Antiinflammatory Prodelphinidins from Black Currant (Ribes nigrum) LeavesTits, Monique ; Angenot, Luc ; Damas, Jacques et alin Planta Medica (1991), 57(Supplement issue 2), 134 In a study to select anti-inflammatory medicinal plants, we have observed that extracts of Ribes nigrum significantly inhibited at a dose of 50mg/kg i.p. the carrageenan rat paw edema. We have now proved ... [more ▼] In a study to select anti-inflammatory medicinal plants, we have observed that extracts of Ribes nigrum significantly inhibited at a dose of 50mg/kg i.p. the carrageenan rat paw edema. We have now proved that the most active fractions contained proanthocyanidins . In the present study, we report on the isolation of three bioactive compounds: two prodelphinidins dimers and a new trimeric one. [less ▲] Detailed reference viewed: 57 (2 ULg) Un exemple d'étude dendrochronologique: la charpente de la chapelle Saint_hubert à Weweler (Burg-Reuland)Hoffsummer, Patrick ![]() in Bulletin de la Fondation Vanhove-Vonneche (1991), 3 Detailed reference viewed: 6 (0 ULg) The amino acid (157-197) peptide segment of bovine leukemia virus p34tax encompass a leucine-rich globally neutral activation domain.Willems, Luc ; Kettmann, Richard ; in Oncogene (1991), 6(1), 159-63 The specific DNA-binding Gal4 amino-terminal portion (amino acids 1 to 147) was fused to protein segments of BLV transactivator p34tax and tested for its capacity to activate CAT-gene expression in ... [more ▼] The specific DNA-binding Gal4 amino-terminal portion (amino acids 1 to 147) was fused to protein segments of BLV transactivator p34tax and tested for its capacity to activate CAT-gene expression in mammalian cells. The p34tax peptide segment 157 to 197 encompasses an activating region. The segment is approximately located in the middle of p34tax and is globally neutral (net charge zero). The tax (157-197) domain contains 24% of leucine residues, possibly involved in heterologous protein interactions. [less ▲] Detailed reference viewed: 12 (0 ULg) Question sociale et politique pontificale. L'itinéraire d'un démocrate chrétien: Antoine Pottier (1849-1923)Jadoulle, Jean-Louis ![]() in Revue belge de philologie et d'histoire (1991), t. LXIX(n°2), 300-321 Detailed reference viewed: 8 (0 ULg) Les innovations dans l'intervention sociale et la justice des mineurs en BelgiqueBorn, Michel ![]() in Revue Internationale de Criminologie et de Police Technique (1991), 4 Detailed reference viewed: 6 (1 ULg) Interprétation et rectification des jugements répressifsMasset, Adrien ![]() in Revue de Jurisprudence de Liège, Mons et Bruxelles (1991) Detailed reference viewed: 33 (1 ULg) Recension bibliographique de "Allardi J., P. Keith (coord.) : Atlas préliminaire des poissons d'eau douce de France".Poncin, Pascal ![]() in Cahiers d'Ethologie (1991), 11(4), 515 Detailed reference viewed: 1 (0 ULg) Le type toponymique "mouchenière"Boutier, Marie-Guy ![]() in Nouvelle Revue d'Onomastique (1991), 17/18 Detailed reference viewed: 6 (0 ULg) Recension bibliographique de "Halen H., Rosado Couoh J.L. et Meyer J. : Caractéristiques et fonctionnement d'un écosystème agro-piscicole aménagé dans les marais du Tabasco (Mexique)".Poncin, Pascal ![]() in Cahiers d'Ethologie (1991), 11(4), 518 Detailed reference viewed: 2 (0 ULg) Polarization correction to the electrostatic potential at the CNDO and theab initio level. Influence of the basis set expansionDehareng, Dominique ; Dive, Georges ; Ghuysen, Jean-Marie ![]() in Theoretica Chimica Acta (1991), 79(2), 141-152 The influence of the basis set on the electrostatic potential corrected for polarization has been studied for H2S, CH3SH and COHCH2SH. The position and deepness of the minima and the height of the barrier ... [more ▼] The influence of the basis set on the electrostatic potential corrected for polarization has been studied for H2S, CH3SH and COHCH2SH. The position and deepness of the minima and the height of the barrier between symmetric minima is discussed at both the deorthogonalized CNDO/2 and ab initio levels within STO-3G, 3-21G, 4-31G, 6-31G and 6-311G basis sets. The calculation of the electrostatic potential and corrected one using CNDO deorthogonalized coefficients including 3d orbitals has been applied at the first time on sulfur-containing molecules. The influence of polarization and diffuse functions has also been analysed and the incidence of the polarization correction on the relative proton affinity in NH2(CH2)3NHCH3 and in the adenine molecule has been investigated at the CNDO and ab initio levels. At both levels, the relative proton affinity of several basic sites in the same molecule can be qualitatively expressed without inclusion of the polarization correction except in the case of substituted amines. [less ▲] Detailed reference viewed: 14 (1 ULg) Colocalization of immunoreactive oxytocin, vasopressin and interleukin-1 in human thymic epithelial neuroendocrine cells; Geenen, Vincent ; Schoenen, Jean et alin Brain, Behavior & Immunity (1991), 5 Detailed reference viewed: 1 (0 ULg) Un témoignage antérieur à Celse sur l’opération du coloboma : P. bibl. univ. Giss. IV.44Marganne, Marie-Hélène ![]() in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1991), 66 Detailed reference viewed: 5 (0 ULg) Le test ELISA, une nouvelle voie rapide de determination de residus d'herbicides dans le sol. Application au cas de l'isoproturon.; ; et al in Mededelingen van de Faculteit Landbouwwetenschappen (Rijksuniversiteit te Gent) (1991), 56(3a), Detailed reference viewed: 26 (1 ULg) Le point sur l'evolution dans le domaine des formulations.Schiffers, Bruno ; in Parasitica (1991), 47(2-3), Detailed reference viewed: 10 (2 ULg) Bijlokekaai: ZiekenzaalHoffsummer, Patrick ; ; in Stadsarcheologie (1991), 15(1), 56-57 Detailed reference viewed: 2 (0 ULg) Importance de l'axe hypophyso-hepatique dans le regulation hormonale de la croissance chez le bovin.Renaville, Robert ; Portetelle, Daniel ; et alin Bulletin des Recherches Agronomiques de Gembloux (1991), 26(2), Detailed reference viewed: 12 (3 ULg) Fluid inclusions in charnockites from the Bjerkreim-Sokndal massif (Rogaland, southwestern Norway): fluid origin and in situ evolution; ; Duchesne, Jean-Clair et alin Contributions to Mineralogy & Petrology (1991), 108 Detailed reference viewed: 13 (1 ULg) Generation of bovine multisite haplotypes using random cosmids; Georges, Michel ![]() in Genomics (1991), 10 One hundred ten random cosmids were used to probe Southern blots of DNA from nine unrelated cattle digested with 12 restriction enzymes. Although only one-third of the expected fragments were explored, 85 ... [more ▼] One hundred ten random cosmids were used to probe Southern blots of DNA from nine unrelated cattle digested with 12 restriction enzymes. Although only one-third of the expected fragments were explored, 85% of the cosmids revealed at least one polymorphism. The mean heterozygosity of the generated haplotypes was estimated at 51.9%. A surprisingly high proportion of polymorphisms (approximately 25%) was attributed to insertion-deletion events, compensating for the lower level of nucleotide diversity observed in cattle (pi approximately 0.0007) compared to that in human. The mutation rate at cytosines in the CpG dinucleotide was estimated approximately 10 times higher than that at other nucleotides. When used in linkage studies, the generated markers should cover approximately 50% of the bovine genome. [less ▲] Detailed reference viewed: 11 (1 ULg) Adenohypophysis hormone gene products in 14 pituitary adenomas: analysis by immunohistochemistry and northern blotting.Scippo, Marie-Louise ; Beckers, Albert ; Frankenne, Francis et alin Archives Internationales de Physiologie, de Biochimie et de Biophysique (1991), 99(2), 135-40 We investigated 14 pituitary adenomas (10 silent adenomas; 3 prolactinomas and one GH-secreting tumor) for the presence of hormone gene transcripts (Northern blot) as well as for translation products ... [more ▼] We investigated 14 pituitary adenomas (10 silent adenomas; 3 prolactinomas and one GH-secreting tumor) for the presence of hormone gene transcripts (Northern blot) as well as for translation products (immunohistochemistry). The GH-secreting tumor was shown to express the genes coding for GH and PRL and to synthesize the corresponding hormones. In the cases of prolactinomas, immunohistochemical data demonstrated the synthesis of prolactin only. In addition to the PRL gene, Northern blot analysis revealed the transcription of the alpha-subunit gene in one case. Hormone genes were found to be expressed in 7 out of the 10 silent tumors, whereas no hormone synthesis was detected in any of these tissues. LH-beta mRNA was found in 3 cases, FSH-beta mRNA in 5 cases and alpha-subunit gene was shown to be expressed in one case. Surprisingly, the level of expression of the FSH-beta gene was higher than in normal tissue. This study confirms that some so called "silent" adenomas are expressing alpha- and/or beta-subunit glycoprotein hormone genes, even if no hormone is synthesized. The therapeutic action of bromocriptine described in some "silent" adenomas cases could be related to that hormone gene expression potentiality. [less ▲] Detailed reference viewed: 41 (8 ULg) Biodegradation, drug release mechanism and physiological activity of a protein's sustained release system; Beckers, Jean-François ; et alin Proceedings International Symposium Control. Rel.Bioact. Mater. (1991) Detailed reference viewed: 18 (1 ULg) Absence de benefice de l'administration intermittente de l'insuline lors d'un traitement par pompe a perfusion sous-cutanee chez le diabetique de type-1.Lilet, Henri ; ; Bodson, Arthur et alin Diabète & Métabolisme (1991), 17(3), 363-72 Our study is based on two constatations: 1) Hyperinsulinaemia, a possible atherogenic factor, is frequent under continuous subcutaneous insulin infusion. 