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See detailThymic neuropeptides and T-cell selection
Robert, Françoise; Geenen, Vincent ULg

in Annals of the New York Academy of Sciences (1992), 650

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See detailRaisonnements naturels en hydrodynamique
Blondin, Christiane ULg; Lafontaine, Dominique ULg; Closset, Jean-Louis ULg

in Revue Française de Pédagogie (1992), 100

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See detailUn Coran liégeois
Martin, Aubert ULg; Bauden, Frédéric ULg

in La Vie Wallonne (1992), 56(417-418), 5-20

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See detailLes caractères de l'amitié : Marché du livre et idéologie à Liège vers 1760
Droixhe, Daniel ULg

in Bulletin de la Société Royale Le Vieux-Liège (1992), 256-257

Detailed reference viewed: 27 (2 ULg)
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See detailInheritance and wealth composition
Pestieau, Pierre ULg; Perelman, Sergio ULg

in Journal of Population Economics (1992), (5), 305-318

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French ... [more ▼]

This paper studies the effects of variables pertaining to alternative bequest motives on the composition of households' portofolio. It relies on a 1986 survey on the assets structure of 5600 French households. The main conclusion is that bequest motives indeed influence the composition of households' wealth. However, available data does not allow one to sort out the influence of specific models of inheritance. [less ▲]

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See detailTravail de montage d'ascenseurs et plaintes musculosquelettiques
Collas, Françoise; Mairiaux, Philippe ULg

in Archives des Maladies Professionnelles de Médecine du Travail et de Sécurite Sociale (1992), 53(6), 407-413

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See detailLa communication cryptocrine et la reconnaissance des fonctions neuroendocrines par les cellules T au cours de leur différenciation
Geenen, Vincent ULg; Robert, Françoise; Martens, Henri ULg et al

in Revue Française d'Endocrinologie Clinique, Nutrition, et Métabolisme (La) (1992), 33

Le thymus, organe lymphoïde primaire responsable du développement des lymphocytes T, est le site d'expression de différents peptides appartenant à des familles hormonales distinctes. Le modèle classique ... [more ▼]

Le thymus, organe lymphoïde primaire responsable du développement des lymphocytes T, est le site d'expression de différents peptides appartenant à des familles hormonales distinctes. Le modèle classique de la neurosécrétion établi pour l'axe hypothalamo-neurohypophysaire ne peut cependant s'appliquer à la sécrétion de tels signaux par les cellules épithéliales thymiques. Un nouveau modèle de communication cellulaire, celui de la communication cryptocrine, a été proposé par John W. Funder pour décrire les échanges d'information entre une cellule épithéliale fixe et des cellules mobiles en différenciation à leur contact. Dans le thymus, la communication cryptocrine est étroitement associée à la présentation de la structure moléculaire du Soi par les molécules d'histocompatibilité (CMH) aux lymphocytes T au cours de leur différenciation. Sur la base de nos observations, le modèle du répertoire thymique des autoantigènes neuroendocrines permet de transposer au niveau moléculaire le double rôle physiologique du thymus dans les phénomènes de sélections négative et positive des cellules T, et d'apporter un éclairage nouveau sur les mécanismes responsables de la tolérance immunitaire centrale aux fonctions neuroendocrines. [less ▲]

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See detailDISTINGUISHEDNESS OF WEIGHTED FRECHET SPACES OF CONTINUOUS-FUNCTIONS
Bastin, Françoise ULg

in Proceedings Of The Edinburgh Mathematical Society (1992), 35(Part 2), 271-283

In this paper, we prove that if U is an increasing sequence of strictly positive and continuous functions on a locally compact Hausdorff space X such that VBAR congruent-to VBAR and C(X), then the Frechet ... [more ▼]

In this paper, we prove that if U is an increasing sequence of strictly positive and continuous functions on a locally compact Hausdorff space X such that VBAR congruent-to VBAR and C(X), then the Frechet space CU(X) is distinguished if and only if it satisfies Heinrich's density condition, or equivalently, if and only if the sequence U satisfies condition (H) (cf. e.g.`[1] for the introduction of (H)). As a consequence, the bidual lambda(infinity)(A) of the distinguished Kothe echelon space lambda-0(A) is distinguished if and only if the space lambda-1(A) is distinguished. This gives counterexamples to a problem of Grothendieck in the context of Kothe echelon spaces. [less ▲]

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See detailLutte contre la rage en Belgique: bilan épidémiologique 1991 et stratégie future
Coppens, P.; Brochier, Bernard; Costy, F. et al

in Annales de Médecine Vétérinaire (1992), 136

Two fox vaccination campaigns against rabies were carried out during spring and autumn 1991 in the Belgian contaminated area (10,000 km²). Vaccine-baits containing the vaccinia-rabies recombinant virus ... [more ▼]

Two fox vaccination campaigns against rabies were carried out during spring and autumn 1991 in the Belgian contaminated area (10,000 km²). Vaccine-baits containing the vaccinia-rabies recombinant virus were dropped by air at a mean density of 15 baits/km². In 1991, a drastic decrease in animal rabies cases was observed, as only 29 cases were reported in Belgium. The disease has disappeared from the largest part of the initially contaminated area and, since the beggining of the 2nd trimester 1991, all fox cases were reported exclusively along the French border. If the current epidemiological situation remains the same, the vaccination strategy for 1992 need to be geographically redefined; an immune belt 30 km wide should be created along our borders with France, Grand-Duchy of Luxembourg and Germany. [less ▲]

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See detailEndotoxin-induced microvascular injury in isolated and perfused pig lungs
Urbain, B.; Gustin, Pascal ULg; Ansay, Michel ULg

in Veterinary Research Communications (1992), 16(6), 453-464

The lungs of 13 healthy Landrace piglets were isolated, perfused and maintained in an isogravimetric state under zone III conditions. By applying vascular occlusion methods, the total blood flow ... [more ▼]

The lungs of 13 healthy Landrace piglets were isolated, perfused and maintained in an isogravimetric state under zone III conditions. By applying vascular occlusion methods, the total blood flow resistance (Rt) was partitioned into four components: arterial (Ra), pre- (Ra') and post-capillary (Rv'), and venous (Rv). The capillary filtration coefficient (Kfc) was evaluated using a gravimetric technique. A bolus of 55 micrograms of Escherichia coli endotoxins (LPS) per 100 g of lung was injected into the arterial reservoir of eight lungs, followed by an infusion of LPS at a rate of 55 micrograms per 100 g of lung per hour for 180 min. A bolus of theophylline (85 mg per 100 g of lung weight) was injected into the arterial reservoir after the last determination of the Kfc value. All the parameters were evaluated again when the lungs reached a new steady state. Endotoxin induced a significant increase in Rt from 54.7 +/- 7.0 at zero time to 184.7 +/- 44.2 cmH2O min L-1 (100 g)-1 180 minutes later, which can be ascribed to the increase in Ra' and Rv'. These haemodynamic modifications were related to the increases in the arterial pressure and in the pressure at the distal end of the arterial segment and to the decreases in the pressure at the proximal end of the venous segment and in the blood flow. The capillary pressure and the lung weight remained unchanged. Endotoxin infusion induced an increase in the Kfc value from 0.208 +/- 0.011 (at t = 0) to 0.391 +/- 0.034 ml min-1 (cmH2O)-1 (100 g)-1 (at t = 180). Administration of theophylline significantly reduced Rt,Ra,Ra' and Rv' towards or under the baseline values and also induced a significant increase in the lung weight and in the Kfc value. It was concluded that the endotoxin-induced increase in the total blood flow resistance can be ascribed to a vasospasm occurring at the level of the pre- and post-capillary small vessels and that changes in the permeability of the endothelium greatly contribute to the development of the pulmonary oedema observed in endotoxaemic pigs [less ▲]

