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See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

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See detailNew insight on Carboniferous (Viséan) brachiopods from eastern Tafilalt (Morocco)
Mottequin, Bernard; Denayer, Julien ULg; Herbig, Hans-Georg et al

in Geological Journal (in press)

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See detailPower System Dynamic Simulations using a Parallel Two-level Schur-complement Decomposition
Aristidou, Petros; Lebeau, Simon; Van Cutsem, Thierry ULg

in IEEE Transactions on Power Systems (in press)

As the need for faster power system dynamic simulations increases, it is essential to develop new algorithms that exploit parallel computing to accelerate those simulations. This paper proposes a parallel ... [more ▼]

As the need for faster power system dynamic simulations increases, it is essential to develop new algorithms that exploit parallel computing to accelerate those simulations. This paper proposes a parallel algorithm based on a two-level, Schur complement-based, domain decomposition method. The two-level partitioning provides high parallelization potential (coarse and fine-grained). In addition, due to the Schur-complement approach used to update the sub-domain interface variables, the algorithm exhibits high global convergence rate. Finally, it provides significant numerical and computational acceleration. The algorithm is implemented using the shared-memory parallel programming model, targeting inexpensive multi-core machines. Its performance is reported on a real system as well as on a large test system combining transmission and distribution networks. [less ▲]

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See detailImaginer-lire le Capital
Pieron, Julien ULg

in Cahiers d'Etudes Germaniques (in press)

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See detailULTRASONOGRAPHIC FINDINGS IN 13 HORSES WITH LYMPHOMA
Janvier, Valentin; Evrard, Laurence ULg; Cerri, Simona ULg et al

in Veterinary Radiology & Ultrasound (in press)

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See detailÂgisme et surestimation des difficultés cognitives des personnes âgées: une revue de la question
Marquet, Manon ULg; Missotten, Pierre ULg; Adam, Stéphane ULg

in Gériatrie et Psychologie Neuropsychiatrie du Vieillissement (in press)

Stigmatization related to age (i.e., ageism) is a widespread phenomenon in the modern industrial societies where older people are perceived as cognitively incompetent. Therefore negative stereotypes about ... [more ▼]

Stigmatization related to age (i.e., ageism) is a widespread phenomenon in the modern industrial societies where older people are perceived as cognitively incompetent. Therefore negative stereotypes about age-related cognitive decline may have a detrimental influence on older adults on their cognitive performance. The aim of the present review is to understand how stereotypes can influence the performance of the elderly on cognitive tests.We first describe the stereotype threat phenomenon by providing an overview of situations likely to produce stereotype threat, aswell as contextual and personal characteristics that moderate its effects. Possible mechanisms underlying these influences on cognitive performance are also presented. Secondly, we address self-stereotyping, which explains long-term negative effects of stereotypes and their unconscious influence on older adults’ cognitive performance. However, some age stereotypes are also have positive effects on aged people, as shown by some studies describing such benefic effects of positive stereotypes on cognitive performance. Finallywe try to understand why negative age stereotyping has a much stronger influence on important behavioral outcomes among older adults than does positive age stereotyping. Given all these results, we examine how negative age stereotypes may impact older adults’ cognitive performance in real-world settings such as during a cognitive assessment. [less ▲]

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See detailUn type picard par-delà les frontières : le <nom jeté>
Baiwir, Esther ULg

in Dialectes de Wallonie (in press), 36

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See detailLate Pleistocene molecular dating of past population fragmentation and demographic changes in African rain forest tree species supports the forest refuge hypothesis
Duminil, Jérôme; Mona, Stefano; Mardulyn, Patrick et al

in Journal of Biogeography (in press)

Aim : Phylogeographical signatures of past population fragmentation and demographic change have been reported in several African rain forest trees. These signatures have usually been interpreted in the ... [more ▼]

Aim : Phylogeographical signatures of past population fragmentation and demographic change have been reported in several African rain forest trees. These signatures have usually been interpreted in the light of the Pleistocene forest refuge hypothesis, although dating these events has remained impracticable because of inadequate genetic markers. We assess the timing of interspecific and intraspecific genetic differentiation and demographic changes within two rain forest Erythrophleum tree species (Fabaceae: Caesalpinioideae). Location : Tropical forests of Upper Guinea (West Africa) and Lower Guinea (Atlantic Central Africa). Methods : Six single-copy nuclear genes were used to characterize the phylogeographical patterns of the parapatric sister species Erythrophleum suaveolens (characteristic of semi-deciduous or gallery forests) and Erythrophleum ivorense (characteristic of evergreen forests). The number of gene pools within each species was determined and the timings of their divergence and past demographic changes were estimated using Bayesian-based coalescent approaches. Results : Three geographically separated gene pools were identified within E. suaveolens, and a single gene pool was inferred in E. ivorense. All gene pools show signatures of demographic bottlenecks concomitant with the last glacial period (c. 120–12 ka). Species-tree inferences show that the two species diverged c. 600 ka, whereas the divergence between E. suaveolens gene pools was dated to the late Pleistocene (first divergence c. 120 ka, second c. 60 ka). Main conclusions : (1) Molecular dating of demographic changes of two African tropical forest tree species is consistent with the Pleistocene forest refuge hypothesis. (2) Tree species from Guinean evergreen tropical forests might have been less affected by past climate change than semi-deciduous species. (3) Our phylogeographical data support a recent date (Holocene) of the last opening of the Dahomey Gap. [less ▲]

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See detailA Theory of Soft Capture
Agrell, Per; Gautier, Axel ULg

in Scandinavian Journal of Economics (in press)

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to ... [more ▼]

n this paper, wee propose a model for regulatory capture that is based on information transmission and asymmetric information. In a three-tier model, a regulator is charged by a political principal to provide a signal for the type of a regulated firm. Only the firm can observe his type and the production of a correlated signal with a given accuracy is costly for the regulator. The firm can costlessly provide an alternative signal of lower accuracy that is presented to the regulator. In a self-enforcing equilibrium, the regulator transmits the firm-produced signal, internalizes its own savings in information cost and the firm enjoys higher information rents. The main feature of soft capture is that it is not based on a reciprocity of favors but on a congruence of interests between the firm and the regulator. [less ▲]

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See detailLe Mur et le masque. À propos de Banksy.
Saint-Amand, Denis ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailIs the sword moss (Bryoxiphium) a preglacial Tertiary relict?
Patino, J.; Goffinet, B.; Sim-Sim, M.A. et al

in Molecular Phylogenetics & Evolution (in press)

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See detailTeletê peut-elle être déesse ? Note épigraphique (SEG 50, 168)
Pirenne-Delforge, Vinciane ULg

in Mètis : Revue d'Anthropologie du Monde Grec Ancien : Philologie, Histoire, Archéologie (in press)

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See detailExperimental Tests and Numerical Modelling on Slender Steel Columns at High Temperatures
Franssen, Jean-Marc ULg; Zhao, Bin; Gernay, Thomas ULg

in Journal of Structural Fire Engineering (in press)

This paper is about a series of experimental fire tests on eight full scale steel columns made of slender I shaped class 4 sections. Six columns were made of welded sections (some prismatic and some ... [more ▼]

This paper is about a series of experimental fire tests on eight full scale steel columns made of slender I shaped class 4 sections. Six columns were made of welded sections (some prismatic and some tapered members) and two columns were made of hot rolled sections. The nominal length of the columns was 2.7 meters with the whole length being heated. The load was applied at ambient temperature after which the temperature was increased under constant load. The load was applied concentrically on some tests and with an eccentricity in other tests. Heating was applied by electrical resistances enclosed in ceramic pads. Numerical simulations were performed with the software SAFIR® using shell elements. The paper presents the results obtained in terms of failure mode and ultimate temperature, in the experimental tests and in the numerical simulations. [less ▲]

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See detailContribution of distribution network control to voltage stability: A case study
Aristidou, Petros ULg; Valverde, Gustavo; Van Cutsem, Thierry ULg

in IEEE Transactions on Smart Grid (in press)

A case study dealing with long-term voltage instability in systems hosting active distribution networks is reported in this paper. It anticipates future situations with high penetration of dispersed ... [more ▼]

A case study dealing with long-term voltage instability in systems hosting active distribution networks is reported in this paper. It anticipates future situations with high penetration of dispersed generation, where the latter are used to keep distribution voltages within desired limits, in complement to load tap changers. The interactions between transmission and active distribution networks are investigated on a 3108-bus test system. It involves transmission grid, large generators, and forty distribution networks, each with dispersed generation steered by a controller inspired of model predictive control. The reported simulations show the impact of distribution network voltage restoration as well as the benefit of load voltage reduction actuated by the dispersed generators. [less ▲]

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See detailLarge-Eddy Simulations of microcarrier exposure to potentially damaging eddies inside mini-bioreactors
Collignon, Marie-Laure ULg; Delafosse, Angélique; Calvo, Sébastien ULg et al

in Biochemical Engineering Journal (in press)

Mechanically stirred vessels equipped with rotating impellers generate heterogeneous transitional or turbulent flows. However, some cells as animal or human mesenchymal stem cells (hMSC) adhered on ... [more ▼]

Mechanically stirred vessels equipped with rotating impellers generate heterogeneous transitional or turbulent flows. However, some cells as animal or human mesenchymal stem cells (hMSC) adhered on microcarriers, are reputed sensitive to hydromechanical stresses arising from stirring. Many publications, especially using Computational Fluid Dynamics, characterize spatial fields of velocity and turbulence inside bioreactors but the exposure frequency to these stresses is never taken into account in the case of animal cell culture bioreactor description. To fill this gap, this study used both CFD Reynolds-Averaged and Large-Eddy Simulations to characterize the hydrodynamics inside 250 mL mini-bioreactors, which is a relevant volume for hMSC cultures. Five impeller geometries were studied. From the velocity and turbulence fields calculated, an energy dissipation/circulation function, related to both frequency and intensity of potentially damaging hydrodynamic events for the cells, was determined for various operating conditions. Based on the simulation results, the marine propeller operating in up-pumping mode seems to be the most adapted condition, since it exhibits a low frequency of exposure to an acceptable intensity of the turbulent dissipation rate. From a general point of view, the new methodology proposed should be used in the future to screen the most adapted bioreactor geometry to biological constraints. [less ▲]

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See detailHigh Resolution postontrast time of flight MR angiography of intracranial perforators at 7.0 Tesla
Harteveld, A; de Cocker, L; Dieleman, N et al

in American Journal of Neuroradiology (in press)

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See detailThe Sceptical President: Václav Klaus' Influence on Czech Public Opinion on Climate Change
De Pryck, Kari; Gemenne, François ULg

in Climatic Change (in press)

