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See detailTreatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: results from a randomized phase II study and long-term follow-up of 71 patients.
Hellstrom-Lindberg, E.; Ahlgren, T.; Beguin, Yves ULg et al

in Blood (1998), 92(1), 68-75

Treatment with erythropoietin (epo) may improve the anemia of myelodysplastic syndromes (MDS) in approximately 20% of patients. Previous studies have suggested that treatment with the combination of ... [more ▼]

Treatment with erythropoietin (epo) may improve the anemia of myelodysplastic syndromes (MDS) in approximately 20% of patients. Previous studies have suggested that treatment with the combination of granulocyte colony-stimulating factor (G-CSF) and epo may increase this response rate. In the present phase II study, patients with MDS and anemia were randomized to treatment with G-CSF + epo according to one of two alternatives; arm A starting with G-CSF for 4 weeks followed by the combination for 12 weeks, and arm B starting with epo for 8 weeks followed by the combination for 10 weeks. Fifty evaluable patients (10 refractory anemia [RA], 13 refractory anemia with ring sideroblasts [RARS], and 27 refractory anemia with excess blasts [RAEB]) were included in the study, three were evaluable only for epo as monotherapy and 47 for the combined treatment. The overall response rate to G-CSF + epo was 38%, which is identical to that in our previous study. The response rates for patients with RA, RARS, and RAEB were 20%, 46%, and 37%, respectively. Response rates were identical in the two treatment groups indicating that an initial treatment with G-CSF was not neccessary for a response to the combination. Nine patients in arm B showed a response to the combined treatment, but only three of these responded to epo alone. This suggests a synergistic effect in vivo by G-CSF + epo. A long-term follow-up was made on 71 evaluable patients from both the present and the preceding Scandinavian study on G-CSF + epo. Median survival was 26 months, and the overall risk of leukemic transformation during a median follow-up of 43 months was 28%. Twenty patients entered long-term maintenance treatment and showed a median duration of response of 24 months.The international prognostic scoring system (IPSS) was effective to predict survival, leukemic transformation, and to a lesser extent, duration of response, but had no impact on primary response rates. [less ▲]

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See detailHigh temperature catalysts through sol-gel synthesis
Lecloux, A. J.; Pirard, Jean-Paul ULg

in Journal of Non-Crystalline Solids (1998), 225

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See detailGround-based infrared solar spectroscopic measurements of carbon monoxide during 1994 Measurement of Air Pollution From Space flights
Pougatchev, N. S.; Jones, N. B.; Connor, B. J. et al

in Journal Of Geophysical Research. Atmospheres (1998), 103(D15), 19317-19325

Results of the comparison of carbon monoxide ground-based infrared solar spectroscopic measurements with data obtained during 1994 Measurement of Air Pollution From Space (MAPS) flights are presented ... [more ▼]

Results of the comparison of carbon monoxide ground-based infrared solar spectroscopic measurements with data obtained during 1994 Measurement of Air Pollution From Space (MAPS) flights are presented. Spectroscopic measurements were performed correlatively with April and October MAPS flights by nine research groups from Belgium, Canada, Germany, Japan, New Zealand, Russia, and the United States. Characterization of the techniques and error analysis were performed. The role of the CO a priori profile used in the retrieval was estimated. In most cases an agreement between spectroscopic and MAPS data is within estimated MAPS accuracy of +/-10%. [less ▲]

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See detailEvidence For The Occurrence Of Endophytic Prokaryotic Contaminants In Micropropogated Plantlets Of Prunus Cerasus Cv. 'Montmorency'
Kamoun, R.; Lepoivre, Philippe ULg; Boxus, P.

in Plant Cell, Tissue & Organ Culture (1998), 52(1-2),

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See detailEffect of Ketoprofen on Paf-Induced Bovine Platelet Aggregation
Bastos da Silva, Miriam; Gustin, Pascal ULg; Herion, Francine ULg et al

in Veterinary Journal (1998), 155(2), 201-203

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See detailFree fatty acids regulate the uncoupling protein and alternative oxidase activities in plant mitochondria.
Sluse, Francis ULg; Almeida, A. M.; Jarmuszkiewicz, W. et al

in FEBS Letters (1998), 433

Two energy-dissipating systems, an alternative oxidase and an uncoupling protein, are known to exist in plant mitochondria. In tomato fruit mitochondria linoleic acid, a substrate for the uncoupling ... [more ▼]

Two energy-dissipating systems, an alternative oxidase and an uncoupling protein, are known to exist in plant mitochondria. In tomato fruit mitochondria linoleic acid, a substrate for the uncoupling protein, inhibited the alternative oxidase-sustained respiration and decreased the ADP/O ratio to the same value regardless of the level of alternative oxidase activity. Experiments with varying concentrations of linoleic acid have shown that inhibition of the alternative oxidase is more sensitive to the linoleic acid concentration than the uncoupling protein activation. It can be proposed that these dissipating systems work sequentially during the life of the plant cell, since a high level of free fatty acid-induced uncoupling protein activity excludes alternative oxidase activity. [less ▲]

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See detailTumeur de la granulosa chez la jument. Description d'un cas clinique et revue bibliographique.
De Behr, Vanessa; Saunders, Jimmy; Cassart, Dominique ULg et al

in Annales de Médecine Vétérinaire (1998), 142

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See detailHemodynamic effects of epinephrine associated to an epidural clonidine-bupivacaine mixture during combined lumbar epidural and general anesthesia.
Senard, Marc ULg; Ledoux, Didier ULg; Darmont, Pascaline ULg et al

in Acta Anaesthesiologica Belgica (1998), 49(3), 167-73

Clonidine or epinephrine are frequently combined to epidural local anesthetics to strengthen sensory block and prolong analgesia. Both drugs impair the hemodynamic profile of central neural blockade but ... [more ▼]

Clonidine or epinephrine are frequently combined to epidural local anesthetics to strengthen sensory block and prolong analgesia. Both drugs impair the hemodynamic profile of central neural blockade but the effects of their combination on arterial pressure and heart rate are not known and were examined in this double-blind prospective randomised study. Forty four patients scheduled for lumbar disc surgery were allocated to two groups. Epidural anesthesia was obtained by administration of 150 micrograms clonidine in 15 ml bupivacaine 0.25% solution without (group C) or with (group C + E) 37.5 micrograms epinephrine. Systolic, mean, diastolic arterial pressure and heart rate were measured throughout the study. Combined epidural and general anesthesia induced a significant decrease in arterial pressure and heart rate in both groups. SAP and MAP decreased significantly less in the patients receiving epinephrine. Low dose epidural epinephrine decreases arterial pressure instability during combined epidural and general anesthesia. [less ▲]

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See detailSystème rénine-angiotensine II-aldostérone: quoi de neuf en 1998?
Krzesinski, Jean-Marie ULg

in Médisphère (1998), 91(12-13),

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See detailAltered apoptotic profiles in irradiated patients with increased toxicity
Ozsahin, Mahmut; Miralbell, Raymond; Emery, Gillian et al

in International Journal of Radiation, Oncology, Biology, Physics (1998), 42(Supplément), 135

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See detailThe in vitro and in vivo production of a 31.5-kD keratinolytic subtilase from Microsporum canis and the clinical status in naturally infected cats.
Mignon, Bernard ULg; Nikkels, Arjen ULg; Pierard, Gérald ULg et al

in Dermatology : International Journal for Clinical & Investigative Dermatology (1998), 196(4), 438-441

BACKGROUND: Microsporum-canis-infected cats, especially the asymptomatic infected ones, are mainly responsible for the zoonotic disease. The important variability of the clinical signs in cats is poorly ... [more ▼]

BACKGROUND: Microsporum-canis-infected cats, especially the asymptomatic infected ones, are mainly responsible for the zoonotic disease. The important variability of the clinical signs in cats is poorly understood. Recently, a 31.5-kD keratinolytic subtilase was found to be a putative virulence factor. OBJECTIVE: To investigate the possible relationship between the clinical status of dermatophytic cats and the production of the keratinase. METHODS: Seven M. canis strains isolated either from clinically affected, asymptomatic infected or mechanical carrier cats were tested for the in vitro production of the enzyme. The immunohistochemical detection of the enzyme was also assessed in skin biopsies of 4 symptomatic and 7 asymptomatic naturally infected cats. RESULTS: All the strains produced in vitro a 31.5-kD keratinolytic subtilase. The enzyme was present in all but 1 of the infected cats. CONCLUSION: The production of the keratinase is not a factor directly responsible for the clinical picture seen in M.-canis-infected cats. [less ▲]

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See detailScintimammography with technetium-99m methoxyisobutylisonitrile: results of a prospective European multicentre trial.
Palmedo, H.; Biersack, H. J.; Lastoria, S. et al

in European Journal of Nuclear Medicine (1998), 25(4), 375-85

The aim of the trial was to determine the diagnostic accuracy of scintimmammography with technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) in the detection of primary breast cancer and to verify its ... [more ▼]

