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See detailLes Fumistes wallons, un collectif en figuration
Saint-Amand, Denis ULg

in Textyles : Revue des Lettres Belges de Langue Française (in press)

Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert ... [more ▼]

Cet article propose l’analyse d’un cas particulier et très peu étudié de mise en scène de la vie collective en se fondant sur le texte à clef Les Fumistes wallons signé L. Hemma (pseudonyme d’Albert Mockel). On y montre comment, en tant qu’entrée en littérature, le texte de Mockel se donne à voir comme un positionnement singulier vis-à-vis de l’espace littéraire, dont l’auteur aborde d’emblée le fonctionnement en le raillant. [less ▲]

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See detailStroboscopic phenomena in superconductors with dynamic pinning landscape
Jelic, Zeljko ULg; Milosevic, Milorad; Van de Vondel, Joris et al

in Scientific Reports (in press)

Introducing artificial pinning centers is a well established strategy to trap quantum vortices and increase the maximal magnetic field and applied electric current that a superconductor can sustain ... [more ▼]

Introducing artificial pinning centers is a well established strategy to trap quantum vortices and increase the maximal magnetic field and applied electric current that a superconductor can sustain without dissipation. In case of spatially periodic pinning, a clear enhancement of the superconducting critical current arises when commensurability between the vortex configurations and the pinning landscape occurs. With recent achievements in (ultrafast) optics and nanoengineered plasmonics it has become possible to exploit the interaction of light with superconductivity, and create not only spatially periodic imprints on the superconducting condensate, but also temporally periodic ones. Here we show that in the latter case, temporal matching phenomena develop, caused by stroboscopic commensurability between the characteristic frequency of the vortex motion under applied current and the frequency of the dynamic pinning. The matching resonances persist in a broad parameter space, including magnetic field, driving current, or material purity, giving rise to unusual features such as externally variable resistance/impedance and Shapiro steps in current-voltage characteristics. All features are tunable by the frequency of the dynamic pinning landscape. These findings open further exploration avenues for using flashing, spatially engineered, and/or mobile excitations on superconductors, permitting us to achieve advanced functionalities. [less ▲]

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See detailGlycine receptors control the generation of projection neurons in the developing cerebral cortex
Avila, Ariel; Vidal, P.M.; Tielens, Sylvia ULg et al

in Cell Death & Differentiation (in press)

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See detailImaginer-lire le Capital
Pieron, Julien ULg

in Cahiers d'Etudes Germaniques (in press)

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See detailPractical management of Chronic Myeloid Leukemia in Belgium
Benghiat, FS.; Beguin, Yves ULg; Dessars, B. et al

in Belgian Journal of Hematology (in press)

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]

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See detailLate Pleistocene molecular dating of past population fragmentation and demographic changes in African rain forest tree species supports the forest refuge hypothesis
Duminil, Jérôme; Mona, Stefano; Mardulyn, Patrick et al

in Journal of Biogeography (in press)

Aim : Phylogeographical signatures of past population fragmentation and demographic change have been reported in several African rain forest trees. These signatures have usually been interpreted in the ... [more ▼]

Aim : Phylogeographical signatures of past population fragmentation and demographic change have been reported in several African rain forest trees. These signatures have usually been interpreted in the light of the Pleistocene forest refuge hypothesis, although dating these events has remained impracticable because of inadequate genetic markers. We assess the timing of interspecific and intraspecific genetic differentiation and demographic changes within two rain forest Erythrophleum tree species (Fabaceae: Caesalpinioideae). Location : Tropical forests of Upper Guinea (West Africa) and Lower Guinea (Atlantic Central Africa). Methods : Six single-copy nuclear genes were used to characterize the phylogeographical patterns of the parapatric sister species Erythrophleum suaveolens (characteristic of semi-deciduous or gallery forests) and Erythrophleum ivorense (characteristic of evergreen forests). The number of gene pools within each species was determined and the timings of their divergence and past demographic changes were estimated using Bayesian-based coalescent approaches. Results : Three geographically separated gene pools were identified within E. suaveolens, and a single gene pool was inferred in E. ivorense. All gene pools show signatures of demographic bottlenecks concomitant with the last glacial period (c. 120–12 ka). Species-tree inferences show that the two species diverged c. 600 ka, whereas the divergence between E. suaveolens gene pools was dated to the late Pleistocene (first divergence c. 120 ka, second c. 60 ka). Main conclusions : (1) Molecular dating of demographic changes of two African tropical forest tree species is consistent with the Pleistocene forest refuge hypothesis. (2) Tree species from Guinean evergreen tropical forests might have been less affected by past climate change than semi-deciduous species. (3) Our phylogeographical data support a recent date (Holocene) of the last opening of the Dahomey Gap. [less ▲]

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See detailCompte rendu de l'ouvrage de Frédéric MARCHESANI, Sur les traces des anciens "pays" de Wallonie
George, Philippe ULg

in Trésor de Liège. Bulletin trimestriel (in press)

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See detailContribution of distribution network control to voltage stability: A case study
Aristidou, Petros ULg; Valverde, Gustavo; Van Cutsem, Thierry ULg

in IEEE Transactions on Smart Grid (in press)

A case study dealing with long-term voltage instability in systems hosting active distribution networks is reported in this paper. It anticipates future situations with high penetration of dispersed ... [more ▼]

A case study dealing with long-term voltage instability in systems hosting active distribution networks is reported in this paper. It anticipates future situations with high penetration of dispersed generation, where the latter are used to keep distribution voltages within desired limits, in complement to load tap changers. The interactions between transmission and active distribution networks are investigated on a 3108-bus test system. It involves transmission grid, large generators, and forty distribution networks, each with dispersed generation steered by a controller inspired of model predictive control. The reported simulations show the impact of distribution network voltage restoration as well as the benefit of load voltage reduction actuated by the dispersed generators. [less ▲]

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See detailInternal encoding style and schizotypy: towards a conceptually-driven account of positive symptoms
Belayachi, Sanaa ULg; Laloyaux, Julien ULg; Laroi, Frank ULg et al

in Journal of Personality Disorders (in press)

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven ... [more ▼]

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven and conceptually-driven processing. A chronic imbalance between these two sources of stimulus encoding is likely to be maladaptive and could underlie cognitive and behavioral disturbances similar to that observed in schizotypy, especially if the balance is tipped too far towards conceptually-driven processing (i.e., Internal encoding style). This study aimed to examine the relationships between encoding style and various dimensions of schizotypy, by using a questionnaire that evaluates the extent to which pre-existing schemata (versus cues from the outside world) affect encoding processes. Consistent with previous findings, our results revealed that both Cognitive-Perceptual and Disorganization dimensions were related to an internal mode of encoding, suggesting that individuals with these features may be characterized by a disposition to biases at early stages of encoding. [less ▲]

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See detailLeidenfrost drops: effect of gravity
Maquet, Laurent ULg; Brandenbourger, Martin ULg; Sobac, Benjamin et al

in Europhysics Letters [=EPL] (in press)

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See detailDouble hydrophilic polyphosphoester containing copolymers as efficient templating agents for calcium carbonate microparticles
Ergül, Zeynep ULg; Debuigne, Antoine ULg; Calvignac, Brice et al

in Journal of Materials Chemistry B (in press)

The use of calcium carbonate (CaCO3) microparticles is becoming more and more attractive in many fields especially in biomedical applications in which the fine tuning of the size, morphology and ... [more ▼]

The use of calcium carbonate (CaCO3) microparticles is becoming more and more attractive in many fields especially in biomedical applications in which the fine tuning of the size, morphology and crystalline form of the CaCO3 particles is crucial. Although some structuring compounds, like hyaluronic acid, give satisfying results, the control of the particle structure still has to be improved. To this end, we evaluated the CaCO3 structuring capacity of novel well-defined double hydrophilic block copolymers composed of poly(ethylene oxide) and a polyphosphoester segment with an affinity for calcium like poly(phosphotriester)s bearing pendent carboxylic acids or poly(phosphodiester)s with a negatively charged oxygen atom on each repeating monomer unit. These copolymers were synthesized by a combination of organocatalyzed ring opening polymerization, thiol–yne click chemistry and protection/deprotection methods. The formulation of CaCO3 particles was then performed in the presence of these block copolymers (i) by the classical chemical pathway involving CaCl2 and Na2CO3 and (ii) by a process based on supercritical carbon dioxide (scCO2) technology in which CO32− ions are generated in aqueous media and react with Ca2+ ions. Porous CaCO3 microspheres composed of vaterite nanocrystals were obtained. Moreover, a clear dependence of the particle size on the structure of the templating agent was emphasized. In this work, we show that the use of the supercritical process and the substitution of hyaluronic acid for a carboxylic acid containing copolymer decreases the size of the CaCO3 particles by a factor of 6 (∼1.5 μm) while preventing their aggregation. [less ▲]