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See detailCo-simulation of Electromagnetic Transients and Phasor Models: a Relaxation Approach
Plumier, Frédéric ULg; Aristidou, Petros; Geuzaine, Christophe ULg et al

in IEEE Transactions on Power Delivery (in press)

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this ... [more ▼]

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this paper, a relaxation approach is presented, iterating between an EMT and a PM solver. This entails interpolating over time the phasors of the PM simulation, extracting phasors from the time evolutions of the EMT simulation, and representing each sub-system by a proper multiport equivalent when simulating the other sub-system. Various equivalents are reviewed and compared in terms of convergence of the PM-EMT iterations. The paper also considers the update with frequency of the Thévenin impedances involved in the EMT simulation, the possibility to compute the EMT solution only once per time step, and the acceleration of convergence through a prediction over time of the boundary variables. Results are presented on a 74-bus, 23-machine test system, split into one EMT and one PM sub-system with several interface buses. [less ▲]

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailProjecting the self into the future in individuals with schizophrenia: a preliminary cross-sectional study.
Raffard, Stephane; Bortolon, Catherine; D'Argembeau, Arnaud ULg et al

in Memory (in press)

The ability to project oneself into the future contributes to development and maintenance of a coherent sense of identity. If recent research has revealed that schizophrenia is associated with ... [more ▼]

The ability to project oneself into the future contributes to development and maintenance of a coherent sense of identity. If recent research has revealed that schizophrenia is associated with difficulties envisioning the future, little is known about patients' future self-representations. In this study, 27 participants with schizophrenia and 26 healthy controls were asked to simulate mental representations of plausible and highly significant future events (self-defining future projections, SDFPs) that they anticipate to happen in their personal future. Main results showed that schizophrenia patients had difficulties in reflecting on the broader meaning and implications of imagined future events. In addition, and contrary to our hypothesis, a large majority of SDFPs in schizophrenia patients were positive events, including achievements, relationship, and leisure contents. Interestingly, patients and controls did not differ on the perceived probability that these events will occur in the future. Our results suggest that schizophrenia patients have an exaggerated positive perception of their future selves. Together, these findings lend support to the idea that past and future self-defining representations have both similar and distinct characteristics in schizophrenia. [less ▲]

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See detailIncreased diversification rates correlate with bisexuality in liverworts
Laenen, B.; Machac, A.; Gradstein, S.R. et al

in New Phytologist (in press)

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See detailA cross-sectional analysis of developmental trajectories of vocabulary comprehension among children and adolescents with Down syndrome or intellectual disability of undifferentiated aetiology
Facon, Bruno; Courbois, Yannick; Magis, David ULg

in Journal of Intellectual & Developmental Disability (in press)

Background: This work seeks to expand our knowledge of developmental trajectories of subcomponents of the language systems of individuals with intellectual disability (ID). It aims to explore how general ... [more ▼]

Background: This work seeks to expand our knowledge of developmental trajectories of subcomponents of the language systems of individuals with intellectual disability (ID). It aims to explore how general and relational vocabularies evolve as a function of cognitive level. Method: Developmental trajectories of general and relational vocabulary comprehension were compared among typically developing children (TYP) and children and adolescents with ID of undifferentiated aetiology (UND) or Down syndrome (DS). Results: Comparisons between TYP and UND participants showed no interaction between cognitive level and diagnostic status for general vocabulary, and only a very weak interaction for relational vocabulary. Comparisons between TYP and DS participants failed to reveal groupspecific trajectories. Performance in general vocabulary was higher than in relational vocabulary for both UND and DS participants. Conclusion: The developmental trajectories of vocabulary appear to be globally comparable for participants with or without ID. [less ▲]

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See detailDPSC colonization of functionalized 3D textiles
Ortiz, Marine; Rosales-Ibáñez, R; Pozos-Guillén, A. et al

in Journal of Biomedical Materials Research, Part B : Applied Biomaterials (in press)

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See detailLoop
Levaux, Christophe ULg

in Rock Music Studies (in press)

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See detailEnergy conservation properties of Ritter solution for idealized dam break flow
Dewals, Benjamin ULg; Bruwier, Martin ULg; Erpicum, Sébastien ULg et al

in Journal of Hydraulic Research (in press)

We examine different aspects of energy conservation in the case of the analytical solution of Ritter for idealized dam break flow in a horizontal frictionless and dry channel. We detail the application of ... [more ▼]

We examine different aspects of energy conservation in the case of the analytical solution of Ritter for idealized dam break flow in a horizontal frictionless and dry channel. We detail the application of the unsteady Bernoulli equation in this case and highlight that the inertial effects cancel out when averaged over the whole flow region. We also show that the potential and kinetic contributions to the total mechanical energy in the flow region have a distinct and constant relative importance: potential energy accounts for 60 %, and kinetic energy for 40 % of the total mechanical energy. These properties of Ritter solution are rarely emphasized while they may be of practical relevance, particularly for the verification of numerical schemes with respect to their ability to ensure energy conservation. [less ▲]

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See detailCompte rendu du Nouveau Répertoire de mises en prose (XIVe–XVIe siècle)
Lambert, Adelaïde ULg

in Moyen Age (Le) (in press)

Compte rendu du Nouveau Répertoire issu du projet international « Refaire Doutrepont » (Progetto PRIN 2009 EAF4CL). Le volume comprend 78 notices de mises en prose : Alexandre le Grand de Jean Wauquelin ... [more ▼]

Compte rendu du Nouveau Répertoire issu du projet international « Refaire Doutrepont » (Progetto PRIN 2009 EAF4CL). Le volume comprend 78 notices de mises en prose : Alexandre le Grand de Jean Wauquelin (S. Hériché-Pradeau), Anséïs de Carthage (Fr. Suard), Baudouin de Flandres (M. Colombo Timelli), Belle Hélène de Constantinople de Jean Wauquelin (M.-Cl. de Crécy), Belle Hélène de Constantinople anonyme (B. Ferrari), Bérinus (Chr. Ferlampin-Acher), Bertrand du Guesclin, v. A et AC (Y. Vermijn), Bertrand du Guesclin, v. B et BC (Y. Vermijn), Beuve de Hantone (J.-P. Martin), Blancandin (R. A. Greco), Cardenois (Cl. Lagomarsini), Châtelain de Coucy (Fr. Suard), Chronique de France jusque 1380 (F. Suard), Chroniques et conquêtes de Charlemagne (B. Guidot), Ciperis de Vignevaux (Cl. Roussel et L. Ramello), Cleomadés (F. Maillet), Clamadés (F. Maillet), Cligés (M. Colombo Timelli), Conquête de Trébisonde (S. Baudelle-Michels), Conte de la charrette (A. Combes), Doolin de Maience (M. Colombo Timelli), Erec (M. Colombo Timelli), Fierabras anonyme (Fr. Suard), Fierabras de Jean Bagnyon (Fr. Suard), Florent et Lyon (P. Di Luca), Florent et Octavien (P. Di Luca), Floriant et Florete (R. Trachsler), Florimont, ms. fr. 12566 (M.-M. Castellani), Florimont, mss. fr. 1490 et Ars. 3476 (Ch. Concina), Florimont, imprimé (Ch. Concina), Galien le Restoré (B. Guidot), Garin de Monglane (H. Gallé), Généalogie de Godefroi de Bouillon de Pierre Desray (I. Weill et Fr. Suard), Gérard de Nevers (M. Marchal), Gérart de Roussillon de Jean Wauquelin (M.-Cl. de Crécy), Abrégé du Gérart de Roussillon (M.-Cl. de Crécy et A. Schoysman), Gérard du Frattre de Jacques Le Gros (Fr. Suard), Gérard d’Euphrate de Jean Maugin (Fr. Suard), Geste du Chevalier au cygne de Berthault de Villebresme (I. Weill et Fr. Suard), Giglan de Claude Platin (S. Lefèvre), Gilles de Chin (A. Petit et A. Schoysman), Godefroi de Bouillon (I. Weill et Fr. Suard), Guérin de Montglave (Fr. Suard), Gui de Warwick et herolt d’Ardenne (O. Merisaldo), Guillaume de Palerne de Pierre Durand (M. Colombo Timelli), Guillaume d’Orange (N. Henrard), Histoire de Charles Martel (A. Schoysman et J.-Ch. Herbin), Huon de Bordeaux (C. Cazanave), Jean d’Avennes (A. M. Finoli et M. Colombo Timelli), Jourdain de Blaves, pr. I (O. Delsaux), Jourdain de Blaves, pr. II (O. Delsaux), Livre de Regnart (E. Suomela-Härmä), Lorrains, Arsenal (J.-Ch. Herbin), Lorrains de Philippe de Vigneulles (J.-Ch. Herbin), Manequine de Jean Wauquelin (M. Colombo Timelli), Meurvin (Cl. Roussel), Milles et Amys (A. Velissariou), Mort d'Aude (G. Palumbo), Myreur des Histors de Jean d’Outremeuse (G. Palumbo), Neuf Preux de Sébastien Mamerot (M. Milani), Ogier le Danois (M. Ott), Pèlerinage de Vie Humaine (Fr. Bourgeois), Pèlerinage de l'âme de Jean Galopes (Fr. Duval), Perceval le Gallois (M. Colombo Timelli), Reine Berthe (A. Schoysman), Renaut de Montauban ou Les quatre fils Aymon, prose vulgate (S. Baudelle-Michels), Renaut de Montauban, prose bourguignonne (S. Baudelle-Michels, D. Quéruel et S. Hériché-Pradeau), Richard sans Peur de Gilles Corrozet (É. Gaucher), Robert le Diable (M. Ricci), Roman de la Rose moralisé de Jean Molinet (J. Devaux), Roman de Troie, pr. 1, 2, 3, 4 et 5 (L. Barbieri), Théséus de Cologne (M. Bacquin), Valentin et Orson (Sh. Schwam-Baird), Vengeance de Notre Seigneur ou Destruction de Jérusalem (B. Ferrari). [less ▲]

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See detailThe network model of depression as a basis for new therapeutic strategies for treating major depressive disorder in Parkinson’s disease
D'Ostilio, Kevin ULg; Garraux, Gaëtan ULg

in Frontiers in Human Neuroscience (in press)

The high prevalence of major depressive disorder in people with Parkinson's disease, its negative impact on health-related quality of life and the low response rate to conventional pharmacological ... [more ▼]

The high prevalence of major depressive disorder in people with Parkinson's disease, its negative impact on health-related quality of life and the low response rate to conventional pharmacological therapies call to seek innovative treatments. Here, we review the new approaches for treating major depressive disorder in patients with Parkinson's disease within the framework of the network model of depression. According to this model, major depressive disorder reflects maladaptive neuronal plasticity. Non-invasive brain stimulation using high frequency repetitive transcranial magnetic stimulation over the prefrontal cortex has been proposed as a feasible and effective strategy with minimal risk. The neurobiological basis of its therapeutic effect may involve neuroplastic modifications in limbic and cognitive networks. However, the way this networks reorganize might be strongly influenced by the environment. To address this issue, we propose a combined strategy that includes non-invasive brain stimulation together with cognitive and behavioral interventions. [less ▲]

