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See detailLe traitement oncologique : polémique ou consensus ?
Coucke, Philippe ULg; MARTY

in Médecine et Hygiène (1995), 53(2076), 1371-1377

Les avis en oncologie sont souvent divergents. Ils illustrent un manque de «standard» thérapeutique bien établi. Cette revue a pour but de définir certaines de ces divergences fortement colorées par la ... [more ▼]

Les avis en oncologie sont souvent divergents. Ils illustrent un manque de «standard» thérapeutique bien établi. Cette revue a pour but de définir certaines de ces divergences fortement colorées par la spécialisation du médecin consulté. Ces divergences cesseront d'exister à condition de conduire des essais randomisés. Le praticien généraliste a un rôle prépondérant à jouer dans la motivation des malades afin qu'ils acceptent l'idée de ce genre d'étude. [less ▲]

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See detailGeographical research in Belgium : remote sensing and photo-interpretation
Donnay, Jean-Paul ULg; Wilmet, Jules

in Bulletin de la Société Belge d'Etudes Géographiques (1995), 2

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See detailManagement of high turnover osteoporosis with calcitonin
Reginster, Jean-Yves ULg

in Osteoporosis Digest (1995), 3

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See detailRespiratory adjustments in unacclimatised horses exercised under hot, humid conditions
Art, Tatiana ULg; Lekeux, Pierre ULg

in Equine Veterinary Journal. Supplement (1995), 18

The purpose of this study was to investigate the effect of a hot and humid environment on the pattern of breathing and the gas exchange in heavily exercising horses. Five healthy fit Standardbred horses ... [more ▼]

The purpose of this study was to investigate the effect of a hot and humid environment on the pattern of breathing and the gas exchange in heavily exercising horses. Five healthy fit Standardbred horses were investigated twice at 8 day intervals, once in temperate conditions (TC) (ambient temperature: 15°C; relative humidity: 55%) and once in hot and humid conditions (HHC) (ambient temperature: 30°C; relative humidity: 75%). The standardised treadmill exercise test consisted of 8 min warm-up and 8 min exercise (1 min at 1.7, 4, 7, 8, 9 and 10 m/s and 2 min at 4 m/s with a 6% slope). Running in HHC induced a significant decrease in peak expired minute volume (VE), oxygen uptake (VO2), VCO2 and oxygen pulse, while RQ remained unchanged and PACO2 increased. The changes in skin temperature (ST), i.e. the difference between ST at rest and at 10 m/s, was dramatically higher in HHC. The test induced changes, i.e. the differences between the values before and after the test, in cortisol, (beta-endorphins and plasma lactate (LA) values after the test were significantly higher. This study showed that performing a strenuous exercise in hot, humid conditions in unacclimatised horses induced a reduction of the aerobic capacity, i.e. decrease of the V02 and increase of LA production. A relative hypoventilation could be partly responsible for this observation, but all the steps of the oxygen transport from the pulmonary ventilation to the muscle metabolism could also potentially be impaired in such conditions [less ▲]

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See detailLa recherche scientifique et l'invention d'une société solidaire
de Landsheere, Gilbert ULg

in Bulletin de l'Association de la Noblesse du Royaume de Belgique (1995), (206), 22-28

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See detailBone mineral density of the spine and the hip measured with dual energy X-ray absorptiometry: normal range and fracture threshold for western European (Belgian) postmenopausal females.
Reginster, Jean-Yves ULg; Janssen, C; DEROISY, Rita ULg et al

in Clinical Rheumatology (1995), 14(1), 68-75

Bone mineral density (BMD) of the spine and the different regions of interest (ROI) of the hip were measured by dual energy X-ray absorptiometry in 278 healthy Belgian postmenopausal women and 93 ... [more ▼]

Bone mineral density (BMD) of the spine and the different regions of interest (ROI) of the hip were measured by dual energy X-ray absorptiometry in 278 healthy Belgian postmenopausal women and 93 postmenopausal type I osteoporotic females in order to: a) determine the normal range for lumbar and hip BMD values; b) define an "hypothetical" fracture threshold in this population; c) determine the preferential region to be considered for clinical use in type I osteoporosis. In the normal subjects, there is a negative relationship (< 0.001) between age or time elapsed since menopause (Tm) and BMD measured at the level of the spine or at the ROI of the hip. For the spine, evidence of a curvilinear relationship was assessed. Regressions of BMD at the hip as a function of age or time elapsed since menopause, were best fitted by a linear relationship. In the population of postmenopausal women who have experienced a vertebral crush fracture, no relationships were observed between spine BMD and age or Tm but the osteoporotic women had a spine BMD significantly lower compared to age-matched normal controls: Z-score = -1.2 +/- 0.6 (mean +/- SD) (p < 0.0001). Fracture threshold calculated as the 90th percentile of spine BMD measured in osteoporotic patients was 0.840 g/cm2, corresponding to the mean value -1 SD for a population of women aged 51 years. [less ▲]

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See detailBeyond Borders. West European Migration Policy towards the 21st Century de S. Collinson
Martiniello, Marco ULg

in Ethnic and Racial Studies (1995), 18(2), 421-422

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See detailRhythmic and Electrophysiological Study after Dynamic Cardiomyoplasty
RADERMECKER, Marc ULg; Waleffe, André ULg; Gobin, Eric ULg et al

in Pacing & Clinical Electrophysiology (1995), 18(5, Pt 1), 965-72

To question the possible proarrhythmic effects of cardiomyoplasty (CMP), six adult goats were submitted to rhythmic and electrophysiological (EP) study 15 days before and 8 months after a posteroanterior ... [more ▼]

To question the possible proarrhythmic effects of cardiomyoplasty (CMP), six adult goats were submitted to rhythmic and electrophysiological (EP) study 15 days before and 8 months after a posteroanterior clockwise CMP procedure using Medtronic Cardiomyostimulator (CMS) (SP1005) and electrodes (SP5528) and completion of a progressive stimulation protocol. Pre and postoperative screening included a surface ECG, 24-hour Holter monitoring, high amplitude and filtered QRS averaging, and invasive EP study performed in the postoperative period with the CMS "ON" and "OFF." One-hour Holter recording with desynchronization of the CMS was obtained. Comparison of pre and postoperative ECG and rhythmic data showed no significant difference. High amplitude QRS averaging did not evidence meeting the usual criteria of late potentials. EP values were stable in both conditions and the aggressive EP program did not show evidence of increased susceptibility to arrhythmias. Asynchronous cardiomyostimulation did not induce arrhythmias. Our data strongly suggest that provided meticulous surgical technique is used, CMP does not significantly interfere with the electrical characteristics of the normal goat heart. The procedure, despite the disturbances it provokes, does not seem to be arrhythmogenic. The function of the CMS was always appropriate, even under stressful EP conditions. [less ▲]

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See detailStructure and characterization of isopyoverdin from Pseudomonas putida BTP1 and its relation to the biogenetic pathway leading to pyoverdins.
Jacques, Philippe ULg; Ongena, MARC ULg; Gwose, I. et al

in Zeitschrift für Naturforschung. C, Journal of Biosciences (1995), 50(9-10), 622-9

Pyoverdin type siderophores produced by six fluorescent Pseudomonas strains isolated from different rhizospheres were purified and characterized. The purified ferri-pyoverdins were tested for their ... [more ▼]

Pyoverdin type siderophores produced by six fluorescent Pseudomonas strains isolated from different rhizospheres were purified and characterized. The purified ferri-pyoverdins were tested for their ability to promote the growth of other strains grown under iron deficiency conditions. Only the one obtained from Pseudomonas putida BTP1 did not act as a growth promoter. The structure of the BTP1 siderophore was elucidated by spectroscopic methods and degradation studies. It turned out that it contains a chromophore which differs from the one typical for pyoverdins insofar as it carries the carboxyl group in 3- rather than in 1-position ((3S)-5-amino-1,2-dihydro-8,9-dihydroxy-3H-pyrimido[1,2a]quinoline-3- carboxylic acid). The amino group of the chromophore is substituted with the 5-carboxyl group of L-glutamic acid and its carboxyl group with the N-terminus of the peptide L-Asp-L-Ala-L-Asp-D-N5-Ac-N5-OH-Orn-L-Ser-L-c-N5-OH-Orn. This isopyoverdin fits into the biogenetic scheme which postulates ferribactins as the precursors of pyoverdins. [less ▲]

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See detailConformational Analysis Of Non-Sulfonylurea Hypoglycemic Agents Of The Meglitinide Family
Lins, Laurence ULg; Brasseur, Robert ULg; Malaisse, Wj.

in Biochemical Pharmacology (1995), 50(11), 1879-84

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See detailHuman germinal center CD4+CD57+ T cells act differently on B cells than do classical T-helper cells.
Bouzahzah, F.; Bosseloir, A.; Heinen, Ernst ULg et al

in Developmental Immunology (1995), 4(3), 189-97

We have isolated two subtypes of helper T cells from human tonsils: CD4+CD57+ cells, mostly located in the germinal center (GC), and CD4+CD57- cells, distributed through the interfollicular areas but also ... [more ▼]

