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See detailPractical management of Chronic Myeloid Leukemia in Belgium
Benghiat, FS.; Beguin, Yves ULg; Dessars, B. et al

in Belgian Journal of Hematology (in press)

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]

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See detailDose-dependent effect of experimental Schmallenberg virus infection in sheep
Poskin, A; Martinelle, Ludovic ULg; Mostin, L et al

in Veterinary Journal (in press)

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See detailExploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for dating
Guibert, Pierre; Urbanova, Petra; Blain, Sophie ULg et al

in Radiation Measurements (in press)

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]

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See detailPLACE DE LA GERIATRIE DANS LA FILIERE DES SOINS
PETERMANS, Jean ULg

in Revue Médicale de Liège (in press)

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See detailDUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis
Musumeci, Lucia ULg; Kuijpers, Marijke; Gilio, Karen et al

in Circulation (in press)

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet ... [more ▼]

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet activation is of importance for the development of improved therapies. Recently, protein tyrosine phosphatases (PTPs) have emerged as critical regulators of platelet function. Methods and Results This is the first report implicating the dual-specificity phosphatase 3 (DUSP3) in platelet signaling and thrombosis. This phosphatase is highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2 (CLEC-2). DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism, compared to wild-type mice, and showed severely impaired thrombus formation upon ferric chloride-induced carotid artery injury. Intriguingly, bleeding times were not altered in DUSP3-deficient mice. At the molecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphorylation of PLCγ2 and calcium fluxes. To investigate DUSP3 function in human platelets, a novel small-molecule inhibitor of DUSP3 was developed. This compound specifically inhibited collagen and CLEC-2-induced human platelet aggregation, thereby phenocopying the effect of DUSP3 deficiency in murine cells. Conclusions DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo. Inhibition of DUSP3 may prove therapeutic for arterial thrombosis. This is the first time a PTP, implicated in platelet signaling, has been targeted with a small-molecule drug. [less ▲]

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailIsland floras are not necessarily more species-poor than continental ones.
Patiño, J.; Solymos, P.; Carine, M.A. et al

in Journal of Biogeography (in press)

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See detailClinical sentinel surveillance of equine West Nile fever, Spain
Saegerman, Claude ULg; Alba-Casals, A; Garcia-Bocanegra, I et al

in Transboundary and Emerging Diseases (in press)

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See detailShort communication: Novel method to predict body weight of primiparous dairy cows throughout the lactation
Vanrobays, Marie-Laure ULg; Vandenplas, Jérémie ULg; Hammami, Hedi ULg et al

in Journal of Dairy Science (in press)

Body weight (BW) of dairy cows can be estimated using linear conformation traits (calculated BW; CBW), which are generally recorded only once during a lactation. However, predicted BW (PBW) throughout the ... [more ▼]

Body weight (BW) of dairy cows can be estimated using linear conformation traits (calculated BW; CBW), which are generally recorded only once during a lactation. However, predicted BW (PBW) throughout the lactation would be useful, e.g., at milk-recording dates allowing feed-intake prediction for advisory purposes. Therefore, a 2-step approach was developed to obtain PBW for each milk-recording date. In the first step, a random-regression test-day model was used with CBW as observations to predict PBW. The second step consisted in changing means and (co)variances of prior distributions for the additive genetic random effects of the test-day model by using priors derived from results of the first step to predict again PBW. A total of 25,061 CBW from 24,919 primiparous Holstein cows were computed using equations from literature. Using CBW as observations, PBW was then predicted over the whole lactation for 232,436 dates corresponding to 207,375 milk-recording dates and 25,061 classification dates. Results showed that using both steps (the 2-step approach) provided more accurate predictions than using only the first step (the one-step approach). Based on the results of this preliminary study, BW of dairy cows could be predicted throughout the lactation using this procedure. These predictions could be useful in milk-recording systems to compute traits of interest (e.g., feed-intake prediction). The developed novel method is also flexible because actual direct measurements of BW can also be used together with CBW, the prediction model being able to accommodate different levels of accuracies of used BW phenotypes. [less ▲]

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See detailDélinquance des adolescents et maturation pubertaire analysées au travers du timing pubertaire perçu
Glowacz, Fabienne ULg; Bourguignon, Jean-Pierre ULg

in Annales Médico-Psychologiques (in press)

The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between ... [more ▼]

The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between pubertal development and the manifestation of internalized and externalized disorders. Two predominant hypothesis are used for explain influence of pubertal timing on problem behaviors : the maturational deviance theory and the stage termination (early timing) theory. The deviance theory claims that the borderline or abnormal pubertal timing, whether early or late, causes difficulties for adolescent adaptation. The early timing theory suggests that early pubertal timing and the consequent early physical maturation put adolescents at greater risk of adjustment problems because early pubertal maturation interferes with normal progression through the developmental tasks of adolescence. Our study is interested specifically in the links between delinquency during adolescence and pubertal maturation in a population of 141 boys aged between 12 and 18. We measured the pubertal variable starting from the perceived pubertal timing (PPT), which evaluates the teenagers' perception of their pubertal maturation, compared with that of their peers, to understand its impact on various dimensions of the functioning of teenagers: the self-perception (scale of Harter), aggressiveness (scale of Buss and Perry), association with peers and self-reported delinquency (attacks on property and individuals). We began with univariate analyses in order to determine the variables associated with early or late pubertal timing through comparison of scores obtained in those subjects with reference to average maturers. Subsequently, multivariate analyses were used in an attempt to sort out which among the studied factors could be predictor or a determinant of delinquency in relation to pubertal timing. Therefore, stepwise multiple regression analysis was performed. Statistical analyses were run with the SAS software, version 9.1.Our results support the thesis of precocity, the teenagers with an advanced PPT present scores of delinquency and aggressiveness significantly higher than teenagers with a standard PPT. However, the sub-group of teenagers with delayed PPT present raw scores of self-revealed delinquency which are higher than those of teenagers with a standard PPT. These teenagers can be characterized by a significantly higher hostility than the teenagers with a standard PPT. This cognitive dimension of aggressiveness, as evaluated by Buss and Perry, characterizes the functioning of the teenagers with the delayed PPT, who also present poorer self-esteem and dissatisfaction with their physical appearance. On the basis of this assessment, an analysis of multiple regression within each type of PPT aimed at identifying the variables likely to explain the delinquency of teenagers according to their PPT. The results show that the physical factor of aggressiveness is common to the three types of PPT. It is associated with the affiliation with delinquent peers for those teenagers with advanced and normal PPT, whereas for those teenagers with delayed PPT, it interacts with the factor of hostility, which is specific to them. Association with delinquent peers recognized as a major risk factor and predictive for the self-revealed delinquency of teenagers in general does not intervene for these boys who perceive their pubertal development late, compared to the others. The delinquency of teenagers with a delayed PPT cannot be explained by the factors that are considered in the general population, their social functioning and the socialization of these teenagers with delayed puberty is different from that of the other teenagers, as is their implication in delinquency, which is not explained by a kind of socialization with delinquent peers. These results confirm the importance of integrating the puberty variable into research on delinquency, but also at the level of intervention. [less ▲]

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See detailLes ambiguïtés de l’anthropomorphisme : de la divinité agissante à sa statue dans la céramique grecque
Collard, Hélène ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce ... [more ▼]

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce, la figuration anthropomorphe des dieux est largement majoritaire. Toutefois, en se tournant vers un support particulier, le vase peint, et un type de représentation particulier, la statue divine, on montrera ici que l’anthropomorphisme a pu amener une certaine ambiguïté. Dans la céramique, les représentations de statues fonctionnent sur plusieurs modes, selon la chronologie. C’est ce que l’on propose d’analyser, en examinant un groupe de vases décorés d’un thème semblable et sur lesquels une divinité est représentée, mais soit sous la forme d’une figure « vivante », soit d’une statue plus ou moins bien caractérisée. Cette étude permettra d’aborder les concepts de « fixité » et de « mouvement » de/dans l’image, mais aussi d’explorer quelques pistes de réflexions sur l’image divine et, plus largement, sur les modes de représentation du divin en Grèce ancienne. [less ▲]

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See detailPLACE DE LA GERIATRIE DANS LA FILIERE DES SOINS
PETERMANS, Jean ULg

in Revue Médicale de Liège (in press)

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See detailRetour au sport après plastie du ligament croisé antérieur : critères utilisés dans les cubs professionnels de football
Delvaux, François ULg; Rochcongar, P; Bruyère, Olivier ULg et al

in Science et Sports (in press)

Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament ... [more ▼]

Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament croisé antérieur chez un footballeur. Matériels et méthodes Trente-sept médecins responsables de clubs professionnels de football français et belges (Ligue 1, n = 15 ; Ligue 2, n = 14 ; Division 1 belge, n = 8) ont rempli un questionnaire à choix multiple concernant : (1) les critères utilisés afin de déterminer si un joueur est apte à reprendre la compétition après plastie du ligament croisé antérieur ; (2) l’importance relative de chacun de ces critères ; (3) le rôle éventuel d’intervenants spécifiques (kinésithérapeute…) dans cette décision. Résultats Plus de 80 % des médecins interrogés ont déclaré utiliser au moins huit critères (sur 17 proposés) afin d’évaluer la capacité d’un footballeur à reprendre la compétition après plastie du ligament croisé antérieur. Les trois critères considérés comme les plus déterminants étaient, par ordre d’importance : la stabilité dynamique du genou lors d’un exercice spécifique au football, la force musculaire et la récupération complète ou quasi complète d’amplitudes articulaires de flexion et d’extension de genou. Pour certains de ces critères (notamment la force musculaire), nous constatons cependant un manque de consensus sur les modalités pratiques d’évaluation, sur les paramètres ainsi que sur les valeurs-limites tolérées afin de garantir un retour sur terrain sécurisé. La prise en compte de l’avis du kinésithérapeute et du préparateur physique par une très nette majorité de médecins souligne l’importance d’un travail pluridisciplinaire. Conclusion L’utilisation de différents critères objectifs afin d’autoriser le retour compétitif après plastie du ligament croisé antérieur semble être une réalité dans le football professionnel. Des études supplémentaires devraient cependant contribuer à préciser les modalités des épreuves ainsi que des valeurs-seuils. ________________________________________ Summary Purpose To analyze how sport physicians decide, in their daily practice, when a professional soccer player with a reconstructed anterior cruciate ligament is able to get back to competitive activities. Materials and methods Thirty-seven physicians for professional French and Belgian soccer teams filled in a specific questionnaire dedicated to: (1) return-to-play criteria after anterior cruciate reconstruction; (2) the importance they assigned to each of these criteria in the return-to-play decision; (3) the potential role of professionals, such as physiotherapists or physical coaches in this decision. Results More than 80% of the respondents declared to use at least eight criteria in order to assess the player's ability to return to competitive soccer after anterior cruciate ligament reconstruction. The most important ones were (in order of importance): dynamic knee stability during a specific soccer exercise, muscle strength performance and normalization of knee flexion and extension ranges of motion. For most of these criteria (notably muscle strength), there was a lack of consensus about the choice of assessment parameters and the limit values allowing physicians to authorize or forbid the return-to-competition. A large majority of participants stated to take into consideration advices from physiotherapists or physical coaches for the return-to-play decision. Conclusion Sport physicians of professional soccer teams use relevant criteria to assess players’ ability to return to full sport after anterior cruciate ligament reconstruction. Further studies are required to determine the choice of assessment parameters and the limit values to assist physicians in return-to-play decisions. [less ▲]