2) Pulsatile intravenous insulin delivery improve ... [more ▼] Our study is based on two constatations: 1) Hyperinsulinaemia, a possible atherogenic factor, is frequent under continuous subcutaneous insulin infusion. 2) Pulsatile intravenous insulin delivery improve the insulin's hypoglycaemic activity. To test if equivalent metabolic control can be obtained with a reduced intermittent subcutaneous infused insulin dose, we compared nocturnal metabolic control of 8 c-peptide negative type 1 diabetic patients under three experimental conditions: Continuous usual dose test (1.0 +/- 0.1 u/h); Intermittent half dose test (1.0 +/- 0.1 u/h, 30 min/h); Continuous half dose test (0.5 +/- 0.05 u/h) Five parameters were monitored: blood glucose, plasma free insulin and beta-hydroxy-butyrate, free fatty acid and glycerol plasma level. No significant differences were found between intermittent and continuous half-dose tests. We conclude that, in our experimental conditions, intermittent subcutaneous insulin infusion does not reduce the metabolic degradation induced by insulin dose reduction. [less ▲] Detailed reference viewed: 27 (1 ULg) Malitrah : Une formation en alternance dans l'enseignement professionnel spécial de plein exercice. Présentation d'un projetBeckers, Jacqueline ![]() in Education Permanente (1991), 222 Detailed reference viewed: 4 (2 ULg) Description de 70 souches d'Escherichia coli d'origine bovine possédant les gènes des vérotoxines; Daube, Georges ; et alin Annales de Médecine Vétérinaire (1991), 135 Detailed reference viewed: 14 (0 ULg) Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.Pierard, Claudine ; Colige, Alain ; Arrese Estrada, Jorge et alin Dermatologica (1991), 183(1), 7-9 We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of ... [more ▼] We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of keratinocytes and eccrine secretory cells. In some samples, a nuclear labelling was evidenced in these type of cells. There is a close resemblance in the topographical distribution of these cells with nuclear labelling and those synthesizing DNA under phytohaemagglutinin stimulation. [less ▲] Detailed reference viewed: 6 (1 ULg) Apport de l'endocrinologie en selection laitiere bovine.Renaville, Robert ; ; et alin Animal Genetic Resources Information (1991), (8), Detailed reference viewed: 8 (2 ULg) Fast double antibody radioimmunoassay of human granulocyte myeloperoxidase and its application to plasma.Pincemail, Joël ; ; Deby, Christiane et alin Journal of Immunological Methods (1991), 137(2), 181-191 The haem enzyme myeloperoxidase (MPO) (EC 1.11.1.7) with a spectral A430/A280 ratio greater than 0.7 and a specific activity of 125 U/mg was purified from isolated human neutrophils. To obtain a ... [more ▼] The haem enzyme myeloperoxidase (MPO) (EC 1.11.1.7) with a spectral A430/A280 ratio greater than 0.7 and a specific activity of 125 U/mg was purified from isolated human neutrophils. To obtain a radioimmunoassay (RIA) for this enzyme, a specific antiserum against human neutrophil MPO was raised in rabbits and used at an initial dilution of 1/10,000. MPO labelled with 125iodine by a technique of self-labelling in the presence of H2O2, had a specific activity of 24 mCi/mg. After incubation at room temperature (2 h) and separation by double antibody precipitation in the presence of polyethylene glycol, the sensitivity of the RIA was 21 ng/ml. The RIA showed good precision and accuracy with intra- and interassay coefficients of variation of less than 7% for MPO concentrations ranging from 100 to 800 ng/ml, and satisfactory recoveries of known amounts of exogenous MPO in plasma. For the measurement of MPO in blood, the best sampling technique was to collect blood into EDTA. Rapid centrifugation (within 20 min) was necessary for blood collected into heparin. Mean MPO values in normal individuals were 340 +/- 98 ng/ml in EDTA plasma (n = 152) and 332 +/- 82 ng/ml in heparinized plasma (n = 34). When MPO was measured 12-6 h after injury in critically ill patients high values (above 1000 ng/ml) were found in 6/15 patients with multiple injuries. In patients with sepsis (n = 22), MPO values were always above 1000 ng/ml. [less ▲] Detailed reference viewed: 10 (0 ULg) Thymic cryptocrine signaling and the immune recognition of self neuroendocrine functionsGeenen, Vincent ; Martens, Henri ; et alin Progress in NeuroEndocrinImmunology (1991), 4 Detailed reference viewed: 3 (2 ULg) The Photoionization of Ammonia revisited. The Vibrational Autoionization of NH3 and its three Isotopomers in the 10-12 eV photon energy range.Locht, Robert ; Leyh, Bernard ; et alin Chemical Physics (1991), 155 The photoionzation efficiency curves of NH3 and its three isotopomers have been investigated in the photon energy range of the first ionized state. From the analysis of the corresponding vibrational ... [more ▼] The photoionzation efficiency curves of NH3 and its three isotopomers have been investigated in the photon energy range of the first ionized state. From the analysis of the corresponding vibrational structure, wavenumbers and anharmonicity constants are deduced. The detailed investigation of the abundant autoionization structure tends to show the adiabatic ionization energy to be 10.072+/-0.010 eV for NH3, NH2D and NHD2 and 10.083+/-0.010 eV for ND3. All autoionization features were classified in vibrational progressions (nu2 bending mode) belonging to nasa1 (or nd) and npe (n=5, 6, 7) Rydberg series. Vibrational autoionization occurs through Delta v transitions up to -9. A qualitative analysis of the intensity distribution of these series strongly supports that transitions involving odd Delta v values are favoured. This observation can be understood by applying group theoretical considerations to the theory of vibrational autoionization. [less ▲] Detailed reference viewed: 38 (14 ULg) Determination of Thiamin and Its Phosphate Esters in Cultured Neurons and Astrocytes Using an Ion-Pair Reversed-Phase High-Performance Liquid Chromatographic MethodBettendorff, Lucien ; ; Jouan, Caroline et alin Analytical Biochemistry (1991), 198(1), 52-59 A sensitive method, based on fluorescence detection, for the determination of thiamin derivatives after precolumn derivatization is described. The separation is achieved on a PRP-1 column using ion-pair ... [more ▼] A sensitive method, based on fluorescence detection, for the determination of thiamin derivatives after precolumn derivatization is described. The separation is achieved on a PRP-1 column using ion-pair reversed-phase HPLC. This method is especially well adapted to the detection of thiamin triphosphate in complex mixtures such as tissue extracts. The detection limit for TTP is 50 fmol. The contents of thiamin derivatives were determined in primary cultures of rat cerebellar granule neurons and cerebral astrocytes. The amount of TTP is about five times higher in neurons than in astrocytes. Thus in rat brain TTP seems to be essentially associated with neurons and the intracellular concentration is estimated to be about 0.2 microM. Our results suggest the existence, in nerve cells, of specific regulatory mechanisms not related to the blood-brain barrier and responsible for the maintenance of thiamin homeostasis in brain. [less ▲] Detailed reference viewed: 24 (9 ULg) Neuroendocrine Control of the Onset of Puberty: Secretion of Gonadotrophin-Releasing Hormone from Rat Hypothalamic ExplantsBourguignon, Jean-Pierre ; Gerard, Arlette ; et alin Acta Paediatrica Scandinavica. Supplement (1991), 372 Detailed reference viewed: 17 (0 ULg) MR1125988,Salmenjoki, Kimmo ,On numerical methods for shape design problemsRochus, Pierre ![]() in Mathematical Reviews [=MR] (1991) Detailed reference viewed: 9 (0 ULg) Aspects chirurgicaux du traitement des affections surrenaliennes.Meurisse, Michel ; ; et alin Acta Chirurgica Belgica (1991), 91(2), 107-11 With the greatly enhanced accuracy of current endocrinologic diagnosis assisted by precise diagnostic imaging, together with greatly enhanced preparation of patients with endocrinopathy for safer ... [more ▼] With the greatly enhanced accuracy of current endocrinologic diagnosis assisted by precise diagnostic imaging, together with greatly enhanced preparation of patients with endocrinopathy for safer anesthetic and surgical procedure (e.g. adrenal cortical cancers, cortisol and aldosterone producing adenomas and pheochromocytomas), operative procedures can be planned and conducted more precisely. For the surgeon, the strategy for treatment of functional and neoplastic disorders of the adrenal glands has essentially to consider the anatomy of the suprarenal glands, the deleterious effects of hormone excess before and during operation, the presumed nature of incidentally discovered adrenal mass and the size of the tumor. [less ▲] Detailed reference viewed: 12 (0 ULg) Métoda Marginilor RigidizateRigo, Philippe ; in Studii şi Cercetări de Mecanică Aplicată (1991) Detailed reference viewed: 25 (0 ULg) Recension bibliographique de "Plisnier P.D., Micha J.C. et Frank V. : Biologie et exploitation des poissons du Lac Ihema (bassin Akagera, Rwanda)".Poncin, Pascal ; in Cahiers d'Ethologie (1991), 11(4), 522 Detailed reference viewed: 4 (0 ULg) Compte rendu de A. Stückelberger, Einführung in der antiken Naturwissenschaft, Darmstadt, 1988Marganne, Marie-Hélène ![]() in Archives Internationales d'Histoire des Sciences (1991), 41 Detailed reference viewed: 4 (0 ULg) Spatially continuous processing within a raster based GIS : some examples of geographical modelsDonnay, Jean-Paul ; Binard, Marc ![]() in Bulletin de la Société belge de Géographie - SOBEG (1991), 2 La représentation d'un territoire en mode raster introduit une discrétisation qui peut être considérée, en première approximation, comme le résultat d'un échantillonnage à deux dimensions de cette surface ... [more ▼] La représentation d'un territoire en mode raster introduit une discrétisation qui peut être considérée, en première approximation, comme le résultat d'un échantillonnage à deux dimensions de cette surface. Sous cette forme, un attribut spatialement continu constitue une couche de données directement accessible aux systèmes d'information géographique (S.I.G.) hybrides (raster/vecteur). Les avantages de cette représentation sont déjà exploités pour visualiser et traiter des phénomènes physiques surfaciques, tels que les modèles numériques de terrain. Une procédure identique peut être appliquée aux surfaces théoriques issues de l'application de modèles géographiques. En outre, les propriétés du mode raster sont susceptibles d'offrir des solutions graphiques soit plus simples, soit en l'absence de solutions analytiques. Cet article illustre ces avantages sur quelques modèles bien connus de l'analyse spatiale. [less ▲] Detailed reference viewed: 27 (5 ULg) Conformational analysis of beta and gamma lactam antibiotics; Dive, Georges ; Ghuysen, Jean-Marie ![]() in European Journal of Medicinal Chemistry (1991), 26(1), 43-50 Geometry optimization, superimposition searches and conformational analysis carried on several lactam antibiotics show that reactivity with the active-site serine penicillin-binding proteins is related to ... [more ▼] Geometry optimization, superimposition searches and conformational analysis carried on several lactam antibiotics show that reactivity with the active-site serine penicillin-binding proteins is related to a particular spatial disposition of 2 flanking functional groups - namely a C = O or C-OH on 1 side and a carboxylate on the other - with respect to the central scissile amide bond. Such a binding entity is found in one of the most stable conformers of the tripeptide diacetyl-L-Lys-D-Ala-D-Ala conferring substrate activity, and in benzylpenicillin, cephapyrin, thienamycin, gamma-lactam, the 6-spiro-epoxypenicillin S and in one epimer of lactivicin, conferring inactivating potency. This binding entity generates a particular electronic distribution and the fact that it is conserved in compounds belonging to very different chemical families strongly suggests that it is an important feature required for enzyme recognition. [less ▲] Detailed reference viewed: 37 (1 ULg) Pulsatile insulin delivery has greater metabolic effects than continuous hormone administration in man: importance of pulse frequency.; Scheen, André ; et alin Journal of Clinical Endocrinology and Metabolism (1991), 72(3), 607-15 The aim of this study was to see if the greater effect of insulin on hepatic glucose output when insulin is given using 13-min pulses in man remains when the same amount of insulin is delivered using 26 ... [more ▼] The aim of this study was to see if the greater effect of insulin on hepatic glucose output when insulin is given using 13-min pulses in man remains when the same amount of insulin is delivered using 26-min pulses. The study was performed on nine male healthy volunteers submitted to a 325 min glucose-controlled glucose iv infusion using the Biostator. The endogenous secretion of pancreatic hormones was inhibited by somatostatin. Three experiments were performed in each subject on different days and in random order. In all cases glucagon was replaced (58 ng min-1). The amounts of insulin infused were identical in all instances and were 0.2 mU kg-1 min-1 (continuous), 1.3 mU kg-1 min-1, 2 min on and 11 min off (13-min pulses) or 2.6 mU kg-1 min-1, 2 min on and 24 min off (26-min pulses). Blood glucose levels and glucose infusion rate were monitored continuously by the Biostator, and classic methodology using D-[3-3H] glucose infusion allowed to study glucose turnover. When compared with continuous insulin, 13-min insulin pulses induced a significantly greater inhibition of endogenous glucose production. This effect disappeared when insulin was delivered in 26-min pulses. We conclude that, in man, an adequate pulse frequency is required to allow the appearance of the greater inhibition of pulsatile insulin on endogenous glucose production. [less ▲] Detailed reference viewed: 11 (0 ULg) Starters pour la charcuterie; ; Thonart, Philippe ![]() in Viande et Bien-être = Vlees en Welzijn (1991), (2), 3-7 Detailed reference viewed: 5 (1 ULg) Evidence that the interaction between circulating IgA and fibronectin is a normal process enhanced in primary IgA nephropathy.; ; et al in Journal of Clinical Immunology (1991), 11(2), 78-94 A solid-phase ELISA was set up to measure the direct binding capacity (BC) of different, commercially available, purified human IgA preparations to plates coated with human fibronectin (FN). It was found ... [more ▼] A solid-phase ELISA was set up to measure the direct binding capacity (BC) of different, commercially available, purified human IgA preparations to plates coated with human fibronectin (FN). It was found that secretory, polymeric, and, to a much lesser extent, monomeric IgA exhibited elevated FN-BC as compared to their BC to plates coated with bovine serum albumin. This binding was specific since not observed with human IgG or IgM antibodies. In addition, we noted that this interaction was dose dependent, Ca2+ dependent, saturable, and not covalent, was inhibited by soluble FN, but not by a prior incubation of FN-coated plates with anti-human fibronectin antibodies, and appeared to involve on the dimeric FN other structures than its heparin-binding, collagen-binding, or C1q-binding domains. Similar experiments conducted with normal plasma indicated that plasma IgA, but not plasma IgG or IgM, was also capable of significant binding to FN-coated plates. In contrast, serum IgA did not significantly bind to those plates under otherwise identical experimental conditions. Thus, the coagulation process induces a strong decrease in the FN-BC of circulating IgA, which implies the necessity of using plasma rather than serum to study such interactions. The apparent molecular weight of plasma IgA interacting with FN-coated plates ranged between 450 and 900 kd, and its major binding characteristics were quite similar to those observed with purified polymeric IgA. The FN-BC of plasma IgA was then measured by the same ELISA in 30 patients with primary IgA nephropathy (IgAN) and in 23 healthy controls. The mean FN-BC of plasma IgA was significantly higher in patients than in normal controls. This enhancement was due mainly to the augmentation in the concentration of circulating "macromolecular" IgA and was significantly correlated with the plasma levels of IgA-FN complexes. However, the pathogenetic role of these findings was probably not determinant since similar observations were made in alcoholic liver cirrhosis without urinary abnormalities and since the FN-BC of plasma IgA or the plasma levels of IgA-FN complexes were not correlated with the various biological parameters of evolutivity of primary IgAN. In conclusion, these studies suggest that the ability of polymeric IgA to directly bind to FN is involved in the formation of circulating IgA-FN complexes and that this normal binding process, although enhanced in IgAN, is probably not responsible for kidney injury, at least in the patients studied. [less ▲] Detailed reference viewed: 7 (0 ULg) Les applications informatiques des années 90 et leurs implications sur les réseaux de communicationLeduc, Guy ![]() in Bulletin Scientifique de l'Association des Ingénieurs Electriciens sortis de l'Institut Electrotechnique Montefiore (1991), 2 Detailed reference viewed: 12 (2 ULg) Les inventaires forestiers nationaux en Europe: tentative de synthèse.; Rondeux, Jacques ![]() in Silva Belgica (1991), 98(4), 13-19 Dans de nombreux pays, la forêt est une ressource naturelle importante et au niveau mondial, les problèmes d'approvisionnement en bois se posent avec de plus en plus d'acuité. Le développement des ... [more ▼] Dans de nombreux pays, la forêt est une ressource naturelle importante et au niveau mondial, les problèmes d'approvisionnement en bois se posent avec de plus en plus d'acuité. Le développement des populations et de leurs besoins en bois a fait prendre conscience de la nécessité de gérer ce patrimoine de façon responsable, sous peine de le voir s'appauvrir, voire même disparaître dans des proportions inquiétantes. Assez paradoxalement, ce sont les pays riches en "or vert" qui ont innové dans ce domaine (Suède, Finlande, Canada,...). Mais comment gérer une ressource aussi étendue et diversifiée sans se doter des moyens de la connaître ? A ce titre, un inventaire réalisé à l'échelle des nations est devenu indispensable. Dans les lignes qui suivent, nous tenterons de faire le point sur les approches méthodologiques propres aux inventaires forestiers nationaux (ou régionaux) et nous évoquerons différentes réalisations concrètes actuellement en vigueur dans plusieurs pays, principalement ceux à tradition forestière. [less ▲] Detailed reference viewed: 9 (3 ULg) Traitement des canaux carpiens modérés par le port nocturne d'une orthèse antébrachialeWANG, François-Charles ; ; FOIDART, Marguerite et alin Acta Physiotherapica et Rheumatologica Belgica (1991) Detailed reference viewed: 8 (1 ULg) Laparoscopic management of large ovarian endometrial cyst: use of fibrin sealant.; NISOLLE, Michelle ![]() in Journal of Gynecologic Surgery (1991), 7(3), 163-6 In order to prevent postoperative adhesions often present after CO 2 laser vaporization of large endometriomas, 62 patients with endometriomas greater than 3 cm diameter were treated with a new procedure ... [more ▼] In order to prevent postoperative adhesions often present after CO 2 laser vaporization of large endometriomas, 62 patients with endometriomas greater than 3 cm diameter were treated with a new procedure. Partial cystectomy was performed using the CO 2 laser. Residual endometrial cyst was then vaporized. After laparoscopic vaporization of the interior cyst wall, a fibrin glue (Tissucol) was injected onto the vaporized area to close laparoscopically the ovarian cyst cavity. When performed, second-look laparoscopy demonstrated healing of the ovary without any periovarian adhesions. The incidence of periovarian adhesions was significantly lower (p less than 0.01) than in the group of women treated by laparoscopy and in whom the glue was not used to close the ovarian cyst cavity. [less ▲] Detailed reference viewed: 3 (0 ULg) Maladie de Crohn : de l'immunopathologie aux perspectives thérapeutiquesLouis, Edouard ; Belaiche, Jacques ![]() in Médecine et Hygiène (1991), 49 Detailed reference viewed: 32 (0 ULg) Management of small woods in Belgium.Rondeux, Jacques ![]() in Quarterly Journal of Forestry (1991), 85(1), 37-42 In Belgium, forest occupies 20 per cent of the total land area. Private forests account for about 52 per cent; they are generally small (averaging about three ha) and their owners are not accustomed to ... [more ▼] In Belgium, forest occupies 20 per cent of the total land area. Private forests account for about 52 per cent; they are generally small (averaging about three ha) and their owners are not accustomed to basing their decisions on a management plan. However, some attempts to develop co-operation through forestry associations exist and the regional authorities tend to encourage them. Whatever the details of any possible future legislation may be, the principal aim must be the development and introduction of an extremely simple form of management plan (the so-called 'plan simple de gestion') in exchange for assistance to the private owner. [less ▲] Detailed reference viewed: 6 (1 ULg) Les inventaires forestiers nationaux en Europe: tentative de synthese.; Rondeux, Jacques ![]() in Silva Belgica (1991), 98(6), 41-50 Detailed reference viewed: 11 (6 ULg) Soya oil in diet for growing fattening bulls : effects on animal performance and fatty acid compositionClinquart, Antoine ; Istasse, Louis ; Van Eenaeme, Christian et alin Animal Production (1991), 53 «Forme dell'identità cavalleresca».Moreno, Paola ![]() in Medioevo Romanzo (1991) Detailed reference viewed: 6 (0 ULg) Analyse du coût d'exploitation des navires sur les voies d'eau intérieuresMarchal, Jean ; in Bulletin de l’Association Internationale Permanente des Congrès de Navigation [Bulletin de l'AIPCN] (1991), (supplément au Bulletin n°74), 20 Detailed reference viewed: 27 (12 ULg) Relations d'implémentation et transformations autorisées d'une spécification LOTOSLeduc, Guy ![]() in Réseaux et Informatique Répartie (1991), 1 Detailed reference viewed: 8 (1 ULg) Aller en pèlerinage à Saint-Martin de Tours au XVIIIe siècleGeorge, Philippe ![]() in Bulletin de la Société Royale Le Vieux-Liège (1991), t. XII, n° 261 Detailed reference viewed: 3 (0 ULg) Serine Beta-Lactamases and Penicillin-Binding ProteinsGhuysen, Jean-Marie ![]() in Annual Review of Microbiology (1991), 45 Detailed reference viewed: 23 (0 ULg) Nutritive-Value Of Triticale Cultivars In Pigs As A Function Of Their Chemical-Composition; ; Thewis, André ![]() in Animal Feed Science & Technology (1991), 35(1-2), 49-53 Detailed reference viewed: 6 (0 ULg) Use Of Synthetic Peptides To Map Sequential Epitopes Recognized By Monoclonal-Antibodies On The Bovine Leukemia-Virus External Glycoprotein; ; et al in Virology (1991), 185(1), Detailed reference viewed: 4 (0 ULg) Approche physique des phénomènes hydrodynamiquesMarchal, Jean ![]() in Revue de l'AIRH (1991) Detailed reference viewed: 5 (1 ULg) Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats.Lemaire, Christian ; ; et alin Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1991), 32(12), 2266-72 No-carrier-added [18F]altanserin was synthesized by nucleophilic substitution of the corresponding nitro compound with [18F]fluoride in the presence of kryptofix 222 and K2CO3. After purification by ... [more ▼] No-carrier-added [18F]altanserin was synthesized by nucleophilic substitution of the corresponding nitro compound with [18F]fluoride in the presence of kryptofix 222 and K2CO3. After purification by preparative HPLC, [18F]altanserin was produced in less than 2 hr with a radiochemical yield of 10% (EOS) and a specific activity of 0.8-1.3 Ci/mumol. In rats, the tracer localized rapidly in the whole brain (0.5% ID/g organ) with a high binding to the frontal cortex. The frontal cortex/cerebellum ratio increased with time and reached a plateau of 11 at 2 hr postinjection. This uptake in S2 receptor regions was saturable and could be blocked by pretreatment with various S2 antagonists. This radiopharmaceutical appears to be more selective for S2 receptor sites than other ligands available today and allows the study of S2 receptors under in vivo conditions. [less ▲] Detailed reference viewed: 12 (4 ULg) Les courants excito moteurs de basses fréquences. Détermination des durées d'impulsions optimales de stimulationVanderthommen, Marc ; ; Crielaard, Jean-Michel ![]() in Kinésitherapie, les Annales (1991), 18(10), 483-484 Detailed reference viewed: 4 (2 ULg) Compte-rendu de WillibrordGeorge, Philippe ![]() in Moyen Age (Le) (1991) Detailed reference viewed: 4 (0 ULg) Miscellaneous spectroscopic observations of quasars and quasar candidates; ; et al in Astronomy and Astrophysics. Supplement Series (1990), 86 Spectroscopic observations are presented for 11 quasar candidates, as well as 19 quasars with uncertain redshift, three BL Lac candidates, and 11 objects located within a few arcsec of a quasar. The ... [more ▼] Spectroscopic observations are presented for 11 quasar candidates, as well as 19 quasars with uncertain redshift, three BL Lac candidates, and 11 objects located within a few arcsec of a quasar. The spectra indicate than nine of the 11 quasar candidates are stars, while the remaining two are low-redshift galaxies. The individual objects studied and commented on include KPNO 1, CFHT 2, Q 0010+023, UM 232, UM 473, WEE 124, UM 644, PKS 1514+197, MC3 1639+155, and WEE 185. [less ▲] Detailed reference viewed: 6 (1 ULg) Catalogue of Lambda Bootis CandidatesRenson, Pierre ; ; in Bulletin d'Information du Centre de Données Stellaires (1990), 38 Not Available Detailed reference viewed: 5 (1 ULg) Characterization of an Enterococcus Hirae Penicillin-Binding Protein 3 with Low Penicillin Affinity; ; et al in Journal of Bacteriology (1990), 172(12), 6856-6862 Enterococcus hirae S185, a clinical isolate from swine intestine, exhibits a relatively high resistance to penicillin and contains two 77-kDa penicillin-binding proteins 3 of high (PBP 3s) and low (PBP 3r ... [more ▼] Enterococcus hirae S185, a clinical isolate from swine intestine, exhibits a relatively high resistance to penicillin and contains two 77-kDa penicillin-binding proteins 3 of high (PBP 3s) and low (PBP 3r) affinity to penicillin, respectively. A laboratory mutant S185r has been obtained which overproduces PBP 3r and has a highly increased resistance to penicillin. Peptide fragments specifically produced by trypsin and SV8 protease digestions of PBP 3r were isolated, and the amino acid sequences of their amino terminal regions were determined. On the basis of these sequences, oligonucleotides were synthesized and used as primers to generate, by polymerization chain reaction, a 233-bp DNA fragment the sequence of which translated into a 73-amino-acid peptide segment of PBP 3r. These structural data led to the conclusion that the E. hirae PBP 3r and the methicillin-resistant staphylococcal PBP 2' are members of the same class of high-Mr PBPs. As shown by immunological tests, PBP 3r is not related to PBP 3s but, in contrast, is related to the 71-kDa PBP 5 of low penicillin affinity which is responsible for penicillin resistance in E. hirae ATCC 9790 and R40. [less ▲] Detailed reference viewed: 9 (3 ULg) Liste des étoiles Ap et Am dans les amas ouverts (Edition