References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailCD34+ cell dose predicts costs after autologous peripheral blood stem cell transplantation for breast cancer.
Baron, Frédéric ULg; Copizza, Sandra; Baudoux, Etienne ULg et al

in Haematologica (2004), 89(9), 1146-8

We assessed the effect of CD34+ cell dose on costs in breast cancer patients undergoing autologous peripheral blood stem cell (PBSC) transplantation. Mean hospitalization costs were 26,992.9+/-9582.9 for ... [more ▼]

We assessed the effect of CD34+ cell dose on costs in breast cancer patients undergoing autologous peripheral blood stem cell (PBSC) transplantation. Mean hospitalization costs were 26,992.9+/-9582.9 for patients receiving a CD34+ cell dose <5 x 10(6) cells/kg versus 22,339.4+/- 5471.1 for those receiving >5 x 10(6) CD34+ cells/kg (p=0.0065). [less ▲]

Detailed reference viewed: 36 (7 ULg)
Full Text
Peer Reviewed
See detailPerspectives nouvelles dans le traitement de l’éjaculation précoce
Kempeneers, Philippe ULg; Bauwens, Sabrina; De Sutter, Pascal

in Revue Francophone de Clinique Comportementale et Cognitive (2004), 9(4), 1-8

At the moment, the scientific community recognizes two main treatments of premature ejaculation: (1) the “classical” method elaborated by Masters and Johnson in 1970 and (2) a pharmacological method ... [more ▼]

At the moment, the scientific community recognizes two main treatments of premature ejaculation: (1) the “classical” method elaborated by Masters and Johnson in 1970 and (2) a pharmacological method consisting in using antidepressant drugs, mostly those with a serotoninergic action. Although they are both relatively effective, these methods also have their drawbacks: uncertain theoretical basis, frequently unsuitable application, need for partner’s collaboration, a certain lack of eroticism and frequent relapses for the classical method; strictly symptomatic action and side effects for the pharmacological method. A synthesis of several works throws new light on the causes of premature ejaculation and offers thus a theoretical justification to a set of original therapeutic techniques elaborated by De Carufel (1996) and Desjardins (1985). The particularity of these techniques is that they stress the importance of regulating the sexual arousal in order to increase the ejaculatory latency and to promote a specific behaviour in order to achieve this goal during coitus. Clinical studies conducted over the past few years show that treatments including these techniques are at least as effective as the classical method and are probably able to overcome some of its drawbacks: the regulation techniques seem clearer from a theoretical point of view, easier to apply and more able to work without the partner’s collaboration. [less ▲]

Detailed reference viewed: 272 (8 ULg)
Full Text
Peer Reviewed
See detailLes modes alternatifs de règlement des différends: anges ou démons?
Caprasse, Olivier ULg

in Revue de la Faculté de Droit de l'Université de Liège (2004)

Detailed reference viewed: 34 (3 ULg)
Full Text
Peer Reviewed
See detailEtching techniques for realizing optical micro-cavity atom traps on silicon
Moktadir, Zakaria; Koukharenka, Elena; Kraft, Michaël ULg et al

in Journal of Micromechanics and Microengineering (2004), 14(9), 82-85

We have fabricated curved optical micromirrors on silicon. We expect to be able to form open optical cavities between these mirrors and plane mirrors coated on the ends of optical fibres. The curved mirror ... [more ▼]

We have fabricated curved optical micromirrors on silicon. We expect to be able to form open optical cavities between these mirrors and plane mirrors coated on the ends of optical fibres. The curved mirror templates have been prepared with less than 10 nm surface roughness by means of isotropic chemical etching. Two different methods are used for the fabrication of the mirrors: the first method uses a silicon oxide mask, while the second uses dry etching to form an indentation in the silicon surface that is opened out by wet isotropic etching. After coating the silicon substrate with gold, good quality mirrors are obtained with R ∼ 98% in the near infra-red. We find that a reflectivity of approximately 98% can be achieved by this method. Cavities formed from these mirrors will be useful for manipulating single atoms. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailInfluence of the operating conditions on the production rate of multi-walled carbon nanotubes in a CVD reactor
Gommes, Cédric ULg; Blacher, Silvia ULg; Bossuot, C. et al

in Carbon (2004), 42(8-9), 1473-1482

A kinetic study is presented for the synthesis of multi-walled carbon nanotubes in a semi-continuous chemical vapor deposition reactor. The study is based on the use of a mass spectrometer that allows the ... [more ▼]

A kinetic study is presented for the synthesis of multi-walled carbon nanotubes in a semi-continuous chemical vapor deposition reactor. The study is based on the use of a mass spectrometer that allows the reaction rate to be inferred from the exhaust gas composition measurements. The tested reactor operating variables are the length and thickness of the catalytic bed, the total feed flow and the molar fraction of hydrocarbon in the feed. The results of the study are analyzed using well known reactor engineering models, which allows the origin of the observed physical limitations to be ascertained. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 71 (20 ULg)
Full Text
Peer Reviewed
See detailLe voyage en Terre Sainte de Barthélemy des Champs, récollet et pèlerin liégeois (1666-1667)
Dury, Julie ULg

in Bulletin de la Société d'Art et d'Histoire du Diocèse de Liège (2004), LXVI

Detailed reference viewed: 25 (3 ULg)
Full Text
Peer Reviewed
See detailEvaluation of three serum i-ELISA's using monoclonal antibodies and protein G as peroxidase conjugate for the diagnosis of bovine brucellosis
Saegerman, Claude ULg; De Waele, L.; Gilson, D. et al

in Veterinary Microbiology (2004), 100

Three i-ELISAs using LPS, the immunodominant component of Brucella abortus, were developed with three different conjugates: monoclonal antibodies 1C8 (anti-bovine IgG(1)) and 3H3 (mainly specific for ... [more ▼]

Three i-ELISAs using LPS, the immunodominant component of Brucella abortus, were developed with three different conjugates: monoclonal antibodies 1C8 (anti-bovine IgG(1)) and 3H3 (mainly specific for bovine IgG(2) but also reacting with IgG(1)) and protein G (reacts with both bovine IgG subclasses). Using a cut-off value of 2.5U/ml, the i-ELISA with 3H3 as conjugate had a specificity (95% CI: 98.32-99.63%) that was significantly higher than the same assay with 1C8 (95% CI: 96.08-98.26%) or PG (95% CI: 95.83-98.09%). In areas where false positive serological reactions (FPSR) were common, the specificity of the i-ELISAs decreased significantly. The specificity of the i-ELISAs increased with the age of the animals tested, irrespective of the conjugate. The specificity of the i-ELISAs and traditional tests was also examined using sera from animals infected per os with bacteria bearing LPS similar to the Brucella LPS. It appeared that Yersinia enterocolitica O:9, Xanthomonas maltophilia and Salmonella urbana infections induced FPSR both in the i-ELISAs and in the traditional tests, but the 3H3 assay was significantly less prone to produce false positive reactions than the 1C8 and PG assays. The i-ELISAs were more sensitive, allowed earlier detection, and were more persistent than the traditional serological tests both in experimentally and naturally Brucella-infected animals. Weekly i-ELISA monitoring of experimentally infected pregnant heifers (previously vaccinated or not) allowed a prediction of abortion. Furthermore, the 1C8 assay showed significantly higher titres irrespective of day post-infection and vaccination status. The accuracy of the assay could be improved by making use of additional information (e.g. animal age or conjugate) and by selecting appropriate cut-off points on the basis of the prevailing epidemiological situation. The i-ELISAs appear an appropriate choice in order to maintain an official brucellosis-free status because of their sensitivity, early detection and long persistence and, for the same reasons, seem especially valuable for the detection of latent carriers (i.e. animals classified negative by classical serological tests) among imported [less ▲]

Detailed reference viewed: 38 (8 ULg)
Full Text
Peer Reviewed
See detailFrontières en Afrique centrale : gage de souveraineté ?
Kabamba, Bob ULg

in Fédéralisme - Régionalisme (2004), volume 4

Detailed reference viewed: 24 (3 ULg)
Full Text
Peer Reviewed
See detailInsight and the sleep committee
Maquet, Pierre ULg; Ruby, Perrine

in Nature (2004), 427(6972), 304-305

We all spend about a third of our lives asleep, an essential but seemingly unproductive state. Experimental evidence now emerges to support anecdotal evidence that sleep can stimulate creative thinking.

Detailed reference viewed: 57 (11 ULg)
Full Text
Peer Reviewed
See detailReport on two lichenological field meetings in the province of Luxembourg in Belgium
Diederich, Paul; Van den Broeck, Dries; Ertz, Damien et al

in Bulletin de la Société des Naturalistes Luxembourgeois (2004), 105

Detailed reference viewed: 9 (0 ULg)
See detailL'intervention psychologique auprès des victimes : questions éthiques
Mormont, Christian ULg

in Courrier de l'Ethique Médicale (2004), 4(1), 24-25

Detailed reference viewed: 37 (1 ULg)
Full Text
Peer Reviewed
See detailDynamique de la filière viande de brousse dans la partie continentale du Rio Muni en Guinée équatoriale
Njikam Nsangou, Ibrahim ULg

in Tropicultura (2004), 22(4), 204-210

The aim of this study was to do surveys about bush meat networks around urban centers near the Monte Alen National Park in Equatorial Guinea. During 8 weeks, in the Mundoasi market, one of two principal ... [more ▼]

The aim of this study was to do surveys about bush meat networks around urban centers near the Monte Alen National Park in Equatorial Guinea. During 8 weeks, in the Mundoasi market, one of two principal market of Bata, 4328 wild animal carcases have been indexed, representating 22,600 kg of biomass. A total of 48 animals species have been identified, including 14 which hunting are prohibited. The mammals represent 91.87% of total number with 3 dominants orders, ungulates (37.7%), primates (28.6%) and rodents (18%). The duiker (Cephalophus), the African Brushtailed Porcupine and Guenon are the most important. The district of Niefang, Bata and Evinayong are the principal sources of supply. Hunting with gun becomes very important, follow by snaring, a very wasteful method. Despite that this business squarely growth, signs of wildlife decrease are perceptible, showing evidence of overexploitation. As far as Monte Alen National Park is concerned, this study shows the positive effects of this protected area as wildlife reservoir for peripheral hunting zones. [less ▲]

Detailed reference viewed: 49 (7 ULg)
Full Text
See detailLes liens entre attention et mémoire à court terme verbale
Poncelet, Martine ULg; Majerus, Steve ULg

in Rééducation Orthophonique (2004), 218

Detailed reference viewed: 67 (26 ULg)
Full Text
Peer Reviewed
See detailLe systeme de prepaiement au Rwanda (II): adhesion et utilisation des services par les beneficiaires.
Musango, Laurent; Martiny, Patrick; Porignon, Denis ULg et al

in Sante (Montrouge, France) (2004), 14(2), 101-7

In Rwanda, the Ministry of Health is rebuilding the health sector destroyed during the genocide while trying to guarantee the financial accessibility of the population to the services through the setting ... [more ▼]

