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See detailMechanical behaviour of Lixhe chalk partly saturated by oil and water: experiment and modelling
Collin, Frédéric ULg; Cui, Yu Jun; Schroeder, Christian ULg et al

in International Journal for Numerical and Analytical Methods in Geomechanics (2002), 26(9), 897-924

Two or more different fluids generally saturate chalk in oil reservoir, and therefore its behaviour can be very complicated. In this paper, a constitutive law is proposed for modelling the mechanical ... [more ▼]

Two or more different fluids generally saturate chalk in oil reservoir, and therefore its behaviour can be very complicated. In this paper, a constitutive law is proposed for modelling the mechanical behaviour of a chalk saturated by two non-miscible fluids, water and oil. The effects of the capillary pressure or suction are taken into account. They are considered as an independent variable, as in the Barcelona's basic model developed for unsaturated soils. On the other hand, internal friction and pore collapse are modelled as independent mechanisms. The determination of the parameters is based on triaxial and oedometer tests. Finally, in order to validate the model, predictions are compared with experimental results of water-flooding test. Copyright (C) 2002 John Wiley Sons, Ltd. [less ▲]

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See detailMolecular characterization of a specific thiamine triphosphatase widely expressed in mammalian tissues
Lakaye, Bernard ULg; Makarchikov, Alexander F; Antunes, Adelio F et al

in Journal of Biological Chemistry (2002), 277(16), 13771-13777

Thiamine triphosphate (ThTP) is found at low concentrations in most animal tissues, and recent data suggest that it may act as a phosphate donor for the phosphorylation of some proteins. In the mammalian ... [more ▼]

Thiamine triphosphate (ThTP) is found at low concentrations in most animal tissues, and recent data suggest that it may act as a phosphate donor for the phosphorylation of some proteins. In the mammalian brain, ThTP synthesis is rapid, but its steady-state concentration remains low, presumably because of rapid hydrolysis. In this report we purified a soluble thiamine triphosphatase (ThTPase; EC 3.6.1.28) from calf brain. The bovine ThTPase is a 24-kDa monomer, hydrolyzing ThTP with virtually absolute specificity. Partial sequence data obtained from the purified bovine enzyme by tandem mass spectrometry were used to search the GenBank(TM) data base. A significant identity was found with only one human sequence, the hypothetical 230-amino acid protein MGC2652. The coding regions from human and bovine brain mRNA were amplified by reverse transcription-PCR, cloned in Escherichia coli, and sequenced. The human open reading frame was expressed in E. coli as a GST fusion protein. Transformed bacteria had a high isopropyl-beta-D-thiogalactopyranoside-inducible ThTPase activity. The recombinant ThTPase had properties similar to those of human brain ThTPase, and it was specific for ThTP. The mRNA was expressed in most human tissues but at relatively low levels. This is the first report of a molecular characterization of a specific ThTPase. [less ▲]

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See detailA performance study of RSVP with proposed extensions
Mathy, Laurent ULg; Hutchison, D.; Schmid, S. et al

in Computer Communications (2002), 25(18), 1782--1798

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See detailLa mesure de la pression artérielle : écueils et chausse-trapes
Rorive, Georges ULg; Dubois, Bernard ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2002), 57(5), 250-252

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis ... [more ▼]

La mesure de la pression artérielle est probablement l'acte médical le plus souvent réalisé et certainement un des moins fiables. L'introduction de la mesure ambulatoire de la pression artérielle a permis d'identifier l'importance de l'effet consultatio et, par là, de définir l'hypertension de "la blouse blanche". Celle-ci se définit comme une pression artérielle pathologique à la consultation et strictement normale en dehors. Si on la définit de cette manière, cette pathologie ne s'accompagne pas d'une augmentation de la fréqunce des affections cardiovasculaires. Chez un tiers des patients, cependant, elle évolue vers des formes plus sévères de l'hypertension. [less ▲]

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See detailPharma clinics. Comment je traite ... un herpes labial récurrent.
Petit, L.; Braham, C.; Nikkels, Arjen ULg et al

in Revue Médicale de Liège (2002), 57(2), 67-71

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent ... [more ▼]

Recurrent herpes labialis is a frequent disorder. It occurs following the reactivation of the Herpesvirus (HSV1 and more rarely HSV2) inside the Gasser ganglion. Treatment and prevention of recurrent labial herpes are targeted by specific antiviral agents. Spectacular benefits obtained in the immunocompromised patients are less convincing in otherwise healthy subjects. Other prospective ways of therapy are under consideration, including lipopeptides and physical means aiming at modifying the cutaneous pH. [less ▲]

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See detailApercu nosologique du spectre des histiocytoses cutanees. Plus ca change, plus c'est la meme chose.
Quatresooz, Pascale ULg; Hermanns-Lê, Trinh ULg; Arrese Estrada, Jorge ULg et al

in Revue Médicale de Liège (2002), 57(11), 715-8

Histiocytes belong to distinct groups of cells. Similarly, histiocytoses represent some pathologic expressions of the various histiocyte lineages recognized by their distinct phenotypes. The recognition ... [more ▼]

Histiocytes belong to distinct groups of cells. Similarly, histiocytoses represent some pathologic expressions of the various histiocyte lineages recognized by their distinct phenotypes. The recognition of four major histiocytosis types relies on the distinction between monocytes-macrophages, dermal dendrocytes, Langerhans cells and the so-called indeterminate cells. Each of these groups exhibits a distinctive clinical and histological presentation. The risk of internal involvement, the prognosis and therapy are different as well. The diagnostic mainly relies on the clinico-pathologic assessment, and more particularly on the combination of histological, immunohistochemical and ultrastructural examinations. [less ▲]

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See detailLa mémoire des morts à Stavelot-Malmedy. Des origines au XIIe siècle
George, Philippe ULg

in Malmedy Folklore (2002)

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See detailEconomic evaluation of chronic hepatitis C treatment by interferon-ribavirin combination therapy in Belgium
Delwaide, Jean ULg

in Acta Gastro-Enterologica Belgica (2002), 65(4), 233-236

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response ... [more ▼]

With present treatments for chronic hepatitis C by the combination of interferon alpha and ribavirin, it is possible to obtain a sustained viral response in a large number of patients. This viral response is associated with long-term disappearance of the C virus, improvement of histology, improvement in quality of life and, most than likely, a reduction in the risk of premature death or infection-linked complications. This therapy is, however, expensive and the number of potentially treatable patients is high in view of the relatively high prevalence of the disease in the population. An economic evaluation is thus indispensable in order, on the one hand, to assess the cost-effectiveness ratio of the treatment (i.e. the extra cost to be paid for obtaining the greater effectiveness provided by the therapeutic combination in comparison with absence of treatment or treatment by interferon alone), and, on the other hand, to estimate practically the global cost of treatment for Belgium (i.e. the annual expense for society according to the number of patients treated per year). [less ▲]

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See detailComment on "Strong vortex liquid correlation from multiterminal measurements on untwinned YBa2Cu3O7-delta single crystals"
Maiorov, B.; Silhanek, Alejandro ULg; de la Cruz, F. et al

in Physical Review Letters (2002), 88(13),

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See detailEntre Italie et Pays-Bas méridionaux. Le « Libro de memoria » de la famille Cassina. 1576-1650.
Moreno, Paola ULg

in Studi e Problemi di Critica Testuale (2002)

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See detailShort- and long-term advantages of an alternative ontogenetic pathway
Denoël, Mathieu ULg; Hervant, F.; Schabetsberger, R. et al

in Biological Journal of the Linnean Society (2002), 77(1), 105-112

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body ... [more ▼]

We documented hypotheses on the evolution of developmental heterochronies by estimating short- and long-term advantages of alternative morphs. In this respect, we compared food energy intakes and body condition between paedomorphic and metamorphic Alpine newts (Triturus alpestris, Caudata, Amphibia) in four populations. Because we found a strong correlation between fat reserves and body condition, we used this last parameter as an indicator of long-term gains. In all studied sites, paedomorphic females showed higher body condition than metamorphic ones. Paedomorphic males were also at advantage in two populations. Paedomorphs exhibited higher energy intakes than metamorphs in two populations and similar gains in two others. Our results support unifying theories that predict the occurrence of facultative paedomorphosis in varied habitats as paedomorphs exhibited better energy balance than metamorphs. This work shows the need for considering integrative parameters such as body condition in the comparative study of performances when studying developmental heterochronies. (C) 2002 The Linnean Society of London, Biological Journal of the Linnean Society, 2002, 77, 105-112. [less ▲]

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See detailLa recherche scientifique en Hautes-Fagnes
Streel, Maurice ULg

in Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Sciences (2002), XIII(1-6), 55-65

