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See detailLa protection sociale du mineur: entre services publics et privés
Gerin, Corinne ULg; Bihain, Luc ULg

in Journal des Tribunaux (2012), 6479

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See detailControlling flux flow dissipation by changing flux pinning in superconducting films
Grimaldi, G; Leo, A; Nigro, A et al

in Applied Physics Letters (2012), 100

We study the flux flow state in superconducting materials characterized by rather strong intrinsic pinning, such as Nb, NbN, and nanostructured Al thin films, in which we drag the superconducting ... [more ▼]

We study the flux flow state in superconducting materials characterized by rather strong intrinsic pinning, such as Nb, NbN, and nanostructured Al thin films, in which we drag the superconducting dissipative state into the normal state by current biasing. We modify the vortex pinning strength either by ion irradiation, by tuning the measuring temperature or by including artificial pinning centers. We measure critical flux flow voltages for all materials and the same effect is observed: switching to low flux flow dissipations at low fields for an intermediate pinning regime. This mechanism offers a way to additionally promote the stability of the superconducting state. [less ▲]

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See detailDetection of copy number variants in the horse genome and examination of their association with recurrent laryngeal neuropathy
Dupuis, Marie-Capucine; Zhang, Zhiyan ULg; Durkin, Keith ULg et al

in Animal Genetics (2012)

We used the data from a recently performed genome-wide association study using the Illumina Equine SNP50 beadchip for the detection of copy number variants (CNVs) and examined their association with ... [more ▼]

We used the data from a recently performed genome-wide association study using the Illumina Equine SNP50 beadchip for the detection of copy number variants (CNVs) and examined their association with recurrent laryngeal neuropathy (RLN), an important equine upper airway disease compromising performance. A total of 2797 CNVs were detected for 477 horses, covering 229 kb and seven SNPs on average. Overlapping CNVs were merged to define 478 CNV regions (CNVRs). CNVRs, particularly deletions, were shown to be significantly depleted in genes. Fifty-two of the 67 common CNVRs (frequency ! 1%) were validated by association mapping, Mendelian inheritance, and/or Mendelian inconsistencies. None of the 67 common CNVRs were significantly associated with RLN when accounting for multiple testing. However, a duplication on chromosome 10 was detected in 10 cases (representing three breeds) and two unphenotyped parents but in none of the controls. The duplication was embedded in an 8-Mb haplotype shared across breeds. [less ▲]

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See detailFaut-il faire la sociologie des singes ?
Servais, Véronique ULg

in SociologieS (en ligne) (2012)

Drawing its examples from the field of ethology and primatology, this paper brings three points to the debate on the naturalization in sociology. The first one insists on the importance of telling apart ... [more ▼]

Drawing its examples from the field of ethology and primatology, this paper brings three points to the debate on the naturalization in sociology. The first one insists on the importance of telling apart what is innate and what is not in the “innate social abilities” that are hypothesized by Kaufmann & Cordonier. The second one shows that when scientists see the animal communication as purely informative, they miss the fact that animals are first of all real beings engaged in affective interactions. They consequently wrongfully end up with animals that “calculate” or “make choices”. The third point looks at some recent work about cooperation in Apes and shows that behavioural scientists tend to assign to the animals themselves social knowledge that is actually situated in the situation. The paper concludes about the boundaries and limitations of biology when it comes to explain social facts in animals. It suggests that social sciences should begin to explore empirically this no man’s land where social and biological facts interact. Doing so, social sciences could go towards specifying “what” is inherited in social competences, and limiting the evolutionary hold on social facts. [less ▲]

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See detailGreen synthesis and antioxidant activity of new PEGylated ferulic acids
Nicks, Francois ULg; Richel, Aurore ULg; Richard, Gaetan ULg et al

in Tetrahedron Letters (2012), 53(19), 2402-2405

PEGylation of ferulic acid is described through a green esterification process involving poly(ethylene glycol) (PEG) with three different average molecular weights (200, 400 and 1000 g/mol) as both ... [more ▼]

PEGylation of ferulic acid is described through a green esterification process involving poly(ethylene glycol) (PEG) with three different average molecular weights (200, 400 and 1000 g/mol) as both reactive and solvent. Esterification with PEG400 and PEG1000 leads to original compounds soluble in all proportions in water. These new compounds display an antioxidant activity similar to that of ferulic acid. [less ▲]