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See detailTrunk muscle profile in elite tennis players with and without low back pain
GROSDENT, Stéphanie ULg; Demoulin, Christophe ULg; Souchet, Matthieu et al

in Journal of Sports Medicine & Physical Fitness (in press)

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See detailL'idéologie de la Nieuw‐Vlaamse Alliantie
Jamin, Jérôme ULg

in Revue européenne de géopolitique Outre-Terre (in press)

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See detailLe point sur l’évaluation de la force des muscles respiratoires
Kellens, Isabelle ULg; Crielaard, Jean-Michel ULg

in Revue Médicale de Liège (in press)

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]

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See detailLes Fumistes wallons, un collectif en figuration
Saint-Amand, Denis ULg

in Textyles : Revue des Lettres Belges de Langue Française (in press)

Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert ... [more ▼]

Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert Mockel). On y montre comment, en tant qu’entrée en littérature, le texte de Mockel se donne à voir comme un positionnement singulier vis-à-vis de l’espace littéraire, dont l’auteur aborde d’emblée le fonctionnement en le raillant. [less ▲]

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See detailBayesian inference for transportation origin–destination matrices: the Poisson–inverse Gaussian and other Poisson mixtures
Perrakis, Konstantinos; Karlis, Dimitris; Cools, Mario ULg et al

in Journal of the Royal Statistical Society. Series A Statistics in Society (in press)

Transportation origin–destination analysis is investigated through the use of Poisson mixtures by introducing covariate-based models which incorporate different transport modelling phases and also allow ... [more ▼]

Transportation origin–destination analysis is investigated through the use of Poisson mixtures by introducing covariate-based models which incorporate different transport modelling phases and also allow for direct probabilistic inference on link traffic based on Bayesian predictions. Emphasis is placed on the Poisson–inverse Gaussian model as an alternative to the commonly used Poisson–gamma and Poisson–log-normal models. We present a first full Bayesian formulation and demonstrate that the Poisson–inverse Gaussian model is particularly suited for origin–destination analysis because of its desirable marginal and hierarchical properties. In addition, the integrated nested Laplace approximation is considered as an alternative to Markov chain Monte Carlo sampling and the two methodologies are compared under specific modelling assumptions. The case-study is based on 2001 Belgian census data and focuses on a large, sparsely distributed origin–destination matrix containing trip information for 308 Flemish municipalities. [less ▲]

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See detailPlace de la vitamine D native en dialyse
DELANAYE, Pierre ULg; BOUQUEGNEAU, Antoine ULg; KRZESINSKI, Jean-Marie ULg et al

in Néphrologie & Thérapeutique (in press)

Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first ... [more ▼]

Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first hydroxylation in the liver, and a second one in the kidney. Next to its action on bone metabolism, vitamin D also possesses pleiotropic actions on cardiovascular, immune and neurological systems as well as antineoplastic activities. End-stage renal disease (ESRD) is also associated with a decrease in vitamin D activity by mechanisms including the increase of plasma phosphate concentration, secretion of FGF- 23 and decrease in 1a-hydroxylase activity. The prevalence of 25 hydroxy-vitamin D deficiency depends on the chosen cut-off value to define this lack. Currently it is well established that a patient has to be substituted when 25 hydroxy-vitamin D level is under 30 ng/mL. The use and monitoring of 1.25 hydroxy-vitamin D is still not recommended in routine practice. The goals of vitamin D treatment in case of ESRD are to substitute the deficiency and to prevent or treat hyperparathyroidism. Interest of native vitamin D in first intention is now well demonstrated. This review article describes the vitamin D metabolism and physiology and also the treatment for vitamin D deficiency in ESRD population. [less ▲]

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See detailWhen women support the patriarchal family. The dynamics of marriage in a Gécamines mining camp (Katanga province, DR Congo)
Rubbers, Benjamin ULg

in Journal of Historical Sociology (in press)

Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long ... [more ▼]

Based on ethnographic research among the ex-Gécamines workers of Panda (Likasi, DR Congo), this article studies the dynamics of the spousal relationship in a post-industrial context that has been long characterized by paternalism. The results of this research suggest that, though men and women living in this mining community talk about their spousal relationships by invoking the ideal of Christian marriage promoted during the colonial period, in practice such relationships faced important changes following Congolese independence in 1960. The nationalization and subsequent dramatic decline of Gécamines caused changes which directly affected three central dimensions of the colonial family model, namely monogamy, the ideal of domesticity, and male authority. If men and women continue to reference this model, it is because, in times of growing poverty, it allows spouses to remind one other of their respective duties as docile housewives and responsible husbands, and to command respect as virtuous Christian families in the local community. [less ▲]

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See detailAbout the Uniform Hölder Continuity of Generalized Riemann Function
Bastin, Françoise ULg; Nicolay, Samuel ULg; Simons, Laurent ULg

in Mediterranean Journal of Mathematics (in press)

In this paper, we study the uniform H\"{o}lder continuity of the generalized Riemann function~$R_{\alpha,\beta}$ (with $\alpha>1$ and $\beta>0$) defined by \[ R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac ... [more ▼]

In this paper, we study the uniform H\"{o}lder continuity of the generalized Riemann function~$R_{\alpha,\beta}$ (with $\alpha>1$ and $\beta>0$) defined by \[ R_{\alpha,\beta}(x)=\sum_{n=1}^{+\infty}\frac{\sin(\pi n^\beta x)}{n^\alpha},\quad x\in\mathbb{R}, \] using its continuous wavelet transform. In particular, we show that the exponent we find is optimal. We also analyse the behaviour of~$R_{\alpha,\beta}$ as $\beta$ tends to infinity. [less ▲]

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See detailA mysterious giant ichthyosaur from the lowermost Jurassic of Wales
Martin, Jeremy E; Vincent, Peggy; Suan, Guillaume et al

in Acta Palaeontologica Polonica (in press)

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic ... [more ▼]

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic. Timing and causes of this demise and the subsequent rapid radiation of the diverse, but less disparate, parvipelvian ichthyosaurs are still unknown, notably because of inadequate sampling in strata of latest Triassic age. Here, we describe an exceptionally large radius from Lower Jurassic deposits at Penarth near Cardiff, South Wales (UK) the morphology of which places it within the giant Triassic shastasaurids. A tentative total body size estimate, based on a regression analysis of various complete ichthyosaur skeletons, yields a value of 12-15 m. The specimen is substantially younger than any previously reported last known occurrences of shastasaurids and implies a Lazarus range in the lowermost Jurassic for this ichthyosaur morphotype. [less ▲]

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See detailLes états spatio-temporels d'existence et de présence
Hallot, Pierre ULg; Stewart, Kathleen; Billen, Roland ULg

in Revue Internationale de Géomatique = International Journal of Geomatics and Spatial Analysis (in press)

This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an ... [more ▼]

This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an analysis of the spatiotemporal states of existence and presence for a geographical object. Then, we combine the spatiotemporal states to define a comprehensive set of life and motion configuration. The proposed model serves as formal basis to perform spatiotemporal queries by retrieving selected patterns in the life and motion configurations. The research is applied to the organization of a scientific conference, in doing so we are able to define the relationships that exist between an event located in space and time and mobiles objects evolving within the space, i.e. the conference participants. [less ▲]

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See detailInternet facilite-t-il chez les étudiants du supérieur un apprentissage de plus en plus autorégulé ?
Poumay, Marianne ULg

in Revue Internationale des Technologies en Pédagogie Universitaire (in press)

The article specifies the meaning of “self-regulated learning”, then illustrates, first in course then in a program, a few practices using Internet as a support for learning. It underlines in those ... [more ▼]

The article specifies the meaning of “self-regulated learning”, then illustrates, first in course then in a program, a few practices using Internet as a support for learning. It underlines in those practices the growing importance of self-regulated learning. It advocates for supporting, mentoring the students in their development of that self-regulation, often implicit and considered granted in the Internet based course environments. [less ▲]

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See detailOsteoporosis in patients taking selective serotonin reuptake inhibitors: a focus on fracture outcome
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Endocrine (in press)

Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of ... [more ▼]

Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of depressive symptoms among older adults because of their presumed favorable adverse effect profile. However, they could have deleterious effects on the bone. Evidence from longitudinal, crosssectional, and prospective cohort studies suggests that the use of antidepressants at therapeutic doses is associated with decreased bone mineral density and increased fracture risk. The association between SSRIs use and fracture risk could potentially differ depending on dose, exposure duration, time of exposure, age, or sex. However, the risk of fracture declined rapidly after discontinuation of use of SSRIs. The evidence now seems sufficient to consider adding SSRIs to the list of medications that contribute to osteoporosis. In practice, assessment of risk factor for osteoporosis or fractures could be made taking into account age, gender, duration, and severity of depression, length of SSRI treatments, and other concurrent risk factors. [less ▲]

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See detailFish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries
Castano, Argelia; Cutanda, Francisco; Esteban, Marta et al

in Environmental Research (in press)

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential ... [more ▼]

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-​levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-​child pairs from 17 European countries using a strictly harmonized protocol for mercury anal. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster anal. of consumption habits of the mother-​child pairs, the DEMOCOPHES cohort can be classified into two branches of approx. similar size: one with high fish consumption (H) and another with low consumption (L)​. All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-​child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concn. between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-​child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish contribute significantly to the mercury levels in hair. We conclude that addnl. studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster anal. also showed that 95​% of mothers who consume once per wk fish only, and no other marine products, have mercury levels 0.55 μg​/g. Thus, the 95th percentile of the distribution in this group is only around half the US-​EPA recommended threshold of 1 μg​/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an addnl. dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements. [less ▲]

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See detailDiversity of germination strategies and dormancy of graminoid and forb species of campo rupestre grasslands
Le Stradic, Soizig ULg; Silveira, Fernando A. O.; Buisson, Elise et al

in Austral Ecology (in press)

