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See detailIntensive culture of juvenile and adult Eurasian perch (P. fluviatilis): effect of major biotic and abiotic factors on growth
Mélard, Charles ULg; Kestemont, P.; Grignard, J. C.

in Journal of Applied Ichthyology (1996), 12

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See detailThe frequency of cutaneous vasculitis is not increased in patients with rheumatoid arthritis treated with methotrexate
Kaye, O.; Beckers, C. C.; Paquet, P. et al

in Journal of Rheumatology (1996), 23(2), 253-257

OBJECTIVE: To analyse the frequency, type, and immunohistological features of clinical cutaneous vasculitis developing in patients with rheumatoid arthritis (RA) treated or not with methotrexate as well ... [more ▼]

OBJECTIVE: To analyse the frequency, type, and immunohistological features of clinical cutaneous vasculitis developing in patients with rheumatoid arthritis (RA) treated or not with methotrexate as well as their demographic, clinical and biological characteristics. METHODS: Ninety-one patients with RA receiving 9.5 mg/wk of methotrexate (MTX) were compared for an average observation time of 18 months to 130 matched patients with RA treated with various drugs excluding MTX. RESULTS: Whether receiving MTX or not, 5.4% of patients with RA developed a clinical cutaneous vasculitis. There were significant differences between both groups for 2 variables only: a higher percentage of polyneuropathies and a higher level of immune complex-plasma levels in non-MTX patients. The immunohistological analysis did not differentiate both groups. CONCLUSION: The percentage of cutaneous vasculitis that developed under MTX therapy was not different from that occurring as a natural complication of longstanding severe RA. [less ▲]

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See detailHyperfine structure of infrared Al II lines
Palmeri, P.; Biémont, Emile ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (1996), 29

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See detailFoaming Properties Of Surfactin, A Lipopeptide Biosurfactant From Bacillus Subtilis
Razafindralambo, Hary ULg; Paquot, Michel ULg; Baniel, Alain et al

in Journal of the American Oil Chemists' Society (1996), 73(1), 149-151

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam ... [more ▼]

Foaming properties of surfactin were investigated and compared to those of sodium dodecyl sulfate (SDS) and bovine serum albumin (BSA). Foams were formed by a bubbling technique. Evolution of the foam volume and the liquid in the foam was monitored with optical and conductimetric methods to characterize foam formation and stability. Excellent foaming properties of surfactin were shown by its higher ability to form and stabilize the foam at a concentration as low as 0.05 mg/mL, in comparison with SDS and BSA. Surfactin produced a foam with intermediate maximum density and stabilized the liquid in foam, as well as BSA. [less ▲]

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See detailRevisiting the evaluation of the performance of fluid-filled catheters
GERARD, P; POCHET, T; LAMBERMONT, Bernard ULg et al

in Medical & Biological Engineering & Computing (1996), 34

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See detailAn efficient procedure for the production of fatty acid hydroperoxides from hydrolyzed flax seed oil and soybean lipoxygenase.
Fauconnier, Marie-Laure ULg; Marlier, M.

in biotechnology techniques (1996), 10(11), 839-844

Production of 13-linolenic acid hydroperoxides Tom hydrolyzed flax seed oil using lipoxygenase extracted Tom soybean seedshas been achieved with high transformation yields (60 g.l.-1h-1) with a high ... [more ▼]

Production of 13-linolenic acid hydroperoxides Tom hydrolyzed flax seed oil using lipoxygenase extracted Tom soybean seedshas been achieved with high transformation yields (60 g.l.-1h-1) with a high purity (94 % of i3-isomers) in a 10 liter reactor without addition of any solvent or surfactant. The reaction limiting factor is, probably, the accessibility of the substrate to the enzyme. [less ▲]

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See detailIBD mapping of recessive traits in livestock: application to map the bovine syndactyly locus to chromosome 15
Charlier, Carole ULg; Farnir, Frédéric ULg; Berzi, P. et al

in Genome Research (1996), 6

Twelve animals affected with syndactyly or mulefoot were sampled in the Dutch black-and-white cattle population. Analysis of the pedigree data reveal that all of these individuals traced back to a single ... [more ▼]

Twelve animals affected with syndactyly or mulefoot were sampled in the Dutch black-and-white cattle population. Analysis of the pedigree data reveal that all of these individuals traced back to a single acknowledged carrier founder individual. Between seven and nine generations separated the founder from its 12 affected descendents. The 12 affected offspring were genotyped for a battery of 213 microsatellites spanning the 29 bovine autosomes. The resulting genotypes were analyzed using a maximum likelihood approach searching for shared homozygous haplotypes among affected individuals. Three candidate regions for the syndactyly locus emerged from this initial screening. syndactyly was shown to map to one of these candidate regions on chromosome 15 by genotyping 29 additional individuals linking founder and affected offspring and performing a conventional linkage analysis with the LINKAGE programs. This study illustrates the potential of identity-by-descent mapping in livestock populations. [less ▲]

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See detailEffects of PEEP on venous return
LAMBERMONT, Bernard ULg; DETRY, Olivier ULg; Defraigne, Jean-Olivier ULg et al

in American Journal of Respiratory & Critical Care Medicine (1996), 2

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See detailMaladie de Hodgkin et facteurs de croissance
Fillet, Georges ULg

in Tempo Médical (1996), 166

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See detailLigniculture et maintien de la fertilité des sols dans l'Ouest-Cameroun
Njoukam, Raphaël; Bock, Laurent ULg; Hebert, Jacques ULg et al

in Bois et Forêts des Tropiques (1996), (249), 33-49

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See detailRecently advanced computerized technology was applied to the investigation of morphometric, immunohistological and three-dimensional changes of the endometrial mucosa in order to evaluate quantitatively the effects of three doses of a new slow-release vaginal progesterone on the endometrium in post-menopausal women. A total of 20 menopausal women, deprived of ovarian function, were given oestrogen for 12 days and a combined therapy of oestrogen (administered orally) and progesterone for another 12 day period. Progesterone was administered vaginally through a new gel (Crinone) utilizing a bioadhesive, biocompatible polymer as a base to achieve a sustained release effect. An endometrial biopsy was taken before treatment, after oestrogen-only treatment and after the oestro-progestogen therapy. Before treatment, all the patients exhibited an atrophic endometrium. After oestrogen-only treatment, typical proliferative changes occurred: an increase in the endometrium thickness, an increase in the mitotic index, numerous cylinder-like glands and no coiled glands, and high concentrations of oestrogen receptors (ER) and progesterone receptors (PR). After the oestro-progestogen therapy, whatever the dose of progesterone given, a secretory transformation of the endometrial mucosa occurred, mitotic activity decreased significantly, more ramified and coiled glands were observed, and a decrease in PR content was noted in epithelial and stromal nuclei, and a decrease in PR content was also observed in epithelial nuclei but not in stromal nuclei. Accurate new techniques of image analysis have shown that crinone therapy could eliminate the proliferative effects of oestrogen treatment in post-menopausal women, despite doses as low as 45 mg of progesterone administered vaginally every other day. The results suggest that the sustained release effects of Crinone are clinically relevant.
Donnez, Jacques; NISOLLE, Michelle ULg; Casanas-Roux, Françoise et al

in Human Reproduction (1996), 11(1), 224-8

A computerized morphometrical investigation was performed on endometriotic tissue from the peritoneum (n = 225) and rectovaginal nodules (n = 65) to compare histologically and stereologically the ... [more ▼]