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See detailDeveloping biodiversity indicators on a stakeholders' opinions basis: the gypsum industry Key Performance Indicators framework.
Pitz, Carline ULg; Mahy, Grégory ULg; Vermeulen, Cédric ULg et al

in Environmental Science and Pollution Research (in press)

Aims: To establish a common Key Performance Indicators (KPIs) framework for reporting about the gypsum industry biodiversity at the European level. Methods: In order to integrate different opinions and to ... [more ▼]

Aims: To establish a common Key Performance Indicators (KPIs) framework for reporting about the gypsum industry biodiversity at the European level. Methods: In order to integrate different opinions and to reach a consensus framework, an original participatory process approach has been developed among different stakeholder groups: Eurogypsum, European and regional authorities, universities scientists, consulting offices, European and regional associations for the conservation of nature and the extractive industry. The strategy is developed around four main steps: (i) building of a maximum set of indicators to be submitted to stakeholders based on the literature (Focus Group method); (ii) evaluating the consensus about indicators through a policy Delphi survey aiming at the prioritization of indicator classes using the Analytic Hierarchy Process method (AHP) and of individual indicators; (iii) testing acceptability and feasibility through analysis of Environmental Impact Assessments (EIAs) and visits to three European quarries; (iv) Eurogypsum final decision and communication. Results: The resulting framework contains a set of 11 indicators considered the most suitable for all the stakeholders. Conclusions: Our KPIs respond to European legislation and strategies for biodiversity. The framework aims at improving sustainability in quarries and at helping to manage biodiversity as well as to allow the creation of coherent reporting systems. The final goal is to allow for the definition of the actual biodiversity status of gypsum quarries and allow for enhancing it. The framework is adaptable to the local context of each gypsum quarry. [less ▲]

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See detailThe “Belgian Tetris”: Assessing the political impact of metaphors on citizens’ representations of Belgian federalism
Perrez, Julien ULg; Reuchamps, Min

in Metaphor and the Social World (in press)

Based on the idea that metaphors do not only reflect the perceived reality, but also function as cues through which citizens come to understand complex political processes, the aim of this study is to ... [more ▼]

Based on the idea that metaphors do not only reflect the perceived reality, but also function as cues through which citizens come to understand complex political processes, the aim of this study is to look at how specific metaphors might impact on the citizens' framing of Belgian federalism. To measure the impact of metaphors on the citizens' political representations, we conducted an experiment among 493 citizens based on an article published in the newspaper Le Soir in which Belgian federalism was compared to a Tetris game in both a text and an image. The participants were distributed into four experimental conditions according to the type of input they had been exposed to (text and image, text only, image only, no input) and were asked to perform a free description task. The productions of the participants were analyzed using keyword analyses and content analyses. The results suggest that the participants who had been exposed to the experimental text tend to differently frame their perception of Belgian federalism. These results show that reading the text, more than looking at the image, has an impact on the representations of the citizens but that this impact is short-lived. [less ▲]

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See detailSiting Controversies Analysis: Framework and Method for Questioning the Procedure
Rossignol, Nicolas ULg; Parotte, Céline ULg; Joris, Geoffrey ULg et al

in Journal of Risk Research (in press)

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]

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See detailThe importance of the tumor microenvironment in the therapeutic management of cancer
Pottier, Charles ULg; Wheatherspoon, Alodie; RONCARATI, Patrick ULg et al

in Expert Review of Anticancer Therapy (in press)

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See detailBiochemical characterization of the oil of durum wheat germ (Tunisian variety)
Kammoun, Maroua; Rassâa, Neila; Mejri-Gaïda, Myriam et al

in Journal of New Sciences (in press)

The wheat germ oil may constitute an alternative to the misuse of this cereal grain resource. The Tunisian exploitation is limited, at present, in the human and animal feed in the grain form, straw or ... [more ▼]

The wheat germ oil may constitute an alternative to the misuse of this cereal grain resource. The Tunisian exploitation is limited, at present, in the human and animal feed in the grain form, straw or some transformed products. For the purpose of characterization, the wheat germ oil has been extracted by Soxhlet apparatus from a Tunisian variety of durum wheat (Maali) based on the hexane as a solvent. An analysis by gas chromatography (GC) was then performed to identify and quantify the fatty acids of the oil. Then, the oil has submitted to a second chromatography analysis in liquid phase (HPLC) to quantify the tocopherols. The most important fatty acids constituting have been the two polyunsaturated acids linoleic acid C18:2 (OMEGA 6) and the gamma acid- linoleic C18:3 : 58.24 % and 4.19 % respectively; and the acid monounsaturated oleic acid C18:1 ( 24.49 %) but also some saturated acid: palmitic acid C16:0 with ( 19.50 % ), and the stearic acid C18:0 (1.29%). For this variety of Tunisian durum wheat, the wheat germ oil contains, in addition, 80.27 mg / 100g of α- tocopherols (vitamin E). The wheat germ oil extracted from the Tunisian variety 'Maali' has proved rich in vitamin E and omega-6 ; a better valorisation on the nutritional or pharmaceutical plan is to this title recommended. [less ▲]

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See detailReflexive Loops on Scaling issues in Landscape Quality Assessment
Schmitz, Serge ULg; Vanderheyden, Vincent ULg

in Land Use Policy (in press)

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See detailExploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for dating
Guibert, Pierre; Urbanova, Petra; Blain, Sophie ULg et al

in Radiation Measurements (in press)

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]

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See detailDe Rome à Wilderen : Alexandre Ier et Raoul de Saint-Trond
Schmidt, Kevin ULg

in Revue Belge de Philologie et d'Histoire (in press)

While Rudolf, the abbot of Sint-Truiden (1108-1138) was forced to abandon his monastery in 1121 after having opposed the claim to power of the future prince-bishop of Liège, Alexandre I (1128-1135), both ... [more ▼]

While Rudolf, the abbot of Sint-Truiden (1108-1138) was forced to abandon his monastery in 1121 after having opposed the claim to power of the future prince-bishop of Liège, Alexandre I (1128-1135), both men hastily set out for Rome on the eve of 1129, in order to meet Pope Honorius the Second. The Gesta abbatum Trudonensium have preserved this colorful account of the perilous circumstances under which they crossed the Great St. Bernard Pass together in full winter. Starting from this particular anecdote, the document, which recounts the evolving personal relationship between the bishop of Liège, Alexandre I and abbot Rudolf of Sint-Truiden, returns to the circumstances surrounding this surprising rapprochement, which came to pass against all expectations. It seeks to demonstrate that Rudolf of Sint-Truiden’s motivations to accompany his former enemy to Italy were political rather than spiritual. [less ▲]

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See detailCongenital jaundice in bovine aborted fetuses: an emerging syndrome in Southern Belgium
Delooz; Mori, M; Petitjean, T et al

in Transboundary and Emerging Diseases (in press)

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See detailDélinquance des adolescents et maturation pubertaire analysées au travers du timing pubertaire perçu
Glowacz, Fabienne ULg; Bourguignon, Jean-Pierre ULg

in Annales Médico-Psychologiques (in press)

The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between ... [more ▼]

