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See detailUse of Tyrosine Kinase Inhibitors to Prevent Relapse After Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Position Statement of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Giebel, S.; Czyz, A.; Ottmann, O. et al

in Cancer (in press)

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a standard of care for patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL). The introduction of tyrosine ... [more ▼]

Allogeneic hematopoietic stem cell transplantation (alloHSCT) is a standard of care for patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL). The introduction of tyrosine kinase inhibitors (TKIs) to first-line therapy has improved overall outcomes; however, a significant proportion of patients still relapse after alloHSCT. Posttransplant TKI maintenance was demonstrated to reduce the risk of relapse in a large retrospective study and, therefore, should be considered a valuable option. This consensus paper, written on behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation, presents an overview of clinical studies on the use of TKIs after alloHSCT and proposes practical recommendations regarding the choice of TKI, treatment timing, and dosage. It is hoped that these recommendations will become the state of art in this field and, more importantly, lead to a reduction of Ph-positive ALL relapse after alloHSCT. [less ▲]

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See detailRONALD JENN ET CORINE OSTER (dir.) (2014) : Territoires de la traduction. Artois : Artois Presses Université, 212 p.
Oumarou Mal Mazou, Rachid ULg

in Meta : Journal des Traducteurs = Meta : Translators' Journal (in press)

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See detailErnst Mach, psychologue de la forme ?
Zincq, Aurélien ULg

in Philosophie (in press)

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See detailDistances between nested densities and a measure of the impact of the prior in Bayesian statistics
Ley, Christophe; Reinert, Gesine; Swan, Yvik ULg

in Annals of Applied Probability (in press)

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See detailLes associations des enfants et jeunes travailleurs du Burkina Faso comme espace d’expression de la capacité d’action des enfants ?
Wouango, Joséphine ULg

in Enfances Familles Générations (in press)

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années ... [more ▼]

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années 1980. Le mouvement est fondé sur deux grands principes : les douze droits prioritaires des enfants et jeunes travailleurs et le principe du « protagonisme » (l’enfant travailleur comme acteur capable) . Ce chapitre présente et analyse le fonctionnement de ce mouvement au Burkina Faso, les changements qu’il a contribué à apporter à la question sociale du travail des enfants et les résultats de la mise en application des principes annoncés. S’appuyant sur une enquête ethnographique menée en son sein, le texte offre des données inédites sur les réalités d’un acteur collectif qui, en utilisant à son avantage la rhétorique de la « participation » des enfants (art.12, Convention des droits de l’enfant), a réussi à s’insérer dans l’arène nationale de la protection de l’enfance. Toutefois, la question de la place et du rôle des enfants ainsi que celle du “vieillissement” des membres sont quelques-uns des défis auxquels la section burkinabè du mouvement doit faire face. [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailThe Sense of Taste in Eighteenth-Century France. Flavours of Silence and Words of Perception
Von Hoffmann, Viktoria ULg

in De achttiende eeuw : Documentatieblad van de Werkgroep Achttiende Eeuw (in press)

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See detailDirect prediction of spatially and temporally varying physical properties from time-lapse electrical resistance data
Hermans, Thomas ULg; Oware, Erasmus; Caers, Jef

in Water Resources Research (in press)

Time-lapse applications of electrical methods have grown significantly over the last decade. However, the quantitative interpretation of tomograms in terms of physical properties, such as salinity ... [more ▼]

Time-lapse applications of electrical methods have grown significantly over the last decade. However, the quantitative interpretation of tomograms in terms of physical properties, such as salinity, temperature or saturation, remains difficult. In many applications, geophysical models are transformed into hydrological models, but this transformation suffers from spatially and temporally varying resolution resulting from the regularization used by the deterministic inversion. In this study, we investigate a prediction-focused approach (PFA) to directly estimate subsurface physical properties with electrical resistance data, circumventing the need for classic tomographic inversions. First, we generate a prior set of resistance data and physical property forecast through hydrogeological and geophysical simulations mimicking the field experiment. We reduce the dimension of both the data and the forecast through principal component analysis in order to keep the most informative part of both sets in a reduced dimension space. Then, we apply canonical correlation analysis to explore the relationship between the data and the forecast in their reduced dimension space. If a linear relationship can be established, the posterior distribution of the forecast can be directly sampled using a Gaussian process regression where the field data scores are the conditioning data. In this paper, we demonstrate PFA for various physical property distributions. We also develop a framework to propagate the estimated noise level in the reduced dimension space. We validate the results by a Monte Carlo study on the posterior distribution and demonstrate that PFA yields accurate uncertainty for the cases studied. [less ▲]

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See detailMoisture content determination in an antibody-drug conjugate freeze-dried medicine by near-infrared spectroscopy: a case study for release testing
Clavaud, Matthieu ULg; Roggo, Yves; Dégardin, Klara et al

in Journal of Pharmaceutical & Biomedical Analysis (in press)

The use of Near-infrared spectroscopy (NIRS) as a fast and non-destructive technique was employed for moisture content (MC) determination in Antibody-drug conjugates (ADCs) in replacement to Karl Fischer ... [more ▼]

The use of Near-infrared spectroscopy (NIRS) as a fast and non-destructive technique was employed for moisture content (MC) determination in Antibody-drug conjugates (ADCs) in replacement to Karl Fischer (KF) method. The lab analysis of ADCs, high potent medicines, should be performed in conditions ensuring the operator’s safety and using secured analytical tools like NIRS. A NIRS method was first developed and validated in compliance with current guidelines. The novelty of this work first lies in the large number of samples prepared for a wide moisture calibration range of 0.51% to 4.01%. Then, the classical Partial Least Square (PLS) regression was used as chemometric tool for the computation of the model. Excellent predictive calibration results were shown. A coefficient of correlation (r) value of 0.99 was obtained. An intercept value of 0.02 and a slope of 0.99 were observed, while the root mean square error of calibration (RMSEC) and the root mean square error of prediction (RMSEP) were respectively 0.10% and 0.12%. In addition, instrumentation, model performances and robustness of the method were evaluated, demonstrating the validation results. Calibration transfer issue and impact of the number of samples were also evaluated. Consequently, a validation strategy was introduced as a basis for submission to the health authorities’ for release and stability activities in a cGMP environment in replacement of the KF method. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailResting-state test–retest reliability of a priori defined canonical networks over different preprocessing steps
Varikuti, Deepthi; Hoffstaedter, Felix; Genon, Sarah ULg et al

in Brain Structure & Function (in press)

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI ... [more ▼]

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI, however, is impeded by various nuisance signals that reduce the stability of functional connectivity. Several methods exist to address this predicament, but little consensus has yet been reached on the most appropriate approach. Given the crucial importance of reliability for the development of clinical applications, we here investigated the effect of various confound removal approaches on the test–retest reliability of functional connectivity estimates in two previously defined functional brain networks. Our results showed that gray matter masking improved the reliability of connectivity estimates, whereas denoising based on principal components analysis reduced it. We additionally observed that refraining from using any correction for global signals provided the best test–retest reliability, but failed to reproduce anti-correlations between what have been previously described as antagonistic networks. This suggests that improved reliability can come at the expense of potentially poorer biological validity. Consistent with this, we observed that reliability was proportional to the retained variance, which presumably included structured noise, such as reliable nuisance signals (for instance, noise induced by cardiac processes). We conclude that compromises are necessary between maximizing test–retest reliability and removing variance that may be attributable to non-neuronal sources. [less ▲]

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See detailA Theory of Soft Capture
Agrell, Per; Gautier, Axel ULg

in Scandinavian Journal of Economics (in press)

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to ... [more ▼]

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to provide a signal for the type of a regulated firm. Only the firm can observe his type and the production of a correlated signal with a given accuracy is costly for the regulator. The firm can costlessly provide an alternative signal of lower accuracy that is presented to the regulator. In a self-enforcing equilibrium, the regulator transmits the firm-produced signal, internalizes its own savings in information cost and the firm enjoys higher information rents. The main feature of soft capture is that it is not based on a reciprocity of favors but on a congruence of interests between the firm and the regulator. [less ▲]

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See detailMotiver sans contraindre, séduire sans manipuler
Defays, Jean-Marc ULg

in Le Langage et l'Homme (in press)

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See detailGlioblastoma-derived extracellular vesicles induce tumor-supportive phenotypes in monocytic cells
de Vrij, Jeroen; Maas, Sybren; Kwappenberg, Kitty et al

in International Journal of Cancer = Journal International du Cancer (in press)

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See detailEnabling efficient PET imaging of Synaptic Vesicle glycoprotein 2A (SV2A) with a robust and one-step radiosynthesis of a highly potent 18F-labelled ligand ([18F]UCB-H)
Warnier, Corentin ULg; Lemaire, Christian ULg; Becker, Guillaume ULg et al

in Journal of Medicinal Chemistry (in press)

We herein describe the straightforward synthesis of a stable pyridyl(4- methoxyphenyl)iodonium salt and its [18F]radiolabelling within a one-step, fully automated and cGMP compliant radiosynthesis of [18F ... [more ▼]

We herein describe the straightforward synthesis of a stable pyridyl(4- methoxyphenyl)iodonium salt and its [18F]radiolabelling within a one-step, fully automated and cGMP compliant radiosynthesis of [18F]UCB-H ([18F]7), a PET tracer for the imaging of Synaptic Vesicle glycoprotein 2A (SV2A). Over the course of one year, 50 automated productions provided 34±2% of injectable [18F]7 from up to 285 GBq (7.7 Ci) of [18F]fluoride in 50 minutes (uncorrected radiochemical yield. Specific Activity = 815±185 GBq/μmol). The successful implementation of our synthetic strategy within routine, high-activity and cGMP productions attests to its practicality and reliability for the production of large doses of [18F]7. In addition to enabling efficient and cost-effective clinical research on a range of neurological pathologies through the imaging of SV2A, this work further demonstrates the real value of iodonium salts for the cGMP 18F-PET tracer manufacturing industry, and their ability to fulfill practical and regulatory requirements in that field. [less ▲]

