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See detailImplication de la neurohypophyse dans le stress psychique
Scantamburlo, Gabrielle ULg; Ansseau, Marc ULg; Legros, Jean-Jacques ULg

in Encéphale (L') (2001), 27(3, May-Jun), 245-59

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various ... [more ▼]

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various psychiatric diseases such an anorexia nervosa, bipolar disorder, schizophrenia and obsessive-compulsive disorder. AVP and OT are secreted into the hypophyseal portal circulation by neurons which project from the paraventricular nucleus to the external zone of the median eminence. AVP and OT-containing neurons in the suprachiasmatic and paraventricular nuclei project to limbic areas, including the hippocampus, the subiculum, the ventral nucleus of the amygdala and the nucleus of the diagonal band. Specific AVP receptors which are pharmacologically different from the pressor and antidiuretic AVP receptors have been found in the anterior pituitary. OT receptors have been identified in a variety of forebrain sites. The neurohypophyseal secretion is regulated by the cholinergic muscarinic, histaminergic and beta-adrenergic systems. Stress alters the secretion of one or more of the hypothalamic factors which interact at the pituitary to increase the secretion of ACTH. AVP and OT have been shown to modulate the effect of Corticotropin-Releasing Factor (CRF) on ACTH secretion and appear to play a key role in mediating the ACTH response to stress. Although AVP is a relatively weak secretagogue for ACTH, it markedly potentiates the activity of CRF both in vitro and in vivo. The role of OT is more complex. In vitro, OT stimulates ACTH release at high doses whereas in human it inhibits ACTH secretion at low doses. The type of stressor appear to determine the relative importance of these secretatogues in ACTH response. Several recent studies indicate that psychological stressors display a similar degree of variety of secretagogue release patterns as was found earlier for physical stressors. A bewildering array of technique produces a bewildering array of conclusions. In rats, OT may be an important secretagogue during a novel stimulus, whereas the role for AVP is less clear. Indeed two studies out of ten suggest a stimulating role for AVP. In response to frustration and submission, OT and AVP are secreted. Regarding social isolation, results are difficult to interpret and the role of AVP could be species-dependent. In contrast plasma OT levels do not change. After restraint, ACTH release is primarily mediated by the active increase of OT and AVP does not appear to play a role. When restraint is associated with moderate levels of physical components and during immobilisation, all two secretagogs are involved in the ACTH response. With fear, ACTH response appears to be driven by OT. In humans, one study indicates that high emotionality women increase plasma OT in response to uncontrollable noise. Various neuroendocrine dysregulations have been observed in psychiatric disease. Either an increase or a decrease of the hypothalamic-pituitary-adrenal (HPA) function have been described in several illnesses. Effects of OT appear to be reciprocal to the effects of AVP. OT has been called the "amnestic" neuropeptide due to its capacity to attenuate memory consolidation and retrieval. AVP exhibits a central activating action on mood, memory and selective attention. Underweight patients with anorexia nervosa have abnormally high levels of centrally directed AVP and reduced OT levels. These modifications could enhance the retention of cognitive distortions of aversive consequences of eating. Patients with bipolar disorder show a biphasic secretion of AVP. Depressive episodes are associated with decreased vasopressinergic activity whereas manic episodes involve an increased release. AVP might be responsible for an increased catecholamine activity. In addition, lithium could act as an antagonist to AVP. In schizophrenic patients, studies using the apomorphine stimulation suggest increased oxytoninergic and decreased vasopressinergic functions. These findings are consistent with the beneficial role of AVP on schizophrenic symptoms noted in several trials. The increased OT could be responsible for "positive" symptomatology such as delusions and hallucinations. Obsessive compulsive disorder (OCD) includes a range of cognitive and behavioral disturbances that could be influenced by OT. In animals, several studies have emphasized the role of AVP in promoting repetitive grooming behaviors and maintaining conditioned response to aversive stimuli. In OCD patients, one study have reported that AVP/OT ratio was negatively correlated with symptom severity. However, an independent report found similar AVP concentrations in OC patients without a personal or family history of tic disorder and in normal subjects. Whether these modifications are only a consequence of the central disturbances or whether those peptides could participate in the pathogenesis of these affections remains to be elucidated. [less ▲]

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See detailSpectroscopic evidence for high-altitude Aurora at Jupiter from Galileo Extreme Ultraviolet Spectrometer and Hopkins Ultraviolet Telescope observations
Ajello, Joseph M.; Shemansky, D. E.; Pryor, Wayne R. et al

in Icarus: International Journal of Solar System Studies (2001), 152(1), 151-171

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the ... [more ▼]

The Galileo Extreme Ultraviolet Spectrometer (EUVS) and the Hopkins Ultraviolet Telescope (HUT) acquired UV spectra of Jupiter Aurora in the period from 1995 through 1997, The EUVS spectra spanned the wavelength range 540-1280 Angstrom and the HUT spectra measured the extreme ultraviolet and far ultraviolet (EUV + FUV) wavelength range 830-1850 Angstrom. Both sets of spectra present evidence of high-altitude, optically thin H-2 band emissions from the exobase region, The analysis of the UV spectra with a two-stream electron transport model and a jovian model auroral atmosphere indicates that the primary electron flux is composed of both soft and hard electrons with characteristic energies in the soft electron energy range of 20-200 eV and the hard electron range of 5-100 keV, The soft electron flux causes enhanced EUV emission intensities below 1100 Angstrom. The soft electron flux may explain the high temperature of the upper atmosphere above the homopause as measured from Il: rovibrational temperatures in the IR. For the deep aurora, a high primary characteristic energy above 5 keV is known to be present. The Galileo Energetic Particle Detector (EPD) has measured the electron distribution functions for energies above 15 keV in the middle magnetosphere. The high-energy distribution functions can be modeled by a combination of Maxwellian and kappa distributions. However, the EUV (800-1200 Angstrom) portion of the HUT spectrum cannot be modeled with a single distribution of hard electrons as was possible in the past for the FUV (1200-1650 Angstrom) spectrum measured by itself, The combination of EUV and FUV spectral observations by HUT serves to identify the amount of soft electron flux relative to the hard primary flux required to produce the high-altitude aurora in the neighborhood of the exobase, (C) tool academic Press. [less ▲]

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See detailMigraine
Sandor, Peter S.; Agosti, Reto; Schoenen, Jean ULg

in Pain Clinical Updates (2001), 9

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See detailProcollagen II amino propeptide processing by ADAMTS-3. Insights on dermatosparaxis.
Fernandes, R. J.; Hirohata, S.; Engle, J. M. et al

in Journal of Biological Chemistry (2001), 276(34), 31502-9

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause ... [more ▼]

The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause dermatosparaxis in cattle and the Ehlers-Danlos syndrome (dermatosparactic type) in humans by preventing proteolytic excision of the N-propeptide of procollagen I. We have found that procollagen II is processed normally in dermatosparactic nasal cartilage, suggesting the existence of another N-propeptidase(s). We investigated such a role for ADAMTS-3 in Swarm rat chondrosarcoma RCS-LTC cells, which fail to process the procollagen II N-propeptide. Stable transfection of RCS-LTC cells with bovine ADAMTS-2 or human ADAMTS-3 partially rescued the processing defect, suggesting that ADAMTS-3 has procollagen II N-propeptidase activity. Human skin and skin fibroblasts showed 30-fold higher mRNA levels of ADAMTS-2 than ADAMTS-3, whereas ADAMTS-3 mRNA was 5-fold higher than ADAMTS-2 mRNA in human cartilage. We propose that both ADAMTS-2 and ADAMTS-3 process procollagen II, but ADAMTS-3 is physiologically more relevant, given its preferred expression in cartilage. The findings provide an explanation for the sparing of cartilage in dermatosparaxis and, perhaps, for the relative sparing of some procollagen I-containing tissues. [less ▲]

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See detailVies et Miracles de Domitien Deuxième partie
George, Philippe ULg

in Analecta Bollandiana : Revue Critique d’Hagiographie = A Journal of Critical Hagiography (2001), CXIX

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See detailGeometrical considerations for evaluation of reserve design.
Bogaert, Jan ULg; Salvador-Van Eysenrode, D; Van Hecke, P et al

in Web Ecology (2001), (2), 65-70

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See detailValue of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of Cancer 58881 randomized phase III trial.
Millot, F; Suciu, S; Philippe, N et al

in Journal of Clinical Oncology (2001), 19

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV ... [more ▼]

PURPOSE: The European Organization for Research and Treatment of Cancer 58881 study was designed to test in a prospective multicentric randomized trial the value of high-dose (HD) intravenous (IV) cytarabine (Ara-C) added to HD IV methotrexate (MTX) to reduce the incidence of CNS and systemic relapses in children with increased-risk acute lymphoblastic leukemia (ALL) or stage III and IV lymphoblastic lymphoma treated with a Berlin-Frankfurt-Munster (BFM)-based regimen. PATIENTS AND METHODS: After completion of induction-consolidation phase, children with increased-risk (risk factor > 0.8 or T-lineage) ALL or stage III and IV lymphoblastic lymphoma were randomized to receive four courses of HD MTX (5 g/m(2) over 24 hours every 2 weeks) and four intrathecal administrations of MTX (Arm A) or the same treatment schedule with additional HD IV Ara-C (1 g/m(2) in bolus injection 12 and 24 hours after the start of each MTX infusion) (Arm B). RESULTS: Between January 1990 and January 1996, 653 patients with ALL (593 patients) or lymphoblastic lymphoma (60 patients) were randomized: 323 were assigned to Arm A (without Ara-C) and 330 to Arm B (with Ara-C). A total of 190 events (177 relapses and 13 deaths without relapse) were reported, and the median follow up was 6.5 years (range, 2 to 10 years). The incidence rates of CNS relapse were similar in both arms whether isolated (5.6% and 3.3%, respectively) or combined (5.3% and 4.6%, respectively). The estimated 6-year disease-free survival (DFS) rate was similar (log-rank P =.67) in the two treatment groups: 70.4% (SE = 2.6%) in Arm A and 71.0% (SE = 2.5%) in Arm B. The 6-year DFS rate was similar for ALL and LL patients: 70.2% (SE = 1.9%) versus 76.3% (SE = 5.6%). CONCLUSION: Prevention of CNS relapse was satisfactorily achieved with HD IV MTX and intrathecal injections of MTX in children with increased-risk ALL or stage III and IV lymphoblastic lymphoma treated with our BFM-based treatment protocol in which cranial irradiation was omitted. Disappointingly, with the dose schedule used in this protocol, HD Ara-C added to HD MTX, although well tolerated, failed to further decrease the incidence of CNS relapse or to improve the overall DFS. [less ▲]

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See detailmarchés publics et économie sociale: l'union impossible?
Navez, Françoise ULg; Durviaux, Ann-Lawrence ULg

in Actualités du Droit (2001), 2

L'article envisage la question de l'introduction de considérations sociales dans les marchés publics: les obstacles et la technique de la clause sociale.