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See detailDietary early-life exposure to contaminated eels does not impair spatial cognitive performances in adult offspring mice as assessed in the Y-maze and the Morris water maze
Dridi, ImenI; Leroy, Delphine; Guignard, Cedric et al

in Nutrition Research (in press)

Many environmental contaminants are introduced via the diet and may act as neurotoxins and endocrine disrupters, especially influencing growing organisms in early life. The purpose of this study was to ... [more ▼]

Many environmental contaminants are introduced via the diet and may act as neurotoxins and endocrine disrupters, especially influencing growing organisms in early life. The purpose of this study was to examine whether dietary exposure of dams to fish naturally contaminated with xenobiotics, especially with polychlorinated biphenyls (PCBs) and heavy metals (e.g. mercury and lead), resulted in cognitive function deficits in adult offspring mice. Daily, four groups of dams (n = 10/group) ingested standard diet plus paste with/without eels, during gestation and lactation, from gestational day (GD) six until post natal day (PND) 21 (weaning). Dams orally ingested a standardized amount of eel (0.8 mgkg-1 d-1) containing the six non-dioxin-like (NDL) PCBs (σ6 NDL-PCBs: 28, 52, 101, 138, 153, and 180) at 0, 85, 216, and 400 ngkg-1 d-1. Results showed that early-life exposure to contaminated eels did not (compared to non-exposed controls) impair immediate working memory in the Y-maze in the offspring assessed at PND 38. Furthermore, it did not significantly impact spatial learning and retention memory as measured in the Morris water maze in adult offspring mice (PND 120-123). Our results suggest that perinatal exposure to contaminated eels does not affect spatial cognitive performances, as assessed by the Y-maze and Morris water maze at adult age. Adverse effects of xenobiotics reported earlier might be camouflaged by beneficial eel constituents, such as n-3 fatty acids. However, additional studies are needed to differentiate between potential positive and negative effects following consumption of food items both rich in nutrients and contaminants. © 2014 Elsevier Inc. [less ▲]

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See detailOut of Himalaya: the impact of past Asian environmental changes on the evolutionary and biogeographical history of Dipodoidea (Rodentia)
Pisano, Julie ULg; Condamine, Fabien L.; Lebedev, Vladimir et al

in Journal of Biogeography (in press)

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See detailLa sécurité affective chez l'enfant en milieu résidentiel : Des soins du corps au bien être émotionnel
Aprile, Pauline ULg; Englebert, Jérôme ULg; Gauthier, Jean-Marie ULg

in Evolution Psychiatrique (in press)

Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to ... [more ▼]

Objectives - This review studies the concept of affective security in children living outside of their family environment by a brief exposition of its practical illustration in institution. We want to show that sufficient affective security can be achieved even in children institutionalized with major attachment difficulties. Method - We will first examine the original meaning of the concept by a theoretical review of its evolution over the years in the literature. Then, we will consider various questions concerning the legitimacy of institutionalization in link with affective security through a case analysis illustrating the issue. We will finally end by mentioning the main practical implications about the optimization of affective security in children institutionalized. Results - It is foremost by the predictable and expected daily acts posed by the professional caregivers in institution that the child may find sufficient affective security, generating emotional well-being and ultimately, an overall adequate development. Discussion – Children early separated from their family home to be placed in residential institution most often suffer from serious difficulties in terms of attachment to others. In this context, the institution has to deal with a specifically challenge: that is, to help the child to (re-)find sufficient internal security to allow him to grow on solid foundations. The institutional life which replaces family life primarily consists of an organizational structure that seeks to make child life as predictable as possible so that it has the necessary daily benchmarks to evolve adequately. Conclusion – In the everyday life in institution, the professionals struggling with children’s attachment disorders constantly try to achieve a right emotional-body balance through their psycho-educational practices with the child deprived of secure attachment strategies. [less ▲]

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See detailPhénoménologie autrichienne: le programme de Brentano
Dewalque, Arnaud ULg

in Austriaca (in press)

It is usual to think of the spectacular development of the Brentano School in Austria as being tied to the rise of a specific research program, which is sometimes dubbed “Austrian phenomenology”. I ... [more ▼]

It is usual to think of the spectacular development of the Brentano School in Austria as being tied to the rise of a specific research program, which is sometimes dubbed “Austrian phenomenology”. I discuss here some evidences for the existence of such a program. In the discussion, I highlight two claims which I take to be constitutive of the Brentanian phenomenology. The first one is the epistemological claim according to which our concepts all have an empirical origin, which has to be located in the experience we have of our own mental states. The second one is the methodological claim according to which describing a mental phenomenon P is nothing but analysing P, where “analysing P” simply means “distinctly perceiving all the constituents of P”. Although a deeper insight in those two claims would require considerable further investigations, I suggest they should be part of the picture when it comes to adjudicating on the specificity of the Brentanian program. [less ▲]

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See detailVitamin D status after a high dose of cholecalciferol in healthy and burn subjects
ROUSSEAU, Anne-Françoise ULg; DAMAS, Pierre ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a ... [more ▼]

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a cholecalciferol (VD3) bolus on VD status in adult burn patients (Group B, GB) after admission, compared to healthy subjects (Group H, GH). Methods: Both groups received an oral dose of 100,000 IU VD3. Blood samples were collected before (D0) and 7 days (D7) after bolus to measure 250H-D, 1,25(OH)2-D, parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). Albumin (ALB) and VD binding protein (DBP) were measured and used to calculate free 25OH-D level. Data were expressed as median (min–max) or proportions. Results: A total of 49 subjects were included: 29 in GH and 20 in GB. At D0, prevalence of VD deficiency was higher in GB: 25OH-D was 21.5 (10.1–46.3) ng/ml in GH vs 11 (1.8–31.4) ng/ml in GB. DBP and ALB were lower in GB. At D7, DBP was stable in both groups while ALB decreased in GB. 25OH-D increased by 66.6 (13.5–260.3)% in GH. In GB, changes in 25OH-D extended from 36.7% to 333.3% with a median increase of 33.1%. Similar changes were observed in each group for free 25OH-D. High FGF23 levels were observed in GB. Conclusions: This study highlighted the differences in VD status and in response to a high dose VD3 in burn patients when compared to healthy patients. Pitfalls in VD status assessment are numerous during acute burn care: 25OH-D measurement needs cautious interpretation and interest of free 25OH-D is still questionable. They should not prevent burn patients to receive VD supplements during acute care. Higher doses than general recommendations should probably be considered. [less ▲]

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailCost-effectiveness of vitamin D and calcium supplementation in the treatment of elderly women and men with osteoporosis.
Hiligsmann, Mickaël ULg; Ben Sedrine, Wafa; Bruyère, Olivier ULg et al

in European journal of public health (in press)

BACKGROUND: The supplementation with vitamin D and calcium has been recommended for elderly, specifically those with increased risk of fractures older than 65 years. This study aims to assess the cost ... [more ▼]

BACKGROUND: The supplementation with vitamin D and calcium has been recommended for elderly, specifically those with increased risk of fractures older than 65 years. This study aims to assess the cost-effectiveness of vitamin D and calcium supplementation in elderly women and men with osteoporosis and therefore to assess if this recommendation is justified in terms of cost-effectiveness. METHODS: A validated model for economic evaluations in osteoporosis was used to estimate the cost per quality-adjusted life-year (QALY) gained of vitamin D/calcium supplementation compared with no treatment. The model was populated with cost and epidemiological data from a Belgian health-care perspective. Analyses were conducted in women and men with a diagnosis of osteoporosis (i.e. bone mineral density T-score </=-2.5). A literature search was conducted to describe the efficacy of vitamin D and calcium in terms of fracture risk reduction. RESULTS: The cost per QALY gained of vitamin D/calcium supplementation was estimated at euro40 578 and euro23 477 in women and men aged 60 years, respectively. These values decreased to euro7912 and euro10 250 at the age of 70 years and vitamin D and calcium supplementation was cost-saving at the age of 80 years, meaning that treatment cost was less than the costs of treating osteoporotic fractures of the no-treatment group. CONCLUSION: This study suggests that vitamin D and calcium supplementation is cost-effective for women and men with osteoporosis aged over 60 years. From an economic perspective, vitamin D and calcium should therefore be administrated in these populations including those also taking other osteoporotic treatments. [less ▲]

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See detailMaximal bifix decoding
Berthé, Valérie; De Felice, Clelia; Dolce, Francesco et al

in Discrete Mathematics (in press)

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See detailWelcome to papers from the Second International Meeting of Agora Paleobotanica
Cascales - Miñana, Borja ULg; Diez, José B.

in Historical Biology (in press)

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See detailLa manie et la mélancolie comme crises de l’identité narrative et de l’intentionnalité
Englebert, Jérôme ULg; Stanghellini, Giovanni

in Evolution Psychiatrique (in press)

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the ... [more ▼]

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the concepts of "narrative identity" and "intentionality". Method: From clinical cases and with reference to various theoretical models derived from phenomenological psychopathology, we discuss similarities and differences between mania and melancholia. Results: Narrative identity is based on a double movement: that of the enunciation of a speech focused on his history and that of an act of creation. From different clinical situations, we find that: (1) the melancholic retains the ability to elaborate a narrative about his history but the creative dimension of this narrative is absent, and (2) conversely, the manic experiences only the creative dimension. Discussion: Intentionality, as the tendency of consciousness to move toward something beyond itself, proves to be the center of the manic existence without being able to set itself within the boundaries of factual constraints. The melancholic, conversely, experiences an existence in which consciousness has lost its capacity to aim beyond itself. Conclusions: Melancholia and mania are quite specific forms of being-in-world with particular identity and temporal experiences. These two states share a fundamental psychopathological feature, that we named here “manque chiasmatique”: they are disorders of the intentional movement that constitutes narrative identity, that is, of the dialectics between the rootedness (“enracinenment”) of self in its past and the possibility of creation of a new identity. [less ▲]

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See detailMercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project
Esteban, Marta; Schindler, Birgit K.; Jiménez-Guerrero, José A. et al

in Environmental Research (in press)

Human biomonitoring (HBM) is an effective tool for assessing actual exposure to chemicals that takes into account all routes of intake. Although hair analysis is considered to be an optimal biomarker for ... [more ▼]

