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See detailComparative Effects Of Deltamethrin And Neem Kernel Solution Treatments On Diamondback Moth And Cotesia Plutellae (Hym., Braconidae) Parasitoid Populations In The Cotonou Peri-Urban Area In Benin
Goudegnon, Ae.; Kirk, Aa.; Schiffers, Bruno ULg et al

in Journal of Applied Entomology-Zeitschrift Fur Angewandte Entomologie (2000), 124(3-4), 141-144

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See detailAquatic bryophyte assemblages along a gradient of regulation in the river Rhine
Vanderpoorten, Alain ULg; Klein, J. P.

in Hydrobiologia (2000), 410

A study of the zonation of the aquatic bryophyte assemblages from the Anterior Rhine to the Middle Rhine is presented. The typology obtained differs from the hydrogeoinorphological classification because ... [more ▼]

A study of the zonation of the aquatic bryophyte assemblages from the Anterior Rhine to the Middle Rhine is presented. The typology obtained differs from the hydrogeoinorphological classification because the correction of the river has led to the homogenization of habitats. Since the straightening of the river in the course of the 19th century, the embankments have created more stable habitats on which mountain species formerly characteristic of the rapids of the High Rhine appeared. During the 20th century, regulation, the construction of hydroelectric powerstations even the canalization of the river in Alsace. have caused a great change in water level. On the Upper Rhine, the rcgularisation of the water level .'allowed the appearance and the spread of strict hydrophytes such as Octodiceras fontanum which is now common between Rastatt and Bonn. Conversely, species characteristic of variable water levels decreased or disappeared. The industrial development along the river has caused water quality to severely decrease downstream of the industrial areas, hence the decrease or the disappearance of their primary flora in favour of pollution-tolerant assemblages. The former side channels of the Upper Rhine in France that have been disconnected from the main river and fed by groundwater since canalization, possess a bryophyte flora very similar to that of good quality waters in the upstream part of the High Rhine or in the Alpine Rhine. This flora is the last regional relic of a flora that has disappeared from the main channel due to water pollution. These refugia should consequently be preserved from the flooding of alluvial forests, part of the flood management program. [less ▲]

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See detailL’internationalisation des entreprises de distribution. Quelques observations au départ du cas européen
Merenne-Schoumaker, Bernadette ULg

in Géographies. Bulletin de l'Association de Géographes Français (2000), (2000-1), 66-73

To understand the internationalization of retailing, we must understand the internationalization of its entreprises. With this aim in view, one first case is chosen - Europa - and the processus is learned ... [more ▼]

To understand the internationalization of retailing, we must understand the internationalization of its entreprises. With this aim in view, one first case is chosen - Europa - and the processus is learned through the main questions of geography : what where ? which evolution ? who ? how ? why and why there and not elsewhere ? The lead of territory in the strategies and the choices of the firms is clearly showed; this fact confirms the geographical relevance of the thema « Globalization of Retailing ». [less ▲]

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See detailDes indicateurs européens de qualité de l'éducation : les langues étrangères : un premier exercice
Blondin, Christiane ULg; Demeuse, Marc ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), (3-4), 161-169

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See detailComparison between Open and Closed Repair for Abdominal Aortic Aneurysms: A Word of Caution
Limet, Raymond ULg; CREEMERS, Etienne ULg

in Acta Chirurgica Belgica (2000), 100(1), 12-5

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See detailLa maladie de Kashin-Beck et le milieu rural au Tibet: un problème agri-environnemental
Haubruge, Eric ULg; Chasseur, Camille; Mathieu, Françoise et al

in Cahiers Agricultures (2000), 9

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See detailLe financement public des cultes, de la laïcité et des cours philosophiques
Husson, Jean-François ULg

in Courrier Hebdomadaire du CRISP (2000), (1703-1704), 3-90

This publication details all channels through which religious and philosophical communities in Belgium are financed by local, regional or federal governments. Institutional environment is described ... [more ▼]

This publication details all channels through which religious and philosophical communities in Belgium are financed by local, regional or federal governments. Institutional environment is described. Detailed budgetary data are provided and are set in perspective with sociological data on religious practices or belonging. [less ▲]

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See detailSynthesis of an array antenna for hyperthermia applications
V Sabariego, Ruth ULg; Landesa, Luis; Obelleiro, Fernando

in IEEE Transactions on Magnetics (2000), 36(4), 1696-1699

In the present work the synthesis of an array antenna for hyperthermia treatment is developed. The selected antenna is an array antenna surrounded by a semicircular reflector which has shown to ease the ... [more ▼]

In the present work the synthesis of an array antenna for hyperthermia treatment is developed. The selected antenna is an array antenna surrounded by a semicircular reflector which has shown to ease the penetration and focalization in malignant biological tissues. A bolus is introduced as a protection in order to avoid an increasing heat hazard of superficial healthy tissues. The electric field within the biological medium will be modeled by means of the well known method of moments. The electromagnetic coupling problem is expressed in a closed form, enabling both a synthesis and an optimization procedure to be performed. Numerical results are included, illustrating the capabilities of the array antenna. [less ▲]

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See detailA new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi.
Bompard-Gilles, C; Villeret, V; Davies, G J et al

in Structure (2000), 8(2), 153-62

BACKGROUND: The L-aminopeptidase D-Ala-esterase/amidase from Ochrobactrum anthropi (DmpA) releases the N-terminal L and/or D-Ala residues from peptide substrates. This is the only known enzyme to liberate ... [more ▼]

BACKGROUND: The L-aminopeptidase D-Ala-esterase/amidase from Ochrobactrum anthropi (DmpA) releases the N-terminal L and/or D-Ala residues from peptide substrates. This is the only known enzyme to liberate N-terminal amino acids with both D and L stereospecificity. The DmpA active form is an alphabeta heterodimer, which results from a putative autocatalytic cleavage of an inactive precursor polypeptide. RESULTS: The crystal structure of the enzyme has been determined to 1.82 A resolution using the multiple isomorphous replacement method. The heterodimer folds into a single domain organised as an alphabetabetaalpha sandwich in which two mixed beta sheets are flanked on both sides by two alpha helices. CONCLUSIONS: DmpA shows no similarity to other known aminopeptidases in either fold or catalytic mechanism, and thus represents the first example of a novel family of aminopeptidases. The protein fold of DmpA does, however, show structural homology to members of the N-terminal nucleophile (Ntn) hydrolase superfamily. DmpA presents functionally equivalent residues in the catalytic centre when compared with other Ntn hydrolases, and is therefore likely to use the same catalytic mechanism. In spite of this homology, the direction and connectivity of the secondary structure elements differ significantly from the consensus Ntn hydrolase topology. The DmpA structure thus characterises a new subfamily, but supports the common catalytic mechanism for these enzymes suggesting an evolutionary relationship. [less ▲]

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See detailNanoindentation investigation of Ti/TiN multilayers films
Ben Daia, M.; Aubert, P.; Labdi, S. et al

in Journal of Applied Physics (2000), 87(11), 7753-7757

The hardness of Ti/TiN nanolaminated films is investigated in this study. Monolithic Ti and TiN films and Ti/TiN multilayers were deposited on silicon substrates by radio-frequency sputtering. The period ... [more ▼]

The hardness of Ti/TiN nanolaminated films is investigated in this study. Monolithic Ti and TiN films and Ti/TiN multilayers were deposited on silicon substrates by radio-frequency sputtering. The period thickness of multilayers was decreased from 20 to 2.5 nm. Grazing x-ray reflectometry showed that the modulation of composition of Ti/TiN multilayers exists for all the period thickness considered. From nanoindentation measurements, we determined the hardness and Young's modulus of multilayers. Hardness increased with decreasing period thickness to go beyond the rule-of-mixture value for samples with period thickness of Lambda less than or equal to 5 nm. The maximum hardness, 1.6 times higher than the value obtained by the rule of mixture, is obtained for Lambda=2.5 nm. Our results are compared to a dislocation-based model previously introduced by Lehoczky. (C) 2000 American Institute of Physics. [S0021-8979(00)09411-1]. [less ▲]

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See detailRadiation therapy alone or combined surgery and radiation therapy in squamous-cell carcinoma of the penis?
Zouhair, A; COUCKE, Philippe ULg; Jeanneret, W et al

in European Journal of Cancer (2000), 37(2), 198203

To assess the prognostic factors and the outcome in patients with squamous-cell carcinoma of the penis, a retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of the ... [more ▼]

To assess the prognostic factors and the outcome in patients with squamous-cell carcinoma of the penis, a retrospective review of 41 consecutive patients with non-metastatic invasive carcinoma of the penis, treated between 1962 and 1994, was performed. The median age was 59 years (range: 35–76 years). According to the International Union Against Cancer (UICC) 1997 classification, there were 12 (29%) T1, 24 (59%) T2, 4 (10%) T3 and 1 TX (2%) tumours. The N-classification was distributed as follows: 29 (71%) patients with N0, 8 (20%) with N1, 3 (7%) with N2 and 1 (2%) with N3. Forty-four per cent (n=18) of the patients underwent surgery: partial penectomy with (n=4) or without (n=12) lymph node dissection, or total penectomy with (n=1) or without (n=1) lymph node dissection. 23 patients were treated with radiation therapy alone, and all but 4 of the patients who were operated upon received postoperative radiation therapy (n=14). The median follow-up period was 70 months (range 20–331 months). In a median period of 12 months (range 5–139 months), 63% (n=26) of the patients relapsed (local in 18, locoregional in 2, regional in 3 and distant in 3). Local failure (stump in the operated patients, and the tumour bed in those treated with primary radiation therapy) was observed in 4 out of 16 (25%) patients treated with partial penectomy ±postoperative radiotherapy versus 14 out of 23 (61%) treated with primary radiotherapy (P=0.06). 15 (83%) out of 18 local failures were successfully salvaged with surgery. In all patients, 5- and 10-year survival rates were 57% (95% confidence interval (CI), 41–73%) and 38% (95% CI, 21–55%), respectively. The 5-year local and locoregional rates were 57% (95% CI, 41–73%) and 48% (95% CI, 32–64%), respectively. In patients treated with primary radiotherapy, 5- and 10-year probabilities of surviving with penis preservation were 36% (95% CI, 22–50%) and 18% (95% CI, 2–34%), respectively. In multivariate analyses, survival was significantly influenced by the N-classification, and surgery was the only independent factor predicting the locoregional control. We conclude that, in patients with squamous-cell carcinoma of the penis, local control is better in patients treated with surgery. However, there seems to be no difference in terms of survival between patients treated by surgery and those treated by primary radiotherapy ±salvage surgery, with 39% having organ preservation. [less ▲]

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See detailPercolation as a model for informetric distributions: fragment size distribution characterised by Bradford curves
Bogaert, Jan ULg; Rousseau, R; Van Hecke, P

in Scientometrics (2000), 47(2), 195-206

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See detailDependency of Premature Ventricular Contractions on Heart Rate and Circadian Rhythms During Childhood
Massin, M. M.; Maeyns, K.; Withofs, Nadia ULg et al

in Cardiology (2000), 93(1-2), 70-3

The aim of the present study was to identify and quantify the rate dependence of premature ventricular contractions (PVC) during childhood. A 24-hour Holter recording was performed in 16 consecutive ... [more ▼]

