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See detailProtection possessoire et convention. Quand l'usufruitier devient bailleur
Lecocq, Pascale ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (1997)

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See detailGezonheidszorg : actuele standpunten. Diagnostiek van osteoporose
Devogelaer, JP; Reginster, Jean-Yves ULg; Raeman, F et al

in Tijdschrift voor Geneeskunde (1997), 53(10), 639-645

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See detailUse of the alpha parameter method to calculate matrix corrections for infinitely thick targets (TTPIXE) with two different incident beam energies
Delbrouck Habaru, J.; Roelandts, I.; Strivay, David ULg et al

in Nuclear Instruments & Methods in Physics Research Section B (1997), 129(1), 92-100

The alpha parameter correction method for calculating matrix effects in PIXE data does not require a priori knowledge of the major element composition of the matrix but implies the determination of a so ... [more ▼]

The alpha parameter correction method for calculating matrix effects in PIXE data does not require a priori knowledge of the major element composition of the matrix but implies the determination of a so-called alpha parameter linking two independent phenomena: X-ray absorption and proton energy loss. The method extrapolated to the infinitely thick targets (TTPIXE) has been previously studied using two PIXE measurements in two different geometric configurations. The present Study deals with the possibility of using pairs of PIXE measurements at two different energies to obtain the alpha corresponding to thick samples (TTPIXE). The experimental conditions and error minimization problems are discussed. General tables allowing an easy use of the method are presented. [less ▲]

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See detailNouvelles recherches dans le site magdalénien du Trou da Somme (Hastière)
López Bayón, Ignacio; Léotard, Jean-Marc; Otte, Marcel ULg et al

in Notae Praehistoricae (1997), 17

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See detailQuelques arthropodes de nos maisons
Loneux, Michèle ULg

in Cahiers d'Ethologie (1997), 17(1), 75-124

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See detailSelection of lumped parameter models to characterize vascular properties of pulmonary circulation
LAMBERMONT, Bernard ULg; GERARD, P; DETRY, Olivier ULg et al

in American Journal of Respiratory & Critical Care Medicine (1997), 2

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See detailThe Spectrum of Ne V
Bastin, Thierry ULg; Biémont, Emile ULg; Dumont, Paul-Dominique ULg et al

in Physica Scripta (1997), 55

A new investigation of the Ne V spectrum is reported. The beam-foil method has been used to produce spectra at two different energies (1.2 MeV and 2.5 MeV) between 450 and 11OOA Sixty-five lines of Ne V ... [more ▼]

A new investigation of the Ne V spectrum is reported. The beam-foil method has been used to produce spectra at two different energies (1.2 MeV and 2.5 MeV) between 450 and 11OOA Sixty-five lines of Ne V have been newly identified. Fifty levels have been determined for the first time and energies have been revised for seven levels. [less ▲]

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See detailCalibration of a finite element model for bolted endplate steel connections
Bursi, O.; Jaspart, Jean-Pierre ULg

in Journal of Constructional Steel Research (1997), 44(No 3), 225-262

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See detailThe Cloning And Sequencing Of An Ovine C-Myc Cdna
Kiermer, V.; Dequiedt, Franck ULg; Masengo, R. et al

in DNA Sequence : The Journal of DNA Sequencing & Mapping (1997), 7(3-4),

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See detailComparison between different methods of measurement of momentum and sensible heat fluxes over canopies.
Aubinet, Marc ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(1),

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See detailImage du mois. Syncope vasovagale en direct.
Scheen, André ULg; Marchand, Monique ULg; Juchmes, J.

in Revue Médicale de Liège (1997), 52(5), 315

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See detailLes différents vaccins disponibles contre la rhinotrachéite infectieuse bovine
Thiry, Etienne ULg; Lemaire, Mylène; Schynts, Frédéric et al

in Bulletin des Groupements Techniques Vétérinaires (1997), 4B

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See detailOrderly process of sequential cytokine stimulation is required for activation and maximal proliferation of primitive human bone marrow CD34+ hematopoietic progenitor cells residing in G0.
Ladd, A. C.; Pyatt, R.; GOTHOT, André ULg et al

in Blood (1997), 90(2), 658-68

Bone marrow (BM) CD34+ cells residing in the G0 phase of cell cycle may be the most suited candidates for the examination of cell cycle activation and proliferation of primitive hematopoietic progenitor ... [more ▼]

Bone marrow (BM) CD34+ cells residing in the G0 phase of cell cycle may be the most suited candidates for the examination of cell cycle activation and proliferation of primitive hematopoietic progenitor cells (HPCs). We designed a double simultaneous labeling technique using both DNA and RNA staining with Hoechst 33342 and Pyronin Y, respectively, to isolate CD34+ cells residing in G0(G0CD34+). Using long-term BM cultures and limiting dilution analysis, G0CD34+ cells were found to be enriched for primitive HPCs. In vitro proliferation of G0CD34+ cells in response to sequential cytokine stimulation was examined in a two-step assay. In the first step, cells received a primary stimulation consisting of either stem cell factor (SCF), Flt3-ligand (FL), interleukin-3 (IL-3), or IL-6 for 7 days. In the second step, cells from each group were washed and split into four or more groups, each of which was cultured again for another week with one of the four primary cytokines individually, or in combination. Tracking of progeny cells was accomplished by staining cells with PKH2 on day 0 and with PKH26 on day 7. Overall examination of proliferation patterns over 2 weeks showed that cells could progress into four phases of proliferation. Phase I contained cytokine nonresponsive cells that failed to proliferate. Phase II contained cells dividing up to three times within the first 7 days. Phases III and IV consisted of cells dividing up to five divisions and greater than six divisions, respectively, by the end of the 14-day period. Regardless of the cytokine used for primary stimulation, G0CD34+ cells moved only to phase II by day 7, whereas a substantial percentage of cells incubated with SCF or FL remained in phase I. Cells cultured in SCF or FL for the entire 14-day period did not progress beyond phase III but proliferated into phase IV (with <20% of cells remaining in phases I and II) if IL-3, but not IL-6, was substituted for either cytokine on day 7. G0CD34+ cells incubated with IL-3 for 14 days proliferated the most and progressed into phase IV; however, when SCF was substituted on day 7, cells failed to proliferate into phase IV. Most intriguing was a group of cells, many of which were CD34+, detected in cultures initially stimulated with IL-3, which remained as a distinct population, mostly in G0/G1, unable to progress out of phase II regardless of the nature of the second stimulus received on day 7. A small percentage of these cells expressed cyclin E, suggesting that their proliferation arrest may have been mediated by a cyclin-related disruption in cell cycle. These results suggest that a programmed response to sequential cytokine stimulation may be part of a control mechanism required for maintenance of proliferation of primitive HPCs and that unscheduled stimulation of CD34+ cells residing in G0 may result in disruption of cell-cycle regulation. [less ▲]

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See detailLa responsabilité pénale du réviseur d'entreprises : Épée de Damoclès ou Tigre de papier ?
Thirion, Nicolas ULg; Benoit-Moury, Anne

in Revue pratique des sociétés (1997), (2), 189-229

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See detailOxydation photochimique de lixiviats de décharge
Deswaef, Sophie; Baidak, Alexandre; Crine, Michel ULg

in Tribune de l'Eau (La) (1997), 590-591

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See detailThe two beta-lactamase genes of Streptomyces cacaoi, blaL and blaU, are under the control of the same regulatory system.
Magdalena, J; Gérard, Christine; Joris, Bernard ULg et al

in Molecular & General Genetics [=MGG] (1997), 255(2), 187-93

The production of beta-lactamase in Streptomyces cacaoi, which contains two beta-lactamase-encoding genes, blaL and blaU, is inducible by beta-lactam compounds. The two genes have been cloned ... [more ▼]

The production of beta-lactamase in Streptomyces cacaoi, which contains two beta-lactamase-encoding genes, blaL and blaU, is inducible by beta-lactam compounds. The two genes have been cloned independently in S. lividans TK24, a beta-lactamase-negative species. The blaU clone did not respond to the presence of beta-lactams, whereas the blaL clone appeared to be inducible in S. lividans. The latter clone contains two open reading frames, blaA and blaB, located just upstream of but transcribed divergently from blaL, which were shown to be required for the production as well as the induction of BlaL. The deduced BlaA protein belongs to the LysR family of transcription regulators. In order to examine the role of BlaA in regulation, we here report on over-expression of a GST-BlaA fusion protein in Escherichia coli and its use for antibody preparation. The GST-BlaA fusion protein was partially purified and bandshift assays showed that it bound the 197-bp blaL-blaA intergenic region. The BlaA DNA binding-site was further restricted to a 30-bp sequence containing a T-N11-A motif, a characteristic of LysR-type promoters. Another T-N11-A motif upstream of the blaU gene was also shown to bind BlaA. The affinities of these two T-N11-A motifs in BlaA binding were comparable. A plasmid bearing the blaU structural gene and the blaA-blaB regulatory region was constructed and shown to confer on an S. lividans host the capacity to produce inducible beta-lactamase. It can thus be concluded that the S. cacaoi blaL and blaU genes are controlled by the same regulatory system. [less ▲]