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See detailCorrection Method of Secondary Reflection Effects in Measurement of Electrooptic Coefficient in Optically-Active Materials
Lemaire, Philippe ULg; Georges, Marc ULg

in Optics Communications (1992), 91(3-4), 260-266

The propagation of light in linearly birefringent and optically active media, such as Bi12SiO20 crystals (BSO), has been widely studied by several workers. Various measurement methods of the electro-optic ... [more ▼]

The propagation of light in linearly birefringent and optically active media, such as Bi12SiO20 crystals (BSO), has been widely studied by several workers. Various measurement methods of the electro-optic coefficient r41 have been described. One family of those methods consisting in measurement of the light polarization ellipticity after travelling through the crystal has been analysed. Due to the high reflectivity of such crystals, we show that the effect of the secondary reflections can not be neglected. We present the theoretical description and analysis of this effect for one of these methods and we propose a corrective algorithm. [less ▲]

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See detailCulture et démocratie
Martiniello, Marco ULg

in Agenda Interculturel (1992), 106

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See detailEvolution du CA 125 et du SCC dans les cancers gynécologiques
Charlier, Corinne ULg; Plomteux, Guy ULg; Lambrichts, M.

in Focus Diagnostica (1992), 1

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See detailLes adénomes hypophysaires à TSH.
Beckers, Albert ULg; Stevenaert, Achille ULg

in Revue Française d'Endocrinologie Clinique, Nutrition, et Métabolisme (La) (1992), 33(2), 151-156

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See detailLocation of DNA within the nucleolus of rat oocytes during the early stages of follicular growth.
Thiry, Marc ULg; Goessens, Guy ULg

in International Journal of Developmental Biology (1992), 36(1), 139-42

We have investigated the DNA distribution within the rat oocyte nucleolus during the early stages of follicular growth by means of the in situ terminal deoxynucleotidyl transferase method. In the ... [more ▼]

We have investigated the DNA distribution within the rat oocyte nucleolus during the early stages of follicular growth by means of the in situ terminal deoxynucleotidyl transferase method. In the fibrillogranular nucleolus, label is visualized on small clumps of peri- and intranucleolar chromatin. Such labeled clumps are frequently observed inside the interstices surrounding the fibrillar centers. Label is also consistently found in the fibrillar centers whereas the dense fibrillar component and the granular component are devoid of gold particles. These results contradict earlier data but conform with other recent immunocytochemical observations, obtained in nucleoli of a variety of somatic cell types, concerning the correlation between structure and function in the nucleolus. [less ▲]

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See detailThe thermospheric odd nitrogen photochemistry: role of non thermal N(4S) atoms
Shematovich, V.; Bisikalo, D.; Gérard, Jean-Claude ULg

in Geophysical Research Letters (1992), 10

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See detailLes biopesticides en arboriculture fruitiere.
Lepoivre, Philippe ULg; Burgeff, C.; Jijakli, Mohamed ULg et al

in Fruit Belge (1992), 60(440), 242-248

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See detailEditorial : la médecine comportementale : vingt ans après!
Fontaine, Ovide ULg; Etienne, Anne-Marie ULg

in Journal de Thérapie Comportementale et Cognitive (1992), 2(3), 2-3

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See detailLe secret médical dans la législation sociale
Kefer, Fabienne ULg

in Revue de Droit Pénal et de Criminologie (1992)

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See detailRace and Racism in Contemporary Britain
Martiniello, Marco ULg

in Recherches Sociologiques (1992), 3

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See detailAccurate lifetime measurements of the 2p3d 1D° and 2p3d 3P°2 levels in N II with the beam-foil-laser method
Bastin, Thierry ULg; Baudinet-Robinet, Y.; Garnir, Henri-Pierre ULg et al

in Z. Phys. D (1992), 24

We have obtained accurate values for the radiative lifetimes of the 2p 3d 1D° and 2p 3d 3po levels in NII by the cascade-free beam-foil-laser spectroscopy method. Our results are 1r(2p3d 1D°)=0.346_0.012 ... [more ▼]

We have obtained accurate values for the radiative lifetimes of the 2p 3d 1D° and 2p 3d 3po levels in NII by the cascade-free beam-foil-laser spectroscopy method. Our results are 1r(2p3d 1D°)=0.346_0.012 ns and z(2p 3d 3P°)=0.457+0.020 ns. Comparison of these results with experimental and recent theoretical lifetimes reported previously is also made. [less ▲]

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See detailAperçu de la qualité du bois de Chêne rouge d'Amérique
Jourez, Benoît ULg; Leclercq, André

in Bulletin des Recherches Agronomiques de Gembloux (1992), 27(3), 309-325

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See detailUn nouveau timbre amphorique rhodien
Winand, Jean ULg

in Akkadica (1992), 79-80

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See detailRegulation endocrinienne et manipulation de la croissance bovine
Renaville, Robert ULg; Sneyers, M.; Devolder, A. et al

in Cahiers Agricultures (1992), 1(2),

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See detailGBS infection in the perinatal period
Battisti, Oreste ULg

in Journal of Perinatal Medicine (1992), 20

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See detailModélisation mathématique des aquifères
Dassargues, Alain ULg; Monjoie, Albéric ULg

in Bulletin d'Information de l'ANSEAU (1992)

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See detailRapport préliminaire sur la 1ère campagne de fouille à Tell Amarna (Syrie)
Tunca, Önhan ULg

in Akkadica (1992), 79-80

Detailed reference viewed: 3 (1 ULg)
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See detailLymphocyte activation and the family of NF-kappa B transcription factor complexes.
Bours, Vincent ULg; Franzoso, G.; Brown, K. et al

in Current Topics in Microbiology and Immunology (1992), 182

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See detailAlpha-Cheratte: construire ensemble une interculture
Mouvet, Bernadette ULg; Manço, Altay ULg

in Recherche en Education (1992), 8

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See detailRésection hépatique ex situ
Honoré, Pierre ULg; D'Silva, Milbhor; Meurisse, Michel ULg et al

in Médecine & Chirurgie Digestives (1992), 21

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See detailRemotely sensed data contributes to GIS socioeconomic analysis
Donnay, Jean-Paul ULg

in GIS-Europe (1992), 1(10), 38-41

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See detailClinical Neurophysiology Studies in Headache: A Review of Data and Pathophysiological Hints
Schoenen, Jean ULg

in Functional Neurology (1992), 7(3, May-Jun), 191-204

In migraine between attacks EMG studies are normal. Recordings during attacks need to be performed. Temporalis exteroceptive silent period is useful in the differential diagnosis of headaches and sheds ... [more ▼]