The aim of the present study was to identify and quantify the rate dependence of premature ventricular contractions (PVC) during childhood. A 24-hour Holter recording was performed in 16 consecutive children, aged 22 days to 11 years (mean age 5.6 years), with frequent (>5,000/day), isolated monomorphic PVC. Those PVC were identified and the length of the preceding sinus cycle was measured. The values were ordered into 50-ms class intervals, and the percentage of PVC for each class was calculated and then analyzed by linear regression analysis. On the basis of the significance of the p value, and the positive or negative value of the slope, we identified a tachycardia-enhanced, a bradycardia-enhanced, and an indifferent pattern. Chronobiologic analysis was made by the cosinor method. All the patients had upper and lower limits of cycle length beyond which PVC disappeared. A tachycardia-enhanced pattern was present in 7 patients and an indifferent one in 9 patients. In the latter a second-degree polynomial correlation was systematically found. Children but not infants had a significant circadian variation in the frequency of PVC with a very variable time of highest incidence. In conclusion, it is possible to identify a circadian rhythm of PVC and a spontaneous trend between their incidence and the length of the preceding cardiac cycle in children. [less ▲]

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See detailEffects of glucocorticoids on hepatic sensitivity to insulin and glucagon in man.
Dirlewanger, M.; Schneiter, P. H.; Paquot, Nicolas ULg et al

in Clinical Nutrition (2000), 19(1), 29-34

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one ... [more ▼]

AIMS: This study was undertaken to determine the effects of a short-term dexamethasone treatment on hepatic sensitivities to insulin and glucagon. METHODS: Eleven healthy subjects were studied during one or several of four protocols. In all protocols, somatostatin was infused continuously to inhibit pancreatic hormone secretion. In protocol 1, basal insulin was infused over 300 min while glucagon was infused at a rate of 0.5 mg/kg(-1)/min(-1)during 180 min, then at a rate of 1.5 ng/kg(-1)/min(-1)during 150 min. In protocol 2, the same experiment was performed after a 2 day treatment with 8 mg/day dexamethasone. In protocol 3, the two-step glucagon infusion was performed during insulin infusion at a rate aimed to reproduce the hyperinsulinemia observed during protocol 2. In protocol 4, continuous basal insulin and low glucagon (0.5 mg/kg(-1)/min(-1)) were infused over 330 min. RESULTS: In protocol 1, plasma glucose rose transiently by 2.0 +/- 0.3 mmol/l when the glucagon rate was increased and glucose production increased by 1.4 +/- 0.5 micromol/kg(-1)/min(-1). In protocol 2, the insulin infusion rate (1.85 +/- 0.36 nmol/kg(-1)/min(-1)) required to maintain glycemia was 3.3-fold higher than during protocol 1. Glucagon-induced stimulation of glycemia (by 1.47 +/- 0.5 mmol/l) and endogenous glucose production (by 0.8 +/- 0.3 micromol/kg(-1)/min(-1)) were blunted, but not abolished. In protocol 3, endogenous glucose production was suppressed by 75% by hyperinsulinemia and was not stimulated when the glucagon infusion rate was increased. In protocol 4, endogenous glucose production did not change significantly with time. CONCLUSION: These results indicate that high dose glucocorticoids induce a marked hepatic insulin resistance. Stimulation of glucose production by hyperglucagonemia was maintained in spite of hyperinsulinemia which can be attributed to either hepatic insulin resistance and/or increased hepatic glucagon sensitivity. [less ▲]

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See detailOuverture
Maes-Jelinek, Hena ULg

in Journal of Caribbean Literatures (2000), 2(1/2/3), 6-16

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See detailL'altération des bords de la tourbière active du Misten par l'exploitation de la tourbe pourrait dater du début du 14ième siècle
Hindryckx, Marie-Noëlle ULg; Streel, Maurice ULg

in Documents de la Station scientifique des Hautes-Fagnes (2000), 30(4), 95-101

Une étude récente (1999) de la végétation, de la variation du niveau de la nappe aquifère et des caractéristiques de la tourbe sous-jacente, à la périphérie de la tourbière active du Misten permet d ... [more ▼]

Une étude récente (1999) de la végétation, de la variation du niveau de la nappe aquifère et des caractéristiques de la tourbe sous-jacente, à la périphérie de la tourbière active du Misten permet d'entrevoir l'époque la plus probable d'exploitation de la tourbe dans la région de cette tourbière. Un calcul de la vitesse d'accumulation récente de la tourbe à différentes zones à la périphérie de la partie active de la tourbière a été effectué par des sondages de tourbe rapprochés et analysés finement au niveau palynologique. On constate que la vitesse d'accumulation de la tourbe varie selon les profils distants de 10m les uns des autres et que celle-ci diminue au fur et à mesure que l'on se rapproche du bord actuel de la tourbière active. A l'aide d'une datation au carbone 14, nous pouvons avancer que la date de l'altération du bord sud-est de la tourbière active du Misten a dû commencer vers 1330 AD (1170 + 160), soit bien antérieurement au creusement du fossé d'Eupen (1774), mais aussi bien avant les premières exploitations de tourbe connues dans les fagnes de Sourbrodt. [less ▲]

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See detailL'ouvrier, l'usine et le syndicalisme wallons. Involutions et enjeux (1960-2000). Le crépuscule des industrieux
Geerkens, Eric ULg

in Reflets et Perspectives de la Vie Economique (2000), (2-3), 254-255

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See detailCoumarinic derivatives as mechanism-based inhibitors of α-chymotrypsin and human leukocyte elastase
Pochet, Lionel; Doucet, Caroline; Dive, Georges ULg et al

in Bioorganic & Medicinal Chemistry (2000), 8(6), 1489-1501

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See detailAffections musculaires et intolrance à l'effort. 1- Pathogénie et approche diagnostique
Art, Tatiana ULg; Amory, Hélène ULg; Lekeux, Pierre ULg

in Pratique Vétérinaire Equine (2000), 32

The muscular condition, rhabdomyolysis, may cause exercise intolerance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical ... [more ▼]

The muscular condition, rhabdomyolysis, may cause exercise intolerance in the sporting horse. When the condition is recurring, it is often difficult for the equine practitioner to establish the clinical diagnosis (is the horse suffering from rhabdomyolysis or not ?) and the aetiology (what is/are the cause(s) of the condition ?) and also to provide an effective treatment [less ▲]

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See detailBase Plate in Bending and Anchor Bolts in Tension
Wald, Frantisek; Jaspart, Jean-Pierre ULg; sokol, Z et al

in Journal of Constructional Steel Research (2000)

The paper describes behaviour of the base plate in bending and the anchor bolts in tension, which is the major component of the base plate connection. The analytical model predicts the component ... [more ▼]

The paper describes behaviour of the base plate in bending and the anchor bolts in tension, which is the major component of the base plate connection. The analytical model predicts the component characteristics — the resistance and the stiffness. It is described how the quality of the behaviour is guided by the contact between the base plate and the concrete surface. The presented analytical prediction model is verified on tests and FE simulation. [less ▲]

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See detailComparison of a nurse-directed weight-based heparin nomogram with a standard doctor-based regimen
FRAIPONT, V; LAMBERMONT, Bernard ULg; MOONEN, M et al

in Intensive Care Medicine (2000), 26(4), 218

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See detailDe la relation spatiale entre les personnages des groupes statuaires royaux en Égypte pharaonique
Laboury, Dimitri ULg

in Revue d'Egyptologie (2000), 51

Given the unity of representational system of Ancient Egypt, the author proposes to investigate the possibility of application of the principle of the "rabattement" or folding back in a three-dimensional ... [more ▼]

Given the unity of representational system of Ancient Egypt, the author proposes to investigate the possibility of application of the principle of the "rabattement" or folding back in a three-dimensional art such as statuary, considering the case of the royal statue groups [less ▲]

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See detailEffet du couvert forestier sur la précison d'un système de positionnement global différentiel (dGPS)
Lejeune, Philippe ULg; Hellemans, Philippe

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(1), 41-49

Effect of forest canopy on the accuracy of a differential global positioning system (dGPS). The possibilities to use dGPS for forest mapping are analysed. The efficiency of dGPS in forest condition is ... [more ▼]

Effect of forest canopy on the accuracy of a differential global positioning system (dGPS). The possibilities to use dGPS for forest mapping are analysed. The efficiency of dGPS in forest condition is linked to canopy interference, which intercepts signals sent by some of the satellites or reflect them (multipathing). Two types of equipment have been tested : a TrimbleTM Svee Six coupled with a RDS differential receiver and a Trimble SK8 coupled with an OMNISTAR differential receiver. Recordings have been achieved according to two modes : static (recording on one spot during one minute) and cinematic (moving continuously along the stand limits). Two types of forest canopy were compared : light canopy made of young poplar plantation with few obstacles in the vicinity, and closed canopy of mature spruce stand edged with other mature stand. Cinematic mode efficiency is higher than static one (mean errors are respectively 3.1 m and 9.1 m). In the same way positioning is more accurate for the stand with light canopy than for the other one (mean errors are respectively 2.9 m and 9.4 m). Difference between recording modes are probably due to multipathing effect that filtering algorithm integrated in the GPS receivers are not able to remove in static mode. The efficiency of differential signal reception is also different for the two stands : 1.3 % and 20.5 % of missing differential signal respectively in the light and dense canopy conditions. [less ▲]

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See detailMultimedia education in headache: the European Neurological Network.
Russell, M. B.; Dremstrup Nielsen, K.; Rasmussen, C. et al

in European Journal of Neurology (2000), 7(3), 355-62

The European Neurological Network is a European Economic Community supported project. The purpose of the project was to develop a multimedia educational tool for general practitioners in order to improve ... [more ▼]

The European Neurological Network is a European Economic Community supported project. The purpose of the project was to develop a multimedia educational tool for general practitioners in order to improve their management of sleep disorders, epilepsy and headache. The project involves approximately one hundred engineers and physicians from Belgium, Denmark, England, Finland, France, Germany, Italy, Portugal and Spain. This paper concerns the multimedia educational tool on headache. The system consists of five different modules, i.e. classification, clinical data, headache tutorial, diagnostic headache diary and nomenclature. It is possible to move between the modules both vertically and horizontally. The headache classification of the International Headache Society is provided in full text as a work of reference. This classification is used world wide and has been adopted by International Classification of Diseases 10 Neurological Adaptation (ICD-10 NA) and the World Health Organisation. The clinical data concentrate on migraine and tension-type headache, the two most common headache disorders, but data on familial hemiplegic migraine, cluster headache, drug-induced headache and secondary headaches are also available. The headache tutorial consists of case records that the user can test their diagnostic abilities on. The diagnostic headache diary is an expert system on headache diagnostics. It can be filled in during a consultation in order to provide the headache diagnosis or it can be printed and used by the headache patient to record headache attacks and medicine consumption. The nomenclature module provides an explanation of words and expressions used in the system. [less ▲]