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See detailA new generation of hydrocolloid dressings in combination with topical corticosteroids in the treatment of psoriasis vulgaris
Dezfoulian, Bita ULg; de LA BRASSINNE, Michel ULg; Rosillon, D.

in Journal of the European Academy of Dermatology & Venereology (1997), 9

Aim : A clinical, randomized, parallel, multicenter study was undertaken to compare the efficacy and Ihe tolerability of two known steroid creams, betamethasone 17-valerate and clobetasol propionate ... [more ▼]

Aim : A clinical, randomized, parallel, multicenter study was undertaken to compare the efficacy and Ihe tolerability of two known steroid creams, betamethasone 17-valerate and clobetasol propionate, alone or left under a hydrocolloid dressing (Contreei'* Derma Cover), in the treatment of chronic plaques of psoriasis. Methods : A total of 70 patients with symmetrical localized psoriasis were divided randomly into two groups for the study. Each patient applied ihe corticosteroid preparation under Contreet° Derma Cover once a week on one plaque and the same topical corticosteroid alone h.i.d on the other plaque; the treatment lasted 3 weeks for betamethasone 17-valerate, and 2 weeks for clobetasol propionate. Results : The heahng rate reached 79% with the Contreet" combined treatment versus 15% (P < 0,0001) with the standard treatment for betamethasone 17-valeratc (group I) and Sb% versus 14*70 (P < 0. 0001) for clobetasol propionate (group It). The mean difference in healing rate was 65% {95% confidence interval (C.I), 46-84%) and 69% (95% CL, 50-87%) in groups I and II, respectively. Conclusion : The use of the new generation of hydrocolloid dressings in combination with steroid preparations can be considered as another therapeutic option for the treatment of chronic localized psoriatic lesions. Furthermore, with this method the amount of the topical corticosteroid used can be reduced. [less ▲]

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See detailA one-nucleotide difference in a cAMP and phorbol ester response element leads to differential regulation of the human chorionic somatomammotropin A and B gene transcription
Oury, Cécile ULg; Alsat, E.; Jacquemin, P. et al

in Journal of Molecular Endocrinology (1997), 18(2), 87-99

Human chorionic somatomammotropin (hCS) is encoded by two highly related genes, hCS-A and hCS-B, located in the hGH/hCS gene locus. Both genes are expressed in the syncytiotrophoblast layer of the ... [more ▼]

Human chorionic somatomammotropin (hCS) is encoded by two highly related genes, hCS-A and hCS-B, located in the hGH/hCS gene locus. Both genes are expressed in the syncytiotrophoblast layer of the placenta and hCS release from trophoblast cells is known to be increased by cAMP and phorbol esters. However, it remains unclear whether this regulation acts at the level of hCS gene expression or secretion and whether both genes are affected. We examined the effects of cAMP and phorbol 12-myristate 13-acetate (PMA) on the transcription of the hCS-A and hCS-B genes. Transient expression experiments revealed a 7 bp cAMP- and PMA-responsive element (CRElhCS-A) spanning nucleotides-1102 to -1096 upstream of the hCS-A gene. In contrast, the homologous sequence upstream of hCS-B (CRElhCS-B), differing from CRElhCS-A by a single substitution, shows little or no response to cAMP. In band-shift assays, the CRElhCS-A oligonucleotide was shown to bind two factors related to CREBP and AP-1, whereas CRElhCS-B only competes for one of these complexes. Finally, Southwestern analysis revealed that the CRElhCS-A element binds two ubiquitous proteins of 100 kDa and 47 kDa respectively, whereas CRElhCS-B interacts only with the 47 kDa protein. Taken together, these results suggest that a 47 kDa protein binding to the CRElhCS-A and CRElhCS-B elements is involved in the PMA response of the hCS-A and hCS-B genes, and a 100 kDa protein plays a crucial role in cAMP regulation of the hCS-A gene. [less ▲]

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See detailDietary fibre in dogs diet : comparisons between cellulose, pectin, guar gum, and between two incorporation rates of guar gum
Diez, Marianne ULg; Van Eenaeme, Christian ULg; Hornick, Jean-Luc ULg et al

in Journal of Animal Physiology & Animal Nutrition (1997), 78

Ausgewachsene Beagle-Hunde erhielten eine Kontrolldiaet (I) aus Hackfleisch und Reis oder mit Cellulose (II), Pektin (III) bzw. Guar (IV) angereicherte Diaeten mit einem Anteil von 3.4% in der ... [more ▼]

Ausgewachsene Beagle-Hunde erhielten eine Kontrolldiaet (I) aus Hackfleisch und Reis oder mit Cellulose (II), Pektin (III) bzw. Guar (IV) angereicherte Diaeten mit einem Anteil von 3.4% in der Trockenmasse. Bei Diaet IV tendierte die Magenentleerungsrate zu niedrigeren Werten. Die intestinale Absorption von Xylose wurde durch die Diaeten IV und III nicht beeinflusst, aber durch Diaet II sign. verlangsamt. Die Varianten III und IV fuehrten zu geringeren Trockenmassegehalten im Kot(p less than 0.001). Die zugefuehrten Faserstoffe senkten teilweise die Naehrstoffverdaulichkeit. Die preprandialen Plasmakonzentrationen an Glucose, Insulin, alpha-Amino-N, Harnstoff und Triglyceriden blieben unbeeinflusst. Die Diaet IV bewirkte einen deutlichreduzierten postprandialen Anstieg von alpha-Amino-N (p less than 0.05) und Harnstoff (p less than 0.01) im Plasma sowie geringere Cholesteringehalte bei gefuetterten und nuechternen Tieren (p less than 0.05). Ein weiterer Versuch mit 3.5% bzw. 7% Guaranteil in der Diaet zeigte dosisabhaengige Effekte. [less ▲]

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See detailEndoscopic laser treatment of uterine malformations.
Donnez, Jacques; NISOLLE, Michelle ULg

in Human Reproduction (1997), 12(7), 1381-7

Hysteroscopic resection of an intrauterine septum may benefit patients suffering from infertility or recurrent pregnancy loss. A partial or complete uterine septum can be easily resected using a Nd-YAG ... [more ▼]

Hysteroscopic resection of an intrauterine septum may benefit patients suffering from infertility or recurrent pregnancy loss. A partial or complete uterine septum can be easily resected using a Nd-YAG laser. If present, the vaginal septum may also be removed during the same procedure. The reproductive outcome of women treated by operative hysteroscopy for an intrauterine septum is reviewed. To avoid pregnancy in a non-communicating rudimentary horn, the removal of the horn and the homolateral tube may be performed by either bipolar coagulation or a CO2 laser. [less ▲]

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See detailThe Color Purple - les Blues Pourpres d'Alice Walker
Sacré, Robert ULg

in Les Cahiers du Jazz (1997), 12

Un livre (1982) - un film ( Steven Spielberg, 1985)

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See detail1897-1997 Les cent ans de la section des Eaux et Forêts
Rondeux, Jacques ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(4), 236-238

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See detailFibres alimentaires chez le chien V. Effets sur le métabolisme glucidique. Application dans le traitement du diabète
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141

Some dietary fibres are characterized by hypoglycaemic and hypoinsulinemic effects in humans and in carnivores. At present, these properties are used in the treatment of diabetes mellitus in both species ... [more ▼]

Some dietary fibres are characterized by hypoglycaemic and hypoinsulinemic effects in humans and in carnivores. At present, these properties are used in the treatment of diabetes mellitus in both species. Finally, the dietary treatment of the diabetic dog is presented with a particular emphasis on the use of dietary fibres. [less ▲]

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See detailMéthodes de stereologie et de morphometrie appliquées a l'etude des poumons
Jolly, S.; Gabriel, Annick ULg; Desmecht, Daniel ULg et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailDesodorisation des lisiers de porcs.
Thonart, Philippe ULg

in Agricontact (1997)

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See detailTotal cholesterol levels during adolescence: results of a Belgian MONICA population
Paulus, D.; Saint-Remy, Annie ULg; Rorive, Georges ULg et al

in Acta Cardiologica (1997), 52(2), 182-183

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See detailFibres alimentaires chez le chien VI. Effets sur le métabolisme lipidique, les sécrétions biliaires et application dans le traitement de l'obésité
Diez, Marianne ULg; Istasse, Louis ULg

in Annales de Médecine Vétérinaire (1997), 141(5), 363-372

Dietary fibres are able to affect lipids profiles in humans. The soluble and partly soluble fibres have mainly been studied in this purpose. Although hyperlipidaemia are known in dogs, there are few ... [more ▼]