In migraine between attacks EMG studies are normal. Recordings during attacks need to be performed. Temporalis exteroceptive silent period is useful in the differential diagnosis of headaches and sheds some light on the pathophysiology of tension-type headache. [less ▲]

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See detailVariability in the bovine GH receptor amino acid sequence
Sneyers, Myriam; Renaville, Robert ULg; Devolder, Anne et al

in Journal of Endocrinological Investigation (1992), 15(suppl 4), 59

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See detailOriginal lithotomy positioning for transperineal extracorporeal shockwave lithotripsy for distal ureteric calculi with Tripter X1.
Andrianne, Robert ULg; Vandeberg, Colette ULg; Bonnet, Pierre ULg et al

in European Urology (1992), 22(2), 134-6

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the ... [more ▼]

Extracorporeal shockwave lithotripsy (ESWL) has been initially designed for stones located in the kidney and the upper ureter. Our lithotripter is no exception. Its components (the table and the orientation of the semi-ellipsoid reflector) are adapted for the treatment of kidney or lumbar ureter stones. However, the elements forming the unit of treatment (the table, the C-arm and the Tripter) can be modified in such a way that focalization of stones of the lower ureter becomes possible through a perineal exposure. The aim is to avoid the pelvic bone shield while a good focalization of the stone is realized. From June 1989 to March 1991, 35 patients were treated for distal ureteric stones by ESWL in this original positioning. [less ▲]

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See detailGLOBOSA: a homeotic gene which interacts with DEFICIENS in the control of Antirrhinum floral organogenesis.
Trobner, W.; Ramirez, L.; Motte, Patrick ULg et al

in EMBO Journal (1992), 11(13), 4693-704

GLOBOSA (GLO) is a homeotic gene whose mutants show sepaloid petals and carpelloid stamens. The similarity of Glo mutants to those of the DEFICIENS (DEFA) gene suggests that the two genes have comparable ... [more ▼]

GLOBOSA (GLO) is a homeotic gene whose mutants show sepaloid petals and carpelloid stamens. The similarity of Glo mutants to those of the DEFICIENS (DEFA) gene suggests that the two genes have comparable functions in floral morphogenesis. The GLO cDNA has been cloned by virtue of its homology to the MADS-box, a conserved DNA-binding domain also contained in the DEFA gene. We have determined the structure of the wild type GLO gene as well as of several glo mutant alleles which contain transposable element insertions responsible for somatic and germinal instability of Glo mutants. Analyses of the temporal and spatial expression patterns of the DEFA and GLO genes during development of wild type flowers and in flowers of various stable and unstable defA and glo alleles indicate independent induction of DEFA and GLO transcription. In contrast, organ-specific up-regulation of the two genes in petals and stamens depends on expression of both DEFA and GLO. In vitro DNA-binding studies were used to demonstrate that the DEFA and GLO proteins specifically bind, as a heterodimer, to motifs in the promoters of both genes. A model is presented which proposes both combinatorial and cross-regulatory interactions between the DEFA and GLO genes during petal and stamen organogenesis in the second and third whorls of the flower. The function of the two genes controlling determinate growth of the floral meristem is also discussed. [less ▲]

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See detailLight scattering by rough surfaces: Electromagnetic model for lighting simulations
Embrechts, Jean-Jacques ULg

in Lighting Research & Technology (1992), 24(4)

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See detailRevision of the structure of strychnofluorine, an alkaloid of Strychnos gossweileri
Quetin-Leclercq, Joëlle; Coune, Claude; Delaude, Clément et al

in Phytochemistry (1992), 31(12), 4347-4349

The structure of strychnofluorine, an indole alkaloid isolated in 1980 from the root bark of Strychnos gossweileri, has been revised. Strychnofluorine proved to be identical with 18 ... [more ▼]

The structure of strychnofluorine, an indole alkaloid isolated in 1980 from the root bark of Strychnos gossweileri, has been revised. Strychnofluorine proved to be identical with 18-hydroxynorfluorocurarine that has been isolated as a minor (contaminated) alkaloid from Strychnos ngouniensis in 1983. [less ▲]

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See detailLight and electron microscopic immunolocalization of bovine pregnancy-associated glycoprotein in the bovine placentome.
Zoli, A.; Demez, Pierre ULg; Beckers, Jean-François ULg et al

in Biology of Reproduction (1992), 46(4), 623-9

A bovine pregnancy-associated glycoprotein (bPAG) of 67 kDa has previously been isolated from bovine fetal cotyledons. The objective of this study was to determine the cytological localization of that ... [more ▼]

A bovine pregnancy-associated glycoprotein (bPAG) of 67 kDa has previously been isolated from bovine fetal cotyledons. The objective of this study was to determine the cytological localization of that protein in the placentomes and possibly the cells responsible for its production. Highly specific antisera raised against pure bPAG were used to demonstrate the cellular localization of the protein in bovine placentomes by light and electron microscopic techniques. Strong immunostaining was observed exclusively in the cytoplasm of large binucleate cells present predominantly in fetal cotyledonary tissue (villi). Some smaller weakly immunostained cells were also present in caruncular epithelium. By ultrastructural immunogold procedures, the protein was detected only within amorphous cytoplasmic granules. Granules of identical size, but weakly labeled, were found on the maternal side. All cells containing labeled granules were binucleate. These results suggest that bPAG is probably synthesized by trophoblast binucleate cells and stored in granules prior to delivery into the maternal circulation after cell migration. [less ▲]

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See detailSuicidal behavior and growth hormone response to apomorphine test.
Pitchot, William ULg; Hansenne, Michel ULg; Moreno, A. G. et al

in Biological Psychiatry (1992), 31(12), 1213-9

Several cerebrospinal fluid (CSF) studies have provided support for a possible role for the dopaminergic system as a biological correlate of suicidal behavior. Indeed, low CSF levels of the dopamine ... [more ▼]

Several cerebrospinal fluid (CSF) studies have provided support for a possible role for the dopaminergic system as a biological correlate of suicidal behavior. Indeed, low CSF levels of the dopamine metabolite homovanillic acid (HVA) have been described in depressed patients with a history of suicide attempts. In this study, we assessed the dopamine receptor sensitivity in relationship to suicidal behavior by measuring growth hormone (GH) response to apomorphine 0.5 mg subcutaneously (sc) in 15 DSM-III-R (APA 1987) major depressive inpatients with a history of suicide attempts, compared to age-matched and gender-matched major depressive inpatients without a history of suicide. Patients with a history of suicidal behavior exhibited a significantly lower GH response to apomorphine than patients who never attempted suicide (t = 3.60, df = 1.28, p = 0.0012). Therefore, these results suggest that a blunted GH response to apomorphine could represent a biological marker of suicidal behavior. [less ▲]