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See detailSubclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements.
Sandor, P. S.; Mascia, A.; Seidel, L. et al

in Annals of Neurology (2001), 49(5), 668-72

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum ... [more ▼]

Mutations in the CACNA1A gene can cause familial hemiplegic migraine (FHM) and/or cerebellar ataxia CACNA1A codes for the alpha1 subunit of P/Q-Ca2+ channels and is highly expressed in the cerebellum. Using a pointing paradigm and infrared optoelectronic tracking system, we found subclinical hypermetria and other subtle cerebellar signs in the common forms of migraine. These were more pronounced in migraine with than without aura. Whether this reflects involvement of Ca2+ channel genes in the common types of migraine needs to be investigated by genetic analyses. [less ▲]

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See detailRole of interface deformations in Benard-Marangoni instability
Lebon, Georgy ULg; Dauby, Pierre ULg; Regnier, Vincent

in Acta Astronautica (2001), 48(5-12), 617-627

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See detailLes surcoûts de l’étalement urbain en Wallonie
Halleux, Jean-Marie ULg

in Etudes Foncières (2001), (94), 18-21

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See detailSynergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
Carmeliet, Peter; Moons, Lieve; Luttun, Aernout et al

in Nature Medicine (2001), 7(5), 575-583

Vascular endothelial growth factor (VEGF) stimulates angiogenesis by activating VEGF receptor-2 (VEGFR-2). The role of its homolog, placental growth factor (PlGF), remains unknown. Both VEGF and PlGF bind ... [more ▼]

Vascular endothelial growth factor (VEGF) stimulates angiogenesis by activating VEGF receptor-2 (VEGFR-2). The role of its homolog, placental growth factor (PlGF), remains unknown. Both VEGF and PlGF bind to VEGF receptor-1 (VEGFR-1), but it is unknown whether VEGFR-1, which exists as a soluble or a membrane-bound type, is an inert decoy or a signaling receptor for PlGF during angiogenesis. Here, we report that embryonic angiogenesis in mice was not affected by deficiency of PlGF (Pgf -/-). VEGF-B, another ligand of VEGFR-1, did not rescue development in Pgf -/- mice. However, loss of PlGF impaired angiogenesis, plasma extravasation and collateral growth during ischemia, inflammation, wound healing and cancer. Transplantation of wild-type bone marrow rescued the impaired angiogenesis and collateral growth in Pgf -/- mice, indicating that PlGF might have contributed to vessel growth in the adult by mobilizing bone-marrow−derived cells. The synergism between PlGF and VEGF was specific, as PlGF deficiency impaired the response to VEGF, but not to bFGF or histamine. VEGFR-1 was activated by PlGF, given that anti-VEGFR-1 antibodies and a Src-kinase inhibitor blocked the endothelial response to PlGF or VEGF/PlGF. By upregulating PlGF and the signaling subtype of VEGFR-1, endothelial cells amplify their responsiveness to VEGF during the 'angiogenic switch' in many pathological disorders. [less ▲]

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See detailA comparison of blade tip timing data analysis methods
Carrington, Ian B; Wright, Jan Robert; Cooper, Jonathan E et al

in Proceedings of the Institution of Mechanical Engineers - Part G - Journal of Aerospace Engineering (2001), 215(6), 301-312

The experimental determination of the vibration characteristics of rotating engine blades is very important for fatigue failure considerations. One of the most promising techniques for measuring the ... [more ▼]

The experimental determination of the vibration characteristics of rotating engine blades is very important for fatigue failure considerations. One of the most promising techniques for measuring the frequency of blade vibrations is blade tip timing. In this paper, three vibration analysis methods were specifically formulated and applied to the tip timing problem for the first time, using data obtained from a simple mathematical blade tip timing simulation. The results from the methods were compared statistically in order to determine which of the techniques is more suitable. One of the methods, the global autoregressive instrumental variables approach, produced satisfactory results at realistic noise levels. However, all of the techniques produced biased results under certain circumstances. [less ▲]

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See detailLe dispositif d'évaluation externe en Communauté française de Belgique
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 195-218

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See detailThe behavioral effects of acute and chronic JL 13, a putative antipsychotic, in Cebus non-human primates
Casey, Daniel; Bruhwyler, Jacques; Delarge, Jacques et al

in Psychopharmacology (2001), 157

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See detailNovel inhibitors of the sodium-calcium exchanger: benzene ring analogues of N-guanidino substituted amiloride derivatives
Rogister, F.; Laeckmann, D.; Plasman, P.-O. et al

in European Journal of Medicinal Chemistry (2001), 36

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See detailDonnées récentes sur la pathogenèse de l'infection à Microsporum canis chez les carnivores domestiques
Brouta, F.; Descamps, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailRole Of The Proline-Rich Motif Of Bovine Leukemia Virus Transmembrane Protein Gp30 In Viral Load And Pathogenicity In Sheep
Reichert, M.; Winnicka, A.; Willems, Luc ULg et al

in Journal of Virology (2001), 75(17),

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See detailLow TSH requirement and goiter in transgenic mice overexpressing IGF-1 and IGF-1R in the thyroid gland
Clément, S.; Refetoff, S.; Robaye, B. et al

in Endocrinology (2001), 142(12), 5131-5139

Through the cAMP signaling pathway, TSH stimulates thyroid follicular cell proliferation, differentiation, and function. Although the autocrine production of IGF-I in the thyroid gland suggests an ... [more ▼]

Through the cAMP signaling pathway, TSH stimulates thyroid follicular cell proliferation, differentiation, and function. Although the autocrine production of IGF-I in the thyroid gland suggests an important physiological function for this factor in these processes, the exact role of the IGF-I/IGF-I receptor system in vivo remains unclear. Although the mitogenic action of TSH requires the presence of IGF-I or insulin in primary culture of dog and human thyroid cells, IGF-I has an effect equal to and independent of the effect of TSH on cell proliferation in rat thyroid cell lines and may even be the main growth regulator in this case. To investigate the in vivo function of the IGF-I/IGF-I receptor system, transgenic mice overexpressing human IGF-I, IGF-I receptor, or both in the thyroid were generated. Adult transgenic mice did not present external signs of thyroid dysfunction, but mice overexpressing both transgenes had significantly increased gland weight and follicular lumen area. A decreased TSH level together with a slightly increased serum T4 concentration and increased thyroidal iodine uptake were also observed, suggesting that IGF-I and IGF-I receptor stimulate thyroid function to some extent in vivo [less ▲]

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See detailEugène Monseur (1860-1912)
Boutier, Marie-Guy ULg

in Wallonnes : Chronique de la Société de Langue et de Littérature Wallonnes (2001), (1),

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See detail« En quête d’un nouveau droit du travail »
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2001), Vol. XIV

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See detailLa libre circulation des personnes dans l'Union européenne (1er janvier - 31 décembre 2000)
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2001), 9(3), 65-73

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See detailc-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.
Minet, E.; Michel, G.; Mottet, Denis ULg et al

in Experimental Cell Research (2001), 265(1), 114-24

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors ... [more ▼]

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors which participate in the adaptive response of the cells to hypoxia. Among these transcription factors, AP-1 is rapidly activated by hypoxia and triggers bFGF, VEGF, and tyrosine hydroxylase gene expression. However, the mechanisms of AP-1 activation by hypoxia are not well understood. In this report, we studied the events leading to AP-1 activation in hypoxia. We found that c-jun protein accumulates in hypoxic HepG2 cells. This overexpression is concomitant with c-jun phosphorylation and JNK activation. Moreover, we showed that AP-1 is transcriptionally active. We also observed that AP-1 transcriptional activity is inhibited by a MEKK1 dominant negative mutant. Moreover, the MEKK1 dominant negative mutant as well as deletion of the AP-1 binding sites within the c-jun promoter inhibited the c-jun promoter activation by hypoxia. All together, these results indicate that, in hypoxic HepG2 cells, AP-1 is activated through a JNK-dependent pathway and that it is involved in the regulation of the c-jun promoter, inducing a positive feedback loop on AP-1 activation via c-jun overexpression. [less ▲]

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See detailInfluence du régime d’administration continu ou discontinu d’acétate de nomégestrol sur l’apoptose des cellules mammaires
Van den Brule, F; DESREUX, Joëlle ULg; BELIARD, Aude ULg et al

in Reproduction Humaine et Hormones (2001), 15

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See detailÉvolution des accessibilités et des mobilités des localisations commerciales
Merenne-Schoumaker, Bernadette ULg

in Travaux de l’Institut de Géographie de Reims (2001), 27(107-108), 7-23

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly ... [more ▼]

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly, the definition of the concepts of accessibility and mobility as well as the distance; secondly, analysis of the role of these two concepts in the commercial field and the their most evident recent evolutions; lastly, research into corresponding links. On the basis of this work, everything indicates the priority of mobility over accessibility as well as very close relations between the mutations of urbanized territories and the installation of the new commercial framework, which is strongly governed by car mobility. [less ▲]

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See detailIncinérateurs, crise dioxine et risques sanitaires pour la population belge
Bernard; Fierens; Mairesse et al