Dietary fibres are able to affect lipids profiles in humans. The soluble and partly soluble fibres have mainly been studied in this purpose. Although hyperlipidaemia are known in dogs, there are few studies on the subject. The mechanisms by which fibres are involved are discussed with a particular emphasis on bile secretion. [less ▲]

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See detailEvaluation of some parameters influencing the drug delivery from a dry powder inhalation device using an in vitro model of the horse airways
Duvivier, Dominique Hannia; Chiap, Patrice ULg; Crommen, Jacques ULg et al

in Veterinary Research (1997), 28(6), 557-564

The aim of this study was to determine the effect of breathing pattern, air humidity and position of the device on the delivery of an aerosol generated by a dry powder inhalation (DPI) device (Inhalator M ... [more ▼]

The aim of this study was to determine the effect of breathing pattern, air humidity and position of the device on the delivery of an aerosol generated by a dry powder inhalation (DPI) device (Inhalator M). The in vitro inhalation study was performed using the cascade impaction method (Andersen Sampler) adapted to imitate nasal breathing. The amount of ipratropium found in the device, the artificial upper airways and the six stages of the Andersen Sampler was measured using high precision liquid chromatography. Stage 1 of the Andersen Sampler was considered to be the respirable fraction and stages 2 to 6 to be the non-respirable fraction. It was concluded that the theoretical respirable fraction of ipratropium obtained after DPI through Inhalator M was influenced by relative air humidity, air flow and the position of the device, whereas the number of successive inspirations and the duration of inspiration did not affect this fraction of the drug. [less ▲]

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See detailRoles of circadian rhythmicity and sleep in human glucose regulation.
Van Cauter, E.; Polonsky, K. S.; Scheen, André ULg

in Endocrine Reviews (1997), 18(5), 716-38

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See detailFunctional heterogeneity of human CD34(+) cells isolated in subcompartments of the G0 /G1 phase of the cell cycle.
GOTHOT, André ULg; Pyatt, R.; McMahel, J. et al

in Blood (1997), 90(11), 4384-93

Using simultaneous Hoechst 33342 (Hst) and Pyronin Y (PY) staining for determination of DNA and RNA content, respectively, human CD34(+) cells were isolated in subcompartments of the G0 /G1 phase of the ... [more ▼]

Using simultaneous Hoechst 33342 (Hst) and Pyronin Y (PY) staining for determination of DNA and RNA content, respectively, human CD34(+) cells were isolated in subcompartments of the G0 /G1 phase of the cell cycle by flow cytometric cell sorting. In both bone marrow (BM) and mobilized peripheral blood (MPB) CD34(+) cells, primitive long-term hematopoietic culture-initiating cell (LTHC-IC) activity was higher in CD34(+) cells isolated in G0 (G0CD34(+) cells) than in those residing in G1 (G1CD34(+) cells). However, as MPB CD34(+) cells displayed a more homogeneous cell-cycle status within the G0 /G1 phase and a relative absence of cells in late G1 , DNA/RNA fractionation was less effective in segregating LTHC-IC in MPB than in BM. BM CD34(+) cells belonging to four subcompartments of increasing RNA content within the G0 /G1 phase were evaluated in functional assays. The persistence of CD34 expression in suspension culture was inversely correlated with the initial RNA content of test cells. Multipotential progenitors were present in G0 or early G1 subcompartments, while lineage-restricted granulomonocytic progenitors were more abundant in late G1 . In vitro hematopoiesis was maintained for up to 6 weeks with G0CD34(+) cells, whereas production of clonogenic progenitors was more limited in cultures initiated with G1CD34(+) cells. To test the hypothesis that primitive LTHC-ICs would reenter a state of relative quiescence after in vitro division, BM CD34(+) cells proliferating in ex vivo cultures were identified from their quiescent counterparts by a relative loss of membrane intercalating dye PKH2, and were further fractionated with Hst and PY. The same functional hierarchy was documented within the PKH2(dim) population whereby LTHC-IC frequency was higher for CD34(+) cells reselected in G0 after in vitro division than for CD34(+) cells reisolated in G1 or in S/G2 + M. However, the highest LTHC-IC frequency was found in quiescent PKH2(bright) CD34(+) cells. Together, these results support the concept that cells with distinct hematopoietic capabilities follow different pathways during the G0 /G1 phase of the cell cycle both in vivo and during ex vivo culture. [less ▲]

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See detailSignes cliniques et diagnostic des tumeurs de la cavité nasale chez le chien: une analyse de 81 cas.
Clercx, Cécile ULg; Peeters, Dominique ULg; Gilbert, S. et al

in Annales de Médecine Vétérinaire (1997), 141

The paper describes clinical signs and diagnosis in 81 cases of intranasal tumors n the dog, examined at the Small Animal Clinic of the Faculty of Veterinary Medicine of the University of Liege (1990-1995 ... [more ▼]

The paper describes clinical signs and diagnosis in 81 cases of intranasal tumors n the dog, examined at the Small Animal Clinic of the Faculty of Veterinary Medicine of the University of Liege (1990-1995). Recent diagnostic techniques and therapeutic options are discussed. The most frequently encountered signs included a decreased or absence of unilateral air passage, observed in 78 cases (96%), and hemorrhagic discharge, observed in 65 cases (80%). Histopathology identified 2 benign and 79 malignant tumors, 57 epithelial and 22 mesenchymatous, including 2 lymphomas. In 74 cases, rhinoscopy identified an intranasal neoplastic mass; in the 7 remaining cases, tissular material of undetermined nature was observed, and histology of biospsied material confirmed the neoplastic nature. The time interval between the diagnosis and the death of the animal (spontaneous or by euthanasia) was longer in dogs with an intranasal sarcoma (mean time interval of 7 months) than in dogs with an intranasal carcinoma (mean time interval of 3 months). [less ▲]

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See detailGREES recommendations for the Registration of new drugs in the prevention and treatment of osteoporosis
Reginster, Jean-Yves ULg; Compston, J

in Calcified Tissue International (1997), 60

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See detailDynamique de défense du nid chez Symphodus ocellatus (Forsskål, 1775), poisson labridé méditerranéen. I. Comportements agonistiques entre le mâle territorial nidificateur et cinq autres espèces de labridés
Ylieff, Marc ULg; Michel, Christian ULg; Voss, Jacques

in Cahiers d'Ethologie (1997), 17(1), 49-74

This research in the field consists of a study of interspecific agonistic behaviour of territorial male in Symphodus ocellatus. This behaviour is useful for brood and nest defense. Four questions ... [more ▼]

This research in the field consists of a study of interspecific agonistic behaviour of territorial male in Symphodus ocellatus. This behaviour is useful for brood and nest defense. Four questions involving Symphodus ocellatus towards S. tinca, S. mediterraneus, S. roissali, Thalassoma pavo et Coris julis were investigated. The questions of interest were: (1) aggressors or intruders motivations (predation of the brood (a) and/or territorial conflicts (b)), (2) the recognition of this or that species (recognition studied with selective attacks by territorial male), (3) the organ(s) of perception used for this recognition and (4) the importance of territorial male investment in nest defense; this role could ensure a successful reproduction of the species. Our observations and experimentations (tested labrid fishes presented to T. males) allow us to affirm that in S. ocellatus, nesting territorial males recognize the various tested labrid fishes; that the organ of perception used for social recognition is the visual channel; that spawn protection insured by territorial male, a task guided by his visual system, is necessary towards menace of his congeners, but also the other fishes living in his habitat. Nevertheless, if it’s becoming clear that the Mediterranean labrid fishes have the ability to recognize and preferentially interact with particular individuals, the answer of the question 1, concerning aggressors motivations, is not yet clearly known. [less ▲]

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See detailUne chambre noire pour l’analyse textuelle
Tilkin, Françoise ULg; Mathonet, Anne

in Espace pour un humanisme européen (1997), 33

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See detailC.R. de M. MANCINI, Il punto su: I trovatori
Henrard, Nadine ULg

in Moyen Age (Le) (1997), CIII

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See detailSurveys of ultraviolet-excess quasar candidates in large fields
Gosset, Eric ULg; Moreau, O.; Surdej, Jean ULg et al

in Astronomy and Astrophysics. Supplement Series (1997), 123

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet ... [more ▼]