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See detailCombined treatment of liver failure and hepatorenal syndrome with orthotopic liver transplantation
Detroz, Bernard ULg; Honore, Pierre ULg; Monami, B. et al

in Acta Gastro-Enterologica Belgica (1992), 55(4), 350-357

Hepatorenal syndrome (HRS) is a severe complication of liver failure with high mortality. The pathogenesis of this reversible functional renal failure is not yet clearly understood. Diagnosis is based ... [more ▼]

Hepatorenal syndrome (HRS) is a severe complication of liver failure with high mortality. The pathogenesis of this reversible functional renal failure is not yet clearly understood. Diagnosis is based upon the association of clinical and biological criteria. A patient was admitted to our institution for severe liver failure secondary to an exacerbation of cirrhosis, where he developed a fulminant hepatorenal syndrome. Both, the renal and hepatic failure were successfully treated by orthotopic liver transplantation. Special attention was paid to the immunosuppressive treatment with Cyclosporine whose use, we believe, should be delayed until function has partially recovered. [less ▲]

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See detailPsychisme et greffe cardiaque
Triffaux, Jean-Marc ULg; Bertrand, Jean ULg

in Psychologie Médicale (1992)

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See detailBiotechnologies et agriculture: impact et perspectives.
Semal, J.; Lepoivre, Philippe ULg

in Cahiers Agricultures (1992), 1(3),

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See detailEnseigner la géographie à l'Université. Quelques réflexions sur la didactique universitaire
Merenne-Schoumaker, Bernadette ULg

in Acta Geographica Lovaniensia (1992), (33), 67-75

Les recherches en didactique de la géographie se sont multipliées dans les années 1980 mais elles ne concernaient que l'enseignement primaire et secondaire. Le propos de cet article est d'explorer la ... [more ▼]

Les recherches en didactique de la géographie se sont multipliées dans les années 1980 mais elles ne concernaient que l'enseignement primaire et secondaire. Le propos de cet article est d'explorer la didactique dans l'enseignement universitaire en utilisant trois voies majeures: des travaux de pédagogie universitaire; notre propre pratique pédagogique; et nos recherches dans le cadre d'un cours assuré en 3e cycle à l'Université, cours intitulé "Méthodologie de l'enseignement supérieur". [less ▲]

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See detailDirect stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation.
De Groote, D.; Zangerlé, Pierre-François ULg; Gevaert, Y. et al

in Cytokine (1992), 4(3), 239-48

Production of interleukin 1 beta (IL-1 beta), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha), interleukin 2 (IL-2), interferon gamma (IFN-gamma) and granulocyte-macrophage colony ... [more ▼]

Production of interleukin 1 beta (IL-1 beta), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha), interleukin 2 (IL-2), interferon gamma (IFN-gamma) and granulocyte-macrophage colony-stimulating factor (GM-CSF) after stimulation by lipopolysaccharide (LPS) and phytohemagglutinin (PHA) was studied in 1/10 diluted whole blood (WB) culture and in peripheral blood mononuclear cell (PBMC) culture. Cytokines IL-1 beta, TNF-alpha and IL-6 are preferentially stimulated by LPS whereas IL-2, IFN-gamma and GM-CSF are stimulated by PHA. Combination of 5 micrograms/ml PHA and 25 micrograms/ml LPS gave the most reliable production of the six cytokines studied. IL-1 beta, TNF-alpha and IL-6 represent a homogeneous group of early-produced cytokines positively correlated among themselves and with the number of monocytes in the culture (LeuM3). Furthermore, IL-1 beta was negatively correlated with the number of T8 lymphocytes. IL-2, IFN-gamma and GM-CSF represent a group of late-produced cytokines. Kinetics and production levels of IL-6 and GM-CSF are similar in WB and PBMC cultures. In contrast, production levels of TNF-alpha and IFN-gamma are higher in WB than in PBMC whereas production levels of IL-6 and IL-2 are lower in WB than in PBMC. Individual variation in responses to PHA + LPS was always higher in PBMC cultures than in WB cultures. The capacity of cytokine production in relation to the number of mononuclear cells is higher in WB, or in PBMC having the same mononuclear cell concentration as WB, than in conventional cultures of concentrated PBMC (10(6)/ml). Because it mimics the natural environment, diluted WB culture may be the most appropriate milieu in which to study cytokine production in vitro. [less ▲]

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See detailChiral theory of mesons in dense baryonic matter (I)
Jaminon, Martine ULg; Mendez Galain, Ramon; Ripka, Georges et al

in Nuclear Physics A (1992), 537

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See detailC.R. de R. HARVEY, The troubadour Marcabru and Love
Henrard, Nadine ULg

in Moyen Age (Le) (1992), XCVIII

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See detailEvaluation des méthodes de contrôle des anabolisants dans le cadre des décisions européennes
Willemart, Jean-Pierre; Scippo, Marie-Louise ULg; Gaspar, Pol et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailA fog forecasting method in a deeply embanked valley.
Boreux, Jean-Jacques ULg; Guiot, Joël

in Atmospheric Environment, Part A : General Topics (1992), 26(5), 759-764

This paper presents a statistical model used to forecast fog in the Meuse Valley in Belgium. The method is a bootstrap discriminant analysis using eight predictors: river surface temperature, air pressure ... [more ▼]

This paper presents a statistical model used to forecast fog in the Meuse Valley in Belgium. The method is a bootstrap discriminant analysis using eight predictors: river surface temperature, air pressure, air temperature at two elevations, wind speed and relative humidity at the same two locations. These data are measured from November 1989 to April 1990. Tests are done to determine the number of resampling needed for this data set and the optimum projection delay for prediction from the meteorological data. The best results are obtained for the prediction at 0700h UT using meteorological data at 0400 h UT. [less ▲]

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See detailPermeability of the Endothelium and Partitioning of the Pulmonary Blood Flow Resistance in Isolated Perfused Pig Lungs: Effects of Breed and Age
Gustin, Pascal ULg; Urbain, B.; Delaunois, Annie et al

in Veterinary Research Communications (1992), 16(1), 69-82

The right and left lungs of 5 healthy Minipigs and of 13 healthy Landrace piglets were isolated, perfused at constant pressure and maintained in an isogravimetric state under zone III conditions ... [more ▼]