A computerized morphometrical investigation was performed on endometriotic tissue from the peritoneum (n = 225) and rectovaginal nodules (n = 65) to compare histologically and stereologically the rectovaginal septum endometriotic nodule to peritoneal endometriosis. Mitotic activity, stromal vascularization and the epithelium/stroma ratio were found to be significantly different in peritoneal and rectovaginal endometriosis. The evaluation revealed a major role of glandular epithelium in rectovaginal nodules where the stroma sometimes appeared absent around glandular epithelium. The study demonstrated opposite effects of gonadotrophin-releasing hormone agonists (GnRHa) and lynestrenol on the two lesions. Indeed, in peritoneal endometriosis, after GnRHa therapy, our study demonstrated a lower rate of mitosis and poor stromal vascularization. The same drug was unable to induce the same effects in the nodule although, in contrast, lynestrenol has a strong effect on nodule vascularization. In conclusion, it is suggested that the rectovaginal adenomyotic nodule is a specific disease, different from peritoneal endometriosis. It is not the consequence of 'deep infiltrating' endometriosis but can probably develop from Mullerian rests present in the rectovaginal septum. [less ▲]

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See detailPremière approche de la flore macrolichénique corticole de la Région de Bruxelles-Capitale en situation de dépollution au SO2
Tanghe, Martin; Richel, Thierry; Crisan, Florin et al

in Belgian Journal of Botany (1996), 129

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See detailImprovement in the inflammatory aspect of androgenetic alopecia. A pilot study with an antimicrobial lotion
Pierard, Gérald ULg; Pierard-Franchimont, Claudine ULg; Tassoudji, Nazli ULg et al

in Journal of Dermatological Treatment (1996), 7

Androgenetic alopecia (AGA) is a common yet poorly understood condition. In particular, the significance of inflammatory cells close to the infrainfundibulum of transitional hairs remains obscure. This ... [more ▼]

Androgenetic alopecia (AGA) is a common yet poorly understood condition. In particular, the significance of inflammatory cells close to the infrainfundibulum of transitional hairs remains obscure. This study was conducted in 20 men who used a lotion containing the antimicrobials, piroctone olamine and triclosan, regularly for 18 months. At entry, mild pruritus and abnormal hair loss were reported by the volunteers. During treatments, pruritus resolved rapidly. Comparison of clinical photographs and trichograms taken at 3-month intervals suggested signs of hair regrowth with moderate increase in density of transitional hairs. Biopsies taken at 6-month intervals were processed for immunohistochemistry. There was a decrease in the density of activated T cells in the region of the follicular infrainfundibulum and isthmus over time. UgG deposits found within the epithelial sheaths at entry to the study were absent in the subsequent biopsies. The volume of the sebaceous glands, as assessed by computerized morphometry, was not modified by the treatment. It was concluded that inflammation associated with AGA transitional hairs may be driven by the presence of microorganisms harboured in the infrainfundibulum. They may modulate the severity of AGA and may potentially be controllable. This offers a new possibility of prevention and partial reversal of hair loss in AGA. [less ▲]

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See detailExpansive benign lesions: treatment by laser.
Smets, Mireille; NISOLLE, Michelle ULg; Bassil, Salim et al

in European Journal of Obstetrics and Gynecology (1996), 65(1), 101-5

Submucous fibroids, polyps and dysfunctional bleeding are responsible for meno-metrorrhagia in women over 40 years of age. The authors describe the technique of hysteroscopic myomectomy and endometrial ... [more ▼]

Submucous fibroids, polyps and dysfunctional bleeding are responsible for meno-metrorrhagia in women over 40 years of age. The authors describe the technique of hysteroscopic myomectomy and endometrial ablation using the Nd-YAG laser and the advantages of the preoperative use of GnRH agonist therapy. They report their results in a series of 746 patients treated for meno-metrorrhagia (366 cases of myomectomy and 380 cases of endometrial ablation). [less ▲]

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See detailTests au sol du télescope spatial XMM
Mazy, Emmanuel ULg; Stockman, Yvan ULg; Rochus, Pierre ULg

in SupOptique Avenir 1996 page 14-16. (1996)

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See detailLe cas clinique du mois : syndrome de Moskowitz chez un patient traité par ticlopidine
FRANCHIMONT, D; Freres, Pierre ULg; LEBRUN, F et al

in Revue Médicale de Liège (1996), 51(3), 214-216

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See detailHacia una cartografía del boom. Una polémica en Zona Franca (ag.-dic.1972).
Vanden Berghe, Kristine ULg

in América. Cahiers du CRICCAL (1996), 15/16

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See detailCompte rendu de l'ouvrage de ANDORLINI Isabella (Edizione e commento a cura di), Trattato di medicina su papiro, Firenze, Istituto Papirologico "G. Vitelli", 1995
Marganne, Marie-Hélène ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1996), 71

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See detailAn investigation of the effects of daily physical education in kindergarten and elementary schools
Piéron, Maurice ULg; Cloes, Marc ULg; Delfosse, Catherine et al

in European Physical Education Review (1996), 2(2), 116-132

The project used different methods of data collection: tests, questionnaires and systematic observation of pupils and teachers. In developing a multiple viewpoint approach, we attenpted to sketch a ... [more ▼]

The project used different methods of data collection: tests, questionnaires and systematic observation of pupils and teachers. In developing a multiple viewpoint approach, we attenpted to sketch a detached view of the implementation of DPE and of tis results. Goals were as follows: (1) Exploring the possible effects of the programme in various areas of children's life that do not arise directly from their activities during physical education lessons. (2) Identifying children's school-life context, in order to identify factors influencing several effects of DPE. The various viewports considered, the results, and the knowledge of external variables all allowed us to identify a convergent package of indications, thus allowing us to think in terms of causality. Often, the benefits came from the children's involvement in the experimental programme. Improvements of motor performance in primary school age children arise from a maturation process and from practice and learning. Nevertheless, it is particularly hard to identify the relative contributions of these two sources. Tracing pupil's development, fro the starting level at beginning of the school year, appeared to allow isolation of the part played by children's activities whitin the school environement. In all grade levels, comparisons confirmed pilot classes superiority. Performances were significantly better in many tests. However, during the year, it seemed that the development of performance due to maturation masked the potential effects of physical activities. A decline in favourable attitudes was observed in every school at the beginning and the end of the school year. A slide from very favourable attitudes towards simply favourable attitudes was observed. ... [less ▲]

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See detailEffects of castration on fear reactions of male sheep.
Vandenheede, Marc ULg; Bouissou, Marie-France

in Applied Animal Behaviour Science (1996), 47

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See detailOn the helminthofauna of wild mammals (Rodentia, Insectivora ans Lagomorpha) in Azores archipelago (Portugal)
Casanova, J. C.; Miquel, Jordi; Fons, Roger et al

in Vie et milieu (1996), 46(3-4), 253-259

The faunistic and ecological study of the helminthfaunas of mammals in Azorean islands is considered. 103 rodents (Rattus rattus L., 1758 and Mus musculus L., 1758) 9 insectivores (Erinaceus europaeus L ... [more ▼]

The faunistic and ecological study of the helminthfaunas of mammals in Azorean islands is considered. 103 rodents (Rattus rattus L., 1758 and Mus musculus L., 1758) 9 insectivores (Erinaceus europaeus L., 1758) and 19 lagomorphs (Oryctolagus cuniculus L., 1758) were analysed. The hosts been captured in several biotopes of thre islands (São Miguel, Terceira and Flores). 27 helminth species were detected (3 Digenea Trematoda, 5 Cestoda, 18 Nematoda and 1 Acantocephala). All hosts species show high prevalences and no significant differences were found between different islands. The helminthfaunas show typical features of a young island parasitofaunas. [less ▲]

