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See detailIntroduction to the objective arbitrability of corporate disputes in Belgium
Caprasse, Olivier ULg

in I.B.A. of A. Bulletin (2002)

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See detailCompte rendu de A. BRÄM, Das Andachtsbuch der Marie de Gavre
George, Philippe ULg

in Moyen Age (Le) (2002)

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See detailSubcellular Localization Of The Bovine Leukemia Virus R3 And G4 Accessory Proteins
Lefebvre, Laurent; Ciminale, Vincenzo; Vanderplasschen, Alain ULg et al

in Journal of Virology (2002), 76(15), 7843-7854

Bovine leukemia virus (BLV) is a complex retrovirus that belongs to the Deltaretrovirus genus, which also includes Human T-cell leukemia virus type 1 (HTLV-1). Both viruses contain an X region coding for ... [more ▼]

Bovine leukemia virus (BLV) is a complex retrovirus that belongs to the Deltaretrovirus genus, which also includes Human T-cell leukemia virus type 1 (HTLV-1). Both viruses contain an X region coding for at least four proteins: Tax and Rex, which are involved in transcriptional and posttranscriptional regulation, respectively, and the accessory proteins R3 and G4 (for BLV) and p12(I), p13(II), and p30(II) (for HTLV-1). The present study was aimed at characterizing the subcellular localization of BLV R3 and G4. The results of immunofluorescence experiments on transfected HeLa Tat cells demonstrated that R3 is located in the nucleus and in cellular membranes, as previously reported for HTLV-1 p12(1). In contrast, G4, like p13(II), is localized both in the nucleus and in mitochondria. In addition, we have shown that G4 harbors a mitochondrial targeting signal consisting of a hydrophobic region and an amphipathic alpha-helix. Thus, despite a lack of significant primary sequence homology, R3 and p12(1) and G4 and p13(II) exhibit similar targeting properties, suggesting possible overlap in their functional properties. [less ▲]

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See detailImpact of close habitat on the entomological diversity and abundance in carrot open fields.
Colignon, P.; Gaspar, Charles ULg; Haubruge, Eric ULg et al

in Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen (Rijksuniversiteit te Gent) (2002), 67(3), 481-6

Vegetable open fields areas have been increasing for the last decade in Wallonia (South part of Belgium), mainly in Hesbaye. To be in accordance with quality standards, especially in terms of agrochemical ... [more ▼]

Vegetable open fields areas have been increasing for the last decade in Wallonia (South part of Belgium), mainly in Hesbaye. To be in accordance with quality standards, especially in terms of agrochemical residues (R.M.L.), biological pest control was developed and reduces the insecticide use, leading to have safer fresh products. Carrot represents an important cultivated species in Wallonia. To asses the impact of close habitat on both pest (mainly aphids) and beneficial insects, carrot fields were investigated during all the production duration in 2000. Twelve fields between Waremme and Hannut were visited weekly from June to October. Insects were caught using yellow traps and determined to the family level. Approximately 90,000 insects belonging to 109 families were identified. Significant differences linked to field closed habitat were observed on 31 families. An increase of biodiversity in term of family number near set-asides and woody borders was observed. Evaluation of pest and beneficial diversity and density in vegetable crops was discussed to promote future IPM program. [less ▲]

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See detailDetermination of affinity, stoichiometry and sequence selectivity of minor groove binder complexes with double-stranded oligodeoxynucleotides by electrospray ionization mass spectrometry
Rosu, Frédéric ULg; Gabelica, Valérie ULg; Houssier, Claude ULg et al

in Nucleic Acids Research (2002), 30(16), 82

Electrospray mass spectrometry was evaluated regarding the reliability of the determination of the stoichiometries and equilibrium association constants from single spectra. Complexes between minor groove ... [more ▼]

Electrospray mass spectrometry was evaluated regarding the reliability of the determination of the stoichiometries and equilibrium association constants from single spectra. Complexes between minor groove binders (Hoechst 33258, Hoechst 33342, DAPI, netropsin and berenil) and 12mer oligonucleotide duplexes with a central sequence (A/T)(4) flanked by G/C base pairs were chosen as model systems. To validate the electrospray ionization mass spectrometry (ESI-MS) method, comparisons were made with circular dichroism and fluorescence spectroscopy measurements. ESI-MS allowed the detection of minor (2 drug + DNA) species for Hoechst 33258, Hoechst 33342, DAPI and berenil with duplex d(GGGG(A/T)(4)GGGG). d(CCCC(A/T)(4)CCCC), which were undetectable with the other techniques. Assuming that the duplexes and the complexes have the same electrospray response factors, the equilbrium association constants of the 1:1 and 2:1 complexes were determined by ESI-MS, and the values show a good quantitative agreement with fluorescence determined constants for Hoechst 33258 and Hoechst 33342. It is also shown that ESI-MS can quickly give reliable information on the A/T sequence selectivity of a drug: the signal of a complex is directly related to the affinity of the drug for that particular duplex. The potential of ESI-MS as a qualitative and quantitative affinity screening method is emphasized. [less ▲]

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See detailEveil des sociétés civiles en milieu urbain et organisations non gouvernementales: les exemples de Cotonou et de Lubumbashi
Pirotte, Gautier ULg; Poncelet, Marc ULg

in Autrepart : Revue de Sciences Sociales au Sud (2002), (23), 73-88

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See detailThe gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man
Marion, Evelyne; Kaisaki, Pamela Jane; Pouillon, Valérie et al

in Diabetes (2002), 51

Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and ... [more ▼]

Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and is thus a good candidate gene. Here we report the presence of SHIP2 gene mutations associated with type 2 diabetes in rats and humans. The R1142C mutation specifically identified in Goto-Kakizaki (GK) and spontaneously hypertensive rat strains disrupts a potential class II ligand for Src homology (SH)-3 domain and slightly impairs insulin signaling in cell culture. In humans, a deletion identified in the SHIP2 3' untranslated region (UTR) of type 2 diabetic subjects includes a motif implicated in the control of protein synthesis. In cell culture, the deletion results in reporter messenger RNA and protein overexpression. Finally, genotyping of a cohort of type 2 diabetic and control subjects showed a significant association between the deletion and type 2 diabetes. Altogether, our results show that mutations in the SHIP2 gene contribute to the genetic susceptibility to type 2 diabetes in rats and humans [less ▲]

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See detailEnzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
Fischle, Wolfgang; Dequiedt, Franck ULg; Hendzel, Michael J et al

in Molecular Cell (2002), 9(1), 45-57

Histone deacetylases (HDACs) play a key role in regulating eukaryotic gene expression. The HDAC domain, homologous to the yeast repressors RPD3 and HDA1, is considered necessary and sufficient for ... [more ▼]

Histone deacetylases (HDACs) play a key role in regulating eukaryotic gene expression. The HDAC domain, homologous to the yeast repressors RPD3 and HDA1, is considered necessary and sufficient for enzymatic activity. Here, we show that the catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor N-CoR/SMRT. All experimental conditions leading to the suppression of HDAC4 binding to SMRT/N-CoR and to HDAC3 result in the loss of enzymatic activity associated with HDAC4. In vitro reconstitution experiments indicate that HDAC4 and other class II HDACs are inactive in the context of the SMRT/N-CoR-HDAC3 complex and do not contribute to its enzymatic activity. These observations indicate that class II HDACs regulate transcription by bridging the enzymatically active SMRT/N-CoR-HDAC3 complex and select transcription factors independently of any intrinsic HDAC activity. [less ▲]

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See detailDes pratiques aux performances : la littératie chez les jeunes de 15 ans
Lafontaine, Dominique ULg

in Lettre de la DFLM (La) (2002), 30

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See detailUne dorsalgie malheureusement tenace
Malaise, Michel ULg; Kaye, Olivier; Radermecker, Maurice ULg et al

in Revue Médicale de Liège (2002), 57(5), 270-273

The etiological diagnosis of chronic thoracic pain is wide, from benign mechanical disorders to tumors. Reaching the exact diagnosis in often time consuming. Despite the availability of new techniques of ... [more ▼]

The etiological diagnosis of chronic thoracic pain is wide, from benign mechanical disorders to tumors. Reaching the exact diagnosis in often time consuming. Despite the availability of new techniques of imagery, a meticulous clinical history and physical examination remain mandatory. They will lead the exploration. Idiopathic intercostal neuralgia does not exist. [less ▲]

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See detailCharacterization of pregnancy-associated glycoproteins extracted from zebu (Bos indicus) placentas removed at different gestational periods
Melo de Sousa, Noelita ULg; Remy, Benoit; El Amiri, Bouchra et al

in Reproduction Nutrition Development (2002), 42(3), 1-15

In the present work, two biochemical approaches were used to characterize PAGs isolated from Bos indicus fetal cotyledons removed at different gestational ages. The first procedure included acidic and ... [more ▼]

In the present work, two biochemical approaches were used to characterize PAGs isolated from Bos indicus fetal cotyledons removed at different gestational ages. The first procedure included acidic and ammonium sulfate precipitations, anion and cation exchange chromatographies and the second included pepstatin-agarose affinity chromatography. A bovine PAG radioimmunoassay was used to monitor the immunoreactivity throughout the isolation procedures. The most immunoreactive fractions issued from cation exchange and affinity chromatographies were analyzed by SDS-PAGE and Western blotting, before transfer to a polyvinylidene difluoride (PVDF) membrane for NH2-microsequence determination. Use SDS-PAGE and Western blotting, different isoforms of PAG with apparent molecular masses of 51 to 69 kDa and isoelectric points varying from 4.4 to 6.7 were identified in the placentas from different gestational ages. N-terminal microsequencing (10 to 25 aa long) indicates the expression of one single terminal amino acid sequence in the Bos indicus placenta, which is 100% identical to the bovine PAG-1. [less ▲]

