Advanced search

Browse ORBi by ORBi project The Open Access movement
ORBi is a project of

 References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 37601 to 37700 of 56353     372 373 374 375 376 377 378 379 380 381 382     Note sous corr., Bruxelles du 27 juin 2001 (affaire de la Crèche Clovis)Jacobs, Ann in Journal des Procès (2001), (419), 30-31Detailed reference viewed: 27 (5 ULg) Urethral sphincterotomy for delivery of a vesical calculus in the mare: a case reportDeleuze, Stefan ; Hanzen, Christian in Annales de Médecine Vétérinaire (2001), 145(6, Suppl. S), 373-376A case of a cystic calculus in a mare and the pathophysiology of urolithiasis are described. In this case a 268 g calculus measuring 9 x 6 cm was removed after urethro-sphincterotomy was performed on the ... [more ▼]A case of a cystic calculus in a mare and the pathophysiology of urolithiasis are described. In this case a 268 g calculus measuring 9 x 6 cm was removed after urethro-sphincterotomy was performed on the standing mare. [less ▲]Detailed reference viewed: 120 (10 ULg) Compte-rendu de Bruce Bégout, La généalogie de la logique. Husserl, l'antéprédicatif et le catégorialLeclercq, Bruno in Recherches Husserliennes (2001), 16Detailed reference viewed: 137 (1 ULg) Practical Aspects Of Computational Chemistry Calculations Through Pc Networks: The Ramses-Beowulf ImplementationBeuve-Mery, D.; Rahman, M.; Ducarme, P. et alin Journal of Computational Chemistry (2001), 22(2), 172-7We have built clusters of PC using up to 320 processors in parallel. The first cluster was built in 1996 from 64 computers. The parallel architectures are named RAMSES. In this article, we share our ... [more ▼]We have built clusters of PC using up to 320 processors in parallel. The first cluster was built in 1996 from 64 computers. The parallel architectures are named RAMSES. In this article, we share our experience and discuss our choices. The architecture is composed of Pentium processors connected by a 100 Mbits/s Ethernet network. Because RAMSES are built of independent computers, the system is easily maintained, and can be modified by adding or removing machines. Two programs, which are dedicated to molecular modeling and were previously developed on single machines (OSIRIS and IMPALA), have been adapted. IMPALA models peptide and protein interaction with membranes, OSIRIS simulates an ab initio folding of globular proteins. After parallelization, each program consists of two parts: one is the human/RAMSES interface, and the second is the simulation per se. The parallel architecture is transparent for the users. Tests of the IMPALA and OSIRIS efficiencies are shown and discussed. [less ▲]Detailed reference viewed: 23 (0 ULg) Mechanism of Collisional Heating in Electrospray Mass Spectrometry: Ion Trajectory CalculationsHoxha, Antuan; Collette, Caroline ; De Pauw, Edwin et alin Journal of Physical Chemistry A (2001), 105To simulate the multicollisional heating process taking place in the intermediate pressure region of an electrospray source, ion trajectory calculations have been preformed by introducing in the SIMION ... [more ▼]To simulate the multicollisional heating process taking place in the intermediate pressure region of an electrospray source, ion trajectory calculations have been preformed by introducing in the SIMION program a subroutine for handling the collision dynamics. The simulated internal energy distributions are compared with already available experimental distributions obtained by the "survival ion yield" method. [less ▲]Detailed reference viewed: 41 (4 ULg) Improved Quantification of Angiogenesis in the Rat Aortic Ring AssayBlacher, Silvia ; Devy, L.; Burbridge, M. F. et alin Angiogenesis (2001), 4(2), 133-42In vitro angiogenesis assays are essential for the identification of potential angiogenic agents and screening for pharmacological inhibitors. Among these assays, the rat aortic ring model developed by ... [more ▼]In vitro angiogenesis assays are essential for the identification of potential angiogenic agents and screening for pharmacological inhibitors. Among these assays, the rat aortic ring model developed by Nicosia bridges the gap between in vivo and in vitro models. The quantification of angiogenesis on this system must be applicable to characterise vascular networks of various states of complexity. We present here an improved computer-assisted image analysis which allows: (1) the determination of the aortic ring area and its factor shape; (2) the number of microvessels, the total number of branchings, the maximal microvessel length and the microvessel distribution; (3) the total number of isolated fibroblast-like cells and their distribution. We show that this method is suitable to quantify spontaneous angiogenesis as well as to analyse a complex microvascular network induced by various concentrations of vascular endothelial growth factor (VEGF). In addition, by evaluating a new parameter, the fibroblast-like cell distribution, our results show that: (1) during spontaneous angiogenic response, maximal fibroblast-like cell migration delimits microvascular outgrowth; and (2) the known angiogenic inhibitor Batimastat prevents endothelial cell sprouting without completely blocking fibroblast-like cell migration. Finally, this new method of quantification is of great interest to better understand angiogenesis and to test pro- or anti-angiogenic agents. [less ▲]Detailed reference viewed: 28 (7 ULg) Caractéristiques de la reproduction dans l’espèce caprineZarrouk, A.; Souilem, O.; Drion, Pierre et alin Annales de Médecine Vétérinaire (2001), 145This review pointed out the physiological basis of goat reproduction. So far assimilated to ewes, goats presented their own characteristics concerning the sexual activity and the endocrinology of ... [more ▼]This review pointed out the physiological basis of goat reproduction. So far assimilated to ewes, goats presented their own characteristics concerning the sexual activity and the endocrinology of pregnancy. The well understanding of goat particularities is essential to control cyclic activities and reproduction applicationCe travail passe en revue les bases physiologiques de la reproduction dans l’espèce caprine. Longtemps assimilée à la brebis, la chèvre présente des spécificités propres, tant sur le plan du déroulement des cycles sexuels que sur le plan de l’endocrinologie de la gestation. Une bonne connaissance des particularités de la reproduction dans cette espèce permet une meilleure maîtrise du contrôle du cycle sexuel et des techniques de la reproduction [less ▲]Detailed reference viewed: 336 (7 ULg) Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitroCalaora, Viviane; Rogister, Bernard ; Bismuth, Karen et alin Journal of Neuroscience (2001), 21Detailed reference viewed: 11 (1 ULg) Changes in peroxidase activity, and level of phenolic compounds during light-induced plantlet regeneration from Eucalyptus camaldulensis Dehn. nodes in vitroArezki, Ouoimare; Boxus, Philippe; Kevers, Claire et alin Plant Growth Regulation (2001), 33(3), 215-219Node cultures of Eucalyptus camaldulensis Dehn in Petri dishes in vitro under darkness in the presence of an auxin developed meristematic agglomerates (4 to 6 diameter), i.e. dense shoot clusters in which ... [more ▼]Node cultures of Eucalyptus camaldulensis Dehn in Petri dishes in vitro under darkness in the presence of an auxin developed meristematic agglomerates (4 to 6 diameter), i.e. dense shoot clusters in which outgrowth of numerous successive buds is limited. Similar cultures under a 16 photoperiod produced small green plantlets with reduced leaves often presenting white hypertrophied lenticels and very short roots crowning the stem bases. The use of half-litre glass vials under light allowed direct development of well-developed rooted plantlets, either in the presence of the same auxin or in the presence of a cytokinin. Light favoured an increase in phenolic compounds and a reverse variation of peroxidase activity during the culture cycles. These aspects are discussed in terms of a possible regulation of the endogenous auxin level through a light control of peroxidase activity and the level of phenolic compounds. [less ▲]Detailed reference viewed: 49 (5 ULg) Key criteria for the design of polymeric stabilizers for aqueous titanium dioxide dispersions of high solid contentCreutz, Serge; Jérôme, Robert in e-Polymers (2001), (14), 1-9Amphiphilic copolymers consisting of an animated hydrophobic block and a hydrophilic poly(sodium methacrylate) one have been synthesized with different structures and tested as stabilizers for aqueous ... [more ▼]Amphiphilic copolymers consisting of an animated hydrophobic block and a hydrophilic poly(sodium methacrylate) one have been synthesized with different structures and tested as stabilizers for aqueous dispersions of alumina coated titanium dioxide (80 wt.-% solid). The dispersion stability is ruled by the strength of the anchoring of the aminated block onto the pigment and by the dynamics of the micelles formed by the copolymer. Any decrease in the anchoring strength, for example as a result of higher steric hindrance for the adsorbing block or of random rather than blocky distribution of the aminated co-units, is detrimental to the dispersion stability and makes this stability more dependent on the copolymer composition. Indeed, the position and dynamics of the unimers micelles equilibrium then control the adsorption of the copolymer on the pigment during the grinding process. [less ▲]Detailed reference viewed: 47 (2 ULg) The Vacuum UV Photoabsorption spectrum of Methyl Chloride (CH3Cl) and its perdeuterated Isotopomer CD3Cl. II. A vibrational Analysis.Locht, Robert ; Leyh, Bernard ; Hoxha, A. et alin Chemical Physics (2001), 272The fine structure of the vacuum UV photoabsorption spectrum of CH3Cl and CD3Cl has been analyzed in the 7.5-10.5 eV photon energy range. A large number of lines have been observed, classified and ... [more ▼]The fine structure of the vacuum UV photoabsorption spectrum of CH3Cl and CD3Cl has been analyzed in the 7.5-10.5 eV photon energy range. A large number of lines have been observed, classified and assigned to vibrational excitation accompanying a series of Rydberg transitions. The vibronic transitions involve both Jahn-Teller distortion and spin-orbit splitting. The former effect has been evaluated by ab initio calculations showing that the 2E state (in the C3v symmetry group) splits into 2A' and 2A" states in the Cs symmetry group. The 2A' state is energetically the lowest component whereas the 2A" is found to be a transition state. The Jahn-Teller stabilisation energy and the wavenumbers associated with all vibrational modes have been calculated. Experimentally, the entire fine structure could be described by using the vibrational modes, i.e. hcomega5= 104+/-7 meV, hcomega6= 77+/-7 meV and homega=162+/-3 meV