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See detailActivity and functional interaction of alternative oxidase and uncoupling protein in mitochondria from tomato fruit.
Sluse, Francis ULg; Jarmuszkiewicz, W.

in Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Medicas e Biologicas (2000), 33

Cyanide-resistant alternative oxidase (AOX) is not limited to plant mitochondria and is widespread among several types of protists. The uncoupling protein (UCP) is much more widespread than previously ... [more ▼]

Cyanide-resistant alternative oxidase (AOX) is not limited to plant mitochondria and is widespread among several types of protists. The uncoupling protein (UCP) is much more widespread than previously believed, not only in tissues of higher animals but also in plants and in an amoeboid protozoan. The redox energy-dissipating pathway (AOX) and the proton electrochemical gradient energy-dissipating pathway (UCP) lead to the same final effect, i.e., a decrease in ATP synthesis and an increase in heat production. Studies with green tomato fruit mitochondria show that both proteins are present simultaneously in the membrane. This raises the question of a specific physiological role for each energy-dissipating system and of a possible functional connection between them (shared regulation). Linoleic acid, an abundant free fatty acid in plants which activates UCP, strongly inhibits cyanide-resistant respiration mediated by AOX. Moreover, studies of the evolution of AOX and UCP protein expression and of their activities during post-harvest ripening of tomato fruit show that AOX and plant UCP work sequentially: AOX activity decreases in early post-growing stages and UCP activity is decreased in late ripening stages. Electron partitioning between the alternative oxidase and the cytochrome pathway as well as H+ gradient partitioning between ATP synthase and UCP can be evaluated by the ADP/O method. This method facilitates description of the kinetics of energy-dissipating pathways and of ATP synthase when state 3 respiration is decreased by limitation of oxidizable substrate. [less ▲]

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See detailDynamics and three-dimensional localization of ribosomal RNA within the nucleolus.
Thiry, Marc ULg; Cheutin, T.; O'Donohue, M. F. et al

in RNA (New York, N.Y.) (2000), 6(12), 1750-61

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely ... [more ▼]

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely unexplored. Here, we employed a nondestructive method for the incorporation of BrUTP into the RNA of living cells. By using pulse-chase experiments, three-dimensional image reconstructions of confocal optical sections, and electron microscopy analysis of ultrathin sections, we were able to describe topological and spatial dynamics of rRNAs within the nucleolus. We identified the precise location and the volumic organization of four typical subdomains, in which rRNAs are successively moving towards the nucleolar periphery during their synthesis and processing steps. The incorporation of BrUTP takes place simultaneously within several tiny spheres, centered on the fibrillar centers. Then, the structures containing the newly synthesized RNAs enlarge and appear as compact ringlets disposed around the fibrillar centers. Later, they form hollow spheres surrounding the latter components and begin to fuse together. Finally, these structures widen and form large rings reaching the limits of the nucleoli. These results clearly show that the transport of pre-rRNAs within the nucleolus does not occur randomly, but appears as a radial flow starting from the fibrillar centers that form concentric rings, which finally fuse together as they progress toward the nucleolar periphery. [less ▲]

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See detailThymic neuroendocrine self-antigens. Role in T-cell development and central T-cell self-tolerance
Geenen, Vincent ULg; Martens, Henri ULg; Brilot, Fabienne et al

in Annals of the New York Academy of Sciences (2000), 917

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See detailLa station de l'Hermitage à Huccorgne: un habitat gravettien de plein-air en Belgique
Straus, Lawrence; Otte, Marcel ULg; Noiret, Pierre ULg et al

in Notae Praehistoricae (2000), 20

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See detailRestoration of thalamocortical connectivity after recovery from persistent vegetative state
Laureys, Steven ULg; Faymonville, Marie-Elisabeth ULg; Luxen, André ULg et al

in Lancet (2000), 355(9217), 1790-1791

Moreover, the performance on these factors is correlated to different anterior and posterior

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See detailProgress in Arabidopsis genome sequencing and functionnal genomics.
Wambutt, R.; Portetelle, Daniel ULg; Vandenbol, Micheline ULg et al

in Journal of Biotechnology (2000), 78

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See detailLa place quantitative et qualitative de la viande dans notre alimentation.
Mary, Arnaud; Sindic, Marianne ULg

in Dieta (2000), (22), 6-11

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See detailGuerres au Congo (1996-1999), acteurs et scénarios
Kabamba, Bob ULg

in cahiers du CEDAF (2000)

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See detailEffect Of Barley Fibres And Barley Intake On The Ileal Endogenous Nitrogen Losses In Piglets
Leterme, Pascal; Souffrant, Wb.; Thewis, André ULg

in Journal of Cereal Science (2000), 31(3), 229-239

Ileal endogenous N losses (ENL) were measured, using the 15N isotope dilution technique, in piglets (17 kg) fed different barley genotypes (naked, spring, winter with low/high beta-glucan content) or ... [more ▼]

Ileal endogenous N losses (ENL) were measured, using the 15N isotope dilution technique, in piglets (17 kg) fed different barley genotypes (naked, spring, winter with low/high beta-glucan content) or diets containing 330, 530, 730 or 930 g of a blend of barleys/kg diet. The apparent protein and amino acid digestibilities of the naked variety and the winter variety with a high beta-glucan content were, on average, significantly higher than those for the other two varieties. The ENL were inversely correlated (p<0·01) with the apparent digestibilities but the difference between each of them was not significant (p>0·05). The ENL increased linearly with the inclusion level of barley in a N-free basal diet (2 mg endogenous N/g barley). Isolated hulls added to a N-free diet at the rate of 100 or 200 g/ kg diet exerted no significant effect on the ENL (1·80 g endogenous N/kg diet in both cases vs. 1·76 g for the basal level). On the contrary, the effect of isolated bran, measured under similar conditions, was significantly higher and dependent on fibre intake (2·59 and 3·31 g N/kg diet, respectively). It is concluded that the ENL are affected by the insoluble bran fibre but not by the hulls, nor by the level of beta-glucan. [less ▲]

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See detailRéhabilitation du pont barrage de Montignie-Saint-Christophe
Lejeune, André ULg; Pirotton, Michel ULg

in Cahiers de l'Urbanisme (Les) (2000)

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See detailLes arcanes de la prescription de l'action publique
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2000)

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See detailSignificance of random illite-vermiculite mixed layers in Pleistocene sediments of the northwestern Atlantic Ocean
Vanderaveroet, P.; Bout-Roumazeilles, V.; Fagel, Nathalie ULg et al

in Clay Minerals (2000), 35(4), 679-691

The clay mineralogy of Pleistocene sediments of eleven sediment cores at three ODP sites from 30 degrees N to 60 degrees N northwestern Atlantic Ocean has been investigated. The sediments are ... [more ▼]

The clay mineralogy of Pleistocene sediments of eleven sediment cores at three ODP sites from 30 degrees N to 60 degrees N northwestern Atlantic Ocean has been investigated. The sediments are characterized by the presence of random illite-vermiculite mixed layers (I-V) (up to 32% of the clay mineral assemblage). The I-V clays are much more abundant during interglacial periods than during glacial ones. They are attributed to detrital supply through erosion of high-latitude continental areas from which they are derived mainly from chemical weathering of micaceous phyllosilicates. Their spatial distribution and the specific conditions for their formation through weathering suggest that I-V mixed layers are mainly derived from the Canadian Shield. They were transported From their source to marine deposition areas by rivers, deep water masses or nepheloid layers. Due to the specific conditions required For the Formation of I-V, its occurrence and abundance are used as a palaeoclimate and palaeocirculation proxy for northwestern Atlantic Pleistocene sediment. [less ▲]

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See detailEvidence for expression of some Microtubule-associated Protein 1B in neurons as a plasma membrane glycoprotein.
Franzen, Rachelle ULg; Tanner, Sandy; Jaffe, Howard et al

in Journal of Neurochemistry (2000), 75

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See detailGeometric quantities associated to differential operators
Mathonet, Pierre ULg

in Communications in Algebra (2000), 28(2), 699-718

Denote by F_lambda the space of fields of tensor densities of weight -lambda over a manifold M. The space D^p_{lambda,mu} of differential operators of order at most p that map F_lambda onto F_mu are ... [more ▼]

Denote by F_lambda the space of fields of tensor densities of weight -lambda over a manifold M. The space D^p_{lambda,mu} of differential operators of order at most p that map F_lambda onto F_mu are modules over the Lie algebra of vector fields Vect(M). We compute all the Vect(M)-invariant mappings from D^p_{lambda,mu} onto F_nu. [less ▲]

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See detailGeneralization of automatic sequences for numeration systems on a regular language
Rigo, Michel ULg

in Theoretical Computer Science (2000), 244

Let L be an infinite regular language on a totally ordered alphabet (Σ,<). Feeding a finite deterministic automaton (with output) with the words of L, enumerated lexicographically with respect to <, leads ... [more ▼]

Let L be an infinite regular language on a totally ordered alphabet (Σ,<). Feeding a finite deterministic automaton (with output) with the words of L, enumerated lexicographically with respect to <, leads to an infinite sequence over the output alphabet of the automaton. This process generalizes the concept of k-automatic sequence for abstract numeration systems on a regular language (instead of systems in base k). Here, we study the first properties of these sequences and their relations with numeration systems. [less ▲]

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See detailLa trisomie 21 : étude d’une stratégie de mémorisation
Frenkel, Stéphanie ULg

in Le Journal des Psychologues (2000), 182

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See detailEffects Of Multinutrient Blocks And Polyethylene Glycol 4000 Supplies On Intake And Digestion By Sheep Fed Acacia Cyanophylla Lindl. Foliage-Based Diets
Moujahed, Nizar; Kayouli, Chedly; Thewis, André ULg et al

in Animal Feed Science & Technology (2000), 88(3-4), 219-238

The effect of multinutrient block supply and polyethylene glycol 4000 (PEG) on intake, digestion and rumen fermentation was studied in sheep fed with air-dried Acacia cyanophylla foliage (acacia)-based ... [more ▼]