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See detailRole of the metallothioneins in metal regulation by the guillemot Uria aalge
Bouquegneau, Jean-Marie ULg; Debacker, Virginie ULg; Gobert, Sylvie ULg et al

in Comparative Biochemistry and Physiology. C : Comparative Pharmacology and Toxicology (1996), 113C(2), 135-139

Guillemots, like other seabird species living in the North Sea, appear to be heavily contaminated by copper. Metallothioneins are present in both liver and kidney but, at least in the specimens stranded ... [more ▼]

Guillemots, like other seabird species living in the North Sea, appear to be heavily contaminated by copper. Metallothioneins are present in both liver and kidney but, at least in the specimens stranded along the Belgian coast, fail to maintain constant the copper, zinc and cadmium load of the high molecular weight soluble proteins of both organs, stressing the potential toxic role of these metals, mainly copper. [less ▲]

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See detailDeffand, Marie de Vichy-Chamrond, marquise du
Tilkin, Françoise ULg

in Voir barré (1996), 12-13

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See detailModulation Of Cd3-Gamma Gene Expression After Hiv Type 1 Infection Of The We17/10 T Cell Line Is Progressive And Occurs In Concert With Decreased Production Of Viral P24 Antigen
Willardgallo, Ke.; Delmellewibaut, C.; Segurazapata, I. et al

in Aids Research and Human Retroviruses (1996), 12(8),

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See detail"Aquí, allá y en todas partes": La (con)version de la Identidad Caribeña por Michelle Cliff
Ledent, Bénédicte ULg; Ortega, María Teresa

in Anales del Caribe (1996), 16-18

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See detailEvaluation du débit sanguin au niveau du quadriceps électrostimulé et contracté volontairement
Vanderthommen, Marc ULg; BAUVIR, Philippe ULg; Depresseux, J.C. et al

in Annales de Kinésithérapie (1996), 23(1), 20-23

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See detailIntestinal Permeability in Crohn's Disease
Franchimont, D.; Louis, Edouard ULg; Simon, Sarah ULg et al

in Acta Gastro-Enterologica Belgica (1996), 59(1, Jan-Mar), 15-9

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the ... [more ▼]

We summarize the anatomical and physiological basis and the ways of measuring the intestinal permeability. We review the studies of the intestinal permeability in Crohn's disease. We analyse the involvement of an abnormal intestinal permeability in the pathogenesis of Crohn's disease, as a primary or secondary defect. We discuss the potential usefulness of the measure of intestinal permeability in Crohn's disease activity assessment, relapse prediction and efficacy of treatment. [less ▲]

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See detailGranuloma tuberculoide post-herpético en un paciente con leucemia linfocítica crónica
Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg; Pierard, Gérald ULg

in Medicina Cutanea Ibero-Latino-Americana (1996), 24

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See detailStorm surges in the Arabian/Persian Gulf
Djenidi, Salim ULg; Neuberg, Luc

in Bulletin de la Société Royale des Sciences de Liège (1996), 65

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See detailHyperfine structure of Sc I by Infrared Fourier Transform Spectroscopy
Aboussaïd, A.; Carleer, M.; Hurtmans, D. et al

in Physica Scripta (1996), 53

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See detailSimulation of pumping and artificial recharge in the phreatic aquifer near Bucarest (Romania)
Stefanescu, Christian; Dassargues, Alain ULg

in Hydrogeology Journal (1996), 4(3), 72-83

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See detailLa genèse du héros médiocre. Simenon à l'époque Fayard
Denis, Benoît ULg

in Traces. Travaux du Centre d'Études Georges Simenon (1996), (8), 27-42

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See detailA Non-Cofactor Role of Thiamine Derivatives in Excitable Cells?
Bettendorff, Lucien ULg

in Archives of Physiology & Biochemistry (1996), 104(6), 745-751

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain ... [more ▼]

Thiamine diphosphate (TDP) is an important cofactor of pyruvate (PDH) and alpha-ketoglutarate (KGDH) dehydrogenases and transketolase. Thiamine deficiency leads to reversible and irreversible brain lesions due to impaired oxidative metabolism. A specific non-cofactor role for thiamine has also been proposed in excitable cells and thiamine triphosphate (TTP) might be involved in the regulation of ion channels. Thiamine is taken up by neuroblastoma cells through a high affinity transporter. Inside the cells, it is rapidly phosphorylated to TDP. This high turnover TDP pool is the precursor for TTP. Most of the TDP however has a low turnover and is associated with PDH and KGDH in mitochondria. In excised inside-out patches from neuroblastoma cells, TTP, at a concentration of 1 microM, activates chloride channels of large unitary conductance, the so-called maxi-Cl- channels. These channels are inhibited by oxythiamine from the outide. In addition to the role of TTP in the regulation of chloride channels, thiamine itself, or a presently unknown analog, may have trophic effects on neuronal cells. [less ▲]

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See detailAntithrombin III in the therapy of severe sepsis
Lamy, Maurice ULg; Eisele, B.

in Biomedical Progress (1996), 9

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See detailModelling the competition between two phytoplanktonic species
Elkafazi, Abderahman; Djenidi, Salim ULg; Nihoul, Jacques ULg

in Bulletin de la Société Royale des Sciences de Liège (1996), 65

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See detailCompte rendu de Villages et villageois au Moyen Age, Paris, 1992
George, Philippe ULg

in Cahiers de Clio (1996)

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See detailYounger age as a bad prognostic factor in patients with carcinoma of the cervix.
Delaloye, J-F; Pampallona, S; COUCKE, Philippe ULg et al

in European Journal of Obstetrics & Gynecology & Reproductive Biology (1996)

Objective: To verify the influence of age on the prognosis of cervix carcinoma. Study design: Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre ... [more ▼]

Objective: To verify the influence of age on the prognosis of cervix carcinoma. Study design: Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: _<45, 46-60, 61-69 and > 70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis. Results: The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages. Conclusion: Age under 45 years is a bad prognostic factor in carcinoma of the cervix. [less ▲]

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See detailEffets du massage par appareil semi automatique : Etude scintigraphique et tonométrique
Crielaard, Jean-Michel ULg; Vanderthommen, Marc ULg; Dauchat, L. et al

in Kinésitherapie, les Annales (1996), 23(3), 102-105

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See detailModélisation en hydrogéologie - De modelisatie in de hydrogeologie
Dassargues, Alain ULg; Vander Velpen, B.; Vercruysse, J.

in BLUG Tijdschrift - Revue de l'UBLG (1996)

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See detailThe Appearance of CH3+ Ions from Methyl Halides by resonant photoionization. A translational energy surprisal analysis. Part I. CH3F.
Momigny, J.; Locht, Robert ULg

in Chemical Physics (1996), 206

A surprisal analysis has been applied to the translational energy distribution (TED) of CH3++F from CH3F giving rise to a new and deeper insight into the dissociation dynamics involved in the process. For ... [more ▼]

A surprisal analysis has been applied to the translational energy distribution (TED) of CH3++F from CH3F giving rise to a new and deeper insight into the dissociation dynamics involved in the process. For both the 16.5 eV and 21.22 eV photon energies used, the direct population at different energy levels of the B2E state of CH3F+ which is radiationlessly coupled to the repulsive CH3F+(A2A1) state, gives rise to wide and negatively surprised total TEDs. At both energies they have to be ascribed to severe limitations in the vibrational excitation of CH3+. Additionally, in the case of 21.22 eV photons, a non-statistical expression has to be used to account for the density of translational states. At both photon energies, the population of the CH3F+ electronic states through autoionization of Rydberg states accounts for (i) the concurrent appearance of TEDs governed by a pure RRKM behavour and (ii) the positively surprised TEDs where the angular momentum conservation plays an important role. At 16.85 eV photon energy the distributions are assigned to CH3F+ (X2E)->CH3+ (X1A'1)+F. At 21.22 eV photon energy, doubly excited electronic states of CH3F+ are assumed to take part and they are correlated with CH3+ (3A")+F channel. [less ▲]