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See detailA qPCR aptasensor for sensitive detection of aflatoxin M1
Guo, Xiaodong; Wen, Fang; Zheng, Nan et al

in Analytical and Bioanalytical Chemistry (in press)

Aflatoxin M1 (AFM1), one of the most toxic mycotoxins, imposes serious health hazards. AFM1 had previously been classified as a group 2B carcinogen1 and has been classified as a group 1 carcinogen by the ... [more ▼]

Aflatoxin M1 (AFM1), one of the most toxic mycotoxins, imposes serious health hazards. AFM1 had previously been classified as a group 2B carcinogen1 and has been classified as a group 1 carcinogen by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO).2 Determination of AFM1 thus plays an important role for quality control of food safety. In this work, a sensitive and reliable aptasensor was developed for the detection of AFM1. The immobilization of aptamer through a strong interaction with biotin–streptavidin was used as a molecular recognition element, and its complementary ssDNA was employed as the template for a real-time quantitative polymerase chain reaction (RT-qPCR) amplification. Under optimized assay conditions, a linear relationship (ranging from 1.0×10-4 to 1.0 µg L-1) was achieved with a limit of detection (LOD) down to 0.03 ng L-1. In addition, the aptasensor developed here exhibits high selectivity for AFM1 over other mycotoxins and small effects from cross-reaction with structural analogs. The method proposed here has been successfully applied to quantitative determination of AFM1 in infant rice cereal and infant milk powder samples. Results demonstrated that the current approach is potentially useful for food safety analysis, and it could be extended to a large number of targets. [less ▲]

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See detailParametric Stein operators and variance bounds
Swan, Yvik ULg; Ley, Christophe

in Brazilian Journal of Probability and Statistics (in press)

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See detailTreatment of Multiple Myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group
Sonneveld, Pieter; Avet-Loiseau, Hervé; Lonial, Sagar et al

in Blood (in press)

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See detailLes associations des enfants et jeunes travailleurs du Burkina Faso comme espace d’expression de la capacité d’action des enfants ?
Wouango, Joséphine ULg

in Enfances Familles Générations (in press)

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années ... [more ▼]

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années 1980. Le mouvement est fondé sur deux grands principes : les douze droits prioritaires des enfants et jeunes travailleurs et le principe du « protagonisme » (l’enfant travailleur comme acteur capable) . Ce chapitre présente et analyse le fonctionnement de ce mouvement au Burkina Faso, les changements qu’il a contribué à apporter à la question sociale du travail des enfants et les résultats de la mise en application des principes annoncés. S’appuyant sur une enquête ethnographique menée en son sein, le texte offre des données inédites sur les réalités d’un acteur collectif qui, en utilisant à son avantage la rhétorique de la « participation » des enfants (art.12, Convention des droits de l’enfant), a réussi à s’insérer dans l’arène nationale de la protection de l’enfance. Toutefois, la question de la place et du rôle des enfants ainsi que celle du “vieillissement” des membres sont quelques-uns des défis auxquels la section burkinabè du mouvement doit faire face. [less ▲]

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See detailLevallois et Gravettien
Otte, Marcel ULg; Noiret, Pierre ULg

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]

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See detailInsecticidal activity of Lavandula angustifolia Mill. against Acyrtosiphum pisum
Attia, Sabrine; Lognay, Georges ULg; Heuskin, Stéphanie ULg et al

in journal of entomology and zoology studies (in press)

The essential oil of Lavandula angustifolia was investigated for its biocide activity against Acyrtosiphum pisum by fumigation. The oil was characterised by GC-MS revealing that linalool was the most ... [more ▼]

The essential oil of Lavandula angustifolia was investigated for its biocide activity against Acyrtosiphum pisum by fumigation. The oil was characterised by GC-MS revealing that linalool was the most abundant component (38.57%), followed by linalyl acetate (29.95%), 1,8-cineole (13,66%), camphor (13,13%), -pinene (3,14%) and terpinene-4-ol (1,54%). The Mortality was measured upon treatment with oil concentrations ranging from 5 to 25 µl.l-1 of air. The mortality of aphids increased with oil concentration and LC50 values were determined to be 11.2 µl.l-1 of air. The full mixture was also prepared and toxicity was compared with individual constituents. The results showed that the presence of all constituents were necessary to equal the toxicity of the natural oils L. angustifolia oil can provide valuable pesticide activity with significantly lower LC50 values [less ▲]

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See detailAqueous sol-gel synthesis and film deposition methods for the large-scale manufacture of coated steel with self-cleaning properties
Mahy, Julien ULg; Léonard, Géraldine ULg; Pirard, Sophie ULg et al

in Journal of Sol-Gel Science and Technology (in press)

A process has been developed to enable the large scale production of pure TiO2 films deposited on 316L stainless steel in order to get an easy-to-clean surface. This large scale process requires an easy ... [more ▼]

A process has been developed to enable the large scale production of pure TiO2 films deposited on 316L stainless steel in order to get an easy-to-clean surface. This large scale process requires an easy aqueous sol-gel procedure for the synthesis of the TiO2 sol. This synthesis has been simplified to facilitate the extrapolation towards an industrial scale. Results of TEM, photocatalytic properties, film hydrophilicity, and texture obtained with the simplified aqueous sol-gel synthesis (IsoP-TiO2 synthesis) show similar properties to those obtained with the standard aqueous sol-gel synthesis of TiO2 (HAc-TiO2 synthesis) developed previously. Only X-Ray Diffraction patterns showed differences, with the presence of anatase-brookite phases in IsoP-TiO2 synthesis while anatase phase only was observed in HAc-TiO2 synthesis. Both the aqueous sol-gel synthesis of pure TiO2 and the film deposition on steel by roll-coating have been successfully extrapolated to a larger scale. The photocatalytic activity and the hydrophilicity of the film were found to be unchanged when compared to films produced at a laboratory scale, thus validating the production of an efficient easy-to-clean material. Although some problems are still to be solved, this study is a hopeful first step in the development of a large scale process for self-cleaning steel production. [less ▲]

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See detail1 Conjoint influence of mind-wandering and sleepiness on task performance
Stawarczyk, David ULg; D'Argembeau, Arnaud ULg

in Journal of Experimental Psychology. Human Perception & Performance (in press)

Recent research suggests that sleepiness and mind-wandering—the experience of thoughts that are both stimulus-independent and task-unrelated—frequently co-occur and are both associated with poorer ... [more ▼]

Recent research suggests that sleepiness and mind-wandering—the experience of thoughts that are both stimulus-independent and task-unrelated—frequently co-occur and are both associated with poorer cognitive functioning. Whether these two phenomena have distinguishable effects on task performance remains unknown, however. To investigate this question, we employed the online experience sampling of mind-wandering episodes and subjective sleepiness during a laboratory task (the Sustained Attention to Response Task; SART), and also assessed mind-wandering frequency and sleep-related disturbances in daily life using self-report questionnaires. The results revealed that the tendency to experience mind-wandering episodes during the SART and daily life was associated with higher levels of daytime sleepiness and sleep-related disturbances. Importantly, however, mind-wandering and sleepiness were independent predictors of SART performance at both the within- and between-individuals levels. These findings demonstrate that, although mind-wandering and sleepiness frequently co-occur, these two phenomena have distinguishable and additive effects on task performance. [less ▲]

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See detailAgeism in Belgium and Burundi: A comparative analysis
Marquet, Manon ULg; Missotten, Pierre ULg; Schroyen, Sarah ULg et al

in Clinical Interventions in Aging (in press)

Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than ... [more ▼]

Background: Recent cross-cultural comparisons between Asian and Western cultures have shown that ageism arises more from the lack of availability of social and economic resources for older adults than from the culture itself. We tested this assumption by conducting a survey among people living in a least-developed country compared with a developed country. Methods: Twenty-seven Belgians living in Belgium, 29 Burundians living in Belgium and 32 Burundians living in Burundi were included in this study. Their attitudes toward older adults were assessed using several self-reported measures. Results: Statistical analyses confirmed that older people are more negatively perceived by Burundians living in Burundi than by Burundians and Belgians living in Belgium, whose attitudes did not differ from each other. Conclusion: Consistent with our hypothesis, our results suggest that the level of development of a country and more particularly the lack of government spending on older people (pension and healthcare systems) may contribute to their younger counterparts perceiving them more negatively. [less ▲]

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See detailGlioblastoma-derived extracellular vesicles induce tumor-supportive phenotypes in monocytic cells
de Vrij, Jeroen; Maas, Sybren; Kwappenberg, Kitty et al

in International Journal of Cancer = Journal International du Cancer (in press)

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See detailThe chlorophyll a fluorescence induction curve in the green microalga Haematococcus pluvialis: Further insight into the nature of the P-S-M fluctuation and its relationship with the "low-wave" phenomenon at steady-state
Fratamico, Anthony ULg; Tocquin, Pierre ULg; Franck, Fabrice ULg

in Photosynthesis Research (in press)

Chlorophyll fluorescence is an information-rich signal which provides an access to the management of light absorbed by PSII. A good example of this is the succession of fast fluorescence fluctuations ... [more ▼]

Chlorophyll fluorescence is an information-rich signal which provides an access to the management of light absorbed by PSII. A good example of this is the succession of fast fluorescence fluctuations during light-induced photosynthetic induction after dark-adaptation. During this period, the fluorescence trace exhibits several inflexion points: O-J-I-P-S-M-T. Thereas the OJIP part of this kinetics has been the subject of many studies, the processes that underly the PSMT transient are less understood. Here, we report an analysis of the PSMT phase in the green microalga Haematococcus pluvialis in terms of electron acceptors and light use by photochemistry, fluorescence and non-photochemical quenching (NPQ). We identify additional sub-phases between P and S delimited by an inflexion point, that we name Q, found in the second time-scale. The P-Q phase expresses a transient photochemical quenching specifically due to alternative electron transport to oxygen. During the transition from Q to S, the NPQ increases and then relaxes during the S-M phase in about 1 min. It is suggested that this transient NPQ observed during induction is a high energy state quenching (qE) dependent the alternative electron transport to molecular oxygen. We further show that this NPQ is of the same nature than the NPQ, known as the low-wave phenomenon, which is transiently observed after a saturating light pulse given at steady-state. In both cases, the NPQ is oxygen-dependent. This NPQ is observed at external pH 6.0, but not at pH 7.5, which seems correlated with faster saturation of the PQ pool at pH 6.0. [less ▲]