Human biomonitoring (HBM) is an effective tool for assessing actual exposure to chemicals that takes into account all routes of intake. Although hair analysis is considered to be an optimal biomarker for assessing mercury exposure, the lack of harmonization as regards sampling and analytical procedures has often limited the comparison of data at national and international level. The European-funded projects COPHES and DEMOCOPHES developed and tested a harmonized European approach to Human Biomonitoring in response to the European Environment and Health Action Plan. Herein we describe the quality assurance program (QAP) for assessing mercury levels in hair samples from more than 1800 mother–child pairs recruited in 17 European countries. To ensure the comparability of the results, standard operating procedures (SOPs) for sampling and for mercury analysis were drafted and distributed to participating laboratories. Training sessions were organized for field workers and four external quality-assessment exercises (ICI/EQUAS), followed by the corresponding web conferences, were organized between March 2011 and February 2012. ICI/EQUAS used native hair samples at two mercury concentration ranges (0.20–0.71 and 0.80–1.63) per exercise. The results revealed relative standard deviations of 7.87–13.55% and 4.04–11.31% for the low and high mercury concentration ranges, respectively. A total of 16 out of 18 participating laboratories the QAP requirements and were allowed to analyze samples from the DEMOCOPHES pilot study. Web conferences after each ICI/EQUAS revealed this to be a new and effective tool for improving analytical performance and increasing capacity building. The procedure developed and tested in COPHES/DEMOCOPHES would be optimal for application on a global scale as regards implementation of the Minamata Convention on Mercury. [less ▲]

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See detailMoyens et enjeux d’une approche didactique des Illuminations
Saint-Amand, Denis ULg

in Parade Sauvage (in press), 25

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See detailEnjeux politiques et critiques d'une philosophie des normes
Caeymaex, Florence ULg; Pieron, Julien ULg

in Dissensus (in press), 6(printemps 2014),

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See detailL’acte incendiaire, son sujet et sa signification : propositions à partir du Saint Genet de Jean-Paul Sartre
Englebert, Jérôme ULg

in Annales Médico-Psychologiques (in press)

Objectives In this paper we studied fire setters with the hermeneutics’ method from the philosophy of Jean-Paul Sartre. In the psychobiography of Jean Genet, the philosopher raises issues of the ... [more ▼]

Objectives In this paper we studied fire setters with the hermeneutics’ method from the philosophy of Jean-Paul Sartre. In the psychobiography of Jean Genet, the philosopher raises issues of the infractional acting and its social meaning. Methods After recalling the basic notions of international literature about fire setters (including confusion with pyromania, diagnostic problems proposed by the DSM IV and the concept of "communicative arson"), we propose phenomenological and existential clues to discuss the act and its meaning. It is the unlawful act that is analysed and more specifically the arson. We propose different analysis than the psychic causality which is inspired by psychoanalysis. The criminogenesis gives way to a questioning of identity, about the place of fire in the subject’s history and within its relationships to others. As proposed by Sartre, the paradigm of this research is to consider the meaning "as the return of the future in the present". The second field of this study is an analysis of three clinical cases. These cases are the result of a forensic practice. The method is focused on the analysis of a narrative and autobiographical production. By this way we studied the temporal process of these three arsonists. Results A comparative reading of the psychobiography of Jean Genet written by Sartre and of the situation of arsonists gives accurate information. The "criminogenesis" gives way to a questioning of identity. In this way we discuss the meaning of fire in the subject's history and within its relationship to others. We highlight the inscription of the act in the social and constitutive process of the individual. From the clinical material, the author demonstrates a link between arson and construction of identity. Identity is considered as a dialectic between “ipse” and “idem”, as suggested by Ricœur. We can therefore consider the real sense that the arson has from the perspective of the actor but also from the viewpoint of the society and these conceptions may be similar or different. In clinical practice, we recommend to pay special attention to how the fire is part of the biography of the patient. Conclusions The fascination for fire is a source of meaning which can be radically different depending on whether we consider the external interpreter (the world or the clinician) or the author of the action. The basic principles of hermeneutics, as described by Gadamer and Ricœur, are to demonstrate that the understanding and the interpretation are not only the methods used in the human sciences but are also part of the fundamental processes inherent in human nature. Hermeneutics in general is the opposite of a doctrine of truth. It rather seeks to show arbitrarily how the interpretation and the search for meaning are paradigmatic of the human experience. [less ▲]

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See detailHeat can erase epigenetic marks of vernalization in Arabidopsis
Bouché, Frédéric ULg; Detry, Nathalie ULg; Périlleux, Claire ULg

in Plant Signaling & Behavior (in press)

Vernalization establishes a memory of winter that must be maintained for weeks or months in order to promote flowering the following spring. The stability of the vernalized state varies among plant ... [more ▼]

Vernalization establishes a memory of winter that must be maintained for weeks or months in order to promote flowering the following spring. The stability of the vernalized state varies among plant species and depends on the duration of cold exposure. In Arabidopsis thaliana, winter leads to epigenetic silencing of the floral repressor gene FLOWERING LOCUS C (FLC) and the duration of cold is measured through the dynamics of chromatin modifications during and after cold. The growing conditions encountered post-vernalization are thus critical for the maintenance of the vernalized state. We reported that high temperature leads to devernalization and, consistently, to FLC reactivation in Arabidopsis seedlings. Here we show that the repressive epigenetic mark H3K27me3 decreases at the FLC locus when vernalized seedlings are grown at 30°C, unless they were first exposed to a stabilizing period at 20°C. Ambient temperature thus controls the epigenetic memory of winter. [less ▲]

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See detailScreening Ethiopia: A preliminary study of Ethiopian film production’s history and contemporary developments
Jedlowski, Alessandro ULg

in Journal of African Cinemas (in press)

Since the early 2000s, Ethiopia has witnessed the rapid growth of a local digital film industry whose economic model is similar to the one adopted by other industries of this kind emerged in African ... [more ▼]

Since the early 2000s, Ethiopia has witnessed the rapid growth of a local digital film industry whose economic model is similar to the one adopted by other industries of this kind emerged in African countries such as Nigeria, Ghana and Tanzania. Films are shot in digital format, are independently funded and commercially-driven, use Amharic as main language and target local and diasporic audiences. Unlike other productions of this kind around the continent, however, Ethiopian video films are firstly released in the large cinema theatres that characterize Addis Ababa’s urban landscape, and later circulate via VCDs, in Ethiopia, and in internet, throughout the diaspora. As this essay will argue, this aspect gives to the Ethiopian video film phenomenon a number of important specificities which make the study of Ethiopian film production and distribution particularly interesting. Furthermore, within a context defined by a relatively tight governmental control on media production and circulation, the emergence of this phenomenon is introducing important transformations, and modifying the way locally-produced media are perceived and consumed within the Ethiopian public sphere. While being commercially oriented, in fact, videos do produce a social and moral commentary which portrays, and in some cases criticizes, the way the society has transformed over the past few years. This article presents the preliminary results of an ongoing research on the raising Ethiopian digital film industry, conducted as part of a post-doctoral research project which analyses and compares the economy of digital filmmaking in a few sub-Saharan African countries. The data presented here have been collected through interviews, archival research and participant observation on film sets and distribution venues during a three months research stay in Addis Ababa between the end of 2013 and the beginning of 2014. The paper is divided into four main sections: the first two trace the history of filmmaking in Ethiopia and the emergence of the video phenomenon within this context, the third focuses on the analysis of the video industry’s economy and describes its main specificities, and the fourth presents an overview of the main narrative and aesthetic trends emerged within the context of the Ethiopian film production until today. [less ▲]

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See detailWorking memory deficits in developmental dyscalculia: the importance of serial order.
Attout, Lucie ULg; Majerus, Steve ULg

in Child Neuropsychology : A Journal on Normal & Abnormal Development in Childhood & Adolescence (in press)

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailEnvironnements Personnels d’Apprentissage : exploration des représentations et usages d’étudiants de l’enseignement supérieur
Denis, Brigitte ULg; Joris, Noémie ULg

in Sciences et technologies de l'information et de la communication pour l'éducation et la formation (in press)

Currently, it is difficult for a student to pursue higher education without using a digital environment. This leads to the emergence the concept of Personal Learning Environment (PLE). The authors define ... [more ▼]

Currently, it is difficult for a student to pursue higher education without using a digital environment. This leads to the emergence the concept of Personal Learning Environment (PLE). The authors define it and consider his competition or complementarity with the digitals institutional environments. They report exploratory study results on students’ representations about their numeric learning environments and their interests about them. Data comes from questionnaires and interviews. Their analysis shows different profiles related to the PLE. Linking the results to learning theories and aspects of technical and educational design, they propose further investigation and development related to the complementarity of PLE and institutional learning environments (ILE). [less ▲]

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See detailNGOs and female circumcision in Egypt. An anthropological enquiry.
Mescoli, Elsa ULg

in Journal of the Anthropology of the Contemporary Middle East and Central Eurasia (in press)

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the ... [more ▼]

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the circumcision of a ten-year-old child living in this very same city. Discourses around female circumcision were not new in Egypt and in the international community, but what was considered as a new episode of a recurrent scandal (not the last one indeed) led to enhance the "war against bad government"[1]. A war fought by means of ideological weapons produced by expert knowledges among which the medical and the feminist ones. The assignment of a value to the state of integrity of the female body and to the women freedom of choice, both designed according to Western canons, led to different actions to “save” Egyptian women. In this context, development agencies fosters a widespread representation of the victim, constituted by the woman mutilated body. Such representation is functional to put in place programs which do not guarantee a freedom of choice, but rather require adherence to another female model, one that defines the "modern" woman. My article, based on ethnographic experience, aims at highlighting the complexity of such dynamics and the role played by humanitarianism within them. Female body becomes the arena where local and international economic powers operate, disregarding a real understanding of the practice, its meanings and its eventual change. ________________________________________ [1] Foucault, Michel. La nascita della clinica. Il ruolo della medicina nella costituzione delle scienze umane, Einaudi, Torino 1969: 48. [less ▲]

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See detailThe strength of multi-row models
Louveaux, Quentin ULg; Poirrier, Laurent; Salvagnin, Domenico

in Mathematical Programming Computation (in press)

We develop a method for computing facet-defining valid inequalities for any mixed-integer set PJ. Our practical implementation does not return only facet- defining inequalities, but it is able to find a ... [more ▼]

We develop a method for computing facet-defining valid inequalities for any mixed-integer set PJ. Our practical implementation does not return only facet- defining inequalities, but it is able to find a separating cut whenever one exists. The separator is not comparable in speed with the specific cutting-plane generators used in branch-and-cut solvers, but it is general-purpose. We can thus use it to compute cuts derived from any reasonably small relaxation PJ of a general mixed- integer problem, even when there exists no specific implementation for computing cuts with PJ. Exploiting this, we evaluate, from a computational perspective, the usefulness of cuts derived from several types of multi-row relaxations. In particular, we present results with four different strengthenings of the two-row intersection cut model, and multi-row models with up to fifteen rows. We conclude that only fully-strengthened two-row cuts seem to offer a significant advantage over two-row intersection cuts. Our results also indicate that the improvement obtained by going from models with very few rows to models with up to fifteen rows may not be worth the increased computing cost. [less ▲]