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See detailDe la phrase au texte dans l'enseignement d'une langue étrangère
Defays, Jean-Marc ULg

in Dialogues et cultures (1996), 40

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See detailPhylogenetic Relationships of Nonaxenic Filamentous Cyanobacterial Strains Based on 16S rRNA Sequence Analysis
Nelissen, Bart; De Baere, Raymond; Wilmotte, Annick ULg et al

in Journal of Molecular Evolution (1996), 42

In order to determine the nearly complete 16S rRNA gene sequences of cyanobacteria originating from nonaxenic cultures, a cyanobacterium-specific oligonucleotide probe was developed to distinguish ... [more ▼]

In order to determine the nearly complete 16S rRNA gene sequences of cyanobacteria originating from nonaxenic cultures, a cyanobacterium-specific oligonucleotide probe was developed to distinguish polymerase chain reaction (PCR) products of the cyanobacterial rRNA operons from those resulting from amplification of contaminating bacteria. Using this screening method the 16S rRNA genes of four nonaxenic filamentous cyanobacterial strains belonging to the genera Leptolyngbya and OscitIatoria were cloned and sequenced. For the genus Leptolyngbya, the 16S rRNA sequence of the axenic strain PCC 73110 was also determined. Phylogenetic trees were constructed based on complete and partial sequences. The results show that the strains Leptolyngbya Jbveolarum Kom~rek 1964/112, Leptolyngbya sp. VRUC 135 Albertano t985/1, and LeptoIyngbya boryanum PCC 73110 belong to the same cluster. Strain Oscillatoria cf. corallinae SAG 8.92, which contains the rare photosynthetic pigment CUphycoerythrin, is not closely related to other CUphycoerythrin- containing cyanobacteria. Oscillatoria agardhii CYA 18, which is a representative of planktonic Oscillatoria species that form toxic blooms in Norwegian inland waters, has no close relatives in the tree. [less ▲]

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See detailMembrane-type matrix metalloproteinase-1 expression at the site of human placentation
Nawrocki, B.; Polette, M. E.; Marchand, V. et al

in Placenta (1996), 17(8), 565-72

Human trophoblast implantation is a highly regulated process of invasion that requires action of proteolytic enzymes to degrade extracellular matrix components of the endometrium. Among these enzymes ... [more ▼]

Human trophoblast implantation is a highly regulated process of invasion that requires action of proteolytic enzymes to degrade extracellular matrix components of the endometrium. Among these enzymes, matrix metalloproteinases (MMPs) seem to be particularly important in this degradative process. We previously showed that gelatinase A is extensively expressed in vivo in the human placenta. A new MMP, MT-MMP-1 (membrane-type matrix metalloproteinase-1), which is thought to activate progelatinase A, has recently been described. In this study, we examined the expression of MT-MMP-1, by immunohistochemistry and in situ hybridization, in human placental bed biopsies taken during the first trimester of gestation. Human first trimester intermediate trophoblasts synthesized MT-MMP-1 mRNAs and the protein. The MT-MMP-1 pattern of distribution in placental beds was similar to that of gelatinase A, suggesting a pivotal role for MT-MMP-1 in placentation, perhaps by activating progelatinase A. [less ▲]

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See detailRetizonomonoletes hunanensis Fang et al. 1993 and the Retispora lepidophyta morphon.
Steemans, Philippe ULg; Fang, Xiaosi; Streel, Maurice ULg

in Inst. Géol. de l'Univ. Louvain (1996), 36

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See detailDescription lithostratigraphique et pétrographie du sondage 221E87 de Villers-devant-Orval (Trias, Lias de la Gaume, Belgique)
Boulvain, Frédéric ULg; Delsate, D.; Gulinck, M. et al

in Professional Paper Belgian Geological Survey (1996), 281

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See detailcr de E. Wente, Letters from Ancient Egypt
Winand, Jean ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1996), 71(141), 57-62

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See detailImprint and Brush Cytology in the Diagnosis of Canine Intranasal Tumours
Clercx, Cécile ULg; Wallon, J.; Gilbert, S. et al

in Journal of Small Animal Practice (1996), 37(9), 423-7

Fifty-four dogs with nasal tumours were included in this study. Based on histopathology 52 tumours were malignant (36 epithelial and 16 mesenchymal) and two were benign (one oncocytoma and one ... [more ▼]

Fifty-four dogs with nasal tumours were included in this study. Based on histopathology 52 tumours were malignant (36 epithelial and 16 mesenchymal) and two were benign (one oncocytoma and one pleiomorphic adenoma). Malignancy was significantly more frequently diagnosed by imprint cytology (81 per cent of the cases) than by brush cytology (56 per cent). Brush cytology was a significantly more sensitive technique in epithelial than in mesenchymal tumours, while the sensitivity of imprint cytology was not affected by the histological type. Brush cytology determined an epithelial origin in 88 per cent of epithelial tumours, and imprint cytology in 90 per cent. In mesenchymal tumours, the scores were significantly lower, the histological type being determined in only 20 per cent and 50 per cent, using brush and imprint cytology, respectively. [less ▲]

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See detailLes drogues prohibées
Lequarré, Françoise; Verjans, Pierre ULg

in Courrier Hebdomadaire du CRISP (1996), (n° 1506-1507),

Les politiques publiques vis-à-vis des produits psychotropes illustrent le va-et-vient entre une politique sécuritaire et une politique sanitaire, en fonction des produits et en fonction des époques.

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See detailActivités sportives et système immunitaire
PIRNAY, Freddy ULg; Bury, Thierry ULg

in Médecine et Hygiène (1996), 54

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See detailRecommendations for registration of drugs used in the treatment of osteoarthritis
Dougados, M; Devogelaer, JP; Annefeldt, M et al

in Annals of the Rheumatic Diseases (1996), 55

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See detailCalcitonin
Reginster, Jean-Yves ULg

in Current Opinion in Orthopaedics (1996), 7

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See detailTabac et maladie parodontale
Geerts, Sabine ULg

in Actualités Dentaires de l'Université de Liège (1996), 19

Le tabac est un facteur aggravant la parodontite. Beaucoup d'études cliniques ont été menées et ont souvent montré des résultats contradictoires. Cet article est une revue de littérature sur la relation ... [more ▼]

Le tabac est un facteur aggravant la parodontite. Beaucoup d'études cliniques ont été menées et ont souvent montré des résultats contradictoires. Cet article est une revue de littérature sur la relation entre le tabagisme et la parodontite. [less ▲]

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See detailL’ostéoporose en questions : plus dure sera la chute
Reginster, Jean-Yves ULg

in Stethoscopie Magazine (1996), 63

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See detailSuccessful Tricuspid Valve Replacement and Pulmonary Valvulotomy for Carcinoid Heart Disease
DEFRAIGNE, Jean ULg; Jerusalem, O.; Soyeur, Daniel ULg et al

in Acta Chirurgica Belgica (1996), 96(4), 170-6

A case of successful tricuspid valve replacement with a mechanical prosthesis and pulmonary valvulotomy for carcinoid heart disease is reported. The patient was a 61 years old women. The primary tumor was ... [more ▼]

