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See detailHematopoietic cell transplantation: five decades of progress.
Baron, Frédéric ULg; Storb, Rainer; Little, Marie-Terese

in Archives of Medical Research (2003), 34(6), 528-44

During the past 50 years, the role of allogeneic hematopoietic cell transplantation (HCT) has changed from a desperate therapeutic maneuver plagued by apparently insurmountable complications to a curative ... [more ▼]

During the past 50 years, the role of allogeneic hematopoietic cell transplantation (HCT) has changed from a desperate therapeutic maneuver plagued by apparently insurmountable complications to a curative treatment modality for thousands of patients with hematologic diseases. Now, cure rates following human leukocyte antigen (HLA) allogeneic HCT with matched siblings exceed 85% for some otherwise lethal diseases, such as chronic myeloid leukemia, aplastic anemia, or thalassemia. In addition, the recent development of non-myeloablative conditioning and stem cell transplantation has opened the way to include elderly patients with a wide variety of hematologic malignancies. Further progress in adoptive transfer of T cell populations with relative tumor specificity would make the transplant procedure more effective and would extend the use of allogeneic HCT for treatment of non-hematopoietic malignancies. [less ▲]

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See detailTowards an Understanding of Hafting: the macro- and microscopic evidence
Rots, Veerle ULg

in Antiquity (2003), 77(298), 805-815

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See detailVitamine E: état des connaissances chez les carnivores domestiques. II Métabolisme, besoins et apports
Cuvelier, Christine ULg; Dotreppe, Olivier ULg; Diez, Marianne ULg et al

in Annales de Médecine Vétérinaire (2003), 147(6, DEC-JAN), 367-382

This paper aims to present the metabolism of vitamin E and the allowances and requirements in men and domestic carnivores. The mechanisms of absorption, distribution, storage and excretion of vitamin E ... [more ▼]

This paper aims to present the metabolism of vitamin E and the allowances and requirements in men and domestic carnivores. The mechanisms of absorption, distribution, storage and excretion of vitamin E are explained. The metabolism particularities of this vitamin due to the existence of the a-Tocopherol Transfer Protein are developed. The concentrations in lipoproteins and plasma are presented along with their variation factors. Vitamin E units, estimation of requirements and dietary allowances and tolerable upper intake level in men and domestic carnivores are also reviewed. Finally, the use of vitamin E in the petfood industry is discussed. [less ▲]

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See detailLa servitude légale d'enclave : un tour d'horizon
Boufflette, Sophie ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailInfluence of response factors on determining equilibrium association constants of non-covalent complexes by electrospray ionization mass spectrometry
Gabelica, Valérie ULg; Galic, Nives; Rosu, Frédéric ULg et al

in Journal of Mass Spectrometry [=JMS] (2003), 38(5), 491-501

A method for determining the equilibrium association constant of a complexation reaction A + B <=> AB by electrospray ionization mass spectrometry is described. The method consists in measuring the ... [more ▼]

A method for determining the equilibrium association constant of a complexation reaction A + B <=> AB by electrospray ionization mass spectrometry is described. The method consists in measuring the relative intensities of the peaks corresponding to A and to AB in equimolar A–B solutions at different concentrations C0. The results are fitted by a non-linear least-squares procedure, with the two variable parameters being the equilibrium association constant Ka and a factor R, defined by I(AB)/I.A/ = R× [AB]/[A]. The factor R is the ratio between the response factors of AB and A, and corrects for the relative electrospray responses of the complex and the free substrate A, mass discrimination of instrumental origin and/or moderate in-source dissociation. The method is illustrated with the following two systems: complexes between a double-stranded 12-base pair oligonucleotide and minor groove binders, and cyclodextrin complexeswith a,!-dicarboxylic acids. For the oligonucleotide complexes, it is found that the response of the complex is not dramatically different to the response of the free oligonucleotide duplex, as the double helix conformation is disturbed by the drug only to a minor extent. In the case of cyclodextrin complexes, these complexes were found to have a much higher response than free cyclodextrin. This may be due to the fact that cyclodextrin is neutral in solution, whereas the complex is charged, but it can also stem from the fact that a significant proportion of the complex is in a non-inclusion geometry. The present method requires the exact determination of the concentrations of the reactants and is applicable to 1 : 1 complexes. [less ▲]

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See detailVirus infections in pathogenesis of type 1 diabetes
Brilot, Fabienne; Geenen, Vincent ULg

in International Diabetes Monitor (2003), 14

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See detailRecent advances in the study of lanthanide atoms and ions
Biémont, Emile ULg; Quinet, Pascal ULg

in Physica Scripta (2003), T105

We present an overview of the recent developments concerning the spectroscopic properties of lanthanide atoms and ions (Z = 57-71). This review is focussed on the advances made during the past twenty ... [more ▼]

We present an overview of the recent developments concerning the spectroscopic properties of lanthanide atoms and ions (Z = 57-71). This review is focussed on the advances made during the past twenty years regarding the analysis of the spectra, the transition probabilities, the radiative lifetimes and also the hyperfine structures and isotope shifts. Theoretical aspects as well as experimental measurements are both covered in this paper including bibliographical references up to the end of 2001. Some astrophysical implications of the new atomic data concerning the chemical composition of the sun are briefly reviewed. Emphasis is also put on the new database D.R.E.A.M. developed on a web site of Mons University in Belgium. [less ▲]

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See detailTopical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.
Humbert, Philippe G; Haftek, Marek; Creidi, Pierre et al

in Experimental Dermatology (2003), 12(3), 237-44

Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway. Photoprotective properties of topically applied vitamin C have also been demonstrated, placing this ... [more ▼]

Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway. Photoprotective properties of topically applied vitamin C have also been demonstrated, placing this molecule as a potential candidate for use in the prevention and treatment of skin ageing. A topically applied cream containing 5% vitamin C and its excipient were tested on healthy female volunteers presenting with photoaged skin on their low-neck and arms in view to evaluate efficacy and safety of such treatment. A double-blind, randomized trial was performed over a 6-month period, comparing the action of the vitamin C cream vs. excipient on photoaged skin. Clinical assessments included evaluation at the beginning and after 3 and 6 months of daily treatment. They were performed by the investigator and compared with the volunteer self assessment. Skin relief parameters were determined on silicone rubber replicas performed at the same time-points. Cutaneous biopsies were obtained at the end of the trial and investigated using immunohistochemistry and electron microscopy. Clinical examination by a dermatologist as well as self-assessment by the volunteers disclosed a significant improvement, in terms of the 'global score', on the vitamin C-treated side compared with the control. A highly significant increase in the density of skin microrelief and a decrease of the deep furrows were demonstrated. Ultrastructural evidence of the elastic tissue repair was also obtained and well corroborated the favorable results of the clinical and skin surface examinations. Topical application of 5% vitamin C cream was an effective and well-tolerated treatment. It led to a clinically apparent improvement of the photodamaged skin and induced modifications of skin relief and ultrastructure, suggesting a positive influence of topical vitamin C on parameters characteristic for sun-induced skin ageing. [less ▲]

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See detailOptimisation du protocole GPG
Hanzen, Christian ULg; Boudry, B.

in Point Vétérinaire (2003), 34(240), 44-46

Les facteurs susceptibles d’influencer les performances de reproduction permises par le protocole GPG sont multiples. L’apparition de l’oestrus et sa durée, la fréquence de l’ovulation, la croissance ... [more ▼]

Les facteurs susceptibles d’influencer les performances de reproduction permises par le protocole GPG sont multiples. L’apparition de l’oestrus et sa durée, la fréquence de l’ovulation, la croissance folliculaire, tout comme la progestéronémie, sont susceptibles d’être influencés par le stade du cycle auquel le protocole est mis en place. Le taux de gestation est d’autant plus élevé que la proportion d’animaux en anoestrus dans le troupeau est faible. Ceci explique sans doute en partie pourquoi la fertilité se trouve améliorée lorsque l’insémination suivant le traitement est effectuée après le 75e jour de lactation. De même, des résultats préliminaires confirment l’application potentielle du protocole au traitement des kystes ovariens. [less ▲]

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See detailCalorimetry of cationic liposome-DNA complex and intracellular visualization of the complexes.
Elouahabi, Abdelatif; Thiry, Marc ULg; Pector, Veronique et al

in Methods in Enzymology (2003), 373

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See detailMagnetic and mossbauer spectral study of ErFe11Ti and ErFe11TiH
Piquer, C.; Hermann, Raphaël ULg; Grandjean, Fernande ULg et al

in Journal of Applied Physics (2003), 93(6), 3414-3421

X-ray diffraction, isothermal magnetization at 5 and 300 K, ac magnetic susceptibility measurements between 5 and 200 K, and iron-57 Mossbauer spectral measurements between 4.2 and 295 K have been carried ... [more ▼]

X-ray diffraction, isothermal magnetization at 5 and 300 K, ac magnetic susceptibility measurements between 5 and 200 K, and iron-57 Mossbauer spectral measurements between 4.2 and 295 K have been carried out on ErFe11Ti and ErFe11TiH. Hydrogen uptake has been measured by gravimetric analysis and the insertion of hydrogen into ErFe11Ti increases its magnetization, magnetic hyperfine fields, and isomer shifts as a result of the associated lattice expansion. Peaks and steplike changes in both the real and imaginary components of the ac magnetic susceptibility are observed at similar to50 and 40 K for ErFe11Ti and ErFe11TiH, respectively, and are assigned to spin-reorientation transitions resulting from the temperature dependence of the sixth-order Stevens crystal-field term of erbium. The Mossbauer spectra have been analyzed with a model which considers both these spin reorientations and the distribution of titanium atoms in the near-neighbor environment of the three crystallographically distinct iron sites. The assignment and the temperature dependencies of the hyperfine fields and isomer shifts are in complete agreement with the Wigner-Seitz cell analysis of the three iron sites in ErFe11Ti and ErFe11TiH. The changes in the hyperfine field and isomer shift with the number of titanium near neighbors of the three iron sites are in agreement with the values observed for related titanium-iron intermetallic compounds. (C) 2003 American Institute of Physics. [less ▲]

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See detailPetrology of the Lyngdal granodiorite (southern Norway) and the role of fractional crystallization in the genesis of Proterozoic rapakivi-like granites
Bogaerts, Michel; Scaillet, Bruno; Liégeois, Jean-Paul ULg et al

in Precambrian Research (2003), 124(2-4), 149-184

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See detailThe use of data assimilation in coupled hydrodynamic, ecological and biogeochemical models of the ocean
Grégoire, Marilaure ULg; Brasseur, Pierre; Lermusiaux, Pierre

in Journal of Marine Systems (2003), 40-41(1-3), 405

The International Lie`ge Colloquium on Ocean Dynamics is organized annually. The topic differs from year to year in an attempt to address, as much as possible, recent problems and incentive new subjects ... [more ▼]