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See detailPharma clinics. Le médicament du mois. L'imiquimod (Aldara): un immunomodulateur pour la peau.
Hermanns-Lê, Trinh ULg; Nikkels, Arjen ULg; Uhoda, Isabelle et al

in Revue Médicale de Liège (2002), 57(2), 116-8

Imiquimod is the first drug of a new therapeutic class encompassing cutaneous immune response modifiers. This molecule induces the synthesis and release of macrophage-related cytokines. It boosts some ... [more ▼]

Imiquimod is the first drug of a new therapeutic class encompassing cutaneous immune response modifiers. This molecule induces the synthesis and release of macrophage-related cytokines. It boosts some local immune responses. These properties are used to treat cutaneous viral condylomas. Other prospective therapeutic goals are presently scrutinized. [less ▲]

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See detailUse of Anesthesia Simulator
Pendeville, Philippe; Mayne, Alain; LARBUISSON, Robert ULg et al

in Benelux quaterly journal on automatic control (2002), 43(2), 17-19

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See detailAg/SiO2 and Cu/SiO2 cogelled xerogel catalysts for benzene combustion and 2-butanol dehydrogenation
Lambert, Stéphanie ULg; Tcherkassova, Natalia; Cellier, Caroline et al

in Studies in Surface Science and Catalysis (2002), 143

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See detailL’authenticité iconographique des portails occidentaux de la cathédrale de Strasbourg
Van den Bossche, Benoît ULg

in Bulletin de la Cathédrale de Strasbourg (2002), 15

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See detailL'image du mois. Sclérose tubéreuse de Bourneville.
Garcia, Roy; Arrese Estrada, Jorge ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(7), 425-7

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See detailInventories and Maps: Cognitive Ways of Framing the Nature Policies in Europe
Mougenot, Catherine ULg; Remy, Elisabeth

in Journal of Environmental Policy & Planning (2002), 4(4), 313-322

Since the Earth Summit in Rio, declining biodiversity has become a subject of general concern for many countries. To counter these negative trends, government nature policies in Europe at least are now ... [more ▼]

Since the Earth Summit in Rio, declining biodiversity has become a subject of general concern for many countries. To counter these negative trends, government nature policies in Europe at least are now thought out primarily in terms of networks. They concern new areas outside nature reserves, new players and new management strategies. Consequently, these policies should themselves become the subject of new public debate. Our study concerns the analysis of the forms used to collect the data required to set up the European Union's Natura 2000 network and maps drawn as part of the Council of Europe's Pan-European Ecological Network strategy. The aim of this article, which takes the perspective developed by the sociology of science, will be to show how the forms and maps used in these new nature policies produce knowledge that precedes policy discussions to search for the best possible socio-political compromises. In other words, the knowledge that is collected in and by means of these documents, forms and maps offers a cognitive way of framing the subsequent public debates. [less ▲]

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See detailBelgian peer review experience on the Achille's heel in haemodialysis care: vascular access
Theelen, Bernadette ULg; Rorive, Georges ULg; Krzesinski, Jean-Marie ULg et al

in EDTNA/ERCA Journal (2002), 28(4, Oct-Dec), 164-166

AIMS: In order to improve the supervision and to evaluate the quality of care in dialysis units, a national project was promoted as a Peer Review. It consisted of systematic, continuous and critical ... [more ▼]

AIMS: In order to improve the supervision and to evaluate the quality of care in dialysis units, a national project was promoted as a Peer Review. It consisted of systematic, continuous and critical evaluation of the care and the application of international guidelines and compared the reality of care with standards. METHOD: The first chart consisted of the evaluation of infectious episodes of vascular access. This point is particularly relevant since infection represents the second cause of mortality in haemodialysis. A questionnaire concerning each patient was designed. Questions concerned the description of vascular access and the related infectious events. Each questionnaire included 21 items. The project involved 29 dialysis centres, 1,644 patients and 1,775 vascular accesses. The database included 90,525 data. RESULTS: Among the 29 centres, the native arteriovenous fistula (AVF) is the first choice (67.5%) in vascular access, but the proportion of AVF decreases with age contrary to the catheter, which is more frequently chosen, in older patients. Independent of age, 20% of hospitalisations are among patients with catheters and only 7% among patients with AVF. The RR (relative risk) of being hospitalised (any complication of vascular access) is 1.68 for patients with catheters compared to patients with AVF. The rate of infections does not increase with age but is higher for patients with catheters (RR = 2.26). The number of infections appears to be dependent on the staphylococcus aureus carriage in the year. CONCLUSIONS: This first step allows each centre to compare itself to others in an anonymous way. This approach should lead to specific recommendations to improve the quality of care in dialysis units. [less ▲]

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See detailPollution chimique de l'environnement et risque toxique pour l'homme. Le rôle particulier des dérivés pesticides organochlorés
Charlier, Corinne ULg; Plomteux, Guy ULg

in Annales de Biologie Clinique (2002), 60(1, Jan-Feb), 37-46

There is an increasing concern about environmental exposure to multiple chemicals and adverse changes in reproductive development, function, or behaviour in wildlife. The major group of environmental ... [more ▼]

There is an increasing concern about environmental exposure to multiple chemicals and adverse changes in reproductive development, function, or behaviour in wildlife. The major group of environmental chemicals, such as organochlorine pesticides, polychlorinated biphenyls (PCBs) and other xenoestrogens are currently known to have estrogenic effects in vertebrates or fishes. Recent studies suggest that past exposure to such estrogenic compounds may affects the risk of developing breast cancer, precocious puberty, or impaired fertility in man. [less ▲]

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See detailGeochemistry of bitter brines in the Salar de Coipasa - Bolivia
Lebrun, Vincent; Pacosillo, Pedro; Gutierrez, Jorge et al

in Aardkundige Mededelingen (2002), 12

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See detailRunoff control of soil degassing at an active volcano. The case of Piton de la Fournaise, Reunion Island
Toutain, J. P.; Baubron, J. C.; François, Louis ULg

in Earth And Planetary Science Letters (2002), 197(1-2), 83-94

Airborne atmospheric and in-situ soil gas analyses demonstrate that distal gas leaks are non-existent at Piton de la Fournaise (PF) despite frequent eruptions. Airborne traverses made at a constant ... [more ▼]

Airborne atmospheric and in-situ soil gas analyses demonstrate that distal gas leaks are non-existent at Piton de la Fournaise (PF) despite frequent eruptions. Airborne traverses made at a constant altitude indicated that no detectable large-scale CO2 degassing occurs from the volcano. In-situ soil gas traverses (CO2, He-4, Rn-222) across the active riftzones, the summit crater and the caldera rims, show both a lack of positive anomalies and evidence of strong depleted concentrations for He and CO2 with respect to air. Depletions in soil He is explained by intense rain water infiltration. A more unexpected result lies in the very low CO2 concentrations (down to 92 ppm) in bare soils in the summit region. Such a depletion was not previously reported and is attributed to considerable basalt weathering operating as the result of huge runoff. A model has enabled both the runoff and the CO2 consumption occurring within the basaltic layers to be calculated. Data obtained are consistent with values expected from large-scale erosion models and with the local calculated diffusive flux of CO2 in soils. The huge runoff, together with the basaltic lithology of the volcano, are found to be the main factor controlling the soil gas signatures at PF. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailAssessment of milk yield losses and subclinical mastitis risk factors using bulk milk somatic cell counts in dairy herds
Mtaallah, Brahim; Oubey, Zied; Hammami, Hedi ULg

in Revue de Médecine Vétérinaire (2002), 153(4), 251-260

A prospective study, involving 21 selected dairy farms in north of Tunisia, was conducted to asses the loss of milk production due to high levels bulk tank somatic cell count and to find some relationship ... [more ▼]

A prospective study, involving 21 selected dairy farms in north of Tunisia, was conducted to asses the loss of milk production due to high levels bulk tank somatic cell count and to find some relationship between risk factors and subclinical mastitis. We found that the mean of bulk milk somatic cell count was 626 103 cell/ml. Using a simple statistical model, the average loss of milk due to levels bulk tank somatic cell count was 524 kg per cow per year. Using method of mean comparisons, risk factors associated to high levels bulk tank somatic cell count was: Livestock farming risk factors : inadequacy bedding area; inadequacy cleaning bedding and scrapping area. Milking risk factors : washing teat with a shower no adjustable flow and without wipe with individuel towel milk shift work above five per cow-herd; no stripping squirts of milk before milking; milking healthy and mastitis cows at the same time; no teat dipping. [less ▲]

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See detailRelationship between markers of blood oxidant status and physiological variables in healthy and heaves-affected horses after exercise
Kirschvink, Nathalie; Art, Tatiana ULg; de Moffarts, Brieuc et al

in Equine Veterinary Journal. Supplement (2002), 34

Exercise-induced oxidative stress is investigated as a potential performance-limiting factor in human sports medicine. Therefore, the present study aimed to assess whether physiological variables that ... [more ▼]