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See detailEffect of grade on disease-free survival and overall survival in FIGO Stage I adenocarcinoma of the endometrium.
Delaloye, J-F; Pampallona, S; COUCKE, Philippe ULg et al

in European Journal of Obstetrics & Gynecology & Reproductive Biology (2000), 88

Abstract Objective : To analyse the effect of differentiation on disease-free survival (DFS) and overall survival (OS) in patients with stage I adenocarcinoma of the endometrium. Patients and methods ... [more ▼]

Abstract Objective : To analyse the effect of differentiation on disease-free survival (DFS) and overall survival (OS) in patients with stage I adenocarcinoma of the endometrium. Patients and methods : From 1979 to 1995, 350 patients with FIGO stage IA–IC with well (G1), moderately (G2) or poorly (G3) differentiated tumors were treated with surgery and high dose-rate brachytherapy with or without external radiation. Median age was 65 years (39–86 years). Results : The 5-year DFS was 8863% for the G1 tumors, 7764% for the G2 tumors, and 6767% for the G3 tumors (P50.0049). With regard to the events contributing to DFS, the 5-year cumulative percentage of local relapse was 4.6% for the G1 tumors, 9.0% for the G2 tumors, and 4.6% (P50.027) for the G3 tumors. Cumulative percentage of metastasis was 1.4, 6.3 and 7.2% (P,0.001), respectively, whereas percentages of death were 6.0, 7.9 and 20.7% (P,0.001). The 5-year OS was 9163, 8364 and 7667%, respectively (P50.0018). In terms of multivariate hazard ratios (HR), the relative differences between the three differentiation groups correspond to an increase of 77% of the risk of occurrence of either of the three events considered for the DFS (HR51.77, 95% Cl [0.94–3.33]), (P50.078) for the G2 tumors and of 163% (HR52.63, 95% Cl [1.27–5.43]), (P50.009) for the G3 tumors with respect to the G1 tumors. The estimated relative hazards for OS are, respectively, in line with those for DFS: HR51.51 (P50.282) for the G2 tumors; and HR53.37 (P50.003) for the G3 tumors. Conclusion : Patients with grade 1 tumors are those least exposed to either local relapse, metastasis, or death. In contrast patients with grade 2 tumors seem to be at higher risk of metastasis, whereas patients with grade 3 tumors appear at higher risk of death. Since we have looked at the first of three competing events (local relapse, metastasis and death), this suggests that patients with grade 3 tumors probably progress to death so fast that local relapse, if any, cannot be observed. Ó 2000 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailEvidence of a reentrant Peierls distortion in liquid GeTe
Raty, Jean-Yves ULg; Godlevsky, V.; Ghosez, Philippe ULg et al

in Physical Review Letters (2000), 85(9), 1950-1953

The local atomic order of semiconducting liquid GeTe is studied using first-principles molecular-dynamics simulations. Our work points out a high degree of alternating chemical order in the liquid and ... [more ▼]

The local atomic order of semiconducting liquid GeTe is studied using first-principles molecular-dynamics simulations. Our work points out a high degree of alternating chemical order in the liquid and demonstrates the presence of a Peierls distortion close above the melting temperature. This distortion, absent in the high temperature crystalline structure of NaCl type, is a remnant of the atomic arrangement in the A7 low temperature crystalline phase. It disappears slowly with temperature, as the liquid evolves from a semiconducting to a metallic state. [less ▲]

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See detailInvolvement of acyl coenzyme A oxidase isozymes in biotransformation of methyl ricinoleate into γ-decalactone by Yarrowia lipolytica
Waché, Y.; Laroche, C.; Bergmark, K. et al

in Applied and Environmental Microbiology (2000), 66(3), 1233-1236

We reported previously on the function of acyl coenzyme A (acyl-CoA) oxidase isozymes in the yeast Yarrowia lipolytica by investigating strains disrupted in one or several acyl-CoA oxidase-encoding genes ... [more ▼]

We reported previously on the function of acyl coenzyme A (acyl-CoA) oxidase isozymes in the yeast Yarrowia lipolytica by investigating strains disrupted in one or several acyl-CoA oxidase-encoding genes (POX1 through POX5) (H. Wang et al., J. Bacteriol. 181:5140-5148, 1999). Here, these mutants were studied for lactone production. Monodisrupted strains produced similar levels of lactone as the wild-type strain (50 mg/liter) except for Δpox3, which produced 220 mg of γ-decalactone per liter after 24 h. The Δpox2 Δpox3 double-disrupted strain, although slightly affected in growth, produced about 150 mg of lactone per liter, indicating that Aox2p was not essential for the biotransformation. The Δpox2 Δpox3 Δpox5 triple- disrupted strain produced and consumed lactone very slowly. On the contrary, the Δpox2 Δpox3 Δpox4 Δpox5 multidisrupted strain did not grow or biotransform methyl ricinoleate into γ-decalactone, demonstrating that Aox4p is essential for the biotransformation. [less ▲]

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See detailLe maillage vert... ou les réseaux de toute nature...
Mougenot, Catherine ULg; Melin, Eric ULg

in Cahiers de l'Urbanisme (Les) (2000), (28-29), 42-45

Depuis quelques années se développent un peu partout des projets de sentiers nature, de réseaux de cheminements lents, de création de mares, de jardin au naturel, etc. Ils peuvent être regroupés sous le ... [more ▼]

Depuis quelques années se développent un peu partout des projets de sentiers nature, de réseaux de cheminements lents, de création de mares, de jardin au naturel, etc. Ils peuvent être regroupés sous le terme de maillage vert ou de réseau écologique. L'article souligne que pour que de tels projets aboutissent, ils supposent une interaction étroite entre réseaux naturels et réseaux humains. [less ▲]

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See detailNerve biopsy: indications and contribution to the diagnosis of peripheral neuropathy. The experience of the Born Bunge Foundation University of Antwerp and University of Liege between 1987 and 1997.
Deprez, Manuel ULg; Ceuterick-de Groote, C.; Schoenen, Jean ULg et al

in Acta Neurologica Belgica (2000), 100(3), 162-6

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined ... [more ▼]

We reviewed 355 nerve biopsies analysed at the Laboratories of Neuropathology of the Born-Bunge Foundation/University of Antwerp (BBF/UIA) and University of Liege (ULg) between 1987 and 1997. We examined the indications for nerve biopsy, the yield of the procedure, and the influence of clinical and neuropathological parameters. Contributory biopsies accounted for 35.5% and 47.3% respectively at ULg and BBF/UIA laboratories: of these, one third showed specific histological findings, the majority being informative only when combined with the relevant clinical data. The profile of indications for nerve biopsy was roughly comparable in both laboratories. The search for an inflammatory neuropathy prompted 35-40% of all biopsies with more than 50% of specimens being informative in this indication. The lowest yield (20%) was obtained among the nerve biopsies performed in the absence of any presumptive aetiology. These accounted for 22-33% of all cases. Inadequate surgical resection, delays in transport or processing errors precluded histological study of 4% (BBF/UIA) to 8% (ULg) of the specimens. We conclude that nerve biopsies should be performed by experienced surgeons and handled in specialised laboratories. Only a relatively small number of causes of neuropathy can be diagnosed on the basis of histology alone. More often, contributory biopsies will result from the combination of non-specific suggestive histological features with relevant clinical information. The diagnostic yield of nerve biopsy is function of careful patient selection and close collaboration between the clinician and the neuropathologist. [less ▲]

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See detailHet botkapitaal : een spaarboekje dat in de wieg begint
Halkin, V; Reginster, Jean-Yves ULg

in De Agenda Pediatrie (2000), 22

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See detailTheoretical Oscillator Strengths in Pr III and application to some CP stars
Palmeri, P.; Quinet, Pascal ULg; Frémat, Y. et al

in Astrophysical Journal Supplement Series (2000), 129

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See detailHabituation of visual and intensity dependence of auditory evoked cortical potentials tends to normalize just before and during the migraine attack.
Judit, A.; Sandor, P. S.; Schoenen, Jean ULg

in Cephalalgia : An International Journal of Headache (2000), 20(8), 714-9

Between attacks, migraine with (MO) or without aura (MA) patients show deficient habituation of pattern-reversal visual evoked potentials (PR-VEP) and a strong intensity dependence of auditory evoked ... [more ▼]

Between attacks, migraine with (MO) or without aura (MA) patients show deficient habituation of pattern-reversal visual evoked potentials (PR-VEP) and a strong intensity dependence of auditory evoked cortical potentials (IDAP). Clinical observations of migraine prodromes and previously published electrophysiological studies suggest that cortical information processing may vary in close temporal relationship to the attack. We studied PR-VEP and IDAP just before (11 MO pts), during (23 MO, 3 MA), 1 day following (27 MO, 1 MA) and 2 days following (14 MO) a migraine attack. The results were compared with a large group of MO patients recorded at a distance of at least 3 days from an attack (n = 66 for IDAP; n = 39 for VEP). Patients recorded the day before the attack had on average an habituation of -13.6+/-20.5% (mean +/- SD) between the 5th and 1st block of 100 averaged VEP responses and a flat (0.38+/-1.06 microV/10 dB) amplitude-stimulus intensity function (ASF) slope of the auditory evoked cortical potential. Both values were significantly different from those obtained in the attack interval (P=0.003; P=0.020). During the attack, VEP habituation was less pronounced (-0.17+/-26.2%) and ASF slopes remained flat (0.32+/-1.44 microV/10 dB; P=0.002 compared to interval). During the 2 days following the attack, VEP habituation was replaced by potentiation (+0.09+/-29.1% the 1st day; 19.5+/-45.7% the 2nd day) and ASF slopes increased markedly (0.87+/-1.39 and 1.14+/-1.12 microV/10 dB). The normalization of evoked cortical responses just before and during the attack, might reflect an increase in the cortical preactivation level due to enhanced activity in raphe-cortical serotonergic pathways. [less ▲]

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See detailIdentification de cultivars de palmier dattier (Phoenix dactylifera L.) par l'amplification aléatoire d'ADN (RAPD)
Ben Abdallah, Abdallah; Stiti, Kadija; Du Jardin, Patrick ULg et al

in Cahiers Agricultures (2000), 9(2), 103-107

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See detailNekrotoxikus Escherichia coli (NTEC) törzsek magyarorszagi elöfordulasa és jellemzése
Nagy, B.; Toth, I.; Mainil, Jacques ULg et al

in Magyar Allatorvosok Lapja = Hungarian Veterinary Journal (2000), 122

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See detailNote sous Bruxelles, 23 septembre 1999
Thirion, Nicolas ULg

in Droit des Affaires : Revue Internationale du Droit des Affaires = Ondernemingsrecht : Internationaal Tijdschrift voor Ondernemingsrecht [= DA OR] (2000), 55

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See detailL'osteoporose involutive de la femme: strategie therapeutique. Un point de vue actualise du Belgian Bone Club.
Kaufman, J M; Body, J J; Boonen, S et al

in Revue Médicale de Liège (2000), 55(5), 443-8

Osteoporosis is now considered as a major public health issue and a serious threat for the quality of life of elderly women. Several new compounds are currently marketed for the prevention and treatment ... [more ▼]