A case of successful tricuspid valve replacement with a mechanical prosthesis and pulmonary valvulotomy for carcinoid heart disease is reported. The patient was a 61 years old women. The primary tumor was in the terminal ileum. Liver metastasis and carcinoid syndrome were present since 8 years. After cardiac surgery, the patient survived 38 months and late death was related to disseminated metastasis. Even in case of metastasis, carcinoid tumor is slow growing. Without cardiac operation for correction of valvular lesions, terminal symptoms and death may often be related to cardiac operation for correction of valvular lesions, terminal symptoms and death may often be related to cardiac failure rather than to tumoral growth. Thus, even in presence of metastasis, cardiac surgery may be mandatory to improve both quality of life and survival. [less ▲]

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See detailPurification of soybean lipoxygenase isoenzyme-1 and characterization of its inhibition by 13-hydroperoxides.
Fauconnier, Marie-Laure ULg; Marlier, M.

in Grasas y Aceites (1996), 47(4), 242-246

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See detailTransition probabilities for forbidden lines of Fe III
Quinet, Pascal ULg

in Astronomy and Astrophysics. Supplement Series (1996), 116

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See detailAge and correlation of the Barreinrinha Formation (Curua Group, Amazon Basin) : new evidence from the Miospore biostratigraphy
Loboziak, S.; Melo, J.H.G.; Rodriguez, R. et al

in Anais da Academia Brasileira de Ciencias (1996), 68(2), 207-212

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See detailOne-pot enzymatic synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc sequence with in situ UDP-Gal regeneration.
Hokke, Cornelis H; Zervosen, Astrid ULg; Elling, Lothar et al

in Glycoconjugate Journal (1996), 13(4), 687-92

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely ... [more ▼]

The trisaccharide Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was enzymatically synthesized, with in situ UDP-Gal regeneration. By combination in one pot of only four enzymes, namely, sucrose synthase, UDP-Glc 4'-epimerase, UDP-Gal:GlcNAc beta 4-galactosyltransferase and UDP-Gal:Gal beta 1-->4GlcNAc alpha 3-galactosyltransferase, Gal alpha 1-->3Gal beta 1-->4GlcNAc beta 1-->O-(CH2)8COOCH3 was formed in a 2.2 mumol ml-1 yield starting from the acceptor GlcNAc beta 1-->O-(CH2)8COOCH3. This is an efficient and convenient method for the synthesis of the Gal alpha 1-->3Gal beta 1-->4GlcNAc epitope which pays an important role in various biological and immunological processes. [less ▲]

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See detailExperimental research on the determination of the main parameters affecting the behaviour of reinforced concrete columns under fire conditions
Dotreppe, Jean-Claude ULg; Franssen, Jean-Marc ULg; Bruls, Alois et al

in Magazine of Concrete Research (1996), 48(6), 117-127

The design of reinforced concrete columns under fire conditions is generally made on the basis of national and international recommendations. The CEB/FIP recommendations have been used for many years ... [more ▼]

The design of reinforced concrete columns under fire conditions is generally made on the basis of national and international recommendations. The CEB/FIP recommendations have been used for many years. Recently, in the framework of the Eurocodes, the document ENV 1992-1-2 (Eurocode 2-1-2), Structural fire design, has been approved by Commission CEN/TC250/SC2 of the European Committee for Standardization. In the CEB/FIP documents and in Eurocode 2-1-2 the main part is devoted to design from tabulated data containing the dimensions of the cross-sections and values for the concrete cover. The use of simplified calculation methods is not current practice for concrete elements, while they are widely used in the case of steel. The determination of the temperature distribution in the cross-section does not facilitate the development of a simplified method. Furthermore, in columns there is a wide scatter of experimental results. In order to gain additional information, an extensive experimental research programme on the behaviour of reinforced concrete columns under fire conditions, financially supported by the Belgian Funds for Fundamental Collective Research (FRFC-FKFO), has been performed at the Universities of Liege and Ghent. In this article the results of this research are presented and the influence of the main parameters is analysed. [less ▲]

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See detailA simple technique to relieve Tribolium castaneum (Coleoptera: Tenebrionidae) of Acarophenax tribolii (Acarina: Pyemotidae).
Arnaud, Ludovic; Mignon, Jacques ULg; Gilson, Jean-Claude et al

in Tribolium Information Bulletin (1996), 36

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See detailUne statuette d'adorant de l'âge du Bronze ancien provenant de Tell Amarna (Syrie)
Tunca, Önhan ULg

in Colloctanea Orientalia. Histoire, arts de l'espace et industrie de la terre. Etudes offertes en hommage à Agnès Spycket (1996)

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See detailNew Devonian fossil localities in Bolivia
Blieck, A; Gagnier, PY; Bigey, FP et al

in Journal of South American Earth Sciences (1996), 9(5-6), 295--308

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See detailFréquence et importance du charriage dans des rivières à charge de fond graveleuse
Petit, François ULg; Pauquet, A.; Pissart, Albert ULg

in Géomorphologie : Relief, Processus, Environnement (1996)

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See detailOscillator strengths for Ca-like iron, cobalt and nickel (Fe VII, Co VIII, Ni IX)
Quinet, Pascal ULg; Hansen, J E

in Journal of Physics : B Atomic Molecular & Optical Physics (1996), 29

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See detailProduction of anti-PMSG antibodies and its relation to the productivity of rabbit does
Lebas, F.; Theau-Clement, M.; Remy, Benoît ULg et al

in World Rabbit Science (1996), 4(2), 57-62

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See detailAu sud, rien de nouveau…
Verjans, Pierre ULg

in Res Publica (1996), Volume XXXVIII(n°3/4), 547-554

Le passage des élections nationales à des élections fédérales d'un côté et régionales de l'autre n'a pas modifié les rapports de force régionaux ni nationaux. A court terme tout au moins.

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See detailThe BFKL pomeron: Can it be detected?
Cudell, Jean-René ULg; Donnachie, A.; Landshoff, P. V.

in Nuclear Physics B (1996), 482

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See detailComparative evaluation of impulse oscillometry and a monofrequency forced oscillation technique in clinically healthy calves undergoing bronchochallenges
Reinhold, Petra; MacLeod, D.; Lekeux, Pierre ULg

in Research in Veterinary Science (1996), 61

Multifrequency impulse oscillometry (IOS) was compared with a monofrequency forced oscillation technique (MFO) in calves undergoing experimentally induced bronchoconstriction and subsequent ... [more ▼]

Multifrequency impulse oscillometry (IOS) was compared with a monofrequency forced oscillation technique (MFO) in calves undergoing experimentally induced bronchoconstriction and subsequent bronchodilatation. The dynamic lung compliance (Cdyn) was also measured by conventional methods. For each test, the baseline mean and the responses to saline, a bronchoconstrictive agent (carbachol) and a bronchodilator (fenoterolhydrobromide) were calculated. Using the IOS, the information was markedly frequency-dependent. The resistance (R) and the magnitude of respiratory impedance (Z) were only sensitive at 5 Hz, leading to negative frequency dependence of these parameters as an indicator of peripheral airway obstruction. A high sensitivity for reactance (X) and phase angle phi values was observed between 5 and 20 Hz. For MFO (10 Hz), the parameters Ros (which includes resistive and capacitive components of the respiratory system), phase shift (psi), and the oscillatory derived compliance of the respiratory system (Crs) were of the greatest clinical potential. Crs showed a significant coefficient of linear correlation (r = 0.88, P < 0.001) with Cdyn. At the 10 Hz test frequency similar results were observed with MFO and IOS, suggesting that for healthy calves the measurement effect of an impulse is not significant. With respect to peripheral airway calibre, a test frequency less than 10 Hz appeared to be most sensitive and least variable. [less ▲]