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See detailResurgence of Schmallenberg virus in Belgium after 3 years of epidemiological silence
Delooz, L; Saegerman, Claude ULg; Quinet, C et al

in Transboundary and Emerging Diseases (in press)

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See detailOpen Science: a revolution in sight?
Rentier, Bernard ULg

in Interlending & Document Supply (in press)

• Purpose This article aims at describing the evolution of scientific communication, largely represented by the publication process. It notes the disappearance of the traditional publication on paper and ... [more ▼]

• Purpose This article aims at describing the evolution of scientific communication, largely represented by the publication process. It notes the disappearance of the traditional publication on paper and its progressive replacement by electronic publishing, a new paradigm implying radical changes in the whole mechanism. It aims also at warning the scientific community about the dangers of some new avenues and why, rather than subcontracting an essential part of its work, it must take back a full control of its production. • Design/methodology/approach The article reviews the emerging concepts in scholarly publication and aims to answer frequently asked questions concerning free access to scientific literature as well as to data, science and knowledge in general. • Findings The article provides new observations concerning the level of compliance to institutional open access mandates and the poor relevance of journal prestige for quality evaluation of research and researchers. The results of introducing an open access policy at the University of Liège are noted. • Social implications Open access is, for the first time in human history, an opportunity to provide free access to knowledge universally, regardless of either the wealth or the social status of the potentially interested readers. It is an essential breakthrough for developing countries. • Value Open access and Open Science in general must be considered as common values that should be shared freely. Free access to publicly generated knowledge should be explicitly included in universal human rights. There are still a number of obstacles hampering this goal, mostly the greed of intermediaries who persuade researchers to give their work for free, in exchange for prestige. The worldwide cause of Open Knowledge is thus a major universal issue for the 21st Century. [less ▲]

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See detailHigh spatial resolution of late-Holocene human activities in the moist forests of central Africa using soil charcoal and charred botanical remains
Morin, Julie ULg; Biwolé, Achille; Gorel, Anaïs ULg et al

in Holocene (in press)

Palaeoecological and archaeological studies have demonstrated that human populations have long inhabited the moist forests of central Africa. However, spatial and temporal patterns of human activities ... [more ▼]

Palaeoecological and archaeological studies have demonstrated that human populations have long inhabited the moist forests of central Africa. However, spatial and temporal patterns of human activities have hardly been investigated with satisfactory accuracy. In this study, we propose to characterize past human activities at local scale by using a systematic quantitative and qualitative methodology based on soil charcoal and charred botanical remains. A total of 88 equidistant test-pits were excavated along six transects in two contrasting forest types in southern Cameroon. Charred botanical remains were collected by water-sieving and sorted by type (wood charcoals, oil palm endocarps, and unidentified seeds). A total of 50 Accelerator Mass Spectrometry 14C dates were also obtained. Results showed that charred macroremains were found at multiple places in the forest, suggesting scattered human activities, which were distributed into two main periods (Phase A: 2300-1300 BP – Phase B: 580 BP to the present). Charred botanical remains indicated two types of land use: (i) domestic, with oil palm endocarps most often associated with potsherds (villages) and (ii) agricultural, with charcoal as probable remnant of slash-and-burn cultivation (fields). Oil palm endocarp abundance decreased with distance from the identified human settlements. Our methodology allowed documenting, at high resolution, the spatial and temporal patterns of human activities in central African moist forests and could be applied to other tropical contexts. [less ▲]

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See detailJohn of Trevisa légitimise la traduction en langue anglaise (vers 1387)
Dor, Juliette ULg

in The Medieval Translator. Traduire au Moyen Âge (in press), TMT 16

A l'instar de Chaucer ou des milieux wyclifiens, Trevisa revendique pour le nouveau lectorat/auditorat vernaculaire le droit d'accéder au savoir. Il s'appuie notamment sur la "translatio studii", le ... [more ▼]

A l'instar de Chaucer ou des milieux wyclifiens, Trevisa revendique pour le nouveau lectorat/auditorat vernaculaire le droit d'accéder au savoir. Il s'appuie notamment sur la "translatio studii", le modèle français et l'autorité culturelle qu'avait connue l'anglais avant Hastings. [less ▲]

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See detailIs the sword moss (Bryoxiphium) a preglacial Tertiary relict?
Patino, J.; Goffinet, B.; Sim-Sim, M.A. et al

in Molecular Phylogenetics & Evolution (in press)

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See detailSpecific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice
Scoumanne, Ariane; Molina Ortiz, Patricia ULg; Monteyne, Daniel et al

in Advances in Biological Regulation (in press)

Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is the last identified member of the inositol 1,4,5-trisphosphate 3-kinases family which phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5 ... [more ▼]

Inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) is the last identified member of the inositol 1,4,5-trisphosphate 3-kinases family which phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5-tetrakisphosphate. Although expression and function of the two other family members ITPKA and ITPKB are rather well characterized, similar information is lacking for ITPKC. Here, we first defined the expression of Itpkc mRNA and protein in mouse tissues and cells using in situ hybridization and new antibodies. Surprisingly, we found that cells positive for ITPKC in the studied tissues express either a multicilium (tracheal and bronchial epithelia, brain ependymal cells), microvilli forming a brush border (small and large intestine, and kidney proximal tubule cells) or a flagellum (spermatozoa), suggesting a role for ITPKC either in the development or the function of these specialized cellular structures. Given this surprising expression, we then analyzed ITPKC function in multiciliated tracheal epithelial cells and sperm cells using our Itpkc knock-out mouse model. Unfortunately, no significant difference was observed between control and mutant mice for any of the parameters tested, leaving the exact in vivo function of this third Ins(1,4,5)P3 3-kinase still open. [less ▲]

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See detailSiting Controversies Analysis: Framework and Method for Questioning the Procedure
Rossignol, Nicolas ULg; Parotte, Céline ULg; Joris, Geoffrey ULg et al

in Journal of Risk Research (in press)

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]

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See detailWhom do architects design for in design competitions? A case study
Verhulst, Lore; Elsen, Catherine ULg; Heylighen, Ann

in Journal of Design Research (in press)

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See detailLa question du diagnostic en psychiatrie infanto-juvénile
de Becker, Emmanuel; François, Anne; Kinoo, Philippe et al

in Psychiatrie de l'Enfant (La) (in press)

Dans le vaste champ de l’aide et des soins à l’égard de l’enfant et de l’adolescent, les questions liées au diagnostic transcendent souvent les aspects de prises en charge et de liens thérapeutiques ainsi ... [more ▼]

Dans le vaste champ de l’aide et des soins à l’égard de l’enfant et de l’adolescent, les questions liées au diagnostic transcendent souvent les aspects de prises en charge et de liens thérapeutiques ainsi que les multiples échanges entre professionnels concernés. Le diagnostic pédopsychiatrique est un processus dynamique, modifiable et momentané, les organisations pathologiques étant pour la plupart en transformation permanente. De manière spécifique et en fonction du processus développemental, la thématique du diagnostic en pédopsychiatrie renvoie plus à la question du risque évolutif qu’à la question d’un état pathologique en soi. Les aspects de la continuité des troubles mentaux de l’enfance à l’âge adulte représentent en effet un véritable enjeu développemental. Deux points de vue s’opposent dans la littérature. Le premier, en lien avec un prédéterminisme, estime que les trajectoires sont toutes tracées, l’incertitude reposant dans le diagnostic ; concrètement, il s’agit de repérer de manière précoce des individus à risque parce qu’ils sont porteurs d’un trouble qu’il faut traiter. Le second point de vue considère que les trajectoires ne sont pas déterminées mais sont en réécriture permanente ; ici, le risque ne se situe plus au niveau du diagnostic mais du pronostic, dans un souci de prévention et non de prédiction. L’article propose les réflexions de quatre cliniciens psychiatres infanto-juvéniles sur cette thématique, à la lumière de leur pratique et de leurs échanges. [less ▲]

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See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

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See detailNavigating towards decoupled aquaponic systems: A system dynamics design approach
Goddek, Simon; Espinal, Carlos; Delaide, Boris et al

in Water (in press)

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See detailCutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients
Jurczyszyn, .; Olszewska-Szopa, M.; Hungria, V. et al

in Leukemia & Lymphoma (in press)

Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical ... [more ▼]

Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical outcomes, immunohistochemistry and cytogenetic features, and relevant laboratory data on 53 biopsy-proven skin MM cases. The median time from MM diagnosis to skin involvement was 2 years. There appears to be an overrepresentation of immunoglobulin class A (IgA) and light chain disease in skin MM. We found no correlation between CD56 negative MM and skin infiltration. We found that skin MM patients presented in all MM stages (i.e. ISS stages I to III), and there was no preferential cytogenetic abnormality. Patients with skin MM carry a very poor prognosis with a median overall survival (OS) of 8.5 months as time from skin involvement. Moreover, patients with IgA disease and plasmablastic morphology appear to have a worse OS. [less ▲]

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See detailDPSC colonization of functionalized 3D textiles
Ortiz, Marine; Rosales-Ibáñez, R; Pozos-Guillén, A. et al

in Journal of Biomedical Materials Research, Part B : Applied Biomaterials (in press)

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See detailIncreased diversification rates correlate with bisexuality in liverworts
Laenen, B.; Machac, A.; Gradstein, S.R. et al

in New Phytologist (in press)

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See detailPrudence et ruse comme capacités d’action managériale et politique. Le cas des équipes de direction pénitentiaire belges
Dubois, Christophe ULg

in Sociologie (in press), 7(4), 377-392

This paper aims at analysing the work of prison management teams. Working in organizations that are mainly "auto-regulated" by prison guards, governors’ teams have to cope, for the last fifteen years ... [more ▼]

This paper aims at analysing the work of prison management teams. Working in organizations that are mainly "auto-regulated" by prison guards, governors’ teams have to cope, for the last fifteen years, with a heightened control exercised by the central administration. This “regulation of control” (Reynaud, 1988) is inter alia justified by the endemic phenomenon of overcrowding and the increasing interdependency between prisons and their environment. Despite the constraints implied by these shifts, prison governors preserve some autonomy through two types of deliberative practice allowing them to influence - marginally and ethically – prison organizations and policies. The first one, called practical wisdom or prudence (Champy, 2012), lies in the subtle bypass of the rules in uncertain situations; the second one, called cunning, or ruse (Lécu, 2013), consists in denouncing the hypocrisy of some political discourses with the help of some external partners. [less ▲]