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (2001), 1-6

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See detailGénéralisation de l'apprentissage d'une langue moderne à l'école primaire ; première analyse de la situation
Straeten, M.; Blondin, Christiane ULg

in Point sur la Recherche en Education (Le) (2001), 19

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See detailÉtude de l'influence de l'hydrodynamique sur une bactérie filamenteuse par analyse d'images
Groslambert, Sylvie ULg; Blacher, Silvia ULg; Crine, Michel ULg

in Récents Progrès en Génie des Procédés (2001), 78(18), 153-158

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See detailUretere retrocave chez un enfant de dix ans.
Kakanou, A.; NCHIMI LONGANG, Alain ULg; Ghuysen, M. S. et al

in Annales de Chirurgie (2001), 126(2), 156-8

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral ... [more ▼]

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral obstruction generally leads to the deterioration of renal function during adulthood. Treatment depends on the symptomatology in question, and surgical management should be as conservative as possible. [less ▲]

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See detailRegime alimentaire du Grand-Duc du désert, Bubo ascalaphus, dans la réserve naturelle de Mergueb (M'Sila, Algérie)
Biche, Mohamed; Sellami, Medhi; Libois, Roland ULg et al

in Alauda (2001), 69(4), 554-557

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical ... [more ▼]

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical basis (82 %) as well as in term of biomass (96 %) was Meriones shawi trouessarti (Gerbillidae). Other preys included Jaculus orientalis (Dipodidae), and two insectivores: Crocidura russula and Hemiechinus aethiopicus. Among the avifauna, only the Spanish sparrow (Passer hispaniolensis) was a significant part of the Eagle owl dietn especially in spring. Arthropods were represented by Scarabeidae in spring and Scorpionidae in summer but they played a minor role in the food of the Eagle owl. The originality of this diet lies in the absence of Brown hare (Lepus capensis) and the presence of only one specimen of the desert hedgehog. Although its food spectrum was very narrow in this site, the Eagle owl can be regarded as opportunistic as it concentrated on the most available prey: Meriones shawi. [less ▲]

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See detailA Parametric Distance Function Approach for Malmquist Productivity Index Estimation
Fuentes, Hugo J.; Grifell-Tatjé, Emili; Perelman, Sergio ULg

in Journal of Productivity Analysis (2001), 15

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a ... [more ▼]

Malmquist indexes of productivity are generally estimated using index number techniques or non-parametric frontier approaches. The aim of this paper is to showthat Malmquist indexes can be estimated in a similar way using parametric-deterministic or parametric-stochastic frontier approaches. To allow a multi-output multi-input technology and for technical change in production, we adopt an output distance function which is specified in a translog form. We then show that using the estimated parameters, several radial distance functions can be calculated and combined in order to estimate and decompose the productivity index. Finally, this approach is applied to a panel of Spanish insurance companies. The main results confirm those generally obtained for financial services: very low rates of growth and technical change in spite of a rapid deregulation process and expansion of activity. [less ▲]

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See detailHuman - ovine comparative sequencing of a 250 kilobase imprinted domain encompassing the callipyge (clpg) gene and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11 and MEG8
Charlier, Carole ULg; SEGERS, Karin ULg; Wagenaar, D. et al

in Genome Research (2001), 11

Two ovine BAC clones and a connecting long-range PCR product, jointly spanning ∼250 kb and representing most of theMULGE5-OY3 marker interval known to contain the clpglocus, were completely sequenced. The ... [more ▼]

Two ovine BAC clones and a connecting long-range PCR product, jointly spanning ∼250 kb and representing most of theMULGE5-OY3 marker interval known to contain the clpglocus, were completely sequenced. The resulting genomic sequence was aligned with its human ortholog and extensively annotated. Six transcripts, four of which were novel, were predicted to originate from within the analyzed region and their existence confirmed experimentally: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8. RT-PCR experiments performed on a range of tissues sampled from an 8-wk-old animal demonstrated the preferential expression of all six transcripts in skeletal muscle, which suggests that they are under control of common regulatory elements. The six transcripts were also shown to be subject to parental imprinting: DLK1, DAT, andPEG11 were shown to be paternally expressed and GTL2,antiPEG11, and MEG8 to be maternally expressed. [less ▲]

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See detailAn overlay tree building control protocol
Mathy, Laurent ULg; Canonico, R.; Hutchison, D.

in Networked Group Communication (2001)

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See detailBreakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes.
Berghmans, S.; SEGERS, Karin ULg; Shay, T. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (2001), 12(2), 183-5

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See detailGérer l'hétérogénéité des élèves : Méthodes de regroupement des élèves dans l'enseignement obligatoire
Monseur, Christian ULg; Demeuse, Marc ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (7-8), 25-52

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See detailQuantitative short-term study of Anal sphincter function after chemoradiation for rectal cancer
Gervaz, Pascal; Rotholtz, Nicolas; Pisano, Michele et al

in Langenbeck's Archives of Surgery (2001), 136

Hypothesis: Pelvic irradiation adversely affects anal sphincter function after proctectomy with coloanal anastomosis for low rectal and middle rectal (,10 cm from the anal verge) tumors. Design: Case ... [more ▼]

Hypothesis: Pelvic irradiation adversely affects anal sphincter function after proctectomy with coloanal anastomosis for low rectal and middle rectal (,10 cm from the anal verge) tumors. Design: Case-control study. Setting: Private, tertiary care referral center. Patients: Patients treated for low rectal adenocarcinoma between January 1, 1994, and October 31, 1999. Interventions: Anal manometric data were prospectively collected at the time of initial diagnosis and before ileostomy closure. Main Outcome Measures: Mean and maximum resting pressures (RPs) and squeeze pressures, threshold volume for sensation, and maximal tolerable volume. Results: Twenty-three patients in the surgery group and 19 in the chemoradiotherapy group were considered for [less ▲]

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See detailAnticyclonic eddies in the deep eastern Black Sea in summer-autumn 1999 (satellite and ship-borne observations
Ginzburg, Anna I.; Zatsepin, Andrey; Kostianoy, Andrey G. et al

in Earth Observation and Remote Sensing (2001), 5

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See detailOral vitamin C attenuates acute ischaemia-reperfusion injury in skeletal muscle.
Kearns, S. R.; Moneley, D.; Murray, P. et al

in Journal of Bone & Joint Surgery, British Volume (2001), 83(8), 1202-6

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was ... [more ▼]

Ischaemia-reperfusion injury (IRI) is caused by endothelial and subendothelial damage by neutrophil-derived oxidants. Vitamin C is an antioxidant which attenuates endothelial injury after IRI. Our aim was to evaluate the effect of oral vitamin C in the prevention of IRI in skeletal muscle. We used a model of cross-clamping (3 hours) and reperfusion (1 hour) of the cremaster muscle in rats. Muscle function was assessed electrophysiologically by electrical field stimulation. Infiltration by neutrophils was determined by the activity of tissue myeloperoxidase (MPO) and tissue oedema by the wet-to-dry ratio. Neutrophil respiratory burst activity was measured in control animals and groups pretreated with vitamin C. IRI significantly decreased muscle function and increased muscle neutrophil MPO activity and muscle oedema. Pretreatment with vitamin C preserved muscle function and reduced tissue oedema and neutrophil infiltration. Neutrophil respiratory burst activity was reduced in the group treated with vitamin C compared with the control group. We conclude that pretreatment with oral vitamin C protects against acute muscle IRI, possibly by attenuating neutrophil respiratory burst activity. [less ▲]

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See detailPalladium-silver sol-gel catalysts for selective hydrodechlorination of 1,2-dichloroethane into ethylene III. Kinetics and reaction mechanism
Heinrichs, Benoît ULg; Schoebrechts, Jean-Paul; Pirard, Jean-Paul ULg

in Journal of Catalysis (2001), 200(2), 309-320

The kinetics of selective hydrodechlorination of 1,2-dichloro-ethane into ethylene over a Pd-Ag/SiO2 catalyst is studied. Kinetic data at 573, 596, and 647 K have been obtained by means of experimental ... [more ▼]

The kinetics of selective hydrodechlorination of 1,2-dichloro-ethane into ethylene over a Pd-Ag/SiO2 catalyst is studied. Kinetic data at 573, 596, and 647 K have been obtained by means of experimental designs in the space of the partial pressures of the four components influencing kinetics, that is, 1,2-dichloroethane, hydrogen, ethylene, and hydrogen chloride. One model among the numerous ones examined allows us to represent correctly the experimental data. Ii: corresponds to the following mechanism: dechlorination of 1,2-dichloroethane into ethylene occurs on silver through dissociative adsorption with successive breaking of the two C-Cl bonds and desorption of C2H4. Thanks to its activation power of hydrogen by dissociative chemisorption, palladium present at the surface of the alloy supplies hydrogen atoms for regeneration of the chlorinated silver surface into metallic silver. The presence of hydrogen adsorbed on Pd also causes the undesired ethylene hydrogenation leading to a loss of olefin selectivity. (C) 2001 Academic Press. [less ▲]

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See detailColomb interactions and the 17 August 1999 Izmit, Turkey earthquake
King, G. C. P.; Hubert, Aurelia ULg; Nalbant, S. S. et al

in Comptes Rendu de l’Académie des Sciences de Paris - Série 2. Sciences de la terre et des planètes (2001), 333(rie 2. Sciences de la terre et des planètes), 557-569

At 00:02 GMT (03:02 local time) on 17 August, 1999 a magnitude 7.4 (Ms) earthquake occurred 100 km east of Istanbul causing extensive destruction. The event was expected and several scientists have ... [more ▼]

At 00:02 GMT (03:02 local time) on 17 August, 1999 a magnitude 7.4 (Ms) earthquake occurred 100 km east of Istanbul causing extensive destruction. The event was expected and several scientists have published and attempted to publicize the danger. A paper on stress interactions for NW Turkey (J. Geophys. Res. 103 (1998) 24466–24469) concluded that “by combining the stress change map with the map of active faulting, likely locations for the occurrence of future earthquakes can be refined; faults in the Izmit Bay area, the western part of Biga Peninsula, the Saroz Gulf and a part of western Sea of Marmara must be regarded as posing a specific hazard”. An extension of that study is described here. It is shown that the Izmit (1999) earthquake loaded faults both to the east and west of the Izmit rupture. About three months after the Izmit event an M 7.2 earthquake occurred with an epicenter at Duzce extending the Izmit rupture to the east. In the Marmara Sea, west of Izmit, faults have been loaded by between 1 and 5 bar; 5 to 30 % of typical earthquake stress drops in the region suggesting the likelihood of a future event. The risk of a major event on a fault depends not just on stress increases associated with an individual earthquake, but also on the longer-term earthquake history and on tectonic loading. The roles of both are examined over two time periods from 1900 to 1999 and 1700 to 1999. Whatever interpretation we place on the data we conclude that one or two events as great or greater than the recent one is likely to occur within the next few decades near to the northern coast of the Marmara Sea [less ▲]