The impact of pubertal development on the psychological and social functioning of the teenager arouses a particular interest; the most recent research shows the existence of complex relationships between pubertal development and the manifestation of internalized and externalized disorders. Two predominant hypothesis are used for explain influence of pubertal timing on problem behaviors : the maturational deviance theory and the stage termination (early timing) theory. The deviance theory claims that the borderline or abnormal pubertal timing, whether early or late, causes difficulties for adolescent adaptation. The early timing theory suggests that early pubertal timing and the consequent early physical maturation put adolescents at greater risk of adjustment problems because early pubertal maturation interferes with normal progression through the developmental tasks of adolescence. Our study is interested specifically in the links between delinquency during adolescence and pubertal maturation in a population of 141 boys aged between 12 and 18. We measured the pubertal variable starting from the perceived pubertal timing (PPT), which evaluates the teenagers' perception of their pubertal maturation, compared with that of their peers, to understand its impact on various dimensions of the functioning of teenagers: the self-perception (scale of Harter), aggressiveness (scale of Buss and Perry), association with peers and self-reported delinquency (attacks on property and individuals). We began with univariate analyses in order to determine the variables associated with early or late pubertal timing through comparison of scores obtained in those subjects with reference to average maturers. Subsequently, multivariate analyses were used in an attempt to sort out which among the studied factors could be predictor or a determinant of delinquency in relation to pubertal timing. Therefore, stepwise multiple regression analysis was performed. Statistical analyses were run with the SAS software, version 9.1.Our results support the thesis of precocity, the teenagers with an advanced PPT present scores of delinquency and aggressiveness significantly higher than teenagers with a standard PPT. However, the sub-group of teenagers with delayed PPT present raw scores of self-revealed delinquency which are higher than those of teenagers with a standard PPT. These teenagers can be characterized by a significantly higher hostility than the teenagers with a standard PPT. This cognitive dimension of aggressiveness, as evaluated by Buss and Perry, characterizes the functioning of the teenagers with the delayed PPT, who also present poorer self-esteem and dissatisfaction with their physical appearance. On the basis of this assessment, an analysis of multiple regression within each type of PPT aimed at identifying the variables likely to explain the delinquency of teenagers according to their PPT. The results show that the physical factor of aggressiveness is common to the three types of PPT. It is associated with the affiliation with delinquent peers for those teenagers with advanced and normal PPT, whereas for those teenagers with delayed PPT, it interacts with the factor of hostility, which is specific to them. Association with delinquent peers recognized as a major risk factor and predictive for the self-revealed delinquency of teenagers in general does not intervene for these boys who perceive their pubertal development late, compared to the others. The delinquency of teenagers with a delayed PPT cannot be explained by the factors that are considered in the general population, their social functioning and the socialization of these teenagers with delayed puberty is different from that of the other teenagers, as is their implication in delinquency, which is not explained by a kind of socialization with delinquent peers. These results confirm the importance of integrating the puberty variable into research on delinquency, but also at the level of intervention. [less ▲]

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See detailSurvivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétation
Veymiers, Richard ULg

in Anabases : Traditions et Réception de l'Antiquité (in press)

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See detailClinical sentinel surveillance of equine West Nile fever, Spain
Saegerman, Claude ULg; Alba-Casals, A; Garcia-Bocanegra, I et al

in Transboundary and Emerging Diseases (in press)

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See detailAn analysis of potential resistance of the phytophagous mite, Tetranychus urticae (Tetranychidae) to four botanical pesticides
Attia, Sabrine; Lebdi, KL; Heuskin, Stéphanie ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailRaman characterization of the UV-protective pigment gloeocapsin and its role in the survival of cyanobacteria
Storme, Jean-Yves ULg; Golubic, Stjepko; Wilmotte, Annick ULg et al

in Astrobiology (in press)

Extracellular UV-screening pigments gloeocapsin and scytonemin present in the EPS envelopes of extremophile cyanobacteria of freshwater and marine environments were studied by Raman spectroscopy and ... [more ▼]

Extracellular UV-screening pigments gloeocapsin and scytonemin present in the EPS envelopes of extremophile cyanobacteria of freshwater and marine environments were studied by Raman spectroscopy and compared to their intracellular photosynthetic pigments. This Raman spectral analysis of the extracellular pigment gloeocapsin showed that it shared Raman spectral signatures with parietin, a radiation-protective pigment known in lichens. The UV-light spectra also showed similarities. Gloeocapsin occurs in some cyanobacterial species, mostly with exclusion of scytonemin, indicating that these pigments have evolved in cyanobacteria as separate protective strategies. Both gloeocapsin and scytonemin are widely and species-specifically distributed in different cyanobacterial genera and families. The widespread occurrence of these pigments may suggest an early origin, while their detection by Raman Spectroscopy makes them potential biosignatures for cyanobacteria in the fossil record and demonstrates the usefulness of non-destructive Raman spectroscopy analyses for the search of complex organics, including possible photosynthetic pigments, if preservable in early Earth and extraterrestrial samples. [less ▲]

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See detailAmphibians forego aquatic life in response to alien fish introduction
Winandy, Laurane ULg; Darnet, Elodie; Denoël, Mathieu ULg

in Animal Behaviour (in press)

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See detailExperimental Tests and Numerical Modelling on Slender Steel Columns at High Temperatures
Franssen, Jean-Marc ULg; Zhao, Bin; Gernay, Thomas ULg

in Journal of Structural Fire Engineering (in press)

This paper is about a series of experimental fire tests on eight full scale steel columns made of slender I shaped class 4 sections. Six columns were made of welded sections (some prismatic and some ... [more ▼]

This paper is about a series of experimental fire tests on eight full scale steel columns made of slender I shaped class 4 sections. Six columns were made of welded sections (some prismatic and some tapered members) and two columns were made of hot rolled sections. The nominal length of the columns was 2.7 meters with the whole length being heated. The load was applied at ambient temperature after which the temperature was increased under constant load. The load was applied concentrically on some tests and with an eccentricity in other tests. Heating was applied by electrical resistances enclosed in ceramic pads. Numerical simulations were performed with the software SAFIR® using shell elements. The paper presents the results obtained in terms of failure mode and ultimate temperature, in the experimental tests and in the numerical simulations. [less ▲]

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See detailLa question du diagnostic en psychiatrie infanto-juvénile
de Becker, Emmanuel; François, Anne; Kinoo, Philippe et al

in Psychiatrie de l'Enfant (La) (in press)

Dans le vaste champ de l’aide et des soins à l’égard de l’enfant et de l’adolescent, les questions liées au diagnostic transcendent souvent les aspects de prises en charge et de liens thérapeutiques ainsi ... [more ▼]

Dans le vaste champ de l’aide et des soins à l’égard de l’enfant et de l’adolescent, les questions liées au diagnostic transcendent souvent les aspects de prises en charge et de liens thérapeutiques ainsi que les multiples échanges entre professionnels concernés. Le diagnostic pédopsychiatrique est un processus dynamique, modifiable et momentané, les organisations pathologiques étant pour la plupart en transformation permanente. De manière spécifique et en fonction du processus développemental, la thématique du diagnostic en pédopsychiatrie renvoie plus à la question du risque évolutif qu’à la question d’un état pathologique en soi. Les aspects de la continuité des troubles mentaux de l’enfance à l’âge adulte représentent en effet un véritable enjeu développemental. Deux points de vue s’opposent dans la littérature. Le premier, en lien avec un prédéterminisme, estime que les trajectoires sont toutes tracées, l’incertitude reposant dans le diagnostic ; concrètement, il s’agit de repérer de manière précoce des individus à risque parce qu’ils sont porteurs d’un trouble qu’il faut traiter. Le second point de vue considère que les trajectoires ne sont pas déterminées mais sont en réécriture permanente ; ici, le risque ne se situe plus au niveau du diagnostic mais du pronostic, dans un souci de prévention et non de prédiction. L’article propose les réflexions de quatre cliniciens psychiatres infanto-juvéniles sur cette thématique, à la lumière de leur pratique et de leurs échanges. [less ▲]

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See detailClinical pharmacology of antifungal agents to overcome drug resistance in pediatric patients
STERGIOPOULOU, Theodouli ULg; Walsh, Thomas J.

in Expert opinion on pharmacotherapy (in press), 16(2), 213-26

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological ... [more ▼]

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERED: This paper reviews the mechanisms of resistance of different classes of antifungal agents and the current understanding of pediatric antifungal pharmacology for overcoming antifungal resistance in children based on laboratory and clinical studies in the English literature. The therapeutic choices against fungal pathogens with intrinsic or acquired resistance are further reviewed. EXPERT OPINION: There is a paucity of data in the pediatric population regarding the epidemiology of the resistant organisms to different antifungal agents. It is also unknown if there are more prevalent molecular mechanisms that promote antifungal resistance. Selection and dosages of the most effective antifungal agent for overcoming the antifungal resistance is crucial. However, there are limited studies guiding the optimal dosage and duration of treatment for management of emergent antifungal resistance. Further studies are warranted to elucidate the optimal pharmacology of the current antifungal agents against resistant organisms and to advance the development of new antifungal agents. [less ▲]

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See detailLes recettes de l’Autre. De la transmission des savoirs (et savoir-faire) féminins en contexte migratoire.
Mescoli, Elsa ULg

in Hommes & Migrations (in press)

La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont ... [more ▼]