We describe the results of a survey for moderately bright quasars performed in a 20.6-square-degree field around the galaxy NGC 450. The quasar candidates were selected on the basis of their ultraviolet excess: by comparative visual inspection of the double image of each single object on a U/B dual-exposure Schmidt photographic plate, 95 primary and 45 secondary quasar candidates were selected on the basis of their $U$ image being too bright. The spectroscopic identification of the primary candidates led to the discovery of 59 bona fide quasars (out of which 6 were previously known). The Palomar Schmidt plate was digitised using the MAMA measuring machine and the outcoming data reduced using ad hoc procedures. A photometric calibration allowed us to derive values for the limiting magnitudes and for the U-B index selection threshold of the survey. A catalogue containing 60 quasars is presented with accurate positions, magnitudes and additional information such as redshifts. We studied the spatial distribution of the objects and detected, for the quasars of our sample, a significant deviation from randomness in the form of a propensity to cluster in pairs on the celestial sphere with a typical scale of about 10 arcmin. We also formally detected a tendency towards a 3-D clustering, but this result is induced by a single pair of quasars. A forthcoming paper will deal with a similar work performed in a field around NGC 520; the latter field is located directly to the North of the present one and slightly overlaps it. Based on observations acquired at the Mount Palomar and Las Campanas Observatories as well as at the European Southern Observatory. Also based on Schmidt-plate digitisations performed with the MAMA measuring machine of C.A.I. (I.N.S.U., Paris). [less ▲]

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See detailCompte rendu de Sénèque et la prose latine, (Entretiens sur l'Antiquité classique, 26), Fondation Hardt, 1991, 400 pp.
Longrée, Dominique ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (1997)

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See detailAnaesthesia for thoracoscopic surgery
Larbuisson, Robert ULg; Lamy, Maurice ULg

in Current Opinion in Anaesthesiology (1997), 10

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See detailA cinnabar local order in liquid II-VI compounds
Raty, Jean-Yves ULg; Gaspard, Jean-Pierre ULg; Ceolin, R. et al

in Physica B: Condensed Matter (1997)

A short wavelength (lambda=0.7 Aring) neutron scattering experiment has been performed on the II-VI compounds HgS, HgSe and Zn xHg 1-xTe. Liquid HgS can be viewed as a distortion of the blende structure ... [more ▼]

A short wavelength (lambda=0.7 Aring) neutron scattering experiment has been performed on the II-VI compounds HgS, HgSe and Zn xHg 1-xTe. Liquid HgS can be viewed as a distortion of the blende structure; we show that this distortion decreases gradually with temperature. For Zn xHg 1-xTe, we show that the transition between the six coordinated HgTe liquid and the four coordinated ZnTe liquid is not continuous, the intermediate phase being a deformed cinnabar one [less ▲]

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See detailDivergence of function and regulation of class B floral organ identity genes.
Samach, A.; Kohalmi, S. E.; Motte, Patrick ULg et al

in Plant Cell (1997), 9(4), 559-70

Regulatory mechanisms controlling basic aspects of floral morphogenesis seem to be highly conserved among plant species. The class B organ identity genes, which are required to establish the identity of ... [more ▼]

Regulatory mechanisms controlling basic aspects of floral morphogenesis seem to be highly conserved among plant species. The class B organ identity genes, which are required to establish the identity of organs in the second (petals) and third (stamens) floral whorls, are a good example of such conservation. This work compares the function of two similar class B genes in the same genetic background. The DEFICIENS (DEF) gene from Antirrhinum, including its promoter, was transformed into Arabidopsis and compared in function and expression with the Arabidopsis class B genes APETALA3 (AP3) and PISTILLATA (PI). The DEF gene was expressed in the second, third, and fourth whorls, as was PI. Functionally, DEF could replace AP3 in making petals and stamens. The DEF gene's AP3-like function and PI-like expression caused transformation of fourth-whorl carpels to stamens. Like AP3, all aspects of DEF function in Arabidopsis required a functional PI protein. Surprisingly, DEF could not replace the AP3 protein in properly maintaining AP3 transcripts (autoregulation). Our data allow us to revise the current model for class B autoregulation and propose a hypothesis for the evolution of class B gene expression in dicotyledonous plants. [less ▲]

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See detailLa violence dans les stades de football
Comeron, Manuel ULg

in Revue Générale (1997), (2), 21-30

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See detailStructural And Functional Properties Of The 154-171 Wild-Type And Variant Peptides Of Human Lecithin-Cholesterol Acyltransferase
Peelman, F.; Goethals, M.; Vanloo, B. et al

in European Journal of Biochemistry (1997), 249(3), 708-15

The 154-171 segment of the human lecithin-cholesterol acyltransferase (LCAT) enzyme was identified as the most stable amphipathic helix in the LCAT sequence. Its mean hydrophobicity, hydrophobic moment ... [more ▼]

The 154-171 segment of the human lecithin-cholesterol acyltransferase (LCAT) enzyme was identified as the most stable amphipathic helix in the LCAT sequence. Its mean hydrophobicity, hydrophobic moment and its orientation at a lipid/water interface are similar to those of some of the helical repeats of apolipoprotein A-IV and E. This domain was therefore proposed as a candidate peptide accounting for the association between LCAT and its lipid substrate. To investigate this hypothesis we synthesized the LCAT-(154-171)-peptide, two variants containing the natural Y156N and R158C mutations and a variant with increased hydrophobicity through Y156I, L160I, L163I and Y171W substitutions. The structural and lipid-binding properties of these synthetic peptides were investigated by turbidity, fluorescence, electron microscopy and circular dichroism. The wild-type peptide, the R158C variant in its dimeric form, as well as the more hydrophobic peptide, associated with phospholipids, whereas the Y156N and the R158C variant in its monomeric form did not. However, only the complexes generated with the hydrophobic variant were stable enough to resist dissociation during gel filtration. The wild-type peptide and hydrophobic variant formed discoidal complexes with dimyristoylglycerophosphocholine (Myr2GroPCho) as shown by negative staining electron microscopy. Comparison of the properties of the wild-type and hydrophobic variant LCAT-(154-171)-peptide stresses the contribution of the hydrophobic face of the amphipathic helix to the formation and stabilization of the peptide/lipid complexes. This is further confirmed by the decreased affinity of the Y156N variant peptide for lipids, as this mutation decreased the mean hydrophobicity of the hydrophobic face of the amphipathic helix. These results support the hypothesis that the 154-171 segment of LCAT might be involved in the interaction of the enzyme with its lipid substrate and suggest that the decreased activity of the Y156N natural LCAT mutant might result from a decreased affinity of this mutant for lipids. [less ▲]

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See detailMiospores from the type locality of the Middle Famennian Esneux Formation in the Ourthe Valley, eastern Belgium
Loboziak, S.; Avkhimovitch, V.I.; Streel, Maurice ULg

in Annales de la Société Géologique de Belgique (1997), 119(2), 111-118

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See detailImprovement of inland navigation in developping countries: the training center of Palembang (Sumatra, Indonesia), an example of transfer of technology through education
Marchal, Jean ULg

in Bulletin des Séances de l’Académie Royale des Sciences d’Outre-Mer = Mededelingen der Zittingen van de Koninklijke Academie voor Overzeese Wetenschappen (1997), Nouvelle Série 42(4)(1er trimestre), 10

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See detailFoaming properties of a natural cyclic lipoheptapeptide belonging to a special class of amphiphilic molecules
Razafindralambo, Hary ULg; Paquot, Michel ULg; Baniel, A. et al

in Food Hydrocolloids (1997), 11(1), 59-62

The foaming properties of surfactin, a natural cyclic lipoheptapeptide from Bacillus subtilis, were investigated in comparison and in association with those of bovine serum albumin (BSA). An apparatus ... [more ▼]

The foaming properties of surfactin, a natural cyclic lipoheptapeptide from Bacillus subtilis, were investigated in comparison and in association with those of bovine serum albumin (BSA). An apparatus combining bubbling, optical and conductimetric methods was used to study continuously foam formation and stability in terms of the quantity and density of foam. The increase in surfactin concentration from 0.05 to 0.2 mg/ml had little effect on its foaming capacity, measured by the bubbling time to produce the required foam volume, but improved the foam maximum density significantly. Surfactin produced foam with higher maximum density and stability, and forms more regular and smaller bubbles than BSA. In addition, a synergistic effect was observed on the stability of liquid in foam prepared with a mixture of 50:50 surfactin/BSA. The liquid half-life of BSA foam was enhanced up to 40% when surfactin was added to the solution. [less ▲]

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See detailReversibility of thiamine deficiency-induced partial necrosis and mitochondrial uncoupling by addition of thiamine to neuroblastoma cell suspensions.
Bettendorff, Lucien ULg; Goessens, Guy ULg; Sluse, Francis ULg

in Molecular and Cellular Biochemistry (1997), 174(1-2), 121-4

Culture of neuroblastoma cells in the presence of low thiamine concentration (16 nM) and of the transport inhibitor amprolium leads to the appearance of signs of necrosis: the chromatin condenses, the ... [more ▼]

