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See detailReview: Implementing biostimulants and biocontrol strategies in the agroecological management of cultivated ecosystems
Le Mire, Géraldine ULg; Nguyen, Minh ULg; Fassotte, Bérénice ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of ... [more ▼]

This review describes the current methods for exploiting and applying plant growth-promoting rhizbacteria (PGPR), elicitors and semiochemical products in contemporary agricultural systems. The future of these biostimulant and biocontrol tools for the sustainable management of agricultural practices is also discussed. Special attention is given to the formulation of these products and the network of interactions taking place in cultivated ecosystems [less ▲]

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See detailRobust asymptotic tests for the equality of multivariate coefficients of variation
Aerts, Stéphanie ULg; Haesbroeck, Gentiane ULg

in TEST (in press)

In order to easily compare several populations on the basis of more than one feature, multivariate coefficients of variation (MCV) may be used as they allow to summarize relative dispersion in a single ... [more ▼]

In order to easily compare several populations on the basis of more than one feature, multivariate coefficients of variation (MCV) may be used as they allow to summarize relative dispersion in a single index. However, up to date, no test of equality of one or more MCV's has been developed in the literature. In this paper, several classical and robust Wald type tests are proposed and studied. The asymptotic distributions of the test statistics are derived under elliptical symmetry, and the asymptotic efficiency of the robust versions is compared to the classical tests. Robustness of the proposed procedures is examined through partial influence functions of the test statistic, as well as by means of power and level influence functions. A simulation study compares the performance of the classical and robust tests under uncontaminated and contaminated schemes, and the difference with the usual covariance homogeneity test is highlighted. As a by-product, these tests may also be considered in the univariate context where they yield procedures that are both robust and easy-to-use. They provide an interesting alternative to the numerous parametric tests of comparison of univariate coefficients of variation existing in the literature, which are, in most cases, unreliable in presence of outliers. The methods are illustrated on a real data set. [less ▲]

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See detailPhysiological and bio-functional properties of gum arabic: a notable interest for certain human diseases
Eloundou Mballa, Pierre; Goffin, Dorothée ULg; Destain, Jacqueline ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

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See detailDistances between nested densities and a measure of the impact of the prior in Bayesian statistics
Ley, Christophe; Reinert, Gesine; Swan, Yvik ULg

in Annals of Applied Probability (in press)

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See detailIs it possible to improve communication around radiotherapy delivery: A randomized study to assess the efficacy of team training?
Liénard, Aurore; Delevallez, France; Razavi, Darius et al

in Radiotherapy & Oncology (in press)

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See detailResting-state test–retest reliability of a priori defined canonical networks over different preprocessing steps
Varikuti, Deepthi; Hoffstaedter, Felix; Genon, Sarah ULg et al

in Brain Structure & Function (in press)

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI ... [more ▼]

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI, however, is impeded by various nuisance signals that reduce the stability of functional connectivity. Several methods exist to address this predicament, but little consensus has yet been reached on the most appropriate approach. Given the crucial importance of reliability for the development of clinical applications, we here investigated the effect of various confound removal approaches on the test–retest reliability of functional connectivity estimates in two previously defined functional brain networks. Our results showed that gray matter masking improved the reliability of connectivity estimates, whereas denoising based on principal components analysis reduced it. We additionally observed that refraining from using any correction for global signals provided the best test–retest reliability, but failed to reproduce anti-correlations between what have been previously described as antagonistic networks. This suggests that improved reliability can come at the expense of potentially poorer biological validity. Consistent with this, we observed that reliability was proportional to the retained variance, which presumably included structured noise, such as reliable nuisance signals (for instance, noise induced by cardiac processes). We conclude that compromises are necessary between maximizing test–retest reliability and removing variance that may be attributable to non-neuronal sources. [less ▲]

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See detailSummatory function of sequences counting subwords occurrences
Leroy, Julien ULg; Rigo, Michel ULg; Stipulanti, Manon ULg

in Electronic Journal of Combinatorics (in press)

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See detailRobbe-Grillet va plus loin avec l'Express... Le romancier face à l'entretien journalistique
Lorent, Fanny ULg

in Interférences Littéraires = Literaire Interferenties (in press)

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See detailLes associations des enfants et jeunes travailleurs du Burkina Faso comme espace d’expression de la capacité d’action des enfants ?
Wouango, Joséphine ULg

in Enfances Familles Générations (in press)

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années ... [more ▼]

Les Associations des Enfants et Jeunes Travailleurs du Burkina Faso (AEJT/BF) sont une représentation nationale du Mouvement Africain des Enfants et Jeunes Travailleurs (MAEJT), créé à la fin des années 1980. Le mouvement est fondé sur deux grands principes : les douze droits prioritaires des enfants et jeunes travailleurs et le principe du « protagonisme » (l’enfant travailleur comme acteur capable) . Ce chapitre présente et analyse le fonctionnement de ce mouvement au Burkina Faso, les changements qu’il a contribué à apporter à la question sociale du travail des enfants et les résultats de la mise en application des principes annoncés. S’appuyant sur une enquête ethnographique menée en son sein, le texte offre des données inédites sur les réalités d’un acteur collectif qui, en utilisant à son avantage la rhétorique de la « participation » des enfants (art.12, Convention des droits de l’enfant), a réussi à s’insérer dans l’arène nationale de la protection de l’enfance. Toutefois, la question de la place et du rôle des enfants ainsi que celle du “vieillissement” des membres sont quelques-uns des défis auxquels la section burkinabè du mouvement doit faire face. [less ▲]

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See detailBeyond survival and uncertainty. The livelihood practices of former Gécamines workers (D.R.Congo)
Rubbers, Benjamin ULg

in Review of African Political Economy (in press)

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See detailClinical usefulness of bone turnover marker concentrations in osteoporosis.
Morris, H. A.; Eastell, R.; Jorgesen, N. R. et al

in Clinica Chimica Acta (in press)

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the ... [more ▼]

Current evidence continues to support the potential for bone turnover markers (BTM) to provide clinically useful information particularly for monitoring the efficacy of osteoporosis treatment. Many of the limitations identified earlier remain, principally in regard to the relationship between BTM and incident fractures. Important data are now available on reference interval values for CTX and PINP across a range of geographic regions and for individual clinical assays. An apparent lack of comparability between current clinical assays for CTX has become evident indicating the possible limitations of combining such data for meta-analyses. Harmonization of units for reporting serum/plasma CTX (ng/L) and PINP (mug/L) is recommended. The development of international collaborations continues with an important initiative to combine BTM results from clinical trials in osteoporosis in a meta-analysis and an assay harmonization program are likely to be beneficial. It is possible that knowledge derived from clinical studies can further enhance fracture risk estimation tools with inclusion of BTM together with other independent risk factors. Further data of the relationships between the clinical assays for CTX and PINP as well as physiological and pre-analytical factors contributing to variability in BTM concentrations are required. [less ▲]

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See detailInfectivity of a recombinant murine norovirus (RecMNV) in Balb/cByJ mice
Mathijs, Elisabeth; de Oliveira-Filho, Edmilson; Dal Pozzo, Fabiana ULg et al

in Veterinary Microbiology (in press)

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See detailCompte rendu de D. van Mal-Maeder, A. Burnier, L. Núñez (éds.): Jeux de voix. Énonciation, intertextualité et intentionnalité dans la littérature antique
Macedo, Gabriel ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (in press)

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See detailA component method for cold-formed steel beam-to-column bolted gusset plate joints
Bucmys, Zilvinas; Daniunas, Alfonsas; Jaspart, Jean-Pierre ULg et al

in Thin-Walled Structures (in press)

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these ... [more ▼]

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these constructions. This paper presents a study of cold formed steel bolted gusset plate connections. A “three springs” mechanical model to calculate joint stiffness is presented. Then the results predicted through the proposed model are validated through comparisons to experimental and finite element results. [less ▲]

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See detailFrom thoughts to voices: Understanding the development of auditory hallucinations in schizophrenia
Handest, P; Klimpke, C; Raballo, A et al

in Review of Philosophy and Psychology (in press)

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See detailHigh-throughput sequencing analysis reveals the genetic diversity of different regions of the murine norovirus genome during in vitro replication
Mauroy, Axel ULg; Taminiau, Bernard ULg; Nezer, Carine et al

in Archives of Virology (in press)

In this study, we report the genetic diversity and nucleotide mutation rates of five representative regions of the murine norovirus genome during in vitro passages. The mutation rates were similar in ... [more ▼]

In this study, we report the genetic diversity and nucleotide mutation rates of five representative regions of the murine norovirus genome during in vitro passages. The mutation rates were similar in genomic regions encompassing partial coding sequences for non-structural (NS) 1-2, NS5, NS6, NS7 proteins within open reading frame (ORF) 1. In a region encoding a portion of the major capsid protein (VP1) within ORF2 (also including the ORF4 region) and a portion of the minor structural protein (VP2), the mutation rates were estimated to be at least one order of magnitude higher. The VP2 coding region was found to have the highest mutation rate. [less ▲]

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See detailReversible TAD chemistry as a convenient tool for the design of (re)processable PCL-based shape-memory materials
Defize, Thomas ULg; Riva, Raphaël ULg; Thomassin, Jean-Michel ULg et al

in Macromolecular Rapid Communications (in press)

A chemically cross-linked but remarkably (re)processable shape-memory polymer (SMP) is designed by cross-linking poly(ε -caprolactone) (PCL) stars via the efficient triazolinedione click chemistry, based ... [more ▼]

A chemically cross-linked but remarkably (re)processable shape-memory polymer (SMP) is designed by cross-linking poly(ε -caprolactone) (PCL) stars via the efficient triazolinedione click chemistry, based on the very fast and reversible Alder– ene reaction of 1,2,4-triazoline-3,5-dione (TAD) with indole compounds. Typically, a six-arm star-shaped PCL function- alized by indole moieties at the chain ends is melt-blended with a bisfunctional TAD, directly resulting in a cross-linked PCL-based SMP without the need of post-curing treatment. As demonstrated by the stress relaxation measurement, the labile character of the TAD–indole adducts under stress allows for the solid-state plasticity reprocessing of the permanent shape at will by compression molding of the raw cross-linked material, while keeping excellent shape-memory properties. [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailNew insight on Carboniferous (Viséan) brachiopods from eastern Tafilalt (Morocco)
Mottequin, Bernard; Denayer, Julien ULg; Herbig, Hans-Georg et al

in Geological Journal (in press)