La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont confrontés à des styles alimentaires différents. Ces recherches s’engagent alors à vérifier dans quelle mesure cette rencontre défie l’identité individuelle (Cardona, 2004; Crenn, 2004; Spiro, 1955) et quelles pratiques elle engage afin de la préserver (Hage, 1997; Beyers, 2008; Diner and Diner, 2009). L’attention est ainsi portée au contexte domestique dans lequel les familles issues de la migration préparent leurs repas et, potentiellement, définissent leur appartenance culturelle. Une deuxième direction entreprise par ces études, concerne par contre l’espace public : par exemple, les ainsi dits « restaurants ethniques » font l’objet de nombreuses recherches qui visent cette fois à analyser la consommation de l’ « exotique » de la part des membres de la population majoritaire (Hassoun & Raulin, 1995; Régnier, 2005). Ces deux dimensions principales sont rarement abordées dans leur superposition, fait qui laisse dans l’ombre des dynamiques pareillement pertinentes. Notamment, nous pourrions relever les enjeux liés à la préparation de nourriture conçue comme pratique du quotidien destinée à être exportée en contexte non-domestique et offerte à des individus qui, non seulement ne font pas partie de la famille de ceux qui cuisinent, mais sont aussi associés à une appartenance culturelle différente. L’étude de ces enjeux amène à constater que la définition active de soi au travers de la pratique culinaire s’entremêle à la volonté d’en transmettre une image aux autres. En particulier, lorsqu’on adopte une perspective de genre et que l’on focalise l’attention sur les femmes migrantes, nous sommes amenés à noter comment un de ces savoir-faire qui constituent des potentiels dispositifs de domestication (Rogers, 1981) se transforme en instrument de visibilité, et ainsi de participation, dans l’espace public. Dans cet article, afin de mettre en évidence la complexité de ces dynamiques, je présenterai en clef comparative des exemples collectés dans le cadre de mes recherches autour du lien entre alimentation et migration. J’analyserai les pratiques culinaires exercées en contexte public d’un côté par un groupe de femmes marocaines résidentes en Italie, de l’autre par certaines femmes italiennes résidentes en Belgique. La comparaison des choix des femmes, faits en fonction des destinataires mais aussi en réponse aux différents contextes sociopolitiques dans lesquels certaines manifestations culinaires prennent la forme de « rencontres interculturelles », permettra de donner un aperçu sur la façon dont les femmes considérées s’assurent une place active dans l’espace vécu. Le texte sera illustré par des images collectées durant l’ethnographie. [less ▲]

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See detailUsing seismic inversions to obtain an indicator of internal mixing processes in main-sequence solar-like stars
Buldgen, Gaël ULg; Dupret, Marc-Antoine ULg; Reese, Daniel Roy

in Astronomy and Astrophysics (in press)

Context. Currently, seismic modelling is one of the best ways of building accurate stellar models, thereby providing accurate ages. However, current methods are affected by simplifying assumptions ... [more ▼]

Context. Currently, seismic modelling is one of the best ways of building accurate stellar models, thereby providing accurate ages. However, current methods are affected by simplifying assumptions concerning stellar mixing processes. In this context, providing new structural indicators that are less model-dependent and more sensitive to mixing processes is crucial. Aims. We wish to build a new indicator for core conditions (i.e. mixing processes and evolutionary stage) on the main sequence. This indicator tu should be more sensitive to structural differences and applicable to older stars than the indicator t presented in a previous paper. We also wish to analyse the importance of the number and type of modes for the inversion, as well as the impact of various constraints and levels of accuracy in the forward modelling process that is used to obtain reference models for the inversion. Methods. First, we present a method of obtaining new structural kernels in the context of asteroseismology. We then use these new kernels to build a new indicator of central conditions in stars, denoted tu, and test it for various effects including atomic diffusion, various initial helium abundances, and various metallicities, following the seismic inversion method presented in our previous paper. We then study the indicator’s accuracy for seven different pulsation spectra including those of 16CygA and 16CygB and analyse how it depends on the reference model by using different constraints and levels of accuracy for its selection Results. We observe that the inversion of the new indicator tu using the SOLA method provides a good diagnostic for additional mixing processes in central regions of stars. Its sensitivity allows us to test for diffusive processes and chemical composition mismatch. We also observe that using modes of degree 3 can improve the accuracy of the results, as well as using modes of low radial [less ▲]

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See detailSociologie de la communication politique
Devresse, Jenifer ULg

in Communication (in press)

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See detailLes croyances délétères des patients lombalgiques : revue narrative de la littérature
Demoulin, Christophe ULg; Roussel, Nathalie; Marty, Marc et al

in Revue Médicale de Liège (in press)

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See detailp-regularity of the p-adic valuation of the Fibonacci sequence
Medina, Luis; Rowland, Eric ULg

in The Fibonacci Quarterly (in press)

We show that the p-adic valuation of the sequence of Fibonacci numbers is a p-regular sequence for every prime p. For p≠2,5, we determine that the rank of this sequence is α(p)+1, where α(m) is the ... [more ▼]

We show that the p-adic valuation of the sequence of Fibonacci numbers is a p-regular sequence for every prime p. For p≠2,5, we determine that the rank of this sequence is α(p)+1, where α(m) is the restricted period length of the Fibonacci sequence modulo m. [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailPublication outcomes of the abstracts presented at the 2011 European Congress on Osteoporosis, Osteoarthritis and Musculo-Skeletal Diseases (ECCEO-IOF11) : A position paper of the European Society for Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculo-Skeletal Diseases (ESCEO) and the International Osteoporosis and Other Skeletal Diseases Foundation (IOF).
Rabenda, Véronique ULg; Bruyère, Olivier ULg; Cooper, Cyrus et al

in Archives of osteoporosis (in press)

The publication outcomes of the abstracts presented during the ECCEO-IOF 2011 reflect a high research productivity, support the robustness of the selection process conducted by the Scientific Advisory ... [more ▼]

The publication outcomes of the abstracts presented during the ECCEO-IOF 2011 reflect a high research productivity, support the robustness of the selection process conducted by the Scientific Advisory Committee and suggest that IOF-ESCEO WCO is successful in its mission to promote and disseminate research. BACKGROUND AND OBJECTIVE: The European (now World) Congress on Osteoporosis, Osteoarthritis and Musculo-Skeletal Diseases (IOF-ESCEO WCO, formerly ECCEO-IOF) is the largest worldwide event fully dedicated to the clinical, epidemiological, translational and economic aspects of bone, joint and muscle diseases. The role of the Scientific Advisory Committee is to select abstracts for oral communication or poster presentation based on a short summary of the research. The aim of the present survey was to determine the publication rate in international peer reviewed journals of abstracts accepted at the IOF-ESCEO WCO 2011 Meeting (formerly ECCEO-IOF11), the relationship, if any, between the presentation format of the abstract and its subsequent full publication and the impact factor of the journal in which research was published. RESULTS: Of 619 abstracts accepted at the 2011 ECCEO-IOF11 annual meeting, 45 were accepted for oral communication and 574 accepted for poster presentation. In the subsequent 3 years (2011-2014), 191 abstracts were published as a full-length manuscript (30.9 %). The publication rate was significantly higher for oral communications (75.6 %) than for poster presentations (27.4 %; p < 0.0001). Publications derived from oral communications were published in journals with a higher impact factor (8.3 +/- 10.1) than those arising from poster presentations (4.0 +/- 2.3; p < 0.0001), but there was no difference in the time to publication (OC 16.3 [IQR 8.4-23.3] months vs PP 11.3 [IQR 5.3-21.4]; p = 0.14). CONCLUSION: These results indicate a high research productivity and an appropriate selection of oral communication by the Scientific Advisory Committee of ESCEO-IOF. [less ▲]

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See detailUn type picard par-delà les frontières : le <nom jeté>
Baiwir, Esther ULg

in Dialectes de Wallonie (in press), 36

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See detailHuman Papillomavirus-related tumours of the oropharynx display a lower tumour hypoxia signature
Hanns, Elodie; Job, Sylvie; Coliat, Pierre et al

in Oral Oncology (in press)

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See detailEffects of Methylmercury on Harbour Seal Peripheral Blood Leucocytes In Vitro Studied by Electron Microscopy
Dupont, Aurélie; De Pauw-Gillet, Marie-Claire ULg; Schnitzler, Joseph ULg et al

in Archives of Environmental Contamination & Toxicology (in press)

Methylmercury MeHg is highly immunotoxic and can alter the health status of the harbour seal, Phoca vitulina, from the North Sea. To investigate the mechanism of MeHg-induced toxicity in harbour seal ... [more ▼]