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See detailBinding and multiple instantiation in a distributed network of spiking nodes
Sougné, Jacques ULg

in Connection Science (2001), 13(2), 99-126

An implementation of a distributed connectionist network of spiking neuron-like elements is presented. Spiking nodes fire at a precise moment and transmit their activation, with particular strenghts and ... [more ▼]

An implementation of a distributed connectionist network of spiking neuron-like elements is presented. Spiking nodes fire at a precise moment and transmit their activation, with particular strenghts and delays, to nodes connected to them. Wen the potential of the node reaches a particular threshold, it emits a spike. Thereafter, the potential is reset to a resting value. The receiving nodes accumulate potential, but also, slowly lose their potential through decay. As with real neurons, after firing there is a short refractory period during which the node will be completely insensitive to incoming signals, after which its sensitivity will slowly increase. Precise timing properties are used to represent symbols in a distributed manner and also to solve the problems of variable binding and multiple instantiation. Several predictions about human short-term memory, predicate processing, complex reasoning and multiple instantiation arise from this model. This network shows how symbolic processing can be achieved using neurobiologically and psychologically plausible mechanisms that also have the advantages of generalization and noise tolerance found in connectionist networks. [less ▲]

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See detailInsémination artificielle des vaches ‘Azawak’ et taurin ‘Gourunsi’ au Burkina Faso
Zongo, M.; Boly, H.; Sawadogo, L. et al

in Tropicultura (2001), 19(2), 75-78

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine ... [more ▼]

La synchronisation des chaleurs et la fertilité en insémination artificielle des zébus ‘Azawak’ (Bos indicus, n = 66) et des taurins ‘Gourunsi’ (Bos taurus, n = 20) ont été appréciées en zone périurbaine soudano-sahélienne de Ouagadougou au Burkina Faso. La synchronisation a été effectuée avec des implants sous cutanés de progestagène placés sous la peau de l’oreille pendant 10 jours. Le traitement a été complété par l’injection de prostaglandine F2 et de PMSG, respectivement au 8ième et au 10ième jours de la pose de l’implant. Le taux d’œstrus induits observés par l’éleveur était de 94,2% dans les 48 heures qui suivaient le retrait de l'implant. Il variait significativement (P<0,05) selon les groupes zébus ‘Azawak’ et taurins ‘Gourunsi’ (100% et 75%, respectivement). Les taux de fertilité, déterminés par palpation rectale chez les zébus ‘Azawak’ et les taurins ‘Gourunsi’, ont été respectivement 24,2% et 10%. La fertilité a varié selon le moment de l’insémination: lorsque les femelles étaient inséminées 36 à 48 heures après le retrait de l’implant, les taux de fertilité ont été faibles (0 à 12,5% chez les taurins ‘Gourunsi’ et les zébus ‘Azawak’, respectivement). Par ailleurs, lorsque les inséminations étaient réalisées 24 à 36 heures après le retrait de l’implant, les taux de fertilité ont été respectivement de 50% et 42,3%. [less ▲]

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See detailProgramme international pour le suivi des acquis des élèves (PISA) de l'OCDE
Lafontaine, Dominique ULg; Baye, Ariane ULg; Matoul, Anne ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), 7-8(7-8), 53-57

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See detailNicardipine Protocol for Cabg Using the Radial Artery Clinical and Angiographic Data
RADERMECKER, Marc ULg; Grenade, Thierry ULg; Cao-Thian, S. K. et al

in Acta Chirurgica Belgica (2001), 101(4, Jul-Aug), 185-9

The routine use of arterial grafts in coronary surgery is facilitated by peroperative adjunction of antispasmodic drug to reduce the event of spasm. Diltiazem has been favoured in most clinical studies ... [more ▼]

The routine use of arterial grafts in coronary surgery is facilitated by peroperative adjunction of antispasmodic drug to reduce the event of spasm. Diltiazem has been favoured in most clinical studies devoted to the radial artery graft. The aim of this study was to assess the efficacy of a spasm preventing protocol associating hydrostatic dilation of the graft with a diluted solution of papaverine and nicardipine infusion, starting preoperatively and continued postoperatively in i.v. and per os forms. Between September 1996 and March 1997, a consecutive series of 50 patients underwent myocardial revascularization using the radial artery. The radial artery was prepared by hydrostatic dilation with papaverine (1%) and nicardipine was administrated at 0.25 microgram/kg/min and titrated according to the arterial systemic pressure. Operative mortality was 4% (sepsis). There was no evidence of perioperative MI nor hypoperfusion syndrome. Mean CKMB level at 18 hours was 36 micrograms/l. No ischaemic anomalies of the ECG were detected. Angiography performed in the last 20 patients showed a 98% (51/52) permeability rate for all graft; 19/20 radial grafts (95%) were patent. One radial graft presented a 50% stenosis at the proximal anastomosis, and another a moderate spasm (40%) in the middle part of the conduit. This study confirms that the radial artery conduit can be used with satisfactory results for routine coronary artery bypass. The use of nicardipine allows the control the vasoreactivity of the radial graft without totally obviating at least angiographic spasm. This drug is easy to titrate, and well tolerated in association to beta-blockers in the routine perioperative management of the coronary patients. [less ▲]

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See detailUne innovation dans la chirurgie hellénistique: l'opération de la cataracte
Marganne, Marie-Hélène ULg

in Medizinhistorisches Journal (2001), 36(1), 23-33

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See detailA world monograph of the lichen genus Gyalectidium (Gomphillaceae)
Ferraro, Lidia Itati; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Botanical Journal of the Linnean Society (2001), 137

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See detailChanges in major intracellular osmolytes in L-929 cells following rapid and slow application of hyperosmotic media.
Libioulle, Cécile ULg; Corbesier, L.; Gilles, Raymond ULg

in Comparative Biochemistry & Physiology Part A : Molecular & Integrative Physiology (2001), 130(3), 461-70

Cultured L-929 cells respond to media-made hyperosmotic (600 mOsmol/kg H2O) by addition of NaCl, sorbitol or proline by adjusting successively their intracellular level in different osmolytes: Na+, K ... [more ▼]

Cultured L-929 cells respond to media-made hyperosmotic (600 mOsmol/kg H2O) by addition of NaCl, sorbitol or proline by adjusting successively their intracellular level in different osmolytes: Na+, K+, amino acids and sorbitol. In the NaCl medium, Na+ and K+ are first to increase. Their concentration is then down-regulated while they are replaced by less disrupting osmolytes: amino acids and sorbitol. The amino-acid level is also adjusted with respect to the increase in sorbitol which starts only after 24 h, depending on the induction of aldose reductase. A similar evolution in the amount of these osmolytes is observed, with different time scales and amplitudes, depending on whether the osmotic shocks are applied abruptly or slowly, in a more physiological way. The interplay between the osmolytes is also different depending on their availability in the external medium. Such complex evolutions indicate that a cascade of interacting signals must be considered to account for the overall regulation process. It can hardly be fitted into a model implicating a single primary signalling event (early increase in ions or decrease in cell volume) as usually postulated. Also, the volume up-regulation is not significantly different in the different conditions, showing that it is not primarily dependent on the adjustment of the intracellular osmolarity which is reached immediately upon cell shrinkage and is maintained all over, independently of the availability and changes in nature of the osmolytes. [less ▲]

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See detailProthèses péniennes : taille du pénis implanté et dimensions de la virilité
Kempeneers, Philippe ULg; Andrianne, Robert ULg; Mormont, Christian ULg et al

in Cahiers de Sexologie Clinique (2001), 27(149), 18-27

The implantation of a penile prosthesis frequently results in a reduction of the erectile length compared with natural erections. Some patients complain about this fact and their satisfaction at ... [more ▼]

The implantation of a penile prosthesis frequently results in a reduction of the erectile length compared with natural erections. Some patients complain about this fact and their satisfaction at prosthesis assisted sexuality is significantly diminished. Obviously, the degree of complaint is not proportional to the objective degree of penile reduction. For an objective reality to lead to complaints, subjective criteria of appreciation have to intervene. A survey questionnaire completed by 39 implanted patients and 30 partners shows that complaints about the size of the implanted penis are mostly related to a social representation of sexuality which associates the male erotic value to criteria of erectile length, spontaneity and “naturalness”. This representation also tends to be projected in the partner’s mind, independently of her actual attitudes and feelings. Therefore, the injurious impact of penile reduction on satisfaction at the prosthetic device seems to be inseparable from a global representation of prosthetic sexuality which is experienced as a “parodic”, “reduced” virility. The reduced size of the penis focuses feelings of vexation which cannot be reduced to simple functional considerations, it embodies the painful and complex image of a lost virility. From this point of view, psychosexological counselling would be indicated in order to help some couples to improve their adaptation to penile prosthesis. Moreover, an Attitude scale towards Penile Implant (API) derived from the survey questionnaire might enable the identification of risk-patients. [less ▲]

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See detailModified hormonal balance in rooting-recalcitrant rac mutant tobacco shoots
Faivre-Rampant, Odile; Kevers, Claire ULg; Dommes, Jacques ULg et al

in Plant Biosystems (2001), 135(1), 85-93

The rooting-recalcitrant rac tobacco mutant has been multiplied in vitro via outgrowth of axillary buds in parallel to the DS wild-type. The mutant shoots grew at a lower rate and did not root whatever ... [more ▼]