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See detailSérialités tintamarresques. Du faux-feuilleton au dictionnaire
Saint-Amand, Denis ULg

in Belphégor : Littérature Populaire et Culture Médiatique (in press)

Parmi les journaux comiques les plus en vue du XIXe siècle, l’hebdomadaire Tintamarre occupe une place de choix. Ses fers de lance, Jean-Louis Commerson et Eugène Vachette s’adjoignent les services ... [more ▼]

Parmi les journaux comiques les plus en vue du XIXe siècle, l’hebdomadaire Tintamarre occupe une place de choix. Ses fers de lance, Jean-Louis Commerson et Eugène Vachette s’adjoignent les services imaginaires de l’écrivain de papier Joseph Citrouillard, qui va rapidement se révéler l’un des contributeurs les plus fidèles du Tintamarre et le sujet de nombreux articles. C’est, dès lors, une double logique sérielle qui se développe autour de Citrouillard, à la fois canular auctorial et antihéros populaire. Cet article interroge les implications et les effets de cette double casquette fantaisiste en ce qui concerne la logique interne du journal et le développement en son sein d’une poétique parodique spécifique, mais également en matière d’institutionnalisation d’une forme de mystification littéraire. [less ▲]

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See detailPerformance characteristics of the VIDAS 25-OH Vitamin D total assay - comparison with four immunoassays and two liquid chromatography-tandem mass spectrometry methods in a multicentric study
Moreau, E; Bächer, S; Mery, S et al

in Clinical Chemistry & Laboratory Medicine (in press)

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other ... [more ▼]

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other immunoassays against the results of two different liquid chromatography/ mass spectrometry methods (LC-MS/MS) standardized to NIST reference materials. Methods: VIDAS® 25-OH Vitamin D Total assay precision, linearity, detection limits and sample matrix comparison were assessed following CLSI guidelines. For method comparison, a total of 150 serum samples ranging from 7 to 92 ng/mL were analyzed by all the methods. Correlation was studied using Passing-Bablok regression and Bland- Altman analysis. The concordance correlation coefficient (CCC) was calculated to evaluate agreement between immunoassays and the reference LC-MS/MS method. In addition, samples containing endogenous 25(OH)D2 were used to assess each immunoassay’s ability to detect this analyte. Pregnancy and hemodialysis samples were used to the study the effect of vitamin D binding protein (DBP) concentration over VIDAS® assay performance. Results: The VIDAS® 25-OH Vitamin D Total assay showed excellent correlation to the LC-MS/MS results (y = 1.01x+0.22 ng/mL, r = 0.93), as obtained from two different sites and distinct LC-MS/MS methods. The limit of quantification was determined at 8.1 ng/mL. Cross-reactivity for 25(OH)D2 was over 80%. At concentrations of 10.5, 26 and 65.1 ng/mL, within-run CVs were 7.9%, 3.6% and 1.7%, while total CVs (between runs, calibrations, lots and instruments) were 16.0%, 4.5% and 2.8%. The VIDAS® performance was not influenced by altered DBP levels, though under-recovery of 25(OH)D as compared to LC-MS/ MS was observed for hemodialysis samples. Conclusions: The VIDAS® 25-OH Vitamin D Total assay is therefore considered suitable for assessment of vitamin D status in clinical routine. Keywords: assay performance; liquid chromatography/ [less ▲]

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See detailCompte rendu de D. van Mal-Maeder, A. Burnier, L. Núñez (éds.): Jeux de voix. Énonciation, intertextualité et intentionnalité dans la littérature antique
Macedo, Gabriel ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (in press)

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See detailNegatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY*
Sautrey, Guillaume; El Khoury, Micheline; Dos Giros, Andrea et al

in Journal of Biological Chemistry (in press)

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See detailState Created Barriers to Exit - The Example of the Acquisition of Alstom by General Electric
Petit, Nicolas ULg

in Competition Policy International (in press)

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See detailTribute to an astronomer: the work of Max Ernst on Wilhelm Tempel
Nazé, Yaël ULg

in Journal for the History of Astronomy (in press)

In 1964-1974, the German artist Max Ernst created, with the help of two friends, a series of works (books, movie, paintings) related to the astronomer Wilhelm Tempel. Mixing actual texts by Tempel and ... [more ▼]

In 1964-1974, the German artist Max Ernst created, with the help of two friends, a series of works (books, movie, paintings) related to the astronomer Wilhelm Tempel. Mixing actual texts by Tempel and artistic features, this series pays homage to the astronomer by recalling his life and discoveries. Moreover, the core of the project, the book Maximiliana or the Illegal Practice of Astronomy, actually depicts the way science works, making this artwork a most original tribute to a scientist. [less ▲]

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailNote a Jacopino del Conte e approfondimenti sulla sua attività giovanile
Geremicca, Antonio ULg

in Proporzioni. Annali della Fondazione Roberto Longhi (in press)

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See detailRevealed preference tests of collectively rational consumption behavior: formulations and algorithms
Talla Nobibon, Fabrice; Cherchye, Laurens; Crama, Yves ULg et al

in Operations Research (in press)

This paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np ... [more ▼]

This paper focuses on revealed preference tests of the collective model of household consumption. We start by showing that the decision problems corresponding to testing collective rationality are {\sc np}-complete. This makes the application of these tests problematic for (increasingly available) large(r) scale data sets. We then present two approaches to overcome this negative result. First, we introduce exact algorithms based on mixed-integer programming ({\sc mip}) formulations of the collective rationality tests, which can be usefully applied to medium sized data sets. Next, we propose simulated annealing heuristics, which allow for efficient testing of the collective model in the case of large data sets. We illustrate our methods by a number of computational experiments based on Dutch labor supply data. [less ▲]

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See detailSU(3) Clebsch-Gordan coefficients at large $N_c$
Stancu, Floarea ULg

in Nuclear Physics A (2016), 945

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic ... [more ▼]

It is argued that several papers where SU(3) Clebsch-Gordan coefficients were calculated in order to describe properties of hadronic systems are, up to a phase convention, particular cases of analytic formulae derived by Hecht in 1965 in the context of nuclear physics. This is valid for irreducible representations with multiplicity one in the corresponding Clebsch-Gordan series. For multiplicity two, Hecht has proposed an alternative which can provide correct $1/N_c$ sub-leading orders in large $N_c$ studies. [less ▲]

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See detailEffects of aging on task- and stimulus-related cerebral attention networks
Kurth, Sophie ULg; Majerus, Steve ULg; Bastin, Christine ULg et al

in Neurobiology of Aging (2016), 44

Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an ... [more ▼]

Interactions between a dorsal attention (DAN) and a ventral attention cerebral network (VAN) have been reported in young participants during attention or short term memory (STM) tasks. Since it remains an under-investigated question, age effects on DAN and VAN activity and their functional balance were explored during performance of a STM task. Older and young groups showed similar behavioral patterns of results. At the cerebral level, DAN activation increased as a function of increasing STM load in both groups, suggesting preserved activity in DAN during healthy aging. Age-related over-recruitment in regions of the DAN in the higher task load raised the question of compensation attempt versus less efficient use of neural resources in older adults. Lesser decrease of VAN activation with increasing load and decreased stimulus-driven activation in the VAN, especially in the higher load, in older participants suggested age-related reduced response in the VAN. However, functional connectivity measures showed that VAN was still functionally connected to the DAN in older participants. [less ▲]

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See detailStatistically Bundled Shewhart Control Charts for Monitoring Delivery Chains Systems
Foster, Earnest; Faraz, Alireza ULg; Heuchenne, Cédric ULg

in European Journal of Industrial Engineering (2016)

Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the ... [more ▼]

Continuous monitoring of Delivery Time variables by means of control charts in a delivery chain is a very recent application of Statistical Process Control (SPC) to the service sector. The aim of the proposed method is to provide supply chain decision makers with an easy to be managed tool monitoring the current functioning state of the delivery chain. The implementation of SPC control charts makes it possible to limit over-corrections to false alarm conditions and to maintain at an acceptable level the safety stock, with a consequent reduction of the overall management costs of the delivery chain. An illustrative example shows the proposed control chart implementation in a real delivery chain. [less ▲]

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See detailHydrocarbon biostimulation and bioaugmentation in organic carbon and clay-rich soils
Masy, Thibaut ULg; Demanèche, Sandrine; Tromme, Olivier et al

in Soil Biology & Biochemistry (2016), 99

Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong ... [more ▼]

Hydrocarbon-contaminated organic carbon-rich clayey soils are challenging for bioremediation stakeholders since the pollutant is heterogeneously distributed and poorly bioavailable due to its strong adsorption on clay and organic particles. In addition, biodegradation rates are restricted by limited diffusion of oxygen and nutrients to hydrocarbon-degrading aerobes. This study assessed the benefits of bioaugmentation with the strain Rhodococcus erythropolis T902.1 versus those from biostimulation and anaerobic natural attenuation in terms of hydrocarbon (HC) degradation efficiency and changes in the bacterial community structure in a diesel-polluted clay-rich soil. Three soil samples with a similar total organic content but with a different HC concentration (0.2, 1.0 and 6.5 g/kg) were compared in a microcosm experiment. Despite a limitation in oxygen transfer, R. erythropolis T902.1 enhanced a greater HC degradation compared to the biostimulation treatment. However, this advantage decreased with time as the proportion of Rhodococci declined from 25% initially to 1% of the global community after 80 days of treatment. Similarly, the alkB gene proportion in bioaugmented soils decreased to levels close to those of biostimulated soils. Consequently, further engineering was suggested to improve the resilience of the inoculum to ensure its long-term presence and activity in such polluted environments. [less ▲]

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See detailStable biofilms of Rhodococcus erythropolis T902.1 in draining pavement structures for runoff water decontamination
Masy, Thibaut ULg; Bertrand, Christelle ULg; Paul-Marie, Xavier et al

in International Biodeterioration & Biodegradation (2016), 112

Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants ... [more ▼]

Permeable Pavement Systems (PPS) are sustainable devices designed to collect, store and treat urban stormwater before its release into the ground. However, this system must sufficiently retain pollutants brought by water runoff in order to comply with the current legislation. This study aims at evaluating the implementation in PPS of a hydrocarbonoclastic bacterium, Rhodococcus erythropolis T902.1, in terms of resilience and improvement of the degrading capacity. First results revealed that this strain could durably colonize the different gravels used in the construction of PPS. A 15-month experience in a real parking area showed that this biofilm remained viable without any replenishment of nutrients or bacteria. During accelerated pollution tests at a pilot scale, the structure bioaugmented with pre-coated biofilms was more efficient than a non-inoculated structure to limit hydrocarbon leaching below 50 μg L−1 and to degrade hydrocarbons adsorbed to the gravels. Over the long term, this innovative assembly should maintain the degrading capacity of PPS and ensure an effective treatment of stormwater before its infiltration into the soil. [less ▲]

