References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailEnzymes from psychrophilic organisms
Feller, Georges ULg; Narinx, E.; Arpigny, J. L. et al

in FEMS Microbiology Reviews (1996), 18(2-3), 189-202

Psychrophilic organisms such as micro-organisms and other ectothermic species living in polar, deep- sea or any constantly low temperature environments, produce enzymes adapted to function at low ... [more ▼]

Psychrophilic organisms such as micro-organisms and other ectothermic species living in polar, deep- sea or any constantly low temperature environments, produce enzymes adapted to function at low temperature. These enzymes are characterized by a high catalytic efficiency at low and moderate temperatures but are rather thermolabile. Due to their high specific activity and their rapid inactivation at temperatures as low as 30 degrees C, they offer, along with the producing micro-organisms, a great potential in biotechnology. The molecular basis of the adaptation of cold cu-amylase, subtilisin, triose phosphate isomerase from Antarctic bacteria and of trypsin from fish living in North Atlantic and in Antarctic sea waters have been studied. The comparison of the 3D structures obtained either by protein modelling or by X-ray crystallography (North Atlantic trypsin) with those of their mesophilic counterparts indicates that the molecular changes tend to increase the flexibility of the structure by a weakening of the intramolecular interactions and by an increase of the interactions with the solvent. For each enzyme, the most appropriate strategy enabling it to accommodate the substrate at a low energy cost is selected. There is a price to pay in terms of thermosensibility because the selective pressure is essentially oriented towards the harmonization of the specific activity with ambient thermal conditions. However, as demonstrated by site-directed mutagenesis experiments carried out on the Antarctic subtilisin, the possibility remains to stabilize the structure of these enzymes without affecting their high catalytic efficiency. [less ▲]

Detailed reference viewed: 43 (6 ULg)
Peer Reviewed
See detailCompte-rendu de Pascal Engel, Philosophie et psychologie
Leclercq, Bruno ULg

in Revue Philosophique de Louvain (1996), 94

Detailed reference viewed: 76 (2 ULg)
Full Text
Peer Reviewed
See detailDemande d'indemnisation des dommages dus aux plans : éléments de recevabilité et de fondement
Delnoy, Michel ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1996)

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailExperimental model for the study by chemiluminescence of the activation of isolated equine leucocytes.
Benbarek, H.; Deby, Ginette ULg; Deby, C. et al

in Research in Veterinary Science (1996), 61(1), 59-64

The activation of human polymorphonuclear leucocytes (the respiratory burst) can be studied by measuring their chemiluminescent response. This technique was adapted to equine leucocytes to investigate the ... [more ▼]

The activation of human polymorphonuclear leucocytes (the respiratory burst) can be studied by measuring their chemiluminescent response. This technique was adapted to equine leucocytes to investigate the effects of cell number, activator concentration, enhancers of chemiluminescence, pH, temperature and inhibitors. Leucocytes were isolated from citrated blood from healthy horses and chemiluminescence was measured with a Bio-Orbit luminometer sensitive to 900 nm light. The optimal cell density for the maximal chemiluminescent response ranged from 10(6) to 10(7) leucocytes 600 microliters-1. Chemiluminescence increased as a function of temperature, and the concentrations of luminol, lucigenin and phorbol myristate acetate (PMA), and was pH related (optimal pH value = 8.0 for lucigenin and 8.5 for luminol). The inhibition of chemiluminescence by 5 x 10(-5) M azide was 88 per cent for luminol and 37 per cent for lucigenin. Superoxide dismutase (100 IU) totally inhibited the chemiluminescence response. Approximately 30 per cent variability in chemiluminescence was observed under the same assay conditions, depending on the origin of the leucocytes. Based on these results, the conditions selected for the measurement of equine leucocyte chemiluminescence were: 10(6) to 10(7) leucocytes 600 microliters-1, 1 x 10(-6)M PMA, 1 mM luminol or 0.4 mM lucigenin, physiological pH (7.4) and physiological temperature (37.8 degrees C). These conditions were similar to those used for measuring the chemiluminescent response of human leucocytes. [less ▲]

Detailed reference viewed: 32 (1 ULg)
Full Text
Peer Reviewed
See detailFreud, l'individu et le groupe : Hier et aujourd'hui
Carels, N.; Gauthier, Jean-Marie ULg

in Revue Belge de Psychanalyse (1996), 29

Detailed reference viewed: 25 (2 ULg)
Full Text
See detailLe frêne, un bois noble et précieux
Claessens, Hugues ULg

in Forêt Wallonne (1996), 28

Avec le bouleau, l'aulne glutineux, les tilleuls, les érables, le merisier et d'autres feuillus relativement marginaux dans le marché du bois, le frêne fait partie des espèces secondaires de la forêt ... [more ▼]

Avec le bouleau, l'aulne glutineux, les tilleuls, les érables, le merisier et d'autres feuillus relativement marginaux dans le marché du bois, le frêne fait partie des espèces secondaires de la forêt wallonne, qui, ensemble ne représentent que 7% du volume sur pied, alors qu'à eux seuls, le hêtre, les chênes et l'épicéa en totalisent 85% (données IFW). Certaines, comme le frêne, sont qualifiées de "nobles" ou encore de "précieuses" en raison de leur valeur marchande (frêne, érable et merisier). Une des causes de ce phénomène est le choix délibéré des propriétaires forestiers, qui, pour des raisons que nous connaissons, à la fois historiques et liées aux marchés du bois passé et actuel, ont préféré le hêtre, le chêne et l'épicéa, souvent sous forme de monoculture, réduisant ainsi l'espace qui revenait naturellement aux espèces secondaires, naturellement disséminées dans nos forêts. [less ▲]

Detailed reference viewed: 25 (6 ULg)
Peer Reviewed
See detailNeurophysins in central diabetes insipidus
Legros, Jean-Jacques ULg; Geenen, Vincent ULg

in Hormone Research (1996), 45

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailCardiovascular involvement during HIV infection.
Valdes, E. F.; Fernandez, R. E.; Villanueva, H. R. et al

in European Heart Journal (1996), 17(10), 1605

Detailed reference viewed: 9 (8 ULg)
Full Text
Peer Reviewed
See detailOpportunities for using two low-cost methods for treatment of metal bearing aqueous streams
Gaydardzhiev, Stoyan ULg; Hadjihristova, M.; Tichy, R.

in Minerals Engineering (1996), 9

The feasibility of two non-traditional approaches - reedbeds as a natural wetland and adsorption on lignite and its maceral fractions - for their application in metal bearing effluent treatment is ... [more ▼]

The feasibility of two non-traditional approaches - reedbeds as a natural wetland and adsorption on lignite and its maceral fractions - for their application in metal bearing effluent treatment is discussed. The main mechanisms of metals uptake are otulined. The preliminary results from a pilot scale wetland operation for metallurgical effluents purification are analysed. For the second approach - the different maceral fractions derived from coal refining have shown different metal uptake apptitude. Zeta potential studies and adsorption isotherms have explained these findings. [less ▲]

Detailed reference viewed: 20 (6 ULg)
Peer Reviewed
See detailA preliminary study of parasites and diseases of perch in an intensive culture system
Grignard, Jean-Claude; Mélard, Charles ULg; Kestemont, Patrick

in Journal of Applied Ichthyology (1996), 12

Detailed reference viewed: 8 (0 ULg)
Peer Reviewed
See detailCompte rendu de Le clerc séculier au Moyen Age, Paris, 1993
George, Philippe ULg

in Cahiers de Clio (1996)

Detailed reference viewed: 6 (0 ULg)
Full Text
Peer Reviewed
See detailInterleukine 1 et métabolisme osseux
Reginster, Jean-Yves ULg; Zheng, SX

in Revue du Praticien (La) (1996), 46

Detailed reference viewed: 9 (2 ULg)
Peer Reviewed
See detailRegulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.
De Smedt, T.; Pajak, B.; Muraille, E. et al

in Journal of Experimental Medicine (1996), 184(4), 1413-24

Dendritic cells (DC) are described as "nature's adjuvant," since they have the capacity to sensitize T cells in vivo upon first encounter with the antigen. The potent accessory properties of DC appear to ... [more ▼]