The International Lie`ge Colloquium on Ocean Dynamics is organized annually. The topic differs from year to year in an attempt to address, as much as possible, recent problems and incentive new subjects in oceanography. Assembling a group of active and eminent scientists from various countries and often different disciplines, the Colloquia provide a forum for discussion and foster a mutually beneficial exchange of information opening on to a survey of recent discoveries, essential mechanisms, impelling question marks and valuable recommendations for future research. The objective of the 2001 Colloquium was to evaluate the progress of data assimilation methods in marine science and, in particular, in coupled hydrodynamic, ecological and bio-geo-chemical models of the ocean. [less ▲]

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See detailPostexposure management of hepatitis A, B or C: treatment, postexposure prophylaxis and recommendations
Delwaide, Jean ULg

in Acta Gastro-Enterologica Belgica (2003), 66(3), 250-254

Although there is no consensus on the best management of acute hepatitis C or on optimal strategy of follow-up after potential contamination, certain guidelines can nevertheless be proposed for the care ... [more ▼]

Although there is no consensus on the best management of acute hepatitis C or on optimal strategy of follow-up after potential contamination, certain guidelines can nevertheless be proposed for the care of these patients in practice. It is now recommended that acute hepatitis C be treated by interferon monotherapy in the presence of a C viremia, detectable by polymerase chain reaction, and an elevation of the transaminases. The earlier the treatment is started after appearance of symptoms, the more effective it is. Management of a potentially contaminated individuals consists of screening for the C virus as early as the fifteenth day after the potentially contaminating act and, in the case of virus transmission, starting interferon treatment as soon as elevation of the transaminases appears. No special precautions are to be taken by the person potentially contaminated for avoiding possible secondary C virus transmission during the follow-up period. In the case of acute hepatitis B, antiviral treatment should not be started, in view of the high percentage of spontaneous recoveries and the potentially negative effect of treatment on the chances of spontaneous recovery. Post-exposure prophylaxis by anti-hepatitis B immunoglobin injections and/or vaccination should be considered after evaluation of the hepatitis B surface antigen status of the source and of the vaccination and vaccine-response status of the exposed person. The classic scheme for selecting the most appropriate postexposure prophylaxis is reminded. In post-exposure prophylaxis for hepatitis A virus, although there have been no studies comparing the effectiveness of vaccination with that of immunoglobin injections, it is at present proposed to provide only vaccination. The target groups eligible for post-exposure prophylaxis are evoked. [less ▲]

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See detailNote sous Cass., 29 novembre 2001
Biquet, Christine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailEstimating internal pelvic sizes using external body measurements in the double-muscled Belgian Blue beef breed
Coopman, F.; de Smet, S.; Gengler, Nicolas ULg et al

in Animal Science (2003), 76(Part 2), 229-235

In the double-muscled (DM) Belgian Blue beef (BBB) breed, caesarean section (CS) is being applied systematically as a management tool to prevent dystocia. As a matter of fact, CS is the only possible way ... [more ▼]

In the double-muscled (DM) Belgian Blue beef (BBB) breed, caesarean section (CS) is being applied systematically as a management tool to prevent dystocia. As a matter of fact, CS is the only possible way of calving in the breed. High birth weight and a relatively small pelvic area are the main causes of dystocia and, in the DM-BBB breed, the reasons for the systematically applied CS. Selection for lower birth weight and larger pelvic sizes might reduce dystocia and routine CS. Few data on inner pelvic sizes of pedigree animals are available. Using external measurements to estimate the inner pelvic sizes might be an option to resolve this problem. In this study, animals of the DM-BBB breed were measured and weighed on farms and in abattoirs. External and internal pelvic sizes increased with live weight and age of the animals. Gender had a significant influence on inner pelvic traits. Increased muscular conformation was associated with decreased inner pelvic dimensions. Models with weight, gender, age, withers height and outer pelvic width (TcTc) can be used to estimate inner pelvic sizes (R-2 between 0.35 and 0.77). The estimated inner pelvic sizes can then be used to genetically evaluate pelvic traits in the DM-BBB breed. Improving weight, withers height and TcTc width in combination with lowering muscular conformation may help to decrease the high rate of caesarean section in the DM-BBB. [less ▲]

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See detailLa majoration des quotités insaisissables pour enfant à charge
Georges, Frédéric ULg

in Actualités du Droit (2003)

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See detailA low rate of trisomy 21 in twin-pregnancies: A cytogenetics retrospective study of 278 cases
Jamar, Mauricette ULg; Lemarchal, C.; Koulischer, Lucien ULg et al

in Genetic Counseling (2003), 14(4), 395-400

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See detailL'image du mois. Sous le pont myocardique coule la coronaire.
ROUSSEAU, Anne-Françoise ULg; MIEVIS, Eric

in Revue Médicale de Liège (2003), 58(10), 601-604

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See detailThe treatment of sporadic versus MEN1-related pituitary adenomas.
Beckers, Albert ULg; Betea, Daniela ULg; Valdes Socin, Hernan Gonzalo ULg et al

in Journal of Internal Medicine (2003), 253(6), 599-605

The treatment of pituitary tumours strongly depends on their clinical presentation. In general, the treatment aims are reducing tumour volume and/or decreasing hormone hypersecretion. It relies on single ... [more ▼]

The treatment of pituitary tumours strongly depends on their clinical presentation. In general, the treatment aims are reducing tumour volume and/or decreasing hormone hypersecretion. It relies on single or a combination of three different methods: surgery, medication and radiotherapy. The rationale for deciding the treatment are many but include the aggressiveness of the tumour. The aetiologies of sporadic pituitary adenomas are not fully understood. However, several causes have been identified resulting in specific familial phenotypes like multiple endocrine neoplasia type I (MEN1). MEN1 is related to mutations in the MEN1 gene, a tumour suppressor gene localized on chromosome 11q13 and which encodes menin, a 610 amino acid protein. During the last years, an evidence progressively emerged that MEN1-related adenomas were more aggressive and less responsive to therapy than their sporadic counterparts. In this article, we review the differences between sporadic and MEN1-related adenomas and suggest specific ways of treatment and follow-up for MEN1-related tumours. [less ▲]

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See detailModeling of Thin Insulating Layers with Dual 3-D Magnetodynamic Formulations
Dular, Patrick ULg; Geuzaine, Christophe ULg

in IEEE Transactions on Magnetics (2003), 39(3), 1139--1142

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See detailRelevance of bone mineral density, bone quality and falls in reduction of vertebral and non-vertebral fractures.
Hanssens, L.; Reginster, Jean-Yves ULg

in Journal of musculoskeletal & neuronal interactions (2003), 3(3), 189-93

All epidemiological studies conclude that without prompt, concerted and well-designed prevention programs, the increasing cost related to osteoporotic fractures will become an unbearable burden for the ... [more ▼]

All epidemiological studies conclude that without prompt, concerted and well-designed prevention programs, the increasing cost related to osteoporotic fractures will become an unbearable burden for the community within the next fifteen years. However, the most effective way of setting up such preventive strategies is not yet unequivocally defined. Low bone mass and microarchitectural damage of bone tissue may account for a large part of the epidemiology of vertebral fractures. Extraskeletal determinants, including low muscle strength, poor balance and gait, all resulting in an increased propensity to fall, also play a major role in the occurrence of hip fracture. Depending on the localization of the fractures, the relative importance of skeletal and extraskeletal risk factors can significantly differ. For prevention of vertebral fractures, drugs affecting bone mass and skeletal architecture may provide a substantial benefit while hip fracture prevention will be more successfully targeted by multi-faceted strategies concentrating not only on the skeletal dimension of the fracture but also aiming, either pharmacologically or through multi-intervention programs, at a reduction in the incidence and in the consequences of falls in the elderly. [less ▲]

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See detailIntroduction
Jacquemain, Marc ULg; Verjans, Pierre ULg

in Fédéralisme - Régionalisme (2003), 2002-2003(n° spécial « Mobilité et identités dans l’Eurégio Meuse-Rhin »), 3-11

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See detailCharacterization of hyperporous polyurethane-based gels by non-intrusive mercury porosimetry
Pirard, René ULg; Rigacci, Arnaud; Marechal, Jacqueline ULg et al

in Polymer (2003), 44(17), 4881-4887

Evaporative drying of polyurethane-based gels produces xerogels. Supercritical drying after replacement of interstitial liquid by supercritical CO2 produces aerogels. SEM micrographs show that both ... [more ▼]

Evaporative drying of polyurethane-based gels produces xerogels. Supercritical drying after replacement of interstitial liquid by supercritical CO2 produces aerogels. SEM micrographs show that both materials are made up of small size particles gathered up in filament-shaped, strongly cross-linked aggregates. Density measurements show that they both have a large pore volume. When submitted to mercury porosimetry, the behavior of these materials is similar to that of inorganic aerogels, as previously observed. Mercury does not penetrate the pore network, but the whole material is densified. The usual Washburn equation cannot be used to analyze the mercury porosimetry. A well-suited equation based on a buckling model of filament-shaped aggregates has been developed in order to determine the pore volume distribution of mineral dried gels. This equation is also valid for analyzing the texture of organic hyperporous materials like polyurethane dried nanoporous gel. (C) 2003 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailPiracetam Inhibits The Lipid-Destabilising Effect Of The Amyloid Peptide A Beta C-Terminal Fragment
Mingeot-Leclercq, Mp.; Lins, Laurence ULg; Bensliman, M. et al

in Biochimica et Biophysica Acta-Biomembranes (2003), 1609(1), 28-38

Amyloid peptide (Abeta) is a 40/42-residue proteolytic fragment of a precursor protein (APP), implicated in the pathogenesis of Alzheimer's disease. The hypothesis that interactions between Abeta ... [more ▼]

Amyloid peptide (Abeta) is a 40/42-residue proteolytic fragment of a precursor protein (APP), implicated in the pathogenesis of Alzheimer's disease. The hypothesis that interactions between Abeta aggregates and neuronal membranes play an important role in toxicity has gained some acceptance. Previously, we showed that the C-terminal domain (e.g. amino acids 29-42) of Abeta induces membrane permeabilisation and fusion, an effect which is related to the appearance of non-bilayer structures. Conformational studies showed that this peptide has properties similar to those of the fusion peptide of viral proteins i.e. a tilted penetration into membranes. Since piracetam interacts with lipids and has beneficial effects on several symptoms of Alzheimer's disease, we investigated in model membranes the ability of piracetam to hinder the destabilising effect of the Abeta 29-42 peptide. Using fluorescence studies and 31P and 2H NMR spectroscopy, we have shown that piracetam was able to significantly decrease the fusogenic and destabilising effect of Abeta 29-42, in a concentration-dependent manner. While the peptide induced lipid disorganisation and subsequent negative curvature at the membrane-water interface, the conformational analysis showed that piracetam, when preincubated with lipids, coats the phospholipid headgroups. Calculations suggest that this prevents appearance of the peptide-induced curvature. In addition, insertion of molecules with an inverted cone shape, like piracetam, into the outer membrane leaflet should make the formation of such structures energetically less favourable and therefore decrease the likelihood of membrane fusion. [less ▲]