The right and left lungs of 5 healthy Minipigs and of 13 healthy Landrace piglets were isolated, perfused at constant pressure and maintained in an isogravimetric state under zone III conditions (pulmonary venous pressure greater than alveolar pressure). By applying the double, arterial and venous, occlusion technique, the total blood flow resistance (R) was partitioned into four components: arterial (Ra), pre- (Ra') and post-capillary (Rv') and venous (Rv). The capillary filtration coefficient (Kf,c) was evaluated by measuring the weight gained by the lungs when the arterial and venous pressures were suddenly increased. In the youngest Landrace piglets (5 weeks old), there was an uncontrolled vasoconstriction which sometimes prevented perfusion of the lungs and induced a large increase in Rt. These high values of Rt were decreased by tolazoline administration. The values of Rt recorded in older pigs (12-13 weeks old) were lower in Minipigs (33.66 +/- 3.77 cmH2O min L-1 per 100 g of lungs; n = 5) than in Landrace piglets (55.20 +/- 6.18 cmH2O min L-1 per 100 g; n = 5). This breed difference was due to the differences in Ra' and Rv'. The mean values of Kf,c were 0.193 +/- 0.015 and 0.202 +/- 0.029 ml min (cmH2O)-1 per 100 g of the lungs in Minipigs and Landrace piglets respectively. All these parameters were stable for the 3 hours following the equilibrium period. It was concluded that: (1) There is an age-related maturation of the control of the vasomotor tone in porcine lungs. (2) Pulmonary microvascular haemodynamics are influenced by the breed of the pigs. (3) There was no difference in the Kf,c values between both the breeds. (4) A comparison of the values reported for dogs and rabbits with our data shows that the pre- and post-capillary resistances and, to a lesser extent, the arterial and venous resistances are relatively high in pigs [less ▲]

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See detailEtude de l'antibiorésistance de Clostridium perfringens par l'emploi de sondes génétiques.
Daube, Georges ULg; Mainil, Jacques ULg; Limbourg, Bernard et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailLe traitement des prolactinomes par un nouvel agoniste dopaminergique (le CV 205-502) : résultats chez 48 patients.
Beckers, Albert ULg; Ghuysen, A. E.; Abs, R. et al

in Médecine et Hygiène (1992), 50

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See detailClostridium perfringens et pathologies digestives.
Daube, Georges ULg

in Annales de Médecine Vétérinaire (1992), 136

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See detailRésistance au feu des ossatures métalliques
Franssen, Jean-Marc ULg

in Revue Roumaine des Sciences Techniques. Série de Mécanique Appliquée (1992), 37(3), 329-340

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See detailErythropoiesis in multiple myeloma: defective red cell production due to inappropriate erythropoietin production.
Beguin, Yves ULg; Yerna, M.; Loo, Martine et al

in British Journal of Haematology (1992), 82(4), 648-53

We investigated the pathophysiology of erythropoiesis in 62 patients with multiple myeloma and examined whether it would establish a rational basis for the treatment of their anaemia with recombinant ... [more ▼]

We investigated the pathophysiology of erythropoiesis in 62 patients with multiple myeloma and examined whether it would establish a rational basis for the treatment of their anaemia with recombinant human erythropoietin. Erythropoietin (Epo) production was evaluated by serum levels and erythropoiesis was quantitated by serum transferrin receptor (TfR) levels, both assessed relative to the degree of anaemia. Instead of the expected stimulation of erythropoiesis in response to anaemia, haematocrit correlated positively with marrow erythropoietic activity, indicating that the mechanism of anaemia was primarily defective red cell production. Erythropoiesis decreased and anaemia worsened significantly with advancing clinical stage. 25% of the patients had inadequate Epo production and this proportion increased to 50% in stage 3. Inappropriate Epo production was seen in 60% of patients with renal impairment but was also observed in a number of patients with normal renal function. Erythropoiesis correlated strongly with the adequacy of Epo production, particularly in advanced disease. We conclude that most myeloma patients have defective red cell production even in the absence of massive marrow infiltration and that inappropriate Epo production contributes to their anaemia. [less ▲]

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See detailE. Goffman : Les cadres de l'expérience
Melard, François ULg

in Recherches sociologiques (1992), 2

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See detailNew tools for clinical evaluation of erythron function in man.
Cazzola, M.; Beguin, Yves ULg

in British Journal of Haematology (1992), 80(3), 278-84

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See detailEvidence for the expression of growth hormone receptors in human placenta
Frankenne, Francis; Alsat, Eliane; Scippo, Marie-Louise ULg et al

in Biochemical and Biophysical Research Communications (1992), 182(2), 481-486

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See detailNouvelles approches pharmacologiques basées sur les interactions neuro-endocrino-immunitaires
Gueenen, V.; Franchimont, N.; Louis, Edouard ULg et al

in Médecine et Hygiène (1992), 50

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See detailCompte-rendu de Sainte Waudru
George, Philippe ULg

in Moyen Age (Le) (1992)

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See detailAlanine-scanning mutagenesis of human prolactin: importance of the 58-74 region for bioactivity
Goffin, V.; Norman, M.; Martial, Joseph ULg

in Molecular Endocrinology (1992), 6(9), 1381-92

We have generated 10 alanine mutants of human PRL (hPRL), a member of the PRL/GH family, to investigate the involvement of the highly conserved 58-74 region in the biological behavior of the protein. When ... [more ▼]

We have generated 10 alanine mutants of human PRL (hPRL), a member of the PRL/GH family, to investigate the involvement of the highly conserved 58-74 region in the biological behavior of the protein. When treated with polyclonal anti-hPRL antibodies, all mutants were immunologically indistinguishable from the unmodified hPRL, and circular dichroism analyses indicated that their alpha-helix content was similar to that of the unmodified hormone. Mutations C58A, K69A, and, to a lesser extent, P66A affected drastically the ability of hPRL first to bind to the lactogenic receptor and second to stimulate the proliferation of Nb2 lymphoma cells, proving the importance of the 58-74 peptide segment for hPRL bioactivity. Binding affinities of these mutants to the Nb2 lactogenic receptor have been compared to lactogenic binding data previously obtained for several mutants of hGH. The comparison reveals that the residues involved in the biological properties of the two proteins are not at topologically equivalent positions. Hence, we suggest that the binding of these hormones to the lactogenic receptors occurs through a different molecular mechanism having distinct requirements at the residue level. [less ▲]

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See detailToxicité des herbicides chez les animaux domestiques
Delaunois, A.; Gustin, Pascal ULg; Ansay, M.

in Annales de Médecine Vétérinaire (1992), 136

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See detailBâtons percés paléolithiques: décor figuratif, schématique et géométrique
Noiret, Pierre ULg

in Bulletin de l'Association scientifique liégeoise pour la Recherche archéologique (1992), XX

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See detailBurst-firing in dopamine neurons induced by N-methyl-D-aspartate : role of electrogenic sodium pump
Johnson, S.; Seutin, Vincent ULg; North, Alan

in Science (1992), 258

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See detailExtracellular matrix receptors and mouse skin carcinogenesis: altered expression linked to appearance of early markers of tumor progression.
Tennenbaum, T.; Yuspa, S. H.; Grover, A. et al

in Cancer Research (1992), 52(10), 2966-76

Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer ... [more ▼]