The aim of the trial was to determine the diagnostic accuracy of scintimmammography with technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) in the detection of primary breast cancer and to verify its clinical usefulness. A total of 246 patients with a suspicious breast mass or positive mammogram were included in this prospective European multicentre trial. At 5 min and 60 min (optional) p.i. two lateral prone images were acquired for 10 min each; 30 min p.i. one anterior image was acquired for 10 min. There were 253 lesions (195 palpable and 58 non-palpable), in respect of which histology revealed 165 cancers and 88 benign lesions. Institutional and blinded read results were correlated to core laboratory histopathology results obtained during excisional biopsy. Diagnostic accuracy for the detection of breast cancer was calculated per lesion. The overall sensitivity and specificity of blinded read scintimammography were 71% and 69%, respectively. For palpable lesions, the sensitivity of blinded read and institutional read scintimammography was 83% and 91%, respectively. Sensitivity was not dependent on the density of the breast tissue. Invasive ductal and invasive lobular cancers showed similar sensitivity. The sensitivity and specificity of mammography were 91% and 42%, respectively, and did not depend on the tumour size. In 60% of false-negative mammograms, 99mTc-MIBI was able to diagnose malignancy (true-positive). High-quality imaging with 99mTc-MIBI has a high diagnostic accuracy for the detection of primary breast cancer. Used as a complementary method, scintimammography with 99mTc-MIBI can help to diagnose breast cancer at an earlier stage in patients with dense breasts. [less ▲]

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See detailPharma-clinics. Le medicament du mois. Le formoterol (Oxis Turbohaler).
Scheen, André ULg

in Revue Médicale de Liège (1998), 53(11), 715-8

Formoterol, commercialized by Astra under the trade name Oxis, is a new potent and selective agonist of beta-2 adrenergic receptors, which is used with a specific device (Turbohaler) allowing effective ... [more ▼]

Formoterol, commercialized by Astra under the trade name Oxis, is a new potent and selective agonist of beta-2 adrenergic receptors, which is used with a specific device (Turbohaler) allowing effective inhalation. Bronchodilatation occurs rapidly, within 1-3 minutes after inhalation, and lasts about 12 hours after the administration of a unique dose. Oxis Turbohaler is indicated to reduce symptoms associated with bronchial obstruction in asthmatic patients when the control of asthma is not achieved with inhaled corticoid therapy. It is not indicated for the treatment of acute crisis. It is presented as powder vials for inhalation (4.5 or 9 micrograms per dose). The usual dose in adults is 1-2 inhalations 1-2 times per day, in the morning and/or in the evening (bedtime administration should be recommended in case of nocturnal asthma). There is not enough data for treating children. The lowest dose allowing adequate control of asthma should be selected for chronic treatment. [less ▲]

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See detailModelling Hydrodynamically Dominated Marine Ecosystems
Delhez, Eric ULg

in Journal of Marine Systems (1998), 1-2

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See detailPersonnalité et contenus implicites
Garcet, Serge ULg

in Revue des Psychologues et Psychiatres de l'AIGS (1998), 1

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See detailEvaluation de l'impact du cours d'éducation par la technologie
Hubert, Sylviane; Denis, Brigitte ULg

in Informations pédagogiques (1998), 40

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See detailHistoire de fermiers ou de clochers ? Les boerenmarkten: émergence des marchés fermiers en Flandre
Stassart, Pierre M ULg

in Environnement et Société (1998), (21), 99-116

Introduction de l'article : Comme de nombreuses histoires, celle des boerenmarkten (marchés fermiers en Flandre) débute sur fond de revendications. La fusion des communes, imposée par l'Etat central, n ... [more ▼]

Introduction de l'article : Comme de nombreuses histoires, celle des boerenmarkten (marchés fermiers en Flandre) débute sur fond de revendications. La fusion des communes, imposée par l'Etat central, n'est pas sans entraîner quelques réactions de protestation. En Flandre, le petit village de Baaigem, non loin de Gand, fait de la résistance : un gros rocher est symboliquement planté à l'entrée du village en signe de protestation contre l'intégration contrainte dans une entité plus vaste, celle de la commune de Gavere. Mais cette poussée revendicatrice va entraîner Baaigem de l'opposition à la fusion jusqu'à la reconstruction de son identité villageoise. En 1978, Baaigem se saisit du programme de "l'année du village" en Flandre pour redécouvrir son patrimoine architectural et rural. Cette quête d'harmonie entre le passé et le présent, l'homme et la nature, le village et ses paysages attire de nombreux artistes qui trouveront dans ce cadre champêtre leur source d'inspiration. La convivialité vécue lors de l'organisation des manifestations fait rêver au paradis perdu de la démocratie participative que l'Etat central a confisqué avec l'opération de fusion. Le village de Baaigem se construit ainsi en opposition au monde de la ville, de l'éphémère et de l'impersonnel, de la bureaucratie. Mais la force du petit village réside encore davantage dans la médiatisation, dans l'image de Baaigem que le programme "l'année du village" a fait circuler en Flandre à travers journaux, radios et TV : Baaigem est devenu un paysage champêtre où pointe le clocher de l'église, une rue, une place, un café qui piègent la sympathie des visiteurs, lecteurs ou téléspectateurs... Cette sympathie est d'autant plus spontanée que Baaigem incarne la résistance du petit face au grand, de la tradition face à l'urbanisation et la modernisation. Ainsi, un peu malgré eux les "villageois" deviennent fiers de leur village et de leur mode de vie campagnard. Ils se laissent redéfinir à travers un double espace : l'espace local, celui de l'animation de "l'année du village", et l'espace virtuel des médias dont les retombées locales définissent aussi les habitants de Baaigem. [less ▲]

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See detailComparaison empirique de méthodes de prédiction en régression linéaire multiple
Fonton, N. H.; Palm, Rodolphe ULg

in Revue de Statistique Appliquée (1998), XLVI(3), 53-64

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See detailTesting the tectonic significance of some parameters of longitudinal river profiles: the case of the Ardenne (Belgium, NW Europe)
Demoulin, Alain ULg

in Geomorphology (1998), 24

The longitudinal profiles of 24 rivers of 3rd to 5th order have been analyzed in order to recognize the regional tectonic differentiation pattern of the Ardenne, a Paleozoic massif of NW Europe. Data ... [more ▼]

The longitudinal profiles of 24 rivers of 3rd to 5th order have been analyzed in order to recognize the regional tectonic differentiation pattern of the Ardenne, a Paleozoic massif of NW Europe. Data collected exclusively from 1/25,000 topographic maps were used to define a set of parameters related to the geometry of the profile and proxies for river bedload and drainage area. Validation of the proxy defined for the bedloadrdischarge ratio demonstrates its potential use for inter-river comparison based on its value at the river mouth; it is however inadequate to estimate the ratio changes along a given stream course. This proxy has been computed to estimate the portion accounted for by hydrodynamic factors in the river bed profiling. Thus, outliers to the correlation function linking it to the river bed gradient have been considered as undergoing other influences, principally of lithologic or tectonic origin. Most indicative of the computed profile parameters are those related to the concavity of the profile. Four more or less regional longitudinal profile types are recognized which are partly determined by differential tectonic movement. The combined analysis of all the parameters confirms the current uplift of the NE Ardenne and points to a subsidence of the Namur area with respect to its SW and SE surroundings. Whether periglacial or tectonic in origin, the Upper Pleistocene lowering of a local base-level has also been identified in the Famenne. Another conclusion of this study is that in order to evidence tectonic influences and to avoid any misinterpretation in a region of complex geologic and geomorphic history and moderate tectonic activity, it is essential to consider a number of parameters and to consider their significance within the framework of detailed geologic setting and morphogenetic history. [less ▲]

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See detailBiorthogonal wavelets in H-m(R)
Bastin, Françoise ULg; Boigelot, Christine

in Journal Of Fourier Analysis And Applications (1998), 4(6), 749-768

This article is concerned with constructions of biorthogonal basis of compactly supported wavelets in Sobolev spaces of integer order. Using techniques of [1] and [2], the results presented here ... [more ▼]

This article is concerned with constructions of biorthogonal basis of compactly supported wavelets in Sobolev spaces of integer order. Using techniques of [1] and [2], the results presented here generalize to Sobolev spaces some constructions of Cohen et al. [7] and Chui and Wang [5] established in L-2(R). [less ▲]

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See detailDetermination of the total glucosinolate content in rapeseed seeds by liquid chromatography: comparative study between the rapid isocratic and the reference gradient methods by a ring test
Quinsac, A.; Krouti, M.; Ribaillier, D. et al

in Ocl-Oleagineux Corps Gras Lipides (1998), 5(5), 398-406

Isocratic liquid chromatography (LC) on cyanopropyl bonded silica column is an alternative method to gradient IC on octadecyl bonded silica column involved in the standardized method for total ... [more ▼]

Isocratic liquid chromatography (LC) on cyanopropyl bonded silica column is an alternative method to gradient IC on octadecyl bonded silica column involved in the standardized method for total glucosinolotes (GSL) analysis in rapeseed seeds. Its advantages consist in more simple apparatus and eluent, and a shorter analysis duration. In the aim of a next standardization of isocratic LC, the performances of both methods ore compared on three rapeseed samples during a ring-test including six laboratories. Statistical treatment or the results according to ISO 5725 shows, with a risk level of 5%, the equivalency of both methods to determine total GSL content in rapeseed seeds. The elution mode appears to have no significant effect on results in opposite to the internal standard when its purity is not well-known. [less ▲]

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See detailSelf-consistent approximations in relativistic plasmas: Quasiparticle analysis of the thermodynamic properties
Vanderheyden, Benoît ULg; Baym, G.