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See detailState Created Barriers to Exit - The Example of the Acquisition of Alstom by General Electric
Petit, Nicolas ULg

in Competition Policy International (in press)

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See detailCompte-rendu de l'ouvrage de O. Dubreucq : L'instruction des laïcs de Jonas d'Orléans
Close, Florence ULg

in Revue des Etudes Latines (in press)

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See detailCompte-rendu de l'ouvrage de Boyd Taylor COOLMAN et Dale M. COULTER : Trinity and creation
Close, Florence ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailResurgence of Schmallenberg virus in Belgium after 3 years of epidemiological silence
Delooz, L; Saegerman, Claude ULg; Quinet, C et al

in Transboundary and Emerging Diseases (in press)

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See detailMultiple markers of HVC neurogenesis in the canary
Shevchouk, Olesya ULg; Ball, G.F.; Cornil, Charlotte ULg et al

in PLoS ONE (in press)

In songbirds, neurogenesis in the song control nucleus HVC is sensitive to the hormonal and social environment but the dynamics of this process is difficult to assess with a single exogenous marker of new ... [more ▼]

In songbirds, neurogenesis in the song control nucleus HVC is sensitive to the hormonal and social environment but the dynamics of this process is difficult to assess with a single exogenous marker of new neurons. We simultaneously used three independent markers to investigate HVC neurogenesis in male and female canaries. Males were castrated, implanted with testosterone and housed either alone (M), with a female (M-F) or with another male (M-M) while females were implanted with 17β- estradiol and housed with a male (F-M). All subjects received injections of the two thymidine analogues, BrdU and of EdU, respectively 21 and 10 days before brain collection. Cells containing BrdU or EdU or expressing doublecortin (DCX), which labels newborn neurons, were quantified. Social context and sex differentially affected total BrdU+, EdU+, BrdU+EdU- and DCX+ populations. M-M males had a higher density of BrdU+ cells in the ventricular zone adjacent to HVC and of EdU+ in HVC than M-F males. M birds had a higher ratio of BrdU+EdU- to EdU+ cells than M-F subjects suggesting higher survival of newer neurons in the former group. Total number of HVC DCX+ cells was lower in M-F than in M-M males. Sex differences were also dependent of the type of marker used. Several technical limitations associated with the use of these multiple markers were also identified. These results indicate that proliferation, recruitment and survival of new neurons can be independently affected by environmental conditions and effects can only be fully discerned through the use of multiple neurogenesis markers. [less ▲]

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See detailComprehensive Human Papilloma Virus (HPV) Genotyping in Cervical Squamous Cell Carcinomas and its Relevance to Cervical Cancer Prevention in Malawian Women
Howitt, Brooke; Herfs, Michael ULg; Tomoka, Tamiwe et al

in Journal of Global Oncology (in press)

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See detailAtypical composition and structure of the mitochondrial dimeric ATP synthase from Euglena gracilis
Yadav, K.N. Sathish; Miranda Astudillo, Héctor Vicente ULg; Colina-Tenorio, Lili et al

in Biochimica et Biophysica Acta-Bioenergetics (in press)

Mitochondrial respiratory-chain complexes from Euglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena ... [more ▼]

Mitochondrial respiratory-chain complexes from Euglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena gracilis and Trypanosoma brucei). Here we studied the mitochondrial F1FO-ATP synthase (or Complex V) from the photosynthetic eukaryote E. gracilis in detail. The enzyme was purified by a two-step chromatographic procedure and its subunit composition was resolved by a three-dimensional gel electrophoresis (BN/SDS/SDS). Twenty-two different subunits were identified by mass-spectrometry analyses among which the canonical alpha, beta, gamma, delta, epsilon and OSCP subunits, and at least seven subunits previously found in Trypanosoma. The ADP/ATP carrier was also associated to the ATP synthase into a dimeric ATP synthasome. Single-particle analysis by transmission electron microscopy of the dimeric ATP synthase indicated that the structures of both the catalytic and central rotor parts are conserved while other structural features are original. These new features include a large membrane-spanning region joining the monomers, an external peripheral stalk and a structure that goes through the membrane and reaches the inter membrane space below the c-ring, the latter having not been reported for any mitochondrial F-ATPase. [less ▲]

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See detailUse of primary and secondary polyvinylamines for efficient gene transfection
Dréan, Mathilde; Debuigne, Antoine ULg; Gonçalves, Christine et al

in Biomacromolecules (in press)

Gene transfection with polymeric carrier remains a challenge, particularly high transfection levels combined with low toxicity are hard to achieve. We herein revisit polyvinylamines, an old and neglected ... [more ▼]

Gene transfection with polymeric carrier remains a challenge, particularly high transfection levels combined with low toxicity are hard to achieve. We herein revisit polyvinylamines, an old and neglected family of cationic polymers. They can be readily obtained by controlled hydrolysis of polyvinylamides prepared through (controlled) radical polymerization. A series of tailor-made and well-defined polyvinylamines bearing primary amino groups, and poly(N- methylvinylamine) bearing secondary amines, were evaluated for the transfection of cells with pDNA as a function of their molar mass, molar mass distribution and degree of deacetylation. Unexpected high transfection levels, in combination with low cytotoxicity were recorded for both series. Surprisingly, a great impact of the molar mass was observed for the primary amine polyvinylamine series, whereas the results were mostly independent on molar mass or dispersity for the polymer bearing secondary amine. It was further established that a certain percentage of acetamide groups increased the transfection level, while maintaining low cytotoxicity. These results highlight for the first time the real potential of polyvinylamines as gene carriers, and make these polymers very attractive for further development in gene therapy. [less ▲]

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See detailRelating pessimistic memory predictions to Alzheimer’s disease brain structure
Genon, Sarah ULg; Simon, Jessica ULg; Bahri, Mohamed Ali ULg et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (in press)

Patients with Alzheimer’s disease (AD) show impairment of episodic memory and related metacognitive processes. The present study examined subjective metacognitive judgments preceding objective memory ... [more ▼]

Patients with Alzheimer’s disease (AD) show impairment of episodic memory and related metacognitive processes. The present study examined subjective metacognitive judgments preceding objective memory retrieval and investigated the neural correlates of pessimistic predictions for successfully retrieved memories in AD patients. AD patients and healthy older participants provided predictive judgements on their recognition performance before retrieval of famous (semantic) and recently learned (episodic) names. Correlations between grey matter volume (GMV) in T1 images and behavioural scores were examined with multivariate (PLS) and univariate (GLM) analyses in AD patients. AD patients showed a significant proportion of successful name recognition preceded by pessimistic prediction (Prediction_low_hits) in episodic memory. PLS revealed that behavioural pattern in AD patients was related with a mainly right lateralized pattern of GMV decrease including medial temporal lobe and posterior cingulate cortex, but also right ventrolateral prefrontal cortex (VLPFC). GLM further confirmed that pessimistic prediction negatively correlated with GMV in VLPFC. Thus, impaired monitoring processes (possibly influenced by inaccurate beliefs) allowing inferences about one’s own memory performance are primarily related to decrease GMV in VLPFC in AD patients. [less ▲]

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See detailIncreasing the salience of fluency cues does not reduce the recognition memory impairment in Alzheimer’s disease!
Simon, Jessica ULg; Bastin, Christine ULg; SALMON, Eric ULg et al

in Journal of Neuropsychology (in press)

In Alzheimer’s disease (AD), it is now well established that recollection is impaired from the beginning of the disease, whereas findings are less clear concerning familiarity. One of the most important ... [more ▼]

In Alzheimer’s disease (AD), it is now well established that recollection is impaired from the beginning of the disease, whereas findings are less clear concerning familiarity. One of the most important mechanisms underlying familiarity is the sense of familiarity driven by processing fluency. In this study, we attempted to attenuate recognition memory deficits in AD by maximizing the salience of fluency cues in two conditions of a recognition memory task. In one condition, targets and foils have been created from the same pool of letters (Overlap condition). In a second condition, targets and foils have been derived from two separate pools of letters (No-Overlap condition), promoting the use of letter-driven visual and phonetic fluency. Targets and foils were low-frequency words. The memory tasks were performed by 15 patients with AD and 16 healthy controls. Both groups improved their memory performance in the No-Overlap condition compared to the Overlap condition. Patients with AD were able to use fluency cues during recognition memory as older adults did, but this did not allow to compensate for dysfunction of recognition memory processes. [less ▲]

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See detailGoat breeding in the rural district of Chemini (Algeria)
Moula, Nassim ULg; Ait Kaki, Asma; Touazi, Leghel et al

in Nature & Technology (in press)

The Kabyle goat breed represents 10.52% of the total Algerian market (3.8 million heads). A survey of 69 farmers has been carried out in order to characterize it and its breeding in the District of ... [more ▼]

The Kabyle goat breed represents 10.52% of the total Algerian market (3.8 million heads). A survey of 69 farmers has been carried out in order to characterize it and its breeding in the District of Chemini. The questions focused on household agricultural activities, including breeding of goats, cattle, sheep, rabbits, chicken, turkeys, honeybees and the production of olive oil and figs. The goat morpho-biometric characterization was based on 18 corporal measurements. The Hierarchical Cluster Analysis (HCA) of the farm structures defined four groups of farms, variance between groups accounting for 55.7% of total variability. The average number of goats in groups 1 to 4 was 7.2±2.8, 11.1±3.5, 22.3±1.4 and 3.4±1.0, respectively. Group 3 (n=6), showed the greatest number; it consists of older farmers (67 years old or over) not practicing arboriculture. They also have the largest numbers of sheep (48.67), rabbits (50.83), chicken (48.33) and turkeys (42). Group 4 (n=9), with the lowest number of goats, was the group of young farmers (39 years old or less), more dedicated to cattle breeding (~52 heads) and the production of olive oil (~207 trees) and figs (~47 trees). The 18 morpho-biometric variables were significantly higher in males than in females (p<0.05). The Kabyle goat is small (Height at withers: male: 68.23±0.97cm and female: 65.41±0.55cm) with long hair (male: 12.24±0.51cm, and female: 9.51±0.29cm). Its ears are drooping, its convex profile has a slightly pronounced nasal split and its dress color ranges from dark brown to black. This adapted genetic resource should be key in the development of a local production, based on a strong commitment of farmers inside a breed association, for the production of specimens corresponding to a standard, to be determined collectively. [less ▲]

