References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 201 to 300 of 48464     1 2 3 4 5 6 7 8     Conditions de travail, stress et burnout des professionnels belges de radiothérapie: analyse comparative et exploration du rôle du travail émotionnelLaurent, Julie ; BRAGARD, Isabelle ; COUCKE, Philippe et alin Cancer Radiotherapie (in press)Detailed reference viewed: 60 (23 ULg) Compte rendu de l'ouvrage de Fr. Lissarrague, "La cité des satyres. Une anthropologie ludique (Athènes, VIe-Ve siècle avant J.-C.)"Veymiers, Richard in Revue de l'Histoire des Religions (in press)Detailed reference viewed: 9 (0 ULg) Practical management of Chronic Myeloid Leukemia in BelgiumBenghiat, FS.; Beguin, Yves ; Dessars, B. et alin Belgian Journal of Hematology (in press)Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]Detailed reference viewed: 48 (0 ULg) Dose-dependent effect of experimental Schmallenberg virus infection in sheepPoskin, A; Martinelle, Ludovic ; Mostin, L et alin Veterinary Journal (in press)Detailed reference viewed: 18 (5 ULg) Exploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for datingGuibert, Pierre; Urbanova, Petra; Blain, Sophie et alin Radiation Measurements (in press)Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]Detailed reference viewed: 28 (2 ULg) PLACE DE LA GERIATRIE DANS LA FILIERE DES SOINSPETERMANS, Jean in Revue Médicale de Liège (in press)Detailed reference viewed: 40 (17 ULg) DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial ThrombosisMusumeci, Lucia ; Kuijpers, Marijke; Gilio, Karen et alin Circulation (in press)Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet ... [more ▼]Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet activation is of importance for the development of improved therapies. Recently, protein tyrosine phosphatases (PTPs) have emerged as critical regulators of platelet function. Methods and Results This is the first report implicating the dual-specificity phosphatase 3 (DUSP3) in platelet signaling and thrombosis. This phosphatase is highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2 (CLEC-2). DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism, compared to wild-type mice, and showed severely impaired thrombus formation upon ferric chloride-induced carotid artery injury. Intriguingly, bleeding times were not altered in DUSP3-deficient mice. At the molecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphorylation of PLCγ2 and calcium fluxes. To investigate DUSP3 function in human platelets, a novel small-molecule inhibitor of DUSP3 was developed. This compound specifically inhibited collagen and CLEC-2-induced human platelet aggregation, thereby phenocopying the effect of DUSP3 deficiency in murine cells. Conclusions DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo. Inhibition of DUSP3 may prove therapeutic for arterial thrombosis. This is the first time a PTP, implicated in platelet signaling, has been targeted with a small-molecule drug. [less ▲]Detailed reference viewed: 27 (13 ULg) Spinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?Mancuso, Eva in Dissensus (in press), 6Detailed reference viewed: 95 (23 ULg) Island floras are not necessarily more species-poor than continental ones.Patiño, J.; Solymos, P.; Carine, M.A. et alin Journal of Biogeography (in press)Detailed reference viewed: 15 (0 ULg) Clinical sentinel surveillance of equine West Nile fever, SpainSaegerman, Claude ; Alba-Casals, A; Garcia-Bocanegra, I et alin Transboundary and Emerging Diseases (in press)Detailed reference viewed: 13 (3 ULg) Short communication: Novel method to predict body weight of primiparous dairy cows throughout the lactationVanrobays, Marie-Laure ; Vandenplas, Jérémie ; Hammami, Hedi et alin Journal of Dairy Science (in press)Body weight (BW) of dairy cows can be estimated using linear conformation traits (calculated BW; CBW), which are generally recorded only once during a lactation. However, predicted BW (PBW) throughout the ... [more ▼]Body weight (BW) of dairy cows can be estimated using linear conformation traits (calculated BW; CBW), which are generally recorded only once during a lactation. However, predicted BW (PBW) throughout the lactation would be useful, e.g., at milk-recording dates allowing feed-intake prediction for advisory purposes. Therefore, a 2-step approach was developed to obtain PBW for each milk-recording date. In the first step, a random-regression test-day model was used with CBW as observations to predict PBW. The second step consisted in changing means and (co)variances of prior distributions