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See detailULTRASONOGRAPHIC FINDINGS IN 13 HORSES WITH LYMPHOMA
Janvier, Valentin; Evrard, Laurence ULg; Cerri, Simona ULg et al

in Veterinary Radiology & Ultrasound (in press)

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See detailDetermination of iohexol and iothalamate in serum and urine by capillary electrophoresis.
Van Houcke, Sofie K.; Seaux, Liesbeth; Cavalier, Etienne ULg et al

in Electrophoresis (in press)

Estimation of glomerular filtration rate (eGFR) is essential to assess kidney function. Iodine containing contrast agents detection by HPLC has been proposed as a safe alternative for inulin or ... [more ▼]

Estimation of glomerular filtration rate (eGFR) is essential to assess kidney function. Iodine containing contrast agents detection by HPLC has been proposed as a safe alternative for inulin or radioactive compounds. However, HPLC is a time-consuming and labour-intensive method. The aim of this study was to develop an assay for iohexol and iothalamate using capillary electrophoresis (CE). Iohexol and iothalamate were directly analysed by CE in serum and urine, using photometric detection (246 nm). Serum peak height was proportional to iohexol and iothalamate concentrations. Detection limits for iohexol and iothalamate were 10 mg/L and 5 mg/L. Limits of quantification were 13.0 mg/L and 15.0 mg/L. Within-run CVs were 4.9% and 6.5%; between-run CVs 3.1-9.9% and 3.8-13.7%. A good correlation was observed between CE and HPLC: y = 1.1703 x + 5.017 (iohexol) and y = 0.7807 x + 11.01 (iothalamate) [y = concentration obtained by CE (mg/L), x = concentration obtained by HPLC (mg/L)]. In addition, CE allowed to determine urinary iohexol concentration. Although the detection limit for CE was higher than for HPLC, CE can still be used for eGFR determination. Advantages of this high throughput method are the absence of sample pretreatment and a minimal sample volume requirement. This article is protected by copyright. All rights reserved. [less ▲]

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See detailNote a Jacopino del Conte e approfondimenti sulla sua attività giovanile
Geremicca, Antonio ULg

in Proporzioni. Annali della Fondazione Roberto Longhi (in press)

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See detailAdvances in diagnosis and management of familial pituitary adenomas
JEDIDI, Haroun ULg; ROSTOMYAN, Lilith; POTORAC, Iulia et al

in International Journal of Endocrine Oncology (in press)

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems ... [more ▼]

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems disorders, 2-3% of the familial pituitary adenomas fit into the familial isolated pituitary adenomas (FIPA) syndrome. 20% of FIPA syndromes have shown mutations in the AIP gene and have distinct clinical characteristics. Recent findings have isolated a new non-AIP FIPA syndrome called X-LAG, resulting from duplication in GPR-101 gene. These new advances in the field of pituitary disease are opening up a new challenging domain to both clinician and researcher. This review will focus on these last findings and their contribution to the diagnosis and the management of familial pituitary adenomas. [less ▲]

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See detailEpistémologie de la théorie du complot
Jamin, Jérôme ULg

in Cahiers de l'Éducation Permanente (Les) (in press)

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See detailBioclimatism in Architecture : an evolutionary perspective
Nguyen, Anh Tuan; Reiter, Sigrid ULg

in International Journal of Design and Nature and Ecodynamics (in press)

Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that ... [more ▼]

Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that the development of bioclimatism in architecture has followed the pattern of a natural evolutionary process in which “natural selection” is likely motivated by several factors, including resources and environment problems, and driven by different mechanisms including novel building design concepts and methods, new standards and codes, discoveries in building science and construction costs. This study is an effort aimed to clarify the evolution process of the bioclimatic approach in architecture over time and its influences on contemporary movements in architecture. The paper shows also that the evolutionary theory generated new scientific tools able to improve building design thanks to simulation-based optimization methods applied to building performances. Finally, this study investigates new motivations in the era of climate change whose effects are expected to introduce more challenges as well as more trends towards a sustainable built environment through the new concept of Eco-adaptive architecture. [less ▲]

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See detailCritique du capitalisme néolibéral et travail rhétorique chez Frédéric Lordon : un discours d’affectation.
Provenzano, François ULg; Janvier, Antoine ULg

in Dissensus (in press)

Les ouvrages de Frédéric Lordon ont offert ces dernières années un éclairage nouveau des mécanismes de la finance et du capitalisme en régime néolibéral, en vertu de la place centrale qu’ils accordent aux ... [more ▼]

Les ouvrages de Frédéric Lordon ont offert ces dernières années un éclairage nouveau des mécanismes de la finance et du capitalisme en régime néolibéral, en vertu de la place centrale qu’ils accordent aux affects. Il est frappant que cette entreprise – qui est triple: analyse de la finance, analyse du capitalisme, analyse de la domination – soit doublée d’une attention portée au discours même qui la développe. On peut repérer une telle attention dans la pluralité des genres de discours qu’investit Frédéric Lordon : ouvrages « savants » ou « universitaires », mais aussi courts essais engagés aux éditions Raisons d’agir, articles de presse dans Le Monde Diplomatique notamment, tenue du blog « La pompe à phynance » sur le site du même journal, et même pièce de théâtre récemment adaptée au cinéma, D’un retournement l’autre. Comédie sérieuse sur la crise financière. En quatre actes, et en alexandrins . Diversité de genre entre les différents types de textes, donc. Diversité interne à chacun de ces textes, aussi : le lecteur de Frédéric Lordon se trouve toujours à cheval sur plusieurs codes rhétoriques dont joue l’auteur dans un même ouvrage. On pourrait bien sûr tenir cette double diversité pour la simple conséquence du talent d’écriture de Lordon, ou d’un plaisir pris par l’auteur à jouer du langage et des ethos qu’il construit. Le présent article propose au contraire de considérer cette diversité comme le résultat d’un véritable travail sur les modalités rhétoriques du discours critique sur le capitalisme financiarisé, qu’il faut articuler aux principaux postulats de sa théorie sociale. L’hypothèse défendue sera, précisément, de considérer qu’il y a une construction rhétorique qui participe de l’entreprise critique et, du même coup, qui s’inscrit comme un geste politique dans une « société des affects ». [less ▲]

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See detailState Created Barriers to Exit - The Example of the Acquisition of Alstom by General Electric
Petit, Nicolas ULg

in Competition Policy International (in press)

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See detailSérialités tintamarresques. Du faux-feuilleton au dictionnaire
Saint-Amand, Denis ULg

in Belphégor : Littérature Populaire et Culture Médiatique (in press)

Parmi les journaux comiques les plus en vue du XIXe siècle, l’hebdomadaire Tintamarre occupe une place de choix. Ses fers de lance, Jean-Louis Commerson et Eugène Vachette s’adjoignent les services ... [more ▼]

Parmi les journaux comiques les plus en vue du XIXe siècle, l’hebdomadaire Tintamarre occupe une place de choix. Ses fers de lance, Jean-Louis Commerson et Eugène Vachette s’adjoignent les services imaginaires de l’écrivain de papier Joseph Citrouillard, qui va rapidement se révéler l’un des contributeurs les plus fidèles du Tintamarre et le sujet de nombreux articles. C’est, dès lors, une double logique sérielle qui se développe autour de Citrouillard, à la fois canular auctorial et antihéros populaire. Cet article interroge les implications et les effets de cette double casquette fantaisiste en ce qui concerne la logique interne du journal et le développement en son sein d’une poétique parodique spécifique, mais également en matière d’institutionnalisation d’une forme de mystification littéraire. [less ▲]

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See detailOccurrence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary, Argentina, and their mid-distance movements along the Northeast Patagonian coast
Failla, Mauricio; Seijas, Veronica; Vermeulen, Els ULg

in Latin American Journal of Aquatic Mammals (in press)

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data ... [more ▼]

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data on the dolphin’s activity patterns were gathered via an Ad Libitum focal group sampling mode accompanying dorsal fin images taken for identification and re-identification of individuals. A total effort of 188 h resulted in 58 h of positive observation of 124 dolphin groups (sightings per unit effort (SPUE) = 0.66 groups/h). Data analysis showed two main activity states for the observed groups, travelling (65%) and foraging (26%). The remaining 9% of the groups were involved in other activity states. The photo-identification effort, which started opportunistically in 2006, resulted in a catalogue of 21 individual dolphins, with a total mean re-identification rate of 9 days (max = 24 days). When comparing these pictures to the existing catalogue of Bahía San Antonio (approximately 200 km west from the study area) dorsal fins of 20 individuals could be positively matched and most (n = 17) could be subsequently re-identified in both areas, indicating their long distance movements along the North Patagonian coast during the austral autumn months. This season coincides with the lowest amount of feeding activity observed in Bahía San Antonio. This study suggests that bottlenose dolphins enter RNE, mainly during autumn, to forage. It appears that the search for food resources may be the trigger for their movement patterns along the North Patagonian coast during this season, at least for certain individuals. More research is needed to accurately confirm this hypothesis. [less ▲]

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See detailClinical usefulness of bone turnover marker concentrations in osteoporosis.
Morris, H. A.; Eastell, R.; Jorgesen, N. R. et al

in Clinica Chimica Acta (in press)

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the ... [more ▼]

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the limitations identified earlier remain, principally in regard to the relationship between BTM and incident fractures. Important data are now available on reference interval values for CTX and PINP across a range of geographic regions and for individual clinical assays. An apparent lack of comparability between current clinical assays for CTX has become evident indicating the possible limitations of combining such data for meta-analyses. Harmonization of units for reporting serum/plasma CTX (ng/L) and PINP (mug/L) is recommended. The development of international collaborations continues with an important initiative to combine BTM results from clinical trials in osteoporosis in a meta-analysis and an assay harmonization program are likely to be beneficial. It is possible that knowledge derived from clinical studies can further enhance fracture risk estimation tools with inclusion of BTM together with other independent risk factors. Further data of the relationships between the clinical assays for CTX and PINP as well as physiological and pre-analytical factors contributing to variability in BTM concentrations are required. [less ▲]