In Rwanda, the Ministry of Health is rebuilding the health sector destroyed during the genocide while trying to guarantee the financial accessibility of the population to the services through the setting up of a prepayment scheme. Membership remains low in the three pilot districts where the prepayment scheme was introduced four years before (15,6%). In two of these districts, the curative consultation and maternity utilisation has increased appreciably. The members of the prepayment scheme make greater use of the services than the rest of the population. There is a significantly higher prepayment scheme membership among households with a relatively high income and those with a large family (more than 5 family members). Overall, non-members of the prepayment scheme spend more on health services than members do. There are indications that developing the prepayment scheme would be very useful for the people in Rwanda if specific strategies geared to the poor were set up. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailAnalysis of experimental conditions for simultaneous measurements of transport and magnetotransport coefficients of high temperature superconductors
Mucha, J.; Dorbolo, Stéphane ULg; Bougrine, Hassan ULg et al

in Cryogenics (2004), 44(3), 145-149

Experimental conditions for simultaneous measurements of transport coefficients of high temperature superconductors in zero and non-zero magnetic fields are analysed. Test measurements of the thermal ... [more ▼]

Experimental conditions for simultaneous measurements of transport coefficients of high temperature superconductors in zero and non-zero magnetic fields are analysed. Test measurements of the thermal conductivity, the thermoelectric power and the Nernst-Ettingshausen effect of a textured Bi2212 sample are reported in an external magnetic field of 2 T. Errors related to parameters of the thermocouple used and to the spurious heat flows are discussed for a new experimental set-up built based on a closed cycle helium refrigerator. Possible optimising of experimental conditions is suggested. (C) 2003 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 34 (7 ULg)
Full Text
Peer Reviewed
See detailEpithelial metaplasia: an inadequate environment for antitumour immunity?
Delvenne, Philippe ULg; Hubert, Pascale ULg; Jacobs, Nathalie ULg

in Trends in Immunology (2004), 25(4), 169-73

Detailed reference viewed: 26 (3 ULg)
Full Text
Peer Reviewed
See detailReduced proviral loads during primo-infection of sheep by Bovine Leukemia virus attenuated mutants.
Debacq, Christophe; Sanchez Alcaraz, Maria Teresa; Mortreux, Franck et al

in Retrovirology (2004), 1(1),

Detailed reference viewed: 16 (2 ULg)
Full Text
Peer Reviewed
See detailControl of vesicle fusion by a tyrosine phosphatase.
Huynh, Huong; Bottini, Nunzio; Williams, Scott et al

in Nature cell biology (2004), 6(9), 831-9

The tyrosine phosphatase PTP-MEG2 is targeted by its amino-terminal Sec14p homology domain to the membrane of secretory vesicles. There it regulates vesicle size by promoting homotypic vesicle fusion by a ... [more ▼]

The tyrosine phosphatase PTP-MEG2 is targeted by its amino-terminal Sec14p homology domain to the membrane of secretory vesicles. There it regulates vesicle size by promoting homotypic vesicle fusion by a mechanism that requires its catalytic activity. Here, we identify N-ethylmaleimide-sensitive factor (NSF), a key regulator of vesicle fusion, as a substrate for PTP-MEG2. PTP-MEG2 reduced the phosphotyrosine content of NSF and co-localized with NSF and syntaxin 6 in intact cells. Furthermore, endogenous PTP-MEG2 co-immunoprecipitated with endogenous NSF. Phosphorylation of NSF at Tyr 83, as well as an acidic substitution at the same site, increased its ATPase activity and prevented alphaSNAP binding. Conversely, expression of a Y83F mutant of NSF caused spontaneous fusion events. Our results suggest that the molecular mechanism by which PTP-MEG2 promotes secretory vesicle fusion involves the local release of NSF from a tyrosine-phosphorylated, inactive state. This represents a novel mechanism for localized regulation of NSF and the first demonstrated role for a protein tyrosine phosphatase in the regulated secretory pathway. [less ▲]

Detailed reference viewed: 58 (0 ULg)
Full Text
Peer Reviewed
See detailAntimicrobial potential of probiotic or potentially probiotic lactic acid bacteria, the first results of the international European research project PROPATH of the PROEUHEALTH cluster
De Vuyst, L.; Lefteris, M.; Lazlo, A. et al

in Microbial Ecology in Health & Disease (2004), 16

The EU-funded PROPATH project addresses the important health issue of prevention of gastrointestinal disorders through probiotics and prebiotics. Seven European laboratories are co-operating in this ... [more ▼]

The EU-funded PROPATH project addresses the important health issue of prevention of gastrointestinal disorders through probiotics and prebiotics. Seven European laboratories are co-operating in this project, which aims to isolate and characterize the relevant antimicrobial agents to combat Gram-negative bacteria including Helicobacter pylori and Salmonella enterica serovar Typhimurium. In this paper, the first results on the screening for probiotic or potentially probiotic lactobacilli that exhibit antimicrobial activity towards these Gram-negative pathogenic bacteria are presented. Spot-on-lawn assays, well-diffusion assays and time-kill studies were performed among the lactic acid bacteria strains that were either collected from fermented foods and faeces (breast-fed babies, infants and animals) or isolated from commercial products to investigate whether any of the collected strains were inhibiting growth of or were killing certain indicator bacteria. Strains inhibiting the gastrointestinal pathogens mentioned above were found. Evidence has been obtained that compounds different from organic acids are produced. [less ▲]

Detailed reference viewed: 206 (2 ULg)
Full Text
Peer Reviewed
See detailDes nombres qui modélisent des transformations.
Rosseel; Schneider, Marguerite ULg

in Petit X (2004), 64

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailInfluence of the capillary temperature and the source pressure on the internal energy distribution of electrosprayed ions
Gabelica, Valérie ULg; De Pauw, Edwin ULg; Karas, Michael

in International Journal of Mass Spectrometry (2004), 231(2-3), 189-195

The internal energy distributions in a heated capillary nano-electrospray source have been determined using the "survival yield" method. At low capillary temperatures, the internal energy distribution is ... [more ▼]

The internal energy distributions in a heated capillary nano-electrospray source have been determined using the "survival yield" method. At low capillary temperatures, the internal energy distribution is characterized by a low-energy tail, which can be attributed to a fraction of ions not fully desolvated in the heated capillary. This low-energy tais is shown to disappear when the source pressure is increased. This explains why increased source pressure is favorable in the case of highly hydrophilic compounds or non-covalent complexes in order to achieve sufficient desolvation without fragmentation. It is also shown that "high temperature-low voltage" are not equivalent to "low temperature-high voltage" source conditions. These observations are important for fundamental issues as well as for source-CID mass spectral library searching applications. [less ▲]

Detailed reference viewed: 56 (1 ULg)
Full Text
Peer Reviewed
See detailImpact of hydroelectric power releases on the morphology and the sedimentology of the bed of the Warche River (Belgium).
Assani, A. A.; Petit, François ULg

in Earth Surface Processes & Landforms (2004)

Detailed reference viewed: 69 (21 ULg)
Full Text
Peer Reviewed
See detailA Parasite Reveals Cryptic Phylogeographic History of Its Host: The Colonization of the Western Mediterranean Islands
Nieberding, Caroline; Morand, Serge; Libois, R. et al

in Multidisciplinarity for Parasites, Vectors and Parasitic Diseases (2004), 1

Detailed reference viewed: 11 (0 ULg)
Full Text
See detailBiocénose cutanée, peptides antimicrobiens cutanés et antiseptiques.
Flagothier, Caroline ULg; Uhoda, Emmanuelle ULg; Goffin, Véronique ULg et al

in Dermatologie Actualité (2004), 86

Detailed reference viewed: 30 (0 ULg)
Full Text
Peer Reviewed
See detailHaematopoetic stem cell transplantation for refractory autoimmune cytopenia.
Passweg, J. R.; Rabusin, M.; Musso, M. et al

in British Journal of Haematology (2004), 125(6), 749-55

This study describes the outcome of patients receiving haematopoietic stem cell transplantation (HSCT) to treat severe refractory autoimmune cytopenia. The registry of the European Group of Blood and ... [more ▼]

This study describes the outcome of patients receiving haematopoietic stem cell transplantation (HSCT) to treat severe refractory autoimmune cytopenia. The registry of the European Group of Blood and Marrow Transplantation holds data on 36 patients receiving 38 transplants, the first transplant was autologous for 27 and allogeneic for nine patients. Patients had autoimmune haemolytic anaemia (autologous: 5; allogeneic: 2), Evans's syndrome (autologous: 2; allogeneic: 5); immune thrombocytopenia (autologous: 12), pure red cell aplasia (autologous: 4; allogeneic: 1), pure white cell aplasia (autologous: 1; allogeneic 1), or thrombotic thrombocytopenic purpura (autologous: 3). Patients had longstanding disease having failed multiple prior treatments. Among 26 evaluable patients mobilized for autologous HSCT, three died of treatment-related causes, one died of disease progression, seven were non-responders, six patients had transient responses and nine had continuous partial or complete remission. Of the seven evaluable patients receiving allogeneic HSCT, one died of treatment-related complications, one with transient response died of progressive disease and five had a continuous response. Autologous and allogeneic HSCT may induce a response in a subset of patients with autoimmune cytopenia of long duration albeit at the price of considerable toxicity. [less ▲]

Detailed reference viewed: 52 (11 ULg)
Full Text
See detailParavion : Hafid Bouazza tussen het particuliere en het universele
Spinoy, Erik ULg

in Nieuwzuid (2004), 4(14), 4-14

This article is a reading of the novel Paravion by the Dutch-Moroccon novelist, focusing on the tension between the universal and the particular this novel bears witness to.

