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See detailLong-term photometry of variables at ESO. III. The third data catalogue (1990-1992).
Manfroid, Jean ULg; Sterken, C.; Cunow, B. et al

in Astronomy and Astrophysics. Supplement Series (1995), 109

In this paper we present the third catalogue of photometric data in the Stroemgren system obtained during the period October 1990-January 1992 in the framework of the Long-Term Photometry of Variables ... [more ▼]

In this paper we present the third catalogue of photometric data in the Stroemgren system obtained during the period October 1990-January 1992 in the framework of the Long-Term Photometry of Variables (LTPV) program at the European Southern Observatory. The catalogue is available in computer readable form at the Centre de Donnees de Strasbourg. [less ▲]

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See detailElectronic properties of U2Ni2Sn
Kindo, Koichi; Fukushima, T.; Kumada, T. et al

in Journal of Magnetism & Magnetic Materials (1995), 140-144(2), 1369-1370

We report on the bulk electronic properties of U2Ni2Sn, which crystallizes in the tetragonal U3Si2 structure. Pronounced anomalies in the temperature dependencies of magnetic susceptibility, specific heat ... [more ▼]

We report on the bulk electronic properties of U2Ni2Sn, which crystallizes in the tetragonal U3Si2 structure. Pronounced anomalies in the temperature dependencies of magnetic susceptibility, specific heat and electrical resistivity indicate magnetic ordering below TN = 26 K. An antiferromagnetic ground state is corroborated by the occurrence of three metamagnetic transitions at about 30, 39 and 51 T in the field dependence of the magnetization. The lack of any saturation tendency in the highest field applied (57 T) may suggest further transition(s) to occur in even higher fields. [less ▲]

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See detailComment j'explore un patient hypertendu
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1995), 50(2), 91-92

Des examens complémentaires consitituent une étape importante de la prise en charge d'un patient hypertendu. Du bilan de base simple, peu coûteux et à appliquer à tous, aux examens paracliniques les plus ... [more ▼]

Des examens complémentaires consitituent une étape importante de la prise en charge d'un patient hypertendu. Du bilan de base simple, peu coûteux et à appliquer à tous, aux examens paracliniques les plus sophistiqués, la prescription nécessite cependant une personnalisation. II n'y a en effet pas une hypertension à explorer, mais des hypertendus, fort différents entre eux. Les examens à recommander vont cerner l'état actuel cardiaque, artériel et rénal ainsi que le profil de risque cardiovasculaire. Ils vont aussi rechercher une cause à l'élévation de pression si la clinique, l'anamnèse et quelques examens de laboratoire le suggèrent. [less ▲]

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See detailMacrofagos e factor a de necrose tumoral na necrolise epidermica toxica
Paquet, Philippe ULg; Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg et al

in Arquivos de Dermatologia (1995), 2

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular ... [more ▼]

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular inflamatorio varió dependiendo del estado de la enfermedad. La principal característica constante fue la importante implicación de la línea monocito-macrófago, incluyendo dendrocitos factor XIIIa+ HLA-DR+ y macrófagos CD68+ Mac 387+, antes y durante la necrosis epidérmica. El número de linfocitos CD4+ y CD8+ era comparativamente reducido. Ello se asociaba con un denso marcaje para el factor de necrosis tumoral alfa en la epidermis. CONCLUSIONES: Las células de estirpe monocito-macrófago superan en nùmero ampliamente a los linfocitos en las lesiones de la necrólisis epidérmica tóxica. El factor de necrosis tumoral alfa es problablemente una de las citocinas principales responsables de la necrosis. [less ▲]

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See detailAmpd, Essential for Both Beta-Lactamase Regulation and Cell Wall Recycling, Is a Novel Cytosolic N-Acetylmuramyl-L-Alanine Amidase
Jacobs, Christine ULg; Joris, Bernard ULg; Jamin, M. et al

in Molecular Microbiology (1995), 15(3), 553-9

In enterobacteria, the ampD gene encodes a cytosolic protein which acts as a negative regulator of beta-lactamase expression. It is shown here that the AmpD protein is a novel N-acetylmuramyl-L-alanine ... [more ▼]

In enterobacteria, the ampD gene encodes a cytosolic protein which acts as a negative regulator of beta-lactamase expression. It is shown here that the AmpD protein is a novel N-acetylmuramyl-L-alanine amidase (E.C.3.5.1.28) participating in the intracellular recycling of peptidoglycan fragments. Surprisingly, AmpD exhibits an exclusive specificity for substrates containing anhydro muramic acid. This anhydro bond is mainly found in the peptidoglycan degradation products formed by the periplasmic lytic transglycosylases and thus might behave as a 'recycling tag' allowing the enzyme to distinguish these fragments from the newly synthesized peptidoglycan precursors. The AmpD substrate (or substrates) which accumulates in the absence of the corresponding enzymatic activity acts as an intracellular positive effector for beta-lactamase expression and might represent an element of a communication network between the chromosome and the cell wall peptidoglycan. [less ▲]

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See detailLe cas clinique du mois. A propos d'un cas de sécrétion ectopique d'ACTH
Biessaux, Yves ULg; Paquot, Nicolas ULg; Scheen, A. J. et al

in Revue Médicale de Liège (1995), 50(2), 55-6

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See detailMagnetic kinetic growth-models
Ausloos, Marcel ULg; Vandewalle, Nicolas ULg; Cloots, Rudi ULg

in Journal of Magnetism & Magnetic Materials (1995), 140(Part 3), 2185-2186

Magnetic kinetic growth models are kinetic growth model(s), like the Eden or the DLA models, but allow for the growth to have an extra degree of freedom (a 'spin') which can be coupled to an external ... [more ▼]

Magnetic kinetic growth models are kinetic growth model(s), like the Eden or the DLA models, but allow for the growth to have an extra degree of freedom (a 'spin') which can be coupled to an external field. Two-dimensional simulations show interesting morphologies and parameter dependences. [less ▲]

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See detailThe role of agrometeorological data bases and software in agrometeorological training in developing countries.
Tychon, Bernard ULg; Tonnard, Victor

in FAO Agrometeorology series (1995), 13

The paper covers a Belgian agrometeorological training course intended for francophone students from developing countries who have completed a minimum of four years training in agrometeorology. Today ... [more ▼]

The paper covers a Belgian agrometeorological training course intended for francophone students from developing countries who have completed a minimum of four years training in agrometeorology. Today, many of our students are heads of agrometeorological departments and divisions. THey are interested in everything that could promote agrometeorological methods to preserve food security and the natural resources of their country. During the past few years, the students have been trained in using microcomputers and solving simple agro-meteorological problems as part of the course. The results obtained so far can now be evaluated, since the microcomputer training began a few years ago; some comments on the future development of this approach are presented. [less ▲]

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See detailSimulated growth and microstructure of DyBa2Cu3O7-X with and without Dy2BaCUO5 addition
Vandewalle, Nicolas ULg; Cloots, Rudi ULg; Ausloos, Marcel ULg

in Journal of Materials Research (1995), 10(2), 268-273

We present optical observations of magnetically melt-textured DyBa2Cu307-x with and without 20 wt. % excess of Dy2BaCu05. From these observations, we propose some kinetic mechanism of the growth of 123 ... [more ▼]

We present optical observations of magnetically melt-textured DyBa2Cu307-x with and without 20 wt. % excess of Dy2BaCu05. From these observations, we propose some kinetic mechanism of the growth of 123 compounds. Kinetic processes can simulated on computers. Two (very) simple models derived from the well-known Eden model are presented. They simulate the growth of the grain front. The simulated patterns agree with the observations. The microstructure of such materials cannot be explained by thermodynamic and chemical considerations alone, but explanations must include the kinetics of the growth front as well. From our observations, we conclude that the growth probability ratios g(110)/g(100)/g(001) are of the order of 10 and 50, respectively. [less ▲]

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See detailSpecificity and Sensitivity of Temporalis Es2 Measurements in the Diagnosis of Chronic Primary Headaches
Wang, W.; De Pasqua, Victor ULg; Gérard, P. et al

in Headache (1995), 35(2), 85-8

We have evaluated the specificity and sensitivity of temporalis ES2 measurements for the diagnosis of primary headaches. Ninety-four outpatients diagnosed according to IHS criteria were prospectively ... [more ▼]

We have evaluated the specificity and sensitivity of temporalis ES2 measurements for the diagnosis of primary headaches. Ninety-four outpatients diagnosed according to IHS criteria were prospectively included: 25 had chronic tension-type headache (code 2.2.), 15 episodic tension-type headache (code 2.1.), 20 migraine without aura (code 1.1.) and 34 chronic daily headaches with daily analgesics/ergotamine abuse (code 8.2.). In chronic tension-type, the sensitivity of the ES2 test was 84% at the 0.1 and the 0.5 Hz, but only 56% at the 2Hz stimulation rates. Its specificity was 100% at 0.1Hz, 90% at 0.5Hz and 95% at 2Hz compared to migraine; positive predictive values were at similar levels. Sensitivity of ES2 at 0.1 Hz was 67% in episodic tension-type headache, but its positive predictive value versus migraine was excellent. Comparing chronic tension-type headache and analgesic abusers, the specificity and positive predictive value of the ES2 test for diagnosing chronic tension-type headache were less satisfactory (60%) while the negative predictive values, however, remained good (83% at 0.1Hz). The results confirm that the temporalis ES2 test has a higher diagnostic sensitivity in chronic and episodic tension-type headache, but that it has a high negative predictive value for both types of tension-type headache compared to other primary headaches. For diagnostic purposes, the 0.1Hz stimulation rate seems optimal. The 2Hz stimulation rate is the least sensitive, although it may induce total disappearance of ES2 in up to 40% of patients. ES2 is of limited usefulness for separating chronic tension-type headache and chronic drug-abuse headache, possibly because the latter group comprises both tension-type headache and migraine patients. [less ▲]