The effect of multinutrient block supply and polyethylene glycol 4000 (PEG) on intake, digestion and rumen fermentation was studied in sheep fed with air-dried Acacia cyanophylla foliage (acacia)-based diet. In Experiment I, six Noire de Thibar breed sheep (BW 46 kg) were used in double 3 3 Latin square design. All diets included about 360 g of dry matter (DM) of oat±vetch hay and acacia ad libitum. Diet D0 was without a block supplement. Diet D1 included a urea± molasses±mineral block (B1). While D2 included another type of block (B2) that differed from B1 essentially by adding polyethylene glycol 4000. Each experimental period lasted 33 days (21 days for adaptation and two periods of 5 days for measurement separated by 2 days for rest). Feed intake, apparent digestibility of organic matter (OM), crude protein (CP) and crude ®bre (CF) and retained nitrogen (Nr) were measured by total faecal collection. In Experiment II, four Noire de Thibar sheep (BW 53 kg) ®tted with rumen cannulae were fed sequentially D0, D1 and D2, respectively, to 90% of intake levels as measured in Experiment I on metabolic weight (MW) base. Fermentation parameters in rumen liquid (pH, NH3-N, volatile fatty acid (VFA)) were measured at 0, 2, 5, 8, 10, 13, 16 and 21 h after the morning meal. Protozoal number and composition in rumen ¯uid were determined at 2 h sampling time. Solid digesta kinetics through the rumen was measured using chromium (Cr) mordanced acacia. The DM and CP degradation of acacia was determined using the nylon bag technique. Acacia had a relatively high content of condensed tannins (41 g kgÿ1 of DM) and acid detergent lignin (176 g kgÿ1 of DM). B1 and B2 were high in CP (381 and 369 g kgÿ1 of DM, respectively) compared to acacia (127 g kgÿ1 of DM, 20% bound to ®bre) and hay (75 g kgÿ1 of DM). The two kinds of blocks improved similarly (P < 0:001) acacia DM intake by 195 g. Block 1 increased (P < 0:001) only diet CP digestibility and Nr. Block 2 increased (P < 0:05) by a low extent DM and OM digestibility compared to D1, and remarkably (P < 0:001) CP digestibility and Nr compared to D0 and D1. Block supplies considerably increased water intake. Both B1 and B2 increased (P < 0:001) NH3-N and VFA concentrations in the rumen liquid with a positive speci®c effect of B2 (PEG). VFA molar proportion was signi®cantly modi®ed by B1 and B2. B1 and B2 decreased acetate proportion and increased propionate and butyrate proportions as compared to D0 (P < 0:001). Protozoal number in rumen ¯uid was increased signi®cantly by B1 and B2 (P < 0:001). PEG-containing block (B2) increased protozoal number as compared to B1. Both B1 and B2 increased (P < 0:001) solid out¯ow rate, with a speci®c increasing effect of B2 (D2) when compared to B1 (D1). Blocks supply did not modify in situ DM degradability of acacia, but B2 improved (P < 0:05) effective degradability of CP when compared to D0 and D1 which were similar. It is concluded that both B1 and B2 improved the nutritive value of acacia-based diet. A further positive effect was noted in D2 (PEG), especially for N metabolism. [less ▲]

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See detailIs the external beam PIXE method suitable for determining ancient silver artifact fineness?
Weber, Georges ULg; Guillaume, J.; Strivay, David ULg et al

in Nuclear Instruments & Methods in Physics Research Section B (2000), 161

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and ... [more ▼]

In archeometry, the non-destructive characteristic of an analytical method is always very attractive. For most of techniques, besides the need of sampling, difficulties can originate from the shape and the size of the silver artifacts to be analyzed. The external PIXE method should be an answer to this problem but several questions are arising from the implementation of the technique to such a material. The aim of this paper is to specify the experimental procedure as to take into account several parameters, which could induce dramatic errors. Among them it can be pointed out the superficial enrichment in silver, arising from the dissolution of copper and copper oxide, the surface roughness effects, the great importance of the stability of the geometric conditions. The accuracy and the precision of the method are considered within the scope of the results obtained in ancient times by the cupellation with ashbone cupels. In addition. the process involved to obtain silver alloys has been studied in order to define its influence on the real fineness of the objects. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailA comparison of respiratory pathways in fully habituated and normal non-organogenic sugarbeet callus
Bisbis, Badia; Wagner, Anneke; Kevers, Claire ULg et al

in Journal of Plant Physiology (2000), 156(3), 312-318

The respiration of cells and isolated mitochondria of a habituated non-organogenic (HNO) cell line (auxin- and cytokinin-independent) and of a normal (N) cell line (auxin- and cytokinin-requiring) from ... [more ▼]

The respiration of cells and isolated mitochondria of a habituated non-organogenic (HNO) cell line (auxin- and cytokinin-independent) and of a normal (N) cell line (auxin- and cytokinin-requiring) from sugarbeet (Beta vulgaris L.) was investigated. Oxygen uptake by both cells and mitochondria of the HNO fine was higher than that of the N line. Respiration in the presence of cyanide (i.e. capacity of the alternative pathway) was also higher in the HNO callus as compared with the N one. The measurements of O-2 uptake from isolated HNO and N mitochondria showed that addition of a mixture of substrates (NADH, succinate, malate and NAD) resulted in a higher respiration via the CN-resistant pathway in mitochondria From HNO cells. The activity of cytochrome c oxidase was twice as high as in the N cells as compared with the HNO cells. Immunoblots also showed that a higher alternative oxidase protein was present in HNO cells than in the N cells. A model showing the relationships between the different metabolic pathways previously studied in the HNO cells and the higher respiration via the CN-resistant pathway in the HNO cells is proposed. [less ▲]

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See detailImmunocytochemical localization of ionotropic glutamate receptors subunits in the adult quail forebrain
Cornil, Charlotte ULg; Foidart, Agnès ULg; Minet, Arlette ULg et al

in Journal of Comparative Neurology (The) (2000), 428

The excitatory amino acid glutamate is implicated in the central control of many neuroendocrine and behavioral processes. The ionotropic glutamate receptors are usually divided into the N-methyl-D ... [more ▼]

The excitatory amino acid glutamate is implicated in the central control of many neuroendocrine and behavioral processes. The ionotropic glutamate receptors are usually divided into the N-methyl-D-aspartate (NMDA) and non-NMDA (kainate and AMPA) subtypes. Subunits of these receptors have been cloned in a few mammalian species. Information available in birds is more limited. In quail, we recently demonstrated that glutamate agonists (kainate, AMPA, and NMDA) rapidly (within minutes) and reversibly decrease in vitro aromatase activity like several other manipulations affecting intracellular HCa21 pools. Aromatase catalyzes the conversion of androgens into estrogens which is a limiting step in the control by testosterone of many behavioral and physiologic processes. Therefore, glutamate could control estrogen production in the brain, but the anatomic substrate supporting this effect is poorly understood. In quail, aromatase is mainly localized in the preoptic-hypothalamic-limbic system. We visualized here the distribution of the major ionotropic glutamate receptors in quail by immunocytochemical methods by using commercial primary antibodies raised against rat glutamate receptor 1 and receptors 2-3 (GluR1, GluR2/3: AMPA subtype, Chemicon, CA), rat glutamate receptors 5-7 (GluR5-7: kainate subtype, Pharmingen, CA), and rat NMDA receptors (NMDAR1, Pharmingen, CA). Dense and specific signals were obtained with all antibodies. The four types of receptors are broadly distributed in the brain, and, in particular, immunoreactive cells are identified within the major aromatase cell groups located in the medial preoptic nucleus, ventromedial hypothalamus, nucleus striae terminalis, and nucleus taeniae. Dense specific populations of glutamate receptor immunoreactive cells are also present with a receptor subtype-specific distribution in broad areas of the telencephalon. The distribution of glutamate receptors, therefore, is consistent with the idea that these receptors could be located at the surface of aromatase-containing cells and mediate the rapid regulation of aromatase activity in a direct manner. [less ▲]

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See detailThe use of conducting polymers as cathodes for the electrochemical deposition of magnetic transition metal/rare alloys
Martinot, Lucien; Leroy, Delphine ULg; Zhan, H. et al

in Journal of Materials Chemistry (2000), 10(3), 729-735

We report the electrodeposition of Cu and Ni in aqueous solutions together with the deposition of lanthanides (Gd, Sm, Dy, Tb) and amorphous magnetic alloys of lanthanides with transition metals (Fe, Co ... [more ▼]

We report the electrodeposition of Cu and Ni in aqueous solutions together with the deposition of lanthanides (Gd, Sm, Dy, Tb) and amorphous magnetic alloys of lanthanides with transition metals (Fe, Co) onto various polymer cathodes in formamide solutions. We used conducting polymers (polypyrrole, PPy; polyethylenedioxythiophene, PEDOT) sprayed on different substrates and in addition composite materials based on carbon black (CB) mixed either with polyethylene (PE) or with polycarbonate (PC). In the latter case, the conducting material is easily shaped out in various forms. When deposited on some of these substrates, the alloys appear as an interesting material for magneto-optic recording. The electrochemical process was used for the preparation of Gd/Co and Dy/Fe alloys for which the measured coercitive fields ranged from 250–300 Oe (Dy/Fe) to about 350 Oe (Gd/Fe). We demonstrated also the feasibility of an additional electrografting of a transparent protective layer of polyacrylonitrile (PAN) in order to avoid the corrosion of the alloys by the atmosphere. [less ▲]

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See detailÀ la recherche de l'«art public» dans les villes de la Mésopotamie
Tunca, Önhan ULg

in Art&Fact (2000), 19

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See detailMethodological bias in home range and mobility estimates when locating radio-tagged trout, Salmo trutta, at different time intervals
Ovidio, Michaël ULg; Philippart, Jean-Claude ULg; Baras, Etienne

in Aquatic Living Resources (2000), 13(6), 449-454

Radio tracking has been extensively used to enhance our knowledge on the movement and home range of fish in general and salmonids in particular. However, the use of various temporal sampling protocols is ... [more ▼]