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See detailEcology of Salmonella in slaughter pigs digestive tract and study of the contamination of carcasses
Boudry, Christelle ULg; Korsak Koulagenko, Nicolas ULg; Jacob, Benoit et al

in Annales de Médecine Vétérinaire (2002), 146(6, DEC-JAN), 353-360

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal ... [more ▼]

This article presents a study on the Salmonella asymptomatic carriage of finishing pigs and its consequences on the contamination of carcasses. Twenty finishing pigs were followed to determine the faecal shedding of Salmonella. No sample was positive but at the slaughterhouse, the analysis of tonsils and certain parts of the digestive tract (mesenterial lymph nodes, ileum and large intestine content) revealed that 70% of the pigs were positive. The strains isolated from the faecal samples of the large intestine and from tonsils were identical, which might indicate that there has been an oral contamination from pig to pig due to the shedding of Salmonella or a carriage of different strains in different organs. The mesenterial lymph nodes (40 % positive) were contaminated by strains which were different from those from the faecal samples and tonsils. Salmonella strains were only found on the swabs of one carcass. A complementary assay has shown the negative role played by the scalding step. This latter may contaminate the oral and rectal cavities of slaughtered animals. This entire study reveals the difficulty to predict the contamination risk at the slaughterhouse from the analysis of finishing pigs faecal samples. Therefore, a better knowledge of the carriage and the shedding of Salmonella during the finishing period and during the slaughter is necessary to minimise meat contamination. [less ▲]

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See detailMR1905401,, Khan, A. R. and Elkamel, A., Mathematical model for heat transfer mechanism for particulate System, Appl. Math. Comput.
Rochus, Pierre ULg

in Applied Mathematics and Computation (2002), 129(2-3), 295--316

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See detailCharacterization Of Kenyan Isolates Of Fusarium Udum From Pigeonpea [Cajanus Cajan (L.) Millsp.] By Cultural Characteristics, Aggressiveness And Aflp Analysis
Kiprop, E. K.; Baudoin, Jean-Pierre ULg; Mwang'Ombe, A. W. et al

in Journal of Phytopathology-Phytopathologische Zeitschrift (2002), 150

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See detailPrediction of carcass lean content by real-time ultrasound in Piétrain and negative stress Piétrain
Youssao, A. K. L.; Verleyen, Vincent ULg; Leroy, Pascal ULg

in Animal Science (2002), 75

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See detail'Pretty Happy!'
Delville, Michel ULg

in Literary Review (2002), 46(1), 196-199

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See detailFlexihealth : une méthodologie d'évaluation du stress en situation de changement
De Zanet, Fabrice ULg; Vandenberghe, C.; Bossut, Muriel ULg et al

in Médecine du Travail & Ergonomie= Arbeidsgezondheidszorg & Ergonomie (2002), 39(2), 82-83

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See detailAspects de la conclusion du contrat par voie électronique
Biquet, Christine ULg; Decharneux, Joëlle ULg

in Actualités du Droit (2002)

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See detailIntranasal infusion of enilconazole for treatment of sinonasal aspergillosis in dogs.
Zonderland, Jean-Luc; Stork, Christoph; Saunders, Jimmy et al

in Journal of the American Veterinary Medical Association [=JAVMA] (2002), 221

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See detailEffects of incidental and intentional feature binding on recognition: a behavioural and PET activation study
Lekeu, Françoise ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Neuropsychologia (2002), 40(2), 131-144

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were ... [more ▼]

Using Positron Emission Tomography (PET), we investigated cerebral regions associated with the episodic recognition of words alone and words bound to contextual colours. Two modes of colour encoding were tested: incidental and intentional word-to-colour binding. Word-only recognition was associated with brain activation in a lexico-semantic left middle temporal region and in the cerebellum following an incidental colour encoding, and with brain activation in the left posterior middle frontal gyrus, right anterior cingulate and right inferior frontal gyrus following an intentional encoding. Recognition of bound features was associated with activation in left prefrontal and superior parietal regions following an incidental colour encoding, and with preferential right prefrontal cortex activation following an intentional colour encoding. Our results are in line with the hypothesis of a parietal involvement in context processing, and prefrontal areas in monitoring retrieval processes. Our results also support the hypothesis of a 'cortical asymmetry for reflective activity' (CARA). [less ▲]

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See detailDesign of a foil-coiled inductor for the heating of steel wires
De coster, Jeroen; Deliège, Geoffrey ULg; Henrotte, François et al

in IEE Proceedings - Science, Measurement & Technology (2002), 149(5), 203-206

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See detailLa critique historique: méthode ou théorie de l'histoire? Libres propos en faveur du constructivisme
Havelange, Carl ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2002), 94-95-96

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See detailA qui appartient le ragondin ?
Roussel, Laurence; Mougenot, Catherine ULg

in Espaces et Sociétés (Paris, France) (2002), (110-111), 225-247

La lutte contre le ragondin, espèce importée d'Amérique du Sud en Europe, aujourd'hui classée parmi les espèces invasives, a été inscrite simultanément dans deux législations différentes. Dans le ... [more ▼]

La lutte contre le ragondin, espèce importée d'Amérique du Sud en Europe, aujourd'hui classée parmi les espèces invasives, a été inscrite simultanément dans deux législations différentes. Dans le mondeagricole, c'est une action qui s'inspire de la guerre contre les ravageurs des cultures. Elle s'organise collectivement à l'aide d'un poison, la bromadiolone. Dans le monde de la chasse, elle est principalement du domaine des piégeurs. Solitaires, ceux-ci pourchassent le ragondin en tant qu'espèce nuisible. Cette division est héritée du Moyen Âge, de ses usages de l'espace et des droits qui leur étaient associés (droit de destruction pour les agriculteurs). Actuellement, l'espace rural peut être vu comme une mosaïque, òu ces deux principaux types de lutte coexistent, alors que certains milieux restent libres de toute intervention. Mais ces actions sont aussi l'objet de critiques qui mettent en cause l'utilisation de la bromadiolone et certaines formes de piégeage. Et aujourd'hui, on observe que les modalités de lutte contre le ragondin se combinent aux nouveaux usages de l'espace. [less ▲]

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See detailAutomatic time stepping algorithms for implicit numerical simulations of non-linear dynamics
Noels, Ludovic ULg; Stainier, Laurent ULg; Ponthot, Jean-Philippe ULg et al

in Advances in Engineering Software (2002), 33(7-10, JUL-OCT), 589-603

When an implicit integration scheme is used, variable step strategies are especially well suited to deal with problems characterized by high non-linearities. Constant step size strategies generally lead ... [more ▼]

When an implicit integration scheme is used, variable step strategies are especially well suited to deal with problems characterized by high non-linearities. Constant step size strategies generally lead to divergence or extremely costly computations. An automatic time stepping algorithm is proposed that is based on estimators of the integration error of the differential dynamic balance equations. Additionally, the proposed algorithm automatically takes decisions regarding the necessity of updating the tangent matrix or stopping the iterations, further reducing the computational cost. As an illustration of the capabilities of this algorithm, several numerical simulations of both academic and industrial problems are presented. (C) 2002 Civil-Comp Ltd and Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailAre all glitazones the same?
Van Gaal, Luc; Scheen, André ULg

in Diabetes/Metabolism Research & Reviews (2002), 18 Suppl 2

This supplement focuses on the benefits of targeting insulin resistance through therapy with a new class of oral antidiabetic agents, the thiazolidinediones (TZDs) or 'glitazones'. There are important ... [more ▼]

This supplement focuses on the benefits of targeting insulin resistance through therapy with a new class of oral antidiabetic agents, the thiazolidinediones (TZDs) or 'glitazones'. There are important differences between the three TZD class members that warrant discussion to enable physicians to make rational and informed therapeutic choices between the agents. Overall the TZDs appear to be similar in their effects on blood glucose, as all class members have demonstrated effective glycaemic control, both as monotherapy and in combination with sulphonylureas, metformin or exogenous insulin. The safety profiles of the three agents are more diverse, with what appear to be 'TZD class effects', (probably mediated via activation of peroxisome proliferator-activated receptor gamma [PPAR gamma]) and 'TZD-specific effects', which are unique to each agent and may be a consequence of differing chemical structures. While rosiglitazone and pioglitazone share some class effects with troglitazone, they have several characteristics that define them as unique agents. By tackling the control of type 2 diabetes through direct effects on insulin resistance, the TZDs represent an important new therapeutic tool for healthcare professionals. [less ▲]

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See detailComposition de la carcasse, qualité de viande et exploitation du Piétrain stress négatif
Youssao, A. K. L.; Verleyen, Vincent ULg; Michaux, Charles ULg et al

in Annales de Médecine Vétérinaire (2002), 146(6), 329-338

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See detailStunting may determine the severity of malaria-associated anemia in African children.
Verhoef, Hans; West, Clive E; Veenemans, Jacobien et al

in Pediatrics (2002), 110(4), 48

OBJECTIVE: Evidence from previous studies that malnourished children are protected against malaria is controversial. In individuals repeatedly exposed to malaria, immunity may develop first against severe ... [more ▼]