for the additive genetic random effects of the test-day model by using priors derived from results of the first step to predict again PBW. A total of 25,061 CBW from 24,919 primiparous Holstein cows were computed using equations from literature. Using CBW as observations, PBW was then predicted over the whole lactation for 232,436 dates corresponding to 207,375 milk-recording dates and 25,061 classification dates. Results showed that using both steps (the 2-step approach) provided more accurate predictions than using only the first step (the one-step approach). Based on the results of this preliminary study, BW of dairy cows could be predicted throughout the lactation using this procedure. These predictions could be useful in milk-recording systems to compute traits of interest (e.g., feed-intake prediction). The developed novel method is also flexible because actual direct measurements of BW can also be used together with CBW, the prediction model being able to accommodate different levels of accuracies of used BW phenotypes. [less ▲]Detailed reference viewed: 22 (6 ULg) Délinquance des adolescents et maturation pubertaire analysées au travers du timing pubertaire perçuGlowacz, Fabienne ; Bourguignon, Jean-Pierre in Annales Médico-Psychologiques (in press)The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between ... [more ▼]The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between pubertal development and the manifestation of internalized and externalized disorders. Two predominant hypothesis are used for explain influence of pubertal timing on problem behaviors : the maturational deviance theory and the stage termination (early timing) theory. The deviance theory claims that the borderline or abnormal pubertal timing, whether early or late, causes difficulties for adolescent adaptation. The early timing theory suggests that early pubertal timing and the consequent early physical maturation put adolescents at greater risk of adjustment problems because early pubertal maturation interferes with normal progression through the developmental tasks of adolescence. Our study is interested specifically in the links between delinquency during adolescence and pubertal maturation in a population of 141 boys aged between 12 and 18. We measured the pubertal variable starting from the perceived pubertal timing (PPT), which evaluates the teenagers' perception of their pubertal maturation, compared with that of their peers, to understand its impact on various dimensions of the functioning of teenagers: the self-perception (scale of Harter), aggressiveness (scale of Buss and Perry), association with peers and self-reported delinquency (attacks on property and individuals). We began with univariate analyses in order to determine the variables associated with early or late pubertal timing through comparison of scores obtained in those subjects with reference to average maturers. Subsequently, multivariate analyses were used in an attempt to sort out which among the studied factors could be predictor or a determinant of delinquency in relation to pubertal timing. Therefore, stepwise multiple regression analysis was performed. Statistical analyses were run with the SAS software, version 9.1.Our results support the thesis of precocity, the teenagers with an advanced PPT present scores of delinquency and aggressiveness significantly higher than teenagers with a standard PPT. However, the sub-group of teenagers with delayed PPT present raw scores of self-revealed delinquency which are higher than those of teenagers with a standard PPT. These teenagers can be characterized by a significantly higher hostility than the teenagers with a standard PPT. This cognitive dimension of aggressiveness, as evaluated by Buss and Perry, characterizes the functioning of the teenagers with the delayed PPT, who also present poorer self-esteem and dissatisfaction with their physical appearance. On the basis of this assessment, an analysis of multiple regression within each type of PPT aimed at identifying the variables likely to explain the delinquency of teenagers according to their PPT. The results show that the physical factor of aggressiveness is common to the three types of PPT. It is associated with the affiliation with delinquent peers for those teenagers with advanced and normal PPT, whereas for those teenagers with delayed PPT, it interacts with the factor of hostility, which is specific to them. Association with delinquent peers recognized as a major risk factor and predictive for the self-revealed delinquency of teenagers in