Exercise-induced oxidative stress is investigated as a potential performance-limiting factor in human sports medicine. Therefore, the present study aimed to assess whether physiological variables that change with exercise intensity were correlated with blood oxidant markers in healthy and heaves-affected horses. Seven healthy horses, 8 heaves-affected in remission and 7 heaves-affected in crisis performed a standardised exercise test (SET) of stepwise increasing intensity. Variables monitored during exercise were heart rate (HR), venous plasma lactate (LA), packed cell volume (PCV) and arterial oxygen tension (PaO2). Oxidant markers (uric acid [UA], 8-iso-PGF2alpha and reduced [GSH] and oxidised glutathione [GSSG]) were analysed in venous peripheral blood sampled at rest (R), at peak-exercise intensity (Emax), 15 (E15) and 60 (E60) min after SET. There was a significant effect of heaves on oxidant markers and, therefore, correlation analyses between physiological variables and oxidant markers were performed separately per horse group. In healthy horses, UA analysed at Emax was positively correlated with LA. Furthermore, GSH analysed at Emax and E15 was positively correlated with PaO2. In healthy and heaves-affected horses in remission, GSH and GSSG determined at Emax were negatively correlated with HR. There was no significant correlation between 8-iso-PGF2alpha and physiological variables. In conclusion, a correlation between the physiological response to exercise and some oxidant markers exists in healthy horses. However, in heaves-affected horses the blood oxidant status is probably more dependant on airway disease than on exercise. Future studies should be undertaken to assess whether antioxidant supplementation might positively influence the oxidant-antiodidant balance in exercising horses. [less ▲]

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See detailSmearing scheme for finite-temperature electronic-structure calculations
Verstraete, Matthieu ULg; Gonze, X.

in Physical Review. B : Condensed Matter (2002), 65

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See detailPeritoneal Tuberculosis in an African Immigrant
Milicevic, Mladen ULg; Boverie, J. H.; Dondelinger, R. F.

in JBR-BTR : Journal Belge de Radiologie - Belgisch Tijdschrift voor Radiologie (2002), 85(3, Jun-Jul), 140-1

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See detailLa périurbanisation résidentielle en Belgique à la lumière des contextes suisse et danois: enracinement, dynamiques centrifuges et régulations collectives
Halleux, Jean-Marie ULg; Bruck, L.; Mairy, N.

in Belgeo (2002), (4), 333-354

Par rapport à ses voisins européens, la Belgique apparaît marquée par une périurbanisation à la fois plus importante et plus éclatée, ce dont résultent sans conteste de nombreux accrochages par rapport ... [more ▼]

Par rapport à ses voisins européens, la Belgique apparaît marquée par une périurbanisation à la fois plus importante et plus éclatée, ce dont résultent sans conteste de nombreux accrochages par rapport aux principes stratégiques du développement durable. Le présent article se propose d’étudier les causes de l’éclatement urbain qui affecte le territoire belge à la lumière d’une comparaison avec la Suisse et le Danemark, deux pays réputés pour avoir mis sur pied des politiques relativement efficaces de lutte contre l’étalement urbain. De cette comparaison appréhendée via les trois thématiques de la politique foncière, de la production immobilière résidentielle et du choix clair de la Belgique en faveur de la mobilité voiture, c’est l’enracinement profond de la périurbanisation belge qui apparaît. L’éclatement urbain qui y affecte le territoire s’intègre, en effet, dans une grappe de facteurs explicatifs où s’entremêlent l’influence du milieu naturel, des réticences séculaires pour les modes de vie urbains, une faible conscientisation aux enjeux de la planification physique et des choix politiques rémanents ayant fortement contribué au renforcement des dynamiques centrifuges. [less ▲]

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See detailSubclinical speckled perifollicular melanosis of the scalp.
Petit, Ludivine; Saint Leger, Didier; Loussouarn, Genevieve et al

in European Journal of Dermatology (2002), 12(6), 565-8

Based on the clinical presentation of some skin pigmentation disorders it is thought that a bicompartmental functional system exists in the epidermal melanocyte population. It corresponds to the ... [more ▼]

Based on the clinical presentation of some skin pigmentation disorders it is thought that a bicompartmental functional system exists in the epidermal melanocyte population. It corresponds to the perifollicular and interfollicular compartments, respectively. The present study was undertaken looking for the presence of such a system on scalp unaffected by pigmentary disorders. The scalps of 100 men with incipient to severe androgenic alopecia were examined using a videocamera equipped with an internal ultraviolet light-emitting unit. The face, trunk and limbs were similarly examined in 45 of these adults and in 13 children of both sexes. In 92 men, a subclinical hypermelanosis was found as a speckled pattern centered on every single follicle. With increasing baldness severity, another epidermal hyperpigmentation pattern involving the interfollicular area was superimposed to the perifollicular pattern. These stereotyped patterns of subclinical melanoderma were also disclosed on the face of adults, but not in children. In addition, the spotty perifollicular pattern was discrete or not apparent on the other parts of the body. It is concluded that the perifollicular subclinical melanotic pattern is a regional characteristic of cephalic skin, perhaps related to the local production of melanocortins, particularly alpha-MSH by the pilosebaceous unit. [less ▲]

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See detailAcarbose for type 2 diabetes prevention.
Scheen, André ULg

in Lancet (2002), 360(9344), 15161517

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See detailCambios en la participación política de los inmigrantes en la región de Bruselas capital. Elecciones de octubre de 2000
Martiniello, Marco ULg; Jacobs, Dirk; Rea, Andrea

in Revista Migraciones (2002), 11

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See detailBright Spots and the Question of Hafting
Rots, Veerle ULg

in Anthropologica et Praehistorica : Bulletin de la Société Royale Belge d'Anthropologie et de Préhistoire (2002), 113

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See detailBiocontrol Of Listeria Monocytogenes In A Model Cultured Milk (Lben) By In Situ Bacteriocin Production From Lactococcus Lactis Ssp Lactis
Benkerroum, N.; Ghouati, Y.; Ghalfi, H. et al

in International Journal of Dairy Technology (2002), 55(3),

Bacteriocin-producing (Bac+) Lactococcus lactis ssp. lactis CCMM/IAV/BK1 isolated from traditional lben was used in the preparation of lben from pasteurized milk to assess its potential inhibitory ... [more ▼]

Bacteriocin-producing (Bac+) Lactococcus lactis ssp. lactis CCMM/IAV/BK1 isolated from traditional lben was used in the preparation of lben from pasteurized milk to assess its potential inhibitory activity against Listeria monocytogenes ATCC 7644. Production of bacteriocin (arbitrary units, AU) in MRS broth fortified with yeast extract (MRSY) in a fermentor under controlled and uncontrolled pH conditions was also investigated. This Bac+ strain yielded about 35 times more bacteriocin when the pH was maintained constant at 6.5 than under varying pH conditions. To test the effect of in situ bacteriocin production against L. monocytogenes, lben was made from cow's milk artificially contaminated with approximately 107 cfu/mL and fermented with a mixed mesophilic starter culture consisting of the lactococcal Bac+ organism and Lc. lactis ssp. lactis biovar diacetylactis 66, a diacetyl-producing strain, in a ratio of 1 : 1. Numbers of L. monocytogenes were monitored during fermentation and storage of lben at refrigeration temperature (c. 7°C) for up to 6 days. Performances of the Bac+ starter were compared to those of an isogenic Bac- derivative strain obtained from the Bac+ starter by curing with ethidium bromide. The results showed that the amount of L. monocytogenes decreased to below the detectable level in a 1-mL sample within 24 h of storage at 7°C in lben fermented with the Bac+ starter culture. On the contrary, L. monocytogenes survived for 6 days of storage at 7°C in lben made with the Bac- starter. The Bac+ wild strain of the starter studied could be adequately used to produce lben or similar indigenous fermented milks of improved hygienic quality on an industrial scale. Alternatively, it could be used as an adjunct in minimally processed products or in products obtained from raw milk to add a safety factor. [less ▲]

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See detailPrevention de l'apparition du diabete de type 2 par l'inhibition du systeme renine-angiotensine.
Scheen, André ULg

in Revue Médicale de Liège (2002), 57(7), 449-52

Type 2 diabetes mellitus and arterial hypertension are part of the insulin resistance syndrome. Besides a metabolic component, insulin resistance has also an haemodynamic component, especially in relation ... [more ▼]

Type 2 diabetes mellitus and arterial hypertension are part of the insulin resistance syndrome. Besides a metabolic component, insulin resistance has also an haemodynamic component, especially in relation with an endothelial dysfunction. Some studies suggested that inhibitors of angiotensin converting enzyme can improve insulin sensitivity. Interestingly enough, three clinical trials recently reported concordant results showing that the inhibition of the renin-angiotensin system significantly reduces the risk of developing type 2 diabetes in patients at high risk of vascular complications, essentially with hypertension: the CAPPP trial with captopril (-14%, p = 0.39), the HOPE study with ramipril (-34%, p < 0.001) and the LIFE study with losartan (-25%, p < 0.001). However, these observations could be criticized because such a protective effect was only considered as a secondary endpoint in these studies. Two large prospective, controlled, randomized, double-blind trials are ongoing to specifically confirm this interesting hypothesis, one with ramipril and the other with valsartan. [less ▲]