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See detailRecurrent pulsations in Saturn’s high latitude magnetosphere
Mitchell, D.G.; Carbary, J.F.; Bunce, E.J. et al

in Icarus (in press)

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See detailTen years of Martian nitric oxide nightglow observations
Stiepen, Arnaud ULg; Gérard, Jean-Claude ULg; Gagné, Marie-Eve et al

in Geophysical Research Letters (in press)

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See detailAnalogical mapping across modalities in children with specific language impairment (SLI)
Leroy, Sandrine ULg; Parisse, Christophe; Maillart, Christelle ULg

in Research in Developmental Disabilities (in press)

Analogical mapping is a domain-general cognitive process found in language development, and more particularly in the abstraction of construction schemas. Analogical mapping is considered as the general ... [more ▼]

Analogical mapping is a domain-general cognitive process found in language development, and more particularly in the abstraction of construction schemas. Analogical mapping is considered as the general cognitive process which consists in the alignment of two or several sequences in order to detect their common relational structure and generalize it to new items. The current study investigated analogical mapping across modalities in children with specific language impairment (SLI). Nineteen children with SLI and their age-matched peers were administered two tasks: a linguistic analogical reasoning task (composed of syllables) and a similar non-linguistic analogical reasoning task (composed of pictures). In the two tasks, the items presented were divided into two groups: items with perceptual cues and items without perceptual cues. Children had to complete a sequence sharing the same relational structure as previously presented sequences. Results showed an expected group effect with poorer performance for children with SLI compared to children with typical language development (TLD). Results corroborate hypotheses suggesting that children with SLI have difficulties with analogical mapping, which may hinder the abstraction of construction schemas. Interestingly, whereas no interaction effect between group and modality (linguistic vs. non-linguistic) was revealed, a triple interaction Group*Modality*Perceptual support was observed. In the non-linguistic task, the performance of children with SLI was the same for items with and without perceptual clues, but in the linguistic task they performed more poorly for items without perceptual cues compared to items with perceptual cues. The results and limits of the study are discussed. [less ▲]

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See detailNutritive value of Adenodolichos rhomboideus leaves compared with Leucaena leucocephala and Stylosanthes guianensis forages in indigenous goats in Lubumbashi (DR Congo).
Tshibangu, Muamba Innocent; Nsahlai, Ignatus Verla; Kiatoko, Mangeye Honoré et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Forage from three species (Adenodolichos rhomboideus, Leucaena leucocephala, Stylosanthes guianensis) were evaluated by determining chemical composition, voluntary intake and apparent in vivo ... [more ▼]

Forage from three species (Adenodolichos rhomboideus, Leucaena leucocephala, Stylosanthes guianensis) were evaluated by determining chemical composition, voluntary intake and apparent in vivo digestibility of dry matter (DM), organic matter (OM), crude protein (CP), neutral detergent fibre (NDF) and acid detergent fibre (ADF). Six goats (17.1±0.7 kg) were used in 3 x 3 double latin square design to determine the digestibility and intake of the three forages. Forage from S. guianensis had lower (p<0.001) CP content than L. leucocephala forage and A. rhomboideus leaves. Fibres content (ADF and NDF) were lower (p<0.001) in L. leucocephala (35%) forage than A. rhomboideus (59.5%) leaves and S. guianensis forages (56.5%). L. leucocephala forage was superior in CP, Ash, EE concentrations, digestibility and voluntary intake of CP. A. rhomboideus leaves had lower (p<0.05) apparent digestibility and intake of DM. Digestible CP intake were similar between A. rhomboideus leaves and S. guianensis forages. Low digestibility and voluntary intake of A. rhomboideus leaves may be due to negative effect of anti-nutritional factor such as tannin. Digestible CP was similar for A. rhomboideus leaves and S. guianensis forage. [less ▲]

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See detailSimultaneous enforcement of constraints at position and velocity levels in the nonsmooth generalized-alpha scheme
Bruls, Olivier ULg; Acary, Vincent; Cardona, Alberto

in Computer Methods in Applied Mechanics & Engineering (in press)

This paper presents a formalism for the transient simulation of nonsmooth dynamic mechanical systems composed of rigid and flexible bodies, kinematic joints and frictionless contact conditions. The ... [more ▼]

This paper presents a formalism for the transient simulation of nonsmooth dynamic mechanical systems composed of rigid and flexible bodies, kinematic joints and frictionless contact conditions. The proposed algorithm guarantees the exact satisfaction of the bilateral and unilateral constraints both at position and velocity levels. Thus, it significantly differs from penalty techniques since no penetration is allowed. The numerical scheme is obtained in two main steps. Firstly, a splitting method is used to isolate the contributions of impacts, which shall be integrated with only first-order accuracy, from smooth contributions which can be integrated using a higher order scheme. Secondly, following the idea of Gear, Gupta and Leimkuhler, the equations of motion are reformulated so that the bilateral and unilateral constraints appear both at position and velocity levels. After time discretization, the equations of motion involve two complementarity conditions and it can be solved at each time step using a monolithic semi-smooth Newton method. The numerical behaviour of the proposed method is studied and compared to other approaches for a number of numerical examples. It is shown that the formulation offers a unified and valid approach for the description of contact conditions between rigid bodies as well as between flexible bodies. [less ▲]

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See detailAnorexie et intersubjectivité : Étude phénoménologique et éthologique
Englebert, Jérôme ULg

in Annales Médico-Psychologiques (in press)

Objective: Based on the case study of Jeanne, the objective of this article is to study patterns of anorexic people’s specific being-in-the-world. We seek to identify the core vulnerability features of ... [more ▼]

Objective: Based on the case study of Jeanne, the objective of this article is to study patterns of anorexic people’s specific being-in-the-world. We seek to identify the core vulnerability features of anorexic existence, beyond the dimension of feeding alone. The identification of a psychopathological structure will result in a better understanding of Jeanne’s clinical situation and will help to formulate psychotherapeutic and prophylactic recommendations. Method: A phenomenological and ethological approach allows us to see past the strictly medical symptoms (eating disorder). The evolutionary perspective highlights the adaptive dimension of this disorder (e.g., in extreme situations such as famine). Specifically, Demaret’s ethological hypothesis identifies altruism (feeding altruism and generalized altruism) as the core feature of anorexic conduct. Phenomenological reflection (phenomenological psychopathology and phenomenological philosophy) appears to complement the ethological approach. Phenomenology distinguishes two kinds of bodies: the Leib (emotional, subjective and experienced in the first person) and the Körper (devitalized, objective and experienced in the second person). Merleau-Ponty’s works highlight the difference between the touching body and the touched body. These proposals show the problematic of the other in body configuration. It is in precisely this connection that anorexic existence is specific. Sartre’s phenomenology and the lived-body-for-others is the final step of our reasoning to arrive at a configuration of intersubjectivity. Results: The analysis of Jeanne’s case, combined with ethological and phenomenological perspectives, demonstrates that the real psychopathological structure of anorexic subjectivity rests on specific interaction modes. The notions of altruism, lived-body-for-others, and intersubjectivity highlight an emotional existence including shame in the eyes of others, and especially an imbalance between self-preservation and care for others. Conclusions: All our thinking suggests that so-called “denial” is a psychological mechanism that should be reconsidered. Denial is not a mechanism of anorexic subjects alone, but is also a process encountered both in the patient’s family and in the therapeutic environment. Anorexic denial is based on anosognosia and the refusal to see one’s own thinness, while other people’s denial constitutes a widespread inability to perceive the altruism and intersubjective problematic on which the existence of an anorexic subject fundamentally depends. [less ▲]

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See detailHigh concentrations of Myeloperoxidase in the equine uterus as an indicator of endometritis
Parrilla Hernandez, Sonia ULg; Ponthier, Jérôme ULg; Franck, Thierry ULg et al

in Theriogenology (in press)

Intra-luminal fluid and excessive abnormal hyper-edema are regularly used for the diagnosis of endometritis in the mare, which is routinely confirmed by the presence of neutrophils on endometrial smears ... [more ▼]

Intra-luminal fluid and excessive abnormal hyper-edema are regularly used for the diagnosis of endometritis in the mare, which is routinely confirmed by the presence of neutrophils on endometrial smears. Studies show a relation between neutrophils and myeloperoxidase (MPO), an enzyme contained in and released by neutrophils during degranulation or after cell lysis. This enzyme has been found in many fluids and tissues and associated with different inflammatory pathologies in the horse. The aims of this study were to assess the presence and concentration of MPO in the equine uterus, and to investigate its relation with neutrophils, and other clinical signs of endometritis. Mares (n=51) were evaluated for presence of intra-luminal fluid and excessive endometrial edema before breeding, and a small volume lavage and cytology samples were obtained. From 69 cycles, supernatant of the uterine flushes was analysed with a specific equine MPO ELISA assay to measure MPO concentration. Cytology samples were used for the diagnosis of endometritis. MPO was present in the uterus of all estrus mares in highly variable concentrations. MPO concentrations were significantly (p<0.05) higher in samples with positive cytologies and in presence of intra-luminal fluid. Occasionally, some samples with negative cytologies showed high MPO concentration, but the opposite was never observed. Cycles presenting hyper-edema weren’t associated to high concentration of MPO, intra-luminal fluid or positive cytology making it a poor diagnostic tool of endometritis. [less ▲]

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See detailThe potential impact of animal protein intake on global and central obesity: evidence from the ORISCAV-LUX study
Alkerwi, A.; Sauvageot, Nicolas ULg; Buckley, J.D. et al

in Public Health Nutrition (in press)

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See detailPhylogeny, classification and species delimitation in the liverwort genus Odontoschisma (Cephaloziaceae)
Aranda, S.C.; Gradstein, S.R.; Patino, J. et al

in Taxon (in press)

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See detailValid inequalities for the single arc design problem with set-ups
Agra, Agostinho; Doostmohammadi, Mahdi; Louveaux, Quentin ULg

in Discrete Optimization (in press)

We consider a mixed integer set which generalizes two well-known sets: the single node fixed- charge network set and the single arc design set. Such set arises as a relaxation of feasible sets of general ... [more ▼]

We consider a mixed integer set which generalizes two well-known sets: the single node fixed- charge network set and the single arc design set. Such set arises as a relaxation of feasible sets of general mixed integer problems such as lot-sizing and network design problems. We derive several families of valid inequalities that, in particular, generalize the arc resid- ual capacity inequalities and the flow cover inequalities. For the constant capacitated case we provide an extended compact formulation and give a partial description of the convex hull in the original space which is exact under a certain condition. By lifting some basic inequalities we provide some insight on the difficulty of obtaining such a full polyhedral description for the constant capacitated case. Preliminary computational results are presented. [less ▲]