in Journal of Statistical Physics (1998), 93(3-4), 843-861

We generalize the concept of conserving, Phi-derivable, approximations to relativistic field theories. Treating the interaction field as a dynamical degree of freedom, we derive the thermodynamic ... [more ▼]

We generalize the concept of conserving, Phi-derivable, approximations to relativistic field theories. Treating the interaction field as a dynamical degree of freedom, we derive the thermodynamic potential in terms of fully dressed propagators, an approach which allows us to resolve the entropy of a relativistic plasma into contributions from its interacting elementary excitations. We illustrate the derivation for a hot relativistic system governed by electromagnetic interactions. [less ▲]

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See detailFacial reactions to emotional facial expressions: affect or cognition?
Hess, U; Philippot, P; Blairy, Sylvie ULg

in Cognition & Emotion (1998), 12(4), 509-531

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See detailAspects de la gestion de clubs de football belges francophones. Comparaison en fonction du niveau de jeu
Cloes, Marc ULg; Chapelle, Jean-yves; Ledent, Maryse et al

in AES Magazine (1998), 52

Dans la société occidentale actuelle, les loisirs occupent une part extrêmement importante dans le style de vie de la majorité des individus. Bien que les loisirs soient caractérisés par une très grande ... [more ▼]

Dans la société occidentale actuelle, les loisirs occupent une part extrêmement importante dans le style de vie de la majorité des individus. Bien que les loisirs soient caractérisés par une très grande diversité, le sport figure parmi les activités qui y sont le plus fréquemment associés. Au fil des ans, le sport a pris de plus en plus d'importance, non seulement au point de vue de nombre de personnes concernées mais également au point de vue de l'implication financière qui résulte de sa pratique. ... [less ▲]

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See detailThe Perturbed Generalized Proximal Point Algorithm
Alexandre, Patrick; Nguyen, Van Hien; Tossings, Patricia ULg

in RAIRO : Modélisation Mathématique et Analyse Numérique (Mathematical Modelling and Numerical Analysis) (1998), 32(2), 223-253

During the last years, different modifications were introduced in the proximal point algorithm devloped by R.T. Rockafellar for searching a zero of a maximal monotone operator on a real Hilbert space. We ... [more ▼]

During the last years, different modifications were introduced in the proximal point algorithm devloped by R.T. Rockafellar for searching a zero of a maximal monotone operator on a real Hilbert space. We combine these modifications to get a new version of this algorithm. We take simultaneously into account a variable metric, a perturbation and a kind of relaxation. Our work takes place in the context of the variational convergence theory. [less ▲]

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See detailRadiative transition probabilities for forbidden lines in singly ionized cobalt (Co II)
Quinet, Pascal ULg

in Astronomy and Astrophysics. Supplement Series (1998), 129

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See detailLes thérapeutiques à visée spécifiquement osseuse dans le traitement de l'ostéoporose postménopausique. Aspects pharmaco-économiques
Reginster, Jean-Yves ULg; Ben Sedrine, Wafa ULg; Gosset, Christiane ULg

in Revue Médicale de Liège (1998), 53(5), 290-293

Fairly new economic evaluations were, so far, properly conducted in the field of prevention and treatment of osteoporosis. This lack of studies is likely to be related to the pathophysiology and the ... [more ▼]

Fairly new economic evaluations were, so far, properly conducted in the field of prevention and treatment of osteoporosis. This lack of studies is likely to be related to the pathophysiology and the natural course of the disease, the small number of disease-specific instruments allowing the evaluation of quality of life changes following fractures and the frequent interaction of osteoporotic treatments with other body systems. Notwithstanding a lot of efforts have to be brought before economic evaluations in osteoporosis become a key determinant of Public Health strategies, it remains of prime interest to promote this type of research taking into account the importance of the social, human and economic burden of this disease. [less ▲]

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See detailMicrobiological control of apple postharvest diseases: a case of study
Jijakli, Haissam ULg; Lepoivre, Philippe ULg; Grevesse, C.

in revista corpoica (1998), 2

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See detailA new time domain to estimate windkessel parameters of pulmonary circulation
LAMBERMONT, Bernard ULg; GERARDP; POTTY, P et al

in American Journal of Respiratory & Critical Care Medicine (1998), 157

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See detailLa notion de 'mêmes parties', condition de la litispendance communautaire
Boularbah, Hakim ULg

in Journal des Tribunaux (1998)

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See detailLe cartilage articulaire peut-il se régénérer ? (1ère partie)
Henrotin, Yves ULg; Reginster, Jean-Yves ULg

in Le Généraliste (1998), 414

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See detailRed blood cell precursor mass as an independent determinant of serum erythropoietin level.
Cazzola, M.; Guarnone, R.; Cerani, P. et al

in Blood (1998), 91(6), 2139-45

Serum erythropoietin (sEpo) concentration is primarily related to the rate of renal production and, under the stimulus of hypoxia, increases exponentially as hemoglobin (Hb) decreases. Additional factors ... [more ▼]

Serum erythropoietin (sEpo) concentration is primarily related to the rate of renal production and, under the stimulus of hypoxia, increases exponentially as hemoglobin (Hb) decreases. Additional factors, however, appear to influence sEpo, and in this work, we performed studies to evaluate the role of the red blood cell precursor mass. We first compared the relationship of sEpo with Hb in patients with low versus high erythroid activity. The first group included 27 patients with erythroid aplasia or hypoplasia having serum transferrin receptor (sTfR) levels < 3 mg/L (erythroid activity < 0.6 times normal), while the second one included 28 patients with beta-thalassemia intermedia having sTfR levels > 10 mg/L (erythroid activity > 2 times normal). There was no difference between the two groups with respect to Hb (8.3 +/- 1.6 v 8.0 +/- 1.3 g/dL, P > .05), but sEpo levels were notably higher in patients with low erythroid activity (1,601 +/- 1,542 v 235 +/- 143 mU/mL, P < . 001). In fact, multivariate analysis of variance (ANOVA) showed that, at any given Hb level, sEpo was higher in patients with low erythroid activity (P < .0001). Twenty patients undergoing allogeneic or autologous bone marrow transplantation (BMT) were then investigated. A marked increase in sEpo was seen in all cases at the time of marrow aplasia, disproportionately high when compared with the small decrease in Hb level. Sequential studies were also performed in five patients with iron deficiency anemia undergoing intravenous (IV) iron therapy. Within 24 to 72 hours after starting iron treatment, marked decreases in sEpo (up to one log magnitude) were found before any change in Hb level. Similar observations were made in patients with megaloblastic anemia and in a case of pure red blood cell aplasia. These findings point to an inverse relationship between red blood cell precursor mass and sEpo: at any given Hb level, the higher the number of red blood cell precursors, the lower the sEpo concentration. The most likely explanation for this is that sEpo levels are regulated not only by the rate of renal production, but also by the rate of utilization by erythroid cells. [less ▲]

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See detailThe american-european consensus conference on ARDS, Part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling
Artigas, A.; Bernard, G. R.; Carlet, J. et al

in Intensive Care Medicine (1998), 24

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See detailResultaten van het gebruikssporenonderzoek op silexmateriaal van het Goudenleeuwplein in Gent
Caspar, Jean-Paul; Rots, Veerle ULg

in Stadsarcheologie (1998), 22(1), 8

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See detailLes karsts siliceux d'Afrique
Vicat, Jean-Paul; Willems, Luc ULg

in Géosciences au Cameroun @ collection Géocam (1998), 1

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See detailConservative Mutations In The Immunosuppressive Region Of The Bovine Leukemia Virus Transmembrane Protein Affect Fusion But Not Infectivity In Vivo
GATOT, Jean-Stéphane ULg; Callebaut, I.; Mornon, Jp. et al

in Journal of Biological Chemistry (1998), 273(21),

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See detailLe nouveau Trésor de la Cathédrale de Liège
George, Philippe ULg; Pirenne, Françoise

in Feuillets de la Cathédrale de Liège (1998)

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See detailL'erytheme necrolytique migrateur.
Dandrifosse, J. F.; Dandrifosse, A. C.; Pierard, Gérald ULg et al

in Revue Médicale de Liège (1998), 53(12), 778-83

Necrolytic migratory erythema (NME) is generally associated with glucagonoma. It waxes and wanes by successive relapses and remissions. The clinical and microscopical diagnosis is complex. In addition to ... [more ▼]

Necrolytic migratory erythema (NME) is generally associated with glucagonoma. It waxes and wanes by successive relapses and remissions. The clinical and microscopical diagnosis is complex. In addition to glucagonoma treatments, the administration of corticoids, aminoacids, zinc or essential fatty acids can be helpful. There exist several etiological hypotheses for NME. These are based on modifications of pancreatic enzyme activities and on variations of aminoacids, fatty acids, zinc or glucagon concentrations. [less ▲]

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See detailLes pucerons sont-ils résistants aux insecticides en Belgique ?
Francis, Frédéric ULg; Haubruge, Eric ULg; Gaspar, C.

in Parasitica (1998), 54(4), 151-161

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See detailAn Efficient Sampling Technique Used to Detect Four Foodborne Pathogens on Pork and Beef Carcasses in Nine Belgian Abattoirs
Korsak Koulagenko, Nicolas ULg; Daube, Georges ULg; Ghafir, Yasmine et al

in Journal of Food Protection (1998), 61(5), 535-541

The method presented in this paper should prove useful in assessing the effectiveness of HACCP plans developed in slaughterhouses. Samples were collected by swabbing well-defined areas of pork and beef ... [more ▼]