Radio tracking has been extensively used to enhance our knowledge on the movement and home range of fish in general and salmonids in particular. However, the use of various temporal sampling protocols is likely to overlook fish movements, and produce experimental artefacts, the amplitude of which is unknown and may compromise comparison of fish behaviours revealed by different protocols. Starting from a day-by-day tracking study of brown treat in Belgian waters (Aisne stream, nine fish, minimum 39 daily locations per fish), we re-examined their home range and mobility, through a subsampling process, as if the fish had been located at longer time intervals (2-14 days). The estimates from subsamples were compared to the original data set in order to quantify the corresponding reduction of accuracy from observed data, and how far this could be predicted on the basis of locating frequency. The results clearly indicate that all intervals longer than one day generally generate substantial biases (reduction of accuracy from 0 to 82% for home range and from 5 to 92% for mobility) but these can be partly corrected through the use of predictive models. This analysis demonstrates that any comparison between studies relying on different locating frequencies can generate some ambiguity when interpreting biological phenomena or geographical differences. (C) 2000 Ifremer/CNRS/INRA/IRD/Cemagref/Editions scientifrques et medicales Elsevier SAS. [less ▲]

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See detailUse of stable isotope to delineate amphipod trophic status in Antarctic food webs
Nyssen, Fabienne ULg

in Polish Archives of Hydrobiology (2000), 47

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See detailDeveloppement et utilisation d'un systeme de telemedecine pour le suivi medical des patients diabetiques.
Ordonez, A. J.; Rodriguez-Castro, C.; Zamora, J. et al

in Journées Annuelles de Diabetologie de l'Hôtel-Dieu (2000)

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See detailD'un procès à l'autre - pour une esthétique des médias
Servais, Christine ULg

in Recherches en Communication (2000), 13

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See detailPharma-clinics. Le medicament du mois. La moxonidine (Moxon).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(1), 61-3

Moxonidine (Moxon, Solvay Pharma) is the first member of a new class of centrally-acting antihypertensive agents. The selective activation of central I1 imidazoline receptors results in an inhibition of ... [more ▼]

Moxonidine (Moxon, Solvay Pharma) is the first member of a new class of centrally-acting antihypertensive agents. The selective activation of central I1 imidazoline receptors results in an inhibition of peripheral sympathetic activity and produces arterial vasodilatation. Moxonidine is indicated in the treatment of essential arterial hypertension, at a usual daily dose of 0.4 mg (initial dose of 0.2 mg/day), in one administration per day. Its tolerance profile is better than that of other centrally-acting antihypertensive agents which stimulate alpha-2 adrenergic receptors, and similar to that of medications of other classes. As monotherapy, the antihypertensive efficacy of moxonidine is similar to that of most other antihypertensive agents. In case of insufficient response, moxonidine may be associated with other antihypertensive compounds, which leads to a better efficacy with no deterioration of its good tolerance profile. [less ▲]

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See detailSystemic Induction Of Phytoalexins In Cucumber In Response To Treatments With Fluorescent Pseudomonads
Ongena, MARC ULg; Daayf, F.; Jacques, Philippe ULg et al

in Plant Pathology (2000), 49(4),

The Pseudomonas putida isolate BTP1 and its sid2 mutant M3 were recently reported to protect cucumber against Pythium aphanidermatum root rot. This protection was mainly associated with an accumulation of ... [more ▼]

The Pseudomonas putida isolate BTP1 and its sid2 mutant M3 were recently reported to protect cucumber against Pythium aphanidermatum root rot. This protection was mainly associated with an accumulation of antifungal phenolics in the treated roots. In this study, analyses of root extracts from split-root experiments showed that these phytoalexins were produced systemically. Indeed, several antifungal molecules accumulated similarly in both treated and nontreated root parts of plants protected against P. aphanidermatum with BTP1 or M3. In addition, analyses of leaf samples also revealed increased amounts of fungitoxic molecules in PGPR-treated plants, although the nature of these molecules appeared to be different from those detected in roots. The antifungal compounds isolated both from roots and leaves were mainly detected in acid-hydrolyzed extracts containing aglycones. These results suggest that PGPR can elicit phytoalexins systemically in cucumber and that the overall defence response is not based on a single phytoalexin but is chemically complex and organ-specific. [less ▲]

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See detailL'humanisme face au terrorisme
Seron, Vincent ULg

in Cahiers de défense sociale (2000)

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See detailEvaluation des concentrations plasmatiques en anti-oxydants, anticorps contre les LDL oxydees et homocysteine dans un echantillon de la population liegeoise
Pincemail, Joël ULg; Siquet, Jean ULg; Chapelle, Jean-Paul ULg et al

in Annales de Biologie Clinique (2000), 58(2, Mar-Apr), 177-85

A large number of epidemiological and clinical studies suggest that oxidative stress plays an important role in the development of cardiovascular diseases. In this way, following reference values in ... [more ▼]

A large number of epidemiological and clinical studies suggest that oxidative stress plays an important role in the development of cardiovascular diseases. In this way, following reference values in plasmatic antioxidants have been determined in a group of 123 blood donors (94 males, 29 females; age: 21-64 years) living in the surroundings of Liege, Belgium: vitamin A (1.5-3.62 mmol/l), vitamin C (3.68-75.21 mmol/l), vitamin E (16.98-46.46 mmol/l), ratio vitamin E/cholesterol (3.92-8.32 mmol/mmol), selenium (0.66-1.26 mmol/l), sulphydryl proteins (216-556 mmol/l), uric acid (174-477 mmol/l), superoxide dismutase (542-852 IU/g hemoglobine), glutathion peroxidase (39.55-91.83 IU/g hemoglobine). Only a few number of subjects were found with values corresponding to high risk of deficiency in antioxidants although low values in vitamin C (< 11.35 mmol/l) and in selenium (< 0.75 mmol/l) were respectively observed in 5.69 and 10.5% of our subjects. Autoantibodies against oxidized LDL, as marker of oxidative stress, and homocysteine, as a risk factor of atherosclerosis involved in the development of oxidative stress, have also been investigated. Approximatively 40% of the population presented values higher than the superior limit mean value (20.3% > 650 IU/l in autoantibodies and 19.5% > 15.2 mmol/l in homocysteine) that are, however, not correlated with age or low levels in antioxidants. The effect of smoking (25% of the population) contributed to significantly decrease vitamin C, selenium and glutathion peroxidase concentrations by 31.9 and 13% when compared to nonsmokers. Intake of 1 to 4 fruits per day resulted in a significant increase of 56.9% in vitamin C when compared to nonconsumers (26.8% of the population). In contrast, homocysteine concentrations were significantly decreased by 21.4% in fruits consumers. Thank to the development of methods allowing the routine dosage of all these parameters, general practitioners can now easily establish the oxidative stress status of their patients and, as fonction of getting patterns, detect populations at risk of developing cardiovascular diseases. [less ▲]

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See detailEffet de l’ammoniac sur la fibre C impliquée dans le réflexe de la toux chez le porc
Moreaux, B.; Nemmar, R.; Gustin, Pascal ULg

in Journées de la Recherche Porcine en France (2000), 32

The effect of ammonia on the C-fibre which is involved in the citric acid induced coughing reflex was assessed. The piglets were exposed during a period of 24 hours or 4 days to a concentration of 15 or ... [more ▼]

The effect of ammonia on the C-fibre which is involved in the citric acid induced coughing reflex was assessed. The piglets were exposed during a period of 24 hours or 4 days to a concentration of 15 or 30 ppm ammonia in an inhalation chamber . During this challenge, the animais underwent cough induction tests at two days intervals. Another group was exposed to ammonia (30 ppm) for 48 hours, after this period, substance P was assayed in liquids collected from broncho-alvealor and tracheal washings (BAL and TAL) and in tracheal and airway mucosa . Ammonia (30 ppm) induced an inhibition 0f the coughing reflex in pigs. The minimum period of exposure necessary to provoke this effect was 48 hours. The same ammonia concentration aiso induced o significant increase in substance P concentrations in BAL and TAL and a significant decrease in concentrations of the tracheal mucosa. We conclude that ammonia at o concentration of 30 ppm inhibits the citric acid induced coughing reflex. The effect was partly mediated by the release of substance P from the C-fibre. [less ▲]

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See detailLes non-recommandations dans le traitement de l'arthrose et de la polyarthrite rhumatoïde, ou pourquoi la médecine basée sur le niveau de preuve ne s'applique pas (encore) à la rhumatologie
Malaise, Michel ULg

in Revue Médicale de Liège (2000), 55(5), 466-475

The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can ... [more ▼]

The speed with which the phrase "Evidence-Based Medicine" has entered our language has been astonishing. Virtually all medical areas are concerned, but it probably applies best when clearcut diagnosis can be made or when mortality or well-defined morbidity are the outcomes, two conditions not really frequently encountered in rheumatology. We will discuss why rheumatology is probably not ready yet for the concept and will systematically review why "Evidence-Based Medicine" could in fact be "evidence-biased medicine". We will emphasize why evidence-based medicine can not replace the personal experience and knowledge of patients, two major corner-stones in the clinician's daily work, but should simply be an access to scientific data for the benefit of both patient and physician. [less ▲]

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See detailL'etude clinique du mois. Insulino-independance prolongee apres transplantation d'ilots de langerhans chez le patient diabetique de type 1: l'aboutissement d'un reve?
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(8), 803-5

A Canadian research team recently reported a series of 7 consecutive patients with type 1 brittle diabetes who could achieve sustained excellent metabolic control in the absence of insulin therapy after ... [more ▼]

A Canadian research team recently reported a series of 7 consecutive patients with type 1 brittle diabetes who could achieve sustained excellent metabolic control in the absence of insulin therapy after successful islet transplantation. This exceptional success, which contrasts with previous less favourable results, is probably due to the transplantation of a higher number of islets of good quality and to the use of a new glucocorticoid-free immunosuppressive regimen. These remarkable results which provide proof of the principle that islet transplantation can be reproducibly successful, at least for one year, may raise new hope in patients with type 1 diabetes. However, the problem of supply and demand of islets is huge and will require a careful, and probably difficult, selection of the best candidates to benefit from this new therapeutic approach. [less ▲]