OBJECTIVE: Evidence from previous studies that malnourished children are protected against malaria is controversial. In individuals repeatedly exposed to malaria, immunity may develop first against severe disease, then against pyrogens, and last, against parasites. If this is true, this would suggest that reduced immune function that may exist in stunted children exacerbates the severity of malarial signs and symptoms, rather than the occurrence of parasitemia. On the other hand, several studies have suggested that malnourished children are protected to some degree against malaria. Our aim was to evaluate whether observational data support the hypothesis that nutritional inadequacies that cause stunting modify the associations between malaria and hematologic indicators such as hemoglobin concentration and serum concentrations of C-reactive protein and soluble transferrin receptor (sTfR). We showed earlier that increased serum concentrations of these receptors in asymptomatic malaria may be explained, at least in part, by increased erythropoiesis to compensate for malaria-induced hemolysis. METHODOLOGY: Community-based cluster survey among Kenyan children aged 2 to 36 months asymptomatic for malaria or anemia (n = 318). RESULTS: When adjusted for age and wasting, the malaria-associated decrease in mean hemoglobin concentration was 8.5 g/L and 15.8 g/L in nonstunted and stunted children, respectively. The malaria-associated increase in geometric mean serum concentrations of sTfR was 1.1-fold and 1.8-fold in nonstunted and stunted children, respectively. The malaria-associated increase in geometric mean serum concentrations of C-reactive protein was 1.4-fold and 2.3-fold in nonstunted and stunted children, respectively. Thus, children with malaria and those who were stunted suffered from more severe anemia and had higher serum concentrations of C-reactive protein and sTfR than would be expected from the combined effect of the 2 working independently. CONCLUSIONS: Our results are consistent with the notion that the nutritional inadequacies causing stunting also impair host immunity, thus increasing the degree to which malaria is associated with decreased concentrations of hemoglobin, with increased inflammation, and with increased iron demand in developing erythroblasts. Increased intake of micronutrients may not only reduce stunting and nutritional anemia, but also reduce malaria-associated anemia. [less ▲]

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See detailRenouvellement des pédagogies musicales. Analyse et développement des innovations dans les cours d'instruments semi-collectifs
Giot, Bernadette ULg; Grifnée, Catherine

in Site du Ministère de la Communauté française de Belgique (2002)

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See detailEuropean guidelines for the management of low back pain
Van Tulder, M.; Kovacs, F.; Müller, G. et al

in Acta Orthopaedica Scandinavica. Supplement (2002), 73((Suppl 305)), 20-25

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See detailTexture evolution during deep-drawing processes
Duchene, Laurent ULg; Godinas, A.; Cescotto, Serge ULg et al

in Journal of Materials Processing Technology (2002), 125-126

This paper presents a constitutive law based on Taylor’s model implemented in our non-linear finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method ... [more ▼]

This paper presents a constitutive law based on Taylor’s model implemented in our non-linear finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method has been developed. This local yield locus model uses a discrete representation of the material’s texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture evolution during forming processes. [less ▲]

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See detailAnalysis of variables related to intrinsic motivation in a boys’ physical education class
Cloes, Marc ULg; Motter, Pascale; Ledent, Maryse ULg et al

in AVANTE (2002), 8(1), 1-14

In physical education settings, the development of intrinsic motivation in students is a central concern for every teacher. However, most studies have focused on isolated variables using quantitative ... [more ▼]

In physical education settings, the development of intrinsic motivation in students is a central concern for every teacher. However, most studies have focused on isolated variables using quantitative approaches. The purpose of this study was to underline the existence of relationships between students’ intrinsic motivation (assessed by dispositional factors) and individual/collective situational factors. A secondary school boys’ class and its teacher were the subjects of the study. Questionnaires and interviews were used. Data were initially processed from the class point of view. Based on a cluster analysis determined by intrinsic motivation level, two groups of students were compared. Qualitative analysis was based on the answers of the two most and the two least motivated students of the class. Extracurricular practice (individual situational variable), teacher-students’ interaction and mastery climate (collective situational variables) were identified among the factors related to students’ intrinsic motivation. Inter-individual diversity of influencing variables was pointed out. [less ▲]

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See detailBiospheric carbon stocks reconstructed at the Last Glacial Maximum: comparison between general circulation models using prescribed and computed sea surface temperatures
Otto, D.; Rasse, Daniel; Kaplan, J. et al

in Global and Planetary Change (2002), 33(1-2), 117-138

The terrestrial biosphere model Carbon Assimilation in the Biosphere (CARAIB) was improved by introducing two vegetation storeys and implementing a new module which simulates the equilibrium distribution ... [more ▼]

The terrestrial biosphere model Carbon Assimilation in the Biosphere (CARAIB) was improved by introducing two vegetation storeys and implementing a new module which simulates the equilibrium distribution of the vegetation inferred from physiological processes and climatic constraints. In this fourth version of CARAIB, we differentiate ground-level grasses from tree canopies, which allows us to determine the light available to grasses as a direct function of the leaf area index (LAI) of the forest canopy. Both of these storeys are potentially composed of several plant functional types (PFT). The cover fraction of each PFT within each storey is estimated according to its respective net primary productivity (NPP). A biome is assigned to each grid cell on the basis of three physiological criteria: (1) the cover fraction, (2) the NPP, and (3) the LAI; and two climatic constraints: (1) the growing degree-days (GDD) and (2) the lowest temperature reached during the cold season (T-min), which are well-known indices of vegetation expansion boundaries. Total biospheric carbon stocks (vegetation + soil) are reconstructed by forcing the model with eight climatic scenarios of the Last Glacial Maximum (LGM, 21 ka BP), which were obtained from the Palco-Modelling Intercomparison Project (PMIP) from four general circulation models (MRI2, UGAMP, LMD4, and GEN2) using prescribed and computed sea surface temperatures (SSTs). The model was also forced with a current climate together with a preindustrial atmospheric CO2 level of 280 ppm as reference simulation, To validate the model, current biome distribution is reconstructed and compared, for the modem climate, with two distributions of potential vegetation and, for the LGM, with pollen data. The model simulations are in good agreement with broad-scale patterns of vegetation distribution, The results indicate an increase in the total biospheric carbon stock of 827.8-1106.1 Gt C since the LGM. Sensitivity analyses were performed to discriminate the relative effects of the atmospheric CO, level ("fertilization effect"), the climate (present or LGM), and the sea level. Our results suggest that the CO, fertilization effect is mostly responsible for the total increase in vegetation and soil carbon stocks. The four GCMs diverged in their predicted responses of continental climate to calculated SSTs. Only one of them, i.e., MRI2, predicted a marked decline of the continental temperatures in response to lower calculated SSTs. For this GCM, the effect of reduced SSTs on continental biospheric carbon stocks was a decrease of 544.1 Gt for the soil carbon stock and of 283.7. [less ▲]

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See detailInteraction of an odorant lactone with model phospholipid bilayers and its strong fluidizing action in yeast membrane.
Aguedo, Mario ULg; Beney, Laurent; Wache, Yves et al

in International journal of food microbiology (2002), 80(3), 211-5

Some odorant lactones are naturally present in fruits or in fermented products; they can also be used as food additives and can be produced by microorganisms at the industrial scale by biotechnological ... [more ▼]

Some odorant lactones are naturally present in fruits or in fermented products; they can also be used as food additives and can be produced by microorganisms at the industrial scale by biotechnological processes. Gamma-decalactone was previously shown to have antimicrobial properties. We determined by infrared spectroscopy measurements that this compound rapidly diffused into model phospholipid bilayers (within 2 min), modifying the general physical state of a dimyristoyl-L-alpha-phosphatidylcholine (DMPC) film. In vivo, the lactone strongly increased membrane fluidity in the model yeast Yarrowia lipolytica, as evaluated by fluorescence anisotropy measurements. This effect was more important than that of benzyl alcohol, which is known as a fluidizing agent in living cells, and may explain the toxic action of gamma-decalactone in microorganisms. [less ▲]

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See detailMemory kernels and effective Hamiltonians from time dependent methods. II. Vibrational predissociation
Brems, Vincent; Desouter, Michèle ULg

in Journal of Chemical Physics (2002), 116

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See detailLe traitement de la phraséologie dans DEFI
Michiels, Archibal ULg

in Linguistica Antverpiensia (2002)

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See detailLes frais supportés par l'adjudicataire en cas de saisie-exécution immobilière
Georges, Frédéric ULg

in Journal des Tribunaux (2002)

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See detailA transformed fish cell line expressing a green fluorescent protein-luciferase fusion gene responding to cellular stress
Molina, A.; Carpeaux, Rudy ULg; Martial, Joseph ULg et al

in Toxicology in Vitro (2002), 16(2), 201-7

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein ... [more ▼]

We obtained a stable transformed fish (EPC) cell line containing a reporter gene under the control of the tilapia HSP70 promoter. Expression of the reporter gene, coding for a green fluorescent protein (GFP)-luciferase fusion protein, was assessed by measuring the luciferase enzymatic activity by luminometry and the GFP expression by fluorescence microscopy and flow cytometry. The clone was characterized for its capacity to respond to heat shock treatment. The results show high induction after 1 h at 37 degrees C of treatment, up to 500-fold. In addition, its convenience to detect a large range of cellular stressors was evaluated. We observed high induction when Cd2+, Zn2+, Hg2+ or Cu2+ was added, but not Pb2+. In addition, activation of the reporter gene was observed in the presence of other compounds such as acetyl chloride, tetrachlorophenol, chloroacetamide and sodium arsenite. In conclusion, this cell line can be used as a rapid, cheap and easy biological test to determine cellular stress induced by environmental pollutants, alone or in conjunction with other, more specific assays. [less ▲]

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See detailUtilisation du bootstrap pour les problèmes statistiques liés à l'estimation des paramètres.
Palm, Rodolphe ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2002), 6(3),

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See detailIn situ dynamic analysis of solid or aqueous solutions undergoing chemical reactions by RBS or PIXE with external beam
Bouquillon, A.; Dran, J*-C; Lagarde, G. et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2002), 188

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See detailLes acquis des jeunes de 15 ans en sciences : des progrès restent à faire...
Lafontaine, Dominique ULg; Burton, Réginald

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 9-10

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See detailImage du mois. Une tumeur préauriculaire.
Tassoudji, Nazli ULg; Nikkels, Arjen ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2002), 57(2), 65-66