The rooting-recalcitrant rac tobacco mutant has been multiplied in vitro via outgrowth of axillary buds in parallel to the DS wild-type. The mutant shoots grew at a lower rate and did not root whatever the treatments, whereas the wild-type shoots rooted spontaneously during the culture cycle without auxin treatment. The mutant and wild-type shoots showed similar peroxidase variations along the culture cycle (21 days) but with higher levels of activity for the rac mutant: minimum peroxidase activity occurrey at day 14 in whole shoots of both tobacco genotypes, but already at day 7 in the basal parts of the stems (where roots appear) of the wild-type tobacco, while it was delayed in the mutant. Free and conjugated auxin and polyamine levels were also determined in whole shoots and basal parts of the stems. The rac mutant was characterised by higher auxin and polyamine contents. A peak of auxins and polyamines appeared at day 14 in the whole shoots whatever the tobacco genotype. This peak was delayed in the basal parts of the rac stems compared to the wild-type ones. The mutant shoots contained higher levels of benzyladenine and isopentenyladenosine at the end of the culture cycle, whereas zeatin riboside was more abundant in wild-type shoots. In response to increasing concentrations of indole-3-butyric acid (IBA) and 1-naphthaleneacetic acid (NAA), only the wild-type shoots responded by an increase in growth rate followed by inhibition at high concentrations. The rac shoot responses were very low or nonexistent. Peroxidase activity was also measured in E basal parts of tobacco stems grown in the presence of IBA. Results suggest growth inhibition related to auxin accumulation, possibly combined with elevated putrescine content. Second, rooting induction seems to take place in both tobacco genotypes; however, the process of root formation is blocked in the mutant. The lack of initiation and expression phases of rooting in relation to auxin content in the mutant is discussed. [less ▲]

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See detailAutour d'Henri Bles à Liège
Allart, Dominique ULg; Fraiture Pascale; Oger, Cécile ULg et al

in Feuillets de la Cathédrale de Liège (2001), 46-53

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See detailAb initio simulations of liquid semiconductors using the pseudopotential-density functional method
Chelikowsky, J. R.; Derby, J. J.; Godlevsky, V. V. et al

in Journal of Physics : Condensed Matter (2001), 13(41), 817-854854

One of the most difficult problems in condensed matter physics is describing the microscopic nature of the liquid state. Owing to the dynamical nature of the liquid state, it is not possible to discuss a ... [more ▼]

One of the most difficult problems in condensed matter physics is describing the microscopic nature of the liquid state. Owing to the dynamical nature of the liquid state, it is not possible to discuss a particular microscopic structure; only ensemble averages can be specified. Such averages can be performed via well crafted molecular dynamics simulations: the length of the simulation, the size of the ensemble and the nature of the interatomic forces must all be carefully analysed. Historically, a problematic issue in doing such simulations is that of how to describe the interatomic forces in the liquid state. This matter is especially challenging for the melt of semiconductors, such as silicon or gallium arsenide, where the chemical bond contains a strong covalent component. It is difficult to use pairwise interatomic potentials in such cases. Although many-body potentials can be utilized for simulations of these materials, one must map quantum phenomena such as hybridization onto classical interatomic potentials. This mapping is complex and difficult. In this review, we illustrate how one can avoid this problem by utilizing quantum forces to simulate liquids. Our focus is on the pseudopotential-density functional method. Within the pseudopotential method, only the valence electrons are explicitly treated and within the density functional theory, exchange and correlation terms are mapped onto an effective one-electron potential [less ▲]

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See detailPerspectives de vaccination anti-dermatophytique chez les carnivores domestiques
Descamps, F.; Brouta, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailQuelle biodiversite pour nos lisieres forestieres?
Branquart, E.; Doucet, Jean-Louis ULg; Liesse, D. et al

in Parcs & Réserves (2001), 56(1), 26-32

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See detailIatrogenic thyrotoxicosis. Causal circumstances, pathophysiology and principles of treatment. Review of the literature
Meurisse, Michel ULg; Preud'Homme, Laurence ULg; Lamberty, Geoffrey ULg et al

in Acta Chirurgica Belgica (2001), 101(6), 257-266

Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances, thyrotoxicosis is due to hyperthyroidism, a term reserved ... [more ▼]

Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances, thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis may also result from a variety of conditions other than thyroid hyperfunction. The present report focuses on the etiologies, pathophysiology and treatment of iatrogenic thyrotoxicosis. Iatrogenic thyrotoxicosis may be caused by 1) subacute thyroiditis (a result of lymphocytic infiltration, cellular injury, trauma or radiation) with release of preformed hormones into circulation, 2) excessive ingestion of thyroid hormones ("thyrotoxicosis factitia"), 3) iodine-induced hyperthyroidism (radiological contrast agents, topical antiseptics or other medications). Among these causes of iatrogenic thyrotoxicosis, that induced by the iodine overload and cytotoxicity associated with amiodarone represents a significant challenge. Successful management of amiodarone-induced thyrotoxicosis requires close cooperation between endocrinologists and endocrine Surgeons. Surgical treatment may have a leading yet often underestimated role in view of the potential life-threatening severity of this disease, whereas others kinds of iatrogenic thyrotoxicosis are usually treated conservatively. [less ▲]

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See detailThe effects of JL 13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia
Ellenbroek, Bart; Liégeois, Jean-François ULg; Bruhwyler, Jacques et al

in Journal of Pharmacology and Experimental Therapeutics (2001), 298

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See detailAperçu du régime alimentaire du Grand Cormoran (Phalacrocorax carbo) dans les eaux intérieures du Pas-de-Calais (France)
Libois, Roland ULg

in Aves (2001), 38(2), 49-59

The stomach contents of 40 great cormorants shot during "regulation" operations in the Pas-de-Calais have been analysed. Eight stomachs were empty and 426 fishes belonging to 15 species were recovered in ... [more ▼]

The stomach contents of 40 great cormorants shot during "regulation" operations in the Pas-de-Calais have been analysed. Eight stomachs were empty and 426 fishes belonging to 15 species were recovered in the others. The dominant prey is the roach. Other regular prey are the common bream and the perch. Other fish (Salmonids, pike, pikeperch, ruffe, rudd, lamprey) appear in less than 5 stomachs. Most of the prey are small sized fish, less than 12 cm (total length). The biomass of 80% of the preys is less than 20g. However, the role of the greater fish in the diet must be emphasized: those weighing more than 200g (1% in numbers) reprensent 20% of the ingested biomass. [less ▲]

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See detailSurface Modification of Polycarbonate and Poly(ethyleneterephthalate) Films and Membranes by Polyelectrolyte Deposition
Dauginet, Laurence; Duwez, Anne-Sophie ULg; Legras, Roger et al

in Langmuir (2001), 17

The surface modification by chemical or physical adsorption of a polyelectrolyte (polyallylamine, PAH) was established using hydrolyzed polycarbonate (PC) and poly(ethylene terephthalate) (PET) thick and ... [more ▼]

The surface modification by chemical or physical adsorption of a polyelectrolyte (polyallylamine, PAH) was established using hydrolyzed polycarbonate (PC) and poly(ethylene terephthalate) (PET) thick and thin films. Contact angle data indicated changes in the hydrophilicity of PET film surfaces in terms of the chemical treatment. XPS analysis showed that the immobilization of PAH on PET and PC films was effective and that the amount of chemically or/and physically bounded PAH depends on the pH of the electrolyte solution used for the adsorption. Similar treatments have been successfully applied to polymeric track-etched membranes. These modified membranes have been used as templates for the synthesis of polypyrrole (PPy) nanotubules. FE-SEM analysis showed that much thicker PPy tubules were obtained in modified membranes than in virgin ones. This indicates that the surface chemistry of the pore walls plays an important role in the morphology of the nanostructures synthesized within the pores [less ▲]

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See detailCrystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38.
Wouters, J.; Georis, J.; Engher, D. et al

in Acta Crystallographica Section D-Biological Crystallography (2001), 57(Pt 12), 1813-9

Family 11 endo-beta-1,4-xylanases degrade xylan, the main constituent of plant hemicelluloses, and have many potential uses in biotechnology. The structure of Xyl1, a family 11 endo-xylanase from ... [more ▼]

Family 11 endo-beta-1,4-xylanases degrade xylan, the main constituent of plant hemicelluloses, and have many potential uses in biotechnology. The structure of Xyl1, a family 11 endo-xylanase from Streptomyces sp. S38, has been solved. The protein crystallized from ammonium sulfate in the trigonal space group P321, with unit-cell parameters a = b = 71.49, c = 130.30 A, gamma = 120.0 degrees. The structure was solved at 2.0 A by X-ray crystallography using the molecular-replacement method and refined to a final R factor of 18.5% (R(free) = 26.9%). Xyl1 has the overall fold characteristic of family 11 xylanases, with two highly twisted beta-sheets defining a long cleft containing the two catalytic residues Glu87 and Glu177. [less ▲]

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See detailComment je traite une ascite
Gielen, S.; Delwaide, Jean ULg; Detry, Olivier ULg et al

in Revue Médicale de Liège (2001), 56(12), 809-815

Ascites is the most common of the major complications of cirrhosis. The initial evaluation of a patient with ascites should include a history, physical evaluation and some investigations. Treatment should ... [more ▼]

Ascites is the most common of the major complications of cirrhosis. The initial evaluation of a patient with ascites should include a history, physical evaluation and some investigations. Treatment should consist of treating the underlying liver disease, sodium restricted diet (2 g of Na+/day) and diuretics. This regimen is effective in 90 % of patients. The treatment options for the diuretic-resistant patients include serial therapeutic paracentesis, peritoneovenous shunting, TIPSand liver transplantation. The treatment and prophylaxis of spontaneous bacterial peritonitis which is a frequent and severe complication in cirrhotic patients with ascites is also important. The differential diagnosis with secondary bacterial peritonitisis is essential because the latter usually does not resolve unless patients are surgically treated. [less ▲]

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See detailBelgique: l'euthanasie pourrait ne pas constituer une infraction
Mormont, Christian ULg

in Courrier de l'éthique médicale (2001), 1(2), 33-34

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See detailIsokinetic evaluation of hip strength muscle groups in unilateral lower limb amputees
Croisier, Jean-Louis ULg; Maertens De Noordhout, Benoît ULg; Maquet, Didier ULg et al

in Isokinetics & Exercise Science (2001), 9(4), 163-169

The objectives of the study were to measure the isokinetic strength of the hip flexor-extensor and adductor-abductor muscle groups in unilateral lower limb amputees and to evaluate abnormalities in order ... [more ▼]