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See detailRecommendations for the registration of agents used in the prevention and treatment of glucocorticoid-induced osteoporosis
Compston, JE; Audran, M; Avouac, B et al

in Calcified Tissue International (1996), 59

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See detailManger juste. Les droits de l'animal dans les encyclopédies de 1750 à 1800. De l'éthique au politique
Strivay, Lucienne ULg

in Colloques d'Histoire des Connaissances Zoologiques (1996), 7

Les encyclopédistes du 18° inclurent leurs définitions de la spécificité humaine par rapport à celle de l'animal dans leur nouvelle synthèse du savoir. A la même époque, resurgit le concept des "droits de ... [more ▼]

Les encyclopédistes du 18° inclurent leurs définitions de la spécificité humaine par rapport à celle de l'animal dans leur nouvelle synthèse du savoir. A la même époque, resurgit le concept des "droits de l'animal" (relayant les anciens procès intentés à des animaux). La communication examine comment Diderot et d'Alembert, Panckoucke, Robinet, De Lisle de Sales, Valmont de Bomare, etc., s'y prirent pour concilier les droits de l'homme et ceux de l'animal dans les articles de leurs encyclopédies. Si l'animal appartient à la catégorie de "l'autre", sa proximité avec l'homme, en raison du développement des premières intuitions transformistes et du sensualisme matérialiste, s'affirme de plus en plus, en opposition au cartésianisme qui considérait l'animal comme une machine et l'écartait, par essence, de l'homme et de Dieu. En conséquence, les points de vue qui s'expriment au siècle des Lumières au sujet des animaux ont suscité des idées dérangeantes sur le lien unissant tous les êtres vivants entre eux et, d'autre part, ils ont soulevé de nouvelles questions, les unes théoriques : au sujet de l'origine des espèces, les autres pratiques : sur le droit de l'homme à manger les animaux, le choix des viandes et ses conséquences morales, voire politiques. Car, fondé comme il l'est sur des formes de violence publique ou privée, l'abattage des animaux afin de produire de la viande a toujours eu de nombreuses implications, notamment sociales, propres à induire finalement des réformes ou des changements d'ensemble. [less ▲]

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See detailMaladie pulmonaire obstructive chronique dans l'espèce équine
Vandenput, Sandrina ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1996), 140

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This ... [more ▼]

Equine chronic obstructive pulmonary disease (COPD), also known as <<heaves>>, is a respiratory syndrome associated with stabling or exposure to hay or conditions in which molds or dust prevail. This paper reviews the different aspects of the equine COPD. Etiology, potential evolutions, treatment and prevention of this disease are evolved. [less ▲]

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See detailSelection and identification of lumped models of the arterial vasculature using multiple regression and backward elimination in the time domain
POCHET, T; GERARD, P; LAMBERMONT, Bernard ULg et al

in Medical & Biological Engineering & Computing (1996), 34

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See detailEnergy levels and oscillator strengths for transitions in Pd II
Quinet, Pascal ULg

in Physica Scripta (1996), 54

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See detailL'endotoxémie dans l'espèce équine. 1ère partie: étiologie et physiopathologie.
Amory, Hélène ULg

in Pratique Vétérinaire Equine (1996), 28

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See detailPhénomènes karstiques en milieux non carbonatés. Etudes de cavités et problématique de leur développement au Niger Occidental
Willems, Luc ULg; Pouclet, André; Lenoir, François et al

in Zeitschrift für Geomorphologie (1996)

The study of several caves in siliceous formations belonging to the Precambrian basement and its Cenozoic sedimentary cover brings to the fore the importante of an underground drainage network in relation ... [more ▼]

The study of several caves in siliceous formations belonging to the Precambrian basement and its Cenozoic sedimentary cover brings to the fore the importante of an underground drainage network in relation with crustal fracturation. This network guides the waler transfer from the land surface to the depth and generates géomorphologic phenomena similar to those in calcareous areas. The study of caves in a siliceous environmemts shows the importance of solution phenomena in their formation and also in that of West Niger landscapes. Therfore, a general model of topographic evolution îs proposed. [less ▲]

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See detailBactericidal activity against Pseudomonas aeruginosa is acquired by cultured human monocyte-derived macrophages after uptake of myeloperoxidase.
Mathy-Hartert, M.; Deby, Ginette ULg; Melin, Pierrette ULg et al

in Experientia (1996), 52(2), 167-74

Myeloperoxidase (MPO) is an enzyme located within polymorphonuclear neutrophils capable of producing cytotoxic oxidant species that are particularly active against bacteria with polysaccharide capsules ... [more ▼]

Myeloperoxidase (MPO) is an enzyme located within polymorphonuclear neutrophils capable of producing cytotoxic oxidant species that are particularly active against bacteria with polysaccharide capsules. Pseudomonas aeruginosa (10(6) bacteria per 1ml) are killed within 1 h in vitro by a MPO/H2O2/C1- system (48mU=132ng of MPO). The question arose as to whether human macrophages would acquire cytotoxic activity when loaded with this enzyme. Monocytes were therefore isolated from human blood and cultured for up to ten days to induce maturation to macrophages. These cells lost endogenous MPO within five days while H2O2 production in response to stimulation by phorbol myristate acetate (10(-6)M) decreased to 23% within ten days. On the other hand, their capacity to take up exogenous MPO increased fourfold from day three to day ten. Human macrophages cultured from eight days (when both H2O2 production and MPO uptake were sufficient) were therefore used to study the effects of MPO uptake on cytocidal activity against Pseudomonas aeruginosa. After a 1 h MPO loading period, macrophages (5X10(5) cells per ml) were incubated in the presence of bacteria (0.5 to 2X10(6) bacteria per ml) for 2 h at 37 degrees C. At a bacteria/macrophage ratio of 1, only 34.8+/-7.0% of bacteria survived (compared to killing by non-loaded macrophages), while 74.4+/-9.3% survived at a ratio of 4. From these results, we conclude that loading macrophages with exogenous MPO could enhance their microbicidal activity, suggesting a potentially useful therapeutic application. [less ▲]

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See detailLes reliques sur ordinateur
George, Philippe ULg

in Le médiéviste et l'ordinateur (1996)

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See detailMélanges Pierre Colman
Duchesne, Jean-Patrick ULg

in Art&fact (1996), 15

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See detailSexual differentiation of odor and partner preference in the rat.
Bakker, Julie ULg; Van Ophemert, J.; Slob, A. K.

in Physiology & Behavior (1996), 60(2), 489-94

Previous studies have shown that adult male rats, in which brain estrogen formation was inhibited neonatally by SC administration of the aromatase inhibitor 1,4, 6-androstatriene-3,17-dione (ATD), show an ... [more ▼]

Previous studies have shown that adult male rats, in which brain estrogen formation was inhibited neonatally by SC administration of the aromatase inhibitor 1,4, 6-androstatriene-3,17-dione (ATD), show an altered sexual partner preference. When tested in a three-compartment box, such gonadally intact ATD males approach and mate both with the estrous female and the sexually active male, whereas normal males prefer to approach and mate with the estrous female, avoiding the stimulus male. After castration in adulthood and estradiol treatment, ATD males prefer sexually active males. Similarly treated normal males prefer estrous females, and estrous females prefer to mate with males. In the present study, we asked what stimulus characteristics of active males vs. estrous females determined the different sexual preferences of males, ATD males, and of females. Were they chemosensory cues or more distal cues such as actually seeing and hearing the stimulus animals or the reward of sexual activity with the stimulus animals? Sex differences in preference were evident when animals were given a choice between soiled bedding from estrous females and from sexually active males. ATD and control males spent significantly more time on soiled bedding from estrous females than on soiled bedding from sexually active males. Control females spent significantly more time on soiled bedding from sexually active males than on soiled bedding from estrous females. More distal cues, such as seeing and hearing the stimulus animals, revealed differences in preference between control males and females, but not between ATD and control males. Physical interaction with the stimulus animals was a prerequisite for revealing differences in preference between ATD and control males. Then, the behavior of ATD males was clearly intermediate between that of normal male and female rats. In conclusion, neonatal estradiol is important for the psychosexual development of the male rat. However, the present data suggest that the psychosexual development of the male rat also requires either prenatal estradiol or perinatal testosterone. [less ▲]