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See detailEcueils et chausse-trapes.
Kulbertus, Henri ULg; Scheen, André ULg

in Revue Médicale de Liège (2002), 57(5), 249

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See detailThe multivariate Dale model and genetic associations
Van Steen, Kristel ULg; Molenberghs, G.; Tahri, N.

in American Journal of Human Genetics (2002), 71

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See detailOptimization of recombinant human erythropoietin therapy after allogeneic hematopoietic stem cell transplantation.
Baron, Frédéric ULg; Sautois, Brieuc ULg; Baudoux, Etienne ULg et al

in Experimental hematology (2002), 30(6), 546-54

OBJECTIVE: Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with prolonged anemia caused by defective erythropoietin (Epo) production. We enrolled 34 recipients of an allogeneic ... [more ▼]

OBJECTIVE: Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with prolonged anemia caused by defective erythropoietin (Epo) production. We enrolled 34 recipients of an allogeneic HSCT in three consecutive trials to determine the optimal utilization of recombinant human erythropoietin (rhEpo) therapy in this setting. MATERIALS AND METHODS: In the first trial (n = 7), rhEpo 1400 U/kg/week was given from day 1 until a hemoglobin (Hb) level of 10 g/dL was achieved, for a maximum of 60 days. In the second trial, rhEpo 500 U/kg/week was given to achieve Hb levels of 13 to 14 g/dL in 13 anemic patients with fatigue 56 to 1440 days after transplant. In the third trial, rhEpo was scheduled to start on day 35 in 14 patients at a dose of 500 U/kg/week with the aim of achieving Hb levels of 13 to 14 g/dL. RESULTS: In trial 1, erythroid recovery to 1% reticulocytes and red blood cell transfusion independence were faster, but the number of transfusions was not reduced compared to 10 controls. Responses were brisk in trial 2, with transfusion independence achieved after a median of 1 week in 12 of 13 patients, and 2-g Hb increments or Hb values of 11, 12, and 13 g/dL after 6, 7, 10, and 10 weeks, respectively. Transfusions were significantly reduced in the first month of rhEpo therapy. In trial 3, transfusion independence was obtained after a median of 1 week in 13 of 14 patients, and 2-g Hb increments or Hb values of 11, 12, and 13 g/dL after 3, 4, 6, and 8 weeks, respectively. Transfusions rates were considerably reduced compared to the previous month in the same patients or compared to controls undergoing peripheral blood or marrow transplant without rhEpo. CONCLUSIONS: Anemia after allogeneic HSCT is exquisitely sensitive to rhEpo. The benefit is minimal when it is given early post-transplant, as used in all trials to date. However, the rate of major response is greater than 90% when rhEpo is started after day 35. These data provide the basis on which to conduct a prospective, randomized, placebo-controlled trial of rhEpo therapy after allogeneic HSCT. [less ▲]

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See detailEvolution des donnees maternelles et perinatales recueillies en routine entre 1980 et 1998 a la maternite de reference de Rutshuru en Republique democratique du congo. Deces maternels et interventions obstetricales.
Mugisho, Etienne; Dramaix, Michele; Porignon, Denis ULg et al

in Sante (Montrouge, France) (2002), 12(2), 247-51

This report is the first of 2 papers that analyse data routinely collected in the maternity ward of Rutshuru (democratic Republic of Congo). The present work describes the evolution of caesarean section ... [more ▼]

This report is the first of 2 papers that analyse data routinely collected in the maternity ward of Rutshuru (democratic Republic of Congo). The present work describes the evolution of caesarean section, maternal deaths and the associated risk factors. MATERIAL AND METHODOLOGY: Between 1980 and 1998, data on 13,042 deliveries were collected. Characteristics, mortality, morbidity of mothers and new-borns and obstetrical interventions were recorded. The statistical analyses applied included khi2, t-test, simple linear and multiple logistic regression. RESULTS: Fifteen percent had a caesarean section and 1.9% of women died. When referred to the expected births during the period, these numbers led to a ratio of 150 maternal deaths for 100,000 expected births and a ratio of caesarean section of 1.2%. At admission, 35% of the women presented at least one of the four risk factors used for reference. The proportion of women with at least one of the 4 risk factors went up from 26.1% to 39.5%. The proportion of caesarean sections went up from 1.9% to 34.1%. The proportion of maternal deaths remained constant except in 1988, 1994, 1995 and 1997. Three of the four reference factors, the Baudeloque diameter, parity and height were associated with caesarean section. Age only was associated with maternal death. Education and marital status were both associated with caesarean section and maternal death. CONCLUSION: This analysis shows high levels of maternal mortality and caesarean section. The authors recommend to analyse on a larger scale the value of the reference factors used in antenatal services and to standardise indications for the different obstetrical interventions. [less ▲]

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See detailNew Basic Membrane-Destabilizing Peptides For Plasmid-Based Gene Delivery In Vitro And In Vivo
Rittner, K.; Benavente, A.; Bompard-Sorlet, A. et al

in Molecular Therapy (2002), 5(2), 104-14

We have designed new basic amphiphilic peptides, ppTG1 and ppTG20 (20 amino acids), and evaluated their efficiencies in vitro and in vivo as single-component gene transfer vectors. ppTG1 and ppTG20 bind ... [more ▼]

We have designed new basic amphiphilic peptides, ppTG1 and ppTG20 (20 amino acids), and evaluated their efficiencies in vitro and in vivo as single-component gene transfer vectors. ppTG1 and ppTG20 bind to nucleic acids and destabilize liposomes consisting of 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) and cholesterol (3:1 mol/mol) at pH 5 and pH 7. Complexes of plasmid DNA and ppTG1 gave rise to efficient transfection in a variety of human and murine cell lines at low charge ratios ([+/-] between 1 and 2). In cell culture experiments, such vectors were superior to the membrane-destabilizing peptide KALA. In comparison with cationic lipid-, dendrimer-, and polymer-based transfection agents like Superfect, polyethylenimine (PEI), and Lipofectin, ppTG1 vectors showed good transfection efficiencies, especially at low DNA doses. Moreover, we demonstrated for the first time successful gene transfer in living animals with a single-component peptide vector. In the mouse, intravenous injection of a luciferase expression plasmid complexed with ppTG1 or ppTG20 led to significant gene expression in the lung 24 hours after injection. Structure-function studies with ppTG1, ppTG20, and sequence variants suggest that the high gene transfer activity of these peptides is correlated with their propensity to exist in alpha-helical conformation, which seems to be strongly influenced by the nature of the hydrophobic amino acids. [less ▲]

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See detailIn vivo manganese-enhanced magnetic resonance imaging reveals connections and functional properties of the songbird vocal control system
Van der Linden, A.; Verhoye, M.; Van Meir, V. et al

in Neuroscience (2002), 112(2), 467-474

Injection of manganese (Mn2+), a paramagnetic tract tracing agent and calcium analogue, into the high vocal center of starlings labeled within a few hours the nucleus robustus archistriatalis and area X ... [more ▼]

Injection of manganese (Mn2+), a paramagnetic tract tracing agent and calcium analogue, into the high vocal center of starlings labeled within a few hours the nucleus robustus archistriatalis and area X as observed by in vivo magnetic resonance imaging. Structures highlighted by Mn2+ accumulation assumed the expected tri-dimensional shape of the nucleus robustus archistriatalis and area X as identified by classical histological or neurochemical methods. The volume of these nuclei could be accurately calculated by segmentation of the areas highlighted by Mn2+. Besides confirming previously established volumetric sex differences, Mn2+ uptake into these nuclei revealed new functional sex differences affecting Mn2+ transport. A faster transport was observed in males than in females and different relative amounts of Mn2+ were transported to nucleus robustus archistriatalis and area X in males as compared to females. This new in vivo approach, allowing repeated measures, opens new vistas to study the remarkable seasonal plasticity in size and activity of song-control nuclei and correlate neuronal activity with behavior. It also provides new insights on in vivo axonal transport and neuronal activity in song-control nuclei of oscines. (C) 2002 IBRO. Published by Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailConfirmation des effets délétères rénaux des AINS anti COX2 illustrée par trois cas cliniques
Piront, P.; Krzesinski, Jean-Marie ULg

in Acta Clinica Belgica (2002), 57(1), 35

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See detailEtalonnage de la figure complexe de Rey sur une population d’enfants de six à douze ans
Garcet, Serge ULg; Deltour, Jean-Jacques; Remacle, Michel

in Revue Scientifique de l'AIGS (2002), 1

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See detailLe dépassement du délai raisonnable en matière d'infraction à la législation sur les douanes et accises
Monville, Pierre ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2002)

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See detailPredicting transpiration from forest stands in Belgium for the 21st century
Misson, Laurent; Rasse, Daniel; Vincke, Caroline et al

in Agricultural and Forest Meteorology (2002), 111(4), 265-282

Canopy transpiration is a major element of the hydrological cycle of temperate forests. Levels of water stress during the 21st century will be largely controlled by the response of canopy transpiration to ... [more ▼]