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See detailProlégomènes à l'étude de la Schola du Trajan à Ostie.
Morard, Thomas ULg; Wavelet, David

in Mélanges de l'Ecole Française de Rome. Italie et Méditérranée (2002), 114(2), 759-815

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See detailLe Pr J.-M. Krzesinski (CHU sart Tilman, ULg) a sélectionné pour vous...
Krzesinski, Jean-Marie ULg

in Tempo Médical (2002), 240

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See detailImpact of closed habitat on the entomological diversity and abundance in carrot open fields
Colignon, Pierre; Gaspar, Charles; Haubruge, Eric ULg et al

in Med. Fac. Landbouw. Univ. Gent (2002), 67(3), 481-486

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See detailMise au point d'un modèle cartographique pour la description des stations forestières en Ardenne belge.
Claessens, Hugues ULg; Lejeune, Philippe ULg; Cuvelier, M. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(4), 209-220

The paper presents an original method dealing with the forest site types delineation. The suggested method consists in integrating a typological key in a GIS aiming at producing a thematic map that ... [more ▼]

The paper presents an original method dealing with the forest site types delineation. The suggested method consists in integrating a typological key in a GIS aiming at producing a thematic map that describes forest site types. Data used are the soil map of Belgium (digitized at the scale 1:20,000) and a digital elevation model built from a topographic map (scale 1:10,000). The typological key is mainly based on the methodology used by Thill et al. (1988) in the site types system for central Ardenne, the potential vegetation map of Sougnez and Dethioux (1975) and the ecoregion map of Delvaux and Galoux (1962). In that respect, site types are closely linked to the soil map and the phytosociological classification. So, they can be connected to the afforestation guide and different phytosociological and autecological studies concerning forest species. It is then possible to map the potential habitats or the site potentialities related to tree species. The key is valid for the Ardenne ecoregion located in Southern Belgium (elevation higher than 300 m). It has to be validated through an intensive use in the field, taking into account its imprecision linked to the types of collected data, chieffly those being digitized. The integration of such a tool in a SIG can be considered as an original way in terms of integrated forest management or forest sites description in the context of the project “Natura 2000” launched by the European Union. The study has been carried out within the framework of an experimental integrated management project concerning the Saint-Hubert forest (17,000 ha). [less ▲]

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See detailThe Offense of Hooliganism and the Moral Dimension of China's Pursuit of Modenrity
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2002), Vol. XVIII

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See detailTraite des êtres humains : un coup de frein à l'application de l'article 77bis de la loi du 15 décembre 1980 ?
Monville, Pierre ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailLa guerre et la médecine d'une culture de paix. 4. Synopsis des armes nucléaires.
Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(2), 107-12

The nuclear weapons have a terrifying power of devastation. A civilian nuclear accident has its own dramatic consequences. Both situations are, however, totally distinct with regard to medical ... [more ▼]

The nuclear weapons have a terrifying power of devastation. A civilian nuclear accident has its own dramatic consequences. Both situations are, however, totally distinct with regard to medical consequences. The Gulf war and Balkan war syndromes might be in part caused by uranium used in conventional amunitions. The risk of nuclear terrorism is an emerging eventuality. [less ▲]

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See detailAromatic Side-Chain Interactions In Proteins. I. Main Structural Features
Thomas, Annick ULg; Meurisse, R.; Charloteaux, Benoît ULg et al

in Proteins-Structure Function and Genetics (2002), 48(4), 628-34

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency ... [more ▼]

In a data set of 593 nonhomologous proteins from the PDB, we have analyzed the pairing of phenylalanine, tyrosine, tryptophan, and histidine residues with their closest aromatic partner. The frequency distribution of the shortest interatomic distance of partners is bimodal with a sharp peak at approximately 3.8 A and a wider one at a longer distance. Only the 3.8 A peak corresponds to direct ring-ring interactions thus aromatic pairs. The aromatic pairs were separated into two classes, near-sequence pairs and far-sequence pairs. Near sequence pairs stabilize local structure, and far-sequence pairs stabilize tertiary structure. Far-sequence pairs (74% of all pairs) mainly bridge two beta-strands, followed by pairs that bridge a beta-strand and a helix, and pairs that bridge a beta-strand and a random coil structure. Pairs that bridge helices are rare. The secondary structure of the near-sequence pairs depends on the partner distance in the sequence. When the partners are 1, 3, or 4 residues apart in the sequence, pairs are mostly found in helical structures. When the partners are two apart, pairs are mostly found in the same beta-strand. Analysis of the frequency of near sequence pairs supports the hypothesis that aromatic pairing occurs after, rather than before, the formation of secondary structures. [less ▲]

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See detailRépartition des arbres et des volumes par classes de grosseur dans les peuplements de pin d'Alep (Pinus halepensis Mill.) en Tunisie
Sghaier, T.; Palm, Rodolphe ULg

in Annals of Forest Science (2002), 59(3), 293-300

A study of the number and volume of trees by girth classes for Aleppo pine (Pinus halepensis Mill.) in Tunisia carried out using data collected from 348 temporary plots of 4 ares. The standard deviation ... [more ▼]

A study of the number and volume of trees by girth classes for Aleppo pine (Pinus halepensis Mill.) in Tunisia carried out using data collected from 348 temporary plots of 4 ares. The standard deviation, the FISHER coefficient and PEARSON coefficient for the girth distribution were calculated for each plot and related to age, dominant height and mean plot circomference. The resulting relationships were used to estimate the parameters of the girth distribution for each theoretical stand corresponding to one row of the yield tables that were establied from the same plots. The probability density function relative to PEARSON's type I distribution was determined for each theoretical stand. According to this function of density, distribution tables giving the number and the volume of trees (in percent) by girth classes of 10 cm were drawn up. [less ▲]

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See detailComparison of plasma cardiac troponins T and I in chronically hemodialyzed patients in relation to cardiac status and age
Chapelle, Jean-Paul ULg; Dubois, Bernard ULg; Bovy, Christophe ULg et al

in Clinical Chemistry & Laboratory Medicine (2002), 40(3), 240-245

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See detailL'image du mois. Une onychopathie ponctuée en dé a coudre.
Perotti-Abad, M. J.; Arrese Estrada, Jorge ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(3), 129-30

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See detailAssesment of the situation, three years later, on 'the Belgian Dioxin Crisis'. Probable impact on the health of the Belgian population
Focant, Jean-François ULg; Pirard, Catherine ULg; Douny, Caroline ULg et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 321-327

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on ... [more ▼]

In January 1999, Belgium encounters an accidental contamination of the food chain, which was named "the Belgian Dioxin Crisis". The aim of the present review is to estimate the impact of this crisis on public health. Currently, it does not really exist any exhaustive epidemiological study. Various scientific studies actually report somewhat conflicting results. As an example, concerning the population living in Wallonia, recorded dioxin levels are not higher than background levels reported for other industrialized countries, despite the 1999 "dioxin crisis". Conversely, based on levels measured in foodstuffs collected by the end of the crisis period, the dioxin body burden of potential consumers would have increased in the range of 40 to 75 %. The real impact of this crisis on consumers' health could thus only be estimated through well structured epidemiological campaigns. [less ▲]

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See detailAtteintes neuromusculaires aiguës de réanimation (ANMAR) : étude électrophysiologique prospective de 56 cas
BARTSCH, Valérie ULg; TOMASELLA, Marco ULg; Zeevaert, Bernard et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2002)

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See detailGenetic variation and evolution in the genus Apodemus (Muridae : Rodentia)
Filippucci, M. G.; Macholan, M.; Michaux, Johan ULg

in Biological Journal of the Linnean Society (2002), 75(3), 395-419

Genetic variation was studied using protein electrophoresis of 28-38 gene loci in 1347 specimens of Apodemus agrarius, A. peninsulac, A. flavicollis, A. sylvaticus, A. alpicola, A. uralensis, A. cf ... [more ▼]

Genetic variation was studied using protein electrophoresis of 28-38 gene loci in 1347 specimens of Apodemus agrarius, A. peninsulac, A. flavicollis, A. sylvaticus, A. alpicola, A. uralensis, A. cf. hyrcanicus, A. hermonensis, A. m. mystacinus and A. in. epimelas, representing 121 populations from Europe, the Middle East, and North Africa. Mean values of heterozygosity per locus for each species ranged from 0.02 to 0.04. Mean values of Nei's genetic distance (D) between the taxa ranged from 0.06 (between A. flavicollis and A. alpicola) to 1.34 (between A. uralensis and A. agrarius). The highest values of D were found between A. agrarius and other Apodemus species (0.62-1.34). These values correspond to those generally observed between genera in small mammals. Our data show that A. agrarius and A. peninsulae are sister species, well-differentiated from other taxa. High genetic distance between A. m. mystacinus and A. m. epimelas leads us to consider them distinct species and sister taxa to other Western Palaearctic species of the subgenus Sylvaemus. The data also suggest a recent separation of members of the latter group from a common ancestor, and subsequent rapid radiation, making it difficult to infer phylogenetic relationships. Some taxonomic implications of the results are discussed further. (C) 2002 The Linnean Society of London. [less ▲]