Detailed reference viewed: 140 (9 ULg)
Full Text
Peer Reviewed
See detailComment j'explore ... les dermites des langes.
Flagothier, Caroline ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2004), 59(2), 106-9

Diaper dermatitis is a frequent condition. Several clinical types are distinguished. The most frequent type results from increased fragility of the newborn buttock skin when covered by diapers. According ... [more ▼]

Diaper dermatitis is a frequent condition. Several clinical types are distinguished. The most frequent type results from increased fragility of the newborn buttock skin when covered by diapers. According to the mechanisms involved and the severity of the dermatitis, one can distinguish the intertrigo of the chubby baby, and the so-called "W", "Y" and "red panties" types of diaper dermatitis. When the effects of occlusion are not controlled by adequate absorption by the diapers, hyperhydration of the stratum corneum occurs and progresses to maceration. As a result, the value of the coefficient of friction of the skin increases with epidermal weakening to rubbing. In addition, fecal enzymes (urease, proteases and lipases) alter urines and skin. Judicious hygiene measures and the correct choice of diapers are mandatory. Cutaneous colonization by microorganisms, the most important of which being Candida albicans, is the main complication. Adequate preventive and curative measures can combat diaper dermatitis with confidence. A miconazole paste allows to improve the tribological properties of the interface between diapers and the skin. It also abates the impact of Candida albicans in the pathogenesis of the skin disorder. [less ▲]

Detailed reference viewed: 116 (0 ULg)
Full Text
Peer Reviewed
See detailEEMCO guidance for the assessment of hair shedding and alopecia.
Pierard, Gérald ULg; Pierard, Claudine ULg; Marks, R. et al

in Skin Pharmacology & Physiology (2004), 17(2), 98-110

Knowledge of the hair follicle anatomy and the dynamics of hair cycling is substantial. Recognizing the anagen, catagen and telogen phases as well as teloptosis and the hair eclipse phenomenon clearly ... [more ▼]

Knowledge of the hair follicle anatomy and the dynamics of hair cycling is substantial. Recognizing the anagen, catagen and telogen phases as well as teloptosis and the hair eclipse phenomenon clearly characterizes the typical hair chronobiology. Physiological modulators include hormones, neuromediators, miscellaneous biomolecules, seasons, micro-inflammation and ageing. For individuals who present with the complaint of increased hair shedding or alopecia, a host of evaluation techniques are available in addition to history, physical examination and laboratory assessment. Various clinical hair techniques can help in assessing the efficacy of drugs and cosmetics on hair growth. The methods are quite similar to those used to establish a definite diagnosis in dermatological practice. Great strides have been made during the recent decades in the methodology of hair growth trials in dermatology and cosmetology. Clinical evaluations benefit from a few additional specific techniques that enhance the perception of hair (re-) growth, shedding and alopecia. These assessments include the determination of hair patterning and density that may be helped by the 'black-and-white felt' examination. Daily hair counts, the 'hair pull test' and the 'hair feathering test' are also available. Instrumental methods provide reliable quantitative information that is useful if there are adequate controls. Some photographic methods, the trichogram, hair weighing and variants of the hair growth window technique including the phototrichogram, videotrichogram and tractio-phototrichogram provide insight into the complexities of hair cycling and shedding. Skin biopsy is indicated for diagnostic purposes, especially when the hair loss is accompanied by scarring. [less ▲]

Detailed reference viewed: 68 (0 ULg)
Full Text
Peer Reviewed
See detailBeaux vieux mots de Braine-le-Comte (Belgique)
Droixhe, Daniel ULg

in Linguistique picarde (2004), 44(170), 1-13

Detailed reference viewed: 72 (5 ULg)
Full Text
Peer Reviewed
See detailDeux chansons wallonnes sur la translation des reliques de sainte Alénie à Liège en 1843
Droixhe, Daniel ULg

in Bulletin de la Société Royale Le Vieux-Liège (2004), XIV(304), 502-508

Detailed reference viewed: 150 (11 ULg)
Full Text
Peer Reviewed
See detailInvisible Sketch Interface in Architectural Engineering, in Graphics Recognition, Recent Advanced and Perspectives
Leclercq, Pierre ULg

in Lecture Notes in Computer Science (2004), 3088

Detailed reference viewed: 35 (8 ULg)
Full Text
Peer Reviewed
See detailAlignment of glial cells stimulates directional neurite growth of cns neurons in vitro
Deumens, R.; Koopmans, G. C.; Den Bakker, C. G. J. et al

in Neuroscience (2004), 125(3), 591-604

Olfactory ensheathing cells (OECs) together with olfactory nerve fibroblasts (ONFs) and neonatal astrocytes are potent stimulators of neurite growth in adulthood and during development, respectively ... [more ▼]

Olfactory ensheathing cells (OECs) together with olfactory nerve fibroblasts (ONFs) and neonatal astrocytes are potent stimulators of neurite growth in adulthood and during development, respectively. Since it is known that alignment of glial cells is important for the correct outgrowth of axon tracts, it was hypothesized that the alignment of glial cells stimulates directional and enhanced neurite outgrowth. Adult OEC/ONF and neonatal astrocytes were cultured either on biodegradable poly(D,L)-lactide matrices or in Petri dishes for 4 days. Thereafter neonatal cerebral cortical neurons were added. After a 2-days coculture period the cultures were fixed and processed for a combined MAP-2 and phosphorylated neurofilament (RT97) staining. The neurite growth (neurite elongation and neurite formation) and the neurite direction were assessed. We show that (1) OEC/ONF cultures are more potent in stimulating the length of the longest neurite of cocultured neurons, (2) alignment of glial is achieved in vitro on our biomatrices, (3) aligned glial/biomatrix complexes do not enhance neurite growth, and (4) aligned glial/biomatrix complexes direct neurite outgrowth. These data have significant implications for in vivo experiments focusing on glial transplantation. Transplanting glial/biomatrix complexes may stimulate the directional regrowth of severed axons across a lesion site. (C) 2004 IBRO. Published by Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 47 (2 ULg)
Full Text
Peer Reviewed
See detailForest and garden: traces of wildness in a modernizing land, 1897-1949 (M.L. Simo).
Bogaert, Jan ULg

in Landscape Journal (2004), 23(2), 174-176

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailThe contribution of 211 particles to the mechanical reinforcement mechanism of 123 superconducting single domains
Mathieu, Jean-Philippe; Cano, I. G.; Koutzarova, T. et al

in Superconductor Science and Technology (2004), 17(1), 169-174

Hardness and fracture toughness of Dy-123 single domains were studied by Vickers in micro-indentation. A significant anisotropy of the mechanical properties was observed. Hardness tests give higher values ... [more ▼]

Hardness and fracture toughness of Dy-123 single domains were studied by Vickers in micro-indentation. A significant anisotropy of the mechanical properties was observed. Hardness tests give higher values when performed in (001) planes rather than in planes parallel to the c-axis. Moreover, the cracks pattern around the indentation follows preferential orientation in planes parallel to the c-axis whereas a classical 'four-cracks' pattern is observed in the (001) planes. It has been possible to show the crucial role played by the 211 particles in the deviating mechanism of cracks and the relevance of the high homogeneity of 211-particle distribution in the material. [less ▲]

Detailed reference viewed: 48 (9 ULg)
Full Text
Peer Reviewed
See detailEtiologies et exploration electrophysiologique des paralysies diaphragmatiques.
MAERTENS DE NOORDHOUT, Alain ULg

in Revue Neurologique (2004), 160(12), 1239-44

Detailed reference viewed: 5 (0 ULg)
Full Text
See detailLes dispositifs transdermiques et la fonction barrière cutanée.
Uhoda, Emmanuelle ULg; Salomon Neira, Martin; Pierard, Gérald ULg

in Skin (2004), 7

La couche cornée, exerce une remarquable fonction barrière limitant à la fois la perte d’eau et d’électrolytes par la peau et la pénétration de xénobiotiques dans l'organisme. Les dispositifs ... [more ▼]

La couche cornée, exerce une remarquable fonction barrière limitant à la fois la perte d’eau et d’électrolytes par la peau et la pénétration de xénobiotiques dans l'organisme. Les dispositifs transdermiques cherchent à contourner cette propriété afin de forcer le passage d’une quantité contrôlée de substances pharmacologiquement actives au travers de la peau. Le but est de transférer par la microvascularisation cutanée la substance souhaitée, tout en évitant les aléas tant de la dégradation et l'absorption irrégulière par le tractus digestif que de la métabolisation au cours du premier passage hépatique. Cette méthode est indiquée pour un nombre limité de principes actifs puissants ayant une biodisponibilité orale faible ou courte. La sonophorèse et l'iontophorèse sont deux autres méthodes recherchant le même but. [less ▲]

Detailed reference viewed: 105 (0 ULg)
Full Text
Peer Reviewed
See detailEthnocentrism, Nationalism and Post-Nationalism in the Tales of Subcomandante Marcos
Vanden Berghe, Kristine ULg

in Mexican Studies (2004), 20(1), 123-144

A discourse analysis shows that the literary passages in subcomandante Marcos’ press releases (Relatos de el viejo Antonio, Chiapas, CIACH, 1998 and Don Durito de la Lacandona, Chiapas, CIACH, 1999 ... [more ▼]

A discourse analysis shows that the literary passages in subcomandante Marcos’ press releases (Relatos de el viejo Antonio, Chiapas, CIACH, 1998 and Don Durito de la Lacandona, Chiapas, CIACH, 1999) express both the ethnical, national and post-national demands of the EZLN. The analysis reveals three tensions in the discourse, which seem to reflect the divergent pressures on the EZLN. [less ▲]

Detailed reference viewed: 96 (3 ULg)
Full Text
Peer Reviewed
See detailRenin-angiotensin system inhibition prevents type 2 diabetes mellitus. Part 2. Overview of physiological and biochemical mechanisms.
Scheen, André ULg

in Diabètes & Métabolism (2004), 30(6), 498-505

The inhibition of the renin-angiotensin system (RAS) with either angiotensin converting enzyme inhibitors (ACEIs) or AT1 angiotensin receptor blockers (ARBs) consistently and significantly reduces the ... [more ▼]

The inhibition of the renin-angiotensin system (RAS) with either angiotensin converting enzyme inhibitors (ACEIs) or AT1 angiotensin receptor blockers (ARBs) consistently and significantly reduces the incidence of type 2 diabetes in patients with hypertension or congestive heart failure. The mechanisms underlying this protective effect appear to be complex and may involve an improvement of both insulin sensitivity and insulin secretion. These two effects may result, at least in part, from the well known effects of these pharmacological agents on the vascular system on the one hand, on the ionic balance on the other hand. Indeed, the vasodilation induced by ACEIs or ARBs could improve the blood circulation in skeletal muscles, thus favouring peripheral insulin action, but also in the pancreas, thus promoting insulin secretion. Preserving cellular potassium and magnesium pools by blocking the aldosterone effects could also improve both cellular insulin action and insulin secretion. However, besides these classical effects, new mechanisms have been recently suggested. A direct effect of the inhibition of angiotensin and/or of the enhancement of bradykinin on various steps of the insulin cascade signalling has been described as well an increase in GLUT4 glucose transporters after RAS inhibition. Furthermore, it has been demonstrated that angiotensin II inhibits adipogenic differentiation of human adipocytes via A1 receptors and, therefore, it has been hypothesised that RAS blockade may prevent diabetes by promoting the recruitment and differentiation of adipocytes. Finally, some lipophilic ARBs appear to induce PPAR-gamma activity in the adipose tissue. Hence, the protection against type 2 diabetes observed after RAS inhibition may be partially linked to a thiazolidinedione-like effect. In conclusion, numerous physiological and biochemical mechanisms could explain the protective effect of RAS inhibition against the development of type 2 diabetes in individuals with arterial hypertension or congestive heart failure. What might be the main mechanism in the overall protection effect of ACEIs or ARBs remains an open question. [less ▲]