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See detailPeroxidase-Catalysed Oxidation of Different Dibenzazepine Derivatives
Liégeois, Jean-François ULg; Rogister, F.; Delarge, J. et al

in Archiv der Pharmazie (1995), 328(2), 109-12

According to a recent hypothesis suggesting the potential role of free radical formation in the clozapine-induced agranulocytosis, we have evaluated the susceptibility to the peroxidase-mediated oxidation ... [more ▼]

According to a recent hypothesis suggesting the potential role of free radical formation in the clozapine-induced agranulocytosis, we have evaluated the susceptibility to the peroxidase-mediated oxidation of different dibenzazepine analogues. On the one hand, compounds with an arylamine group such as clozapine or isoclozapine present a high reactivity in the horseradish peroxidase or myeloperoxidase systems and, on the other hand, fluperlapine, though known to induce agranulocytosis, and other dibenzothiazepine and dibenzoxazepine derivatives appear insensitive to oxidation. Consequently, among tricyclic derivatives, the way of diaryloxa- and diarylthiazepine compounds could be an alternative for the development of safer drugs such as antipsychotics. [less ▲]

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See detailMagnetism in U2T2X compounds
Havela, Ladislav; Sechovsky, Vladimir; Svoboda, P. et al

in Journal of Magnetism & Magnetic Materials (1995), 140-144(2), 1367-1368

Magnetic and other electronic properties are presented for the U2T2X compounds (T = late transition metal, X = Sn or In), that crystallize in the tetragonal U3Si2-type structure. They show the formation ... [more ▼]

Magnetic and other electronic properties are presented for the U2T2X compounds (T = late transition metal, X = Sn or In), that crystallize in the tetragonal U3Si2-type structure. They show the formation of 5f magnetic moments and antiferromagnetic ordering in compounds where weak 5f-d hybridization is expected. Near the onset of magnetic ordering strongly enhanced γ-values are found. Neutron-diffraction experiments on U2Pd2Sn and U2Pd2In point to a connection between the mutual coordination of U atoms and the type of magnetic anisotropy [less ▲]

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See detailContribution of Mutant Analysis to the Understanding of Enzyme Catalysis: The Case of Class a Beta-Lactamases
Matagne, André ULg; Frère, Jean-Marie ULg

in Biochimica et Biophysica Acta (1995), 1246(2), 109-27

Class A beta-lactamases represent a family of well studied enzymes. They are responsible for many antibiotic resistance phenomena and thus for numerous failures in clinical chemotherapy. Despite the facts ... [more ▼]

Class A beta-lactamases represent a family of well studied enzymes. They are responsible for many antibiotic resistance phenomena and thus for numerous failures in clinical chemotherapy. Despite the facts that five structures are known at high resolution and that detailed analyses of enzymes modified by site-directed mutagenesis have been performed, their exact catalytic mechanism remains controversial. This review attempts to summarize and to discuss the many available data. [less ▲]

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See detailSimulation of Human B-Lymphocyte Proliferation by Agm-1470, a Potent Inhibitor of Angiogenesis
Antoine, Nadine ULg; Bours, Vincent ULg; Heinen, Ernst ULg et al

in Journal of the National Cancer Institute (1995), 87(2), 136-9

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See detailLes infections cutanées dues à l'herpès
Nikkels, Arjen ULg

in Actualités Médicales Belges (1995), 8(450),

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See detailSynthesis and Processing of Bovine Herpesvirus-1 Glycoprotein H
Baranowski, Eric; Dubuisson, Jean; van Drunen Little-van den Hurk, Sylvia et al

in Virology (1995), 206(1), 651-4

The translation product of the bovine herpesvirus-1 (BHV-1) gH gene was identified and characterized. Synthetic peptides were used to generate specific antisera and a glycoprotein of 108K was precipitated ... [more ▼]

The translation product of the bovine herpesvirus-1 (BHV-1) gH gene was identified and characterized. Synthetic peptides were used to generate specific antisera and a glycoprotein of 108K was precipitated by one of the antisera. Cross-immunoprecipitations with monoclonal antibodies to BHV-1 glycoprotein gp108 and the anti-gH peptide antiserum demonstrated that gp108 is the translation product of the gH open reading frame. Glycoprotein gH synthesis and intracellular processing was analyzed in infected Madin-Darby bovine kidney cells using anti-gp 108 monoclonal antibodies. Glycoprotein gH is expressed as a beta-gamma protein and could be detected by radioimmunoprecipitation as early as 2 hr postinfection. Cotranslational N-glycosylation of gH is essential for the recognition by monoclonal antibodies, suggesting that N-linked glycans are involved in protein folding or that they are targets for most of monoclonal antibodies used in this study. [less ▲]

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See detailIncreased Expression of Osteonectin and Osteopontin, Two Bone Matrix Proteins, in Human Breast Cancer
Bellahcene, Akeila ULg; Castronovo, Vincenzo ULg

in American Journal of Pathology (1995), 146(1), 95-100

Microcalcifications are a common phenomenon associated with breast cancer and are often the only mammographic sign of a malignant breast disease. Although microcalcifications are not restricted to breast ... [more ▼]

Microcalcifications are a common phenomenon associated with breast cancer and are often the only mammographic sign of a malignant breast disease. Although microcalcifications are not restricted to breast cancer and can be also associated with benign lesions, it is noteworthy that they are composed exclusively of hydroxyapatite in breast carcinoma. Hydroxyapatite is the bone-associated phosphocalcic crystal the deposition of which in bone tissue requires the coordinated expression of several molecules such as osteonectin (OSN) and osteopontin (OPN), synthesized by cells of the osteoblastic lineage. In this study, we evaluated the expression of these two bone matrix proteins, using an immunoperoxidase technique and specific antibodies, in 79 breast lesions including 28 benign and 51 cancerous specimens. We found that normal mammary tissue associated with the lesions examined expressed generally undetectable or lightly detectable (0 or 1+) amounts of OSN and OPN (92 and 81%, respectively). Benign breast lesions, including fibroadenoma and fibrocystic dysplasia, were generally weakly stained (0 or 1+) with both anti-OSN and anti-OPN antibodies (96.4 and 60.7%, respectively). Interestingly, the majority of both in situ and invasive breast carcinoma lesions showed a strong expression (2+ or 3+) for OSN or OPN (74.5 and 84.3%, respectively). High expression of these two bone matrix proteins was associated with frequent microcalcification deposition in the lesion. This study is the first extensive study of OSN and OPN expression in mammary cancers. Our data suggest that OSN and OPN could play a role in the formation of ectopic microcalcifications often associated with breast cancer. It is also tempting to speculate that the expression of these two glycoproteins by breast cancer cells play a role in the preferred bone homing of breast metastases. [less ▲]

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See detailHypercholestérolémie modérée et coronaropathies: étude MAAS et étude 4S
Martinez, Christophe ULg; Legrand, Victor ULg; Kulbertus, Henri ULg

in Revue Médicale de Liège (1995), 50(1), 35-40

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See detailKinetic Study of Interaction between Brl 42715, Beta-Lactamases, and D-Alanyl-D-Alanine Peptidases
Matagne, André ULg; Ledent, Philippe; Monnaie, Didier et al

in Antimicrobial Agents and Chemotherapy (1995), 39(1), 227-31

A detailed kinetic study of the interactions between BRL 42715, a beta-lactamase-inhibiting penem, and various beta-lactamases (EC 3.5.2.6) and D-alanyl-D-alanine peptidases (DD-peptidases, EC 3.4.16.4 ... [more ▼]

A detailed kinetic study of the interactions between BRL 42715, a beta-lactamase-inhibiting penem, and various beta-lactamases (EC 3.5.2.6) and D-alanyl-D-alanine peptidases (DD-peptidases, EC 3.4.16.4) is presented. The compound was a very efficient inactivator of all active-site serine beta-lactamases but was hydrolyzed by the class B, Zn(2+)-containing enzymes, with very different kcat values. Inactivation of the Streptomyces sp. strain R61 extracellular DD-peptidase was not observed, and the Actinomadura sp. strain R39 DD-peptidase exhibited a low level of sensitivity to the compound. [less ▲]

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See detailMagnetic diffusion-limited aggregation
Vandewalle, Nicolas ULg; Ausloos, Marcel ULg

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1995), 51(1), 597-603

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See detailLe romancier en projet. Quand André Gide étudiait Georges Simenon
Denis, Benoît ULg

in Bulletin des amis d'André Gide (1995), XXVIII(105), 53-70

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See detailInvestigation of the Relationship between Osteoporosis and the Collagenase Gene by Means of Polymorphism of the 5'upstream Region of This Gene
Thiry-Blaise, L. M.; Taquet, A. N.; Reginster, Jean-Yves ULg et al

in Calcified Tissue International (1995), 56

Osteoporosis is a slowly progressing disease resulting from an imbalance between bone accretion and degradation. As interstitial collagenase is a key enzyme in the degradation of bone matrix, we ... [more ▼]