We have isolated two subtypes of helper T cells from human tonsils: CD4+CD57+ cells, mostly located in the germinal center (GC), and CD4+CD57- cells, distributed through the interfollicular areas but also present in the GC. In a functional study, we have compared the capacities of these T-cell subtypes to stimulate B cells in cocultures. In order to block T-cell proliferation while maintaining their activation level, we pretreated isolated T cells with mitomycin C prior to culture in the presence of B cells and added polyclonal activators such as PHA and Con A, combined or not with IL-2. Contrary to CD4+ CD57- cells, CD4+CD57+ cells did not markedly enhance B-cell proliferation. Even when sIgD.B cells typical of germinal center cells were tested, the CD4+CD57+ cells had no significant effect. This is in accordance with the location of these cells: They mainly occupy the light zones of the GC where few B cells divide. Even when added to preactivated, actively proliferating cells, CD4+CD57 cells failed to modulate B-cell multiplication. On the supernatants of B-cell-T-cell cocultures, we examined by the ELISA technique the effect of T cells on Ig synthesis. Contrary to CD57+ T cells, whose effect was strong, CD57- T cells weakly stimulated Ig synthesis. More IgM than IgG was generally found. Because CD57 antigen is a typical marker of natural killer cells, we tested the cytolytic activity of tonsillar CD4+CD57+ cells on K562 target cells. Unlike NK cells, neither CD4+CD57+ nor CD4+CD57- cells exhibit any cytotoxicity. Thus, germinal center CD4+CD57+ cells are not cytolytic and do not strongly stimulate either B-cell proliferation or Ig secretion. CD4+CD57- cells, however, enhance B-cell proliferation and differentiation, thus acting like the classical helper cells of the T-dependent areas. [less ▲]

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See detailLa transmission du chant chez le Pinson des arbres (Fringilla c. coelebs) : phase sensible et rôle des tuteurs chez les oiseaux captifs.
Metzmacher, Maxime ULg

in Alauda (1995), 63

Learning plays a key role (Thorpe 1954) in the way song pattern develops in the Chaffinch. In experiments conducted and related here by Léon Hakin, the rearing of young Chaffinches in the presence of ... [more ▼]

Learning plays a key role (Thorpe 1954) in the way song pattern develops in the Chaffinch. In experiments conducted and related here by Léon Hakin, the rearing of young Chaffinches in the presence of adults of the same species suggests that : - learning of song can be relatively precise ; the young imitate the song(s) heard from its « teachers » during this period. This confirms experiments done by other researchers under different conditions (Slater & Ince 1982, Thielcke & Krome 1989). Some differences may however occur, particurlarly the form of the reproduced syllabes and their rythm of emision. - during its second calendar year, a bird placed in a new sound atmosphere can acquire new phrases and, apparently, forget its previous repertory. - certain young birds build up their repertory by coping phrases from different individuals and copy many of them for fixing the tempo of their song. The aim of the discussion is to find the characteristics of the sensitive period, the importance of social interactions on the process of song learning, the building of a repertory and the formation of dialects. In the last two phenomena, a process of dynamic and selective restructuration appears to be implied. [less ▲]

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See detailRat heart-aorta cluster transplantation : a novel model to study transplant rejection
D'Silva, Milbhor; Candidas, D.; Lee, S. et al

in Transplant International (1995), (8), 298-306

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See detailSOURCE STRATEGIES AND THE MEDIATIZATION OF CLIMATE-CHANGE
Mormont, Marc ULg; Dasnoy, Christine ULg

in Media, Culture & Society (1995), 17(1), 49-64

A wide approach to the problem of science-media relations is taken in this study of the visibility of science in three >European countries. Differences of national cultures within France, Germany and ... [more ▼]

A wide approach to the problem of science-media relations is taken in this study of the visibility of science in three >European countries. Differences of national cultures within France, Germany and Belgium hod the key to the analysis. This paper explores the impact on the media's representation of climate change that derives from the variations in the balance of power between the press, its scientific sources and other actors, especially pressure groups whoa have interest in how science is represented. France and Germany are shown to have very different approaches scignificantly in distinctive models of the role of media held by scinetists. These models look to be based in what is termed a "spontaneous media sociology" that frame the webs of relations between media and their sources and have a feedback effect oin them. [less ▲]

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See detailKarel ende Elegast et la tradition folklorique
Varvaro, Alberto; Moreno, Paola ULg

in Moyen Age (Le) (1995), CI(1995), 259-275

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See detailInsulinotropic action of (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate. II. Ionophoretic and conformational aspects.
Malaisse, W. J.; Nadi, A. B.; Malaisse-Lagae, F. et al

in General Pharmacology (1995), 26(6), 1319-25

1. The non-sulphonylurea insulinotropic agent sodium (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) was found to display calcium ionophoretic activity in an artificial ... [more ▼]

1. The non-sulphonylurea insulinotropic agent sodium (2S)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) was found to display calcium ionophoretic activity in an artificial membrane model. 2. Conformation analysis indicated that a complex between calcium and KAD-1229, with a 1:2 stoichiometry, indeed displays favourable attributes for ionophoretic activity across a hydrophobic environment. 3. It is speculated that the ionophoretic property of KAD-1229 might participate to the remodelling of cationic fluxes evoked by this insulinotropic agent in pancreatic islet cells. [less ▲]

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See detailUrbanisme commercial et géographie
Merenne-Schoumaker, Bernadette ULg

in Revue Belge de Géographie (1995), 2(59), 307-315

The paper proposes a short reflection on the commercial planning issue. Five points will be considered : a definition of the urban planning field, a presentation of the methodological problems, the ... [more ▼]

The paper proposes a short reflection on the commercial planning issue. Five points will be considered : a definition of the urban planning field, a presentation of the methodological problems, the underscoring of the five major current challenges (new balance city center - out of town, central areas revival, traditional unplanned shopping center maintenance (or revival), local and neighbourhood centers maintenance, out of town developments planning), the first steps towards a new commercial policy, the analysis of the connections between commercial planning and geography. [less ▲]

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See detailTHEORY OF THE THERMAL-CONDUCTIVITY OF RE AL-2 COMPOUNDS
Rassili, Ahmed ULg; Ausloos, Marcel ULg

in Journal of Magnetism & Magnetic Materials (1995), 147(3), 341-345

On the basis of the variational method for transport coefficients we have calculated the thermal conductivity of RE Al-2-like systems as a function of temperature. The low-temperature limit obeys ... [more ▼]

On the basis of the variational method for transport coefficients we have calculated the thermal conductivity of RE Al-2-like systems as a function of temperature. The low-temperature limit obeys Matthiessen's rule 1/kappa = 1/kappa(ph) + 1/kappa(s) + 1/kappa(imp) where the three components are the contributions arising from e(-)-phonon, e(-)-localized spin and e(-)-impurity interactions, respectively. The temperature dependence of each term has been calculated, as well as the superposition of all three. The influence of the physical parameters (spin value, Debye temperature, cut-off wave vector, Fermi energy, etc.) is shown. The theory is in good agreement with reported data for GdAl2. [less ▲]

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See detailGH receptor gene TaqI RFLP and milk traits in Italian Holstein-Friesian and Simmental cattle.
Falaki, Mohamed; Renaville, Robert ULg; Sneyers, Myriam et al

in Journal of Animal Science (1995), 73(Suppl 1), 113

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See detailLa physiologie de la valvule mitrale
RADERMECKER, Marc ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(7), 289-91

Faisant suite à une revue de l'anatomie de l'appareil mitral, les auteurs envisagent la physiologie de la valvule mitrale en étudiant les quatre phénomènes distincts que sont la contraction auriculaire ... [more ▼]

Faisant suite à une revue de l'anatomie de l'appareil mitral, les auteurs envisagent la physiologie de la valvule mitrale en étudiant les quatre phénomènes distincts que sont la contraction auriculaire, la dynamique de l'anneau, les mouvements de la valvule et la dynamique du flux mitral, ainsi que le jeu des muscles papillaires. Cette subdivision didactique ne doit pas estomper le fait que c'est l'intégration de ces phénomènes qui contribue à l'efficacité de la valvule. [less ▲]

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See detailSYNTHESIS OF SIO2-TIO2 XEROGELS BY SOL-GEL PROCESS
Pirson, Anne-Marie ULg; MOHSINE, Abdel; Marchot, Pierre ULg et al

in Journal of Sol-Gel Science and Technology (1995), 4(3), 179-185

A new method to synthesize SiO2-TiO2 gels by sol-gel process has been developed. This technique uses tetraisopropylorthotitanate [Ti(O'Pr)(4)] and tetraethylorthosilicate [TEOS]: they are mixed in the ... [more ▼]

A new method to synthesize SiO2-TiO2 gels by sol-gel process has been developed. This technique uses tetraisopropylorthotitanate [Ti(O'Pr)(4)] and tetraethylorthosilicate [TEOS]: they are mixed in the same solvent and then directly hydrolysed. This one-step reaction is possible because of the use of 2-methoxyethanol, a protic polar solvent. This alcohol plays two different specific roles: it acts as a solvent as well as a stabilizer of titanium alkoxide towards the hydrolysis-precipitation reaction. So, by an accurate adjustment of the quantity of methoxyethanol in the mixture, we can control the reactivity of the titanium precursor. Monolithic and transparent xerogels were obtained whatever the composition. Three monolithic SiO2-TiO2 gels containing 20, 50 and 75 mol% of TiO2 were prepared and studied in details. By using the TG-DSC analysis, we can follow the evolution of the loss of water and organic residues. The structural evolution of gels during calcination is characterized by IR spectroscopy and X-Ray diffraction. [less ▲]

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See detailBehavior of interchromatin granules during the cell cycle.
Thiry, Marc ULg

in European Journal of Cell Biology (1995), 68(1), 14-24

We investigated at the ultrastructural level, by different cytochemical and immunocytological approaches, the behavior of interchromatin granules (IGs) during interphase and mitosis in two cell lines (HEp ... [more ▼]

We investigated at the ultrastructural level, by different cytochemical and immunocytological approaches, the behavior of interchromatin granules (IGs) during interphase and mitosis in two cell lines (HEp-2 and Ehrlich tumor cells). Identical results were found in all two cell types. In interphase cells, IGs group into irregular clusters of varying size. They are frequently associated with coiled bodies and homogeneous fibrillar bodies. Analysis of serial sections reveals that IG clusters occupy distinct regions within the nucleoplasm. During prophase, the aggregation of granules in these clusters gives rise to compact, spherical, granular structures. These disperse in the mitotic cytoplasm at the breakdown of the nuclear envelope. At early telophase, some of them come into close contact with the periphery of reforming nuclei. IG clusters reappear in the daughter nuclei only after the chromosomes have decondensed during late telophase. Concomitantly, the cytoplasmic granular structures disappear. During the cell cycle, IG are silver-stainable and EDTA-positive. They are also constantly labeled by the polyadenylate nucleotidyl transferase-immunogold technique for detecting RNA. These results support the view that IGs persist throughout the whole cell cycle. [less ▲]