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See detailCollaborative Care regarding major depressed patients: A review of guidelines and current practices
Van den Broeck, Kris; Remmen, Roy; Vanmeerbeek, Marc ULg et al

in Journal of Affective Disorders (2016), 200

Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely ... [more ▼]

Major Depressive Disorder (MDD) is a severe and common mental disorder. A growing body of evidence suggests that stepped and/or collaborative care treatment models have several advantages for severely depressed patients and caretakers. However, despite the availability of these treatment strategies and guidance initiatives, many depressive patients are solely treated by the general practitioner (GP), and collaborative care is not common. In this paper, we review a selected set of international guidelines to inventory the best strategies for GPs and secondary mental health care providers to collaborate when treating depressed patients. Additionally, we systematically searched the literature, listing potential ways of cooperation, and potentially supporting tools. We conclude that the prevailing guidelines only include few and rather vague directions regarding the cooperation between GPs and specialised mental health practitioners. Inspiring recent studies, however, suggest that relatively little efforts may result in effective collaborative care and a broader implementation of the guidelines in general. [less ▲]

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See detailAsymptotic properties of free monoid morphisms
Charlier, Emilie ULg; Leroy, Julien ULg; Rigo, Michel ULg

in Linear Algebra & its Applications (2016), 500

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See detailMulti-species measurements of nitrogen isotopic composition r 1 eveal the spatial constraints and 2 biological drivers of ammonium attenuation across a highly contaminated groundwater system
Wells, Naomi S.; Hakoun, Vivien ULg; Brouyère, Serge ULg et al

in Water Research (2016), 98

Groundwater under industrial sites is characterised by heterogeneous chemical mixtures, making it difficult to assess the fate and transport of individual contaminants. Quantifying the in-situ biological ... [more ▼]

Groundwater under industrial sites is characterised by heterogeneous chemical mixtures, making it difficult to assess the fate and transport of individual contaminants. Quantifying the in-situ biological removal (attenuation) of nitrogen (N) is particularly difficult due to its reactivity and ubiquity. Here a multi-isotope approach is developed to distinguish N sources and sinks within groundwater affected by complex industrial pollution. Samples were collected from 70 wells across the two aquifers underlying a historic industrial area in Belgium. Below the industrial site the groundwater contained up to 1000 mg Nl-1 ammonium (NH4 +) and 300 mg N l-1 nitrate (NO3-), while downgradient concentrations decreased to ~1 mg l-1 DIN ([DIN] = [NH4+-N] + [NO3--N] + [NO2--N]). Mean δ1534 N-DIN increased from ~2‰ to +20‰ over this flow path, broadly confirming that biological N attenuation drove the measured concentration decrease. Multi-variate analysis of water chemistry identified two distinct NH4+ sources (δ15N-NH4+ from -14‰ and +5‰) within the contaminated zone of both aquifers. Nitrate dual isotopes co-varied (δ15 N: -3‰ - +60‰; δ18O: 0‰ - +50‰) within the range expected for coupled nitrification and denitrification of the identified sources. The fact that δ15N-NO2- values were 50‰ to 20‰ less than δ15N-NH4+ values in 40 the majority of wells confirmed that nitrification controlled N turnover across the site. However, the fact that δ15N-NO2- was greater than δ15N-NH4+ in wells with the highest [NH4+] shows that an autotrophic NO2- reduction pathway (anaerobic NH4+ oxidation or nitrifier-denitrification) drove N attenuation closest to the contaminant plume. This direct empirical evidence that both autotrophic and heterotrophic biogeochemical processes drive N attenuation in contaminated aquifers demonstrates the power of multiple N isotopes to untangle N cycling in highly complex systems. [less ▲]

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See detailAnalysis of SMOS sea surface salinity data using DINEOF
Alvera Azcarate, Aïda ULg; Barth, Alexander ULg; Parard, Gaëlle ULg et al

in Remote Sensing of Environment (2016), 180

n analysis of daily Sea Surface Salinity (SSS) at 0.15 ° × 0.15° spatial resolution from the Soil Moisture and Ocean Salinity (SMOS) satellite mission using DINEOF (Data Interpolating Empirical Orthogonal ... [more ▼]

n analysis of daily Sea Surface Salinity (SSS) at 0.15 ° × 0.15° spatial resolution from the Soil Moisture and Ocean Salinity (SMOS) satellite mission using DINEOF (Data Interpolating Empirical Orthogonal Functions) is presented. DINEOF allows reconstructing missing data using a truncated EOF basis, while reducing the amount of noise and errors in geophysical datasets. This work represents a first application of DINEOF to SMOS SSS. Results show that a reduction of the error and the amount of noise is obtained in the DINEOF SSS data compared to the initial SMOS SSS data. Errors associated to the edge of the swath are detected in 2 EOFs and effectively removed from the final data, avoiding removing the data at the edges of the swath in the initial dataset. The final dataset presents a centered root mean square error of 0.2 in open waters when comparing with thermosalinograph data at their original spatial and temporal resolution. Constant biases present near land masses, large scale biases and latitudinal biases cannot be corrected with DINEOF because persistent signals are retained in high order EOFs, and therefore these need to be corrected separately. The signature of the Douro and Gironde rivers is detected in the DINEOF SSS. The minimum SSS observed in the Gironde plume corresponds to a flood event in June 2013, and the shape and size of the Douro river shows a good agreement with chlorophyll-a satellite data. These examples show the capacity of DINEOF to remove noise and provide a full SSS dataset at a high temporal and spatial resolution with reduced error, and the possibility to retrieve physical signals in zones with high initial errors. [less ▲]

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See detailA simple calibration approach based on film-casting for confocal Raman microscopy to support the development of a Hot-Melt Extrusion process
Netchacovitch, Lauranne ULg; Thiry, Justine ULg; De Bleye, Charlotte ULg et al

in Talanta (2016), 154

When developing a new formulation, the development, calibration and validation steps of analytical methods based on vibrational spectroscopy are time-consuming. For each new formulation, real samples must ... [more ▼]

When developing a new formulation, the development, calibration and validation steps of analytical methods based on vibrational spectroscopy are time-consuming. For each new formulation, real samples must be produced and a “reference method” must be used in order to determine the Active Pharmaceutical Ingredient (API) content of each sample. To circumvent this issue, the paper presents a simple approach based on the film-casting technique used as a calibration tool in the framework of hot-melt extrusion process. Confocal Raman microscopic method was successfully validated for the determination of itraconazole content in film-casting samples. Then, hot-melt extrusion was carried out to produce real samples in order to confront the results obtained with confocal Raman microscopy and Ultra High Performance Liquid Chromatography (UHPLC). The agreement between both methods was demonstrated using a comparison study based on the Bland and Altman’s plot. [less ▲]

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See detailPerformance et Innovation en PME: une relation à questionner
Ajzen, Michel; Rondeaux, Giseline ULg; Pichault, François ULg et al

in Revue Internationale P.M.E. (2016), 29(2),

Noting that in management science, management policies would have all, the ultimate ambition of contributing to company performance and the innovative capacity of a company would be a sine qua non of this ... [more ▼]

Noting that in management science, management policies would have all, the ultimate ambition of contributing to company performance and the innovative capacity of a company would be a sine qua non of this performance, this article shows that (if) these two concepts refer to disparate content; (ii) the performance is primarily measured by distanced indicators (financial); (iii) the nature of the interdependence between innovation and performance is not unequivocal. Considering the weight of contextual variables, we show the interest to adopt a broader vision of concepts of innovation and performance in SMEs, capitalizing on the diversity of performance and innovation characterizations, and adopting an agnostic approach establishing no a priori link between them. This article proposes to broaden the concepts of innovation and performance by mobilizing indicators specific to SMEs and outlines a methodology to measure and weigh them as well as to provide researchers with tools to better understand the interactions between these variables. In doing so, we contribute to a critical approach of de-naturalization to emancipate SMEs and, more broadly, public and regulatory authorities, from narrow performative standards. [less ▲]

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See detailScreening study of SFC critical method parameters for the determination of pharmaceutical compounds
Dispas, Amandine ULg; Lebrun, Pierre ULg; Sacre, Pierre-Yves ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2016), 125

Nowadays, supercritical fluid chromatography is commonly presented as a promising alternative technique in the field of separation sciences. Nevertheless the selection of chromatographic conditions and ... [more ▼]

Nowadays, supercritical fluid chromatography is commonly presented as a promising alternative technique in the field of separation sciences. Nevertheless the selection of chromatographic conditions and sample preparation of pharmaceutical compounds remain a challenge and peak distortion was previously highlighted. The main objective of the present work was to evaluate the impact of different critical method parameters (CMPs), i.e. stationary phase, mobile phase composition and injection solvent nature. The experiments were performed considering two groups of antimalarial molecules: one group with neutral/apolar compounds and the other one with salt form of polar compounds. In this context, another objective was to propose a suitable sample solvent for quantitative analysis. The interest of new generation stationary phase to obtain good peak shape and the interest to tune the mobile phase composition were demonstrated. During this study, design of experiments and desirability function approach enabled to highlight optimal chromatographic conditions in order to maximise peak capacity and to get acceptable value of symmetry factor. Regarding sample injection solvent composition, some counterintuitive results were observed: solvents closer to the mobile phase polarity (i.e heptane or 2-propanol/heptane mixture) did not provide best results in terms of peak symmetry. In addition, acetonitrile and short aliphatic alcohols offered an interesting alternative as injection solvent: toxicity of solvents used is clearly reduced and better quantitative performances could be expected while keeping high peak capacity and symmetric sharp peaks. Finally, the quantitative performances were evaluated by the method validation for the quantitative determination of quinine sulfate in a pharmaceutical formulation. These better understandings on critical method parameters led SFC to be an even more promising technique in the field of the analysis of pharmaceutical compounds. [less ▲]

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See detailHydrogeological assessment of non-linear underground enclosures
Pujades, Estanislao ULg; Jurado Elices, Anna ULg; Carrera, Jesus et al

in Engineering Geology (2016), 207

Excavations below the water table are usually undertaken by combining the protection of retaining walls with dewatering by pumping wells. Severe difficulties may arise if the retaining walls have defects ... [more ▼]