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See detailAdult mullerian duct or utricle cyst: clinical significance and therapeutic management of 65 cases.
Coppens, Luc ULg; Bonnet, Pierre ULg; Andrianne, Robert ULg et al

in Journal of Urology (The) (2002), 167(4), 1740-4

PURPOSE: We define guidelines for the exploration and treatment of adult mullerian duct cysts. MATERIALS AND METHODS: From January 1988 through September 1999 a diagnosis of enlarged prostatic utricle was ... [more ▼]

PURPOSE: We define guidelines for the exploration and treatment of adult mullerian duct cysts. MATERIALS AND METHODS: From January 1988 through September 1999 a diagnosis of enlarged prostatic utricle was made in 65 adults based on transrectal ultrasound findings. Echographic criteria to define simple versus complicated cysts were detailed. We reviewed the clinical presentation, diagnostic modalities, indications for invasive procedures and postoperative outcome. RESULTS: The usual clinical presentations were hematospermia in 40% of cases, other ejaculatory disturbances in 20%, recurrent testicular or pelviperineal pain in 33%, lower urinary tract irritation symptoms in 25%, lower urinary tract infection in 18.5%, male infertility in 12% and incidental finding in 18.5%. Cyst dimensions did not influence the indication for invasive procedures, which were performed in only 27 of the 65 patients (41.5%) to treat disabling symptoms in 28% and obstructive infertility in 5%, and investigate complicated cysts on transrectal ultrasound in 6%. These procedures included transperineal or transrectal puncture in 9 patients, simple endoscopic section of the utricle meatus in 12 and large marsupialisation in 6. Complete and sustained cure was noted in half of the patients treated with cyst puncture only, although echographic relapse was the rule. Endoscopic procedures definitely improved or cured 82% of the patients at a mean followup of 51 months, during which neither early nor late complications were noted. CONCLUSIONS: Since almost 60% of adults diagnosed with a mullerian duct cyst did not experience any cyst related symptoms or ejaculatory-fertility impairment, we recommend that investigation and/or treatment should only be done in symptomatic or infertile patients. [less ▲]

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See detailUncoupling protein and alternative oxidase of Dictyostelium discoideum: occurrence, properties and protein expression during vegetative life and starvation-induced early development.
Jarmusszkiewicz, W.; Behrendt, M.; Navet, R. et al

in FEBS Letters (2002), 532

In this study we show that mitochondria of Dictyostelium discoideum contain both alternative oxidase (AOX) and uncoupling protein (UCP). AOX was stimulated by purine mononucleoside and was monomeric. UCP ... [more ▼]

In this study we show that mitochondria of Dictyostelium discoideum contain both alternative oxidase (AOX) and uncoupling protein (UCP). AOX was stimulated by purine mononucleoside and was monomeric. UCP was stimulated by free fatty acids and was poorly sensitive to GTP. Both proteins collaborated in energy dissipation when activated together. AOX expression in free-living ameboid cells decreased strongly from exponential to stationary phase of growth but much less during starvation-induced aggregation. In contrast, UCP expression was constant in all conditions indicating permanent need. Our results suggest that AOX could play a role in cell differentiation, mainly by protecting prespore cells from programmed cell death. [less ▲]

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See detailUse of multisite quantitative ultrasonography for noninvasive assessment of bone in horses
Carstanjen, B.; Lepage, O. M.; Detilleux, Johann ULg et al

in American Journal of Veterinary Research (2002), 63(10), 1464-1469

OBJECTIVE: To evaluate the usefulness of multisite quantitative ultrasonography for noninvasive assessment of bone in horses. SAMPLE POPULATION: 12 healthy horses and both forelimbs from 8 clinically ... [more ▼]

OBJECTIVE: To evaluate the usefulness of multisite quantitative ultrasonography for noninvasive assessment of bone in horses. SAMPLE POPULATION: 12 healthy horses and both forelimbs from 8 clinically normal horses. PROCEDURE: For in vivo measurements, various regions of interest (ROI) were examined on the third metacarpal bone, radius, and tibia. Precision error for speed of sound (SOS) measurements was obtained by measuring each ROI of 4 horses 10 times with probe repositioning. Additionally, 3 operators measured each aspect of the third metacarpal bone of 6 horses 5 times each. For ex vivo measurements, third metacarpal bones were examined at 9 ROI, and SOS measurements were performed before and after soft tissue removal. One ROI of a single forelimb was subjected to 96 ex vivo measurements with 3 different contact media. RESULTS: The lateral aspect of the third metacarpal bone had significantly higher SOS values than the dorsal and medial aspect of the third metacarpal bone. No difference was obtained between SOS values of the lateral and medial aspect of the radius. The tibia had significantly higher SOS values than the lateral aspect of the radius and the dorsal and medial aspect of the third metacarpal bone. Intraoperator coefficients of variation ranged from 0.62 to 3.15%, and interoperator coefficients of variation ranged from 0.78 to 2.70%. Values of SOS were highest when silicone oil was used as the contact medium. CONCLUSIONS AND CLINICAL RELEVANCE: Speed of sound measurements obtained by quantitative ultrasonography in axial transmission mode can be used to precisely measure superficial cortical bone properties of third metacarpal bone, radius, and tibia in horses. [less ▲]

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See detailQuels espoirs de remyélinisation dans la sclérose en plaques ?
Rogister, Bernard ULg; Wislet, Sabine ULg; Belachew, Shibeshih ULg

in Agenda Psychiatrie (L') (2002), 24

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See detailEcological network and local authorities - sociological instrument
Mougenot, Catherine ULg; Roussel, Laurence

in Nature and environment (2002), (126), 37

Ever closer links have been forged between caring for nature on the one hand and human activities on the other. In recent years there has been a shift from an interest in reserve-based nature, which ... [more ▼]

Ever closer links have been forged between caring for nature on the one hand and human activities on the other. In recent years there has been a shift from an interest in reserve-based nature, which excluded man and human activities, to an increasingly powerful nature-culture relationship. Nature protection became nature conservation and then nature development with the integration of socio-economic and cultural aspects. Within the framework of the setting-up of the pan-european ecological network, these sociological aspects have a great importance for establishing an ecological network where the scientific aspects of biodiversity protection must co-exist with nature management and development. [less ▲]

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See detailCytotoxic aporphine alkaloids from Cassytha filiformis.
Stevigny, C.; Block, S.; De Pauw-Gillet, Marie-Claire ULg et al

in Planta Medica (2002), 68(11), 1042-4

Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine ... [more ▼]

Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytotoxic activities on cancer and non-cancer cell lines in vitro. Neolitsine was the most active against HeLa and 3T3 cells (IC 50 :21.6 microM, and 21.4 microM, respectively). Cassythine and actinodaphnine showed the highest activity against Mel-5 (IC 50 : 24.3 microM and 25.7 microM, respectively) and HL-60 (IC 50 : 19.9 microM and 15.4 microM, respectively). This is the first report on the cytotoxic activity of C. filiformis extract and of neolitsine and cassythine. Furthermore, the complete NMR data of cassythine and actinodaphnine are given here for the first time. [less ▲]

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See detailEffects of repetitive transcranial magnetic stimulation on visual evoked potentials in migraine.
Bohotin, V.; Fumal, Arnaud ULg; Vandenheede, M. et al

in Brain : A Journal of Neurology (2002), 125(Pt 4), 912-22

Between attacks, migraine patients are characterized by potentiation instead of habituation of stimulation-evoked cortical responses. It is debated whether this is due to increased or decreased cortical ... [more ▼]