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See detailEscape into Innocence: Ian McEwan and the Nightmare of History
Delrez, Marc ULg

in Ariel : A Review of International English Literature (1995), 26(2), 7-23

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See detailLes allogreffes veineuses pour sauvetage des membres inférieurs: espoirs et réalité
VAN DAMME, Hendrik ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(10), 433-42

La veine saphène interne est le matériel de pontage de premier choix pour les revascularisations de membres au-dessous du pli de l'aine. Elle n'est néanmoins pas disponible chez près de 20 % des candidats ... [more ▼]

La veine saphène interne est le matériel de pontage de premier choix pour les revascularisations de membres au-dessous du pli de l'aine. Elle n'est néanmoins pas disponible chez près de 20 % des candidats à une chirurgie infra-inguinale, soit parce qu'elle a déjà été utilisée antérieurement, soit à cause de varicose ou d'un calibre trop petit. Ces dernières années ont vu apparaître dans la littérature un regain d'intérêt pour la veine saphène allologue, prélevée chez un donneur d'organes ou préparée à partir de segments de veine saphène strippée. Les auteurs en discutent les avantages théoriques et les modalités de conservation. Des travaux expérimentaux ont été suivis par des séries cliniques encore limitées en nombre et en temps de suivi. Les auteurs en discutent les résultats publiés. Une courte série (12 cas) dans notre département est décrite. Cette expérience limitée et une revue exhaustive de la littérature permettent de conclure que les allogreffes veineuses sont à réserver pour les sauvetages de jambes (lésions infrapoplitées) lorsque la veine autologue n'est pas disponible, en tant que solution de dernier recours. [less ▲]

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See detailPain after laparoscopic cholecystectomy: characteristics and effect of intraperitoneal bupivacaine.
Joris, Jean ULg; Thiry, E.; Paris, P. et al

in Anesthesia and Analgesia (1995), 81(2), 379-84

Although pain after laparoscopic cholecystectomy is less intense than after open cholecystectomy, some patients still experience considerable discomfort. Furthermore, the characteristics of ... [more ▼]

Although pain after laparoscopic cholecystectomy is less intense than after open cholecystectomy, some patients still experience considerable discomfort. Furthermore, the characteristics of postlaparoscopy pain differ considerably from those seen after laparotomy. Therefore, we investigated the time course of different pain components after laparoscopic cholecystectomy and the effects of intraperitoneal bupivacaine on these different components. Forty ASA physical status grade I-II patients were randomly assigned to receive either 80 mL of bupivacaine 0.125% with epinephrine 1/200,000 (n = 20) or the same volume of saline (n = 20) instilled under the right hemidiaphragm at the end of surgery. Intensity of total pain, visceral pain, parietal pain, and shoulder pain was assessed 1, 2, 4, 6, 8, 24, and 48 h after surgery. Analgesic consumption was also recorded. Patient data were similar in the two groups. In the saline group, visceral pain was significantly more intense than parietal pain at each time point; visceral and parietal pain were greater than shoulder pain during the first 8 h postoperatively. Intraperitoneal bupivacaine did not significantly affect any of the different components of postoperative pain. Analgesic consumption was similar in the two groups. This study demonstrates that visceral pain accounts for most of the pain experienced after laparoscopic cholecystectomy. Intraperitoneal bupivacaine is not effective for treating any type of pain after laparoscopic cholecystectomy. [less ▲]

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See detailResults of an Exclusion Technique for Treatment of Abdominal Aortic Aneurysm
Marnette, J.M.; CREEMERS, Etienne ULg; TROTTEUR, Geneviève ULg et al

in Cardiovascular Surgery (1995), 3(1), 26-9

An exclusion technique for the treatment of abdominal aortic aneurysm was used in six patients considered to be at high operative risk mainly because of chronic pulmonary disease. There were no deaths or ... [more ▼]

An exclusion technique for the treatment of abdominal aortic aneurysm was used in six patients considered to be at high operative risk mainly because of chronic pulmonary disease. There were no deaths or immediate major complications. Thrombosis of the aneurysm was achieved in four of the six patients. However, in three cases, repeated percutaneous embolization was required to produce thrombosis. One patient developed a secondary rupture of a persisting infrarenal sac resulting from a patent inferior mesenteric artery. This patient was successfully managed by ligature of the infrarenal portion of the abdominal aorta through a median laparotomy. This study emphasizes the limits and the risks of the exclusion technique. [less ▲]

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See detailIndications et sélection du candidat aux implants
Geerts, Sabine ULg

in Actualités Dentaires de l'Université de Liège (1995), 17

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See detailEn Belgique, diverses modalités de pâturage pour des taurillons avant finition à l'auge
Dufrasne, Isabelle ULg; Gielen, Marc ULg; Limbourg, Pierre et al

in Fourrages (1995), 141

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See detailA comprehensive analysis of mid-term voltage stability
Van Cutsem, Thierry ULg; Jacquemart, Yannick; Marquet, Jean-Noël et al

in IEEE Transactions on Power Systems (1995), 10

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See detailLes aliments à objectif nutritionnel particulier chez les carnivores domestiques: les nouvelles directives de la Communauté Européenne et leur application pratique dans le cadre du traitement de l'obésité
Diez, Marianne ULg; Leemans, M.; Houins, G. et al

in Annales de Médecine Vétérinaire (1995), 139

Specific - purpose food in compagnion animals: the new directories of the European Community and practical use in the treatment of obesity. Specific - purpose foods are often suggested by veterinarians in ... [more ▼]

Specific - purpose food in compagnion animals: the new directories of the European Community and practical use in the treatment of obesity. Specific - purpose foods are often suggested by veterinarians in the treatment of many diseases in compagnion animals. From 01/07/95, the directories of the European Community are applied. The present paper gives a reading of these directories and comments on the characteristics of these foods, the specific - purpose objectives and their use. Finaly, a dietetical approach of obesity is described using the different types of specific-purpose foods actually on the mark. [less ▲]

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See detailRelative importance of the trophic and direct pathways on PCB contamination in the rotifer species Brachionus calyciflorus (Pallas)
Joaquim-Justo, Célia ULg; Gosselain, V; Descy, Jean-Pierre et al

in Hydrobiologia (1995)

To determine the contribution of food ingestion (trophic pathway) to PCB contamination of zooplankton in the river Meuse (Belgium), we used 14 C-labelled algae (Dictyosphaerium ehrenbergianum) to measure ... [more ▼]

To determine the contribution of food ingestion (trophic pathway) to PCB contamination of zooplankton in the river Meuse (Belgium), we used 14 C-labelled algae (Dictyosphaerium ehrenbergianum) to measure ingestion and assimilation rates in the rotifer species Brachionus calyciflorus . When the concentration of algae in the culture medium varied from 20 103 to 200 103 algal cells ml -1 (0.12 to 1 .18 mg C 1 - '), the Brachionus calyciflorus ingestion rate varied from 0 .25 ± 0 .12 to 1 .52 ± 0 .43 ng C ind -1 h-1 at 15 °C and from 0 .74 ± 0 .17 to 5 .93 ± 0.61 ng Cind-' h-1 at 20 °C . The assimilation efficiency (ratio of the assimilation rate to the ingestion rate) measured in a culture medium containing 200 103 algal cells ml`' was 55 .7 ± 5.8%. Since the PCB concentration measured in the phytoplankton of the river Meuse is about 3 pg PCBs g -1 D.W., the estimated PCB contamination of zooplankton ascribable to the trophic pathway ranges from 0 .22 ± 0 .17 to 1 .31 ± 0.77 jag PCBs g -1 D.W. at 15 °C and from 0.64 ± 0 .34 to 5 .10 ± 2 .10 pg PCBs g -1 D. W. at 20'C . The lower figure based on measurements effected at 20 ° C is comparable to the actual level measured in zooplankton samples collected in the river Meuse (0 .69 ± 0.20 pg PCBs g`' D.W.) . The applicability of the formula used in our estimate was checked in a 48-hour in vitro experiment in which the rotifers were fed contaminated algae . The PCB accumulation measured in the rotifers was found to coincide with the calculated PCB contamination . Additional experiments were carried out to determine the contribution of the direct pathway to PCB contamination of zooplankton living in the river Meuse (0.02 pg PCBs 1-1 of water; average dissolved organic matter : 3 mg C 1 -1 ). The PCB concentration in zooplankton resulting from direct uptake of PCBs from the water was estimated at 0 .19 ± 0.05 jug PCBs g -1 D.W. These results show that in zooplankton living in polluted ecosystems, PCBs are likely to accumulate via the trophic pathway to concentrations up to 30 times higher than by direct contamination . Furthermore, our estimates of PCB contamination via the trophic pathway coincide quite well with actual concentrations measured in situ . [less ▲]

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See detailPhospholipid-Binding And Lecithin-Cholesterol Acyltransferase Activation Properties Of Apolipoprotein-A-I Mutants
Holvoet, P.; Zhao, Za.; Vanloo, B. et al

in Biochemistry (1995), 34(41), 13334-42

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space ... [more ▼]