The objectives of the study were to measure the isokinetic strength of the hip flexor-extensor and adductor-abductor muscle groups in unilateral lower limb amputees and to evaluate abnormalities in order to improve the usual rehabilitation programs. Thirty-three patients with unilateral lower limb amputation were included in this study; they served as their own controls, the amputated side being compared to the intact side. Using an isokinetic device, the relative peak torques (N.m by body weight), bilateral asymmetries and agonist/antagonist torque ratios were calculated for the hip flexor, extensor, adductor and abductor muscle groups. A significant reduction of mean concentric relative peak torque measured on the amputated limbs was generally observed when compared to the intact contralateral limb (p < 0.05). The mean percentage of relative peak torque decrease was greater for the extensors than for the flexors (33 +/- 20% and 22 +/- 23%, respectively, at 30degrees/s angular velocity), and for the abductors than for the adductors (23 +/- 22% and 11 +/- 19%, respectively, at 30degrees/s angular velocity). Furthermore, the flexor/extensor torque ratio was significantly increased for the amputated limb (for instance, 1.25 +/- 0.33 versus 1.09 +/- 0.25 for the intact limb at 30degrees/s). The reduction of the abductor/adductor ratio of the operated limb reached the level of statistical significance at 60degrees/s only (1.25 +/- 0.46 versus 1.07 +/- 0.36 for the intact limb). In conclusion, isokinetic testing revealed a significant reduction of the hip stabilizing muscle strength as a consequence of lower limb amputation. The more marked decrease of the strength of the abductor and extensor muscle groups, resulting in imbalances of the agonist/antagonist strength ratios should be taken into account to adapt the conventional rehabilitation programs. [less ▲]

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See detailPropositions relatives à l'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 79-84

Comme pour le texte 'L'avenir de l'enseignement' qui est publié dans ces Cahiers, il s'agit d'un texte qui date d'une dizaine d'années. Ces propositions ont été formulées peu de temps après la ... [more ▼]

Comme pour le texte 'L'avenir de l'enseignement' qui est publié dans ces Cahiers, il s'agit d'un texte qui date d'une dizaine d'années. Ces propositions ont été formulées peu de temps après la communautarisation complète de l'enseignement. A présent que 'nous sommes maîtres chez nous', qu'en est-il ? Quel chemin avons-nous parcouru ? S'agissait-il de prémonitions ? De rêves et d'utopies ? Chacun peut s'en faire une idée. Chacun peut aussi apprécier, sur la base d'un texte, ce qui se disait alors et ce que Gilbert de Landsheere envisageait comme souhaitable. [less ▲]

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See detailHuman Fdc Express Prpc in Vivo and in Vitro
Thielen, Caroline ULg; Antoine, Nadine ULg; Mélot, France ULg et al

in Developmental Immunology (2001), 8(3-4), 259-66

Prion diseases are fatal neurodegenerative disorders caused by accumulation of abnormal prion protein (protease-resistant prion, PrPres). PrPres accumulation is also detected in lymphoid organs after ... [more ▼]

Prion diseases are fatal neurodegenerative disorders caused by accumulation of abnormal prion protein (protease-resistant prion, PrPres). PrPres accumulation is also detected in lymphoid organs after peripheral infection. Several studies suggest that follicular dendritic cells (FDC) could be the site of PrPres retention and amplification. Here we show that human follicular dendritic cells can express normal cellular prion protein (PrPc) both in situ and in vitro. When tonsillar cryosections were treated with anti-PrP antibody, the label was found on some very delicate cell extensions inside the lymphoid follicles, especially in the germinal centres. These extensions react with DRC1 antibody, used frequently to label FDC. Other structures labelled with anti-PrP antibody were the keratinocytes. To confirm the ability of FDC to synthesise PrPc, we isolated FDC by a non-enzymatic procedure and cultured them. By cytochemistry and flow cytometry it was clearly shown that FDC do produce PrPc. [less ▲]

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See detailGenesis of clone size heterogeneity in megakaryocytic and other hemopoietic colonies: the stochastic model revisited
Paulus, Jean-Michel ULg; Levin, Jack; Debili, Najet et al

in International Society for Experimental Hematology (2001), 29(nd), 1256-69

OBJECTIVE: We previously showed that the distributions of the numbers of doublings (NbD) undergone by individual megakaryocyte progenitors before commitment to polyploidization are markedly skewed and can ... [more ▼]

OBJECTIVE: We previously showed that the distributions of the numbers of doublings (NbD) undergone by individual megakaryocyte progenitors before commitment to polyploidization are markedly skewed and can consistently be fitted to straight lines when plotted on semilogarithmic coordinates. The slope of such lines, which yields the probability of polyploidization per doubling, is made less steep by stimulators of megakaryocyte colony formation and is less steep in mixed erythroid-megakaryocyte than in pure megakaryocyte colonies. Therefore, megakaryocytopoiesis provides a unique model for the study of clonal heterogeneity in a hemopoietic lineage, which is the subject of this review. DATA SOURCES: Articles relevant to the interpretation of these data were selected from the authors' and public databases. DATA SYNTHESIS: Exponential NbD distributions were first explained by postulating that following the assembly of thrombopoiesis-specific regulators, megakaryocyte progenitors require only a single random event to arrest proliferation and commit to polyploidization. However, this stochastic model was refuted by data indicating that intrinsic properties of individual progenitors affect the NbD they achieve. We suggest that the unequal repartition of critical compounds (including receptors, signaling molecules, and gene regulators) inherent in the stem cell-progenitor transition causes a heritable heterogeneity in megakaryocyte progenitor responsiveness to polyploidization inducers. This model would be compatible with 1) the evidence for intraclonal synchronization in megakaryocyte and other hemopoietic clones generated by committed progenitors; 2) the low probability of polyploidization of the relatively insensitive bipotent megakaryocyte progenitors; and 3) the thesis that stimulators act in part by recruiting megakaryocyte progenitor cells endowed with lesser responsiveness to polyploidization inducers and higher proliferative potential. CONCLUSION: The responsiveness of individual megakaryocyte progenitors to polyploidization inducers may be a major determinant of the exponential shape of NbD distributions. [less ▲]

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See detailErosion of Deccan Traps determined by river geochemistry: impact on the global climate and the Sr-87/Sr-86 ratio of seawater
Dessert, C.; Dupre, B.; François, Louis ULg et al

in Earth And Planetary Science Letters (2001), 188(3-4), 459-474

The impact of the Deccan Traps on chemical weathering and atmospheric CO2 consumption on Earth is evaluated based on the study of major elements, strontium and Sr-87/Sr-86 isotopic ratios of the main ... [more ▼]

The impact of the Deccan Traps on chemical weathering and atmospheric CO2 consumption on Earth is evaluated based on the study of major elements, strontium and Sr-87/Sr-86 isotopic ratios of the main rivers flowing through the traps, using a numerical model which describes the coupled evolution of the chemical cycles of carbon. alkalinity and strontium and allows one to compute the variations in atmospheric pCO(2), mean global temperature and the Sr-87/Sr-86 isotopic ratio of seawater, in response to Deccan trap emplacement. The results suggest that the rate of chemical weathering of Deccan Traps (21-63 t/km(2)/yr) and associated atmospheric CO consumption (0.58-2.54 x 10(6) mol C/km(2)/yr) are relatively high compared to those linked to other basaltic regions. Our results on the Deccan and available data from other basaltic regions show that runoff and temperature are the two main parameters which control the rate of CO2 consumption during weathering of basalts, according to the relationship: f = R-f x C(0)exp[-Ea/R(1/T-1/298)] where f is the specific CO2 consumption rate (mol/km(2)/yr), R-f is runoff (mm/yr), C-0 is a constant (= 1764 mu mol/l), Ea represents an apparent activation energy for basalt weathering (with a value of 42.3 kJ/mol determined in the present study), R is the gas constant and T is the absolute temperature (K-o). Modelling results show that emplacement and weathering of Deccan Traps basalts played an important role in the geochemical cycles of carbon and strontium. In particular, the traps led to a change in weathering rate of both carbonates and silicates, in carbonate deposition on seafloor, in Sr isotopic composition of the riverine flux and hence a change in marine Sr isotopic composition. As a result, Deccan Traps emplacement was responsible for a strong increase of atmospheric pCO(2) by 1050 ppmv followed by a new steady-state pCO(2) lower than that in pre-Deccan times by 57 ppmv, implying that pre-industrial atmospheric pCO(2) would have been 20% higher in the absence of Deccan basalts. pCO(2) evolution was accompanied by a rapid warming of 4 degreesC, followed after 1 Myr by a global cooling of 0.55 degreesC. During the warming phase, continental silicate weathering is increased globally. Since weathering of continental silicate rocks provides radiogenic Sr to the ocean, the model predicts a peak in the Sr-87/Sr-86 ratio of seawater following the Deccan Traps emplacement. The amplitude and duration of this spike in the Sr isotopic signal are comparable to those observed at the Cretaceous-Tertiary boundary. The results of this study demonstrate the important control exerted by the emplacement and weathering of large basaltic provinces on the geochemical and climatic changes on Earth. (C) 2001 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailImage du mois. Abces cerebral et toxoplasmose.
Omazic, A. F.; Welter, P.; Piette, Jacques ULg et al

in Revue Médicale de Liège (2001), 56(8), 541-2

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See detailBone resorption in post-menopausal women with normal and low BMD assessed with biochemical markers specific for telopeptide derived degradation products of collagen type I
Reginster, Jean-Yves ULg; Henrotin, Yves ULg; Christiansen, C. et al

in Calcified Tissue International (2001), 69(3), 130-137

Biochemical markers of bone resorption can be used clinically to predict the risk of osteoporosis-related fractures (prognostic tool) and to assess the response of an osteoporotic patient to an ... [more ▼]