general does not intervene for these boys who perceive their pubertal development late, compared to the others. The delinquency of teenagers with a delayed PPT cannot be explained by the factors that are considered in the general population, their social functioning and the socialization of these teenagers with delayed puberty is different from that of the other teenagers, as is their implication in delinquency, which is not explained by a kind of socialization with delinquent peers. These results confirm the importance of integrating the puberty variable into research on delinquency, but also at the level of intervention. [less ▲]Detailed reference viewed: 8 (0 ULg) Les ambiguïtés de l’anthropomorphisme : de la divinité agissante à sa statue dans la céramique grecqueCollard, Hélène in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce ... [more ▼]L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce, la figuration anthropomorphe des dieux est largement majoritaire. Toutefois, en se tournant vers un support particulier, le vase peint, et un type de représentation particulier, la statue divine, on montrera ici que l’anthropomorphisme a pu amener une certaine ambiguïté. Dans la céramique, les représentations de statues fonctionnent sur plusieurs modes, selon la chronologie. C’est ce que l’on propose d’analyser, en examinant un groupe de vases décorés d’un thème semblable et sur lesquels une divinité est représentée, mais soit sous la forme d’une figure « vivante », soit d’une statue plus ou moins bien caractérisée. Cette étude permettra d’aborder les concepts de « fixité » et de « mouvement » de/dans l’image, mais aussi d’explorer quelques pistes de réflexions sur l’image divine et, plus largement, sur les modes de représentation du divin en Grèce ancienne. [less ▲]Detailed reference viewed: 45 (1 ULg) PLACE DE LA GERIATRIE DANS LA FILIERE DES SOINSPETERMANS, Jean in Revue Médicale de Liège (in press)Detailed reference viewed: 40 (17 ULg) Personnes âgées et troubles de la déglutition : approche pluridisciplinaireALLEPAERTS, Sophie ; DELCOURT, Sandrine ; PETERMANS, Jean in Revue Médicale de Liège (in press)Detailed reference viewed: 117 (18 ULg) Retour au sport après plastie du ligament croisé antérieur : critères utilisés dans les cubs professionnels de footballDelvaux, François ; Rochcongar, P; Bruyère, Olivier et alin Science et Sports (in press)Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament ... [more ▼]Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament croisé antérieur chez un footballeur. Matériels et méthodes Trente-sept médecins responsables de clubs professionnels de football français et belges (Ligue 1, n = 15 ; Ligue 2, n = 14 ; Division 1 belge, n = 8) ont rempli un questionnaire à choix multiple concernant : (1) les critères utilisés afin de déterminer si un joueur est apte à reprendre la compétition après plastie du ligament croisé antérieur ; (2) l’importance relative de chacun de ces critères ; (3) le rôle éventuel d’intervenants spécifiques (kinésithérapeute…) dans cette décision. Résultats Plus de 80 % des médecins interrogés ont déclaré utiliser au moins huit critères (sur 17 proposés) afin d’évaluer la capacité d’un footballeur à reprendre la compétition après plastie du ligament croisé antérieur. Les trois critères considérés comme les plus déterminants étaient, par ordre d’importance : la stabilité dynamique du genou lors d’un exercice spécifique au football, la force musculaire et la récupération complète ou quasi complète d’amplitudes articulaires de flexion et d’extension de genou. Pour certains de ces critères (notamment la force musculaire), nous constatons cependant un manque de consensus sur les modalités pratiques d’évaluation, sur les paramètres ainsi que sur les valeurs-limites tolérées afin de garantir un retour sur terrain sécurisé. La prise en compte de l’avis du kinésithérapeute et du préparateur physique par une très nette majorité de médecins souligne l’importance d’un travail pluridisciplinaire. Conclusion L’utilisation de différents critères objectifs afin d’autoriser le retour compétitif après plastie du ligament croisé antérieur semble être une réalité dans le football professionnel. Des études supplémentaires devraient cependant contribuer à préciser les modalités des épreuves ainsi que des valeurs-seuils. ________________________________________ Summary Purpose To analyze how sport physicians decide, in their daily practice, when a professional soccer player with a reconstructed anterior cruciate ligament is able to get back to competitive activities. Materials