Osteoporosis is a slowly progressing disease resulting from an imbalance between bone accretion and degradation. As interstitial collagenase is a key enzyme in the degradation of bone matrix, we investigated a possible relationship between the collagenase gene and osteoporosis. Analysis of an amplified genomic DNA fragment from -524 to +52 by denaturing gradient gel electrophoresis and sequencing allowed us to detect three dimorphic sites upstream of base -300, one of them leading to a BanI restriction site. None of the sites could be directly associated with osteoporosis. The allele frequencies of the three dimorphic sites were estimated. The interallelic ratios were high, thus providing new useful genetic markers for linkage analysis. When comparing these ratios in osteoporotic and nonosteoporotic subjects, no significant differences could be observed. [less ▲]

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See detailBasic Research and Policy Making for the Development of Vessel Traffic Management Information Systems
Marchal, Jean ULg

in Basic Research and Policy Making (1995)

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See detailA Prenatal Trisomy 21 Screening Program Using Alpha-Fetoprotein, Human Chorionic Gonadotropin, and Free Estriol Assays on Maternal Dried Blood
Verloes, Alain ULg; Schoos, Roland ULg; Herens, Christian ULg et al

in American Journal of Obstetrics and Gynecology (1995), 172(1, Pt 1), 167-74

OBJECTIVE: The feasibility of large-scale Down syndrome maternal screening with dried blood samples and nonradioactive methods was examined. STUDY DESIGN: A prospective observation study was performed on ... [more ▼]

OBJECTIVE: The feasibility of large-scale Down syndrome maternal screening with dried blood samples and nonradioactive methods was examined. STUDY DESIGN: A prospective observation study was performed on a nonselected population of 11,241 pregnant women sampled between January 1991 and September 1992, between 14 and 24 weeks' gestation (ultrasonographic scanning available for 91.6%), through a multicenter collaborative network. Enzyme-linked immunosorbent assays for alpha-fetoprotein, human chorionic gonadotropin, and free estriol were performed on dried blood samples. Risk determination was made with an in-house software implementing the multivariate gaussian log likelihood method. RESULTS: A total of 10,450 samples were eligible for the study. Mean age at term was 27.9 years. A total of 6.84% of the patients were > or = 35 years old with a prior risk of trisomy 21 > 1:350. The general positive rate of our sample was 8.15%. After calculation 31.7% with prior risk > 1:350 were still in the high-risk group; 6.36% of the low-risk group were found to be at high risk for Down syndrome. Fifteen trisomic pregnancies were observed, of which 11 had a calculated risk higher than the selected cutoff value (1:350). The overall detection rate was 73%, specificity was 92%, and positive predictive power was 1.2%. CONCLUSION: Our pilot study has shown performances within the range of conventional serum screening programs. Dried blood assays are a handy alternative to serum assays. Blot paper cards represent a simple method of sampling, well fitted for large population screening. Combined with nonradioactive methods, this method appears to be both low cost and effective. The current work apparently is the first large-scale Down screening program performed with dried blood. [less ▲]

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See detailTamoxifen and its active metabolite inhibit growth of estrogen receptor-negative MDA-MB-435 cells
Charlier, Corinne ULg; Chariot, Alain ULg; Antoine, Nadine ULg et al

in Biochemical Pharmacology (1995), 49

Tamoxifen (TAM), the non-steroidal anti-estrogen most widely administered to breast cancer patients, acts, at least in part, by competing with estrogen receptors (ER). However, the existence of an ... [more ▼]

Tamoxifen (TAM), the non-steroidal anti-estrogen most widely administered to breast cancer patients, acts, at least in part, by competing with estrogen receptors (ER). However, the existence of an alternative mechanism of action for this drug is supported by the clinical observations that: (a) 30% of patients with ER-negative cancer cells respond to TAM, and (b) 30% of patients with ER-positive cancer cells are not sensitive to this anti-estrogen. In this study, we observed that growth of the human ER-negative breast cancer cell line MDA-MB-435 was inhibited by TAM and 4-hydroxytamoxifen (4OH-TAM) in a concentration-dependent fashion. Both monoclonal enzymoimmunoassay and Dextran Charcoal Coated Scatchard radioimmunoassay analysis demonstrated that this MDA-MB-435 cell line does not express ER. The absence of ER in MDA-MB-435 cells was also demonstrated at the mRNA level by both northern blot hybridization and reverse transcription-polymerase chain reaction techniques. MDA-MB-435 cell proliferation was not affected by 17 beta-estradiol or by the pure anti-estrogen ICI 164384, further demonstrating that the observed effects of TAM and its active metabolite on the proliferation of MDA-MB-435 cells were due to an ER-independent mechanism, yet to be identified. MDA-MB-435 thus appears to be a promising original model for the study of the alternative ER-independent mechanisms of action of TAM. [less ▲]

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See detailComment je traite ... un patient avec une insuffisance cardiaque légère ou modérée?
Pierard, Luc ULg

in Revue Médicale de Liège (1995), 50(1), 5-6

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See detailA magnetic resonance imaging approach for the diagnosis of a triplet cornual pregnancy.
Bassil, Salim; Gordts, Stéphane; NISOLLE, Michelle ULg et al

in Fertility and Sterility (1995), 64(5), 1029-31

Objectives: To describe a rare case of triplet cornual pregnancy after IVF-ET and to assess the role of magnetic resonance imaging (MRI) for early diagnosis. DESIGN: Case report. SETTING: Infertility and ... [more ▼]

Objectives: To describe a rare case of triplet cornual pregnancy after IVF-ET and to assess the role of magnetic resonance imaging (MRI) for early diagnosis. DESIGN: Case report. SETTING: Infertility and IVF Unit, in an university medical center. PATIENT: A 31-year-old healthy patient with a 3-year history of primary male infertility. INTERVENTION: Standard IVF-ET treatment cycle, using a GnRH-agonist (long protocol) and hMG for ovarian stimulation. RESULTS: A cornual triplet pregnancy is described with the approach for the diagnosis. Magnetic resonance imaging was complementary to endovaginal sonography for early diagnosis and permitted a timed conservative management. CONCLUSIONS: When transvaginal ultrasound findings did not provide an accurate location of the pregnancy, MRI was indicated to confirm the diagnosis. [less ▲]

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See detailGrowth hormone, insulin-like growth factor-I and their plasma binding proteins in different cattle breeds.
Renaville, Robert ULg; Massart, Serge; Shojae, D. et al

in Zootecnica e Nutrizione Animale (1995), 21(2),

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See detailNetherton’s syndrome in two sisters. A ten year experience of therapy with retinoids
Groves, S.; Dezfoulian, Bita ULg; Bonardeaux, Ch et al

in Journal of the European Academy of Dermatology & Venereology (1995)

Netherton’s syndrome is a recessive autosomal disease associating ichthyosiform dermatosis, hair dysplasia and systemic involvement. (Netherton, 1958, Arch. Dermatol., Vol. 78,483-487). We report the ... [more ▼]

Netherton’s syndrome is a recessive autosomal disease associating ichthyosiform dermatosis, hair dysplasia and systemic involvement. (Netherton, 1958, Arch. Dermatol., Vol. 78,483-487). We report the observation of two sisters who present the complete form of Netherton’s syndrome. Both patients were treated with retinoids for more than ten years. [less ▲]

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See detailRecent advances in the chemistry of potassium channel openers
Pirotte, Bernard ULg; Fontaine, J.; Lebrun, P.

in Current Medicinal Chemistry (1995), 2

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See detailAneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees.
VERLOES, Alain ULg; SakalihasanN, Natzi ULg; Koulischer, Lucien ULg et al

in Journal of Vascular Surgery (1995), 21(4), 646-55

PURPOSE: Familial clustering of abdominal aortic aneurysm was first noticed in 1977. METHODS: Through questionnaire and phone inquiry, familial data on 324 probands with abdominal aortic aneurysms allowed ... [more ▼]

PURPOSE: Familial clustering of abdominal aortic aneurysm was first noticed in 1977. METHODS: Through questionnaire and phone inquiry, familial data on 324 probands with abdominal aortic aneurysms allowed the establishment of 313 multigenerational pedigrees including 39 with multiple affected patients. RESULTS: There were 276 sporadic cases (264 men, 12 women); 81 cases belonged to multiplex pedigrees (76 men; 5 women). We compared familial and sporadic male cases; the ages at diagnosis were 64.1 +/- 7.9 years and 66.0 +/- 7.3 years (p < 0.05), respectively, the ages at rupture were 65.4 +/- 6.6 years and 75.2 +/- 8.6 years (p < 0.001), and the rupture rate was 32.4% and 8.7% (p < 0.001). Survival curves were computed. Relative risk for male siblings of a male patient was 18. We performed a segregation analysis with the mixed model, the most likely explanation for occurrence of abdominal aortic aneurysm in our families was a single gene effect showing dominant inheritance. The frequency of the morbid allele was 1:250, and its age-related penetrance was not higher than 0.4. CONCLUSION: This analysis indicates the preeminence of genetic factors on multifactorial/environmental effects of the pathogenesis of abdominal aortic aneurysm. [less ▲]

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See detailFast Routine Production of L-[11C-methyl]methionine with Al2O3KF
Schmitz, Frédéric; Plenevaux, Alain ULg; Del-Fiore, Guy et al

in Applied Radiation & Isotopes (1995), 46(9), 893-897

No-carrier-added (nca) L-[11C-methyl]methionine was prepared via the very fast S-alkylation of L-homocysteine adsorbed on AI203/KF with [11C]iodomethane at room temperature in ethanol. The alkylation was ... [more ▼]