Dendritic cells (DC) are described as "nature's adjuvant," since they have the capacity to sensitize T cells in vivo upon first encounter with the antigen. The potent accessory properties of DC appear to develop sequentially. In particular, the ability to process antigens and to sensitize native T cells develops in sequence, a process termed "maturation" that is well described in vitro. Here, we obtain evidence for maturation in vivo in response to the bacterial product lipopolysaccharide (LPS). Before LPS treatment, many DC are found at the margin between the red and white pulp. These cells lack the M342 and DEC-205 markers, but process soluble proteins effectively. 6 h after LPS, DC with the M342 and DEC-205 markers are found in increased numbers in the T cell areas. These cells have a reduced capacity to process proteins, but show increases in the B7 costimulator and T cell stimulatory capacity. 48 h after LPS, the number of DC in the spleen is reduced markedly. We interpret these findings to mean that LPS can cause DC in the marginal zone to mature and to migrate into and then out of the T cell areas. [less ▲]

Detailed reference viewed: 34 (0 ULg)
Peer Reviewed
See detailFaded Dreams - M. Carnoy
Martiniello, Marco ULg

in New Community (1996), 22(3), 547-548

Detailed reference viewed: 10 (1 ULg)
Peer Reviewed
See detailLower Devonian Palynomorphs from the Talacasto Formation, Cerro del Fuerte Section, San Juan Precordillera, Argentina
Le Hérissé, A; Rubinstein, CR; Steemans, Philippe ULg

in Acta Universitatis Carolinae. Geologica (1996), 40(3-4), 497-515

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailInhibition of Paf-Induced Platelet Aggregation by Web 2086 'in-Vitro', an Antagonist to the Receptor for Platelet-Activating Factor, in Bovine
Bastos da Silva, Miriam; Herion, Francine ULg; Raskinet, Renée ULg et al

in Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine (1996), 43(7), 399-413

The sensitivity of bovine platelet aggregation in response to PAF stimulation and the ability of WEB 2086 (a thieno-triazolodiazepine) to inhibit response to PAF-induced platelet aggregation were ... [more ▼]

The sensitivity of bovine platelet aggregation in response to PAF stimulation and the ability of WEB 2086 (a thieno-triazolodiazepine) to inhibit response to PAF-induced platelet aggregation were investigated in the blood from five healthy male Belgian Blue calves. The recorded response to PAF showed a plateau which was dependent on the PAF concentration. Platelet aggregation induced by PAF consists of two mechanisms: reversible and irreversible aggregations which are accompanied by the release of platelet granule contents. Reversible aggregation occurred above (2 . 10(-9) mol/l) PAF, and irreversible aggregation occurred above (2 . 10(-7) mol/l) PAF. Addition of WEB 2086 to bovine platelets in vitro induced a rightward shift in the dose-response curve to PAF. WEB 2086 inhibited PAF-induced aggregation in a competitive reversible manner (pA2 = 7.61). The results of our study show that PAF induces platelet aggregation in platelet-rich plasma (PRP) and that addition of WEB 2086 to bovine platelets in vitro inhibits PAF-induced Platelet Aggregation. [less ▲]

Detailed reference viewed: 70 (3 ULg)
Full Text
Peer Reviewed
See detailAvoided resonance overlapping beyond the energy independent formalism. II. Electronic predissociation
Brems, Vincent; Desouter, Michèle ULg; Liévin, Jacques

in Journal of Chemical Physics (1996), 104

Detailed reference viewed: 2 (0 ULg)
See detailRace and Class in the South since 1890 - M. Stokes et R. Halpern (eds.)
Martiniello, Marco ULg

in Migration World Magazine (1996), 24(5), 46

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailIncidence of Inflammatory Bowel Disease in the Province of Liege (Belgium). La Societe De Gastroenterologie Liegeoise
Latour, Pascale ULg; Belaiche, Jacques ULg; Louis, Edouard ULg et al

in Acta Gastro-Enterologica Belgica (1996), 59(1, Jan-Mar), 3-6

Up to now, as there is no national registry of patients with inflammatory bowel disease (IBD) in Belgium, the study of IBD epidemiology in our country is only possible through institutional or regional ... [more ▼]

Up to now, as there is no national registry of patients with inflammatory bowel disease (IBD) in Belgium, the study of IBD epidemiology in our country is only possible through institutional or regional series. Therefore we conducted a prospective epidemiologic study of IBD in the Province of Liege (1 million inhabitants). METHODS: 29 (out of 47) private and public gastroenterologists completed a standard questionnaire for each patient consulting for the first time with clinical symptoms compatible with IBD between 1/06/1993 and 31/05/1994. RESULTS: During that period 104 cases of IBD were recorded: 56 (54%) Crohn's disease (CD), 36 (35%) ulcerative colitis (UC) including 7 proctitis (19% of UC) and 12 (11%) unclassified colitis. The annual incidence was 5.5 per 100.000 for CD and 3.5 for UC. The sex ratio F/M was 1.7 for CD and 0.7 for UC. The median age at the time of diagnosis was 33.5 yrs for CD and 40 yrs for UC. The highest age specific incidence rate for CD and UC was between 20 and 29 yrs : 13.6 and 6.1, respectively. CONCLUSIONS: This first Belgian prospective study has shown an incidence rate for CD comparable with that seen in north European studies but lower than that seen for UC. These results were similar to those observed in the northern part of France. Belgium appears to be a privileged country to undertake a national register and to study epidemiological aspects of IBD. [less ▲]

Detailed reference viewed: 51 (4 ULg)
Full Text
Peer Reviewed
See detailA new HPLC method for the assay of alkaloids in Strychnos nux-vomica and Strychnos ignatii
Gadi Biala, Rose; Tits, Monique ULg; Wauters, Jean-Noël ULg et al

in Fitoterapia (1996), 67(2), 163-165

A reversed-phase high performance liquid chromatographic procedure was developed for the qualitative and quantitative analysis of the alkaloids in S. nux-vomica and S. ignatii.

Detailed reference viewed: 61 (8 ULg)
Full Text
Peer Reviewed
See detail9-Methoxygeissoschizol, an alkaloid from bark of strychnos guianensis
Mavar-Manga, Hélène; Quetin-Leclercq, Joëlle; Llabres, Gabriel ULg et al

in Phytochemistry (1996), 43(5), 1125-1127

The isolation and structure determination of 9-methoxygeissoschizol from the stem bark of Strychnos guianensis is described. Elucidation of its structure is mainly based on NMR studies.

Detailed reference viewed: 21 (2 ULg)
Peer Reviewed
See detailTaqi Growth Hormone Gene Polymorphism And Milk Production Traits In Holstein-Friesian Cattle
Falaki, M.; Sneyers, M.; Prandi, A. et al

in Animal Science (1996), 63

Detailed reference viewed: 25 (2 ULg)
Full Text
Peer Reviewed
See detailThe Erythrocyte/Brain Glucose Transporter (Glut1) May Adopt A Two-Channel Transmembrane Alpha/Beta Structure.
Ducarme, P.; Rahman, M.; Lins, Laurence ULg et al

in Journal of Molecular Modeling (1996), 2(2), 27-45

There are two models of topology for the membrane domains of the erythrocyte/brain facilitative glucose transporter, GLUT1. The first is composed of 12 membrane-spanning a-helices, the second of 16 ... [more ▼]

There are two models of topology for the membrane domains of the erythrocyte/brain facilitative glucose transporter, GLUT1. The first is composed of 12 membrane-spanning a-helices, the second of 16 membrane-spanning b-strands. We have used Jähnig’s and Eisenberg’s methods to identify possible transmembrane segments (10 spanning a-helices and 4 b-strands). The topology proposed is more consistent with available experimental data from FTIR, CD and mapping experiment than the previous models . We suggest that GLUT1 might form two channels, one of which is responsible for glucose transport. This agrees with the theoretical and experimental arguments. Finally, an analysis of the mutation periodicity and of the mean hydrophobicity for the GLUT family is provided in order to evaluate the packing of the protein in the membrane. Keywords: [less ▲]

Detailed reference viewed: 12 (0 ULg)
See detailLe Calendrier et son Histoire
Biémont, Emile ULg

in Bulletin de la Classe des Sciences. Académie Royale de Belgique (1996), 6e série(VII), 15-71

Detailed reference viewed: 6 (3 ULg)
Peer Reviewed
See detailCalculations of inner shell transitions in Ca+
Hansen, J E; Quinet, Pascal ULg

in Journal of Electron Spectroscopy & Related Phenomena (1996), 79

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailFormes pharmaceutiques à libération prolongée en médecine vétérinaire : systèmes à rétention dans le réticulo-rumen = Sustained-released veterinary dosage forms : retention devices in the reticulorumen
Evrard, Brigitte ULg; Delattre, Luc ULg

in STP Pharma Pratiques (1996), 6(6), 479-486

L'industrialisation des productions animales a mis en évidence la nécessité d'éviter des administrations réitérées chez des animaux dont la manipulation est difficile, et de développer des formes à ... [more ▼]