The method presented in this paper should prove useful in assessing the effectiveness of HACCP plans developed in slaughterhouses. Samples were collected by swabbing well-defined areas of pork and beef carcasses with sterile gauze. Between 160 and 420 half-carcasses were swabbed in each of nine pork or beef slaughterhouses. Swabs from five carcasses were placed in the same sterile Stomacher bag, constituting a single composite sample. Standard or validated analytical methods were used to isolate and characterize four foodborne pathogens. Salmonella spp., Listeria monocytogenes, Campylobacter spp., and verocytotoxin-producing E. coli were detected, respectively, in 27, 2, 2, and 14% of the pork samples and 0, 22, 10, and 5% of the beef samples. Of the 10 samples positive for E. coli O157, only one yielded an isolate confirmed to be enterohemorrhagic. Since Salmonella spp. appear as the main contaminant port (27%) and L. monocytogenes as the main containment of beef (22%), any slaughterhouse sampling plan should include testing for the former in the case of pork carcasses and for the latter in the case of beef carcasses. One should also test regularly for the presence of E. coli O157 and Campylobacter spp. in pork and beef abattoirs. The method presented here is an easy way to assess the contamination rate of carcasses at the end of the slaughtering process. [less ▲]

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See detailCompensatory growth in Belgian Blue bulls previously maintained at two growing rates on pasture: animal performance and meat characteristics
Hornick, Jean-Luc ULg; Raskin, Pascale; Clinquart, Antoine ULg et al

in Animal Science (1998), 67(3), 427-434

A comparison was made between finishing systems with Belgian Blue bulls of the double-muscle type, in order to assess the response in terms of compensatory growth when bulls were grazed at a high stocking ... [more ▼]

A comparison was made between finishing systems with Belgian Blue bulls of the double-muscle type, in order to assess the response in terms of compensatory growth when bulls were grazed at a high stocking rate. Two groups of 8 bulls (256.5 kg liveweight) were grazed on Lolium perenne and Trifolium repens pasture during an initial period of 135 days (period I). One group grazed at a stocking rate of 6/ha allowing for normal growth at pasture (NGP); the other group grazed at a stocking rate of 10/ha (low growth at pasture, LGP). Both groups were then finished indoors (period II) with a concentrate based on dried sugarbeet pulp. Eight control bulls were also finished indoors on the concentrate diet during periods I and II (CG). Bulls were slaughtered according to a similar finishing state. Liveweight gains were 1.47, 1.10 and 0.52 kg daily (P<0.001) during period I in CG, NGP and LGP groups respectively. Corresponding liveweight gains during period II were 1.22, 1.37 and 1.50 kg daily. The LGP group had lower feed conversion ratios, slaughter weights (P<0.05) and dressing proportions (P<0.01). The meat from the grazed bulls had lower cooking losses (P<0.05) and tended to have lower drip losses and higher tenderness. It also had a higher cholesterol (P<0.05) content. Large differences were observed in the fatty acid composition according to fat location (subcutaneous, intermuscular or intramuscular). The proportions of mono and polyunsaturated acids increased in the adipose tissue of those previously grazed. [less ▲]

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See detailAlcoholic liver disease: how to detect alcoholism?
Delwaide, Jean ULg

in Problem solving in hepatobiliary diseases (1998)

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See detailObesity and nutrition in children. The Belgian Luxembourg Child Study IV.
Guillaume, Michèle ULg; Lapidus, L.; Lambert, A.

in European Journal of Clinical Nutrition (1998), 52(5), 323-8

OBJECTIVE: To analyse the association between nutritional and familial factors and obesity in boys and girls. DESIGN: Randomized, cross-sectional population study. SETTING: Province de Luxembourg, Belgium ... [more ▼]

OBJECTIVE: To analyse the association between nutritional and familial factors and obesity in boys and girls. DESIGN: Randomized, cross-sectional population study. SETTING: Province de Luxembourg, Belgium. Subjects: One thousand and twenty-eight boys and girls in age strata 6-8, 8-10 and 10-12 y, comprising 70.3% of primary cohort. METHODS: Examinations included anthropometric measurements and questionnaires covering familial, socioeconomic and psychosocial factors. A three day dietary record was obtained in 955 children. This was analysed in relation to the anthropometric data. RESULTS: In comparison with similar studies from other regions and recommended allowances, the intakes of total energy, fat, particularly saturated fat and cholesterol, were high, while consumption of carbohydrate and fiber was low, as well as the polyunsaturated/saturated ratio of fat. Total energy intake showed no or weakly significant correlations with anthropometric factors. However, total fat (P=0.045) and saturated fat (P=0.0005) intake showed consistent positive correlations with body mass index (BMI, kg/m2) and skinfold thickness, with corresponding negative relationships to carbohydrate intake (P=0.034) in boys. Such relationships were also found when calculated as energy density. These associations were not statistically significant in girls. The high fat, low carbohydrate pattern of the nutritional status seemed to be more pronounced in families where the father had a low level of education (lipids, boys, P=0.0007), and where both parents were obese (saturated fat, boys, P=0.023), suggesting involvement of socioeconomic and familial factors. CONCLUSION: The lack of correlation between factors indicating obesity and total energy intake suggests that the positive energy balance causing obesity is due mainly to a low energy output. However, since energy intake measurements are imprecise, overeating can not be excluded, particularly since elevated consumption of food with high contents of fat, found in these children seems to be poorly regulated. [less ▲]

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See detailDetection of the lensing galaxy for the double QSO HE 1104-1805
Remy, M.; Claeskens, Jean-François ULg; Surdej, Jean ULg et al

in New Astronomy (1998), 3

High angular resolution ground-based direct imaging (V, R, I_c) of the double QSO HE 1104-1805 has been obtained with the NOT and NTT telescopes. Analysis of these data led to the first detection of the ... [more ▼]

High angular resolution ground-based direct imaging (V, R, I_c) of the double QSO HE 1104-1805 has been obtained with the NOT and NTT telescopes. Analysis of these data led to the first detection of the lensing galaxy. Direct imaging of HE 1104-1805 has subsequently been carried out with the Planetary Camera (WFPC2) through the F555W (nearly Johnson V) and F814W (nearly Kron-Cousins I_c) filters onboard HST. These images confirm the presence of the deflector between the two lensed quasar components (A & B). Direct imaging of this system in the near infrared (IR) at 2.2 mu-m (K'), with IRAC-2b at the Cassegrain focus of the ESO/MPI 2.2 m telescope, indicates that the additional component is indeed a very red extended object with magnitude K ~= 16.5. We present deconvolutions of the HST and IR images using the 2-channel PLUCY method. From the HST observations, we also report very accurate relative positions and brightnesses of the QSO components. By comparison between the ground-based and the HST observations, from February-March 1994 to November 1995, we possibly detect the fading of component A by ~ 0.3 magnitudes in the optical and a corresponding fading of B by about half this value. The observed monotonic decrease of the magnitude difference between B and A as a function of wavelength is consistent with a partial amplification of the A component by microlensing. Evolutionary models for galaxies show that, in order to produce the observed colour indices V - I_c > 2 and 4 < I_c - K < 4.5, the galaxy is likely to be of elliptical type with a redshift 0.95 < z < 1.4. This range is consistent with the redshift z=1.32 measured from the absorption lines of metallic species in the spectra of the quasar components. However, other values for the redshift of the lens inside this range cannot be excluded. This galaxy would presently be among the most distant known gravitational lenses. Several theoretical models are found to fit the observations. The simplest one is a singular isothermal sphere (SIS) lens immersed in an external shear with gamma=0.123. The derived mass-to-light ratio (11 h_50 M_Sun/L_Sun) for the galaxy is large but does not imply an excess of dark matter with respect to other well known lensing galaxies. [less ▲]

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See detailA formal definition of time in LOTOS (Full version)
Léonard, Luc; Leduc, Guy ULg

in Formal Aspects of Computing (1998), 10E

Enhanced Timed-LOTOS, denoted ET-LOTOS, is an extension of LOTOS that allows the modelling of real-time behaviours. It covers all the aspects of full LOTOS, including data types, it supports both a dense ... [more ▼]

Enhanced Timed-LOTOS, denoted ET-LOTOS, is an extension of LOTOS that allows the modelling of real-time behaviours. It covers all the aspects of full LOTOS, including data types, it supports both a dense and a discrete time domain and can manipulate time values as any other data values. A tutorial on ET-LOTOS, showing many application examples, has already been published elsewhere. The present paper adds to it by providing an in-depth presentation of its theoretical aspects. The complete semantics is given and explained, and its properties are studied. In particular, we prove that the semantics is consistent and that strong bisimulation is a congruence. This requires to deal carefully with the presence of negative premises in the operational semantics, which are necessary to express urgency. ET-LOTOS is also shown to be a conservative extension of LOTOS for guarded processes, and is the basis of the timed extension of LOTOS currently developed by ISO. To our knowledge, this is the first in-depth study of a language that combines data types and real-time behaviours. [less ▲]

