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See detailThe effect of food on growth and metamorphosis of paedomorphs in Triturus alpestris apuanus
Denoël, Mathieu ULg; Poncin, Pascal ULg

in Archiv für Hydrobiologie (2001), 152(4), 661-670

The effect of food level on growth and metamorphosis of paedomorphs was examined in an experimental replicated design in Triturus alpestris apuanus. Paedomorphosis concerns the retention of larval ... [more ▼]

The effect of food level on growth and metamorphosis of paedomorphs was examined in an experimental replicated design in Triturus alpestris apuanus. Paedomorphosis concerns the retention of larval characteristics in adult individuals. Newts that forgo metamorphosis and then retain gill and gill slits in the adult stage maintain an aquatic life but keep potential for undergoing metamorphosis. Paedomorphs metamorphosed later in treatments with food as a non-limiting factor than in stressful treatments where food was limited. Timing of metamorphosis did not differ between males and females. Food level greatly affected growth rates. These results confirm and extend optimality models that predict paedomorphosis under advantageous aquatic conditions (paedomorph advantage hypothesis) and metamorphosis in stressful aquatic habitats. [less ▲]

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See detailL'expertise pénale en matière de responsabilité médicale
Boxho, Philippe ULg

in Consilio manuque (2001), 28

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See detailTreatment of drug-induced toxic epidermal necrolysis (Lyell’s syndrome) with intravenous human immunoglobulins
Paquet, Philippe ULg; Jacob, Emilie ULg; Damas, Pierre ULg et al

in Burns : Journal of the International Society for Burn Injuries (2001), 27(6), 652-655

Toxic epidermal necrolysis (TEN) is a rare drug-induced life-threatening disease. Currently, the disease is only treated by supportive and antiseptic measures. Quite recently intravenous immunoglobulins ... [more ▼]

Toxic epidermal necrolysis (TEN) is a rare drug-induced life-threatening disease. Currently, the disease is only treated by supportive and antiseptic measures. Quite recently intravenous immunoglobulins (IG) were shown to be a promising TEN treatment. The rationale for their use is based on the fact that keratinocyte apoptosis in TEN involves the CD95 (APO-1/Fas) cell surface receptor–ligand system. We successfully treated a TEN patient with high dose of intravenous IG. The clinical recovery appeared exceptionally rapid. Immunohistochemistry showed that the IG action probably developed on the CD95 receptor–ligand system at the keratinocytes surface. [less ▲]

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See detailResponsabilité pénale et faute pénale
Boxho, Philippe ULg

in Revue Médicale de Liège (2001), 56

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See detailAutour d'Henri Bles à Liège
Allart, Dominique ULg; Fraiture Pascale; Oger, Cécile ULg et al

in Feuillets de la Cathédrale de Liège (2001), 46-53

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See detailUnraveling Oligodendrocyte Origin and Function by Cell-Specific Transgenesis
Belachew, Shibeshih ULg; Yuan, Xiaoqing; Gallo, Vittorio

in Developmental Neuroscience (2001), 23(4-5), 287-98

Besides the role of mature oligodendrocytes in myelin synthesis during the development of the central nervous system (CNS), the oligodendrocyte lineage also encompasses the largest pool of postnatal ... [more ▼]

Besides the role of mature oligodendrocytes in myelin synthesis during the development of the central nervous system (CNS), the oligodendrocyte lineage also encompasses the largest pool of postnatal proliferating progenitors whose behavior in vivo remains broadly elusive in health and disease. We describe here transgenic models that allow us to track the functions and origins of such cells by using proteolipid protein and 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) gene promoters to direct oligodendroglial expression of different reporters, in particular the green fluorescent protein (GFP). We emphasize that the CNP-GFP mouse, which targets the entire oligodendroglial lineage from embryonic life to adulthood, provides an outstanding tool to study the in vivo properties of oligodendrocyte progenitor cells in normal and damaged CNS. [less ▲]

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See detailElement removal in harvested tree biomass: scenarios for critical loads in Wallonia, south Belgium
Bosman, Bernard ULg; Remacle, Jean; Carnol, Monique ULg

in Water, Air & Soil Pollution : Focus (2001), 1

The critical load concept is now widely used as a tool for developing emission control policies in Europe. As a signatory country of the Convention of Long-Range Transboundary Air Pollution, critical ... [more ▼]

The critical load concept is now widely used as a tool for developing emission control policies in Europe. As a signatory country of the Convention of Long-Range Transboundary Air Pollution, critical loads for acidity, nutrient nitrogen, nitrogen and sulphur have been calculated for the Flemish and Walloon regions in Belgium. This paper describes the methodology used for estimating critical loads for forest soils in the Walloon region according to the Steady-State Mass Balance equations. As an example the methodology was applied to the catchment `Waroneu', situated in a sensitive area of the Haute Ardenne. Main input parameters to the equations were derived from precipitation and runoff data of the catchment study. Improved estimates of nitrogen uptake (Nu) and base cation uptake (BCu) were obtained by intensive sampling of Picea abies and Quercus robur trees. Nutrient contents (Ca, Mg, K, N) and nutrient to nitrogen ratios of Picea abies reflected the poor soil quality at a site with high N deposition. Quercus robur nutrient contents increased from stem to higher order branches with a high proportion of nutrients located in the bark. However the simulation of stem only harvesting had a minor effect on critical loads. Measured wood densities were lower than reported literature values with a main effect on Nu and BCu estimates. The use of recommended default values and/or data derived from the experimental site resulted in a wide range of critical loads, some of which were largely overestimated. Results demonstrated the importance of site specific data for critical load calculations. [less ▲]

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See detailA New Design of Equilibrator to Monitor Carbon Dioxide in Highly Dynamic and Turbid Environments
Frankignoulle, M.; Borges, Alberto ULg; Biondo, Renzo ULg

in Water Research (2001), 35(5), 1344-7

A new design of equilibrator for carbon dioxide monitoring in natural waters is described. It consists in a vertical tube filled with marbles through which water is flowing while equilibrating with a ... [more ▼]

A new design of equilibrator for carbon dioxide monitoring in natural waters is described. It consists in a vertical tube filled with marbles through which water is flowing while equilibrating with a closed air circuit. It offers several advantages compared with classical equilibrators, among which is a fast response time (half-life constant approximately 30 s) and the potential to work in very turbid water. The proposed equilibrator is of particular interest to monitor carbon dioxide in coastal ecosystems, such as estuaries, which are known to be turbid and highly dynamic. Two performance tests and some field results are presented to illustrate the efficiency of the proposed system. [less ▲]

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See detailImmediate and long-term clinical and angiographic results from Wiktor stent treatment for true bifurcation narrowings.
Anzuini, A.; Briguori, C.; Rosanio, S. et al

in American Journal of Cardiology (2001), 88(11), 1246-50

From January 1996 to December 1998, 90 consecutive patients with true bifurcation lesions underwent percutaneous coronary angioplasty with Wiktor stent implantation in our centers. In 1 group (group I, n ... [more ▼]

From January 1996 to December 1998, 90 consecutive patients with true bifurcation lesions underwent percutaneous coronary angioplasty with Wiktor stent implantation in our centers. In 1 group (group I, n = 45), a simple approach (main vessel stenting and balloon angioplasty of the side branch) was pursued. In the other group (group II, n = 45), both the main vessel and the side branch were stented ("T" technique). There was no significant difference in clinical and angiographic characteristics between the 2 groups. Angiographic and procedural successes were 100% and 95.6%, respectively, in both groups. Angiographic results for the side branch were better in group II than in group I. In-hospital and long-term (12 month) major cardiac events were similar in the 2 groups. Target lesion revascularization was 15.5% in group I and 35.5% in group II (p = 0.12). In the main vessel, restenosis rate was 12.5% in group I and 25% in group II (p = 0.15). In the side branch, restenosis rate was 37.5% in group II and 12.5% in group I (p = <0.05; odds ratio 2.42; 95% confidence interval 1.05 to 6.26). Event-free probability at 12 months was 61% in group II and 80% in group I (p = 0.10). When dealing with true bifurcation lesions, a simple strategy is associated with a lower risk of restenosis in the side branch. In contrast, a complex approach does not appear to give any benefit in terms of early or long-term outcome or restenosis rate. [less ▲]

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See detailPharma-clinics. Le medicament du mois. Le celecoxib (Celebrex).
Scheen, André ULg

in Revue Médicale de Liège (2001), 56(1), 53-5

Celecoxib (Celebrex, Pharmacia) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as nonsteroidal anti-inflammatory drug (NSAID). Its current indications are ... [more ▼]

Celecoxib (Celebrex, Pharmacia) is a potent and selective inhibitor of the COX-2 isoform of cyclooxygenase which is used as nonsteroidal anti-inflammatory drug (NSAID). Its current indications are osteoarthritis and rheumatoid arthritis. The usual recommended daily dosage of celecoxib is 200 mg (in one or two intakes per day), to be increased up to 400 mg (two intakes per day) if necessary. Its clinical efficacy seems to be similar to that of other NSAIDs. However, its safety profile, especially gastro-intestinal tolerance and perhaps renal safety, is much better because of the COX-2 selectivity. [less ▲]

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See detailIntraconzole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients
Boogaerts, Marc; Maertens, Johan; van Hoof, Achiel et al

in Journal of Antimicrobial Chemotherapy (2001), 48

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See detailEl lenguaje de las personas con sindrome de Down
Rondal, Jean-Adolphe ULg; Comblain, Annick ULg

in Revista Sindrome de Down (2001), 18(68), 18-28

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See detailPrésentation
Badir, Sémir ULg; Arrivé, Michel

in Linx (2001), 44

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See detailOn the sources of work hardening in multiphase steels assisted by transformation-induced plasticity
Jacques, Pascal J.; Furnémont, Quentin; Mertens, Anne ULg et al

in Philosophical Magazine A (2001), 81(7), 1789-1812

The mechanisms effectively responsible for the enhancement of the work-hardening capabilities of multiphase steels assisted by transformation-induced plasticity are highlighted. Different microstructures ... [more ▼]