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See detailNullité et réduction, note sous Rb. Gent, 4 février 2002
Biquet, Christine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailL’idole brisée : la droite belge francophone et la crise morale de la France (1934-1938)
Lanneau, Catherine ULg

in Journal of Belgian History = Revue Belge d'Histoire Contemporaine = Belgisch Tijdschrift voor Nieuwste Geschiedenis (2003), XXXIII(1-2), 177-214

The French-speaking right wing in Belgium has always granted a paramount place to France in its ideological cosmography. The concept of everlasting France, of her “mission”, of the part she could play on ... [more ▼]

The French-speaking right wing in Belgium has always granted a paramount place to France in its ideological cosmography. The concept of everlasting France, of her “mission”, of the part she could play on the international scene are topics wondered about constantly in intellectual and middle-class circles. The thirties and mostly the Popular Front era provide the Conservatives with a splendid opportunity to describe the future of their cultural icon with awe: the more the international context is threatening, the more France seems to have become fragile, isolated and going down the slope. Using the news given by the national papers or the widely circulated Parisian press, right-wing Belgians brood, of course, about the eclipse of France’s might, but point chiefly to the moral crisis as its cause. Very often they feel some nostalgia for the “Ancien Régime” and see the origin of the worrying current phenomenon in the hated French Revolution. Lot of factors are intertwined in the definition of the moral decay, but some are particularly highlighted. France is accused to be invaded by foreigners (their Jewish origins and Marxist creeds being stressed); Free-Masonry has a bad influence, as well as laic teaching, perverting youth by its pacifist and internationalist leanings. The degeneration of the religious spirit is lamented on account of its influence on the birth rate: the “Elder Daughter of the Church” gets emptier and emptier, whereas the populations of Fascist Italy and Nazi Germany are blooming. Opposition to parliamentary system is to the fore, as the politico-financial scandals, the governmental instability, the disreputable ways of the politicians themselves contribute all to the idea of the moral crisis. A cultural decline is parallel, with a loss of spirituality in the French society, engulfed in materialism and coarseness. Their stinging attacks, their bombastic style show how deeply rooted is the “decay of France” thesis among Belgian Conservatives. Beyond the French case, they fear a possible contamination of Belgium and the disappearance of their own traditional but vanishing values. Their fears and frights have certainly played a part in the 1936 turn-around towards the so-called Belgian “politique d’indépendance” in foreign affairs. [less ▲]

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See detailLoi du 2 août 2002 concernant la lutte contre le retard de paiement dans les transactions commerciales
Decharneux, Joëlle ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2003)

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See detailLe complexe Chrysoperla carnea en Belgique (Neuroptera : Chrysopidae)
Bozsik, Andras; Mignon, Jacques ULg; Gaspar, Charles

in Notes Fauniques de Gembloux (2003), 50

De 1997 à 2002, près de 4000 Chrysoperla carnea sensu lato furent collectées dans quinze localités de Belgique, principalement dans la ville de Gembloux (Province de Namur). Le fauchage de la végétation à ... [more ▼]

De 1997 à 2002, près de 4000 Chrysoperla carnea sensu lato furent collectées dans quinze localités de Belgique, principalement dans la ville de Gembloux (Province de Namur). Le fauchage de la végétation à l’aide d’un filet représente le principal mode d’échantillonnage. Les individus capturés furent identifiés sur base des descriptions de Thierry et al. (1992), Duelli (1995, 1999 communication personnelle), ainsi que par comparaison, soit avec différents types morphologiques (de D. Thierry), soit à des individus identifiés sur base de leurs chants (par P. Duelli). Chrysoperla kolthoffi sensu Cloupeau (Ch.c.c.4. ou « motorboat » sensu Henry) constitue le taxon le plus représenté dans les différentes localités. Chrysoperla carnea sensu Cloupeau (« low motorboat » sensu Henry) est également souvent rencontrée abondamment, principalement en automne. Seule Chrysoperla lucasina Lacroix est observée plus rarement chaque année et dans chaque lieu. La fréquence saisonnière de Ch. carnea s.C. est variable. Ainsi, elle est relativement faible en été et elle augmente progressivement au cours de l’automne. A cette période, les proportions de Ch. kolthoffi diminuent tandis que le taux de Ch. lucasina reste stable. [less ▲]

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See detailFronts and mesoscale variability in the southern Indian Ocean as inferred from the TOPEX/POSEIDON and ERS-2 altimetry data
Kostianoy, Andrey G.; Ginzburg, Anna I.; Lebedev, Sergey Anatolievich et al

in Oceanology (2003), 43(5, SEP-OCT), 632-642

Charts of sea level anomalies (SLA) based on the combined altimetry data from the TOPEX/POSEIDON and ERS-2 satellites, as well as the corresponding charts of the sea surface dynamic heights (constructed ... [more ▼]

Charts of sea level anomalies (SLA) based on the combined altimetry data from the TOPEX/POSEIDON and ERS-2 satellites, as well as the corresponding charts of the sea surface dynamic heights (constructed by the superposition of SLA distributions over the climatic dynamic topography) and the temperature gradients at the ocean surface on the basis of the satellite Multi-Channel Sea Surface Temperature (MCSST) data, were used to study the mesoscale variability related to the fronts in the Southern Indian Ocean (30degrees-60degrees S, 20degrees-150degrees E). An analysis of these three types of satellite information for the central weeks of each month during the period from 1997 to 1999 allowed us to distinguish zones of enhanced meandering (eddy formation) within the basin under study, as well as the contributions of individual fronts and their interaction to the regional mesoscale variability. The problems of the correlation between the intensity of mesoscale variability and peculiarities of the local bottom topography and seasonal/interannual variability of mesoscale dynamics are addressed. [less ▲]

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See detailFeasibility and reproducibility of off-line tissue Doppler measurement of regional myocardial function during dobutamine stress echocardiography.
Fraser, A. G.; Payne, N.; Madler, C. F. et al

in European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology (2003), 4(1), 43-53

AIMS: Off-line post-processing of colour tissue Doppler from digital loops may allow objective quantification of dobutamine stress echocardiography. We assessed the reproducibility of off-line ... [more ▼]

AIMS: Off-line post-processing of colour tissue Doppler from digital loops may allow objective quantification of dobutamine stress echocardiography. We assessed the reproducibility of off-line measurements of regional myocardial velocities. METHODS AND RESULTS: Nine observers analysed 10 studies, each making 2400 observations. Coefficients of variation in basal segments from apical windows, at rest and maximal stress, were 9-14% and 11-18% for peak systolic velocity, 16-18% and 17-19% for time-to-peak systolic velocity, 9-17% and 18-24% for systolic velocity time integral, and 18-23% and 21-27% for systolic acceleration. Coefficients of variation for diastolic velocities in basal segments at rest were 11-40%. Coefficients of variation for peak systolic velocity were 10-24% at rest and 14-28% at peak in mid segments, and 19-53% and 29-69% in apical segments. From parasternal windows coefficients of variation for peak systolic velocity were 14-16% in basal posterior, and 19-29% in mid-anterior segments. High variability makes measurement unreliable in apical and basal anterior septal segments. The feasibility of obtaining traces was tested in 92 subjects, and >90% in all basal and mid segments apart from the anterior septum. CONCLUSION: Quantification of myocardial functional reserve by off-line analysis of colour tissue Doppler acquired during dobutamine stress is feasible and reproducible in 11 segments of the left ventricle. The most reliable measurements are systolic velocities of longitudinal motion in basal segments. [less ▲]

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See detailFormation Of Plant Cuticle: Evidence For The Occurrence Of The Peroxygenase Pathway
Lequeu, J.; Fauconnier, Marie-Laure ULg; Chammai, A. et al

in Plant Journal (The) (2003), 36(2),

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See detailDetuning effects on the mazer
Martin, John ULg; Bastin, Thierry ULg

in Physicalia Magazine (2003), 25

A short review of the theoretical studies of the cold atom micromaser (mazer) is presented. Existing models are then improved by considering more general working conditions. Especially, the mazer physics ... [more ▼]

A short review of the theoretical studies of the cold atom micromaser (mazer) is presented. Existing models are then improved by considering more general working conditions. Especially, the mazer physics is investigated in the situation where a detuning between the cavity mode and the atomic transition frequency is present. Interesting new effects are pointed out. Especially, it is shown that the cavity may slow down or speed up the atoms according to the sign of the detuning and that the induced emission process may be completely blocked by use of a positive detuning. The transmission probability of ultracold atoms through a micromaser is also studied and we generalize previous results established in the resonant case. In particular, it is shown that the velocity selection of cold atoms passing through the micromaser can be very easily tuned and enhanced using a nonresonant field inside the cavity. [less ▲]

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See detailLes teignes du cuir chevelu d'ici et d'ailleurs. Quand la prévention est à géographie variable.
Arrese Estrada, Jorge ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2003), 58(6), 388-91

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new ... [more ▼]

Few diseases exhibit such regional variability in their epidemiology, even in an area as limited as Belgium, as tinea capitis. Thus, anthropophilic tinea capitis is highly predominant in areas where new immigrants from Black Africa and North Africa have settled. By contrast, zoophilic tinea capitis is found largely in areas where the cat population is infected. Kerion often affects professions in which contact with infected livestock is involved. Prevention of tinea capitis thus has distinct regional features. Treatment, on the other hand, has a universal basis. [less ▲]

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See detailLarge phosphorus hyperfine coupling as a sensitive tool for studying molecular dynamics : ESR and Molecular Mechanics studies of ring interconversion in cis-2,5-diphosphoryl-2,5-dimethyl-pyrrolidinoxyl radical
Rockenbauer, Antal; Gaudel-Siri, Anouk; Siri, Didier et al

in Journal of Physical Chemistry A (2003), 107(19), 3851-3857

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was ... [more ▼]