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See detailp16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: A case series, literature review and commentary
Huang, Eric; Tomic, Mary; Hanamornroongruang, Suchanan et al

in Modern Pathology : An Official Journal of the United States & Canadian Academy of Pathology, Inc (in press)

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See detailModeling structures in fire with SAFIR®: Theoretical background and capabilities
Franssen, Jean-Marc ULg; Gernay, Thomas ULg

in Journal of Structural Fire Engineering (in press)

Purpose: This paper describes the theoretical background and main hypotheses at the basis of SAFIR®, a nonlinear finite element software for modeling structures in fire. The paper also explains how to use ... [more ▼]

Purpose: This paper describes the theoretical background and main hypotheses at the basis of SAFIR®, a nonlinear finite element software for modeling structures in fire. The paper also explains how to use the software at its full extent. The discussed numerical modeling principles can be applied with other similar software. Approach: Following a general overview of the organization of the software, the thermal analysis part is explained, with the basic equations and the different possibilities to apply thermal boundary conditions (compartment fire, localized fire, etc.). Next, the mechanical analysis part is detailed, including the time integration procedures and the different types of finite elements: beam, truss, shell, spring and solid. Finally, the material laws are described. The software capabilities and limitations are discussed throughout the paper. Findings: By accommodating multiple types of finite elements and materials, by allowing the user to consider virtually any section type and to input the fire attack in multiple forms, the software SAFIR® is a comprehensive tool for investigating the behavior of structures in the fire situation. Meanwhile, being developed exclusively for its well-defined field of application, it remains relatively easy to use. Value: The paper will improve the knowledge of readers (researchers, designers and authorities) about numerical modeling used in structural fire engineering in general and the capabilities of a particular software largely used in the fire engineering community. [less ▲]

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See detailAdvances in diagnosis and management of familial pituitary adenomas
JEDIDI, Haroun ULg; ROSTOMYAN, Lilith; POTORAC, Iulia et al

in International Journal of Endocrine Oncology (in press)

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems ... [more ▼]

Familial pituitary adenomas accounts for approximately 5-8 % of all pituitary adenomas. Besides the adenomas occurring as part of syndromic entities that bring together several endocrine or other systems disorders, 2-3% of the familial pituitary adenomas fit into the familial isolated pituitary adenomas (FIPA) syndrome. 20% of FIPA syndromes have shown mutations in the AIP gene and have distinct clinical characteristics. Recent findings have isolated a new non-AIP FIPA syndrome called X-LAG, resulting from duplication in GPR-101 gene. These new advances in the field of pituitary disease are opening up a new challenging domain to both clinician and researcher. This review will focus on these last findings and their contribution to the diagnosis and the management of familial pituitary adenomas. [less ▲]

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See detailRONALD JENN ET CORINE OSTER (dir.) (2014) : Territoires de la traduction. Artois : Artois Presses Université, 212 p.
Oumarou Mal Mazou, Rachid ULg

in Meta : Journal des Traducteurs = Meta : Translators' Journal (in press)

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See detailDe la quantité de demandeurs d’emploi à la qualité de l’accompagnement. Des professionnels entre « esprit gestionnaire » et relation de service
Remy, Céline ULg; Lavitry, Lynda

in Revue Française de Socio-Economie (in press)

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours ... [more ▼]

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours des agents et prestataires des services publics de l’emploi en France et en Belgique francophone. L’objectif est de démontrer que le pilotage du travail des intermédiaires de l’emploi par les indicateurs de mesure donne lieu à des pratiques, parfois clandestines, de mise en conformité avec le rendement statistique de leur activité. Mais parallèlement, les excès d’une quantification perçue comme abusive ou dangereuse pour leur ethos professionnel poussent une partie d’entre eux à agir en contradiction avec ces principes gestionnaires et ce, au nom de l’intérêt du demandeur d’emploi et de la prise en compte de la qualité des emplois, tendances que l’on décèle dans les deux pays étudiés. [less ▲]

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See detailThe neural bases of proactive and reactive control processes in normal aging
Manard, Marine ULg; François, Sarah ULg; Phillips, Christophe ULg et al

in Behavioural Brain Research (in press)

Introduction. Research on cognitive control suggests an age-related decline in proactive control abilities (anticipatory control), whereas reactive control (following conflict detection) seems to remain ... [more ▼]

Introduction. Research on cognitive control suggests an age-related decline in proactive control abilities (anticipatory control), whereas reactive control (following conflict detection) seems to remain intact. As proactive and reactive control abilities are associated with specific brain networks, this study investigated age-related effects on the neural substrates associated with each kind of control. Methods. In an event-related fMRI study, a modified version of the Stroop task was administered to groups of 20 young and 20 older healthy adults. Based on the theory of dual mechanisms of control, the Stroop task has been built to induce proactive or reactive control depending on task context. Results. Behavioral results (p < .05) indicated faster processing of interfering items in the mostly incongruent (MI) than the mostly congruent (MC) context in both young and older participants. fMRI results showed that reactive control is associated with increased activity in left frontal areas for older participants. For proactive control, decreased activity in the bilateral anterior cingulate cortex was associated with more activity in the right middle frontal gyrus in the older than the younger group. Conclusion. These observations support the hypothesis that aging affects the neural networks associated with reactive and proactive cognitive control differentially. These age-related changes are very similar to those observed in young adults with low dopamine availability, suggesting that a general mechanism (prefrontal dopamine availability) may modulate brain networks associated with various kinds of cognitive control. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailThe Sense of Taste in Eighteenth-Century France. Flavours of Silence and Words of Perception
Von Hoffmann, Viktoria ULg

in De achttiende eeuw : Documentatieblad van de Werkgroep Achttiende Eeuw (in press), 48(1-2), 13-27

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See detailPreterm Infant Growth Velocity Calculations: A Systematic Review
Fenton, Tanis; Chan, Hilton; Madhu, Aiswarya et al

in Pediatrics (in press)

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See detailFrom Ontology to Psychoanalysis. Benussi and Musatti on the Concept of Mental Reality
Boccaccini, Federico ULg

in Meinong Studies / Meinong Studien (2018), 9

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See detailCompte-rendu de l'ouvrage de Gilbert Gagné : The Trade and Culture Debate Evidence from US Trade Agreements
Vlassis, Antonios ULg

in Revue Québecoise de Droit International (2017)

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See detailMagnetic Shielding Above 1 T at 20 K With Bulk, Large Grain YBCO Tubes Made by Buffer-aided Top Seeded Melt Growth
Wera, Laurent ULg; Fagnard, Jean-François ULg; Kumar, Numbury Devendra et al

in IEEE Transactions on Applied Superconductivity (2017), 27(4),

YBCO tubes of ~ 10 mm diameter closed at one extremity were engineered by a Buffer-Aided Top Seeded Melt Growth fabrication process (BA-TSMG). These tubes can act as efficient “dc” magnetic shields and ... [more ▼]

YBCO tubes of ~ 10 mm diameter closed at one extremity were engineered by a Buffer-Aided Top Seeded Melt Growth fabrication process (BA-TSMG). These tubes can act as efficient “dc” magnetic shields and are observed to reduce axial flux densities of 1.5 T by a factor of 100 at 20 K. Such performances are comparable in magnitude to the record threshold inductions reported for bulk MgB2 and Bi-2212 materials at lower temperatures. Magnetic shielding measurements for open and closed tubes at 77 K also show that the presence of the cap improves substantially the shielding performance at the closed extremity since it reduces the penetration through the open end. This fabrication technique is extremely promising for shielding “dc” stray fields generated by HTS magnets operated in a temperature range obtained by cryocoolers, liquid hydrogen (20 K) or liquid neon (27 K). [less ▲]

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See detailIdentification of non-stationary dynamical systems using multivariate ARMA models
Bertha, Mathieu ULg; Golinval, Jean-Claude ULg

in Mechanical Systems and Signal Processing (2017), 88

This paper is concerned by the modal identification of time-varying mechanical systems. Based on previous works about autoregressive moving average models in vector form (ARMAV) for the modal ... [more ▼]

This paper is concerned by the modal identification of time-varying mechanical systems. Based on previous works about autoregressive moving average models in vector form (ARMAV) for the modal identification of linear time invariant systems, and time-varying autoregressive moving average models (TV-ARMA) for the identification of nonstationary systems, a time-varying ARMAV (TV-ARMAV) model is presented for the multivariate identification of time-varying systems. It results in the identification of not only the time-varying poles of the system but also of its respective time-varying mode shapes. The method is applied on a time-varying structure composed of a beam on which a mass is moving. [less ▲]

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See detailFinite element model reduction for space thermal analysis
Jacques, Lionel ULg; Béchet, Eric ULg; Kerschen, Gaëtan ULg

in Finite Elements in Analysis and Design (2017), 127

To alleviate the computational burden of the nite element method for thermal analyses involving conduction and radiation, this paper proposes an automatic conductive-radiative reduction process based on ... [more ▼]

To alleviate the computational burden of the nite element method for thermal analyses involving conduction and radiation, this paper proposes an automatic conductive-radiative reduction process based on the clustering of a detailed mesh coming from a structural model for instance. The proposed method leads to a signi cant reduction of the number of radiative exchange factors (REFs) to compute and size of the corresponding matrix. It further keeps accurate conduction information by introducing the concept of physically meaningful super nodes. The REFs between the super nodes are computed through Monte Carlo ray-tracing on the partitioned mesh, preserving the versatility of the method. The resulting conductive-radiative reduced model is solved using standard iterative techniques and the detailed mesh temperatures can be recovered from the super nodes temperatures for further thermo-mechanical analysis. The proposed method is applied to a structural component of the Meteosat Third Generation mission and is benchmarked against ESATAN-TMS, the standard thermal analysis software used in the European aerospace industry. [less ▲]