No-carrier-added (nca) L-[11C-methyl]methionine was prepared via the very fast S-alkylation of L-homocysteine adsorbed on AI203/KF with [11C]iodomethane at room temperature in ethanol. The alkylation was realized with a radiochemical yield of 94 +/- 4% EOB (n = 20). More than 90% (n = 20) of the precursor L-homocysteine remained adsorbed on the solid support and was eliminated by a simple filtration. After reaction, neither racemization nor by-product were detected. The purification process was thus limited to a C18 Sep-Pak followed by an alumina Sep-Pak. The radiochemical purity measured on the final solution was shown to be > 99%. The only chemical contaminant was L-homocysteine (+ 10 µg). With this new technique, L-[11C-methyl]methionine was ready for injection within 10 min from [11C]CO2 with a specific activity ranging around 37 + 5.6 GBq (1 +/- 0.15 Ci)//tmol EOB. Through this procedure L-[11C-methyl]methionine can be prepared without preparative HPLC purification, This is an important simplification for the fast routine production of one of the most widely used radiopharmaceutical compounds for PET. [less ▲]

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See detailUtilisation des matières grasses chez les bovins à l'engraissement
Clinquart, Antoine ULg; Micol, Didier; Brundseaux, Christophe et al

in Productions Animales (1995), 8

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See detailN2-cyano-N1-isopropyl-N3-[4-(3-methylphenylamino)-3-pyridylsulfonyl]guanidine
Dupont, L.; Masereel, B.; De Tullio, Pascal ULg et al

in Acta Crystallographica (1995), C51

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See detailThe effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine.
Tfelt-Hansen, P.; Henry, P.; Mulder, L. J. et al

in Lancet (1995), 346(8980), 923-6

Aspirin is commonly used to treat migraine attacks, although sumatriptan, a much more expensive treatment, is also effective. We compared a combination of lysine acetylsalicylate (equivalent to 900 mg ... [more ▼]

Aspirin is commonly used to treat migraine attacks, although sumatriptan, a much more expensive treatment, is also effective. We compared a combination of lysine acetylsalicylate (equivalent to 900 mg aspirin) and 10 mg metoclopramide (LAS+MTC) with oral sumatriptan (100 mg) and placebo in 421 patients with migraine. LAS+MTC was as effective as sumatriptan with a decrease of headache from severe or moderate to mild or none of 57% and 53%, respectively, for the first migraine attack treated. Both treatments were better than placebo (success rate 24%, p < 0.0001). LAS+MTC was significantly more effective in the treatment of nausea than sumatriptan (p < 0.0001) and was better tolerated (adverse events in 18% and 28%, respectively, p < 0.05). LAS+MTC is as effective as sumatriptan in the treatment of migraine attacks. It is also much cheaper. [less ▲]

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See detailValve Replacement for Acute Left Heart Endocarditis
Detry, Olivier ULg; Defraigne, Jean-Olivier ULg; Limet, Raymond ULg

in Cardiovascular Surgery (1995), 3(5), 529-35

Between January 1982 and June 1993, 66 patients (48 men and 18 women of mean (range) age 50 (21-77) years) underwent valve replacement for acute infective endocarditis. There were 45 aortic valve and 17 ... [more ▼]

Between January 1982 and June 1993, 66 patients (48 men and 18 women of mean (range) age 50 (21-77) years) underwent valve replacement for acute infective endocarditis. There were 45 aortic valve and 17 mitral valve infections. Four patients had bivalvular involvement. Fifty-three patients suffered from native valve endocarditis, with underlying valvular lesions documented for 31 patients. Staphylococci and Streptococci spp. were responsible for 68% of infection, and 20% of blood and valve cultures were negative. Refractory congestive heart failure was the leading surgical indication in 86% of patients. The mean follow-up period was 44 months. The perioperative mortality rate was 6%. Actuarial survival rates were 88.5% at 1 year and 83% at 3 years. No early recurrence of infection was noted. Six patients (9%) needed reoperation. Satisfactory results confirm that early surgical management should be considered in patients with complicated infective endocarditis. [less ▲]

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See detailHandling infinite temporal data
Kabanza, Froduald; Stevenne, Jean-Marc; Wolper, Pierre ULg

in Journal of Computer & System Sciences (1995), 51(1), 3--17

In this paper, we present a powerful framework for describing, storing, and reasoning about infinite temporal information. This framework is an extension of classical relational databases. It represents ... [more ▼]

In this paper, we present a powerful framework for describing, storing, and reasoning about infinite temporal information. This framework is an extension of classical relational databases. It represents infinite temporal information by generalized tuples defined by linear repeating points and constraints on these points. We characterize the expressiveness of these generalized relations in terms of predicates definable in Presburger arithmetic. Next, we prove that relations formed from generalized tuples are closed under the operations of relational algebra and provide complexity results for the evaluation of first-order queries. [less ▲]

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See detailLa transmission du chant chez le Pinson des arbres (Fringilla c. coelebs) : phase sensible et rôle des tuteurs chez les oiseaux captifs.
Metzmacher, Maxime ULg

in Alauda (1995), 63

Learning plays a key role (Thorpe 1954) in the way song pattern develops in the Chaffinch. In experiments conducted and related here by Léon Hakin, the rearing of young Chaffinches in the presence of ... [more ▼]

Learning plays a key role (Thorpe 1954) in the way song pattern develops in the Chaffinch. In experiments conducted and related here by Léon Hakin, the rearing of young Chaffinches in the presence of adults of the same species suggests that : - learning of song can be relatively precise ; the young imitate the song(s) heard from its « teachers » during this period. This confirms experiments done by other researchers under different conditions (Slater & Ince 1982, Thielcke & Krome 1989). Some differences may however occur, particurlarly the form of the reproduced syllabes and their rythm of emision. - during its second calendar year, a bird placed in a new sound atmosphere can acquire new phrases and, apparently, forget its previous repertory. - certain young birds build up their repertory by coping phrases from different individuals and copy many of them for fixing the tempo of their song. The aim of the discussion is to find the characteristics of the sensitive period, the importance of social interactions on the process of song learning, the building of a repertory and the formation of dialects. In the last two phenomena, a process of dynamic and selective restructuration appears to be implied. [less ▲]

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See detailUtilisation de la paille dans des rations d'engraissement: ingestion, dynamique de la digestion et cinétique de dégradabilité dans le rumen
Mayombo, Asangule Pierre; Van Eenaeme, Christian ULg; Gauthier, Sabine et al

in Annales de Zootechnie (1995), 44

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See detailInfection respiratoire équine à Bordetella bronchiseptica
Vandevenne, S.; Caudron, I.; Serteyn, Didier ULg et al

in Annales de Médecine Vétérinaire (1995), 139

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See detailToxicité potentielle et utilisation pratique du méthotrexate dans la polyarthrite rhumatoïde
Kaye, O.; Ribbens, Clio ULg; Hauwaert, Christian ULg et al

in Médecine et Hygiène (1995)

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See detailDisparités au sein du système éducatif en Communauté française de Belgique
Lafontaine, Dominique ULg

in Eduquer et former. Théories et pratiques (1995), 7

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See detailComment explorer la sensibilite a l'insuline chez l'homme?
Scheen, André ULg; Paquot, Nicolas ULg; Letiexhe, Michel ULg et al

in Annales d'Endocrinologie (1995), 56(5), 523-30

The two most widely used methods for studying insulin sensitivity in man are the euglycaemic hyperinsulinaemic clamp and the intravenous glucose tolerance test with minimal model assessment. The glucose ... [more ▼]

The two most widely used methods for studying insulin sensitivity in man are the euglycaemic hyperinsulinaemic clamp and the intravenous glucose tolerance test with minimal model assessment. The glucose clamp is the reference method, well validated and easy to interpret, which allows various extensions to the basic experimental procedure in order to obtain more valuable information on the specific effects of insulin on the various aspects of glucose metabolism. However, it is time-consuming and labour-intensive. In contrast, the intravenous glucose tolerance test is easier to perform, but its interpretation is much more difficult and requires a modeling approach called the "minimal model". If the intravenous glucose tolerance test probably represents a good screening test, mainly on a population basis, the glucose clamp still remains the gold standard method to study insulin sensitivity in man. [less ▲]

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See detailInteractions between IL-1bêta, IL-6, IL-8 and LIF produced by human chondrocytes
Henrotin; Franchimont, P; Reginster, Jean-Yves ULg

in The Official EULAR Journal for Education and Information (1995), 24

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See detailMolecular cloning and characterization of a soluble inorganic pyrophosphatase in potato.
du Jardin, Patrick ULg; Rojas-Beltran, J.; Gebhardt, C. et al

in Plant Physiology (1995), 109(3), 853-60

A cDNA clone encoding a soluble inorganic pyrophosphatase (EC 3.6.1.1) of potato (Solanum tuberosum L.) was isolated by screening a developing tuber library with a heterologous probe. The central domain ... [more ▼]

A cDNA clone encoding a soluble inorganic pyrophosphatase (EC 3.6.1.1) of potato (Solanum tuberosum L.) was isolated by screening a developing tuber library with a heterologous probe. The central domain of the encoded polypeptide is nearly identical at the sequence level with its Arabidopsis homolog (J.J. Kieber and E.R. Signer [1991] Plant Mol Biol 16: 345-348). Computer-assisted analysis of the potato, Arabidopsis, and Escherichia coli soluble pyrophosphatases indicated a remarkably conserved organization of the hydrophobic protein domains. The enzymatic function of the potato protein could be deduced from the presence of amino acid residues highly conserved in soluble pyrophosphatases and was confirmed by its capacity to complement a thermosensitive pyrophosphatase mutation in E. coli. The potato polypeptide was purified from complemented bacterial cells and its pyrophosphatase activity was shown to be strictly dependent on Mg2+ and strongly inhibited by Ca2+. The subcellular location of the potato pyrophosphatase is unknown. Structure analysis of the N-terminal protein domain failed to recognize typical transit peptides and the calculated molecular mass of the polypeptide (24 kD) is significantly inferior to the values reported for the plastidic (alkaline) or mitochondrial pyrophosphatases in plants (28-42 kD). Two unlinked loci could be mapped by restriction fragment length polymorphism analysis in the potato genome using the full-length cDNA as probe. [less ▲]