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space of Escherichia coli, were studied. The rate of turbidity decrease following mixing of apo A-I(delta Ala190-Gln243) with dimyristoylphosphatidylcholine (DMPC) vesicles at 23 degrees C was 10-fold lower than that of the other apo A-I proteins, confirming that the carboxy-terminal region of apo A-I plays a role in rapid lipid binding. The Stokes radii of reconstituted high-density lipoproteins (rHDL), containing dipalmitoylphosphatidylcholine and cholesterol, were larger for the three apo A-I mutants [6.3 nm for apo A-I(delta Leu44-Leu126), 6.1 nm for apo A-I(delta Glu139-Leu170), and 6.5 nm for apo A-I(delta Ala190-Gln243)] than for intact apo A-I (5.0 nm). The mutant rHDL all contained 4 apo A-I molecules per particle as compared to 2 for intact apo A-I. Circular dichroism measurements revealed 8 alpha-helices per apo A-I molecule, 5 per apo A-I(delta Leu44-Leu126), 6 per apo A-I(delta Glu139-Leu170), and 4 per apo A-I(delta Ala190-Gln243) molecule as compared to predicted values of 8, 5, 6, and 6 alpha-helices, respectively. [less ▲]

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See detailAn approach to corrective control of voltage instability using simulation and sensitivity
Van Cutsem, Thierry ULg

in IEEE Transactions on Power Systems (1995), 10

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See detailMethode d’évaluation radiologique du parage et de l’extremité digitée du cheval dans un plan frontal
Serteyn, Didier ULg; Miesen, M.; Caudron, I. et al

in Journal Européen de Maréchalerie (1995), 7

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See detailThe importance of liposomes as models and tools in the understanding of photosensitization mechanisms
Hoebeke, Maryse ULg

in Journal of Photochemistry and Photobiology B : Biology (1995), 28(3), 189-196

The various applications of liposomes in understanding photosensitization are described in this paper, with particular emphasis on the various kinds of information that these models allow to obtain in ... [more ▼]

The various applications of liposomes in understanding photosensitization are described in this paper, with particular emphasis on the various kinds of information that these models allow to obtain in phototherapy. Liposomes are simple vesicles in which an aqueous phase is enclosed by a phospholipidic membrane. They are suitable models mimicking specific situations occurring <br />m vivo and they allow study of the influence of physieochemieal, photobioiogieal and biochemical factors on the uptake of photosensitizers by tissues, their mechanisms of action and the subsequent photoinduced tumor necrosis. Moreover, solubilization of the sensitizer into the bilayer seems to improve its tumoral selectivity and its photodynamic efficiency. [less ▲]

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See detailPathophysiological response of bovine diaphragm function to gastric distension
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in Journal of Applied Physiology (1995), 78

Because of the anatomic association of an exceptionally bulky stomach with a striking compartmentation of the chest wall, leading to the most cranial insertion of the diaphragm among mammals, gastric ... [more ▼]

Because of the anatomic association of an exceptionally bulky stomach with a striking compartmentation of the chest wall, leading to the most cranial insertion of the diaphragm among mammals, gastric overdistension in the bovine species offers a unique pathophysiological condition for the diaphragm. The purpose of the present study was to determine whether increased intragastric pressure (Pga) (1, 2, 3, 4, and 5 kPa) leads to perturbations of respiratory and diaphragm function in calves. Changes in diaphragmatic strength and inspiratory action followed a biphasic pattern: 1) transdiaphragmatic pressure (Pdi) in response to constant bilateral maximal phrenic nerve stimulation at 30 Hz increased with moderate gastric distension and then fell abruptly as Pga continued to rise and 2) the magnitude of the ratio of the fall in pleural pressure to total Pdi was maintained up to a Pga amounting to 2 kPa but declined at higher pressures. We conclude that gastric distension in the bovine species provokes physiologically significant alterations of the diaphragm excitation-to-pressure generation coupling as well as of its capacity to convert Pdi into useful inspiratory pleural pressure. We suggest that these perturbations resulted from the combination of 1) altered tension-generating capacity due to compromised perfusion, 2) altered diaphragm geometry capable of altering tension-to-pressure generation coupling, and 3) modified coupling of the diaphragm with the chest wall that reduced its ability to drive inspiration [less ▲]

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See detailPostweaning housing conditions and partner preference and sexual behavior of neonatally ATD-treated male rats.
Bakker, Julie ULg; van Ophemert, J.; Slob, A. K.

in Psychoneuroendocrinology (1995), 20(3), 299-310

Male rats were neonatally treated with cholesterol or a substance that blocks the aromatization of testosterone to estradiol (1,4,6-androstatriene-3,17-dione: ATD). At weaning (21 days) they were either ... [more ▼]

Male rats were neonatally treated with cholesterol or a substance that blocks the aromatization of testosterone to estradiol (1,4,6-androstatriene-3,17-dione: ATD). At weaning (21 days) they were either housed alone or in small groups (2-3 animals) and tested for partner preference behavior (PPB) in adulthood. Choice was between an estrous female and an active male (Part I) and between an estrous female and an ATD-male (Part II). Tests were carried out in a 3-compartment box. Social isolation did not have major effects on PPB except when sexual interaction with the stimulus animals was prevented (Part I). In this case, isolates (ATD and control) showed higher preference scores (PS) for the estrous female and spent less time in the empty middle compartment. When the choice was between an estrous female and an ATD-male, partner PS decreased in all males, most clearly in ATD-males. The latter animals spent more time with the stimulus ATD-male than they had done in previous PPB tests with the normal stimulus male. In contrast to partner preference behaviors, sexual behavior was clearly affected by social isolation. Isolates (ATD and control) displayed lower frequencies of mounts and intromissions. These effects persisted over consecutive tests. Ejaculation was not affected. In conclusion, the present results confirm earlier findings about the significance of neonatal endocrine conditions for the organization of adult PPB in male rats. The presence or absence of social conspecifics after weaning appears to have little influence on adult PPB. [less ▲]

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See detailPathophysiological response of bovine pulmonary function to gastric distension
Desmecht, Daniel ULg; Linden, Annick ULg; Lekeux, Pierre ULg

in Journal of Comparative Pathology (1995), 112

The purpose was to determine whether gastric overdistension leads to lifethreatening perturbations of pulmonary gas exchange in healthy calves. Six animals were studied with normal (0 kPa) and increased ... [more ▼]

The purpose was to determine whether gastric overdistension leads to lifethreatening perturbations of pulmonary gas exchange in healthy calves. Six animals were studied with normal (0 kPa) and increased (1, 2, 3, 4 and 5 kPa) intragastric pressure (IGP). Changes in pleural pressures and peak expiratory flow paralleled those of IGP. Inspiratory pressure-time index remained stable throughout the insufflation process. Pulmonary function values were characterized by abrupt changes with increasing IGP. Tidal volume declined as IGP increased and, along with inspiratory flow, decreased abruptly with the highest pressure (5 kPa). Respiratory rate progressively increased up to an IGP of 4 kPa, then decreased by 30%, due to breath-holding at the end of inspiration. Minute volume increased with IGP up to 4 kPa, but dramatically declined at 5 kPa. Total pulmonary resistance remained stable throughout the insufflation process, whereas lung dynamic compliance fell abruptly to one-half of its baseline value at IGPs of 1 kPa and above. Arterial oxygen tension was maintained at an IGP of 1 kPa, slightly diminished at 2–3 kPa, and markedly decreased at 4–5 kPa. Hypercapnia and respiratory acidosis developed progressively with increasing IGP. Changes in arterial gases were probably due to a combination of (1) alveolar hypoventilation, caused by altered tidal to dead space volume ratio, inadequate central nervous system “drive”, altered effectiveness of inspiratory muscle action, or end-inspiratory breath-holding, and (2) ventilation to perfusion mismatch, caused by perfusion of collapsed lung units. In the range of IGPs used, standardized arterial pH did not decline below the control value, which suggests that perfusion of peripheral tissues remained sufficient, and that respiratory failure rather than cardiovascular failure may be the principal physiopathological effect of increased gastric pressure [less ▲]

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See detailAssessment of glucose metabolism in humans with the simultaneous use of indirect calorimetry and tracer techniques.
Tappy, L.; Paquot, Nicolas ULg; Tounian, P. et al

in Clinical Physiology (1995), 15(1), 1-12

Concomitant measurements of sytemic glucose delivery and carbohydrate oxidation are frequently performed in human investigations. Systemic glucose delivery (SGD) is usually determined using dilution of ... [more ▼]

Concomitant measurements of sytemic glucose delivery and carbohydrate oxidation are frequently performed in human investigations. Systemic glucose delivery (SGD) is usually determined using dilution of infused glucose tracers; net carbohydrate oxidation rate (net CHOOX) can be calculated from respiratory gas exchanges and urinary nitrogen excretion (indirect calorimetry); alternatively, glucose oxidation can be measured from labelled CO2 production during infusion of carbon-labelled glucose tracers. In this paper, the theory underlying the use of each of these techniques is briefly reviewed and qualitative differences are outlined. SGD represents the sum of hepatic glucogenolysis, gluconeogenesis from amino acids or glycerol, and, according to the glucose tracer used, glucose cycles (glucose-phosphate cycle, fructose-phosphate cycle, Cori and glucose-alanine cycles); systemic delivery of exogenous glucose after oral or i.v. glucose administration is also measured. Net CHOOX represents oxidation of glucose arising from hepatic or muscle glycogen or from exogenous glucose; it does not take into account oxidation of glucose formed from amino acids or glycerol, which is included in net protein or lipid oxidation. In contrast, isotopic determination of glucose oxidation corresponds to oxidation of glucose originating from hepatic glycogen breakdown, of exogenously administered glucose, and of glucose formed from amino acids and glycerol. Non-oxidative glucose disposal, calculated as SGD-net CHOOX, corresponds to the sum of gluconeogenesis from amino acids or glycerol (which are included in net protein and lipid oxidation), glucose cycles, and glycogen synthesis. [less ▲]

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See detailApproche thérapeutique du cancer épithélial de l'ovaire au CHU Sart Tilman : Conclusions de la réunion interdisciplinaire du 22 mars 1995
Jerusalem, Guy ULg; Detroz, Bernard ULg; Herman, Philippe ULg et al

in Revue Médicale de Liège (1995), 50

Notre but est de définir une approche multidisciplinaire permettant d'offrir les meilleures chances de guérison ou de survie prolongée aux patientes. Nous nous sommes basés sur notre expérience ... [more ▼]