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See detailMicrosatellite polymorphism in Tunisian pomegranates (Punica granatum L.): Cultivar genotyping and identification
Jbir, Rania; Zehdi, Salwa; Hasnaoui, Nejib ULg et al

in Biochemical Systematics & Ecology (2012), 44

Specific microsatellites (SSRs) markers were used to characterize a set of 32 Tunisian pomegranate (Punica granatum L.) cultivars. Using 13 SSR primers, a total of 40 alleles and 46 genotypes have been ... [more ▼]

Specific microsatellites (SSRs) markers were used to characterize a set of 32 Tunisian pomegranate (Punica granatum L.) cultivars. Using 13 SSR primers, a total of 40 alleles and 46 genotypes have been identified. As a result, data proved that a high level of polymorphism characterizes the Tunisian pomegranate germplasm at the DNA level. The derived Neighbour-joining (NJ) dendrogram constructed using DAS genetic distances exhibited a genetic diversity structured independently from the geographical origin of cultivars and their denomination. This result suggested that a common genetic basis may characterize Tunisian pomegranate cultivars despite their phenotypic divergences. Furthermore, based on the multilocus genotypes a cultivar’s identification key has been established and permitted to unambiguously differentiate between varieties. The obtained results are discussed in term of establishment and management of a national collection of pomegranate varieties, conformity checks, identification of homonyms and synonyms, and screening of the local resources. Furthermore, this microsatellite-based key is a first step towards a marker-assisted identification pomegranate database. [less ▲]

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See detailAntibacterial polyelectrolyte micelles for coating stainless steel
Falentin, Céline ULg; Faure, Emilie ULg; Svaldo Lanero, Tiziana ULg et al

in Langmuir (2012), 28(18), 7233-7241

In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged ... [more ▼]

In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged polyelectrolytes micelles doped with silver based nanoparticles with a polyanion. The micelles are formed by electrostatic interaction between two oppositely charged polymers, a polycation bearing 3,4-dihydroxyphenylalanine units (DOPA, a major component of natural adhesives) and a polyanion (poly(styrene sulfonate), PSS) without using any block copolymer. DOPA units are exploited for their well-known ability to anchor to stainless steel and to form and stabilize biocidal silver nanoparticles (Ag0). The chlorine counter-anion of the polycation forms and stabilizes biocidal silver chloride nanoparticles (AgCl). We demonstrate that two layers of micelles (alternated by PSS) doped by silver particles are enough to impart to the surface a strong antibacterial activity against Gram-negative E. coli. Moreover, micelles that are reservoirs of biocidal Ag+ can be easily reactivated after depletion. This novel water-based approach is convenient, simple and attractive for industrial applications. [less ▲]

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See detailMicrosatellite polymorphism in Tunisian pomegranates (Punica granatum L.): Cultivar genotyping and identification
Jbir, Rania; Zehdi, Salwa; Hasnaoui, Nejib ULg et al

in Biochemical Systematics & Ecology (2012), 44

Specific microsatellites (SSRs) markers were used to characterize a set of 32 Tunisian pomegranate (Punica granatum L.) cultivars. Using 13 SSR primers, a total of 40 alleles and 46 genotypes have been ... [more ▼]

Specific microsatellites (SSRs) markers were used to characterize a set of 32 Tunisian pomegranate (Punica granatum L.) cultivars. Using 13 SSR primers, a total of 40 alleles and 46 genotypes have been identified. As a result, data proved that a high level of polymorphism characterizes the Tunisian pomegranate germplasm at the DNA level. The derived Neighbour-joining (NJ) dendrogram constructed using DAS genetic distances exhibited a genetic diversity structured independently from the geographical origin of cultivars and their denomination. This result suggested that a common genetic basis may characterize Tunisian pomegranate cultivars despite their phenotypic divergences. Furthermore, based on the multilocus genotypes a cultivar’s identification key has been established and permitted to unambiguously differentiate between varieties. The obtained results are discussed in term of establishment and management of a national collection of pomegranate varieties, conformity checks, identification of homonyms and synonyms, and screening of the local resources. Furthermore, this microsatellite-based key is a first step towards a marker-assisted identification pomegranate database. [less ▲]