respectively, as resulting from an average over all the analyzed Rydberg states. In CD3Cl the corresponding energies are hcomega5= 81+/-4 meV, hcomega6= 66+/-5 meV and hcomega= 124+/-4 meV. These values are in good agreement with those predicted by the present ab initio calculations for the ion ground state. However, the agreement is not so good for the wavenumber omega which could be assigned to the nu3 or nu4 vibrational modes. Though some arguments favour nu4 (the CH3 umbrella mode), within the error limits on the present measurements it is formally not possible to ascribe this wavenumber to one of these two vibrations. [less ▲]Detailed reference viewed: 78 (7 ULg) De l'utilisation pédagogique d'Internet dans l'enseignement secondaireHubert, Sylviane; Petit, Christelle; Demily, Fabian et alin Point sur la Recherche en Education (Le) (2001)Detailed reference viewed: 100 (7 ULg) Numeration systems on a regular language : Arithmetic operations, Recognizability and Formal power seriesRigo, Michel in Theoretical Computer Science (2001), 269Generalizations of numeration systems in which $$\N$$ is recognizable by a finite automaton are obtained by describing a lexicographically ordered infinite regular language $$L\subset \Sigma^*$$. For ... [more ▼]Generalizations of numeration systems in which $$\N$$ is recognizable by a finite automaton are obtained by describing a lexicographically ordered infinite regular language $$L\subset \Sigma^*$$. For these systems, we obtain a characterization of recognizable sets of integers in terms of $\N$-rational formal series. After a study of the polynomial regular languages, we show that, if the complexity of $$L$$ is $$\Theta (n^l)$$ (resp. if $$L$$ is the complement of a polynomial language), then multiplication by $$\lambda\in \N$$ preserves recognizability only if $$\lambda=\beta^{l+1}$$ (resp. if $$\lambda\neq (\#\Sigma)^\beta$$) for some $$\beta\in \N$$. Finally, we obtain sufficient conditions for the notions of recognizability for abstract systems and some positional number systems to be equivalent. [less ▲]Detailed reference viewed: 29 (2 ULg) Continuité de l'information, discontinuités sociales: NTIC, nouvelles formes d'organisation et dialogue socialSchoenaers, Frédéric ; Zune, Marcin Revue de Gestion des Ressources Humaines (2001), 42Detailed reference viewed: 88 (18 ULg) Recent biogeographic and ecological studies on otter (Lutra lutra) and European mink (Mustela lutreola) in Francede Bellefroid, Marie des Neiges; Libois, Roland ; Rosoux, Renéin Säugetierkundliche informationen (2001), 25Otter and European mink are two threatened species in France. The mink is even considered to be on the verge of extinction. Studies have been carried out for more than ten years to attempt to understand ... [more ▼]Otter and European mink are two threatened species in France. The mink is even considered to be on the verge of extinction. Studies have been carried out for more than ten years to attempt to understand the changes in their distribution and the ecological needs of these two semi-aquatic mustelids. The results of the research programmes completed or still under way, are presented. The French Ministry of Environment has set up two specific restoration plans, with the contribution of Conversation societies for wild fauna and scientific institutions. [less ▲]Detailed reference viewed: 64 (11 ULg) La réforme de la procédure fiscale : le point de vue de la Cour d’arbitrageOrban, Lionel in Fiscalité 2001. Le point sur les réformes », Journée d’études du Mercredi 31 octobre 2001, organisée par le Service de droit fiscal de la Faculté de droit de l’Université de Liège (2001)Detailed reference viewed: 27 (0 ULg) Imidazolopyrazinones as potential antioxydantsDevillers, Ingrid; Dive, Georges ; De Tollenaere, Catherine et alin Bioorganic & Medicinal Chemistry Letters (2001), 11(17), 2305-2309Detailed reference viewed: 10 (1 ULg) Coordinated regulation of procollagens I and III and their post-translational enzymes by dissipation of mechanical tension in human dermal fibroblasts.Lambert, Charles ; Colige, Alain ; Lapiere, C. M. et alin European Journal of Cell Biology (2001), 80(7), 479-85Mechanical tension governs fibroblast proliferation and survival and the homeostasis of the extracellular matrix to adapt its resistance to the mechanical requirements of the organs. To consolidate this ... [more ▼]Mechanical tension governs fibroblast proliferation and survival and the homeostasis of the extracellular matrix to adapt its resistance to the mechanical requirements of the organs. To consolidate this view, we analysed the effect of tension release on the expression of molecules involved in the architecture and stabilisation of the collagen fibres, namely the procollagens type I and III, the amino- and carboxy-procollagen peptidases (N-pCP and C-pCP) and lysyl oxidase. Cells were cultured in conditions of high mechanical stress in monolayer on a collagen coat and under reduced tension by disruption of the cytoskeleton upon treatment with cytochalasin D in monolayer on a collagen coat or by integrin-mediated stress relaxation in a freely retracting collagen gel. The mRNAs were measured by quantitative RT-PCR monitored by simultaneous reverse-transcription and amplification of an original internal standard. Tension relaxation resulted in a decreased expression of the procollagens type I and III, of the two expressed forms of C-pCP, of the two forms of N-pCP and of lysyl oxidase. Type III collagen, known to control diameter of the fibres, was less down-regulated than type I collagen. Interestingly, the expression of the two alternatively spliced forms of the N-pCP was dissimilarly regulated. These data suggest that mechanical tension may modulate the stiffness of the extracellular matrix by controlling not only the level of expression of its fibrillar constituents but also that of the enzymes participating in their extracellular processing and mechanical stabilisation. [less ▲]Detailed reference viewed: 20 (8 ULg) Effects of Brassicaceae secondary metabolites on the Glutathione S-transferase activity from Episyrphus balteatus De Geer (Diptera: Syrphidae)Vanhaelen, N.; Haubruge, Eric ; Francis, Frédéric in Pesticide Biochemistry & Physiology (2001), 71(3), 170-177Detailed reference viewed: 33 (1 ULg) Bulletin bibliographique de la Société Rencesvals 2000-2001Henrard, Nadine in Bulletin Bibliographique de la Société Rencesvals pour l'étude des épopées romanes (2001), (32), 1-237Detailed reference viewed: 10 (5 ULg) European Citizenship Practice - A. WienerMartiniello, Marco in Nations & Nationalism (2001), 7(1), 121-122Detailed reference viewed: 10 (0 ULg) All detectable high-molecular-mass penicillin-binding proteins are modified in a high-level beta-lactam-resistant clinical isolate of Streptococcus mitis.Amoroso, Ana Maria ; Demares, D.; Mollerach, M. et alin Antimicrobial agents and chemotherapy (2001), 45(7), 2075-81All detectable high-molecular-mass penicillin-binding proteins (HMM PBPs) are altered in a clinical isolate of Streptococcus mitis for which the beta-lactam MICs are increased from those previously ... [more ▼]All detectable high-molecular-mass penicillin-binding proteins (HMM PBPs) are altered in a clinical isolate of Streptococcus mitis for which the beta-lactam MICs are increased from those previously reported in our region (cefotaxime MIC, 64 microg/ml). These proteins were hardly detected at concentrations that saturate all PBPs in clinical isolates and showed, after densitometric analysis, 50-fold-lower radiotracer binding. Resistance was related to mosaic structure in all HMM PBP-coding genes, where critical region replacement was complemented not only by substitutions already reported for the closely related Streptococcus pneumoniae but also by other specific replacements that are presumably close to the active-site serine. Mosaic structure was also presumed in a pbp1a-sensitive strain used for comparison, confirming that these structures do not unambiguously imply, by themselves, detectable critical changes in the kinetic properties of these proteins. [less ▲]Detailed reference viewed: 9 (1 ULg) The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel.Oury, Cécile ; Toth-Zsamboki, Emese; Tytgat, Jan et alin Thrombosis and Haemostasis (2001)This letter indicates a lack of specificity of a platelet P2Y1 receptor antagonist.Detailed reference viewed: 16 (1 ULg) Optimisation of Stiffened StructuresRigo, Philippe in Dept. of Naval Architecture and Marine Engineering (2001)Detailed reference viewed: 51 (1 ULg) Administration of erythopoietin and granulocyte colony-stimulating factor in donor/recipient pairs to collect peripheral blood progenitor cells (PBPC) and red blood cell units for use in the recipient after allogeneic PBPC transplantation.Sautois, Brieuc ; Baudoux, Etienne ; Salmon, Jean et alin Haematologica (2001), 86(11), 1209-18BACKGROUND AND OBJECTIVES: It may be useful to reduce the exposure of transplant recipients to homologous blood. This may be achieved by procuring donor-derived red blood cell (RBC) units, collecting more ... [more ▼]BACKGROUND AND OBJECTIVES: It may be useful to reduce the exposure of transplant recipients to homologous blood. This may be achieved by procuring donor-derived red blood cell (RBC) units, collecting more peripheral blood progenitor cells (PBPC) with a combination of granulocyte colony-stimulating factor (G-CSF) + recombinant human erythropoietin (rHuEpo) and by administering rHuEpo post-transplantation. DESIGN AND METHODS: Eight ABO-compatible donors were treated with rHuEpo and intravenous iron to collect 12 RBC units for use in their recipients. PBPC were collected after mobilization with rHuEpo and G-CSF in the same donors. The recipients received G-CSF and rHuEpo post-transplantation. A control group of 10 donor/recipient pairs received G-CSF alone for PBPC mobilization and after the transplantation. RESULTS: Eighty-six out of 91 planned RBC units were collected in the donors without significant decrease in hematocrit because of a 4-fold increase in RBC production despite functional iron deficiency. After 2 leukaphereses, the cumulative yields of NC and CFU-GM were lower in the study group while those of BFU-E, CFU-Mix and CD34+ cells were similar. However, erythroid recovery was significantly accelerated in the study group. INTERPRETATION AND CONCLUSIONS: Collection of 12 RBC units within 6 weeks is feasible with rHuEpo and intravenous iron; this strategy allows a dramatic reduction in recipient exposure to homologous blood; rHuEpo has no synergistic effect with G-CSF for mobilization of PBPC in normal donors and may even be deleterious; and rHuEpo in the recipient may enhance erythroid engraftment. [less ▲]Detailed reference viewed: 63 (4 ULg) Impact des tiques sur la croissance des agneaux DjallonkéHounzangbe, M. S.; Koutinhouin, G. B.; Linton, E. et alin Annales de Médecine