Notre but est de définir une approche multidisciplinaire permettant d'offrir les meilleures chances de guérison ou de survie prolongée aux patientes. Nous nous sommes basés sur notre expérience personnelle et les données actuelles de la littérature, tout en intégrant les approches innovatrices (ex : chimiothérapie intrapéritonéale précoce). Pour certaines patientes, le pronostic reste trop sombre avec un traitement standard et il nous semble important de leur proposer un traitement potentiellement plus efficace. [less ▲]

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See detail- Establishment of normal and transformed root cultures of Artemisia annua L. for artemisinin production.
Jaziri, M.; Shimomura, K.; Yoshimatsu, K. et al

in Journal of Plant Physiology (1995), 145(1-2), 175-177

Transformed cultures of Artemisia annua L. (Asteraceae) were established by the co-culture method using leaf segments of A. annua and Agrobacterium rhizogenes NCIB 8196 or MAFF 03-01724. The hairy root ... [more ▼]

Transformed cultures of Artemisia annua L. (Asteraceae) were established by the co-culture method using leaf segments of A. annua and Agrobacterium rhizogenes NCIB 8196 or MAFF 03-01724. The hairy root clones thus obtained grew vigorously on hormone-free medium, showing the typical transformed morphology. The genetic transformation of the root was proved by the opine assay. Normal root and shoot cultures were also established. A highly specific and sensitive enzyme-linked immuno-sorbent assay (ELISA) method was used for the detection and semi-quantitative determination of artemisinin and structurally related compounds in these cultures. The presence of artemisinin was confirmed by gas chromatography coupled to mass spectrometry (GC-MS) analysis. The hairy roots cultured in the dark produced no detectable level of artemisinin as shown by the adventitious shoots cultured under light conditions. The ELISA analysis of the green hairy roots cultured in liquid medium under a 16 h light/day photoperiod showed the existence of compound(s) structurally related to artemisinin, though normal and hairy roots cultured in the dark give no detectable levels of immuno-signal. [less ▲]

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See detailSerological and cutaneous testing of bovine tuberculosis with the A60 antigen complex from Mycobacterium bovis, strain Calmette-Guérin
Saegerman, Claude ULg

in Preventive Veterinary Medicine (1995), 23

A60, a major thermostable macromolecular antigen complex of Mycobacterium bovis strain Calmette-Guerin (BCG), is immunodominant in tuberculosis and able to elicit both humoral and cellular immune ... [more ▼]

A60, a major thermostable macromolecular antigen complex of Mycobacterium bovis strain Calmette-Guerin (BCG), is immunodominant in tuberculosis and able to elicit both humoral and cellular immune reactions in infected hosts. A60-based ELISA and cutaneous tests have been used, in conjunction with the PPD-based skin reaction, in a control group of healthy animals, and in a herd including tuberculous animals. Cutaneous testing with A60 yielded results comparable with those with PPD: both were negative with control cattle and positive with infected animals. Moreover, comparative cutaneous testing with avian tuberculin yielded similar results with PPD and A60. When animals from the infected herd were tested with both avian and bovine sensitins, 54% of cattle were diagnosed as fully positive, 26% suspect, and 20% negative. Serological analysis with the A60-ELISA of part of the infected herd yielded 74% positive, 21% suspect and 5% negative results. Thus, positivity was 74% for serological analysis and 54% for cutaneous testing, whereas positive plus suspect results were 95% for serological analysis and 80% for cutaneous testing. It can be concluded that A60 can be used in place of PPD for cutaneous testing in cattle, and that the diagnostic value of the A60-ELISA is superior to that of the PPD-cutaneous test. [less ▲]

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See detailLes ossements animaux de la villa gallo-romaine de Mageroy à Habay-la-Vieille
Mees, G; Gabriel, Annick ULg

in Arc-Hab., Bulletin trimestriel (1995), (9), 2-20

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See detailDes histoires du cinéma en images et en sons
Belloi, Livio ULg

in Iris - Revue de théorie de l'image et du son/A Journal of Theory on Image and Sound (1995), 19(automne), 75-98

Etude de quelques fictions réflexives (dont "Singin' in the Rain" de Stanley Donen et Gene Kelly) au travers desquelles, se mettant au miroir, le cinéma réfléchit sur sa propre histoire et sur ses jalons ... [more ▼]

Etude de quelques fictions réflexives (dont "Singin' in the Rain" de Stanley Donen et Gene Kelly) au travers desquelles, se mettant au miroir, le cinéma réfléchit sur sa propre histoire et sur ses jalons essentiels. [less ▲]

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See detailLa clé de saint Hubert
George, Philippe ULg; Weber, Georges ULg; martinot lucien

in Feuillets de la Cathédrale de Liège (1995)

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See detailPulmonary function changes induced by three regimens of bronchodilating agents in calves with acute respiratory distress syndrome
Genicot, Bruno; Close, Roland; Lindsey, J. K. et al

in Veterinary Record : Journal of the British Veterinary Association (1995), 137(8), 183-186

Two aerosolised bronchodilators, one sympathomimetic and one parasympatholytic, were tested either alone or in combination for their ability to improve the pulmonary function of double-muscled calves ... [more ▼]

Two aerosolised bronchodilators, one sympathomimetic and one parasympatholytic, were tested either alone or in combination for their ability to improve the pulmonary function of double-muscled calves suffering from acute respiratory distress syndrome. In control animals treated with 0.9 per cent saline the parameters of pulmonary function and signs of clinical distress did not change significantly within the hour following the first treatment. Among the other animals, both at one hour and seven days after the first treatment, the most clinical improvement was observed in the animals treated with both bronchodilators and the least in the animals treated with clenbuterol hydrochloride. One hour after the first treatment the respiratory system compliance of the animals treated with ipratropium bromide and the arterial oxygen tension of the animals treated with both bronchodilators were significantly enhanced. After seven days the resistive parameters, the rectal temperature and the respiratory rate were also significantly improved in the animals treated with ipratropium bromide or both bronchodilators whereas only the respiratory rate and rectal temperature were significantly reduced in the animals treated with clenbuterol hydrochloride. [less ▲]

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See detailLe rôle de l'industrie de l'assurance dans le pilotage de la sécurité privée et de la politique de prévention
Lemaître, André ULg

in Déviance et Société (1995), 19(N°2), 159-168

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See detailHYDRODYNAMIC SIMULATIONS OF GALAXY FORMATION .1. DISSIPATION AND THE MAXIMUM MASS OF GALAXIES
Thoul, Anne ULg; WEINBERG, D. H.

in Astrophysical Journal (1995), 442(2), 480-491

We describe an accurate, one-dimensional, spherically symmetric Lagrangian hydrodynamics/gravity code, designed to study the effects of radiative cooling and photoionization on the formation of ... [more ▼]

We describe an accurate, one-dimensional, spherically symmetric Lagrangian hydrodynamics/gravity code, designed to study the effects of radiative cooling and photoionization on the formation of protogalaxies. The code can treat an arbitrary number of fluid shells (representing baryons) and collisionless shells (representing cold dark matter). As a test of the code, we reproduce analytic solutions for the pulsation behavior of a poly-trope and for the self-similar collapse of a spherically symmetric, cosmological perturbation. In this paper we concentrate on the effects of radiative cooling, examining the ability of collapsing perturbations to cool within the age of the universe. In contrast to some studies based on order-of-magnitude estimates, we find that cooling arguments alone cannot explain the sharp upper cutoff observed in the galaxy luminosity function. [less ▲]

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See detailLiège aussi doit rêver. A propos d'un monument et d'une fontaine sur la place Saint-Lambert
George, Philippe ULg

in chronique de la société royale Le Vieux-Liège (1995)

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See detailAdhesion and costimulatory molecules on human FDC in vitro.
Tsunoda, R.; Heinen, Ernst ULg; Imai, Y. et al

in Advances in Experimental Medicine and Biology (1995), 378

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See detailMessenger RNA expression for a TSH receptor variant in the thymus of a two-year old child
Paschke, Ralf; Geenen, Vincent ULg

in Journal of Molecular Medicine (1995), 73577-580

We recently described the presence of a TSH receptor variant in orbital tissues. The presence of this TSH receptor variant in the thymus suggests that induction of immune tolerance to this TSH receptor ... [more ▼]

We recently described the presence of a TSH receptor variant in orbital tissues. The presence of this TSH receptor variant in the thymus suggests that induction of immune tolerance to this TSH receptor-transcript is possible. A lack of tolerance induction for this TSH receptor variant could provide an explanation for a possible antigenic link between Graves' disease and thyroid-associated orbitopathy. [less ▲]

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See detailAbility of Bronchodilators to Prevent Bovine Experimental Respiratory Distress
Genicot, Bruno; Lambert, Philippe ULg; Votion, Dominique ULg et al

in Veterinary Research (1995), 26(4), 276-283

This cross-over trial involving 6 Blue Belgian double-muscled calves aimed to investigate whether ipratropium bromide inhaled alone or in combination with clenbuterol hydrochloride could prevent the ... [more ▼]

This cross-over trial involving 6 Blue Belgian double-muscled calves aimed to investigate whether ipratropium bromide inhaled alone or in combination with clenbuterol hydrochloride could prevent the dramatic clinical and pulmonary disturbances that are observed during an experimentally induced bronchoconstriction. Inhaled bronchodilators significantly influenced the clinical and functional responses of bovines subjected to a 5-hydroxytryptamine perfusion. However, despite a mean (standard error) wash-out period of 11.2 (3.1) and 7.5 (0.9) d after the 1st and the 2nd one-day challenges, respectively, first-order carry-over effects (ie those remaining from the previous treatment), effects of the period during which the treatment was allocated and interaction effects did not allow a definitive interpretation of overall treatment differences. [less ▲]