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See detailRadiochirurgie et radiothérapie stéréotaxique
Coucke, Philippe ULg; FANKHAUSER

in Médecine et Hygiène (1995), 53(2088), 2002--2009

La radiochirurgie, appelée radiothérapie stéréotaxique lorsqu'il s'agit d'un traitement fractionné, s'effectue en Suisse depuis 1993, soit par accélérateur linéaire modifié, soit par Gamma Knife. Par ... [more ▼]

La radiochirurgie, appelée radiothérapie stéréotaxique lorsqu'il s'agit d'un traitement fractionné, s'effectue en Suisse depuis 1993, soit par accélérateur linéaire modifié, soit par Gamma Knife. Par cette technique on arrive à administrer une dose élevée de radiations à des lésions intracrâniennes circonscrites d'une taille de 3 à 4 cm au maximum, tout en ménageant les tissus normaux avoisinants. Lorsque les lésions sont plus grandes, mal délimitées, ou de forme irrégulière, c'est la radiothérapie conventionnelle et conformationnelle qui offre une meilleure répartition des doses. Les principales lésions considérées pour la radiochirurgie sont les malformations artérioveineuses, les métastases cérébrales solitaires, les méningiomes de la base, les schwannomes vestibulaires et certaines récidives focales de gliomes. [less ▲]

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See detailVaricella-zoster virus latency in the adult rat is a useful model for human latent infection
Sadzot-Delvaux, Catherine ULg; Debrus, Serge; Nikkels, Arjen ULg et al

in Neurology (1995), 45(12, suppl. 8), 18-20

A model of latent infection by varicella-zoster virus (VZV) was obtained in the adult rat. Inoculation of VZV-infected cells in the skin led to infection of the peripheral nervous system. Latency was ... [more ▼]

A model of latent infection by varicella-zoster virus (VZV) was obtained in the adult rat. Inoculation of VZV-infected cells in the skin led to infection of the peripheral nervous system. Latency was characterized by a long-lasting presence of the viral genome, of selected viral gene transcripts, and of at least one viral protein in the dorsal root ganglia. Reactivation has not been obtained in vivo, but has occurred ex vivo after repeated stresses. Many similarities with VZV latency in humans were found, making this model useful for vaccine and antiviral studies. [less ▲]

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See detailSuperovulation in cows with FSH preparation containing different amounts of LH
Smorag, Z.; Beckers, Jean-François ULg; Bychawski, S. et al

in Roczniki Naukowe Zootechniki (1995), 22(2), 103-108

One of the main factors influencing the effectiveness of superovulation is the quality of gonadotropin used.Especially the proportion of FSH to Lh can play an important role.In the experiment ... [more ▼]

One of the main factors influencing the effectiveness of superovulation is the quality of gonadotropin used.Especially the proportion of FSH to Lh can play an important role.In the experiment superovulatory response of cows treated with FSH containing different amounts of LH was evaluated.Observations were carried out on 120 Polish Black-and-White Lowland cows aged from 5 to 8 years.On day 9, 10 and 11 after oestrus, 40 mg of FSH containing 10,20 or 40% of LH was injected in 8 decreasing doses at 12 h intervals.In the control group 3000 IU PMSG per cow was administrated.Forty-eight hours after the initial FSH or PMSG injection, 3 ml PGF 2-alpha analog was injected to donors to induce oestrus.An average of 5.6, 5.3, 3.9 and 1.7 transferable embryos was recovered after treatment of the cows with FSH +20% LH, FSH +40% LH, FSH +10% LH and PSMG, respectively. [less ▲]

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See detailLe traitement oncologique : polémique ou consensus ?
Coucke, Philippe ULg; MARTY

in Médecine et Hygiène (1995), 53(2076), 1371-1377

Les avis en oncologie sont souvent divergents. Ils illustrent un manque de «standard» thérapeutique bien établi. Cette revue a pour but de définir certaines de ces divergences fortement colorées par la ... [more ▼]

Les avis en oncologie sont souvent divergents. Ils illustrent un manque de «standard» thérapeutique bien établi. Cette revue a pour but de définir certaines de ces divergences fortement colorées par la spécialisation du médecin consulté. Ces divergences cesseront d'exister à condition de conduire des essais randomisés. Le praticien généraliste a un rôle prépondérant à jouer dans la motivation des malades afin qu'ils acceptent l'idée de ce genre d'étude. [less ▲]

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See detailCellular and molecular aspects of thymic T-cell education to neurohypophysial peptides
Geenen, Vincent ULg; Martens, Henri ULg; Vandersmissen, Eric et al

in Excerpta Medica (1995), 1098

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See detailHyperfine structure of infrared vanadium lines
Palmeri, P.; Biémont, Emile ULg; Aboussaïd, A. et al

in Journal of Physics : B Atomic Molecular & Optical Physics (1995), 28

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See detailBeyond Borders. West European Migration Policy towards the 21st Century de S. Collinson
Martiniello, Marco ULg

in Ethnic and Racial Studies (1995), 18(2), 421-422

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See detailHysteroscopic myomectomy.
Donnez, Jacques; Polet, Roland; Smets, Mireille et al

in Current Opinion in Obstetrics & Gynecology (1995), 7(4), 311-6

Transhysteroscopic myomectomy has proved to be safe and effective with experienced operators. The use of the continuous flow hysteroscope and preoperative monitoring of intrauterine pressure has ... [more ▼]

Transhysteroscopic myomectomy has proved to be safe and effective with experienced operators. The use of the continuous flow hysteroscope and preoperative monitoring of intrauterine pressure has contributed to the prevention of fluid intravasion accidents. Effectiveness has been demonstrated in a number of recently published long-term studies. [less ▲]

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See detailChimiosensibilité in vivo et in vitro de Plasmodium falciparum à Brazzaville (Congo)
Chandenier, Jacques; Ndounga, Mathieu; Carme, Bernard et al

in Santé : Cahiers d'Etude et de Recherches Francophones (1995), 5(1), 25-29

Various projects were launched in 1993 to monitor the chemosensitivity of Plasmodium falciparum in Congo. Resistance of 34 strains in Brazzaville to chloroquine, quinine and mefloquine and of 35 to ... [more ▼]

Various projects were launched in 1993 to monitor the chemosensitivity of Plasmodium falciparum in Congo. Resistance of 34 strains in Brazzaville to chloroquine, quinine and mefloquine and of 35 to halofantrine was investigated in an in vitro survey using an isotopic micro test. The resistance rates were 61.8, 14.7, 3.0 and 0.0% respectively. Thus, the chemoresistance which first appeared in 1990 is confirmed and is stable in the population. This finding was further confirmed by a parallel in vitro analysis of sensitivity to chloroquine in Brazzaville. A chloroquine monitoring network is now being established throughout the country based on simplified WHO tests of 100 asymptomatic schoolchildren conducted every six months. The first results in 1993, from three Southern regions indicate that parasites are found in 20 to 60% of cases seven days after a standard 3 day treatment with 25 mg/kg, according to the region. The results of in vitro and in vivo tests are very variable. Indeed, the value of such results for these tests for national monitoring is questionable: a more reliable system of identifying true therapeutic failures would be better suited. [less ▲]

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See detailFactors regulating megakaryocyte progenitor commitment to polyploidization.
Paulus, Jean-Michel ULg; Grosdent, J C; Prenant, M et al

in Comptes Rendus de l'Académie des Sciences. Série III. Sciences de la Vie (1995), 318(3), 381-6

Recognizable megakaryocytes are polyploid cells generated by a clonogenic, diploid progenitor, termed CFU-MKC (colony forming unit, megakaryocyte). In order to quantify polyploidization, ploidy histograms ... [more ▼]

Recognizable megakaryocytes are polyploid cells generated by a clonogenic, diploid progenitor, termed CFU-MKC (colony forming unit, megakaryocyte). In order to quantify polyploidization, ploidy histograms of megakaryocytes determined by microphotometric or flow cytometric measurements of megakaryocyte DNA have generally been used. However these techniques provide no information on the rate of commitment of CFU-MKC to polyploidy. Using a technique of clonal analysis determining the distributions of the number of doublings (NbD) undergone by CFU-MKC before committing to polyploidization, the polyploidization probability of CFU-MKC could be derived. This probability was found to be a constant independent from CFU-MKC mitotic history, since NbD distributions are exponential functions characterized by a constant rate of decay per doubling. By studying the effects of growth factors on polyploidization probability, it was also shown that: (1) this parameter is negatively regulated by growth factors contained in poke-weed or WEHI conditioned media, as well as by erythropoietin; (2) commitment to polyploidization does not require prior CFU-MKC division; (3) bipotent erythroid-megakaryocyte progenitors have a lower polyploidization probability than CFU-MKC; (4) determination of polyploidization probability reflects the activity of growth factors with greater accuracy than megakaryocyte colony count. [less ▲]

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See detailThe effect of gonadal development and sex steroids on growth hormone secretion in the male tilapia hybrid (Oreochromis niloticus x O. aureus O;
Melamed, P.; Eliahu, N.; Ofir, M. et al

in Fish Physiology and Biochemistry (1995)