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See detailEpidemiologische bewaking van boviene spongiforme encefalopathie in Belgïe: Jaaroverzicht voor 1998
Saegerman, Claude ULg; Dechamps, P.; Vanopdenbosch, E. et al

in Vlaams Diergeneeskundig Tijdschrift (2000), 69

In 1998 werden 6 runderen tussen de 54 en 71 maanden ouderdom, afkomstig van de provincies West-Vlaanderen (3 gevallen), Oost-Vlaanderen (2 gevallen) en Luik (1 geval), gediagnostiseerd als gevallen van ... [more ▼]

In 1998 werden 6 runderen tussen de 54 en 71 maanden ouderdom, afkomstig van de provincies West-Vlaanderen (3 gevallen), Oost-Vlaanderen (2 gevallen) en Luik (1 geval), gediagnostiseerd als gevallen van boviene spongiforme encephalopathie (BSE). De hypotheses betreffende de oorsprong van de infectie op zijn de volgende : het optreden van sporadische gevallen zonder duidelijk definieerbare oorzaak; de mogelijke kruiscontaminatie tussen voeder voor monogastrische dieren met daarin dierlijk meel en voeder voor herkauwers waarin geen dierlijk meel is verwerkt en dit tijdens het fabricatieproces, de stockage, het transport of de distributie; het gebruik van dierlijk beendermeel in het voeder voor runderen geproduceerd voor de ban (van kracht vanaf 27/7/1994). Algemeen kan men dus stellen dat in België de aanwezigheid van gecontamineerd diermeel als risicofactor voor BSE niet kan worden uitgesloten. De oorsprong van deze diermelen kon nog niet gedetermineerd worden. [less ▲]

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See detailTracabilite dans la filiere animale.
Portetelle, Daniel ULg; Haezebroeck, V.; Mortiaux, F. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(4),

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See detailSeasonal changes of pCO(2) over a subantarctic Macrocystis kelp bed
Delille, Bruno ULg; Delille, D.; Fiala, M. et al

in Polar Biology (2000), 23(10), 706-716

The partial pressure of carbon dioxide (pCO(2)), calculated from pH and total alkalinity measurements. was monitored together with chlorophyll a and bacterioplankton biomass in shallow coastal water ... [more ▼]

The partial pressure of carbon dioxide (pCO(2)), calculated from pH and total alkalinity measurements. was monitored together with chlorophyll a and bacterioplankton biomass in shallow coastal water located inside and outside a giant kelp bed (Macrocystis pyrifera) situated in the Kerguelen Archipelago, Southern Ocean. In spite of large changes over a short time-scale pCO(2) variations over the year are large and exhibit a seasonal pattern in which the different stages of the annual biological turnover are well marked. The overall pattern of pCO(2) variations is related to biological activity (development of both photosynthesis and respiration) during almost the whole year. However, physical and thermodynamical constraints exert a strong influence on pCO(2) at meso time-scale (10 days) and/or when biological activity is weak. Macrocystis acts to maintain pCO(2) below saturation almost the whole year and large undersaturations (pCO(2) as low as 20 mu atm) were observed within the kelp bed. Furthermore, primary production of Macrocystis covers a period of 8 similar to 9 months a year from winter to late summer and the kelp bed seems to favour the spring phytoplanktonic bloom. The buffer factor beta indicates that, outside the kelp bed, inorganic carbon dynamics are mainly influenced by air-sea exchange and photosynthesis without calcification. Inside the kelp bed. beta suggests calcification by the epiphytic community. [less ▲]

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See detailLe controle glycemique chez le patient diabetique. Recommandations apres les etudes DCCT et UKPDI.
Paquot, Nicolas ULg; Scheen, André ULg; Lefebvre, Pierre ULg

in Revue Médicale de Liège (2000), 55(5), 372-5

Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies ... [more ▼]

Diabetes mellitus is a chronic disorder characterized by microvascular and cardiovascular complications that substantially increase the morbidity and mortality associated with the disease. Several studies showed the association between the complications of diabetes and elevated blood glucose levels. Clinical trials have also demonstrated that treatment that lowers blood glucose reduces the risks of diabetic complications (mainly microvascular complications). The control of diabetes is assessed by frequent measurements of HbA1c. A reasonable goal in type 1 diabetes is a value of HbA1c < or = 7.2%. In type 2 diabetes, the optimal goal is a value of HbA1c < or = 6.5%, but a value < or = 8% seems to be an acceptable goal in these patients. [less ▲]

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See detailLa gestion integrée des déchets solides de Kigali (Rwanda)
Culot, Marc ULg; Nzeyimana, François

in Echos du COTA (2000), (87), 6-9

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See detailThermal unfolding of an intermediate is associated with non-arrhenius kinetics in the folding of hen lysozyme
Matagne, André ULg; Jamin, M.; Chung, E. W. et al

in Journal of Molecular Biology (2000), 297(1), 193-210

A variety of techniques, including quenched-flow hydrogen exchange labelling monitored by electrospray ionization mass spectrometry, and stopped-flow absorbance, fluorescence and circular dichroism ... [more ▼]

A variety of techniques, including quenched-flow hydrogen exchange labelling monitored by electrospray ionization mass spectrometry, and stopped-flow absorbance, fluorescence and circular dichroism spectroscopy, has been used to investigate the refolding kinetics of hen lysozyme over a temperature range from 2 degrees C to 50 degrees C. Simple Arrhenius behaviour is not observed, and although the overall rate of folding increases from 2 to 40 degrees C, it decreases above 40 degrees C. In addition, the transient intermediate on the major folding pathway at 20 degrees C, in which the alpha-domain is persistently structured in the absence of a stable beta-domain, is thermally unfolded in a sigmoidal transition (T-m approximate to 40 degrees C) indicative of a cooperatively folded state. At all temperatures, however, there is evidence for fast (similar to 25%) and slow (similar to 75%) populations of refolding molecules. By using transition state theory, the kinetic data from various experiments were jointly fitted to a sequential three-state model for the slow folding pathway. Together with previous findings, these results indicate that the alpha-domain intermediate is a productive species on the folding route between the denatured and native states, and which accumulates as a consequence of its intrinsic stability. Our analysis suggests that the temperature dependence of the rate constant for lysozyme folding depends on both the total change in the heat capacity between the ground and transition states (the dominant factor at low temperatures) and the heat-induced destabilization of the alpha-domain intermediate (the dominant factor at high temperatures). Destablization of such kinetically competent intermediate species is Likely to be a determining factor in the non-Arrhenius temperature dependence of the folding rate of those proteins for which one or more intermediates are populated. (C) 2000 Academic Press. [less ▲]

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See detailThe plasma environment of Mars : from the shocked solar wind down to the ionosphere
Trotignon, J.-G.; Parrot, M.; Cerisier, Jean-Claude et al

in Planetary and Space Science (2000), 48(12-14), 1181-1191

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See detailLes acteurs d'un système de justice pénale européen
Flore, Daniel ULg

in L’espace judiciaire pénal européen après Tampere (2000)

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See detailDescriptio Urbis Romae
Moreno, Paola ULg

in Revue Belge de Philologie et d'Histoire (2000)

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See detailThe relationship between airways inflammation and asthma severity.
Louis, Renaud ULg; Lau, L. C.; Bron, A. O. et al

in American Journal of Respiratory & Critical Care Medicine (2000), 161(1), 9-16

In order to investigate the relationship between airways inflammation and disease severity, and improve the understanding of persistent asthma, 74 asthmatics, with disease severity ranging from ... [more ▼]

In order to investigate the relationship between airways inflammation and disease severity, and improve the understanding of persistent asthma, 74 asthmatics, with disease severity ranging from intermittent, to mild to moderate and severe persistent (classified according to the Global Initiative for Asthma [GINA] guidelines), and 22 nonatopic control subjects were studied using the method of induced sputum. Sputum was analyzed for total and differential cell counts concentrations of albumin, and levels of eosinophil cationic protein (ECP), myeloperoxidase (MPO), and tryptase, inflammatory mediators reflecting eosinophil, neutrophil, and mast cell activation. Asthma severity (assessed by FEV(1), peak expiratory flow [PEF] variability, and daily symptom scores) and methacholine airways responsiveness were related to sputum eosinophilia and ECP. In addition, sputum neutrophilia and MPO levels correlated, albeit weakly, with PEF variability and symptom scores, respectively. Tryptase concentrations were raised in mild to moderate asthmatics. Albumin concentrations were significantly raised across the spectrum of asthma severity and correlated with those of tryptase and ECP. Despite treatment with either high doses of inhaled corticosteroids or oral corticosteroids, prominent eosinophilic inflammation with raised ECP was noted. This study points to persistent, disease severity-related airways inflammation in asthma, involving eosinophils, mast cells, and neutrophils, which is evident despite treatment with corticosteroids. [less ▲]

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See detailValidation and Prognostic Value of Plasma Lactate Measurement in Bovine Respiratory Disease
Coghe, Joost; Uystepruyst, Christophe; Bureau, Fabrice ULg et al

in Veterinary Journal (2000), 160(2), 139-146

The purpose of this study was to evaluate the accuracy of a portable blood lactate analyser for bovine blood and to study the relevance of plasma lactate concentration in the prognosis of bovine pulmonary ... [more ▼]

The purpose of this study was to evaluate the accuracy of a portable blood lactate analyser for bovine blood and to study the relevance of plasma lactate concentration in the prognosis of bovine pulmonary disorders.Measurements with the portable analyser were highly correlated (R = 0.94, P<0.0001) with the measurements of the reference method but significantly different (P<0.0001). The portable apparatus slightly overestimated plasma lactate concentration compared to the reference method (bias = + 0.412). Plasma lactate measurements on 109 calves suffering from acute bronchopneumonia showed increasing lactate concentrations with severity of the disease. A plasma lactate concentration higher than 3.6 mmol/L or 4 mmol/L, measured with the reference method and the portable analyser respectively, appeared to be a reliable prognostic indicator for mortality within 24 h. Consequently, this measurement could be very helpful to decrease economic losses in cases of bovine respiratory disease, by avoiding unnecessary treatment costs on cattle with poor prognosis. [less ▲]