The mechanisms effectively responsible for the enhancement of the work-hardening capabilities of multiphase steels assisted by transformation-induced plasticity are highlighted. Different microstructures, some containing a proportion of retained austenite with various mechanical stabilities, are studied. The dislocation density generated within ferrite by the mechanically induced martensitic transformation of retained austenite is shown to scale with the incremental work-hardening exponent. The acoustic emission generated during tensile straining was also measured. The acoustic emission was revealed to result mainly from dislocation motion, especially from the motion of the additional dislocation density generated in intercritical ferrite by the strain-induced martensitic transformation. [less ▲]

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See detailStability of perturbed functional differential equations and stabilization of nonlinear cascades
Michiels, Wim; Sepulchre, Rodolphe ULg; Roose, Dirk

in SIAM Journal on Control & Optimization (2001), 40

In this paper the effect of bounded input perturbation on the stability of nonlinear globally asymptotically stable delay differential equations is analyzed. We investigate under which conditions global ... [more ▼]

In this paper the effect of bounded input perturbation on the stability of nonlinear globally asymptotically stable delay differential equations is analyzed. We investigate under which conditions global stability in preserved and if not, whether semi-global stabilization is possible by controlling the size or shape of the perturbation. This results in a general framework, in which the stabilization of partial linear cascade systems using partial state feedback can be treated systematically. [less ▲]

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See detailPractical Aspects Of Computational Chemistry Calculations Through Pc Networks: The Ramses-Beowulf Implementation
Beuve-Mery, D.; Rahman, M.; Ducarme, P. et al

in Journal of Computational Chemistry (2001), 22(2), 172-7

We have built clusters of PC using up to 320 processors in parallel. The first cluster was built in 1996 from 64 computers. The parallel architectures are named RAMSES. In this article, we share our ... [more ▼]

We have built clusters of PC using up to 320 processors in parallel. The first cluster was built in 1996 from 64 computers. The parallel architectures are named RAMSES. In this article, we share our experience and discuss our choices. The architecture is composed of Pentium processors connected by a 100 Mbits/s Ethernet network. Because RAMSES are built of independent computers, the system is easily maintained, and can be modified by adding or removing machines. Two programs, which are dedicated to molecular modeling and were previously developed on single machines (OSIRIS and IMPALA), have been adapted. IMPALA models peptide and protein interaction with membranes, OSIRIS simulates an ab initio folding of globular proteins. After parallelization, each program consists of two parts: one is the human/RAMSES interface, and the second is the simulation per se. The parallel architecture is transparent for the users. Tests of the IMPALA and OSIRIS efficiencies are shown and discussed. [less ▲]

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See detailRegime alimentaire du Grand-Duc du désert, Bubo ascalaphus, dans la réserve naturelle de Mergueb (M'Sila, Algérie)
Biche, Mohamed; Sellami, Medhi; Libois, Roland ULg et al

in Alauda (2001), 69(4), 554-557

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical ... [more ▼]

The diet of Bubo ascalaphus was studied in a steppe at the Mergueb nature reserve. The analysis of 141 pellets indicated that mammals were most abundant (89 %). The most frequent prey, on a numerical basis (82 %) as well as in term of biomass (96 %) was Meriones shawi trouessarti (Gerbillidae). Other preys included Jaculus orientalis (Dipodidae), and two insectivores: Crocidura russula and Hemiechinus aethiopicus. Among the avifauna, only the Spanish sparrow (Passer hispaniolensis) was a significant part of the Eagle owl dietn especially in spring. Arthropods were represented by Scarabeidae in spring and Scorpionidae in summer but they played a minor role in the food of the Eagle owl. The originality of this diet lies in the absence of Brown hare (Lepus capensis) and the presence of only one specimen of the desert hedgehog. Although its food spectrum was very narrow in this site, the Eagle owl can be regarded as opportunistic as it concentrated on the most available prey: Meriones shawi. [less ▲]

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See detailCarbon balance gradient in European forests: should we doubt 'surprising' results? A reply to Piovesan & Adams
Jarvis, P. G.; Dolman, A. J.; Schulze, E. D. et al

in Journal of Vegetation Science (2001), 12(1), 145-150

This paper responds to the Forum contribution by Piovesan & Adams (2000) who criticized the results obtained by the EUROFLUX network on carbon fluxes of several European forests. The major point of ... [more ▼]

This paper responds to the Forum contribution by Piovesan & Adams (2000) who criticized the results obtained by the EUROFLUX network on carbon fluxes of several European forests. The major point of criticism was that the data provided by EUROFLUX are inconsistent with current scientific understanding. It is argued that understanding the terrestrial global carbon cycle requires more than simply restating what was known previously, and that Piovesan & Adams have not been able to show any major conflicts between our findings and ecosystem or atmospheric-transport theories. [less ▲]

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See detailThe Secret History of Belgian Surrealism
Delville, Michel ULg

in Samizdat (2001)

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See detailLa réception de l’art japonais en Belgique
Bawin, Julie ULg

in Art&Fact (2001)

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See detailA comparison of the efficacy and tolerability of meloxicam and diclofenac in the treatment of patients with osteoarthritis of the lumbar spine.
Valat, J P; Accardo, S; REGINSTER, Jean-Yves ULg et al

in Inflammation Research (2001), 50(Suppl 1), 30-4

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with ... [more ▼]

OBJECTIVE: The aim of this study was to evaluate the efficacy and tolerability of meloxicam compared with diclofenac in patients with osteoarthritis of the lumbar spine. SUBJECTS: 229 patients with radiologically confirmed osteoarthritis of the lumbar spine. TREATMENT AND METHODS: Once-daily meloxicam 7.5 mg tablet or diclofenac 100 mg slow release tablet. Efficacy and tolerability parameters were assessed at baseline and after 3, 7 and 14 days of treatment. RESULTS: The two drugs had equal short-term efficacy, with pain on motion of lumbar spine significantly (p<0.05) decreased at Day 3. Secondary efficacy variables were also significantly improved at Days 3, 7 and 14. There were no statistically significant differences between the two drugs, although the global tolerability of meloxicam was significantly better than for diclofenac, as assessed by the investigators (p = 0.0072) and the patients (p = 0.049). CONCLUSIONS: Meloxicam and diclofenac were equivalent in relieving the acute pain associated with osteoarthritis of the lumbar spine. However, meloxicam was much better tolerated. [less ▲]

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See detailDroits de la défense et informations relatives à la situation judiciaire du prévenu figurant indûment au dossier
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2001)

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See detailUretere retrocave chez un enfant de dix ans.
Kakanou, A.; NCHIMI LONGANG, Alain ULg; Ghuysen, M. S. et al

in Annales de Chirurgie (2001), 126(2), 156-8

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral ... [more ▼]

Retrocaval ureter is an uncommon abnormality of the inferior vena cava, which is rarely detected in the child due to its non-specific symptomatology. Despite a varying state of severity, chronic ureteral obstruction generally leads to the deterioration of renal function during adulthood. Treatment depends on the symptomatology in question, and surgical management should be as conservative as possible. [less ▲]

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See detailEffects of liming on forest soil algal communities
Kostinov, I.; Carnol, Monique ULg; Dulière, J.-F. et al

in Algological Studies (2001), 102

The effects of the application of dolomite lime (5 t ha-1) on soil algal communities were investigated in sessile oak (Quercus petraea (MATT.) LIEB.) and Norway spruce (Picea abies (L.) KARST.) plots ... [more ▼]

The effects of the application of dolomite lime (5 t ha-1) on soil algal communities were investigated in sessile oak (Quercus petraea (MATT.) LIEB.) and Norway spruce (Picea abies (L.) KARST.) plots situated in the Belgian Ardenne. Chlorophyta (60 taxa) were by far the most diverse group, followed by Xanthophyceae (10 taxa), Bacillariophyceae (3 taxa), Cyanophyceae (2 taxa) and Euglenophyceae (1 taxon). In both forest types, liming lead to a significant increase in soil pH, exchangeable magnesium and calcium. In the limed Quercus plots available phosphorus and soil solution nitrate concentrations were also increased. The soil algal diversity was similar in oak and spruce control plots and in limed spruce plots. However, in the limed oak plots a significantly higher algal diversity was observed. On the basis of a CCA analysis, three clusters of plots could be distinguished: a) Picea control plots, b) limed Picea and control Quercus plots, c) limed Quercus plots. Both soil pH and nutrient availability seem to be important in determining algal species composition in these forest soils. [less ▲]

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See detail« En quête d’un nouveau droit du travail »
Florence, Eric ULg

in Revue Bibliographique de Sinologie = Review of Bibliography in Sinology (2001), Vol. XIV

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See detailMémoire à court terme et pathologies du langage
Poncelet, Martine ULg; Majerus, Steve ULg; Van der Linden, Martial ULg

in Rééducation Orthophonique (2001), 208

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See detailÉvolution des accessibilités et des mobilités des localisations commerciales
Merenne-Schoumaker, Bernadette ULg

in Travaux de l’Institut de Géographie de Reims (2001), 27(107-108), 7-23

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly ... [more ▼]

In order to be able to study the links between the evolution of accessibilities and mobilities and the dynamics of the commercial localizations, the article has been organized in three parts : firstly, the definition of the concepts of accessibility and mobility as well as the distance; secondly, analysis of the role of these two concepts in the commercial field and the their most evident recent evolutions; lastly, research into corresponding links. On the basis of this work, everything indicates the priority of mobility over accessibility as well as very close relations between the mutations of urbanized territories and the installation of the new commercial framework, which is strongly governed by car mobility. [less ▲]

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See detailMicro-analyse des mécanismes de la reprise démographique des villages de l'Ardenne du Nord-Est : le cas de Burtonville
Schmitz, Serge ULg

in Espace, Populations, Sociétés (2001)

If they are well selected, macro scale analyses permit to underline some mechanisms that remain hidden or are difficult to distinguish with micro scale analysis. The populations' stories an history of ... [more ▼]

If they are well selected, macro scale analyses permit to underline some mechanisms that remain hidden or are difficult to distinguish with micro scale analysis. The populations' stories an history of Burtonville in their regional context show : - lags of demographic revivals between villages and small towns - relevance of material constraints inherent in a small village for the demographic development - relevance of landed property and genealogy for the village evolution - links between demographic and economic evolutions - diversification of environmental aspirations and their results on migrations. [less ▲]