Detailed reference viewed: 40 (3 ULg)
Full Text
Peer Reviewed
See detailMolecule orientation in self-assembled monolayers determined by infrared-visible sum-frequency generation spectroscopy
Mani, A. A.; Schultz, Z. D.; Champagne, B. et al

in Applied Surface Science (2004), 237

The molecular orientation in self-assembled monolayers of thiophenol (TP) on Ag(1 1 1) and of para-nitroanilinododecane-thiol (NAT) on Au was investigated by infrared-visible sum-frequency generation ... [more ▼]

The molecular orientation in self-assembled monolayers of thiophenol (TP) on Ag(1 1 1) and of para-nitroanilinododecane-thiol (NAT) on Au was investigated by infrared-visible sum-frequency generation between 500 and 1500 cm-1. Ab initio calculations were performed to determine the interface nonlinear response. The combined experimental and theoretical results reveal that the S–C bond of TP is tilted 37° from the Ag(1 1 1) surface normal, with the aromatic ring plane perpendicular to the surface. On Au, the tilt angle of the NAT molecule stabilizes below 60° at the end of film growth. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailA Psammosteid Heterostracan (Vertebrata: Pteraspidomorphi) from the Emsian (Lower Devonian) of the Grand Duchy of Luxembourg
Delsate, D.; Blieck, A.; Steemans, Philippe ULg

in Geologica Belgica (2004), 7(1-2), 21-26

Detailed reference viewed: 28 (0 ULg)
Full Text
Peer Reviewed
See detailPhonological representations of children with SLI : a study of French.
Maillart, Christelle ULg; Schelstraete, Marie-Anne; Hupet, Michel

in Journal of Speech, Language, and Hearing research (2004), 47

The present research examined the quality of the phonological representations of French children with specific language impairment (SLI) and those with normal language development (NLD). Twenty-five ... [more ▼]

The present research examined the quality of the phonological representations of French children with specific language impairment (SLI) and those with normal language development (NLD). Twenty-five children with SLI and fifty normally developing children matched on lexical age level participated in an auditory lexical decision task. The observations gathered in our study can be summarized as follows. First, children with a higher receptive lexical level performed better, and this was true both for children with NLD and children with SLI. Second, both children with NLD and SLI were more likely to reject pseudo-words resulting from a modification affecting the number of syllables of a word than pseudo-words resulting from a slight modification with the number of syllables unchanged. This difference, however, was greater for the children with SLI who appeared to have much difficulty rejecting pseudo-words resulting from slight modifications. Finally, the performance of children with SLI was particularly poor when presented with pseudowords resulting from a slight modification at the beginning or the end of a word. These findings are interpreted as supporting the hypothesis of an underspecification of phonological representations in children with SLI. [less ▲]

Detailed reference viewed: 106 (10 ULg)
Full Text
Peer Reviewed
See detailFully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up.
Christians, Benoit; Fillet, Marianne ULg; Chiap, Patrice ULg et al

in Journal of Chromatography. A (2004), 1056(1-2), 105-10

A new automated method for the quantitative analysis of cyproterone acetate (CPA) in human plasma has been developed using on-line solid phase extraction (SPE) prior to the LC-MS/MS determination. The ... [more ▼]

A new automated method for the quantitative analysis of cyproterone acetate (CPA) in human plasma has been developed using on-line solid phase extraction (SPE) prior to the LC-MS/MS determination. The method was based on the use of a pre-column packed with internal-surface reversed-phase material (LiChrospher RP-4 ADS, 25 mm x 2 mm) for sample clean-up coupled to LC separation on an octadecyl silica stationary phase by means of a column switching system. A 30 microl plasma sample volume was injected directly onto the pre-column using a mixture of water, acetonitrile and formic acid (90:10:0.1 (v/v/v)) adjusted to pH 4.0 with diluted ammonia as washing liquid. The analyte was then eluted in the back-flush mode with the LC mobile phase consisting of water, methanol and formic acid (10:90:0.1 (v/v/v)). The dispensing flow rates of the washing liquid and the LC mobile phase were 300 microl min(-1). Medroxyprogesterone acetate (MPA) was used as internal standard. The MS ionization of the analytes was achieved using electrospray (ESI) in the positive ion mode. The pseudomolecular ionic species of CPA and MPA (417.4 and 387.5) were selected to generate daughter ions at 357.4 and 327.5, respectively. Finally, the developed method was validated according to a new approach using accuracy profiles as a decision tool. Very good results with respect to accuracy, detectability, repeatability, intermediate precision and selectivity were obtained. The LOQ of cyproterone acetate was 300 pg ml(-1). [less ▲]

Detailed reference viewed: 82 (2 ULg)
Full Text
Peer Reviewed
See detailSynthesis of novel D-glucuronic acid fatty esters using Candida antarctica lipase in tert-butanol
Moreau, Benoit; Lognay, Georges ULg; Blecker, Christophe ULg et al

in Biotechnology Letters (2004), 26(5), 419-424

Glucuronic acid n-alkyl esters, a novel class of promising biosurfactants and their corresponding glucose esters with the same side-chain length, were synthesized by direct esterification in a non-aqueous ... [more ▼]

Glucuronic acid n-alkyl esters, a novel class of promising biosurfactants and their corresponding glucose esters with the same side-chain length, were synthesized by direct esterification in a non-aqueous phase (tert-butanol) using an immobilized lipase. [less ▲]

Detailed reference viewed: 26 (4 ULg)
Full Text
Peer Reviewed
See detailEffect of non-steroidal anti-inflammatory drugs on amyloid-beta formation and macrophage activation after platelet phagocytosis.
Jans, Dominique ULg; Martinet, Wim; Fillet, Marianne ULg et al

in Journal of Cardiovascular Pharmacology (2004), 43(3), 462-70

Recently, we showed that platelet phagocytosis occurs in human atherosclerotic plaques and leads to foam cell formation. Platelet phagocytosis, resulting in macrophage activation and iNOS induction, was ... [more ▼]

Recently, we showed that platelet phagocytosis occurs in human atherosclerotic plaques and leads to foam cell formation. Platelet phagocytosis, resulting in macrophage activation and iNOS induction, was associated with the formation of amyloid-beta peptide (Abeta) via proteolytic cleavage of platelet-derived amyloid precursor protein (APP), possibly by secretases. To test the involvement of gamma-secretase in this process, we used indomethacin, ibuprofen, and sulindac sulfide, non-steroidal anti-inflammatory drugs (NSAIDs) known to alter the gamma-secretase cleaving site of APP, on their ability to inhibit macrophage activation evoked by platelet phagocytosis. J774 macrophages were incubated with human platelets or lipopolysaccharide (LPS) with or without NSAIDs. Nitrite was quantified as a measure for inducible nitric oxide synthase (iNOS) activity. Indomethacin, ibuprofen, sulindac sulfide, and meloxicam concentration-dependently reduced nitrite production by macrophages incubated with platelets, but did not alter LPS-induced iNOS activity or platelet uptake. However, acetylsalicylic acid and naproxen, two NSAIDs without effect on the gamma-secretase cleaving site of APP, did not affect nitrite production in either platelet- or LPS-stimulated macrophages. Surface-enhanced laser desorption/ionization time-of-flight mass-spectrometry demonstrated time-dependent formation of Abeta-containing peptides after platelet phagocytosis, which could be inhibited by indomethacin. In conclusion, these results point to the involvement of gamma-secretase in macrophage activation following platelet phagocytosis. [less ▲]

Detailed reference viewed: 25 (2 ULg)
Full Text
Peer Reviewed
See detailSelf-assembled organic and fullerene monolayers characterisation by two-colour SFG spectroscopy: a pathway to meet doubly resonant SFG process
Humbert, C.; Caudano, Y.; Dreesen, Laurent ULg et al

in Applied Surface Science (2004), 237

Two-colour sum-frequency generation (two-colour SFG) spectroscopy was used to probe both vibrational and electronic properties of 1-dodecanethiol/Ag(1 1 1), Au(1 1 1), and Pt(1 1 1), of 5-[p-(6 ... [more ▼]

Two-colour sum-frequency generation (two-colour SFG) spectroscopy was used to probe both vibrational and electronic properties of 1-dodecanethiol/Ag(1 1 1), Au(1 1 1), and Pt(1 1 1), of 5-[p-(6-mercaptohexoxy)-phenyl]-10,15,20-triphenylporphin/Pt(1 1 1), and of C60/Ag(1 1 1). The role of the various physical parameters determining the sum-frequency generation (SFG) intensity equation is highlighted. The enhancement of the non-linear second order susceptibility in the aforementioned interfaces is explained in terms of metal interband transition, molecular electronic transition and of electron–phonon coupling, respectively. [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailKritische Notizen zur Deutung des Realismus in Ingeborg Bachmanns Zikaden
Vanhaegendoren, Koen ULg

in Studi Germanici (2004), 42

Detailed reference viewed: 44 (2 ULg)
Full Text
Peer Reviewed
See detailImpact of low frequency transcranial magnetic stimulation on event-related brain potentials.
Hansenne, Michel ULg; Laloyaux, Olivier ULg; Mardaga, Solange et al

in Biological Psychology (2004), 67(3), 331-41

Contradictory findings exist concerning the inhibitory function of low frequency repetitive transcranial magnetic stimulation (rTMS). Therefore, the study examines the impact of different duration of low ... [more ▼]

Contradictory findings exist concerning the inhibitory function of low frequency repetitive transcranial magnetic stimulation (rTMS). Therefore, the study examines the impact of different duration of low frequency rTMS on ERPs. In 17 subjects, auditory ERPs were measured before and after 1 Hz rTMS delivered over the left prefrontal cortex during 10 min (600 pulses) and 15 min (900 pulses). Results showed that 15 min of 1 Hz rTMS induced a significant increase of P300 latency. There was no effect for early ERP components (N100, P200 and N200). This study confirms and extends that 1 Hz rTMS produces a real inhibitory effect only when the duration of the stimulation is about 15 min. The data suggest that rTMS modifies the speed of cognitive processing rather than the energetical aspect of information processing, and that cortical inhibition induced by the magnetic stimulation affects principally the controlled cognitive processes and not the automatic ones. [less ▲]