ESR spectra of cis- and trans-â-diphosphorylated pyrrolidine-N-oxyl radicals, c-1 and t-1, were studied in liquid and frozen solution. The expected 1:2:1 triplet (aP (2)) of the 1:1:1 triplet (aN) was observed for t-1; however, for c-1, the inner lines of the 1:2:1 triplet showed a dramatic broadening characteristic of chemical exchange between two equivalent conformations. Owing to the large difference in the hyperfine splitting constants (hfsc) of the exchanging phosphorus (¢aP 21 G), the coalescence temperature was unusually high (193 K, in n-pentane), and the potential barrier for ring interconversion (10.5 kJ mol-1) was easily obtained from the temperature dependence of the exchange rate. This value was in very good agreement with the value obtained for an empirical pseudorotational potential (11 kJ mol-1) that was adjusted to fit the temperature dependence of the phosphorus hfsc. For c-1, molecular mechanics calculations gave similar characteristics for the pseudorotational potential and indicated the existence of two identical minima with distorted geometries lying between 3T4 and 3E or 4T3 and E3. For t-1, only the 3T4 conformer was found to be significantly populated. Frozen solution spectra showed that the phosphorus hfsc anisotropy is higher when the C-P bond is pseudoaxial; this result can be explained by a geometry-dependent delocalization of the unpaired electron into the phosphorus 3p orbitals. [less ▲]

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See detailInsertion Of X-Ray Structures Of Proteins In Membranes
Basyn, F.; Spies, B.; Bouffioux, O. et al

in Journal of Molecular Graphics & Modelling (2003), 22(1), 11-21

Few structures of membrane proteins are known and their relationships with the membrane are unclear. In a previous report, 20 X-ray structures of transmembrane proteins were analyzed in silico for their ... [more ▼]

Few structures of membrane proteins are known and their relationships with the membrane are unclear. In a previous report, 20 X-ray structures of transmembrane proteins were analyzed in silico for their orientation in a 36A-thick membrane [J. Mol. Graph. Model. 20 (2001) 235]. In this paper, we use the same approach to analyze how the insertion of the X-ray structures varies with the bilayer thickness. The protein structures are kept constant and, at each membrane thickness, the protein is allowed to tilt and rotate in order to accommodate at their best. The conditions are said to be optimal when the energy of insertion is minimal. The results show that most helix bundles require thicker membranes than porin barrels. Moreover, in a few instances, the ideal membrane thickness is unrealistic with respect to natural membranes supporting that the X-ray structure requires adaptation to stabilize in membrane. For instance, the squalene cyclase could adapt by bending the side chains of its ring of lysine and arginine in order to increase the hydrophobic surface in contact with membranes. We analyzed the distribution of amino acids in the water, interface and acyl chain layers of the membrane and compared with the literature. [less ▲]

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See detailUn incunable de l'archevêque François Buisseret (1549-1615) : Réserve Précieuse de la Bibliothèque royale à Bruxelles, Inc B 1277
Adam, Renaud ULg

in Annales de la Société Archéologique de Namur (2003), 77

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See detailFactor-XIIIa-positive dendrocytes in drug-induced toxic epidermal necrolysis (Lyell's syndrome): paradoxical activation in skin and rarefaction in lymph nodes.
Paquet, Philippe ULg; Quatresooz, Pascale ULg; Pierard, Gérald ULg

in Dermatology : International Journal for Clinical & Investigative Dermatology (2003), 206(4), 374-8

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell ... [more ▼]

BACKGROUND: Drug-induced toxic epidermal necrolysis (TEN) is a rare life-threatening disease characterized by the extensive destruction of the epidermis contrasting with the discreteness of lymphoid cell infiltration. The precise pathomechanism of the disease remains unclear. METHODS: Skin specimens and peripheral and thoracic lymph nodes (LNs) were collected from 2 TEN patients. They were examined by conventional histology and immunohistochemistry using antibodies directed to factor XIIIa (dermal dendrocytes), CD1a (Langerhans cells), CD15 (granulocytes), CD20 (B lymphocytes), CD45RO (activated T lymphocytes), CD68 (macrophages) and the proliferation marker Ki-67. LNs from patients with mycosis fungoides, from subjects dead from acute cardiac failure or traumatic injuries, as well as metastasis-free sentinel LNs of cutaneous melanoma served as positive and negative controls. RESULTS: TEN LNs showed absence of germinal centers but a moderate hyperplasia of the paracortical T cell zone. Immunohistochemistry did not reveal any distinctive aspect in LN cellular densities between TEN and other control conditions except for the factor-XIIIa+ dendritic cells which were dramatically reduced in numbers in TEN LNs. This rarefaction in LNs contrasted with the great number of these cells in the skin of the same patients. CONCLUSION: The structure of TEN LNs rules out the involvement of an antibody-mediated response. As dendritic factor-XIIIa+ cells are involved in most cutaneous T-cell-mediated responses, their depletion in TEN LNs could explain the sparse lymphoid cell infiltrate in lesional TEN skin. [less ▲]

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See detailUn acte de mécénat d'Aubert Le Mire (1573-1640) en faveur des Dominicains de Bruxelles
Adam, Renaud ULg

in Revue du Cercle d'Histoire de Bruxelles et Extensions (2003), 79

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See detailWithin-herd effects of age at test day and lactation stage on test-day yields
Bormann, J.; Wiggans, G. R.; Druet, Tom ULg et al

in Journal of Dairy Science (2003), 86(11), 3765-3774

Variance ratios were estimated for random within-herd effects of age at test day and lactation stage, on test-day yield and somatic cell score to determine whether including these effects would improve ... [more ▼]

Variance ratios were estimated for random within-herd effects of age at test day and lactation stage, on test-day yield and somatic cell score to determine whether including these effects would improve the accuracy of estimation. Test-day data starting with 1990 calvings for the entire US Jersey population and Holsteins from California, Pennsylvania, Wisconsin, and Texas were analyzed. Test-day yields were adjusted for across-herd effects using solutions from a regional analysis. Estimates of the relative variance ( fraction of total variance) due to within-herd age effects were small, indicating that regional adjustments for age were adequate. The relative variances for within-herd lactation stage were large enough to indicate that accuracy of genetic evaluations could be improved by including herd stage effects in the model for milk, fat, and protein, but not for somatic cell score. Because the within-herd lactation stage effect is assumed to be random, the effect is regressed toward the regional effects for small herds, but in large herds, lactation curves become herd specific. Model comparisons demonstrated the greater explanatory power of the model with a within-herd-stage effect as prediction error standard deviations were greater for the model without this effect. The benefit of the within-herd-stage effects was confirmed in a random regression model by comparing variance components from models with and without random within-herd regressions and through log-likelihood ratio tests. [less ▲]

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See detailFirst-principles calculation of the band offset at BaO/BaTiO3 and SrO/SrTiO3 interfaces
Junquera, J.; Zimmer, M.; Ordejon, P. et al

in Physical Review. B, Condensed Matter and Materials Physics (2003), 67

We report first-principles density-functional pseudopotential calculations on the atomic structures, electronic properties, and band offsets of BaO/BaTiO3 and SrO/SrTiO3 nanosized heterojunctions grown on ... [more ▼]

We report first-principles density-functional pseudopotential calculations on the atomic structures, electronic properties, and band offsets of BaO/BaTiO3 and SrO/SrTiO3 nanosized heterojunctions grown on top of a silicon substrate. The density of states at the junction does not reveal any electronic induced interface states. A dominant perovskite character is found at the interface layer. The tunability of the band offset with the strain conditions imposed by the substrate is studied. Using previously reported theoretical data available for Si/SrO, Si/BaO, SrTiO3/Pt, and BaTiO3/SrRuO3 interfaces we extrapolate the band alignments along two gate stacks of technological interest: Si/SrO/SrTiO3/Pt and Si/BaO/BaTiO3/SrRuO3 heterostructures. [less ▲]

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See detailL'etude clinique du mois. L'etude Steno-2: plaidoyer pour une prise en charge globale et intensive du patient diabetique de type 2.
Scheen, André ULg; Estrella, F.

in Revue Médicale de Liège (2003), 58(2), 109-11

Cardiovascular morbidity is a major burden in patients with type 2 diabetes. The Steno-2 Study compared the effect of a targeted, intensified, multifactorial intervention (n = 80) with that of a ... [more ▼]

Cardiovascular morbidity is a major burden in patients with type 2 diabetes. The Steno-2 Study compared the effect of a targeted, intensified, multifactorial intervention (n = 80) with that of a conventional treatment (n = 80) on modifiable risk factors for cardiovascular disease in patients with type 2 diabetes and microalbuminuria. After a mean follow-up of 7.8 years, the risk of cardiovascular events was reduced by 53% in the intensive group, and the risk of microvascular events (nephropathy, retinopathy, autonomic neuropathy) by 58-63%. Thus, a target-driven, long-term, intensified intervention aimed at multiple risk factors should be recommended in patients with type 2 diabetes and microalbuminuria. [less ▲]

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See detailImbalance between lipoxin A(4) and leukotriene B-4 in chronic mastitis-affected cows
Boutet, Philippe ULg; Bureau, Fabrice ULg; Degand, Guy ULg et al

in Journal of Dairy Science (2003), 86(11), 3430-3439

Persistent accumulation of inflammatory cells in the udder, with neutrophils being the predominant cell type, is a characteristic feature of chronic mastitis in dairy cows. Leukotriene (LT) B-4 is a ... [more ▼]

Persistent accumulation of inflammatory cells in the udder, with neutrophils being the predominant cell type, is a characteristic feature of chronic mastitis in dairy cows. Leukotriene (LT) B-4 is a potent chemotactic agent, known to induce recruitment and accumulation of neutrophils in the bovine mammary gland. The LTB4-stimulated neutrophil functional responses are closely opposed by lipoxin (LX) A(4), which promotes the resolution of inflammation. We thus hypothesized that the chronic inflammation of the udder could be associated with an unfavorable ratio between these two eicosanoids and that the persistence of neutrophil accumulation could be due to an increase in LTB4 synthesis and/or an impaired LXA(4) production. In an attempt to verify this hypothesis, we first measured LXA(4), LTB4, and their ratio in the milk of healthy and acute and chronic mastitis-affected quarters. Next, we studied the relationships between these variables and the degree of udder inflammation as assessed by somatic cell count measurement. The LTB4 concentration was low in healthy quarters, drastically increased in acute mastitis, and reached intermediate levels in chronic mastitis-affected quarters. However, whereas LXA(4) concentration was highly increased in acute mastitis, healthy and chronic quarters had similarly low values. The LXA(4):LTB4 ratio was thus significantly lower in chronic mastitis-affected cows. The LTB4 concentrations measured in chronic quarters were highly correlated to somatic cell count and to milk neutrophil and macrophage numbers. A weaker correlation was observed between LXA(4) and these variables. For both eicosanoids, the highest correlation was observed with the number of neutrophils. These results show the existence of an LXA(4):LTB4 imbalance in chronic mastitis-affected cows because of low LXA(4) concentrations. Further studies are needed to determine whether administration of LX or stable analogs could have therapeutic potential in the control of chronic bovine mastitis. [less ▲]