Biochemical markers of bone resorption can be used clinically to predict the risk of osteoporosis-related fractures (prognostic tool) and to assess the response of an osteoporotic patient to an antiresorptive therapy (monitoring tool). Our aim was to assess the ability of four currently marketed biochemical markers of bone resorption, based on the measurement of degradation products from collage type I telopeptides to monitor the elevated resorption associated with menopause. Women (846) were stratified for menopause, age, and bone mineral density and the following markers were measured: urinary cross-linked N-telopeptides of type I collagen (NTx), the levels of breakdown products of type I collagen C-telopeptides in serum (S-CTx), and in urine, by ELISA (U-CTx-E), and RIA (U-CTx-R). Furthermore, the ratio (a/b) between the aL form of CTx measured in the CTx RIA and the bL form measured in the ELISA was calculated. The mean difference was calculated for each marker in women with osteopenia (Op) or osteoporosis (PMO) (WHO definition) compared with healthy premenopausal (Pre) women and postmenopausal (N Post) women with normal bone mass. Serum CTx showed the highest elevation in post- compared with premenopausal women. All marker values were significantly higher in Op and PMO subjects compared with both Pre and to N Post women. Compared with premenopausal values, the largest elevation in both Op and PMO women was observed for serum CTx. Compared with N Post, urine NTx showed the highest increase in OP subjects. The a/b CTx ratio was elevated in post- compared with Pre women, but there was no difference in the ratio among N Post, Op, or PMO women. In conclusion, postmenopausal women showed elevated turnover with all bone resorption markers, but with substantial individual variation in resorption levels. Furthermore, the turnover process in postmenopausal women appears to be quantitatively different from the premenopausal stage, apparent as altered a/b CTx ratios. [less ▲]

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See detailDistinct carbohydrate recognition domains of an invertebrate defense molecule recognize Gram-negative and Gram-positive bacteria.
Bilej, M.; De Baetselier, P.; Van Dijck, E. et al

in Journal of Biological Chemistry (2001), 276(49), 45840-7

Coelomic fluid of Eisenia foetida earthworms (Oligochaeta, Annelida) contains a 42-kDa defense molecule named CCF for coelomic cytolytic factor. By binding microbial antigens, namely the O-antigen of ... [more ▼]

Coelomic fluid of Eisenia foetida earthworms (Oligochaeta, Annelida) contains a 42-kDa defense molecule named CCF for coelomic cytolytic factor. By binding microbial antigens, namely the O-antigen of lipopolysaccharide (LPS), beta-1,3-glucans, or N,N'-diacetylchitobiose present, respectively, on Gram-negative bacteria or yeast cell walls, CCF triggers the prophenoloxidase activating pathway. We report that CCF recognizes lysozyme-predigested Gram-positive bacteria or the peptidoglycan constituent muramyl dipeptide as well as muramic acid. To identify the pattern recognition domains of CCF, deletion mutants were tested for their ability to reconstitute the prophenoloxidase cascade in E. foetida coelomic fluid depleted of endogenous CCF in the presence of LPS, beta-1,3-glucans, N,N'-diacetylchitobiose, and muramic acid. In addition, affinity chromatography of CCF peptides was performed on immobilized beta-1,3-glucans or N,N'-diacetylchitobiose. We found that the broad specificity of CCF for pathogen-associated molecular patterns results from the presence of two distinct pattern recognition domains. One domain, which shows homology with the polysaccharide and glucanase motifs of beta-1,3-glucanases and invertebrate defense molecules located in the central part of the CCF polypeptide chain, interacts with LPS and beta-1,3-glucans. The C-terminal tryptophan-rich domain mediates interactions of CCF with N,N'-diacetylchitobiose and muramic acid. These data provide evidence for the presence of spatially distinct carbohydrate recognition domains within this invertebrate defense molecule. [less ▲]

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See detailImpaired emotional facial expression in alcoholism compared with obsessive compulsive disorder and normal controls
Kornreich, C; Blairy, Sylvie ULg; Philippot, P et al

in Psychiatry Research (2001), 102

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See detailKinetics of light emission and oxygen consumption by bioluminescent bacteria.
Bourgeois, J. J.; Sluse, Francis ULg; Baguet, F. et al

in Journal of Bioenergetics & Biomembranes (2001), 33

Oxygen plays a key role in bacterial bioluminescence. The simultaneous and continuous kinetics of oxygen consumption and light emission during a complete exhaustion of the exogenous oxygen present in a ... [more ▼]

Oxygen plays a key role in bacterial bioluminescence. The simultaneous and continuous kinetics of oxygen consumption and light emission during a complete exhaustion of the exogenous oxygen present in a closed system has been investigated. The kinetics are performed with Vibrio fischeri, V. harveyi, and Photobacterium phosphoreum incubated on respiratory substrates chosen for their different reducing power. The general patterns of the luminescence time courses are different among species but not among substrates. During steady-state conditions, substrates, which are less reduced than glycerol, have, paradoxally, a better luminescence efficiency. Oxygen consumption by luciferase has been evaluated to be approximately 17% of the total respiration. Luciferase is a regulatory enzyme presenting a positive cooperative effect with oxygen and its affinity for this final electron acceptor is about 4-5 times higher than the one of cytochrome oxidase. The apparent Michaelis constant for luciferase has been evaluated to be in the range of 20 to 65 nM O2. When O2 concentrations are as low as 10 nM, luminescence can still be detected; this means that above this concentration, strict anaerobiosis does not exist. By n-butyl malonate titration, it was clearly shown that electrons enter the luciferase pathway only when the cytochrome pathway is saturated. It is suggested that, in bioluminescent bacteria, luciferase acts as a free-energy dissipating valve when anabolic processes (biomass production) are impaired. [less ▲]

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See detailRevenant & exorcisme à Liège. Quête de reliques en Sardaigne (1634-1652)
George, Philippe ULg

in Bulletin de la Commission Royale d'Histoire (2001), CLXVII

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See detailL'autonomie fiscale des communautés et des régions après les accords du Lambermont
Bourgeois, Marc ULg

in Actualités du Droit (2001)

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See detailPalaeogeographic and palaeoenvironmental characteristics of major marine incursions in northwestern Europe during the Westphalian C (Bolsovian).
Dusar, M; Paproth, E; Streel, Maurice ULg et al

in Geologica Belgica (2001), (2000)3(3-4), 331-347

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See detailModelling and design of an electrostatically levitated disc for inertial sensing applications
Kraft, Michael ULg; Farooqui, Mateen M.; Evans, Alan G. R.

in Journal of Micromechanics and Microengineering (2001), 11(4), 423--427

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See detailNovel plasma extraction procedure and development of a specific enzyme immunoassay of oxytocin: application to biological and clinical investigations of small-cell carcinoma of the lung
Pequeux, Christel ULg; Hendrick, Jean-Claude; Hagelstein, Marie-Thérèse ULg et al

in Scandinavian Journal of Clinical & Laboratory Investigation (2001), 61(5), 407-415

Paraneoplastic secretion of the lactation-inducing hormone oxytocin (OT) has been reported in about 30% of cases of small cell carcinoma of the lung (SCCL). In order to investigate the role of OT in the ... [more ▼]

Paraneoplastic secretion of the lactation-inducing hormone oxytocin (OT) has been reported in about 30% of cases of small cell carcinoma of the lung (SCCL). In order to investigate the role of OT in the biology of SCCL tumours, a specific enzyme-immunoassay(EIA) for OT, which can be applied to both human plasma <br />and culturemedium, has been developed. OT EIA is performed on 96-well microtiter plates coated with a rabbit polyclonal antibody (Ab) anti-OT (O4). This antibody does not exhibit any significant cross-reactivity either with vasopressin (VP) or with vasotocin (VT). The immunological reaction involving Ab anti-OT is a competition between the tracer (biotinylatedOT) and syntheticOT (standard curve) or OT present in biological samples. In order to limit interference induced by plasma proteins, plasma samples are titrated by a one-step centrifugation on centricon YM-3 (cut-oOE 3000 Da). After plasma filtration, 90.7 ± 5.1 (SD) % (n = 22) immunoreactive ( IR) OT is recovered. The sensitivity of OT EIA is 1 pmol/L, while intra- and inter-assay coefficients of variation (CV) are around 3.41% and 2.84%, respectively. In healthy volunteers, plasma IR OT is 7.28 ± 4.49 (SD) pmol/L (n = 32) with no gender diOEerence. As shown by the data both from plasma of SCCL patients and from supernatants and cell contents of SCCL cell lines, this EIA procedure offers a novel, reproducible, specific and sensitive method for the measurement of IR OT. [less ▲]

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See detailComparison between the GIRBAS Scale and the Acoustic and Aerodynamic Measures Provided by EVA for the Assessment of Dysphonia following Unilateral Vocal Fold Paralysis.
Morsomme, Dominique ULg; Jamart, Jacques; Wery, Carine et al

in Folia Phoniatrica et Logopaedica (2001), 53(6), 317-25

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures ... [more ▼]

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures. The objective measures were obtained using a voice analysis software (Evaluation Vocale Assistee), whereas the perceptual measures were established with the GIRBAS Scale (grade, instability, roughness, breathiness, asthenia, and strain). All measurements were performed on 40 voice samples: 28 dysphonic subjects with unilateral laryngeal paralysis, and 12 control subjects. The intra- and inter-judge agreements were fairly good, at least for control subjects. The six GIRBAS measures obtained from the pathological voices were higher than those from the control voices (p < 0.001) and the correlation between both groups was good. Grade, breathiness and asthenia correlated with the objective parameters that express the aperiodicity of the phonatory signal (p < 0.01), namely, the coefficient of variability of the fundamental frequency, the coefficient of variability of intensity, and jitter. Our findings suggest that the perceptual reality of laryngeal paralysis-induced dysphonia depends more on grade, breathiness and asthenia than it does on roughness or instability. [less ▲]

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See detailSémiologie cardiaque dans l’espèce équine. 1- L’anamnèse et l’examen clinique.
Amory, Hélène ULg

in Pratique Vétérinaire Equine (2001), 33

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See detailLes mélèzes
Rondeux, Jacques ULg; Pauwels, D.

in Fiche technique (2001)

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See detailSmall Town China. Goverance, Economy, Environment and Lifestyle in Three Zhen
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2001), Vol. XVIII

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See detailCharge critique et longueur de flambement des éléments à inertie variable et aux conditions d'extrémité élastiques
Latteur, Pierre ULg

in revue scientifique des Instituts supérieurs industriels francophones de Belgique (2001), 15