Culture of neuroblastoma cells in the presence of low thiamine concentration (16 nM) and of the transport inhibitor amprolium leads to the appearance of signs of necrosis: the chromatin condenses, the oxygen consumption decreases and is uncoupled, the mitochondrial cristae are disorganized, the thiamine diphosphate-dependent dehydrogenase activities are impaired. When 10 microM thiamine are added to these cells, the basal respiration increases, the coupled respiration is restored and mitochondrial morphology is recovered within 1 h. Addition of succinate, which is oxidized via a thiamine diphosphate-independent dehydrogenase, to digitonin-permeabilized cells immediately restores a coupled respiration. Our results suggest that the slowing of the citric acid cycle is the cause of the biochemical lesion induced by severe thiamine deficiency and that part of the mitochondria remain functional. [less ▲]

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See detailUretero-arterial fistula: two observations.
VAN DAMME, Hendrik ULg; KEPPENNE, Véronique ULg; SakalihasanN, Natzi ULg et al

in Acta Chirurgica Belgica (1997), 97(3), 133-6

Two cases of life-threatening haematuria, secondary to an uretero-arterial fistula, are reported. Both cases present predisposing causative factors. One patient had a combination of previous aorto ... [more ▼]

Two cases of life-threatening haematuria, secondary to an uretero-arterial fistula, are reported. Both cases present predisposing causative factors. One patient had a combination of previous aorto-bifemoral bypass grafting, an iliac artery aneurysm (retrogradely perfused), and an indwelling ureteral stent for ureteral compression. The other patient had previous aortoiliac surgery and obstructive uropathy with chronic urinary tract infection. Preoperative diagnosis of uretero-arterial fistula was made in only one patient. He was successfully operated (exclusion of the iliac aneurysm). In the other patient, nephrectomy was attempted to control reno-ureteral bleeding of unknown origin. Fatal recidive of brisk haematuria occurred some days later. Factors contributing to the development of uretero-arterial fistula, their diagnosis and optimal treatment are discussed. [less ▲]

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See detailLe bois de tension. 1 Définition et distribution dans l'arbre.
Jourez, Benoît ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(2), 100-112

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See detailDetermination of radiative lifetimes of neutral sulphur by time-resolved three-photon VUV laser spectroscopy
Berzinsh, U.; Caiyan, L.; Zerne, R. et al

in Physical Review. A : General Physics (1997), 55

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See detailIn vivo behavior of poly(D,L)-lactide microspheres designed for chemoembolization
Flandroy, P.; Grandfils, Christian ULg; Danen, B. et al

in Journal of Controlled Release (1997), 44(2-3), 153-170

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is ... [more ▼]

Although chemoembolization advantageously combines arterial embolization of the vascular supply of a neoplasm with controlled intra-arterial infusion of chemotherapeutic drug(s), its application is limited by the lack of appropriate and reliable embolization materials. Recently, calibrated microspheres of poly(D,L)-lactide have proved to be promising in embolization. Nevertheless, repetitive chemoembolization requires the availability of microspheres degradable within a few days. For this purpose, microspheres consisting of a blend of two polyesters of a very different molecular weight (Mn =65 000 and 3500 in a 16:84 wt. ratio) have been prepared and injected in the renal arteries of rabbits. The in vivo fate of these two component microspheres has been compared by radiology and histology to microspheres prepared from the high molecular weight poly(D,L)-lactide. Furthermore, the in vivo degradation of the polymer has been measured by size exclusion chromatography after quantitative reextraction from the embolized kidney. Degradation kinetics has been compared to data previously reported in vitro. According to the observations performed during the in vivo study, the 50/50 microspheres appear more useful for the chemoembolization of tumors. [less ▲]

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See detailPlasma bovine pregnancy-associated glycoprotein concentrations throughout gestation in relationship fetal number in the cow
Patel, Osman V; Sulon, Joseph ULg; Beckers, Jean-François ULg et al

in European Journal of Endocrinology (1997), 137

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile ... [more ▼]

This study characterized the peripheral plasma bovine pregnancy-associated glycoprotein (bPAG) profile throughout gestation and examined the effect of stage of gestation and fetal number on this profile in Holstein cows after non-surgical embryo transfer. Cows (n = 12) were divided into three groups: group 1 = normal singleton pregnancies (n = 5); group 2 = normal twin pregnancies (n = 5); group 3 = abnormal twin pregnancies (n = 2). Blood was collected about every third day from day 0 (defined as the first day of standing estrus), then daily for the last 10 days of gestation, and sampling was stopped one day postpartum. The time-related changes in plasma bPAG concentrations were significantly (P < 0.01) affected by the stage of gestation and fetal number (P < 0.01), except during the last 10 days of gestation. In both normal pregnancy groups, bPAG concentration increased rapidly during the first trimester (0.5 +/- 0.1 to 14.6 +/- 1.7 ng/ml and 1.0 +/- 0.6 to 21.8 +/- 4.8 ng/ml, in singleton and twin-bearing groups respectively), then progressively between days 160 and 20 prepartum (31.6 +/- 6.2 to 114.3 +/- 31.3 ng/ml and 41.6 +/- 7.4 to 155.8 +/- 36.6 ng/ml in singleton and twin-bearing cows respectively). The mean concentration between days 20 and 10 prepartum approximately tripled (P < 0.001) in both these groups of cows (114.3 +/- 31.1 to 493.0 +/- 75.3 ng/ml and 155.8 +/- 36.6 to 409.3 +/- 114.7 ng/ml in singleton and twin-bearing cows respectively), but between days 10 prepartum and parturition the values increased about threefold (P < 0.01) in the singleton group (493.0 +/- 75.3 to 1352.8 +/- 286.5 ng/ml) and fivefold (P < 0.001) in the twin-bearing group (409.3 +/- 114.7 to 2154.0 +/- 505.7 ng/ml). The two cows in group 3 that gave birth prematurely to a stillborn calf or to a schistosomus reflexus calf exhibited an aberrant bPAG profile. Our results indicate that peripheral bPAG concentrations are correlated to the stage of gestation and fetal number, and that the profile of the peripheral plasma concentrations provides a useful indication of the feto-placental status. [less ▲]

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See detailFungal contamination in barley and Kashin-Beck disease in Tibet
Chasseur, Camille; Suetens, Carl; Nolard, Nicole et al

in Lancet (1997), 350

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See detailEnantioseparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using mixtures of anionic and uncharged beta-cyclodextrins as chiral additives.
Fillet, Marianne ULg; Hubert, Philippe ULg; Crommen, Jacques ULg

in Electrophoresis (1997), 18(6), 1013-8

Nine nonsteroidal anti-inflammatory drugs (NSAIDs) were enantioseparated by capillary electrophoresis using an anionic cyclodextrin derivative (sulfobutyl ether beta-cyclodextrin or carboxymethyl-beta ... [more ▼]

Nine nonsteroidal anti-inflammatory drugs (NSAIDs) were enantioseparated by capillary electrophoresis using an anionic cyclodextrin derivative (sulfobutyl ether beta-cyclodextrin or carboxymethyl-beta-cyclodextrin) in combination with a neutral cyclodextrin as chiral additives to a pH 3 phosphoric acid-triethanolamine buffer. In the presence of a negatively charged cyclodextrin, the analytes were given an appropriate mobility but relatively low enantioselectivities were generally obtained when such a cyclodextrin was the only selector added to the buffer. The addition of an uncharged cyclodextrin, such as the native beta-cyclodextrin or one of its derivatives (dimethyl-, trimethyl- and hydroxypropyl-beta-cyclodextrin), to this kind of buffer containing an anionic cyclodextrin, was found to give rise to considerable improvement in chiral resolution for all compounds studied. Resolution and analysis time were optimized by varying the nature and concentration of the two cyclodextrins. The best compromise was usually achieved by the simultaneous addition of sulfobutyl ether beta-cyclodextrin and trimethyl-beta-cyclodextrin. Under optimum conditions, the enantiomers of all NSAIDs examined could be completely separated (most often with resolution values higher than 5) in short analysis times (generally lower than 15 min). [less ▲]

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See detailPEGASE, une méthodologie et un outil de simulation prévisionnelle pour la gestion de la qualité des eaux de surface
Smitz, Joseph ULg; Everbecq, Etienne ULg; Deliège, Jean-François ULg et al

in Tribune de l'Eau (La) (1997), 50/4(588), 73-82

PEGASE (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières développé à l’Aquapôle qui permet de calculer de façon déterministe et prévisionnelle ... [more ▼]

PEGASE (Planification Et Gestion de l’ASsainissement des Eaux) est un modèle intégré bassins hydrographiques/rivières développé à l’Aquapôle qui permet de calculer de façon déterministe et prévisionnelle la qualité des eaux des rivières en fonction des rejets et apports de pollution. PEGASE est un outil opérationnel permettant d’orienter les choix des opérateurs publics et privés en matière de gestion des eaux de surface à l’échelle des bassins versants [less ▲]