Between attacks, migraine patients are characterized by potentiation instead of habituation of stimulation-evoked cortical responses. It is debated whether this is due to increased or decreased cortical excitability. We have studied the changes in visual cortex excitability by recording pattern-reversal visual evoked potentials (PR-VEP) after low- and high-frequency repetitive transcranial magnetic stimulation (rTMS), known respectively for their inhibitory and excitatory effect on the cortex. In 30 patients (20 migraine without, 10 with aura) and 24 healthy volunteers, rTMS of the occipital cortex was performed with a focal figure-of-eight magnetic coil (Magstim). Nine hundred pulses were delivered randomly at 1 or 10 Hz in two separate sessions. Stimulus intensity was set to the phosphene threshold or to 110% of the motor threshold if no phosphenes were elicited. Before and after rTMS, PR-VEP were averaged sequentially in six blocks of 100zztieresponses during uninterrupted 3.1 Hz stimulation. In healthy volunteers, PR-VEP amplitude was significantly decreased in the first block after 1 Hz rTMS and the habituation normally found in successive blocks after sustained stimulation was significantly attenuated. In migraine patients, 10 Hz rTMS was followed by a significant increase of first block PR-VEP amplitude and by a reversal to normal habituation of the potentiation (or dishabituation) characteristic of the disorder. This effect was similar in both forms of migraine and lasted for at least 9 min. There were no significant changes of PR-VEP amplitudes after 1 Hz rTMS in migraineurs and after 10 Hz rTMS in healthy volunteers, nor after sham stimulation. The recovery of a normal PR-VEP habituation pattern after high-frequency rTMS is probably due to activation of the visual cortex and the dishabituation in healthy volunteers to cortical inhibition. We conclude, therefore, that the deficient interictal PR-VEP habituation in migraine is due to a reduced, and not to an increased, pre-activation excitability level of the visual cortex. [less ▲]

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See detailContinuité de la délinquance entre l’adolescence et l’âge adulte
Born, Michel ULg

in Criminologie (2002), 35(1), 53-67

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See detailCompte-rendu de l'ouvrage de D. Cardon : La Draperie au Moyen Age. Essor d'une grande industrie européenne
Xhayet, Geneviève ULg

in Revue d'Histoire des Sciences (2002), 55(4), 560-561

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See detailRespiratory feedback in the generation of emotion
Philippot, P; Chapelle, G; Blairy, Sylvie ULg

in Cognition & Emotion (2002), 15(5), 605-627

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See detailLa réforme de l'adoption pas à pas. Note sous C.A., 28 novembre 2001
Leleu, Yves-Henri ULg

in Journal des Tribunaux (2002)

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See detailModelled glacial and non-glacial HCO3-, Si and Ge fluxes since the LGM: little potential for impact on atmospheric CO2 concentrations and a potential proxy of continental chemical erosion, the marine Ge/Si ratio
Jones, Ian W; Munhoven, Guy ULg; Tranter, Martyn et al

in Global and Planetary Change (2002), 33(1-2), 139-153

The runoff and riverine fluxes of HCO3-, Si and Ge that arise from chemical erosion in non-glaciated terrain, are modelled at six time steps from the Last Glacial Maximum (LGM) to the present day. The ... [more ▼]

The runoff and riverine fluxes of HCO3-, Si and Ge that arise from chemical erosion in non-glaciated terrain, are modelled at six time steps from the Last Glacial Maximum (LGM) to the present day. The fluxes that arise from the Great Ice Sheets are also modelled. Terrestrial HCO3- fluxes decrease during deglaciation, largely because of the reduction in the area of the continental shelves as sea level rises. The HCO3- fluxes. and the inferred consumption of atmospheric CO2 are used as inputs to a carbon cycle model that estimates their impact on atmospheric CO2 concentrations ((CO2)-C-atms). A maximum perturbation of (CO2)-C-atms by similar to 5.5 ppm is calculated, The impact of solutes from glaciated terrain is small in comparison to those from non-glaciated terrain. Little variation in terrestrial Si and Ge fluxes is calculated (< 10%). However, the global average riverine Ge/Si ratio may be significantly perturbed if the glacial Ge/Si ratio is high. At present. variations in terrestrial chemical erosion appear to have only a reduced impact on (CO2)-C-atms and only little influence on the global Si and Ge cycle and marine Ge/Si ratios during deglaciation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailApplication of the laser beam deflection to the study of temperature filed and heat transfer in natural convection,
Cerisier, P.; Sylvain, J. D.; Dauby, Pierre ULg

in Experiments in Fluids (2002), 33

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See detailAbsolute and relative contraindications to liver transplantation. A perpetually moving frontier.
Detry, Olivier ULg; De Roover, Arnaud ULg; Delwaide, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2002), 65(2), 133-4

In this paper the authors discussed the absolute and relative contraindications to liver transplantation. These contraindications are not fixed, and may change with medical progress and experience ... [more ▼]

In this paper the authors discussed the absolute and relative contraindications to liver transplantation. These contraindications are not fixed, and may change with medical progress and experience. Certainly, the recent advent of adult-to-adult living related liver transplantation may somehow change the management of patients with relative contra-indications to cadaveric liver transplantation, as they may be potential candidates for living related liver transplantation. [less ▲]

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See detailRegelgeving inzake het zelfbeschikkingsrecht, Redactie Privaat
Leleu, Yves-Henri ULg

in Tijdschrift voor Privaatrecht (2002)

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See detailEthno-Ecological approach of Tibet south-central rural environment knowledge as a support to Kashin-Beck disease's etiology
Malaisse, François ULg; Begaux, Françoise; Chasseur, Camille et al

in Bulletin des Séances de l'Académie Royale des Sciences d'Outre-Mer (2002), 48

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See detailApproche diagnostique de la dissection carotidienne. A propos de deux cas.
Deflandre, E.; Tshibanda, L.; NCHIMI LONGANG, Alain ULg et al

in Revue Médicale de Liège (2002), 57(2), 85-90

Two cases of acute internal carotid dissection are presented. Typical symptoms, pathogeny and imaging features are reviewed. Magnetic Resonance is actually the best technique for the diagnosis of internal ... [more ▼]

Two cases of acute internal carotid dissection are presented. Typical symptoms, pathogeny and imaging features are reviewed. Magnetic Resonance is actually the best technique for the diagnosis of internal carotid artery dissection, which should be searched in young patients presenting neurologic and cervico-facial symptoms. [less ▲]

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See detailEtude par spectroscopie de génération de la fréquence somme de l'interface méthanol-platine
Vidal, F.; Busson, B.; Six, C. et al

in J. Phys. IV France (2002), 12

La spectroscopie vibrationnelle non-linéaire par génération de la fréquence somme est une sonde particulièrement adaptée à l'étude des interfaces entre milieux denses. Cette technique a été appliquée à l ... [more ▼]

La spectroscopie vibrationnelle non-linéaire par génération de la fréquence somme est une sonde particulièrement adaptée à l'étude des interfaces entre milieux denses. Cette technique a été appliquée à l'étude de l'interface électrochimique monocristal de platine/solution acide de méthanol, système qui constitue un modèle de pile à combustible, dispositif où l'énergie chimique est directement convertie en énergie électrique. Les propriétés vibrationnelles dépendent fortement de l'orientation cristallographique de l'électrode de platine. [less ▲]

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See detailNew antiobesity agents in type 2 diabetes: overview of clinical trials with sibutramine and orlistat.
Scheen, André ULg; Ernest, Philippe ULg

in Diabètes & Métabolism (2002), 28(6 Pt 1), 437-45

Besides genetic predisposition, obesity is the most important risk factor for the development of type 2 diabetes mellitus. Even modest weight reduction can improve blood glucose control in overweight ... [more ▼]

Besides genetic predisposition, obesity is the most important risk factor for the development of type 2 diabetes mellitus. Even modest weight reduction can improve blood glucose control in overweight subjects. After failure of lifestyle modifications, antiobesity drugs such as orlistat, a potent and selective inhibitor of gastric and pancreatic lipases that reduces lipid intestinal absorption, or sibutramine, a noradrenaline and 5-hydroxytryptamine reuptake inhibitor that regulates food intake, may be considered to favour weight loss and/or weight maintenance. Several placebo-controlled studies have recently demonstrated that both drugs are able to promote weight loss in obese type 2 diabetic patients treated with diet alone, sulphonylureas, metformin or insulin. The greater weight reduction as compared to placebo was associated with a significant reduction of glycated haemoglobin levels and/or of the doses of classical antihyperglycaemic agents, especially in good responders who lost at least 10% of initial body weight. In addition, vascular risk factors associated to insulin resistance were also reduced after weight loss. These antiobesity agents may also contribute to delay or prevent the progression from impaired glucose tolerance to overt type 2 diabetes in at risk obese individuals ("Xenical in the prevention of diabetes in obese subjects" trial). Large long-term prospective studies, such as the "Sibutramine cardiovascular and diabetes outcome study" should better determine the place of pharmacological anti-obesity strategy in the overall management of obese patients with impaired glucose tolerance or type 2 diabetes. [less ▲]

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See detailSensitive and high throughput metabolite assays for inorganic pyrophosphate, ADPGlc, nucleotide phosphates, and glycolytic intermediates based on a novel enzymic cycling system.
Gibon, Yves; Vigeolas, Hélène ULg; Tiessen, Axel et al

in Plant Journal (The) (2002), 30(2), 221-35

Metabolite assays are required to characterise how metabolism changes between genotypes during development and in response to environmental perturbations. They provide a springboard to identify important ... [more ▼]