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See detailThe role of the insurance industry in piloting private sector security and prevention policy
Lemaître, André ULg

in European Journal on Criminal Policy and Research (1995), 3.1

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See detailÀ propos des graphies dans les Late Ramesside Letters
Winand, Jean ULg

in Lingua Aegyptia [= LingAeg] (1995), 4

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See detailLes routes de la foi en pays mosan (IVe-XVe siècles). Sources, méthode et problématique
George, Philippe ULg

in Feuillets de la Cathédrale de Liège (1995)

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See detailConfirmation bias as a social skill
Dardenne, Benoît ULg; Leyens, J.

in Personality & Social Psychology Bulletin (1995), 21

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See detailIntérêt de la cyclosporine et du méthotrexate dans le traitement de l'asthme.
weber, T.; Skaventos, I.; Kayembe, J. et al

in Médecine et Hygiène (1995), 53

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See detailNonfibrous mineralogical analysis of bronchoalveolar lavage fluid from blast-furnace workers.
CORHAY, Jean-Louis ULg; Bury, Thierry ULg; Delavignette, Jean-Paul ULg et al

in Archives of Environmental Health (1995), 50(4), 312-9

Steelworkers are exposed to many pollutants, and they are at risk for developing lung cancer. We demonstrated previously that steelworkers may be subject to an occult exposure to amphiboles in the plant ... [more ▼]

Steelworkers are exposed to many pollutants, and they are at risk for developing lung cancer. We demonstrated previously that steelworkers may be subject to an occult exposure to amphiboles in the plant environment. In the current study, we further analyzed bronchoalveolar lavage fluid of steelworkers by measuring intramacrophagic trace-metal content and nonfibrous mineral particles, using the particle-induced x-ray emission method and electron microscopy, respectively. Forty-seven blast-furnace workers and 45 healthy white-collar workers volunteered for this study. Significantly increased levels of iron, titanium, zinc, and bromine were found in the steelworkers, and levels of lead, chromium, arsenic, and strontium tended to increase in the macrophages and bronchoalveolar lavage fluid of the steelworkers. Nonfibrous particles, including illite, kaolinite, talc, chlorite, amorphous silica, quartz, iron (compounds), and titanium hydroxide, were found in both groups, but the particle number per ml bronchoalveolar lavage fluid (particularly iron hydroxides and silicates) was more pronounced in blast-furnace workers. These elements and particles may act synergistically with other occupational carcinogens and cigarette smoke, the result of which may be an increased incidence of lung cancer in the ironsteel industry. [less ▲]

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See detailCoexpression of cytokeratin and vimentin in eutopic endometrium and endometriosis throughout the menstrual cycle: evaluation by a computerized method.
NISOLLE, Michelle ULg; Casanas-Roux, Françoise; Donnez, Jacques

in Fertility and Sterility (1995), 64(1), 69-75

Objectives: To evaluate quantitatively cytokeratin and vimentin staining in glandular and stromal cells of eutopic and ectopic endometrium. DESIGN: The investigation of cytokeratin and vimentin was ... [more ▼]

Objectives: To evaluate quantitatively cytokeratin and vimentin staining in glandular and stromal cells of eutopic and ectopic endometrium. DESIGN: The investigation of cytokeratin and vimentin was carried out using the new computerized technology of image analysis. SETTING: University Hospital, Department of Gynecology. PATIENTS: Biopsies were taken from patients undergoing a laparoscopy for infertility (29 endometrial biopsies and 31 biopsies of peritoneal endometriosis). None of them were treated. RESULTS: Cyclic variations of cytokeratin and vimentin staining were noted in eutopic endometrium. The cytokeratin and vimentin staining pattern consistently was lower in ectopic endometrium than in eutopic endometrium. CONCLUSIONS: Endometriotic epithelial and stromal cells undergo a complex program of differentiation giving them histochemical characteristics similar to those observed in endometrium. Such a concomitant expression of antigenicity indicates their close relationship with their mesodermal müllerian origin. [less ▲]

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See detailSIMULTANEOUS OBSERVATIONS OF THE SATURNIAN AURORA AND POLAR HAZE WITH THE HST/FOC
Gérard, Jean-Claude ULg; DOLS, V.; Grodent, Denis ULg et al

in Geophysical Research Letters (1995), 22(20), 2685-2688

Near simultaneous observations of the Saturnian H-2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the post-COSTAR Hubble ... [more ▼]

Near simultaneous observations of the Saturnian H-2 north ultraviolet aurora and the polar haze were made at 153 nm and 210 nm respectively with the Faint Object Camera on board the post-COSTAR Hubble Space Telescope. The auroral observations cover a complete rotation of the planet and, when co-added, they reveal the presence of an auroral emission near 80 degrees N with a brightness of about 150 kR of total H-2 emission. The maximum vertical optical depth at 210 nm is found to be located similar to 5 degrees equatorward of the auroral emission zone. The haze particles are presumably formed by hydrocarbon aerosols initiated by H-2(+) auroral production. In this case, the 3 x 10(10) W of H-2 emission observed with the FOG, combined with the deduced haze optical depth requires an efficiency of aerosol formation of about 7%. This result indicates that auroral production of hydrocarbon aerosols is a viable source of high-latitude haze. [less ▲]

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See detailPhospholipid-Binding And Lecithin-Cholesterol Acyltransferase Activation Properties Of Apolipoprotein-A-I Mutants
Holvoet, P.; Zhao, Za.; Vanloo, B. et al

in Biochemistry (1995), 34(41), 13334-42

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space ... [more ▼]

Recombinant human apolipoprotein A-I (apo A-I) and three deletion mutants: apo A-I(delta Leu44-Leu126), apo A-I(delta Glu139-Leu170), and apo A-I(delta Ala190-Gln243), purified from the periplasmic space of Escherichia coli, were studied. The rate of turbidity decrease following mixing of apo A-I(delta Ala190-Gln243) with dimyristoylphosphatidylcholine (DMPC) vesicles at 23 degrees C was 10-fold lower than that of the other apo A-I proteins, confirming that the carboxy-terminal region of apo A-I plays a role in rapid lipid binding. The Stokes radii of reconstituted high-density lipoproteins (rHDL), containing dipalmitoylphosphatidylcholine and cholesterol, were larger for the three apo A-I mutants [6.3 nm for apo A-I(delta Leu44-Leu126), 6.1 nm for apo A-I(delta Glu139-Leu170), and 6.5 nm for apo A-I(delta Ala190-Gln243)] than for intact apo A-I (5.0 nm). The mutant rHDL all contained 4 apo A-I molecules per particle as compared to 2 for intact apo A-I. Circular dichroism measurements revealed 8 alpha-helices per apo A-I molecule, 5 per apo A-I(delta Leu44-Leu126), 6 per apo A-I(delta Glu139-Leu170), and 4 per apo A-I(delta Ala190-Gln243) molecule as compared to predicted values of 8, 5, 6, and 6 alpha-helices, respectively. [less ▲]

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See detailA Frequency-Domain Processor for ScanSAR Images
Barbier, Christian ULg; Rosello-Guasch, Josep

in Preparing for the Future (1995), 5(4), 6-7

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See detailLe développement des fonctions du langage en vue d’une meilleure intégration linguistique: le cas des Italiens de Belgique
Lucchini, Silvia ULg

in Cahiers de l'institut de linguistique de Louvain (1995), 21(1-2), 149-156

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See detailActivation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin
D'Angelo, Gisela; Struman, Ingrid ULg; Martial, Joseph ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (1995), 92(14), 6374-8

A number of factors both stimulating and inhibiting angiogenesis have been described. In the current work, we demonstrate that the angiogenic factor vascular endothelial growth factor (VEGF) activates ... [more ▼]

A number of factors both stimulating and inhibiting angiogenesis have been described. In the current work, we demonstrate that the angiogenic factor vascular endothelial growth factor (VEGF) activates mitogen-activated protein kinase (MAPK) as has been previously shown for basic fibroblast growth factor. The antiagiogenic factor 16-kDa N-terminal fragment of human prolactin inhibits activation of MAPK distal to autophosphorylation of the putative VEGF receptor, Flk-1, and phospholipase C-gamma. These data show that activation and inhibition of MAPK may play a central role in the control of angiogenesis. [less ▲]

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See detail"De l'exequatur et des causes de préférence"
Moreau, Pierre ULg

in Actualités du Droit (1995), (2), 395-410

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See detailCell surface binding of TIMP-2 and pro-MMP-2/TIMP-2 complex
Emmert-Buck, M. R.; Emonard, H. P.; Corcoran, M. L. et al

in FEBS Letters (1995), 364(1), 28-32

Tissue inhibitor of metalloproteinases (TIMP-2) is a low molecular weight proteinase inhibitor capable of inhibiting activated matrix metalloproteinases (MMPs). TIMP-2 is found both free and in a 1:1 ... [more ▼]

Tissue inhibitor of metalloproteinases (TIMP-2) is a low molecular weight proteinase inhibitor capable of inhibiting activated matrix metalloproteinases (MMPs). TIMP-2 is found both free and in a 1:1 stoichiometric complex with the pro-enzyme form of MMP-2 (pro-MMP-2/TIMP-2 complex). We have measured the binding of recombinant TIMP-2 to intact HT-1080 and MCF-7 cells. HT-1080 cells in suspension bound 125I-labeled rTIMP-2 with a Kd of 2.5 nM and 30,000 sites/cell. Monolayers of MCF-7 cells were similarly found to bind [125I]rTIMP-2 with a Kd of 1.6 nM and 25,000 sites/cell. Specific binding of MMP-2 alone to HT-1080 cells was not observed; however, pro-MMP-2/TIMP-2 complex was capable of binding to the surface of HT-1080 cells in a TIMP-2-dependent manner. Binding of rTIMP-2 was not competed by the presence of TIMP-1. These results suggest that rTIMP-2 alone binds directly to the cell surface of HT-1080 and MCF-7 cell lines, and TIMP-2 is capable of localizing MMP-2 to the surface of HT-1080 cells via interaction with a specific binding site. [less ▲]