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See detailBoundedness properties for time-varying nonlinear systems
Peuteman, Joan; Aeyels, Dirk; Sepulchre, Rodolphe ULg

in SIAM Journal on Control & Optimization (2000), 39(5), 1408-1422

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See detailDiagnostics of the jovian aurora deduced from ultraviolet spectroscopy: Model and HST/GHRS observations
Dols, V.; Gérard, Jean-Claude ULg; Clarke, J. T. et al

in Icarus: International Journal of Solar System Studies (2000), 147(1), 251-266

A model coupling an electron energy degradation code with a detailed synthetic spectrum of the H-2 Lyman and Werner band system is used to calculate the emerging auroral ultraviolet spectra from Jupiter's ... [more ▼]

A model coupling an electron energy degradation code with a detailed synthetic spectrum of the H-2 Lyman and Werner band system is used to calculate the emerging auroral ultraviolet spectra from Jupiter's atmosphere excited by electrons with different initial energy distributions. The atmospheric model is adapted from the vertical P-T profile measured by the Galileo probe and midlatitude model hydrocarbon photochemistry. Each altitude layer, with its own gas temperature, contributes to the emergent ultraviolet spectrum and the absorbers are vertically distributed within the source region of the auroral emissions. Examples of the calculated spectra are shown to validate the synthetic spectrum and to illustrate the importance of the electron energy distribution and the vertical structure. The model is then applied to the analysis of seven HST/GHRS spectra of the 1200-1700 Angstrom region obtained with 5-Angstrom resolution at various locations in the north and south Jovian aurora. These spectra have different color ratios which characterize the energy of the precipitated electrons, although they do not have a high enough spectral resolution to permit a determination of the H-2 temperature. We find that the characteristic energy of the assumed initial Maxwellian distribution ranges between 17 and 40 keV. A clear signature of acetylene absorption is observed near 1520, 1480, and 1440 Angstrom where the C2H2 cross section shows strong absorption peaks. The acetylene column abundance overlying the emission peak varies from 0.02 to 0.2 of the methane column. A better fit is obtained for some spectra when ethane absorption is added. The C2H6 column abundance varies from 0 to 0.5 of the methane column. These changes relative to methane are presumably the result of perturbations by heat released by the fast electron thermalization and/or perturbations to the hydrocarbon chemistry resulting from the production of H atoms by the aurora, A spectrum of the Io flux tube footprint and its trailing tail shows an ultraviolet color and hydrocarbon absorption quite similar to some of the main oval spectra, This observation suggests that the electrons of the Io flux tube are energized to a few tens of keV, similar to the electron precipitated in the main ovals and polar caps. Echelle spectra between 1216 and 1220 Angstrom at 0.07 Angstrom resolution are also compared with the model fitting best the mid-resolution spectra. It is found that the effective H-2 rovibrational temperature associated with the echelle spectra are significantly higher than predicted by the mid-latitude model. A large vertical temperature gradient just above the methane homopause due to large heating by auroral precipitation is a plausible explanation for this difference. (C) 2000 Academic Press. [less ▲]

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See detailLe droit d'apprendre à l'école, qui n'est pas un terrain de football
Beckers, Jacqueline ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), 3-4

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See detailEfficacy and tolerability of a monophasic oral contraceptive containing ethinylestradiol and drospirenone.
Huber, J.; Foidart, Jean-Michel ULg; Wuttke, W. et al

in European Journal of Contraception & Reproductive Health Care (2000), 5(1), 25-34

To assess the contraceptive reliability, cycle control and tolerability of a new monophasic oral contraceptive containing 30 g ethinylestradiol plus 3 mg drospirenone (Yasmin, Schering AG, Berlin, Germany ... [more ▼]

To assess the contraceptive reliability, cycle control and tolerability of a new monophasic oral contraceptive containing 30 g ethinylestradiol plus 3 mg drospirenone (Yasmin, Schering AG, Berlin, Germany), it was compared with an established oral contraceptive containing 30 g ethinylestradiol plus 150 g desogestrel (Marvelon, NV Organon, Oss, The Netherlands). METHODS: A randomized, open-label, 13-cycle study was performed at 80 European centers. Contraceptive reliability, cycle control, blood pressure, body weight, the incidence of adverse events and skin condition were assessed during 13 cycles of oral contraceptive use, and at follow-up. Subjects recorded body weight on three consecutive days pretreatment and weekly thereafter. RESULTS: Of 2069 women who started the study and received the trial preparations in a ratio of 4:1 (ethinylestradiol/drospirenone, n = 1657; ethinylestradiol/desogestrel, n = 412), 1615 completed the 13 cycles plus follow-up, providing data for over 23,000 evaluable cycles. Eleven pregnancies occurred during treatment, only one of which (in the ethinylestradiol/drospirenone group) could not be ascribed to user failure or interaction with other factors. Both preparations provided effective contraception and cycle control. Pre-existing acne and seborrhea were improved and blood pressure was essentially unchanged. The two treatments differed in their effect on body weight, the difference being statistically significant. In the ethinylestradiol/drospirenone group, there was a distinct decrease over the whole treatment phase, while a subtle and less distinct decrease was documented in the ethinylestradiol/desogestrel group. CONCLUSIONS: The combination of 30 g ethinylestradiol/3 mg drospirenone provides effective oral contraception, excellent cycle control, good tolerability and a level of weight loss that may have a significant beneficial effect on compliance in women with a tendency to weight gain due to water retention. [less ▲]

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See detailWhat do the needles, syringes, lancets and reagent strips of diabetic patients become in the absence of a common attitude? About 1070 questionnaires in diabetic clinics.
Bouhanick, B.; Hadjadj, S.; Weekers, Laurent ULg

in Diabètes & Métabolism (2000), 26(4), 288-93

The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable ... [more ▼]

The aim was to investigate the fate of injection and monitoring material after its use by diabetic patients in different countries (France, Belgium, Luxemburg, Switzeland and Tunisia). Some suitable containers are available for disposal but little is known about the attitudes of patients and physicians to them. 1 070 questionnaires were completed by patients (age: 50 +/- 18 years; diabetes duration: 15 +/- 11 years; 2.8 +/- 1.1 injections per day) visiting 109 doctors. Injections were done at home (72.6%), or both at home and at work (26.6%). At home: needles, syringes, lancets and reagent strips were thrown directly into the bin in 46.9%, 49.9%, 52.2% and 67.6% of cases, respectively; and in a closed plastic bottle in 29. 6%, 28.5%, 28.9% and 19.9% of cases, respectively. Specific containers were used in 8.6% and 6.3% of cases for needles and syringes, respectively. 62% of the bottles and containers were thrown directly into the bin, whereas 15.5% were returned to a pharmacy (4.5% taken to hospitals, 2.9% were burned). At work: 63% of the patients brought their needles and syringes home for disposal, 6.9% kept suitable containers at work and 30% threw their materials directly into local bins. We conclude that awareness should be increased and the organization of the collection of used material improved. [less ▲]

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See detailComposition chimique du nététu, condiment alimentaire produit par fermentation des graines du caroubier africain Parkia biglobosa (Jacq.) Benth.
Ndir, Babacar; Lognay, Georges ULg; Wathelet, Bernard ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(2), 101-105

The seed oils and cakes of netetu of different origins available on the Senegalian market have been studied to evaluate the nutritional potentialities of this important food condiment used in many African ... [more ▼]

The seed oils and cakes of netetu of different origins available on the Senegalian market have been studied to evaluate the nutritional potentialities of this important food condiment used in many African countries. The total oil content ranged from 141 to 349 g.kg-1. Careful gas chromatography and GC-MS (Gas Chromatography-Mass Spectrometry) investigations revealed seven major fatty acids among which linoleic (41.9–46.8% of the total fatty acids), oleic (12.6–14.6%), palmitic (10.2–11.3%), stearic (10.0–13.4%), and behenic (12.6–13.4%) predominate. Significant differences were observed between fermented and non-fermented seeds as well as between netetu of different origins. The tocopherol content was found very low (17.7 to 30.6 mg.100g-1 fat). The total amino acid patterns showed that beside high level of proteins (331 à 540 g.kg-1) and interesting levels of essential constituents, there is an important deficiency of tryptophane, cysteine, methionine and threonine. [less ▲]

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See detailPour concevoir et déployer des dispositifs d'accompagnement d'équipes éducatives dans l'élaboration de pratiques collectives
Mouvet, Bernadette ULg; Lenoir, Anne-Sophie; Massart, Valérie ULg et al

in Point sur la Recherche en Education (Le) (2000), 17

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See detailNutrient depletions in the Ross Sea and their relation with pigment stocks
Goeyens, Leo; Elskens, Marc; Catalano, Giulio et al

in Journal of Marine Systems (2000), 27

The present article depicts a first attempt to relate the governing nutrient uptake regime and phytopigment signature of the Ross Sea. Based on nutrient and phytopigment data obtained during two cruises ... [more ▼]

The present article depicts a first attempt to relate the governing nutrient uptake regime and phytopigment signature of the Ross Sea. Based on nutrient and phytopigment data obtained during two cruises in the Ross Sea, two distinct groups were recognised. The first one was characterised by moderate nutrient nitrate and silicic acid depletions in combination with relatively high diatom and Phaeocystis abundance. The second group showed very low nutrient depletions and very poor diatom abundance. Average depth specific nitrate depletions were 8.1 and 1.1 μM and average silicic acid depletions were 21.5 and 1.3 μM, respectively. The nutrient consumption patterns did not match the conditions of silicic acid excess (SEA) or nitrate excess areas (NEA), a clear trend being probably obscured by very poor seasonal maturity of several sampling stations. The contrast between both groups is largely explained by small differences in nitrogen uptake regime of the major phytoplankters. During early season, the diatoms meet the majority of their nitrogen requirements by nitrate uptake, with few exceptions where ammonium is the most important nitrogenous substrate. On average, their nitrate uptake capacity is lower than that of Phaeocystis (average specific nitrate uptake rates were 0.021 and 0.036 day y-1 for diatoms and Phaeocystis, respectively). The latter phytoplankton always shows predominance of nitrate uptake. Both groups are subject to inhibition of nitrate uptake when ammonium availability increases, and it is likely that the diatoms are more sensitive to the inhibitory effect of ammonium. [less ▲]