Excavations below the water table are usually undertaken by combining the protection of retaining walls with dewatering by pumping wells. Severe difficulties may arise if the retaining walls have defects. Therefore, their state must be determined and, if needed, the defects repaired or the dewatering system redesigned. The state of underground retaining walls can be evaluated using hydrogeological methods, but these methods are well-established only for linear excavations. The objective of this work is to propose a procedure to evaluate the state of non-linear underground enclosures by analyzing the groundwater response to pumping inside the enclosure. The proposed method, which is based on diagnostic plots (derivative of drawdown with respect to the logarithm of time), allows (1) determining if an underground non-linear enclosure has isolated openings or numerous defects and (2) computing its effective conductance or effective hydraulic conductivity. The methodology is tested with data collected during the excavation of a shaft required for the construction of the high speed train (HST) tunnel in Barcelona, Spain. The procedure can be applied using the wells drilled for dewatering. Although a test before the excavation is recommended to evaluate the underground retaining walls (Watertightness Assessment Test), the method can be applied using data collected at the beginning of the dewatering stage. [less ▲]

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See detailLaboratory idenification of anaerobic bacteria isolated on Clostridium difficile selective medium
Rodriguez Diaz, Cristina ULg; Warszawski, Nathalie; Korsak Koulagenko, Nicolas ULg et al

in Acta Microbiologica et Immunologica Hungarica (2016)

Despite increasing interest in the bacterium, the methodology for Clostridium difficile recovery has not yet been standardised. Cycloserine cefoxitin fructose taurocholate (CCFT) has historically been the ... [more ▼]

Despite increasing interest in the bacterium, the methodology for Clostridium difficile recovery has not yet been standardised. Cycloserine cefoxitin fructose taurocholate (CCFT) has historically been the most used medium for C. difficile isolation from human, animal, environmental and food samples, and presumptive identification is usually based on colony morphologies. However, CCFT is not totally selective. This study describes the recovery of 24 bacteria species belonging to 10 different genera other than C. difficile, present in the environment and foods of a retirement establishment that were not inhibited in the C. difficile selective medium. These findings provide insight for further environmental and food studies as well as for isolation of C. difficile on supplemented CCFT. [less ▲]

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See detailExplaining the diversity of motivations behind community renewable energy
Bauwens, Thomas ULg

in Energy Policy (2016), 93

Community-based renewable energy initiatives may be important actors in the transition toward low-carbon energy systems. In turn, stimulating investments in renewable energy production at the community ... [more ▼]

Community-based renewable energy initiatives may be important actors in the transition toward low-carbon energy systems. In turn, stimulating investments in renewable energy production at the community level requires a better understanding of investors’ motives. This paper aims to study the heterogeneity of motivations that drive individuals to participate in community renewable energy projects and the underlying explanatory factors behind this, as well as the implications for their level of engagement in initiatives. Based on quantitative data from an original survey conducted with two renewable energy cooperatives in Flanders, the statistical analysis shows that cooperative members should not be considered as one homogeneous group. Several categories of members with different motives and levels of engagement can be distinguished. This heterogeneity is explained by contrasts in terms of institutional settings, spatial patterns and attitudes to the diffusion of institutional innovations. Regarding policy implications, the findings suggest that this heterogeneity should be taken into account in designing more effective supporting policies to stimulate investments at the community level. The activation of social norms is also shown to be a promising mechanism for triggering investment decisions, although the implications of its interplay with economic incentives should be further explored. [less ▲]

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See detailThe scent of love: how important are semiochemicals in the sexual behavior of lady beetles?
Fassotte, Bérénice ULg; Francis, Frédéric ULg; Verheggen, François ULg

in Journal of Pest Science (2016), 89(2), 347-358

Chemical signals are involved in the courtship behavior of many invertebrate and vertebrate species. Lady beetles are no exception to this rule; a significant number of published reports highlight the ... [more ▼]

Chemical signals are involved in the courtship behavior of many invertebrate and vertebrate species. Lady beetles are no exception to this rule; a significant number of published reports highlight the role of cuticular chemicals involved in the reproduction of lady beetles, including gender recognition. Recent data have also demonstrated the presence of a volatile female sex pheromone that facilitates male attraction in some species. Here, we present a synthetic overview of the current knowledge about the sexual behavior of lady beetles and associated chemicals for which the function and identification have been provided. Because lady beetles are often reared as biological control agents, the chemical cues involved in their sexual behavior could be used as components in integrated management approaches against soft-bodied hemipterans. In conclusion, this review provides new perspectives and potential developments for sustainable insect management mainly based on the semiochemicals involved in the sexual behavior of lady beetles. A better understanding of these chemical signals would help maximize their presence in areas where their predatory behavior is requested, as a result of the application of formulations inducing behavioral manipulation. [less ▲]

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See detailAn Exact Method for Designing Shewhart X ̅ and S2 Control Charts to Guarantee the In-Control Performance
Faraz, Alireza ULg; Heuchenne, Cédric ULg

in Journal of Quality Technology (2016)

The in-control performance of the Shewhart X ̅ and S2 control charts with estimated in-control parameters has been evaluated by a number of authors. Results indicate an unrealistically large amount of ... [more ▼]

The in-control performance of the Shewhart X ̅ and S2 control charts with estimated in-control parameters has been evaluated by a number of authors. Results indicate an unrealistically large amount of Phase I data is needed to have the desired in-control average run length (ARL) value in Phase II. To overcome this problem, it has been recommended that the control limits be adjusted based on a bootstrap method to guarantee that the in-control ARL is at least a specified value with a certain specified probability. In our paper we present simple formulas for the required control limits so that practitioners do not have to use the bootstrap method. An assumption of normality is required. The advantage of our proposed method is in its simplicity; there is no bootstrapping and the control chart constants do not depend on the Phase I sample data. [less ▲]

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See detailDoes sector-specific experience matter? The case of European higher education ministers
Jacqmin, Julien ULg; Lefebvre, Mathieu ULg

in Research Policy (2016), 45(5), 987998

This paper looks at the relationship between higher education ministers and the performance of the sector that they govern. Using an original panel dataset with the characteristics of European higher ... [more ▼]

This paper looks at the relationship between higher education ministers and the performance of the sector that they govern. Using an original panel dataset with the characteristics of European higher education ministers, we find that having a past experience in the sector leads to a higher level of performance, as measured by ranking data. Making a parallel with the literature about the impact of education on the educated, we discuss potential explanations behind the impact of this on-the-job learning experience. As we find that this characteristic has no impact on the spendings of the sector, we argue that this academic experience makes them more prone to introduce adequate reforms that makes the sector more attractive for top-researchers. Furthermore, we find that this result is driven by ministers with both sector-specific and electoral experience, the latter measured by a successful election at the regional or national level. This tends to show that political credibility should not be overshadowed by the importance of the sector-specific experience of ministers. [less ▲]

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See detailManagement of relapsed multiple myeloma: Recommendations of the international myeloma working group
Laubach, J.; Garderet, L.; Mahindra, A. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2016), 30(5), 1005-1017

The prognosis for patients multiple myeloma (MM) has improved substantially over the past decade with the development of new, more effective chemotherapeutic agents and regimens that possess a high level ... [more ▼]

The prognosis for patients multiple myeloma (MM) has improved substantially over the past decade with the development of new, more effective chemotherapeutic agents and regimens that possess a high level of anti-tumor activity. In spite of this important progress, however, nearly all MM patients ultimately relapse, even those who experience a complete response to initial therapy. Management of relapsed MM thus represents a vital aspect of the overall care for patients with MM and a critical area of ongoing scientific and clinical research. This comprehensive manuscript from the International Myeloma Working Group provides detailed recommendations on management of relapsed disease, with sections dedicated to diagnostic evaluation, determinants of therapy, and general approach to patients with specific disease characteristics. In addition, the manuscript provides a summary of evidence from clinical trials that have significantly impacted the field, including those evaluating conventional dose therapies, as well as both autologous and allogeneic stem cell transplantation. Specific recommendations are offered for management of first and second relapse, relapsed and refractory disease, and both autologous and allogeneic transplant. Finally, perspective is provided regarding new agents and promising directions in management of relapsed MM. [less ▲]

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See detailUse of Estetrol with other Steroids for Attenuation of Neonatal Hypoxic-Ischemic brain injury:to combine or not to combine?
Tskitishvili, Ekaterine ULg; Pequeux, Christel ULg; Munaut, Carine ULg et al

in Oncotarget (2016)

Estetrol (E4), estradiol (E2) and progesterone (P4) have important antioxidative and neuroprotective effects in neuronal system. We aimed to study the consequence of combined steroid therapy in neonatal ... [more ▼]

Estetrol (E4), estradiol (E2) and progesterone (P4) have important antioxidative and neuroprotective effects in neuronal system. We aimed to study the consequence of combined steroid therapy in neonatal hypoxic-ischemic encephalopathy (HIE). In vitro the effect of E4 combined with other steroids on oxidative stress and the cell viability in primary hippocampal cultures was evaluated by lactate dehydrogenase and cell survival assays. In vivo neuroprotective and therapeutic efficacy of E4 combined with other steroids was studied in HIE model of immature rats. The rat pups rectal temperature, body and brain weights were evaluated. The hippocampus and the cortex were investigated by histo/immunohistochemistry: intact cell number counting, expressions of markers for early gray matter lose, neuro- and angiogenesis were studied. Glial fibrillary acidic protein was evaluated by ELISA in blood samples. In vitro E4 and combinations of high doses of E4 with P4 and/or E2 significantly diminished the LDH activity and upregulated the cell survival. In vivo pretreatment or treatment by different combinations of E4 with other steroids had unalike effects on body and brain weight, neuro- and angiogenesis, and GFAP expression in blood. The combined use of E4 with other steroids has no benefit over the single use of E4. [less ▲]

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See detailDelanaye P, Pottel H. Kidney-Failure Risk Projection for the Living Kidney-Donor candidate.
DELANAYE, Pierre ULg; Glassock, Richard

in New England Journal of Medicine (2016), 374(21), 2093-2094

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See detailHow Bees Deter Elephants: Beehive Trials with Forest Elephants (Loxodonta africana cyclotis) in Gabon
Ngama, Steeve ULg; Korte, Lisa; Bindelle, Jérôme ULg et al

in PLoS ONE (2016), 11(5), 12

In Gabon, like elsewhere in Africa, crops are often sources of conflict between humans and wildlife. Wildlife damage to crops can drastically reduce income, amplifying poverty and creating a negative ... [more ▼]

In Gabon, like elsewhere in Africa, crops are often sources of conflict between humans and wildlife. Wildlife damage to crops can drastically reduce income, amplifying poverty and creating a negative perception of wild animal conservation among rural people. In this context, crop-raiding animals like elephants quickly become “problem animals”. To deter elephants from raiding crops beehives have been successfully employed in East Africa; however, this method has not yet been tested in Central Africa. We experimentally examined whether the presence of Apis mellifera adansonii, the African honey bee species present in Central Africa, deters forest elephants (Loxodonta Africana cyclotis) from feeding on fruit trees. We show for the first time that the effectiveness of beehives as deterrents of elephants is related to bee activity. Empty hives and those housing colonies of low bee activity do not deter elephants all the time; but beehives with high bee activity do. Although elephant disturbance of hives does not impede honey production, there is a tradeoff between deterrence and the quantity of honey produced. To best achieve the dual goals of deterring elephants and producing honey colonies must maintain an optimum activity level of 40 to 60 bee movements per minute. Thus, beehives colonized by Apis mellifera adansonii bees can be effective elephant deterrents, but people must actively manage hives to maintain bee colonies at the optimum activity level. [less ▲]