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See detailGrandir en l'an 2000 : les parents et l'école maternelle
Crahay, Marcel ULg; Hindryckx, Geneviève ULg; Lafontaine, Annette ULg et al

in Point sur la Recherche en Education (Le) (1998), 6

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See detailLe projet CATSIUS CLAY
Charlier, Robert ULg; Collin, Frédéric ULg

in Bulletin du Groupement Belge de Mécanique des Roches (1998), 7

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See detailAnalyse de l'enseignement des activités physiques et sportives dans la perspective d'un traitement différencié des élèves de l'enseignement primaire
Piéron, Maurice ULg; Ledent, Maryse; Delfosse, Catherine et al

in Revue de l'Education Physique (1998), 38(1), 11-24

Afin de recueillir une image valide tu traitement différencié des élèves dans des leçons d'éducation physique, il est primordial de proposer une approche multidimensionnelle, prenant comme cible les ... [more ▼]

Afin de recueillir une image valide tu traitement différencié des élèves dans des leçons d'éducation physique, il est primordial de proposer une approche multidimensionnelle, prenant comme cible les différents acteurs du processus édagogique, à la fois les enseignants et les élèves. Par ailleurs, deux types d'informations devraient être récoltés afin de rendre compte de la réalité de la relation pédagogique: celles qui concernent les comportements et actions concrètes et celles relevant des valeurs, attitudes, perceptions et mécanismes de prise de décision. Les premières reposent sur l'observation alors que les secondes exigent l'interrogation des sujets. [less ▲]

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See detailLe Robinier faux acacia.
Jourez, Benoît ULg

in Courrier du Bois (1998), 38(120), 13-20

Le Robinier est une essence méconnue en Belgique dont l’emploi se limite bien souvent à la fixation des talus ou à l’ornementation des parcs et avenues. Cette espèce présente, cependant, de multiples ... [more ▼]

Le Robinier est une essence méconnue en Belgique dont l’emploi se limite bien souvent à la fixation des talus ou à l’ornementation des parcs et avenues. Cette espèce présente, cependant, de multiples caractéristiques susceptibles de rencontrer un grand intérêt auprès des sylviculteurs et des utilisateurs de bois. [less ▲]

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See detailTout ce qui brille et qui fait mal n'est pas migraine
DELVAUX, Valérie ULg; Schoenen, Jean ULg

in Ahead in Neurology (1998), 2

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See detailApplication of recombinant sucrose synthase large scale synthesis of ADP-glucose
Zervosen, Astrid ULg; Romer, Ulrike; Elling, Lothar

in Journal of Molecular Catalysis B : Enzymatic (1998), 5(1-4), 25-28

Abstract The synthesis of ADP-glucose with recombinant sucrose synthase from potato was combined with the synthesis of ADP from AMP and ATP catalysed by myokinase from rabbit muscle. By using the ... [more ▼]

Abstract The synthesis of ADP-glucose with recombinant sucrose synthase from potato was combined with the synthesis of ADP from AMP and ATP catalysed by myokinase from rabbit muscle. By using the repetitive-batch-technique we were able to reach enzyme productivities (mg ADP-glucose/U enzyme) of 28 mg/U sucrose synthase and 140 mg/U myokinase yielding 2.8 g ADP-glucose (55% yield). After product isolation, 2.2 g ADP-glucose was obtained corresponding to 44% overall yield. [less ▲]

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See detailIron metabolism and erythropoiesis after surgery.
van Iperen, C. E.; Kraaijenhagen, Rob J.; Biesma, D. H. et al

in British Journal of Surgery (1998), 85(1), 41-5

BACKGROUND: This was a prospective study comparing the effect of major and minor surgery on haematological variables concerning erythropoiesis, iron metabolism and acute-phase response proteins. METHODS ... [more ▼]

BACKGROUND: This was a prospective study comparing the effect of major and minor surgery on haematological variables concerning erythropoiesis, iron metabolism and acute-phase response proteins. METHODS: Thirty-one otherwise healthy patients, 15 having major orthopaedic surgery and 16 undergoing minor surgery, were studied. Blood samples were taken before surgery and 1, 4, 10 and 28 days after operation. RESULTS: Haemoglobin concentration was decreased for up to 4 weeks after surgery. Serum erythropoietin concentration and reticulocyte count were raised after major surgery only. Serum iron concentration dropped the day after major (to 23 per cent of its preoperative level) and minor (to 46 per cent of its preoperative level) surgery and remained lower for up to 28 days after major surgery. Serum transferrin concentration and transferrin saturation decreased after both types of surgery while ferritin concentration increased. Serum transferrin receptor concentration increased only 4 weeks after major surgery (P < 0.01). The interleukin 6 peak (day 1) was greater after major than minor surgery, as was the C-reactive protein peak (day 4). CONCLUSION: Both major and minor surgery induce a state of hypoferraemia in the presence of adequate iron stores. The degree of this transient form of 'anaemia of chronic disease' is related to the extent of surgery. Iron supplementation in the first weeks after surgery (if iron stores were normal before operation) is ineffective. [less ▲]

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See detailAnalytical solution of a simple artificial lighting scheme to test any lighting software
Embrechts, Jean-Jacques ULg

in Light and Engineering (1998), 6(4)

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See detailEvaluation of surgery procedures for tagging eel Anguilla anguilla (L.) with biotelemetry transmitters
Baras, Etienne; Jeandrain, Denys ULg

in Hydrobiologia (1998), 371/372

Externally attached telemetry transmitters are unsuitable to tag yellow eels Anguilla anguilla (L.), in streams where they exhibit cryptic life habits and hide in narrow cavities between rocks. We ... [more ▼]

Externally attached telemetry transmitters are unsuitable to tag yellow eels Anguilla anguilla (L.), in streams where they exhibit cryptic life habits and hide in narrow cavities between rocks. We evaluated the adequacy of surgical implantation and closing procedures for tagging eels with biotelemetry transmitters. Epoxy dummy transmitters (18_8 mm, 1.6–1.7 g) were implanted in eels anaesthetised with 2-phenoxy-ethanol (0.9 ml l−1), through a 20mm mid ventral incision made in the posterior quarter of their body cavity. The incision was either left open, or closed in different ways: stitches (absorbable or non absorbable suture material) or commercial-grade cyanoacrilate adhesive (LoctiteTM). Fish were stocked in a 4 m2 flow through tank (15–17 _C), controlled daily for mortality and weekly for evaluating the healing process. No transmitter was expelled over a 12-week period, even in eels with unclosed incisions, of which 50% healed within 28 days (t50). Regardless of the nature of the filament, suturing induced skin and muscle necrosis, caused significantly higher mortality rates (60% after 10 weeks) and paradoxically slowed down the healing rate (40 and 45 d, respectively). Cyanoacrilate suppressed the inflammatory response and granted higher survival rate (90%), but did not permit to speed up the closing process (t50 = 52 d), as eels actively bit and removed the adhesive within hours. This behaviour was suppressed when we applied a freshly cut fragment of the eel dorsal fin as a biological bandage over the drying cyanoacrilate. The adhesive remained in place for one to two days and permitted to substantially increase the healing rate (t50 = 15 d). These results substantiate the efficiency of surgery techniques for tagging eels with radio transmitters, at least for units of small weight and bulk. [less ▲]

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See detailbeta-lactamases as models for protein-folding studies
Vanhove, M.; Lejeune, Annabelle ULg; Pain, R. H.

in Cellular and Molecular Life Sciences : CMLS (1998), 54(4), 372-377

This review traces some of the key features of the folding of beta-lactamases and their relevance to the way proteins fold in general. Studies on the enzymes have highlighted the nature and role of ... [more ▼]

This review traces some of the key features of the folding of beta-lactamases and their relevance to the way proteins fold in general. Studies on the enzymes have highlighted the nature and role of equilibrium and transient condensed states. The kinetics of folding are multiphasic, and when monitored by acrylamide quenching of the tryptophan fluorescence, an early phase provides evidence for the transient accumulation of a nonnative intermediate involving burial of tryptophan in a nonpolar environment. Intermediate phases can be understood in terms of progressive folding of different parts of the molecule. The later, slow phases are associated with proline isomerization in the TEM-1 enzyme and, in its P167T mutant form, with isomerization from trans to cis of the E166 T167 peptide bond. Coupled with kinetic and X-ray crystallographic studies of the beta-lactamase from Staphylococcus aureus and its D179Q mutant, it appears that the final stage of folding is that of collapse and packing of the Omega-loop on to the main body of the protein. [less ▲]

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See detailActualites therapeutiques 1997-1998 (1). Seconde partie.
Scheen, André ULg

in Revue Médicale de Liège (1998), 53(9), 518-23

The most important drugs registered and/or launched in Belgium during the last year in the various disciplines of internal medicine will be briefly described. The originality of each molecule as well as ... [more ▼]

The most important drugs registered and/or launched in Belgium during the last year in the various disciplines of internal medicine will be briefly described. The originality of each molecule as well as its modalities of appropriate use in clinical practice will be stressed. This second part is devoted to drugs acting on infectious, rheumatoid, immunologic, oncologic and urogenital diseases. [less ▲]

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See detailIdentification of a fossil wood specimen in the Red Sandstone Group of Southwestern Tanzania: stratigraphical and tectonic implications.
Damblon, Freddy ULg; Gerrienne, Philippe ULg; Doutrelepont, Hughes et al

in Journal of African Earth Sciences (1998), 26

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See detailA method for identification of non-linear multi-degree-of-freedom systems
Dimitriadis, Grigorios ULg; Cooper, Jonathan E

in Proceedings of the Institution of Mechanical Engineers - Part G - Journal of Aerospace Engineering (1998), 212(4), 287-298

System identification methods for non-linear aeroelastic systems could find uses in many aeroelastic applications such as validating finite element models and tracking the stability of aircraft during ... [more ▼]

System identification methods for non-linear aeroelastic systems could find uses in many aeroelastic applications such as validating finite element models and tracking the stability of aircraft during flight flutter testing. The effectiveness of existing non-linear system identification techniques is limited by various factors such as the complexity of the system under investigation and the type of non-linearities present. In this work, a new approach is introduced which can identify multi-degree-of-freedom systems featuring any type of non-linear function, including discontinuous functions. The method is shown to yield accurate identification of three mathematical models of aeroelastic systems containing a wide range of structural non-linearities. [less ▲]

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See detailJean le Lydien, Caton, Varron et Servius
Rochette, Bruno ULg

in Byzantinische Zeitschrift (1998), 91(2), 471-474

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See detailRecommendations for the health economic analysis to be performed with a drug to be registered in prevention or treatment of osteoporosis
Dere, W; Avouac, B; Boers, M et al

in Calcified Tissue International (1998), 63

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See detailVingt ans de rénovation rurale en Belgique wallonne
Schmitz, Serge ULg; Christians, Charles ULg

in Cadernos de Geografia (1998), 17

The paper analyses the twenty years of rural development policy in Wallonia and looks for its impact in the countryside renewal.