Interaction of cells with the basement membrane is important for cell proliferation and differentiation. Disruption of the basement membrane is an early event during progression of benign tumors to cancer. Using the techniques of immunohistochemistry and immunofluorescence, we show that cell-matrix interactions via the cell surface integrin receptors alpha 3 beta 1, alpha 5 beta 1, alpha 6 beta 4, the Mr 67,000 laminin receptor (67LR) laminin-binding protein, and the secreted matrix protein laminin are strictly regulated during differentiation of mouse epidermis. While alpha 6 beta 4 and alpha 5 beta 1 are polarized to the basal surface of basal cells in contact with the basement membrane, alpha 3 beta 1 and the non-integrin 67LR are primarily detected in the cell periphery of suprabasal cells, where cell to cell contacts are found. Sequential changes in expression of matrix receptors occur following multistage carcinogenesis of mouse skin. In an analysis of benign and malignant skin tumors induced by chemical carcinogens or oncogene transduction, we found that alpha 3 beta 1 and alpha 5 beta 1 as well as the non-integrin 67LR are sequentially down-regulated in the progression from benign to malignant, while alpha 6 beta 4 is the predominant receptor expressed in the carcinomas. Tumor expression of alpha 6 beta 4 is not polarized and is dissociated from its colocalized normal partner bullous pemphigoid antigen, which remains restricted to the basement membrane. The changes in matrix receptors are linked to appearance of keratin 13 in suprabasal regions, but always in alpha 6 beta 4 negative cells. The predominance of alpha 6 beta 4 in the proliferating cells during progression is associated with decreased expression of keratin 13 in carcinomas. These results suggest that matrix interactions with its receptors are important determinants of ordered differentiation in normal skin and show characteristic alterations during carcinogenesis that parallel changes in differentiation of the tumors. [less ▲]

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See detailLa fonction respiratoire en tant que facteur potentiellement limitant de la santé, des productions et des performances animales
Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1992), 136

After a description of the various links of the oxygen line and a definition of the notion "limiting factor", this paper describes why the pulmonary function can become a limiting factor in some domestic ... [more ▼]

After a description of the various links of the oxygen line and a definition of the notion "limiting factor", this paper describes why the pulmonary function can become a limiting factor in some domestic animals which have been intensively selected for improved economic or athletic performances. [less ▲]

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See detailL’an un du décret de l’Aide à la jeunesse
Glowacz, Fabienne ULg; Born, Michel ULg

in Revue d’Action Sociale (1992)

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See detailGraphes arithmétiques
Pays, Isabelle ULg

in cahiers mathématiques 39 Montpellier (1992)

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See detailStudy of the antagonism developped by fluorescent Pseudomonas against Pythium spp. using Tn5 and NTG mutants.
Jacques, Ph.; Mistry, C.; Ongena, Marc ULg et al

in Archives Internationales de Physiologie et de Biochimie (1992), 101(B21),

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See detailL'enseignement technique agricole et le défi de l'environnement : passé et futur...
Mougenot, Catherine ULg

in Revue de l'Institut de Sociologie (1992), 1(4), 265-290

Une analyse de l’enseignement agricole technique reposant sur deux fils rouges : l’histoire de l’institution et la nécessité pour celle-ci de prendre en compte les nouvelles perspectives environnementales.

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See detailBilan de cinq années de détection des taurillons infectés de manière persistante par le virus BVD au centre de sélection bovine de Ciney
Waxweiler, S.; Karelle Bui-Thi, L.; Boulanger, D. et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailMetabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy.
Joris, Jean ULg; Cigarini, I.; Legrand, Marc ULg et al

in British Journal of Anaesthesia (1992), 69(4), 341-5

We have compared metabolic and respiratory changes after laparoscopic cholecystectomy (n = 15) with those after open cholecystectomy (n = 15). The durations of postoperative i.v. therapy, fasting and ... [more ▼]

We have compared metabolic and respiratory changes after laparoscopic cholecystectomy (n = 15) with those after open cholecystectomy (n = 15). The durations of postoperative i.v. therapy, fasting and hospital stay were significantly shorter in the laparoscopy group. During the first and second days after operation, analgesic consumption but not pain scores (visual analogue scale) were significantly smaller after laparoscopy, while vital capacity, forced expiratory volume in 1 s, and PaO2 were significantly greater. The metabolic and acute phase responses (glucose, leucocytosis, C-reactive protein) were less after laparoscopy compared with laparotomy. Although plasma cortisol and catecholamine concentrations were not significantly different between the two groups, after surgery interleukin-6 concentrations were less in the laparoscopy group. [less ▲]

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See detailThe interaction between Bovine Leukemia Virus and its target cell.
Burny, Arsène; Kettmann, Richard ULg; Willems, Luc ULg et al

in AIDS Research and Human Retroviruses (1992), 8

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S ... [more ▼]

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S., Portetelle, D., Berte, C., Franssen, J. D., Herion, P., and Burny, A. (1982) Virology 122, 342-352; Voneche, V., Portetelle., D., Kettmann, R., Willems, L., Limbach, K., Paoletti, E., Ruysschaert, J. M., Burny, A., and Brasseur, R. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3810-3814) and suggest that a region encompassing residues 23 and 25 of gp51 is involved in this process (Portetelle, D., Couez, D., Bruck, C., Kettmann, R., Mammerickx, M., Van der Maaten, M., Brasseur, R., and Burny, A. (1989) Virology 169, 27-33; Mamoun, R., Morisson, M., Rebeyrotte, N., Busetta, B., Couez, D., Kettmann, R., Hospital, M., and Guillemain, B. (1990) J. Virol. 64, 4180-4188). X-ray diffraction studies performed on envelope glycoproteins of influenza virus indicate that the NH2-terminal part of the external glycoprotein lies very close to the fusion peptide. The same overall structure seems to exist in human immunodeficiency virus as suggested by site-directed mutagenesis followed by syncytia induction assays. Our theoretical studies indicate that a segment expanding between residues 19 and 27 of gp51 probably adopts an amphipathic beta-strand structure. We hypothesize that the amphipathic 19-27 structure of gp51 plays an important role in the process of membrane fusion by interacting with the fusion peptide or with another region of gp30. Mutational analysis disrupting the amphipathy of the 19-27 region strongly altered the fusogenic capacity of the gp51-gp30 complex. [less ▲]

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See detailImmunomodulatory properties of cyclic hexapeptide oxytocin antagonists
Geenen, Vincent ULg; Martens, Henri ULg; Robert, Françoise et al

in Thymus (1992), 20

A pharmacological manipulation of cryptocrine cell-to-cell signaling was tested by the investigation of the immunomodulatory properties of novel cyclic hexapeptide oxytocin (OT) antagonists (MSD Research ... [more ▼]

A pharmacological manipulation of cryptocrine cell-to-cell signaling was tested by the investigation of the immunomodulatory properties of novel cyclic hexapeptide oxytocin (OT) antagonists (MSD Research Laboratories). The compounds were found to significantly inhibit the productions of IL-1ß and IL-6 elicited by anti-CD3 treatment oh human whole blood cells cultures (WBC). Cytokine productions were more significantly reduced by OT antagonists in WBC derived from female volunteers than in those obtained from male donors, suggesting an influence of sex steroids on the expression of NHP receptors by immune cells. These observations support the concept of novel immunomodulating approaches through immune-specific neuropeptide antagonists, as well as the pharmacological value of such strategies in selective immunotherapy. [less ▲]