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See detailStochastic generation of precipitation and effect on vegetation net primary production
Hubert, Benoît ULg; François, Louis ULg; Warnant, Pierre ULg

in Global Energy and Water Cycle Experiment news (1995), 5

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See detailLa pratique du traitement de texte appliquée à la conception de documents scientifiques
Deltenre, Alain; Claustriaux, Jean-Jacques ULg; Austraet, J.

in Notes de Statistique et d'Informatique (1995), (1), 1-27

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See detailExpertise scientifique et action publique : le cas du changement climatique dans trois pays européens
Mormont, Marc ULg; Dasnoy, Christine ULg

in Natures Sciences Sociétés (1995), 3(&), 16-25

L'expertise scientifique du changement climatique fait l'objet d'une réception très différente en France, en Allemagne et en Belgique. cet état de fait semble lié à la fois à des configurations politiques ... [more ▼]

L'expertise scientifique du changement climatique fait l'objet d'une réception très différente en France, en Allemagne et en Belgique. cet état de fait semble lié à la fois à des configurations politiques différentes, à des procédures spécifiques mais aussi aux stratégies des scientifiques lesquelles dépendent de leur anticipation de cette réception. Cette stratégie des "sources" d'information ne laisse pas de poser des questions sur l'expertise. [less ▲]

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See detailprésentation de : Abbé Lhomond, De viris (les grands hommes de Rome), Latin/français, traduit et présenté par J. Gaillard, Paris, 1995
Rochette, Bruno ULg

in Bulletin de la Fédération des Professeurs de Grec et de Latin [=FPGL] (1995), 99

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See detailPolitics in the lifeboat. Immigrants and the American Democratic Order de J.C. Harles
Martiniello, Marco ULg

in International Migration Review (1995), 28(108), 900-901

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See detailDescription et interprétation stratigraphique de quatre sondages dans le Secondaire de la Gaume (Neulimont, Aubange, Saint-Mard et Toernich)
Boulvain, Frédéric ULg; Delsate, D.; Maubeuge, P. L.

in Professional Paper Belgian Geological Survey (1995), 277

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See detailLocalization of varicella-zoster virus nucleic acids and proteins in human skin.
Nikkels, Arjen ULg; Debrus, S.; Sadzot-Delvaux, Catherine ULg et al

in Neurology (1995), 45(12 Suppl 8), 47-9

The pathogenic mechanisms involved in varicella-zoster virus (VZV) infections remain elusive. The pattern of cutaneous distribution of the IE63 protein and of the gpI (gE) and gpII glycoproteins with ... [more ▼]

The pathogenic mechanisms involved in varicella-zoster virus (VZV) infections remain elusive. The pattern of cutaneous distribution of the IE63 protein and of the gpI (gE) and gpII glycoproteins with their corresponding genome sequences during VZV infections was studied by immunohistochemistry and in situ hybridization. Skin biopsy specimens were obtained from immunocompetent and immunocompromised patients with varicella, herpes zoster, or atypical VZV lesions. The first evidence for VZV infection consisted of the presence of IE63 in keratinocytes. In the vesicles and pustules, the viral transcripts gpI, gpII, and IE63 and the corresponding nucleic acids for gpI and gpII were identified in keratinocytes, sebocytes, Langerhans cells, dermal dendrocytes, monocytes/macrophages, and endothelial cells. The gpI and gpII glycorpoteins were essentially located on the cellular membranes while IE63 expression was generally restricted to the nuclei. In three biopsies of early herpes zoster, viral proteins were disclosed in dermal nerves and in perineurial type I dendrocytes. This was never encountered in varicella. Vasculitic changes and endothelial cell involvement were more prominent in varicella than in herpes zoster. It is concluded that the secondary viremia in varicella that affects the dermal endothelial cells is followed by a cell-to-cell spread to keratinocytes. In herpes zoster, the viral progression through cutaneous nerves primarily extends to the pilosebaceous units with a secondary involvement of epidermal keratinocytes, followed by a further spread to dermal cells. [less ▲]

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See detailThe dexamethasone suppression test in violent suicide attempters with major depression.
Pitchot, William ULg; Hansenne, Michel ULg; Gonzalez Moreno, A. et al

in Biological Psychiatry (1995), 37(4), 273-4

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See detailEffects of glucocorticoids and sympathomimetic agents on basal and insulin-stimulated glucose metabolism.
Paquot, Nicolas ULg; Schneiter, P.; Jequier, E. et al

in Clinical Physiology (1995), 15(3), 231-40

The mechanisms responsible for glucocorticoid-induced insulin resistance remain unclear. Glucocorticoids show several interactions with the sympatho-adrenal system which may contribute to this decrease in ... [more ▼]

The mechanisms responsible for glucocorticoid-induced insulin resistance remain unclear. Glucocorticoids show several interactions with the sympatho-adrenal system which may contribute to this decrease in insulin sensitivity: they enhance the synthesis and actions of catecholamines, but abolish insulin-induced activation of muscle sympathetic nerve activity. The present study was performed in order to investigate the effects of the interactions between glucocorticoids and the sympatho-adrenal system on insulin sensitivity. Basal and insulin-stimulated glucose metabolism was measured in healthy human subjects during four 2-h clamp studies as follows: control (C); after taking oral dexamethasone (2 mg daily) for 2 days (D); after taking oral ephedrine sulphate (40 mg daily) for 2 days (E); and after taking dexamethasone+ephedrine (D+E). Glucose uptake, production and oxidation were calculated from plasma 13C glucose and exhaled 13CO2 during constant tracer infusion of U-13C glucose. Basal glucose production, utilization and oxidation were similar in all four studies. During hyperinsulinaemia, glucose uptake was reduced by 51.5% with treatment D, by 25.9% with treatment E, and by 49.6% with D+E. Glucose oxidation was reduced by 54.0% with treatment D, by 24.0% with treatment E, and by 57.2% with D+E. Hepatic glucose production was completely suppressed in all four studies. It is concluded that both dexamethasone and ephedrine decrease insulin-mediated glucose uptake and oxidation. Co-administration of ephedrine does not suppress the glucocorticoid-induced alterations of glucose metabolism. This indicates that glucocorticoid-induced insulin resistance is not related to the inhibition of muscle sympathetic nerve activity. These results suggest instead that glucocorticoids and sympathomimetic agents may impair glucose metabolism by common actions. [less ▲]

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See detailSatellite image maps of Warsaw in the scale 1 :25,000
Kaczynski, Rom; Donnay, Jean-Paul ULg; Muller, Fabrice

in EARSeL Advances in Remote Sensing (1995), 4(2), 100-103

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See detailTreatment of dysfunctional bleeding and fibroids by advanced endoscopic techniques with the Nd:YAG laser: from the present to the future.
Donnez, Jacques; Polet, Roland; Anaf, V. et al

in Bailliere's Clinical Obstetrics & Gynaecology (1995), 9(2), 329-45

Both the electrical current of the resectoscope and the energy of the Nd:YAG laser have been effective tools in the destruction of endometrial tissue to a sufficient depth to avoid regeneration. GnRH ... [more ▼]

Both the electrical current of the resectoscope and the energy of the Nd:YAG laser have been effective tools in the destruction of endometrial tissue to a sufficient depth to avoid regeneration. GnRH-agonist therapy effects a decrease in the total uterine cavity area which facilitates surgical treatment and reduces the risk of fluid overload syndrome. The recurrence rate of meno/metrorrhagia is higher when the uterine cavity is more than 10 cm2. The use of GnRH-agonists represents an adjunct for preoperative reduction of submucosal myomas so that subsequent hysteroscopic myomectomy is possible. A two-step hysteroscopic therapy combined with GnRH-agonist therapy is performed when the largest portion of the submucosal myoma is located in the uterine wall. In cases of numerous submucosal and intramural myomas, a laparoscopic supracervical hysterectomy is performed because of the high risk of recurrence after the hysteroscopic procedure. [less ▲]

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See detailGrowth hormone response to clonidine in nondepressed patients with a history of suicide attempts.
Pitchot, William ULg; Hansenne, Michel ULg; Moreno, A. G. et al

in Biological Psychiatry (1995), 38(3), 201-3

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See detailSuccessful abdominal aortic aneurysm resection in long-term survivors of cardiac transplantation.
Defraigne, Jean-Olivier ULg; SakalihasanN, Natzi ULg; DEMOULIN, Julie ULg et al

in Cardiovascular Surgery (1995), 3(3), 321-4

With the improvement of survival rates following cardiac transplantation, the probability of recipients developing extracardiac disease is increased. Three cases are reported of abdominal aortic aneurysm ... [more ▼]

With the improvement of survival rates following cardiac transplantation, the probability of recipients developing extracardiac disease is increased. Three cases are reported of abdominal aortic aneurysm successfully operated on in cardiac allograft recipients 1 to 4 years after transplantation. Indications for transplantation were valvular, idiopathic and ischaemic cardiomyopathy. Post-transplant hypertension and hyperlipidaemia may have played a role in the rapid growth of the aneurysms. Cardiac function and the incidence of graft atherosclerosis were assessed before surgery by coronary angiography. All three patients were discharged from hospital. Abdominal aortic aneurysm resection may be a safe procedure in cardiac transplant patients. In view of the rapid increase in the size of the aneurysms in transplanted patients, careful screening should be performed during follow-up. [less ▲]

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See detailProximal Migration of Vena Caval Filters: Report of Two Cases with Operative Retrieval
DEFRAIGNE, Jean ULg; Vahdat, Olivier; Lacroix, Hendrik et al

in Annals of Vascular Surgery (1995), 9(6), 571-5

Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle ... [more ▼]