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See detailTierce décision obligatoire et violation d'une règle de procédure conventionnellement arrêtée par les parties
Caprasse, Olivier ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2003)

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See detailMarine mammals from the southern North Sea: feeding ecology data from delta C-13 and delta N-15 measurements
Das, Krishna ULg; Lepoint, Gilles ULg; Leroy, Yann et al

in Marine Ecology. Progress Series (2003), 263

The harbour porpoise Phocoena phocoena, grey seal Halichoerus grypus, harbour seal Phoca vitulina and white-beaked dolphin Lagenorhynchus albirostris are regularly found stranded along southern North Sea ... [more ▼]

The harbour porpoise Phocoena phocoena, grey seal Halichoerus grypus, harbour seal Phoca vitulina and white-beaked dolphin Lagenorhynchus albirostris are regularly found stranded along southern North Sea coasts. Occasionally, offshore species such as the fin whale Balaenoptera physalus, the white-sided dolphin L. acutus and the sperm whale Physeter macrocephalus are also found stranded. In order to trace their diet, we measured delta(13)C and delta(15)N in their muscles as well as in 49 invertebrate and fish species collected from the southern North Sea. The delta(15)N data indicate that the harbour seal, grey seal and white-beaked dolphin occupy the highest trophic position, along with ichtyophageous fishes such as the cod Gadus morhua (mean muscle values of 18.7, 17.9, 18.8 and 19.2parts per thousand respectively). The harbour porpoise occupies a slightly lower trophic position (mean delta(15)N value of 16.2parts per thousand), reflecting a higher amount of zooplanktivorous fishes in its diet (mean delta(15)N of 14.7parts per thousand); 2 suckling harbour porpoises displayed a significant delta(15)N enrichment of 2.2parts per thousand compared to adult females. Adult females are delta(15)N-enriched compared to adult male harbour porpoises. Fin whales, sperm whales and white-sided dolphins are C-13-depleted compared to southern North Sea particulate organic matter and species, suggesting that despite regular sightings, they do not feed within the southern North Sea area. [less ▲]

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See detailModeling lactation curves and estimation of genetic parameters for first lactation test-day records of French Holstein cows.
Druet, Tom ULg; Jaffrezic, F.; Boichard, D. et al

in Journal of Dairy Science (2003), 86(7), 2480-90

Several functions were used to model the fixed part of the lactation curve and genetic parameters of milk test-day records to estimate using French Holstein data. Parametric curves (Legendre polynomials ... [more ▼]

Several functions were used to model the fixed part of the lactation curve and genetic parameters of milk test-day records to estimate using French Holstein data. Parametric curves (Legendre polynomials, Ali-Schaeffer curve, Wilmink curve), fixed classes curves (5-d classes), and regression splines were tested. The latter were appealing because they adjusted the data well, were relatively insensitive to outliers, were flexible, and resulted in smooth curves without requiring the estimation of a large number of parameters. Genetic parameters were estimated with an Average Information REML algorithm where the average information matrix and the first derivatives of the likelihood functions were pooled over 10 samples. This approach made it possible to handle larger data sets. The residual variance was modeled as a quadratic function of days in milk. Quartic Legendre polynomials were used to estimate (co)variances of random effects. The estimates were within the range of most other studies. The greatest genetic variance was in the middle of the lactation while residual and permanent environmental variances mostly decreased during the lactation. The resulting heritability ranged from 0.15 to 0.40. The genetic correlation between the extreme parts of the lactation was 0.35 but genetic correlations were higher than 0.90 for a large part of the lactation. The use of the pooling approach resulted in smaller standard errors for the genetic parameters when compared to those obtained with a single sample. [less ▲]

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See detailCompte rendu de l'ouvrage de S. Dawans : Le spectre de la honte
Cormann, Grégory ULg

in Archives de Philosophie (2003), 66(2), 340-342

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See detailA arbitragem e os grupos de sociedades
Caprasse, Olivier ULg

in Revista de Direito Bancario, do Mercado de Capitais e da Arbitragem (2003)

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See detailDevelopment Of Real-Time Pcr For The Rapid Detection Of Episomal Banana Streak Virus (Bsv)
Delanoy, Martine; Salmon, Marc ULg; Kummert, Jean et al

in Plant Disease (2003), 87(1), 33-38

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See detailLeclercq Suzanne.
Streel, Maurice ULg; Fairon-Demaret, M

in Académie Royale des sciences lettres et beaux arts de Belgique/ Nouvelle biographie nationale (2003), 7

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See detailThe thymic insulin-like growth factor axis: Involvement in physiology and disease
Geenen, Vincent ULg

in Hormone & Metabolic Research (2003), 35(11-12, Nov-Dec), 656-663

A repertoire of neuroendocrine-related genes is transcribed in the non-lymphoid compartment of the thymus, transposing the dual physiological role of this organ at the molecular level in T-cell ... [more ▼]

A repertoire of neuroendocrine-related genes is transcribed in the non-lymphoid compartment of the thymus, transposing the dual physiological role of this organ at the molecular level in T-cell development towards the establishment of central T-cell self-tolerance. The "neuroendocrine self" has been defined as a series of antigen sequences processed from precursors predominantly expressed in the thymus and first encountered by differentiating T-lymphocytes in their early life. All the members of the insulin gene family are expressed in the thymus according to a precise hierarchy and cellular topography, whereby IGF-II (epithelium of the subcapsular cortex and medulla) exceeds IGF-I (macrophages), which in turn far exceeds INS (rare subsets of medullary epithelial cells). This hierarchy in the degree of their respective thymic expression explains why IGF-II is more tolerated than IGF-I, and much more so than insulin. Evidence has been found for significant regulatory/tolerogenic properties in the IGF-II B:11-25 sequence after analysis of the cytokine secretion profile in peripheral blood mononuclear cells isolated from ten DQ8+ type 1 diabetic adolescents. In the thymus, IGF ligands and receptors also intervene in the control of T-cell proliferation and differentiation. Here, we also discuss how a disturbance in the intrathymic IGF-mediated signaling could contribute to the pathogenesis of T-cell leukemia. [less ▲]

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See detailStructural Optimization of the Blanc Pain Flood Control Gate
Rigo, Philippe ULg; Vercruysse, S.; Sarghiuta, R.

in Bulletin scientifique de l'UTCB (2003)

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See detailNecrotizing varicella zoster virus folliculitis.
Nikkels, Arjen ULg; Pierard, Gérald ULg

in European Journal of Dermatology (2003), 13(6), 587-9

Although the usual clinical features of the varicella zoster virus (VZV)-induced lesions are readily recognized, the same virus is also responsible for a series of atypical lesions. A patient is presented ... [more ▼]

Although the usual clinical features of the varicella zoster virus (VZV)-induced lesions are readily recognized, the same virus is also responsible for a series of atypical lesions. A patient is presented with a single large infiltrated plaque on the abdomen. Although histology showed a necrotizing folliculitis surrounded by a dense perifollicular inflammatory infiltrate, the clinical presentation was not suggestive of folliculitis. Subtle cyto-histological clues for viral infection were suggested. Immunohistochemistry revealed the presence of VZV in the remnants of the follicular structures. This report underlines one of the protean clinical presentations of VZV skin infections and highlights the discreteness of typical VZV-related cyto-histological alterations. Complementary VZV identification methods such as immunohistochemistry, are helpful in order to increase the diagnostic accuracy of unusual VZV lesions. [less ▲]

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See detailEnhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis.
Abushoffa, Adel M; Fillet, Marianne ULg; Servais, Anne-Catherine ULg et al

in Electrophoresis (2003), 24(3), 343-50

The enantiomeric separation of some nonsteroidal anti-inflammatory drugs (NSAIDs) was investigated in capillary electrophoresis (CE) using dual systems with mixtures of charged cyclodextrin (CD ... [more ▼]

The enantiomeric separation of some nonsteroidal anti-inflammatory drugs (NSAIDs) was investigated in capillary electrophoresis (CE) using dual systems with mixtures of charged cyclodextrin (CD) derivatives. A significant enhancement of selectivity and resolution could be achieved in the enantioseparation of these analytes in their uncharged form by the simultaneous addition of two oppositely charged CD derivatives to the background electrolyte. The combination of the single-isomer cationic CD, permethyl-6-monoamino-6-monodeoxy-beta-CD (PMMAbetaCD) and the single-isomer polyanionic CD, heptakis-6-sulfato-beta-cyclodextrin (HSbetaCD) in a pH 2.5 phosphoric acid-triethanolamine buffer, was designed and employed for the enantioseparation of profens. The improvement in selectivity and resolution can be attributed to the fact that the two CDs, which lead to independent and enantioselective complexation with the analyte enantiomers, have not only opposite effects on the electrophoretic mobility of these compounds but also opposite affinity patterns towards the enantiomers of these compounds. Binding constants for these enantiomers with each CD were determined using linear regression approach, in order to be able to predict the effect of the concentrations of the two CDs on enantiomeric selectivity and resolution in such dual systems. [less ▲]

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See detailDéveloppement de modèles prédictifs des proportions de duramen et d'écorce des espèces de mélèze cultivées en zones de basse altitude en Europe de l'Ouest (Larix kaempferi (Lambert) Carr., Larix decidua Miller et Larix eurolepis Henry).
Pauwels, D.; Lejeune, Philippe ULg; Paques, L. E. et al

in Annals of Forest Science : a Multidisciplinary and International Journal (2003), 60(3), 227-235

Predictive models for heartwood and bark proportions have been developed for Japanese larch (Larix kaempferi (Lambert) Carr.) planted in South of Belgium. These models have been tested to evaluate the way ... [more ▼]

Predictive models for heartwood and bark proportions have been developed for Japanese larch (Larix kaempferi (Lambert) Carr.) planted in South of Belgium. These models have been tested to evaluate the way of applying them to European larch (Larix decidua Miller) and hybrid larch (Larix eurolepis Henry) growing in west-European lowlands. For the heartwood proportion, independent variables selected are stand age and dbh. The model set up for Japanese larch has a R-square of 0.859. In average, European larch has lower heartwood proportion. With reference to bark proportion, selected independent variable is dbh. Residual variability is far more important for bark models (R-square of 0.456). European larch has, in average, higher bark proportion whereas hybrid larch has lower. An example of the application of these models in connection with a growth model is presented. It consists in an evaluation of the impact of dynamic silviculture on heartwood and bark proportion. [less ▲]