révisée)Renson, Pierre ![]() in Bulletin d'Information du Centre de Données Stellaires (1990), 38 We give a revised, and more complete, version of the "Catalogue of Ap and Am stars in open clusters given elsewhere (Renson, 1988a). Detailed reference viewed: 4 (0 ULg) Perspectives à l'horizon 1992 de la mobilité des biens et des personnes dans la CEE. Conclusions du congrès "Transports à l'Horizon 1992" GTU-AILMarchal, Jean ![]() in Bulletin de l'AILG (1990), (12), 3 Detailed reference viewed: 6 (2 ULg) An automatic remeshing processorHabraken, Anne ![]() in Journal of Materials Processing Technology (1990), 24 Detailed reference viewed: 7 (2 ULg) Effects of the Nonsteroidal Inhibitor R76713 on Testosterone-Induced Sexual Behavior in the Japanese Quail (Coturnix Coturnix Japonica)Balthazart, Jacques ; ; in Hormones & Behavior (1990), 24(4), 510-31 A new triazole derivative, R76713 (6-[4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H- benzotriazole), was recently shown to inhibit aromatase selectively without affecting other steroid ... [more ▼] A new triazole derivative, R76713 (6-[4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl]-1-methyl-1H- benzotriazole), was recently shown to inhibit aromatase selectively without affecting other steroid-metabolizing enzymes and without interacting with estrogen, progestin, or androgen receptors. This compound was tested for its capacity to intefere with the induction of copulatory behavior by testosterone (T) in castrated Japanese quail (Coturnix coturnix japonica). In a first experiment, R76713 inhibited (range 0.01 to 1 mg/kg) the activation of sexual behavior by T silastic implants and hypothalamic aromatase activity in castrated male quail in a dose-dependent manner. The 5 alpha- and 5 beta- reductases of T were not systematically affected. Stereotaxic implantation of R76713 in the medial preoptic area similarly blocked the behavior activated by systemic treatment with T, demonstrating that central aromatization of androgen is implicated in the activation of behavior. These inhibiting effects of R76713 on behavior were observed when implants were placed in the medial part of the nucleus preopticus medialis, confirming the implication of this brain area in the control of male copulatory behavior. Finally, the behavioral inhibition produced by R76713 could be reversed by simultaneous treatment with a dose of estradiol, which was not behaviorally effective by itself. This suggests that the behavioral deficit induced by the inhibitor was specifically due to the suppression of estrogen production. This also shows that the activation of copulatory behavior probably results from the interaction of androgens and estrogens at the brain level, as the two treatments separately providing these hormonal stimuli (T with the aromatase inhibitor on one hand and a low dose of estradiol on the other hand) had almost no behavioral effects but they synergized to activate copulation when given concurrently. These data confirm the critical role of preoptic aromatase in the activation of reproductive behavior and demonstrate that R76713 is a useful tool for the in vivo study of estrogen-dependent processes. [less ▲] Detailed reference viewed: 9 (1 ULg) Plasma renin activity and urine beta 2-microglobulin during and after cardiopulmonary bypass: pulsatile vs non-pulsatile perfusionCanivet, Jean-Luc ; Larbuisson, Robert ; Damas, Pierre et alin European Heart Journal (1990), 11(12), 1079-1082 Fourteen patients with normal preoperative renal function underwent aortocoronary bypass graft using cardiopulmonary bypass (CPB) with pulsatile (P;n = 7) or non pulsatile (NP;n = 7) perfusion. In the two ... [more ▼] Fourteen patients with normal preoperative renal function underwent aortocoronary bypass graft using cardiopulmonary bypass (CPB) with pulsatile (P;n = 7) or non pulsatile (NP;n = 7) perfusion. In the two groups prebypass values of plasma renin activity (PRA) and urine beta 2-microglobulin (beta 2-M) were within normal limits. PRA increased significantly during CPB and the first 6 h after CPB only in the non-pulsatile group. In both groups, the urine beta 2-M level increased significantly during and after CPB; however, there was no significant difference in urine beta 2-M levels between the two groups. Also, the amount of beta 2-M excreted in urines per unit of time increased significantly in both groups during and after CPB; there was no significant difference between the two groups. [less ▲] Detailed reference viewed: 20 (1 ULg) Heparin-induced thrombocytopenia: A case reportVan Damme, Hendrik ; Damas, Pierre ; David, Jean-Louis et alin Angiology (1990), 41(12), 1075-1081 The authors report a case of heparin-induced thrombocytopenia, in whom massive pulmonary embolism occurred in spite of heparin anticoagulation. Successful pulmonary thrombectomy was carried out under ... [more ▼] The authors report a case of heparin-induced thrombocytopenia, in whom massive pulmonary embolism occurred in spite of heparin anticoagulation. Successful pulmonary thrombectomy was carried out under cardiopulmonary bypass, with limitation of platelet clumping during bypass by aggregation inhibitors. This report is a comprehensive contribution to a better understanding of this rare immunoallergic complication of heparin administration, with a high incidence of serious thromboembolic events. The optimal management for cases of unavoidable reexposure to heparin is discussed. [less ▲] Detailed reference viewed: 11 (1 ULg) Le "Plan d'affaire", premier pas vers une réflexion stratégique pour la petite et moyenne entrepriseVan Caillie, Didier ![]() in La Vie au Bureau (1990), 1990(Décembre), 17-23 This paper discusses the structure and the content of a "Business Plan" when this tool is dedicated to base strategic thinking in a SME Detailed reference viewed: 62 (10 ULg) Diurnal Rhythmicity in the Pattern of Mrnas in the Leaves of Sinapis AlbaCremer, Frédéric ; Dommes, Jacques ; Van de Walle, Claude et alin Plant Physiology (1990), 94(4), 1590-1597 Previous studies have shown that certain specific leaf mRNAs exhibit a diurnal rhythmicity in their quantity in higher plants. To determine whether this situation is restricted to a few mRNAs, or affects ... [more ▼] Previous studies have shown that certain specific leaf mRNAs exhibit a diurnal rhythmicity in their quantity in higher plants. To determine whether this situation is restricted to a few mRNAs, or affects a large number, we have used in vitro translation and two-dimensional polyacrylamide gel electrophoresis to analyze the mRNA complement in leaves of Sinapis alba at different times during an 8-hour/16-hour day/night cycle. A method for the visual analysis of two-dimensional polyacrylamide gel electrophoresis was also developed. This method selected, at each sampling time, spots that were significant. It then selected, between two sampling times, intensity changes that were significant at the 0.02 confidence level. During a day/night cycle, complex rhythmic changes affected about 10% of the mRNAs. Nineteen different rhythm patterns were found. These 19 patterns fell into four main classes: mRNAs that increase during the light period and decrease during the dark, mRNAs that increase and then decrease during the light period, mRNAs that decrease during the light period and increase during the dark period, and mRNAs that increase and then decrease during the dark period. [less ▲] Detailed reference viewed: 1 (1 ULg) Accuracy in Early Prediction of Prognosis of Patients with Septic Shock by Analysis of Simple Indices: Prospective StudyD'Orio, Vincenzo ; ; et alin Critical Care Medicine (1990), 18(12), 1339-45 In 26 consecutive septic shock patients, we analyzed the clinical, hemodynamic, and metabolic data before and during volume infusion to test their circulatory reserve in response to fluid repletion. These ... [more ▼] In 26 consecutive septic shock patients, we analyzed the clinical, hemodynamic, and metabolic data before and during volume infusion to test their circulatory reserve in response to fluid repletion. These patients were investigated to identify early variables that could predict outcome. There were 15 survivors (group A) and 11 nonsurvivors (group B). As a mean, group A patients were hemodynamically evaluated 2.3 h after onset of the sepsis syndrome, whereas group B patients underwent cardiac catheterization after a 12-h interval. At the initial evaluation, both groups demonstrated similarly decreased mean arterial pressure, mean heart rate, and mean cardiac filling pressure. Only group A patients evidenced elevated cardiac index (CI) (greater than 4 L/min.m2) associated with low systemic vascular resistance index (less than 7400 dyne.sec/cm5.m2), which is generally recognized as hyperdynamic cardiac state. However, none of the initial cardiovascular variables could serve as a predictor for survival. Fluid challenge increased left ventricular preload from 6 to 12.4 and from 7.8 to 12.7 mm Hg in group A and group B, respectively. The increases were associated with significant increases in CI from 4.4 to 6.9 and from 3 to 3.8 L/min.m2. However, at the end of fluid challenge, only group A patients exhibited normal cardiac response, as evidenced by the change in left ventricular stroke work index (LVSWI) for a given increase in the pulmonary capillary wedge pressure (WP) that was referred to as left cardiac preload.