Detailed reference viewed: 38 (5 ULg)
Full Text
Peer Reviewed
See detailRömisches Herrschaftsdenken oder cäsarische Apologie? Gedanken zu Cäsar und nostrum mare
Vanhaegendoren, Koen ULg

in Wiener Humanistische Blätter (2004), 46

Detailed reference viewed: 26 (0 ULg)
Full Text
Peer Reviewed
See detailElectronic and Molecular Properties of an Adsorbed Protein Monolayer Probed by Two-Color Sum-Frequency Generation Spectroscopy
Dreesen, Laurent ULg; Humbert, C.; Sartenaer, Y. et al

in Langmuir (2004), 20(17), 7201-7207

Two-color sum-frequency generation spectroscopy (2C-SFG) is used to probe the molecular and electronic properties of an adsorbed layer of the green fluorescent protein mutant 2 (GFPmut2) on a platinum ... [more ▼]

Two-color sum-frequency generation spectroscopy (2C-SFG) is used to probe the molecular and electronic properties of an adsorbed layer of the green fluorescent protein mutant 2 (GFPmut2) on a platinum (111) substrate. First, the spectroscopic measurements, performed under different polarization combinations, and atomic force microscopy (AFM) show that the GFPmut2 proteins form a fairly ordered monolayer on the platinum surface. Next, the nonlinear spectroscopic data provide evidence of particular coupling phenomena between the GFPmut2 vibrational and electronic properties. This is revealed by the occurrence of two doubly resonant sum-frequency generation processes for molecules having both their Raman and infrared transition moments in a direction perpendicular to the sample plane. Finally, our 2C-SFG analysis reveals two electronic transitions corresponding to the absorption and fluorescence energy levels which are related to two different GFPmut2 conformations: the B (anionic) and I forms, respectively. Their observation and wavelength positions attest the keeping of the GFPmut2 electronic properties upon adsorption on the metallic surface. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Full Text
See detailLa production de gros bois de résineux : une opportunité économique et écologique?
Delahaye, L.; Colson, Vincent ULg; Graux, G. et al

in Parcs & Réserves (2004), 59(4), 28-32

Cette note tente de faire la synthèse d'un colloque organisé par Pro Silva (Belgique-Suisse-Allemagne-France) le 17 sept. 2003 à Sasbachwalden (D) sur le thème "Gros bois résineux : une chance pour la ... [more ▼]

Cette note tente de faire la synthèse d'un colloque organisé par Pro Silva (Belgique-Suisse-Allemagne-France) le 17 sept. 2003 à Sasbachwalden (D) sur le thème "Gros bois résineux : une chance pour la sylvicultute et l'utilisation du bois". L'objectif de ce colloque était de rassembler les connaissances sur les ressources en gros bois en France, en Allemagne du Sud-Ouest et en Suisse, leurs utilisations dans l'industrie et leur évaluation en terme de biodiversité. Ce compte-rendu est complété par quelques réflexions sur la production de gros bois résineux en Région wallonne. [less ▲]

Detailed reference viewed: 62 (9 ULg)
Full Text
Peer Reviewed
See detailAggregate Matching Efficiency: A Stochastic Production Frontier Approach, France 1990–1994
Ibourk, Aomar; Maillard, Bénédicte; Perelman, Sergio ULg et al

in Empirica (2004), 31

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of ... [more ▼]

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of variables meant to capture workers and firms characteristics. The model is estimated on French data covering twenty-two regions from March 1990 till February 1995. Our estimates suggest that aggregate matching efficiency has decreased steadily in the early nineties. There are also wide cross-regional differences. On average, about 30% of the variations of efficiency observed across time and regions can be related to changes in the explanatory variables used in the model. The most important explanatory variables are the proportion of youngsters, females and immigrants in the stock of job seekers. Long-term unemployment has a significant negative effect, population density a significant positive one. The huge decline in the proportion of permanent job offers has apparently little effect on matching efficiency. [less ▲]

Detailed reference viewed: 30 (2 ULg)
Full Text
Peer Reviewed
See detailCancer du pancréas et vertèbre d'ivoire
Guillaume, Thierry ULg; Krzesinski, Jean-Marie ULg; Lambinet, Nadine ULg

in Revue Médicale de Liège (2004), 59(12), 685-687

En résumé, nous avons donc objectivé un adénocarcinome de la tête pancréatique cliniquement asymptomatique suite à la mise en évidence d’une lésion osseuse métastatique condensante douloureuse. Le cas ... [more ▼]

En résumé, nous avons donc objectivé un adénocarcinome de la tête pancréatique cliniquement asymptomatique suite à la mise en évidence d’une lésion osseuse métastatique condensante douloureuse. Le cas d’un adénocarcinome pancréatique révélé par une métastase osseuse surtout condensante, étant relativement rare, nous a paru intéressant à rapporter. [less ▲]

Detailed reference viewed: 270 (4 ULg)
Full Text
Peer Reviewed
See detailHigh-Technology Service Innovation Success: A Decision-Making Perspective
Van Riel, Allard ULg; Lemmink, Jos; Ouwersloot, Hans

in Journal of Product Innovation Management (2004), 21(5), 348-359

Detailed reference viewed: 80 (2 ULg)
Full Text
Peer Reviewed
See detailIdentification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.
Lecut, Christelle ULg; Arocas, Veronique; Ulrichts, Hans et al

in Journal of Biological Chemistry (2004), 279(50), 52293-9

Glycoprotein VI (GPVI) has a crucial role in platelet responses to collagen. Still, little is known about its interaction with its ligands. In binding assays using soluble or cell-expressed human GPVI, we ... [more ▼]

Glycoprotein VI (GPVI) has a crucial role in platelet responses to collagen. Still, little is known about its interaction with its ligands. In binding assays using soluble or cell-expressed human GPVI, we observed that (i) collagen, and the GPVI-specific ligands collagen-related peptides (CRP) and convulxin, competed with one another for the binding to GPVI and (ii) monoclonal antibodies directed against the extracellular part of the human receptor displayed selective inhibitory properties on GPVI interaction with its ligands. Monoclonal antibody 9E18 strongly reduced the binding of GPVI to collagen/CRP, 3F8 inhibited its interaction with convulxin, whereas 9O12 prevented all three interactions. These observations suggest that ligand-binding sites are distinct, exhibiting specific features but at the same time also sharing some common residues participating in the recognition of these ligands. The epitope of 9O12 was mapped by phage display, along with molecular modeling of human GPVI, which allowed the identification of residues within GPVI potentially involved in ligand recognition. Site-directed mutagenesis revealed that valine 34 and leucine 36 are critical for GPVI interaction with collagen and CRP. The loop might thus be part of a collagen/CRP-binding site. [less ▲]

Detailed reference viewed: 19 (6 ULg)
Full Text
Peer Reviewed
See detailInvolvement of glutathione as a mechanism of indirect protection against spontaneous ex vivo apoptosis associated with bovine leukemia virus.
Sanchez Alcaraz, Teresa; Kerkhofs, Pierre; Reichert, Michal et al

in Journal of virology (2004), 78(12),

Detailed reference viewed: 33 (7 ULg)
Full Text
Peer Reviewed
See detailPancreatic autoantibodies in inflammatory bowel disease
Joossens, S.; Vermeire, S.; Van Steen, Kristel ULg et al

in Inflammatory Bowel Diseases (2004), 10(6), 771-777

Background: Autoantibodies against exocrine pancreas (PABs) have been reported to be specific for Crohn's disease (CD), albeit at a low prevalence (30%). We studied PABs in patients with inflammatory ... [more ▼]

Background: Autoantibodies against exocrine pancreas (PABs) have been reported to be specific for Crohn's disease (CD), albeit at a low prevalence (30%). We studied PABs in patients with inflammatory bowel disease (IBD), unaffected family members, and control subjects. Methods: A Belgian study cohort of 575 subjects, including 289 IBD patients (CD, 169 patients; ulcerative colitis [UC], 120 patients), 108 unaffected first-degree relatives, 78 subjects with non-IBD gastrointestinal disorders (gastrointestinal control subjects [GIcos]), and 100 healthy control subjects (Hcos), were tested for PAB by a standardized indirect immunofluorescence method. Results: The prevalence of PABs in this study cohort was 32% for CD, 23.3% for UC, and 22.2% for their unaffected family members (all P < 0.001), compared with 1.3% for GIcos and 0% for Hcos. Two staining patterns could be observed: an intracellular pattern (IC); and an extracellular pattern (EC). The EC was significantly more prevalent in CD patients compared with UC patients (P = 0.014), and higher titers of this pattern were found in CD patients (P = 0.01). Both PAB patterns were negatively associated with stricturing disease behavior of CD (P = 0.021). The IC was associated with familial CD (P = 0.0009) and familial UC (P = 0.0003). Conclusions: The prevalence of PAB found in CD patients in this study was similar to that cited in previous reports. In contrast to these reports, we also found an increased prevalence of PABs in patients with UC and in unaffected first-degree relatives of IBD patients. We observed two main staining patterns, both of which were present in IBD and were associated with specific phenotypes of the disease. [less ▲]

Detailed reference viewed: 13 (4 ULg)
Full Text
See detailLe site de Mitoc-Malu Galben en Moldavie roumaine
Bister, Tamara; Noiret, Pierre ULg

in Art&Fact (2004), 23

Detailed reference viewed: 49 (4 ULg)
Full Text
Peer Reviewed
See detailBaseline health-related quality-of-life data as prognostic factors in a phase III multicentre study of women with metastatic breast cancer
Efficace, F.; Biganzoli, L.; Piccart, M. et al

in European Journal of Cancer (2004), 40(7), 1021-1030

The potential value of baseline health-related quality-of-life (HRQOL) and clinical factors in predicting prognosis was examined using data from an international randomised phase III trial which compared ... [more ▼]

The potential value of baseline health-related quality-of-life (HRQOL) and clinical factors in predicting prognosis was examined using data from an international randomised phase III trial which compared doxorubicin and paclitaxel with doxorubicin and cylophosphamide as first line chemotherapy in 275 women with metastatic breast cancer. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and the related breast module (QLQ-BR23) were used to assess baseline HRQOL data. The Cox proportional-hazards regression model was used for both univariate and multivariate analyses of survival. In the univariate analyses, performance status (P < 0.001) and number of sites involved (P = 0.001) were the most important clinical prognostic factors. The HRQOL variables at baseline most strongly associated with longer survival were better appetite, physical and role functioning, as well as less fatigue (P < 0.001). The final multivariate model retained performance status (P < 0.001) and appetite loss (P = 0.005) as the variables best predicting survival. Substantial loss of appetite was the only independent HRQOL factor predicting poor survival and was strongly correlated (\r\ > 0.5) with fatigue, role and physical functioning. In addition to known clinical factors, appetite loss appears to be a significant prognostic factor for survival in women with metastatic breast cancer. However, the mechanism underlying this association remains to be precisely defined in future studies. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 13 (2 ULg)
Full Text
Peer Reviewed
See detailInfluence of breathing pattern and lung inflation on impulse oscillometry measurements in horses.
Van Erck, Emmanuelle; Votion, Dominique ULg; Kirschvink, Nathalie et al

in Veterinary Journal (2004), 168(3), 259-69

The objective of this paper was to determine if changes in ventilation patterns could influence the outcome of respiratory function measurements performed with our impulse oscillometry system (IOS) in ... [more ▼]