Vétérinaire (2001), 145Detailed reference viewed: 35 (2 ULg) Comparative Pathogenesis of Acute and Latent Infections of Calves with Bovine Herpesvirus Types 1 and 5Meyer, Gilles; Lemaire, Mylène; Ros, C. et alin Archives of Virology (2001), 146(4), 633-52This study was conducted to compare the pathogenesis of acute and latent infections with closely related bovine herpesvirus types 1 (BHV-1) and 5 (BHV-5) in their natural host. Two groups of eight calves ... [more ▼]This study was conducted to compare the pathogenesis of acute and latent infections with closely related bovine herpesvirus types 1 (BHV-1) and 5 (BHV-5) in their natural host. Two groups of eight calves were inoculated intranasally with BHV-1 or BHV-5. Although BHV-1 and BHV-5 similarly replicate in the nasal mucosa after inoculation, both viruses differ markedly in their ability to cause disease, BHV-5 being responsible of some fatal encephalitis while BHV-1 inducing rhinotracheitis. Virus isolation and immunohistochemistry demonstrated that BHV-5 replicates extensively in neurons of the central nervous system (CNS) and in respiratory cells of lungs, tracheal and nasal mucosae. Invasion of the CNS likely occurs through the trigeminal and olfactory pathways. Both groups developed cross-neutralising antibodies during this experiment suggesting partial clinical cross-protection afforded by the two infections. Three months after primary infection, experimental reactivation showed that BHV-5 was able to establish latency in the trigeminal ganglia but also the CNS of surviving calves. Moreover, laboratory findings suggested that BHV-5 could also persist in the tracheal and nasal mucosae. These results indicate that, after primary infection, BHV-1 and BHV-5 displayed similar biological features and consequently need to be considered together for the control of BHV-1 infection. [less ▲]Detailed reference viewed: 26 (2 ULg) Productivity Overshadows Temperature In Determining Soil And Ecosystem Respiration Across European ForestsJanssens, Ia.; Lankreijer, H.; Matteucci, G. et alin Global Change Biology (2001), 7(3), Detailed reference viewed: 38 (1 ULg) Stability of strange quark matter in an effective chiral model with scale anomalyJaminon, Martine ; Van den Bossche, Brunoin Nuclear Physics A (2001), 686Stability of strange quark matter is investigated within a chiral model which implements the scale anomaly of QCD. As far as quark confinement is mimicked by a large value of the u-quark mass, the model ... [more ▼]Stability of strange quark matter is investigated within a chiral model which implements the scale anomaly of QCD. As far as quark confinement is mimicked by a large value of the u-quark mass, the model behaves in the chiral limit as a MIT bag model: it yields a stable system composed of quarks surrounded by the vacuum. As soon as finite current quark masses are taken into account, stability is however lost. [less ▲]Detailed reference viewed: 18 (2 ULg) Effet of dietary fat levels on growth, feed efficiency and biochemical compositions of Eurasian perch Perca fluviatilisXu; Fontaine, P.; Mélard, Charles et alin Aquaculture International (2001), 9Detailed reference viewed: 15 (5 ULg) An 'other-race' effect in age estimation from facesDehon, Hedwige ; Brédart, Serge in Perception (2001), 30(9), 1107-1113Previous studies have shown that, in person-recognition tasks, people performance better for gaces belonging to their own race than for those belonging to another race. Recently, however, this 'other-race ... [more ▼]Previous studies have shown that, in person-recognition tasks, people performance better for gaces belonging to their own race than for those belonging to another race. Recently, however, this 'other-race' effect has also been found in a sex-discrimination task (O'Toole et al, 1996, Perception 25, 669-676). In the present study, we investigated wheter this finding extends to age perception. Caucasian and African participants were asked to estimate the age of Caucasian and African faces. The main result of this experiment was a significant 'race of subject' x 'race of face' interaction showing that Caucasian participants performed better at evaluating Caucasian faces than African faces. However, African participants performed equally with both type of faces. This result is explained by the Africans' time of residence in Belgium. This implication of this 'older-race' effect for age estimation is discussed with respect to eyewitness reports. [less ▲]Detailed reference viewed: 102 (26 ULg) Outcome is not improved by the use of alternating chemotherapy in elderly patients with aggressive lymphomaBosly, André; Lepage, Eric; Coiffier, Bertrand et alin Hematology Journal : The Official Journal of the European Haematology Association (2001), 2Detailed reference viewed: 12 (0 ULg) Flow rate quality of new flat fan nozzlesHuyghebaert, Bruno; Debouche, Charles ; Mostade, Olivierin Transactions of the ASAE (2001), 44(4), 769-773Manufacturers of spraying nozzles have established manufacturing tolerances to guarantee the quality of their products. They control, among other things, the new nozzles’ flow rate by comparison with the ... [more ▼]Manufacturers of spraying nozzles have established manufacturing tolerances to guarantee the quality of their products. They control, among other things, the new nozzles’ flow rate by comparison with the nominal flow rate. When the deviation exceeds a set limit, the nozzles are rejected. A survey carried out among three manufacturers made it possible to determine the manufacturing tolerances and limits that manufacturers impose upon themselves. The flow rates of 1565 new nozzles collected on the market from these manufacturers were measured on a device developed for this study. Different statistical tests assessed the performances and characteristics of the products. The quality standards announced by the manufacturers were not checked for every nozzle. On average, 20% of the new nozzles exceeded the manufacturing tolerances. The average flow rate of the nozzle sets equalled the nominal flow rate. In practice, the probability distribution of the flow rate of new nozzles should be normal. The dispersion of the new nozzle flow rates was slightly higher than the theoretical one. The quality of the products differed from one manufacturer to another. [less ▲]Detailed reference viewed: 64 (5 ULg) Effects of allelochemicals from first (Brassicaceae) and second (Myzus persicae and Brevicoryne brassicae) trophic levels on Adalia bipunctataFrancis, Frédéric ; Lognay, Georges ; Wathelet, Jean-Paul et alin Journal of Chemical Ecology (2001), 27(2), 243-256Three Brassicaceae species, Brassica napus (low glucosinolate content), Brassica nigra (including sinigrin), and Sinapis alba (including sinalbin) were used as host plants for two aphid species: the ... [more ▼]Three Brassicaceae species, Brassica napus (low glucosinolate content), Brassica nigra (including sinigrin), and Sinapis alba (including sinalbin) were used as host plants for two aphid species: the generalist Myzus persicae and the specialist Brevicoryne brassicae. Each combination of aphid species and prey host plant was used to Feed the polyphagous ladybird beetle, Adalia bipunctata. Experiments with Brassicaceae species including different amounts and kinds of glucosinolates (GLS) showed increased ladybird larval mortality at higher GLS concentrations. When reared on plants with higher GLS concentrations, the specialist aphid, B. brassicae, was found to be more toxic than M. persicae. Identification of GLS and related degradation products, mainly isothiocyanates (ITC), was investigated in the first two trophic levels, plant and aphid species, by high-performance liquid chromatography and gas chromatography-mass spectrometry, respectively. While only GLS were detected in M. persicae on each Brassicaceae species, high amounts of ITC were identified in B. brassicae samples (allyl-ITC and benzyl-ITC from B. nigra and S. alba, respectively) from all host plants. Biological effects of allelochemicals from plants on predators through aphid prey are discussed in relation to aphid species to emphasize the role of the crop plant in integrated pest management in terms of biological control efficacy. [less ▲]Detailed reference viewed: 43 (7 ULg) Molecular identification of three sympatric species of wood mice (Apodemus sylvaticus, A-flavicollis, A-alpicola) in western Europe (Muridae : Rodentia)Michaux, Johan ; Kinet, Séverine ; Filippucci, M. G. et alin Molecular Ecology Notes (2001), 1(4), 260-263The woodmouse (Apodemus sylvaticus) and yellow-necked fieldmouse (Apodelnus flavicollis) are sympatric and even syntopic in many regions throughout their European range. Their field discrimination on the ... [more ▼]The woodmouse (Apodemus sylvaticus) and yellow-necked fieldmouse (Apodelnus flavicollis) are sympatric and even syntopic in many regions throughout their European range. Their field discrimination on the basis of external characters is a real challenge for many fields of research. The problem is even more complicated in the Alpine chain where they live sympatrically with a third similar species: A. alpicola. A rapid and simple method is proposed to discriminate the three species in processing field-collected biopsies as well as ethanol-preserved museum samples. [less ▲]Detailed reference viewed: 46 (3 ULg) Chemical Recognition of Antioxidants and UV-light Stabilizers on the Surface of Polypropylene : Atomic Force Microscopy with Chemically Modified TipsDuwez, Anne-Sophie ; Poleunis, Claude; Bertrand, Patrick et alin Langmuir (2001), 17We show in this paper that it is possible to locally detect additives on the surface of polypropylene with chemically modified atomic force microscopy (AFM) tips. Gold-coated AFM tips modified with methyl ... [more ▼]We show in this paper that it is possible to locally detect additives on the surface of polypropylene with chemically modified atomic force microscopy (AFM) tips. Gold-coated AFM tips modified with methyl and hydroxyl terminated self-assembled alkanethiol monolayers were used to measure adhesion forces on a process-stabilizing agent (Irgafos 168), an antioxidant (Irganox 1010), and UV-light stabilizers (Tinuvin 770, Dastib 845, Chimassorb 944, and Hostavin N30). Pull-off force measurements carried out on these pure additive films have shown that it is possible to discriminate between antioxidants and UV-light stabilizers. We have evidenced a characteristic fingerprint for each additive, according to the functionality of the tip used and themediumwherein the force measurements are realized (water or nitrogen atmosphere). Similarly we have measured pull-off forces on a melt-pressed polypropylene sample stabilized with Irgafos 168, Irganox 1010, and Tinuvin 770. These adhesion force measurements show that the extreme surface of the polymer is mainly made of a layer of Tinuvin 