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See detailImpact of tillage on greenhouse gas emissions by an agricultural crop and dynamics of N2O fluxes: Insights from automated closed chamber measurements
Lognoul, Margaux ULg; Theodorakopoulos, Nicolas ULg; Hiel, Marie-Pierre ULg et al

in Soil & Tillage Research (2017), 167

Our experiment aimed at studying the impact of long term tillage treatments – reduced tillage (RT) and conventional tillage (CT), on CO2 and N2O emissions by soil and at describing the dynamics of N2O ... [more ▼]

Our experiment aimed at studying the impact of long term tillage treatments – reduced tillage (RT) and conventional tillage (CT), on CO2 and N2O emissions by soil and at describing the dynamics of N2O fluxes. Gas measurements were performed from June to October 2015 in a Belgian maize crop, with homemade automated closed chambers, allowing continuous measurement at a high temporal resolution. After 7 years of treatment, CO2 and N2O average emissions were significantly larger in the RT parcel than in the CT parcel. This observation was attributed to the effect of tillage on the distribution of crop residues within the soil profile, leading to higher soil organic C and total N contents and a greater microbial biomass in the upper layer in RT. A single N2O emission peak triggered by a sudden increase of water- filled pore space (WFPS) was observed in the beginning of the measuring campaign. The absence of large emission afterwards was most likely due to a decreasing availability of N as crop grew. N2O background fluxes showed to be significantly correlated to CO2 fluxes but not to WFPS, while the influence of soil temperature remained unclear. Our results question the suitability of reduced tillage as a “climate-smart” practice and suggest that more experiments be conducted on conservation practices and their potent negative effect on environment. [less ▲]

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See detailInternational norms and regions: Mercosur and ASEAN at the time of cultural diversity
Vlassis, Antonios ULg

in Política & Sociedade (2017)

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See detailBaelo dans l'Antiquité tardive. L'occupation du secteur sud-est du forum entre les IIIe et VIe s.
Brassous, Laurent; Deru, Xavier ULg; Rodriguez, Oliva et al

in Melanges de la Casa de Velazquez (2017), 47(1),

Les recherches archéologiques conduites au sud-est du forum de la ville romaine de Baelo claudia ont permis de mettre au jour au-dessus du secteur monumental, plusieurs phases de transformation, d’abandon ... [more ▼]

Les recherches archéologiques conduites au sud-est du forum de la ville romaine de Baelo claudia ont permis de mettre au jour au-dessus du secteur monumental, plusieurs phases de transformation, d’abandon et de réoccupation entre les IIIe et VIe s. Les structures découvertes ainsi que le nombreux mobilier qui leur était associé (monnaies, céramique, verre, métal, faune, etc.) fournissent un éclairage nouveau sur l’histoire et la nature de l’agglomération dans l’antiquité tardive, qui entre la fin du IVe s. et son abandon définitif au VIe s. ressemble moins à une ville qu’à un gros village. [less ▲]

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See detailBioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule
Thiry, Justine ULg; Kok, Miranda ULg; Collard, Laurence ULg et al

in European Journal of Pharmaceutical Sciences (2017), 99

Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft copolymer abbreviated SOL) were produced using hot melt ... [more ▼]

Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft copolymer abbreviated SOL) were produced using hot melt extrusion. Since ITZ possesses a water solubility of less than 1 ng/mL, the aim of this work was to enhance the aqueous solubility of ITZ, and thereby improve its bioavailability. The three formulations consisted of a simple SOL/ITZ amorphous solid dispersion (ASD), an optimized SOL/ITZ/AcDiSol® (super-disintegrant) ASD and an equimolar inclusion complex of ITZ in hydroxypropyl-β-cyclodextrin (substitution degree = 0.63, CD) with SOL. The three formulations were compared in vitro and in vivo to the marketed product Sporanox®. The in vitro enhancement of dissolution rate was evaluated using a biphasic dissolution test. In vitro dissolution results showed that all three formulations had a higher percentage of ITZ released than Sporanox® with the following ranking: SOL/ITZ/CD > SOL/ITZ/AcDiSol® > SOL/ITZ > Sporanox®. The bioavailability of these four formulations was evaluated in rats. The bioanalytical method was optimized so that only 10 μL of blood was withdrawn from the rats using specific volumetric absorptive microsampling devices. This enabled to keep the same rats during the whole study, which was in accordance with the Three Rs rules (reduction, refinement and replacement). Furthermore, this technique allowed the suppression of inter-individual variability. Higher Cmax and AUC were obtained after the administration of all three formulations compared to the levels after the use of Sporanox® as follows: SOL/ITZ/AcDiSol® > SOL/ITZ/CD > SOL/ITZ > Sporanox®. The inversion in the ranking between SOL/ITZ/CD and SOL/ITZ/AcDiSol® made impossible the establishment of an in vitro–vivo correlation. Indeed, very different release rates were obtained in vitro and in vivo for the two optimized formulations. These results suggest that ITZ would be protected inside the core of the SOL micelles even during the absorption step at the intestine, while some agents present in the intestinal fluids could displace ITZ from the hydrophobic cavity of CD by competition. [less ▲]

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See detailStructure impact of two galactomannan fractions on their viscosity properties in dilute solution, unperturbed state and gel state
Gillet, Sébastien; Aguedo, Mario ULg; Petrut, Raoul et al

in International Journal of Biological Macromolecules (2017), 96

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See detailUltrasonic spray pyrolysis as a processing route for templated electrochromic tungsten oxide films
Chatzikyriakou, Dafni ULg; Maho, Anthony ULg; Cloots, Rudi ULg et al

in Microporous and Mesoporous Materials (2017), 240

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See detailEffect of different tillage systems on aggregate structure and inner distribution of organic carbon
Gao, Lili ULg; Beckers, Eléonore ULg; Liang, Guopeng et al

in Geoderma (2017), 288

Tillage is a common agricultural practice affecting soil structure and biogeochemistry. Pore network geometries are crucial to oxygen concentration, gas diffusivity, water location and water movement ... [more ▼]

Tillage is a common agricultural practice affecting soil structure and biogeochemistry. Pore network geometries are crucial to oxygen concentration, gas diffusivity, water location and water movement. Soil aggregates, 4–6 mm in diameter and collected from silty loam in Belgium and sandy loam in China, were scanned using a micro-computed tomography scanner. Images with a pixel size of 6.9 μm were then processed with ImageJ software for pore network analysis. The treatments were no tillage (C-NT) and conventional tillage (C-CT) in China, and shallow tillage (G-ST) and conventional tillage (G-CT) in Belgium. The results showed that aggregates in conservational tillage (G-ST and C-NT) had numerous connected pores compared with conventional tillage (G-CT and C-CT). The Euler number (Ev) was significantly lower and visible total porosity and surface area (SA) were significantly higher in conservational tillage (G-ST and C-NT) than in conventional tillage (G-CT and C-CT) in both studied locations. The predominant size of pores was significantly higher in conservational tillage (G-ST and C-NT) than in conventional tillage (G-CT and C-CT) (> 150 μm vs 90–120 μm). Pore location within the aggregates also showed differences, with porosity being evenly distributed in the aggregates under conventional tillage (G-CT and C-CT). Under conservational tillage (G-ST and C-NT), the aggregates were heterogeneous, showing higher porosity at the center of the aggregates. There was a higher soil organic carbon (SOC) content in the external layer than in the internal layer in conservational tillage in Belgium (G-ST). In no tillage in China (C-NT), the SOC in the external and internal layers, however, showed similar results. Overall, conventional tillage (G-CT and C-CT) reduced the proportion of the largest pores within soil aggregates, whereas there was no significant relationship between pore morphologies and SOC content. Further investigation is required to measure the active and slow carbon pool distribution in the different layers and under different tillage practices. [less ▲]

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See detailStrong XUV irradiation of the Earth-sized exoplanets orbiting the ultracool dwarf TRAPPIST-1
Wheatley, Peter J.; Louden, Tom; Bourrier, Vincent et al

in Monthly Notices of the Royal Astronomical Society (2017), 465

We present an XMM-Newton X-ray observation of TRAPPIST-1, which is an ultracool dwarf star recently discovered to host three transiting and temperate Earth-sized planets. We find the star is a relatively ... [more ▼]

We present an XMM-Newton X-ray observation of TRAPPIST-1, which is an ultracool dwarf star recently discovered to host three transiting and temperate Earth-sized planets. We find the star is a relatively strong and variable coronal X-ray source with an X-ray luminosity similar to that of the quiet Sun, despite its much lower bolometric luminosity. We find L_x/L_bol=2-4x10^-4, with the total XUV emission in the range L_xuv/L_bol=6-9x10^-4. Using a simple energy-limited model we show that the relatively close-in Earth-sized planets, which span the classical habitable zone of the star, are subject to sufficient X-ray and EUV irradiation to significantly alter their primary and perhaps secondary atmospheres. Understanding whether this high-energy irradiation makes the planets more or less habitable is a complex question, but our measured fluxes will be an important input to the necessary models of atmospheric evolution. [less ▲]

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See detailA new asteroseismic diagnostic for internal rotation in γ Doradus stars
Ouazzani, Rhita-Maria; Salmon, Sébastien ULg; Antoci, V. et al

in Monthly Notices of the Royal Astronomical Society (2017), 465

With four years of nearly-continuous photometry from Kepler, we are finally in a good position to apply asteroseismology to $\gamma$ Doradus stars. In particular several analyses have demonstrated the ... [more ▼]