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See detailRepetitive Genres — Spec. issue of Volume ! La revue des musiques populaires
Levaux, Christophe ULg; Pirenne, Christophe ULg

in Volume ! La revue des musiques populaires (in press)

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See detailHigh Resolution postontrast time of flight MR angiography of intracranial perforators at 7.0 Tesla
Harteveld, A; de Cocker, L; Dieleman, N et al

in American Journal of Neuroradiology (in press)

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See detailReview: Implementing biostimulants and biocontrol strategies in the agroecological management of cultivated ecosystems
Le Mire, Géraldine ULg; Nguyen, Minh ULg; Fassotte, Bérénice ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of ... [more ▼]

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of these biostimulant and biocontrol tools for the sustainable management of agricultural practices is also discussed. Special attention is given to the formulation of these products and the network of interactions taking place in cultivated ecosystems [less ▲]

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See detailInfluence of the balls kinematics of axially loaded ball bearings on Coulombic frictional dissipations
Bozet, Jean-Luc ULg; Servais, Christophe ULg

in Journal of Tribology (2017), 139(1),

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact ... [more ▼]

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact balls kinematics has still to be addressed in depth. This paper proposes a new way to calculate the balls kinematics by using a simplified quasi-static approach for dry lubricated and axially loaded ball bearings. This method does not use the classical restrictive race control assumptions. More specifically, the role played by the balls kinematics is emphasized by means of the power dissipated within contacts between balls and races. The need for a correct evaluation of the balls behavior is illustrated by using an example, viz. a ball bearing of cryogenic engine turbopump. Indeed, the dissipated power is one of the main concerns in this particular case. [less ▲]

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See detailLa « personnalité antisociale », antithèse de la psychopathologie
Englebert, Jérôme ULg; Adam, Christophe

in Déviance et Société (2017), 41(1),

L’article propose une réflexion critique et clinique sur la notion de « personnalité antisociale », largement usitée dans le domaine de la nosographie des troubles mentaux et des pratiques « psy- » au ... [more ▼]

L’article propose une réflexion critique et clinique sur la notion de « personnalité antisociale », largement usitée dans le domaine de la nosographie des troubles mentaux et des pratiques « psy- » au sein du système de justice pénale. Notre réflexion débutera par une généalogie du vocable dans différentes versions de la classification psychiatrique, depuis les années cinquante jusqu’aujourd’hui, et plus particulièrement celle faisant autorité du Manuel statistique et diagnostique des troubles mentaux (DSM). L’absence de raisonnement sociologique dans l’usage d’une notion impliquant pourtant la référence au « social » sera discutée ainsi que ses évolutions historiques. Ensuite, la démonstration de l’antithèse que cette notion constitue pour une perspective psychopathologique digne de ce nom – dynamique, compréhensive et phénoménologique – sera développée en six arguments majeurs et plurivoques, tantôt empiriques et cliniques, tantôt théoriques. [less ▲]

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See detailAdresse, opinion et responsabilité : un modèle de la subjectivation en public
Servais, Christine ULg

in Questions de Communication (2017)

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels ... [more ▼]

Cet article interroge la relation entre « publics » et « collectifs » et en propose un modèle de description à caractère phénoménologique. Après un examen des implications politiques des modèles auxquels sont susceptibles de se référer les théories de la réception médiatique, on tente d’élaborer, à partir du travail de Stiegler, de Rancière et de Derrida, une approche de la réception qui permet de décrire à la fois l’émancipation et la domination, cette alternative étant l’un des points de butée des théories de la réception. Le critère déterminant est ici l’adresse, considérée comme la traduction en termes phénoménologiques de l’énonciation. La réception est alors envisagée comme une réponse à une adresse. Cette conception de l’énonciation rend compte de la dimension politique d’une réception médiatique où l’identité sociale est désormais indexée sur notre identité de destinataires de dispositifs médiatique, c’est-à-dire de publics [less ▲]

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See detailLe commun à l'épreuve du conflit : médiation esthétique et expérience de la communauté
Servais, Christine ULg

in Recherches en Communication (2017)

Cet article propose une conception de la médiation culturelle où la notion de médiation est lestée d’un rapport complexe au tiers, rapport susceptible de prendre en compte le conflit que peut constituer ... [more ▼]

Cet article propose une conception de la médiation culturelle où la notion de médiation est lestée d’un rapport complexe au tiers, rapport susceptible de prendre en compte le conflit que peut constituer la prise de position du destinataire auquel s’adressent les dispositifs de médiation. Cette approche de la médiation conserve la distinction entre passage et forçage, ce qui la situe dans un cadre politique. [less ▲]

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See detailThe Tourist on the farm: a 'muddled' image
Dubois, Charline ULg; Cawley, Mary; Schmitz, Serge ULg

in Tourism Management (2017), 59

Agritourism is promoted as a method of offsetting decline in farm incomes, and is defined in different ways which creates difficulties in attracting tourists. The present research contributes to a better ... [more ▼]

Agritourism is promoted as a method of offsetting decline in farm incomes, and is defined in different ways which creates difficulties in attracting tourists. The present research contributes to a better understanding of agritourism, based on evidence in Wallonia (Belgium) and Luxembourg. It does so by studying the image held by four groups of actors: (i) farmers who provide ‘agritourist’ experiences; (ii) promotional organisations; and tourists who both (iii) have and (iv) have not engaged in agritourism. Agritourism is a muddled concept between realities and stakeholder expectations but opportunities exist for targeting particular niche interests. [less ▲]

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See detailAn Analysis of the Interaction Effect between Employee Technical and Emotional Competencies in Emotionally Charged Service Encounters
Delcourt, Cécile ULg; Gremler, Dwayne; De Zanet, Fabrice ULg et al

in Journal of Service Management (2017), 28

Purpose—Customers often experience negative emotions during service experiences. The ways that employees manage customers’ emotions and impressions about whether the service provider is concerned for them ... [more ▼]

Purpose—Customers often experience negative emotions during service experiences. The ways that employees manage customers’ emotions and impressions about whether the service provider is concerned for them in such emotionally charged service encounters (ECSEs) is crucial, considering the criticality of the encounter. Drawing on cognitive appraisal theory, this study proposes that two key competencies—employee emotional competence (EEC) and employee technical competence (ETC)—affect negative customer emotions and customer satisfaction with employee response in ECSEs. Design/methodology—This study relies on a video-based experiment that depicts a customer involved in an ECSE as a service provider delivers bad news to him. The hypothesis tests use a two-way independent analysis of covariance. Results—Both emotional and technical competencies must be displayed to improve the customer experience in an ECSE. When EEC is low, ETC does not decrease negative customer emotions or increase customer satisfaction with employee response. When EEC is high, ETC instead has a significant impact on both customer outcomes. Practical implications—Managers must train employees to develop both technical and emotional competencies. Employees who demonstrate only one type cannot temper customers’ emotions or enhance their perceptions of the employees’ response as well as can those strong in both competencies. Originality/value—Using a video-based experiment, this study examines the moderating role of EEC in the relationship between ETC and two key aspects of the customer experience in an ECSE (negative customer emotions and customer satisfaction with employee responses) following the delivery of bad news. [less ▲]

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See detailIconic virtues of diagrams. Peirce on ampliative reasoning
Leclercq, Bruno ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (2017)

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See detailComprehension of an organosolv process for lignin extraction on Festuca arundinacea and monitoring of the cellulose degradation
Schmetz, Quentin ULg; Maniet, Guillaume ULg; Jacquet, Nicolas ULg et al

in Industrial Crops and Products (2016), 94

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving ... [more ▼]

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving lignocellulosic biomass to produce bio-based materials and fuels. This study focuses on the comprehension of an organosolv treatment designed to break the complex lignocellulosic structure for high purity lignin extraction from tall fescue (Festuca arundinacea Schreb.). This grass benefits from an increasing interest in Western Europe and has been suggested as feedstock for biorefinery. However, its use as material for high purity lignin production has not been determined yet. Ethanol/water, 92/8% [v/v] with H2SO4 0.32 M was investigated at pilot scale under conventional heating (5 °C min−1 during 30 min and stabilized at 148 °C for 5 min). Precipitated lignin were analyzed as well as the composition of side-stream products (recovered cellulosic pulp and the aqueous hydrolysate). Lignin has been recovered at a purity level of 90% with a yield of 60%. The main contaminants were nitrogen containing compounds and degraded hemicelluloses. 2D-HSQC NMR (Two Dimension-Heteronuclear Single Quantum Correlation Nuclear Magnetic Resonance) revealed a co-extraction of ferulates and coumarates function as well as arabinoxylan. Cellulose was recovered at 53% purity with 60% yield. The conditions appear to be too harsh for tall fescue and led to significant amount of cellulose degradation. A process using a lower alcohol concentration will be developed to provide better yields of both cellulose and lignin. [less ▲]

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See detailAging of monolithic zirconia dental prostheses: Protocol for a 5-year prospective clinical study using ex vivo analyses
KOENIG, Vinciane ULg; Wulfman, Claudine; DERBANNE, Mathieu et al

in Contemporary Clinical Trials Communication (2016), 4

Background: Recent introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) monolithic zirconia dental prostheses raises the issue of material low thermal degradation (LTD), a ... [more ▼]