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See detailThe contribution of recollection and familiarity to recognition memory : A study of the effects of test format and aging
Bastin, Christine ULg; Van der Linden, Martial ULg

in Neuropsychology (2003), 17(1), 14-24

Whether the format of a recognition memory task influences the contribution of recollection and familiarity to performance is a matter of debate. The authors investigated this issue by comparing the ... [more ▼]

Whether the format of a recognition memory task influences the contribution of recollection and familiarity to performance is a matter of debate. The authors investigated this issue by comparing the performance of 64 young (mean age = 21.7 years; mean education = 14.5 years) and 62 older participants (mean age = 64.4 years; mean education = 14.2 years) on a yes–no and a forced-choice recognition task for unfamiliar faces using the remember– know–guess procedure. Familiarity contributed more to forced-choice than to yes–no performance. Moreover, older participants, who showed a decrease in recollection together with an increase in familiarity, performed better on the forced-choice task than on the yes–no task, whereas younger participants showed the opposite pattern. [less ▲]

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See detailL'image du mois. Hématome hépatique après une réanimation cardio-pulmonaire
Delanaye, Pierre ULg; De Fooz, Geoffroy; NCHIMI LONGANG, Alain ULg et al

in Revue Médicale de Liège (2003), 58(7-8, Jul-Aug), 463-464

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See detailCutaneous psammomatous melanotic schwannoma: non-recurrence with surgical excision.
Claessens, Nadine; Heymans, Olivier; Arrese Estrada, Jorge ULg et al

in American Journal of Clinical Dermatology (2003), 4(11), 799-802

BACKGROUND: Melanotic schwannoma is a pigmented nerve tumor that may be located in the skin and express local aggressivity. This tumor may occur singly. It may also be part of the Carney complex which ... [more ▼]

BACKGROUND: Melanotic schwannoma is a pigmented nerve tumor that may be located in the skin and express local aggressivity. This tumor may occur singly. It may also be part of the Carney complex which consists of various, but specific, tumors. OBJECTIVE: We report two cases of subcutaneous melanotic schwannoma localized on the trunk in two men aged 37 and 45 years. METHODS: Conventional histology and immunohistochemistry were performed. RESULTS: One melanotic schwannoma was associated with a cutaneous atypical myxoma and multiple melanocytic lesions, all being part of the Carney complex. The other case had no associated signs. In both cases, the melanotic schwannoma was completely excised and did not recur. CONCLUSION: Melanotic schwannoma is rare and curable by surgery. It must not be confused with malignant melanoma and other pigmented neoplasms. The Carney complex should be carefully ruled out. [less ▲]

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See detailLa transplantation d'ilots de Langerhans ou de cellules B: un pas vers la guerison du diabete?
Philips, Jean-Christophe ULg; Radermecker, Régis ULg; Scheen, André ULg

in Revue Médicale de Liège (2003), 58(2), 83-7

Diabetes mellitus places an enormous burden on patients, their relatives and the society. Current therapies do not provide sufficiently tight control of blood glucose to avoid diabetic complications. Some ... [more ▼]

Diabetes mellitus places an enormous burden on patients, their relatives and the society. Current therapies do not provide sufficiently tight control of blood glucose to avoid diabetic complications. Some recent developments try to restore normal glucose homeostasis. Research is islet and stem cell transplantation is developing rapidly and this article summarizes the new approaches that could cure and not simply treat diabetes in the future. [less ▲]

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See detailModelling eutrophication in mesotidal and macrotidal estuaries. The role of intertidal seaweeds.
Alvera Azcarate, Aïda ULg; Ferreira, Joao; Nunes, Joao

in Estuarine Coastal & Shelf Science (2003), 57

The role of intertidal seaweeds in the primary production of mesotidal and macrotidal estuaries has been examined by means of a model, applied to the Tagus Estuary (Portugal). Special attention was paid ... [more ▼]

The role of intertidal seaweeds in the primary production of mesotidal and macrotidal estuaries has been examined by means of a model, applied to the Tagus Estuary (Portugal). Special attention was paid to the description of the underwater light climate in intertidal areas, and to the importance of the formation of tidal pools. Two approaches were compared for the simulation of suspended particulate matter (SPM) in the pool areas, using three algal species. The use of an erosion–deposition approach to simulate the distribution of SPM in tidal pools gives an increase in net primary productivity per unit area of between 130 and 1300%, when compared to the more conventional approach where the suspended matter in the overlying water in intertidal areas is considered identical to that in the channels. The upscaled erosion–deposition model was applied to tidal pool areas and combined with the more conventional model for other intertidal areas. Results show that annual carbon fixation by intertidal seaweeds in the estuary exceeds 13,500 t C yr−1, and accounts for 21% of the total carbon fixed by all primary producers. The corresponding nitrogen removal by seaweeds corresponds to the annual nutrient loading of a population of 490,000 inhabitants. [less ▲]

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See detailEditorial. Vers le troisième départ du mélèze en Région wallonne
Hebert, Jacques ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2003), 7(1), 3-4

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See detailUltradispersity of diamond at the nanoscale
Raty, Jean-Yves ULg; Galli, G.

in Nature Materials (2003), 2(12), 792-795795

Nanometre-sized diamond has been found in meteorites, protoplanetary nebulae, and interstellar dusts, as well as in residues of detonation and in diamond films. Remarkably, the size distribution of ... [more ▼]

Nanometre-sized diamond has been found in meteorites, protoplanetary nebulae, and interstellar dusts, as well as in residues of detonation and in diamond films. Remarkably, the size distribution of diamond nanoparticles seems to be peaked around 2-5 nm, and to be largely independent of preparation conditions. We have carried out ab initio calculations of the stability of nanodiamond as a function of surface hydrogen coverage and of size. We have found that at about 3 nm, and for a broad range of pressures and temperatures, particles with bare, reconstructed surfaces become thermodynamically more stable than those with hydrogenated surfaces, thus preventing the formation of larger grains. Our findings provide an explanation of the size distribution of extraterrestrial and of terrestrial nanodiamond found in ultradispersed and ultracrystalline diamond films. They also provide an atomistic structural model of these films, based on the topology and structure of 2-3 nm diamond clusters consisting of a diamond core surrounded by a fullerene-like carbon network [less ▲]

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See detailChanging Patterns of Political Participation of Citizens of Immigrant Origin in the Brussels Capital Region. The October 2000 Elections
Martiniello, Marco ULg; Rea, Andrea; Jacobs, Dirk

in Journal of International Migration & Integration (2003), 3(2), 201-221

The October 2000 elections did constitute a landmark for the political participation of immigrant origin citizens in the Brussels Capital Region. There was a remarkable increase of elected Belgian ... [more ▼]

The October 2000 elections did constitute a landmark for the political participation of immigrant origin citizens in the Brussels Capital Region. There was a remarkable increase of elected Belgian politicians of non-EU–mainly Moroccan–origin. In this contribution we want to discuss the changing patterns of political participation of immigrant origin citizens in the Brussels Capital Region as seen in the most recent local elections. We contextualize the electoral success of Turkish and (mainly) Moroccan politicians and the poor involvement of EU citizens in the recent elections. To this purpose, we also discuss the political situation in the bilingual region of Brussels, Belgian citizenship law and regulations for political participation of foreign residents. [less ▲]

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See detailIn memoriam Roger Vigneron
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2003), L

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See detailComment je traite ... une hypoglycemie grave chez un patient diabetique.
Radermecker, Régis ULg; Philips, Jean-Christophe ULg; Scheen, André ULg

in Revue Médicale de Liège (2003), 58(3), 119-22

Severe hypoglycaemic episodes are defined as need of assistance and may progress to profound coma. They can occur in patients treated with insulin, generally for type 1 diabetes, or in patients receiving ... [more ▼]

Severe hypoglycaemic episodes are defined as need of assistance and may progress to profound coma. They can occur in patients treated with insulin, generally for type 1 diabetes, or in patients receiving sulphonylureas, for type 2 diabetes. Diagnosis is usually obvious, at least in insulin-treated patients, and requires an urgent intervention from the entourage. Such an intervention should comprise the oral administration of carbohydrates with high-glycaemic index if consciousness allows it or, if not, the injection of glucagon. When necessary, people should ask the help of a physician who will inject hypertonic glucose intravenously. Hypoglycaemic coma related to an absolute or relative excess of insulin should, in most cases, be treated at home. In contrast, a hypoglycaemic coma due to a too high dosage of sulphonylurea always requests a hospitalisation in order to carefully supervise the patient and to provide a prolonged intravenous infusion of glucose. It is mandatory that family or entourage members of any diabetic patient at risk to develop severe hypoglycaemia receive a specific education in order to promptly apply the best treatment capable of a rapid and safe recovery from hypoglycaemic coma. [less ▲]

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See detailnote sous arrêt du 23 octobre 2003, Van den Bergh Foods contre Commission
Petit, Nicolas ULg

in Revue du Droit de l'Union Européenne (2003)

résumé et analyse de l'affaire Volkswagen AG contre Commission, affaire C-338/00

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See detailModèle de croissance pour les plantations de mélèzes.
Pauwels, D.; Lejeune, Philippe ULg; Rondeux, Jacques ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2003), 7(2), 87-97

A distance independent tree growth model has been determined for pure and even-aged larch stands (Larix sp.) growing in Walloon Region (South Belgium). This model has been built from 2578 larches ... [more ▼]

A distance independent tree growth model has been determined for pure and even-aged larch stands (Larix sp.) growing in Walloon Region (South Belgium). This model has been built from 2578 larches (Japanese, European and Hybrid larches) in 99 stands. It enables to predict tree circumference increment from circumference, dominant height, basal area, age and site index of stands. Estimating increments of 1283 larches in 48 stands has been used to validate the model that gives unbiased estimates of the increments (mean error = -0.002 cm with standard deviation of 0.60 cm). The mean absolute error of estimates is 0.46 cm.year-1. The model has also been tested to predict the increment of larches in French experimental plots having very different silvicultural treatments. The residues of these estimations depend on the stand basal area: the lesser the stand basal area, the higher the residues of the estimation. A correction factor, linked to basal area through a Bailey and Clutter curve, has been introduced to extend the validity of the model to stands with a basal area lower than 12 m2.ha-1. This factor does not affect the increment estimations if the stand characteristics are close to mean value of the sample used to build the model (correction factor close to 1). The introduction in the model of competition indexes distance dependant or site qualitative variables does not significantly improve the growth model. [less ▲]