(ABSTRACT TRUNCATED AT 250 WORDS) [less ▲] Detailed reference viewed: 16 (1 ULg) An automatic remeshing technique for finite element simulation of forming processesHabraken, Anne ; Cescotto, Serge ![]() in International Journal for Numerical Methods in Engineering (1990), 30(8), 1503-1525 Detailed reference viewed: 29 (8 ULg) Reconstituted Basement Membrane Matrix Stimulates Interstitial Procollagenase Synthesis by Human Fibroblasts in Culture; ; Munaut, Carine et alin Matrix (Stuttgart, Germany) (1990), 10(6), 373-7 Synthesis of interstitial collagenase by human fibroblasts was compared when cultured on plastic, in the presence or absence of soluble laminin, on a type I collagen gel and on a gel of basement membrane ... [more ▼] Synthesis of interstitial collagenase by human fibroblasts was compared when cultured on plastic, in the presence or absence of soluble laminin, on a type I collagen gel and on a gel of basement membrane components (matrigel). Fibroblasts cultured on matrigel or on type I collagen gel displayed an increase in the steady-state levels of mRNA for interstitial procollagenase that was proportional to its enzymatic activity. Laminin, the main component of matrigel, had no effect on the interstitial collagenase synthesis by fibroblasts. We suggest that matrigel, which stimulates the interstitial collagenase production at a transcriptional step, could regulate the catabolic potential of fibroblasts. [less ▲] Detailed reference viewed: 6 (1 ULg) Indications actuelles de la greffe hétérotopique en transplantation cardiaqueRADERMECKER, Marc ; Defraigne, Jean-Olivier ; Limet, Raymond ![]() in Revue Médicale de Liège (1990), 45(12), 614-9 Detailed reference viewed: 7 (0 ULg) Response to Epidermal Growth Factor of Skin Fibroblasts from Donors of Varying Age Is Modulated by the Extracellular MatrixColige, Alain ; Nusgens, Betty ; in Journal of Cellular Physiology (1990), 145(3), 450-7 The present study was undertaken to investigate the effect of epidermal growth factor (EGF) on the biosynthetic activity of skin fibroblasts from donors of varying age and the modulation of their response ... [more ▼] The present study was undertaken to investigate the effect of epidermal growth factor (EGF) on the biosynthetic activity of skin fibroblasts from donors of varying age and the modulation of their response to this growth factor by culture in a three-dimensional extracellular matrix. When cultured in monolayer on plastic or at the surface of a collagen gel, EGF specifically inhibited collagen synthesis whatever the age of the donor (from 17 to 84 years, n = 11). This inhibition was paralleled by a significant decrease in the steady-state level of procollagen type I mRNAs. When embedded in a three-dimensional floating collagen lattice, EGF stimulated the non-collagen protein (NCP) synthesis in fibroblasts from younger donors (5 out of 6) while fibroblasts from the older ones were not affected. Collagen production by fibroblasts from younger donors was not inhibited as in monolayer (some being even stimulated) while that of the older donors was inhibited as observed in monolayer. The steady-state level of procollagen type I mRNA was not modified by EGF in the three-dimensional culture. No significant difference was observed in the affinity and the number of EGF receptors of the fibroblasts on plastic or embedded in a collagen lattice between young and aged donors. Our results suggest that the environment of the cells can modulate the reactivity to EGF and reveal differences related to in vivo aging. [less ▲] Detailed reference viewed: 42 (6 ULg) Pour une production ligneuse de qualité : impératifs écologiques et sylvicoles.; ; Rondeux, Jacques ![]() in Agricontact (1990), (223), 1-7 Detailed reference viewed: 4 (1 ULg) Malouf's Great DivideDelrez, Marc ![]() in Australian Book Review (1990), (127), 1743 Detailed reference viewed: 21 (3 ULg) New observations and gravitational lens models of the Cloverleaf quasar H1413 + 117; Surdej, Jean ; et alin Astrophysical Journal (1990), 364 New optical and radio observations of the quadruple quasar H1413 + 117, the Cloverleaf, are presented. VLA data show radio counterparts at the positions of the four optical images and an additional strong ... [more ▼] New optical and radio observations of the quadruple quasar H1413 + 117, the Cloverleaf, are presented. VLA data show radio counterparts at the positions of the four optical images and an additional strong radio source between images B and D. Gravitational lens models of H1413 + 117 using (1) a single elliptical galaxy and (2) two spherical galaxies are presented, which fit the positions of the four images of the quasar remarkably well. The models suggest that the strong radio source is a feature of the quasar, e.g., an ejected blob, which lies right on the caustic of the lens and is thereby strongly amplified. The time delays predicted by these models are sufficiently short to allow for their determination within one observational season, making H1413 + 117 an exceptionally well suited object for gravitational lens research. [less ▲] Detailed reference viewed: 8 (4 ULg) Sequence of a Lipase Gene from the Antarctic Psychrotroph Moraxella Ta144Feller, Georges ; ; Gerday, Charles ![]() in Nucleic Acids Research (1990), 18(21), 6431 Detailed reference viewed: 4 (0 ULg) Distribution of Aromatase in the Brain of the Japanese Quail, Ring Dove, and Zebra Finch: An Immunocytochemical StudyBalthazart, Jacques ; Foidart, Agnès ; et alin Journal of Comparative Neurology (1990), 301(2), 276-88 An immunocytochemical peroxidase-antiperoxidase procedure using a purified polyclonal antibody raised against human placental aromatase was used to localize aromatase-containing cells in the brain of ... [more ▼] An immunocytochemical peroxidase-antiperoxidase procedure using a purified polyclonal antibody raised against human placental aromatase was used to localize aromatase-containing cells in the brain of three avian species: the Japanese quail, the ring dove, and the zebra finch. In quail and dove, immunoreactive cells were found only in the preoptic area and hypothalamus, with a high density of positive cells being present in the medial preoptic area, in the septal area above the anterior commissure, in the ventromedial nucleus of the hypothalamus, and in rostral part of the infundibulum. Immunoreactivity was weaker in zebra finches, and no signal could therefore be detected in the ventromedial and tuberal hypothalamus. The positive material was localized in the perikarya and in adjacent cytoplasmic processes, including the full length of axons always leaving a clear unstained cell nucleus. These features could be observed in more detail on sections cut from perfused brains and stained with an alkaline phosphatase procedure. The distribution of aromatase immunoreactivity was similar in the three species although minor differences were observed in the preoptic area. The localization of labelled neurons coincided with the distribution of aromatase activity as studied by in vitro radioenzyme assays on brain nuclei dissected by the Palkovits punch method. There was one striking exception to this rule: no immunoreactivity was detected in the zebra finch telencephalon, while assays had shown the presence of an active enzyme in several nuclei such as the robustus archistriatalis, the hyperstriatum ventrale pars caudale, and the hippocampus and area parahippocampalis. The origins of this discrepancy and the functional role of the aromatase observed in the axons are discussed. [less ▲] Detailed reference viewed: 4 (1 ULg) Manipulation photopériodique des saisons de reproduction chez le barbeau (Barbus barbus)Poncin, Pascal ; in Cahiers d'Ethologie (1990), 10(3-4), 447-450 Pendant deux ans nous avons soumis quatre lots expérimentaux de barbeaux mâles et femelles d'élevage à différentes photopériodes artificielles, permettant une production quasi continue de larves. Celles ... [more ▼] Pendant deux ans nous avons soumis quatre lots expérimentaux de barbeaux mâles et femelles d'élevage à différentes photopériodes artificielles, permettant une production quasi continue de larves. Celles-ci ont été élevées en eau réchauffée et utilisées pour l'expérimentation en génétique, le repeuplement des rivières et la commercialisation. [less ▲] Detailed reference viewed: 26 (4 ULg) Core velocity dispersion and mass-to-light ratio of the old Magellanic globular cluster NGC 1835; ; et al in Astronomy and Astrophysics (1990), 239 Abstract image available at: http://adsabs.harvard.edu/abs/1990A&A...239..142D Detailed reference viewed: 7 (1 ULg) The latitudinal gradient of the NO peak density; ; Gérard, Jean-Claude ![]() in Journal of Geophysical Research (1990), 95 Results are presented from SME observations of the latitudinal gradients of peak NO densities at about 110-km altitude during the solstice and equinox periods from 1982 through 1985. It is shown that the ... [more ▼] Results are presented from SME observations of the latitudinal gradients of peak NO densities at about 110-km altitude during the solstice and equinox periods from 1982 through 1985. It is shown that the response of the peak NO densities to the declining level of solar activity varies with latitude, with the polar regions exhibiting low sensitivity and the low-latitude regions responding strongly. The SME data also