Background: Recent introduction of computer-aided design/computer-aided manufacturing (CAD/CAM) monolithic zirconia dental prostheses raises the issue of material low thermal degradation (LTD), a wellknown problem with zirconia hip prostheses. This phenomenon could be accentuated by masticatory mechanical stress. Until now zirconia LTD process has only been studied in vitro. This work introduces an original protocol to evaluate LTD process of monolithic zirconia prostheses in the oral environment and to study their general clinical behavior, notably in terms of wear. Methods/design: 101 posterior monolithic zirconia tooth elements (molars and premolars) are included in a 5-year prospective clinical trial. On each element, several areas between 1 and 2 mm2 (6 on molars, 4 on premolars) are determined on restoration surface: areas submitted or non-submitted to mastication mechanical stress, glazed or non-glazed. Before prosthesis placement, ex vivo analyses regarding LTD and wear are performed using Raman spectroscopy, SEM imagery and 3D laser profilometry. After placement, restorations are clinically evaluated following criteria of the World Dental Federation (FDI), complemented by the analysis of fracture clinical risk factors. Two independent examiners perform the evaluations. Clinical evaluation and ex vivo analyses are carried out after 6 months and then each year for up to 5 years. Discussion: For clinicians and patients, the results of this trial will justify the use of monolithic zirconia restorations in dental practice. For researchers, the originality of a clinical study including ex vivo analyses of material aging will provide important data regarding zirconia properties. [less ▲]

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See detailNouveaux textes littéraires du scribe Amennakhte (et autres ostraca relatifs au scribe de la Tombe)
Dorn, Andreas ULg; Polis, Stéphane ULg

in Bulletin de l'Institut Français d'Archéologie Orientale (2016), 116

Cet article est le premier d’une série de contributions consacrées à la publication de documents inédits conservés à l’Institut Français d’Archéologie Orientale et ayant pour point commun le fait d’être ... [more ▼]

Cet article est le premier d’une série de contributions consacrées à la publication de documents inédits conservés à l’Institut Français d’Archéologie Orientale et ayant pour point commun le fait d’être, plus ou moins directement, liés au fameux scribe de la Tombe Amennakhte, fils d’Ipouy. L’objectif est de fournir les matériaux de base qui seront nécessaires à la réalisation de projets de plus grande ampleur, telles une étude micro-historique autour de l’individu en question et une analyse globale de la production textuelle d’un scribe de Deir el-Médineh à la 20e dynastie. Les six ostraca publiés ici appartiennent au fonds des ostraca dits « littéraires » de l’IFAO. Les deux premiers documents sont assurément les plus remarquables dans la mesure où ils viennent enrichir le nombre des textes littéraires ‘signés’ par le scribe Amennakhte. [less ▲]

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See detailAncient Egyptian texts in contexts. Towards a conceptual data model (the Thot Data Model - TDM)
Polis, Stéphane ULg; Razanajao, Vincent ULg

in Bulletin of the Institute of Classical Studies (2016), 59(2),

In this paper, we propose a conceptual data model that could be the basis for future implementations of databases and digital corpuses of Ancient Egyptian texts that fully integrate the material ... [more ▼]

In this paper, we propose a conceptual data model that could be the basis for future implementations of databases and digital corpuses of Ancient Egyptian texts that fully integrate the material dimensions of writing. The types of metadata that can be used for documenting the elements and relationships of this model are discussed and the resources (URIs) available for its online implementation (in the perspective of the ‘linked open data’ movement) are examined. [less ▲]

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See detailProtein encapsulation and release from PEO-b-polyphosphoester templated calcium carbonate particles
Ergül, Zeynep ULg; Cordonnier, Thomas; Debuigne, Antoine ULg et al

in International Journal of Pharmaceutics (2016), 513

Calcium carbonate particles are promising candidates as proteins carriers for their controlled delivery in the body. The present paper aims at investigating the protein encapsulation by in situ ... [more ▼]

Calcium carbonate particles are promising candidates as proteins carriers for their controlled delivery in the body. The present paper aims at investigating the protein encapsulation by in situ precipitation of calcium carbonate particles prepared by a process based on supercritical CO2 and using a new type of degradable well-defined double hydrophilic block copolymers composed of poly(ethylene oxide) and polyphosphoester blocks acting as templating agent for the calcium carbonate. For this study, lysozyme was chosen as a model for therapeutic protein for its availability and ease of detection. It was found that by this green process, loading into the CaCO3 microparticles with a diameter about 2 mm can be obtained as determined by scanning electron microscopy. A protein loading up to 6.5% active lysozyme was measured by a specific bioassay (Micrococcus lysodeikticus). By encapsulating fluorescent-labelled lysozyme (lysozyme-FITC), the confocal microscopy images confirmed its encapsulation and suggested a core–shell distribution of lysozyme into CaCO3, leading to a release profile reaching a steady state at 59% of release after 90 min. [less ▲]

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See detailCarbon balance of an intensively grazed grassland in southern Belgium
Gourlez de la Motte, Louis ULg; Jérôme, Elisabeth; Mamadou, Ossénatou et al

in Agricultural and Forest Meteorology (2016), 228-229

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See detailLoadbearing capacity criteria in fire resistance testing
Dumont, Fabien ULg; Wellens, Eric ULg; Gernay, Thomas ULg et al

in Materials and Structures (2016), 49(11), 4565-4581

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the ... [more ▼]

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the loadbearing performance. This article analyzes the implications of the present conflict between the standard for testing and the standard for classification. The prescribed criteria for loadbearing performance are related to the exceedance of deflection and rate of deflection thresholds. A database of 46 fire resistance tests performed at the University of Liege is collected that contains the time at which these thresholds are reached in fire tests with different typologies of elements (walls, floors, columns and beams). Then, the loadbearing performance (and hence the fire resistance rating) can be derived according to the two standards. The evolutions of deflection and rate of deflection during the tests are also analyzed to gain a better understanding of the adequacy of the standards. The selection of one or the other standard affects the time at which “failure” is deemed to occur in fire tests. Statistically speaking, the difference in terms of failure time that results from using one or the other standard has a 25% probability to exceed 10%. In certain cases, this results in a difference in fire resistance rating; this was observed for 3 of the analyzed tests. The apparent contradiction in two codes in application has potential practical implications and therefore needs to be solved. The article suggests some guidelines for defining homogenized and consistent criteria. [less ▲]

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See detailThe construction of religion as a ‘public problem’. The emergence of Islam in the public space during Tunisia’s transition to democracy (2011--2014)
Nachi, Mohamed ULg

in Social Sciences Information = Information sur les Sciences Sociales (2016), 55(4),

La construction de l'islam en "problème public" au cours de la période de transition démocratique.

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See detailMeasurements of reference ISO nozzles by high-speed imaging
De Cock, Nicolas ULg; Massinon, Mathieu ULg; Nuyttens, David et al

in Crop Protection (2016), 89

Agricultural spray characteristics determine the efficiency of a pesticide application because size and velocity affect droplet trajectory and impact behavior. At present, the relevance of different ... [more ▼]

Agricultural spray characteristics determine the efficiency of a pesticide application because size and velocity affect droplet trajectory and impact behavior. At present, the relevance of different characterization techniques remains controversial since discrepancies may be significant between measurements performed in different laboratories. A digital image acquisition technique and analysis algorithm is proposed for droplet size and velocimetry measurements as an alternative to well-established techniques such as the Phase Doppler Particle Analyzer (PDPA) or laser diffraction spectrometry (LDS). The algorithm requires double exposed shadow images acquired in a back-lighted arrangement with a Particle Image Velocimetry (PIV) camera and a pulsed light emitting diode (LED). Spatial illumination heterogeneities are corrected by subtracting from each image a mean background acquired on several images without any particle. The algorithm accuracy is ensured by the rejection of out-of-focus particles using a focus parameter depending on gradient intensity at the particle edges. Thresholds for focus particle selection were determined by studying the evolution of the focus parameter and the error on particle size measurements from images containing droplets with uniform size at various distance of the object plane. Selected droplets were identified on both pairs of images to determine their size and velocity. Droplet size distributions were corrected to account for the uneven sampling probability caused by the volumetric method. Droplet size distributions of a set of reference nozzle/pressure combinations defined in the ISO/DIS 25358 were measured. The image technique was able to distinguish each of the reference sprays well. Comparison with PDPA measurements showed that the imaging technique tends to measure an equivalent Dv50, a lower Dv10 and a higher Dv90 leading therefore to a higher relative span factor. Velocity measurements showed good agreement between both techniques except for one nozzle/pressure combination. [less ▲]

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See detailTransition to democracy in Tunisia. Learning about citizenship in a national and transnational context
Nachi, Mohamed ULg

in Social Sciences Information = Information sur les Sciences Sociales (2016), 55(4),

La transition en Tunisie a constitué un moment fort d'apprentissage de la démocratie.

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See detailSU(3) Clebsch-Gordan coefficients at large $N_c$
Stancu, Floarea ULg

in Nuclear Physics A (2016), 945

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic ... [more ▼]

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic formulae derived by Hecht in 1965 in the context of nuclear physics. This is valid for irreducible representations with multiplicity one in the corresponding Clebsch-Gordan series. For multiplicity two, Hecht has proposed an alternative which can provide correct $1/N_c$ sub-leading orders in large $N_c$ studies. [less ▲]

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See detailA large strain hyperelastic viscoelastic-viscoplastic-damage constitutive model based on a multi-mechanism non-local damage continuum for amorphous glassy polymers
Nguyen, Van Dung ULg; Lani, Frédéric; Pardoen, Thomas et al

in International Journal of Solids and Structures (2016), 96

A large strain hyperelastic phenomenological constitutive model is proposed to model the highly nonlinear, rate-dependent mechanical behavior of amorphous glassy polymers under isothermal conditions. A ... [more ▼]

