reduced labout performance. Data on medical consumption were also collected. The overall response rate was 72 %. Hypopituitary patients reported a lower health status than that of the mean population in all but two dimensions of the SF-36 (bodily pain and physical functioning). A relativelu high percentage of hypopituitary patients reported being incapacitated for paid employment, and those in paid employment reported higher absence rates compared with reference data. However, while at work there was no indication that hypopituitary patients perform less well due to health problems than the average population. Healthcare costs for hypopituitary patients who had undergone pituitary surgery were higher than for the reference population. [less ▲]

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See detailA la mémoire de Daniel P. Bobon, Mafhoud Boucebci, Amadeo Sanchez Blanque, Jean Mirel
Mormont, Christian ULg

in Acta Psychiatrica Belgica (1997), 97(Suppl. 1), 2-7

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