Osteoporosis is now considered as a major public health issue and a serious threat for the quality of life of elderly women. Several new compounds are currently marketed for the prevention and treatment of involutional osteoporosis in women. Therefore, it is important to offer to the practitioners pragmatic solutions to be used for the rational management of this disorder. This article is the result of a national consensus offering practical guidelines for the management of osteoporotic patients, based on the current published data. [less ▲]

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See detailMieux connaître la forêt privée. Appel aux propriétaires.
Rondeux, Jacques ULg; Bourland, Nils ULg

in Silva Belgica (2000), 107(1), 28-29

Dans le cadre de l'appui scientifique à l'Inventaire permanent des Ressources ligneuses de Wallonie, l'Unité de Gestion et Economie forestières (Prof. J. RONDEUX) de la Faculté universitaire des Sciences ... [more ▼]

Dans le cadre de l'appui scientifique à l'Inventaire permanent des Ressources ligneuses de Wallonie, l'Unité de Gestion et Economie forestières (Prof. J. RONDEUX) de la Faculté universitaire des Sciences agronomiques de Gembloux (FUSAGx) a été chargée de compléter l'information générale relative à la forêt privée, en particulier pour mieux identifier son degré de morcellement et l'évolution attendue de celui-ci dans un avenir proche. Ce travail est réalisé en étroite collaboration avec la Cellule Inventaire des Ressources ligneuses Wallonnes (Ir. H. LECOMTE) et bénéficie du soutien de la Société Royale Forestière de Belgique. [less ▲]

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See detailVariability of Doppler ultrasound measurements of hindlimb blood flow in conscious horses
Raisis, Anthea L; Young, L. E.; Meire, H. B. et al

in Equine Veterinary Journal (2000), 32(2), 125-132

Ultrasonography of the left and right femoral artery and vein was performed in 5 conscious horses. Velocity waveforms, recorded using low pulse repetition frequency, were used to calculate time-averaged ... [more ▼]

Ultrasonography of the left and right femoral artery and vein was performed in 5 conscious horses. Velocity waveforms, recorded using low pulse repetition frequency, were used to calculate time-averaged mean velocity (TAV), velocity of component a (TaVa), velocity of component b (TaVb) and volumetric flow. Waveform analysis included calculation of early diastolic deceleration slope (EDDS) and pulsatility index (PI) and subjective description of the waveform. Measurements were recorded at monthly intervals for 6 months. The repeated measurements were used to determine the within-horse variation. Horses were then anaesthetised with halothane and the same measurements recorded 60 min after induction. Differences between measurements recorded in conscious and anaesthetised horses were determined. Within-horse variability for diameters of femoral arteries and veins was small (CV<10%). Within variability for all other measurements was marked (CV>11%), with within-horse variability being the largest for femoral venous flow (CV>35%). Source of variability was measurement error and biological variation. Despite variability in conscious horses it was possible to detect changes in blood flow during anaesthesia. In the femoral arteries, volumetric flow was lower and EDDS and PI was higher in anaesthetised horses. In the femoral veins, volumetric flow was also lower in anaesthetised horses. Therefore Doppler ultrasound appears to be a useful technique for studying blood flow in conscious and anaesthetised horses [less ▲]

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See detailClinical Usefulness of the Mini Nutritional Assessment (Mna) Scale in Geriatric Medicine
Gazzotti, C.; Albert, Adelin ULg; Pepinster, A. et al

in Journal of Nutrition, Health & Aging (The) (2000), 4(3), 176-81

OBJECTIVE: This study was undertaken to estimate the prevalence of malnutrition in elderly patients hospitalized with an acute illness, as well as to assess the clinical usefulness of standardized ... [more ▼]

OBJECTIVE: This study was undertaken to estimate the prevalence of malnutrition in elderly patients hospitalized with an acute illness, as well as to assess the clinical usefulness of standardized nutritional assessment upon admission by means of the MNA scale. Design: A prospective study. Setting: A large size regional university hospital. Subjects: There were 175 patients (113 women and 62 men) with a mean age of 79.7 + 8.5 years admitted for an acute problem. Death occurred in 11 patients (6.3%). METHODS: Upon admission, demographic (age, gender, origin) and medical (disease, drugs) data were recorded for each patient; the MNA questionnaire (score: 0-30) was administered and Katz score (7-28) calculated. At hospital discharge, data included Katz score, outcome (death/survival), and destination. RESULTS: The mean MNA score was 20.5 + 5.1 and the prevalence of severe malnutrition (MNA <17) was 21.7%. Further, 48.6% of elderly were at risk of malnutrition (MNA between 17 and 24). There was no association between MNA and age or gender, but underweight was a sign of low MNA values (P <.001). MNA scores were inversely related to Katz scores at both admission and hospital discharge (P <.001). Patients originating from nursing homes had a poorer nutritional status than those living at home (MNA: 18.4 against 22.3, P <.001). The number of drugs taken per patient (5.2 + 2.8) was found to be correlated with MNA (P =.049). MNA scores were on average significantly higher (P <.001) in survivors (20.9) than in nonsurvivors (14.1). CONCLUSIONS: The study clearly demonstrates the high prevalence of malnutrition and the clinical usefulness of the MNA scale in geriatric medicine. The MNA score upon admission reflects the patient's nutritional condition, degree of autonomy (Katz score), living conditions and current treatment. It is also predictive of patient's outcome (death or survival). [less ▲]

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See detailDe l'archétype savant au stéréotype politique : figures médiatiques du leader ouvrier
Geuens, Geoffrey ULg

in Quaderni : la Revue de la Communication (2000), 40 ("Utopie I : la fabrique de l'utopie")(Hiver 1999-2000), 53-67

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See detailBeta-radiation for coronary in-stent restenosis
Latchem, D-R; Urban, P; Goy, JJ et al

in Catheterization and Cardiovascular Interventions (2000), 51(4), 422-429

To determine the feasibility and safety of an intracoronary beta-radiation device in preventing the recurrence of in-stent restenosis (ISR) after successful angioplasty, we studied 37 patients treated ... [more ▼]

To determine the feasibility and safety of an intracoronary beta-radiation device in preventing the recurrence of in-stent restenosis (ISR) after successful angioplasty, we studied 37 patients treated with beta-radiation (30-mm strontium-90 source) after angioplasty. The mean reference diameter was 2.9 ± 0.5 mm, and 62% of lesions were diffuse, including four total occlusions. Beta-radiation was successfully delivered in 36 of 37 (97%) cases. Over the course of 7.1 ± 4.5 mo follow-up, there were no myocardial infarctions and three deaths: one from preexisting malignancy, one from progressive cardiac failure, and one from sudden cardiac death. Target vessel revascularization (TVR) was performed in seven of 36 (19%) patients. Thirty patients underwent angiography at 6 mo; three (10%) experienced restenosis (diameter stenosis > 50%) at the target site, four (13%) had edge stenoses, and two (7%) had late (> 1 mo) thrombotic occlusions. Beta-radiation for ISR is associated with encouragingly low rates of target lesion restenosis and TVR. Further improvements are needed to solve the limitations of the edge effect and late occlusion. [less ▲]

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See detailLate Frasnian - Famennian climates based on palynomorph analyses and the question of the late Devonian glaciations.
Streel, Maurice ULg; Caputo, MV; Loboziak, S et al

in Earth-Science Reviews (2000), 52(1-3), 121-173

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See detailPredictive value of ovarian endometriosis?
NISOLLE, Michelle ULg; Donnez, Jacques

in Fertility and Sterility (2000), 73(2), 419-20

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See detailCharacterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase.
Liu, H.; Talmud, P. J.; Lins, Laurence ULg et al

in Biochemistry (2000), 39(31), 9201-12

The physicochemical properties of recombinant wild type and three site-directed mutants of apolipoprotein C-III (apoC-III), designed by molecular modeling to alter specific amino acid residues implicated ... [more ▼]

The physicochemical properties of recombinant wild type and three site-directed mutants of apolipoprotein C-III (apoC-III), designed by molecular modeling to alter specific amino acid residues implicated in lipid binding (L9T/T20L, F64A/W65A) or LPL inhibition (K21A), were compared. Relative lipid binding efficiencies to dimyristoylphosphatidylcholine (DMPC) were L9T/T20L > WT >K21A > F64A/W65A with an inverse correlation with size of the discoidal complexes formed. Physicochemical analysis (Trp fluorescence, circular dichroism, and GdnHCl denaturation) suggests that L9T/T20L forms tighter and more stable lipid complexes with phospholipids, while F64A/W65A associates less tightly. Lipid displacement properties were tested by gel-filtrating apoE:dipalmitoylphosphatidylcholine (DPPC) discoidal complexes mixed with the various apoC-III variants. All apoC-III proteins bound to the apoE:DPPC complexes; the amount of apoE displaced from the complex was dependent on the apoC-III lipid binding affinity. All apoC-III proteins inhibited LPL in the presence or absence of apoC-II, with F64A/W65A displaying the most inhibition, suggesting that apoC-III inhibition of LPL is independent of lipid binding and therefore of apoC-II displacement. Taken together. these data suggest that the hydrophobic residues F64 and W65 are crucial for the lipid binding properties of apoC-III and that redistribution of the N-terminal helix of apoC-III (L9T/T20L) enhances the stability of the lipid-bound protein, while LPL inhibition by apoC-III is likely to be due to protein:protein interactions. [less ▲]

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See detailConsequences of total and subtotal myeloperoxidase deficiency: risk or benefit ?
Kutter, D.; Devaquet, P.; Vanderstocken, G. et al

in Acta Haematologica (2000), 104(1), 10-5

A group of 100 totally or subtotally myeloperoxidase (MPO)-deficient individuals was compared to a reference population of 118 probands selected at random. Data for a protective effect of the deficiency ... [more ▼]

A group of 100 totally or subtotally myeloperoxidase (MPO)-deficient individuals was compared to a reference population of 118 probands selected at random. Data for a protective effect of the deficiency against cardiovascular damage are presented. On the other hand, a significantly higher occurrence of severe infections and chronic inflammatory processes was noted among the deficient patients. An increased incidence of cancer among the MPO-deficient individuals was not demonstrated. [less ▲]

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See detailCharacterization of intestinal cnf1+ Escherichia coli from weaned pigs
Toth, I.; Oswald, E.; Mainil, Jacques ULg et al

in International Journal of Medical Microbiology (2000), 290

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See detailBiotransformation of ricinoleic acid into g-decalactone by yeast cells: recent progress and current questions
Aguedo, Mario ULg; Waché, Yves; Belin, J.M.

in Recent Research Developments in Biotechnology & Bioengineering (2000), 3

Lactone aroma compounds production can be achieved biotechnologically by microbial fermentation and notably using yeasts. Many studies have been carried out to understand the mechanisms implicated in such ... [more ▼]

Lactone aroma compounds production can be achieved biotechnologically by microbial fermentation and notably using yeasts. Many studies have been carried out to understand the mechanisms implicated in such bioreactions, and a pathway involving peroxisomal β-oxidation was established but some unelucidated points remain. In the recent years, new developments appeared proposing biotechnological ways to overcome and understand lactone toxicity or its commonly observed reconsumption and trying to explain some confused points like fatty acid emulsification, entry and storage into the cell. The importance of acyl-CoA oxidases in the metabolic pathway implicated and thus in the lactone production as well as on its reconsumption was also focused. Simultaneously with a presentation of the biotransformation pathways, these points are discussed in the light of new data including not yet published data obtained mainly with the yeast Yarrowia lipolytica. [less ▲]