Canopy transpiration is a major element of the hydrological cycle of temperate forests. Levels of water stress during the 21st century will be largely controlled by the response of canopy transpiration to changing environmental conditions. One year of transpiration measurement in two stands (Quercus robur L. and Fagus sylvatica L.) was used to calibrate the ASPECTS model on a(1) and D-0, two parameters of a modified version of Leuning's equation of stomatal conductance. A second year of data was used to validate the model. The results indicate a higher sensitivity of g(sc), to vapour pressure deficit (DS) in oak than in beech (D-0 (oak) < D-0 (beech)). To simulate future forest transpiration, site specific weather data sets were constructed from GCM outputs, spatially and temporally downscaled with local climatic data. Temperature increase between the end of the 20th and 21st centuries was predicted to be 2.8 degreesC in the beech stand and 3.1 degreesC in the oak stand. Based solely on temperature change, ASPECTS predicted an increase in transpiration of 17% in the beech and 6% in the oak stand, the difference being due to variation in local climate and the sensitivity of both species to D-s. Based solely on increased atmospheric CO2 (355 ppm in 1990 to 700 ppm in 2100), ASPECTS predicted that transpiration would decrease by 22% in beech and 19% in oak. With the combined scenarios of climatic change and increased atmospheric CO2, ASPECTS showed a decrease of 7% in transpired water in the oak stand and only 4% in the beech stand, which are not significant differences from zero. Consequently, water stress should not increase in either stand during the 21st century. (C) 2002 Elsevier Science B.V All rights reserved. [less ▲]

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See detailAdvantages and disadvantages of a control programme against infectious bovine rhinotracheitis in Belgium
Limbourg, B.; Kerkhofs, P.; Massard, C. et al

in Annales de Médecine Vétérinaire (2002), 146(2, APR-MAY), 57-69

A working party of the "Association d'Epidemiologie et de Sante Animale" assessed the strategy for a control of infectious bovine rhinotracheitis (IBR) in Belgium and studied its feasability and the ... [more ▼]

A working party of the "Association d'Epidemiologie et de Sante Animale" assessed the strategy for a control of infectious bovine rhinotracheitis (IBR) in Belgium and studied its feasability and the different programmes to be applied. Epidemiology of IBR in Belgium, vaccination, diagnostic methods, economic aspects of IBR control, Belgian laws regarding IBR and the motivation of people in the field were described. The advantages and disadvantages of three programmes were analysed: to maintain the current situation, to protect cattle against clinical disease and to control and eradicate IBR. [less ▲]

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See detailKinetic study of the acid hydrolysis of various oligofructose samples
Blecker, Christophe ULg; Fougnies, C.; Van Herck, J. C. et al

in Journal of Agricultural and Food Chemistry (2002), 50(6), 1602-1607

The kinetic of acid hydrolysis of five commercially available oligofructose samples used as food ingredients has been investigated as a function of the dry matter concentration, reaction pH, and ... [more ▼]

The kinetic of acid hydrolysis of five commercially available oligofructose samples used as food ingredients has been investigated as a function of the dry matter concentration, reaction pH, and temperature. The initial fructose release rate is found to be roughly proportional to the inverse of the average polymerization degree in number. A pseudo first order kinetic is found with respect to the fructosyl chain end concentration and to the proton concentration. Arrhenius plot is found to reasonably fit the data in a relatively wide temperature range (7-130 degreesC). The results allow the estimation of the fructose release rate in many foodstuff processing conditions. [less ▲]

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See detailFécondité de la vache Borgou au Bénin : effet de l'âge au premier vêlage sur l'intervalle entre vêlages
Adamou-N'Diaye, M.; Gbangboche, A. B.; Ogodja, O. J. et al

in Revue d'Elévage et de Médecine Vétérinaire des Pays Tropicaux (2002), 55(2), 1-5

Des données recueillies à la ferme du monastère de Kokoubou (département du Borgou au Bénin) ont servi à étudier l’âge au premier vêlage et l’intervalle entre vêlages chez la vache Borgou. De 1967 à 1989 ... [more ▼]

Des données recueillies à la ferme du monastère de Kokoubou (département du Borgou au Bénin) ont servi à étudier l’âge au premier vêlage et l’intervalle entre vêlages chez la vache Borgou. De 1967 à 1989, 91 âges au premier vêlage et 524 intervalles entre vêlages ont été utilisés. L’âge moyen au premier vêlage a été de 1 122 ± 257 jours (37,4 ± 7,9 mois, soit 3 ans et 26 jours) et l’intervalle moyen entre vêlages a été de 450 ± 132 jours (14,8 ± 4,4 mois, soit un an et 2,8 mois). L’effet de l’âge au premier vêlage sur l’intervalle entre vêlages a été très significatif (p < 0,001) et faible (r = 0,22). [less ▲]

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See detailSynthesis of peptide-modified pyoverdins by a fluorescent Pseudomonas strain grown in isoleucine-supplemented medium
Ongena, MARC ULg; Jacques, Philippe ULg; De Pauw, Edwin ULg et al

in Letters in Peptide Science (2002), 8(1), 21-27

The pattern of pyoverdin-type siderophores produced by Pseudomonas putida BTP16 in iron-limited succinate medium supplemented or not with isoleucine was characterized by electrospray ionization mass ... [more ▼]

The pattern of pyoverdin-type siderophores produced by Pseudomonas putida BTP16 in iron-limited succinate medium supplemented or not with isoleucine was characterized by electrospray ionization mass spectrometry. Two new compounds were observed in culture supernatants from BTP16 grown in the presence of isoleucine. For both molecules, mass differences with pyoverdins originally synthesized by the strain were only interpreted considering the incorporation of Ile into the peptide chain. Further evidence supporting this phenomenon was provided by radioactivity incorporation in pyoverdins produced in the presence of C-14-labeled Ile. Our results are discussed in relation to the non-ribosomal mechanism supposed to be involved in the synthesis of these molecules. [less ▲]

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See detailRemarques sur le vocabulaire grec de la traduction
Rochette, Bruno ULg

in Revue Belge de Philologie et d'Histoire (2002), 80

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See detailLe cas clinique du mois. Hepatite cholestatique apres administration de piperacilline.
Dietze, M. A.; Martin, Pierre ULg; Schaaf-Lafontaine, Nicole ULg

in Revue Médicale de Liège (2002), 57(9), 571-4

We describe a patient suffering from infection of the upper respiratory tract, who was treated with a dose of 4 x 4 g of piperacillin over 10 days. Two days after the end of the treatment, she developed ... [more ▼]

We describe a patient suffering from infection of the upper respiratory tract, who was treated with a dose of 4 x 4 g of piperacillin over 10 days. Two days after the end of the treatment, she developed jaundice and had elevated alkaline phosphatase, gammaglutamyltransferase and transaminases. After exclusion of viral hepatitis, a vascular problem, and gall stone disease, the possibility of piperacillin-induced hepatitis was discussed. Lymphocyte transformation test for piperacillin was positive, suggesting an immunological mechanism for the observed hepatopathy. The patient was discharged a few days after in good clinical condition and with reduced liver values. Cholestasis gradually decreased but was detectable for several weeks. The patient had a full clinical and biochemical recovery after 2 months. We conclude that short-term therapy with piperacillin can lead to the same type of hepatopathy as described for amoxycillin/clavulanic acid or antistaphylococcal penicillins. Positive lymphocyte transformation is compatible with an immunological mechanism. [less ▲]

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See detailLe contrat de travail et la signature électronique
Kefer, Fabienne ULg; Barth, H.

in Orientations : la Revue du Droit Social et de la Gestion du Personnel (2002)

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See detailL'organisation au regard de l'esthétique
Servais, Christine ULg; Heller, Thomas

in Recherches en Communication (2002), 17

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See detailDe Mably à Marin. Dans le dédale ornemental de l'imprimeur parisien Quillau (XVIIIe siècle)
Droixhe, Daniel ULg

in Livre et l'Estampe (Le) (2002), 48(158), 43-69

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See detailOn the representation of real numbers using regular languages
Lecomte, Pierre ULg; Rigo, Michel ULg

in Theory of Computing Systems (2002), 35(1, JAN-FEB), 13-38

Using a lexicographically ordered regular language, we show how to represent an interval of R. We determine exactly the possible representations of any element in this interval and study the function ... [more ▼]

Using a lexicographically ordered regular language, we show how to represent an interval of R. We determine exactly the possible representations of any element in this interval and study the function which maps a representation onto its numerical value. We make explicit the relationship between the convergence of finite words to an infinite word and the convergence of the corresponding approximations to a real number. [less ▲]

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See detailThe effect of pH on the alternative oxidase activity in isolated Acanthamoeba castellanii mitochondria.
Jarmuszkiewicz, W.; Hryniewiecka, L.; Sluse, Francis ULg

in Journal of Bioenergetics & Biomembranes (2002), 34(3), 221-226

Mitochondria of Acanthamoeba castellanii possess a cyanide-resistant GMP-stimulated ubiquinol alternative oxidase in addition to the cytochrome pathway. In a previous work it has been observed that an ... [more ▼]

Mitochondria of Acanthamoeba castellanii possess a cyanide-resistant GMP-stimulated ubiquinol alternative oxidase in addition to the cytochrome pathway. In a previous work it has been observed that an interaction between the two ubiquinol-oxidizing pathways exists in intact A. castellanii mitochondria and that this interaction may be due to a high sensitivity of the alternative oxidase to matrix pH. In this study we have shown that the alternative oxidase activity reveals a pH-dependence with a pH optimum at 6.8 whatever the reducing substrate may be. The GMP stimulation of alternative oxidase is also strongly dependent on pH implicating probably protonation/deprotonation processes at the level of ligand and protein with an optimum pH at 6.8. The ubiquinone redox state-dependence of alternative oxidase activity is modified by pH in such a way that the highest activity for a given ubiquinone redox state is observed at pH 6.8. Thus pH, binding of GMP, and redox state of ubiquinone collaborate to set the activity of the GMP-stimulated alternative oxidase in isolated A. castellanii mitochondria. The high pH sensitivity of the alternative oxidase could link inactivation of the cytochrome pathway proton pumps to activation of the alternative oxidase with acceleration of redox free energy dissipation as a consequence. [less ▲]

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See detailLe roman poétique en 1929. Nord, entre fantastique réel et réalisme magique
Denis, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2002), (21), 31-40

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See detailLe miracle 'flamand' n'est pas prêt-à-porter…
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 9-10