A large strain hyperelastic phenomenological constitutive model is proposed to model the highly nonlinear, rate-dependent mechanical behavior of amorphous glassy polymers under isothermal conditions. A corotational formulation is used through the total Lagrange formalism. At small strains, the viscoelastic behavior is captured using the generalized Maxwell model. At large strains beyond a viscoelastic limit characterized by a pressure-sensitive yield function, which is extended from the Drucker-Prager one, a viscoplastic region follows. The viscoplastic flow is governed by a non-associated Perzyna-type flow rule incorporating this pressure-sensitive yield function and a quadratic flow potential in order to capture the volumetric deformation during the plastic process. The stress reduction phenomena arising from the post-peak plateau and during the failure stage are considered in the context of a continuum damage mechanics approach. The post-peak softening is modeled by an internal scalar, so-called softening variable, whose evolution is governed by a saturation law. When the softening variable is saturated, the rehardening stage is naturally obtained since the isotropic and kinematic hardening phenomena are still developing. Beyond the onset of failure characterized by a pressure-sensitive failure criterion, the damage process leading to the total failure is controlled by a second internal scalar, so-called failure variable. The final failure occurs when the failure variable reaches its critical value. To avoid the loss of solution uniqueness when dealing with the continuum damage mechanics formalism, a non-local implicit gradient formulation is used for both the softening and failure variables, leading to a multi-mechanism non-local damage continuum. The pressure sensitivity considered in both the yield and failure conditions allows for the distinction under compression and tension loading conditions. It is shown through experimental comparisons that the proposed constitutive model has the ability to capture the complex behavior of amorphous glassy polymers, including their failure. [less ▲]

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See detailTowards a large scale aqueous sol-gel synthesis of doped TiO2: Study of various metallic dopings for the photocatalytic degradation of p-nitrophenol
Mahy, Julien ULg; Lambert, Stéphanie ULg; Léonard, Géraldine ULg et al

in Journal of Photochemistry and Photobiology A : Chemistry (2016), 329

In this paper, an easy aqueous sol-gel synthesis developed previously by Mahy et al. [J. Sol-Gel Sci. Technol. (2016)] is adapted to produce highly active TiO2 catalysts doped with Fe3+, Ag+, Cu2+, Zn2 ... [more ▼]

In this paper, an easy aqueous sol-gel synthesis developed previously by Mahy et al. [J. Sol-Gel Sci. Technol. (2016)] is adapted to produce highly active TiO2 catalysts doped with Fe3+, Ag+, Cu2+, Zn2+, Cr3+, Al3+, Mn2+, and Co2+ ions and Pt metallic nanoparticles. Samples are characterized by inductively coupled plasma–atomic emission spectroscopy (ICP-AES), X-ray diffraction (XRD), Mössbauer spectroscopy, transmission electron microscopy (TEM), nitrogen adsorption–desorption measurements and diffuse reflectance spectroscopy measurements. Results show that the samples are composed of anatase-brookite TiO2 nanoparticles with a spherical shape and mean diameter of around 5-8 nm and a surface area of between about 150 - 250 m2 g-1. In each doped sample, the dopant is present in the form added during the synthesis, given that the sample has not undergone any particular treatment. Photoactivity tests show improvement in catalyst activity for Fe3+, Ag+, Cu2+, Zn2+, and Al3+ ion and Pt metallic nanoparticle dopants, while a decrease of activity is obtained for Cr3+, Mn2+ and Co2+ ion dopants. For some dopants, the activity of TiO2 doped with metallic ions and synthesized from the aqueous sol-gel process is equal or superior to the activity of the commercial photocatalyst Degussa P25. Some mechanisms are proposed to explain these modifications of activity with doping. Furthermore, cost comparison at laboratory scale showed that Zn and Cu nitrate salt dopings are clearly less expensive for a halogen light (UV/visible) or low energy light enhanced catalyst and may be considered for industrial applications. Using this method, a large scale Zn-doped TiO2 photocatalyst is synthesized with properties homologous to the lab-scale product. Results show that the aqueous sol-gel synthesis developed previously can be easily adapted for doping in order to produce an up-scalable synthesis. [less ▲]

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See detailL’étau et le réseau. Recompositions des contextes de travail des équipes de direction pénitentiaire
Dubois, Christophe ULg

in Justice et sécurité/Justitie en veiligheid (2016), 7

Résumé : En parcourant les nombreuses études qui décrivent et analysent, depuis plus de vingt ans, le fonctionnement des organisations et des politiques pénitentiaires, trois questions semblent avoir ... [more ▼]

Résumé : En parcourant les nombreuses études qui décrivent et analysent, depuis plus de vingt ans, le fonctionnement des organisations et des politiques pénitentiaires, trois questions semblent avoir jusqu’ici suscité un moindre intérêt scientifique : qui dirige ces organisations ? En quoi consiste le travail des équipes de direction ? Quelle position les membres de ces équipes occupent-ils dans le système organisationnel et politique pénitentiaire belge ? Cet article apporte quelques éléments de réponse à ces questions tout en éclairant les recompositions des contextes de travail des équipes de direction pénitentiaire. Cet éclairage souligne la nécessité de définir politiquement et avec les principaux intéressés un processus de professionnalisation de la fonction qu’ils exercent. [less ▲]

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See detailL’approche sémiotique de Charles Goodwin : langage visuel, énonciation et diagramme
Dondero, Maria Giulia ULg

in Tracés. Revue de Sciences Humaines (2016), 3(automne),

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by ... [more ▼]

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by exploring the Goodwin’s notational system (transcription of exchanges) from the point of view of its constituent units. Secondly, I consider the meeting points between Goodwin’s concept of the substrate and Fontanille’s enunciative praxis in order to examine the dynamic relationship between sedimentation and transformation. Finally, I analyse the concept of diagrammatic reasoning by elaborating on the example of the geologists’ “first inscriptions” studied by Goodwin. The form of diagrammatic reasoning examined here functions as a discovery device that exemplifies the dynamics of sedimentation and novelty, and it can thus be studied in the framework of Goodwin’s transcription practices. [less ▲]

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See detailThe link between self-perceptions of aging, cancer view and physical and mental health of older people with cancer: A cross-sectional study
Schroyen, Sarah ULg; Marquet, Manon ULg; Jerusalem, Guy ULg et al

in Journal of Geriatric Oncology (2016)

Objectives Older people may suffer from stigmas linked to cancer and aging. Although some studies suggested that a negative view of cancer may increase the level of depression, such an association has ... [more ▼]

Objectives Older people may suffer from stigmas linked to cancer and aging. Although some studies suggested that a negative view of cancer may increase the level of depression, such an association has never been studied in the elderly population. Similarly, even though it is established that a negative self-perception of aging has deleterious consequences on mental and physical health in normal aging, the influence in pathological contexts, such as oncology, has not been studied. The main aim of this study is thus to analyze the effect of these two stigmas on the health of elderly oncology patients. Materials and Methods 101 patients suffering from a cancer (breast, gynecological, lung or hematological) were seen as soon as possible after their diagnosis. Their self-perception of age, cancer view and health (physical and mental) was assessed. Results Multiple regressions showed that patients with a more negative self-perception of aging and/or more negative cancer view reported poorer global health. We also observed that negative self-perception of aging was associated with worse physical and mental health, whereas negative cancer views were only linked to worse mental health. No interaction was observed between these two stigmas, suggesting that their action is independent. Conclusion Older patients with cancer face double stigmatization, due to negative self-perception of aging and cancer, and these stigmas have impacts on global and mental health. Self-perception of aging is also linked to physical health. Longitudinal studies will be necessary to analyze the direction of the association between this double stigmatization and health. [less ▲]

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See detailAcoustic indices provide information on the status of coral reefs: an example from Moorea Island in the South Pacific
Bertucci, Frédéric; Parmentier, Eric ULg; Lecellier, Gaël et al

in Scientific Reports (2016), 6(33326), 1-9

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See detailEffects of equine chorionic gonadotropin (eCG) on the sexual behaviour and ovulatory characteristics of female african N'Dama cattle.
Okouyi, M.W. Marcel; Hanzen, Christian ULg

in Revue de Médecine Vétérinaire (2016), 167(7-8), 211-215

This paper evaluated the effects of eCG on the characteristics of oestrus and ovulation after heifers and cows had been synchronised following vaginal administration of progesterone for seven days ... [more ▼]

This paper evaluated the effects of eCG on the characteristics of oestrus and ovulation after heifers and cows had been synchronised following vaginal administration of progesterone for seven days (Controlled Internal Drug Released) and a PGF2α injection two days after the end of treatment. The animals were randomly split into a non-treated control group (n=26) and four groups with increasing doses of eCG: 300 IU (n=25), 400 IU (n=24), 500 IU (n=23) and 600 IU (n=23), which were injected on the day of CIDR withdrawal. The animals were then followed (24 hours a day) for six days. Oestrus was confirmed on the basis of identifying 'standing oestrus', i.e., when the cow stood to be mounted. Seven to ten days after the CIDR® was withdrawn, the animals were slaughtered, and their ovaries were examined to identify and count the number of follicular and/or luteal structures. The onset of heat was 48.6 ± 5.3 hours after eCG injection, and the average length of oestrus was 9.9 ± 2 hours. The eCG dosage had no significant effect on these two parameters. In contrast, the observed rate of oestrus was significantly (p<0.05) higher in animals that had been treated (70.8 to 84.0%) in comparison with animals that had not been treated (50%). Similarly, the ovulation rate was significantly (p<0.05) higher in treated animals (88.0 to 100%) than in untreated animals (73.1%). The percentage of animals that presented multiple ovulations increased significantly (p <0.001) with the dosage of eCG administered (4.5% to 36.4%). [less ▲]

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See detailAxIOM: Amphipod crustaceans from insular Posidonia oceanica seagrass meadows
Michel, Loïc ULg; Sturaro, Nicolas ULg; Heughebaert, André et al

in Biodiversity Data Journal (2016), 4

Background The Neptune grass, Posidonia oceanica (L.) Delile, 1813, is the most widespread seagrass of the Mediterranean Sea. This foundation species forms large meadows that, through habitat and trophic ... [more ▼]

Background The Neptune grass, Posidonia oceanica (L.) Delile, 1813, is the most widespread seagrass of the Mediterranean Sea. This foundation species forms large meadows that, through habitat and trophic services, act as biodiversity hotspots. In Neptune grass meadows, amphipod crustaceans are one of the dominant groups of vagile invertebrates, forming an abundant and diverse taxocenosis. They are key ecological components of the complex, pivotal, yet critically endangered Neptune grass ecosystems. Nevertheless, comprehensive qualitative and quantitative data about amphipod fauna found in Mediterranean Neptune grass meadows remain scarce, especially in insular locations. New information Here, we provide in-depth metadata about AxIOM, a sample-based dataset published on the GBIF portal. AxIOM is based on an extensive and spatially hierarchized sampling design with multiple years, seasons, day periods, and methods. Samples were taken along the coasts of Calvi Bay (Corsica, France) and of the Tavolara-Punta Coda Cavallo Marine Protected Area (Sardinia, Italy). In total, AxIOM contains 187 samples documenting occurrence (1775 records) and abundance (10720 specimens) of amphipod crustaceans belonging to 72 species spanning 29 families. The dataset is available at http://ipt.biodiversity.be/resource?r=axiom. [less ▲]