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See detailMeasurements of hindlimb blood flow recorded using Doppler ultrasound during administration of vasoactive agents in halothane-anesthetized horses
Raisis, Anthea L; Young, Lesley E; Meire, Hylton B et al

in Veterinary Radiology & Ultrasound : The Official Journal of the American College of Veterinary Radiology & the International Veterinary Radiology Association (2000), 41(1), 64-72

The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulation of arterial blood pressure. Doppler ultrasonography ... [more ▼]

The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulation of arterial blood pressure. Doppler ultrasonography was performed in the femoral vessels of six halothane-anesthetized horses before and during administration of phenylephrine HCI and sodium nitroprusside. The time-averaged mean velocity and volumetric flow were calculated. The contour of the velocity waveform was assessed, and the early diastolic deceleration slope (EDDS) and pulsatility index (PI) were calculated. Administration of phenylephrine HCI resulted in increased mean aortic blood pressure (MABP) by 40% (29.3-53.0%). This caused significant decrease in cardiac output (26.8 to 13.5 l/min), femoral arterial velocity (left artery 7.20 to 4.00 cm/s; right artery 5.01 to 3.39 cm/s) and volumetric flow (left artery 556 to 221 ml/min; right artery 397 to 193 ml/min) in the femoral vessels and significant increase in systemic vascular resistance (163 to 433 dyn-s/cm5), EDDS (1a: 285 to 468: ra: 250 to 481) and PI (1a: 9.38 to 20.4; ra 17.1 to 29.1). Administration of sodium nitroprusside resulted in a decreased MABP of 27.2% (22.5-33%). This increased cardiac output (20.8 to 32.4 L/min), however, no significant changes were observed in femoral blood flow. Despite obvious changes in the waveform contour, no significant change occurred in EDDS or PI. These results suggest that Doppler ultrasound may be useful for measuring femoral blood flow in anesthetized horses. However, waveform analysis appears to be limited when multiple changes occur in central and peripheral haemodynamics. [less ▲]

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See detailSocial Feeding In Ladybird Beetles: Adaptive Significance And Mechanism
Hemptinne, Jl.; Gaudin, M.; Dixon, Afg. et al

in Chemoecology (2000), 10(3), 149-152

Young larvae of Adalia bipunctata search an area more intensively when exposed to the odour from other larvae feeding on aphids than when exposed only to the odour of aphids. In an olfactometer young ... [more ▼]

Young larvae of Adalia bipunctata search an area more intensively when exposed to the odour from other larvae feeding on aphids than when exposed only to the odour of aphids. In an olfactometer young larvae were significantly attracted either to the odour of crushed aphids or larvae feeding on aphids, but not to that of aphids, larvae, larvae plus aphids or larvae feeding on an artificial diet. That is, the change in searching behaviour appears in response to a volatile released by aphids when attacked. The odour released by crushed aphids is made up entirely of aphid alarm pheromone, b-farnesene. It is likely that the adaptive significance of this response is that it increases the ability of larvae to locate larvae that have already caught prey. By sharing the aphid kill of another larva it is likely that a first instar ladybird larva greatly increases its probability of surviving to the next instar. It is suggested that this social feeding is facilitated by egg clustering, which also may additionally account for why aphidophagous ladybirds lay their eggs in clusters. [less ▲]

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See detailComment j'explore ... les anomalies du metabolisme glucidique, de l'insulinosecretion et de la sensibilite a l'insuline avec une hyperglycemie provoquee par voie orale.
Luyckx, Françoise ULg; Scheen, André ULg

in Revue Médicale de Liège (2000), 55(9), 881-5

Oral glucose tolerance test (OGTT) has been widely used for the diagnosis of diabetes mellitus, gestational diabetes, impaired glucose tolerance or reactive hypoglycaemia. Simultaneous measurements of ... [more ▼]

Oral glucose tolerance test (OGTT) has been widely used for the diagnosis of diabetes mellitus, gestational diabetes, impaired glucose tolerance or reactive hypoglycaemia. Simultaneous measurements of plasma glucose and insulin levels also allow to derive indices of insulin secretion and insulin sensitivity. Whereas OGTT is not considered anymore as the first choice for the diagnosis of diabetes mellitus, it remains useful for studying abnormalities of glucose metabolism as well as of insulin secretion and insulin action. [less ▲]

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See detailCellulite: from standing fat herniation to hypodermal stretch marks.
Pierard, Gérald ULg; NIZET, Jean-Luc ULg; PIERARD-FRANCHIMONT, Claudine ULg

in American Journal of Dermatopathology (2000), 22(1), 34-7

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens ... [more ▼]

There are glaring discrepancies in the microanatomical descriptions of cellulite in the literature. We revisited this common skin condition in women with a microscopic examination of 39 autopsy specimens. A control group consisted of 4 women and 11 men showing no evidence of cellulite. The lumpy aspect of the dermohypodermal interface appeared to represent a gender-linked characteristic of the thighs and buttocks without being a specific sign of cellulite. Incipient cellulite identified by the mattress phenomenon was related to the presence of focally enlarged fibrosclerotic strands partitioning the subcutis. Such strands possibly serve as a physiologic buttress against fat herniation limiting the outpouching of fat lobules on pinching the skin. These structures might represent a reactive process to sustained hypodermal pressure caused by fat accumulation. Full-blown cellulite likely represents subjugation of the hypertrophic response when connective tissue is overcome by progressive fat accumulation. Histologic aspects reminiscent of stretch marks are identified within the hypodermal strands, resulting in clinical skin dimpling. [less ▲]

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See detailResource Trading Agents for Adaptive Active Network Applications
Yamamoto, Lidia; Leduc, Guy ULg

in Networking and Information Systems Journal (2000), 3(4-5), 743-768

Adaptive applications seem to be the only realistic answer to the increasing diversity and decentralisation in networks. In order to accommodate fluctuations in network conditions, adaptive applications ... [more ▼]

Adaptive applications seem to be the only realistic answer to the increasing diversity and decentralisation in networks. In order to accommodate fluctuations in network conditions, adaptive applications need to obtain information about resource availability. Using mobile agent technology applied to active networks, new models for adaptive applications can be envisaged. In this article we review the state of the art in agent and active network techniques for adaptive applications, and describe our work on an agent model for trading resources inside an active network node. We apply the model to the case of an audio mixing application. Our simulation results indicate that the model allows the application to make efficient use of the available resources, and to share resources according to user preferences. [less ▲]

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See detailHigh-energy forward scattering and the pomeron: Simple pole versus unitarized models
Cudell, Jean-René ULg; Ezhela, V.; Kang, K. et al

in Physical Review. D : Particles and Fields (2000), 61

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See detailSome influences of sediments in aerated lagoons and waste stabilization ponds
Chabir, D.; El Ouarghi, H.; Brostaux, Yves ULg et al

in Water Science & Technology (2000), 42(10), 237-246

Respirometric tests have been undertaken on sediments in aerated lagoons and waste stabilization ponds to quantify their oxygen demand and to determine the main factors governing the process. Factors such ... [more ▼]

Respirometric tests have been undertaken on sediments in aerated lagoons and waste stabilization ponds to quantify their oxygen demand and to determine the main factors governing the process. Factors such as seasonal variations, temperature, substrate, sediment layer thickness, density of macro-invertebrates and suspended sediments were investigated. The results showed that temperature and substrate concentration are the main factors that influence sediment oxygen demand; followed by spatial heterogeneity and resuspension of sediments, whereas the density of macro-invertebrates could have an effect in summer (hot season). Sediment layer thickness had no effect. A model of sediment oxygen demand is developed for the two main factors (temperature and substrate) with an r2 of 0.98. [less ▲]

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See detailEntre stalle et prie-Dieu. La religieuse liégeoise en prière
Henneau, Marie-Elisabeth ULg

in Revue de l'Histoire des Religions (2000), 217(3), 327-344

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See detailLa trisomie 21 : étude d’une stratégie de mémorisation
Frenkel, Stéphanie ULg

in Le Journal des Psychologues (2000), 182

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See detailLégislation et exercice de l'entomologie en Région wallonne
Fagot, Jean ULg; Dethier, Michel ULg

in Notes Fauniques de Gembloux (2000), 41

In Wallonia, a new law is in study to set up a better level of protection for the fauna and the flora, and that, in respect of the european spirit of Nature preservation. On the other hand, a lot of ... [more ▼]

In Wallonia, a new law is in study to set up a better level of protection for the fauna and the flora, and that, in respect of the european spirit of Nature preservation. On the other hand, a lot of territories are raised to different level of protection. The authors enumerate the consequences of the new act and European directives on the practice of the entomology in Wallonia. [less ▲]

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See detailTubal versus uterine placentation: similar HLA-G expressing extravillous cytotrophoblast invasion but different maternal leukocyte recruitment
Proll, J.; Bensussan, A.; Goffin, Frédéric ULg et al

in Tissue Antigens (2000), 56(6), 479-491

The nonclassical HLA-G class I gene is expressed by extravillous cytotrophoblast that invades decidua in uterine pregnancy, suggesting that it may contribute to the immunological mechanisms that protect ... [more ▼]

The nonclassical HLA-G class I gene is expressed by extravillous cytotrophoblast that invades decidua in uterine pregnancy, suggesting that it may contribute to the immunological mechanisms that protect the fetus against maternal alloimmune response and/or pathogen infections. We first addressed the question of whether HLA-G expression was dependent on maternal tissue environment by comparing uterine and ectopic tubal pregnancies. Using HLA-G-specific mAb on placental cryosections, we found by immunohistochemistry that all subtypes of extravillous cytotrophoblast similarly expressed HLA-G in pregnant tubes, demonstrating that its expression was independent of the site of implantation. We next compared by immunohistochemistry the phenotype of maternal leukocytes recruited in both pregnant tissues. In contrast to decidua, pregnant tubes were characterized firstly, by the lack of natural killer (NK) cells and of cells expressing CD94 receptor specific for HLA-E, secondly, by a prominent increase of CD8+ T cells, dendritic cells, and macrophages, the latter co-expressing the LIR1/ILT2 killer immunoglobulin-like receptor (KIR), and finally, by the presence of cells expressing LIR2/ILT4 KIR or BY55 NK receptors, known to bind to HLA-G. Such cell types may favor a unique innate defense in pregnant tubes. These observations also suggest that trophoblast HLA-G expression does not influence the recruitment of particular maternal leukocytes in pregnant tissues. [less ▲]

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See detailImpact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.
Hustinx, Roland ULg; Dolin, R. J.; Benard, F. et al

in European Journal of Nuclear Medicine (2000), 27(9), 1365-71

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating ... [more ▼]