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See detailIntegrator forwarding : a new recursive nonlinear robust design
Sepulchre, Rodolphe ULg; Jankovic, M.; Kokotovic, Petar V.

in Automatica (1997), 33(5), 979-984

We consider the global stabilization of nonlinear systems in strict feedforward form. We show that these systems, while not feedback linearizable, can be (globally) transformed by feedback and ... [more ▼]

We consider the global stabilization of nonlinear systems in strict feedforward form. We show that these systems, while not feedback linearizable, can be (globally) transformed by feedback and diffeomorphism into a lower-triangular form. The transformation is explicit and recursive. We employ this transformation to design a globally stabilizing controller with optimality properties and an input-to-state stability property with respect to matched uncertainties. [less ▲]

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See detailMorphological alterations of blood platelets induced by Platelet Activating Factor (PAF) and partial inhibition by Ketoprofen in calves
Bastos da Silva, Miriam; Doizé, Cécile ULg; David, Jean-Louis ULg et al

in Veterinary Research (1997), 28(5 Sep-Oct), 489-502

The influence of platelet activating factor (PAF) was investigated in vivo on the ultrastructure of bovine platelets, and on the platelet count. The effect of an intravenous administration of ketoprofen ... [more ▼]

The influence of platelet activating factor (PAF) was investigated in vivo on the ultrastructure of bovine platelets, and on the platelet count. The effect of an intravenous administration of ketoprofen (a non-steroidal anti-inflammatory drug) pretreatment followed by PAF infusion was also observed in a group of six healthy male Friesian calves. PAF infusion alone caused a moderate thrombocytopenia, which peaked one minute post challenge and returned to levels not significantly different from control after 30 min. Electron microscopy revealed that after PAF infusion, platelets lost their lentiform shape and became irregular, with many pseudopods. Their microtubules became impossible to distinguish. The numbers of alpha granules and dense bodies were significantly decreased. Glycogen particles became rare or even disappeared. Giant platelets occasionally appeared. The Golgi apparatus was more often visible and the number of mitochondria was significantly increased. Ketoprofen pretreatment lowered PAF-induced thrombocytopenia and decrease in the number of dense bodies. Under these conditions, the Golgi apparatus was rarely visible and giant platelets were not observed. These results showed that the morphological ultrastructure of blood platelets in bovines were modified following PAF infusion and that ketoprofen pretreatment before PAF infusion provided partial protection, limiting the extent of the morphological alterations and maintaining a normal platelet count [less ▲]

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See detailLa Belgique: Diversité territoriale
Merenne-Schoumaker, Bernadette ULg; Van der Haegen, H.; Van Hecke, E.

in Bulletin du Crédit Communal (1997), (202), 144

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques ... [more ▼]

Présentation synthétique en 16 thèmes des résultats des recherches d'équipes universitaires de la KULeuven, l'UCL, l'ULB, la VUB et l'ULg. Tableau de la situation de la Belgique en 1991 et des dynamiques entre 1981 et 1991. 155 cartes en couleurs. [less ▲]

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See detailEffects of sphingosine and sphingosine analogues on the free radical production by stimulated neutrophils: ESR and chemiluminescence studies.
Mouithys-Mickalad, Ange ULg; Deby, Ginette ULg; Hoebeke, Maryse ULg et al

in Mediators of Inflammation (1997), 6(5-6), 327-33

Sphingolipids inhibit the activation of the neutrophil (PMN) NADPH oxidase by protein kinase C pathway. By electron spin resonance spectroscopy (ESR) and chemiluminescence (CL), we studied the effects of ... [more ▼]

Sphingolipids inhibit the activation of the neutrophil (PMN) NADPH oxidase by protein kinase C pathway. By electron spin resonance spectroscopy (ESR) and chemiluminescence (CL), we studied the effects of sphingosine (SPN) and ceramide analogues on phorbol 12-myristate 13-acetate (PMA, 5 x 10(-7)M) stimulated PMN (6 x 10(6) cells). By ESR with spin trapping (100 mM DMPO: 5,5-dimethyl-1-pyrroline-Noxide), we showed that SPN (5 to 8 x 10(-6)M), C(2)-ceramide (N-acetyl SPN) and C(6)-ceramide (N-hexanoyl SPN) at the final concentration of 2 x 10(-5) and 2 x 10(-4)M inhibit the production of free radicals by stimulated PMN. The ESR spectrum of stimulated PMN was that of DMPO-superoxide anion spin adduct. Inhibition by 5 x 10(-6)M SPN was equivalent to that of 30 U/ml SOD. SPN (5 to 8 x 10(-6)M) has no effect on in vitro systems generating superoxide anion (xanthine 50 mM/xanthine oxidase 110 mU/ml) or hydroxyl radical (Fenton reaction: 88 mM H(2)O(2), 0.01 mM Fe(2+) and 0.01 mM EDTA). SPN and N-acetyl SPN also inhibited the CL of PMA stimulated PMN in a dose dependent manner (from 2 x 10(-6) to 10(-5)M), but N-hexanoyl SPN was less active (from 2 x 10(-5) to 2 x 10(-4)M). These effects were compared with those of known PMN inhibitors, superoxide dismutase, catalase and azide. SPN was a better inhibitor compared with these agents. The complete inhibition by SPN of ESR signal and CL of stimulated PMN confirms that this compound or one of its metabolites act at the level of NADPH-oxidase, the key enzyme responsible for production of oxygen-derived free radicals. [less ▲]

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See detailDe l’acyclovir au valacyclovir: la biodisponibilité en plus de l’efficacité et de la tolérance
Rentier, Bernard ULg

in Virologics (1997), (Septembre), 10-11

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See detailQuantitative ultrasound techniques for the assessment of osteoporosis : Expert agreement on current status
Glüer, CC; Reginster, Jean-Yves ULg

in Journal of Bone and Mineral Research (1997), 12(8), 1280-1288

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See detailBovine herpesvirus type 4. In Lymphotropicherpesviruses: Epstein-Barr virus and Human herpesvirus 8
Thiry, Etienne ULg; Lomonte, P.; Vanderplasschen, Alain ULg et al

in International Agency for research on cancer (1997)

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See detailBiomechanical assessment of the transversalis fascia and rectus abdominis aponeurosis in inguinal herniation - Preliminary results
PANS, Alain ULg; Pierard, Gérald ULg; Albert, Adelin ULg et al

in Hernia : the Journal of Hernias & Abdominal Wall Surgery (1997), 1

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See detailBeam-laser measurements and relativistic Hartree-Fock calculations of the lifetimes of the 3d94p levels in Cu II
Pinnington, E. H.; Rieger, G.; Kernahan, J. A. et al

in Canadian Journal of Physics (1997), 75

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See detailEtude histologique de lésions subcliniques de la lèvre latérale du talus chez le cheval
Yousfi, S.; Gabriel, Annick ULg; Maroit, V. et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailFatal Massive Liver Steatosis. A Clinicopathological Case Report
de Leval, Laurence ULg; Lambermont, Bernard ULg; D'Orio, Vincenzo ULg et al

in Acta Gastro-Enterologica Belgica (1997), 60(2, Apr-Jun), 180-183

Hepatic fatty change is a common lesion. Two forms are recognized: micro- and macrovesicular steatosis, the former being much less frequent and more serious than the latter. The case of an alcoholic woman ... [more ▼]

Hepatic fatty change is a common lesion. Two forms are recognized: micro- and macrovesicular steatosis, the former being much less frequent and more serious than the latter. The case of an alcoholic woman under anticonvulsivant therapy and with medications for a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) who presented with rapidly progressive cholestasis and hepatocellular failure is reported. Massive macro- and micro-vesicular hepatic steatosis was diagnosed at autopsy. The authors review the clinico-pathological features associated with this condition, and causal factors possibly implicated in this case are discussed in regard with currently considered pathophysiological mechanisms. [less ▲]

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See detailCompte rendu de L.C. Youtie, P. Michigan 17. The Michigan Medical Codex (P. Mich. 758 = P. Mich. inv. 21), Atlanta, 1996 (American Studies in Papyrology, 35)
Marganne, Marie-Hélène ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1997), 72

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See detailPsychrophiles et thermophiles : un problème d’enzyme
Gerday, Charles ULg; Aittaleb, M.; Arpigny, J. L. et al

in Chimie Nouvelle (1997), 15

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See detailApprentissage implicite et temps de réaction sériel: Une perspective développementale
Meulemans, Thierry ULg; Van der Linden, Martial ULg; Perruchet, Pierre

in Neuropsychiatrie de l'Enfance et de l'Adolescence (1997), 45(7-8), 384-386

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See detailFeeding of the sparid fish Sarpa salpa in a seagrass ecosystem: Diet and carbon flux
Havelange, S.; Lepoint, Gilles ULg; Dauby, Patrick ULg et al

in Marine Ecology (1997), 18(4), 289-297

In Revellata Bay (Gulf of Calvi, Corsica, France), the sparid fish Sarpa salpa L. is the main macro-consumer of Posidonia oceanica (L.) DELILE leaf. Stomach contents were analysed and C-13/C-12 isotopic ... [more ▼]