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See detailApplication of GRACE to the assessment of model-based estimates of monthly Greenland Ice Sheet mass balance (2003–2012)
Schlegel, N.; Wiese, D.; Larour, E. et al

in Cryosphere (The) (2016), 10

Quantifying the Greenland Ice Sheet's future contribution to sea level rise is a challenging task that requires accurate estimates of ice sheet sensitivity to climate change. Forward ice sheet models are ... [more ▼]

Quantifying the Greenland Ice Sheet's future contribution to sea level rise is a challenging task that requires accurate estimates of ice sheet sensitivity to climate change. Forward ice sheet models are promising tools for estimating future ice sheet behavior, yet confidence is low because evaluation of historical simulations is challenging due to the scarcity of continental-wide data for model evaluation. Recent advancements in processing of Gravity Recovery and Climate Experiment (GRACE) data using Bayesian-constrained mass concentration ("mascon") functions have led to improvements in spatial resolution and noise reduction of monthly global gravity fields. Specifically, the Jet Propulsion Laboratory's JPL RL05M GRACE mascon solution (GRACE_JPL) offers an opportunity for the assessment of model-based estimates of ice sheet mass balance (MB) at ∼ 300 km spatial scales. Here, we quantify the differences between Greenland monthly observed MB (GRACE_JPL) and that estimated by state-of-the-art, high-resolution models, with respect to GRACE_JPL and model uncertainties. To simulate the years 2003–2012, we force the Ice Sheet System Model (ISSM) with anomalies from three different surface mass balance (SMB) products derived from regional climate models. Resulting MB is compared against GRACE_JPL within individual mascons. Overall, we find agreement in the northeast and southwest where MB is assumed to be primarily controlled by SMB. In the interior, we find a discrepancy in trend, which we presume to be related to millennial-scale dynamic thickening not considered by our model. In the northwest, seasonal amplitudes agree, but modeled mass trends are muted relative to GRACE_JPL. Here, discrepancies are likely controlled by temporal variability in ice discharge and other related processes not represented by our model simulations, i.e., hydrological processes and ice–ocean interaction. In the southeast, GRACE_JPL exhibits larger seasonal amplitude than predicted by the models while simultaneously having more pronounced trends; thus, discrepancies are likely controlled by a combination of missing processes and errors in both the SMB products and ISSM. At the margins, we find evidence of consistent intra-annual variations in regional MB that deviate distinctively from the SMB annual cycle. Ultimately, these monthly-scale variations, likely associated with hydrology or ice–ocean interaction, contribute to steeper negative mass trends observed by GRACE_JPL. Thus, models should consider such processes at relatively high (monthly-to-seasonal) temporal resolutions to achieve accurate estimates of Greenland MB. [less ▲]

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See detailSeasonal variability of surface and column carbon monoxide over megacity Paris, high-altitude Jungfraujoch and Southern Hemispheric Wollongong stations
Té, Y; Jeseck, P; Franco, Bruno ULg et al

in Atmospheric Chemistry and Physics (2016), 16

This paper studies the seasonal variation of surface and column CO at three different sites (Paris, Jungfraujoch and Wollongong), with an emphasis on establishing a link between the CO vertical ... [more ▼]

This paper studies the seasonal variation of surface and column CO at three different sites (Paris, Jungfraujoch and Wollongong), with an emphasis on establishing a link between the CO vertical distribution and the nature of CO emission sources. We find the first evidence of a time lag between surface and free tropospheric CO seasonal variations in the Northern Hemisphere. The CO seasonal variability obtained from the total columns and free tropospheric partial columns shows a maximum around March–April and a minimum around September–October in the Northern Hemisphere (Paris and Jungfraujoch). In the Southern Hemisphere (Wollongong) this seasonal variability is shifted by about 6 months. Satellite observations by the IASI–MetOp (Infrared Atmospheric Sounding Interferometer) and MOPITT (Measurements Of Pollution In The Troposphere) instruments confirm this seasonality. Ground-based FTIR (Fourier transform infrared) measurements provide useful complementary information due to good sensitivity in the boundary layer. In situ surface measurements of CO volume mixing ratios at the Paris and Jungfraujoch sites reveal a time lag of the near-surface seasonal variability of about 2 months with respect to the total column variability at the same sites. The chemical transport model GEOS-Chem (Goddard Earth Observing System chemical transport model) is employed to interpret our observations. GEOS-Chem sensitivity runs identify the emission sources influencing the seasonal variation of CO. At both Paris and Jungfraujoch, the surface seasonality is mainly driven by anthropogenic emissions, while the total column seasonality is also controlled by air masses transported from distant sources. At Wollongong, where the CO seasonality is mainly affected by biomass burning, no time shift is observed between surface measurements and total column data. [less ▲]

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See detailMacro- and near-mesoporous monoliths by medium internal phase emulsion polymerization: a systematic study
Mathieu, Kevin ULg; Jérôme, Christine ULg; Debuigne, Antoine ULg

in Polymer (2016), 99

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were ... [more ▼]

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were tested as stabilizers for water-in-oil medium internal phase emulsion (MIPE) templating polymerization and the formation of polyMIPEs with controlled morphology. Aside from the structure of the emulsion stabilizer, several parameters susceptible to influence the size of the cavities and the interconnectivity of the porous monoliths were probed including the choice of the comonomers, treatment of the emulsion by ultrasound, the use of controlled radical polymerization method for the network formation as well as interfacial initiation. Interconnected cellular monoliths were produced. The polymerization of the ultrasonicated water-in-ethylhexylacrylate/divinylbenzene MIPE notably led to near-mesoporous open-cell material. Mechanical properties and specific surface areas of the polyMIPEs were also investigated and discussed. [less ▲]

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See detailX-ray emission from interacting wind massive binaries: A review of 15 years of progress
Rauw, Grégor ULg; Nazé, Yaël ULg

in Advances in Space Research (2016), 58

Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind ... [more ▼]

Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind interaction zone located between the stars. With the advent of the current generation of X-ray observatories, the phenomenon could be studied in much more detail. In this review, we highlight the progress that has been achieved in our understanding of the phenomenon over the last 15 years, both on theoretical and observational grounds. All these studies have paved the way for future investigations using the next generation of X-ray satellites that will provide crucial information on the X-ray emission formed in the innermost part of the wind-wind interaction. [less ▲]

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See detailThe cardiovascular impact of intense eccentric isokinetic exercise versus aerobic treadmill running
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; LAURENT, Terry ULg et al

in Isokinetics & Exercise Science (2016), 24(3), 201-208

BACKGROUND: Regular physical activity is an important health factor, but intense physical stress can increase the risk of heart disease. OBJECTIVE: Our aim was to determine the potential cardiac ... [more ▼]

BACKGROUND: Regular physical activity is an important health factor, but intense physical stress can increase the risk of heart disease. OBJECTIVE: Our aim was to determine the potential cardiac repercussions of, and the oxidative stress resulting from a maximal eccentric isokinetic exercise and a 1-hour treadmill run at 75% ˙V O2 max (maximal exercise done 6 weeks before). METHODS: Twelve young sedentary healthy subjects randomly performed two tests separated by 6 weeks: 1) 3 sets of 30 maximal eccentric isokinetic contractions of the quadriceps; 2) a 1-hour running on treadmill at 75% ˙V O2 max. We drew blood samples just before each exercise (T1), and just after (T2), 3 hours after (T3), and 24 hours after (T4) the end of each exercise to measure cardiac and oxidative stress biomarkers. RESULTS: In the running group, we observed significant differences for myoglobin (T3: 145 ± 80 μg/L), creatinine kinase (T4: 593 ± 350 mg/L), oxidized glutathione (T2: 22 ± 15.6 μmol/L), and highly sensitive cardiac troponin T, (T3: 0.051 ± 0.038 ng/mL). In the isokinetic group, we observed significant differences for myoglobin (T3:1419 ± 2533 mg/L), creatine kinase (3303 ± 7159 mg/L), and oxidized glutathione (T4:24 ± 14 μmol/L). Between isokinetic exercise and running, we observed significant differences for uric acid (p < 0.05, running > eccentric), myoglobin (p < 0.05, ditto), NT-proBNP (p < 0.05, ditto), hsTnT (p < 0.01, ditto), and oxidized glutathione (p < 0.05). CONCLUSIONS: As cardiac biomarkers appear practically unmodified after the isokinetic exercise, despite the considerable oxidative stress, we suggest that the application of intense maximal eccentric isokinetic exercise, when indicated, should be safe for most patients including those whose cardiac status is unknown. On the other hand, the increase in cardiac biomarkers observed after running, could reflect leakage of these biomarkers from the cytosolic pool of cardiac cells, linked to membrane damage, rather than the result of a major injury and hence running is supposed to be a safe practice. However, since sudden death during running has been previously described, assesment of the cardiac biomarkers and a follow-up by a sport doctor is important especially if there is a cardiac family history. [less ▲]

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See detailOxytocin in survivors of childhood-onset craniopharyngioma
Daubenbüchel, Anna; Hoffmann, Anika; Eveslage, Maria et al

in Endocrine (2016)

Quality of survival of childhood-onset cranio- pharyngioma patients is frequently impaired by hypotha- lamic involvement or surgical lesions sequelae such as obesity and neuropsychological deficits ... [more ▼]