The aim of this study was to evaluate image quality and lesion detectability with and without attenuation correction in patients with abdominal tumors, using a free-response receiver operating characteristic (FROC) methodology. Thirty-four patients with various abdominal tumors were evaluated (11 men, 23 women, median age 48 years). Whole-body emission scans were performed 68 min (35-102 min) after intravenous injection of 4.3 MBq/kg fluorine-18 fluorodeoxyglucose (FDG). Images were reconstructed using the OS-EM algorithm and corrected for attenuation either using postinjection singles transmission (n=27) or by calculation and body outline (n=7). Total scan duration did not exceed 70 min. Studies were read independently by four observers unaware of any clinical data. The uncorrected (UC) images were systematically read before the attenuation-corrected (AC) images. All studies were given an image quality score ranging from 1 (unreadable) to 5 (excellent). Each focus of increased activity was then localized and given a probability of malignancy using a five-point scale. The average image quality score was similar for both UC and AC images. At the time of the positron emission tomography (PET) scans, 127 lesions (63 liver metastases, 9 retroperitoneal lesions, 50 peritoneal or bowel lesions, and 5 pancreatic carcinomas) were revealed by pathological or correlative studies. The areas under the FROC curves were consistently greater for AC images (range 0.8663-0.8867) than for UC images (range 0.7774 -0.8613). Overall, the difference between the AC images and the UC images was significant (P=0.019). In particular, correction for attenuation increased the sensitivity regardless of the location of the lesions. In conclusion, correction for attenuation significantly improves the diagnostic accuracy of FDG-PET for abdominal staging of neoplasms, without impairing the image quality. [less ▲]

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See detailParticularités de la prise en charge de l’excès pondéral chez l’adolescent : résultats d’une enquête exploratoire
Glowacz, Fabienne ULg; Bourguignon, J. P.; Born, Michel ULg

in Bulletin d’Education du Patient (2000), 19(3), 132-140

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See detailCas clinique pour la rubrique “ Imagerie médicale ”
Noels, C.; Busoni, Valeria ULg

in Pratique Vétérinaire Equine (2000)

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See detailIdentification and characterization of in vivo attenuated mutants of Brucella melitensis.
Lestrate, P.; Delrue, R. M.; DANESE, Isabelle ULg et al

in Molecular Microbiology (2000), 38(3), 543-51

Brucella melitensis 16M is a Gram-negative alpha2-proteobacterium responsible for abortion in goats and for Malta fever in humans. This facultative intracellular pathogen invades into and survives within ... [more ▼]

Brucella melitensis 16M is a Gram-negative alpha2-proteobacterium responsible for abortion in goats and for Malta fever in humans. This facultative intracellular pathogen invades into and survives within both professional and non-professional phagocytes. Signature-tagged mutagenesis (STM) was used to identify genes required for the in vivo pathogenesis of Brucella. A library of transposon mutants was screened in a murine infection model. Out of 672 mutants screened, 20 were not recovered after a 5 day passage in BALB/c mice. The attenuation of 18 mutants was confirmed using an in vivo competition assay against the wild-type strain. The 18 mutants were characterized further for their ability to replicate in murine macrophages and in HeLa cells. The sequences disrupted by the transposon in the mutants have homology to genes coding for proteins of different functional classes: transport, amino acid and DNA metabolism, transcriptional regulation, peptidoglycan synthesis, a chaperone-like protein and proteins of unknown function. The mutants selected in this study provide new insights into the molecular basis of Brucella virulence. [less ▲]

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See detailLes artisans-producteurs face aux problèmes de conservation.
Sindic, Marianne ULg; Rolland, Sandrine

in Dieta (2000), (20), 6-7

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See detailCurrent and future trends in groundwater vulnerability assessment
Gogu, Radu; Dassargues, Alain ULg

in Environmental Geology (2000), 39(6), 549-559

The concept of groundwater vulnerability is a useful tool for environmental planning and decision-making. Many different methods have been developed for assessing this vulnerability. Hydrogeologists have ... [more ▼]

The concept of groundwater vulnerability is a useful tool for environmental planning and decision-making. Many different methods have been developed for assessing this vulnerability. Hydrogeologists have failed to reach a consensus concerning the definitions of and reference terms for groundwater vulnerability assessment. Therefore, a review of vulnerability assessment and mapping methods providing a new classification system is necessary. This is focused on techniques that use the overlay and index class methods. New research challenges in vulnerability assessment are identified, especially the need for developing dynamic links between numerical models and overlay and index methods. [less ▲]

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See detailPhylogenetic analysis of the pearlfish Carapini (Ophidiiformes, Carapidae)
Parmentier, Eric ULg; Castillo Cabello, Gabriel ULg; Chardon, Michel ULg et al

in Acta Zoologica (2000), 81

Fishes of the tribe Carapini (Encheliophis and Carapus) share a noteworthy peculiarity: they shelter in holothurian echinoderms or bivalve hosts. Some species are considered parasitic, others commensal ... [more ▼]

Fishes of the tribe Carapini (Encheliophis and Carapus) share a noteworthy peculiarity: they shelter in holothurian echinoderms or bivalve hosts. Some species are considered parasitic, others commensal. This study focuses on the phylogeny of the tribe, using two other Carapidae species as an outgroup (Snyderidia canina and Onuxodon fowleri). Insofar as possible, the selected anatomical and behavioural characters where chosen in an ecomorphological perspective, as features that could be responses to various lifestyle-related constraints. Our character selection also took into account the fact that some features are (presumably) linked. Such features were grouped together as a single trait to avoid their overvaluation. This methodology enabled us to separate commensals from parasites, the former belonging to Carapus and the latter to Encheliophis. Carapus species reflect in their morphology the constraints imposed by a diet of hard, mobile, elusive prey, showing predator-type features: a strong dentition, a wide mouth opening, a robust food intake apparatus. On the other hand, the endoparasitic Encheliophis species show a generally weaker buccal apparatus and narrow mouth opening, in relation to the different constraints of their lifestyle where the diet constraints are less pronounced: they eat body parts of their host. We propose changes in both generic diagnoses and transfer three species from Encheliophis to Carapus. [less ▲]

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See detailReseña de Borges: desesperaciones aparentes y consuelos secretos, de Rafael Olea Franco (ed.)
Willson, Patricia ULg

in Variaciones Borges (2000), (9), 245-247

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See detailConstructions and applications of wavelets in Sobolev spaces
Bastin, Françoise ULg

in Revista Ciencias Matematicas (2000), 18(2), 145-177

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See detailComparaison des treillis classiques de type Warren, Pratt et Howe : optimisation et prédimensionnement sur base d'indicateurs morphologiques
Latteur, Pierre ULg; Samyn, Philippe; De Wilde, Patrick

in Revue Française de Génie Civil (2000), 4

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See detailPierre Bourdieu: Die Regeln der Kunst : Genese und Struktur des literarischen Feldes
Viehöver, Vera ULg

in Philosophischer Literaturanzeiger (2000), 53(4), 344-349

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See detailRelationship between the drift of macroinvertebrates and the activity of brown trout in a small stream
Giroux, F.; Ovidio, Michaël ULg; Philippart, Jean-Claude ULg et al

in Journal of Fish Biology (2000), 56(5), 1248-1257

Brown trout Saline trutta were most active in a small stream at night. dusk and dawn when drift rate was highest, but correlations between hourly drift rates and the trout's activity varied substantially ... [more ▼]

Brown trout Saline trutta were most active in a small stream at night. dusk and dawn when drift rate was highest, but correlations between hourly drift rates and the trout's activity varied substantially between individuals, between different dates for a single individual, and between different periods of the daily cycle. On some occasions. the trout were responsive to the total drift rate, either at night or during the day, and on others to the largest drifting organisms only (terrestrial organisms, adults of Ephemeroptera, Diptera and Trichoptera). The study supports the idea that trout adapt their activity pattern to the abundance of drifting prey, either as generalists towards any organism, or as specialists towards the largest ones. (C) 2000 The Fisheries Society of the British Isles. [less ▲]

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See detailTraitement médical des colites aiguës inflammatoires sévères
Belaiche, Jacques ULg; Louis, Edouard ULg

in Hépato-Gastro (2000), 7

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See detailDynamics and three-dimensional localization of ribosomal RNA within the nucleolus.
Thiry, Marc ULg; Cheutin, T.; O'Donohue, M. F. et al

in RNA (New York, N.Y.) (2000), 6(12), 1750-61

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely ... [more ▼]

Although rRNA synthesis, maturation, and assembly into preribosomal particles occur within the nucleolus, the route taken by pre-rRNAs from their synthetic sites toward the cytoplasm remains largely unexplored. Here, we employed a nondestructive method for the incorporation of BrUTP into the RNA of living cells. By using pulse-chase experiments, three-dimensional image reconstructions of confocal optical sections, and electron microscopy analysis of ultrathin sections, we were able to describe topological and spatial dynamics of rRNAs within the nucleolus. We identified the precise location and the volumic organization of four typical subdomains, in which rRNAs are successively moving towards the nucleolar periphery during their synthesis and processing steps. The incorporation of BrUTP takes place simultaneously within several tiny spheres, centered on the fibrillar centers. Then, the structures containing the newly synthesized RNAs enlarge and appear as compact ringlets disposed around the fibrillar centers. Later, they form hollow spheres surrounding the latter components and begin to fuse together. Finally, these structures widen and form large rings reaching the limits of the nucleoli. These results clearly show that the transport of pre-rRNAs within the nucleolus does not occur randomly, but appears as a radial flow starting from the fibrillar centers that form concentric rings, which finally fuse together as they progress toward the nucleolar periphery. [less ▲]

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See detailAssessment of muscle oxygenation in the horse by near infrared spectroscopy
Pringle, John; Roberts, C.; Art, Tatiana ULg et al

in Equine Veterinary Journal (2000), 32(1), 59-64

This study examined the ability of near infrared spectroscopy (NIRS) to noninvasively determine changes to muscle oxygenation in the resting horse. Five horses had (NIRS) performed over extremity muscle ... [more ▼]

This study examined the ability of near infrared spectroscopy (NIRS) to noninvasively determine changes to muscle oxygenation in the resting horse. Five horses had (NIRS) performed over extremity muscle while under general anaesthesia, first with 8 min limb ischaemia, then systemic hypoxaemia for 5 min. A second group of 6 awake horses had NIRS performed over extremity muscle while being administered hypoxic gas (F(I)O2 0.10) for 5 min, and after return to steady state, limb ischaemia was induced for an additional 5 min. In the anaesthetised horses' ischaemia induced marked and significant muscle deoxygenation of haemoglobin/myoglobin (P<0.01), with corresponding arterial saturation decreasing from 98.9 to 81.9%. Hypoxaemia induced small yet significant muscle deoxygenation (P<0.01) that was 3.2% of the ischaemia deoxygenation signal, with a corresponding decrease in arterial saturation from 98.6 to 90.4%. In the awake horses muscle deoxygenation was not detectable during hypoxia despite reduction of arterial saturation from 97.8 to 86.8%, whereas ischaemia induced rapid and significant deoxygenation of muscle (P<0.05), with corresponding reduction of venous saturation from 78.4 to 75.4%. In neither group of horses was there evidence of cytochrome aa3 reduction, despite complete ischaemia for up to 8 min. NIRS changes in the resting horse muscle clearly differed between ischaemia and hypoxaemia, and can readily show muscle deoxygenation in clinically relevant hypoxaemia in the horse under anaesthesia. Further, as the deoxygenation signal induced by ischaemia was clearly detectable above a background movement artefact, NIRS application to study of muscle oxygenation in the working horse should be explored. [less ▲]