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See detailL'immigrazione italiana in Belgio
Martiniello, Marco ULg

in I Viaggi di Erodoto (2000), 40

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See detailLa prescription des pensions alimentaires allouées par décision de justice. Note sous Liège, 18 octobre 1999
Kohl, Benoît ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2000)

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See detailThe Efficacy of Two Vaccination Schemes against Experimental Infection with a Virulent Amyxomatous or a Virulent Nodular Myxoma Virus Strain
Marlier, Didier ULg; Mainil, Jacques ULg; Boucraut-Baralon, C. et al

in Journal of Comparative Pathology (2000), 122(2-3, Feb-Apr), 115-22

Two types of myxomatosis vaccine are available commercially, namely, vaccine prepared from the Shope fibroma virus (SFV) and that prepared from an attenuated myxoma virus (MV) strain, e.gSG33. An ... [more ▼]

Two types of myxomatosis vaccine are available commercially, namely, vaccine prepared from the Shope fibroma virus (SFV) and that prepared from an attenuated myxoma virus (MV) strain, e.gSG33. An experiment was designed to compare two vaccination schemes for their ability to protect rabbits against challenge with either a virulent amyxomatous MV strain or a virulent nodular MV strain. Apart from a difference in the cutaneous expression of the disease, the two challenge strains resembled each other in respect of mortality rate, naso-conjunctival shedding of virus, and tissue infection. Vaccination with SFV alone failed to prevent clinical signs, naso-conjunctival shedding or tissue infection. Vaccination with SFV followed by a booster inoculation with SG33 protected rabbits against the development of clinical signs and significantly reduced both viral shedding in naso-conjunctival exudates and viral infection of eyelids, lungs and testes; virus was, however, isolated from testes of some surviving animals. [less ▲]

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See detailEntre science et action, le concept de réseau écologique
Mougenot, Catherine ULg; Melin, Eric ULg

in Natures Sciences Sociétés (2000), 8(3), 20-30

Le concept de réseau écologique est une notion récente. Mais à peine découvert, ne va-t-il pas produire la même confusion de sens que l'on dénonce souvent à propos de la biodiversité? Pour éclairer cette ... [more ▼]

Le concept de réseau écologique est une notion récente. Mais à peine découvert, ne va-t-il pas produire la même confusion de sens que l'on dénonce souvent à propos de la biodiversité? Pour éclairer cette question, cet article repose sur l'hypothèse que trois conceptions différentes se dessinent dans le concept de réseau écologique : protéger les espèces et leurs réseaux d'habitats, restaurer le réseau écologique au sein du paysage et planifier le réseau écologique. Ces trois conceptions construisent leur propre chemin de la science à l'action, c'est-à-dire qu'elles privilégient chacune leurs questions scientifiques, leurs ressources juridiques, leurs modes de gestion et les acteurs Impliqués, Dans ce débat, les trois conceptions que nous avons dégagées apparaissent de façon complémentaire, elles s'imbriquent l'une dans l'autre, mais aucune d'elles ne peut évacuer les autres. On peut dire que ce sont là trois façons de promouvoir la biodiversité. [less ▲]

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See detailPharma-clinics. Le medicament du mois. La levofloxacine (Tavanic).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(11), 1015-7

Levofloxacin, the (-)-(S)-enantiomer isolated from the racemate ofloxacin, is launched by Aventis under the trade name of Tavanic. This new oral and parenteral antibiotic belongs to the fluoroquinolone ... [more ▼]

Levofloxacin, the (-)-(S)-enantiomer isolated from the racemate ofloxacin, is launched by Aventis under the trade name of Tavanic. This new oral and parenteral antibiotic belongs to the fluoroquinolone family and exerts a bactericidal activity upon a large spectrum of microorganisms, including Gram negative and Gram positive bacilli (among which Streptococcus pneunomiae), and atypical respiratory pathogens. It also has interesting pharmacokinetic properties. Besides the classical indications of other fluoroquinolones (especially complicated urinary tract infections, including pyelonephritis, and severe skin and soft tissue infections), levofloxacin is indicated for the treatment of acute sinusitis, acute exacerbations of chronic bronchitis and community-acquired pneumonia. [less ▲]

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See detailL'herpèsvirus bovin de type 4 : virus pathogène ou passager?
Thiry, Etienne ULg; Markine-Goriaynoff, Nicolas; Minner, Frédéric et al

in Point Vétérinaire (2000), 31

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental ... [more ▼]

Bovine herpesvirus type 4 (BHV-4) is a ubiquitous herpesvirus in cattle. It has been isolated from animals showing a wide variety of clinical signs but few of the isolates have proven experimental pathogenicity. Species that are susceptible to BHV-4 include animals other than ruminants, notably cats and, surprisingly, a primate the owl monkey (Aotus trivirgatus). BHV-4 exists as a latent infection in mononuclear cells. In cattle, BHV-4 has been isolated in animals exhibiting ocular and respiratory conditions and it has been found in females with genital tract conditions such as post-partum metritis and vulvovaginitis. There is some epidemiological and experimental evidence that BHV-4 may be a cause of bovine abortion. There is no vaccine available in Europe and prevention is exclusively by hygiene measures. [less ▲]

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See detailNon-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions.
Piette, Véronique; Fillet, Marianne ULg; Lindner, W. et al

in Journal of Chromatography. A (2000), 875(1-2), 353-60

A non-aqueous capillary electrophoretic method developed with quinine and tert.-butyl carbamoylated quinine as chiral selectors for the enantioseparation of N-protected amino acids was applied to the ... [more ▼]

A non-aqueous capillary electrophoretic method developed with quinine and tert.-butyl carbamoylated quinine as chiral selectors for the enantioseparation of N-protected amino acids was applied to the investigation of other quinine derivatives as chiral additives. The optimum composition of the background electrolyte was found to be 12.5 mM ammonia, 100 mM octanoic acid and 10 mM chiral selector in an ethanol-methanol (60:40, v/v) mixture. Under these conditions, a series of chiral acids, as various benzoyl, 3,5-dinitrobenzoyl and 3,5-dinitrobenzyloxycarbonyl amino acid derivatives were investigated with regards to selectand-selector relationships and enantioselectivity employing quinine, quinidine, cinchonine, cinchonidine, tert.-butyl carbamoylated quinine, tert.-butyl carbamoylated quinidine, dinitrophenyl carbamoylated quinine and cyclohexyl carbamoylated quinine as chiral selector. [less ▲]

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See detailFactors controlling the distribution of diatoms and Phaeocystis in the Ross Sea
Goffart, Anne ULg; Catalano, Guilio; Hecq, Jean-Henri ULg

in Journal of Marine Systems (2000), 27

The spatial and temporal distributions of phytoplankton pigments were investigated in the western and south central Ross Sea during austral spring 1994 and summer 1990. Large gradients in biomass and ... [more ▼]

The spatial and temporal distributions of phytoplankton pigments were investigated in the western and south central Ross Sea during austral spring 1994 and summer 1990. Large gradients in biomass and phytoplankton community composition were observed both in the east-west and south-north directions, in relation to differences in water column structure and stability, which themselves depend on the processes of ice retreat within the different areas. Important are melting in the western Ross Sea, which induces strong stratification, and ice breakup and wind stress in the south central Ross Sea, which result in deep mixing and weakly stratified waters. In the western Ross Sea, the highest chl a concentrations observed in this study (129 - 358 mg m-2 in the upper 100 m) were tightly coupled to the stratified region of meltwater influence and were dominated by diatoms, as indicated by elevated fucoxanthin concentrations (89 - 239 mg m-2 in the upper 100 m). In the diatom bloom area, high levels of phaeophorbides a (maximum value of 192 mg . m-2 in the upper 100 m) indicated that the dominant grazers, identified as Limacina helecina and copepods (Hecq et al., 1992), transferred a sustained part of the diatom production to the herbivore trophic level. Synthesis of our data with published information suggests that the diatom bloom we observed in the western Ross Sea was dominated by the species Fragilariopsis curta, and occurs annually off the coast of Victoria Land from 72°30'S to 77°S within 100 to 250 km from the coastal ice edge. It is assumed to persist on the order of 2.5 - 3 months during summer. In the south central Ross Sea, which was characterized by a poorly or unstratified water column, moderate chl a concentrations (55 - 186 mg m-2 in the upper 100 m) were found in the polynya and in the ice edge area in early spring. 19'-hexanoyloxyfucoxanthin, a biomarker for Phaeocystis, was the major contributor to the total carotenoid abundance (29 - 132 mg m-2 in the upper 100 m), corroborating the hypothesis that Phaeocystis are well adapted to develop in a relatively mixed water column. At the northern limit of the polynya, a quite narrow (c. a. 30 km) diatom bloom (31 - 67 mg fucoxanthin m-2 in the upper 100 m) overlapped with the Phaeocystis bloom in the slightly stratified marginal ice zone. This was an area of increased grazing pressure by various types of herbivorous zooplankton, among which very large amounts of krill were observed. [less ▲]

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See detailQuelles stratégies pour favoriser le retour au travail du patient lombalgique ? Enseignement des expériences étrangères
Mairiaux, Philippe ULg

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2000), 37(1), 5-12

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See detailA Topological Reconstruction Theorem for $D^{\infty}$-Modules
Prosmans, Fabienne ULg; Schneiders, Jean-Pierre ULg

in Duke Mathematical Journal (2000), 102(1), 39-86

We prove that any perfect complex of $D^{\infty}-modules may be reconstructed from its holomorphic solution complex provided that we keep track of the natural topology of this last complex. This is to be ... [more ▼]