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See detailMechanisms of cell death in the injured auditory system: Otoprotective strategies
Lefèbvre, Philippe ULg; Malgrange, Brigitte ULg; Lallemend, François et al

in Audiology & Neuro-otology (2002), 7(3, May-Jun), 165-170

Oxidative stress insults such as neurotrophin withdrawal, sound trauma, hypoxia/ischemia, ototoxic antibiotics, and chemotherapeutic agents have been shown to induce apoptosis of both auditory hair cells ... [more ▼]

Oxidative stress insults such as neurotrophin withdrawal, sound trauma, hypoxia/ischemia, ototoxic antibiotics, and chemotherapeutic agents have been shown to induce apoptosis of both auditory hair cells and neurons. In this paper, we review some components of the apoptotic pathways leading to the death of hair cells and auditory induced by growth factor withdrawal or cisplatin intoxication: (1) reactive oxygen species and free radicals are formed as by-products of several metabolic pathways and these molecules can themselves cause cell damage by reacting with cellular proteins; (2) activation of caspases, and (3) activation of calpain. These mechanisms have several different points at which inhibitors could be targeted to protect cells from programmed cell death, including the prevention of oxidative stress-induced apoptosis and the activation of caspases and calpains. Copyright (C) 2002 S. Karger AG, Basel. [less ▲]

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See detailUpregulation of matrix metalloproteinase-9 in murine 5T33 multiple myeloma cells by interaction with bone marrow endothelial cells
Van Valckenborgh, E.; Bakkus, M.; Munaut, Carine ULg et al

in International Journal of Cancer = Journal International du Cancer (2002), 101

MM is a B-cell malignancy mainly characterized by monoclonal expansion of plasma cells in the BM, presence of paraprotein in serum and occurrence of osteolytic bone lesions. MMPs are a family of ... [more ▼]

MM is a B-cell malignancy mainly characterized by monoclonal expansion of plasma cells in the BM, presence of paraprotein in serum and occurrence of osteolytic bone lesions. MMPs are a family of proteolytic enzymes that can contribute to cancer growth, invasion, angiogenesis, bone degradation and other processes important in the pathogenesis of MM. We investigated MMP-9 production in the 5T33MM murine model. Expression of MMP-9 protein in supernatant and cell extracts was analyzed by gelatin zymography. The in vitro, stroma-independent variant 5T33MMvt showed no protein expression of MMP-9 in contrast to in vivo growing MM cells, 5T33MMvv. However, when 5T33MMvt cells were injected into naive mice and isolated after tumor take (5T33MMvt-vv), they secreted a significant amount of MMP-9. These results were confirmed by specific staining of cytospins with an anti-MMP-9 antibody. The MMP-9 production by 5T33MMvt-vv cells disappeared when the cells were recultured in vitro. These data demonstrated that upregulation of MMP-9 occurs in vivo and that this process is dependent on the microenvironment. Cocultures of 5T33MMvt cells with STR10 BMECs induced MMP-9 in MM cells, as determined by both gelatin zymography and flow-cytometric analysis. In conclusion, our results demonstrate that MMP-9 production by MM cells is upregulated in vivo by the interaction of MM cells with BMECs. [less ▲]

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See detailHormonal measurements in late pregnancy and parturition in dairy cows - possible tools to monitor foetal well being
Kornmatitsuk, B.; Veronesi, M. C.; Madej, A. et al

in Animal Reproduction Science (2002), 72(3-4), 153-164

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The ... [more ▼]

Three dairy heifers (A, B and C) were induced to parturition with two prostaglandin (PG) F-2alpha injections on day 268 and 269 of pregnancy. Signs of approaching parturition were carefully observed. The following parameters were registered: degrees of calving difficulty, date and time of parturition, calf's birth weight and calf's sex. Body temperature was measured and blood samples were taken every 3 h 3 days before the first PGF(2alpha) injection until 3 days after parturition. The plasma concentrations of the PGF2a metabolite, progesterone, cortisol, oestrone sulphate and pregnancy associated glycoproteins (PAGs) were analysed. Heifers A, B and C delivered 48, 51 and 57 h after the first PGF(2alpha) injection, respectively. Heifer A delivered without any signs of calving difficulty, whereas, the parturition was considered to be slight and moderate difficulty occurred in the delivery of heifers B and C, respectively. The calf of heifer C, without any abnormal gross-evidences, was stillborn. All animals had retained foetal membranes. A slight increase of the PGF(2alpha) metabolite at the time of parturition was found only in heifer C, whereas the levels dramatically increased in all animals 15-24 h after parturition. At the same time, progesterone levels decreased within 3 h after the first PGF(2alpha) injection (P < 0.05) and reached 0.8, 2.7 and 12.4 nmol/l at the time of parturition in heifers A, B and C, respectively. High release of cortisol at the time of parturition was seen in heifer C. Rising levels of oestrone sulphate around the time of parturition were recorded in all heifers, whereas, increasing levels of PAGs were recorded only in heifer A. In conclusion, the patterns of the PGF(2alpha) metabolite, cortisol, progesterone and PAGs were changed in the cases of calving difficulty and stillbirth after PGF(2alpha)-induction of parturition. However, the relationship between oestrone sulphate and PAGs and the status of foetal well being prior to parturition require further elucidation. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲]

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See detailComment etablir le bilan de fin de traitement des patients atteints de lymphomes non-hodgkiniens (LNH) de malignite intermediaire ou elevee?
Warland, V.; Jerusalem, Guy ULg; Hustinx, Roland ULg et al

in Revue Médicale de Liège (2002), 57(12), 779-84

Incomplete regression of a lymphomatous mass after chemotherapy and/or radiotherapy constitutes a major problem in the treatment of lymphoma. In patients with persisting tumor, it could be reasonable to ... [more ▼]

Incomplete regression of a lymphomatous mass after chemotherapy and/or radiotherapy constitutes a major problem in the treatment of lymphoma. In patients with persisting tumor, it could be reasonable to use salvage therapy and possibly hematopoietic stem cell transplantation at the time of minimal disease rather than at the time of clinically overt relapse. The authors reviewed the most appropriate imaging techniques for the assessment of response to treatment. The limitations of CT and MRI for predicting the nature of residual masses are well known. 67Ga scintigraphy has become a standard procedure for the posttreatment evaluation of patients with lymphoma, but it appears that 18F-FDG PET may be a more effective method. Personal experience in the field of PET scan is reported. Although PET should be considered the noninvasive imaging modality of choice, a histological confirmation of residual disease is always necessary before starting salvage therapy. 18F-fluorodeoxyglucose is not a tumor specific radiotracer. [less ▲]

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See detailNitrosomonas europaea-like bacteria detected as the dominant beta-subclass Proteobacteria ammonia oxidisers in reference and limed acid forest soils
Carnol, Monique ULg; Kowalchuk, G. A.; De Boer, W.

in Soil Biology & Biochemistry (2002), 34

Net nitrification in intact soil cores and the community of ammonia-oxidising bacteria were studied in acid Norway spruce (Picea abies (L.) Karst) and sessile oak (Quercus petraea (Matt. Lieb.)) soils ... [more ▼]

Net nitrification in intact soil cores and the community of ammonia-oxidising bacteria were studied in acid Norway spruce (Picea abies (L.) Karst) and sessile oak (Quercus petraea (Matt. Lieb.)) soils (Haute Ardenne, east Belgium) 18 months after treatment with 5 t ha(-1) dolomite lime. Liming caused a significant increase in nitrification in the upper soil layers (0.15 m) of both stands. DGGE (denaturing gradient gel electrophoresis) profiling after P-subclass ammonia oxidiser-specific polymerase chain reaction (PCR), combined with hybridisation and sequencing of excised DGGE bands revealed a dominance of Nitrosomonas europaea-like sequences, independent of soil horizon, tree species and lime treatment. A minority Nitrosospira-like population was detected, which showed affinity to nitrosospiras previously detected in acid soil. These results contrast with several reports suggesting a dominance of Nitrosospira-like organisms among ammonia oxidiser communities in acid soils. (C) 2002 Elsevier Science Ltd. All rights reserved. [less ▲]

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See detailModellierung von Faserbett-Koaleszenzabscheidern
Speth, H; Pfennig, Andreas ULg; Chatterjee, M et al

in Chemie Ingenieur Technik (2002), 74(3), 266-270

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See detailTransient aurora on Jupiter from injections of magnetospheric electrons
Mauk, B. H.; Clarke, J. T.; Grodent, Denis ULg et al

in Nature (2002), 415(6875), 1003-1005

Energetic electrons and ions that are trapped in Earth's magnetosphere can suddenly be accelerated towards the planet(1-5). Some dynamic features of Earth's aurora (the northern and southern lights) are ... [more ▼]

Energetic electrons and ions that are trapped in Earth's magnetosphere can suddenly be accelerated towards the planet(1-5). Some dynamic features of Earth's aurora (the northern and southern lights) are created by the fraction of these injected particles that travels along magnetic field lines and hits the upper atmosphere(4). Jupiter's aurora appears similar to Earth's in some respects; both appear as large ovals circling the poles and both show transient events(6-11). But the magnetospheres of Jupiter and Earth are so different-particularly in the way they are powered-that it is not known whether the magnetospheric drivers(12) of Earth's aurora also cause them on Jupiter. Here we show a direct relationship between Earth-like injections of electrons in Jupiter's magnetosphere and a transient auroral feature in Jupiter's polar region. This relationship is remarkably similar to what happens at Earth, and therefore suggests that despite the large differences between planetary magnetospheres, some processes that generate aurorae are the same throughout the Solar System. [less ▲]