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See detailInfluence Of The Mode Of Insertion Of Siv Peptides Into Membranes On The Structure Of Model Membrane As Studied By P-31 Nmr
Schanck, A.; Peuvot, J.; Brasseur, Robert ULg

in Biochemical and Biophysical Research Communications (1998), 250(1), 12-4

The influence on model membrane organization of a fusion peptide of SIV and of a nonfusogenic mutant of this peptide was examined by molecular modeling and by 31P NMR. The calculated mode of insertion of ... [more ▼]

The influence on model membrane organization of a fusion peptide of SIV and of a nonfusogenic mutant of this peptide was examined by molecular modeling and by 31P NMR. The calculated mode of insertion of the fusion peptide shows that it adopts an oblique orientation towards the lipid-water interface and that this fusion peptide induces a destabilization of the bilayer structure of multilamellar vesicles as evidenced by 31P NMR observations. The SIV mutant showing a more vertical insertion into lipid layers is unable to induce nonlamellar structures. This study reinforces the correlation between fusogenic activity, induction of structures not organized in extended bilayers, and calculated mode of insertion of peptides into lipid layers. [less ▲]

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See detailMinimum standards in diagnosis and treatment of osteoporosis
Russell, AS; Recart, S; Reginster, Jean-Yves ULg et al

in Journal of Rheumatology (1998), 25(8), 1634-1637

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See detailProposal of boundaries for subdivision of the Famennian Stage: miospore implications.
Streel, Maurice ULg; Loboziak, S

in Newsletter. Subcommission on Devonian Stratigraphy (1998), 15

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See detailCharacterizations by automorphism groups of some rank 3 buildings - I. Some properties of half strongly-transitive triangle buildings
Van Maldeghem, H.; Van Steen, Kristel ULg

in Geometriae Dedicata (1998), 73(2), 119-142

In a sequence of papers, we will show that the existence of a (half) strongly-transitive automorphism group acting on a locally finite triangle building Delta forces Delta to be one of the examples ... [more ▼]

In a sequence of papers, we will show that the existence of a (half) strongly-transitive automorphism group acting on a locally finite triangle building Delta forces Delta to be one of the examples arising from PSL3(K) for a locally finite local skewfield K. Furthermore, we introduce some Moufang-like conditions in affine buildings of rank 3, and characterize those examples arising from algebraic,classical or mixed type groups over a local field. In particular, we characterize the p-adic-like affine rank 3 buildings by a certain p-adic Moufang condition, and show that such a condition has zero probability to survive in hyperbolic rank 3 buildings. This shows that a construction of hyperbolic buildings as analogues of p-adic affine buildings is very unlikely to exist. Mathematics Subject Classifications (1991): 51E24, 51C05. [less ▲]

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See detailCrystal structures of the psychrophilic a-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor
Aghajari, N.; Feller, Georges ULg; Gerday, Charles ULg et al

in Protein Science : A Publication of the Protein Society (1998), 7(6), 564-572

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See detailDemonstration of the expression of CD95 ligand transcript and protein in human placenta
Zorzi, Willy ULg; Thellin, Olivier ULg; Coumans, Bernard ULg et al

in Placenta (1998), 19(4), 269-277

Tolerance of the fetal allograft enables the human conceptus to implant itself into the maternal uterus and survive and grow there. This tolerance phenomenon remains largely obscure, notably because it ... [more ▼]

Tolerance of the fetal allograft enables the human conceptus to implant itself into the maternal uterus and survive and grow there. This tolerance phenomenon remains largely obscure, notably because it appears to be controlled by multiple mechanisms. CD95 ligand (CD95-L), which can trigger death of CD95-positive cells by apoptosis, may participate in inducing anti-fetus-sensitized CD95-positive T lymphocytes to enter apoptosis. Using immunohistochemistry (first trimester and term placentae), FAGS assays (term placenta) and RT-PCR assays (term placenta), the presence of CD95-L protein and mRNA has been shown in crude placental tissue preparations and isolated placental cells. Among the latter, CD95-L expression was detected in trophoblastic cells, fetal blood cells (mRNA only) and also the Hofbauer macrophages. No CD95-L was detected in fibroblasts or fetal endothelial cells. Thus trophoblastic cells, Hofbauer macrophages, and perhaps also fetal blood cells could form a sequential barrier blocking maternal activated defence cells bearing CD95 molecules. (C) 1998 W. B. Saunders Company Ltd. [less ▲]

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See detailSuccessful Bridge to Transplantation with Pierce Donachy (Thoratec) Ventricular Assist Device
DEFRAIGNE, Jean ULg; DETRY, Olivier ULg; Demoulin, J.C. et al

in Acta Chirurgica Belgica (1998), 98(2), 90-4

Biventricular assistance with the Thoratec ventricular assist device was performed in a 48-year-old man waiting heart transplantation since 6 months. Indication for circulatory support was considered ... [more ▼]

Biventricular assistance with the Thoratec ventricular assist device was performed in a 48-year-old man waiting heart transplantation since 6 months. Indication for circulatory support was considered because of the development of progressive irreversible right heart failure with deterioration of the hepatic and renal functions. Orthotopic heart transplantation was performed after 13 days of circulatory support. No complications occurred during the assistance and in the posttransplant period. The patient was discharged on day 21 after transplantation. Five months after transplantation he is well and alive. [less ▲]

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See detailChorologie et écologie de Pycnoporus Cinnabarinus (Polyporaceae) en Belgique, au Grand-Duché de Luxembourg et dans les régions limitrophes
Thoen, Daniel ULg; Fraiture, A.; Nicolas, Jacques ULg

in Belgian Journal of Botany (1998), 131(2), 260-272

L'extension récente, après 1960, de Pycnoporus cinnabarinus, en Belgique, au Grand-Duché de Luxembourg et dans les régions limitrophes est analysée à l'aide d'une série chronologique de cartes de ... [more ▼]

L'extension récente, après 1960, de Pycnoporus cinnabarinus, en Belgique, au Grand-Duché de Luxembourg et dans les régions limitrophes est analysée à l'aide d'une série chronologique de cartes de distribution. La propagation du champignon semble s'être effectuée à deux "vitesses" : par bonds, sur des distances de plusieurs dizaines de kilomètres, et de proche en proche, au départ de populations voisines. L'analyse de la fréquence et de la fréquence cumulée des récoltes montre deux grandes "vagues" successives d'expansion du champignon. La liste des arbres hôtes est établie ainsi que la fréquence relative du champignon en fonction des hôtes. Les hôtes les plus fréquents sont les bouleaux (Betula alba et Betula pendula), le hêtre (Fagus sylvatica), le sorbier des oiseleurs (Sorbus aucuparia) et les chênes (Quercus robur et Quercus petraea). Les causes de l'extension et des fluctuations des populations du champignon ne sont pas connues avec certitude. Il semble cependant que des facteurs climatiques et le fait que de plus grandes quantités de bois pourrissant soient abandonnées sur les coupes puissent être impliqués. [less ▲]

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See detailCortical electrophysiology in migraine and possible pathogenetic implications
Schoenen, Jean ULg

in Clinical Neuroscience (New York, N.Y.) (1998), 5

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See detailEffects of Dobutamine on Isovolumic and Ejection Phase Indices of Cardiac Contractility in Conscious Healthy Dogs
Mc Entee, Kathleen ULg; Amory, Hélène ULg; Pypendop, B. et al

in Research in Veterinary Science (1998), 64(1, Jan-Feb), 45-50

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was ... [more ▼]