770. These results have been compared to those obtained from time-of-flight secondary ion mass spectrometry measurements [less ▲]Detailed reference viewed: 34 (0 ULg) À la croisée du temps, de l’aspect et du mode: Le conjonctif en néo-égyptienWinand, Jean in Lingua Aegyptia [= LingAeg] (2001), (9), 293-329Detailed reference viewed: 99 (6 ULg) Application of the accelerated shelf life testing method (ASLT) to study the survival rates of freeze-dried Lactococcus starter culturesAchour, M.; Mtimet, N.; Cornelius, C. et alin Journal of Chemical Technology & Biotechnology (2001), 74Detailed reference viewed: 78 (4 ULg) Info-congres. Prevention pharmacologique de la progression de la diminution de la tolerance au glucose vers le diabete de type 2: effets favorables de la metformine et de l'acarbose.Scheen, André in Revue Médicale de Liège (2001), 56(10), 727-30We report the positive results of two large prospective studies of pharmacological prevention of type 2 diabetes presented at the EASD Congress in Glasgow, September 12, 2001. In the "Diabetes Prevention ... [more ▼]We report the positive results of two large prospective studies of pharmacological prevention of type 2 diabetes presented at the EASD Congress in Glasgow, September 12, 2001. In the "Diabetes Prevention Program", metformin (2 x 850 mg/day), a biguanide compound, reduces the progression from impaired glucose tolerance towards type 2 diabetes by 31% (p < 0.001) while in the "STOP-NIDDM trial", acarbose (3 x 100 mg/day), an alpha-glucosidase inhibitor, diminished it by 24% (p < 0.002). These results are, however, less marked than those obtained with lifestyle modifications including better dietary habits and increased physical exercise (-58% versus control group, p < 0.001). [less ▲]Detailed reference viewed: 15 (0 ULg) On the origin and systematics of the northern African wood mouse (Apodemus sylvaticus) populations: a comparative study of mtDNA restriction patternsLibois, Roland ; Michaux, Johan ; Ramalhinho, M. G. et alin Canadian Journal of Zoology (2001), 79(8), 1503-1511Conflicting hypotheses have been formulated regarding the origin of wood mouse (Apodemus sylvaticus) populations in northern Africa. In this study, the mtDNA restriction patterns of mice (n = 28 ... [more ▼]Conflicting hypotheses have been formulated regarding the origin of wood mouse (Apodemus sylvaticus) populations in northern Africa. In this study, the mtDNA restriction patterns of mice (n = 28) collected in Tunisia and Morocco are compared with those of representatives from southern Europe (n = 102). The neighbour-joining tree confirms the existence of the three lineages previously found in the Mediterranean area: western, Tyrrhenian-Balkan, and Sicilian. The western group is isolated from the two others, with bootstrap values of 89 and 95%. Northern African patterns are included in the western group. Their variability is low, the same pattern being shared by five Tunisian and all Moroccan animals (n = 18), caught either in the north of the country (Cap Spartel) or in the south (Marrakech). This implies that northern African wood mouse populations have a southwestern European origin and that their presence in the region is probably recent, which corresponds to both paleontological data and the hypothesis of anthropogenic introduction. [less ▲]Detailed reference viewed: 54 (1 ULg) The ornithine decarboxylase gene is essential for cell survival during early murine developmentPendeville-Samain, Hélène ; Carpino, Nick; Marine, Jean-Christophe et alin Molecular & Cellular Biology (2001), 21(19), 6549-58Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse ... [more ▼]Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse biological processes, including cell growth, differentiation, transformation, and apoptosis. To explore the physiological function of ODC in mammalian development, we generated mice harboring a disrupted ODC gene. ODC-heterozygous mice were viable, normal, and fertile. Although zygotic ODC is expressed throughout the embryo prior to implantation, loss of ODC did not block normal development to the blastocyst stage. Embryonic day E3.5 ODC-deficient embryos were capable of uterine implantation and induced maternal decidualization yet failed to develop substantially thereafter. Surprisingly, analysis of ODC-deficient blastocysts suggests that loss of ODC does not affect cell growth per se but rather is required for survival of the pluripotent cells of the inner cell mass. Therefore, ODC plays an essential role in murine development, and proper homeostasis of polyamine pools appears to be required for cell survival prior to gastrulation. [less ▲]Detailed reference viewed: 42 (7 ULg) Regard sur une réalité qui se construit: l'autonomie fiscale des communautés et des régions dans le système de financementBourgeois, Marc in Revue Générale de Fiscalité [= RFG] (2001)Detailed reference viewed: 57 (19 ULg) The emerging role of class II histone deacetylases.Fischle, Wolfgang; Kiermer, Véronique; Dequiedt, Franck et alin Biochemistry & Cell Biology (2001), 79(3), 337-48Histone acetylation and deacetylation play essential roles in modifying chromatin structure and regulating gene expression in all eukaryotes. Several histone acetyltransferases have been identified that ... [more ▼]Histone acetylation and deacetylation play essential roles in modifying chromatin structure and regulating gene expression in all eukaryotes. Several histone acetyltransferases have been identified that act as transcriptional coactivators. In contrast, histone deacetylases (HDACs) are part of transcriptional corepressor complexes. Based on their similarity to known yeast factors, the human HDACs are grouped into three classes. Class I HDACs are similar to the yeast transcriptional repressor yRPD3, while class II HDACs are related to yHDA1 and class III HDACs to ySIR2. In this review, we focus on the biology of class II HDACs. These newly discovered enzymes have been implicated in cell differentiation and development, and many molecular details are emerging that shed light on class II HDAC function and regulation. We discuss the biological role of these factors in the context of physiological processes. [less ▲]Detailed reference viewed: 169 (5 ULg) Rt-Pcr-Elosa Tests On Pooled Sample Units For The Detection Of Virus Y In Potato TubersChandelier, Anne; Dubois, Nathalie ; Baelen, Frédéric et alin Journal of Virological Methods (2001), 91(2), 99-108Detailed reference viewed: 18 (2 ULg) On a general decomposition of the error of an approximate stress field in elasticityDebongnie, Jean-François ; Beckers, Pierre in Computer Assisted Mechanics and Engineering Sciences [=CAMES] (2001), 8The errors of finite element approximations are analysed in a general frame, which is completely independent from the way through which the approximate solution was obtained. It is found that the error ... [more ▼]The errors of finite element approximations are analysed in a general frame, which is completely independent from the way through which the approximate solution was obtained. It is found that the error always admits decomposition in two terms, namely the equilibrium error and the compatibility error, which are orthogonal. Each of these admits upper and lower bound that can be computed in a post-processing scheme [less ▲]Detailed reference viewed: 38 (7 ULg) The NETLANDER Ionosphere and Geodesy ExperimentBarriot, Jean-Pierre; Dehant, Véronique; Folkner, W. et alin Advances in Space Research (2001), 28(8), 1237-1249Detailed reference viewed: 27 (3 ULg) Factors affecting hematopoietic recovery after autologous peripheral blood progenitof-cell transplantation in aggressive non-Hodgkin's lymphoma : a prospective study of 123 patientsLangouet, Anne-Marie; Brice, Pauline; Simon, Danielle et alin Hematology Journal : The Official Journal of the European Haematology Association (2001), 2Detailed reference viewed: 25 (0 ULg) Experimental and Theoretical Energy Levels, Transition probabilities and Radiative Lifetimes in Yb IIIBiémont, Emile ; Garnir, Henri-Pierre ; Li, Z. S. et alin Journal of Physics : B Atomic Molecular & Optical Physics (2001), 34Detailed reference viewed: 23 (2 ULg) Crystal Structure of Human Peroxiredoxin 5, a Novel Type of Mammalian Peroxiredoxin at 1.5 Ǻ ResolutionDeclercq, Jean-Paul; Evrard, Christine ; Clippe, André et alin Journal of Molecular Biology (2001), 311The peroxiredoxins define an emerging family of peroxidases able to reduce hydrogen peroxide and alkyl hydroperoxides with the use of reducing equivalents derived from thiol-containing donor molecules ... [more ▼]The peroxiredoxins define an emerging family of peroxidases able to reduce hydrogen peroxide and alkyl hydroperoxides with the use of reducing equivalents derived from thiol-containing donor molecules such as thioredoxin, glutathione, trypanothione and AhpF. Peroxiredoxins have been identified in prokaryotes as well as in eukaryotes. Peroxiredoxin 5 (PRDX5) is a novel type of mammalian thioredoxin peroxidase widely expressed in tissues and located cellularly to mitochondria, peroxisomes and cytosol. Functionally, PRDX5 has been implicated in antioxidant protective mechanisms as well as in signal transduction in cells. We report here the 1.5 Ǻ resolution crystal structure of human PRDX5 in its reduced form. The crystal structure reveals that PRDX5 presents a thioredoxin-like domain. Interestingly, the crystal structure shows also that PRDX5 does not form a dimer like other mammalian members of the peroxiredoxin family. In the reduced form of PRDX5, Cys47 and Cys151 are distant of 13.8 Ǻ although these two cysteine residues are thought to be involved in peroxide reductase activity by forming an intramolecular disul®de intermediate in the oxidized enzyme. These data suggest that the enzyme would necessitate a conformational change to form a disulfide bond between catalytic Cys47 and Cys151 upon oxidation according to proposed peroxide reduction mechanisms. Moreover, the presence of a benzoate ion, a hydroxyl radical scavenger, was noted close to the active-site pocket. The possible role of benzoate in the antioxidant activity of PRDX5 is discussed. [less ▲]Detailed reference viewed: 33 (0 ULg) A nuclear magnetic resonance study of the miconazole-b-cyclodextrin inclusion complex in an acidic medium: determination of the structure and stability constantsPiel, Géraldine ; Llabres, Gabriel ; Evrard, Brigitte et alin STP Pharma Sciences (2001), 11(3), 235-238Detailed reference viewed: 75 (4 ULg) Hepatotoxicity with thiazolidinediones: is it a class effect?Scheen, André in Drug Safety : An International Journal of Medical Toxicology & Drug Experience (2001), 24(12), 873-88Decreased insulin sensitivity plays a major role in various human diseases. particularly type 2 diabetes mellitus, and is associated with a higher risk of atherosclerosis and cardiovascular complications ... [more ▼]Decreased insulin sensitivity plays a major role in various human diseases. particularly type 2 diabetes mellitus, and is associated with a higher risk of atherosclerosis and cardiovascular complications. Thiazolidinediones, more commonly termed glitazones, are the first drugs to specifically target muscular insulin resistance. They have proven efficacy for reducing plasma glucose levels in patients with type 2 diabetes mellitus treated with diet alone, sulphonylureas, metformin or insulin. In addition, they are associated with some improvement of the cardiovascular risk profile. However, troglitazone, the first compound approved by the Food and Drug Administration in the US, proved to be hepatotoxic and was withdrawn from the market after the report of several dozen deaths or cases of severe hepatic failure requiring liver transplantation. It remains unclear whether or not hepatotoxicity is a class effect or is related to unique properties of troglitazone. Rosiglitazone and pioglitazone, two other glitazones, appear to have similar efficacy with regard to blood glucose control in patients with type 2 diabetes mellitus as compared with troglitazone. In controlled clinical trials, the incidence of significant (> or =3 x upper limit of normal) increases in liver enzyme levels (ALT in particular) was similar with rosiglitazone or pioglitazone as compared with placebo, whereas troglitazone was associated with a 3-fold greater incidence. In contrast to the numerous case reports of acute liver failure in patients receiving troglitzone, only a few case reports of hepatotoxicity have been reported in patients treated with rosiglitazone until now, with a causal relationship remaining uncertain. Furthermore, no single case of severe hepatotoxicity has been reported yet with pioglitazone. It should be mentioned that troglitazone, unlike pioglitazone and rosiglitazone, induces the cytochrome P450 isoform 3A4, which is partly responsible for its metabolism, and may be prone to drug interactions. Importantly enough, obesity, insulin resistance and type 2 diabetes mellitus are associated with liver abnormalities, especially non-alcoholic steatohepatitis, independent of any pharmacological treatment. This association obviously complicates the selection of patients who are good candidates for a treatment with glitazones as well as the monitoring of liver tests after initiation of therapy with any thiazolidinedione compound. While regular monitoring of liver enzymes is still recommended and more long term data are desirable, current evidence from clinical trials and postmarketing experience in the US supports the conclusion that rosiglitazone and pioglitazone do not share the hepatotoxic profile of troglitazone. [less ▲]Detailed reference viewed: 34 (1 ULg) Calculated transition probabilities in highly charged Ti-like ionsBiémont, Emile ; Träbert, E.; Zeippen, C. J.in Journal of Physics : B Atomic Molecular & Optical Physics (2001), 34Detailed reference viewed: 12 (3 ULg) A Plea to Bridge the Gap between Antifungals and the Management of OnychomycosisARRESE ESTRADA, Jorge ; Pierard-Franchimont, Claudine ; Pierard, Gérald in American Journal of Clinical Dermatology (2001), 2(5), 281-4Onychomycosis represents a stubborn problem for the clinician facing up to the realities of antifungal treatments. There are obvious discrepancies between data given by in vitro antifungal testings ... [more ▼]Onychomycosis represents a stubborn problem for the clinician facing up to the realities of antifungal treatments. There are obvious discrepancies between data given by in vitro antifungal testings, pharmacodynamics and pharmacokinetics, and those gathered from clinical experience. This critical review is an attempt at bridging the gap between in vitro and in vivo information about oral antifungals that aim to treat onychomycoses. Common sense shows that the in vitro concept of fungicidy cannot be simply extrapolated into clinical practice. Indeed, chlamidoconidia and arthroconidia present in vivo are much more resistant to antifungals than hyphae. Corneofungimetry may be a realistic bioassay in predicting antifungal activity in human infections. Boosting hyphae growth from conidia while taking antifungals is a new and appealing treatment modality that deserves controlled study. [less ▲]Detailed reference viewed: 15 (0 ULg) Expression, purification, crystallization and preliminary X-ray analysis of the native class C beta-lactamase from Enterobacter cloacae 908R and two mutants.Wouters, J.; Charlier, Paulette ; Monnaie, D. et alin Acta Crystallographica Section D-Biological Crystallography (2001), 57(Pt 1), 162-4Crystals have been obtained of the Enterobacter cloacae 908R beta-lactamase and two point mutants by the vapour-diffusion method using similar conditions [pH 9.0, polyethylene glycol (M(r) = 6000) as ... [more ▼]Crystals have been obtained of the Enterobacter cloacae 908R beta-lactamase and two point mutants by the vapour-diffusion method using similar conditions [pH 9.0, polyethylene glycol (M(r) = 6000) as precipitant]. The three crystal forms belong to the orthorhombic space group P2(1)2(1)2, with roughly the same unit-cell parameters; i.e. for the wild-type crystals a = 46.46, b = 82.96, c = 95.31 A. In the best cases, the crystals diffract to about 2.1 A resolution on a rotating-anode X-ray source at room temperature. Co-crystallization experiments of poor substrates with the wild-type protein and the active-site serine mutant (S64C) are planned and should lead to a better understanding of the catalytic mechanism of class C beta-lactamases. [less ▲]Detailed reference viewed: 21 (0 ULg) Thiazolidinediones and liver toxicity.Scheen, André in Diabètes & Métabolism (2001), 27(3), 305-13Thiazolidinediones or glitazones specifically target insulin resistance. They have proven efficacy for reducing plasma glucose levels of type 2 diabetic patients treated with diet alone, sulphonylureas ... [more ▼]Thiazolidinediones or glitazones specifically target insulin resistance. They have proven efficacy for reducing plasma glucose levels of type 2 diabetic patients treated with diet alone, sulphonylureas, metformin or insulin. In addition, they may be associated to some improvement of cardiovascular risk profile. However, troglitazone, the first compound approved by the FDA in the US, proved to be hepatotoxic and was withdrawn from the market after the report of several dozens of deaths or cases of severe hepatic failure requiring liver transplantation. It remains unclear whether or not hepatotoxicity is a class effect or is related to the unique tocopherol side chain of troglitazone. Rosiglitazone and pioglitazone, two other glitazones, appear to have similar efficacy on blood glucose control of type 2 diabetic patients as compared to troglitazone. In controlled clinical trials, the incidence of significant increases in liver enzyme levels (ALT) was similar with rosiglitazone or pioglitazone as compared to placebo, whereas troglitazone was associated with a threefold greater incidence. In contrast to the numerous case reports of acute liver failure in patients receiving troglitzone, only two cases of severe reversible liver failure have been reported in patients treated with rosiglitazone, with a causal relationship remaining uncertain. Furthermore, no single case of severe hepatotoxicity has been reported yet with pioglitazone. While regular monitoring of liver enzymes is still recommended and more long-term data are desirable, current clinical evidence supports the conclusion that rosiglitazone and pioglitazone do not share the hepatotoxic profile of troglitazone. [less ▲]Detailed reference viewed: 486 (2 ULg) Is Aggregation Of Beta-Amyloid Peptides A Mis-Functioning Of A Current Interaction Process?Festy, F.; Lins, Laurence ; Peranzi, G. et alin Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology (2001), 1546(2), 356-64In a previous study, Hughes et al. [Proc. Natl. Acad. Sci. USA 93 (1996) 2065-2070] demonstrated that the amyloid peptide is able to interact with itself in a two-hybrid system and that interaction is ... [more ▼]In a previous study, Hughes et al. [Proc. Natl. Acad. Sci. USA 93 (1996) 2065-2070] demonstrated that the amyloid peptide is able to interact with itself in a two-hybrid system and that interaction is specific. They further supported that the method could be used to define the sequences that might be important in nucleation-dependent aggregation. The sequence of the amyloid peptide can be split into four clusters, two hydrophilic (1-16 and 22-28) and two hydrophobic (17-21 and 29-42). We designed by molecular modeling and tested by the two-hybrid approach, series of mutations spread all over the sequence and changing the distribution of hydrophobicity and/or the spatial hindrance. In the two-hybrid assay, interaction of native Abeta is reproduced. Screening of mutations demonstrates that the C-domain (residues 29-40 (42)), the median domain (residues 17-22) and the N-domain (1-16) are all crucial for interaction. This demonstrates that almost all fragments of the amyloid peptide but a loop (residues 23-28) and the C-term amino acid are important for the native interaction. We support that the folded three-dimensional (3D) structure is the Abeta-Abeta interacting species, that the whole sequence is involved in that 3D fold which has a low secondary structure propensity and a high susceptibility to mutations and thus should have a low stability. The native fold of Abeta could be stabilized in Abeta-Abeta complexes which could in other circumstances facilitate the nucleation event of aggregation that leads to the formation of stable senile plaques. [less ▲]Detailed reference viewed: 12 (0 ULg) Epidémiologie moléculaire de la fièvre aphteuseThiry, Etienne ; Baranowski, Eric; Domingo, E.in Epidémiologie et Santé Animale (2001), 39(59-67), Detailed reference viewed: 25 (3 ULg) Natural radiative lifetimes in Ce IIZhang, Z. G.; Svanberg, S.; Jiang, Z. et alin Physica Scripta (2001), 63Detailed reference viewed: 13 (1 ULg) Rapport sur le “Workshop on the open archive initiative (OAI) and peer review journals in Europe” - Genève (CERN) 22 au 24 mars 2001Jérôme, Simonein Cahiers de la Documentation = Bladen voor Documentatie (2001), (4), 59-63Detailed reference viewed: 32 (7 ULg) Est-il raisonnable de prescrire de l'hormone de croissance aux personnes âgées ?Legros, Jean-Jacques ; Geenen, Vincent ; Delmotte, Philippein Revue Médicale de Liège (2001), 56Detailed reference viewed: 7 (0 ULg) Ethno-agricultural approach to the rural environment in the prevention of Kashin-Beck diseaseMalaisse, François ; Haubruge, Eric ; Mathieu, Françoise et alin International Orthopaedics (2001), 25Detailed reference viewed: 15 (3 ULg) Cardiac surgery in octogenarians: who, when and how?Pierard, Luc in European heart journal (2001), 22(14), 1159-61Detailed reference viewed: 18 (0 ULg) L'élevage du "mouton de case" : aspects techniques, socio-économiques et perspectives d'amélioration au Yatenga (Burkina Faso)Hamidou, B.; Ilboudo, J.