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See detailRéduire la taille des classes dans l'enseignement fondamental : pour des discriminations vraiment positives...
Lafontaine, Dominique ULg

in Cahiers du Service de Pédagogie Expérimentale (SPE) (2002), 11-12

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See detailUne étude inédite de Franz Cumont sur le vocabulaire des inscriptions funéraires chrétiennes de Gaule
Rochette, Bruno ULg

in Bulletin de l'Institut Historique Belge de Rome (2002), 72

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See detailCaractérisation physico-chimique de gommes végétales exsudées par quelques acacias du Burkina Faso
Djiré, O.; Ntema, P.; Zgoulli, S. et al

in Science et Technique (2002), 25(2), 37-47

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See detailImpact des méthodes d'application sur l'efficacité d'un traitement à base de Pichia anomala souche K contre les maladies de post-récolte des pommes
Jijakli, Haissam ULg; Dickburt, Catherine; Lepoivre, Philippe ULg et al

in VIII journées scientifiquesBiotechnologies végétales: valorisation pour une agriculture durable (2002)

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See detailObservational survey of NSAID-related upper gastro-intestinal adverse events in Belgium
Belaiche, Jacques ULg; Burette, A.; De Vos, M. et al

in Acta Gastro-Enterologica Belgica (2002), 65(2, Apr-Jun), 65-73

Objectives : To evaluate the impact of NSAID use on current routine upper GI endoscopy (UGIE) and to compare the lesions found in NSAID users and non-users. Methods : Participating gastroenterologists ... [more ▼]

Objectives : To evaluate the impact of NSAID use on current routine upper GI endoscopy (UGIE) and to compare the lesions found in NSAID users and non-users. Methods : Participating gastroenterologists; consecutively documented outpatients with and without suspicion of bleeding, referred for upper gastrointestinal endoscopy. Patient characteristics, presence of risk factors, NSAID use and endoscopic findings were reported on standard data collection forms. Main results : A total of 2685 non-bleeding and 159 bleeding patients were enrolled within a time period of 2 months. NSAID therapy was present in 20% of the non-bleeding patients and at least 9% of referrals for endoscopy were directly related to suspected NSAID adverse events. Nearly half of acute bleeding patients (42%) were NSAID users, including aspirin for cardioprevention. Warning digestive symptoms prior to acute bleeding were frequently absent (56%). Oesophagitis was the main endoscopic diagnosis (51% of patients). Gastroduodenal (GD) ulcer was significantly more frequent in NSAID users, whereas oesophagitis and bleeding oesophageal varices were more frequent among non-users. Analysis of odds ratio's demonstrated NSAID use to significantly increase the risk for gastric ulcer in the whole patient group (OR = 2.73; 95% confidence interval (CI) : 1.983.77; p < 0.001) and, in addition, for duodenal ulcer in the elderly (>65y) subgroup (OR = 2.91; 95 % CI : 1.52-5.59; p < 0.05). Conclusions : This survey confirms the high incidence of GD ulcers in NSAID users and the risk for serious gastrointestinal complications, often occurring without warning symptoms. It underlines the impact of NSAID use on the routine endoscopy load, the necessity of careful selection of patients for NSAID prescriptions and the need for gastropreventive measures, particularly in elderly patients and patients associating multiple risk factors. [less ▲]

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See detailIntravascular malignant lymphomatosis: report of 2 neurological cases
Vandenheede, Michel; Dioh, Alioune ULg; Maertens De Noordhout, Alain ULg et al

in Acta Neurologica Belgica (2002), 102(2), 76-81

We report two cases of intravascular malignant lymphomatosis (IML) with a clinical expression limited to the central nervous system. The first patient presented with signs of cerebral, cerebellar and ... [more ▼]

We report two cases of intravascular malignant lymphomatosis (IML) with a clinical expression limited to the central nervous system. The first patient presented with signs of cerebral, cerebellar and spinal cord involvement. The second had an isolated involvement of the spinal cord. In both cases the diagnosis was made at post-mortem examination; pre-mortem examination of biopsy tissue from peripheral nerve and muscle in the first case, spleen and liver in the second were unhelpful for the diagnosis of lymphoma. We review the published literature on IML, its ante-mortem diagnosis and treatment. [less ▲]

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See detailExamen critique de l'étymologie de brasser
Boutier, Marie-Guy ULg

in Dialectes de Wallonie (2002), 29-30

La filiation traditionnellement établie entre gaulois brace "matière servant à préparer la bière" (dont provient fr. brais) et fr. brasser "préparer la bière" est réexaminée dans cet article par l'examen ... [more ▼]

La filiation traditionnellement établie entre gaulois brace "matière servant à préparer la bière" (dont provient fr. brais) et fr. brasser "préparer la bière" est réexaminée dans cet article par l'examen de l'ensemble du vocabulaire technologique wallon de la brasserie et des réalités concrètes qui sont désignées: la préparation du brais, d'une part; le brassage de la bière, d'autre part. [less ▲]

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See detailDetermination of a coalescence parameter from batch-settling experiments
Henschke, M; Schlieper, L; Pfennig, Andreas ULg

in Chemical Engineering Journal (2002), 85((2-3)), 369-378

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See detailPolyester layered silicate nanohybrids by controlled grafting polymerization
Lepoittevin, Bénédicte; Pantoustier, Nadège; Alexandre, Michaël ULg et al

in Journal of Materials Chemistry (2002), 12(12), 3528-3535

Poly( epsilon-caprolactone) (PCL) layered silicate nanohybrids were synthesized by ring opening polymerization of epsilon-caprolactone according to a well-controlled coordination-insertion mechanism ... [more ▼]

Poly( epsilon-caprolactone) (PCL) layered silicate nanohybrids were synthesized by ring opening polymerization of epsilon-caprolactone according to a well-controlled coordination-insertion mechanism. Montmorillonites were surface-modified by non functional (trimethylhexadecylammonium) and hydroxy functional alkylammonium cations, i.e., (2-hydroxyethyl) dimethylhexadecylammonium. The hydroxy functions available at the clay surface were activated into tin( II or IV) or Al(III) alkoxide initiators for lactone polymerization, thus yielding surface-grafted PCL chains. The surface-grafted PCL chains were recovered by an ionic exchange reaction with lithium chloride and they were analyzed by size exclusion chromatography. The PCL molar mass was measured as a function of the hydroxy content of the clay that was modulated by exchanging the Na cations with mixtures of non-functional and hydroxy functional ammonium cations of different compositions. Nanohybrids were also characterized by small-angle X-ray diffraction, transmission electron microscopy and thermogravimetry. The PCL molar mass and the nanocomposite morphology (i.e., exfoliation and/or intercalation) were readily tuned by the content of the hydroxy groups available at the clay surface. Surface-grafted aluminium trialkoxide species proved highly efficient in initiating polymerization that leads to PCL chains of controlled molar mass and narrow molecular weight distribution with polydispersity indices as low as 1.2. [less ▲]

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See detailMechanisms controlling the oxygen consumption in experimentally induced hypochloremic alkalosis in calves
Cambier, Carole ULg; Clerbaux, Thierry; Amory, Hélène ULg et al

in Veterinary Research (2002), 33

The study was carried out on healthy Friesian calves (n = 10) aged between 10 and 30 days. Hypochloremia and alkalosis were induced by intravenous administration of furosemide and isotonic sodium ... [more ▼]

The study was carried out on healthy Friesian calves (n = 10) aged between 10 and 30 days. Hypochloremia and alkalosis were induced by intravenous administration of furosemide and isotonic sodium bicarbonate. The venous and arterial blood samples were collected repeatedly. 2,3-diphosphoglycerate (2,3-DPG), hemoglobin and plasmatic chloride concentrations were determined. The red blood cell chloride concentration was also calculated. pH, PCO2 and PO2 were measured in arterial and mixed venous blood. The oxygen equilibrium curve (OEC) was measured in standard conditions. The correspondence of the OEC to the arterial and mixed venous compartments was calculated, taking blood temperature, pH and PCO2 values into account. The oxygen exchange fraction (OEF%), corresponding to the degree of blood desaturation between the arterial and mixed venous compartments and the amount of oxygen released at the tissue level by 100 mL of blood (OEF Vol%) were calculated from the arterial and mixed venous OEC, combined with PO2 and hemoglobin concentration. Oxygen delivery (DO2) was calculated using the arterial oxygen content, the cardiac output measured by thermodilution, and the body weight of the animal. The oxygen consumption (VO2) was derived from the cardiac output, OEF Vol% and body weight values. Despite the plasma hypochloremia, the erythrocyte chloride concentration was not influenced by furosemide and sodium bicarbonate infusion. Due to the alkalosis-induced increase in the 2,3-DPG, the standard OEC was shifted to the right, allowing oxygen to dissociate from hemoglobin more rapidly. These changes opposed the increased affinity of hemoglobin for oxygen induced by alkalosis. Moreover, respiratory acidosis, hemoconcentration, and the slight decrease in the partial oxygen pressure in mixed venous blood (Pvo(2)) tended to improve the OEF Vol% and maintain the oxygen consumption in a physiological range while the cardiac output, and the oxygen delivery were significantly decreased. It may be concluded that, despite reduced oxygen delivery, oxygen consumption is maintained during experimentally induced hypochloremic alkalosis in healthy 10-30 day old calves [less ▲]

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See detailEnzymatically prepared n-alkyl esters of glucuronic acid: The effect of hydrophobic chain length on surface properties
Blecker, Christophe ULg; Piccicuto, S.; Lognay, Georges ULg et al

in Journal of Colloid & Interface Science (2002), 247(2), 424-428

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and ... [more ▼]