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See detailLe cas clinique du mois. Hémangiome épithélioïde, une tumeur osseuse rare.
Gérard, Valérie; TOMASELLA, Marco ULg; KURTH, William ULg et al

in Revue Médicale de Liège (in press)

A case of pathological hip fracture associated with an epithelioid hemangioma is reported. Epithelioid hemangioma is a benign tumor, rarely localized in a bone. When the tumor is found on the skeleton, it ... [more ▼]

A case of pathological hip fracture associated with an epithelioid hemangioma is reported. Epithelioid hemangioma is a benign tumor, rarely localized in a bone. When the tumor is found on the skeleton, it generally involves a long bone. X-ray does not permit the differenciation of epithelioid hemangioma from other,malignant, vascular tumors. Therefore,the diagnosis requires surgery. Although no consensus treatment guidelines exist, the curettage – filling is most often proposed. [less ▲]

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See detailRethinking Vulnerability Analysis and Governance with Emphasis on a Participatory Approach
Rossignol, Nicolas ULg; Delvenne, Pierre ULg; Turcanu, Catrinel

in Risk Analysis : An Official Publication of the Society for Risk Analysis (in press)

This paper draws on vulnerability analysis as it emerged as a complement to classical risk analysis, and it aims at exploring its ability of nurturing risk and vulnerability governance actions. An ... [more ▼]

This paper draws on vulnerability analysis as it emerged as a complement to classical risk analysis, and it aims at exploring its ability of nurturing risk and vulnerability governance actions. An analysis of the literature on vulnerability analysis allows us to formulate a threefold critique: first, vulnerability analysis has been treated separately in the natural and the technological hazards fields. This separation prevents vulnerability to unleash the full range of its potential, as it constraints appraisals into artificial categories and thus already closes down the outcomes of the analysis. Second, vulnerability analysis focused on assessment tools that are mainly quantitative, whereas qualitative appraisal is a key to assessing vulnerability in a comprehensive way and to informing policy-making. Third, a systematic literature review of case studies reporting on participatory approaches to vulnerability analysis allows us to argue that participation has been important to address the above, but it remains too closed down in its approach and would benefit from embracing a more open, encompassing perspective. Therefore, we suggest rethinking vulnerability analysis as one part of a dynamic process between opening-up and closing-down strategies, in order to support a vulnerability governance framework. [less ▲]

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See detailDocument Kinetic study of volatile oil of Curcuma longa L. rhizome and Carum carvi L. fruits extracted by microwave-assisted techniques using the cryogrinding
Akloul, R; Benkaci-Ali, F; Eppe, Gauthier ULg

in Journal of Essential Oil Research (in press)

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the ... [more ▼]

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the cryogrinding (CG) showed differences in yields and composition of volatile oils compared with classical grinding. HDAM–CG (CL: 1.20%, CC: 1.25%) and SDAM–CG (CL: 1.45%, CC: 1.75%) allowed extraction of substantial amounts of volatile oils in less time compared with HDAM (CL: 0.6%, CC: 1.00%) and SDAM (CL: 0.90%, CC: 1.00%). In addition, the major amounts of volatile oils were globally obtained during the first 5 and 10 minutes of extraction for CL and CC, respectively. A kinetic study of essential oils extraction from CL and CC was quantitatively performed. The composition of the major components and family classes present a significant variation with the extraction time. Essential oils extracted by these two methods were quantitatively (yield) and qualitatively [aromatic profile by gas chromatography (GC) and GC–mass spectrometry (GC–MS)] analyzed. There were differences, especially in the major compounds ar-turmerone (HDAM: 46.00–57.96%, HDAM–CG: 30.85–60.32%) and β-turmerone (HDAM: 14.43–16.74%, HDAM–CG: 10.46–15.77%) for CL, and limonene (HDAM: 23.61–56.97%, HDAM–CG: 38.04–43.00%) and carvone (HDAM: 36.19–64.54%, CC–CG: 53.65–56.31%) for CC. [less ▲]

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See detailCaractérisation de colluvions triasiques utilisés dans l'élaboration d'ustensiles rustiques de cuisson, cas de Talatast (Région de Marrakech, Maroc)
El Boudour El Idrissi, Hicham ULg; Daoudi, Lahcen; Collin, Frédéric ULg et al

in Verres, Céramiques & Composites (in press)

The raw material used in the potter site of Talatast (Morocco) is collected from Triassic colluviums. Our study aims to characterize the mineralogical and geotechnical properties of the local clayey ... [more ▼]

The raw material used in the potter site of Talatast (Morocco) is collected from Triassic colluviums. Our study aims to characterize the mineralogical and geotechnical properties of the local clayey material before and after cooking. Our results confirm that the coarse particle size, the mineralogy of the clay fraction and the rate of fondants are suitable for the cookware material production. Defects encountered during the production are mainly related to the use of traditional ovens. Understanding the origin of the main defects could be helpful to promote the local pottery production. [less ▲]

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See detailBryophytes diversified slowly but surely since the mid-Mesozoic
Laenen, B.; Shaw, B.; Schneider, H. et al

in Nature Communications (in press)

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See detailClostridium difficile infection in elderly nursing home residents.
Rodriguez Diaz, Cristina ULg; Korsak Koulagenko, Nicolas ULg; Taminiau, Bernard ULg et al

in Anaerobe (in press), 23

Age-related changes in intestinal flora and host defences, the receipt of antibiotic treatment, and the presence of underlying diseases are some of the most common risk factors associated with Clostridium ... [more ▼]

Age-related changes in intestinal flora and host defences, the receipt of antibiotic treatment, and the presence of underlying diseases are some of the most common risk factors associated with Clostridium difficile infection. Therefore, retirement care facilities for elderly people have been pinpointed as frequent sources of contamination. There is only limited data regarding the presence and epidemiology of C. difficile in nursing homes, and this gap in the current literature emphasises the need to gain a better understanding of the situation in order to prevent the emergence of new outbreaks among this population group. [less ▲]

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See detailRituximab therapy for hairy cell leukemia : a retrospective study of 41 cases
Leclerc, Mathieu; Suarez, Felipe; Noël, Marie-Pierre et al

in Annals of Hematology (in press)

The purine analogs (PAs) cladribine and pentostatin have transformed the prognosis of hairy cell leukemia (HCL). However, some patients still relapse after PAs, or fail to reach an optimal response, and ... [more ▼]

The purine analogs (PAs) cladribine and pentostatin have transformed the prognosis of hairy cell leukemia (HCL). However, some patients still relapse after PAs, or fail to reach an optimal response, and new agents are needed to further improve treatment outcome. We retrospectively studied 41 HCL patients from 10 centers in France and Belgium, who received 49 treatment courses with the anti-CD20 monoclonal antibody rituximab. Most of the patients were treated at relapse (84 % of cases) and rituximab was combined to a PA in 41 % of cases. Overall, response rate is 90 % including 71 % complete hematologic responses (CHRs). Frontline treatment, combination therapy, and absolute neutrophil count were associated with response in multivariate analysis. Three-year relapse-free and overall survivals are 68 and 90 %, respectively. When combined to a PA, rituximab yields a 100 % response rate, even beyond frontline therapy. In contrast, response rate is only 82 % (59 % CHR) when rituximab is used alone. In this latter setting, relapse rate is 56 % and median time to relapse is 17.5 months. All eight patients who were treated two times with the antibody responded again to retreatment. We confirm the high efficacy of the combination rituximab + PA. However, when rituximab is used as monotherapy, response rate is lower and the high relapse rate is a concern. Prospective clinical trials are needed to confirm the superiority of the combination rituximab + PA over PA alone, both as frontline therapy and at relapse. [less ▲]

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailInfluence of process operating conditions on solvent thermal and oxidative degradation in post-combustion CO2 capture
Léonard, Grégoire ULg; Crosset, Cyril; Toye, Dominique ULg et al

in Computers & Chemical Engineering (in press)

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent ... [more ▼]

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data, the kinetics of monoethanolamine degradation is included into a model of the CO2 capture process. The influences of operating conditions and flowsheet improvements on solvent loss and process energy requirement are quantified and validated with pilot plant data. Oxidative degradation in the absorber is identified as the major cause of solvent loss. On the contrary, thermal degradation does not appear as a major concern. Finally, this study leads to a decrease by 10% of the process exergy requirement along with a reduction by 11% of the solvent loss, all that by using a single model. Thus, this model provides a practical tool to minimize both the energy requirement and the solvent degradation by the design of large-scale CO2 capture units. [less ▲]

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See detailDevelopment by the sol–gel process of highly dispersed Ni–Cu/SiO2 xerogel catalysts for selective 1,2-dichloroethane hydrodechlorination into ethylene
Pirard, Sophie ULg; Mahy, Julien ULg; Pirard, Jean-Paul ULg et al

in Microporous and Mesoporous Materials (in press)

Ni–Cu/SiO2 xerogel catalysts have been synthesized by cogelation of industrial tetraethoxysilane (Dynasil) and chelates of Ni and Cu with industrial 3-(2-aminoethylamino)propyltrimethoxysilane (Dynasylan ... [more ▼]

Ni–Cu/SiO2 xerogel catalysts have been synthesized by cogelation of industrial tetraethoxysilane (Dynasil) and chelates of Ni and Cu with industrial 3-(2-aminoethylamino)propyltrimethoxysilane (Dynasylan DAMO) in industrial ethanol denatured with diethyl phthalate. Despite the use of industrial grade reagents, highly dispersed bimetallic Ni–Cu/SiO2 xerogel catalysts were obtained. These samples are composed of completely accessible Ni–Cu alloy crystallites with sizes of 1.6–3.4 nm located inside silica particles exhibiting a monodisperse microporous distribution. It appears that the bimetallic complex acts as a nucleation agent in the formation of silica particles. The combination of results obtained from the calculation of the metal ratio in catalysts, H2 chemisorption and transmission electron microscopy allowed calculating the surface composition of the nickel–copper particles in Ni–Cu/SiO2 cogelled xerogel catalysts. Values obtained indicate a very pronounced surface enrichment with copper. While 1,2-dichloroethane hydrodechlorination over pure nickel mainly produces ethane, increasing copper content in bimetallic catalysts results in an increase in ethylene selectivity. The specific consumption rate of 1,2-dichloroethane decreases when copper loading increases. The turnover frequency, that is, the number of catalytic cycle per active site (nickel atom and its surrounding copper atoms) and per second, seems to be independent of surface composition of alloy particles. [less ▲]