-B.; Ouedraogo, M. et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2001), 5(4), 201-208Detailed reference viewed: 122 (11 ULg) Absence of protective effect of oral insulin on residual ß-cell function in type 1 diabetesGeenen, Vincent in International Diabetes Monitor (2001), 13Detailed reference viewed: 13 (1 ULg) De l'"Etat social actif" à la politique belge de l'emploiMatagne, Geoffroy in Courrier Hebdomadaire du CRISP (2001), 1737-1738Detailed reference viewed: 205 (32 ULg) Richard Caddel and Peter Quartermain, eds, Other: British and Irish Poetry Since 1970Delville, Michel in Verse (2001), 17Detailed reference viewed: 14 (0 ULg) The neural substrate of orientation working memoryCornette, Luc; Dupont, Patrick; Salmon, Eric et alin Journal of Cognitive Neuroscience (2001), 13(6), 813-828We have used positron emission tomography (PET) to identify the neural substrate of two major cognitive components of working memory (WM), maintenance and manipulation of a single elementary visual ... [more ▼]We have used positron emission tomography (PET) to identify the neural substrate of two major cognitive components of working memory (WM), maintenance and manipulation of a single elementary visual attribute, i.e., the orientation of a grating presented in central vision. This approach allowed us to equate difficulty across tasks and prevented subjects from using verbal strategies or vestibular cues. Maintenance of orientations involved a distributed fronto-parietal network, that is, left and right lateral superior frontal sulcus (SFSl), bilateral ventrolateral prefrontal cortex (VLPFC), bilateral precuneus, and right superior parietal lobe (SPL). A more medial superior frontal sulcus region (SFSm) was identified as being instrumental in the manipulative operation of updating orientations retained in the WM. Functional connectivity analysis revealed that orientation WM relies on a coordinated interaction between frontal and parietal regions. In general, the current findings confirm the distinction between maintenance and manipulative processes, highlight the functional heterogeneity in the prefrontal cortex (PFC), and suggest a more dynamic view of WM as a process requiring the coordinated interaction of anatomically distinct brain areas. [less ▲]Detailed reference viewed: 45 (0 ULg) About the relationship between the kallikrein-kinin system and insulinDamas, Jacques ; Liégeois, Jean-François in Current Topics in Peptide and Protein Research (2001), 4Detailed reference viewed: 17 (2 ULg) la fièvre aphteuse : rappels épidémiologiques et cliniquesThiry, Etienne in Point Vétérinaire (2001), 32Detailed reference viewed: 19 (2 ULg) Une révision critique de la distribution de Tortula inermis en BelgiqueVanderpoorten, Alain ; Stieperaere, H.; Sotiaux, André in Dumortiera (2001), 77Detailed reference viewed: 24 (3 ULg) HST and ground-based observations of the gravitational lens system Q1009-0252 A & BClaeskens, Jean-François ; Khmil, S. V.; Lee, Dong Wook et alin Astronomy and Astrophysics (2001), 367In this paper, we propose a critical study of direct images and spectra obtained for the doubly imaged QSO Q1009-0252 A & B (=LBQS1009-0252 A & B). First, we report new observations with the WFPC2 onboard ... [more ▼]In this paper, we propose a critical study of direct images and spectra obtained for the doubly imaged QSO Q1009-0252 A & B (=LBQS1009-0252 A & B). First, we report new observations with the WFPC2 onboard the Hubble Space Telescope (HST), in which the lensing galaxy is very clearly detected. We combine these with existing NICMOS observations in order to characterize the nature and redshift of the lens. Our HST observations are also fitted with simple analytical lens models; estimates expected for the time delay and M/L of the lensing galaxy are derived. Secondly, new and existing ground-based observations are used in order to establish the first multicolour lightcurves of the lensed components. Although the time resolution is low, flux variability is detected for both components. Finally, ground-based spectroscopic observations published by Surdej et al. (1993) are re-processed with a new method designed to extract spectra with small angular separations. The final spectra are analysed on the basis of a simple model including macrolensing and microlensing amplifications and dust extinction. Based on observations collected at the European Southern Observatory (La Silla, Chile) and with the Hubble Space Telescope. [less ▲]Detailed reference viewed: 30 (4 ULg) Serum soluble transferrin receptor concentration is an accurate estimate of the mass of tissue receptors.R'Zik, Samir ; Beguin, Yves in Experimental hematology (2001), 29(6), 677-85OBJECTIVE: Serum levels of the soluble transferrin receptor (sTfR) vary depending on the erythropoietic activity and iron status. In vitro, sTfR shed in the incubation medium correlates well with cellular ... [more ▼]OBJECTIVE: Serum levels of the soluble transferrin receptor (sTfR) vary depending on the erythropoietic activity and iron status. In vitro, sTfR shed in the incubation medium correlates well with cellular TfR, but this relationship has never been established in vivo. To determine the value of serum sTfR as a quantitative marker of the body mass of tissue TfR, we designed experiments to examine the correlation between serum sTfR and tissue TfR in rats with various degrees of erythropoietic activity or iron status. MATERIALS AND METHODS: We studied changes in erythropoietic activity in normal rats as well as in animals experiencing hemolysis, phlebotomy-induced iron deficiency, transfusion- or thiamphenicol-induced erythroid aplasia, or inflammation. At the end of follow-up, ferrokinetic studies were performed and animals were sacrificed. Organs were isolated and homogenized to determine the total mass of tissue TfR from the sum of tissue solubilized TfR in the bone marrow, spleen, liver, and blood cells (direct method). An indirect method was developed to derive the corporeal mass of tissue TfR from a representative marrow sample. RESULTS: As expected, serum sTfR and total mass of tissue TfR varied as a function of iron status and erythropoiesis. Relative erythroid expansion in the spleen was greater than in the bone marrow. With the exception of phlebotomized animals, the indirect method correlated very well with direct measurements of the total mass of tissue TfR (r = 0.97, p < 0.0001). There was a close relationship between the total mass of tissue TfR and the total mass of serum sTfR (r = 0.79, p < 0.0001). Serum sTfR represented approximately 5-6% of the total mass of tissue TfR in most experimental situations, but this ratio was twice as high during iron-restricted erythropoiesis. In addition, the ratio could be higher or lower in nonsteady-state situations, because changes in tissue TfR occurred faster than those of serum sTfR. CONCLUSIONS: Serum sTfR represents a constant proportion of the total mass of tissue TfR over a wide range of erythropoietic activity. However, iron deficiency results in a higher proportion of serum sTfR, and the pace of change in serum sTfR levels is slower than that of tissue TfR mass. [less ▲]Detailed reference viewed: 150 (7 ULg) Il «Fierabraccia» comense fra preziosità umanistiche e antico dialetto lombardo.Moreno, Paola in Moyen Age (Le) (2001)Detailed reference viewed: 28 (0 ULg) Quel aplostome à guidon chromé au fond de la cour ? De la mauvaise influence des thèses logiciennes sur la définition linguistique de l’autonymieBadir, Sémir in Le français moderne (2001), LXIX(1), 49-57Detailed reference viewed: 26 (0 ULg) La métallurgie ancienne en "Terre de Durbuy" : Utilisation des macroscories en dynamique fluvialeHoubrechts, Geoffrey ; Petit, François in Bulletin de la Société Géographique de Liège (2001), 40Avant d’utiliser les scories métallurgiques comme traceur et indicateur de la compétence de l’Aisne à différents endroits de son cours, nous avons relevé les différents atouts qui ont favorisé le ... [more ▼]Avant d’utiliser les scories métallurgiques comme traceur et indicateur de la compétence de l’Aisne à différents endroits de son cours, nous avons relevé les différents atouts qui ont favorisé le développement de la sidérurgie dans la « Terre de Durbuy » et nous avons étudié l’évolution des techniques sidérurgiques afin de mieux comprendre la genèse des scories. Dans cet article, nous étudions plus particulièrement l’évolution longitudinale de la taille des scories dans l’Aisne, entre Blier et Bomal où elle se jette dans l’Ourthe. Vu la trop grande proximité des sites de rejets, nous n’avons pu proposer qu’une vitesse minimum d’avancée de la charge de fond ; les scories prélevées nous ont cependant renseignés sur les variations de puissances spécifiques dans les différents tronçons de la rivière. [less ▲]Detailed reference viewed: 110 (21 ULg) N content of phloem and xylem exudates during the transition to flowering in Sinapis alba and Arabidopsis thalianaCorbesier, Laurent; Havelange, Andrée ; Lejeune, Pierre et alin Plant, Cell & Environment (2001), 24The involvement of nitrogenous substances in the transition to flowering was investigated in Sinapis alba and Arabidopsis thaliana (Columbia). Both species grown in short days (SD) are induced to flower ... [more ▼]The involvement of nitrogenous substances in the transition to flowering was investigated in Sinapis alba and Arabidopsis thaliana (Columbia). Both species grown in short days (SD) are induced to flower by one long day (LD). In S. alba, the phloem sap (leaf and apical exudates) and the xylem sap (root exudate) were analysed in LD versus SD. In A. thaliana, only the leaf exudate could be analysed but an alternative system for inducing flowering without day-length extension was used: the displaced SD (DSD). Significant results are: (i) in both species, the leaf exudate was enriched in Gln during the inductive LD, at a time compatible with export of the floral stimulus; (ii) in S. alba, the root export of amino acids decreased in LD, whereas the nitrate remained unchanged - thus the extra-Gln found in the leaf exudate should originate from the leaves; (iii) extra-Gln was also found very early in the apical exudate of S. alba in LD, together with more Glu; (iv) in A. thaliana induced by one DSD, the leaf export of Asn increased sharply, instead of Gln in LD. This agrees with Asn prevalence in C-limited plants. The putative role of amino acids in the transition to flowering is discussed. [less ▲]Detailed reference viewed: 73 (2 ULg) La gestion des données dans le système SAS sous Windows v6.12Fonton, N. H.; Claustriaux, Jean-Jacques in Notes de biométrie et d'informatique (2001), 1The management of data is one of the major difficulties of the users in the SAS system. The note presents