The effect of hydrophobic chain length on surface properties of enzymatically prepared n-alkyl esters of glucuronic acid are examined. Dynamic parameters from Hua and Rosen's mathematical model and equilibrium surface tension are presented for esters with octyl, decyl, dodecyl, and tetradecyl alkyl segments. Increasing the alkyl chain length has a significant influence on the surface activity. Decyl and dodecyl glucuronate exhibit an interesting adsorption speed associated with foaming capacity. Octyl glucuronate exhibits a micellar organization as its bulk concentration is over 10.68 mM. (C) 2002 Elsevier Science (USA). [less ▲]

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See detailPerformance de Acacia Auriculiformis (Cunn. A.) dans le système agroforestier au Sud-Bénin
Fonton, H. N.; Claustriaux, Jean-Jacques ULg; Agbahungba, G.

in Annales des Sciences Agronomiques du Bénin (2002), 3(1), 65-79

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See detailInfluence de l'hérédité, du sexe et de la saison sur le type d'épisode dans le trouble bipolaire.
Mortazi, M.; Bertrand, Jean-Marie ULg; Triffaux, Jean-Marc ULg et al

in Revue Médicale de Liège (2002), 57(3), 171-5

The aim of this work was to investigate if sex, age, family history, season and hypothyroidism have any influence on the type of episodes (manic, depressive, mixed) seen in bipolar patients. This ... [more ▼]

The aim of this work was to investigate if sex, age, family history, season and hypothyroidism have any influence on the type of episodes (manic, depressive, mixed) seen in bipolar patients. This retrospective study concerns a sample of 208 patients with a diagnosis of bipolar disorder (type I or II), who were admitted in one of two psychiatric centers between July 1996 and June 2000. The sex-ratio was 2.8 females for 1 male. Sex, family history and hypothyroidism were not associated with any type of episode. A higher percentage of depressive episodes was observed in the patients who were older than 50 and the average age of depressive patients was higher than that of other patients. There was no seasonal pattern in this study and the season did not influence the type of episode. The results indicate no influence of sex, season, family history and hypothyroidism on the type of episode presented. On the opposite, age seems to favour depression episode. [less ▲]

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See detailDu Fantastique réel au réalisme magique
Denis, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2002), (21),

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See detailBriefe an Goethe. Gesamtausgabe in Regestform. Bd. 6.1 und 6.2 (Rezension)
Viehöver, Vera ULg

in Germanistik (2002), 43(3/4), 5288

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See detailAdsorption of selenium wires in silicalite-1 zeolite: a first order transition in a microporous system
Bichara, C.; Raty, Jean-Yves ULg; Pellenq, RJ-M

in Physical Review Letters (2002), 89(1), 016101-1-016101-016101-4016101-016101-4

A tight binding grand canonical Monte Carlo simulation of the adsorption of selenium in silicalite-1 zeolite is presented. The calculated adsorption-desorption isotherms exhibit characteristic features of ... [more ▼]

A tight binding grand canonical Monte Carlo simulation of the adsorption of selenium in silicalite-1 zeolite is presented. The calculated adsorption-desorption isotherms exhibit characteristic features of a first order transition, unexpected for adsorption in a microporous system with pore size of the order of 0.5 to 0.6 nm. We analyze this behavior as a result of the favored twofold coordinated chain structure of selenium that grows inside the complex three-dimensional microchannel network of silicalite. This analysis is confirmed by simpler calculations of a lattice gas-type model [less ▲]

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See detailGlobal democratic consensus on neuropathological disease criteria.
Achim, Cristian; Auer, Roland; Bergeron, Catherine et al

in Lancet Neurology (2002), 1(6), 340

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See detailGestion de l’information dans les pratiques de soins intégrés
Prevost, Marianne; Della Giustina, Vanni; Gosselain, Yves et al

in Santé Conjuguée (2002), 19

Gestion de l’information dans les pratiques de soins intégrés, autrement dit, GIPSI : tel était le thème d’un forum organisé le 15 décembre 2001 à Natoye par la Fédération des maisons médicales, lequel a ... [more ▼]

Gestion de l’information dans les pratiques de soins intégrés, autrement dit, GIPSI : tel était le thème d’un forum organisé le 15 décembre 2001 à Natoye par la Fédération des maisons médicales, lequel a rassemblé une bonne soixantaine de participants issus de trente et une maisons médicales. L’information, c’est un élément clé pour tous les soignants, toutes les équipes : les pratiques de soins reposent sur, et génèrent, une foule d’informations de tous ordres, qu’il n’est pas toujours aisé de rassembler, de trier, d’exploiter à bon escient… comment organiser le recueil et l’analyse de toutes les informations utiles pour améliorer le bien-être des patients – et des soignants ? Quels systèmes d’information peuvent-ils faire gagner du temps, s’intégrer de manière souple dans le travail quotidien, sans poser trop de difficultés nouvelles ? Comment mieux communiquer entre soignants, entre soignants et patients ? Clarifier les questions relatives au partage de l’information, la transmission, la confidentialité ? [less ▲]

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See detailWilliam S. Burroughs: Du cut-up au simulacre
Claisse, Frédéric ULg

in Réseaux : Revue Interdisciplinaire de Philosophie Morale et Politique (2002), (94-95-96), 151-174

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See detailPistes de réflexion pour développer, à l’école, les compétences de tous les élèves
Beckers, Jacqueline ULg

in L’École valdôtaine (2002), 55

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See detailA multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis.
Pierard, Claudine ULg; Goffin, Véronique ULg; Decroix, Jacques et al

in Skin Pharmacology & Applied Skin Physiology (2002), 15(6), 434-41

Ketoconazole (KET) and zinc pyrithione (ZPT) are compounds active against the Malassezia spp. yeasts, which are believed to play a major role in dandruff and seborrheic dermatitis. We compared the ... [more ▼]

Ketoconazole (KET) and zinc pyrithione (ZPT) are compounds active against the Malassezia spp. yeasts, which are believed to play a major role in dandruff and seborrheic dermatitis. We compared the efficacy and safety of KET 2% and ZPT 1% in shampoo formulations for the alleviation of severe dandruff and seborrheic dermatitis. This open randomized, parallel-group trial began with a 2-week run-in phase during which subjects applied a neutral non-antidandruff shampoo. It was followed by a 4-week randomized treatment phase and a subsequent 4-week follow-up phase without treatment. Shampooing during the treatment period was carried out twice weekly for the KET group and at least twice weekly for the ZPT group in accordance with the label instructions. A total of 343 subjects were recruited to enter the trial. Of the 331 eligible volunteers, 171 were randomized to KET 2% and 160 to ZPT 1%. Clinical assessments were performed. Beneficial effects were evidenced for both medicated shampoos, but the effect was significantly better for KET 2%, which achieved a 73% improvement in the total dandruff severity score compared with 67% for ZPT 1% at week 4 (p < 0.02). The recurrence rate of the disease was also significantly lower following KET 2% treatment than following ZPT 1% treatment. As a consequence, the overall clearing of the skin condition at the end of treatment and follow-up phase was in favor of the KET 2% formulation (p = 0.004). Side effects were minimal. It is concluded that after a 4-week treatment, KET 2% shampoo was significantly superior to ZPT 1% shampoo in the treatment of subjects with severe dandruff or seborrheic dermatitis of the scalp. It is our assumption that this difference is noticeable for the patient and as a consequence relevant. Both formulations were well tolerated. [less ▲]

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See detailLésion du nerf interosseux postérieur liée à une randonnée prolongée en vélo-tout-terrain (VTT)
Zeevaert, Bernard; CRIELAARD, Jean-Michel ULg; WANG, François-Charles ULg

in Neurophysiologie Clinique = Clinical Neurophysiology (2002)

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See detailPsychologie et histoire : une réflexion à double sens
Richelle, Marc ULg

in Anuario de Psicologia (2002), 33(2), 231-247

This reflection on the relations between psychology and history addresses four distinct issues. The first is the history of psychology: the importance of reference to the past, even if only to put current ... [more ▼]

This reflection on the relations between psychology and history addresses four distinct issues. The first is the history of psychology: the importance of reference to the past, even if only to put current research and theory into perspective. Second, the essential historical dimension of human is presented as a crucial aspect in defining the very object of psychological science; the "historical psychology" approach, specifically its French variety as represented by Ignace Meyerson's legacy, is breifly discussed. Third, the contribution of psychology to the work of historians is considered. Finally, the joint involvement of both psychology and history in contemporary society is discussed with reference to the use (and abuse) of history in the construction of collective identity and to the claims for repair for offenses and damages made in the past, echoed by the declarations of guilt on the part of their perpetrators, on more exactly their descendants. These issues are discussed in the light of psychological approaches to memory and forgetting. [less ▲]

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See detailPrélèvement de l’isthme encéphalique pour la recherche de l’encéphalopathie spongiforme transmissible chez le mouton
Gabriel, Annick ULg; Jacobs, Christine ULg; Simoens, P.

in Annales de Médecine Vétérinaire (2002), 146(5), 295-300

Depuis le premier avril 2002, une directive de l'Union Européenne contraint la Belgique à tester les chèvres et les moutons, en plus des bovins, dans le cadre de la recherche d'encéphalopathie spongiforme ... [more ▼]

Depuis le premier avril 2002, une directive de l'Union Européenne contraint la Belgique à tester les chèvres et les moutons, en plus des bovins, dans le cadre de la recherche d'encéphalopathie spongiforme transmissible. Comme chez les bovins, le diagnostic est réalisé à partir d'un prélèvement de l'isthme encéphalique au niveau de l'obex. Des différences morphologiques entre l'isthme encéphalique des moutons et chèvres et celui des bovins ont nécessité quelques ajustements de la méthode de prélèvement. Dans cette étude, les particularités techniques du prélèvement et certaines caractéristiques morphologiques du cerveau ovin sont décrites. Les différences majeures, par rapport aux bovins, sont d'une part les dimensions plus petites, et d'autre part le rétrécissement caudal très marqué de l'isthme encéphalique. [less ▲]

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