With four years of nearly-continuous photometry from Kepler, we are finally in a good position to apply asteroseismology to $\gamma$ Doradus stars. In particular several analyses have demonstrated the possibility to detect non-uniform period spacings, which have been predicted to be directly related to rotation. In the present work, we define a new seismic diagnostic for rotation in $\gamma$ Doradus stars that are too rapidly rotating to present rotational splittings. Based on the non uniformity of their period spacings, we define the observable $\Sigma$ as the slope of the period spacing when plotted as a function of period. We provide a one-to-one relation between this observable $\Sigma$ and the internal rotation, which applies widely in the instability strip of $\gamma$ Doradus stars. We apply the diagnostic to a handful of stars observed by Kepler. Thanks to g-modes in $\gamma$ Doradus stars, we are now able to determine the internal rotation of stars on the lower main sequence, which is still not possible for Sun-like stars. [less ▲]

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See detailLearning from blind tests: Determining the function of experimental grinding stones through use-wear and residue analysis
Hayes, Elspeth H.; Cnuts, Dries ULg; Lepers, Christian et al

in Journal of Archaeological Science: Reports (2017), 11

Abstract Blind tests provide an objective means to evaluate the accuracy of functional interpretations based on the presence of use-wear and residue traces on stone tools. Previous blind tests have ... [more ▼]

Abstract Blind tests provide an objective means to evaluate the accuracy of functional interpretations based on the presence of use-wear and residue traces on stone tools. Previous blind tests have highlighted interpretive errors commonly associated with use-wear and residue analyses leading to significant methodological developments in each of the respective fields. While a number of blind tests have been performed on flaked stone tools, only a single blind test has been published for use-wear on grinding tools. We present the results of a two-part blind test performed on 15 experimental grinding implements that were used in a controlled setting, designed to evaluate the relative importance of residue analysis for determining the worked material (1) when contextual information is available and (2) when contextual information is absent. We argue that use-wear and residue analyses are successful procedures to identify the use of grinding stones, and that residue analysis may be a particularly valuable means for determining the worked material on tools that have insufficient use-wear development. We suggest that residues should be sufficiently abundant to infer use, if we are to avoid the potential confusion caused by contamination. [less ▲]

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See detailQuantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
Dispas, Amandine ULg; Desfontaine, Vincent; Andri, Bertyl ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2017), 134

In the last years, supercritical fluid chromatography has largely been acknowledged as a singular and performing technique in the field of separation sciences. Recent studies highlighted the interest of ... [more ▼]

In the last years, supercritical fluid chromatography has largely been acknowledged as a singular and performing technique in the field of separation sciences. Recent studies highlighted the interest of SFC for the quality control of pharmaceuticals, especially in the case of the determination of the active pharmaceutical ingredient (API).Nevertheless, quality control requires also the determination of impurities. The objectives of the present work were to i) demonstrate the interest of SFC as a reference technique for the determination of impurities in salbutamol sulfate API and ii) to propose an alternative to a reference HPLC method from the European Pharmacopeia (EP) involving ionpairing reagent. Firstly, a screening was carried out to select the most adequate and selective stationary phase. Secondly, in the context of robust optimization strategy, the method was developed using design space methodology. The separation of salbutamol sulfate and related impurities was achieved in 7 minutes, which is seven times faster than the LC-UV method proposed by European Pharmacopeia (total run time of 50 minutes). Finally, full validation using accuracy profile approach was successfully achieved for the determination of impurities B, D, F and G in salbutamol sulfate raw material. The validated dosing range covered 50 to 150 % of the targeted concentration (corresponding to 0.3 % concentration level), LODs close to 0.5 μg/mL were estimated. The SFC method proposed in this study could be presented as a suitable fast alternative to EP LC method for the quantitative determination of salbutamol impurities. [less ▲]

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See detailVoyage[s] à travers le thymus
Geenen, Vincent ULg

in Science et Culture (2017), (465), 14-15

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See detailResidential heat pump as flexible load for direct control service with parametrized duration and rebound effect
Georges, Emeline ULg; Cornélusse, Bertrand ULg; Ernst, Damien ULg et al

in Applied Energy (2017), 187

This paper addresses the problem of an aggregator controlling residential heat pumps to offer a direct control flexibility service. The service consists of a power modulation, upward or downward, that is ... [more ▼]

This paper addresses the problem of an aggregator controlling residential heat pumps to offer a direct control flexibility service. The service consists of a power modulation, upward or downward, that is activated at a given time period over a fixed number of periods. The service modulation is relative to an optimized baseline that minimizes the energy costs. The load modulation is directly followed by a constrained rebound effect, consisting of a delay time with no deviations from the baseline consumption and a payback time to return to the baseline state. The potential amount of modulation and the constrained rebound effect are computed by solving mixed integer linear problems. Within these problems, the thermal behavior of the building is modeled by an equivalent thermal network made of resistances and lumped capacitances. Simulations are performed for different sets of buildings typical of the Belgian residential building stock and are presented in terms of achievable modulation amplitude, deviations from the baseline and associated costs. A cluster of one hundred ideal buildings, corresponding to retrofitted freestanding houses, is then chosen to investigate the influence of each parameter defined within the service. Results show that with a set of one hundred heat pumps, a load aggregator could expect to harvest mean modulation amplitudes of up to 138 kW for an upward modulation and up to 51 kW for a downward modulation. The obtained values strongly depend on the proposed flexibility service. For example, they can decrease down to 2.6 kW and 0.4 kW, respectively, if no rebound effect is allowed. [less ▲]

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See detailClinical settings in knee osteoarthritis: Pathophysiology guides treatment
Herrero-Beaumont, Gabriel; Roman-Blas, Jorge A; Bruyère, Olivier ULg et al

in Maturitas (2017), 96

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and aging with ... [more ▼]

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and aging with mechanical factors and systemic inflammation-associated metabolic syndrome lead to joint damage. Thus, the expression of a clinical phenotype in the early stages of OA relies on the main underlying pathway and predominant joint tissue involved at a given time. Moreover, OA often coexists with other morbidities in the same patient, which in turn condition the OA process. In this scenario, an appropriate identification of clinical phenotypes, especially in the early stages of the disease, may optimize the design of individualized treatments in OA. An ESCEO-EUGMS (European Union Geriatric Medicine Society) working group has recently suggested possible patient profiles in OA. Hereby, we propose the existence of 4 clinical phenotypes – biomechanical, osteoporotic, metabolic and inflammatory – whose characterization would help to properly stratify patients with OA in clinical trials or studies. Further research in this field is warranted. [less ▲]

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See detailChez Froidmont au Nord : lectures polyphoniques d’une quête identitaire
Baiwir, Esther ULg; Adams, Juliette; Demonchaux, Chloé et al

in La tortue verte. Revue en ligne des littératures francophones (2017)

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See detailThe importance of open data and software: Is energy research lagging behind?
Pfenninger, Stefan; DeCariolis, Joseph; Hirth, Lion et al

in Energy Policy (2017)

Energy policy often builds on insights gained from quantitative energy models and their underlying data. As climate change mitigation and economic concerns drive a sustained transformation of the energy ... [more ▼]

Energy policy often builds on insights gained from quantitative energy models and their underlying data. As climate change mitigation and economic concerns drive a sustained transformation of the energy sector, transparent and well-founded analyses are more important than ever. We assert that models and their associated data must be openly available to facilitate higher quality science, greater productivity through less duplicated effort, and a more effective science-policy boundary. There are also valid reasons why data and code are not open: ethical and security concerns, unwanted exposure, additional workload, and institutional or personal inertia. Overall, energy policy research ostensibly lags behind other fields in promoting more open and reproducible science. We take stock of the status quo and propose actionable steps forward for the energy research community to ensure that it can better engage with decision-makers and continues to deliver robust policy advice in a transparent and reproducible way. [less ▲]

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See detailPhotocleavable stabilizer for the preparation of PHEMA nanogels by dispersion polymerization in supercritical carbon dioxide
Alaimo, David; Grignard, Bruno ULg; Kuppan, Chandrasekar et al

in Polymer Chemistry (2017), 8(3), 581-591

A new photo-sensitive diblock copolymer composed of a hydrophilic sequence of poly(ethylene oxide) (PEO) linked to a CO2-philic sequence of poly(1H,1H,2H,2H-heptadecafluorodecyl acrylate) (PFDA) by a ... [more ▼]

A new photo-sensitive diblock copolymer composed of a hydrophilic sequence of poly(ethylene oxide) (PEO) linked to a CO2-philic sequence of poly(1H,1H,2H,2H-heptadecafluorodecyl acrylate) (PFDA) by a light sensitive o- nitrobenzyl group was successfully synthesized by RAFT polymerization and used as stabilizer for the free radical polymerization of 2-hydroxyethyl methacrylate (HEMA) in dispersion in ?,?,?-trifluorotoluene and supercritical carbon dioxide (scCO2). Thanks to this fluorinated stabilizer, well-defined particles of PHEMA down to 350 nm of diameter were produced in scCO2. Advantageously, the photocleavable group at the block junction of the stabilizer could be cleaved by exposing the particles to UV light so that the fluorinated block could be extracted in TFT or scCO2. As supported by X-ray photoelectron spectroscopy (XPS) analysis, up to 80 % of the fluorinated block of the stabilizer can be removed, leading to efficient swelling and dispersion of the resulting PHEMA nanogels in water. [less ▲]

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See detailPresent-day central African forest is a legacy of the 19th century human history
Morin, Julie ULg; Fayolle, Adeline ULg; Favier, Charly et al

in eLife (2017)

The populations of light-demanding trees that dominate the canopy of central African forests are now aging. Here, we show that the lack of regeneration of these populations began ca. 165 ya (around 1850 ... [more ▼]

The populations of light-demanding trees that dominate the canopy of central African forests are now aging. Here, we show that the lack of regeneration of these populations began ca. 165 ya (around 1850) after major anthropogenic disturbances ceased. Since 1885, less itinerancy and disturbance in the forest has occurred because the colonial administrations concentrated people and villages along the primary communication axes. Local populations formerly gardened the forest by creating scattered openings, which were sufficiently large for the establishment of light-demanding trees. Currently, common logging operations do not create suitable openings for the regeneration of these species, whereas deforestation degrades landscapes. Using an interdisciplinary approach, which included paleoecological, archaeological, historical, and dendrological data, we highlight the long-term history of human activities across central African forests and assess the contribution of these activities to present-day forest structure and composition. The conclusions of this sobering analysis present challenges to current silvicultural practices and to those of the future. [less ▲]