L'industrialisation des productions animales a mis en évidence la nécessité d'éviter des administrations réitérées chez des animaux dont la manipulation est difficile, et de développer des formes à libération contrôlée ou du moins fortement prolongée. L'anatomie particulière du tube digestive des ruminants offre en outre des possibilités inédites pour le développement de tels systèmes thérapeutiques, notamment grâce à la rétention dans le réticulo-rumen. De telles formes ont essentiellement été développées pour l'administration de médicaments antiparasitaires et antibactériens, de suppléments nutritionnels et de promoteurs croissance. Cette revue décrit les applications potentielles de la technologie des formes à libération contrôlée et prolongée en médecine vétérinaire et les différents dispositifs à rétention dans le réticulo-rumen décrits dans la littérature, brevetés ou commercialisés. More intensive methods ofanimal husbandry have revealed the necessity of avoiding repeated administration ofmedication to animals which are difficult to handle and of developing controlled and sustained release dosage forms. The physiological characteristics of the digestive tract of ruminants provide unique opportunity for controlled release technology, especially due to the animal's reticulo-rumen retention ability. The majorareas of application of these controlled and sustained release dosage forms include the delivery of antibiotic and antiparasitic agents, trace nutrients and growth promoting agents. This review describes the potential applications of controlled and sustained release technology in veterinary medicine and the various reticulo-rumen retention devices which are patented, marketed or described in the literature. [less ▲]

Detailed reference viewed: 96 (2 ULg)
Peer Reviewed
See detailAu fur et à mesure qu'elles se construisent, les trajectoires professionnelles divergent entre les sexes : l'exemple belge
Gavray, Claire ULg

in Formation Emploi : Revue Française de Sciences Sociales (1996), 93

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailAstroglia-released factor with negative allosteric modulatory properties at the GABA A receptor.
Rigo, Jean-Michel; Belachew, Shibeshih ULg; Coucke, Paul et al

in Biochemical Pharmacology (1996), 52(3), 465-473

We have previously shown, using whole-cell patch-clamp techniques, that astrocytes release a negative allosteric modulator of the gamma-aminobutyric acid type A receptor (GABAA receptor) with beta ... [more ▼]

We have previously shown, using whole-cell patch-clamp techniques, that astrocytes release a negative allosteric modulator of the gamma-aminobutyric acid type A receptor (GABAA receptor) with beta-carboline-like properties, thus, likely to act at the benzodiazepine site. Here, using patch-clamp and binding techniques, we confirm that the low-molecular-weight fraction of astroglia-conditioned medium (ACM lmf) contains a factor(s) that negatively modulates GABAA-receptor function. This factor, like beta-carbolines, enhances the specific binding of [35S]t-butyl bicyclophosphorothionate (TBPS) to adult rat cortical membranes in the presence of GABA. However, it fails to interact with various ligands of the benzodiazepine (BZD) site of the GABAA receptor ([3H]flunitrazepam, [3H]Ro 15-1788 and [3H]Ro 15-4513). The question of the actual binding site of the astroglia-derived factor on the GABAA receptor, thus, remains open and can be addressed only after the purification of the active molecule(s) of ACM Imf has been completed, and a labeled form of the endogenous ligand becomes available. Taken together, however, the data suggest that type 1 astrocytes are able to modulate the effects of the main inhibitory neurotransmission in the central nervous system. [less ▲]

Detailed reference viewed: 21 (1 ULg)
Peer Reviewed
See detailIn vitro activity of amoxycillin/clavulanate and ticarcillin/clavulanate compared with that of other antibiotics against anaerobic bacteria: comparison with the results of the 1987 survey
Pierard, denis; De Meyer A; Rosseel, P. et al

in Acta Clinica Belgica (1996), 51(2), 70-9

The activity of amoxycillin/clavulanate (Augmentin) and ticarcillin/ clavulanate (Timentin) was tested against 351 strict anaerobic clinical isolates collected from September 1993 to April 1994 in eight ... [more ▼]

The activity of amoxycillin/clavulanate (Augmentin) and ticarcillin/ clavulanate (Timentin) was tested against 351 strict anaerobic clinical isolates collected from September 1993 to April 1994 in eight Belgian university hospitals and compared with that of 8 other antibiotics using the NCCLS reference agar dilution procedure. Production of beta-lactamase was detected by the nitrocefin test in 48% of the isolates. At NCCLS-recommended breakpoints, more than 90% of isolates were susceptible to amoxycillin/clavulanate, ticarcillin/clavulanate, piperacillin/tazobactam, imipenem, chloramphenicol and metronidazole but only 77%, 72% and 48% to cefoxitin, clindamycin and penicillin, respectively. In comparison with the results of a similar survey conducted in 1987 no major changes in susceptibility were observed except for the susceptibility to clindamycin that declined from 83% to 72% overall, and from 83% to 66% in the B. fragilis group. Furthermore one isolate of Clostridium clostridioforme was found produce beta-lactamase and few B. fragilis group isolates showed reduced susceptibility to metronidazole. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Peer Reviewed
See detailA Simple Model for the Fire Resistance of Axially Loaded Members - Comparison with experimental results
Franssen, Jean-Marc ULg; schleich, Jean-Baptiste; Cajot, Louis-Guy et al

in Journal of Constructional Steel Research (1996), 37

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailComparaison des effets de différents types de traitement phytosanitaires des semences de cotonnier au Burundi et en Grèce
Carême, C.; Mergeai, Guy ULg; Ydraiou, Francesca et al

in Tropicultura (1996), 14

Les effets de plusieurs matières actives insecticides et de différentes techniques de traitement des semences du cotonnier ont été étudiés lors de 7 essais réalisés au Burundi et en Grèce en 1993 et 1994 ... [more ▼]

Les effets de plusieurs matières actives insecticides et de différentes techniques de traitement des semences du cotonnier ont été étudiés lors de 7 essais réalisés au Burundi et en Grèce en 1993 et 1994. Les essais menés au Burundi mettent en évidence l'efficacité très hautement significative sur Aphis gossypii Glover de l'imidaclopride à la dose de 3g m.a./kg, associé au chlorothalonil à 0,8 g/kg semences, utilisé en enrobage des semences délintées. L'absence de pression parasitaire n'a pas permis de départager les traitements testés en Grèce en ce qui concerne leur efficacité pour lutter contre les ravageurs qui attaquent le cotonnier au début de son cycle. Les observations écophysiologiques réalisées au cours de ces expérimentations mettent en évidence une amélioration significative de la précocité de la maturation des capsules chez les plantes issues de graines enrobées portant une dose moyenne de 2,2 g d'imidaclopride et 2,4 g de TMTO par kg de semences. Le gain de précocité est en moyenne de 10 jours par rapport au traitement témoin. [less ▲]

Detailed reference viewed: 37 (5 ULg)
Full Text
Peer Reviewed
See detailVaricella-zoster virus : a cause of waxing and waning vasculitis. The New England Journal of Medicine case 5-1995 revisited
Gilden, D. H.; Kleinschmidt-DeMasters, B. K.; Wellish, M. et al

in Neurology (1996), 47(6), 1441-1446

A 73-year-old man developed an ill-defined fatal vasculitis involving the central nervous system. The case report was published as a clinicopathologic exercise in February 1995 in The New England Journal ... [more ▼]

A 73-year-old man developed an ill-defined fatal vasculitis involving the central nervous system. The case report was published as a clinicopathologic exercise in February 1995 in The New England Journal of Medicine.(1) We restudied the pathologic material and found both varicella tester virus (VZV) DNA and VZV-specific antigen, but not herpes simplex virus (HSV) or cytomegalovirus (CMV) DNA or HSV- or CMV-specific antigen, in three of the five cerebral arteries examined. The inflammatory response, disruption of the internal elastic lamina, and detection of viral antigen were patchy from one artery to another, as well as within a given artery. A search for VZV should be conducted in cases of vasculitis when both the central and peripheral nervous systems are involved, when focal narrowing is present in large arteries, when brain imaging reveals infarction in gray and white matter, both deep and superficial, and when white matter is disproportionally involved. Zosteriform rash is not required for diagnosis. [less ▲]