Methylmercury MeHg is highly immunotoxic and can alter the health status of the harbour seal, Phoca vitulina, from the North Sea. To investigate the mechanism of MeHg-induced toxicity in harbour seal lymphocytes, ConA-stimulated peripheral blood leucocytes were exposed in vitro to sub-lethal concentrations of MeHgCl (0.2, 1 and 2 µM) for 72h, and then analysed for their viability and ultrastructure. After 72h of incubation, cells were counted with a propidium iodide staining technique, a metabolic MTS assay was performed, and cells exposed to 1 µM MeHgCl were observed by transmission electron microscopy (TEM). Alive cell numbers decreased with increased MeHgCl concentrations. In presence of ConA and 1µM of MeHgCl, TEM images revealed a higher frequency of apoptotic cells. Exposed cells displayed condensation of the chromatin at the nuclear membrane and mitochondrial damages. The results suggest that in vitro MeHgCl induced apoptosis in harbour seal lymphocytes through a mitochondrial pathway. [less ▲]

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See detailMyelofibrosis patients in Belgium: disease characteristics
Devos, Timothy; Zachée, Pierre; Bron, Domonique et al

in Acta Clinica Belgica (in press)

Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according ... [more ▼]

Objective: To date, only a small number of epidemiological studies on myelofibrosis have been performed. The current study aimed to characterize the myelofibrosis patient population in Belgium according to predefined disease parameters (diagnosis, risk categories, hemoglobin ,10 g/dl, spleen size, constitutional symptoms, platelet count, myeloblast count), with a view to obtaining a deeper understanding of the proportion of patients that may benefit from the novel myelofibrosis therapeutic strategies. Methods: A survey was used to collect data on prevalence and disease parameters on all myelofibrosis patients seen at each of 18 participating hematologic centers in 2011. Aggregated data from all centers were used for analysis. Analyses were descriptive and quantitative. Results: A total of 250 patients with myelofibrosis were captured; of these, 136 (54%) were male and 153 (61%) were over 65 years old. One hundred sixty-five (66%) of myelofibrosis patients had primary myelofibrosis and 85 (34%) had secondary myelofibrosis. One hundred ninety-three myelofibrosis patients (77%) had a palpable spleen. About a third of patients (34%) suffered from constitutional symptoms. Two hundred twenty-two (89%) myelofibrosis patients had platelet count§50 000/ml and 201 (80%) had platelet count §100 000/ml. Of 250 patients, 85 (34%) had a myeloblast count §1%. Six (2%) patients had undergone a splenectomy. Thirteen (5.2%) patients had undergone radiotherapy for splenomegaly. Conclusions: The results of this survey provide insight into the characteristics of the Belgian myelofibrosis population. They also suggest that a large proportion of these patients could stand to benefit from the therapies currently under development. [less ▲]

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See detailRisk assessment of soil compaction in the Walloon region in Belgium
D'Or, Dimitri; Destain, Marie-France ULg

in Mathematical Geosciences (in press)

It is well known that soil compaction affects root growth and disrupts the activity of soil microfauna and microorganisms, resulting in yield loss. With the more intensive use of heavy machines in ... [more ▼]

It is well known that soil compaction affects root growth and disrupts the activity of soil microfauna and microorganisms, resulting in yield loss. With the more intensive use of heavy machines in agriculture and forestry, the risk of soil compaction is increasing. In this study, precompression stress (Pc) was chosen as an indicator of the susceptibility of soils to compaction and was calculated using pedotransfer functions (PTFs). PTFs involve eight variables related to the hydraulic and mechanical behaviour of soils: organic matter content; bulk density; air capacity; available water capacity; non-plant available water capacity; saturated hydraulic conductivity; cohesion; and angle of internal friction. Combining these PTFs with geostatistics and Monte Carlo simulations, Pc maps were produced at the regional scale for Wallonia in Belgium, accompanied by uncertainty quantification maps. These maps were then used to produce compaction risk maps based on common scenarios. The results showed that the modal Pc map was coherent with the spatial distribution of the main variables, namely soil texture and organic matter content. The risk maps enabled areas with a compaction risk in both agricultural and forestry contexts to be identified. These maps could be useful in drawing up soil protection measures and policies. [less ▲]

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See detailNGOs and female circumcision in Egypt. An anthropological enquiry.
Mescoli, Elsa ULg

in Journal of the Anthropology of the Contemporary Middle East and Central Eurasia (in press)

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the ... [more ▼]

In 1994, during the International Conference on Population and Development convened by the United Nations in Cairo, a shocking video was shown, realized by an operator of CNN and depicting the circumcision of a ten-year-old child living in this very same city. Discourses around female circumcision were not new in Egypt and in the international community, but what was considered as a new episode of a recurrent scandal (not the last one indeed) led to enhance the "war against bad government"[1]. A war fought by means of ideological weapons produced by expert knowledges among which the medical and the feminist ones. The assignment of a value to the state of integrity of the female body and to the women freedom of choice, both designed according to Western canons, led to different actions to “save” Egyptian women. In this context, development agencies fosters a widespread representation of the victim, constituted by the woman mutilated body. Such representation is functional to put in place programs which do not guarantee a freedom of choice, but rather require adherence to another female model, one that defines the "modern" woman. My article, based on ethnographic experience, aims at highlighting the complexity of such dynamics and the role played by humanitarianism within them. Female body becomes the arena where local and international economic powers operate, disregarding a real understanding of the practice, its meanings and its eventual change. ________________________________________ [1] Foucault, Michel. La nascita della clinica. Il ruolo della medicina nella costituzione delle scienze umane, Einaudi, Torino 1969: 48. [less ▲]

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See detailEfficiency of delivery observed treatment in hemodialysis patients: the example of the native vitamin D therapy
DELANAYE, Pierre ULg; CAVALIER, Etienne ULg; Fafin, Coraline et al

in Journal of Nephrology (in press)

Introduction Adherence to therapy is a relevant challenge in chronic hemodialysis patients. The directly observed therapy (DOT) could be an effective method to increase adherence for specific therapies ... [more ▼]

Introduction Adherence to therapy is a relevant challenge in chronic hemodialysis patients. The directly observed therapy (DOT) could be an effective method to increase adherence for specific therapies. We aimed to study the performance of DOT versus home medication. We follow the impact of providing native vitamin D directly by the nurse after a dialysis session on the 25-hydroxyvitamin [25(OH)D] concentrations. Methods In this observational study, we included 38 dialysis patients treated by stable dosage of cholecalciferol. DOT was implemented in December 2010. We considered the concentrations of 25-OH vitamin D three times before (T1 = June 2010, T2 = July 2010 and T3 = September 2010) and three times after the modification of prescription (T4 = February 2011, T5 = March 2011 and T6 = April 2011). Results Median age was 72 [62; 79] years and 48 % were diabetics. Mean body mass index was 26 ± 5 kg/m2 and median dialysis vintage was 20 [8; 46] months. The patients were compared to themselves. Before DOT, median concentrations of 25(OH)D were 27 (14–36), 23 (17–31), 31 (22–38) ng/mL at T1, T2 and T3, respectively. When DOT was effective, the concentrations significantly increased to 34 (28–44), 35 (29–41), 39 (32–47) ng/mL at T4, T5 and T6, respectively. Before DOT, 19 patients (50 %) reached the target of 30 ng/mL. After DOT, 29 patients (76 %) reached the target concentration of 30 ng/ mL. Conclusions In hemodialysis patients, DOT is both simple and effective to increase the therapeutic impact to native vitamin D. [less ▲]

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See detailLa flexicurité revisitée : analyse qualitative interdisciplinaire du discours de travailleurs à l'aide d'un logiciel collaboratif »
Beuker, Laura ULg; DE CIA, Julie ULg; Dervaux, Amélie ULg et al

in Recherches Qualitatives (in press)

L’ambition de cet article est double : explorer les vertus de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire sur la flexicurité, et réaliser une revue de ... [more ▼]