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See detailCompte rendu de Frédéric Barbier, Histoire du livre
Durand, Pascal ULg

in Bulletin des Bibliothèques de France (2001), 46/4

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See detailTraçabilité dans la filière viande. I. La traçabilité administrative.
Evrard, V.; China, B.; Noirfalise, R. et al

in Annales de Médecine Vétérinaire (2001), 145

Le secteur de la viande a été secoué ces dernières années par quelques scandales, tels ceux des hormones et de la dioxine, avec pour conséquences une perte de confiance de la part du consommateur et une ... [more ▼]

Le secteur de la viande a été secoué ces dernières années par quelques scandales, tels ceux des hormones et de la dioxine, avec pour conséquences une perte de confiance de la part du consommateur et une perturbation du marché de la viande. Pour redresser l’image des produits carnés belges, il est important de pouvoir en déterminer et en garantir l’origine. En Belgique, il existe divers systèmes de traçabilité administrative dont le principal est le système SANITEL qui comprend un système automatisé de traitement de données relatives à l’identification et l’enregistrement des animaux. Au-delà de l’aspect légal et réglementaire, différentes initiatives, visant une amélioration de la qualité, fleurissent : "les labels". Ceux-ci intègrent fréquemment la traçabilité dans leur cahier des charges. La traçabilité administrative n’est pas infaillible, la perte de documents et les fraudes peuvent ternir l’image de celle-ci. C’est pourquoi le système documentaire a été associé aux empreintes génétiques des animaux. 5 [less ▲]

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See detailMicrowave Corneosurfametry and the Short-Duration Dansyl Chloride Extraction Test for Rating Concentrated Irritant Surfactants
Goffin, Véronique ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2001), 202(1), 46-8

BACKGROUND: There are ethical concerns to conduct in vivo tests in the animal and human to provide evidence that cosmetics and other topical products are safe. OBJECTIVE: To compare two methods, namely ... [more ▼]

BACKGROUND: There are ethical concerns to conduct in vivo tests in the animal and human to provide evidence that cosmetics and other topical products are safe. OBJECTIVE: To compare two methods, namely the short-duration dansyl chloride extraction test and the microwave corneosurfametry bioassay, to test the irritation potential of concentrated surfactant systems. METHODS: Five surfactants and water were tested using the in vivo test and the bioassay. RESULTS: A significant linear correlation was found between data yielded by the two procedures. CONCLUSION: The short-duration dansyl chloride extraction test and the microwave corneosurfametry bioassay provide similar information. The latter has the advantage of being safe. [less ▲]

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See detailSens de la cohérence, colère et trouble obsessionnel-compulsif
Lambert, Stéphanie; Etienne, Anne-Marie ULg; Fontaine, Ovide ULg

in Revue Francophone de Clinique Comportementale et Cognitive (2001), 6(4), 5-16

This study assesses the relationship between the Sense of Coherence (SoC) of Antonovsky, anger and the obsessive-compulsive disorder. The sample is composed of 42 subjects divided in two groups, 21 ... [more ▼]

This study assesses the relationship between the Sense of Coherence (SoC) of Antonovsky, anger and the obsessive-compulsive disorder. The sample is composed of 42 subjects divided in two groups, 21 subjects suffering of obsessive-compulsive disorder and 21 subjects matched controls. They completed a demographic questionnaire, the list of obsessions and compulsions of Goodman & al.(1989), translation Mollard, Cottraux & Bouvard (1989), the Visual Analogues Scales, the Orientation Life Questionnaire of Antonovsky (1987), the State-Trait Anger Expression Inventory of Spielberger (STAXI), the State-Trait Anxiety Inventory of Spielberger (STAI), and the Beck Depression Inventory (BDI). The results show higher scores of anxiety and depression in obsessive-compulsive patients than in controls subjects. According to the results obtained with the Anger Inventory, the obsessive-compulsive subjects show higher scores of state-anger, of anger-expression and higher scores of anger-control. The results of the Sense of Coherence scale reveal a lower SoC in TOC group than in control group. The SoC is also negatively associated with depression and anxiety in both groups. The SoC is negatively associated with the control of anger in the TOC group and with the suppression of anger in the control group. The theorical and clinical implications of these results are discussed. [less ▲]

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See detailSecondary fabrics revealed by remanence anisotropy: methodological study and examples from plutonic rocks
Trindade, Ricardo I.F.; Bouchez, Jean-Luc; Bolle, Olivier ULg et al

in Geophysical Journal International (2001), 147(2), 310-318

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See detailLiquid distribution images on structured packing by X-ray computed tomography
Marchot, Pierre ULg; Toye, Dominique ULg; Pelsser, A. M. et al

in AIChE Journal (2001), 47(6), 1471-1476

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See detailExtended analysis of the spectrum of triply-ionozed Ytterbium (Yb IV) and transition probabilities
Wyart, J.-F.; Tchang-Brillet, W. U. L.; Spector, N. et al

in Physica Scripta (2001), 63

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See detailBelgian normative data of the temperament and character inventory
Hansenne, Michel ULg; Le Bon, O.; Gauthier, Audrey ULg et al

in European Journal of Psychological Assessment (2001), 17(1), 56-62

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 ... [more ▼]

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 representative French-speaking subjects from Belgium are presented and the psychometric properties are discussed. Mean scores of temperament dimensions were appreciably different from those published by Cloninger. In our sample, novelty seeking and self-transcendence scores were lower and harm avoidance scores were higher compared to US norms. The other dimensions were almost identical. The factorial analysis showed that the hypothesized factor structure of temperament and character dimensions was almost confirmed. The present study also confirmed that the TCI scales were weakly related among themselves. The relationships were consistent with those reported by previous reports. Gender differences were also found for different dimensions. [less ▲]

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See detailLa sémiologie selon L.J. Prieto
Badir, Sémir ULg

in Linx (2001), 44

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See detailShort-term variations of the partial pressure of CO2 in surface waters of the Galician upwelling system
Borges, Alberto ULg; Frankignoulle, Michel

in Progress in Oceanography (2001), 50(2-4), 283-302

The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are ... [more ▼]

The partial pressure of CO2 (pCO2) and dissolved oxygen saturation level (%O2) were monitored continuously during a cruise in August 1998, which sampled surface waters off the Galician coast. Data are presented from two Lagrangian experiments carried out in an upwelling on the continental shelf and in the core of an offshore filament. The data show that daily variations in surface pCO2 and oxygen (%O2) were controlled by the diurnal cycle of primary production/respiration, temperature variations and air–sea exchange. Data obtained during various cross-shelf and cross-filament transects are also discussed and give an insight into the processes controlling large scale variations of pCO2 and %O2 in the Galician upwelling system. These data suggest that upwelling filaments are an important feature of the inorganic carbon cycle of upwelling systems. However more field data in the various eastern boundary current systems worldwide are needed. [less ▲]

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See detailSexual compatibility between two heterochronic morphs in the Alpine newt, Triturus alpestris
Denoël, Mathieu ULg; Poncin, Pascal ULg; Ruwet, Jean-Claude

in Animal Behaviour (2001), 62(3), 559-566

Paedomorphosis, in which individuals retain ancestral characteristics in the adult stage, is widespread in newts and salamanders and is suspected to play an important role in evolution. In some species ... [more ▼]

Paedomorphosis, in which individuals retain ancestral characteristics in the adult stage, is widespread in newts and salamanders and is suspected to play an important role in evolution. In some species, paedomorphosis is facultative with some individuals forgoing metamorphosis. Optimality models have been proposed to explain the maintenance of this polymorphism, but require the integration of reproductive patterns into the models. We investigated the frequencies of inbreeding and outbreeding in two syntopic heterochronic morphs of the Alpine newt. The two morphs are sexually compatible: encounters between and within morphs were equally successful in terms of spermatophore transfer. Behavioural observations were in agreement with the sexual compatibility observed. Nevertheless, paedomorphic males displayed to females less frequently than metamorphic males. The two morphs differ largely on the basis of sexual secondary characteristics, but the majority of these traits did not affect mating success. Because of the large flow of genes between the two heterochronic morphs and because of the absence of spatial and temporal isolation, these results do not support sympatric speciation models, but are in favour of the maintenance of polymorphism in natural populations. (C) 2001 The Association for the Study of Animal Behaviour. [less ▲]

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See detailAn equivalence test for comparing DNA sequences.
Thijs, H.; Van Steen, Kristel ULg; Molenberghs, G. et al

in American Journal of Human Genetics (2001), 69(4), 1576

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See detailA propos du remplage de la verrière d'Esther.
Morard, Thomas ULg

in Arte Cristiana (2001), 89(802), 23-30

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See detailLes troubles des fonctions exécutives dans la maladie d'Alzheimer
Collette, Fabienne ULg; Van der Linden, Martial ULg

in Alzheimer Actualités (2001), (155), 6-9

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See detailModification génétique de la levure Yarrowia lipolytica pour maîtriser la β-oxydation
Waché, Y.; Aguedo, Mario ULg; LeDall, M.-T. et al

in Journal de la Société de Biologie (2001), 195(4), 459-459

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car ... [more ▼]

Les biotechnologies font régulièrement appel à la β-oxydation pour produire des composés à haute valeur ajoutée ou dépolluer des effluents industriels. Cette voie métabolique est difficile à maîtriser car elle implique un nombre réduit d'enzymes pour une voie très longue. En particulier, la production d'intermédiaires réactionnels est délicate car les enzymes de la voie de reconsommation sont souvent les mêmes que celles impliquées dans la production. Ainsi, la production de γ-décalactone à partir de ricinoléate de méthyle chez Y. lipolytica implique la β-oxydation (Endrizzi et al., 1996). Cette levure est un bon modèle pour étudier le métabolisme des acides gras car elle possède cinq acyl-CoA oxydases (Aox) catalysant la première étape de la β-oxydation (Wang et al., 1999). L'effet d'une invalidation des gènes codant pour les Aox a été étudié sur la production de γ-décalactones. En fonction des Aox présentes dans les souches, différentes lactones sont produites et leur reconsommation peut être nettement ralentie. Cette étude montre qu'on peut maîtriser la β-oxydation en modifiant le matériel génétique des souches et qu'on peut ainsi améliorer les productions existantes mais aussi produire de nouvelles molécules d'intérêt. [less ▲]

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