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See detailEvidence of rainbow trout prolactin interaction with its receptor through unstable homodimerisation.
Le Rouzic, Philippe; Sandra, Olivier; Grosclaude, Jeanne et al

in Molecular & Cellular Endocrinology (2001), 172(1-2), 105-13

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow ... [more ▼]

This study aims to characterise Prolactin receptor (PRLR) in rainbow trout for which no information is available despite the availability of Salmonid PRL preparations. By screening a freshwater rainbow trout intestine cDNA library with a probe corresponding to the extracellular domain (ECD) of tilapia PRLR, we have cloned a 2.5 kb insert coding for the PRLR. The mature protein of 614 amino acid residues is similar to PRLR isolated in tilapia and also the long form of mammalian PRLR. Analysis of PRLR gene expression in osmoregulatory organs revealed the presence of a unique transcript, thus confirming the involvement of this hormone in the control of osmoregulation in this fish species. By using surface plasmon resonance (SPR) technology, kinetic measurement of interaction between trout PRL and its receptor ECD was studied. This approach allowed us to demonstrate the formation of a transient, unstable homodimeric complex. This unstability could explain the inability to perform binding experiments using homologous PRL. In contrast, heterologous lactogenic ligands were able to interact through a more stable complex. Whether these characteristics of PRL-receptor interaction in rainbow trout are different to what occurs in tilapia where a homologous radioreceptor assay was developed would require further studies. [less ▲]

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See detailLarge-Scale Phenotypic Analysis Reveals Identical Contributions To Cell Functions Of Known And Unknown Yeast Genes
Bianchi, Mm.; Ngo, S.; Vandenbol, Micheline ULg et al

in Yeast (2001), 18(15),

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See detailBelgian normative data of the temperament and character inventory
Hansenne, Michel ULg; Le Bon, O.; Gauthier, Audrey ULg et al

in European Journal of Psychological Assessment (2001), 17(1), 56-62

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 ... [more ▼]

The Temperament and Character Inventory (TCI) is a 226-item self-questionnaire developed to assess the seven dimensions of personality described by Cloninger and his colleagues. Normative data from 322 representative French-speaking subjects from Belgium are presented and the psychometric properties are discussed. Mean scores of temperament dimensions were appreciably different from those published by Cloninger. In our sample, novelty seeking and self-transcendence scores were lower and harm avoidance scores were higher compared to US norms. The other dimensions were almost identical. The factorial analysis showed that the hypothesized factor structure of temperament and character dimensions was almost confirmed. The present study also confirmed that the TCI scales were weakly related among themselves. The relationships were consistent with those reported by previous reports. Gender differences were also found for different dimensions. [less ▲]

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See detailEndothelin in the equine hypoxic pulmonary vasoconstrictive response to acute hypoxia
Benamou, A. E.; Marlin, D. J.; Lekeux, Pierre ULg

in Equine Veterinary Journal (2001), 33(4), 345-353

Elevated concentrations of endothelin (ET), a potent endothelium-derived vasoactive peptide, have been reported in a number of pathophysiological conditions associated with pulmonary hypertension, both in ... [more ▼]

Elevated concentrations of endothelin (ET), a potent endothelium-derived vasoactive peptide, have been reported in a number of pathophysiological conditions associated with pulmonary hypertension, both in the horse and other species. We have previously shown, both in vitro and in vivo, that the pulmonary and systemic vascular response to exogenous ET is mediated predominantly via ET(A) receptors. Our hypothesis in the present study was that ET is involved in the equine hypoxic pulmonary vasoconstrictive response to acute hypoxia. In this study, we investigated the effects of a selective ET(A) receptor antagonist on hypoxic pulmonary hypertension in the mature horse. Horses were exposed to a 10 min period of hypoxia (F(I)O2 approximately 0.11) on 2 occasions, with and without pretreatment with the selective ET(A) receptor antagonist TBC11251 (10 mg/kg bwt i.v.). Hypoxia increased mean pulmonary artery pressure (PAP) from 18.3+/-0.9 (mean +/- s.e. normoxia) to 28.0+/-0.8 mmHg (hypoxia) in the session without ET(A) receptor antagonism. Carotid arterial pressure (CAP) also increased progressively throughout the period of hypoxic challenge and at the end was 153+/-5 mmHg (hypoxia) compared to during normoxia (140+/-5 mmHg). There was no significant overall effect of ET(A) receptor antagonism on the haemodynamic or ventilatory responses to acute hypoxia. However, between 5 and 10 min of hypoxia there was a trend for the mean PAP to diverge in the 2 treatments, which just failed to reach significance at 10 min of hypoxia (P = 0.053). In conclusion, this study describes the haemodynamic and ventilatory changes in response to a period of acute hypoxia in the adult horse. The results do not support a role for ET as a mediator of acute HPV in the horse, but suggest that it may be involved as a modulator or in the slower (>10 min) phase of HPV. [less ▲]

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See detailSymptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. A double blind, prospective, placebo-controlled study.
Appelboom, T; Schuermans, J; Verbruggen, G et al

in Scandinavian Journal of Rheumatology (2001), 30(4), 242-7

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ... [more ▼]

OBJECTIVES: We compare the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. METHODS: A multicenter, double blind, study comparing a daily intake of 300mg or 600mg of ASU and placebo. The study lasted 3 months and involved patients of both genders, aged 45 to 80 years and presenting with femoro-tibial knee osteoarthritis. The primary endpoint was NSAIDs and analgesics intake between D30 and D90. RESULTS: All efficacy parameters were significantly improved (p<0.01), in the two ASU groups compared to the placebo group. At D90, NSAIDs and analgesics intake decreased by more than 50% in 71% of the patients receiving ASU 300mg or 600mg, compared to 36% of the patients receiving placebo. From DO to D90 Lequesne's index dropped by 3.9 and 2.9 points in ASU 300mg and 600mg groups, respectively, against 1.6 in those receiving placebo. CONCLUSION: The efficacy of ASU at a dosage of 300mg/day and 600mg/day was consistently superior to that of placebo at all endpoints, with no differences observed between the two doses. [less ▲]

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See detailCombined Effects of Experimental Heavy-Metal Contamination (Cu, Zn, and CH3Hg) and Starvation on Quail's Body Condition: Parallelism with a Wild Common Guillemot (Uria aalge) Population Found Stranded at the Belgian Coast
Debacker, Virginie ULg; Rutten, Astrid; Jauniaux, Thierry ULg et al

in Biological Trace Element Research (2001), 82(1-3, Summer), 87-107

Combined effects of heavy-metal contamination (Cu, Zn, and CH3Hg) and starvation were tested on common quails (Coturnix coturnix japonica) and used as a model for comparison with a wild common guillemot ... [more ▼]

Combined effects of heavy-metal contamination (Cu, Zn, and CH3Hg) and starvation were tested on common quails (Coturnix coturnix japonica) and used as a model for comparison with a wild common guillemot (Uria aalge) population found stranded at the Belgian coast. Appropriate heavy-metal levels were given to the quails to obtain concentrations similar to those found in the seabirds's tissues. The contaminated animals were then starved for 4 d to simulate the evident malnutrition symptoms observed at the guillemot's level. In such conditions, food intake and total-body weight are shown to decrease in contaminated individuals with simultaneous significant hepatic and renal increase of the heavy-metal concentrations. Like guillemots, higher heavy-metal levels were observed in those contam- inated quails that had also developed a cachectic status characterized by a general atrophy of their pectoral muscle and complete absence of subcutaneous and/or abdominal fat depots. Although likely the result of a general protein catabolism during starvation, it is suggested that these higher metal levels could as well enhance a general muscle wasting process (cachectic status). [less ▲]

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See detailL'empreinte unitaire par coffrage métallo-résineux
Francois, Marcelle ULg; Lamy, Marc ULg

in Revue Belge de Médecine Dentaire = Belgisch Tijdschrift voor Tandheelkunde (2001), 56(3), 181-8

The metallic-resinous frame impression technique is based on the impression of single abutments encompassed in a global one, with or without transfert copings. For single tooth impression, this technique ... [more ▼]

The metallic-resinous frame impression technique is based on the impression of single abutments encompassed in a global one, with or without transfert copings. For single tooth impression, this technique is the easiest and the most practical alternative to the one using thermoplastic paste. The aim of this article is to describe, step-by-step, the impression taking procedures using the metallic-resinous frame technique. [less ▲]

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See detailCardiac surgery in octogenarians: who, when and how?
Pierard, Luc ULg

in European heart journal (2001), 22(14), 1159-61

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See detailA world monograph of the lichen genus Gyalectidium (Gomphillaceae)
Ferraro, Lidia Itati; Lücking, Robert; Sérusiaux, Emmanuël ULg

in Botanical Journal of the Linnean Society (2001), 137

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See detailLe Mésolithique du Bassin pannonien et la formation du Rubané
Otte, Marcel ULg; Noiret, Pierre ULg

in Anthropologie (L') (2001), 105(3, JUL-SEP), 409-419

The LBK appears as the result of acculturation of local Mesolithic Populations, beginning in the Pannonian Basin following a trans-Balkan colonisation. Economy, architecture and ceramic proceed from an ... [more ▼]

The LBK appears as the result of acculturation of local Mesolithic Populations, beginning in the Pannonian Basin following a trans-Balkan colonisation. Economy, architecture and ceramic proceed from an adaptation to local means, which explains the chronological disjunction between acculturation and geographic expansion. The whole is placed within a context already Indo-European, since the Late Palaeolithic. (C) 2001 Editions scientifiques et medicales Elsevier SAS. [less ▲]

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See detailHIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases.
Michiels, C.; Minet, E.; Michel, G. et al

in IUBMB Life (2001), 52(1-2), 49-53

HIF-1 is the main transcription factor responsible for increased gene expression in hypoxia: VEGF, erythropoietin, GLUT-1, and glycolytic enzymes are such target genes and all participate in the ... [more ▼]