The aim of this study was to determine cardiac contractility using indices derived from cardiac catheterisation in conscious healthy dogs during dobutamine infusion. Eight dogs were studied. An ECG was recorded together with left ventricular pressure and volume which were measured using a conductance catheter with an integrated microtip pressure sensor. Eight indices of left ventricular systolic performance were derived from these records. Measurements were realised under basal conditions and during an incremental dobutamine challenge. The maximal rate of rise in ventricular pressure (max dP/dt), max dP/dt divided by the developed pressure and the mean systolic ejection rate were the most sensitive indices to detect dobutamine induced changes in contractility with maximal percentage changes of 122+/-11 per cent, 130+/-7 per cent and 102+/-24 per cent respectively. Ejection fraction increased significantly during dobutamine infusion (maximal percentage change of 43+/-9 per cent) whereas the pre-ejection period (PEP) and the left ventricular ejection time (LVET) decreased significantly (maximal percentage change of -41+/-2 per cent and -28+/-3 per cent respectively). All these six indices were significantly correlated with each other. Conversely, the ratio PEP/LVET and the LVET corrected for heart rate dependency showed a maximal percentage change of only -10+/-1 per cent and -16+/-7 per cent, respectively, during the dobutamine infusion and were not significantly correlated with the other contractility indices. This study demonstrated the feasibility of the conductance method to determine cardiac contractility in conscious healthy dogs submitted to a pharmacological stress testing and provides control values for eight indices of left ventricular contractility during dobutamine infusion at increasing dosages. [less ▲]

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See detailImmigrés et minorités ethniques dans l'espace politique européen
Martiniello, Marco ULg; Hily, M.-A.

in Revue Européenne des Migrations Internationales (1998), 14(2),

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See detailLes hypertensions artérielles d'origine endocrinienne.
Beckers, Albert ULg

in Tempo Médical (1998), 196

Les hypertensions artérielles d'origine endocrinienne représentent environ 3 à 5 % des hypertensions artérielles, parmi lesquelles les formes les plus sévères. Lors du diagnostic, une importance ... [more ▼]

Les hypertensions artérielles d'origine endocrinienne représentent environ 3 à 5 % des hypertensions artérielles, parmi lesquelles les formes les plus sévères. Lors du diagnostic, une importance particulière sera accordée à une sémiologie évocatrice. Une cause endocrinienne sera également activement recherchée dans les cas de mauvaises réponses au traitement classique de l'hypertension artérielle. [less ▲]

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See detailA novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns.
Singh, N. A.; Charlier, Carole ULg; Stauffer, D. et al

in Nature Genetics (1998), 18(1), 25-9

Idiopathic generalized epilepsies account for about 40% of epilepsy up to age 40 and commonly have a genetic basis. One type is benign familial neonatal convulsions (BFNC), a dominantly inherited disorder ... [more ▼]

Idiopathic generalized epilepsies account for about 40% of epilepsy up to age 40 and commonly have a genetic basis. One type is benign familial neonatal convulsions (BFNC), a dominantly inherited disorder of newborns. We have identified a sub-microscopic deletion of chromosome 20q13.3 that co-segregates with seizures in a BFNC family. Characterization of cDNAs spanning the deleted region identified one encoding a novel voltage-gated potassium channel, KCNQ2, which belongs to a new KQT-like class of potassium channels. Five other BFNC probands were shown to have KCNQ2 mutations, including two transmembrane missense mutations, two frameshifts and one splice-site mutation. This finding in BFNC provides additional evidence that defects in potassium channels are involved in the mammalian epilepsy phenotype. [less ▲]

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See detailLes mycoplasmes respiratoires des bovins : I. Clinique, diagnostic et traitement
Linden, Annick ULg; Thomas, A.; Mainil, Jacques ULg

in Annales de Médecine Vétérinaire (1998), 142

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See detailAtmungsmechanik beim Tier. 3. Mitteilung : Methodische und physiologische Aspekte bei der Anwendung des Impuls-Oszilloresistometrie-Systems (IOS)
Reinhold, Petra; Steinbach, Günther; Langenberg, Annelie et al

in Berliner und Munchener Tierarztliche Wochenschrift (1998), 111

The impulse oscillometry system (IOS) which was originally developed for human medicine was found to be suitable for analysing respiratory mechanics in spontaneously breathing animals. This technique is ... [more ▼]

The impulse oscillometry system (IOS) which was originally developed for human medicine was found to be suitable for analysing respiratory mechanics in spontaneously breathing animals. This technique is non-invasive. METHODOLOGICAL ASPECTS: In order to use the IOS-technique in animals, a tightly fitting face mask is necessary. Furthermore, a flexible tube needs to be inserted into the measuring system. While the tube does not influence the measured results significantly, the face mask may affect the measurements. Therefore, its influence on the measured respiratory impedance must be taken into account. To prevent methodological errors, the head and body position of the animal should be standardised during the IOS-measurement. Since the methodological variability of the system is very small, the measuring results are highly reproducible. PHYSIOLOGICAL ASPECTS: In growing subjects, all parameters of respiratory mechanics depend on body weight. Since respiratory physiology is influenced by circadian rhythms, measurements of different days are only comparable when they have been done each day at the same hour. Comparing the respiratory impedance of different animals of similar age and body weight, a considerable inter-individual variability was observed. Due to the low level of physiological intra-individual variability, the method seems to be especially useful for studying influences on the respiratory system (i.e. pharmaceutics, therapeutics) in long-term studies using the same group of subjects. [less ▲]

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See detailA Qtl Affecting Milk Yield and Composition Maps to Bovine Chromosome 20: A Confirmation
Arranz, J. J.; Coppieters, Wouter ULg; Berzi, P. et al

in Animal Genetics (1998), 29(2), 107-15

As part of a whole genome scan undertaken to detect quantitative trait loci (QTL) affecting milk yield and composition, we have genotyped a granddaughter design comprising 1152 sons for six microsatellite ... [more ▼]

As part of a whole genome scan undertaken to detect quantitative trait loci (QTL) affecting milk yield and composition, we have genotyped a granddaughter design comprising 1152 sons for six microsatellite markers spanning bovine chromosome 20. An analysis performed across families provided strong evidence (experiment-wise P-values < 0.01) for the presence of a QTL affecting primarily protein percentage towards the telomeric end of the chromosome. A founder sire, shown in a previous study to segregate for a similar QTL in the corresponding chromosome region, was characterized by 29 and 57 sons and maternal grandsons, respectively, in the present design. Sorting corresponding sons and grandsons by paternal or grandpaternal allele provided significant evidence for the segregation of a QTL on chromosome 20. Altogether these results confirm the location of a QTL affecting milk production on bovine chromosome 20. [less ▲]

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See detailLes associations radiochimiothérapiques dans les cancers du col utérin.
Maingon, Philippe; COUCKE, Philippe ULg; Haie-Meder, Catherine et al

in Cancer Radiotherapie (1998), 2

Le traitement des cancers du col utérin repose sur la radiothérapie et la chirurgie. Le pronostic des formes évoluées a conduit à proposer différentes modalités d’association dont seuls les traitements ... [more ▼]

Le traitement des cancers du col utérin repose sur la radiothérapie et la chirurgie. Le pronostic des formes évoluées a conduit à proposer différentes modalités d’association dont seuls les traitements concomitants ont montré un intérêt. Les associations de radiothérapie et d’un radiosensibilisant n’ont pas apporté, de bénéfice, voire abouti à des résultats inférieurs à ceux de l’irradiation exclusive. L’Hydroxyurée et la Mitomycine C ont été largement testées, seules ou en association, sans qu’elles puissent être retenues comme efficaces. Des associations modernes et des essais récents, il peut être établi que seul le Cisplatine (et peut-être ses dérivés) peut être retenu dans !es propositions thérapeutiques futures. 1998 Elsevier, Paris [less ▲]

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See detailTrophic relationships within intertidal communities of the Brittany coast: a stable carbon isotope analysis
Dauby, Patrick ULg; Khomsi, Ahmid; Bouquegneau, Jean-Marie ULg

in Journal of Coastal Research (1998), 14

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See detailPropofol reacts with peroxynitrite to form phenoxyl radicals. Demonstration by ESR
Mouithys-Mickalad, Ange ULg; Hans, Pol ULg; Deby-Dupont, Ginette et al

in Biochemical and Biophysical Research Communications (1998), 249(3), 833-837

Peroxynitrite (ONOO-), resulting from the reaction of nitric oxide with superoxide anion, is a powerful oxidant produced in activated macrophages, during ischemia-reperfusion processes as well as in ... [more ▼]

Peroxynitrite (ONOO-), resulting from the reaction of nitric oxide with superoxide anion, is a powerful oxidant produced in activated macrophages, during ischemia-reperfusion processes as well as in neurodegenerative disorders. This study investigated the reaction of the anesthetic agent propofol (PPF) with ONOO-, using electron spin resonance (ESR) and UV-visible spectrometry. Peroxynitrite was synthetized either from acidified hydrogen peroxide and nitrite, or from sodium azide and ozone. The addition of ONOO- to PPF in alkaline solution (pH 12) allowed to detect a, short lifetime, ESR signal corresponding to a phenoxyl radical. This finding was confirmed by a UV-visible study, resulting in the appearance of 427 nm peak and the disappearance of the peak located at 239 nm. The 291 nm peak remained unchanged. The identification of the end-product of the reaction of PPF with ONOO- needs further investigations. [less ▲]

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See detailTumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans.
Louis, Edouard ULg; Franchimont, D.; Piron, Anne ULg et al

in Clinical & Experimental Immunology (1998), 113(3), 401-406

TNF-alpha is involved in infectious and immuno-inflammatory diseases. Different individuals may have different capacities for TNF-alpha production. This might determine a predisposition to develop some ... [more ▼]