We prove that any perfect complex of $D^{\infty}-modules may be reconstructed from its holomorphic solution complex provided that we keep track of the natural topology of this last complex. This is to be compared with the reconstruction theorem for regular holonomic D-modules which follows from the well-known Riemann-Hilbert correspondence. [less ▲]

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See detailTextural properties of low-density xerogels
Alié, Christelle ULg; Benhaddou, Arnaud; Pirard, René ULg et al

in Journal of Non-Crystalline Solids (2000), 270(1-3), 77-90

The extent of shrinkage during drying is controlled by the balance between the capillary pressure developed in the pore liquid and the modulus of the solid network. One first method to obtain low-density ... [more ▼]

The extent of shrinkage during drying is controlled by the balance between the capillary pressure developed in the pore liquid and the modulus of the solid network. One first method to obtain low-density xerogels consists in strengthening TEOS-based alcogels by providing new monomers to the alcogel after gelation. In the second method, low-density xerogels are produced by surface modification (silylation) of the wet gel with trimethylchlorosilane. The capillary pressure is reduced and the presence of non-reactive species on the surface makes the shrinkage reversible. A reduction of the capillary pressure can be achieved by introduction of a substituted alkoxide 3-(2-aminoethylamino)propyltrimethoxysilane (EDAS) to a TEOS-based alcogel, synthesised in a single base-catalysed step. This additive acts as a nucleation agent leading to big silica particles (similar to 20 nm) with a low EDAS/TEOS ratio (similar to 0.03). The pores between those particles are also large and the drying stress is reduced. The textural properties of those three materials are compared: bulk densities of the samples modelled on the first and third method are varying in the same range (0.25-0.35 g/cm(3)) while xerogels obtained by the surface modification process are less dense (0.1-0.15 g/cm(3)). The biggest pores are observed in the third method. (C) 2000 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailPharma-clinics. Le medicament du mois. Le rofecoxib (Vioxx).
Scheen, André ULg

in Revue Médicale de Liège (2000), 55(7), 751-3

Rofecoxib (Vioxx, Merck Sharp & Dohme) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as a nonsteroidal anti-inflammatory drug (NSAID). It is indicated in the ... [more ▼]

Rofecoxib (Vioxx, Merck Sharp & Dohme) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as a nonsteroidal anti-inflammatory drug (NSAID). It is indicated in the symptomatic relief of pain due to osteoarthritis. The initial oral dosage of rofecoxib is 12.5 mg once daily in adults, and this dose may be increased up to a maximal dosage of 25 mg once daily if necessary. Its clinical efficacy seems to be similar to that of other NSAIDs at maximal recommended dosages, but its safety profile, especially gastrointestinal tolerance, is much better because of the COX-2 selectivity. Ongoing clinical trials are performed in patients with rheumatoid arthritis. [less ▲]

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See detailFar upstream sequences regulate the human prolactin promoter transcription
Van de Weerdt, Cécile ULg; Peers, Bernard ULg; Belayew, A. et al

in Neuroendocrinology (2000), 71(2), 124-37

The human prolactin gene is mainly expressed in pituitary lactotrope cells, but transcription from an alternative, far upstream promoter was detected in lymphoid, placental and mammary cells. We describe ... [more ▼]

The human prolactin gene is mainly expressed in pituitary lactotrope cells, but transcription from an alternative, far upstream promoter was detected in lymphoid, placental and mammary cells. We describe the transcriptional activity in rat pituitary cells of the complete region separating the two promoters, using transient transfection experiments. A far upstream activating region was only functional in combination with the prolactin promoter. DNaseI protection experiments revealed, in addition to binding sites for the pituitary-specific factor Pit-1, sites (e.g. SD1) for several ubiquitous factors and one lymphoid-specific factor (SD4). A single copy of the ubiquitous site SD1 or the lymphoid-specific site SD4 was unable to activate transcription of a heterologous promoter in pituitary cells. However, SD1 activated transcription in nonpituitary cells and SD4 was functional specifically in lymphoid cells. Five copies of a distal site (D8) activated transcription in each cell type tested. Gel retardation experiments show that this site binds the specific factor C/EBP in liver and a distinct factor in other cell types. Our results suggest that different elements within this large region direct specific expression from each promoter via a complex interplay between cell-specific and ubiquitous transcription factors. [less ▲]

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See detailChronique semestrielle de droit communautaire
Partsch, Philippe-Emmanuel ULg

in Journal des Tribunaux (2000)

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See detailDispersed Pd-Ag alloys for selective production of olefins from chlorinated alkanes
Heinrichs, Benoît ULg; Schoebrechts, Jean-Paul; Pirard, Jean-Paul ULg

in Studies in Surface Science and Catalysis (2000), 130

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See detailEffect of water extract of Moringa oleifera seeds on the hydrolytic microbial species diversity of a UASB reactor treating domestic wastewater.
Kalogo, Y.; Rosillon, Françis ULg; Hammes, F. et al

in Letters in Applied Microbiology (2000), 31(3), 259-264

The effect of a continuous supply of a water extract of Moringa oleifera seeds (WEMOS) on the hydrolytic microbial population of biomass grown in mesophilic upflow anaerobic sludge blanket reactors ... [more ▼]

The effect of a continuous supply of a water extract of Moringa oleifera seeds (WEMOS) on the hydrolytic microbial population of biomass grown in mesophilic upflow anaerobic sludge blanket reactors treating domestic wastewater was investigated. The WEMOS-treated sludge had seemingly a wider diversity, with enterobacter and klebsiella as dominant hydrolytic bacteria, compared with the control sludge. Additional tests indicated that various hydrolytic bacteria could degrade WEMOS. It appeared that a continuous supply of WEMOS to an anaerobic digester, treating domestic wastewater, increased the diversity of hydrolytic bacteria and therefore enhanced the biological start-up of the reactor. [less ▲]

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See detailTreating families of individuals with traumatic brain injury : Presentation of clinical cases approached from a structural therapy perspective
Laroi, Frank ULg

in Journal of Family Psychotherapy (2000), 11

A traumatic brain injury may have a great impact on the family as a whole and may include changes in the family's organizational structure, communication patterns, or balance of family needs. In spite of ... [more ▼]

A traumatic brain injury may have a great impact on the family as a whole and may include changes in the family's organizational structure, communication patterns, or balance of family needs. In spite of this, treatment strategies for these problems are only slowly being recognized, resulting in either family reactions being inadequately addressed in rehabilitative programs, or treatment being approached from a family support perspective and not from a family therapy perspective. The aim of the following paper is to illustrate how family therapeutical approaches can be used in treating families of individuals with brain injury, in particular, structural interventions. Clinical examples will be presented where structural interventions were utilized with brain injury patients and their families. Other inverventional approaches from family therapy will also be mentioned. [less ▲]

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See detailIdentification et caractérisation partielle d'un gène de Fasciola hepatica d'intérêt diagnostique
Bossaert, K.; Martin-Alonzo, J. M.; Ruiz de Eguino, A. D. et al

in Annales de Médecine Vétérinaire (2000), 144

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See detailDéveloppement durable et organisation urbaine : le mot dʼordre de la ville compacte
Halleux, Jean-Marie ULg

in Cahiers de l'Urbanisme (Les) (2000), (30), 18-23

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See detailLe paradoxe du passage a l'acte: l'agressivité n'est pas la violence
Dozot, Jean-Paul; Triffaux, Jean-Marc ULg; Wauthy, Jacques ULg et al

in Revue des Hôpitaux de Jour Psychiatriques et des Thérapies Institutionnelles (2000), 2

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See detailNeuropsychologie de l'apprentissage implicte et de la mémoire procédurale
Meulemans, Thierry ULg

in Revue de Neuropsychologie (2000), 10(1), 129-157

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See detailCattle neosporosis in Belgium : a case-control study in dairy and beef cattle
De Meerscham, F.; Focant, C.; Boreux, R. et al

in International Journal for Parasitology (2000)

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See detailSensitivity analysis for the EPIK vulnerability assessment in a local karstic aquifer
Gogu, Radu Constantin; Dassargues, Alain ULg

in Hydrogeology Journal (2000), 8(3), 337-345

Applying the EPIK parametric method, a vulnerability assessment has been made for a small karstic groundwater system in southern Belgium. The aquifer is a karstified limestone of Devonian age. A map of ... [more ▼]

Applying the EPIK parametric method, a vulnerability assessment has been made for a small karstic groundwater system in southern Belgium. The aquifer is a karstified limestone of Devonian age. A map of intrinsic vulnerability of the aquifer and of the local water-supply system shows three vulnerability areas. A parameter-balance study and a sensitivity analysis were performed to evaluate the influence of single parameters on aquifer-vulnerability assessment using the EPIK method. This approach provides a methodology for the evaluation of vulnerability mapping and for more reliable interpretation of vulnerability indices for karst groundwater resources. [less ▲]

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See detailThe relationships between episodic memory, working memory, and executive functions: The contribution of the prefrontal cortex
Van der Linden, Martial ULg; Meulemans, Thierry ULg; Marczewski, Philippe et al

in Psychologica Belgica (2000), 40(4), 275-297

Discusses the neurophysiological functions of the prefrontal cortex related to memory processes. Functional brain imaging studies have revealed that distinct regions of the prefrontal cortex are engaged ... [more ▼]

Discusses the neurophysiological functions of the prefrontal cortex related to memory processes. Functional brain imaging studies have revealed that distinct regions of the prefrontal cortex are engaged in episodic memory operations, with some regions apparently part of multiple networks subserving different memory abilities. The prefrontal cortex is also involved in shifting processes. Working memory processes within the dorsolateral and ventrolateral frontal cortex are organized according to the type of processing required rather than the nature of the information being processed. The binding of contextual information, both incidentally and intentionally, is the most crucial process involved in episodic memory. Inhibition control involves not only bilateral prefrontal areas, but also posterior regions and subcortical structures, but the specific role of the cerebral areas is not clear at present. [less ▲]