HIF-1 is the main transcription factor responsible for increased gene expression in hypoxia: VEGF, erythropoietin, GLUT-1, and glycolytic enzymes are such target genes and all participate in the adaptative response of cells to hypoxia. AP-1 activation by hypoxia has also been demonstrated in several cell lines and it cooperates with HIF-1 for increasing VEGF gene transcription in hypoxia. Both HIF-1 and AP-1 activation by hypoxia seems to involve members of the MAP kinase family. Here, we summarize the data indicating that ERK and JNK are needed for activation of HIF-1 and AP-1, respectively. [less ▲]

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See detailLe polygraphe et les exigences de la preuve en matière pénale
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2001)

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See detailAnatomical characteristics of tension wood and opposite wood in young inclined stems of poplar (Populus euramericana cv ‘Ghoy’)
Jourez, Benoît ULg; Riboux, Alain; Leclercq, André

in IAWA Journal (2001), 22(2), 133-157

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of ... [more ▼]

Young shoots from poplar cuttings (P. euramericana cv ‘Ghoy’) were artificially inclined to 30° from vertical to quantify the anatomical modifications induced by this gravitational stimulus. At the end of the growing season, the tension wood tissue (from the upper face of the inclined axis) was compared to the opposite wood tissue (from the lower face), with radial position taken into account. On isolated elements after maceration, fibres and vessels were significantly longer in tension wood tissue. In the cross section, the gelatinous fibres had a smaller radial diameter than normal fibres in opposite wood. Vessel frequency and porosity were significantly lower in tension wood than opposite wood. Solitary vessels in tension wood were less circular in cross section than in opposite wood, but their surface area did not differ. Rays were more numerous in tension wood than opposite wood but their height did not differ between the two tissue types. Finally, there was a negative correlation between the proportion of vessels lumina (lowest in tension wood) and the proportion of fibres lumina including the G layer. The very controlled nature of this experiment (greenhouse, young clonal material, detailed anatomical observations within one growth ring) and the image analysis technology (allowing a large number of observations) enabled us to draw conclusions that may not have been seen in less-controlled experiments and/or those with smaller sample sizes. [less ▲]

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See detailLa réforme de la procédure fiscale : le point de vue de la Cour d’arbitrage
Orban, Lionel ULg

in Fiscalité 2001. Le point sur les réformes », Journée d’études du Mercredi 31 octobre 2001, organisée par le Service de droit fiscal de la Faculté de droit de l’Université de Liège (2001)

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See detailGlutathione S-transferases of Aulacorthum solani and Acyrthosiphon pisum: partial purification and characterization.
Francis, Frédéric ULg; Haubruge, Eric ULg; Gaspar, Charles ULg et al

in Comparative Biochemistry & Physiology Part B (2001), 129(1), 165-71

Glutathione S-transferases (GST) play an important role in the detoxification of many substances including allelochemicals from plants. Brassicaceae plants contain glucosinolates and emit volatile ... [more ▼]

Glutathione S-transferases (GST) play an important role in the detoxification of many substances including allelochemicals from plants. Brassicaceae plants contain glucosinolates and emit volatile isothiocyanates which affect the GST system. A comparison of the GST of two aphid species, the generalist Aulacorthum solani found on Brassicaceae and the Fabaceae specialist Acyrthosiphon pisum, was made to try to explain their respective feeding behaviour. Differences of GST were determined among the two aphid species based on purification by affinity chromatography, SDS-PAGE and on kinetic studies. Purification yields using an epoxy-activated Sepharose 6B column were highly different for the two aphid species (18% and 34% for A. solani and A. pisum, respectively). These variations were confirmed by SDS-PAGE. While only a 27-kDa band was observed for A. pisum, two bands of approximately 25-kDa were visualized for the generalist aphid, A. solani. Considering the kinetic results, differences of Km and Vmax were observed following the aphid species when a range of substrates (CDNB and DCNB) and GSH concentrations were tested. Studies on the detoxification enzymes of generalist and specialist herbivores would be undertaken to determine accurately the effect of the host plant on the organisms eating them, particularly in terms of biochemical and ecological advantages. [less ▲]

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See detailIonic or non-ionic contrast media during coronary intervention: does it make a difference?
Legrand, Victor ULg

in European heart journal (2001), 22(5), 353-4

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See detailUtilisation des gènes à effet majeur en sélection laitière. Un exemple: le gène Pit-1
Renaville, Robert ULg; Parmentier, Isabelle; Fontaine, Sandrine et al

in Les Elevages belges (2001), 4

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See detailPurification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis.
Brouta, F.; Descamps, F.; Fett, Thomas ULg et al

in Medical Mycology (2001), 39(3), 269-275

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by ... [more ▼]

A keratinolytic protease secreted by a feline clinical isolate of Microsporum canis cultivated in a broth containing feline keratin as the sole nitrogen source was purified from the culture filtrate by affinity chromatography on bacitracin-agarose and by hydrophobic chromatography on octyl-agarose. The enzyme had an apparent molecular mass of 43.5 kDa and the pI was 7.7. It had a significant activity against keratin azure, elastin-Congo red and denatured type I collagen (azocoll). Using the latter substrate, the optimum pH was around 8 and the apparent optimum temperature around 50 degrees C. The protease was strongly inhibited by 1,10-phenanthroline, phosphoramidon and EDTA. The first 13 N-terminal amino acid sequence showed a 61% homology with that of the extracellular metalloprotease of Aspergillus fumigatus and with the neutral protease I of A. oryzae, confirming that this 43.5 kDa keratinase is a metalloprotease. This keratinolytic metalloprotease could be a virulence-related factor involved in pathophysiological mechanisms of M. canis dermatophytosis. [less ▲]

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See detailEffect of Intravenous Platelet-Activating Factor on Bovine Pulmonary Mast Cells
Jolly, Sandra ULg; Thomas, Cédric; Genicot, Bruno et al

in Journal of Comparative Pathology (2001), 125(Aug-Oct), 81-89

The effect of platelet-activating factor (PAF) on bovine pulmonary mast cells (MCs) was investigated in calves aged 1-4 months. PAF was administered over a 5-min period at a rate of 50 ng/kg/min to six ... [more ▼]

The effect of platelet-activating factor (PAF) on bovine pulmonary mast cells (MCs) was investigated in calves aged 1-4 months. PAF was administered over a 5-min period at a rate of 50 ng/kg/min to six animals, which were killed approximately 10 min later. No macroscopical lesions were observed in the lung tissue of five control calves. On semi-thin toluidine-blue stained sections, MC cytoplasm showed profuse deep-blue granulation. In the lung tissues of PAF-treated calves, striking interstitial, alveolar and interlobular oedema and emphysema were observed. MC granules occurred at the periphery of the cytoplasm and MC nuclei were easily detectable. Moreover, the number of granules in the MC cytoplasm was remarkably low. A few granules with some metachromatic material were sometimes detected outside the cell limits. Ultrastructurally, the matrix pattern of the MC granules in lung tissues of control calves was either amorphous or granular. In lung tissues of the PAF-treated calves, the granular matrix pattern was pronounced, varying from fine- to coarse-grained, and the MCs were of reduced size, with many filiform processes and exocytotic vesicles. These findings indicate that pulmonary MC degranulation was induced by PAF in healthy calves. [less ▲]

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See detailComparison between the GIRBAS Scale and the Acoustic and Aerodynamic Measures Provided by EVA for the Assessment of Dysphonia following Unilateral Vocal Fold Paralysis.
Morsomme, Dominique ULg; Jamart, Jacques; Wery, Carine et al

in Folia Phoniatrica et Logopaedica (2001), 53(6), 317-25

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures ... [more ▼]

The aim of this study is to establish relevant objective parameters for evaluating dysphonia following unilateral vocal fold paralysis. To do so, the study compares objective and perceptual voice measures. The objective measures were obtained using a voice analysis software (Evaluation Vocale Assistee), whereas the perceptual measures were established with the GIRBAS Scale (grade, instability, roughness, breathiness, asthenia, and strain). All measurements were performed on 40 voice samples: 28 dysphonic subjects with unilateral laryngeal paralysis, and 12 control subjects. The intra- and inter-judge agreements were fairly good, at least for control subjects. The six GIRBAS measures obtained from the pathological voices were higher than those from the control voices (p < 0.001) and the correlation between both groups was good. Grade, breathiness and asthenia correlated with the objective parameters that express the aperiodicity of the phonatory signal (p < 0.01), namely, the coefficient of variability of the fundamental frequency, the coefficient of variability of intensity, and jitter. Our findings suggest that the perceptual reality of laryngeal paralysis-induced dysphonia depends more on grade, breathiness and asthenia than it does on roughness or instability. [less ▲]

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See detailRandom matrix study of the phase structure of QCD with two colors
Vanderheyden, Benoît ULg; Jackson, A. D.

in Physical Review. D : Particles and Fields (2001), 64(7), 074016

We apply a random matrix model to the study of the phase diagram of QCD with two colors, two flavors, and a small quark mass. Although the effects of temperature are only included schematically, this ... [more ▼]

We apply a random matrix model to the study of the phase diagram of QCD with two colors, two flavors, and a small quark mass. Although the effects of temperature are only included schematically, this model reproduces most of the ground state predictions of chiral perturbation theory and also gives a qualitative picture of the phase diagram at all temperatures. It leads, however, to an unphysical behavior of the chiral order parameter and the baryon density in vacuum and does not support diquark condensation at arbitrarily high densities. A better treatment of temperature dependence leads to correct vacuum and small temperature properties. We compare our results at both high and low densities with the results of microscopic calculations using the Nambu-Jona-Lasinio (NJL) model and discuss the effects of large momentum scales on the variations of condensation fields with chemical potential. [less ▲]

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See detailVies et Miracles de Domitien Deuxième partie
George, Philippe ULg

in Analecta Bollandiana : Revue Critique d’Hagiographie = A Journal of Critical Hagiography (2001), CXIX

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See detailCompte-rendu de Daniel Giovannangeli, Le retard de la conscience. Husserl, Sartre, Derrida
Leclercq, Bruno ULg

in Recherches Husserliennes (2001), 16

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See detailFusariose disséminée chez un patient immunodéprimé
QUATRESOOZ, Pascale ULg; Meiers, I.; ARRESE ESTRADA, Jorge ULg et al

in Revue de l’Association Belge des Technologues de Laboratoire = Tijdschrift van de Belgische Vereniging van Laboratoriumtechnologen (2001), 28