L’ambition de cet article est double : explorer les vertus de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire sur la flexicurité, et réaliser une revue de littérature transversale à partir des problématiques concrètes que ce concept cristallise dans le vécu des travailleurs. La flexicurité constitue un oxymore qui prône la recherche d’un équilibre entre besoins de flexibilité et de sécurité sur le marché du travail. Cet équilibre est avant tout un objectif politique, mais il reste fragile aux yeux des acteurs concernés. En cherchant à croiser le regard analytique de trois disciplines – psychologie, gestion et sociologie –, nous avons recouru au logiciel Cassandre (Lejeune, 2008) pour dégager des tensions discursives autour des notions de flexibilité et de sécurité dans un corpus de vingt entretiens qualitatifs. L’article permet ainsi de concrétiser l’intérêt et les limites de l’utilisation d’un logiciel d’analyse qualitative dans le cadre d’un travail interdisciplinaire. [less ▲]

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See detailWorking memory deficits in developmental dyscalculia: the importance of serial order.
Attout, Lucie ULg; Majerus, Steve ULg

in Child Neuropsychology : A Journal on Normal & Abnormal Development in Childhood & Adolescence (in press)

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See detailFinancement de la santé et recouvrement des coûts : le lourd fardeau des ménages congolais. Résultats des comptes nationaux de la santé.
Manzambi Kuwekita, Joseph ULg; Eloko Eya Matangelo, Gérard; Bruyère, Olivier ULg et al

in Journal d’Épidémiologie et de Santé Publique (in press)

This study examines the share and allocation of household expenditure in health financing, as presented by the National Health Account figures. These figures are based on a national survey carried out in ... [more ▼]

This study examines the share and allocation of household expenditure in health financing, as presented by the National Health Account figures. These figures are based on a national survey carried out in 2010 among 11,000 households, 2,200 people living with HIV/AIDS, 183 institutions, 42 mutual funds, 18 companies and using the balance sheets of 1,300 companies. Total household health expenditure per capita per year amounted to U.S. $ 4.50. Routine health expenditure is covered by the households (40%) and international cooperation (45%) through direct payment without cost sharing (93.7%). A hospital stay is warranted in case of nutritional deficiencies (34%), malaria (12%) and mental disorders (10%). 82% of outpatient care is related to malaria (71%) and mental disorders (12.5 %). In conclusion, the observation that 71.58% of hospitals expenditure, 96.49% of ambulatory care centres expenditure, 98.48% of medical and diagnosis laboratories expenditure, 72.42% of pharmacies expenditures come from households’ out of pocket expenses calls for the establishment of solidarity mechanisms in the health sector. Outpatient malaria care consumes as much as 71% of household expenditure, and we therefore need to strengthen prevention, treatment and focus on monitoring progress. The fact that nutritional deficiencies are the leading cause of people seeking hospital care suggests that efforts are needed to improve their living conditions of households. Mental disorders are the third leading cause of hospital recourse and this pathology should therefore be included in the minimum and supplementary package of activities. [less ▲]

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See detailCombined use of Ion Mobility and Collision-Induced Dissociation to investigate the opening of disulfide bridges by Electron-Transfer Dissociation in peptides bearing two disulfide bonds
Massonnet, Philippe ULg; Upert, Gregory; Smargiasso, Nicolas ULg et al

in Analytical Chemistry (in press)

Disulfide bonds are post-translational modifications (PTMs) often found in peptides and proteins. They increase their stability towards enzymatic degradations, and provide the structure and (consequently ... [more ▼]

Disulfide bonds are post-translational modifications (PTMs) often found in peptides and proteins. They increase their stability towards enzymatic degradations, and provide the structure and (consequently) the activity of such folded proteins. The characterization of disulfide patterns, i.e the cysteine connectivity, is crucial to achieve a global picture of the active conformation of the protein of interest. Electron Transfer Dissociation (ETD) constitutes a valuable tool to cleave the disulfide bonds in the gas phase, avoiding chemical reduction/alkylation in solution. To characterize the cysteine pairing, the present work proposes (i) to reduce by ETD one of the two disulfide bridges of model peptides , resulting in the opening of the cyclic structures, (ii) to separate the generated species by ion-mobility and, (iii) to characterize the species using CID. Results of this strategy applied to several peptides show different behaviors depending on the connectivity. The loss of SH• radical species, observed for all the peptides, confirms the cleavage of the disulfides during the ETD process. [less ▲]

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See detailGenotype contribution to the chemical composition of banana rachis and implications for thermo/biochemical conversion
Tiappi Deumaga, Mathias Florian; Happi Emaga, Thomas; Tchokouassom, Raphael et al

in Biomass Conversion and Biorefinery (in press)

Chemical composition of banana rachis from three varieties (Grande naine, Pelipita, and CRBP969) was ana- lyzed, and the genotype contribution to composition variabil- ity was investigated. Wet chemistry ... [more ▼]

Chemical composition of banana rachis from three varieties (Grande naine, Pelipita, and CRBP969) was ana- lyzed, and the genotype contribution to composition variabil- ity was investigated. Wet chemistry and instrumental analysis procedures (X-ray diffraction, 31P NMR spectroscopy, and thermogravimetry) were used. Some significant differences were found among the three genotypes: GN-AAA genotype was found to be significantly the highest in ash fraction (30.16 %) and the lowest in acid insoluble lignin (6.58 %) at 95 % confidence level. It showed also the highest content in potassium (43.5 % in ash). Implication of compositional dif- ferences on valorization efficiency by biochemical or thermo- chemical pathways was investigated. For this purpose, corre- lation coefficients between compositional characteristics and yields in volatile compounds from pyrolysis and glucose yields from enzymatic saccharification were analyzed. Ash content was revealed to be the main drawback parameter for volatile yields from pyrolysis (r = −0.93), while for glucose yields during saccharification were limited mainly by the con- tent in guaiacyl units of the lignin fraction (r = −0.98). How- ever, a strong and positive correlation was established be- tween the volatiles yield and the acid insoluble lignin content (r = 0.98) Thus, according to these observations and based on their compositional significant differences, GN-AAA was the better candidate for bioconversion pathway while PPT-ABB and CRBP969-AAAB samples were shown to be better can- didates for thermochemical conversion pathway. This work gives important preliminary information for considering ba- nana rachis as an interesting feedstock candidate for biorefinery. [less ▲]

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See detailDetection of anthropogenic particles in fish stomachs: an isolation method adapted to identification by Raman spectroscopy
Collard, France ULg; Gilbert, Bernard ULg; Eppe, Gauthier ULg et al

in Archives of Environmental Contamination & Toxicology (in press)

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See detailLes tensions entre langue et politique en Belgique: linguistiques ou communautaires?
Dassargues, Alix ULg; Perrez, Julien ULg; Reuchamps, Min ULg

in Revue Internationale de Politique Comparée (in press)

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have ... [more ▼]

Since its creation in 1830, Belgium has experienced tensions between language and politics. The question of the linguistic or community-related nature of these tensions should be raised since they have regularly been referred to as linguistic by some researchers and as community-related by others. But the choice of these adjectives is not unimportant considering they frame the representations of the political issues at hand. The aim of this article is to tackle this question from the combined perspective of linguistics and political science. In the first, the article explores the genealogy of the adjectives ‘linguistic’ and ‘community-related’ as well as the multiplicity of their uses in the scientific literature. In the second part, it focuses on the ways citizens see and talk about Belgian federalism through the respective analyses of their mental representations and their conceptual metaphors. Such interdisciplinary endeavour, bringing together theoretical and empirical insights, seeks to yield a renewed understanding of the political relations in Belgium and to contribute to the debate about plurilingual societies. [less ▲]

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See detailActive Management of Low-Voltage Networks for Mitigating Overvoltages due to Photovoltaic Units
Olivier, Frédéric ULg; Aristidou, Petros ULg; Ernst, Damien ULg et al

in IEEE Transactions on Smart Grid (in press)

In this paper, the overvoltage problems that might arise from the integration of photovoltaic panels into low-voltage distribution networks is addressed. A distributed scheme is proposed that adjusts the ... [more ▼]

In this paper, the overvoltage problems that might arise from the integration of photovoltaic panels into low-voltage distribution networks is addressed. A distributed scheme is proposed that adjusts the reactive and active power output of inverters to prevent or alleviate such problems. The proposed scheme is model-free and makes use of limited communication between the controllers, in the form of a distress signal, only during emergency conditions. It prioritizes the use of reactive power, while active power curtailment is performed only as a last resort. The behavior of the scheme is studied using dynamic simulations on a single low-voltage feeder and on a larger network composed of 14 low-voltage feeders. Its performance is compared to a centralized scheme based on the solution of an Optimal Power Flow problem, whose objective function is to minimize the active power curtailment. The proposed scheme successfully mitigates overvoltage situations due to high photovoltaic penetration and performs almost as well as the Optimal Power Flow based solution with significantly less information and communication requirements. [less ▲]