Quality of survival of childhood-onset cranio- pharyngioma patients is frequently impaired by hypotha- lamic involvement or surgical lesions sequelae such as obesity and neuropsychological deficits. Oxytocin, a pep- tide hormone produced in the hypothalamus and secreted by posterior pituitary gland, plays a major role in regula- tion of behavior and body composition. In a cross- sectional study, oxytocin saliva concentrations were ana- lyzed in 34 long-term craniopharyngioma survivors with and without hypothalamic involvement or treatment- related damage, recruited in the German Childhood Cra- niopharyngioma Registry, and in 73 healthy controls, attending the Craniopharyngioma Support Group Meeting 2014. Oxytocin was measured in saliva of craniophar- yngioma patients and controls before and after standar- dized breakfast and associations with gender, body mass index, hypothalamic involvement, diabetes insipidus, and irradiation were analyzed. Patients with preoperative hypothalamic involvement showed similar oxytocin levels compared to patients without hypothalamic involvement and controls. However, patients with surgical hypotha- lamic lesions grade 1 (anterior hypothalamic area) pre- sented with lower levels (p = 0.017) of oxytocin under fasting condition compared to patients with surgical lesion of posterior hypothalamic areas (grade 2) and patients without hypothalamic lesions (grade 0). Craniophar- yngioma patients’ changes in oxytocin levels before and after breakfast correlated (p = 0.02) with their body mass index. Craniopharyngioma patients continue to secrete oxytocin, especially when anterior hypothalamic areas are not involved or damaged, but oxytocin shows less varia- tion due to nutrition. Oxytocin supplementation should be explored as a therapeutic option in craniopharyngioma patients with hypothalamic obesity and/or behavioral pathologies due to lesions of specific anterior hypotha- lamic areas. Clinical trial number: KRANIOPHAR- YNGEOM 2000/2007(NCT00258453; NCT01272622). [less ▲]

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See detailThe Case : Acute renal failure and refractory hyponatremia
denis, Chloé; JADOT, Virginie ULg; BOUQUEGNEAU, Antoine ULg et al

in Kidney International (2016), 90

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See detailEnonciation et modes d'existence
Dondero, Maria Giulia ULg

in Nouveaux Actes Sémiotiques (2016)

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique ... [more ▼]

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique francophone contemporaine qu’à la base de la réflexion de Bruno Latour, des années 1970 jusqu’à présent . Notre propos se déploie en deux moments : dans un premier temps, nous revenons sur l’article "Petite Philosophie de l’énonciation" (1998), et nous en suivons le développement dans l’Enquête sur les modes d’existence (2012). Dans un second temps, nous réalisons une rapide archéologie de la théorie de l’énonciation dans la sémiotique contemporaine, afin de mettre en lumière les liens entre différentes traditions sémiotiques et la théorie latourienne. Plus précisément, nous nous attachons aux propositions récentes de Jacques Fontanille et de Claudio Paolucci, en prenant également en considération les contributions d’Umberto Eco et Patrizia Violi. Il s’agit de voir comment les sémioticiens peuvent tirer profit de la théorie latourienne des modes d’existence et vice versa. [less ▲]

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See detailLes Nouveaux Liégeois. Migrations et Transformations Urbaines
Lafleur, Jean-Michel ULg; Stangherlin, Gregor

in Dérivations (2016), (3), 194-203

Dans cet article, nous proposons de discuter la migration contemporaine sur le territoire de la Ville de Liège. Cette discussion repose pour l’essentiel sur une analyse des données statistiques ... [more ▼]

Dans cet article, nous proposons de discuter la migration contemporaine sur le territoire de la Ville de Liège. Cette discussion repose pour l’essentiel sur une analyse des données statistiques disponibles et une revue de la littérature scientifique produite sur les migrations à Liège ces dernières années. Nous commençons donc par une description des grandes évolutions démographiques sur le territoire de la ville depuis 1991 pour insister ensuite sur les effets de la migration dans cinq quartiers de la ville. Cette première partie souligne le rôle essentiel que joue la migration dans la croissance démographique observée ces dix dernières années à Liège. Ensuite, nous examinons la présence étrangère sur le territoire de la ville selon les 5 dimensions fréquemment citées dans les débats sur l’intégration des populations étrangères : emploi, logement, éducation, socio-culturelle et politique. [less ▲]

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See detailHousing Quality as Environmental Inequality: The Case of Wallonia, Belgium
Lejeune, Zoé ULg; Xhignesse, Guillaume ULg; Kryvobokov, Marko et al

in Journal of Housing and the Built Environment (2016), 31(3), 495-512

First in the USA and then in many other countries, scholarship on environmental inequality has sought to shed light on the unequal environmental conditions borne by poor people and ethnic minorities, and ... [more ▼]

First in the USA and then in many other countries, scholarship on environmental inequality has sought to shed light on the unequal environmental conditions borne by poor people and ethnic minorities, and to challenge public policies and their unjust impacts on those target groups. Housing quality, especially the indoor characteristics of homes, offers an innovative perspective in this field of research. In previous research on environmental inequality in the Walloon context, housing quality has been proven to be a major determinant of quality of life and environmental well-being. This paper analyses housing quality through a twofold approach: through indoor characteristics on the one hand, and outdoor subjective and objective externalities on the other. It reveals the disparities between the most deprived and the wealthiest segments of the population. The evidence for this study is based on a housing quality survey carried out in 2012 and 2013 on 6,018 households in Wallonia (Belgium). The key findings are that poor people are found to live in housing of lower quality, in densely populated neighbourhoods and those with mixed use, with compensating amenities provided at the local level. Moreover, consistent with environmental inequality scholarship, deprived households are found to bear the burden of environmental degradation outside the home. People live in areas with poorer air quality, but are found to benefit from greater access to green spaces. The results of the survey reveal an interesting point concerning the environmental inequality literature; the interior features of housing are found to differ more widely between deprived and wealthier people than the surrounding environment does. [less ▲]

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See detailL'âge de début de l'obligation scolaire
Behrendt, Christian ULg

in Revue Belge de Droit Constitutionnel (2016), 2016

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See detailL’administration Obama, a t-elle (vraiment) navigué à vue sur la scène mondiale ?
Santander, Sébastian ULg

in Recherches internationales (2016), 106

Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous ... [more ▼]

Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous-entendu qu’il ne se laisserait pas enfermer dans des cadres idéologiques et qu’il privilégierait une approche « pragmatique » et « souple », et fait savoir qu’il n’engagerait plus les ÉU dans des opérations militaires de grande envergure. Ce discours d’une approche au cas par cas combiné à la politique du retrait militaire d’Irak et d’Afghanistan, et au fait que Obama a parfois été amené à adopter une attitude réactive pour répondre aux soubresauts de l’actualité internationale ont alimenté la perception dominante selon laquelle cette administration se désintéressait et se désengageait du monde, et déployait une politique étrangère marquée par l’indécision, l’improvisation et l’absence de vision à long terme. On ne peut omettre que cette administration a parfois du adapter et ajuster sa politique en fonction des événements internationaux. Faut-il pour autant conclure que sous Obama la première puissance mondiale a navigué à vue sur la scène internationale ? [less ▲]

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See detailMacro-economic factors influencing the architectural business model shift in the pharmaceutical industry
Dierks, Raphaela Marie Louisa ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg et al

in Expert Review of Pharmacoeconomics & Outcomes Research (2016), First online

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its ... [more ▼]

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its underlying business model. Despite significant articles in the press, there is little medical and economic evidence on the rationale driving the transformation from the traditional Research & Development (R&D) model to new alternative business models, such as Mergers & Acquisitions (M&A). The purpose of this review is to understand the macro-economic factors responsible for the revolution of the pharmaceutical business model, by understanding the needs, desires, new behavioral patterns, but also challenges within the industry. Considering these changes will be the key to possessing a competitive advantage over the market players. Areas covered: Existing literature on new macro-economic factors changing the pharmaceutical landscape has been reviewed to present a clear image of the current market environment. Expert commentary: Literature and media sources show that pharmaceutical companies are facing an architectural alteration in their business model, with more M&A deals and collaborations headlining the papers. Although Q1 2016 did show a major slowdown in M&A deals by volume since 2013 (with deal cancellations of Pfizer and Allergan, or the downfall of Valeant) pharmaceutical analysts remain confident that this shortfall was a consequence of the equity market volatility. It seems likely that the shift to an M&A model will become apparent during the remainder of 2016, with deal announcements such as Abbott Laboratories, AbbVie and Sanofi worth USD 45billion [1] showing the appetite of big pharma companies to shift from the fully vertical integrated business model to more horizontal business models. [less ▲]

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See detailFire Performance of Columns made of Normal and High Strength Concrete: A Comparative Analysis
Gernay, Thomas ULg

in Key Engineering Materials (2016), 711

The use of high strength concrete (HSC) in multi-story buildings has become increasingly popular. Selection of HSC over normal strength concrete (NSC) allows for reducing the dimensions of the columns ... [more ▼]

The use of high strength concrete (HSC) in multi-story buildings has become increasingly popular. Selection of HSC over normal strength concrete (NSC) allows for reducing the dimensions of the columns sections. However, this reduction has consequences on the structural performance in case of fire, as smaller cross sections lead to faster temperature increase in the section core. Besides, HSC experiences higher rates of strength loss with temperature and a higher susceptibility to spalling than NSC. The fire performance of a column can thus be affected by selecting HSC over NSC. This research performs a comparison of the fire performance of HSC and NSC columns, based on numerical simulations by finite element method. The thermal and structural analyses of the columns are conducted with the software SAFIR®. The variation of concrete strength with temperature for the different concrete classes is adopted from Eurocode. Different configurations are compared, including columns with the same load bearing capacity and columns with the same cross section. The relative loss of load bearing capacity during the fire is found to be more pronounced for HSC columns than for NSC columns. The impact on fire resistance rating is discussed. These results suggest that consideration of fire loading limits the opportunities for use of HSC, especially when the objective is to reduce the dimensions of the columns sections. [less ▲]

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See detailDu stilus à la plume ... du chapeau. Quelques réflexions sur la notion de style
Houbart, Claudine ULg

in Bruxelles Patrimoines (2016), (18),

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See detailL'EBM peut-elle encore enthousiasmer ?
Henrard, Gilles ULg

in Minerva: Tijdschrift Voor Evidence Based Medicine (2016)

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