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See detailApplication de la théorie des systèmes à la thermique des bâtiments. Problèmes de modélisation, d'identification et de contrôle
Andre, Philippe ULg; Nicolas, Jacques ULg

in Revue générale de thermique (1992), 31(371), 600-615

La théorie est utilisée pour développer des modèles simplifiés, pour estimer, par des méthodes d'identification de systèmes, les variables d'état et les paramètres de ces modèles et enfin pour élaborer ... [more ▼]

La théorie est utilisée pour développer des modèles simplifiés, pour estimer, par des méthodes d'identification de systèmes, les variables d'état et les paramètres de ces modèles et enfin pour élaborer des stratégies de commande optimale pour le chauffage d'un bâtiment. L'ensemble de ces techniques est appliqué à un bâtiment solaire passif situé en Belgique. [less ▲]

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See detailMemory Efficient Algorithms for the Verification of Temporal Properties
Courcoubetis, Constantin; Vardi, Moshe Y; Wolper, Pierre ULg et al

in Formal Methods in System Design (1992), 1

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See detailColour rendering of supplementary artificial lighting
Embrechts, Jean-Jacques ULg

in Color Research and Application (1992), 17(3)

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See detailQUENCHING OF A ROOM-TEMPERATURE FLUORESCENCE BAND AT 693-NM DURING PHOTOACTIVATION OF THE WATER-SPLITTING SYSTEM OF PHOTOSYSTEM-II IN FLASHED BARLEY LEAVES
Franck, Fabrice ULg; Dujardin, E.

in Photosynthesis Research (1992), 31(1), 41-47

The modifications of the room temperature fluorescence spectrum during the photoactivation of the water-splitting system by continuous illumination were investigated in flashed barley leaves. A blue shift ... [more ▼]

The modifications of the room temperature fluorescence spectrum during the photoactivation of the water-splitting system by continuous illumination were investigated in flashed barley leaves. A blue shift of the chlorophyll fluorescence band was detected during the first 2 min of illumination. During this shift, a decrease of the fluorescence intensity around 693 nm could be demonstrated in difference spectra and in second derivative spectra. This decrease is interpreted as a quenching of PS II fluorescence during the photoactivation. A relative fluorescence increase around 672 nm also occurred during the same period and is thought to reflect rapid light-induced chlorophyll formation. The flashed leaves contained small amounts of photoactive photochlorophyllide which could be removed by a short flash of intense white light given before continuous illumination. The fact that such flash had only weak effect on the 693 nm fluorescence decrease, whereas it strongly reduced the amplitude of the 672 nm fluorescence increase, favours the above interpretations. [less ▲]

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See detail"Arterialization", "revascularization" , "rearterialization" - what's in a name?
D'Silva, Milbhor; Pirenne, Jacques; Bonnet, Pierre ULg et al

in Transplant International (1992), (5), 121-122

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See detailDéveloppement d'un Gestionnaire Automatisé de Bibliographies selon les normes de l'American Psychological Association (GABI APA Style)
Thirion, Paul ULg

in Revue. Informatique et Statistique dans les Sciences Humaines (1992), XXVIII(1-4), 251-284

Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This ... [more ▼]

Nowadays, there are plenty of complete and user-friendly database management systems. However, most of them only produce poorly organized raw data, generally lacking of internal consistency. This situation remains awkward, especially for scientists who have regularly to report references in an extremely ruled international format. GABI APA Style was built in titis context. GABl APA Style is a reference manager software using the presentation rules of the American Psychological Association (A.P.A.) It was written in Clipper language conforming to the relational database principle. The initial aim was to elaborate a software to centralize references, filling in the intellectual background of the Department od Psychology and Educational Sciences of Liège University. Special attention was paid to the ergonomic and easy-to-use aspects of the software, just as the possibilities of transfers with other applications. [less ▲]

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See detailAltered Capillary Filtration Coefficient in Parathion- and Paraoxon-Induced Edema in Isolated and Perfused Rabbit Lungs
Delaunois, Annie; Gustin, Pascal ULg; Ansay, Michel

in Toxicology and Applied Pharmacology (1992), 116(2), 161-169

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs ... [more ▼]

Changes in pulmonary endothelium permeability and in microvascular hemodynamics induced by parathion (Pth) and paraoxon (Pox), its active metabolite, were investigated in isolated, perfused rabbit lungs. Blood-free perfusate was recirculated through isolated and ventilated lungs in an isogravimetric state and in zone III conditions. The arterial/venous/double occlusion technique was used to divide the total vascular resistance (Rt) into four components: arterial, precapillary, postcapillary, and venous. The capillary filtration coefficient (Kfc) was evaluated by measuring the amount of fluid filtering through the endothelium when the arterial and venous pressures were suddenly increased. Pth and Pox induced pulmonary edema by increasing endothelium permeability without changing the hemodynamic parameters at any level of the vascular bed. The Kfc value increased progressively, reaching a maximum (Emax) 60 min after administration of organophosphate (558 ± 65% (n = 5) and 707 ± 109% (n = 5) of baseline values, for Pth and Pox, respectively). During the next 60 min, it decreased. The time course of Pox-induced changes in Kfc was similar to that obtained with Pth. The concentration-response curve (Emax) expressed as a percentage of the baseline value versus the logarithm of the malor Pth concentration, ranging from 2 × 10−5 to 4 × 10−4 image) was linear (y = 1661.1 + 327.3x, R = 0.89, p < 0.001, N = 14). Piperonyl butoxide (4 × 10−4 image), an inhibitor of cytochrome P450, had a strong protective effect against Pth (4 × 10−4 image)-induced alterations of endothelium permeability (n = 5, p < 0.001). The effects of Pox (4 × 10−4 image) on Kfc were completely abolished by pretreatment with 10−5 image atropine, as shown by the significantly lower Emax value recorded in atropine-pretreated lungs (129 ± 33%, n = 4) than in Pox-treated lungs (707 ± 109%, n = 5, p < 0.001). The effects of Pth, on the other hand, were only partially inhibited, since the Emax value recorded in atropine-pretreated lungs (196 ± 20%, n = 4) remained significantly higher than that recorded for control lungs (129 ± 15%; n = 5; p < 0.05). These results show that isolated and perfused rabbit lungs constitute and appropriate model for studying the direct pulmonary effects of organophosphates. The edema-inducing action of Pth depends on its activation by conversion to Pox in the lung tissue. It can be explained by an increase in endothelium permeability. This effect is mediated principally by muscarinic receptors [less ▲]

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See detailCaractérisation du sol vis-à-vis de l'assainissement.
Debbaut, Vincent ULg

in Tribune de l'Eau (La) (1992), 45(560), 57-66

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See detailThe 19-27 Amino-Acid Segment Of Gp51 Adopts An Amphiphilic Structure And Plays A Key Role In The Fusion Events Induced By Bovine Leukemia-Virus
Voneche, V.; Callebaut, I.; Kettmann, Richard ULg et al

in Journal of Biological Chemistry (1992), 267(21),

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S ... [more ▼]