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See detailIn situ investigation of scCO2 assisted impregnation of drug into polymer by high pressure FTIR micro-spectroscopy
Champeau, Mathilde ULg; Thomassin, Jean-Michel ULg; Jérôme, Christine ULg et al

in Analyst (in press)

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers ... [more ▼]

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers or films, subjected to supercritical CO2. Thanks to this experimental set-up, key factors governing the impregnation process can be simultaneously followed such as the swelling of the polymeric matrix, the CO2 sorption, the kinetic of impregnation and the drug loading into the matrix. Moreover, the solute/polymer interactions and the speciation of the solute can be analyzed. We have monitored in situ the impregnation of aspirin and ketoprofen into PEO (Polyethylene Oxide) platelets at T=40°C and P=5; 10 and 15 MPa. The kinetic of impregnation of aspirin was quicker than the one of ketoprofen and the final drug loading was also higher in case of aspirin. Whereas the CO2 sorption and the PEO swelling remain constant when PEO is just subjected to CO2 under isobaric conditions, we noticed that both parameters can increase while the drug impregnates PEO. Coupling these results with DSC measurements, we underlined the plasticizing effect of the drug that also leads to decrease the crystallinity of PEO in situ thus favoring the sorption of CO2 molecules into the matrix and the swelling of the matrix. The plasticizing effect increases with the drug loading. Finally, the speciation of drug was investigated considering the shift of the carboxyl bands of the drugs. Both drugs were found to be mainly homogeneously dispersed into PEO. [less ▲]

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See detailSens et signification dans l'esthétique de Mallarmé
Durand, Pascal ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (in press), 5

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See detailSoutenir le développement des compétences des enseignants du supérieur par la documentation, l’investigation et le partage des pratiques en classe
Poumay, Marianne ULg; Georges, François ULg

in Dossiers des Sciences de l'Education (Les) (in press)

L’article aborde le développement professionnel des enseignants à travers un master complémentaire en pédagogie de l’enseignement supérieur. Orientée recherche, cette formation met en œuvre les principes ... [more ▼]

L’article aborde le développement professionnel des enseignants à travers un master complémentaire en pédagogie de l’enseignement supérieur. Orientée recherche, cette formation met en œuvre les principes du courant « SoTL ». Elle préconise une documentation de ses pratiques, une investigation de type scientifique de l’apprentissage des étudiants dans sa propre classe et une production de connaissance par le partage de ses avancées. Les articles de régulation rédigés à l’issue de la formation par une cohorte de dix participants montrent leur réelle inscription dans ce courant « SoTL » ; une enquête donne par ailleurs des indices d’efficacité de la formation sur ces mêmes critères à moyen terme. [less ▲]

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See detailCost monitoring in clam farms in Coastal Nam Dinh Province of Vietnam
Bui Thi, Nga; Tran Huu, Cuong; Lebailly, Philippe ULg

in Scholars Journal of Agriculture and Veterinary Sciences (in press), Nov. 2014-Jan 2015, 2(1),

Clam farming is a strength in the agricultural development of the coastal communes in Nam Dinh province, which has developed rapidly in recent years. It has many advantages of no investment on food, low ... [more ▼]

Clam farming is a strength in the agricultural development of the coastal communes in Nam Dinh province, which has developed rapidly in recent years. It has many advantages of no investment on food, low capital in technique management, simple care, short cultured time. It could bring high profits for the farmers, create employment for labor in rural area and contribute significantly to local economy. In addition, the model of clam farming can be easily replicated so clam farming attracts a lot of attention from the coastal fishermen, policy makers and participation of scientists. However, the development of clam farming in this province is still spontaneous, without obvious planning and sustainable development strategies. In addition, market becomes more competitive. Farmers manage their farms base on experiences and depend too much on natural conditions, thus they are facing many risks. This lead to the situation of inefficiency, and affects negatively to the clam farming and environment. This research aims to study about cost monitoring in clam farms and analyze the factors affecting the cost monitoring in clam farms in Nam Dinh province. From which, suggestions to develop effectively clam farming and contribute to raise incomes for farmers were given in the next years in Nam Dinh province. [less ▲]

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See detailDynamiques transactionnelles de reconnaissance et professionnalisation des stagiaires : perspectives pour la formation initiale
Dejean, Karine ULg

in Education et Formation (in press)

Cet article prend appui sur une recherche doctorale. A partir de l’analyse de récits d’expériences marquantes, à forte charge émotionnelle, rapportées par des enseignants débutants, des schémas ... [more ▼]

Cet article prend appui sur une recherche doctorale. A partir de l’analyse de récits d’expériences marquantes, à forte charge émotionnelle, rapportées par des enseignants débutants, des schémas d’intelligibilité de ces situations vécues ont été construits. Ceux-ci rendent compte des transformations identitaires et émotionnelles des enseignants débutants au travers des dynamiques transactionnelles de reconnaissance. Ces résultats ouvrent des perspectives pour la formation initiale des enseignants et l’accompagnement des enseignants débutants. Les schémas d’intelligibilité pourront être utilisés dans une démarche de réflexivité pour faciliter le décodage de situations professionnelles à forte charge émotionnelle vécues par l’enseignant et l’aider à donner sens à ses expériences [less ▲]

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See detailIchthyosaurs from the Jurassic of Skye, Scotland
Brusatte, S. L.; Young, M. T.; Challands, T. J. et al

in Scottish Journal of Geology (in press)

Fossils of Mesozoic vertebrates are rare in Scotland, particularly specimens of marine reptiles such as plesiosaurs and ichthyosaurs. We describe a suite of ichthyosaur fossils from the Early to Middle ... [more ▼]

Fossils of Mesozoic vertebrates are rare in Scotland, particularly specimens of marine reptiles such as plesiosaurs and ichthyosaurs. We describe a suite of ichthyosaur fossils from the Early to Middle Jurassic of Skye, which to our knowledge are the first ichthyosaurs from Scotland to be described and figured in detail. These fossils span approximately 30 million years, from the Sinemurian to the Bathonian, and indicate that ichthyosaurs were a major component of Scottish marine faunas during this time. The specimens include isolated teeth that could represent the most northerly known occurrences of the widespread Sinemurian species Ichthyosaurus communis, a characteristic component of the famous Lyme Regis faunas of England, suggesting that such faunas were also present in Scotland during the Early Jurassic. An associated humerus and vertebrae from Toarcian–Bajocian-aged deposits are named as a new genus and species of basal neoichthyosaurian, Dearcmhara shawcrossi. The taxonomic affinities of this taxon, which comes from a critical but poorly sampled interval in the fossil record, suggest that non-ophthalmosaurid neoichthyosaurians dominated European assemblages around the Early–Middle Jurassic boundary, and were later replaced by ophthalmosaurids, whose radiation likely took place outside Europe. Many of these specimens were collected by amateurs and donated to museum collections, a co-operative relationship essential to the preservation of Scotland’s fossil heritage. [less ▲]

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See detailDevonian antiarch placoderms from Belgium revisited
Olive, Sébastien ULg

in Acta Palaeontologica Polonica (in press)

Anatomical, systematic, and paleobiogeographical data on the Devonian antiarchs from Belgium are reviewed, updated and completed thanks to new data from the field and re-examination of paleontological ... [more ▼]

Anatomical, systematic, and paleobiogeographical data on the Devonian antiarchs from Belgium are reviewed, updated and completed thanks to new data from the field and re-examination of paleontological collections. The material of Bothriolepis lohesti Leriche, 1931 is enhanced and the species better described. An undetermined species of Bothriolepis is recorded from the Famennian of Modave (Liège Province), one species of Asterolepis redescribed from the Givetian of Hingeon and another one described from the Givetian of Mazy (Namur Province). Grossilepis rikiki sp. nov. is recorded from the Famennian tetrapod-bearing locality of Strud (Namur Province) and from the Famennian of Moresnet (Liège Province). It is the first occurrence of Grossilepis after the Frasnian and on the central southern coast of the Euramerican continent. Its occurrence in the Famennian of Belgium may be the result of a late arrival from the Moscow Platform and the Baltic Depression, where the genus is known from Frasnian deposits. Remigolepis durnalense sp. nov. is described from the Famennian of Spontin near Durnal (Namur Province). Except for the doubtful occurrence of Remigolepis sp. in Scotland, this is the first record of this genus in Western Europe. Its occurrence in Belgium reinforces the strong faunal affinities between Belgium and East Greenland and the hypothesis of a hydrographical link between the two areas during the Late Devonian. [less ▲]

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See detailLe délit de presse à l’ère numérique
Behrendt, Christian ULg

in Revue Belge de Droit Constitutionnel [= RBDC] (in press)

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See detailRéformer la « justice de proximité ». Une comparaison entre les tribunaux coutumiers et les tribunaux de paix à Lubumbashi (R.D.Congo)
Rubbers, Benjamin ULg; Gallez, Emilie

in Critique Internationale (in press)

Dans le cadre de la stratégie des bailleurs de fonds pour restaurer un « Etat de droit » en R.D. Congo, le gouvernement de J. Kabila, élu en 2006, s’est engagé dans une importante réforme du système ... [more ▼]

Dans le cadre de la stratégie des bailleurs de fonds pour restaurer un « Etat de droit » en R.D. Congo, le gouvernement de J. Kabila, élu en 2006, s’est engagé dans une importante réforme du système judiciaire. L’une des principales ambitions de cette réforme est d’améliorer l’accès des citoyens à la justice « moderne » en remplaçant les tribunaux coutumiers par des tribunaux de paix. Basé sur une recherche collective conduite en 2010, cet article propose d’évaluer la portée de ce volet de la réforme en comparant le mode de fonctionnement concret des tribunaux coutumiers à la périphérie de Lubumbashi avec celui des tribunaux de paix dans cette même ville. Cette approche n’autorise pas seulement une critique empiriquement fondée des présupposés modernistes qui sous-tendent la réforme. Elle offre également, à une plus large échelle, un angle d’analyse original pour revenir sur le débat relatif aux systèmes de justice formels/informels qui s’est développé dans la littérature en « law and development » au cours de cette dernière décennie. [less ▲]

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See detailAnalysis of shrinkage effect on mass transfer during the convective drying of sawdust/sludge mixtures
Li, Jie; Bennamoun, Lyes; Fraikin, Laurent ULg et al

in Drying Technology (in press)

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See detailLes tensions entre langue et politique en Belgique: linguistiques ou communautaires?
Dassargues, Alix ULg; Perrez, Julien ULg; Reuchamps, Min ULg

in Revue Internationale de Politique Comparée (in press)

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have ... [more ▼]