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See detailEstimation of genetic-parameters for growth, feed consumption, and conformation traits for double-muscled Belgian Blue bulls performance-tested in Belgium
Gengler, Nicolas ULg; Seutin, C.; Boonen, F. et al

in Journal of Animal Science (1995), 73(11), 3269-3273

For 1,442 Belgian Blue bulls performance-tested at the Centre de Selection de la Race Blanc-Bleue Belge, nine traits were observed: height at withers at 7 mo, height at withers at 13 mo, weight at 7 mo ... [more ▼]

For 1,442 Belgian Blue bulls performance-tested at the Centre de Selection de la Race Blanc-Bleue Belge, nine traits were observed: height at withers at 7 mo, height at withers at 13 mo, weight at 7 mo, weight at 13 mo, average feed consumption of concentrates, average daily gain, average feed consumption of concentrates per average daily gain, average feed consumption of concentrates per mean metabolic weight, and price per kilogram of live weight. This price is based on muscle conformation and is therefore used as muscle conformation score. Restricted maximum Likelihood with a derivative-free algorithm was used to estimate (co)variance components because there were different models and missing values per trait. Estimates of heritabilities were above .50 except for average feed consumption per average daily gain (.16) and average feed consumption per mean metabolic weight (.33). Estimates of genetic and phenotypic correlations between height at withers and weight traits were positive and moderate to high. Average daily gain showed a negative genetic correlation with weight at 7 mo (- .68) but had positive correlations with height at withers at 13 mo and weight at 13 mo (.22 and .43). Muscle conformation expressed as price per kilogram of live weight was related to low average feed consumption per average daily gain. Average feed consumption showed high correlations with weight at 7 mo and weight at 13 mo. Average feed consumption per average daily gain had a high negative genetic correlation with average daily gain (- .89). [less ▲]

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See detailLes participes présents féminins actifs dans l'Avesta
Swennen, Philippe ULg

in Annali (1995)

In Avestan, much feminine present participles in the active voice are problematic. However, the behaviour of the epenthesis of the feminine suffix is quite perfectly regular.

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See detailDevelopmental disturbance of access to biographical information and people's names: A single-case study
Van der Linden, Martial ULg; Brédart, Serge ULg; Schweich, M.

in Journal of the International Neuropsychological Society (1995), 1(6), 589-595

The paper describes the case of a person (GB) without any clinical evidence of cerebral disease who showed a specific impairment in the retrieval of biographical information, including names, about famous ... [more ▼]

The paper describes the case of a person (GB) without any clinical evidence of cerebral disease who showed a specific impairment in the retrieval of biographical information, including names, about famous people. This deficit appeared while GB scored normally in different long-term memory tasks, and in object naming tasks. Moreover, he showed no impairment in the structural encoding and the recognition of faces. His specific impairment is interpreted both in terms of Bruce and Young's (1986) functional model of person recognition and in terms of the more recent Burton et al. (1990) interactive activation version of the Bruce and Young model. [less ▲]

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See detailA Simple Model for the Fire Resistance of Axially-Loaded Members According to Eurocode 3
Franssen, Jean-Marc ULg; Schleich, Jean-Baptiste; Cajot, Louis-Guy

in Journal of Constructional Steel Research (1995), 35

New buckling curves have been developed for axialy loaded steel members subjected to fire. The model is based on extensive numerical simulations calibrated on several dozens of full scale experimental ... [more ▼]

New buckling curves have been developed for axialy loaded steel members subjected to fire. The model is based on extensive numerical simulations calibrated on several dozens of full scale experimental test results. This model has been subsequently included in Eurocode 3. [less ▲]

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See detailANISOTROPY OF THE MIXED-STATE IN TEXTURED PB-FREE BI-2223 SUPERCONDUCTOR - ELECTRICAL-RESISTIVITY, SEEBECK AND NERNST EFFECTS
PEKALA, M.; Bougrine, Hassan ULg; LADA, T. et al

in Superconductor Science & Technology (1995), 8(9), 726-739

Anisotropy of transport entropy and of Hall angle are reported for the first time through various electrical and thermal transport properties, such as the electric resistivity and the Seebeck and the ... [more ▼]

Anisotropy of transport entropy and of Hall angle are reported for the first time through various electrical and thermal transport properties, such as the electric resistivity and the Seebeck and the Nernst effects (in the presence of a magnetic field ranging between 0 and 4 T), measured for a Pb-free textured Bi-2223 system. The field and temperature influence in the mixed state region is reported only for the H parallel to a and H parallel to c cases and the temperature gradient applied along the b direction. A much stronger influence of magnetic field along the c than the a axis is demonstrated. The relative evolution of the so-called 'excess transport effects' is discussed. We show the laws relating the respective losses to the applied magnetic field. This leads us to the understanding that anisotropic vortex kinetics exist in these systems. We consequently propose two original routes of theoretical investigations to be considered for the calculation of Nernst and TEP effects in a field, in particular to consider a vortex-carrier drag phenomenon. [less ▲]

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See detailGlucose inhibits human placental GH secretion, in vitro
Patel, N.; Alsat, E.; Igout, Ahmed ULg et al

in Journal of Clinical Endocrinology and Metabolism (1995), 80(5), 1743-6

Human placenta specifically expresses the GH-V gene leading to the production of placental Growth Hormone (PGH). During pregnancy, PGH levels increase progressively in maternal blood, but its regulation ... [more ▼]

Human placenta specifically expresses the GH-V gene leading to the production of placental Growth Hormone (PGH). During pregnancy, PGH levels increase progressively in maternal blood, but its regulation remains unknown. In this study the effect of glucose on PGH secretion by human term placenta was tested, in vitro, by means of two different experimental models: organ culture of villous tissue and primary culture of isolated cytotrophoblasts. PGH was assayed in the culture medium by an immunoradiometric assay using a specific PGH monoclonal antibody. The presence of glucose (25 mmol/L) in the culture medium significantly inhibited (p < 0.001) the secretion of PGH by either placental villous explants or by cultured trophoblast cells. This inhibitory effect of glucose on PGH secretion was dose-dependent. More than 50% inhibition being observed with 5.5 mmol/L. In the same conditions, the daily production of hPL and hCG, were unmodified. Furthermore, the glucose-induced inhibition of PGH secretion was more effective when cultured trophoblast cells are differentiated into syncytiotrophoblast. This study demonstrates, for the first time, that among the gestational polypeptide hormones secreted by the human placenta, only PGH secretion is modulated by glucose, suggesting a key metabolic role for this hormone during pregnancy. [less ▲]

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See detailLa grammaire au secours de la datation des textes
Winand, Jean ULg

in Revue d'Egyptologie (1995), 46

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See detailManagement of high turnover osteoporosis with calcitonin
Reginster, Jean-Yves ULg

in Osteoporosis Digest (1995), 3

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See detailMitochondrial oxidative phosphorylation injuries occurring in situ and in vitro.
Willet, K.; Vaz de Macedo, D.; DETRY, Olivier ULg et al

in Transplantation Proceedings (1995), 27

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See detailCombined radiotherapy and radioimmotherapy of human colon carcinoma grafted in nude mice.
Buchegger, F; Rojas, A; Delaloye, A et al

in Cancer Research (1995), 55

The effect of combined radioimmunotherapy (RIT) and fractionated external beam radiotherapy (RT) was assessed in two human colon cancer xenografts, Col 12 and LS174T in nude mice. These tumors were ... [more ▼]

The effect of combined radioimmunotherapy (RIT) and fractionated external beam radiotherapy (RT) was assessed in two human colon cancer xenografts, Col 12 and LS174T in nude mice. These tumors were selected for being resistant to RIT alone, as is usually the case in the clinical situation. Tumor-bearing mice were treated with a combination of five X-ray fractions over 5 days followed by RIT with two doses of 1.5 mCi 131I-labeled anticarcinoembryonic antigen monoclonal antibody F(ab')2. In Col 12 and LS174T, RIT alone achieved a regrowth delay similar to that of fractionated RT with total doses of 28 and 26 Gy, respectively. In both tumor types, an additive therapeutic effect, measured as increased regrowth delay or local control, was observed when combining RT of different dose levels with RIT. Normal tissue responses were assessed by monitoring acute peak skin reactions and blood cell count. Bone marrow depression for the combination treatment was similar to that of RIT alone; relative to skin, at equitoxic levels, no mice bearing Col 12 tumors were locally controlled with a 32 Gy RT dose alone, while this RT combined with RIT gave a local control of 100%. These studies show a therapeutic benefit when external beam RT is combined with RIT. [less ▲]

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See detailTRANSPORT STUDY OF BA-DEFICIENT THIN-FILM Y123 SUPERCONDUCTORS ENRICHED WITH NA
PEKALA, M.; Bougrine, Hassan ULg; AZOULAY, J. et al

in Superconductor Science & Technology (1995), 8(8), 660-666

Nominal Y0.3Ba0.6Na0.1CuO3-delta thin films were prepared with small grains having an orientation of the c axis perpendicular to the MgO substrate. The electrical resistivity and the thermoelectric power ... [more ▼]