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See detailUn exemple de gestion originale de la nature : la restauration de forêts alluviales de l’Elbe
Claessens, Hugues ULg

in Parcs & Réserves (2001), 56(1), 23-25

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See detailThe use of additives to prepare low-density xerogels
Alié, Christelle ULg; Pirard, René ULg; Lecloux, A. J. et al

in Journal of Non-Crystalline Solids (2001), 285

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See detailLocation and Phenotype of Proliferating T cells in Secondary Lymph Follicles
Hoshi, S.; Bouzahzah, F.; Mancini, I. et al

in Journal of Clinical and Experimental Hematopathology [=JCEH] (2001), 42

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See detailCompte rendu de Frédéric Barbier, Histoire du livre
Durand, Pascal ULg

in Bulletin des Bibliothèques de France (2001), 46/4

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See detailAssociations between casein haplotypes and first lactation milk production traits in Finnish Ayrshire cows
Ikonen, T.; Bovenhuis, H.; Ojala, M. et al

in Journal of Dairy Science (2001), 84(2), 507-514

The objective of this study was to estimate the effects of ß--casein (CN) haplotypes on first-lactation milk production traits. The ß--CN haplotypes were deduced using information on ß- and -CN genotypes ... [more ▼]

The objective of this study was to estimate the effects of ß--casein (CN) haplotypes on first-lactation milk production traits. The ß--CN haplotypes were deduced using information on ß- and -CN genotypes of cows and their sires for 16,973 Finnish Ayrshire cows that had at least nine paternal half sibs. Effects of CN haplotypes on milk production traits were estimated for one haplotype at a time using an animal model, which included the fixed effects for calving year and month, age at calving, days open, ß-lactoglobulin, and a ß--CN haplotype. Differences in milk production traits were also estimated between haplotype combinations A1A+A2B and A1B+A2A within ß--CN genotype A1A2AB and between combinations A1E+A2A and A1A+A2E within genotype A1A2AE. The ß--CN haplotypes A2A and A2B were associated with high milk and protein yields and low fat content, and those that included the ß-CN A1 allele were associated with low yields and high fat content. Protein content was affected by the -CN locus; haplotype A1B was associated with high protein content and A1E was with low protein content. The haplotype combination A1A+A2B was associated with 140 kg more milk yield (P = 0.045) and 0.03 percentage units less protein content (P = 0.055) than combination A1B+A2A, and combination A1A+A2E showed 0.02 percentage units greater protein content (P = 0.098) than A1E+A2A. These results indicate that genes linked to the CN loci contribute to the variation in milk yield and protein content. [less ▲]

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See detailc-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells.
Minet, E.; Michel, G.; Mottet, Denis ULg et al

in Experimental Cell Research (2001), 265(1), 114-24

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors ... [more ▼]

Hypoxia is an important pathophysiological stress that occurs during blood vessel injuries and tumor growth. It is now well documented that hypoxia leads to the activation of several transcription factors which participate in the adaptive response of the cells to hypoxia. Among these transcription factors, AP-1 is rapidly activated by hypoxia and triggers bFGF, VEGF, and tyrosine hydroxylase gene expression. However, the mechanisms of AP-1 activation by hypoxia are not well understood. In this report, we studied the events leading to AP-1 activation in hypoxia. We found that c-jun protein accumulates in hypoxic HepG2 cells. This overexpression is concomitant with c-jun phosphorylation and JNK activation. Moreover, we showed that AP-1 is transcriptionally active. We also observed that AP-1 transcriptional activity is inhibited by a MEKK1 dominant negative mutant. Moreover, the MEKK1 dominant negative mutant as well as deletion of the AP-1 binding sites within the c-jun promoter inhibited the c-jun promoter activation by hypoxia. All together, these results indicate that, in hypoxic HepG2 cells, AP-1 is activated through a JNK-dependent pathway and that it is involved in the regulation of the c-jun promoter, inducing a positive feedback loop on AP-1 activation via c-jun overexpression. [less ▲]

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See detailOviposition preferences of Episyrphus balteatus.
Vanhaelen, Nicolas; Haubruge, Eric ULg; Gaspar, Charles ULg et al

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (2001), 66(2a), 269-75

A crucial aspect of predator oviposition behaviour is host plant choice, especially in hoverflies where the newly hatched offspring are unable to move a great distance to search for the appropriate prey ... [more ▼]

A crucial aspect of predator oviposition behaviour is host plant choice, especially in hoverflies where the newly hatched offspring are unable to move a great distance to search for the appropriate prey. Such offspring must generally feed on the host plant aphids previously selected by the mother. Some factors involved in the selection of the oviposition site of Episyrphus balteatus De Geer include aphids associated to chemical stimuli, aphid colony size and host plant characteristics. Here we tested the hypothesis that there will not only be a rank order hierarchy of preference for aphid prey species reared on the same host plant but that a similar hierarchy of different host plant of one aphid species could be established. Therefore we compared the number of eggs laid on different combinations of host plant and aphid species. Vicia faba L., secondary metabolites free, Brassica napus L. and Sinapis alba L., containing low and high levels of glucosinolates respectively were used. The latter compounds are well known allelochemicals from Brassicaceae having a strong influence on specialist and generalist insects from both phytophagous and entomophagous levels. These experiments enhance the importance of tritrophic interactions in biological control of pests by underlining the host plant influence on aphidophagous predators, either directly or through the odours emitted by the phytophagous prey. [less ▲]

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See detailImplication de la neurohypophyse dans le stress psychique
Scantamburlo, Gabrielle ULg; Ansseau, Marc ULg; Legros, Jean-Jacques ULg

in Encéphale (L') (2001), 27(3, May-Jun), 245-59

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various ... [more ▼]

Effects of different psychological stimuli on oxytocin (OT) and vasopressin (AVP) secretion are reviewed in animals and in humans. The secretion of neuropituitary hormones is also discussed in various psychiatric diseases such an anorexia nervosa, bipolar disorder, schizophrenia and obsessive-compulsive disorder. AVP and OT are secreted into the hypophyseal portal circulation by neurons which project from the paraventricular nucleus to the external zone of the median eminence. AVP and OT-containing neurons in the suprachiasmatic and paraventricular nuclei project to limbic areas, including the hippocampus, the subiculum, the ventral nucleus of the amygdala and the nucleus of the diagonal band. Specific AVP receptors which are pharmacologically different from the pressor and antidiuretic AVP receptors have been found in the anterior pituitary. OT receptors have been identified in a variety of forebrain sites. The neurohypophyseal secretion is regulated by the cholinergic muscarinic, histaminergic and beta-adrenergic systems. Stress alters the secretion of one or more of the hypothalamic factors which interact at the pituitary to increase the secretion of ACTH. AVP and OT have been shown to modulate the effect of Corticotropin-Releasing Factor (CRF) on ACTH secretion and appear to play a key role in mediating the ACTH response to stress. Although AVP is a relatively weak secretagogue for ACTH, it markedly potentiates the activity of CRF both in vitro and in vivo. The role of OT is more complex. In vitro, OT stimulates ACTH release at high doses whereas in human it inhibits ACTH secretion at low doses. The type of stressor appear to determine the relative importance of these secretatogues in ACTH response. Several recent studies indicate that psychological stressors display a similar degree of variety of secretagogue release patterns as was found earlier for physical stressors. A bewildering array of technique produces a bewildering array of conclusions. In rats, OT may be an important secretagogue during a novel stimulus, whereas the role for AVP is less clear. Indeed two studies out of ten suggest a stimulating role for AVP. In response to frustration and submission, OT and AVP are secreted. Regarding social isolation, results are difficult to interpret and the role of AVP could be species-dependent. In contrast plasma OT levels do not change. After restraint, ACTH release is primarily mediated by the active increase of OT and AVP does not appear to play a role. When restraint is associated with moderate levels of physical components and during immobilisation, all two secretagogs are involved in the ACTH response. With fear, ACTH response appears to be driven by OT. In humans, one study indicates that high emotionality women increase plasma OT in response to uncontrollable noise. Various neuroendocrine dysregulations have been observed in psychiatric disease. Either an increase or a decrease of the hypothalamic-pituitary-adrenal (HPA) function have been described in several illnesses. Effects of OT appear to be reciprocal to the effects of AVP. OT has been called the "amnestic" neuropeptide due to its capacity to attenuate memory consolidation and retrieval. AVP exhibits a central activating action on mood, memory and selective attention. Underweight patients with anorexia nervosa have abnormally high levels of centrally directed AVP and reduced OT levels. These modifications could enhance the retention of cognitive distortions of aversive consequences of eating. Patients with bipolar disorder show a biphasic secretion of AVP. Depressive episodes are associated with decreased vasopressinergic activity whereas manic episodes involve an increased release. AVP might be responsible for an increased catecholamine activity. In addition, lithium could act as an antagonist to AVP. In schizophrenic patients, studies using the apomorphine stimulation suggest increased oxytoninergic and decreased vasopressinergic functions. These findings are consistent with the beneficial role of AVP on schizophrenic symptoms noted in several trials. The increased OT could be responsible for "positive" symptomatology such as delusions and hallucinations. Obsessive compulsive disorder (OCD) includes a range of cognitive and behavioral disturbances that could be influenced by OT. In animals, several studies have emphasized the role of AVP in promoting repetitive grooming behaviors and maintaining conditioned response to aversive stimuli. In OCD patients, one study have reported that AVP/OT ratio was negatively correlated with symptom severity. However, an independent report found similar AVP concentrations in OC patients without a personal or family history of tic disorder and in normal subjects. Whether these modifications are only a consequence of the central disturbances or whether those peptides could participate in the pathogenesis of these affections remains to be elucidated. [less ▲]

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See detailWILSON "BOOZOO" CHAVIS - nécrologie
Sacré, Robert ULg

in Soul Bag (2001), (163), 42-43

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See detailAb initio simulations of liquid semiconductors using the pseudopotential-density functional method
Chelikowsky, J. R.; Derby, J. J.; Godlevsky, V. V. et al

in Journal of Physics : Condensed Matter (2001), 13(41), 817-854854

One of the most difficult problems in condensed matter physics is describing the microscopic nature of the liquid state. Owing to the dynamical nature of the liquid state, it is not possible to discuss a ... [more ▼]