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See detailAmphipods of a stony beach in the maritime Antarctic
Jazdzewski, Krzystov; De Broyer, Claude; Pudlarz, M. et al

in Polish Archives for Hydrobiology (2000), 47

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See detailCharacterization of embryos derived from calf oocytes: kinetics of cleavage, cell allocation to inner cell mass, and trophectoderm and lipid metabolism.
Majerus, V.; Lequarré, Anne-Sophie ULg; Ferguson, E. M. et al

in Molecular Reproduction and Development (2000), 57(4), 346-52

Embryos derived from calf oocytes were compared with adult cow oocyte-derived embryos (1) by studying the kinetics of embryo development using time-lapse cinematography (2) by evaluating the ratio between ... [more ▼]

Embryos derived from calf oocytes were compared with adult cow oocyte-derived embryos (1) by studying the kinetics of embryo development using time-lapse cinematography (2) by evaluating the ratio between inner cell mass (ICM) and trophectoderm (TE) cells in blastocysts (3) by measuring the triglyceride content of the blastocysts. The rate of calf oocyte-derived embryos reaching the blastocyst stage was reduced (26 vs. 46% for adult derived embryos). Calf oocyte-derived embryos preferably arrested their development before the 9-cell stage. Those that developed into blastocysts had cleaved earlier to reach the 2-cell or 3-cell stages than embryos that arrested before the 9-cell stage. The 9-cell stage tended to appear later in calf oocyte-derived embryo that reached the blastocyst stage than in adult-derived embryos. This difference became significant at the morula stage. Accordingly, the fourth cell cycle duration was longer for calf oocyte-derived embryos. Day 8 blastocysts from both sources had similar total cell numbers (calf: 89 +/- 20; cow: 100 +/- 30) and cell distribution between TE and ICM. The triglyceride content of day 7 blastocysts was similar for both sources (64 +/- 15 vs. 65 +/- 6 ng/embryo, respectively). In conclusion, calf oocyte-derived embryos are characterized by a higher rate of developmental arrest before the 9-cell stage and by a longer lag phase preceding the major onset of embryonic genome expression. These changes might be related to insufficient "capacitation" of the calf oocyte during follicular growth. Despite these differences, modifications in the quality of the resulting blastocysts were not detected. [less ▲]

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See detailPlacental growth hormone and IGF-I in a pregnant woman with Pit-1 deficiency
Verhaeghe, J.; Bougoussa, M.; Van Herck, E. et al

in Clinical Endocrinology (2000), 53(5), 645-647

The respective contributions of pituitary and placental GH to circulating IGF-I in pregnant women have not been well established. We measured the serum concentrations of placental growth hormone (PGH) and ... [more ▼]

The respective contributions of pituitary and placental GH to circulating IGF-I in pregnant women have not been well established. We measured the serum concentrations of placental growth hormone (PGH) and IGF-I in a woman with pit-1 deficiency before, during and after pregnancy, resulting in the birth of a healthy child (not pit-1 deficient). Both PGH and IGF-I concentrations were below the assay detection limit before and after pregnancy. During pregnancy, PGH and IGF-I levels increased steadily; the concentrations of PGH and IGF-I in late pregnancy were comparable with levels previously measured in normal pregnancies. PGH and IGF-I concentrations were strongly correlated throughout pregnancy (r = 0.90; P = 0.002). PGH was undetectable in cord serum, whilst the IGF-I concentration was within the normal range. The findings of this case study corroborate the notion that PGH is the prime regulator of maternal serum IGF-I during pregnancy. [less ▲]

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See detailLa réforme grégorienne et les tentatives de réforme du calendrier grégorien
Biémont, Emile ULg

in Bulletin de liaison du Département d'Etudes grecques, latines et Orientales de l'Université de Louvain (2000), 11

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See detailChemical profiles of Amblystegium riparium, Fontinalis antipyretica and Rhynchostegium riparioides in the Grand-Duchy of Luxembourg
Vanderpoorten, Alain ULg; Ector, L.; Hoffmann, L.

in Nova Hedwigia (2000), 71(1-2), 209-221

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See detailL'impact de l'introduction des contrats d'options sur la Bourse de Bruxelles
Corhay, Albert ULg; Tourani-Rad, Alireza

in Cahiers Economiques de Bruxelles (2000), (166), 109-130

L'objectif de cette étude est de déterminer l'impact de la création et de l'émission de contrats d'options sur les caractéristiques des actions de la Bourse de Bruxelles. Deux types d'analyse, l'analyse ... [more ▼]

L'objectif de cette étude est de déterminer l'impact de la création et de l'émission de contrats d'options sur les caractéristiques des actions de la Bourse de Bruxelles. Deux types d'analyse, l'analyse événementielle et l'analyse économétrique des séries chronologiques individuelles utilisant notamment un modèle GARCH, sont utilisés. Tous deux aboutissent à la même conclusion. Les résultats montrent qu'il n'existe pas de tendance générale commune à l'ensemble des titres pour ce qui concerne leur rendement et leur volatilité et que très peu de coefficients mesurant l'impact sur ces derniers sont statistiquement significatifs. Seul le volume de transaction des titres apparaît être affecté positivement par l'émission de contrats d'option. [less ▲]

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See detailAn automata-theoretic approach to branching-time model checking
Kupferman, Orna; Vardi, Moshe Y; Wolper, Pierre ULg

in Journal of the ACM (2000), 47(2), 312-360

Translating linear temporal logic formulas to automata has proven to be an effective approach for implementing linear-time model-checking, and for obtaining many extensions and improvements to this ... [more ▼]

Translating linear temporal logic formulas to automata has proven to be an effective approach for implementing linear-time model-checking, and for obtaining many extensions and improvements to this verification method. On the other hand, for branching temporal logic, automate-theoretic techniques have long been thought to introduce an exponential penalty, making them essentially useless for model-checking. Recently, Bernholtz and Grumberg [1993] have shown that this exponential penalty can be avoided, though they did not match the linear complexity of non-automata-theoretic algorithms. In this paper, we show that alternating tree automata are the key to a comprehensive automata-theoretic framework for branching temporal logics. Not only can they be used to obtain optimal decision procedures, as was shown by Muller ct al., but, as we show here, they also make it possible to derive optimal model-checking algorithms. Moreover, the simple combinatorial structure that emerges from the automata-theoretic approach opens up new possibilities for the implementation of branching-time model checking, and has enabled us to derive improved space complexity bounds for this long-standing problem. [less ▲]

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See detailEcoliers et apprentis-lecteurs : quelle est la motivation des enfants en première primaire ?
Hindryckx, Geneviève ULg; Lafontaine, Annette ULg; Schockert, C.

in Point sur la Recherche en Education (Le) (2000)

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See detailA four-parameter index of marrow dysplasia has predictive value for survival in myelodysplastic syndromes.
Tassin, Françoise ULg; Dewé, Walthère ULg; Schaaf, Nicole ULg et al

in Leukemia & Lymphoma (2000), 36(5-6), 485-96

Marrow dysplasia is a major characteristic of patients with myelodysplastic syndrome (MDS), along with marrow blastosis, cytopenia and cytogenetic anomalies. However, the impact of the degree of marrow ... [more ▼]

Marrow dysplasia is a major characteristic of patients with myelodysplastic syndrome (MDS), along with marrow blastosis, cytopenia and cytogenetic anomalies. However, the impact of the degree of marrow dysplasia on survival has not been fully assessed. In this retrospective analysis of 111 patients selected according to the IPSS criteria of MDS diagnosis, the presence or absence of 21 dysplasia characteristics recognizable in bone marrow smears stained by the May-Grunwald-Giemsa method was correlated with patient survival. Using Cox proportional hazards regression analysis, megaloblastosis (MEGALO), neutrophil agranularity (AGRAN) and hypogranularity (HYPOGRAN) were highly significant predictors (p < 0.005), and Pelger-Huet anomaly (PELGHUET) a significant predictor (p = 0.05), of patient survival. The regression analysis yielded a dysplasia-based risk index (DI) where DI = 1.26 MEGALO + 0.82 AGRAN - 1.08 HYPOGRAN + 0.45 PELGHUET. The two subgroups of 60 and 47 patients with DI < or = 0 and > 0 showed highly significant differences in median survivals (2.6 vs 1.1 yrs; p <0.0001). Multivariate analysis further showed that DI offered additional predictive power that was independent of that provided by the IPSS (p=0.002 and 0.001 respectively). Analysis of survival curves stratified for IPSS and DI showed that the additional predictive power offered by inclusion of the DI essentially concerned the IPSS low/INT-1 risk categories. Further stratification for age did not improve survival prediction. The data indicate that a set of 4 dysplasia parameters can offer some prediction for survival of MDS patients in addition to that provided by the IPSS. Further multicenter studies should aim at including some form of evaluation of the degree of dysplasia in prognostic systems. [less ▲]

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See detailProfil et épaisseur des mots : Kamau Brathwaite RêvHaïti
Pagnoulle, Christine ULg

in Palimpsestes (2000), 12

The article comments on the specifities of Brathwaite's use of language and typography and on the translator's attempt at retrieving them (the translator being also the author of the article).

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See detailPathological Findings in Two Fin Whales (Balaenoptera Physalus) with Evidence of Morbillivirus Infection
Jauniaux, Thierry ULg; Charlier, G.; Desmecht, M. et al

in Journal of Comparative Pathology (2000), 123(2-3, Aug-Oct), 198-201

Two immature female fin whales stranded on the Belgian and French coastlines, were examined post mortem. The main gross findings were massive parasitic infestation, associated with a large thrombus in one ... [more ▼]

Two immature female fin whales stranded on the Belgian and French coastlines, were examined post mortem. The main gross findings were massive parasitic infestation, associated with a large thrombus in one whale, and severe emaciation. Microscopical investigations revealed multinucleated syncytia with large intranuclear inclusion bodies in various tissues, and positive immunolabelling for morbillivirus antigens. Other evidence of morbillivirus infection was provided by the demonstration of specific viral structures in syncytia and in cell cultures, and the detection of neutralizing antibodies to canine distemper virus. To the authors>> knowledge, this is the first firm report of morbillivirus infection in baleen whales. [less ▲]

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