Nominal Y0.3Ba0.6Na0.1CuO3-delta thin films were prepared with small grains having an orientation of the c axis perpendicular to the MgO substrate. The electrical resistivity and the thermoelectric power in the absence and in the presence of a magnetic field are reported. The magnetic field dependence of the irreversibility line is discussed. The role of the field for disentangling intragrain and intergrain effects in both coefficients is emphasized. [less ▲]

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See detailELECTRICAL AND THERMOMAGNETIC EFFECTS IN BI1.7PB0.3SR2CA2CU3O10 SUPERCONDUCTING CERAMICS
Pekala, M.; Bougrine, Hassan ULg; Ausloos, Marcel ULg

in Journal of Physics : Condensed Matter (1995), 7(28), 5607-5621

We report the electrical resistivity and thermoelectric power of polycrystalline Pb-doped Pi 2:2:2:3 superconductors. In particular the mixed-state properties are investigated by measuring the ... [more ▼]

We report the electrical resistivity and thermoelectric power of polycrystalline Pb-doped Pi 2:2:2:3 superconductors. In particular the mixed-state properties are investigated by measuring the longitudinal and transverse (Nernst) thermoelectric power. For the first time we show the presence of hysteresis in a high magnetic field for the Nernst effect. We discuss the variation with magnetic field in the properties with respect to the zero-field case and show the power-law behaviour with exponents depending on the transport quantity. We extract 'derived properties' such as the effective mass, the transport entropy, the Ginzburg-Landau parameter, the thermal Hall angle and the activation energy and compare them with previous data on related systems. [less ▲]

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See detailMorphological Changes of Thymus in Retrovirus-Induced Murine Acquired Immunodeficiency Syndrome (Maids)
de Leval, Laurence ULg; Deprez, Manuel ULg; Colombi, S. et al

in Pathology - Research & Practice (1995), 191(6), 506-12

The possible contribution of the thymus in the setting of acquired immunodeficiencies is still questioned. Here we report some new findings regarding a potential involvement of the thymus in mice infected ... [more ▼]

The possible contribution of the thymus in the setting of acquired immunodeficiencies is still questioned. Here we report some new findings regarding a potential involvement of the thymus in mice infected with RadLV-Rs, a viral mixture inducing murine acquired immunodeficiency syndrome (MAIDS). Thymi were sequentially removed, weighted and morphologically analyzed at different time intervals post-infection. Infection with RadLV-Rs led to a decrease in thymus weight mostly apparent from the fourth week. The first changes were seen at the third week as perivascular clusters of B-cells at the cortico-medullary junction. The ensuing process of atrophy mainly involved the cortex, while a mixed population of large T- and B-cells filled the medulla. These observations are discussed with regard to the pathological changes occurring in other lymphoid and non-lymphoid organs, in the context of the lymphoproliferation and immunodeficiency characterizing the disease, and by comparison with other models of retrovirus-induced immunodeficiencies. [less ▲]

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See detailINVESTIGATION OF THE ELECTRICAL-RESISTIVITY BEHAVIOR BETWEEN THE KOSTERLITZ-THOULESS TEMPERATURE AND THE GINZBURG-LANDAU TEMPERATURE IN SPRAY-DRIED BULK BI2SR2CACU2O8+D - THE ROLE OF 2-DIMENSIONAL FLUCTUATIONS AND DEFECTS
Ausloos, Marcel ULg; Bougrine, Hassan ULg; DUVIGNEAUD, P. H. et al

in Physica C (1995), 251(3-4), 337-347

The resistive transition R(T) between the Kosterlitz-Thouless temperature and the Ginzburg-Landau temperature was studied in spray-dried bulk Bi2Sr2CaCu2O8+d superconductors for a magnetic-field range ... [more ▼]

The resistive transition R(T) between the Kosterlitz-Thouless temperature and the Ginzburg-Landau temperature was studied in spray-dried bulk Bi2Sr2CaCu2O8+d superconductors for a magnetic-field range between 0 and 0.3 T. The samples were prepared by the spray-drying technique with Bi2+xSr2-x-yCa2+yCu2O8+d for x = y = 0.05 or 0.1 as a starting composition here. The data analysis was performed assuming various resistive laws previously proposed. When numerically analyzed in terms of a two-dimensional Kosterlitz-Thouless theory the results lead to remarkable quantitative agreement. This implies that the R(T) behavior can be described within a picture of a highly two-dimensional behavior of macroscopic fluctuations of vortex-antivortex depairing type. The role of defects or inhomogeneities in the resistive behavior is outlined. [less ▲]

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See detailSecondary structure of monoamine oxidase by FTIR spectroscopy.
Wouters, J.; Ramsay, R.; Goormaghtigh, E. et al

in Biochemical and Biophysical Research Communications (1995), 208(2), 773-8

The secondary structure of human monoamine oxidase A and bovine monoamine oxidase B has been investigated by Fourier Transform Attenuated Total Reflection Spectroscopy (FTIR ATR). The experimental results ... [more ▼]

The secondary structure of human monoamine oxidase A and bovine monoamine oxidase B has been investigated by Fourier Transform Attenuated Total Reflection Spectroscopy (FTIR ATR). The experimental results are compared for both isoenzymes and the data are incorporated in a statistical attribution of secondary structure of the enzyme describing the distinct folding and molecular specificity of the two types of monoamine oxidase. [less ▲]

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See detailLes troubles obsessionnels compulsifs
Triffaux, Jean-Marc ULg

in stratégie thérapeutique (1995)

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See detailEndogenous reproductive hormones and nocturnal rhythms in partner preference and sexual behavior of ATD-treated male rats.
Bakker, Julie ULg; van Ophemert, J.; Timmerman, M. A. et al

in Neuroendocrinology (1995), 62(4), 396-405

Male rats received subcutaneously silastic capsules, containing the aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD), shortly after birth. Control males were given silastic capsules containing ... [more ▼]

Male rats received subcutaneously silastic capsules, containing the aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD), shortly after birth. Control males were given silastic capsules containing cholesterol. The capsules were removed at the age of 21 days. In adulthood, blood serum was collected early and late in the dark phase of the light/dark cycle (experiment I). Testosterone and luteinizing hormone and follicle stimulating hormone (FSH) fluctuated nocturnally, both in ATD and control males, with highest levels late in the dark phase. FSH levels were significantly higher in ATD males. Nocturnal levels of inhibin, a selective suppressor of pituitary FSH secretion, also fluctuated in both ATD and control males, with lowest levels late in the dark phase. In experiment II, ATD and control males were tested for partner preference behavior in a three-compartment box (choice: sexually active male vs. estrous female) early and late in the dark phase. When gonadally intact, ATD males, but not controls, showed a clear nocturnal rhythmicity in partner preference behavior and sexual behavior. Early in the dark phase, such ATD males preferred the vicinity of and interaction with a sexually active male. Late in the dark phase, this preference for the active male shifted to a preference for the estrous female. Control males preferred the estrous female. After castration and subsequent treatment with testosterone via silastic capsules, which ensured constant blood serum levels, ATD males continued to show their nocturnal rhythms in partner preference behavior and in sexual behavior. Thus, the underlying mechanism of the nocturnal rhythmicity phenomenon is an organizational effect of neonatal ATD treatment rather than an activational effect of fluctuating serum hormone levels. [less ▲]

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See detailEffect of prolonged exercise on neutrophil myeloperoxidase secretion
Bury, Thierry ULg; PIRNAY, Freddy ULg

in International Journal of Sports Medicine (1995)

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See detailComparison of six serum ferritin immunoassays and isoferritin spectrotypes in malignancies
Vernet, M.; Renversez, J. C.; Lasne, Y. et al

in Annales de Biologie Clinique (1995), 53

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See detailReaction Window in the single-electron capture by Ammonia Dications.
Leyh, Bernard ULg; Hoxha, Antuan

in Chemical Physics (1995), 192

Single-electron capture (SEC) by (NH3)2+ with rare gases (He, Ne, Ar, Kr, Xe) and benzene, (NH3)2++G->NH3++G+, has been investigated using a forward geometry double-focussing mass spectrometer. The SEC ... [more ▼]

Single-electron capture (SEC) by (NH3)2+ with rare gases (He, Ne, Ar, Kr, Xe) and benzene, (NH3)2++G->NH3++G+, has been investigated using a forward geometry double-focussing mass spectrometer. The SEC cross-section goes through a maximum within a reaction window centered at an exothermicity of approximately 4.5 eV. This corresponds to a target-projectile distance for the charge transfer of about 3.2 Angstöm. The average internal energy of NH3+-ions resulting from SEC has been obtained both via translational energy gain measurements and via an analysis of the daughter ion spectra. The agreement between both methods is satisfactory and shows that the lower the ionisation energy of the target, the more probable the excitation of NH3+ to the A2E state. With benzene (ionization energy=9.25 eV) as the target gas, however, the excess energy is converted partly to internal energy of C6H6+, leading most probably to the D2B2u, E2B1u and F2A1g states of C6H6+. A model based on the Landau-Zener non-adiabatic formalism, including one entrance channel (NH32++G) and two exit channels (NH3+ X2A"2+G+ and NH3+ A2E+G+) accounts qualitatively for the observed results in the case of exothermic single-electron capture. This model is not appropriate for slightly exothermic and endothermic charge transfer, i.e., in the present case, for the Ne and He target gases. [less ▲]

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See detailNF-kappaB transcription factor activation by hydrogen peroxide can be decreased by 2,3-dihydroxybenzoic acid and its ethylester derivative
Sappey, Christine; Boelaert, J. R.; Legrand-Poels, Sylvie ULg et al

in Archives of Biochemistry & Biophysics (1995)

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