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See detailCryopreservation of chicken primordial germ cells by vitrification and slow-freezing: a comparative study
Tonus, Céline ULg; Connan, Delphine ULg; Waroux, Olivier ULg et al

in Theriogenology (2017), 88

In the present study, we compare a classical slow freezing method and an aseptic vitrification technique to cryopreserve a stable Primordial Gem Cells (PGCs) line issued from the Ardennaise chicken breed ... [more ▼]

In the present study, we compare a classical slow freezing method and an aseptic vitrification technique to cryopreserve a stable Primordial Gem Cells (PGCs) line issued from the Ardennaise chicken breed. Viability immediately after warming was close to 80% and did not differ between the two cryopreservation methods. Proliferation tended to be slower for both cryopreservation methods compared to controls, but the difference was significant only for vitrification. No difference was found between the two methods after flow cytometry analysis of SSEA-1 expression and RT-PCR on several factors related to PGCs phenotype. After one week in culture, all cryopreserved cells reached controls main morphological and expanding (viability/proliferation) features. However, slow freezing generated more unwanted cells clusters than vitrification. After injection of the PGCs into recipient embryos, vitrified PGCs showed a clear, yet not significant, tendency to colonize the gonad at a higher rate than slow frozen PGCs. Slow freezing in cryovials remains simple, inexpensive and less technically demanding than vitrification. Nevertheless, the intrinsic advantages of our aseptic vitrification method and the present study suggest that this should be considered as safer than classical slow freezing for cryopreserving chicken PGCs. [less ▲]

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See detailMicrobiological load of edible insects found in Belgium
Caparros Megido, Rudy ULg; Desmedt, Sandrine; Blecker, Christophe ULg et al

in Insects (2017)

Edible insects are gaining more and more attention as a sustainable source of animal protein for food and feed in the future. In Belgium, some insect products can be found on the market, and consumers are ... [more ▼]

Edible insects are gaining more and more attention as a sustainable source of animal protein for food and feed in the future. In Belgium, some insect products can be found on the market, and consumers are sourcing fresh insects from fishing stores or towards traditional markets to find exotic insects that are illegal and not sanitarily controlled. From this perspective, this study aims to characterize the microbial load of edible insects found in Belgium (i.e., fresh mealworms and house crickets from European farms and smoked termites and caterpillars from a traditional Congolese market) and to evaluate the efficiency of different processing methods (blanching for all species and freeze-drying and sterilization for European species) in reducing microorganism counts. All untreated insect samples had a total aerobic count higher than the limit for fresh minced meat (6.7 log cfu/g). Nevertheless, a species-dependent blanching step has led to a reduction of the total aerobic count under this limit, except for one caterpillar species. Freeze-drying and sterilization treatments on European species were also effective in reducing the total aerobic count. Yeast and mold counts for untreated insects were above the Good Manufacturing Practice limits for raw meat, but all treatments attained a reduction of these microorganisms under this limit. These results confirmed that fresh insects, but also smoked insects from non-European trades, need a cooking step (at least composed of a first blanching step) before consumption. Therefore, blanching timing for each studied insect species is proposed and discussed. [less ▲]

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See detailFermi-LAT kills dark matter interpretations of AMS-02 data. Or not?
Belotsky, Konstantin; Budaev, Ruslan; Kirillov, Alexander et al

in Journal of Cosmology and Astroparticle Physics (2017)

A number of papers attempt to explain the positron anomaly in cosmic rays, observed by PAMELA and AMS-02, in terms of dark matter (DM) decays or annihilations. However, the recent progress in cosmic gamma ... [more ▼]

A number of papers attempt to explain the positron anomaly in cosmic rays, observed by PAMELA and AMS-02, in terms of dark matter (DM) decays or annihilations. However, the recent progress in cosmic gamma-ray studies challenges these attempts. Indeed, as we show, any rational DM model explaining the positron anomaly abundantly produces final state radiation and Inverse Compton gamma rays, which inevitably leads to a contradiction with Fermi-LAT isotropic diffuse gamma-ray background measurements. Furthermore, the Fermi-LAT observation of Milky Way dwarf satellites, supposed to be rich in DM, revealed no significant signal in gamma rays. We propose a generic approach in which the major contribution to cosmic rays comes from the dark matter disc and prove that the tension between the DM origin of the positron anomaly and the cosmic gamma-ray observations can be relieved. We consider both a simple model, in which DM decay/annihilate into charged leptons, and a model-independent minimal case of particle production, and we estimate the optimal thickness of DM disk. Possible mechanisms of formation and its properties are briefly discussed. [less ▲]

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See detailRe-emergence of the Schmallenberg virus associated triad hydranencephaly-micromyelia-arthrogryposis in a newborn calf in Belgium, 2016
Bayrou, Calixte ULg; Garigliany, Mutien-Marie ULg; Cassart, Dominique ULg et al

in Veterinary Record Case Reports (2017), 4(1), 000342

Schmallenberg virus (SBV) emerged in Germany in 2011, then spread rapidly across Europe, causing an epizootic outbreak of abortion, stillbirth and birth at term of lambs, kids and calves with neurological ... [more ▼]

Schmallenberg virus (SBV) emerged in Germany in 2011, then spread rapidly across Europe, causing an epizootic outbreak of abortion, stillbirth and birth at term of lambs, kids and calves with neurological signs and/or musculo-skeletal malformations. SBV-associated disease in newborns disappeared in Belgium in 2013. Here, we describe a SBV genomic RNA-positive malformed calf born in May 2016. It reveals the return of SBV circulation during the fall 2015 in the said area. [less ▲]

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See detailFirst scattered-light images of the gas-rich debris disk around 49 Ceti
Choquet, É.; Milli, J.; Wahhaj, Z. et al

in Astrophysical Journal Letters (2017), 834(2), 12

We present the first scattered-light images of the debris disk around 49 ceti, a ~40 Myr A1 main sequence star at 59 pc, famous for hosting two massive dust belts as well as large quantities of atomic and ... [more ▼]

We present the first scattered-light images of the debris disk around 49 ceti, a ~40 Myr A1 main sequence star at 59 pc, famous for hosting two massive dust belts as well as large quantities of atomic and molecular gas. The outer disk is revealed in reprocessed archival Hubble Space Telescope NICMOS F110W images, as well as new coronagraphic H band images from the Very Large Telescope SPHERE instrument. The disk extends from 1.1" (65 AU) to 4.6" (250 AU), and is seen at an inclination of 73degr, which refines previous measurements at lower angular resolution. We also report no companion detection larger than 3 M_Jup at projected separations beyond 20 AU from the star (0.34"). Comparison between the F110W and H-band images is consistent with a grey color of 49 ceti's dust, indicating grains larger than >2microns. Our photometric measurements indicate a scattering efficiency / infrared excess ratio of 0.2-0.4, relatively low compared to other characterized debris disks. We find that 49 ceti presents morphological and scattering properties very similar to the gas-rich HD 131835 system. From our constraint on the disk inclination we find that the atomic gas previously detected in absorption must extend to the inner disk, and that the latter must be depleted of CO gas. Building on previous studies, we propose a schematic view of the system describing the dust and gas structure around 49 ceti and hypothetic scenarios for the gas nature and origin. [less ▲]

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See detailPollen nutrients better explain bumblebee colony development than pollen diversity
Moerman, Romain; Vanderplanck, Maryse ULg; Fournier, Denis et al

in Insect Conservation and Diversity (2017)

1. Bumblebees are valuable pollinators of numerous wild and cultivated plants. They can forage on variable pollen resources. As some pollen species lack particular nutrients or have global low nutritional ... [more ▼]

1. Bumblebees are valuable pollinators of numerous wild and cultivated plants. They can forage on variable pollen resources. As some pollen species lack particular nutrients or have global low nutritional quality, it has been suggested that bumblebees mix their pollen incomes to ensure a global balanced diet. The hypothesis that a mixed pollen diet better supports bumblebee colony development than a single pollen diet has been poorly explored. 2. We compared the impact of mono-, di- and trifloral diets on microcolony development of Bombus terrestris using three pollen resources with different nutrient contents (Cytisus scoparius, Erica sp. and Sorbus aucuparia) as well as their mixes. Nine parameters (e.g. pollen efficacy: total weight of larvae/total weight of pollen collection) were used to compare the microcolony performances. Moreover, we measured the influence of the pollen diversity and nutritional composition on relevant parameters. 3. We showed that microcolonies can potentially better develop on mixed pollen diets, but single pollen diet can also be as good as mixed pollen diet. Moreover, the sterol concentration appeared as a key factor to establish the impact of a pollen diet on the bumblebee colony development. 4. This study reveals that diverse pollen diet does not necessary equate with good colony development and supports the importance of selecting floral resources by considering their nutrient contents for bee conservation management. [less ▲]

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See detailSegregation and pattern formation in dilute granular media under microgravity conditions
Opsomer, Eric ULg; Noirhomme, Martial ULg; Vandewalle, Nicolas ULg et al

in NPJ Microgravity (2017), 3

Space exploration and exploitation face a major challenge: the handling of granular materials in low-gravity environments. Indeed, grains behave quite differently in space than on Earth, and the ... [more ▼]

Space exploration and exploitation face a major challenge: the handling of granular materials in low-gravity environments. Indeed, grains behave quite differently in space than on Earth, and the dissipative nature of the collisions between solid particles leads to clustering. Within poly-disperse materials, the question of segregation is highly relevant but has not been addressed so far in microgravity. From parabolic flight experiments on dilute binary granular media, we show that clustering can trigger a segregation mechanism, and we observe, for the first time, the formation of layered structures in the bulk. [less ▲]

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See detailCompte rendu de Lavocat (Françoise), Fait et fiction, Paris, Seuil, "Poétique", 2016, 618p.
Huppe, Justine ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2017)