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See detailChronique de la 57ème Session de la SIHDA à Clermont-Ferrand (16-20 Septembre 2003)
Gerkens, Jean-François ULg

in Revue Internationale des Droits de l'Antiquité (2003), L

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See detailDesign and simulation of a solar dryer for agriculture products
Bennamoun, Lyes ULg; Belhamri, Azeddine

in Journal of Food Engineering (2003), 59(2-3),

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See detailSentence processing strategies in French-speaking children with SLI: a study of morphosyntactic cues
Maillart, Christelle ULg; Schelstraete, Marie-Anne

in Journal of Multilingual Communication Disorders (2003), 1

The sentence comprehension strategies used by children with speci®c language impairments (SLI) were examined within the framework of the Competition Model (Bates and MacWhinney, 1989). The experiment was ... [more ▼]

The sentence comprehension strategies used by children with speci®c language impairments (SLI) were examined within the framework of the Competition Model (Bates and MacWhinney, 1989). The experiment was a replication of Kail and Charvillat'experiment (1988) designed to investigate the use of different morphosyntactic cues (i.e. word order, clitic pronoun, verbal agreement) in sentence comprehension by children (4;6 ± 6;6) with normal language development. They found that French speaking children used mainly information on word order with a lesser reliance on the other cues (word order4clitic pronoun4verbal agreement). In the present study, the same experiment was replicated with 25 French speaking children with SLI. The results suggested that children with SLI had speci®c di culties in processing clitic pronouns, while verbal agreement could be processed (word order4verbal agreement4clitic pronoun). This pattern seems to be a speci®c strategy and not simply a delayed pro®le. In addition, our results were compatible with a theoretical account in terms of limitation in processing capacities. [less ▲]

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See detailRedefining the role of psr in beta-lactam resistance and cell autolysis of Enterococcus hirae.
Sapunaric, Frédéric ULg; Franssen, Christine; Stefanic, Patrick et al

in Journal of Bacteriology (2003), 185(20), 5925-35

The contribution of penicillin-binding protein 5 (PBP5) and the PBP5 synthesis repressor (Psr) to the beta-lactam resistance, growth, and cell autolysis of wild-type strain ATCC 9790 and resistant strain ... [more ▼]

The contribution of penicillin-binding protein 5 (PBP5) and the PBP5 synthesis repressor (Psr) to the beta-lactam resistance, growth, and cell autolysis of wild-type strain ATCC 9790 and resistant strain R40 of Enterococcus hirae was investigated by disruption or substitution of the corresponding pbp5 and psr genes by Campbell-type recombination. The resulting modifications were confirmed by hybridization and PCR. The low susceptibility of E. hirae to beta-lactams was confirmed to be largely dependent on the presence of PBP5. However, against all expectations, inactivation of psr in ATCC 9790 or complementation of R40 cells with psr did not modify the susceptibility to benzylpenicillin or the growth and cell autolysis rates. These results indicated that the psr gene does not seem to be involved in the regulation of PBP5 synthesis and consequently in beta-lactam resistance or in the regulation of cell autolysis in E. hirae. [less ▲]

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See detailProcédure de liquidation-partage
Leleu, Yves-Henri ULg

in Revue de Droit de l'ULB (2003)

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See detailThe core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo
Markine-Goriaynoff, N.; Georgin, J. P.; Goltz, M. et al

in Journal of Virology (2003), 77(3), 1784-1792

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To ... [more ▼]

The Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the Bo17 gene, we analyzed its distribution among BoHV-4 strains and determined the sequences of Bo17 from nine representative strains and of the C2GnT-M gene from six species of ruminants expected to encompass the group within which the gene acquisition occurred. Of 34 strains of BoHV-4, isolated from four different continents, all were found to contain the Bo17 gene. Phylogenetic analyses indicated that Bo17 was acquired from a recent ancestor of the African buffalo, implying that cattle subsequently acquired BoHV-4 by cross-species transmission. The rate of synonymous nucleotide substitution in Bo17 was estimated at 5 x 10(-8) to 6 x 10(-8) substitutions/site/year, consistent with previous estimates made under the assumption that herpesviruses have cospeciated with their hosts. The Bo17 gene acquisition was dated to around 1.5 million years ago. Bo17 sequences from BoHV-4 strains from African buffalo and from cattle formed two separate clades, estimated to have split about 700,000 years ago. Analysis of the ratio of nonsynonymous to synonymous nucleotide substitutions revealed a burst of amino acid replacements subsequent to the transfer of the cellular gene to the viral genome, followed by a return to a strong constraint on nonsynonymous changes during the divergence of contemporary BoHV-4 strains. The Bo17 gene represents the most recent of the known herpesvirus gene acquisitions and provides the best opportunity for learning more about this important process of viral evolution. [less ▲]

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See detailPara-Adrenal Adrenal Pseudocyst
Milicevic, Mladen ULg; Dondelinger, Robert ULg; Detry, Olivier ULg

in JBR-BTR : Journal Belge de Radiologie - Belgisch Tijdschrift voor Radiologie (2003), 86(3, May-Jun), 166-7

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See detailSelection of the most efficient wavelength bands for 'Jonagold' apple sorting
Kleynen, O.; Leemans, Vincent ULg; Destain, Marie-France ULg

in Postharvest Biology & Technology (2003), 30(3), 221-232

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system ... [more ▼]

This paper presents a method based on quadratic discriminant analysis to select the best filters for detecting a wide range of defects in 'Jonagold' apple fruit using a multi-spectral vision system. Reflectance spectra of damaged and sound tissue were recorded using a visible/NIR spectrometer. Analysed defects consisted of scald, hail damage (with and without skin perforation), limb rubs, russets, scab tissue, frost damage, rot, visible flesh damage and recent bruises. Camera filter effects were approximated by summing the reflectances of all the wavelengths within the filter bandwidth. Combinations of three and four filters were tested and evaluated for discriminating damaged tissues from healthy ones. If a three-filter combination appeared sufficient to detect most of the damaged tissue, a four-filter combination should be considered for the complete sorting automation of this bicolour apple variety. A fourth filter was necessary to quantify the ratio between the blush and ground colours. Regarding recent bruise defects which represented the major difficulty, an image segmentation algorithm based on local contrast variations can enhance their detection. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailInfluence Molecular Arrangement in Self-assembled Monolayers on Adhesion Forces Measured by Chemical Force Microscopy
Duwez, Anne-Sophie ULg; Jonas, Ulrich; Klein, Hubert

in Chemphyschem : A European Journal of Chemical Physics and Physical Chemistry (2003), 4

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See detailSkin-lightening products revisited.
Petit, Ludivine; Pierard, Gérald ULg

in International Journal of Cosmetic Science (2003), 25(4), 169-81

Skin colour typology depends on the amount and location of its chromophores. Among them, eumelanins derived from 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and 5,6-dihydroxyindole (DHI), and ... [more ▼]

Skin colour typology depends on the amount and location of its chromophores. Among them, eumelanins derived from 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and 5,6-dihydroxyindole (DHI), and phaeomelanins are of utmost importance. These biomolecules result from the multi-step enzymatic and non-enzymatic conversion of tyrosine into melanins. Pigmentation disorders are multiple and depend on alterations in the density in active melanocytes, and on specific abnormalities of any of the complex melanogenesis mechanisms. This review presents some of the main skin-lightening agents with respect to their mechanisms of action and side-effects. Some of the novel compounds may lead to new perspectives in the fields of dermatology and cosmetology. The methods commonly used to assess efficacy of skin-lightening products rely on in vitro models including cell-free enzymatic assays, melanocyte cultures and reconstructed epidermis bioassays. Animal models have little relevance. By contrast, human testing with the support of instrumental evaluations is the most informative. [less ▲]

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See detailInduction et synchronisation de l'oestrus par la PGF2alpha
Hanzen, Christian ULg; Boudry, B.; Drion, Pierre ULg

in Point Vétérinaire (2003), 34(236), 22-23

Hormonal management of reproduction uses treatments that regulate both luteal activity and follicular growth to achieve expulsion in the shortest period of an oocyte capable of being fertilised. Therefore ... [more ▼]

Hormonal management of reproduction uses treatments that regulate both luteal activity and follicular growth to achieve expulsion in the shortest period of an oocyte capable of being fertilised. Therefore, PgF2alpha has been the object of numerous trials either as sin e or repeated injections, alone or in association with other hormones such as gonadorelin. Systematic insemination is more difficult after a single injection because return to ea is variable. A single injection is better for the physiology of follicular growth than the corpus luteum. Use of a double injection of PgF2alpha improves the degree of synchronisation but doesn't affect the ovulation rate. [less ▲]

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See detailSensitivity analysis on ultimate strength of aluminium stiffened panels
Rigo, Philippe ULg; Sarghiuta, B.; Estefen, S. et al

in Marine Structures (2003)

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See detailEstimation of habitat quality based on plant community, and effects of isolation in a network of butterfly habitat patches
Sawchik, J.; Dufrêne, Marc ULg; Lebrun, Philippe

in Acta Oecologica (2003), 24(1), 25-33

Minimum viable site networks are crucial for many threatened species but their design is always a difficult procedure. The present study investigated methods to estimate habitat quality of patches, in an ... [more ▼]

Minimum viable site networks are crucial for many threatened species but their design is always a difficult procedure. The present study investigated methods to estimate habitat quality of patches, in an ecological network for five butterfly species (Brenthis ino, Clossiana selene, Lycaena helle, Lycaena hippothoe, Proclossiana eunomia) inhabiting wet meadows. Abundance predictions were performed on the basis of botanical relevés with a multiple-species approach combining canonical correspondence analysis and multiple regression. Models are defined on a reference site set and are evaluated on a test site set. All the fitted models predicted the abundance of the butterfly species considerably well (from 61 to 86% of the variation). We evaluated the potential consequences of isolation on local populations, by comparing predicted and observed abundance. It was expected that greater differences would be observed when sites were more isolated. On the test set, differences between predicted and observed abundance were largely correlated to site isolation for L. helle and P. eunomia. The most isolated sites had greater chances to be empty, even if they had high-quality habitat. Reciprocally, when the sites were less isolated, the abundance observed was always greater than predicted, seeming to confirm the role of rescue effects. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved. [less ▲]

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See detailElectromagnetic modes in dusty plasmas with charge and mass distributions
Verheest, F.; Cattaert, Tom ULg

in Physics of Plasmas (2003), 10(4), 956-962

Electromagnetic modes in dusty plasmas are studied for polydisperse dust grains with a distribution in charge and mass. Owing to the different charge and mass weightings of the velocities, there occurs an ... [more ▼]

Electromagnetic modes in dusty plasmas are studied for polydisperse dust grains with a distribution in charge and mass. Owing to the different charge and mass weightings of the velocities, there occurs an infinite chain of equations of motion, coupled through the magnetic part of the Lorentz force. Depending on the frequency and associated convergence regimes, one has to close the chain in ascending or in descending order. Both series together lead to the polydisperse dispersion law that is a generalization of monodisperse or size distributed dust. Power-law distributions typical for heliospheric plasmas are discussed as an application. (C) 2003 American Institute of Physics. [less ▲]