The objective of this paper was to determine if changes in ventilation patterns could influence the outcome of respiratory function measurements performed with our impulse oscillometry system (IOS) in horses. In a first study, IOS tests were performed in vitro on six isolated equine lungs. Lung inflation levels were controlled by modifying depressurisation inside an artificial thorax and different ventilation patterns were imposed. In a second in vivo study, transient variations in breathing pattern were evaluated both with the IOS and a current reference technique (CRT) in five healthy mature horses after an intravenous (i.v.) injection of lobeline hydrochloride. In both studies, respiratory rate (RR, range: 7-42 breaths/min.) and tidal volume (V(T), range: 0.4-25 L) had minor or no influence on IOS parameters. The influence of lung inflation, most marked for resistance at 5 Hz (R(5 Hz)), was limited for the considered physiological range. In vivo, statistical models indicated that maximal changes in pleural pressure (Max Delta Ppl) and peak flows were the main determinants of the variability of the resistance (R(rs)) and the reactance (X(rs)) of the respiratory system. The fourfold increase in baseline Max Delta Ppl and peak flows obtained during hyperpnoea caused a significant increase in R(rs) at 5 and 10 Hz and a decrease in X(rs) at all frequencies. We conclude that IOS parameters are not influenced by tachypnoea, but will reflect alterations in respiratory mechanics caused by hyperpnoeic breathing [less ▲]

Detailed reference viewed: 39 (4 ULg)
Full Text
Peer Reviewed
See detailManagement of the metabolic syndrome.
Scheen, André ULg

in Minerva Endocrinologica (2004), 29(2), 31-45

The metabolic syndrome (MetS) is strongly associated with insulin resistance and consists of a constellation of factors that raise the risk for cardiovascular diseases and diabetes mellitus. Therefore ... [more ▼]

The metabolic syndrome (MetS) is strongly associated with insulin resistance and consists of a constellation of factors that raise the risk for cardiovascular diseases and diabetes mellitus. Therefore, the primary goals of treating MetS are prevention of type 2 diabetes and cardiovascular events. Three levels of intervention may be considered for individuals with MetS : 1) management of underlying risk conditions by controlling weight excess, enhancing regular physical exercise and promoting healthy diet; 2) management of individual risk factors such as dyslipidaemia, hypertension, hyperglycaemia and prothrombotic state; and 3) targeting insulin resistance by using specific insulin sensitizers such as thiazolidinediones. The most important therapeutic intervention effective in subjects with MetS should focus on modest weight reduction and regular leisure-time physical activities. Although lifestyle modification is the first-line therapy, drug therapy may be necessary in many patients to achieve recommended goals regarding lipid profile, blood pressure and blood glucose control. Rather than to use a magic bullet that might fully reverse the underlying cause of the syndrome, one appealing alternative would be to use a so-called "polypill" targeting each of the components of MetS. However, such a polypill should ideally contain numerous molecules that all have shown a potential interest for the management of MetS such as metformin, acarbose, a thiazolidinedione, a statin, a fibrate, an inhibitor of the renin-angiotensin system, aspirin. The growing prevalence and high-risk nature of MetS highlights the need to identify individuals with this condition and to treat them with an aggressive multitargeted approach. [less ▲]

Detailed reference viewed: 237 (2 ULg)
Full Text
See detailHistoire de l'art et archéologie de l'époque préhistorique
Otte, Marcel ULg; Noiret, Pierre ULg

in Art&Fact (2004), 23

Detailed reference viewed: 38 (11 ULg)
Full Text
Peer Reviewed
See detailDrug-eluting stents: meta-analysis in diabetic patients.
Scheen, André ULg; Warzee, Fabian ULg; Legrand, Victor ULg

in European heart journal (2004), 25(23), 2167-82168-9

Detailed reference viewed: 15 (3 ULg)
Full Text
See detailOptimisation des treillis à membrure supérieure variable sur base de la théorie des indicateurs morphologiques
Moureaux, Christine ULg; Latteur, Pierre ULg

in Revue scientifique des instituts supérieurs industriels francophones de Belgique (2004), 18

Detailed reference viewed: 28 (4 ULg)
Full Text
Peer Reviewed
See detailSevere deficiency of glycoprotein VI in a patient with gray platelet syndrome.
Nurden, Paquita; Jandrot-Perrus, Martine; Combrie, Robert et al

in Blood (2004), 104(1), 107-14

We report a novel case of gray platelet syndrome (GPS) where a severe deficiency of the platelet collagen receptor, glycoprotein (GP) VI, accompanies classical symptoms of a low platelet count and ... [more ▼]

We report a novel case of gray platelet syndrome (GPS) where a severe deficiency of the platelet collagen receptor, glycoprotein (GP) VI, accompanies classical symptoms of a low platelet count and platelets lacking alpha-granules. Dense granules were normally present. Platelet aggregation with collagen was severely decreased, as was the response to convulxin (Cvx), a GPVI agonist. Quantitative analysis of GPVI using fluorescein isothiocyanate (FITC)-Cvx in flow cytometry showed its virtual absence on the patient's platelets. The GPVI deficiency was confirmed using monoclonal antibodies in Western blotting and in immunogold labeling on frozen thin sections where internal pools of GPVI were confirmed for normal platelets. The Fc receptor gamma-chain, constitutively associated with GPVI in normal platelets, was present in subnormal amounts, and the phospholipase C gamma 2-dependent activation pathway appeared to function normally. No autoantibodies to GPVI were found in the patient's serum using monoclonal antibody immobilization of platelet antigen (MAIPA). Sequencing of coding regions of the GPVI gene failed to show abnormalities, and mRNA for GPVI was present in the patient's platelets, pointing to a probable acquired defect in GPVI expression. Our results may provide a molecular explanation for the subgroup of patients with severely deficient collagen-induced platelet aggregation as previously described for GPS in the literature. [less ▲]

Detailed reference viewed: 53 (2 ULg)
Full Text
Peer Reviewed
See detailDélinquance routière: armes de choix ou choix des armes?
Dantinne, Michaël ULg

in Revue de Droit Pénal et de Criminologie (2004)

Detailed reference viewed: 73 (20 ULg)
Full Text
Peer Reviewed
See detailSubtype Selective Substrates For Histone Deacetylases
Heltweg, B.; Dequiedt, Franck ULg; Marshall, Bl. et al

in Journal of Medicinal Chemistry (2004), 47(21),

To probe the steric requirements for deacylation, we synthesized lysine-derived small molecule substrates and examined structure-reactivity relationships with various histone deacetylases. Rat liver ... [more ▼]

To probe the steric requirements for deacylation, we synthesized lysine-derived small molecule substrates and examined structure-reactivity relationships with various histone deacetylases. Rat liver, human HeLa, and human recombinant class I and II histone deacetylases (HDACs) as well as human recombinant NAD(+)-dependent SIRT1 (class III enzyme) were used in these studies. A benzyloxycarbonyl substituent on the alpha-amino group yielded the highest conversion rates. Replacing the epsilon-acetyl group with larger lipophilic acyl substituents led to a pronounced decrease in conversion by class I and II enzymes; the class III enzyme displayed a greater tolerance. Incubations with recombinant FLAG-tagged human HDACs 1, 3, and 6 showed a distinct subtype selectivity among small molecule substrates. The subtype selectivity of HDAC inhibitors could be predicted with these substrates and an easily obtainable mixture of HDAC subtypes. [less ▲]

Detailed reference viewed: 24 (6 ULg)
Full Text
Peer Reviewed
See detailLck dephosphorylation at Tyr-394 and inhibition of T cell antigen receptor signaling by Yersinia phosphatase YopH.
Alonso, Andres; Bottini, Nunzio; Bruckner, Shane et al

in Journal of Biological Chemistry (2004), 279(6), 4922-8

A key virulence factor for Yersinia pestis, the etiologic agent of plague, is the tyrosine phosphatase YopH, which the bacterium injects into host cells. We report that treatment of human T lymphocytes ... [more ▼]

A key virulence factor for Yersinia pestis, the etiologic agent of plague, is the tyrosine phosphatase YopH, which the bacterium injects into host cells. We report that treatment of human T lymphocytes with a recombinant membrane-permeable YopH resulted in severe reduction in intracellular tyrosine phosphorylation and inhibition of T cell activation. The primary signal transducer for the T cell antigen receptor, the Lck tyrosine kinase, was specifically precipitated by a substrate-trapping YopH mutant, and Lck was dephosphorylated at its positive regulatory site, Tyr-394, in cells containing active YopH. By turning off Lck, YopH blocks T cell antigen receptor signaling at its very first step, effectively preventing the development of a protective immune response against this lethal bacterium. [less ▲]

Detailed reference viewed: 101 (3 ULg)
Full Text
Peer Reviewed
See detailProbing the origins, diagnosis and treatment of amyloid diseases using antibodies.
Dumoulin, Mireille ULg; Dobson, Christopher

in Biochimie (2004), 86

The deposition of proteins in the form of amyloid fibrils is the characteristic feature of more than 20 medical conditions affecting the central nervous system or a variety of peripheral tissues. These ... [more ▼]

The deposition of proteins in the form of amyloid fibrils is the characteristic feature of more than 20 medical conditions affecting the central nervous system or a variety of peripheral tissues. These disorders, which include Alzheimer's disease, the prion diseases and type II diabetes, are of enormous importance in the context of present-day human health and welfare. Extensive research is therefore being carried out to define the molecular details of the mechanism of the pathological conversion of amyloidogenic proteins from their soluble forms into fibrillar structures. This review focuses on recent studies that demonstrate the power of using antibodies or antibody fragments to probe the process of fibril formation, and discusses the emerging potential of these species as diagnostic and therapeutic agents. [less ▲]

Detailed reference viewed: 51 (1 ULg)
Full Text
Peer Reviewed
See detailResponse to novelty as a predictor for drug effects: the pitfalls of some correlational studies
Quertemont, Etienne ULg; Brabant, Christian ULg; Tirelli, Ezio ULg

in Psychopharmacology (2004), 173(1-2), 221-224

In recent years, an individual's response to novelty has been postulated to predict its response to drugs of abuse and particularly to their addictive properties (Piazza et al. 1990). The hypothesis of a ... [more ▼]