and methods Thirty-seven physicians for professional French and Belgian soccer teams filled in a specific questionnaire dedicated to: (1) return-to-play criteria after anterior cruciate reconstruction; (2) the importance they assigned to each of these criteria in the return-to-play decision; (3) the potential role of professionals, such as physiotherapists or physical coaches in this decision. Results More than 80% of the respondents declared to use at least eight criteria in order to assess the player's ability to return to competitive soccer after anterior cruciate ligament reconstruction. The most important ones were (in order of importance): dynamic knee stability during a specific soccer exercise, muscle strength performance and normalization of knee flexion and extension ranges of motion. For most of these criteria (notably muscle strength), there was a lack of consensus about the choice of assessment parameters and the limit values allowing physicians to authorize or forbid the return-to-competition. A large majority of participants stated to take into consideration advices from physiotherapists or physical coaches for the return-to-play decision. Conclusion Sport physicians of professional soccer teams use relevant criteria to assess players’ ability to return to full sport after anterior cruciate ligament reconstruction. Further studies are required to determine the choice of assessment parameters and the limit values to assist physicians in return-to-play decisions. [less ▲]Detailed reference viewed: 24 (3 ULg) Trunk muscle profile in elite tennis players with and without low back painGROSDENT, Stéphanie ; Demoulin, Christophe ; Souchet, Matthieu et alin Journal of Sports Medicine & Physical Fitness (in press)Detailed reference viewed: 70 (21 ULg) L'idéologie de la Nieuw‐Vlaamse AlliantieJamin, Jérôme in Revue européenne de géopolitique Outre-Terre (in press)Detailed reference viewed: 34 (8 ULg) Le point sur l’évaluation de la force des muscles respiratoiresKellens, Isabelle ; Crielaard, Jean-Michel in Revue Médicale de Liège (in press)The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]Detailed reference viewed: 149 (39 ULg) Les Fumistes wallons, un collectif en figurationSaint-Amand, Denis in Textyles : Revue des Lettres Belges de Langue Française (in press)Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert ... [more ▼]Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert Mockel). On y montre comment, en tant qu’entrée en littérature, le texte de Mockel se donne à voir comme un positionnement singulier vis-à-vis de l’espace littéraire, dont l’auteur aborde d’emblée le fonctionnement en le raillant. [less ▲]Detailed reference viewed: 26 (3 ULg) Bayesian inference for transportation origin–destination matrices: the Poisson–inverse Gaussian and other Poisson mixturesPerrakis, Konstantinos; Karlis, Dimitris; Cools, Mario et alin Journal of the Royal Statistical Society. Series A Statistics in Society (in press)Transportation origin–destination analysis is investigated through the use of Poisson mixtures by introducing covariate-based models which incorporate different transport modelling phases and also allow ... [more ▼]Transportation origin–destination analysis is investigated through the use of Poisson mixtures by introducing covariate-based models which incorporate different transport modelling phases and also allow for direct probabilistic inference on link traffic based on Bayesian predictions. Emphasis is placed on the Poisson–inverse Gaussian model as an alternative to the commonly used Poisson–gamma and Poisson–log-normal models. We present a first full Bayesian formulation and demonstrate that the Poisson–inverse Gaussian model is particularly suited for origin–destination analysis because of its desirable marginal and hierarchical properties. In addition, the integrated nested Laplace approximation is considered as an alternative to Markov chain Monte Carlo sampling and the two methodologies are compared under specific modelling assumptions. The case-study is based on 2001 Belgian census data and focuses on a large, sparsely distributed origin–destination matrix containing trip information for 308 Flemish municipalities. [less ▲]Detailed reference viewed: 22 (6 ULg) Place de la vitamine D native en dialyseDELANAYE, Pierre ; BOUQUEGNEAU, Antoine ; KRZESINSKI, Jean-Marie et alin Néphrologie & Thérapeutique (in press)Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first ... [more ▼]Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first hydroxylation in the liver, and