One of the most difficult problems in condensed matter physics is describing the microscopic nature of the liquid state. Owing to the dynamical nature of the liquid state, it is not possible to discuss a particular microscopic structure; only ensemble averages can be specified. Such averages can be performed via well crafted molecular dynamics simulations: the length of the simulation, the size of the ensemble and the nature of the interatomic forces must all be carefully analysed. Historically, a problematic issue in doing such simulations is that of how to describe the interatomic forces in the liquid state. This matter is especially challenging for the melt of semiconductors, such as silicon or gallium arsenide, where the chemical bond contains a strong covalent component. It is difficult to use pairwise interatomic potentials in such cases. Although many-body potentials can be utilized for simulations of these materials, one must map quantum phenomena such as hybridization onto classical interatomic potentials. This mapping is complex and difficult. In this review, we illustrate how one can avoid this problem by utilizing quantum forces to simulate liquids. Our focus is on the pseudopotential-density functional method. Within the pseudopotential method, only the valence electrons are explicitly treated and within the density functional theory, exchange and correlation terms are mapped onto an effective one-electron potential [less ▲]

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See detailRole of β-Oxidation Enzymes in γ-Decalactone Production by the Yeast Yarrowia lipolytica
Waché, Y.; Aguedo, Mario ULg; Choquet, A. et al

in Applied and Environmental Microbiology (2001), 67(12), 5700-5704

Some microorganisms can transform methyl ricinoleate into γ-decalactone, a valuable aroma compound, but yields of the bioconversion are low due to (i) incomplete conversion of ricinoleate (C18) to the C10 ... [more ▼]

Some microorganisms can transform methyl ricinoleate into γ-decalactone, a valuable aroma compound, but yields of the bioconversion are low due to (i) incomplete conversion of ricinoleate (C18) to the C10 precursor of γ-decalactone, (ii) accumulation of other lactones (3-hydroxy-γ-decalactone and 2- and 3-decen-4-olide), and (iii) γ-decalactone reconsumption. We evaluated acyl coenzyme A (acyl-CoA) oxidase activity (encoded by the POX1 through POX5 genes) in Yarrowia lipolytica in lactone accumulation and γ-decalactone reconsumption in POX mutants. Mutants with no acyl-CoA oxidase activity could not reconsume γ-decalactone, and mutants with a disruption of pox3, which encodes the short-chain acyl-CoA oxidase, reconsumed it more slowly. 3-Hydroxy-γ-decalactone accumulation during transformation of methyl ricinoleate suggests that, in wild-type strains, β-oxidation is controlled by 3-hydroxyacyl-CoA dehydrogenase. In mutants with low acyl-CoA oxidase activity, however, the acyl-CoA oxidase controls the β-oxidation flux. We also identified mutant strains that produced 26 times more γ-decalactone than the wild-type parents. [less ▲]

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See detailPerspectives de vaccination anti-dermatophytique chez les carnivores domestiques
Descamps, F.; Brouta, F.; Losson, Bertrand ULg et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailSurvival, gap formation and recovery dynamics in grassland ecosystems exposed to heat extremes: the role of species richness.
Van Peer, L; Nijs, I; Bogaert, Jan ULg et al

in Ecosystems (2001), 4(8), 797-806

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See detailSurface Modification of Polycarbonate and Poly(ethyleneterephthalate) Films and Membranes by Polyelectrolyte Deposition
Dauginet, Laurence; Duwez, Anne-Sophie ULg; Legras, Roger et al

in Langmuir (2001), 17

The surface modification by chemical or physical adsorption of a polyelectrolyte (polyallylamine, PAH) was established using hydrolyzed polycarbonate (PC) and poly(ethylene terephthalate) (PET) thick and ... [more ▼]

The surface modification by chemical or physical adsorption of a polyelectrolyte (polyallylamine, PAH) was established using hydrolyzed polycarbonate (PC) and poly(ethylene terephthalate) (PET) thick and thin films. Contact angle data indicated changes in the hydrophilicity of PET film surfaces in terms of the chemical treatment. XPS analysis showed that the immobilization of PAH on PET and PC films was effective and that the amount of chemically or/and physically bounded PAH depends on the pH of the electrolyte solution used for the adsorption. Similar treatments have been successfully applied to polymeric track-etched membranes. These modified membranes have been used as templates for the synthesis of polypyrrole (PPy) nanotubules. FE-SEM analysis showed that much thicker PPy tubules were obtained in modified membranes than in virgin ones. This indicates that the surface chemistry of the pore walls plays an important role in the morphology of the nanostructures synthesized within the pores [less ▲]

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See detailLe portage asymptomatique de Microsporum canis chez le chat
Mignon, Bernard ULg; Brouta, F.; Descamps, F. et al

in Annales de Médecine Vétérinaire (2001), 145

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See detailImpaired emotional facial expression in alcoholism compared with obsessive compulsive disorder and normal controls
Kornreich, C; Blairy, Sylvie ULg; Philippot, P et al

in Psychiatry Research (2001), 102

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See detailN N scattering phase shifts in a chiral constituent quark model
Bartz, Daniel ULg; Stancu, Floarea ULg

in Nuclear Physics A (2001), A688

We study the nucleon-nucleon interaction within a chiral constituent quark model which reproduces succesfully the baryon spectra. We calculate the $^3S_1$ and $^1S_0$ phase shifts by using the resonating ... [more ▼]

We study the nucleon-nucleon interaction within a chiral constituent quark model which reproduces succesfully the baryon spectra. We calculate the $^3S_1$ and $^1S_0$ phase shifts by using the resonating group method. They clearly indicate the presence of a strong repulsive interaction at short distance, due to the spin-flavour symmetry of the quark-quark interaction and of the quark interchange between the two interacting nucleons. A $\sigma$-meson exchange quark-quark interaction, providing a medium-range attraction, helps to get closer to the experimental phase shifts. [less ▲]

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See detailQuelle biodiversite pour nos lisieres forestieres?
Branquart, E.; Doucet, Jean-Louis ULg; Liesse, D. et al

in Parcs & Réserves (2001), 56(1), 26-32

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See detailIntracellular pH-dependent efflux of the fluorescent probe pyranine in the yeast Yarrowia lipolytica
Aguedo, Mario ULg; Waché, Y.; Belin, J.-M.

in FEMS Microbiology Letters (2001), 200(2), 185-189

8-Hydroxypyrene-1,3,6-trisulfonic acid (pyranine) can be used as a vital intracellular pH (pHi) indicator. In the yeast Yarrowia lipolytica, a partial efflux of the probe was detected by using the pH ... [more ▼]

8-Hydroxypyrene-1,3,6-trisulfonic acid (pyranine) can be used as a vital intracellular pH (pHi) indicator. In the yeast Yarrowia lipolytica, a partial efflux of the probe was detected by using the pH-independent wavelength of 415 nm. A simplified correction of the fluorescent signals was applied, enabling to show for this species a good near-neutral pHi maintenance capacity in a pH 3.9 medium. Octanoic acid, which is known to have toxic effects on yeast, decreased the pHi and increased the 260-nm-absorbing compounds leakage. However, this acid inhibited the fluorescent probe efflux linearly with its concentration suggesting a pHi-dependent efflux of pyranine from cells. © 2001 Federation of European Microbiological Societies. [less ▲]

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See detailResidual circulation and thermohaline distribution of the Ria de Vigo: a 3-D hydrodynamical model
Lopez, S. T.; Varela, R. A.; Delhez, Eric ULg

in Scientia Marina (2001), 65(Suppl. 1), 277-289

A three-dimensional, non-linear, baroclinic model is described and tested for the first time to study the residual circulation and the thermohaline distribution of the Ria de Vigo (NW Spain) at short time ... [more ▼]

A three-dimensional, non-linear, baroclinic model is described and tested for the first time to study the residual circulation and the thermohaline distribution of the Ria de Vigo (NW Spain) at short time scales and under different wind stress regimes. Two markedly different realistic scenarios were chosen: northerly upwelling-favourable winds and southerly downwelling-favourable winds. The numerical experiments carried out indicate that the hydrodynamic regime of the Ria de Vigo is mostly a consequence of wind events. As could be expected, moderately strong North winds reinforce the normal (positive) Ria circulation, while winds blowing from the South, when sufficiently strong, reverse the typical circulation pattern and reduce the characteristic outgoing velocities and the flushing time inside the Ria. The temperature and salinity fields generated by the model in both situations were compared with observations and found to be in qualitatively good agreement, supporting the 3D velocity field distribution. [less ▲]

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See detailEffect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group.
McClung, M R; Geusens, P; Miller, P D et al

in New England Journal of Medicine [=NEJM] (2001), 344(5), 333-40

BACKGROUND: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. METHODS: We studied 5445 women 70 to 79 years old who had osteoporosis ... [more ▼]

BACKGROUND: Risedronate increases bone mineral density in elderly women, but whether it prevents hip fracture is not known. METHODS: We studied 5445 women 70 to 79 years old who had osteoporosis (indicated by a T score for bone mineral density at the femoral neck that was more than 4 SD below the mean peak value in young adults [-4] or lower than -3 plus a nonskeletal risk factor for hip fracture, such as poor gait or a propensity to fall) and 3886 women at least 80 years old who had at least one nonskeletal risk factor for hip fracture or low bone mineral density at the femoral neck (T score, lower than -4 or lower than -3 plus a hip-axis length of 11.1 cm or greater). The women were randomly assigned to receive treatment with oral risedronate (2.5 or 5.0 mg daily) or placebo for three years. The primary end point was the occurrence of hip fracture. RESULTS: Overall, the incidence of hip fracture among all the women assigned to risedronate was 2.8 percent, as compared with 3.9 percent among those assigned to placebo (relative risk, 0.7; 95 percent confidence interval, 0.6 to 0.9; P=0.02). In the group of women with osteoporosis (those 70 to 79 years old), the incidence of hip fracture among those assigned to risedronate was 1.9 percent, as compared with 3.2 percent among those assigned to placebo (relative risk, 0.6; 95 percent confidence interval, 0.4 to 0.9; P=0.009). In the group of women selected primarily on the basis of nonskeletal risk factors (those at least 80 years of age), the incidence of hip fracture was 4.2 percent among those assigned to risedronate and 5.1 percent among those assigned to placebo (P=0.35). CONCLUSIONS: Risedronate significantly reduces the risk of hip fracture among elderly women with confirmed osteoporosis but not among elderly women selected primarily on the basis of risk factors other than low bone mineral density. [less ▲]