the procedures of data management after a brief summary on the organization and creation of data ... [more ▼]The management of data is one of the major difficulties of the users in the SAS system. The note presents the procedures of data management after a brief summary on the organization and creation of data. Some procedures for statistics analysis are also presented. [less ▲]Detailed reference viewed: 21 (3 ULg) Propofol anesthesia and cerebral blood flow changes elicited by vibrotactile stimulation: a positron emission tomography study.Bonhomme, Vincent ; Fiset, P.; Meuret, P. et alin Journal of Neurophysiology (2001), 85(3), 1299-308We investigated the effects of the general anesthetic agent propofol on cerebral structures involved in the processing of vibrotactile information. Using positron emission tomography (PET) and the H(2)(15 ... [more ▼]We investigated the effects of the general anesthetic agent propofol on cerebral structures involved in the processing of vibrotactile information. Using positron emission tomography (PET) and the H(2)(15)O bolus technique, we measured regional distribution of cerebral blood flow (CBF) in eight healthy human volunteers. They were scanned under five different levels of propofol anesthesia. Using a computer-controlled infusion, the following plasma levels of propofol were targeted: Level W (Waking, 0 microg/ml), Level 1 (0.5 microg/ml), Level 2 (1.5 microg/ml), Level 3 (3.5 microg/ml), and Level R (Recovery). At each level of anesthesia, two 3-min scans were acquired with vibrotactile stimulation of the right forearm either on or off. The level of consciousness was evaluated before each scan by the response of the subject to a verbal command. At Level W, all volunteers were fully awake. They reported being slightly drowsy at Level 1, they had a slurred speech and slow response at Level 2, and they were not responding at all at Level 3. The following variations in regional CBF (rCBF) were observed. During the waking state (Level W), vibrotactile stimulation induced a significant rCBF increase in the left thalamus and in several cortical regions, including the left primary somatosensory cortex and the left and right secondary somatosensory cortex. During anesthesia, propofol reduced in a dose-dependent manner rCBF in the thalamus as well as in a number of visual, parietal, and prefrontal cortical regions. At Level 1 through 3, propofol also suppressed vibration-induced increases in rCBF in the primary and secondary somatosensory cortex, whereas the thalamic rCBF response was abolished only at Level 3, when volunteers lost consciousness. We conclude that propofol interferes with the processing of vibrotactile information first at the level of the cortex before attenuating its transfer through the thalamus. [less ▲]Detailed reference viewed: 14 (2 ULg) Saisie-arrêt: mainlevée et consolidation d'une mesure erronément fondée sur un titre privé, note sous Cass. (1ere ch.), 26 oct. 2000Georges, Frédéric in Actualités du Droit (2001)Detailed reference viewed: 63 (2 ULg) The role of the Technical Barrier to Trade Agreement in the development of transparencyMunoz, Rodolphe in Cambridge Yearbook of European Legal Studies (2001), 4Cet article vise à donner une explication générale du fonctionnement de l'accord OTC. Il s'attarde plus particulièrement sur les aspects concernant le contrôles des barrières techniques au commerce. En ... [more ▼]Cet article vise à donner une explication générale du fonctionnement de l'accord OTC. Il s'attarde plus particulièrement sur les aspects concernant le contrôles des barrières techniques au commerce. En effet, celles-ci sont aujourd'hui les plus entraventes pour les entreprises. [less ▲]Detailed reference viewed: 41 (0 ULg) Episphalosomic Syndrome : A Mca Syndrome Ressembling Fanconi Anemia, with Increased Baseline Level of Chromosome Breaks but No Hypersensivity to ClastogensVerloes, Alain ; JAMAR, Mauricette ; Dideberg, Vinciane et alin Annales de Génétique (2001), 44(2, Apr-Jun), 59-62We describe a child with facial dysmorphism (trigonocephaly, epicanthus, upturned nose, small ears), thumb hypoplasia, micropenis, jejunal atresia and moderate mental retardation with dysphasia ... [more ▼]We describe a child with facial dysmorphism (trigonocephaly, epicanthus, upturned nose, small ears), thumb hypoplasia, micropenis, jejunal atresia and moderate mental retardation with dysphasia. Cytogenetic workup revealed high spontaneous level of chromosomal aberrations (without specific pattern and no quadriradial figures) and borderline to absent hypersensitivity to mitomycin C, making a diagnosis of Fanconi anemia unlikely. The child described here shares similarities with a small number of previous reports. We suggest to refer to this entity as episphalosomic syndrome. Episphalosomic syndrome shows some clinical overlap with Fanconi anemia, but lacks its cytogenetic hallmark. The hematological complications of Fanconi anemia have not been reported in this entity. [less ▲]Detailed reference viewed: 14 (2 ULg) Sensor arrays : an inspired idea or an objective measurement of environmental odours ?Stuetz, R. M.; Nicolas, Jacques in Water Science & Technology (2001), 44(9), 53-58The measure of annoyance odours from sewage treatment, landfill and agricultural practise has become highly significant in the control and prevention of odorous emissions from existing facilities and is ... [more ▼]The measure of annoyance odours from sewage treatment, landfill and agricultural practise has become highly significant in the control and prevention of odorous emissions from existing facilities and is crucial for new planning applications. Current methods (such as GC-MS analysis, H2S and NH3 measurements) provide an accurate description of chemical compositions or act as surrogates for odour strength, but tell us very little about the perceived effect, whereas olfactometry gives the right human response but is very subjectivity and expensive. The use of non-specific sensor arrays may offer an objective and on-line instrument for assessing olfactive annoyance. Results have shown that sensor array systems can discriminate between different odour sources (wastewater, livestock and landfill). The response patterns from these sources can be significantly different and that the intensity of sensor responses is proportional to the concentration of the volatiles. The correlation of the sensors responses against odour strengths have also shown that reasonable fits can be obtained for a range of odour concentrations (100 - 800,000 ou/m3). However, the influence of environmental fluctuations (humidity and temperature) on sensor baselines still remains an obstacle, as well as the need for periodic calibration of the sensory system and the choice of a suitable gas for different environmental odours. [less ▲]Detailed reference viewed: 33 (3 ULg) Effects of 8-epi-Pgf2alpha on isolated bronchial smooth muscle of healthy and heaves-affected horsesKirschvink, Nathalie; Art, Tatiana ; Lekeux, Pierre et alin Journal of Veterinary Pharmacology & Therapeutics (2001), 24(3), 215-2218-Epi-PGF2alpha, a prostaglandin-like compound generated by oxidative stress, has been shown to be an in vitro bronchoconstrictor in airways from healthy laboratory animals and healthy humans, but it has ... [more ▼]8-Epi-PGF2alpha, a prostaglandin-like compound generated by oxidative stress, has been shown to be an in vitro bronchoconstrictor in airways from healthy laboratory animals and healthy humans, but it has never been studied in diseased airways. Here, the bronchoconstrictive capacity of 8-epi-PGF2alpha on isolated bronchial rings (BR) of healthy and heaves-affected horses was evaluated by comparing the maximal effect and the potency of 8-epi-PGF2alpha to those of (1) acetylcholine (ACh), (2) its stereoisomer PGF2alpha and (3) its synthetic receptor agonist, U46619. Furthermore, the potential capacity of 8-epi-PGF2alpha to enhance the cholinergic (ACh) responsiveness of bronchial smooth muscle was investigated. 8-Epi-PGF2alpha contracted BR with a rank order of efficacy of Ach > U44619 > PGF2alpha > 8-epi-PGF2alpha in both healthy and heaves-affected horses. The contractile maximal response elicited by 8-epi-PGF2alpha was significantly smaller than that elicited by the other drugs, but was significantly higher in BR from heaves-affected horses than in those sampled in healthy horses, whilst pD2 values were similar. A subthreshold concentration of 8-epi-PGF2alpha (10-7 M) did not induce in vitro cholinergic hyper-responsiveness in BR of either healthy or heaves-affected horses. In conclusion, it has been demonstrated that 8-epi-PGF2alpha is an in vitro bronchoconstrictor of minor importance in healthy horses, but whose efficacy is significantly increased in heaves-affected horses. [less ▲]Detailed reference viewed: 25 (1 ULg) Osmotic pretreatment promotes axillary shooting from cauliflower curd pieces by acting through internal cytokinin level modificationsVandemoortele, Jean-Luc; Kevers, Claire ; Billard, Jean-Pierre et alin Journal of Plant Physiology (2001), 158(2), 221-225In vitro propagation of cauliflower has generally been achieved through axillary shoot proliferation of curd explants on Murashige and Skoog (MS) medium supplemented with an auxin and a cytokinin ... [more ▼]In vitro propagation of cauliflower has generally been achieved through axillary shoot proliferation of curd explants on Murashige and Skoog (MS) medium supplemented with an auxin and a cytokinin. Recently, it has been shown (Vandemoortele 1999) that a soaking in sucrose (-2 MPa for 24 h) of cauliflower curd explants, before culture without any growth regulator, also induced axillary branching. The later procedure avoids the phenomenon of hyperhydricity in the shoots formed. Axillary shooting obtained by the two methods appears to be mediated by modifications of internal cytokinin levels. The osmotic pretreatment did not influence auxin levels, but induced a zeatin and a zeatin riboside levels increase. Curd explants cultured with the usual procedure (on MS medium supplemented with 5 mu mol/L BA and 0.5 mu mol/L NAA) showed a zeatin and zeatin riboside levels increase of the same magnitude and a higher one for isopentenyl adenine and isopentenyl adenosine. The modification of the cytokinin status in the curd explants subjected to a short osmotic pretreatment thus should be less favourable for hyperhydricity. [less ▲]Detailed reference viewed: 33 (1 ULg) Faut-il bannir l’épicéa au nom de la gestion durable ?Claessens, Hugues in Forêt Wallonne (2001), 49-50L'épicéa (Picea abies (L.) Karst.), introduit en 1810 dans la sylviculture belge, est devenu en un siècle la première essence du pays, couvrant près de 200 000 ha et participant largement au développement ... [more ▼]L'épicéa (Picea abies (L.) Karst.), introduit en 1810 dans la sylviculture belge, est devenu en un siècle la