In recent years, an individual's response to novelty has been postulated to predict its response to drugs of abuse and particularly to their addictive properties (Piazza et al. 1990). The hypothesis of a relationship between the response to novelty and the effects of addictive drugs was supported by a number of animal studies that reported correlations between responses to a novel environment and various effects of drugs, such as their locomotor stimulant effects, their reinforcing action or their propensity to be self-administered (Piazza et al. 1990; Klebaur et al. 2001; Carey et al. 2003; Shimosato and Watanabe 2003). Most of these studies concluded that an animal's response to novelty predicts its subsequent response to drug administration. However, correlational studies are sometimes hampered by methodological and statistical weaknesses that preclude a proper interpretation of the results. The two most frequent weaknesses are the lack of consideration for the correlation in the control group and the calculation of spurious correlations. [less ▲]

Detailed reference viewed: 29 (3 ULg)
Full Text
Peer Reviewed
See detailAdaptation et test d'un nez électronique pour suivre en continu la nuisance olfactive générée par un centre de compostage
Ledent, Catherine; Dauby, B.; Nicolas, Jacques ULg et al

in Revue scientifique des instituts supérieurs industriels libres francophones (2004), 18

L'article présente le travail de fin d'études de Catherine Ledent. Celui-ci a consisté à la mise au point et au test sur le terrain (sur le centre de compostage à Habay) d'un nez électronique destiné à ... [more ▼]

L'article présente le travail de fin d'études de Catherine Ledent. Celui-ci a consisté à la mise au point et au test sur le terrain (sur le centre de compostage à Habay) d'un nez électronique destiné à être placé en continu sur un site industriel, de manière à détecter des occurrences d'odeur. Le prototype existant a été adapté de manière à satisfaire aux exigences du terrain. Par exemple, une régulation thermique de la chambre des capteurs a permis de s'affranchir des variations de température de l'ambiance. La phase de validation sur le terrain fut la plus exigeante: elle nécessitait en effet une présence constante de l'étudiante sur le terrain, de manière à identifier les causes possibles de variation des capteurs. En finale, le système a montré d'excellentes performances et peut servir de base à un développement technologique ultérieur. [less ▲]

Detailed reference viewed: 61 (2 ULg)
Full Text
Peer Reviewed
See detail1903-2003. Cent ans de géographie à l’Université de Liège : changements et permanences
Merenne-Schoumaker, Bernadette ULg

in Bulletin de la Société Géographique de Liège (2004), (44), 125-127

Address of the 100th anniversary of the Institute of Geography, University of Liege

Detailed reference viewed: 21 (2 ULg)
Full Text
Peer Reviewed
See detailSuppression Of Tumor Growth And Cell Proliferation By P13(Ii), A Mitochondrial Protein Of Human T Cell Leukemia Virus Type 1
Silic-Benussi, M.; Cavallari, L.; Zorzan, T. et al

in Proceedings of the National Academy of Sciences of the United States of America (2004), 101(17),

Detailed reference viewed: 13 (3 ULg)
Full Text
See detailThe [56,4+] baryon multiplet in the 1/N(c) expansion of QCD
Matagne, Nicolas; Stancu, Floarea ULg

in Large Nc QCD 2004 (2004)

We use the $1/N_c$ expansion of QCD to analyze the spectrum of positive parity resonances with strangeness $S = 0, -1, -2$ and -3 in the 2--3 GeV mass region, supposed to belong to the $[\textbf{56},4 ... [more ▼]

We use the $1/N_c$ expansion of QCD to analyze the spectrum of positive parity resonances with strangeness $S = 0, -1, -2$ and -3 in the 2--3 GeV mass region, supposed to belong to the $[\textbf{56},4^+]$ multiplet. The mass operator is similar to that of $[\textbf{56},2^+]$, previously studied in the literature. The analysis of the latter is revisited. In the $[\textbf{56},4^+]$ multiplet we find that the spin-spin term brings the dominant contribution and that the spin-orbit term is entirely negligible in the hyperfine interaction, in agreement with constituent quark model results. More data are strongly desirable, especially in the strange sector in order to fully exploit the power of this approach. [less ▲]

Detailed reference viewed: 26 (3 ULg)
Full Text
Peer Reviewed
See detailRedox state of endogenous coenzyme q modulates the inhibition of linoleic acid-induced uncoupling by guanosine triphosphate in isolated skeletal muscle mitochondria.
Jarmuszkiewicz, W.; Navet, R.; Alberici, L. et al

in Journal of Bioenergetics & Biomembranes (2004), 36

The skeletal muscle mitochondria contain two isoforms of uncoupling protein, UCP2 and mainly UCP3, which had been shown to be activated by free fatty acids and inhibited by purine nucleotides in ... [more ▼]

The skeletal muscle mitochondria contain two isoforms of uncoupling protein, UCP2 and mainly UCP3, which had been shown to be activated by free fatty acids and inhibited by purine nucleotides in reconstituted systems. On the contrary in isolated mitochondria, the protonophoretic action of muscle UCPs had failed to be demonstrated in the absence of superoxide production. We showed here for the first time that muscle UCPs were activated in state 3 respiration by linoleic acid and dissipated energy from oxidative phosphorylation by decreasing the ADP/O ratio. The efficiency of UCPs in mitochondrial uncoupling increased when the state 3 respiratory rate decreased. The inhibition of the linoleic acid-induced uncoupling by a purine nucleotide (GTP), was not observed in state 4 respiration, in uninhibited state 3 respiration, as well as in state 3 respiration inhibited by complex III inhibitors. On the contrary, the progressive inhibition of state 3 respiration by n -butyl malonate, which inhibits the uptake of succinate, led to a full inhibitory effect of GTP. Therefore, as the inhibitory effect of GTP was observed only when the reduced state of coenzyme Q was decreased, we propose that the coenzyme Q redox state could be a metabolic sensor that modulates the purine nucleotide inhibition of FFA-activated UCPs in muscle mitochondria. [less ▲]

Detailed reference viewed: 20 (3 ULg)
Full Text
Peer Reviewed
See detailFacteurs protecteurs familiaux de la deliquance juvenile feminine
Rasseneur, D.; Born, Michel ULg

in Revue de Psychoéducation (2004), 33(2), 321-333

Detailed reference viewed: 103 (12 ULg)
Full Text
Peer Reviewed
See detailNew service development in high tech sectors: A decision making perspective
Van Riel, Allard ULg; Lievens, Annouk

in International Journal of Service Industry Management (2004), 15(1), 72-101

Detailed reference viewed: 39 (3 ULg)
Full Text
Peer Reviewed
See detailL'annulation des sentences arbitrales
Caprasse, Olivier ULg; Hanotiau, Bernard

in Journal des Tribunaux (2004)

Detailed reference viewed: 132 (8 ULg)
Full Text
Peer Reviewed
See detailCommunity-based wildlife management in Burkina Faso : the experiments of the Nazinga Ranch and W park
Vermeulen, Cédric ULg

in Game and Wildlife Science (2004), 21(3), 313-326

Le Burkina Faso reste le seul pays d’Afrique occidentale à posséder une législation où, au moins légalement, la gestion cynégétique de la faune sauvage par les populations locales est devenue une réalité ... [more ▼]

Le Burkina Faso reste le seul pays d’Afrique occidentale à posséder une législation où, au moins légalement, la gestion cynégétique de la faune sauvage par les populations locales est devenue une réalité. Les textes de loi prévoient en effet la possibilité pour les populations de délimiter sur leurs terroirs des zones dévolues à la chasse commerciale, d’y faire venir des chasseurs et de rétrocéder à l’État la part des recettes qui lui est due. La loi prévoit également la constitution de Comités Villageois de Gestion de la Faune (CVGF), structures rattachées aux Comités Villageois de Gestion de Terroir (CVGT) et reconnues dans le processus de décentralisation en cours. L’opportunité de construire une conservation de la faune sauvage servant directement le développement local existe donc. Dans la pratique, il reste encore beaucoup d’étapes à franchir avant que des Zones Villageoises d’Intérêt Cynégétique (ZOVIC) réellement autonomes et indépendantes financièrement ne prennent corps. Les résistances au niveau institutionnel et privé ne manquent pas, et seule la démonstration de la capacité des populations locales à relever ce défi pourra faire évoluer les mentalités. Les premières ZOVIC ont été mises en place à partir de 2000 dans les périphéries du Ranch de Nazinga (1 276 ha de ZOVIC) et du Parc du W (1 790 ha de ZOVIC). Ces expériences ont été la source de riches enseignements dans des contextes particuliers de tensions foncières, liés soit à une importante immigration humaine dans le cas de la ZOVIC du Ranch de Nazinga, soit à une course au coton dans celui des ZOVIC du Parc du W. Elles ont montré que la gestion cynégétique villageoise nécessitait des besoins de formation importants et qu’elle devait faire face aux classiques enjeux techniques (préservation de l’habitat, gestion de la faune, quotas d’abattage dont l’application reste parfois aléatoire en raison de la petite taille des zones délimitées, etc.). Les ZOVIC ont aussi soulevé le problème du rapport de la communauté rurale à l’espace et au foncier, celui fonctionnement des structures locales de gestion et de leur fusion avec le système politique coutumier local, et celui de la réelle volonté de l’univers administratif et privé de la chasse à partager la rente cynégétique avec les populations locales. La gestion cynégétique villageoise doit donc être comprise comme un exercice de démocratie directe et comme la voie vers la gestion globale des terroirs villageois. Au-delà de l’aspect technique lié à la faune et à sa gestion durable, la réussite de ces expériences devrait également annoncer la pratique d’une chasse plus sociale et plus équitable, où les populations locales participeraient davantage au partage du flux financier. [less ▲]

Detailed reference viewed: 113 (13 ULg)
Full Text
Peer Reviewed
See detailType trait (co)variance components for five dairy breeds
Wiggans, G. R.; Gengler, Nicolas ULg; Wright, J. R.

in Journal of Dairy Science (2004), 87(7), 2324-2330

(Co)variance components were estimated for final score and 14 or 15 linear type traits for the Ayrshire, Brown Swiss, Guernsey, Jersey, and Milking Shorthorn breeds. Appraisals from 1995 or later were ... [more ▼]