In Revellata Bay (Gulf of Calvi, Corsica, France), the sparid fish Sarpa salpa L. is the main macro-consumer of Posidonia oceanica (L.) DELILE leaf. Stomach contents were analysed and C-13/C-12 isotopic ratios were measured in fish muscle and potential food sources (algae, P. oceanica leaf and its epiphytes) to determine their relative contribution to the fish diet. S. salpa has an age-related mixed diet: juveniles are plankton feeders, young, sub-adults and adults are herbivorous, and, the older the individuals, the higher the relative contribution of P. oceanica to the diet. Our results and former studies of carbon stocks and fluxes in the P. oceanica bed of Revellata Bay have enabled an estimation of the general impact of S. salpa grazing on infralittoral communities: the studied species consumes 24 g C.m-2.a(-1) from P. oceanica leaf, 4.8 from epiphytes and 13 from epilithic algae. The fish net production and biomass turnover in that zone have been estimated to be 1.2 g C.m(-2).a(-1) and 1.5 a(-1), respectively. [less ▲]

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See detailLe cas clinique du mois, A propos d'un cas de myelinolyse centropontique chez un éthylique chronique
Lebrun, F.; Lambermont, Bernard ULg; Ghuysen, Alexandre ULg et al

in Revue Médicale de Liège (1997), 52(1), 7-11

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See detailOptimizing the treatment of Paget’s disease of bone
Reginster, Jean-Yves ULg; Gennari, C; Hosking, DJ et al

in Revue du Rhumatisme (English ed.) (1997), 64(4), 207-209

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See detailUne étude du style de vie de jeunes dans l’Union Européenne. Qu’en conclure et quels enseignements en tirer?
Piéron, Maurice; Ledent, Maryse; Delfosse, Catherine et al

in Sport (1997), 159/160

La littérature internationale continue à rassembler des indices en nombre croissant montrant l'étroite relation entre l'état de santé et la condition physique. Toutefois, une évolution très nette se ... [more ▼]

La littérature internationale continue à rassembler des indices en nombre croissant montrant l'étroite relation entre l'état de santé et la condition physique. Toutefois, une évolution très nette se marque dans l'identification des déterminants importants. La condition physique apparaît comme un produit très transitoire qui se détériore à partir du moment où l'on cesse de l'entretenir. ... [less ▲]

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See detailPrimary radiation therapy or surgery combined or not to radiation therapy in the management of squamous cell carcinoma of the penis
Zouhair, Abderrahim; Ozsahin, Mahmut; Douglas, Pelham et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 39(2 (Supplément)), 295

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See detailA novel virus blinding assay using confocal microscopy: demonstration that the intracellular and extracellular vaccinia virions bind to different cellular receptors
Vanderplasschen, Alain ULg; Smith, G. L.

in Journal of Virology (1997), 71

Vaccinia virus (VV) produces two antigenically and structurally distinct infectious virions, intracellular mature virus (IMV) and extracellular enveloped virus (EEV), which bind to unidentified and ... [more ▼]

Vaccinia virus (VV) produces two antigenically and structurally distinct infectious virions, intracellular mature virus (IMV) and extracellular enveloped virus (EEV), which bind to unidentified and possibly different cellular receptors. Studies of VV binding have been hampered by having two infectious virions and by the rupture of the EEV outer membrane in the majority of EEV virions during purification. To overcome these problems, we have developed a novel approach to study VV binding that is based on confocal microscopy and does not require EEV purification. In this assay, individual virus particles adsorbed to the cell are simultaneously distinguished and quantified by double immunofluorescence labelling with antibody markers for EEV and IMV. By this method, we show unequivocally that IMV and EEV bind to different cellular receptors. Three independent observations allow this conclusion. First, the efficiencies with which IMV and EEV bind to different cell lines are unrelated; second, cell surface digestion with some enzymes affects IMV and EEV binding differently; and third, the binding of a monoclonal antibody to cells prevents IMV binding but not EEV binding. This technique may be widely applicable for studying the binding of different viruses. [less ▲]

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See detailBounds on the Soft Pomeron Intercept
Cudell, Jean-René ULg; Kang, Kyungsik; Kim, Sung Ku

in Physics Letters B (1997), 395

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See detailNon délivrance et infécondité: intérêts de l’étiproston et du dosage de la PAGI (pregnancy-associated glycoprotein I) au cours du postpartum chez la vache.
Zaiem, I.; Tainturier, D.; Ben Othmen, H. et al

in Revue de Médecine Vétérinaire (1997), 148(8-9), 725-732

Sixty Prim'holstein cows with retained placenta for more than 24 hours after parturition, were shared in three groups of 20 cows each. All cows were delivred manually 24 to 36 hours post partum and ... [more ▼]

Sixty Prim'holstein cows with retained placenta for more than 24 hours after parturition, were shared in three groups of 20 cows each. All cows were delivred manually 24 to 36 hours post partum and received local treatment with 1 g of oxytetracyclin. Cows in group 1 received two intra-muscular injections of 5 mg etiproston on day of manual delivery (D1) and 15 days after (D15). Cows on group II received only one etiproston administration (D1), and cows in group III remained untreated. Ratios of delayed uterine involution were respectively 20, 40 and 55 % in groupsI,II and III(I<0.05;II<0.005). PAGI concentrations were checked 15 days after parturition and were significantly higher in cows affected by delayed uterine involution (p < 0.05). V-IAF intervals were significantly (p < 0.05) different between groups I (58 days), II (102 days) and III(143 days). [less ▲]

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See detailA propos de quelques utilisations non conventionnelles de la metformine
SCHEEN, André ULg; PAQUOT, Nicolas ULg; LETIEXHE, Michel ULg et al

in Médecine et Hygiène (1997), 55

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See detailEngraissement du taurillon Blanc-Bleu belge
Minet, Vincent; Van Eenaeme, Christian ULg; Raskin, Pascale et al

in Agricontact (1997), 291

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See detailSurveillance des états hypertensifs sévères
Brichant, Jean-François ULg

in Percentile (1997), 2

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See detailUltrastructural nucleolar alterations induced by an ametantrone/polyr(A-U) complex.
Thiry, Marc ULg; Jamison, J. M.; Gilloteaux, J. et al

in Experimental Cell Research (1997), 236(1), 275-84

In the present study we examined the ultrastructural modifications as well as the precise distribution of DNA and RNA in RT4 cell nucleoli following a 3-h exposure to nontoxic or toxic doses of ... [more ▼]

In the present study we examined the ultrastructural modifications as well as the precise distribution of DNA and RNA in RT4 cell nucleoli following a 3-h exposure to nontoxic or toxic doses of ametantrone (AMT), poly(adenylate-uridylate) (polyr(A-U), or an AMT/polyr(A-U) combination. While distribution of nucleic acids within the various nucleolar components is not modified following all treatments, the nucleoli exhibit several ultrastructural changes: redistribution of the nucleolar components, decrease in the number of fibrillar centers, and increase in the size of the fibrillar centers. The relative frequencies of the test agents to induce the apparition of nucleoli of compact type are AMT/polyr(A-U) > AMT approximately polyr(A-U) > sham-treated, while the abilities of the test agents to induce the nucleolar segregation are AMT/polyr(A-U) approximately AMT > polyr(A-U) > sham-treated cells. These ultrastructural changes are characteristics of drugs that intercalate into DNA and inhibit rDNA transcription as well as rRNA processing and release of nascent preribosomes from the nucleolus. [less ▲]

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See detailActivation of the transcription factor NF-kappaB in lipopolysaccharide-stimulated U937 cells
Legrand-Poels, Sylvie ULg; Maniglia, Salvator; Boelaert, J. R. et al

in Biochemical Pharmacology (1997)

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See detailThe state of stress near the Mendocino triple Junction from inversion of earthquake focal mechanism
Schwartz, S. Y.; Hubert, Aurelia ULg

in Geophysical Research Letters (1997), 23

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See detailFast and slow tracks in lysozyme folding: Insight into the role of domains in the folding process
Matagne, André ULg; Radford, S. E.; Dobson, C. M.

in Journal of Molecular Biology (1997), 267(5), 1068-1074

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of ... [more ▼]