Detailed reference viewed: 26 (6 ULg)
See detailPrécarité psycho-sociale différentielle des hommes et des femmes
Born, Michel ULg; Gavray, Claire ULg

in Cahiers de l'IPSA (1996), 19

Detailed reference viewed: 34 (6 ULg)
Full Text
Peer Reviewed
See detailProbing the Surface Molecular Structure in the UPS Spectra of Octadecanethiol and 1-Cyclohexyl-12-dodecanethiol Self-Assembled on Gold
Duwez, Anne-Sophie ULg; Riga, Joseph; Han, Bo-Ying et al

in Journal of Electron Spectroscopy & Related Phenomena (1996), 81

Detailed reference viewed: 4 (0 ULg)
Peer Reviewed
See detailEffect Of Propylene Glycol Supplementation Around Parturition On Milk Yield, Reproduction Performance And Some Hormonal And Metabolic Characteristics In Dairy Cows
Formigoni, A.; Cornil, Mc.; Prandi, A. et al

in Journal of Dairy Research (1996), 63(1),

Detailed reference viewed: 45 (3 ULg)
See detailEtat-providence et efficacité économique
Gathon, Henry-Jean ULg; Pestieau, Pierre ULg

in Revue Française d'Economie (1996), XI, 2(Printemps), 29-44

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailLa myxomatose amyxomateuse: isolement de trois souches en Belgique
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

Detailed reference viewed: 53 (9 ULg)
Full Text
Peer Reviewed
See detailPrognostic Significance of bcl-2 Protein Expression in Aggressive Non-Hodkin's Lymphoma
Hermine, Olivier; Haioun, Corinne; Lepage, Eric et al

in Blood (1996)

Detailed reference viewed: 18 (3 ULg)
Peer Reviewed
See detailEnrico Mattioda, Teorie della tragedia nel settecento, Modena, Mucchi, 1994, 366
Curreri, Luciano ULg

in Franco-Italica (1996), 9

Detailed reference viewed: 20 (0 ULg)
Peer Reviewed
See detailDesign and modeling of new platelet-activating factor antagonists.2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkoxymethylpiperazines
Tavet, Fabrice; Lamouri, Aazdine; Heymans, Françoise et al

in Journal of Lipid Mediators and Cell Signalling (1996), 15

Detailed reference viewed: 31 (1 ULg)
Peer Reviewed
See detailTomographie a emission de positons dans l'evaluation de l'extension ganglionnaire intrathoracique du cancer bronchique non petites cellules. Etude preliminaire chez 30 patients.
Bury, Thierry ULg; CORHAY, Jean-Louis ULg; Paulus, P et al

in Revue des Maladies Respiratoires (1996), 13(3), 281-286

Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some ... [more ▼]

Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some lung cancer patients are found to have unresectable disease at surgery. In contrast to CT scan or MR imaging, which depend primarily on anatomic and morphological criteria, positron emission tomography (PET) with 18fluorodeoxyglucose (FDG) depends mainly of the metabolic characteristics of a tissue for the diagnosis of disease. We perform a prospective study to compare FDG-PET and CT of the thorax in the presurgical assessment of the mediastinum in patients with newly diagnosed non-small cell lung cancer. Thirty patients have been included. CT and PET-scans were interpreted separately and results were compared to surgical staging during thoracotomy. In assessing mediastinal involvement, CT scan had a sensitivity of 56% and a specificity of 64%. For diagnosis mediastinal nodal disease, FDG-PET was 87% sensitive and 78% specific. Its positive predictive value was 82%, and the negative value was 83%. In conclusion, our preliminary results show that FDG-PET appears more accurate than CT in staging of mediastinal non-small cell lung cancer. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailIn situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male syrian hamsters
Nonclercq, D.; Reverse, D.; Toubeau, G. et al

in Biology of Reproduction (1996), 55(6), 1368-1376

Testis regression was induced in male Syrian hamsters by chronic exposure to diethylstilbestrol (DES), an estradiol-1713 agonist. Experimental groups (n = 4-5) were killed at increasing time intervals ... [more ▼]

Testis regression was induced in male Syrian hamsters by chronic exposure to diethylstilbestrol (DES), an estradiol-1713 agonist. Experimental groups (n = 4-5) were killed at increasing time intervals over a period of 6 mo after initiation of treatment. Apoptosis in testes was demonstrated by in situ analysis of DNA fragmentation. Cell proliferation was monitored by immunostaining nuclei of S-phase cells after pulse labeling with 5-bromo-2'-deoxyuridine. Levels of FSH and testosterone, measured by RIA, fell rapidly in DES-treated hamsters. In parallel, testis weight and seminiferous tubule area underwent an 80% decrease during the first 2 wk of DES administration. The composition of seminiferous epithelium was also drastically affected by DES, since it became progressively confined to Sertoli cells, spermatogonia, and spermatocytes. Testis regression was associated with an important increase of apoptosis, which started 3 days after the beginning of DES administration. Apoptosis was still 10- to 50-fold higher than in control testes by the end of treatment; it affected primarily spermatocytes and, to a much lesser extent, spermatogonia. Cell proliferation was not inhibited by chronic DES administration. In conclusion, these data indicate that apoptosis can by itself account for estrogen-induced testis regression. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailMuscle protein metabolism in relation to growth rate in double muscled Belgian Blue bulls: an integrated approach
Van Eenaeme, Christian ULg; Hornick, Jean-Luc ULg; Baldwin, Paule et al

in Mededelingen van de Faculteit van Landbouwwetenschappen, Rijksuniversiteit, Gent (1996), 61/4a

Detailed reference viewed: 9 (1 ULg)
Full Text
Peer Reviewed
See detailT92-0045: Interlaboratory quality control on Tpot measurements
Coucke, Philippe ULg; Beer, K.; Bernier, J. et al

in International Journal of Radiation, Oncology, Biology, Physics (1996), 36(1(supp1)), 384

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailIs IL-6 capable to modify chondrocyte metabolism ?
Henrotin, Yves ULg; Labasse, A; Jaspar, JM et al

in Clinical Rheumatology (1996), 15

Detailed reference viewed: 3 (2 ULg)
See detailCuba in tijden van periodo especial
Vanden Berghe, Kristine ULg

in Romaneske (1996), 21(1), 40-44

Detailed reference viewed: 52 (0 ULg)
Peer Reviewed
See detailComparative genome organization of vertebrates. The First International Workshop on Comparative Genome Organization.
Andersson, L.; Archibald, A.; Ashburner, M. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1996), 7(10), 717-34

Detailed reference viewed: 3 (1 ULg)
See detailLa dérivée schwarzienne
Bair, Jacques ULg; Haesbroeck, Gentiane ULg

in Mathématique et Pédagogie (1996), 108

Dans cette note est introduit le concept de dérivée schwarzienne pour une fonction réelle univariée. Diverses propriétés et applications sont également proposées.

Detailed reference viewed: 99 (0 ULg)
Full Text
Peer Reviewed
See detailDensité osseuse fémorale et carence vitaminique D dans une population de femmes âgées
DEROISY; Pirenne, H; FREDERICK, Isabelle ULg et al

in Archives of Public Health (1996), 53(S1), 37

Detailed reference viewed: 11 (2 ULg)
Peer Reviewed
See detailEthnic Mobilisation, Multiculturalism and the Political Process in two Belgian Cities : Antwerp and Liège
Martiniello, Marco ULg; Blommaert, Jan

in Innovation in Social Sciences Research (1996), 9(1), 51-74

Detailed reference viewed: 44 (4 ULg)
Peer Reviewed
See detailLes maladies virales chez le lapin européen (Oryctolagus cuniculus)
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

Detailed reference viewed: 16 (0 ULg)
Peer Reviewed
See detailCloning and Sequencing of the Dnak Locus in Streptomyces Coelicolor A3(2)
Brans, Alain ULg; Loriaux, Axelle; Joris, Bernard ULg et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1996), 6(3), 179-84

The dnaK operon of Streptomyces coelicolor A3(2) was cloned by the DNA-probing method using synthetic oligonucleotides designed on the basis of two of the most conserved regions in 30 different DnaK ... [more ▼]

The dnaK operon of Streptomyces coelicolor A3(2) was cloned by the DNA-probing method using synthetic oligonucleotides designed on the basis of two of the most conserved regions in 30 different DnaK proteins (HSP70). The isolated insert-a BamHI 5.6-kb fragment-was sequenced and shown to contain three open-reading frames organized in an operon and coding for proteins analogous to DnaK, GrpE and DnaJ, successively. [less ▲]