Operative retrieval of two proximally migrated vena caval filters was performed in two patients, ages 42 and 45 years, respectively. In the first patient the filter was encrusted in the right ventricle, and in the second one the filter was found in the pulmonary artery. Both filters were retrieved under cardiopulmonary bypass via an incision in the right atrium and the pulmonary artery, respectively. These two observations underscore the risk of increased unwarranted indications and consequent higher complication rates of vena caval filters. [less ▲]

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See detailLa coarctation de l'aorte isthmique (a l'exception des urgences néonatales)
Limet, Raymond ULg

in Revue Médicale de Liège (1995), 50(7), 298-304

Même quand elle est une lésion isolée, la CA est une maladie grave qui altère l'espérance de vie. Les causes de mortalité sont les complications liées à l'hypertension, la rupture spontanée au niveau des ... [more ▼]

Même quand elle est une lésion isolée, la CA est une maladie grave qui altère l'espérance de vie. Les causes de mortalité sont les complications liées à l'hypertension, la rupture spontanée au niveau des dilatations pré- et poststénotiques, au niveau des intercostales, et les anévrysmes disséquants. Le traitement chirurgical, par résection-anastomose ou interposition de greffe, introduit il y a plus de 50 ans, est obéré d'une mortalité faible chez l'adulte (1,3 %). Il ne normalise pas toutefois l'espérance de vie du patient opéré, qui reste un patient à haut risque. Les complications tardives sont proportionnelles à l'importance de l'hypertension préopératoire et à l'âge du patient au moment de l'opération. La guérison de l'hypertension est mieux assurée si le patient a été opéré dans l'enfance. Le taux de resténose est élevé pour les CA opérées avant l'âge de deux ans. Un suivi cardio-vasculaire est indispensable chez tout opéré. [less ▲]

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See detailEvaluation bryologique d'un projet de réinondation par les crues du Rhin: l'exemple de la réserve naturelle d'Erstein (Alsace, France)
Vanderpoorten, Alain ULg; Klein, J. P.; De Zuttere, P.

in Belgian Journal of Botany (1995), 128

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See detailEffects of a new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism.
Oelkers, W.; Foidart, Jean-Michel ULg; Dombrovicz, N. et al

in Journal of Clinical Endocrinology and Metabolism (1995), 80(6), 1816-21

Combined hormonal oral contraceptives (OCs) may lead to a mild rise in blood pressure and body weight. In rare instances, large increments in blood pressure are measured. We investigated the effect of a ... [more ▼]

Combined hormonal oral contraceptives (OCs) may lead to a mild rise in blood pressure and body weight. In rare instances, large increments in blood pressure are measured. We investigated the effect of a combination of ethinyl estradiol (EE) plus a progestogen with antimineralocorticoid, i.e. natriuretic, properties [Drospirenone (DRSP)] on body weight, blood pressure, the renin-aldosterone system, atrial natriuretic factor, plasma lipids, and glucose tolerance. It is anticipated that this will lead to the development of an OC that does not raise body weight or blood pressure. Four groups of 20 women each received 30 micrograms EE plus 3 mg DRSP (group A), 20 micrograms EE plus 3 mg DRSP (group B), 15 micrograms EE plus 3 mg DRSP (group C), and, as a control OC, 30 micrograms EE plus 150 micrograms levonorgestrel (Microgynon, Schering; group D) for 6 months. During the OC-free control cycles before and after treatment and throughout treatment, the target parameters were measured. Between the pretreatment cycle and the sixth treatment cycle, mean body weight fell by 0.8 to 1.7 kg in groups A, B, and C (P < 0.05 vs. D), whereas it rose by 0.7 kg in group D. Systolic and diastolic blood pressures fell by 1-4 mm Hg in groups A, B, and C (significant for A and C vs. D) and increased by 1-2 mm Hg in group D. Renin substrate rose equally in all groups (P < 0.05), whereas PRA and plasma aldosterone rose significantly only in the DRSP groups, presumably due to sodium loss. In the DRSP groups, high density lipoprotein cholesterol rose (P < 0.05), in contrast to group D. Low density lipoprotein cholesterol fell slightly (P > 0.05), whereas triglyceride levels showed a stronger increase in the DRSP groups (P < 0.05) than in group D. All groups attained good cycle control; group A had the best. Side-effects were minimal. To our knowledge, this is the first report on a combined OC that leads to a small decrease in body weight and blood pressure. It may be especially beneficial for women susceptible for a gain in weight and a rise in blood pressure. The potential of a new oral contraceptive (OC) containing drospirenone (DRSP) to avert the moderate increases in body weight and blood pressure often associated with use of existing combined OCs was investigated in a study of four groups of 20 German women each. Group A received 30 mcg of ethinyl estradiol (EE) and 3 mg of DRSP, Group B was administered 20 mcg of EE and 3 mg of DRSP, Group C received 15 mcg of EE and 3 mg of DRSP, and Group D was given a standard OC containing 30 mcg of EE and 150 mcg of levonorgestrel. Between the pretreatment cycle and the last (sixth) treatment cycle, mean body weight fell by 0.8-1.7 kg in Groups A, B, and C, but rose by 0.7 kg in Group D. Systolic and diastolic blood pressures fell by 1-4 mm Hg in Groups A, B, and C and rose by 1-2 mm Hg in Group D. Renin substrate rose equally in all four groups, while plasma renin activity, plasma aldosterone, and high density lipoprotein cholesterol rose significantly only in the three DRSP groups and serum triglyceride levels were significantly higher in Group D than in the three DRSP groups. Glucose tolerance increases were similar in all four groups. Finally, all groups--but especially Group A--experienced good cycle control and there were no serious side effects. These findings suggest that a combined OC containing DRSP may be especially beneficial for women who have a tendency to gain weight or experience a rise in blood pressure while taking OCs. [less ▲]

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See detailSerum erythropoietin during autologous bone marrow transplantation: relationship to measures of erythroid activity.
Davies, S. V.; Fegan, C. D.; Kendall, R. et al

in Clinical & Laboratory Haematology (1995), 17(2), 139-44

Marked elevation of serum erythropoietin (sEPO) occurs following high dose chemotherapy for malignant disease. It has been proposed that the subsequent fall in sEPO constitutes a relative erythropoietin ... [more ▼]

Marked elevation of serum erythropoietin (sEPO) occurs following high dose chemotherapy for malignant disease. It has been proposed that the subsequent fall in sEPO constitutes a relative erythropoietin (EPO) deficiency, prompting trials of recombinant EPO to reduce red cell transfusion during chemotherapy. We have investigated these phenomena by serial estimations of reticulocytes and sEPO in 11 autologous marrow transplant recipients. sEPO reached two to five times baseline 0 to 5 days after transplant but the inverse relationship between sEPO and haematocrit was maintained. Observed to expected log sEPO (Epo ratio) rose and fell in parallel with sEPO, remaining greater than 1.0 throughout. A progressive fall in reticulocyte count during chemotherapy was followed by an increase during engraftment. The strong inverse relationships between reticulocytes and Epo ratio in the 10 days after initiating chemotherapy support the hypothesis that loss of EPO-receptor bearing erythroid precursors allows a rise in sEPO during chemotherapy. The elevation of Epo ratio levels during engraftment indicates that it is the availability of EPO-sensitive progenitors, rather than the supply of EPO, that limits the rate of resumption of erythropoiesis after high-dose chemotherapy. [less ▲]

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See detailThe Dissociative Ionization of Carbon Dioxide below 21.22 eV. A high Resolution PIPECO spectroscopic investigation.
Locht, Robert ULg

in International Journal of Mass Spectrometry and Ion Processes (1995), 148

The photoion-photoelectron spectrum of O+, CO+ and CO2+ has been investigated under high resolution conditions. The O+ ion production is found not to be restricted to the CO2+ (C2Sigma+/g,0,0,0 ... [more ▼]

The photoion-photoelectron spectrum of O+, CO+ and CO2+ has been investigated under high resolution conditions. The O+ ion production is found not to be restricted to the CO2+ (C2Sigma+/g,0,0,0) predissociation. The (0,1,0) and (1,0,0) levels are clearly shown to be involved. The CO+ ion production involves all the vibrational states reached in the Franck-Condon region, i.e. up to (2,0,1) at 19.94 eV. The CO2+ molecular ion does not survive the predissociation in the entire range covered in the present work. [less ▲]

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See detailAutonomie de la volonté et statut personnel
Carlier, Jean-Yves ULg

in Cahiers des droits maghrébins (1995)

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See detail"L'effervescence a gagné la cité". A propos d'un monument et d'une fontaine sur la place Saint-Lambert
George, Philippe ULg

in Chronique de la Société Royale Le Vieux-Liège (1995)

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See detailThe quark propagator from the Dyson-Schwinger equations: (I). The chiral solution
Cudell, Jean-René ULg; Gentles, A. J.; Ross, D. A.

in Nuclear Physics B (1995), 440

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See detailPersonal name anomia: A single case study
Fery, P.; Vincent, Eric ULg; Brédart, Serge ULg

in Cortex (1995), 31

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See detailInfluence de la densité osseuse généralisée en implantologie orale
PTAK, Jean ULg; Legrand, Roman; Albert, Adelin ULg et al

in Actualités Odonto-Stomatologiques (1995), 189

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See detailMaledictio adversus ecclesiaeDei persequtores. A propos d'un ouvrage récent
George, Philippe ULg

in Revue Belge de Philologie et d'Histoire (1995), LXXIII

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See detailProtective Effect of Various Antagonists of Inflammatory Mediators against Paraoxon-Induced Pulmonary Edema in the Rabbit
Delaunois, Annie ULg; Gustin, Pascal ULg; Vargas, M. et al

in Toxicology and Applied Pharmacology (1995), 132(2), 343-345

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The ... [more ▼]