Metabolite assays are required to characterise how metabolism changes between genotypes during development and in response to environmental perturbations. They provide a springboard to identify important regulatory sites and investigate the underlying mechanisms. Due to their small size, Arabidopsis seeds pose a technical challenge for such measurements. A set of assays based on a novel enzymic cycling system between glycerol-3-phosphate dehydrogenase and glycerol-3-phosphate oxidase have been developed and optimised for use with growing Arabidopsis seeds. In combination with existing assays they provide a suite of high throughput, sensitive assays for the immediate precursors for starch (adenine diphosphate glucose) and lipid (acetyl coenzyme A, glycerol-3-phosphate) synthesis, as well as pyrophosphate, ATP, ADP and most of the glycolytic intermediates. A method is also presented to rapidly quench intact siliques, lyophilise them and then manually separate seeds for metabolite analysis. These techniques are used to investigate changes in overall seed metabolite levels during development and maturation, and in response to a stepwise decrease of the external oxygen concentration. [less ▲]

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See detailBelgian-style Human Resource Management: A Case of Mistaken Identity
Claus, Lisbeth; Vloeberghs, Daniel; Pichault, François ULg

in European Management Journal (2002), 20(4), 438-446

Discusses various forces that affect the future of human resource management (HRM) in Belgium. Development of HRM in the country; Specific forces that have shaped the development and character of HRM ... [more ▼]

Discusses various forces that affect the future of human resource management (HRM) in Belgium. Development of HRM in the country; Specific forces that have shaped the development and character of HRM; Details of the condition of HRM in the country. [less ▲]

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See detailA simple approach for the design of steel and composite sway building frames
Maquoi, René ULg; Jaspart, Jean-Pierre ULg

in Steel Structures (2002), 2(n°1), 1-11

The Merchant-Rankine approach is a practical design procedure which allows to predict the ultimate resistance of sway steel building frames with rigid structural joints. In the present paper the ... [more ▼]

The Merchant-Rankine approach is a practical design procedure which allows to predict the ultimate resistance of sway steel building frames with rigid structural joints. In the present paper the background and the traditional field of application of the Merchant-Rankine formula are first described. Its extension to the design of steel frames with so-called semi-rigid joints is then presented and justified. Finally its application to steel-concrete sway composite building frames is investigated and first conclusions of this work are drawn. [less ▲]

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See detailPreemptive cellular immunotherapy after T-cell-depleted allogeneic hematopoietic stem cell transplantation.
Baron, Frédéric ULg; Beguin, Yves ULg

in Biology of Blood & Marrow Transplantation (2002), 8(7), 351-9

GVHD is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). GVHD is due to donor lymphocytes that are cotransplanted with donor stem cells. These donor ... [more ▼]

GVHD is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (HSCT). GVHD is due to donor lymphocytes that are cotransplanted with donor stem cells. These donor lymphocytes are primed by histocompatibility differences between donors and recipients and activated by a cytokine storm caused by the conditioning regimen. The most efficient method for prevention of GVHD consists of T-cell depletion (TCD) of the graft. However, TCD usually leads to an increased risk of leukemia relapse because of the loss of the graft-versus-leukemia (GVL) effect. Several groups have studied the feasibility of preemptive donor lymphocyte infusion (DLI) to lessen the impact of TCD on leukemia relapse. Preemptive DLI is given several weeks to months after the transplantation, ie, after the cytokine storm and after the patient has recovered from conditioning-regimen-related toxicities. After briefly discussing various techniques of TCD of the graft and the efficacy of DLI, this article reviews the first clinical studies evaluating a strategy of TCD of the graft followed by preemptive DLI. [less ▲]

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See detailL'allergie aux aromes et parfums: anathème sur un attrait épicurien?
Goffin, Véronique ULg; Nikkels, Arjen ULg; Cornil, F. et al

in Revue Médicale de Liège (2002), 57(9), 605-9

Aromas and fragrances are present in many cosmetics, some topical drugs, food and various hygiene, household and industrial products. They can be responsible for contact dermatitis. Multiple ... [more ▼]

Aromas and fragrances are present in many cosmetics, some topical drugs, food and various hygiene, household and industrial products. They can be responsible for contact dermatitis. Multiple sensitizations can even involve in various combinations some fragrance compounds, a given degradation product or a contaminant. The diagnosis relies on clinical examination and oriented anamnesis. A histological examination is sometimes necessary. Specific path testing brings insight on the culprit chemical compounds. [less ▲]

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See detailThe use of placebo-controlled and non-inferiority trials for the evaluation of new drugs in the treatment of postmenopausal osteoporosis
Delmas, P. D.; Calvo, Gisèle ULg; Boers, M. et al

in Osteoporosis International (2002), 13(1), 1-5

Registration of new agents for the treatment of postmenopausal osteoporosis has been based over the past few years on placebo-controlled phase III trials with the incidence of patients with new vertebral ... [more ▼]

Registration of new agents for the treatment of postmenopausal osteoporosis has been based over the past few years on placebo-controlled phase III trials with the incidence of patients with new vertebral/nonvertebral fractures as the most usual primary endpoint. The use of a placebo in diseases where an active treatment is available has been a matter of debate following the update of the Declaration of Helsinki by the World Medical Association which questioned this trial design. Current regulatory recommendations within the European Union suggest that placebo-controlled trials are still the best option when assessing the efficacy and safety of new drugs intended for the treatment of postmenopausal osteoporosis. This suggestion seems to be in apparent contradiction with the current content of the Declaration of Helsinki. This paper addresses the ethics and feasibility of placebo-controlled trials in the treatment of postmenopausal osteoporosis, in the light of available therapeutic options, and discusses possible alternative approaches in those patients where placebo treatment could be deemed to be unethical. It is concluded that placebo-controlled trials remain the most efficient design to establish the efficacy and safety of a new agent for the treatment of postmenopausal osteoporosis. Such trials are feasible and ethically acceptable in patients with osteoporosis but without prevalent vertebral fractures. Conversely, in patients with prevalent vertebral fractures, placebo-controlled trials are ethically questionable and non-inferiority trials are more appropriate. A relative margin of non inferiority of 20-30% is suggested, to be discussed on a case by case basis. [less ▲]

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See detailComprendre et prévenir la violence à l'école : vers un référentiel critique des mesures actuelles de prévention et de lutte contre la violence scolaire
Munten, Jacqueline; Jardon, Dorothée; Mouvet, Bernadette ULg

in Point sur la Recherche en Education (Le) (2002), 22

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See detailEuro- en zijn concurrenten
Meesters, Gert ULg

in Leuvense Bijdragen (2002), 91(1-2), 79-96

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the ... [more ▼]

This article deals with the Dutch bound morpheme euro-, meaning ‘European’ or ‘Europe’ in relatively young word formations. The morpheme in question is not to be confounded with the word euro for the European currency. The article especially deals with the relationship between word formation with euro- and three other means of expressing more or less the same meaning: word formation with EG- (abbreviation of Europese Gemeenschap, i.e. European Union) as a first component, word formation with Europa- (Europe) as a first component and word groups with the adjective Europees (European). This relationship is explored in two comparative studies. First the token frequency in a corpus is investigated. It turns out that euro- is more frequent than Europa-, but less frequent than EG- and Europees. In a second comparison the semantic-functional domains of the four alternatives are considered in detail. Euro- apparently can be used as an alternative for Europees and EG- when the referents are related to the European Union, and as an alternative for Europees in ‘bilateral’ adjectives such als Euro-Russisch. It also has a few domains of its own: commercial proper names and words expressing an attitude towards the European Union. An additional analysis of individual words and word groups with different alternatives from this paradigm as a first component but the same second component reveals that even in individual cases of competition with other alternatives, the variant with euro- is sometimes the most frequent or the institutionalized form. It is concluded that within the linguistic potential of naming referents that relate to Europe, euro- has its own specific value as a productive means of word formation. [less ▲]

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See detailOral antivirals revisited in the treatment of herpes zoster: what do they accomplish?
Nikkels, Arjen ULg; Pierard, Gérald ULg

in American Journal of Clinical Dermatology (2002), 3(9), 591-8

Oral antiviral agents currently represent the most important therapeutic keystone in the treatment of herpes zoster. Three oral antiviral agents are available for the treatment of herpes zoster: acyclovir ... [more ▼]

Oral antiviral agents currently represent the most important therapeutic keystone in the treatment of herpes zoster. Three oral antiviral agents are available for the treatment of herpes zoster: acyclovir, its derivative valacyclovir, and famciclovir. Meta-analysis of published data has shown that oral acyclovir significantly reduces various herpes zoster-related symptoms as well as the duration, intensity and prevalence of zoster-associated pain (ZAP). However, this drug does not influence postherpetic neuralgia. The newer agents famciclovir and valacyclovir exhibit a better oral bioavailability than acyclovir. These agents have demonstrated similar efficacy to acyclovir with ZAP and they require less frequent administration. When initiated within 72 hours, oral antiviral therapy of herpes zoster is beneficial in selected, elderly immunocompetent patients, reducing the duration and intensity of ZAP and providing more rapid skin lesion healing. Oral antivirals are also of benefit in immunocompromised patients with uncomplicated herpes zoster. However, signs of cutaneous and visceral dissemination should be monitored; if signs occur, intravenous antiviral therapy is indicated. [less ▲]