revealed marked asymmetries in the latitudinal structure of the two hemispheres for each season and considerable day-to-day variations in the NO densities. The solar cycle minimum data for June were simulated using a two-dimensional model; results of sensitivity studies performed with varied quenching rate and eddy diffusion coefficient are presented. [less ▲] Detailed reference viewed: 8 (0 ULg) Beta-lactamase expression in Streptomyces cacaoi; ; et al in Journal of Bacteriology (1990), 172(11), 6427-6434 Plasmids were prepared by inserting genomic DNA fragments from Streptomyces cacaoi within the mel gene of plasmid pIJ702. The inserted DNA fragments contain the beta-lactamase-encoding bla gene and ... [more ▼] Plasmids were prepared by inserting genomic DNA fragments from Streptomyces cacaoi within the mel gene of plasmid pIJ702. The inserted DNA fragments contain the beta-lactamase-encoding bla gene and upstream nucleotide sequences of various lengths. The transcription start point of bla was identified by nuclease S1 mapping. Upstream nucleotide sequences of sufficient lengths had an enhancing effect on beta-lactamase production by the Streptomyces host. The dot blot hybridization assay revealed that this effect was exerted at the transcriptional level. Experimental evidence strongly suggests that the underlying mechanism involves, at least in part, one or several trans-acting elements. In one of the constructs, in which the upstream nucleotide sequence was reduced to 0.3 kb, the bla promoter was present but the bla gene was expressed by readthrough from a promoter, possibly the mel promoter, of the pIJ702 vector. [less ▲] Detailed reference viewed: 8 (3 ULg) The chemical composition of the extreme halo stars. II - Green spectra of 20 dwarfs; Magain, Pierre ![]() in Astronomy and Astrophysics (1990), 238 The abundances of nine elements in the atmospheres of 20 extreme metal-poor stars are derived from green spectra obtained with the ESO Cassegrain Echelle Spectrograph (CASPEC). Sodium is found to be ... [more ▼] The abundances of nine elements in the atmospheres of 20 extreme metal-poor stars are derived from green spectra obtained with the ESO Cassegrain Echelle Spectrograph (CASPEC). Sodium is found to be overabundant with respect to aluminum by as much as one dex. There is some scatter in Ca/Fe which cannot be accounted for by random errors in equivalent widths or atmospheric parameters. Scandium is overabundant relative to iron. Some barium lines may be affected by strong departures from local thermodynamic equilibrium. The nitrogen-rich metal-poor star HD 74000, which was found in previous work to be also Al-rich, also presents higher than usual abundances of Na and of s-process elements. It can thus be considered as a mild barium dwarf of Population II. [less ▲] Detailed reference viewed: 9 (1 ULg) The chemical composition of the extreme halo stars. III - Equivalent widths of 20 dwarfs; Magain, Pierre ![]() in Astronomy and Astrophysics. Supplement Series (1990), 86 In the first two papers of this series the chemical composition of 20 extreme halo stars was discussed. The abundances of a number of elements were determined using model atmosphere analysis of equivalent ... [more ▼] In the first two papers of this series the chemical composition of 20 extreme halo stars was discussed. The abundances of a number of elements were determined using model atmosphere analysis of equivalent widths. In this paper a tabulation of the equivalent width data is presented. A comparison of the measurements with the equivalent widths from different sources is used to assess the quality of the data. [less ▲] Detailed reference viewed: 2 (0 ULg) Influence of breed of fetus on periparturient endocrine responses and subsequent milk production of Ayrshire dams; ; Beckers, Jean-François et alin Journal of Dairy Science (1990), 73(10), 2766-2773 Purebred Ayrshire females were assigned to two groups based on the breed of fetus carried during gestation. In group 1, Limousin embryos were transferred nonsurgically into Ayrshire recipients (10 heifers ... [more ▼] Purebred Ayrshire females were assigned to two groups based on the breed of fetus carried during gestation. In group 1, Limousin embryos were transferred nonsurgically into Ayrshire recipients (10 heifers and 1 cow), and in group 2, 11 Ayrshire heifers and 1 cow were inseminated artificially to Ayrshire bulls. Blood samples were collected daily from d 265 of gestation until d 15 postpartum from 5 heifers of each group. Milk yield was recorded on alternate weeks during the first 20 wk postpartum. Calf birth weight was higher (44.2 vs. 35.4 kg) and gestation was longer (297.4 vs. 280.2 d) in Ayrshire dams bearing Limousin fetuses than in those bearing Ayrshire fetuses. Daily milk production for the first 20 wk was lower (18.1 vs. 20.8 kg) in Ayrshire dams bearing Limousin fetuses than in those bearing Ayrshire fetuses. Prepartum decrease in progesterone concentrations and increase in estrone concentrations were faster in Ayrshire heifers bearing Limousin fetuses than in those bearing Ayrshire fetuses. Profiles of peripartum concentrations of bovine placental lactogen differed between Ayrshire dams carrying different families of Limousin fetuses but were similar in those carrying families of Ayrshire fetuses. The concentrations of 15-keto-13,14-dihydroprostaglandin F2 were lower during the postpartum period in heifers that gave birth to Limousin calves than in those that had Ayrshire calves. In conclusion, the breed of fetus influences physiological and endocrine responses of the dam, which might have some effect on milk production of the dam. [less ▲] Detailed reference viewed: 14 (2 ULg) Détermination du degré de réticulation du collagène par sa solubilité thermique et par analyse calorimétrique différentielle (ACD).; Sindic, Marianne ; et alin Viandes et Produits Carnés (1990), 11 Detailed reference viewed: 42 (0 ULg) Le tamoxifene comme premier traitement du cancer du sein chez la femme âgée: un recul de 10 ansColin, Claude ; Lifrange, Eric ; et alin Revue Médicale de Liège (1990), 45(11), 533-8 Cinquante-six patientes, âgées de plus de 70 ans, ont été traitées par tamoxifène pour cancer mammaire T1 à T4. Un délai de 3 à 6 mois est nécessaire pour obtenir une régression de l'opacité tumorale dans ... [more ▼] Cinquante-six patientes, âgées de plus de 70 ans, ont été traitées par tamoxifène pour cancer mammaire T1 à T4. Un délai de 3 à 6 mois est nécessaire pour obtenir une régression de l'opacité tumorale dans 46,4% des cas, une stabilisation dans 30,4% et une augmentation dans 23,2%. Le type de réponse semble indépendant du stade initial de la tumeur. La survie globale à 10 ans n'est pas différente de cette des patientes de même âge qui avaient préféré recourir au traitement loco-régional classique. Par contre, en cas de régression tumorale, la durée de la survie est nettement plus longue et est comparable à celle d'une population témoin de même âge. Les récidives locales sont fréquentes. Elle sont de moins bon pronostic si elles surviennent au cours des trois premières années du traitement. La véritable cause du décès est souvent difficile à préciser chez ces patientes. Une relation directe avec le cancer mammaire n'est observée que dans la moitié des cas. [less ▲] Detailed reference viewed: 71 (9 ULg) De la valeur d'une entreprise à la détermination de son prix de cession : le problème du "Goodwill"Van Caillie, Didier ; in La Vie au Bureau (1990), 1990(Novembre), 12-20 This paper discusses key aspects linked to the valuation of "Goodwill" in the Belgian accounting context and discusses some important questions specific to the valuation of SMEs. Detailed reference viewed: 43 (4 ULg) Androgen and Estrogen Action in the Preoptic Area and Activation of Copulatory Behavior in QuailBalthazart, Jacques ; in Physiology & Behavior (1990), 48(5), 599-609 The sites of androgen and estrogen action on sexual behavior were studied in the preoptic area of castrated male Japanese quail by stereotaxic implantation of hormones, antihormones and metabolism ... [more ▼] The sites of androgen and estrogen action on sexual behavior were studied in the preoptic area of castrated male Japanese quail by stereotaxic implantation of hormones, antihormones and metabolism inhibitors. The first experiment demonstrated that bilateral implantation of the aromatase inhibitor, androstatrienedione (ATD), in the sexually dimorphic nucleus (POM) of the preoptic area can completely suppress the behavioral activation produced by a systemic treatment with testosterone. The effects of ATD were only observed if the implants were located in the POM. In the second experiment, implants in the POM of the synthetic estrogen, diethylstilbestrol, restored copulatory behavior in castrated males while implants of the synthetic nonaromatizable androgen, methyltrienolone, were almost ineffective. During the third experiment, the activating effects of a systemic treatment with testosterone were blocked by stereotaxic implants in the POM of the antiestrogen, tamoxifen, or the antiandrogen, flutamide. The effects of tamoxifen were more pronounced than those of flutamide. In addition, tamoxifen was active in all parts of the POM while a behavioral inhibition was observed only for flutamide implants which were located in the caudal part of the nucleus. Taken together, these