Detailed reference viewed: 20 (7 ULg)
Peer Reviewed
See detailComparison of food conversion by the Pirapatinga Piaractus brachypomus under different times of feeding
Baras, E.; Mélard, Charles ULg; Grignard, J. C. et al

in Progressive Fish-Culturist (1996), 58

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailPseudoaneurisma gigante del ventriculo izquierdo
Olivieri, E.; Guessaghi, R.; Chavin, A. et al

in Prensa Medica Argentina (1996), 83(10), 919-924

A 85 years old patient was hospitalized because of thoracic pain, lasting since three months. He suffered of Parkinson's disease and he was a smoker. The pain increased with cough and Vansalva's test. His ... [more ▼]

A 85 years old patient was hospitalized because of thoracic pain, lasting since three months. He suffered of Parkinson's disease and he was a smoker. The pain increased with cough and Vansalva's test. His left arm was cianotic. An arterial obstruction was suspected. Dopler ultrasound of the left arm confirmed a partial obstruction of the left axillar artery. Surprisingly, thoracic scan and MRI found an important cardiomegaly. The heart was in contact with the diaphragmatic and gastric region. Ecocardiography confirmed a 7 cm pseudo aneurysm of the left ventricle. Coronarography showed extreme hypokinesia of the left ventricle. There was also an obstruction of the right coronary and 50 % stenosis of the left coronary. Pseudo aneurysm was a complication of myocardial infarction of the left ventricle. Surgery was offered to the patient, but he declined the intervention. He was dismissed with medical treatment and anticoagulation. The patient deceased three months later. [less ▲]

Detailed reference viewed: 44 (4 ULg)
Full Text
Peer Reviewed
See detailDe la spécificité du discours comique
Defays, Jean-Marc ULg

in Français Moderne (Le) (1996), LXIV

Detailed reference viewed: 35 (1 ULg)
Peer Reviewed
See detailUn nouveau département de français à l'Université de Liège : ses précédents, ses missions, ses projets, son équipe
Defays, Jean-Marc ULg

in Français 2000 : Le point sur le Français langue étrangère (1996), (150-151), 60-62

Detailed reference viewed: 6 (1 ULg)
Full Text
Peer Reviewed
See detailGlucose, alpha-amino nitrogen and amino acid exchange across the hindlimb in young bulls maintained at two growth rates
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Gauthier, Sabine et al

in Canadian Journal of Animal Science (1996), 76(2), 193-202

The effect of growth rate and protein supplementation on muscle metabolism of eight bulls from the Belgian Blue breed, double-muscled type, was investigated by the arterio-venous difference technique. A ... [more ▼]

The effect of growth rate and protein supplementation on muscle metabolism of eight bulls from the Belgian Blue breed, double-muscled type, was investigated by the arterio-venous difference technique. A low growth (LG) group was maintained at a low growth rate over 36 d, and a rapid growth (RG) group for 28 d before receiving a fattening diet allowing for a rapid growth. At the end of the RG period the RG bulls received a supplement of protected soybean meal. Animals were fitted with an aortic ultrasonic blood flow probe and with catheters in the aorta and the vena cava. The blood flow in the hindlimbs of bulls varied greatly by time of the day but was higher in the RG group. The RG group had a higher arterio-venous difference (AVD) and uptake of alpha-amino nitrogen while AVD in essential amino acids was four times higher and uptake eight times higher. Significant higher AVD or uptake was observed in individual amino acids such as leucine, isoleucine and lysine. The supplementation with protected soybean meal had significant negative effect on the uptake of several amino acids. It was concluded that caution should be exercised when measuring punctually blood flow in muscle tissue, for example by dilution techniques. At high growth rate, the requirements for amino acids are larger than for glucose. Excess protein provides no additional benefit. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Peer Reviewed
See detailIdentification of antigens recognized in the developing mouse brain by the RC2 antibody, a marker of radial glia
Leprince, Pierre ULg; Chanas-Sacre, G.; Wattiez, R. et al

in International Journal of Developmental Neuroscience (1996), 14(Sup. 1), 84

Detailed reference viewed: 23 (8 ULg)
Full Text
Peer Reviewed
See detailRéactions physiologiques face à des conditions extrêmes de chaleur et d'humidité relative. Etude de la récupération après l'exercice
Art, Tatiana ULg; Votion, Dominique ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (1996), 28

The purpose of this study was to follow the recovery of horses during 1hour after treadmill exercise performed either in temperated atmospheric conditions (TC) (ambient temperature: 15°C; relative ... [more ▼]

The purpose of this study was to follow the recovery of horses during 1hour after treadmill exercise performed either in temperated atmospheric conditions (TC) (ambient temperature: 15°C; relative humidity: 55%) or in hot and humid conditions (HHC) (ambient temperature: 30°C; relative humidity: 75%). Five healthy fit standardbred horses (493± 14 kg; 4± 0,5 yrs) were investigated twice at eight days interval, in TC and in HHC. Some ventilatory and cardiorespiratory measurements were made during a standardised treadmill exercise test (SET), other measurements, i.e. cardiac and respiratory frequencies and rectal temperature, during a 1-hour recovery period. The SET consisted in 8 min warm-up and in 8 min exercise (1 min at 1,7, 4, 7, 8, 9 and 10 m/sec and 2 min at 4 m/sec with a 6% (3.4°) slope). Venous blond was sampled before, 2 min, 60 min and 48 hours after the completion of the test for biochemical analysis, namely plasma electrolytes and enzymatic activities. Exercising in HHC induced a reduction of the aerobic metabolism to the total energy requierement, i.e. a 20 % decrease of VO, and 55 % increase in lactate, as well as a decrease in VE. The increase in rectal and skip temperature, the dehydration and the weight loss were higher in HHC than in TC. During the recovery period the HR and f remained higher up to 30 minutes after the end of the SET in HHC while the rectal temperature remained higher up to 60 min after the end of this test. Sa, despite the fact that our horses recovered in TC after exercising in HHC, there were significant differences between their physiological parameters measured during the recovery. This means that the recovery in air-conditionned unit would probably be an insufficient measure to ensure an adequate cooling of the horses and justify consequently the adaptations proposed by the FEI, i.e. the decrease of the distance of the run and the increase of the lime devoted to the hall between phases [less ▲]

Detailed reference viewed: 126 (3 ULg)
See detailVérification microbiologiques et sérologiques des donneurs de cornées
Weekers, J. F.; Melin, Pierrette ULg; Lejeune, Tony ULg et al

in Bulletin de la Société Belge d'Ophtalmologie (1996), 260

A study was made during 1994 about microbiological contamination on the donor eyes before enucleation of whole globe. We studied the efficiency of the decontamination method by checking sterility of ... [more ▼]

A study was made during 1994 about microbiological contamination on the donor eyes before enucleation of whole globe. We studied the efficiency of the decontamination method by checking sterility of corneal storage medium after two days. We give results of serological tests on 252 donors. [less ▲]

Detailed reference viewed: 18 (5 ULg)
Full Text
Peer Reviewed
See detailPrimary Systemic Amyloidosis - A report of 2 cases
Dezfoulian, Bita ULg; Arrese Estrada, Jorge ULg; Fernandez, A. et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1996), 192

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection ... [more ▼]

We report 2 cases of primary systemic amyloidosis. A monoclonal gammopathy was confirmed at the postmortem examination of the first patient. An extensive search for evidence of chronic infection, inflammation, neoplasms and paraproteinemia was conclusively negative in the other patient. The recognition of cutaneous signs of primary systemic amyloidosis is crucial to insure a rapid management aimed at postponing the fatal issue of the disease. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailManifestaciones cardiovasculares en el SIDA
Valdes, E. F.; Rostello, E.; Villanueva, H. R. et al

in Prensa Medica Argentina (1996), 83

Cardiovascular complications in acquired immunodeficiency syndrome. AIDS miocardiopathy has been described since 1983. Physiopathologic events leading to AIDS myocardiopathy are largely unknown: viral ... [more ▼]