Previous results indicate that the external glycoprotein gp51 of bovine leukemia virus plays an important role in the process of cell fusion induced by bovine leukemia virus (Bruck, C., Mathot, S., Portetelle, D., Berte, C., Franssen, J. D., Herion, P., and Burny, A. (1982) Virology 122, 342-352; Voneche, V., Portetelle., D., Kettmann, R., Willems, L., Limbach, K., Paoletti, E., Ruysschaert, J. M., Burny, A., and Brasseur, R. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3810-3814) and suggest that a region encompassing residues 23 and 25 of gp51 is involved in this process (Portetelle, D., Couez, D., Bruck, C., Kettmann, R., Mammerickx, M., Van der Maaten, M., Brasseur, R., and Burny, A. (1989) Virology 169, 27-33; Mamoun, R., Morisson, M., Rebeyrotte, N., Busetta, B., Couez, D., Kettmann, R., Hospital, M., and Guillemain, B. (1990) J. Virol. 64, 4180-4188). X-ray diffraction studies performed on envelope glycoproteins of influenza virus indicate that the NH2-terminal part of the external glycoprotein lies very close to the fusion peptide. The same overall structure seems to exist in human immunodeficiency virus as suggested by site-directed mutagenesis followed by syncytia induction assays. Our theoretical studies indicate that a segment expanding between residues 19 and 27 of gp51 probably adopts an amphipathic beta-strand structure. We hypothesize that the amphipathic 19-27 structure of gp51 plays an important role in the process of membrane fusion by interacting with the fusion peptide or with another region of gp30. Mutational analysis disrupting the amphipathy of the 19-27 region strongly altered the fusogenic capacity of the gp51-gp30 complex. [less ▲]

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See detailLa régulation de l'expression des gènes du virus de la varicelle et du zona
Piette, Jacques ULg; Defechereux, Patricia; Baudoux, Laurence et al

in Annales de Médecine Vétérinaire (1992), 136(8), 627-635

Varicella-zoster virus (VZV) belongs to the alphaherpesvirus family and shares many important structural and functional similarities with other members of the family such as herpes simplex virus type 1 ... [more ▼]

Varicella-zoster virus (VZV) belongs to the alphaherpesvirus family and shares many important structural and functional similarities with other members of the family such as herpes simplex virus type 1 (HSV-1). VZV is responsible for two different clinical syndromes, varicella which is the result of the primary infection and zoster which is due to virus reactivation remaining latent in the peripheral nervous system. VZV DNA is 124,884 base pair long and encodes four regulatory proteins (IE4, IE61, IE62 and IE63). Using transient expression systems, we have shown that IE4, IE62 and IE63 can regulate the expression of an indicator gene driven by various VZV promoter regions, demonstrating that these proteins play important roles in the infectious cycle. [less ▲]

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See detailTransition Rates in the 3d2 Configuration of the Calcium Isoelectronic Sequence
Biémont, Emile ULg; Hansen, J. E.; Quinet, Pascal ULg et al

in Journal of Physics : B Atomic Molecular & Optical Physics (1992), 25

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See detailLe Szondi des "primitifs"
Stassart, Martine ULg

in Szondiana (1992), 12(1), 64-70

The authors have tested with help of Szonditest 68 male Tarahumaras from 5 to 80 years old. It appears that there is no difference between all these subjects. Also it seems that there is only one pattern ... [more ▼]

The authors have tested with help of Szonditest 68 male Tarahumaras from 5 to 80 years old. It appears that there is no difference between all these subjects. Also it seems that there is only one pattern of personnality by them. They have no individual but a collective ego and the drives are oriented in the same direction. That is probably true for the other socalled primitive people. [less ▲]

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See detailThe formation and enzymatic repair of DNA modifications caused by haloethylnitrosoureas and related compounds
Ludlum, D.; Habraken, Yvette ULg; Carter, C. et al

in Nucleic Acids Symposium Series (1992), 105

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See detailQuelle répression pour le blanchiment des bénéfices tirés des fraudes. Aspects de droit international et comparé
Flore, Daniel ULg; Van den Wyngaert, Ch.; Tulkens, F. et al

in La protection juridique des intérêts financiers des Communautés européennes (1992)

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See detailAdhésines connues et inconnues chez les Escherichia coli isolées de cas de diarrhée du veau
Pohl, P.; Van Muylem, K.; Lintermans, P. et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailHistory and Dispossession in John Glenday's Poetry
Pagnoulle, Christine ULg

in Ecosse : Littérature et Civilisation (1992), 12

This short essay discusses Glenday's poetic exploration of history, especially the tragedy of dispossession during the enclosure movement.

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See detailModalités d'utilisation d'un abri par des taurillons au pâturage
Vandenheede, Marc ULg; Nicks, Baudouin ULg; Canart, Bernard et al

in Annales de Médecine Vétérinaire (1992), 136

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See detailDynamique du carbone inorganique dans l'estuaire de l'Escaut. Premiers résultats
Frankignoulle, Michel; Bourge, Isabelle; Canon, Christine et al

in Bulletin de la Société Royale des Sciences de Liège (1992), 61

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See detailFusogenic Segments Of Bovine Leukemia-Virus And Simian Immunodeficiency Virus Are Interchangeable And Mediate Fusion By Means Of Oblique Insertion In The Lipid Bilayer Of Their Target-Cells
Voneche, V.; Portetelle, Daniel ULg; Kettmann, Richard ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (1992), 89(9),

Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis indicates ... [more ▼]

Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis indicates that (i) both BLV envelope glycoproteins gp51 and gp30 are necessary for cell fusion; (ii) insertion of the N-terminal segment of gp30 (fusion peptide) into the lipid bilayer in an oblique orientation, as predicted by computer conformational analysis, results in fusogenic capacities higher than insertion in a perpendicular or parallel orientation; and (iii) replacement of the BLV fusion peptide with its simian immunodeficiency virus counterpart does not modify the fusogenic capacity of the BLV glycoprotein. [less ▲]

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See detailProdelphinidins from Ribes nigrum
Tits, Monique ULg; Angenot, Luc ULg; Poukens, P. et al

in Phytochemistry (1992), 31(3), 971-973

Ribes nigrum leaves yielded three anti-inflammatory prodelphinidins. these compounds were identified and characterized; two known prodelphinidin dimers gallocatechin-(4-8)-epigallocatechin and ... [more ▼]

Ribes nigrum leaves yielded three anti-inflammatory prodelphinidins. these compounds were identified and characterized; two known prodelphinidin dimers gallocatechin-(4-8)-epigallocatechin and gallocatechin-(4-8)-gallocatechin found together for the first time and a new prodelphinidin trimer galocatechin-(4-8)-gallocatechin-(4-8)-gallocatechin. [less ▲]

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