The folding of lysozyme involves parallel events in which hydrogen exchange kinetics indicate the development of persistent structure at very different rates. We have monitored directly the kinetics of formation of the native molecule by the binding of a fluorescently labelled inhibitor, MeU-diNAG (4-methylumbelliferyl-N,N'-diacetyl-beta-D-chitobioside). The data show that native character monitored in this way also develops with different timescales. Although the rate determining step on the slow pathway (similar to 75% of molecules at pH 5.5, 20 degrees C) can be attributed to the need to reorganise structure formed early in the folding process, the data indicate that the rate determining step on the fast track (involving similar to 25% of molecules) involves the docking of the two constituent domains of the protein. In the fast folding track the data are consistent with a model in which each domain forms persistent structure prier to their docking in a locally cooperative manner on a timescale comparable to the folding of small single domain proteins. (C) 1997 Academic Press Limited. [less ▲]

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See detailTrajectoire déviante à la lisière entre adolescence et âge adulte
Gavray, Claire ULg

in Déviance et Société (1997), 21(3), 273-288

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See detailComparison of results of carotid artery surgery after either direct closure or use of a vein patch.
Desiron, Quentin ULg; Detry, Olivier ULg; Van Damme, Hendrik ULg et al

in Cardiovascular Surgery (1997), 5(3), 295-303

In order to assess the benefit of vein patching versus direct closure after carotid endarterectomy, a series of 2271 carotid operations were analysed retrospectively. Apart from 114 procedures consisting ... [more ▼]

In order to assess the benefit of vein patching versus direct closure after carotid endarterectomy, a series of 2271 carotid operations were analysed retrospectively. Apart from 114 procedures consisting of saphenous vein bypass (n = 29) and eversion endarterectomy (n = 85), 2157 open endarterectomies were performed. They were closed either directly (n = 837) or using a vein patch (n = 1320). The combined mortality-major neurological morbidity rate was 1.7%, i.e. 1% mortality (0.2% neurological) and 0.7% permanent neurological morbidity (0.5% ipsilateral to the operated artery). Early symptomatic internal carotid thrombosis was documented in six cases (four following direct closure and two after vein patching). A total of 827 carotid arteries were followed up by duplex scanning on an annual basis (244 direct closure and 583 vein patching). The mean follow-up was 44 months; 69 months for direct closure and 35 months for vein patching. In direct closure, there were 21 stenoses (9%) and 10 occult thromboses (4%); in vein patching carotids, there were 17 stenoses (3%), nine thromboses (1.8%) [corrected] and six pseudoaneurysms (1%). Annual incidence of poor results was 2.4% in direct closure, and 0.87% in vein patching. The only other factor responsible for a significant difference was gender (3.4% in women versus 2.1% in men). In this retrospective study, vein patching appears to be beneficial for the prevention of acute postoperative thrombosis and late stenosis or thrombosis. [less ▲]

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See detailPhylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae.
Elmoualij, Benaïssa ULg; Duyckaerts, Claire ULg; Brasseur, Josette ULg et al

in Yeast (Chichester, England) (1997), 13(6), 573-581

The screening of the open reading frames identified in the whole yeast genome has allowed us to discover 34 proteins belonging to the mitochondrial carrier family. By phylogenetic study, they can be ... [more ▼]

The screening of the open reading frames identified in the whole yeast genome has allowed us to discover 34 proteins belonging to the mitochondrial carrier family. By phylogenetic study, they can be divided into 27 subfamilies including ADP/ATP, phosphate and citrate carriers, putative oxoglutarate and GDC carriers and 22 new subfamilies. Topology predictions using the 'positive inside rule' approach have shown that the yeast carriers are similarly oriented with both extremities exposed to the cytosol. In each subfamily, a strict conservation of the charged residues in the six transmembrane alpha-helices is observed, suggesting a functional role for these residues and the existence of 27 functionally distinct carriers. [less ▲]

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See detailThe lowest 5g-6h supermultiplet of Fe II
Biémont, Emile ULg; Johansson, S.; Palmeri, P.

in Physica Scripta (1997), 55

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See detailThe 118-135 Peptide Lot The Human Prion Protein Forms Amyloid Fibrils And Induces Liposome Fusion
Pillot, T.; Lins, Laurence ULg; Goethals, M. et al

in Journal of Molecular Biology (1997), 274(3), 381-93

The prion protein (PrPC) is a glycoprotein of unknown function normally found at the surface of neurons and of glial cells. It is involved in diseases such as bovine spongiform encephalopathy, and ... [more ▼]

The prion protein (PrPC) is a glycoprotein of unknown function normally found at the surface of neurons and of glial cells. It is involved in diseases such as bovine spongiform encephalopathy, and Creutzfeldt-Jakob disease in the human, where PrPC is converted into an altered form (termed PrPSc). PrPSc is highly resistant towards proteolytic degradation and accumulates in the central nervous system of affected individuals. By analogy with the pathological events occuring during the development of Alzheimer's disease, controverses still exist regarding the relationship between amyloidogenesis, prion aggregation and neuronal loss. To unravel the mechanism of PrP neurotoxicity and understand the interaction of PrP with cellular membranes, a series of natural and variant peptides spanning residues 118 to 135 of PrP was synthesized. The potential of these peptides to induce fusion of unilamellar lipid vesicles was investigated. According to computer modeling calculations, the 120 to 133 domain of PrP is predicted to be a tilted lipid-associating peptide, and to insert in a oblique way into a lipid bilayer through its N-terminal end. In addition to amyloidogenic properties exhibited in vitro by these peptides, peptide-induced vesicle fusion was demonstrated by several techniques, including lipid- and core-mixing assays. Elongation of the 120 to 133 peptide towards the N- and C-terminal ends of the PrP sequence showed that the 118 to 135 PrP peptide has maximal fusogenic properties, while the variant peptides had no effect. Due to their high hydrophobicity, all peptides tested were able to interact with liposomes to induce leakage of encapsulated calcein. We demonstrate also that the propensity of the peptides to fold as an alpha-helix increases their fusogenic activity, thus accounting for the maximal fusogenic activity of the most stable helix at residues 118 to 135. These data suggest that, by analogy with the C-terminal domain of the beta-amyloid peptide, the fusogenic properties exhibited by the prion peptides might contribute to the neurotoxicity of these peptides by destabilizing cellular membranes. [less ▲]

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See detailInformation transfer between angiographic films and CT images: a tool to delineate the target volume
Tercier, P-A; COUCKE, Philippe ULg; Fankhauser, H et al

in Radiotherapy & Oncology (1997), 45

Abstract Background and purpose: This work was undertaken to improve the definition of target volumes for radiosurgery using the angiographic and CT data. Materials and methods: The basis of this new ... [more ▼]

Abstract Background and purpose: This work was undertaken to improve the definition of target volumes for radiosurgery using the angiographic and CT data. Materials and methods: The basis of this new method is to combine both imaging modalities and to compare them in each representation, i.e. to plot the volume obtained by angiography on CT images and also the contours defined by the CT on angiographic films. To obtain the angiographic volume, the radiographs are taken at several incidence angles. The X-ray sources position and the position of the films are determined using rectangular markers, then the intersection of all the loci of the target volume are calculated. Results: Verifications with a phantom show the accuracy of the procedure and the benefit obtained by increasing the number of angles of incidence in the angiographic imaging. The centre of gravity of the experimental target could be localized to an accuracy of better than 0.4 mm. The method was used in 11 clinical cases with excellent clinical results. Conclusions: The method can be easily applied and improves the delineation of target volumes in radiosurgery. CT data counterbalances the relative weakness of angiography concerning the three-dimensional geometry. Angiography adds useful information on the blood flow that is not shown in CT. Almost all the presented clinical cases benefit from the technique described here. [less ▲]

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See detailDevelopment of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression : Synthesis and in vitro evaluation of 9-{3-[18F] Fluoro-1-hydroxy-2-propoxymethyl guanine
Monclus, Michel; Luxen, André ULg; Cool, Vincent et al

in Bioorganic and Medicinal Chemistry Letters (1997), 7(14), 1879-1882

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission ... [more ▼]

9-[(3-fluoro-1-hydroxy-2-propoxy)methyl]guanine (FHPG) 2 has been labeled with fluorine-18 and evaluated in vitro as a potential radiotracer for mapping gene expression in vivo with positron emission tomography (PET). [less ▲]

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See detailMise au point d'une technique de culture in vitro d'embryons immatures de Phaseolus.
Mergeai, Guy ULg; Schmit, V.; Baudoin, Jean-Pierre ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (1997), 1(1),

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See detailCompte rendu de L.I. Conrad - M. Neve - V. Nutton - R. Porter - A. Wear, The Western Medical Tradition: 800 BC to AD 1800, Cambridge, 1995
Marganne, Marie-Hélène ULg

in Archives Internationales d'Histoire des Sciences (1997), 47(139 bis), 153-154

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