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See detailMagnetic properties of Ga-doped lanthanum manganite with controlled oxygen stoichometry
Vertruyen, Bénédicte ULg; Hebert, Sylvie; Maignan, Antoine et al

in Crystal Engineering (2002), 5

Stoichiometric LaMnO3 is an insulator whose A-type antiferromagnetic structure at low temperature is mainly connected to the Jahn-Teller distortion of the MnO6 octahedra. The substitution of non magnetic ... [more ▼]

Stoichiometric LaMnO3 is an insulator whose A-type antiferromagnetic structure at low temperature is mainly connected to the Jahn-Teller distortion of the MnO6 octahedra. The substitution of non magnetic d(10) Ga3+ ions on the manganese site disrupts the orbital and spin orderings of the manganese ions and has a strong influence on the physical properties. The antiferromagnetic order is progressively destroyed while the ferromagnetic component increases. At the same time, the distortion of the orthorhombic cell decreases and the high temperature structural Jahn-Teller transition disappears. Such studies on manganese site substitutions give insight into the physics of the Mn-O three-dimensional network, which is supposed to be the key feature in the CMR manganites. (C) 2003 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailSplit face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel.
Uhoda, Isabelle; Faska, Najat; Robert, Caroline et al

in Skin Research & Technology (2002), 8(3), 164-7

BACKGROUND/AIMS: Beyond subjective assessments, the effect of skin tensors is difficult to assess. The present 2-phase randomized double-blind split face study was designed to compare the effect of a gel ... [more ▼]

BACKGROUND/AIMS: Beyond subjective assessments, the effect of skin tensors is difficult to assess. The present 2-phase randomized double-blind split face study was designed to compare the effect of a gel containing 3% 2-dimethylaminoethanol (deanol, DMAE) with the same formulation without DMAE. METHODS: In a first pilot study, sensorial assessments and measures of the skin distension under suction were performed in eight volunteers. In a second study conducted in 30 volunteers, shear wave propagation was measured. RESULTS: Large interindividual variations precluded any significant finding in the first study. The DMAE formulation showed, however, a significant effect characterized by increased shear wave velocity in the direction where the mechanical anisotropy of skin showed looseness. CONCLUSION: The DMAE formulation under investigation increased skin firmness. [less ▲]

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See detailLandscape ecology – A top-down approach (J. Sanderson, L.D. Harris)
Bogaert, Jan ULg

in Acta Biotheoretica (2002), 50(2), 129-131

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See detailTraces expérimentales d’emmanchement. Identification et caractéristiques
Rots, Veerle ULg; Pirnay, Louis; Pirson, Philippe et al

in Bulletin de la Société Royale Belge d'Etudes Géologiques et Archéologiques "Les Chercheurs de Wallonie" (2002), 41

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See detailBlade-Tip Timing Measurement Of Synchronous Vibrations Of Rotating Bladed
Dimitriadis, Grigorios ULg; Carrington, Ian B.; Wright, Jan Robert et al

in Mechanical Systems & Signal Processing (2002), 16(4), 599-622

Blade-tip timing (BTT) is a promising method for the detection, measurement and analysis of blade vibrations in rotating bladed assemblies. However, the intricacies of the method when applied to real ... [more ▼]

Blade-tip timing (BTT) is a promising method for the detection, measurement and analysis of blade vibrations in rotating bladed assemblies. However, the intricacies of the method when applied to real rotating structures undergoing synchronous (Engine Ordered) vibrations are not yet fully understood. In this paper, a mathematical model is developed to simulate data from typical BTT tests of rotating assemblies. The simulator is then used in order to provide a qualitative analysis of several phenomena that can be associated with the synchronous vibrations of rotating assemblies, including mistuning, coupling, excitation at multiple Engine Orders and simultaneous synchronous and asynchronous responses. It is concluded that none of these phenomena on its own will render the identification of the frequency and amplitude of blade vibrations impossible. However, there is no single BTT data analysis method that is able to deal with all of these phenomena. [less ▲]

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See detailNew in situ generated ruthenium catalysts bearing N-heterocyclic carbene ligands for the ring-opening metathesis polymerization of cyclooctene
Delaude, Lionel ULg; Szypa, Magdalena; Demonceau, Albert ULg et al

in Advanced Synthesis & Catalysis (2002), 344(6-7), 749-756

New 1,3-diarylimidazol(in)ium chlorides bearing phenyl, 1-naphthyl, 4-biphenyl, 2-tolyl, 2,6-dimethylphenyl, and 3,5-dimethylphenyl substituents were synthesized. They were combined with [RuCl2 (p-cymene ... [more ▼]

New 1,3-diarylimidazol(in)ium chlorides bearing phenyl, 1-naphthyl, 4-biphenyl, 2-tolyl, 2,6-dimethylphenyl, and 3,5-dimethylphenyl substituents were synthesized. They were combined with [RuCl2 (p-cymene)](2) and potassium tert-butoxide or sodium hydride to generate the corresponding ruthenium-N-heterocyclic carbene complexes in situ. Catalyst precursors derived from imidazol(in)ium salts bearing the 2,4,6-trimethylphenyl (mesityl) and the 2,6-diisopropylphenyl groups were also prepared. The catalytic activity of all these species in the photoinduced ring-opening metathesis polymerization of cyclooctene was investigated. The C4-C5 double bond in the imidazole ring of the N-heterocyclic carbene ligands was not crucial to achieve high catalytic efficiencies. The presence or the absence of alkyl groups on the ortho positions of the phenyl rings had a more pronounced influence. Blocking all the ortho positions was a requisite for obtaining efficient catalysts. Failure to do so probably results in the ortho-metallation of the carbene ligand, thereby altering the coordination sphere of the ruthenium active centers. [less ▲]

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See detailLes antagonistes calciques ont-ils une place de première ligne dans le traitement de l'hypertension artérielle?
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2002), 57(2), 79-84

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one ... [more ▼]

During the nineties, a controversy was noted in the literature about the potential risk of using calcium antagonists in the treatment of hypertension. Several recent studies, such as the INSIGHT’s one have not confirmed this provided that one uses long-acting molecule. But the real beneficial effect due to the different antihypertensive classes is mainly linked to the magnitude of the blood pressure lowering effect. [less ▲]

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See detailEstimating effects of permanent environment, lactation stage, age, and pregnancy on test-day yield.
Bormann, J.; Wiggans, G. R.; Philpot, J. C. et al

in Journal of Dairy Science (2002), 85(1), 2631-26321

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See detailContinuity preserving modified maximum cross-correlation technique
Zavialov, Peter O.; Grigorieva, Julia V.; Moller, Osmar O. et al

in Journal of Geophysical Research. Oceans (2002), 107(C10, SEP-OCT),

The maximum cross-correlation (MCC) method reconstructs the surface advective velocity fields from the displacements of spatial patterns in pairs of sequential satellite (normally infrared) images ... [more ▼]

The maximum cross-correlation (MCC) method reconstructs the surface advective velocity fields from the displacements of spatial patterns in pairs of sequential satellite (normally infrared) images. However, the performance of the conventional MCC method is not always satisfactory. One of the main reasons for this is the fact that the method can correctly estimate only the velocity component parallel to the gradient of the property depicted in the images, while any small displacement perpendicular to the gradient (i.e., directed along the isolines) essentially maps the spatial pattern onto itself and therefore can not be detected using the conventional MCC technique. In the present work we propose a modification of the MCC method that allows circumventing this basic deficiency and improving the performance of the MCC technique. In this approach, the "cross-isoline'' components of the velocity field are obtained as in the conventional MCC scheme; however, the "along-isoline'' components derived from the MCC are disregarded as unreliable. Instead, the "true'' along-isoline components are then reconstructed from the given cross-isoline velocity field based on the continuity requirement and on the condition of no normal flow at solid boundaries. This inverse problem is solved by constructing the two-dimensional stream function in the curvilinear coordinate frame associated with the image isolines. The method is illustrated using AVHRR images from the southwestern Atlantic Ocean and the Black Sea. The results are compared with some direct drifter and current meter measurements and geostrophic estimates. [less ▲]

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See detailRéplication, clivage-encapsidation et recombinaison de l'ADN des herpèsvirus
Schynts, Frédéric; Meurens, François; Muylkens, Benoît ULg et al

in Virologie (2002), 6

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See detailNudging acne by topical beta-lipohydroxy acid (LHA), a new comedolytic agent.
Pierard, Gérald ULg; Rougier, A.

in European Journal of Dermatology (2002), 12(4), -

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