Cardiovascular complications in acquired immunodeficiency syndrome. AIDS miocardiopathy has been described since 1983. Physiopathologic events leading to AIDS myocardiopathy are largely unknown: viral miocardiopathy, cytokines induced lesions, nutritional status, microvascular and ischemic miocadiopathy have been suspected. We describe a consecutive series of 50 patients (43 males, 7 women) with HIV infection and severe immunodepression (CD4<200/ml) that had clinical, ECG and echocardiographic evaluation. There were 24 drug addicted patients, 17 homosexual patients, and 10 heterosexuals. Some of these patients had the following opportunistic infections: tuberculosis (n=20), Pneumocystis carinii (n=9), Criptocococis (n=9), oropharyngeal candidosis (n=5), toxoplasmosis (n=5), histoplasmosis (n=1) and Kaposi’s sarcoma (n=2). After clinical evaluation 15/50 patients had some kind of cardiovascular complication: 6 patients had congestive heart failure, 5 patients presented with pericardial effusion, one patient has a reversible cardiac arrest, and one patient had pulmonary valvular endocarditis. After Doppler echocardiographic evaluation (according to the American echocardiography association), we found 20 patients with left ventricular diastolic dysfunction, 9 patients with right ventricular diastolic dysfunction and 6 patients with left ventricular systolic dysfunction. In conclusion, our series found left diastolic dysfunction in nearly 40 % of cases and cardiavasular events (pericarditis, heart congestive failure, arrhythmias) in 26% of cases. Cardiovascular complications have prognostic implications in AIDS and shoul be early detected. Further pathological and immunohistochemical studies are needed to clarify the phyiopathological etiologies in AIDS miocardiopathy. [less ▲]

Detailed reference viewed: 35 (7 ULg)
Full Text
Peer Reviewed
See detailNouveaux bisphosphonates dans l’ostéoporose : craintes et espoirs
Reginster, Jean-Yves ULg

in Revue du Rhumatisme (1996), 63(7-8), 545-548

Detailed reference viewed: 5 (1 ULg)
Full Text
Peer Reviewed
See detailThree hTIM mutants that provide new insights on why TIM is a dimer
Mainfroid, Véronique; Terpstra, Peter; Beauregard, Marc et al

in Journal of Molecular Biology (1996), 257(2), 441-56

Human triosephosphate isomerase (hTIM), a dimeric enzyme, was altered by site-directed mutagenesis in order to determine whether it can be dissociated into monomers. Two hTIM mutants were produced, in ... [more ▼]

Human triosephosphate isomerase (hTIM), a dimeric enzyme, was altered by site-directed mutagenesis in order to determine whether it can be dissociated into monomers. Two hTIM mutants were produced, in which a glutamine residue was substituted for either Met14 or Arg98, both of which are interface residuces. These substitutions strongly interfere with TIM subunit association, since these mutant TIMs appear to exist as compact monomers in dynamic equilibrium with dimers. In kinetic studies, the M14Q mutant exhibits significant catalytic activity, while the R98Q enzyme is inactive. The M14Q enzyme is nevertheless much less active than unmutated hTIM. Moreover, its specific activity is concentration dependent, suggesting a dissociation process in which the monomers are inactive. In order to determine the conformational stability of the wild-type and mutant hTIMs, unfolding of all three enzymes was monitored by circular dichroism and tryptophan fluorescence spectroscopy. In each case, protein stability is concentration dependent, and the unfolding reaction is compatible with a two-state model involving the native dimer and unfolded monomers. The conformational stability of hTIM, as estimated according to this model, is 19.3 (+/-0.4) kcal/mol. The M14Q and R98Q replacements significantly reduce enzyme stability, since the free energies of unfolding are 13.8 and 13.5 (+/- 0.3) kcal/mol respectively, for the mutants, A third mutant, in which the M14Q and R98Q replacements are cumulated, behaves like a monomer. The stability of this mutant is not concentration-dependent, and the unfolding reaction is assigned to a transition from a folded monomer to an unfolded monomer. The conformational stability of this double mutant is estimated 2.5 (+/-0.1) kcal/mol. All these data combined suggest that TIM monomers are thermodynamically unstable. This might explain why TIM occurs only as a dimer. [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
See detailCartes de contrôle : combinaison de résultats, données corrélées ou multivariées
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (3), 1-37

This note first describes moving average, exponentially weighted moving average and cumulative sum control charts. Then, control charts for autocorrelated and for multivariate data are examined. Minitab ... [more ▼]

This note first describes moving average, exponentially weighted moving average and cumulative sum control charts. Then, control charts for autocorrelated and for multivariate data are examined. Minitab outputs are given for these control charts. [less ▲]

Detailed reference viewed: 34 (1 ULg)
Full Text
See detailCartes de contrôle : les cartes de Shewhart.
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (2), 41

This note describes the SHEWHART control charts for subgroup means, standard deviation, medians, ranges, proportions of defectives, numbers of defectives and numbers of defects. Minitab and SAS outputs ... [more ▼]

This note describes the SHEWHART control charts for subgroup means, standard deviation, medians, ranges, proportions of defectives, numbers of defectives and numbers of defects. Minitab and SAS outputs are given for all these charts. [less ▲]

Detailed reference viewed: 48 (0 ULg)
Peer Reviewed
See detailSaint Remacle, évangélisateur en Ardenne (ca. 650). Mythe et réalité
George, Philippe ULg

in Bulletin de l'Institut Historique Belge de Rome (1996), XXXVIII

Detailed reference viewed: 18 (3 ULg)
Full Text
Peer Reviewed
See detailType II to type I transformation of chronically stimulated goat latissimus dorsi muscle: a histoenzymological, biochemical, bioenergetic, and functional study.
Radermacker, M. A.; Focant, B.; Hautecler, T. et al

in European Surgical Research = Europäische Chirurgische Forschung = Recherches Chirurgicales Européennes (1996), 28

Five goat latissimus dorsi muscles (LDM) were submitted to a progressive chronic electrostimulation program to reach an integrated understanding of the fast-to-slow transformation process in large mammals ... [more ▼]

Five goat latissimus dorsi muscles (LDM) were submitted to a progressive chronic electrostimulation program to reach an integrated understanding of the fast-to-slow transformation process in large mammals. LDM were regularly sampled and followed during a period of 8 months. Each sample was simultaneously assessed for histoenzymological study, myosin and LDH isoforms and bioenergetic capacities [NADH dehydrogenase cytochrome c oxidoreductase (NADH Cyt c OR), succinate dehydrogenase cytochrome c oxidoreductase (Succ Cyt c OR), cytochrome c oxidase (Cyt c Ox) and LDH]. Such muscles were also tested with and without completion of II to I transformation for their mechanical properties in isometric and isotonic strain gauge testing. The conversion of fast-to-slow myosin monitored by heavy chain (HC I) and light chain slow component (LC2s) began a few days after stimulation and was almost 100% after 100 days. The H-LDH isoforms evolved similarly but did not reach 100% conversion after 200 days. The activity of respiratory chain oxidases increased within 36 h but to a variable extent and peaked after 32 days, corresponding to a 75% transformation of myosin compared to initial levels. NADH Cyt c OR, Succ Cyt c OR, and Cyt c Ox, respectively increased 10-, 5- and 5-fold. These activities then significantly decreased before the completion of the myofibrillar transformation and reached a plateau with stable activities that remained 2- to 3-fold higher than the unstimulated LDM. LDH activity sharply decreased until day 62 (5-fold) and then plateaued. Functionally, muscle showed a reduced speed of contraction and moderate reduction in power output but had become fatigue-resistant. This study documents the transformation process in large mammals and suggests the dynamic relation between workload, aerobic-anaerobic metabolism and the contractile myofibrillar system. [less ▲]

Detailed reference viewed: 18 (7 ULg)
Peer Reviewed
See detailCardiovascular risk factors in children from the Belgian province of Luxembourg. The Belgian Luxembourg Child Study.
Guillaume, Michèle ULg; Lapidus, L.; Beckers, L. et al

in American Journal of Epidemiology (1996), 144(9), 867-80

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children ... [more ▼]