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See detailGenotypical and phenotypical characterization of potential virulence of intestinal avian Escherichia coli strains isolated in Algeria
Mellata, M.; Bakour, R.; Jacquemin, E. et al

in Avian Diseases (2001), 45

In order to characterize potential pathogenic Escherichia coli strains isolated from diarrheic hens and chickens originating from intensive battery rearing in North Algeria, the presence of a large range ... [more ▼]

In order to characterize potential pathogenic Escherichia coli strains isolated from diarrheic hens and chickens originating from intensive battery rearing in North Algeria, the presence of a large range of virulence factors and markers was studied in 50 strains by DNA-DNA hybridization on colonies and phenotypic tests. The sequences we focused on were those coding for adhesins F5, F41, F17, Pap, Afa, and Sfa; intimin Eae; and toxins STa, STb, LT1, Stx1, Stx2, CNF1, and CNF2. The phenotypes explored were the colicins, aerobactin, hemolysins, and hemagglutinin production and serum resistance. The genotypic and phenotypic tests enabled us to categorize the isolates into two distinct groups: those with a potential to invade the host (27 strains were serum resistant and/or produced aerobactin), among which three strains were also potentially diarrheagenic, one strain was LT1 + F17+ Afa+ Pap+ (enterotoxigenic E. coli) and the two others were Stx1 (verotoxigenic E. coli). Twenty-three strains were colicinogenic, including 19 strains producing colicin V. This latter factor was also detected in isolates negative for the other virulence factors. On the basis of the type of erythrocytes agglutinated, we established 14 mannose-resistant hemagglutination patterns among the 37 strains tested, including 22 serum-resistant and/or aerobactin producing strains and 15 strains negative for these two characters. None of the strains produced alpha hemolysin, whereas two strains produced beta hemolysin and enterohemolysin, respectively. Congo red fixation was observed in 25 strains. No relationship could be detected between Congo red fixation and the presence of other virulence markers, such as serum resistance and aerobactin production. This study shows that among isolates originating from the feces of diarrheic chickens, the proportion of potentially diarrheagenic E. coli strains is low. [less ▲]

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See detailIntégration régionale et démocratie. Quelques réflexions à partir de la pensée d'Alexis de Tocqueville
Carlier, Jean-Yves ULg

in Revue Burkinabè du droit (2001), (39-40), 9-20

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See detailBreakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes.
Berghmans, S.; SEGERS, Karin ULg; Shay, T. et al

in Mammalian Genome : Official Journal of the International Mammalian Genome Society (2001), 12(2), 183-5

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See detailGene structure and promoter function of a teleost ribosomal protein: a tilapia (Oreochromis mossambicus) L18 gene
Molina, Alfredo; Iyengar, Arati; Marins, Luis F. et al

in Biochimica et Biophysica Acta (2001), 1520(3), 195-202

We have cloned and characterized a tilapia (Oreochromis mossambicus) L18 ribosomal protein gene, including the complete transcribed region and 488 bp of upstream regulatory sequences. We have also ... [more ▼]

We have cloned and characterized a tilapia (Oreochromis mossambicus) L18 ribosomal protein gene, including the complete transcribed region and 488 bp of upstream regulatory sequences. We have also isolated two L18 cDNAs from another tilapia (Oreochromis niloticus) with a few conservative nucleotide differences. Our results suggest the presence of two genes in both species. Reporter constructs were tested for transient expression in CV1 cells and in microinjected zebrafish and tilapia embryos. The tilapia L18 promoter was able to drive expression of the reporter gene in all three experiments, with no apparent preference for a particular tissue. The tilapia L18 promoter is therefore likely to be a powerful tool to drive tissue-independent gene expression in fish. [less ▲]

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See detailProfils de la progestérone des vaches zébu ‘Azawak’ et taurin ‘Gourunsi’ après induction de l’œstrus aux progestagènes combinés à la prostaglandine
Zongo, M.; Pitala, W.; Boly, H. et al

in Tropicultura (2001), 19(3), 131-134

Un dosage radioimmunologique a été utilisé pour mesurer les concentrations de progestérone chez les zébus “Azawak” (Bos indicus, n = 6) et taurins Gourunsi (Bos taurus, n = 5) après induction de l'œstrus ... [more ▼]

Un dosage radioimmunologique a été utilisé pour mesurer les concentrations de progestérone chez les zébus “Azawak” (Bos indicus, n = 6) et taurins Gourunsi (Bos taurus, n = 5) après induction de l'œstrus. Les observations ont été menées sur 11 vaches non gestantes (groupe I composé de 3 zébus Azawak et 3 taurins Gourunsi; groupe II composé de 3 zébus Azawak et 2 taurins Gourunsi), soumises à un traitement hormonal reposant sur l’administration d’un implant de progestagène, d’une injection de prostaglandine F2alpha et, pour une partie des femelles (groupe I), d’une injection de PMSG. Les implants ont été placés sous la peau de la face externe de l’oreille et maintenus pendant une période de 10 jours. Au 8e jour du traitement, les femelles ont reçu une injection intramusculaire de prostaglandine F2 (5 mg/100 kg) et au 10e jour, au moment du retrait, une injection de PMSG (400 UI/300 kg de poids vif) a été pratiquée sur les animaux du groupe I. Chez les taurins Gourunsi et chez les zébus Azawak ayant reçu l’injection de PMSG, le traitement a été suivi d’un œstrus dans 2 cas sur 3. Chez les animaux appartenant au groupe II, l’œstrus ne fut observé chez aucun taurin et seulement chez 1 des 3 zébus. Les concentrations de progestérone mesurées au cours des phases lutéales qui ont suivi sont restées faibles chez les taurins Gourunsi. Chez les zébus Azawak, les concentrations se sont révélées plus élévées chez les femelles ayant reçu l’injection de PMSG (6,0 +/- 1,2 ng/ml) que chez celles qui n’avaient pas reçu (3,2 +/- 0,8 ng/ml). [less ▲]

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See detailThe effect of risedronate on hip fracture risk in elderly women with osteoporosis
Bensen, W; Eastell, R; Reginster, Jean-Yves ULg et al

in Journal of Rheumatology (2001), 28(S63), 24

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See detailLes surcoûts de l’étalement urbain en Wallonie
Halleux, Jean-Marie ULg

in Etudes Foncières (2001), (94), 18-21

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See detailL'avenir de l'enseignement
de Landsheere, Gilbert ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2001), (5-6), 59-78

Ce texte, issu de la discussion générale qui a eu lieu dans le cadre du congrès 'La Wallonie au Futur. Le défi de l'éducation' (Namur, octobre 1991), a été publié en 1992. Son ossature est due à la plume ... [more ▼]

Ce texte, issu de la discussion générale qui a eu lieu dans le cadre du congrès 'La Wallonie au Futur. Le défi de l'éducation' (Namur, octobre 1991), a été publié en 1992. Son ossature est due à la plume de Gilbert de Landsheere, mais il intègre aussi les apports d'autres collègues, comme Anne Van Haecht (ULB), Gérard Fourez (FUNDP) et Jean-Pierre Pourtois (UMH). Il ne faut pas dès lors s'étonner de certaines références faites à un présent actuellement 'vieux d'une dizaine d'années' ou à un futur 'qui est peut-être déjà révolu!'. Nous avons en effet conservé le texte sans y apporter la moindre modification. Il nous semblait intéressant de permettre à chacun de faire le point sur une décennie à partir de cette contribution. [less ▲]

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See detailThe behavioral effects of acute and chronic JL 13, a putative antipsychotic, in Cebus non-human primates
Casey, Daniel; Bruhwyler, Jacques; Delarge, Jacques et al

in Psychopharmacology (2001), 157

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See detailAn algorithm and a method to search bifurcation points in non-linear problems
Chambon, René; Crochepeyre, Stéphane; Charlier, Robert ULg

in International Journal for Numerical Methods in Engineering (2001), 51(3), 315-332

This paper is devoted to a numerical method able to help the determination of the bifurcation threshold in non-linear time-independent continuum mechanic problems. First, some theoretical results about ... [more ▼]

This paper is devoted to a numerical method able to help the determination of the bifurcation threshold in non-linear time-independent continuum mechanic problems. First, some theoretical results about uniqueness are recalled. In the framework of the large-strain assumption, the differences between the classical finite-step problem and the rate problem are presented. An iterative algorithm able to solve the rate problem is given. Using different initializations, it is seen in some numerical experiments that it is possible with this algorithm to get different solutions when the underlying mathematical problem solved does not enjoy a uniqueness property. The constitutive equations used have been chosen to be simple enough to deduce some theoretical knowledge about the corresponding uniqueness problems. Finally, a method is given which is able in some case to give an upper bound of the bifurcation threshold. Copyright (C) 2001 John Wiley & Sons, Ltd. [less ▲]

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See detailEvolution of aphidophagous ladybird populations in a vegetable crop and implications as biological agents.
Francis, Frédéric ULg; Colignon, P.; Hastir, P. et al

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (2001), 66(2a), 333-40

Aphidophagous predators such as hoverfly and ladybird beetles are effective biological agents to control aphid pests in perennial and annual cultivated species. Introduction and conservation of beneficial ... [more ▼]

Aphidophagous predators such as hoverfly and ladybird beetles are effective biological agents to control aphid pests in perennial and annual cultivated species. Introduction and conservation of beneficial insects are two ways to increase natural control of pests. Whether massive releases of entomophagous insects are expensive and time consuming, the preservation of predator natural populations can be expected by reducing and by adapting chemical treatments in crop fields. Vegetable cultivated areas increased in Belgium for several years, mainly Fabaceae species such as peas and beans. In this work, the evolution of ladybird species population was assessed from May to June in broad bean fields (Vicia faba L.) between Waremme and Hannut, in Hesbaye. Weekly, the aphid and aphidophagous beetle populations were collected from yellow traps and determined on plants by visual observations. Even if five ladybird species were identified, three of them represented more than 95% of the collected insects (Coccinella septempunctata L., Propylea quatuor-decimpunctata L. and Psyllobora vingintiduopunctata L.). Evolution of coccinellid populations during the cultivation season was discussed in relation to the presence of potential aphid preys and the agrochemical treatments which were applied. Integrated pest management in vegetable fields constitute a reliable way to increase the quality level of fresh vegetables in terms of pesticide residue limitations. [less ▲]