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See detailL'écriture en chantier. Une brochure destinée aux enseignants du secondaire
Baye, Ariane ULg; Denooz, Régine

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2000), 7-8

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See detailUnimolecular reaction dynamics from kinetic energy release distributions. VI. Energy-selected ions
Lorquet, Jean-Claude ULg

in International Journal of Mass Spectrometry (2000), 201(1-3), 59-67

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The ... [more ▼]

The kinetic energy distribution (KERD) determined by Brand et al. [Chem. Phys. 76 (1983) 111] for the iodine loss from energy-selected iodopropane ions has been analyzed by the maximum entropy method. The entropy deficiency DS has been determined and the value of e(-DS), which measures the efficiency of phase-space sampling, has been found equal to about 96%, thus corresponding to a nearly fully statistical situation. The phase space theory of Klots describes a slightly more constrained situation with e(-DS) ≃ 77%. A rapid determination of the sampled fraction of phase space is possible from energy-selected KERDs, based on the fact that there exists a direct relationship between the efficiency e(-DS) and the reduced maximum of the KERD ε(red)/(M) = ε(M) (E)/<ε>(E). The product ε(M)(E) P(ε(M)/E) or ε(red)/(M) P(ε(red)/(M)) holds the same property. (C) 2000 Elsevier Science B.V. [less ▲]

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See detailSibling cannibalism in dorada under experimental conditions. II. Effect of initial size heterogeneity, diet and light regime on early cannibalism
Baras, E.; Maxi, M. Y.; Ndao, J. et al

in Journal of Fish Biology (2000), 57

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See detailNeurodegenerative and morphogenic changes in a mouse model of temporal lobe epilepsy do not depend on the expression of the calcium-binding proteins parvalbumin, calbindin, or calretinin.
Bouilleret, V.; Schwaller, B.; Schurmans, Stéphane ULg et al

in Neuroscience (2000), 97(1), 47-58

The functional role of the calcium-binding proteins parvalbumin, calretinin, and calbindin D-28k for epileptogenesis and long-term seizure-related alterations of the hippocampal formation was assessed in ... [more ▼]

The functional role of the calcium-binding proteins parvalbumin, calretinin, and calbindin D-28k for epileptogenesis and long-term seizure-related alterations of the hippocampal formation was assessed in single- and double-knockout mice, using a kainate model of mesial temporal lobe epilepsy. The effects of a unilateral intrahippocampal injection of kainic acid were assessed at one day, 30 days, and four months post-injection, using various markers of GABAergic interneurons (GABA-transporter type 1, GABA(A)-receptor alpha1 subunit, calretinin, calbindin D-28k, somatostatin, and neuropeptide Y). Parvalbumin-deficient, parvalbumin/calbindin-deficient, and parvalbumin/calretinin-deficient mice exhibited no difference in cytoarchitecture of the hippocampal formation and in the number, distribution, or morphology of interneurons compared to wild-type mice. Likewise, mutant mice were not more vulnerable to acute kainate-induced excitotoxicity or to long-term effects of recurrent focal seizures, and exhibited the same pattern of neurochemical alterations (e.g., bilateral induction of neuropeptide Y in granule cells) and morphogenic changes (enlargement and dispersion of dentate gyrus granule cells) as wild-type animals. Quantification of interneurons revealed no significant difference in neuronal vulnerability among the genotypes.These results indicate that the calcium-binding proteins investigated here are not essential for determining the neurochemical phenotype of interneurons. Furthermore, they are not protective against kainate-induced excitotoxicity in this model, and do not appear to modulate the overall level of excitability of the hippocampus. Finally, seizure-induced changes in gene expression in granule cells, which normally express high levels of calcium-binding proteins, apparently were not affected by the gene deletions analysed [less ▲]

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See detailThe increase of the ionospheric activity as measured by GPS
Warnant, René ULg; Pottiaux, Eric

in Earth, Planets, and Space [=EPS] (2000), 52(11), 1055-1060

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See detailLinear growth and final height after treatment for Cushing's disease in childhood.
LEBRETHON, Marie-Christine ULg; Grossman, A. B.; Afshar, F. et al

in The Journal of clinical endocrinology and metabolism (2000), 85(9), 3262-5

Cushing's disease is associated with growth failure in childhood and adolescence. Growth and final height were analyzed in 10 patients who were cured or in remission after treatment of Cushing's disease ... [more ▼]

Cushing's disease is associated with growth failure in childhood and adolescence. Growth and final height were analyzed in 10 patients who were cured or in remission after treatment of Cushing's disease. Seven males and 3 females, aged 6.8-17.6 yr (bone age, 3.3-15.4 yr), had transsphenoidal surgery, which was combined with pituitary irradiation (4,500 cGy in 25 fractions) in 5 patients. At presentation, 5 patients were prepubertal (males), and 5 were pubertal (2 males and 3 females). The mean height SD score was -2.15 +/-1.26 (range, -0.21 to -4.32) compared with mean target height SD score of -0.43 +/- 0.58. Height velocity in 6 patients was subnormal (0.9-3.8 cm/yr). After treatment, short-term height velocity, over a mean interval of 0.57 yr, in 8 patients not receiving human GH (hGH) therapy, was variable (range, 0.8-7.6 cm/yr). GH stimulation tests (insulin tolerance test/glucagon) in 9 subjects showed peak GH levels of 0.5-20.9 mU/L. Eight were treated with hGH (14 IU/m2 wk), combined in 2 girls and 1 boy with a GnRH analog. After 1 yr of hGH, the mean height SD score had increased from -2.45 +/- 1.0 at initiation of hGH to -2.07 +/- 1.2 (P = 0.01). GH therapy was continued until final height or latest assessment. The mean final height SD score (n = 6) was - 1.24 +/- 1.38, and at the latest assessment the mean height SD score (n = 4) was - 1.52 +/- 1.33. Combining these 2 groups, the mean height so score was -1.36 +/- 1.29. The difference between final or latest height SD score and target height SD score was 0.93 +/- 1.13, i.e. less (P = 0.005) than the difference between height and target height SD score of 1.72 +/- 1.26 at presentation. In conclusion, catch-up and favorable long-term growth was seen after treatment for Cushing's disease. Posttreatment GH deficiency was frequent, and early hGH replacement may have contributed to the encouraging outcome. [less ▲]

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See detailNumerical discretization of rotated diffusion operators in ocean models
Beckers, Jean-Marie ULg; Burchard, Hans; Deleersnijder, Eric et al

in Monthly Weather Review (2000), 128(8), 2711-2733

A method to improve the behavior of the numerical discretization of a rotated diffusion operator such as, for example, the isopycnal diffusion parameterization used in large-scale ocean models based on ... [more ▼]

A method to improve the behavior of the numerical discretization of a rotated diffusion operator such as, for example, the isopycnal diffusion parameterization used in large-scale ocean models based on the so-called z-coordinate system is presented. The authors then focus exclusively on the dynamically passive tracers and analyze some different approaches to the numerical discretization. Monotonic schemes are designed but are found to be rather complex, while simpler, linear schemes are shown to produce unphysical undershooting and overshooting. It is suggested that the choice of an appropriate discretization method depends on the importance of the rotated diffusion in a given simulation, whether the field to be diffused is dynamically active or not. [less ▲]

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See detailMedium-size droplets of methyl ricinoleate are reduced by cell-surface activity in the γ-decalactone production by Yarrowia lipolytica
Waché, Y.; Bergmark, K.; Courthaudon, J.-L. et al

in Letters in Applied Microbiology (2000), 30(3), 183-187

Size of methyl ricinoleate droplets during biotransformation into γ-decalactone by Yarrowia lipolytica was measured in both homogenized and non-homogenized media. In non-homogenized but shaken medium ... [more ▼]

Size of methyl ricinoleate droplets during biotransformation into γ-decalactone by Yarrowia lipolytica was measured in both homogenized and non-homogenized media. In non-homogenized but shaken medium, droplets had an average volume surface diameter d 32 of 2.5 μm whereas it was 0.7 μm in homogenized and shaken medium. But as soon as yeast cells were inoculated, both diameters became similar at about 0.7 μm and did not vary significantly until the end of the culture. The growth of Y. lipolytica in both media was very similar except for the lag phase which was lowered in homogenized medium conditions. [less ▲]

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See detailIschaemic Colitis Following Aortoiliac Surgery
VAN DAMME, Hendrik ULg; CREEMERS, Etienne ULg; Limet, Raymond ULg

in Acta Chirurgica Belgica (2000), 100(1), 21-7

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive ... [more ▼]

Ischaemic colitis following aortoiliac surgery is a feared complication. Its frequency varies from 7% after repair of ruptured abdominal aortic aneurysm (AAA) to 0.6% after bypass for aortoiliac occlusive disease (AOD). In order to analyse predisposing factors and outcome of ischaemic colitis, the authors reviewed their clinical experience from 1988 to 1998. It concerns 28 cases (16 ruptured AAA, 7 elective AAA, 5 OAD) of clinically evident colonic ischaemia. This means an incidence of 7% after repair of ruptured AAA, 0.6% after elective AAA repair, and 0.8% after bypass for AOD. Transmural necrosis (grade 3) was observed in 21 patients, grade 2 ischaemia in 5 patients, and grade 1 ischaemia in 2 patients. Fifteen patients with grade 3 ischaemia underwent colectomy (Hartmann's procedure) with a mortality rate of 66%. All non operated grade 3 patients died. Overall, 16 of the 28 patients died at hospital (57% mortality rate). None of the patients with mild (grade 2 or 1) colonic ischaemia died. Profound hypovolaemic shock and inflammatory AAA were the only significant predisposing factors leading to colonic ischaemia. Associated colon revascularization could not avoid the evolution to colon necrosis in four patients. Reimplantation of a patent inferior mesenteric artery or an internal iliac artery was performed in only 4.8% of all aortoiliac reconstructions, and did not influence the development of ischaemic colitis. The authors conclude that a more liberal use of postoperative sigmoidoscopy could allow detecting colonic ischaemia at an earlier stage and reduce ensuing mortality. A reinforced effort to restore or preserve colonic vascularization could lower the incidence of colonic ischaemia following aortoiliac surgery. [less ▲]

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See detailWegwijs in de vele benamingen van de veelvormige pathogeen Escherichia coli
Mainil, Jacques ULg

in Vlaams Diergeneeskundig Tijdschrift (2000), 69

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See detailExtensions des techniques de reparation valvulaire mitrale: chirurgie de l'endocardite et des tumeurs valvulaires
Radermecker, M. A.; Gach, Olivier ULg; Henrottaux, G. et al

in Revue Médicale de Liège (2000), 55(10), 950-3

Mitral valve repair has demonstrated its superiority over valve replacement. Mitral valve repair constitutes the optimal therapeutic option in case of degenerative dystrophic, rheumatic, congenital or ... [more ▼]