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See detailA field observation on the influence of aggressive behaviour on mating success in the European grayling
Poncin, Pascal ULg

in Journal of Fish Biology (1996), 48(4), 802-804

The biggest male grayling present on a spawning area was strongly territorial and developed more aggressive behaviours than smaller males. However, its spawning frequency was similar to that of smaller ... [more ▼]

The biggest male grayling present on a spawning area was strongly territorial and developed more aggressive behaviours than smaller males. However, its spawning frequency was similar to that of smaller males. (C) 1996 The Fisheries Society of the British Isles [less ▲]

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See detailThe development of a European questionnaire for quality of life in patients with vertebral osteoporosis
Lips, P; Agnusdei, D; Caulin, F et al

in Scandinavian Journal of Rheumatology (1996), 25(103), 84-85

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See detailLes Charites à Athènes et dans l’île de Cos
Pirenne-Delforge, Vinciane ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (1996), 9

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See detailCompte rendu de H. GIERSIEPEN, Die Inschriften des Aachener Doms
George, Philippe ULg

in Moyen Age (Le) (1996)

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See detailShedding of the 67-kD laminin receptor by human cancer cells.
Karpatova, M.; Tagliabue, E.; Castronovo, Vincenzo ULg et al

in Journal of Cellular Biochemistry (1996), 60(2), 226-34

The 67-kD laminin receptor (67LR) is a cell membrane-associated molecule exhibiting high affinity for the basement membrane glycoprotein, laminin. While export of the 67LR toward the extracellular matrix ... [more ▼]

The 67-kD laminin receptor (67LR) is a cell membrane-associated molecule exhibiting high affinity for the basement membrane glycoprotein, laminin. While export of the 67LR toward the extracellular matrix has been recently suggested by electron microscopy studies, there is to date no evidence of shedding of the 67LR from cells. Using two monoclonal antibodies directed against the 67LR, we developed a double-determinant radioimmunoassay that demonstrates that the 67LR is released from cancer cells into the culture medium. The shed molecule exhibited the same apparent molecular weight as that of the membrane-associated 67LR, suggesting that no proteolytic cleavage is involved in the process. Furthermore, we demonstrate that the 67LR is not anchored to the membrane through a glycolsyl-phosphatidylinositol bridge. However, the observation that lactose increased the release of 67LR suggests that a lectin-type interaction is involved in the cell membrane association of this laminin binding protein and the cell surface. Interestingly, the released 67LR recovered after HPLC gel filtration was found free as well as associated to high molecular weight complexes. The free 67LR retained its ability to bind to the cell surface. Our study is the first demonstration that the 67LR is effectively shed by cancer cells. The released free 67LR could play an important role in modulating interactions between cancer cells and laminin during tumor invasion and metastasis. [less ▲]

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See detailInfluence of the production of two lipopeptides, Iturin A and Surfactin S1, on oxygen transfer during Bacillus subtilis fermentation
Hbid, Choukri; Jacques, Philippe; Razafindralambo, Hary ULg et al

in Applied Biochemistry and Biotechnology (1996), 57-8

Bacillus subtilis produces three types of lipopeptides: Iturins, Fengycins, and Surfactins. These amphiphilic molecules influence the volumetric oxygen transfer (K(L)a) like chemical surfactant. K(L)a ... [more ▼]

Bacillus subtilis produces three types of lipopeptides: Iturins, Fengycins, and Surfactins. These amphiphilic molecules influence the volumetric oxygen transfer (K(L)a) like chemical surfactant. K(L)a values were from two- to fivefold lower when both Iturin A and Surfactin S1 were coproduced, and from 0.57- to 0.8-fold lower when only Iturin A was produced. The addition of an oxygen vector (n-Dodecane) during fermentation increased K(L)a values (7.5-fold) and biomass production (twofold), and decreased Iturin A and Surfactin S1 production. However, at high stirring conditions and in the presence of n-Dodecane, Iturin A production was improved. [less ▲]

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See detailExpression of the 27,000 mol. wt heat shock protein following kainic acid-induced status epilepticus in the rat.
Plumier, Jean-Christophe ULg; Armstrong, J. N.; Landry, J. et al

in Neuroscience (1996), 75(3), 849-56

Western analysis and immunohistochemistry were used to determine the time-course and the distribution of the 27,000 mol. wt heat shock protein, Hsp27, in rat brain following systemic administration of ... [more ▼]

Western analysis and immunohistochemistry were used to determine the time-course and the distribution of the 27,000 mol. wt heat shock protein, Hsp27, in rat brain following systemic administration of kainic acid. No Hsp27 immunoreactivity was detected in naive control animals or in rats that failed to develop status epilepticus. Hsp27 immunoreactivity was detected as early as 12 h in the parietal cortex, piriform cortex and the hippocampus of rats that developed status epilepticus. The number of cells expressing Hsp27 and the intensity of Hsp27 immunoreactivity were increased 24 h after kainic acid administration. Hsp27 immunoreactivity was still observed seven days post-kainic acid injection. The morphology of the Hsp27-positive cells and double immunofluorescence against Hsp27 and glial fibrillary acidic protein revealed that Hsp27-positive cells were astrocytes. In addition, the distribution of Hsp27 suggested that astrocytic Hsp27 was dependent on excitation-induced metabolic stress rather than the direct effect of kainic acid on astrocytes. [less ▲]

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See detailInfluence des facteurs individuels et de troupeau sur les performances de reproduction bovine
Hanzen, Christian ULg; Houtain, J. Y.; Laurent, Y. et al

in Annales de Médecine Vétérinaire (1996), 140

Through a wide review of the litterature (330 references), the authors have tried to describe the determinant or predisposing effects of factors usually involved in the reproduction problems in beef or ... [more ▼]

Through a wide review of the litterature (330 references), the authors have tried to describe the determinant or predisposing effects of factors usually involved in the reproduction problems in beef or dairy cattle. These factors have been qualified as individual or herd factors. The first ones involve the animal itself like age, genetic, milk production level, dystocia, twinning, perinatal mortality, placental retentio, milk fever, uterine involution, metritis, post-partum ovarian activity. The second ones concern the environnement of the animal i.e. first insemination policy, oestrus detection, insemination time and technic, nutrition, season, stabulation, herd size or management capacity of the farmer. The authors conclude to the multifactorial etiology of the reproduction pathologies. It also appears necessary to develop data collection systems like herd health management programs. Such systems should be able to offer to the practitionner the opportunity to be involved more efficiently in the economic health of the herd using epidemiological tools to study the different implied factors. [less ▲]

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See detailNonspecific airway responsiveness of COPD horses : effects of environmental control
Vandenput, Sandrina ULg; Votion, Dominique ULg; Anciaux, N. et al

in Pflügers Archiv : European Journal of Physiology (1996), 431(6), 324

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See detailObesity in children. Environmental and genetic Aspects
Guillaume, Michèle ULg; Bjorntorp, P.