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See detailQuelle réparation de l'accident de travail mortel est-elle réservée au concubin? Une réponse attendue de la Cour d'Arbitrage.
Michiels, Olivier ULg; Joskin, Véronique

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2001)

Cette note aborde la quesiton suivante : L'article 12 de la loi du 12 avril 1971 relative aux accidents du travail viole-t-il les articles 10 et 11 de la Constitution en ce qu'il réserve le bénéfice d'une ... [more ▼]

Cette note aborde la quesiton suivante : L'article 12 de la loi du 12 avril 1971 relative aux accidents du travail viole-t-il les articles 10 et 11 de la Constitution en ce qu'il réserve le bénéfice d'une rente viagère au conjoint ni divorcé, ni séparé de corps ainsi qu'au conjoint divorcé ou séparé de corps qui bénéficiait d'une pension alimentaire à charge de la victime ? [less ▲]

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See detailGenetics of menopause-associated diseases.
Massart, François ULg; REGINSTER, Jean-Yves ULg; Brandi, M L

in Maturitas (2001), 40(2), 103-16

Menopause is the permanent cessation of menstruation resulting from the loss of ovarian follicular activity. It is estimated that perhaps 50 million women worldwide will go into menopause annually ... [more ▼]

Menopause is the permanent cessation of menstruation resulting from the loss of ovarian follicular activity. It is estimated that perhaps 50 million women worldwide will go into menopause annually. Atherosclerotic cardiovascular disease, osteoporotic fractures and Alzheimer's dementia are common chronic disorders after menopause, representing major health problems in most developed countries. Apart from being influenced by environmental factors, these chronic disorders recognize a strong genetic component, and there are now considerable clinic evidences that these disorders are related to low hormonal milieu of postmenopausal women. Here, we review up-to-date available data suggesting that genetic variation may contribute to higher susceptibility to four sporadic chronic syndromes such as osteoporosis (OP), osteoarthritis (OA), Alzheimer's disease (AD) and coronary artery disease (CAD). For these four syndromes candidate genes that today appear as major loci in genetic susceptibility encode for proteins specific of a given system, as the vitamin D receptor (VDR) gene for the skeleton and, therefore, OP or angiotensin converting enzyme (ACE) for the cardiovascular system and, therefore, CAD. The investigation of gene polymorphisms in various pathological conditions typical of postmenopause offer an explanation not only of their genetic inheritance but also of their co-segregation in given individuals. In this view, it may be possible to identify a common set of genes whose variants contribute to a common genetic background for these different disorders. Ideal candidates appear genes of the estrogen response cascade [i.e. estrogen receptor (ERs), enzymes involved in estrogen metabolism or co-activators and co-inhibitors]. All together this information may represent the basis both for future recognition of individuals at risk and for the pharmacogenetic driving of drug responsiveness. [less ▲]

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See detailLe portfolio : un outil de socio-construction pour scripteur en devenir
Baye, Ariane ULg; Denooz, Régine

in Caractères (2001), 3

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See detailAbout the Photoionization of Methyl Chloride. A Threshold Photoelectron Spectroscopic and Photoionization Mass Spectrometric investigation.
Locht, Robert ULg; Leyh, Bernard ULg; Hoxha, A. et al

in Chemical Physics (2001), 272

The threshold photoelectron spectroscopic (TPES) and the photoionization mass spectrometric (PIMS) study of Methyl Chloride (CH3Cl) in the 8-20 eV photon energy is presented. The interpretation and ... [more ▼]

The threshold photoelectron spectroscopic (TPES) and the photoionization mass spectrometric (PIMS) study of Methyl Chloride (CH3Cl) in the 8-20 eV photon energy is presented. The interpretation and assignments are supported by ab initio calculations. The detailed analysis of the TPES shows numerous features in the Jahn-Teller split ground X2E(2A'-2A") state of CH3Cl+ and a new continuus band peaking at 13.4 eV. These were assigned to both direct ionization and autoionizing transitions. The transitions to the A2A1 and to the B2E states undergo a large enhancement ascribed to important autoionizing contributions. Based on the present calculations, the weak to very weak signals in the 19-26 eV photon energy range were mainly assigned to 2a1-1 ionization and to double excitations described essentially by 2e-2, 4a11 and 1e-1, 2e-1, 4a11 configurations. The PIMS study allowed us to investigate in detail the ionization and dissociation of CH3Cl+ into CH2+, CH3+, CHCl+ and CH2Cl+ from threshold up to 20 eV photon energy. At the onset, the CH3+, CHCl+ and CH2Cl+ fragment ion production is correlated to the ground state of CH3Cl+ and all fragment ions have to appear through dissociative autoionization from the 2e->3p Rydberg state. This interpretation is supported by the photoabsorption spectrum (PAS) measured recently in the same photon energy range. At higher energies, beside direct dissociation of the A2A1 and B2E states of CH3Cl+ autoionization also contributes to the fragmentation in all decay channels. For CH3+ the photoion-pair process is analyzed and detailed assignments are proposed on the basis of recent PAS data. [less ▲]

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See detailSize-related predation reduces intramorph competition in paedomorphic Alpine newts
Denoël, Mathieu ULg; Joly, Pierre

in Canadian Journal of Zoology (2001), 79(6), 943-948

Evolutionary theory assumes that facultative paedomorphosis in newts and salamanders is adaptive in allowing either a younger age at maturity or resource partitioning between the heterochronic morphs. In ... [more ▼]

Evolutionary theory assumes that facultative paedomorphosis in newts and salamanders is adaptive in allowing either a younger age at maturity or resource partitioning between the heterochronic morphs. In newt populations that only take the metamorphic ontogenetic pathway, juveniles are terrestrial and avoid food competition with larvae and breeding adults. In contrast, in populations where paedomorphosis occurs, branchiate newts of all sizes coexist in the aquatic habitats, posing the question of whether intramorph competition exists and its relationship with the evolution of paedomorphosis. We studied size-related predation in such a size-structured community of branchiate Alpine newts (Triturus alpestris) inhabiting a deep alpine lake. Although gape limitation may explain such size-related predation, individuals also exhibited selectivity according to prey size. Amongst small prey that were within the capture range of all newt size classes, smaller newts preyed on smaller items than did larger ones. We assume that such decisions favour the coexistence of different-sized individuals. It is suspected that such size-selective predation on items which are avoided by water-living metamorphs allows the maintenance of facultative paedomorphosis, in favouring resource partitioning between morphs. [less ▲]

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See detailB2 agonists cross the bovine placenta
Boutet, Philippe ULg; Uysterpruyst, C. H.; Degand, Guy ULg et al

in Pflügers Archiv : European Journal of Physiology (2001), 442(R41),

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See detailCompact holographic camera based on photorefractive crystals and application in interferometry
Georges, Marc ULg; Scauflaire, Véronique; Lemaire, Philippe

in Optical Materials (2001), 18

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See detailLes souches pathogènes d'Escherichia coli chez les chiens et les chats: III) Données bactériologiques et cliniques sur les souches nécrotoxinogènes et sur celles positives pour des adhésines
Mainil, Jacques ULg; Wilbaux, Myriam; Jacquemin, Etienne et al

in Annales de Médecine Vétérinaire (2001), 145(6), 343-354

The purpose of this study was to characterize 25 necrotoxigenic Escherichia coli type 1 (NTEC1), one necrotoxigenic E coli type 2 (NTEC2) and 16 non-necrotoxigenic E coli isolated, between 1979 and 1993 ... [more ▼]

The purpose of this study was to characterize 25 necrotoxigenic Escherichia coli type 1 (NTEC1), one necrotoxigenic E coli type 2 (NTEC2) and 16 non-necrotoxigenic E coli isolated, between 1979 and 1993, from feces, intestinal content or internal organs of dogs and cats using a uniform and standardized typing scheme, as previously described on NTEC1 and NTEC2 isolates from cattle, humans and pigs (Mainil et al, 1999). The results obtained by colony hybridization and PCR on the NTEC1 isolates were homogeneous: eighteen NTEC1 isolates harboured prs- and sfa/foc-related DNA sequences; five NTEC1 isolates harboured sfa/foc-related DNA sequences; one NTEC1 isolate harboured prs-related DNA sequences; and one was negative. The only NTEC2 isolate was also negative. Only a few NTEC1 isolates were positive for f17-, afa- or cdt-related DNA sequences. All NTEC1 and the NTEC2 isolates were haemolytic on blood agar and were resistant to the bactericidal activity of the serum (one exception). By contrast a very few produced an aerobactin or a colicin. The strains belonged to various serogroups and many could not be identified with the immunsera used. On the other hand all but one NTEC1 isolates belonged to biotype 9. The most typical profile identifed for NTEC1 from dogs and cats was: CNF1+Prs+S+Hly+Bio9+. The results obtained on the non-necrotoxigenic E. coli isolates were more heterogeneous: two of them harboured pap/prs- and sfa/foc-related DNA sequences; ten harboured pap/prs-related DNA sequences; and four, other DNA sequences. The results of the phenotypic assays were more heterogeneous also. NTEC1 strains were isolated from essentially young puppies and kitties (< 3 months for 16 out of 22), with sometimes older animals (up to 12 years). The digestive pathologies were non haemorrhagic diarrhea/enteritis essentially. When haemorrhagic diarrhea/enteritis were observed, other infectious agents were present or strongly suspected (parvovirus, Salmonella). Extraintestinal pathologies were septicaemic or systemic colibacillosis, with one case of necro-haemorrhagic metritis. NTEC1 and non-NTEC were not frequently antibiotic resistant. The most frequent resistant were to ampicillin, trimethoprim/sulfonamides and neomycin. [less ▲]

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