(Co)variance components were estimated for final score and 14 or 15 linear type traits for the Ayrshire, Brown Swiss, Guernsey, Jersey, and Milking Shorthorn breeds. Appraisals from 1995 or later were used. New estimates were calculated to accommodate changes in scoring of traits and because of a change from multiplicative to additive adjustment for age and lactation stage. The adjustment method was changed for better support of the adjustment for heterogeneous variance within iteration, which was implemented in 2002. The largest changes in heritability were an increase of 0.10 for rump angle for Milking Shorthorns and a decrease of 0.11 for udder depth for Jerseys. The new estimates of (co)variance components should provide improved accuracy of type evaluations, particularly for traits that have had variance changes over time. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailThe Bryophyte Layer In A Calcareous Grassland After A Decade Of Contrasting Mowing Regimes
Vanderpoorten, Alain ULg; Delescaille, Lm.; Jacquemart, Al.

in Biological Conservation (2004), 117(1),

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailPrediction of daily milk, fat, and protein production by a random regression test-day model
Mayeres, P.; Stoll, J.; Bormann, J. et al

in Journal of Dairy Science (2004), 87(6), 1925-1933

Test-day genetic evaluation models have many advantages compared with those based on 305-d lactations; however, the possible use of test-day model (TDM) results for herd management purposes has not been ... [more ▼]

Test-day genetic evaluation models have many advantages compared with those based on 305-d lactations; however, the possible use of test-day model (TDM) results for herd management purposes has not been emphasized. The aim of this paper was to study the ability of a TDM to predict production for the next test day and for the entire lactation. Predictions of future production and detection of outliers are important factors for herd management (e. g., detection of health and management problems and compliance with quota). Because it is not possible to predict the herd-test-day (HTD) effect per se, the fixed HTD effect was split into 3 new effects: a fixed herd-test month-period effect, a fixed herd-year effect, and a random HTD effect. These new effects allow the prediction of future production for improvement of herd management. Predicted test-day yields were compared with observed yields, and the mean prediction error computed across herds was found to be close to zero. Predictions of performance records at the herd level were even more precise. Discarding herds enrolled in milk recording for <1 yr and animals with very few tests in the evaluation file improved correlations between predicted and observed yields at the next test day (correlation of 0.864 for milk in first-lactation cows as compared with a correlation of 0.821 with no records eliminated). Correlations with the observed 305-d production ranged from 0.575 to 1 for predictions based on 0 to 10 test-day records, respectively. Similar results were found for second and third lactation records for milk and milk components. These findings demonstrate the predictive ability of a TDM. [less ▲]

Detailed reference viewed: 39 (5 ULg)
Full Text
Peer Reviewed
See detailThe Pyoverdins Of Pseudomonas Syringae And Pseudomonas Cichorii
Bultreys, A.; Gheysen, I.; Wathelet, Bernard ULg et al

in Zeitschrift Fur Naturforschung C-A Journal of Biosciences (2004), 59(9-10),

Detailed reference viewed: 22 (2 ULg)
Full Text
Peer Reviewed
See detailComparison of external morphological traits of newborns to inner morphological traits of the dam in the double-muscled Belgian Blue Beef breed
Coopman, F.; Gengler, Nicolas ULg; Groen, A. F. et al

in Journal of Animal Breeding & Genetics (2004), 121(2), 128-134

In the double-muscled (DM) Belgian Blue Beef (BBB) breed, caesarean section (CS) is used as a routine management tool to prevent dystocia. This practice is criticized on animal welfare grounds. With ... [more ▼]

In the double-muscled (DM) Belgian Blue Beef (BBB) breed, caesarean section (CS) is used as a routine management tool to prevent dystocia. This practice is criticized on animal welfare grounds. With unassisted (natural) births, difficulties arise because of disproportion between the sizes of the newborn and inner pelvic sizes of the dam. In this study external morphological traits of newborns are compared with inner morphological traits of the dam. Results of this study indicate that in the DM-BBB, CS is the only means to successful calving. Therefore, no calving ease scores are available to select for less dystocia in this breed. Selection for fewer CS must be achieved by focusing on lower birth weight (BW) and decreased muscular conformation at birth, both having a sufficiently high heritability. Simultaneously, pelvic sizes of the dam should be increased. It is very likely that the look of the DM-BBB will change when selecting for less dystocia. [less ▲]

Detailed reference viewed: 21 (2 ULg)
Full Text
Peer Reviewed
See detailQu'est-ce qu'un phénomène?
Seron, Denis ULg

in Etudes Phénoménologiques (2004), 39-40

Detailed reference viewed: 87 (2 ULg)
Full Text
Peer Reviewed
See detailLe bilan azoté dans les exploitations porcines wallonnes : entre contraintes environnementales et qualité différenciée.
Degre, Aurore ULg; Verheve, Didier; Debouche, Charles ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2004), 8(2), 119-124

Detailed reference viewed: 36 (10 ULg)
Full Text
Peer Reviewed
See detailUne matrice conceptuelle de la négociation. Du marchandage à la négociation valorielle
Kuty, Olgierd ULg

in Négociations (2004), 1(1), 45-62

Detailed reference viewed: 117 (6 ULg)
Full Text
Peer Reviewed
See detailGenetic structuralism, psychological sociology and pragmatic social actor theory, Proposals for a convergence of French sociologies
Frère, Bruno ULg

in Theory, Culture & Society (2004), 21(3), 85-99

This paper would like to show that Wittgenstein and Freud have exerted a considerable - though narrow - influence on Bourdieu's sociology. But they also pervade the theoretical development of two other ... [more ▼]

This paper would like to show that Wittgenstein and Freud have exerted a considerable - though narrow - influence on Bourdieu's sociology. But they also pervade the theoretical development of two other currents, which have emerged in French Sociology in the last few years, and were developed by L. Boltanski and L. Thevenot, on the one hand, and B. Lahire, on the other. Although they do not make it explicit, the advocates of these two currents have nevertheless been influenced by Wittgenstein and Freud. Thus Boltanski has drawn on Wittgenstein to develop a sociology which gives primacy to the social actor's interpretation of his or her situation through lay theorising. Lahire's work clearly pays a debt to Freud with his psychological sociology. It would therefore be interesting, in the first instance, to tease out how Wittgenstein and Freud, respectively, have influenced these two systems to demonstrate that they can indeed be used to generate new sociological currents, other than Bourdieu's own. This would then allow us to explore how they could be used to fill any gaps in Bourdieu's work, thus giving the latter renewed relevance and staunching its stagnating tendencies. But, ultimately, this analysis aims to show how Wittgenstein’s and Freud's theoretical influences can lead the way towards a theoretical synthesis between Bourdieu's critical sociology, Boltanski's social actor theory and Lahire's psychological sociology. Currently, these three currents operate independently of each other, without any kind of dialogue. And yet, far from being incompatible, these sociologies offer opportunities for exploring how they might complement each other and for mutual enrichment. [less ▲]

Detailed reference viewed: 113 (5 ULg)
Full Text
Peer Reviewed
See detailFurther evidence of the multi-dimensionality of hallucinatory predisposition: factor structure of a modified version of the Launay-Slade Hallucinations Scale in a normal sample
Laroi, Frank ULg; Marczewski, P.; Van der Linden, Martial ULg

in European Psychiatry (2004), 19

Recent years has seen an increasing interest in the hallucinatory experience, including investigations of its phenomenological prevalence and character both in pathological and normal (predisposed ... [more ▼]

Recent years has seen an increasing interest in the hallucinatory experience, including investigations of its phenomenological prevalence and character both in pathological and normal (predisposed) populations. We investigated the multi-dimensionality of hallucinatory experiences in 265 subjects from the normal population, who completed a modified version of the Launay-Slade Hallucinations Scale. Principal components analysis was performed on the data. Four factors were obtained loading on items reflecting (1) sleep-related hallucinatory experiences (2) vivid daydreams (3) intrusive thoughts or realness of thought and (4) auditory hallucinations. The results offer further evidence of the multi-dimensionality of hallucinatory disposition in the normal population. Directions for future research in hallucinatory predisposition are discussed. <LF>(C) 2003 Elsevier SAS. All rights reserved. [less ▲]

Detailed reference viewed: 73 (6 ULg)
Full Text
Peer Reviewed
See detailMR2048151, Sergeev, Y. A. and Swailes, D. C. and Petrie, C. J. S., Stability of uniform fluidization revisited; Physica A
Rochus, Pierre ULg

in Mathematical Reviews [=MR] (2004), 335(1-2), 9--34

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailRecommandations de l'ESH-ESC 2003 pour la prise en charge de l'hypertension artérielle en médecine générale
Persu, Alexandre; Krzesinski, Jean-Marie ULg; Van de Borne, Philippe

in Revue Médicale de Liège (2004), 59(9), 489-496

Guidelines for the management of arterial hypertension are regularly updated. This article summarizes the last international guidelines in this field published last year. The decision to initiate an ... [more ▼]

Guidelines for the management of arterial hypertension are regularly updated. This article summarizes the last international guidelines in this field published last year. The decision to initiate an antihypertensive treatment will not only depend on blood pressure [less ▲]

Detailed reference viewed: 176 (4 ULg)
Full Text
Peer Reviewed
See detailEffect Of Pig Bodyweight On Ileal Amino Acid Endogenous Losses After Ingestion Of A Protein-Free Diet Enriched In Pea Inner Fibre Isolates
Leterme, Pascal; Thewis, André ULg

in Reproduction Nutrition Development (2004), 44(5), 407-417

The present study was conducted to evaluate whether bodyweight and the micronisation of dietary fibre affect the endogenous nitrogen and amino acid losses (ENL and EAAL) in pigs. The effect of the ... [more ▼]

The present study was conducted to evaluate whether bodyweight and the micronisation of dietary fibre affect the endogenous nitrogen and amino acid losses (ENL and EAAL) in pigs. The effect of the micronising process was tested by providing pigs with 90 g DM·kg–1 BW0.75 of a N-free diet supplemented with isolated pea inner fibres, presented in native or micronised form and with a water-holding capacity of 12 and 4 g water·g–1 DM, respectively. ENL and EAAL were measured on pigs weighing 24, 62 and 105 kg. In all cases, daily ENL increased linearly (P < 0.05) with BW, for the majority of the AA and total N. As BW increased, daily ENL, total EAAL and the majority of EAAL increased linearly independently of micronisation (P < 0.05). When expressed per kg DMI, total EAAL and the majority of each EAA decreased curvilinearly and reached nadir at around 100 kg BW. For ENL expressed per kg DMI, micronisation resulted in a curvilinear decrease with increasing BW, as compared to a linear decrease for pigs fed the native pea fibre diet (non-micronised). Micronisation of pea inner fibres did not decrease ENL or EAAL daily, except for proline. When the losses were expressed as g·k–1g DMI, micronisation did not decrease ENL but decreased (P < 0.05) endogenous losses for a majority of AA as well as for total AA. The results suggest that small pigs excrete more endogenous N per kg DMI than large pigs and that pea fibre micronisation reduces EAAL but not ENL when expressed per kg DMI. [less ▲]

Detailed reference viewed: 27 (1 ULg)