The Province of Luxembourg is an area in Belgium with a high prevalence of risk factors for cardiovascular disease and non-insulin-dependent diabetes mellitus among adults. In the present study, children in the age groups 6-8, 8-10, and 10-12 years were selected at random from school classes (n = 1,028), with a participation rate of 70.3%. Anthropometric factors, blood pressure, and fasting blood glucose, plasma cholesterol, triglyceride, and insulin levels were measured in 1992. All anthropometric and metabolic variables increased with age, except for waist: hip circumference ratio in boys and cholesterol in girls. In the oldest group, girls who had passed menarche were taller and heavier and had greater skinfold, body mass index, insulin, and systolic blood pressure values but lower total cholesterol levels and waist: hip ratios than girls who had not passed menarche. Boys had lower skinfolds and higher waist: hip ratios than girls in all age groups, and were significantly shorter and lighter in the oldest age group. There was no difference in body mass index between the two sexes. Girls had higher triglyceride and insulin levels in the 10- to 12-year age group, lower blood glucose values in the 8-10 and 10-12 age groups, and lower diastolic blood pressures in the 8-10 age group. Obesity, blood glucose, triglycerides, insulin, and blood pressure were highly interrelated. Cholesterol, triglycerides, insulin, and blood pressure values were all among the highest of values previously reported in other studies. The deciles of body mass index above 50 appeared to be particularly elevated, suggesting that obesity, when present, was pronounced in this population of children. These findings suggest an accumulation of genetic susceptibility to cardiovascular disease and non-insulin-dependent diabetes mellitus in this stable, ethnically homogeneous, and rather isolated part of continental Europe. [less ▲]

Detailed reference viewed: 10 (5 ULg)
Peer Reviewed
See detailCompte rendu de J.-L. LEMAITRE, Le Limousin monastique
George, Philippe ULg

in Moyen Age (Le) (1996)

Detailed reference viewed: 6 (0 ULg)
Full Text
See detailLa classification numérique : principes et applications
Palm, Rodolphe ULg

in Notes de Statistique et d'Informatique (1996), (1), 28

The principles of some clustering techniques are described and illustrated by an example. The data consist of chemical contents for 45 types of mineral water.

Detailed reference viewed: 134 (5 ULg)
Peer Reviewed
See detailMinority Rights in Europe de H. Miall (ed)
Martiniello, Marco ULg

in Ethnic and Racial Studies (1996), 19(2), 446-447

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailTheory of laser-induced two-step electron-ion recombination
Schlagheck, Peter ULg; Maragakis, P.; Lambropoulos, P.

in Zeitschrift für Physik. D, Atoms, Molecules, and Clusters (1996), 37(1), 19-27

A theoretical framework for the quantitative interpretation of laser-induced electron-ion recombination is presented in terms of the density matrix taking into account stochastic bandwidth and pulse ... [more ▼]

A theoretical framework for the quantitative interpretation of laser-induced electron-ion recombination is presented in terms of the density matrix taking into account stochastic bandwidth and pulse duration of the laser. The theory deals with recombination induced from the continuum into one group of states by one laser and further stabilized into a lower group of states by a second laser. Rate equations are then derived from the complete density matrix, and the conditions for their validity are discussed. Both density matrix and rate equations are applied to the interpretation of a recent experiment with equally good agreement. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailL’immigration. De l’homme seul à la famille de A. Zerhaoui
Martiniello, Marco ULg

in Revue Européenne des Migrations Internationales (1996), 12(1), 224-225

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailEndometrial laser interstitial hyperthermy: a potential modality for endometrial ablation.
Donnez, Jacques; Polet, Roland; Mathieu, Pierre-Emmanuel et al

in Obstetrics & Gynecology (1996), 87(3), 459-64

This study was undertaken to evaluate the efficacy and safety of an intrauterine device designed for endometrial ablation by Nd-YAG laser interstitial hyperthermy. Eight hysterectomy specimens were ... [more ▼]

This study was undertaken to evaluate the efficacy and safety of an intrauterine device designed for endometrial ablation by Nd-YAG laser interstitial hyperthermy. Eight hysterectomy specimens were treated in vitro with an output power of 30 W for 5 minutes; tissue temperatures, recorded by thermocouples, were plotted to draw time-temperature and time-distance curves. As a preliminary series, ten patients were treated, with the first five subjected to local temperature monitoring; all ten were followed-up for 6-17 months. Immediate and delayed (6 weeks) histologic data were obtained. The intramural temperature at 6 mm from the fibers ranged from 55-60C). In vivo, the cooling effect of the arterial blood flow lowered the serosal temperatures under 41C. The histologic data and the hysterographic pictures suggest that endometrial ablation was effective. This new device does not require distending medium, hysteroscopic control, or high-powered Nd-YAG laser machines. Preliminary long-term results suggest that the device could be used for endometrial ablation. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailDu gang au groupe social: une analyse socio-préventive
Comeron, Manuel ULg

in Cahiers de la Sécurité (1996)

Au delà d'une enceinte ludique, le stade de football est le théatre d'un supporterisme démonstratif: agressivité des ultra ou hooligan, exaspération partisane, foule. Le supporter est l'objet d'étude de ... [more ▼]

Au delà d'une enceinte ludique, le stade de football est le théatre d'un supporterisme démonstratif: agressivité des ultra ou hooligan, exaspération partisane, foule. Le supporter est l'objet d'étude de la recherche qui évalue aussi les politiques publiques de prévention. [less ▲]

Detailed reference viewed: 67 (10 ULg)
Peer Reviewed
See detailLe chaponnage, une technique qui revient à la mode!
Marlier, Didier ULg; Vindevogel, Henri ULg

in Annales de Médecine Vétérinaire (1996), 140

Detailed reference viewed: 469 (0 ULg)
Full Text
Peer Reviewed
See detailSelection of hammerhead ribozymes for optimum cleavage of interleukin 6 mRNA.
Hendrix, Chris; Anne, J; Joris, Bernard ULg et al

in Biochemical Journal (1996), 314 ( Pt 2)

Four GUC triplets in the coding region of the MRNA of interleukin 6 (IL-6) were examined for their suitabilty to serve as a target for hammerhead ribozome-mediated cleavage. This selection procedure was ... [more ▼]

Four GUC triplets in the coding region of the MRNA of interleukin 6 (IL-6) were examined for their suitabilty to serve as a target for hammerhead ribozome-mediated cleavage. This selection procedure was performed with the intention to downregulate IL-6 production as a potential treatment of those diseases in which IL-6 overexpression is involved. Hammerhead ribozymes and their respective short synthetic substrates (19-mers) were synthesized for these four GUC triplets. Notwithstanding the identical catalytic core sequences, the difference in base composition of the helices involved in substrate binding caused substantial variation in cleavage activity. The cleavage reactions on the 1035 nucleotide IL-6 mRNA transcript revealed that two ribozymes were able to cleave this substrate, showing a decrease in catalytic efficiency to 1/30 and 1/300 of the short substrate. This study indicates that the GUC triplet located at nucleotide 510 of the mRNA of IL-6 is the best site for hammerhead ribozyme-mediated cleavage. We suggest that in future targeting of chemically modified hammerhead ribosomes for cleavage of IL-6 RNA should be directed at this location. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailA Morphometric and Functional Study of the Toxicity of Atmospheric Ammonia in the Extrathoracic Airways in Pigs
Urbain, B.; Gustin, Pascal ULg; Charlier, G. et al

in Veterinary Research Communications (1996), 20(4), 381-399

The effects of atmospheric ammonia (NH3) on the nasal and tracheal mucosa of pigs were investigated by morphometric and functional methods. Pigs were exposed to four concentrations of NH3 [5 (control), 25 ... [more ▼]

The effects of atmospheric ammonia (NH3) on the nasal and tracheal mucosa of pigs were investigated by morphometric and functional methods. Pigs were exposed to four concentrations of NH3 [5 (control), 25, 50 and 100 ppm] for 6 days in a specially designed air-pollutant exposure chamber. Samples were taken from the turbinates and the trachea, and the respiratory mucosa was examined by light and scanning electron microscopy. Dose-response curves to carbachol and isoproterenol were constructed using isolated strips of tracheal smooth muscle, with or without epithelium. In pigs exposed to ammonia, considerable mucosal injuries were observed in the turbinates but not in the trachea. The number of neutrophils in the epithelial layer and in the lamina propria, and epithelial hyperplasia were closely and significantly correlated with the concentrations of ammonia (r = 0.894, p < 0.001; r = 0.727, P < 0.001; and r = 0.818, p < 0.001, respectively). Except for the lamina propria, all these changes were significant (p < 0.05) at ammonia concentrations as low as 25 ppm. The percentage of the surface of the turbinate mucosa that was ciliated tended to decrease with increasing ammonia concentration (r = 0.439, p < 0.082). Ammonia induced smooth-muscle hyperresponsiveness to carbachol with a close linear correlation between individual values of the carbachol-induced maximal effect and the NH3 concentrations (r = 0.526, p < 0.003). While mechanical destruction of the epithelium induced an increase in Emax in the control group, no difference was observed between the intact and denuded strips from animals exposed to ammonia. The response to isoproterenol was not influenced by ammonia. It was concluded that quantitative histological analysis of the inflammatory infiltration and epithelial hyperplasia in the turbinates is a useful tool for quantifying the effects of atmospheric pollutants in pigs; a 6-day exposure to ammonia induces nasal irritation and functional disturbances of the tracheal smooth-muscle contractions at concentrations as low as 25 ppm [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailParadoxical Sleep Deprivation Increases the Content of Glutamate and Glutamine in Rat Cerebral Cortex
Bettendorff, Lucien ULg; Sallanon-Moulin, M.; Touret, Monique et al

in Sleep (1996), 19(1), 65-71

We investigated the influence of the sleep/waking cycle, the effects of paradoxical sleep deprivation (PSD) and of the vigilance-promoting drug modafinil on the amino acid contents of rat brain cortex. No ... [more ▼]