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See detailHow should proxies of Cognitive Reserve be evaluated in a population of healthy older adults?
Grotz, Catherine ULg; Seron, Xavier; Van Wissen, Marie et al

in International Psychogeriatrics (2017), 29(1), 123-136

Background: While some tools have been developed to estimate an individual’s cognitive reserve (CR), no study has assessed the adequacy of the method used for assessing these CR proxy indicators ... [more ▼]

Background: While some tools have been developed to estimate an individual’s cognitive reserve (CR), no study has assessed the adequacy of the method used for assessing these CR proxy indicators. Therefore, we aimed to determine the most appropriate method to estimate CR by comparing two approaches: 1) the common assessment of CR proxies in the literature (e.g., years of education) and 2) the calculation of a comprehensive index based on most significant parameters used in the estimation of CR. Methods: Data on CR proxies: (i.e., education, occupation and leisure activities) were obtained in a sample of 204 older adults. Regression analyses were used to develop the two indices of CR (i.e., ICR-standard and ICR-detailed) and to determine which index best represented the level of one’s CR. Results: The ICR-standard was calculated using a combination of the three most common measures of reserve in the literature: number of schooling years, complexity of the primary occupation and amount of current participation in stimulating activities. The ICR-detailed was calculated using the most significant parameters (established in initial analyses) of CR: highest level of education combined with the number of training courses, last occupation and amount of current participation in social and intellectual activities. The comparison of both indices showed that higher levels of ICR-standard and ICR-detailed were associated with a greater minimization of the effects of age on cognition. However, the ICR-detailed was more strongly associated to this minimization than the ICR-standard, suggesting that the ICR-detailed best reflect one’s CR. Conclusion: This study is the first to show that it is of great importance to question methods measuring CR proxies in order to develop a clinical tool allowing a comprehensive and accurate estimation of CR. [less ▲]

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See detailHot-Melt Extrusion as a Continuous Manufacturing Process to Form Ternary Cyclodextrin Inclusion Complexes
Thiry, Justine ULg; Krier, Fabrice; Ratwatte, Shenelka et al

in European Journal of Pharmaceutical Sciences (2017), 96

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See detailRossiter-McLaughlin models and their effect on estimates of stellar rotation, illustrated using six WASP systems
Brown, D. J. A.; Triaud, A. H. M. J.; Doyle, A. P. et al

in Monthly Notices of the Royal Astronomical Society (2017), 464

We present new measurements of the projected spin--orbit angle $\lambda$ for six WASP hot Jupiters, four of which are new to the literature (WASP-61, -62, -76, and -78), and two of which are new analyses ... [more ▼]

We present new measurements of the projected spin--orbit angle $\lambda$ for six WASP hot Jupiters, four of which are new to the literature (WASP-61, -62, -76, and -78), and two of which are new analyses of previously measured systems using new data (WASP-71, and -79). We use three different models based on two different techniques: radial velocity measurements of the Rossiter--McLaughlin effect, and Doppler tomography. Our comparison of the different models reveals that they produce projected stellar rotation velocities ($v \sin I_{\rm s}$) measurements often in disagreement with each other and with estimates obtained from spectral line broadening. The Bou\'e model for the Rossiter--McLaughlin effect consistently underestimates the value of $v\sin I_{\rm s}$ compared to the Hirano model. Although $v \sin I_s$ differed, the effect on $\lambda$ was small for our sample, with all three methods producing values in agreement with each other. Using Doppler tomography, we find that WASP-61\,b ($\lambda=4^\circ.0^{+17.1}_{-18.4}$), WASP-71\,b ($\lambda=-1^\circ.9^{+7.1}_{-7.5}$), and WASP-78\,b ($\lambda=-6^\circ.4\pm5.9$) are aligned. WASP-62\,b ($\lambda=19^\circ.4^{+5.1}_{-4.9}$) is found to be slightly misaligned, while WASP-79\,b ($\lambda=-95^\circ.2^{+0.9}_{-1.0}$) is confirmed to be strongly misaligned and has a retrograde orbit. We explore a range of possibilities for the orbit of WASP-76\,b, finding that the orbit is likely to be strongly misaligned in the positive $\lambda$ direction. [less ▲]

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See detailWater loss from terrestrial planets orbiting ultracool dwarfs: implications for the planets of TRAPPIST-1
Bolmont, E.; Selsis, F.; Owen, J. E. et al

in Monthly Notices of the Royal Astronomical Society (2017), 464

Ultracool dwarfs (UCD; $T_{\rm eff}<\sim3000~$K) cool to settle on the main sequence after $\sim$1 Gyr. For brown dwarfs, this cooling never stops. Their habitable zone (HZ) thus sweeps inward at least ... [more ▼]

Ultracool dwarfs (UCD; $T_{\rm eff}<\sim3000~$K) cool to settle on the main sequence after $\sim$1 Gyr. For brown dwarfs, this cooling never stops. Their habitable zone (HZ) thus sweeps inward at least during the first Gyr of their lives. Assuming they possess water, planets found in the HZ of UCDs have experienced a runaway greenhouse phase too hot for liquid water prior to entering the HZ. It has been proposed that such planets are desiccated by this hot early phase and enter the HZ as dry worlds. Here we model the water loss during this pre-HZ hot phase taking into account recent upper limits on the XUV emission of UCDs and using 1D radiation-hydrodynamic simulations. We address the whole range of UCDs but also focus on the planets recently found around the $0.08~M_\odot$ dwarf TRAPPIST-1. Despite assumptions maximizing the FUV-photolysis of water and the XUV-driven escape of hydrogen, we find that planets can retain significant amounts of water in the HZ of UCDs, with a sweet spot in the $0.04$-$0.06~M_\odot$ range. We also studied the TRAPPIST-1 system using observed constraints on the XUV-flux. We find that TRAPPIST-1b and c may have lost as much as 15 Earth Oceans and planet d -- which might be inside the HZ -- may have lost less than 1 Earth Ocean. Depending on their initial water contents, they could have enough water to remain habitable. TRAPPIST-1 planets are key targets for atmospheric characterization and could provide strong constraints on the water erosion around UCDs. [less ▲]

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See detailFirst limits on the occurrence rate of short-period planets orbiting brown dwarfs
He, Matthias Y.; Triaud, Amaury H. M. J.; Gillon, Michaël ULg

in Monthly Notices of the Royal Astronomical Society (2017), 464

Planet formation theories predict a large but still undetected population of short-period terrestrial planets orbiting brown dwarfs. Should specimens of this population be discovered transiting relatively ... [more ▼]

Planet formation theories predict a large but still undetected population of short-period terrestrial planets orbiting brown dwarfs. Should specimens of this population be discovered transiting relatively bright and nearby brown dwarfs, the Jupiter-size and the low luminosity of their hosts would make them exquisite targets for detailed atmospheric characterisation with JWST and future ground-based facilities. The eventual discovery and detailed study of a significant sample of transiting terrestrial planets orbiting nearby brown dwarfs could prove to be useful not only for comparative exoplanetology but also for astrobiology, by bringing us key information on the physical requirements and timescale for the emergence of life. In this context, we present a search for transit-signals in archival time-series photometry acquired by the Spitzer Space Telescope for a sample of 44 nearby brown dwarfs. While these 44 targets were not particularly selected for their brightness, the high precision of their Spitzer light curves allows us to reach sensitivities below Earth-sized planets for 75% of the sample and down to Europa-sized planets on the brighter targets. We could not identify any unambiguous planetary signal. Instead, we could compute the first limits on the presence of planets on close-in orbits. We find that within a 1.28 day orbit, the occurrence rate of planets with a radius between 0.75 and 3.25 R$_\oplus$ is {\eta} < 67 $\pm$ 1%. For planets with radii between 0.75 and 1.25 R$_\oplus$, we place a 95% confident upper limit of {\eta} < 87 $\pm$ 3%. If we assume an occurrence rate of {\eta} = 27% for these planets with radii between 0.75 and 1.25 R$_\oplus$, as the discoveries of the Kepler-42b and TRAPPIST-1b systems would suggest, we estimate that 175 brown dwarfs need to be monitored in order to guarantee (95%) at least one detection. [less ▲]

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See detailH.M. Enzensberger contre l'amertume du vieillard. Des "groupes vidéos" à Youtube (et retour).
Hamers, Jérémy ULg

in Cahier Louis-Lumière (2017), 10

By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link ... [more ▼]

By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link between various past and contemporary media devices. The identification of this link makes it possible to free theoretical critique of the evolutionary paradigm of failure and progress (technological and political), opening it up to a set of reciprocal and non-linear insights. In this context, the use of Enzensberger texts also goes beyond any form of periodisation. By engaging a dialogue with his “Jeu de construction pour une théorie des medias” / Constituents of a Theory of the Media (1970), several essays gathered in Médiocrité et folie / Mediocrity and Madness (1988), as well as his recent autobiographical interview Erinnerungen an einen Tumult (2014), this text shows how criticism by the German writer, while constantly revitalised by the emergence of “new” objects (tabloid press, mobile video, television, Internet, smartphones), invites us to overcome any technological determinism to simultaneously consider the political potential of the first activist video groups and platforms dominating the Internet today. [less ▲]

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See detailMorphology of the filtration apparatus of three planktivorous fishes and relation with ingested anthropogenic particles
Collard, France ULg; Gilbert, Bernard ULg; Eppe, Gauthier ULg et al

in Marine Pollution Bulletin (2017)

Anthropogenic particles (APs), including microplastics, are ingested by a wide variety of marine organisms. Exposure of Clupeiformes (e.g. herrings, anchovies, sardines) is poorly studied despite their ... [more ▼]

Anthropogenic particles (APs), including microplastics, are ingested by a wide variety of marine organisms. Exposure of Clupeiformes (e.g. herrings, anchovies, sardines) is poorly studied despite their economic and ecological importance. This study aims to describe the morphology of the filtration apparatus of three wild-caught Clupeiformes (Sardina pilchardus, Clupea harengus and Engraulis encrasicolus) and to relate the results to ingested APs. Consequently, the species with the more efficient filtration apparatus will be more likely to ingest APs. We hypothesized that sardines were the most exposed species. The filtration area and particle retention threshold were determined in the three species, with sardines displaying the highest filtration area and the closest gill rakers. Sardines ingested more fibers and smaller fragments, confirming that it is the most efficient filtering species. These two results lead to the conclusion that, among the three studied, the sardine is the species most exposed to APs. [less ▲]