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See detailCharacterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54, and Their Role in Bacterial Midrib Rot Disease of Lettuce
Huang, CJ; Pauwelyn, E.; Ongena, Marc ULg et al

in Molecular Plant-Microbe Interactions [=MPMI] (in press)

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See detailPhenotypic variability in bioprocessing conditions can be tracked on the basis of on-line flow cytometry and fits to a scaling law
Baert, Jonathan ULg; Kinet, Romain ULg; Brognaux, Alison ULg et al

in Biotechnology Journal (in press)

Noise in gene and protein expression is a major cause for bioprocess deviation. However, this phenomenon has been only scarcely considered in real bioprocessing conditions. In this work, a scaling-law ... [more ▼]

Noise in gene and protein expression is a major cause for bioprocess deviation. However, this phenomenon has been only scarcely considered in real bioprocessing conditions. In this work, a scaling-law derived from a genome-scale studies based on GFP reporter systems has been calibrated to an on-line flow cytometry device, allowing thus to get an insight at the level of promoter activity and associated noise during a whole microbial culture carried out in bioreactor. We show that most of the GFP reporter systems investigated and thus corresponding genes could be included inside the area covered by the scaling-law. The experimental results suggest that this scaling-law could be used to predict the dynamics of promoter activity, as well as the associated noise, in bioprocessing conditions. The knowledge acquired throughout this work could be used for the design of more robust expression systems. [less ▲]

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See detailTien Shan geohazards database: Earthquakes and landslides
Havenith, Hans-Balder ULg; Strom, Alexander; Torgoev, Isakbek et al

in Geomorphology (in press)

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been ... [more ▼]

In this paper we present new and review already existing landslide and earthquake data for a large part of the Tien Shan, Central Asia. For the same area, only partial databases for sub-regions have been presented previously. They were compiled and new data were added to fill the gaps between the databases. Major new inputs are products of the Central Asia Seismic Risk Initiative (CASRI): a tentative digital map of active faults (even with indication of characteristic or possible maximum magnitude) and the earthquake catalogue of Central Asia until 2009 that was now updated with USGS data (to May 2014). The new compiled landslide inventory contains existing records of 1600 previously mapped mass movements and more than 1800 new landslide data. Considering presently available seismo-tectonic and landslide data, a target region of 1200 km (E–W) by 600 km (N–S) was defined for the production of more or less continuous geohazards information. This target region includes the entire Kyrgyz Tien Shan, the South-Western Tien Shan in Tajikistan, the Fergana Basin (Kyrgyzstan, Tajikistan and Uzbekistan) as well as the Western part in Uzbekistan, the North-Easternmost part in Kazakhstan and a small part of the Eastern Chinese Tien Shan (for the zones outside Kyrgyzstan and Tajikistan, only limited information was available and compiled)... [less ▲]

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See detailInhibitory deterioration may contribute to hallucinations in Alzheimer’s disease
El Haj, Mohamad; Laroi, Frank ULg; Gély-Nargeot, Marie-Christine et al

in Cognitive Neuropsychiatry (in press)

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See detailNegentiende-eeuwse anglofilie in Nederland
Steyaert, Kris ULg

in Spiegel der Letteren (in press), 57(3),

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See detailcompte rendu de : James Noel ADAMS, Social Variation and the Latin Language
Rochette, Bruno ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (in press)

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See detailHigh Resolution postontrast time of flight MR angiography of intracranial perforators at 7.0 Tesla
Harteveld, A; de Cocker, L; Dieleman, N et al

in American Journal of Neuroradiology (in press)

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See detailOne injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's knee
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in The Journal of sports medicine and physical fitness (in press)

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]

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See detailOccurrence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary, Argentina, and their mid-distance movements along the Northeast Patagonian coast
Failla, Mauricio; Seijas, Veronica; Vermeulen, Els ULg

in Latin American Journal of Aquatic Mammals (in press)

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data ... [more ▼]

A systematic study on the presence of bottlenose dolphins (Tursiops truncatus) in the Río Negro Estuary (RNE), Patagonia Argentina, was carried out between the months March – July from 2008 to 2011. Data on the dolphin’s activity patterns were gathered via an Ad Libitum focal group sampling mode accompanying dorsal fin images taken for identification and re-identification of individuals. A total effort of 188 h resulted in 58 h of positive observation of 124 dolphin groups (sightings per unit effort (SPUE) = 0.66 groups/h). Data analysis showed two main activity states for the observed groups, travelling (65%) and foraging (26%). The remaining 9% of the groups were involved in other activity states. The photo-identification effort, which started opportunistically in 2006, resulted in a catalogue of 21 individual dolphins, with a total mean re-identification rate of 9 days (max = 24 days). When comparing these pictures to the existing catalogue of Bahía San Antonio (approximately 200 km west from the study area) dorsal fins of 20 individuals could be positively matched and most (n = 17) could be subsequently re-identified in both areas, indicating their long distance movements along the North Patagonian coast during the austral autumn months. This season coincides with the lowest amount of feeding activity observed in Bahía San Antonio. This study suggests that bottlenose dolphins enter RNE, mainly during autumn, to forage. It appears that the search for food resources may be the trigger for their movement patterns along the North Patagonian coast during this season, at least for certain individuals. More research is needed to accurately confirm this hypothesis. [less ▲]

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See detailDrivers of the winter–spring phytoplankton bloom in a pristine NW Mediterranean site, the Bay of Calvi (Corsica): A long-term study (1979–2011)
Goffart, Anne ULg; Hecq, Jean-Henri ULg; Legendre, Louis

in Progress in Oceanography (in press)

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics ... [more ▼]

This work is based on a long time series of data collected in the well-preserved Bay of Calvi (Corsica island, Ligurian Sea, NW Mediterranean) between 1979 and 2011, which include physical characteristics (31 years), chlorophyll a (chl a, 15 years), and inorganic nutrients (13 years). Because samples were collected at relatively high frequencies, which ranged from daily to biweekly during the winter-spring period, it was possible to (1) evidence the key role of two interacting physical variables, i.e. water temperature and wind intensity, on nutrient replenishment and phytoplankton dynamics during the winter-spring period, (2) determine critical values of physical factors that explained interannual variability in the replenishment of surface nutrients and the winter-spring phytoplankton bloom, and (3) identify previously unrecognized characteristics of the planktonic ecosystem. Over the >30 year observation period, the main driver of nutrient replenishment and phytoplankton (chl a) development was the number of wind events (mean daily wind speed >5 m s-1) during the cold-water period (subsurface water ≤13.5°C). According to winter intensity, there were strong differences in both the duration and intensity of nutrient fertilization and phytoplankton blooms (chl a). The trophic character of the Bay of Calvi changed according to years, and ranged from very oligotrophic (i.e. subtropical regime, characterized by low seasonal variability) to mesotrophic (i.e. temperate regime, with a well-marked increase in nutrient concentrations and chl a during the winter-spring period) during mild and moderate winters, respectively. A third regime occurred during severe winters characterized by specific wind conditions (i.e. high frequency of northeasterly winds), when Mediterranean “high nutrient - low chlorophyll” conditions occurred as a result of enhanced cross-shore exchanges and associated offshore export of the nutrient-rich water. There was no long-term trend (e.g. climatic) in either nutrient replenishment or the winter-spring phytoplankton bloom between 1979 and 2011, but both nutrients and chl a reflected interannual and decadal changes in winter intensity. [less ▲]

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See detailUsing platelet-rich plasma to treat jumper's knees: Exploring the effect of a second closely-timed infiltration
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Journal of Science and Medicine in Sport (in press)

Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove ... [more ▼]

Some clinical series have evaluated the effect of platelet-rich plasma (PRP) in the treatment of proximal patellar tendinopathy. Although it is possible that a single infiltrative administration may prove to be an effective treatment for this indication, most of the existing studies evaluated the effects of two or three successive infiltrations. The aim of this study was to evaluate whether two infiltrations of PRP proves more effective than a single treatment. DESIGN: Prospective, randomized and comparative study of level 2. METHODS: Twenty patients suffering from chronic proximal patellar tendinopathy were enrolled into the study and split into two randomized groups (one or two infiltrations of PRP, respectively). The 3-month follow-up evaluation consisted of VAS, IKDC and VISA-P scores, along with algometer, isokinetic and ultrasounds evaluations. After 1 year, subjects were contacted to define their functional evolution. RESULTS: The concentration of the PRP used for each infiltration was similar in both groups, and contained no red or white cells. Results revealed no difference in treatment efficacy between the groups. CONCLUSIONS: The comparison between one or two infiltrations of PRP did not reveal any difference between the two groups at short to mid term. A second closely-timed infiltration of PRP to treat proximal patellar tendinopathies is not necessary to improve the efficacy of this treatment in the short term. [less ▲]