The protective effect of some antagonists of various inflammatory mediators against paraoxon-induced increases in endothelial permeability has been investigated in isolated perfused rabbit lungs. The edema induced by paraoxon has been previously related to a chain reaction mediated by acetylcholine. Lungs were ventilated and blood-free perfused with a constant flow. Arterial and venous pressures and lung weight were continuously recorded. Endothelial permeability was evaluated by measuring the capillary filtration coefficient (Kf,c). Paraoxon (4 x 10(-4) M) was injected in the perfusion circuit, in lungs with or without pretreatment with atropine, ketanserin, clonidine, morphine, indomethacin, and terfenadine plus cimetidine. Paraoxon induced a time-dependent increase in the Kf,c, a maximal effect being recorded 60 min after the injection. All the antagonists used as pretreatment significantly reduced the maximal effect recorded after paraoxon. These results show that muscarinic receptor antagonists, inhibitors of neuropeptides release, cyclooxygenase inhibitors, and 5-hydroxytryptamine and histamine receptor antagonists can protect the lung against the edema induced by paraoxon. This protective effect is due to inhibition of the chain reaction triggered by acetylcholine. [less ▲]

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See detailStreptomyces K15 active-site serine DD-transpeptidase: specificity profile for peptide, thiol ester and ester carbonyl donors and pathways of the transfer reactions.
Grandchamps, Jacqueline; Nguyen-Distèche, Martine ULg; Damblon, Christian ULg et al

in Biochemical Journal (1995), 307(Pt 2), 335-339

The Streptomyces K15 transferase is a penicillin-binding protein presumed to be involved in bacterial wall peptidoglycan crosslinking. It catalyses cleavage of the peptide, thiol ester or ester bond of ... [more ▼]

The Streptomyces K15 transferase is a penicillin-binding protein presumed to be involved in bacterial wall peptidoglycan crosslinking. It catalyses cleavage of the peptide, thiol ester or ester bond of carbonyl donors Z-R1-CONH-CHR2-COX-CHR3-COO- (where X is NH, S or O) and transfers the electrophilic group Z-R1-CONH-CHR2-CO to amino acceptors via an acyl-enzyme intermediate. Kinetic data suggest that the amino acceptor behaves as a simple alternative nucleophile at the level of the acyl-enzyme in the case of thiol ester and ester donors, and that it binds to the enzyme.carbonyl donor Michaelis complex and influences the rate of enzyme acylation by the carbonyl donor in the case of amide donors. Depending on the nature of the scissile bond, the enzyme has different requirements for substituents at positions R1, R2 and R3. [less ▲]

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See detailThe Anatolian Middle Palaeolithic. New Research at Karain Cave
Otte, Marcel ULg; Yalçinkaya, Isin; Taskiran, Harun et al

in Journal of Anthropological Research (1995), 51(4), 287-299

The aims of this report are three-fold: i. to provide new informattion concerning the Palaeolithic of Turkey; ii. to present the shifts in lithic techniques évidenced during this period; and iii. to ... [more ▼]

The aims of this report are three-fold: i. to provide new informattion concerning the Palaeolithic of Turkey; ii. to present the shifts in lithic techniques évidenced during this period; and iii. to demonstrate significance of the new information for interpreting long distance relations between Western Asia and Europe. In fact, in spite of the crucial geographic situation of Anatolia between the Near East and Europe, it has rarely been the subject of intensive excavations and publications concerning the Paleolithic periods. Recently obtained data are therefore of significant interest. [less ▲]

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See detailActivation of leucocytes after prolonged physical exercise
Bury, Thierry ULg; PIRNAY, Freddy ULg

in Mediators of Inflammation (1995), 4

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See detailAnalysis of learning tasks proposed within a volleyball teaching unit in secondary education. Comparison between two teachers differentiated by their expertise
Cloes, Marc ULg; Lapierre, Annick; Piéron, Maurice

in International VolleyTech (1995), 4

School physical education focussed on the harmonious development of the individual's various components - namely his motor, cognitive, affective and social dimensions. Within the French-speaking Community ... [more ▼]

School physical education focussed on the harmonious development of the individual's various components - namely his motor, cognitive, affective and social dimensions. Within the French-speaking Community of Belgium, as in many other regions in the world, the practive of voleyball comes within the activities proposed in the physical education programme of secondary education. The analysis of activites put forward by physical education teachers shows that volayball is the most practised collective sport in secondary education... [less ▲]

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See detailThe interchromatin granules.
Thiry, Marc ULg

in Histology and Histopathology (1995), 10(4), 1035-45

In the present review, we report on the data obtained on the most prominent elements observed in the interchromatin spaces: the interchromatin granules (IGs). Special emphasis is placed on the recent ... [more ▼]

In the present review, we report on the data obtained on the most prominent elements observed in the interchromatin spaces: the interchromatin granules (IGs). Special emphasis is placed on the recent contributions of immunocytochemical and in situ hybridization methods towards elucidating the composition and the behavior of these nuclear substructures during the cell cycle. The possible roles of IGs in the cell nucleus are also discussed. [less ▲]

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See detailGnawing induced by dopaminergic mobilzation : differential effects of direct and indirect dopamine agonists in mice
Tirelli, Ezio ULg; Witkin, J. M.

in Journal of Pharmacology and Experimental Therapeutics (The) (1995), 273

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See detailAdvanced laparoscopic surgery for the removal of rectovaginal septum endometriotic or adenomyotic nodules.
Donnez, Jacques; NISOLLE, Michelle ULg

in Bailliere's Clinical Obstetrics & Gynaecology (1995), 9(4), 769-74

In the pelvis, three different forms of endometriosis (Donnez et al, 1992) must be considered: (1) peritoneal, (2) ovarian, (3) rectovaginal septum. By evaluation of the mitotic activity and the stromal ... [more ▼]

In the pelvis, three different forms of endometriosis (Donnez et al, 1992) must be considered: (1) peritoneal, (2) ovarian, (3) rectovaginal septum. By evaluation of the mitotic activity and the stromal vascularization, we have recently suggested (Nisolle et al, 1993) that peritoneal red lesions were the most aggressive form of the disease and progress to the so-called typical or black lesion, which must be considered as an enclosed implant surrounded by fibrosis. This type of infiltration must be clearly differentiated from the rectovaginal endometriotic nodule. Koninckx (1993) recently described three types of deep-infiltrating endometriosis: deep-infiltrating endometriosis of type I is a rather large lesion in the peritoneal cavity, infiltrating conically with the deeper parts becoming progressively smaller. It has been suggested that this type of endometriosis is caused by infiltration. In type II lesions, the main feature is that bowel is retracted over the lesion which thus becomes deeply situated in the rectovaginal septum although not actually infiltrating it. Type III lesions are the deepest and most severe. They are spherically shaped, situated deep in the rectovaginal septum, often only visible as a small typical lesion at laparoscopy or often not visible at all. This lesion is often more palpable than visible and is acutely tender if the patient is examined at the time of menstruation, and gives rise to severe dyspareunia. In our experience there are two different types of 'deep-infiltrating endometriosis': 1. True deep-infiltrating endometriosis caused by the invasion of a very active peritoneal lesion deep in the retroperitoneal space. In cases of lateral peritoneal invasion, uterosacral ligaments can be involved as well as the anterior wall of the rectosigmoid bowel junction resulting in a retraction, adhesions and secondary obliteration of the cul-de-sac. 2. Pseudo deep-infiltrating endometriosis or adenomyosis of the rectovaginal septum. This lesion originates from the rectovaginal septum tissue and consists essentially of smooth muscle with active glandular epithelium and scanty stroma. In our study, the rectovaginal nodule was histologically similar to an adenomyoma (Zaloudek and Norris, 1987). It was a circumscribed, nodular aggregate of smooth muscle, endometrial glands and endometrial stroma. As in the 'adenomyoma', secretory changes were frequently absent in 'endometriotic' rectovaginal nodules. The invasion of the muscle by a very active glandular epithelium, without stroma, proved that the stroma is not necessary for invasion in this particular type of pathology called adenomyosis. In some instances, it can be seen that the vaginal pluristratified epithelium was replaced by a glandular epithelium. The fact that ciliated cells were present and the co-expression of both vimentin and cytokeratin (Donnez and Nisolle, personal communication) proved the Mullerian origin of the nodule, where certain histological characteristics are completely different to those observed in peritoneal lesions (Nisolle et al, 1990). In our series, deep fibrotic tissue assumed to contain endometriosis was excised or vaporized from the anterior rectum with the aid of multiple rectovaginal examinations. Cul-de-sac dissection was followed by excision of deep fibrotic endometriosis, without cul-de-sac reconstruction. In three cases, the bowel lumen was entered. A comprehensive laparoscopic procedure, while not eradicating all the endometriosis, may result in considerable pain relief or a desired pregnancy. [less ▲]

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See detailA comparative study of quantitative shape analysis techniques in sedimentology
Pirard, Eric ULg; Hoyez, Bernard

in Zentralblatt für Geologie und Paläontologie. Teil I, Allgemeine, Angewandte, Regionale und Historische Geologie (1995), 1(H11/12), 1061-1066

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See detailDe la necessite des services d'urgence de la main.
CARLIER, Alain ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1995), 150(7-9), 268-80280-2

Microsurgical techniques have been able to realize anastomoses of small vessels and nerves, with a high rate of success when performed by teams involved in that field. This has changed the concept of ... [more ▼]

Microsurgical techniques have been able to realize anastomoses of small vessels and nerves, with a high rate of success when performed by teams involved in that field. This has changed the concept of surgery of the hand. Reconstruction aims now at a functional result. Organisation of emergencies in hand surgery requires facilitations: hand surgeons, equipment and a team on a 24-hour basis, able to operate any kind of hand trauma. Since 1979, Liege is affiliated to the European Federation. Advantages of the immediate repair are significant repair are significant: reduction of the permanent disability rate, and in many instances, return to work at the same position. In conclusion, early treatment of the injuries of the hand is very effective, but need to be performed by specialists in the field of hand surgery. [less ▲]

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