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See detailEnonciation et modes d'existence
Dondero, Maria Giulia ULg

in Nouveaux Actes Sémiotiques (2017)

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique ... [more ▼]

Cet article aborde les relations entre sémiotique et philosophie latourienne à partir de la théorie de l’énonciation, cette dernière se situant tant aux fondements du projet disciplinaire de la sémiotique francophone contemporaine qu’à la base de la réflexion de Bruno Latour, des années 1970 jusqu’à présent . Notre propos se déploie en deux moments : dans un premier temps, nous revenons sur l’article "Petite Philosophie de l’énonciation" (1998), et nous en suivons le développement dans l’Enquête sur les modes d’existence (2012). Dans un second temps, nous réalisons une rapide archéologie de la théorie de l’énonciation dans la sémiotique contemporaine, afin de mettre en lumière les liens entre différentes traditions sémiotiques et la théorie latourienne. Plus précisément, nous nous attachons aux propositions récentes de Jacques Fontanille et de Claudio Paolucci, en prenant également en considération les contributions d’Umberto Eco et Patrizia Violi. Il s’agit de voir comment les sémioticiens peuvent tirer profit de la théorie latourienne des modes d’existence et vice versa. [less ▲]

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See detailEuropean consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: Diagnosis
WERNER R. N.; NIKKELS, Arjen ULg; MARINOVIC B. et al

in Journal of the European Academy of Dermatology & Venereology (2017), 31

Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim ... [more ▼]

Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localizations. This interdisciplinary guideline aims at an improvement of the outcomes of the acute HZ management concerning disease duration, acute pain and quality of life of the affected patients and at a reduction of the incidence of postherpetic neuralgia and other complications. The guideline development followed a structured and predefined process, considering the quality criteria for guidelines development as suggested by the AGREE II instrument. The steering group was responsible for the planning and the organization of the guideline development process (Division of Evidence based Medicine, dEBM). The expert panel was nominated by virtue of clinical expertise and/or scientific experience and included experts from the fields of dermatology, virology/infectiology, ophthalmology, otolaryngology, neurology and anaesthesiology. Recommendations for clinical practice were formally consented during the consensus conference, explicitly considering different relevant aspects. The guideline was approved by the commissioning societies after an extensive internal and external review process. In this first part of the guideline, diagnostic means have been evaluated. The expert panel formally consented recommendations for the management of patients with (suspected) HZ, referring to the assessment of HZ patients, considering various specific clinical situations. Users of the guideline must carefully check whether the recommendations are appropriate for the context of intended application. In the setting of an international guideline, it is generally important to consider different national approaches and legal circumstances with regard to the regulatory approval, availability and reimbursement of diagnostic and therapeutic interventions. [less ▲]

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See detailBioclimatism in Architecture : an evolutionary perspective
Nguyen, Anh Tuan; Reiter, Sigrid ULg

in International Journal of Design and Nature and Ecodynamics (2017), 12(1), 16-29

Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that ... [more ▼]

Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that the development of bioclimatism in architecture has followed the pattern of a natural evolutionary process in which “natural selection” is likely motivated by several factors, including resources and environment problems, and driven by different mechanisms including novel building design concepts and methods, new standards and codes, discoveries in building science and construction costs. This study is an effort aimed to clarify the evolution process of the bioclimatic approach in architecture over time and its influences on contemporary movements in architecture. The paper shows also that the evolutionary theory generated new scientific tools able to improve building design thanks to simulation-based optimization methods applied to building performances. Finally, this study investigates new motivations in the era of climate change whose effects are expected to introduce more challenges as well as more trends towards a sustainable built environment through the new concept of Eco-adaptive architecture. [less ▲]

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See detailSpatial variation in the accumulation of POPs and mercury in bottlenose dolphins of the Lower Florida Keys and the coastal Everglades (South Florida)
Damseaux, France ULg; Kiszka, J.; Heithaus, M.R. et al

in Environmental Pollution (2017), 220

The bottlenose dolphin (Tursiops truncatus) is an upper trophic level predator and the most common cetacean species found in nearshore waters of southern Florida, including the Lower Florida Keys (LFK ... [more ▼]

The bottlenose dolphin (Tursiops truncatus) is an upper trophic level predator and the most common cetacean species found in nearshore waters of southern Florida, including the Lower Florida Keys (LFK) and the Florida Coastal Everglades (FCE). The objective of this study was to assess contamination levels of total mercury (T-Hg) in skin and persistent organic pollutants (PCBs, PBDEs, DDXs, HCHs, HCB, Σ PCDD/Fs and Σ DL-PCBs) in blubber samples of bottlenose dolphins from LFK (n = 27) and FCE (n = 24). PCBs were the major class of compounds found in bottlenose dolphin blubber and were higher in individuals from LFK (Σ 6 PCBs LFK males: 13421 ± 7730 ng.g-1 lipids, Σ 6 PCBs LFK females: 9683 ± 19007 ng.g-1 lipids) than from FCE (Σ 6 PCBs FCE males: 5638 ng.g-1 ± 3627 lipids, Σ 6 PCBs FCE females: 1427 ± 908 ng.g-1 lipids). These levels were lower than previously published data from the southeastern USA. The Σ DL-PCBs were the most prevalent pollutants of dioxin and dioxin like compounds (Σ DL-PCBs LFK: 739 ng.g-1 lipids, Σ DL-PCBs FCE: 183 ng.g-1 lipids) since PCDD/F concentrations were low for both locations (mean 0.1 ng.g-1 lipids for LFK and FCE dolphins). The toxicity equivalences of PCDD/Fs and DL-PCBs expressed as TEQ in LFK and FCE dolphins is mainly expressed by DL-PCBs (81% LFK - 65% FCE). T-Hg concentrations in skin were significantly higher in FCE (FCE median 9314 ng.g-1 dw) compared to LFK dolphins (LFK median 2941 ng.g-1 dw). These bottlenose dolphins concentrations are the highest recorded in the southeastern USA, and may be explained, at least partially, by the biogeochemistry of the Everglades and mangrove sedimentary habitats that create favourable conditions for the retention of mercury and make it available at high concentrations for aquatic predators. [less ▲]

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See detailTracing Migrant-Mothers’ ‘Return’ Narratives in the Mexico-U.S and Peru-Belgium Migratory Circuits.
Vivas Romero, Maria ULg; Sanchez-Martinez, Anabela

in Travaux et recherches dans les amériques du centre (2017)

How do contemporary migrant mothers strategize return to their home countries? And how does the social protections available for their bi-national children in sending and destination countries factor in ... [more ▼]

How do contemporary migrant mothers strategize return to their home countries? And how does the social protections available for their bi-national children in sending and destination countries factor in the decision to return? Through this contribution, we aimed to tackle these questions. We draw from the analysis of two longitudinal migratory careers and argue that our participant’s return decisions were influenced both by their children’s effective access to social protection and their subjective perceptions of ‘good-motherhood’. This Trans-Atlantic comparison shows how different situated-institutional-contexts, cultures of care and motherhood resulted into different patterns of mobility for these women and their families. [less ▲]

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See detailThe Role of Companies in Smart City Initiatives: The Case of Belgium
Andre, Anne-Marie; Crutzen, Nathalie ULg

in Economia (2017)

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See detailUsutu virus, Belgium, 2016
Garigliany, Mutien-Marie ULg; Linden, Annick ULg; Gilliaux, Gautier ULg et al

in Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (2017), 48(1), 116-119

During late summer 2016, in a northwest European region extending over Belgium, the Netherlands and the eastern border of the German state of North Rhine Westphalia, an outbreak of wild bird deaths ... [more ▼]

During late summer 2016, in a northwest European region extending over Belgium, the Netherlands and the eastern border of the German state of North Rhine Westphalia, an outbreak of wild bird deaths occurred similar to those reported on the continent since 1996. Dead birds were necropsied and examined by complementary methods. Pathologic and immunohistological investigations strongly suggested an infection by Usutu virus. Subsequently, genomic segments of the said virus were detected, the virus was isolated and its complete genome was sequenced. The strain, designated Usutu-LIEGE, is a close phylogenetic relative of those isolated in Germany which form a distinct group within the USUV phylogeny, the so-called Europe_3 lineage. Should this outbreak recapitulate the characteristics of those in southwest Germany in 2011 and in/around Vienna (Austria) in 2001, it is expected that specific avian populations in the affected area will face a significant reduction in size for a few years. [less ▲]

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See detailPost-embryonic development of sheepshead minnow Cyprinodon variegatus: a staging tool based on externally visible anatomical traits
Schnitzler, Joseph ULg; Dussenne, Mélanie ULg; Frederich, Bruno ULg et al

in Ichthyological Research (2017), 64

The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse ... [more ▼]

The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse sheepshead minnow post-embryonic development with the goal of providing a generally useful method for staging fish after embryogenesis. Groups of three females and two males were placed in breeding chambers designed for this experiment. More than 100 eggs were collected and maintained in seawater. Embryos were selected under a dissection microscope and placed in incubation dishes (50 per dish) at 26 °C. On day six, embryos hatched and larvae were transferred to 1 L beakers. To define a simplified normalization table for sheepshead minnow development, we measured each fish for its standard length and examined the fish for four externally evident traits: pigmentation pattern, caudal fin morphology, anal fin morphology, and dorsal fin morphology. The four traits were chosen, because they are easily visualized with standard laboratory equipment such as the stereomicroscope and camera. We have provided criteria for staging sheepshead minnows in studies of post-embryonic development. Our data suggest that dorsal and anal fin morphology may serve as a useful phenotype for defining metamorphic climax stages throughout post-embryonic development in C. variegatus. The staging systems we propose should facilitate detailed anatomical and developmental analyses in relation to ecotoxicological studies on potential disruption of the thyroid axis by xenobiotics and endocrine-disrupting compounds. [less ▲]

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