a second one in the kidney. Next to its action on bone metabolism, vitamin D also possesses pleiotropic actions on cardiovascular, immune and neurological systems as well as antineoplastic activities. End-stage renal disease (ESRD) is also associated with a decrease in vitamin D activity by mechanisms including the increase of plasma phosphate concentration, secretion of FGF- 23 and decrease in 1a-hydroxylase activity. The prevalence of 25 hydroxy-vitamin D deficiency depends on the chosen cut-off value to define this lack. Currently it is well established that a patient has to be substituted when 25 hydroxy-vitamin D level is under 30 ng/mL. The use and monitoring of 1.25 hydroxy-vitamin D is still not recommended in routine practice. The goals of vitamin D treatment in case of ESRD are to substitute the deficiency and to prevent or treat hyperparathyroidism. Interest of native vitamin D in first intention is now well demonstrated. This review article describes the vitamin D metabolism and physiology and also the treatment for vitamin D deficiency in ESRD population. [less ▲]Detailed reference viewed: 9 (3 ULg) When women support the patriarchal family. The dynamics of marriage in a Gécamines mining camp (Katanga province, DR Congo)Rubbers, Benjamin in Journal of Historical Sociology (in press)Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long ... [more ▼]Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long characterized by paternalism. The results of this research suggest that, though men and women living in this mining community talk about their spousal relationships by invoking the ideal of Christian marriage promoted during the colonial period, in practice such relationships faced important changes following Congolese independence in 1960. The nationalization and subsequent dramatic decline of Gécamines caused changes which directly affected three central dimensions of the colonial family model, namely monogamy, the ideal of domesticity, and male authority. If men and women continue to reference this model, it is because, in times of growing poverty, it allows spouses to remind one other of their respective duties as docile housewives and responsible husbands, and to command respect as virtuous Christian families in the local community. [less ▲]Detailed reference viewed: 22 (3 ULg) About the Uniform Hölder Continuity of Generalized Riemann FunctionBastin, Françoise ; Nicolay, Samuel ; Simons, Laurent in Mediterranean Journal of Mathematics (in press)In this paper, we study the uniform H\"{o}lder continuity of the generalized Riemann function~$R_{\alpha,\beta}$ (with $\alpha>1$ and $\beta>0$) defined by $R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac ... [more ▼]In this paper, we study the uniform H\"{o}lder continuity of the generalized Riemann function~R_{\alpha,\beta} (with \alpha>1 and \beta>0) defined by \[ R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac{\sin(\pi n^\beta x)}{n^\alpha},\quad x\in\mathbb{R},$ using its continuous wavelet transform. In particular, we show that the exponent we find is optimal. We also analyse the behaviour of~$R_{\alpha,\beta}$ as $\beta$ tends to infinity. [less ▲]Detailed reference viewed: 16 (1 ULg) A mysterious giant ichthyosaur from the lowermost Jurassic of WalesMartin, Jeremy E; Vincent, Peggy; Suan, Guillaume et alin Acta Palaeontologica Polonica (in press)Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic ... [more ▼]Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic. Timing and causes of this demise and the subsequent rapid radiation of the diverse, but less disparate, parvipelvian ichthyosaurs are still unknown, notably because of inadequate sampling in strata of latest Triassic age. Here, we describe an exceptionally large radius from Lower Jurassic deposits at Penarth near Cardiff, South Wales (UK) the morphology of which places it within the giant Triassic shastasaurids. A tentative total body size estimate, based on a regression analysis of various complete ichthyosaur skeletons, yields a value of 12-15 m. The specimen is substantially younger than any previously reported last known occurrences of shastasaurids and implies a Lazarus range in the lowermost Jurassic for this ichthyosaur morphotype. [less ▲]Detailed reference viewed: 38 (3 ULg) Les états spatio-temporels d'existence et de présenceHallot, Pierre ; Stewart, Kathleen; Billen, Roland in Revue Internationale de Géomatique = International Journal of Geomatics and Spatial Analysis (in press)This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an ... [more ▼]This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an analysis of the spatiotemporal states of existence and presence for a geographical object. Then, we combine the spatiotemporal states to define a comprehensive set of life and motion configuration. The proposed model serves as formal basis to perform spatiotemporal queries by retrieving selected patterns in the life and motion configurations. The research is applied to the organization of a scientific conference, in doing so we are able to define the relationships that exist between an event located in space and time and mobiles objects evolving within the space, i.e. the conference participants. [less ▲]Detailed reference viewed: 28 (2 ULg) Internet facilite-t-il chez les étudiants du supérieur un apprentissage de plus en plus autorégulé ?Poumay, Marianne in Revue Internationale des Technologies en Pédagogie Universitaire (in press)The article specifies the meaning of “self-regulated learning”, then illustrates, first in course then in a program, a few practices using Internet as a support for learning. It underlines in those ... [more ▼]The article specifies the meaning of “self-regulated learning”, then illustrates, first in course then in a program, a few practices using Internet as a support for learning. It underlines in those practices the growing importance of self-regulated learning. It advocates for supporting, mentoring the students in their development of that self-regulation, often implicit and considered granted in the Internet based course environments. [less ▲]Detailed reference viewed: 51 (3 ULg) Osteoporosis in patients taking selective serotonin reuptake inhibitors: a focus on fracture outcomeBruyère, Olivier ; Reginster, Jean-Yves in Endocrine (in press)Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of ... [more ▼]Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of depressive symptoms among older adults because of their presumed favorable adverse effect profile. However, they could have deleterious effects on the bone. Evidence from longitudinal, crosssectional, and prospective cohort studies suggests that the use of antidepressants at therapeutic doses is associated with decreased bone mineral density and increased fracture risk. The association between SSRIs use and fracture risk could potentially differ depending on dose, exposure duration, time of exposure, age, or sex. However, the risk of fracture declined rapidly after discontinuation of use of SSRIs. The evidence now seems sufficient to consider adding SSRIs to the list of medications that contribute to osteoporosis. In practice, assessment of risk factor for osteoporosis or fractures could be made taking into account age, gender, duration, and severity of depression, length of SSRI treatments, and other concurrent risk factors. [less ▲]Detailed reference viewed: 27 (13 ULg) Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countriesCastano, Argelia; Cutanda, Francisco; Esteban, Marta et alin Environmental Research (in press)The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential ... [more ▼]The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-​levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-​child pairs from 17 European countries using a strictly harmonized protocol for mercury anal. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster anal. of consumption habits of the mother-​child pairs, the DEMOCOPHES cohort can be classified into two branches of approx. similar size: one with high fish consumption (H) and another with low consumption (L)​. All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-​child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concn. between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-​child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish contribute significantly to the mercury levels in hair. We conclude that addnl. studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster anal. also showed that 95​% of mothers who consume once per wk fish only, and no other marine products, have mercury levels 0.55 μg​/g. Thus, the 95th percentile of the distribution in this group is only around half the US-​EPA recommended threshold of 1 μg​/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an addnl. dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements. [less ▲]Detailed reference viewed: 40 (8 ULg) Diversity of germination strategies and dormancy of graminoid and forb species of campo rupestre grasslandsLe Stradic, Soizig ; Silveira, Fernando A. O.; Buisson, Elise et alin Austral Ecology (in