Mitral valve repair has demonstrated its superiority over valve replacement. Mitral valve repair constitutes the optimal therapeutic option in case of degenerative dystrophic, rheumatic, congenital or ischemic mitral valve disease. These surgical techniques can also be successfully and advantageously applied in case of bacterial endocarditis or tumoral valvular disease. We report a case of staphylococcal endocarditis and another case of posterior leaflet fibroelastoma to show the place of conservative mitral surgery in these unusual indications. [less ▲]

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See detailMechanisms of reduced and compensatory growth.
Hornick, Jean-Luc ULg; Van Eenaeme, Christian ULg; Gerard, O. et al

in Domestic Animal Endocrinology (2000), 19(2), 121-32

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone ... [more ▼]

Growth is an integrated process, resulting from the response of cells dependent on the endocrine status and nutrient availability. During feed restriction, the production and secretion of growth hormone (GH) by the pituitary gland are enhanced, but the number of GH receptors decreases. Changes of GH binding proteins induce GH resistance and are followed by reduced insulin-like growth factor-I (IGF-I) secretion. On the other hand, high circulating levels of GH enhance the mobilization of fatty acids, which are used to support energy requirements. Thus, when feed restriction in growing animals is moderate, there is mainly protein but barely fat accretion. By contrast, a severe feed restriction enhances the release of catabolic hormones and stimulates, from muscle cells, the liberation of amino acids, which are used by hepatocytes for gluconeogenesis. During refeeding and compensatory growth, the secretion of insulin is sharply enhanced and plasma GH concentrations remain high. This situation probably allows more nutrients to be used for growth processes. The role of plasma IGF-I during compensatory growth is not clear and must be explained in connection with changes of its binding proteins. Thyroxin and 3,5,3'-triiodothyronine seem to have a permissive effect on growth. The simultaneous occurrence of puberty with refeeding can exert a synergistic effect on growth. Initially, compensatory growth is characterized by the deposition of very lean tissue, similar as during feed restriction. This lasts for some weeks. Then, protein synthesis decreases and high feed intake leads to increased fat deposition. [less ▲]

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See detailAlteration of thyroid hormones, insulin-like growth factor-I (IGF-I) and IGFBPs in finishing calves treated with dexamethasone
Bertozzi, Carlo; Massart, Serge; Darras, Veerle et al

in Canadian Journal of Animal Science (2000), 80

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See detailCompétition et choix du partenaire sexuel chez les primates
Huynen, Marie-Claude ULg

in Cahiers d'Ethologie (2000), 20(1), 85-112

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See detailComment j'explore...une mycobactériose cutanée atypique
Henry, Frédérique ULg; Hayette, Marie-Pierre ULg; Melin, Pierrette ULg et al

in Revue Médicale de Liège (2000), 55(12), 1058-1063

Atypical mycobacteriosis affecting the skin are diverse and their treatments are different as well. These diseases show an increasing prevalence. The contamination occurs from the environment while ... [more ▼]

Atypical mycobacteriosis affecting the skin are diverse and their treatments are different as well. These diseases show an increasing prevalence. The contamination occurs from the environment while interhuman transmission does not occur. [less ▲]

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See detailA survey on staging and treatment in uterine cervical carcinoma in the Radiotherapy Cooperative Group of the European Organization for Research and Treatment of Cancer
Coucke, Philippe ULg; Maingon, P; Ciernik, I et al

in Radiotherapy & Oncology (2000), 54

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the ... [more ▼]

Abstract Background: The treatment outcome of advanced stage uterine cervical carcinoma remains unsatisfactory. In order to elaborate a novel trial within The Radiotherapy Cooperative Group (RCG) of the European Organization for Research and Treatment of Cancer (EORTC), we conducted a survey in 1997±1998 to determine the variability of pre-treatment assessment and treatment options. The variability of choosing surgery, de®ned radiation therapy techniques and chemotherapy are investigated, as well as the center's choices of future treatment strategies. Methods: Fifty two of 81 RCG centers from the RCG have participated in the survey. As one would expect, there is a large variation in the techniques used for pretreatment evaluation and treatment options. There is no `standard' for reporting acute and late side effects. Chemotherapy is used neither systematically nor uniformly, and some centers continue to use neadjuvant chemotherapy modalities. Results: Furthermore, the survey reveals that there is a strong demand for the reduction of overall treatment-time, for clinical investigation of novel combined modality treatment strategies, especially chemo±radiation therapy, and also for the use of new radiation sensitizers. Conclusion:We conclude that a more homogeneous approach to the pretreatment evaluation as well as treatment techniques is required in order to allow adequate quality control in any future trial of the RCG in the EORTC.q2000 Elsevier Science Ireland Ltd. All rights reserved. [less ▲]

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See detailImmunocytochemical localization of ionotropic glutamate receptors subunits in the adult quail forebrain
Cornil, Charlotte ULg; Foidart, Agnès ULg; Minet, Arlette ULg et al

in Journal of Comparative Neurology (The) (2000), 428

The excitatory amino acid glutamate is implicated in the central control of many neuroendocrine and behavioral processes. The ionotropic glutamate receptors are usually divided into the N-methyl-D ... [more ▼]

The excitatory amino acid glutamate is implicated in the central control of many neuroendocrine and behavioral processes. The ionotropic glutamate receptors are usually divided into the N-methyl-D-aspartate (NMDA) and non-NMDA (kainate and AMPA) subtypes. Subunits of these receptors have been cloned in a few mammalian species. Information available in birds is more limited. In quail, we recently demonstrated that glutamate agonists (kainate, AMPA, and NMDA) rapidly (within minutes) and reversibly decrease in vitro aromatase activity like several other manipulations affecting intracellular HCa21 pools. Aromatase catalyzes the conversion of androgens into estrogens which is a limiting step in the control by testosterone of many behavioral and physiologic processes. Therefore, glutamate could control estrogen production in the brain, but the anatomic substrate supporting this effect is poorly understood. In quail, aromatase is mainly localized in the preoptic-hypothalamic-limbic system. We visualized here the distribution of the major ionotropic glutamate receptors in quail by immunocytochemical methods by using commercial primary antibodies raised against rat glutamate receptor 1 and receptors 2-3 (GluR1, GluR2/3: AMPA subtype, Chemicon, CA), rat glutamate receptors 5-7 (GluR5-7: kainate subtype, Pharmingen, CA), and rat NMDA receptors (NMDAR1, Pharmingen, CA). Dense and specific signals were obtained with all antibodies. The four types of receptors are broadly distributed in the brain, and, in particular, immunoreactive cells are identified within the major aromatase cell groups located in the medial preoptic nucleus, ventromedial hypothalamus, nucleus striae terminalis, and nucleus taeniae. Dense specific populations of glutamate receptor immunoreactive cells are also present with a receptor subtype-specific distribution in broad areas of the telencephalon. The distribution of glutamate receptors, therefore, is consistent with the idea that these receptors could be located at the surface of aromatase-containing cells and mediate the rapid regulation of aromatase activity in a direct manner. [less ▲]

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See detailL'entérotoxémie bovine en Belgique. II. Epizootiologie élémentaire et pathologie descriptive.
Manteca, Christophe; Daube, Georges ULg; Jauniaux, Thierry ULg et al

in Annales de Médecine Vétérinaire (2000), 145

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See detailRecombinant prolactin Receptor Extracellular Domain of Rainbouw trout (Oncorhynchus mykiss): subcloning, preparation and characterization
Sandowski, Y.; Cohen, Y.; Le Rouzic, P. et al

in General and Comparative Endocrinology (2000), 118

The cDNA of the extracellular domain of rainbow trout (Oncorhynchus mykiss) prolactin receptor (trPRLR-ECD) was cloned in the prokaryotic expression vector pMON to enable its expression in Escherichia ... [more ▼]

The cDNA of the extracellular domain of rainbow trout (Oncorhynchus mykiss) prolactin receptor (trPRLR-ECD) was cloned in the prokaryotic expression vector pMON to enable its expression in Escherichia coli after induction with nalidixic acid. The bacterially expressed trPRLR-ECD protein, contained within the refractile body pellet, was solubilized in 4.5 M urea, refolded, and purified on a Q-Sepharose column, pH 8, by stepwise elution with NaCl. The bioactive monomeric 26-kDa fraction was eluted in 0.2 M NaCl, yielding 20 mg/2.5 L of induced culture. The purified protein was over 98% homogeneous, as shown by SDS-PAGE in the presence or absence of reducing agent and by chromatography on a Superdex column. Binding experiments using [125I]ovine placental lactogen (oPL) as a ligand revealed that human growth hormone (hGH), oPL, and ovine prolactin (oPRL) were the most effective competitors, with respective IC50 values of 1.32, 2.27, and 2.70 nM. Chicken (ch) PRL did not compete at all, and homologous trPRL was much less effective, with a corresponding IC50 value of 1826 nM. Gel-filtration was used to determine the stoichiometry of trPRLR-ECD's interaction with oPL, hGH, and oPRL. Only oPL yielded a 2:1 complex, whereas hGH and oPRL formed only 1:1 complexes, with excess trPRLR-ECD being seen at the initial 2:1 trPRLR-ECD:hGH or trPRLR-ECD:oPRL ratios. No studies were performed with chPRL because of its inability to compete with [125I]oPL or with trPRL because of its low affinity toward trPRLR-ECD. The present results agree with previous findings indicating, as in mammals, that homologous PRL interacts transiently with its receptor and suggest that transient homologous PRL-induced homodimerization of the receptor is sufficient to initiate a biological signal, despite the fact that, in classical binding experiments, only low specific binding can be detected. [less ▲]

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See detailCompte rendu de : Verhoogt-Vleeming, The Two Faces of Graeco-Roman Egypt
Rochette, Bruno ULg

in Bibliotheca Orientalis (2000), 57(5/6), 606-609

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See detailNon-alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss.
Luyckx, Françoise ULg; Lefebvre, Pierre ULg; Scheen, André ULg

in Diabètes & Métabolism (2000), 26(2), 98-106

Non-alcoholic steatohepatitis (NASH) is a disease of emerging identity and importance, and is now considered as one of the commonest liver diseases in western countries. It is frequently associated with ... [more ▼]

Non-alcoholic steatohepatitis (NASH) is a disease of emerging identity and importance, and is now considered as one of the commonest liver diseases in western countries. It is frequently associated with severe obesity, especially abdominal adiposity, and is intimately related to various clinical and biological markers of the insulin resistance syndrome. Especially, both the prevalence and the severity of liver steatosis are related to male sex, body mass index, waist circumference, hyperinsulinaemia, hypertriglyceridaemia and impaired glucose tolerance or type 2 diabetes. A substantial weight loss following gastroplasty is accompanied by a marked reduction in the prevalence and the severity of the various biological abnormalities of the metabolic syndrome and, concomitantly, by an important regression of liver steatosis in most obese patients. However, in some patients, this rapid and drastic weight loss may result in a mild increase in inflammatory lesions (hepatitis), despite the regression of steatosis, which might result from the rapid mobilization of fatty acids or cytokines from adipose tissue, especially visceral fat. The intimate relationship between NASH and obesity leads to the concept that NASH may be considered as another disease of affluence, as is the insulin resistance syndrome and perhaps being part of it. [less ▲]

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