TNF-alpha is involved in infectious and immuno-inflammatory diseases. Different individuals may have different capacities for TNF-alpha production. This might determine a predisposition to develop some complications or phenotypes of these diseases. The aims of our study were to assess the inter-individual variability of TNF-alpha production and to correlate this variability to a single base pair polymorphism located at position -308 in TNF gene. We studied 62 healthy individuals. TNF-alpha production after LPS stimulation was evaluated using a whole blood cell culture model. The TNF gene polymorphism was studied by an allele-specific polymerase chain reaction. Other cytokines produced in the culture, soluble CD14 concentrations and expression of CD14 on blood cells were also measured. Among the 62 individuals, 57 were successfully genotyped. There were 41 TNF1 homozygotes and 16 TNF1/TNF2 heterozygotes. TNF-alpha production after LPS stimulation of whole blood cell culture was higher among TNF2 carriers than among TNFI homozygotes (929pg/ml (480-1473pg/ml) versus 521 pg/ ml (178-1307 pg/ml); P<0.05). This difference was even more significant after correction of TNF-alpha production for CD14 expression on blood cells. In conclusion, the single base pair polymorphism at position -308 in the TNF gene may influence TNF-alpha production in healthy individuals. [less ▲]

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See detailCommentaires sur les travaux du bureau ABC
Fecher-Bourgeois, Fabienne ULg

in Bulletin de Documentation du Ministère des Finances (1998), LVIIIè année, n°5(Septembre - octobre 1998),

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See detailContinuous and non-invasive study of brain oxygenation in the calf by near infrared spectroscopy
Pringle, John; Uystepruyst, C.; Art, Tatiana ULg et al

in Research in Veterinary Science (1998), 65

Near infrared spectroscopy (NIRS) was used to detect changes in brain oxygenation in five tranquilised calves that were placed on a hypoxic gas mixture (10 per cent O2/90 per cent N2) and hyperoxic gas ... [more ▼]

Near infrared spectroscopy (NIRS) was used to detect changes in brain oxygenation in five tranquilised calves that were placed on a hypoxic gas mixture (10 per cent O2/90 per cent N2) and hyperoxic gas mixture (30 per cent O2/70 per cent N2) for five minutes at each concentration. A NIRO 500 (Hamamatsu, Japan) was used for the NIRS, with the incident light source and separate detector (optodes) placed on shaved skin on the most dorsal surface of the frontal bone. Sequential arterial blood gas sample analyses provided confirmation of the appropriate change in systemic oxygenation status. By the end of the five-minute-period of breathing 10 per cent oxygen, NIRS of the calf head detected highly significant changes in haemoglobin oxygenation reflective of hypoxaemia, with oxyhaemoglobin decreasing by 23.5 units (P<0.01) and deoxyhaemoglobin increasing by 45.6 units, (P<0.01) from the baseline of breathing room air. Total haemoglobin (oxyhaemoglobin + deoxyhaemoglobin) showed a significant increase of 22.1 units (P<0.05) but there was no significant change in NIRS determined cytochrome aa3 oxygenation. Concomitant blood gas alterations included significant decreases in PaO2 (-27.8 mmHg, P<0.01), haemoglobin saturation (-29.0 per cent, P<0.05), and PaCO2 (-7.8 mmHg, P<0.05) and significantly increased blood pH (0.059, P<0.05). At the end of the five minutes of breathing 30 per cent oxygen NIRS of the calf head detected significantly increased oxyhaemoglobin (13.1 units, P<0.01) and decreased deoxyhaemoglobin (-13.7 units, P<0.05) when compared with baseline breathing of room aim. Total haemoglobin and cytochrome aa3 were unchanged from baseline. The accompanying arterial blood gas changes included significant increases in PaO2 (30.9 mmHg, P<0.05), arterial O2 saturation (11.7 per cent, P<0.05), and significantly decreased pH (-0.026, P<0.05). This study showed that NIRS can be used to continuously and non-invasively detect cerebral oxygenation changes in the live calf in response to both increased and decreased systemic arterial oxygen. Additionally, despite induction of profound hypoxaemia, cytochrome aa3 in the brain did not appear to become reduced. [less ▲]

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See detailHow the *H-particle* unravels the quark dynamics
Stancu, Floarea ULg; Pepin, S.; Glozman, L Ya

in Physical Review. D : Particles and Fields (1998), D57

It is shown that the short-range part of the Goldstone boson exchange interaction between the constituent quarks, which explains baryon spectroscopy and the short-range repulsion in the NN system, induces ... [more ▼]

It is shown that the short-range part of the Goldstone boson exchange interaction between the constituent quarks, which explains baryon spectroscopy and the short-range repulsion in the NN system, induces a strong short-range repulsion in the flavour-singlet state of the $S=-2$ system with $J^P=0^+$. This suggests that a deeply bound H-particle should not exist. We compare our approach with other models employing different hyperfine interactions between quarks in the nonperturbative regime of QCD. [less ▲]

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See detailStress coupling between earthquakes in Northwest Turkey and the North Aegean Sea
Nalbant, Süleyman; Hubert, Aurelia ULg; King, G. C. P.

in Journal of Geophysical Research (1998), 103

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See detailInfluence de facteurs abiotiques ou biotiques sur l'evaluation de la sensibilite d'Aphidius rhopalosiphi De Stefani-Perez a la phosalone.
Guelton, O.; Deleu, R.; Schiffers, Bruno ULg et al

in Parasitica (1998), 54(2-3),

MEAD-BRIGGS (1992) a proposé une méthode de laboratoire permettant d'évaluer la toxicité de contact d'un pesticide à l'égard d'Aphidius rhopalosiphi De Stefani-Perez, un parasitoïde des pucerons des ... [more ▼]

MEAD-BRIGGS (1992) a proposé une méthode de laboratoire permettant d'évaluer la toxicité de contact d'un pesticide à l'égard d'Aphidius rhopalosiphi De Stefani-Perez, un parasitoïde des pucerons des céréales. L'influence de l'humidité relative, de la photo période, du mode de conservation des momies ainsi que du sexe des insectes sur la sensibilité des parasitoïdes à la phosalone a été étudiée. L'humidité relative influence le plus la sensibilité des insectes lors des essais, le mode de conservation des momies se révèle important lui aussi. [less ▲]

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See detailLocalisation de la laminine, fibronectine, de la E-cadhérine et des intégrines dans l’endomètre et l’endométriose
BELIARD, Aude ULg; Donnez, J; Nisolle, Michelle ULg et al

in Reproduction Humaine et Hormones (1998), 2

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See detailLes territoires biogéographiques de la Belgique.
De Sloover, Jacques; Dufrêne, Marc ULg

in Acta geographica Lovaniensia (1998), 37

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See detailEvolution of the Peierls distortion in liquid AsxSb1-x compounds
Raty, Jean-Yves ULg; Gaspard, Jean-Pierre ULg; Céolin, R. et al

in Journal of Non-Crystalline Solids (1998), 232-234

The local order in the liquid binary alloy AsxSb1-x (0 ≤ x ≤ 1) is studied by short-wavelength (λ = 0.7 Å) neutron scattering. The coordination number (Z) and the interatomic distances (d) are analyzed in ... [more ▼]

The local order in the liquid binary alloy AsxSb1-x (0 ≤ x ≤ 1) is studied by short-wavelength (λ = 0.7 Å) neutron scattering. The coordination number (Z) and the interatomic distances (d) are analyzed in terms of the As concentration: Z increases continuously, from a value of 3.5 for pure arsenic to a value of 6.3 for pure antimony, whereas d shows a departure from Vegard's rule. The interatomic distance increases in the range 0.15 ≤ x ≤ 1.00 and is almost constant in the range 0.00 ≤ x ≤ 0.15. A simple tight-binding model is developed, which indicates that the relevant parameter is the hardness of the core repulsion between the atoms. © 1998 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailLatinitas-Peregrinitas. Purisme et nationalisme linguistique chez les grammairiens latins
Rochette, Bruno ULg

in Orbis : Bulletin international de documentation linguistique (1998), 40

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See detailFoaming properties of lipopeptides produced by Bacillus subtilis: effect of lipid and peptide structural attributes
Razafindralambo, Hary ULg; Popineau, Yves; Deleu, Magali ULg et al

in Journal of Agricultural and Food Chemistry (1998), 46(3), 911-916

To study the effect of lipid and peptide structural attributes of Bacillus subtilis lipopeptides on their foaming properties, the formation, stability, and appearance of foams prepared with surfactins ... [more ▼]

To study the effect of lipid and peptide structural attributes of Bacillus subtilis lipopeptides on their foaming properties, the formation, stability, and appearance of foams prepared with surfactins (C13 C15) and iturins A (C14 C17) were characterized. The density and stability of lipopeptide foams depend on both the alkyl chain hydrophobic character and peptide molecular intrinsic properties. A lipidic chain length of 14 carbon atoms provides lipopeptides with the best foaming properties in terms of foam density and liquid stability in foams. Increases in alkyl chain length above 15 carbon atoms result in a drastic decrease of iturin A foam density. With the same alkyl chain, surfactin produces denser foam whereas iturin A exhibits better foaming stability. These results demonstrate the importance of the peptide structural attributes of B. subtilis on their foaming properties. [less ▲]

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See detailL'apport des banques de données biogéographiques à la conservation de l'entomofaune
Lebrun, Philippe; Dufrêne, Marc ULg

in Parcs & Réserves (1998), 53

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