press)Detailed reference viewed: 9 (0 ULg) Dietary early-life exposure to contaminated eels does not impair spatial cognitive performances in adult offspring mice as assessed in the Y-maze and the Morris water mazeDridi, ImenI; Leroy, Delphine; Guignard, Cedric et alin Nutrition Research (in press)Many environmental contaminants are introduced via the diet and may act as neurotoxins and endocrine disrupters, especially influencing growing organisms in early life. The purpose of this study was to ... [more ▼]Many environmental contaminants are introduced via the diet and may act as neurotoxins and endocrine disrupters, especially influencing growing organisms in early life. The purpose of this study was to examine whether dietary exposure of dams to fish naturally contaminated with xenobiotics, especially with polychlorinated biphenyls (PCBs) and heavy metals (e.g. mercury and lead), resulted in cognitive function deficits in adult offspring mice. Daily, four groups of dams (n = 10/group) ingested standard diet plus paste with/without eels, during gestation and lactation, from gestational day (GD) six until post natal day (PND) 21 (weaning). Dams orally ingested a standardized amount of eel (0.8 mgkg-1 d-1) containing the six non-dioxin-like (NDL) PCBs (σ6 NDL-PCBs: 28, 52, 101, 138, 153, and 180) at 0, 85, 216, and 400 ngkg-1 d-1. Results showed that early-life exposure to contaminated eels did not (compared to non-exposed controls) impair immediate working memory in the Y-maze in the offspring assessed at PND 38. Furthermore, it did not significantly impact spatial learning and retention memory as measured in the Morris water maze in adult offspring mice (PND 120-123). Our results suggest that perinatal exposure to contaminated eels does not affect spatial cognitive performances, as assessed by the Y-maze and Morris water maze at adult age. Adverse effects of xenobiotics reported earlier might be camouflaged by beneficial eel constituents, such as n-3 fatty acids. However, additional studies are needed to differentiate between potential positive and negative effects following consumption of food items both rich in nutrients and contaminants. © 2014 Elsevier Inc. [less ▲]Detailed reference viewed: 17 (4 ULg) Out of Himalaya: the impact of past Asian environmental changes on the evolutionary and biogeographical history of Dipodoidea (Rodentia)Pisano, Julie ; Condamine, Fabien L.; Lebedev, Vladimir et alin Journal of Biogeography (in press)Detailed reference viewed: 4 (0 ULg) La sécurité affective chez l'enfant en milieu résidentiel : Des soins du corps au bien être émotionnelAprile, Pauline ; Englebert, Jérôme ; Gauthier, Jean-Marie in Evolution Psychiatrique (in press)Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to ... [more ▼]Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to show that sufficient affective security can be achieved even in children institutionalized with major attachment difficulties. Method - We will first examine the original meaning of the concept by a theoretical review of its evolution over the years in the literature. Then, we will consider various questions concerning the legitimacy of institutionalization in link with affective security through a case analysis illustrating the issue. We will finally end by mentioning the main practical implications about the optimization of affective security in children institutionalized. Results - It is foremost by the predictable and expected daily acts posed by the professional caregivers in institution that the child may find sufficient affective security, generating emotional well-being and ultimately, an overall adequate development. Discussion – Children early separated from their family home to be placed in residential institution most often suffer from serious difficulties in terms of attachment to others. In this context, the institution has to deal with a specifically challenge: that is, to help the child to (re-)find sufficient internal security to allow him to grow on solid foundations. The institutional life which replaces family life primarily consists of an organizational structure that seeks to make child life as predictable as possible so that it has the necessary daily benchmarks to evolve adequately. Conclusion – In the everyday life in institution, the professionals struggling with children’s attachment disorders constantly try to achieve a right emotional-body balance through their psycho-educational practices with the child deprived of secure attachment strategies. [less ▲]Detailed reference viewed: 125 (12 ULg) Phénoménologie