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See detailOrbital, spin state and thermophysical characterization of near-Earth asteroid (3200) Phaethon
Hanus, Josef; Delbo, Marco; Vokrouhlický, D. et al

in Astronomy and Astrophysics (2016)

The near-Earth asteroid (3200) Phaethon is an intriguing object: its perihelion is only at 0.14 au and is associated with the Geminid meteor stream. We aim to use all available disk-integrated optical ... [more ▼]

The near-Earth asteroid (3200) Phaethon is an intriguing object: its perihelion is only at 0.14 au and is associated with the Geminid meteor stream. We aim to use all available disk-integrated optical data to derive reliable convex shape model of Phaethon. By interpreting the available space- and ground-based thermal infrared data and Spitzer spectra using a thermophysical model, we also aim to further constrain its size, thermal inertia, and visible geometric albedo. We apply the convex inversion method to the new optical data obtained by six instruments together with the already existing observations. The convex shape model is then used as an input for the thermophysical modeling. We also study the long-term stability of Phaethon’s orbit and spin axis by a numerical orbital and rotation-state integrator We present a new convex shape model and rotational state of Phaethon – sidereal rotation period of 3.603958(2) h and ecliptic coordinates of the preferred pole orientation of (319◦ , −39◦) with a 5◦ uncertainty. Moreover, we derive its size (D=5.1±0.2 km), thermal inertia (Γ=600±200 J m-2s -1/2K -1), geometric visible albedo (pV=0.122±0.008), and estimate the macroscopic surface roughness. We also find that the Sun illumination at the perihelion passage during past thousands of years is not connected to a specific area on the surface implying non-preferential heating. [less ▲]

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See detailA New Approach for the Characterization of Organic Residues from Stone Tools Using GC×GC-TOFMS
Perrault, Katelynn ULg; Stefanuto, Pierre-Hugues ULg; Dubois, Lena ULg et al

in Separations (2016), 3(2), 16

Headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) have traditionally been used, in combination with other analyses, for the chemical characterization of ... [more ▼]

Headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) have traditionally been used, in combination with other analyses, for the chemical characterization of organic residues recovered from archaeological specimens. Recently in many life science fields, comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS) has provided numerous benefits over GC-MS. This study represents the first use of HS-SPME-GC×GC-TOFMS to characterize specimens from an experimental modern reference collection. Solvent extractions and direct analyses were performed on materials such as ivory, bone, antlers, animal tissue, human tissue, sediment, and resin. Thicker film column sets were preferred due to reduced column overloading. The samples analyzed by HS-SPME directly on a specimen appeared to give unique signatures and generally produced a higher response than for the solvent-extracted residues. A non-destructive screening approach of specimens may, therefore, be possible. Resin and beeswax mixtures prepared by heating for different lengths of time appeared to provide distinctly different volatile signatures, suggesting that GC×GC-TOFMS may be capable of differentiating alterations to resin in future studies. Further development of GC×GC-TOFMS methods for archaeological applications will provide a valuable tool to uncover significant information on prehistoric technological changes and cultural behavior. [less ▲]

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See detailEfficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial.
LAGNY, Marc-Gilbert ULg; GOTHOT, André ULg; HANS, Grégory ULg et al

in Perfusion (2016)

Efficacy of the RemoweLL cardiotomy reservoir for Fat and Leucocyte removal from shed mediastinal blood: a randomized controlled trial. ABSTRACT (176 words) Introduction Re-transfusion of lipid particles ... [more ▼]

Efficacy of the RemoweLL cardiotomy reservoir for Fat and Leucocyte removal from shed mediastinal blood: a randomized controlled trial. ABSTRACT (176 words) Introduction Re-transfusion of lipid particles and activated leucocytes with shed mediastinal blood (SMB) can aggravate cardiopulmonary bypass-associated inflammation and increase the embolic load. This study evaluated the fat and leucocyte removal capacity of the RemoweLL cardiotomy reservoir. Methods Forty-five patients undergoing elective on-pump cardiac surgery were randomly allocated to filtration of SMB using the RemoweLL or the Admiral cardiotomy reservoir. The primary outcome was the drop in leucocytes and lipid particles obtained with the two filters. The effect of the filters on other blood cells and inflammatory mediators such as myeloperoxidase (MPO) was also assessed. Results The RemoweLL cardiotomy filter removed 16.5 % of the leucocytes (P < 0.001) while no significant removal of leucocytes was observed with the Admiral (P = 0.48). The percentage reductions in lipid particles were similar in the two groups (26% vs 23 %, P = 0.2). Both filters similarly affected the level of MPO (P = 0.71). Discussion The RemoweLL filter more effectively removed leucocytes from SMB than the Admiral. It offered no advantage in term of lipid particle clearance. [less ▲]

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See detailSpiral waves triggered by shadows in transition disks
Montesinos, Matias; Pérez, Sebastian; Casassus, Simon et al

in Astrophysical Journal Letters (2016)

Circumstellar asymmetries such as central warps have recently been shown to cast shadows on outer disks. We investigate the hydrodynamical consequences of such variable illumination on the outer regions ... [more ▼]

Circumstellar asymmetries such as central warps have recently been shown to cast shadows on outer disks. We investigate the hydrodynamical consequences of such variable illumination on the outer regions of a transition disk, and the development of spiral arms. Using 2D simulations, we follow the evolution of a gaseous disk passively heated by the central star, under the periodic forcing of shadows with an opening angle of $\sim$28$^\circ$. With a lower pressure under the shadows, each crossing results in a variable azimuthal acceleration, which in time develops into spiral density waves. Their pitch angles evolve from $\Pi \sim 15^\circ-22^\circ$ at the onset, to $\sim$11$^\circ$-14$^\circ$, over $\sim$65~AU to 150~AU. Self-gravity enhances the density contrast of the spiral waves, as also reported previously for spirals launched by planets. Our control simulations with unshadowed irradiation do not develop structures, except for a different form of spiral waves seen at later times only in the gravitationally unstable control case. Scattered light predictions in the $H$-band show that such illumination spirals should be observable. We suggest that spiral arms in the case-study transition disk HD~142527 could be explained as a result of shadowing from the tilted inner disk. [less ▲]

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See detailEnhancing Spatio-Temporal Identity: States of Existence and Presence
Hallot, Pierre ULg; Billen, Roland ULg

in International Journal of Geo-Information (2016), 5(62),

This work presents a new approach that aims to characterize the spatio-temporal relationships that exist between geographical objects that are absent or non-existent at the moment of analysis. First, we ... [more ▼]

This work presents a new approach that aims to characterize the spatio-temporal relationships that exist between geographical objects that are absent or non-existent at the moment of analysis. First, we would like to propose a formal analysis of the spatio-temporal states of presence and existence of a geographical object. We will then use a combination of these states in order to define a set of life and motion configurations. The model developed then serves as a formal basis for the realization of a series of spatio-temporal queries based on an analysis of patterns in the succession of spatio-temporal states. The entire approach is then demonstrated by using the example of the organization of a scientific conference by defining the spatio-temporal relationships between the conference participants. The research methodology is finally compared with a real dataset taken from a geolocalized social network to show the efficiency of this type of management. [less ▲]

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See detailLa médecine du futur en question(s): les objets connectés
Coucke, Philippe ULg

in Healthcare Executive (2016)

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See detailModelling the mortality of Hylotrupes bajulus (L.) larvae exposed to anoxic treatment for disinfestation of wooden art objects
de Streel, Géraud; Henin, Jean-Marc; Bogaert, Patrick et al

in Wood Science & Technology (2016)

Experiments were conducted to quantify the effect of several variables on the mortality of insects exposed to an anoxic treatment in order to generate a model linking mortality to these variables. This ... [more ▼]

Experiments were conducted to quantify the effect of several variables on the mortality of insects exposed to an anoxic treatment in order to generate a model linking mortality to these variables. This study aims to explore the possible interest of using such a model to determine the characteristics of treatment (especially duration) needed to guarantee insect mortality with a given level of probability. Trials were performed on Hylotrupes bajulus larvae, which is a widespread species known for its high tolerance to anoxic conditions. The studied variables are the initial mass of the larvae, the treatment temperature (21, 30 and 40 C), the treatment duration (four durations for each temperature tested) and whether the larva is held in wood or in a petri dish (directly exposed to anoxic atmosphere) during the experiment. It was found that, while the last variable is not correlated with mortality, treatment duration and temperature are significantly and positively correlated with it. Larvae with higher body mass were also shown to have a better resistance to the treatment. Based on these results, a model including insect initial mass, treatment temperature and duration, together with the interaction between these two variables, was determined. This relatively simple model appeared to be a useful tool in overcoming the difficulty in defining the modalities for anoxic treatment in order to reach a given level of mortality. [less ▲]

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See detailA new classification of earthquake-induced landslide event sizes based on seismotectonic, topographic, climatic and geologic factors
Havenith, Hans-Balder ULg; Torgoev, Almazbek ULg; Braun, Anika et al

in Geoenvironmental Disasters (2016), 3(6), 2-24

Background This paper reviews the classical and some particular factors contributing to earthquake-triggered landslide activity. This analysis should help predict more accurately landslide event sizes ... [more ▼]