We investigated the influence of the sleep/waking cycle, the effects of paradoxical sleep deprivation (PSD) and of the vigilance-promoting drug modafinil on the amino acid contents of rat brain cortex. No significant nycthemeral variations in amino acid levels could be detected. PSD (12-24 hours), using the water tank method, significantly increased the levels of glutamate and glutamine. The increase was still observed after the sleep rebound period. gamma-Aminobutyric acid (GABA) levels did not change significantly during the instrumental sleep deprivation but increased during the rebound period. Control experiments indicate that the increase in glutamate and glutamine levels is due to PSD rather than to the stress associated with the experimental procedure. The increase in glutamate content cannot arise only from transamination reactions, because the levels of other amino acids (such as aspartate) did not decrease. Modafinil treatment did not significantly modify the brain cortex content of any of the amino acids tested. [less ▲]

Detailed reference viewed: 31 (1 ULg)
Peer Reviewed
See detailCompte rendu de l'ouvrage de P. Contamine, Des pouvoirs en France. 1300/1500
Marchandisse, Alain ULg

in Le Moyen Âge (1996), 102

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailThe riddle of formycin A insulinotropic action
Malaisse, W. J.; Lebrun, P.; Pirotte, Bernard ULg et al

in Biochemical and Molecular Medicine (1996), 57

Detailed reference viewed: 9 (1 ULg)
Peer Reviewed
See detailLes canaux potassiques ATP-dépendants et la sécrétion d'insuline: effets du BPDZ 62
Ouedraogo, R.; Pirotte, Bernard ULg; Antoine, M. H. et al

in Journal de Pharmacie de Belgique (1996), 51

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailThe efficacy in vitro and in vivo of bacteriocin against Erwinia amylovora : comparison of biological and chemical control of fire blight
Jabrane, A.; Deckers, T.; Ledoux, L. et al

in Acta Horticulturae (1996), 411

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailMicrosatellite mapping of a major determinant of White Heifer Disease: the bovine roan locus
Charlier, Carole ULg; Denys, B.; Belanche, J. I. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (1996), 7

In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r + (black) and R (white ... [more ▼]

In the Belgian Blue Cattle breed, coat color variation is mainly under the influence of a single autosomal locus, the roan locus, characterized by a pair of codominant alleles: r + (black) and R (white). Heterozygous r + R animals have intermingled black and white hairs, yielding the ``blue'' phenotype typical of the breed. Major interest for the roan locus stems from its pleiotropic effect on fertility, owing to the critical role of the R allele in the determinism of White Heifer Disease. We describe the linkage mapping of the roan locus to bovine Chromosome (Chr) 5, in the interval between microsatellite markers BPI and AGLA293, with an associated lodscore of 11.2. Moreover, we map a candidate gene, the Steel locus coding for the mast cell growth factor, to bovine Chr 5. [less ▲]

Detailed reference viewed: 39 (3 ULg)
Full Text
Peer Reviewed
See detailBrain Levels of Thiamine and Its Phosphate Esters in Friedreich's Ataxia and Spinocerebellar Ataxia Type 1
Bettendorff, Lucien ULg; Mastrogiacomo, Frank; LaMarche, J. et al

in Movement Disorders : Official Journal of the Movement Disorder Society (1996), 11(4), 437-439

Decreased blood and cerebrospinal fluid levels of thiamine have been reported in patients with spinocerebellar ataxia disorders. To determine whether a thiamine deficiency is present in the brain, we ... [more ▼]

Decreased blood and cerebrospinal fluid levels of thiamine have been reported in patients with spinocerebellar ataxia disorders. To determine whether a thiamine deficiency is present in the brain, we measured levels of thiamine and its phosphate esters thiamine monophosphate (TMP) and thiamine diphosphate (TDP), in postmortem cerebellar and cerebral cortices of patients with Friedreich's ataxia (FA) and spinocerebellar ataxia type 1 (SCA1). Brain levels of free (nonphosphorylated) thiamine, TMP, TDP, and total thiamine in FA and SCA1 were, on average, not significantly different from control values. However, a nonsignificant trend was observed for slightly reduced levels of TDP and total thiamine in cerebellar cortex of the SCA1 patients, a finding that might be related to the severe neuronal damage in this brain area. We conclude that in FA, brain thiamine concentrations are normal, whereas in SCA1 the levels are, at most, only slightly reduced. [less ▲]

Detailed reference viewed: 13 (5 ULg)
Full Text
Peer Reviewed
See detailThe existence of an urban underclass in Belgium
Martiniello, Marco ULg

in New Community (1996), 22(4), 655-669

Detailed reference viewed: 19 (12 ULg)
Peer Reviewed
See detailBronchopulmonary and Disseminated Granulomatous Disease Associated with Aspergillus Fumigatus and Candida Species Infection in a Golden Retriever
Clercx, Cécile ULg; Mc Entee, Kathleen ULg; Snaps, Frédéric ULg et al

in Journal of the American Animal Hospital Association (1996), 32(2, Mar-Apr), 139-45

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed ... [more ▼]

A seven-year-old, female golden retriever was referred for a paroxysmal, chronic cough and dyspnea, dysphagia, facial pruritus, anterior uveitis, and deteriorating general condition. A severe, mixed interstitial and alveolar pattern, with poorly defined amorphous lesions, was seen on thoracic radiographs. Multiple, whitish nodules disseminated on the hyperemic respiratory mucosa were noted on bronchoscopy. Escherichia coli and Aspergillus fumigatus were cultured from the bronchoalveolar lavage. Granulomatous lesions in numerous organs were identified during necropsy, and Aspergillus fumigatus and Candida spp. were cultured from lung and kidney tissues. Microscopic granulomatous lesions were compatible with mycotic infection; however fungal organisms were not observed. [less ▲]

Detailed reference viewed: 20 (0 ULg)
Full Text
Peer Reviewed
See detailAgriculture et environnement : pour une sociologie des dispositifs
Mormont, Marc ULg

in Economie Rurale (1996), (No. 236), 28-36

An analytical model for the environmental regulation of agriculture under various aspects, such as the definition of environment, type of agricultural practice, incentives, scale of application and mode ... [more ▼]

An analytical model for the environmental regulation of agriculture under various aspects, such as the definition of environment, type of agricultural practice, incentives, scale of application and mode of administration, is presented. In a number of cases, technical, scientific, social and economic factors also have to be addressed (especially as regards the notion of uncertainty), which entails taking into account a series of heterogeneous and less obvious aspects. A new typology of institutional settings is therefore drawn up, which emphasizes the constraints present in any regulation. Particular reference is made to the EU. [less ▲]

Detailed reference viewed: 433 (9 ULg)
Full Text
Peer Reviewed
See detailSensitivity calculations and variance analysis in plant measurement reconciliation
Heyen, Georges ULg; Marechal, Eric; Kalitventzeff, Boris ULg

in Computers & Chemical Engineering (1996), 20(Suppl. A), 539-544

Analysis of the results of a data reconciliation program is made easier by extracting more information from the Jacobian matrix of the constraint equations. Standard deviation for all state variables ... [more ▼]

Analysis of the results of a data reconciliation program is made easier by extracting more information from the Jacobian matrix of the constraint equations. Standard deviation for all state variables (measured or not measured) is related to the standard deviation of measurements. Distinction between variables that are actually corrected by the validation process, and those that are merely derived from a single measurement is straightforward. Based on this information, decisions can be taken : deletion of unnecessary measurements, addition of new measurement points and their optimal selection, or identification of key measurements for which any enhancement of accuracy would result in significant improvement in the quality of the process validation. [less ▲]

Detailed reference viewed: 29 (5 ULg)