autrichienne: le programme de BrentanoDewalque, Arnaud in Austriaca (in press)It is usual to think of the spectacular development of the Brentano School in Austria as being tied to the rise of a specific research program, which is sometimes dubbed “Austrian phenomenology”. I ... [more ▼]It is usual to think of the spectacular development of the Brentano School in Austria as being tied to the rise of a specific research program, which is sometimes dubbed “Austrian phenomenology”. I discuss here some evidences for the existence of such a program. In the discussion, I highlight two claims which I take to be constitutive of the Brentanian phenomenology. The first one is the epistemological claim according to which our concepts all have an empirical origin, which has to be located in the experience we have of our own mental states. The second one is the methodological claim according to which describing a mental phenomenon P is nothing but analysing P, where “analysing P” simply means “distinctly perceiving all the constituents of P”. Although a deeper insight in those two claims would require considerable further investigations, I suggest they should be part of the picture when it comes to adjudicating on the specificity of the Brentanian program. [less ▲]Detailed reference viewed: 44 (4 ULg) Vitamin D status after a high dose of cholecalciferol in healthy and burn subjectsROUSSEAU, Anne-Françoise ; DAMAS, Pierre ; LEDOUX, Didier et alin Burns : Journal of the International Society for Burn Injuries (in press)Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a ... [more ▼]Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a cholecalciferol (VD3) bolus on VD status in adult burn patients (Group B, GB) after admission, compared to healthy subjects (Group H, GH). Methods: Both groups received an oral dose of 100,000 IU VD3. Blood samples were collected before (D0) and 7 days (D7) after bolus to measure 250H-D, 1,25(OH)2-D, parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). Albumin (ALB) and VD binding protein (DBP) were measured and used to calculate free 25OH-D level. Data were expressed as median (min–max) or proportions. Results: A total of 49 subjects were included: 29 in GH and 20 in GB. At D0, prevalence of VD deficiency was higher in GB: 25OH-D was 21.5 (10.1–46.3) ng/ml in GH vs 11 (1.8–31.4) ng/ml in GB. DBP and ALB were lower in GB. At D7, DBP was stable in both groups while ALB decreased in GB. 25OH-D increased by 66.6 (13.5–260.3)% in GH. In GB, changes in 25OH-D extended from 36.7% to 333.3% with a median increase of 33.1%. Similar changes were observed in each group for free 25OH-D. High FGF23 levels were observed in GB. Conclusions: This study highlighted the differences in VD status and in response to a high dose VD3 in burn patients when compared to healthy patients. Pitfalls in VD status assessment are numerous during acute burn care: 25OH-D measurement needs cautious interpretation and interest of free 25OH-D is still questionable. They should not prevent burn patients to receive VD supplements during acute care. Higher doses than general recommendations should probably be considered. [less ▲]Detailed reference viewed: 5 (2 ULg) Spinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?Mancuso, Eva in Dissensus (in press), 6Detailed reference viewed: 95 (23 ULg) Cost-effectiveness of vitamin D and calcium supplementation in the treatment of elderly women and men with osteoporosis.Hiligsmann, Mickaël ; Ben Sedrine, Wafa; Bruyère, Olivier et alin European journal of public health (in press)BACKGROUND: The supplementation with vitamin D and calcium has been recommended for elderly, specifically those with increased risk of fractures older than 65 years. This study aims to assess the cost ... [more ▼]BACKGROUND: The supplementation with vitamin D and calcium has been recommended for elderly, specifically those with increased risk of fractures older than 65 years. This study aims to assess the cost-effectiveness of vitamin D and calcium supplementation in elderly women and men with osteoporosis and therefore to assess if this recommendation is justified in terms of cost-effectiveness. METHODS: A validated model for economic evaluations in osteoporosis was used to estimate the cost per quality-adjusted life-year (QALY) gained of vitamin D/calcium supplementation compared with no treatment. The model was populated with cost and epidemiological data from a Belgian health-care perspective. Analyses were conducted in women and men with a diagnosis of osteoporosis (i.e. bone mineral density T-score