Background This paper reviews the classical and some particular factors contributing to earthquake-triggered landslide activity. This analysis should help predict more accurately landslide event sizes, both in terms of potential numbers and affected area. It also highlights that some occurrences, especially those very far from the hypocentre/activated fault, cannot be predicted by state-of-the-art methods. Particular attention will be paid to the effects of deep focal earthquakes in Central Asia and to other extremely distant landslide activations in other regions of the world (e.g. Saguenay earthquake 1988, Canada). Results The classification of seismically induced landslides and the related ‘event sizes’ is based on five main factors: ‘Intensity’, ‘Fault factor’, ‘Topographic energy’, ‘Climatic background conditions’, ‘Lithological factor’. Most of these data were extracted from papers, but topographic inputs were checked by analyzing the affected region in Google Earth. The combination and relative weight of the factors was tested through comparison with well documented events and complemented by our studies of earthquake-triggered landslides in Central Asia. The highest relative weight (6) was attributed to the ‘Fault factor’; the other factors all received a smaller relative weight (2–4). The high weight of the ‘Fault factor’ (based on the location in/outside the mountain range, the fault type and length) is strongly constrained by the importance of the Wenchuan earthquake that, for example, triggered far more landslides in 2008 than the Nepal earthquake in 2015: the main difference is that the fault activated by the Wenchuan earthquake created an extensive surface rupture within the Longmenshan Range marked by a very high topographic energy while the one activated by the Nepal earthquake ruptured the surface in the frontal part of the Himalayas where the slopes are less steep and high. Finally, the calibrated factor combination was applied to almost 100 other earthquake events for which some landslide information was available. This comparison revealed the ability of the classification to provide a reasonable estimate of the number of triggered landslides and of the size of the affected area. According to this prediction, the most severe earthquake-triggered landslide event of the last one hundred years would actually be the Wenchuan earthquake in 2008 followed by the 1950 Assam earthquake in India – considering that the dominating role of the Wenchuan earthquake data (including the availability of a complete landslide inventory) for the weighting of the factors strongly influences and may even bias this result. The strongest landslide impacts on human life in recent history were caused by the Haiyuan-Gansu earthquake in 1920 – ranked as third most severe event according to our classification: its size is due to a combination of high shaking intensity, an important ‘Fault factor’ and the extreme susceptibility of the regional loess cover to slope failure, while the surface morphology of the affected area is much smoother than the one affected by the Wenchuan 2008 or the Nepal 2015 earthquakes. Conclusions The main goal of the classification of earthquake-triggered landslide events is to help improve total seismic hazard assessment over short and longer terms. Considering the general performance of the classification-prediction, it can be seen that the prediction either fits or overestimates the known/observed number of triggered landslides for a series of earthquakes, while it often underestimates the size of the affected area. For several events (especially the older ones), the overestimation of the number of landslides can be partly explained by the incompleteness of the published catalogues. The underestimation of the extension of the area, however, is real – as some particularities cannot be taken into account by such a general approach: notably, we used the same seismic intensity attenuation for all events, while attenuation laws are dependent on regional tectonic and geological conditions. In this regard, it is likely that the far-distant triggering of landslides, e.g., by the 1988 Saguenay earthquake (and the related extreme extension of affected area) is due to a very low attenuation of seismic energy within the North American plate. Far-distant triggering of landslides in Central Asia can be explained by the susceptibility of slopes covered by thick soft soils to failure under the effect of low-frequency shaking induced by distant earthquakes, especially by the deep focal earthquakes in the Pamir – Hindukush seismic region. Such deep focal and high magnitude (> > 7) earthquakes are also found in Europe, first of all in the Vrancea region (Romania). For this area as well as for the South Tien Shan we computed possible landslide event sizes related to some future earthquake scenarios. [less ▲]

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See detailIntegrating Corporate Sustainability Assessment, Management Accounting, Control, and Reporting
Maas, Karen; Schaltegger, Stefan; Crutzen, Nathalie ULg

in Journal of Cleaner Production (2016)

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See detailMechanisms involved in pearlfish resistance to holothuroid toxins
Brasseur, Lola; Parmentier, Eric ULg; Caulier, Guillaume et al

in Marine Biology (2016), 163(129), 1-14

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See detailPlatelet Rich Plasma for Treating Chronic Tendinopathy
Kaux, Jean-François ULg

in Aspetar Sports Medicine Journal (2016), 4(1), 118-122

Tendinopathy is a major problem in medicine and sports traumatology. It is due, inter alia, to mechanical overload. It remains a challenge for the medical world to the extent that its frequent resistance ... [more ▼]

Tendinopathy is a major problem in medicine and sports traumatology. It is due, inter alia, to mechanical overload. It remains a challenge for the medical world to the extent that its frequent resistance to conventional treatments never promises the patient a favourable response following therapeutic management. The development of platelet-rich plasma (PRP) is a new hope when therapeutic treatments such as NSAIDs, corticosteroid injections, eccentric rehabilitation, shock waves, etc. have shown their limits. Furthermore, since January 2011, it is no longer included on the list of doping substances (http://www.wada-ama.org/). Indeed, platelets contain various growth factors (PDGF, TGF-β, FGF, VEGF, HGF, IGF-1) which participate to the tendon healing process. PRP is obtained by centrifugation of autologous blood to obtain a platelet concentration greater than that of the blood, which varies according to the production method. PRP also contains a variable amount of lymphocytes and erythrocytes that can have a detrimental effect on wound healing. Currently, there is no formal consensus regarding the production method or the biological composition of PRP. Many laboratory studies (in vitro and/or on animal) emphasize the acceleration of the healing tendon process after injection of PRP, each growth factor exerting a specific action during healing. PRP would cause the proliferation, migration and differentiation of cells derived from circulation, improving the initial phase of the tendon healing. This anabolic process initiates the type I collagen synthesis. Although currently the effectiveness of PRP on tendon healing in vitro or in animals seems to be confirmed, clinical studies are currently still controversial. In addition, there is still only a limited number of randomized and controlled studies reviewing PRP for treating tendinopathy. However, it seems that PRP can be efficient to treat lateral epicondylitis, patellar tendinopathies and plantar fasciitis, even if the level of proofs remains low. Up to now there is not enough proofs concerning the use of PRP to treat rotator cuff or Achilles tendinopathies. More randomized, controlled and blinded studies remain needed. In conclusion, experimentally, PRP, through the local release of various growth factors stimulates tendon healing. This therapy could optimize the healing of pathological human tendons. PRP should be analysed to see whether it improves tendon healing in both humans and animals through other randomized controlled trials. [less ▲]

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See detailTrophic plasticity of Antarctic echinoids under contrasted environmental conditions
Michel, Loïc ULg; David, Bruno; Dubois, Philippe et al

in Polar Biology (2016), 39(5), 913-923

Echinoids are common members of Antarctic zoobenthos, and different groups can show important trophic diversity. As part of the ANT-XXIX/3 cruise of RV Polarstern, trophic plasticity of sea urchins was ... [more ▼]

Echinoids are common members of Antarctic zoobenthos, and different groups can show important trophic diversity. As part of the ANT-XXIX/3 cruise of RV Polarstern, trophic plasticity of sea urchins was studied in three neighbouring regions (Drake Passage, Bransfield Strait and Weddell Sea) featuring several depth-related habitats offering different trophic environments to benthic consumers. Three families with contrasting feeding habits (Cidaridae, Echinidae and Schizasteridae) were studied. Gut content examination and stable isotopes ratios of C and N suggest that each of the studied families showed a different response to variation in environmental and food conditions. Schizasteridae trophic plasticity was low, and these sea urchins were bulk sediment feeders relying on sediment-associated organic matter in all regions and/or depth-related habitats. Cidaridae consumed the most animal-derived material. Their diet varied according to the considered area, as sea urchins from Bransfield Strait relied mostly on living and/or dead animal material, while specimens from Weddell Sea fed on a mixture of dead animal material and other detritus. Echinidae also showed important trophic plasticity. They fed on various detrital items in Bransfield Strait, and selectivity of ingested material varied across depth-related habitats. In Weddell Sea, stable isotopes revealed that they mostly relied on highly 13C-enriched food items, presumably microbially-reworked benthic detritus. The differences in adaptive strategies could lead to family-specific responses of Antarctic echinoids to environmental and food-related changes. [less ▲]

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See detailLes paysans sans terre et REDD+ en RDC : les logiques locales faces aux interventions internationales
Reyniers, Camille; Karsenty, Alain; Vermeulen, Cédric ULg

in Cahiers africains (2016), 87

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See detailL’institutionnalisation du droit international (1869-1873). Les réseaux internationaux de Gustave Rolin-Jaequemyns
Genin, Vincent ULg

in Journal of the History of International Law / Revue d'Histoire du Droit International (2016), 18(2-3), 181-196

This article deals with a phenomenon which appears in a particular context: the institutionalisation of international law between 1869 (creation of the Revue de droit international et de législation ... [more ▼]

This article deals with a phenomenon which appears in a particular context: the institutionalisation of international law between 1869 (creation of the Revue de droit international et de législation comparée) and 1873 (birth of the Institut de Droit International), through the international networks of the Belgian lawyer Gustave Rolin-Jaequemyns. He was close to Pasquale Mancini, John Westlake, James Lorimer, Franz Von Holtzendorff, but also to the least-known Michael Corr-Van der Maeren, a publicist. Until this period of crystallisation this field was not structured and represented an aggregate of individualities. What can we say about such a process of institutionalisation on the basis of unpublished archives? The history of international law, until today, especially studied by lawyers, was very neglected by historians, whose methods and sources are complementary to those of the lawyer. Our contribution wishes to contribute to the development of a history of international law written by historians. [less ▲]

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See detailGarric (Henri), dir., L’Engendrement des images en bande dessinée
Crucifix, Benoît ULg

in Textyles : Revue des Lettres Belges de Langue Française (2016), (48), 172-174

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See detailRaisonnement analogique, connaissance relationnelle et troubles du langage.
Krzemien, Magali ULg

in Glossa (2016), 119

The construction grammar theory claims that language development is achieved thanks to the abstraction of schemas from different heard forms. This abstraction is allowed by analogical reasoning abilities ... [more ▼]

The construction grammar theory claims that language development is achieved thanks to the abstraction of schemas from different heard forms. This abstraction is allowed by analogical reasoning abilities. Analogical reasoning is a human ability, which allows to acquire new knowledge from known situations. Several theories tried to explain its development. Some of them claim that it is an ability that appears late in the development, while others support the hypothesis that it can be used early in the development under certain conditions. Some authors underline the influence of working memory, inhibition or relational knowledge. Relational knowledge about a specific domain will indeed allow to reason analogically and to move from a perceptual reasoning to a relational reasoning. Analogical reasoning and relational knowledge are both connected to language development, as these abilities influence each other. Because of this link, several authors investigated the analogical reasoning abilities of children with language disorders, and specifically of children with Specific Language Impairment (SLI). Those children seem to have poorer analogical reasoning abilities than their age-matched peers. This has implication for the use of analogies in the classroom context, but also for the language development of those children. [less ▲]

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See detailL’infirmier responsable de soins généraux en Belgique, perspective et défis
Dury, Cécile ULg

in Soins Cadres (2016), 98(Vol 25), 55-60

La formation de l’infirmier responsable de soins généraux est en cours de réforme en Belgique pour répondre aux exigences européennes. Il existe un paradoxe de deux niveaux d’enseignement très différents ... [more ▼]

La formation de l’infirmier responsable de soins généraux est en cours de réforme en Belgique pour répondre aux exigences européennes. Il existe un paradoxe de deux niveaux d’enseignement très différents conduisant à un même titre professionnel, dans un cadre institutionnel complexe. La formation relevant de l’enseignement supérieur dans la partie francophone est décrite, et plus spécifiquement son mécanisme de financement, le principe d’autonomie des Hautes Écoles et l’évolution du programme de formation. [less ▲]

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