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have regularly been referred to as linguistic by some researchers and as community-related by others. But the choice of these adjectives is not unimportant considering they frame the representations of the political issues at hand. The aim of this article is to tackle this question from the combined perspective of linguistics and political science. In the first, the article explores the genealogy of the adjectives ‘linguistic’ and ‘community-related’ as well as the multiplicity of their uses in the scientific literature. In the second part, it focuses on the ways citizens see and talk about Belgian federalism through the respective analyses of their mental representations and their conceptual metaphors. Such interdisciplinary endeavour, bringing together theoretical and empirical insights, seeks to yield a renewed understanding of the political relations in Belgium and to contribute to the debate about plurilingual societies. [less ▲]

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See detailDominant amphipods of Posidonia oceanica seagrass meadows display considerable trophic diversity
Michel, Loïc ULg; Dauby, Patrick ULg; Gobert, Sylvie ULg et al

in Marine Ecology (in press)

Gut content examination and trophic markers (fatty acids, stables isotopes of C and N) were combined to delineate the diet of the dominant species of amphipods from Mediterranean Posidonia oceanica ... [more ▼]

Gut content examination and trophic markers (fatty acids, stables isotopes of C and N) were combined to delineate the diet of the dominant species of amphipods from Mediterranean Posidonia oceanica seagrass meadows and to highlight trophic diversity among this community. Our results indicate that, although all dominant species heavily relied on macroalgal epiphytes, considerable interspecific dietary differences existed. Carbon stable isotope ratios notably showed that some of the amphipod species favored grazing on epiphytes from leaves or litter fragments (Apherusa chiereghinii, Aora spinicornis, Gammarus aequicauda), while others like Dexamine spiniventris preferred epiphytes from rhizomes. The remaining amphipods (Caprella acanthifera, Ampithoe helleri and Gammarella fucicola) readily consumed both groups. In addition, SIAR modeling suggested that most species had a mixed diet, and relied on several food items. Fatty acid analysis and gut contents revealed that contribution of microepiphytic diatoms and of benthic and suspended particulate organic matter to the diet of amphipods were anecdotal. None of the examined species seemed to graze on their seagrass host (low 18:2(n-6) and 18:3(n-3) fatty acids contents), but G. aequicauda partly relied on seagrass leaf detritus, as demonstrated by the lesser 13C-depletion of their tissues. Overall, our findings suggest that amphipods, because of their importance in transfers of organic matter from primary producers and detritus to higher rank consumers, are key-items in P. oceanica associated food webs. [less ▲]

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See detailLetter to the Editor.
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Seminars in arthritis and rheumatism (in press)

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See detailRestorative detention or ‘work on self’? Two accounts of a Belgian prison policy
Dubois, Christophe ULg; Vrancken, Didier ULg

in Ethnography (in press)

Besides being known for population overcrowding, prison staff strikes, and prisoner suicides or escapes, which are frequently reported by the press, prison might also be a place for rare innovative ... [more ▼]

Besides being known for population overcrowding, prison staff strikes, and prisoner suicides or escapes, which are frequently reported by the press, prison might also be a place for rare innovative projects. One such project can be seen in a penitentiary policy initiated in Belgium in 2000 aimed at re-shaping the culture of detention towards a culture of ‘restorative justice’. What can be said of this attempt at introducing the concepts of victim, restoration, responsibilization, sensitizing and awareness within prison walls? The present article proposes an illustrative and interpretive account of this prison policy. Rather than restoring the broken victim-offender relationship, its implementation has something to do with detainees working on their ‘self’. [less ▲]

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See detailLe Laboratoire d’Analyse statistique des langues anciennes : cinquante années de recherches
Longrée, Dominique ULg

in Etudes Classiques (Namur, Belgium) (in press)

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See detailCT SCAN FEATURES OF PRESUMPTIVE HAEMORRHAGIC STROKE IN A DOG WITH CUSHING’S DISEASE
Liotta, Annalisa Pia ULg; Cavrenne, Romain; Peeters, Dominique ULg et al

in Case reports in Veterinary Medicine (in press)

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailRôle et langue de Tchantchès dans les représentations en castelets des romans de chevalerie : le cas des Quatre fils Aymon
Baiwir, Esther ULg; Impe, Anaëlle

in Enquêtes du Musée de la Vie Wallonne (in press)

Pourquoi et dans quelle mesure les montreurs de marionnettes liégeoises font-ils intervenir Tchantchès aux côtés des grands chevaliers médiévaux, dont les aventures constituent une part importante du ... [more ▼]

Pourquoi et dans quelle mesure les montreurs de marionnettes liégeoises font-ils intervenir Tchantchès aux côtés des grands chevaliers médiévaux, dont les aventures constituent une part importante du répertoire liégeois ? Quels sont ses moyens d'action, mais également ses modes d'expression ? Divers registres de langue apparaissent au fil des spectacles ; quels sont ceux prêtés à notre héros ? Et surtout, ce rôle et cette langue ont-ils évolué au fil du temps ? C’est à ces quelques questions que nous tentons de répondre, en observant les différentes interventions de Tchantchès dans les réécritures des aventures des quatre fils Aymon, l’une des œuvres les plus anciennes et les plus fréquemment jouées dans les théâtres liégeois dévolus aux comédiens de bois. [less ▲]

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See detailOccurrence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary, Argentina, and their mid-distance movements along the Northeast Patagonian coast
Failla, Mauricio; Seijas, Veronica; Vermeulen, Els ULg

in Latin American Journal of Aquatic Mammals (in press)

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data ... [more ▼]

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data on the dolphin’s activity patterns were gathered via an Ad Libitum focal group sampling mode accompanying dorsal fin images taken for identification and re-identification of individuals. A total effort of 188 h resulted in 58 h of positive observation of 124 dolphin groups (sightings per unit effort (SPUE) = 0.66 groups/h). Data analysis showed two main activity states for the observed groups, travelling (65%) and foraging (26%). The remaining 9% of the groups were involved in other activity states. The photo-identification effort, which started opportunistically in 2006, resulted in a catalogue of 21 individual dolphins, with a total mean re-identification rate of 9 days (max = 24 days). When comparing these pictures to the existing catalogue of Bahía San Antonio (approximately 200 km west from the study area) dorsal fins of 20 individuals could be positively matched and most (n = 17) could be subsequently re-identified in both areas, indicating their long distance movements along the North Patagonian coast during the austral autumn months. This season coincides with the lowest amount of feeding activity observed in Bahía San Antonio. This study suggests that bottlenose dolphins enter RNE, mainly during autumn, to forage. It appears that the search for food resources may be the trigger for their movement patterns along the North Patagonian coast during this season, at least for certain individuals. More research is needed to accurately confirm this hypothesis. [less ▲]

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See detailCOMMENT JE TRAITE ... L’arrêt cardio-respiratoire extrahospitalier : la fenêtre du centraliste 112
STIPULANTE, Samuel ULg; ZANDONA, Régine; EL-FASSI, Mehdi ULg et al

in Revue Médicale de Liège (in press), 69

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See detailPrévention et promotion de la santé : quels modèles pour soutenir l’évolution des pratiques en soins de santé primaires ?
Vanmeerbeek, Marc ULg; Mathonet, Julien; Miermans, Marie-Christine ULg et al

in Presse Médicale (in press)

Objectives Published operating models about preventive health care and health promotion in primary care were sought with the aim of 1) compiling a functional inventory; and 2) to formulate working ... [more ▼]

Objectives Published operating models about preventive health care and health promotion in primary care were sought with the aim of 1) compiling a functional inventory; and 2) to formulate working hypotheses for the improvement of clinical practice towards more efficiency and more equity. Methods Narrative literature review, using keywords related to the various prevention classes, health promotion, primary care, practice models and health care delivery. The diversity of models led to a multi-criteria analysis. Results Twelve models were selected. Their characteristics were unevenly distributed. The models, whose authors announce that they apply to prevention, mainly describe approaches that focus on individuals within physician-patient relationship, and take into account practice organization. Some socio ecological and systems models illustrate health promotion: educational practice, group- or population-based targets, community environment and social determinants of health. There is little room for patients in elaborating the models, as they have little role in health care systems. The definitions of prevention, health promotion and patient education greatly differ from one model to another. Discussion Little is known about practical implementation of the models; assessment data are scarce. Some elements valued by health promotion could be integrated to health care: empowerment of citizens, addressing community environment; increased involvement in local health professionals’ networks; integration of individual and collective approaches within the same health care facilities to address simultaneously individual customization, efficiency and equity objectives. Conclusion These developments may call for adaptation in vocational training and continuous professional development: communication skills, awareness to public health concepts, and early and longitudinal exposure to community-based learning experiences for students. [less ▲]

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See detailFirst report of isolation and molecular characterization of bubaline herpesvirus 1 (BuHV1) from Argentinean water buffaloes
Maidana, Silvina; Konrad, José; Craig, Maria et al

in Archives of Virology (in press)

Herpesviruses have mainly co-evolved with their hosts for millions of years. However, bovine herpesvirus 1 (BoHV1) and related ruminant alphaherpesviruses have been reported to cross the species barrier ... [more ▼]

Herpesviruses have mainly co-evolved with their hosts for millions of years. However, bovine herpesvirus 1 (BoHV1) and related ruminant alphaherpesviruses have been reported to cross the species barrier. Bubaline herpesvirus 1 (BuHV1) is an alphaherpesvirus closely related to BoHV1 and BoHV5. According to the serological cross-relationships between ruminant alphaherpesviruses, several surveys have studied the occurrence of BoHV1-related virus infection in wild and domestic ruminant species. Recent studies in Argentina showed an increase in serological prevalence against BoHV1 related viruses in water buffaloes (Bubalus bubalis) population. The aim of this study was to investigate the presence of related ruminant alphaherpesvirus in the Argentinean water buffalo population. BuHV1 was successfully isolated from 5 out of 225 buffaloes analyzed. One isolate was obtained from nasal secretions, and the others were from vaginal swabs. The buffaloes belonged to four different farms located in northeastern Argentina. The isolates were characterized as alphaherpesvirus by direct immunofluorescence using FITC-anti-BoHV1 IgG. Restriction analysis performed with BamHI and BstEII on the complete genome showed differences between the isolates and those from BoHV1 and BoHV5 subtypes. Phylogenetic analysis on both UL27 and US6 showed similarity in tree topology. While three of the isolates grouped together with sequences of BoHV5, two other isolates clustered separately. Genetic analysis of eight concatenated sequences from all isolates and references strains showed high nucleotide sequence identity between BuHV1 and BoHV5. While three of the isolates clustered together with the BoHV5 reference strain, the last two isolates were closely related to an Australian BuHV1 strain. To our knowledge, this is the first report on the isolation and molecular characterization of BuHV1 in South America. Phylogenetic analysis suggested that two different BuHV1 lineages circulate in the Argentinean water buffalo population. [less ▲]

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