première essence du pays, couvrant près de 200 000 ha et participant largement au développement socio-économique des régions rurales du pays et en particulier de l'Ardenne. Mais pour des raisons liées à la mauvaise décomposition de sa fane et à son ombrage, sa culture en futaie pure équienne dense remplit mal les fonctions écologiques de la forêt. Dans toute l'Europe occidentale, confrontée à ce même problème, naît alors une polémique entre les milieux écologistes et les sylviculteurs de l'épicéa : la culture de l'épicéa peut-elle s'envisager dans le cadre de la gestion durable? Dans ce contexte, cette réflexion s'appuie sur les études scientifiques de l'impact de la pessière sur l'environnement ainsi que sur les recherches en matière de sylvicultures alternatives pour montrer qu'une sylviculture raisonnée de l'épicéa, dans les conditions qui lui conviennent, est compatible avec la gestion durable, mais aura probablement comme conséquence une diminution de la surface de la pessière. Afin d'ancrer, notre réflexion sur des études concrètes, notre démonstration fait référence à la pessière belge. [less ▲]Detailed reference viewed: 69 (18 ULg) Infections virales humaines d'origine alimentaireScipioni, Alexandra ; Daube, Georges ; Thiry, Etienne in Point Vétérinaire (2001), 218Detailed reference viewed: 42 (3 ULg) Investigation of defect levels in Mg-doped GaN Schottky structures by thermal admittance spectroscopyNguyen, Ngoc Duy ; Germain, Marianne; Schmeits, Marcel et alin Physica Status Solidi B. Basic Research (2001), 228Schottky structures based on Mg-doped GaN layers grown by metalorganic chemical vapor deposition (MOCVD) on sapphire substrate are studied by thermal admittance spectroscopy from 90 K to room temperature ... [more ▼]Schottky structures based on Mg-doped GaN layers grown by metalorganic chemical vapor deposition (MOCVD) on sapphire substrate are studied by thermal admittance spectroscopy from 90 K to room temperature. Evidence of two impurity levels results from the analysis of the observed peaks in the conductance curves, whose positions and strengths are temperature dependent. The experimental results are analyzed within a detailed theoretical study of the steady-state and small-signal electrical characteristics of the structure. Numerical simulations are based on the solution of the basic semiconductor equations for the structure consisting of two Schottky diodes connected back-to-back by a conduction channel formed by the GaN layer. [less ▲]Detailed reference viewed: 45 (8 ULg) Tibère, les cultes étrangers et les astrologues (Suétone, Vie de Tibère, 36)Rochette, Bruno in Etudes Classiques (Namur, Belgium) (2001), 69Detailed reference viewed: 96 (0 ULg) Secret professionnel, confidentialité et juriste d'entreprise : la nouvelle donneThirion, Nicolas ; Benoit-Moury, Annein Journal des Tribunaux (2001)Detailed reference viewed: 78 (3 ULg) Are hyperhydric shoots of Prunus avium L. energy deficient?Franck, Thierry ; Gaspar, Thomas ; Kevers, Claire et alin Plant Science (2001), 160(6), 1145-1151The content of oxidized and reduced pyridine nucleotides and some enzymatic activities of the oxidative pentose phosphate and glycolytic pathways were compared in normal (NS, growing on agar) and ... [more ▼]The content of oxidized and reduced pyridine nucleotides and some enzymatic activities of the oxidative pentose phosphate and glycolytic pathways were compared in normal (NS, growing on agar) and hyperhydric (HS, growing on gelrite) shoots of Prunus avium L. after 4 weeks of in vitro culture. The chlorophyll fluorescence from leaves and the redox capacity or the plasma membrane (reduction of exogenously added ferricyanide) of both types of shoots were recorded. The pool of oxidized and reduced pyridine nucleotides was lower in HS th;ln in NS. These results suggested a reduced metabolism of HS in comparison to normal ones. This hypothesis was also supported by other observations. First, chlorophyll fluorescence measurements showed a lower chlorophyll content and a slight reduction of the photosynthetic capacity in HS. Second, the low activity of some enzymes of oxidative pentose phosphate pathway (OPP) and glycolysis indicated a decline of these biochemical pathways in HS with the consequence of a reduced production of chemical energy in the form of NAD(P)H and ATP. Finally, the lower reduction of ferricyanide by I-IS suggested a lower rate of redox reactions at the level of the plasma membrane of these shoots in comparison to NS. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]Detailed reference viewed: 43 (4 ULg) A simple clinical tool to identify Asian women with osteoporosisLou, SQ; Koh, L; Yang, BY et alin Journal of Rheumatology (2001), 28(S63), 26Detailed reference viewed: 6 (1 ULg) El lenguaje de las personas con sindrome de DownRondal, Jean-Adolphe ; Comblain, Annick in Revista Sindrome de Down (2001), 18(68), 18-28Detailed reference viewed: 160 (0 ULg) Compte rendu de J.-Ch. PICARD, Evêques, saints et cités en Italie, Rome, 1998George, Philippe in Moyen Age (Le) (2001)Detailed reference viewed: 22 (0 ULg) A propos du remplage de la verrière d'Esther.Morard, Thomas in Arte Cristiana (2001), 89(802), 23-30Detailed reference viewed: 22 (7 ULg) Les tourbières analysées en profondeur par le radar de subsurface.Wastiaux, C; Halleux, L; Schumacker, R et alin Hautes Fagnes (2001), 243Detailed reference viewed: 25 (2 ULg) Large-Scale Phenotypic Analysis Reveals Identical Contributions To Cell Functions Of Known And Unknown Yeast GenesBianchi, Mm.; Ngo, S.; Vandenbol, Micheline et alin Yeast (2001), 18(15), Detailed reference viewed: 12 (0 ULg) Radiation therapy alone or combined surgery and radiation therapy in squamous-cell carcinoma of the penis?Zouhair, A; COUCKE, Philippe ; Jeanneret, W et alin European Journal of Cancer (2001), 37Abstract To assess the prognostic factors and the outcome in patients with squamous-cell carcinoma of the penis, a retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of ... [more ▼]Abstract To assess the prognostic factors and the outcome in patients with squamous-cell carcinoma of the penis, a retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of the penis, treated between 1962 and 1994, was performed. The median age was 59 years (range: 35±76 years). According to the International Union Against Cancer (UICC) 1997 classi®cation, there were 12 (29%) T1, 24 (59%) T2, 4 (10%) T3 and 1 TX (2%) tumours. The N-classi®cation was distributed as follows: 29 (71%) patients with N0, 8 (20%) with N1, 3 (7%) with N2 and 1 (2%) with N3. Forty-four per cent (n=18) of the patients underwent surgery: partial penectomy with (n=4) or without (n=12) lymph node dissection, or total penectomy with (n=1) or without (n=1) lymph node dissection. 23 patients were treated with radiation therapy alone, and all but 4 of the patients who were operated upon received postoperative radiation therapy (n=14). The median follow-up period was 70 months (range 20±331 months). In a median period of 12 months (range 5±139 months), 63% (n=26) of the patients relapsed (local in 18, locoregional in 2, regional in 3 and distant in 3). Local failure (stump in the operated patients, and the tumour bed in those treated with primary radiation therapy) was observed in 4 out of 16 (25%) patients treated with partial penectomy postoperative radiotherapy versus 14 out of 23 (61%) treated with primary radiotherapy (P=0.06). 15 (83%) out of 18 local failures were successfully salvaged with surgery. In all patients, 5- and 10-year survival rates were 57% (95% con®dence interval (CI), 41±73%) and 38% (95% CI, 21± 55%), respectively. The 5-year local and locoregional rates were 57% (95% CI, 41±73%) and 48% (95% CI, 32±64%), respectively. In patients treated with primary radiotherapy, 5- and 10-year probabilities of surviving with penis preservation were 36% (95% CI, 22±50%) and 18% (95% CI, 2±34%), respectively. In multivariate analyses, survival was signi®cantly in¯uenced by the N-classi®- cation, and surgery was the only independent factor predicting the locoregional control. We conclude that, in patients with squa- mous-cell carcinoma of the penis, local control is better in patients treated with surgery. However, there seems to be no di erence in terms of survival between patients treated by surgery and those treated by primary radiotherapy salvage surgery, with 39% having organ preservation. [less ▲]Detailed reference viewed: 43 (1 ULg) Carbon balance gradient in European forests: should we doubt 'surprising' results? A reply to Piovesan & AdamsJarvis, P. G.; Dolman, A. J.; Schulze, E. D. et alin Journal of Vegetation Science (2001), 12(1), 145-150This paper responds to the Forum contribution by Piovesan & Adams (2000) who criticized the results obtained by the EUROFLUX network on carbon fluxes of several European forests. The major point of ... [more ▼]This paper responds to the Forum contribution by Piovesan & Adams (2000) who criticized the results obtained by the EUROFLUX network on carbon fluxes of several European forests. The major point of criticism was that the data provided by EUROFLUX are inconsistent with current scientific understanding. It is argued that understanding the terrestrial global carbon cycle requires more than simply restating what was known previously, and that Piovesan & Adams have not been able to show any major conflicts between our findings and ecosystem or atmospheric-transport theories. [less ▲]Detailed reference viewed: 36 (1 ULg) An Early Devonian flora, including Cooksonia from the Paraná Basin (Brazil)Gerrienne, Philippe ; Bergamaschi, S.; Pereira, E. et alin Review of Palaeobotany and Palynology (2001), 116Detailed reference viewed: 44 (10 ULg) TOWNSCOPE II - A computer system to support solar access decision-makingTeller, Jacques ; Azar, Sleiman in International Journal of Solar Energy (2001), 70/3TOWNSCOPE II is a computer system devoted to support solar access decision-making in a sustainable urban design perspective. The software consists of a three-dimensional urban information system coupled ... [more ▼]TOWNSCOPE II is a computer system devoted to support solar access decision-making in a sustainable urban design perspective. The software consists of a three-dimensional urban information system coupled with solar evaluation tools. We’ve paid particular attention to the fact that numerical results interpretation proves to be all but trivial in complex built environments. It is nevertheless a crucial aspect in decision-making, especially for current negotiated urban design practices. Which is why developing visual instruments in order to unveil the geometrical mechanisms lying behind the final results. Various spherical projections were thereby developed, each of them presenting specific advantages and disadvantages for solar access visualisation and/or evaluation purposes. [less ▲]Detailed reference viewed: 278 (25 ULg)