in Hormone and Metabolic Research. Supplement Series (1996), 28

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See detailOrdovician and Silurian cryptospores and miospores from southeastern Turkey
Steemans, Philippe ULg; Le Hérissé, A; Bozdogan, N

in Review of Palaeobotany and Palynology (1996), 93(1-4), 35-76

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See detailYves Panafieu, Le mystère Buzzati, Liancourt-Saint-Pierre, Y. P., 1995, 303
Curreri, Luciano ULg

in Studi buzzatiani (1996), 1

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See detailInfection of cattle with Yersinia enterocolitica O:9 a cause of the false positive serological reactions in bovine brucellosis diagnostic tests.
Weynants, V.; Tibor, A.; Denoel, P. A. et al

in Veterinary Microbiology (1996), 48(1-2), 101-12

During the last four years, an increasing number of cattle herds were classified positive by brucellosis screening tests in areas of Belgium and France free of the disease. No clinical symptom of ... [more ▼]

During the last four years, an increasing number of cattle herds were classified positive by brucellosis screening tests in areas of Belgium and France free of the disease. No clinical symptom of brucellosis was reported in these animals and no Brucella abortus strains were isolated. After two years, no brucellosis outbreak was registered in all of the herds concerned. On this basis, all the serological reactions observed were classified as false positive. An ELISA using Yersinia Outer membrane Proteins (YOPs) as antigens was developed in order to discriminate between a Yersinia enterocolitica O:9 infection and a Brucella abortus infection. Antibodies against YOPs were detected in sera from Y. enterocolitica O:9 experimentally infected cattle (n = 4) but not in sera from B. abortus experimentally infected cattle (n = 4). In a field study, 66.7% of the 174 serum samples from cattle presenting false positive serological reactions showed anti-YOPs antibodies whereas only 10% of 454 sera, classified negative by the brucellosis screening tests, showed anti-YOPs antibodies. Our results suggest that infections with Y. enterocolitica O:9 may cause false positive reactions in brucellosis testing. [less ▲]

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See detailHeparin-coated Palmaz-Schatz stents in human coronary arteries. Early outcome of the Benestent-II Pilot Study.
Serruys, P. W.; Emanuelsson, H.; van der Giessen, W. et al

in Circulation (1996), 93(3), 412-22

BACKGROUND: The purpose of the Benestent-II Pilot Study was to evaluate the safety of delaying and eliminating anticoagulant therapy in patients receiving a heparin-coated stent in conjunction with ... [more ▼]

BACKGROUND: The purpose of the Benestent-II Pilot Study was to evaluate the safety of delaying and eliminating anticoagulant therapy in patients receiving a heparin-coated stent in conjunction with antiplatelet drugs. METHODS AND RESULTS: The study consisted of three initial phases (I, II, III) during which resumption of heparin therapy after sheath removal was progressively deferred by 6, 12, and 36 hours. In phase IV, coumadin and heparin were replaced by 250 mg ticlopidine and 100 mg aspirin. Of the 207 patients with stable angina pectoris and a de novo lesion in whom heparin-coated stent implantation was attempted, implantation was successful in 202 patients (98%). Stent thrombosis did not occur during all four phases, and the overall clinical success rate at discharge was 99%. Bleeding complications requiring blood transfusion or surgery fell from 7.9% in phase I to 5.9%, 4%, and 0% in the three following phases. Hospital stay was 7.4, 6.1, 7.2, and 3.1 days for the consecutive phases. The restenosis rate for the combined four phases was 13% (15% in phase I, 20% in phase II, 11% in phase III, and 6% in phase IV). The overall rate of reintervention for the four phases was 8.9%. At 6 months, 84%, 75%, 94%, and 92% of the patients of phases I to IV, respectively, were event free. For the four phases, the event-free rate was 86%, which compares favorably with the rate observed in the Benestent-I study (80%; relative risk, 0.68 [0.45 to 1.04]). CONCLUSIONS: The implantation of stents coated with polyamine and end-point-attached heparin in stable patients with one significant de novo coronary lesion is well tolerated, is associated with no (sub)acute stent thrombosis, and results in a favorable event-free survival after 6 months. [less ▲]

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See detailAssessment of the cell-mediated immunity in cattle infection after bovine herpesvirus 4 infection, using an in vitro antigen-specific interferon-gamma assay.
Godfroid, J.; Czaplicki, G.; Kerkhofs, P. et al

in Veterinary Microbiology (1996), 53(1-2), 133-41

The cell-mediated immunity (CMI) following bovine herpesvirus 4 (BHV4) infection has been poorly investigated in cattle. The in vivo response measured by a delayed type of hypersensitivity (DTH) assay has ... [more ▼]

The cell-mediated immunity (CMI) following bovine herpesvirus 4 (BHV4) infection has been poorly investigated in cattle. The in vivo response measured by a delayed type of hypersensitivity (DTH) assay has been reported to be positive in only few animals showing serological evidences of BHV4 infection. We have investigated the CMI following BHV4 infection by an in vitro antigen-specific interferon gamma (IFN-gamma) release assay, as an indicator of an actively acquired immunity to BHV4. Our preliminary results using a partially purified antigen suggest that there was a measurable CMI in 75 out of 168 animals (44.4%) originating from a farm with a clinical history and serological evidences (76.3% seropositivity) of BHV4 infection. If the results of serological tests and BHV4 IFN-gamma test are interpreted in parallel, 81.5% of the animals are classified positive, demonstrating the complementarity of these tests. The specificity of the BHV4 IFN-gamma test was supported by the absence of a measurable CMI in 41 animals originating from a farm with no clinical history or serological evidence of BHV4 infection. In an allied study, we developed a bovine herpesvirus 1 (BHV1) IFN-gamma test. This allowed us to measure the antigen specific IFN-gamma release after stimulation with a mixture of BHV1 and BHV4 antigens. Animals that were classified negative by the BHV4 IFN-gamma test and by the BHV1 IFN-gamma test, were classified negative after stimulation with a mixture of both antigens. Animals that were classified positive by the BHV4 IFN-gamma test or the BHV1 IFN-gamma test, were classified positive after stimulation with a mixture of both antigens. Taken together these results suggest that the in vitro assessment of the CMI after BHV4 infection should be further investigated as a specific and valuable alternative to the DTH assay. [less ▲]

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See detailMutation analysis of the pyruvate dehydrogenase E1 alpha gene in eight patients with a pyruvate dehydrogenase complex deficiency.
Lissens, W.; De Meirleir, L.; Seneca, S. et al

in Human mutation (1996), 7(1), 46-51

Most of the mutations causing deficiency of the pyruvate dehydrogenase (PDH) complex are in the X-linked E1 alpha gene. We have developed a rapid screening method for the detection of mutations in this ... [more ▼]

Most of the mutations causing deficiency of the pyruvate dehydrogenase (PDH) complex are in the X-linked E1 alpha gene. We have developed a rapid screening method for the detection of mutations in this gene using reverse transcription of total RNA, polymerase chain reaction amplification of the whole coding region of the gene and single-strand conformation polymorphism (SSCP) analysis. With this method, we studied eight patients with a PDH complex deficiency, using cultured fibroblasts. In all patients, aberrant SSCP patterns were found and, after sequencing of the corresponding fragments, we were able to identify six new mutations and two mutations already described previously. The mutations are point mutations leading to amino acid substitutions (5) and direct repeat insertions (3). The presence of the mutations was confirmed in genomic fibroblast DNA. The 4 female patients were shown to carry both a normal and a mutated E1 alpha gene. [less ▲]

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