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See detailState Created Barriers to Exit - The Example of the Acquisition of Alstom by General Electric
Petit, Nicolas ULg

in Competition Policy International (in press)

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailLa pollution lumineuse, entre écologie et santé
JEDIDI, Haroun ULg; DEPIERREUX, Frédérique ULg; JEDIDI, Zayd ULg et al

in Revue Médicale de Liège (in press)

Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution ... [more ▼]

Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution is a quite recent and increasing phenomenon within our society and it leads to a major environmental damage, obviously near wildlife, but also on human health (cancers, obesity, fatigue, depression...). The solutions to this problem are however simple, efficient and de facto inexpensive and involving a substantial energy saving. [less ▲]

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See detailNewt life after fish introduction: extirpation of paedomorphosis in a mountain fish lake and newt use of satellite pools
Denoël, Mathieu ULg; Scime, Patrick; Zambelli, Nicola

in Current Zoology (in press), 62

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context ... [more ▼]

Fish introduction is one of the main causes of amphibian decline worldwide. It affects particularly rare aquatic phenotypes such as paedomorphs, which retain gills during the adult stage. In this context, we determined whether small wetlands, such as pools surrounding fished and fishless lakes, could sustain paedomorphic and metamorphic newts. To this end, we surveyed lakes known historically to sustain Alpine newts (Ichthyosaura alpestris) as well as 35 nearby pools. On the basis of the published records, the only known population exhibiting paedomorphosis in the Swiss Alps was found to be extirpated by salmonid introductions. However, the metamorphs persisted in peripheral pools, paedomorphosis was discovered at a new locality, and overwintering larvae were still present in one of the lakes. These results show the importance of conserving varied aquatic habitats such as pools in mountainous environments where the main resources can become unsuitable for amphibians because of fish introductions. Pools may also function as reservoirs in maintaining newt populations until programs to remove fish from lakes can be carried out. It is not known if paedomorphs could reappear after fish removal. However, the combined resilience of amphibians after fish removal and the genetic basis for paedomorphosis highlighted in other taxa by previous studies suggest that there is the potential to maintain this intraspecific case of diversity even after its disappearance. [less ▲]

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See detailThe aggressive personality of an introduced fish affects foraging behavior in a polymorphic newt
Winandy, Laurane ULg; Denoël, Mathieu ULg

in Behavioral Ecology (in press)

The study of personality has aroused much interest and has provided insight into the understanding of animal behavior. Nevertheless, the study of the ecological consequences of personality is a newer ... [more ▼]

The study of personality has aroused much interest and has provided insight into the understanding of animal behavior. Nevertheless, the study of the ecological consequences of personality is a newer field that could shed light on cases of alien species introductions. The goldfish (Carassius auratus) is frequently introduced worldwide and affects the abundance of newts, having an especially negative impact on an alternative phenotype, the paedomorph, which maintains larval traits at the adult stage, unlike the other phenotype, the metamorph, which has undergone metamorphosis. We experimentally assessed the impact of goldfish on the foraging behavior of both phenotypes of palmate newts (Lissotriton helveticus). More particularly, we assessed fish personality by analyzing the foraging activity and the aggressiveness toward newts, and newt personality by analyzing individual difference in boldness. In the presence of fish, fewer newts foraged than in their absence, and paedomorphs were more affected than metamorphs. We found strong personality differences in fish and fewer newts foraged in the presence of a more aggressive fish. Newts differed in boldness, but fish aggressiveness remains a key factor to explain newt behavior. Studying behavioral interactions between native and alien species helps to understand the mechanisms of coexistence and exclusion and why different phenotypes might be affected differently by the same threat. To a great extent, not only the presence of fish alters the foraging opportunities of newts but also the personality of the invader; integrating personality patterns of invaders is therefore a key to understanding the ecological consequences of alien species introduction. [less ▲]

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See detailDiversity of germination strategies and dormancy of graminoid and forb species of campo rupestre grasslands
Le Stradic, Soizig ULg; Silveira, Fernando A. O.; Buisson, Elise et al

in Austral Ecology (in press)

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See detailLaser cladding as repair technology for Ti6Al4V alloy: Influence of building strategy on microstructure and hardness
Paydas, Hakan ULg; Mertens, Anne ULg; Carrus, Raoul et al

in Materials & Design (in press)

Laser cladding is a metal deposition technique used to fabricate or repair components made from high value metallic alloys. In the present work Ti-6Al-4V deposits with variable thickness are made to ... [more ▼]

Laser cladding is a metal deposition technique used to fabricate or repair components made from high value metallic alloys. In the present work Ti-6Al-4V deposits with variable thickness are made to assess the use of laser cladding as a repair technology. Both the effect of the building strategy (BS) and the incident energy (IE) on the metallurgical characteristics of the deposits in relation to their complex thermal history have been studying. It is shown that for the configuration consisting in a decreasing track length (DTL) under high IE, a gradient of cooling rate exists that leads to the presence of different phases within the microstructure. Conversely homogeneous microstructures are present either for the configuration with a constant track length (CTL) under high IE, and for the strategy obtained from a DTL under low IE. Depending on the possible heat accumulation the nature of the phases are determined together with hardness maps within the deposits. Some qualification criteria are set prior to tensile tests to selected the adequate candidate-deposit that does not weaken the cladded material when it is stressed. A thermo-metallurgical scheme is proposed that helps understanding the effect of both the BS and the IE on the microstructure. [less ▲]

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See detailDefining multiplication in some additive expansions of polynomial rings
Point, Françoise; Rigo, Michel ULg; Waxweiler, Laurent

in Communications in Algebra (in press)

Adapting a result of R. Villemaire on expansions of Presburger arithmetic, we show how to define multiplication in some expansions of the additive reduct of certain Euclidean rings. In particular, this ... [more ▼]

Adapting a result of R. Villemaire on expansions of Presburger arithmetic, we show how to define multiplication in some expansions of the additive reduct of certain Euclidean rings. In particular, this applies to polynomial rings over a finite field. [less ▲]

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See detailLa manie et la mélancolie comme crises de l’identité narrative et de l’intentionnalité
Englebert, Jérôme ULg; Stanghellini, Giovanni

in Evolution Psychiatrique (in press)

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the ... [more ▼]

Objectives: Our objective is to achieve a phenomenological cross-study of melancholic and manic crises. To do this, we analyze the relationship between these two psychopathological states by means of the concepts of "narrative identity" and "intentionality". Method: From clinical cases and with reference to various theoretical models derived from phenomenological psychopathology, we discuss similarities and differences between mania and melancholia. Results: Narrative identity is based on a double movement: that of the enunciation of a speech focused on his history and that of an act of creation. From different clinical situations, we find that: (1) the melancholic retains the ability to elaborate a narrative about his history but the creative dimension of this narrative is absent, and (2) conversely, the manic experiences only the creative dimension. Discussion: Intentionality, as the tendency of consciousness to move toward something beyond itself, proves to be the center of the manic existence without being able to set itself within the boundaries of factual constraints. The melancholic, conversely, experiences an existence in which consciousness has lost its capacity to aim beyond itself. Conclusions: Melancholia and mania are quite specific forms of being-in-world with particular identity and temporal experiences. These two states share a fundamental psychopathological feature, that we named here “manque chiasmatique”: they are disorders of the intentional movement that constitutes narrative identity, that is, of the dialectics between the rootedness (“enracinenment”) of self in its past and the possibility of creation of a new identity. [less ▲]

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailGlioblastoma-derived extracellular vesicles induce tumor-supportive phenotypes in monocytic cells
de Vrij, Jeroen; Maas, Sybren; Kwappenberg, Kitty et al

in International Journal of Cancer = Journal International du Cancer (in press)

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See detailComique et didactique : le rire en classe de langue ?
Defays, Jean-Marc ULg

in Vivre le Français : Revue de l'Association Belge des Professeurs de Français (in press), 245

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See detailRecurrent pulsations in Saturn’s high latitude magnetosphere
Mitchell, D.G.; Carbary, J.F.; Bunce, E.J. et al

in Icarus (in press)

Detailed reference viewed: 12 (3 ULg)