results demonstrate that the sexually dimorphic POM is the area where the behaviorally active estrogenic metabolites of T have to be produced. The estradiol derived from T aromatization presumably acts within the POM to activate copulation as demonstrated by the effectiveness of DES implanted in this region. Androgens also have a direct action on sexual behavior as suggested by the partial inhibition observed in flutamide-treated birds. It is, however, suggested that androgens and estrogens do not act in the same brain area to activate behavior. [less ▲] Detailed reference viewed: 6 (1 ULg) Application au tilapia Oreochromis aureus d'une technique électronique d'identification individuellePoncin, Pascal ; Mélard, Charles ; Philippart, Jean-Claude ![]() in Cahiers d'Ethologie (1990), 10(3-4), 441-446 Detailed reference viewed: 31 (1 ULg) Role of the Conserved Amino Acids of the 'Sdn' Loop (Ser130, Asp131 and Asn132) in a Class a Beta-Lactamase Studied by Site-Directed Mutagenesis; Joris, Bernard ; et alin Biochemical Journal (1990), 271(2), 399-406 Ser130, Asp131 and Asn132 ('SDN') are highly conserved residues in class A beta-lactamases forming one wall of the active-site cavity. All three residues of the SDN loop in Streptomyces albus G beta ... [more ▼] Ser130, Asp131 and Asn132 ('SDN') are highly conserved residues in class A beta-lactamases forming one wall of the active-site cavity. All three residues of the SDN loop in Streptomyces albus G beta-lactamase were modified by site-directed mutagenesis. The mutant proteins were expressed in Streptomyces lividans, purified from culture supernatants and their kinetic parameters were determined for several substrates. Ser130 was substituted by Asn, Ala and Gly. The first modification yielded an almost totally inactive protein, whereas the smaller-side-chain mutants (A and G) retained some activity, but were less stable than the wild-type enzyme. Ser130 might thus be involved in maintaining the structure of the active-site cavity. Mutations of Asp131 into Glu and Gly proved to be highly detrimental to enzyme stability, reflecting significant structural perturbations. Mutation of Asn132 into Ala resulted in a dramatically decreased enzymic activity (more than 100-fold) especially toward cephalosporin substrates, kcat. being the most affected parameter, which would indicate a role of Asn132 in transition-state stabilization rather than in ground-state binding. Comparison of the N132A and the previously described N132S mutant enzymes underline the importance of an H-bond-forming residue at position 132 for the catalytic process. [less ▲] Detailed reference viewed: 5 (4 ULg) Heat transport in dielectric crystals at low temperature: A variational formulation based on extended irreversible thermodynamicsLebon, Georgy ; Dauby, Pierre ![]() in Physical Review (1990), 42 We propose a variational principle applicable to the heat-transport equations derived some years ago by Guyer and Krumhansl [Phys. Rev. 133, 1411 (1964); 148, 766 (1966); 148, 778 (1966)] to describe heat ... [more ▼] We propose a variational principle applicable to the heat-transport equations derived some years ago by Guyer and Krumhansl [Phys. Rev. 133, 1411 (1964); 148, 766 (1966); 148, 778 (1966)] to describe heat-wave propagation in dielectric crystals at low temperature. The variational principle appears as a generalization of Prigogine's minimum-entropy production criterion. The analysis is based on extended irreversible thermodynamics, which is used to derive the Guyer-Krumhansl equations from macroscopic arguments. [less ▲] Detailed reference viewed: 4 (3 ULg) Tropomyosin from the Striated Muscles of Carp (Cyprinus Carpio) and of Icefish (Channichthys Rhinoceratus)Feller, Georges ; ; Gerday, Charles ![]() in Archives Internationales de Physiologie et de Biochimie (1990), 98(5), 297-305 Tropomyosin of fast-twitch, slow-twitch and cardiac muscles of carp and icefish has been isolated by hydroxyapatite chromatography. The subunit distribution has been investigated by polyacrylamide gel ... [more ▼] Tropomyosin of fast-twitch, slow-twitch and cardiac muscles of carp and icefish has been isolated by hydroxyapatite chromatography. The subunit distribution has been investigated by polyacrylamide gel electrophoresis and by peptide mapping. The purified skeletal muscle tropomyosins all belong to the alpha family and differ from higher vertebrate tropomyosin by the lack of beta subunits. Specific alpha isotypes are however encountered in fast-twitch fibres (alpha w subunit) and slow-twitch or intermediate (pink) fibres (alpha and alpha w subunits). The amino acid compositions and the paracrystals formed by the carp alpha w alpha w and alpha alpha w tropomyosins do not differ markedly from that of rabbit alpha alpha chains. They differ however by their capability to inhibit the ATPase activity of rabbit skeletal muscle acto-HMM system. A beta-like subunit is found in carp cardiac tropomyosin, in the proportion of 25% of the native protein, but not in icefish heart. [less ▲] Detailed reference viewed: 10 (0 ULg) Formation of P Cygni line profiles in relativistically expanding atmospheresHutsemekers, Damien ; Surdej, Jean ![]() in Astrophysical Journal (1990), 361 The probabilistic approach of Surdej (1979) is followed to generalize the Sobolev (1958) formalism to the case of special relativity, in order to interpret accurately the P Cygni line profiles observed in ... [more ▼] The probabilistic approach of Surdej (1979) is followed to generalize the Sobolev (1958) formalism to the case of special relativity, in order to interpret accurately the P Cygni line profiles observed in the spectrum of broad absorption-line quasars and supernovae. The expressions of the source function and of the line profile are derived, and it is shown that the relativistic P Cygni line profiles are significantly different from those computed in the framework of the classical theory. Thus, for increasing values of the terminal wind velocity, the red emission wing becomes definitely narrower than the blue one, while the line center emission increases. This is no longer symmetrical in accordance with the relativistic expression of the Doppler effect. [less ▲] Detailed reference viewed: 15 (4 ULg) Les Cajuns de LouisianeSacré, Robert ![]() in Prologue (1990), (232), 43-45 Detailed reference viewed: 6 (0 ULg) La prévention des faillites au sein des Petites et Moyennes Entreprises : application de modèles statistiques simples au cas belgeVan Caillie, Didier ![]() in La Vie au Bureau (1990) Après avoir rappelé l'importance du phénomène de la faillite et la manière dont de nombreuses PME entrent insidieusement dans un processus de faillite et de défaillance, cet article présente quelques ... [more ▼] Après avoir rappelé l'importance du phénomène de la faillite et la manière dont de nombreuses PME entrent insidieusement dans un processus de faillite et de défaillance, cet article présente quelques modèles statistiques simples qui s'avèrent à la fois utiles et calculables dans le contexte belge du début des années '90. [less ▲] Detailed reference viewed: 95 (3 ULg) Variational Metric and Exponential Penalization; Tossings, Patricia ![]() in Journal of Optimization Theory & Applications (1990), 67(1), 185-192 Attouch and Wets have introduced recently a variational metric between closed proper convex functions. The aim of this note is to give an estimation of this metric in the case of the exponential penalties ... [more ▼] Attouch and Wets have introduced recently a variational metric between closed proper convex functions. The aim of this note is to give an estimation of this metric in the case of the exponential penalties. We can therefore recover some convergence results for the exponential penalty method. [less ▲] Detailed reference viewed: 12 (2 ULg) Engineering a Novel Beta-Lactamase by a Single Point Mutation; Joris, Bernard ; et alin Protein Engineering (1990), 4(1), 79-86 beta-Lactamases are widespread and efficient bacterial enzymes which play a major role in bacterial resistance to penicillins and cephalosporins. In order to elucidate the role of the residues lying in a ... [more ▼] beta-Lactamases are widespread and efficient bacterial enzymes which play a major role in bacterial resistance to penicillins and cephalosporins. In order to elucidate the role of the residues lying in a conserved loop of the enzymatic cavity of the active-site serine Streptomyces albus G beta-lactamase, modified proteins were produced by oligo-directed mutagenesis. Mutation of Asn116, which lies on one side of the active site cavity pointing to the substrate-binding site, into a serine residue resulted in spectacular modifications of the specificity profile of the enzyme. That replacement yielded an enzyme with a nearly unchanged activity towards good penicillin substrates. In sharp contrast its efficiency in hydrolysing cephalosporins was drastically reduced, the best substrates suffering the largest decrease in the second-order rate constant for serine acylation. In fact that single mutation generated a truly new enzyme behaving exclusively as a penicillinase, a situation which is never encountered to the same degree in any of the numerous naturally occurring variants of class A beta-lactamases. [less ▲] Detailed reference viewed: 6 (1 ULg) |
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