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See detailMR2001084,Advanced electromagnetism and vacuum physics, Cornille, Patrick
Rochus, Pierre ULg

in Mathematical Reviews [=MR] (2003)

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See detailInteraction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression.
Twizere, Jean-Claude ULg; Kruys, Veronique; Lefebvre, Laurent et al

in Journal of the National Cancer Institute (2003), 95(24), 1846-59

BACKGROUND: The Tax oncoproteins are transcriptional regulators of viral expression involved in pathogenesis induced by complex leukemogenic retroviruses (or delta-retroviruses, i.e., primate T-cell ... [more ▼]

BACKGROUND: The Tax oncoproteins are transcriptional regulators of viral expression involved in pathogenesis induced by complex leukemogenic retroviruses (or delta-retroviruses, i.e., primate T-cell leukemia viruses and bovine leukemia virus). To better understand the molecular pathways leading to cell transformation, we aimed to identify cellular proteins interacting with Tax. METHODS: We used a yeast two-hybrid system to identify interacting cellular proteins. Interactions between Tax and candidate interacting cellular proteins were confirmed by glutathione S-transferase (GST) pulldown assays, co-immunoprecipitation, and confocal microscopy. Functional interactions between Tax and one interacting protein, tristetraprolin (TTP), were assessed by analyzing the expression of tumor necrosis factor-alpha (TNF-alpha), which is regulated by TTP, in mammalian cells (HeLa, D17, HEK 293, and RAW 264.7) transiently transfected with combinations of intact and mutant Tax and TTP. RESULTS: We obtained seven interacting cellular proteins, of which one, TTP, was further characterized. Tax and TTP were found to interact specifically through their respective carboxyl-terminal domains. The proteins colocalized in the cytoplasm in a region surrounding the nucleus of HeLa cells. Furthermore, coexpression of Tax was associated with nuclear accumulation of TTP. TTP is an immediate-early protein that inhibits expression of TNF-alpha at the post-transcriptional level. Expression of Tax reverted this inhibition, both in transient transfection experiments and in stably transfected macrophage cell lines. CONCLUSION: Tax, through its interactions with the TTP repressor, indirectly increases TNF-alpha expression. This observation is of importance for the cell transformation process induced by leukemogenic retroviruses, because TNF-alpha overexpression plays a central role in pathogenesis. [less ▲]

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See detailAnalytic quantification of solar lentigines lightening by a 2% hydroquinone-cyclodextrin formulation.
Petit, Ludivine; Pierard, Gérald ULg

in Journal of the European Academy of Dermatology & Venereology (2003), 17(5), 546-9

BACKGROUND: The innate melanin pigmentation of skin is modulated during lifetime by a series of factors, including ageing and chronic ultraviolet light exposure. Actinic lentigines may be of particular ... [more ▼]

BACKGROUND: The innate melanin pigmentation of skin is modulated during lifetime by a series of factors, including ageing and chronic ultraviolet light exposure. Actinic lentigines may be of particular concern from a cosmetic point of view. Conventional hypopigmenting agents are usually deceptive. Using cyclodextrins to form inclusion compounds with these agents might represent a more active drug delivery system. OBJECTIVE: To assess sensitive and objective methods predicting the effects of a 2% hydroquinone-cyclodextrin formulation on solar lentigines. STUDY DESIGN: Thirty Asian adults applied a 2% hydroquinone-cyclodextrin formulation once daily on solar lentigines of a forearm for 2 months. The other untreated forearm served as a control. Monthly assessments were performed using skin colorimetry and fluorescence video recording combined with image analysis. Corneomelametry following photodensitometry of cyanoacrylate skin surface strippings was performed after melanin staining of the samples. RESULTS: The control untreated solar lentigines showed no significant variations in the biometrological parameters. By contrast, the test formulation induced lightening of the solar lentigines. Corneomelametry disclosed improvement after 1 months' treatment, whereas the other assessments only reached significance after 2 months. CONCLUSIONS: A 2% hydroquinone-cyclodextrin formulation proved to be effective in lightening actinic lentigines. Corneomelametry predicted the effects discernible at a later stage by in vivo colour assessments of the melanin content. [less ▲]

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See detailLoss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice
Robaye, B.; Ghanem, E.; Wilkin, F. et al

in Molecular Pharmacology (2003), 63(4), 777-783

The P2Y4 receptor is responsive to UTP in human and to ATP and UTP in rodents. With the aim of identifying its pharmacotherapeutic interest, we generated P2Y4-null mice by a classic gene targeting method ... [more ▼]

The P2Y4 receptor is responsive to UTP in human and to ATP and UTP in rodents. With the aim of identifying its pharmacotherapeutic interest, we generated P2Y4-null mice by a classic gene targeting method. The proportion of genotypes was consistent with X-linked Mendelian transmission. Gene inactivation was checked by the complete disappearance of P2Y4 receptor mRNA from liver, stomach, and intestine. The P2Y4-null mice had a grossly normal behavior, growth, and reproduction. Chloride secretion by the jejunal epithelium was assessed in Ussing chambers by the measurement of the short circuit current in the presence of phlorizin. We show here that the UTP- and ATPinduced chloride secretory responses observed in wild-type mice are abolished in P2Y4-null mice. This is the first clearcut demonstration of a biological role of the P2Y4 receptor [less ▲]

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See detailEffets du protocole GPG sur l’activité ovarienne
Hanzen, Christian ULg; Boudry, B.; Drion, Pierre ULg

in Point Vétérinaire (2003), 34(237), 26-30

The GPG protocol or OvSynch includes an injection of GnRH and followed seven days later by an injection of PgF(2alpha), which is preceded forty-eight hours earlier by a second injection of GnRH. The ... [more ▼]

The GPG protocol or OvSynch includes an injection of GnRH and followed seven days later by an injection of PgF(2alpha), which is preceded forty-eight hours earlier by a second injection of GnRH. The effects of GnRH on follicular tissue are either ovulation or luteinization depending at which stage of the cycle the cow is injected i.e. metoestrus, dioestrus or end of dioestrus. Observation of one or the other effect suggests a close association between the stage of follicular development, the function of the follicular tissue present and also the concentration of progesterone. [less ▲]

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See detailCalculation of bovine haemoglobin oxygen saturation by algorithms integrating age, haemoglobin content, blood pH, partial pressures of oxygen and carbon dioxide in the blood, and temperature.
Detry, Benoit; Cambier, Carole ULg; Frans, A. et al

in Veterinary Journal (2003), 165(3), 258-265

In human and veterinary medicine, arterial and venous haemoglobin oxygen saturations are often used to estimate the severity of a disease and to guide therapeutic decisions. In veterinary medicine ... [more ▼]

In human and veterinary medicine, arterial and venous haemoglobin oxygen saturations are often used to estimate the severity of a disease and to guide therapeutic decisions. In veterinary medicine, haemoglobin oxygen saturation (SO(2)) is usually calculated using a blood gas analyser and algorithms developed for humans. It is possible, therefore, that the values obtained in animals may be distorted, particularly in animals with a high haemoglobin oxygen affinity, like young calves. In order to verify this hypothesis, we compared the arterial (SaO(2)) and venous (SvO(2)) haemoglobin oxygen saturations calculated using three different algorithms, and the oxygen exchange fraction (OEF) at the tissue level, which is the degree of haemoglobin desaturation between arterial and venous blood (SaO(2)-SvO(2)), with the values obtained from the whole bovine oxygen equilibrium curve (OEC) determined by a reference method. The blood gas analysers underestimated SvO(2) values; consequently, the OEF was overestimated (by about 10%). Two methods of reducing these errors were assessed. As the haemoglobin oxygen affinity decreases during the first month of life in calves a relationship between PO(2) at 50% haemoglobin saturation (P50) and age was established in order to correct the calculated values of venous and arterial SO(2), taking into account the estimated position of the OEC. This method markedly reduced the error for SvO(2) and OEF. Secondly, the SO(2) was calculated using a mathematical model taking into account the age of the animal and the specific effects of pH, PCO(2), and temperature on the bovine OEC. Using this method, the mean difference between the OEF values calculated using the mathematical model and those calculated by the reference method was close to zero. The errors produced by blood gas analysers can thus be minimised in two ways: firstly, by simply introducing a P50 estimated from the age of the calf into the analyser before the measurement; and secondly, by calculating the SO(2) using a mathematical model applied to the bovine OEC. [less ▲]

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See detailStandardized test mixture for the characterization of comprehensive two-dimensional gas chromatography columns: the Phillips mix
Dimandja; Clouden; Colon et al

in Journal of Chromatography. A (2003), 1019

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See detailHorizontal And Vertical Co2 Advection In A Sloping Forest
Aubinet, Marc ULg; Heinesch, Bernard ULg; Yernaux, Michel ULg

in Boundary-Layer Meteorology (2003), 108(3),

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See detailMaking sense of the industrial revolution, English economy and society 1700-1850.
Geerkens, Eric ULg

in Revue Belge de Philologie et d'Histoire (2003), 81(2), 519-521

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See detailSolution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance.
Melckebeke, Helene Van; Vreuls, Christelle ULg; Gans, Pierre et al

in Journal of Molecular Biology (2003), 333(4), 711-20

beta-Lactamase and penicillin-binding protein PBP2' mediate staphylococcal resistance to beta-lactam antibiotics, which are otherwise highly clinically effective. Two repressors (BlaI and MecI) regulate ... [more ▼]

beta-Lactamase and penicillin-binding protein PBP2' mediate staphylococcal resistance to beta-lactam antibiotics, which are otherwise highly clinically effective. Two repressors (BlaI and MecI) regulate expression of these inducible proteins. Here, we present the first solution structure of the 82 amino acid residue DNA-binding domain of Bacillus licheniformis BlaI which is very similar in primary sequence to the medically significant Staphyloccocal BlaI and MecI proteins. This structure is composed of a compact core of three alpha-helices and a three-stranded beta-sheet typical of the winged helix protein (WHP) family. The protein/DNA complex was studied by NMR chemical shift comparison between the free and complexed forms of BlaI. Residues involved in DNA interaction were identified and a WHP canonical model of interaction with the operators is proposed. In this model, specific contacts occur between the base-pairs of the TACA motif and conserved amino acid residues of the repressor helix H3. These results help toward understanding the repression and induction mechanism of the genes coding for beta-lactamase and PBP2'. [less ▲]

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See detailCompte-rendu de l'ouvrage de I. Loudon (ed.) : Western Medicine. An Illustrated History
Nissen, Cécile ULg

in Archives Internationales d'Histoire des Sciences (2003)

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