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See detailAviculture familiale au Bas-Congo, République Démocratique du Congo (RDC)
Moula, Nassim ULg; Detiffe, Nicolas; Farnir, Frédéric ULg et al

in Livestock Research for Rural Development (2012), 24(5),

La République Démocratique du Congo (RDC) souffre, à l’instar d’une majorité de pays africains, d’une précarité alimentaire conséquente. Le développement du secteur de l’élevage y est une pièce importante ... [more ▼]

La République Démocratique du Congo (RDC) souffre, à l’instar d’une majorité de pays africains, d’une précarité alimentaire conséquente. Le développement du secteur de l’élevage y est une pièce importante de la stratégie de lutte contre cette insécurité alimentaire, par l’apport de protéines de haute qualité aux populations pauvres ainsi que plus globalement par la création de richesses et la diversification du secteur agricole. A ce titre, le secteur avicole offre incontestablement, par son cycle de production court, une solution rapide et abordable par le plus grand nombre. Cette étude aborde les contraintes à la production de la poule locale au Bas-Congo. Plusieurs facteurs y sont identifiés, tels que les pathologies, l’alimentation, l’habitat et les prédateurs. L’amélioration de la situation économique et nutritionnelle des paysans de la Province du Bas-Congo peut être envisagée en améliorant le potentiel de production des poulets de race locale. Afin d’y arriver, une attention particulière doit être accordée à une alimentation équilibrée et une meilleure conduite générale de l’élevage, incluant un accès aux soins vétérinaires. L’amélioration génétique des races locales est également une voie envisageable, pour autant que l’adéquation entre l’animal et le cadre de son élevage soit respectée. [less ▲]

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See detailEvidence for a partial epithelial-mesenchymal transition in postnatal stages of rat auditory organ morphogenesis.
Johnen, Nicolas ULg; Francart, Marie-Emilie ULg; Thelen, Nicolas ULg et al

in Histochemistry & Cell Biology (2012)

The epithelial-mesenchymal transition (EMT) plays a crucial role in the differentiation of many tissues and organs. So far, an EMT was not detected in the development of the auditory organ. To determine ... [more ▼]

The epithelial-mesenchymal transition (EMT) plays a crucial role in the differentiation of many tissues and organs. So far, an EMT was not detected in the development of the auditory organ. To determine whether an EMT may play a role in the morphogenesis of the auditory organ, we studied the spatial localization of several EMT markers, the cell-cell adhesion molecules and intermediate filament cytoskeletal proteins, in epithelium of the dorsal cochlea during development of the rat Corti organ from E18 (18th embryonic day) until P25 (25th postnatal day). We examined by confocal microscopy immunolabelings on cryosections of whole cochleae with antibodies anti-cytokeratins as well as with antibodies anti-vimentin, anti-E-cadherin and anti-β-catenin. Our results showed a partial loss of E-cadherin and β-catenin and a temporary appearance of vimentin in pillar cells and Deiters between P8 and P10. These observations suggest that a partial EMT might be involved in the remodelling of the Corti organ during the postnatal stages of development in rat. [less ▲]

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See detailInfluence of artificial pinning on vortex lattice instability in superconducting films
Silhanek, Alejandro ULg; Leo, A.; Grimaldi, G. et al

in New Journal of Physics (2012), 14

In superconducting films under an applied dc current, we analyze experimentally and theoretically the influence of engineered pinning on the vortex velocity at which the flux-flow dissipation undergoes an ... [more ▼]

In superconducting films under an applied dc current, we analyze experimentally and theoretically the influence of engineered pinning on the vortex velocity at which the flux-flow dissipation undergoes an abrupt transition from low to high resistance. We argue, based on a nonuniform distribution of vortex velocity in the sample, that in strongly disordered systems the mean critical vortex velocity for flux-flow instability (i) has a nonmonotonic dependence on magnetic field and (ii) decreases as the pinning strength is increased. These findings challenge the generally accepted microscopic model of Larkin and Ovchinnikov (1979 J. Low. Temp. Phys. 34 409) and all subsequent refinements of this model which ignore the presence of pinning centers. [less ▲]

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See detailAuditory Resting-State Network Connectivity in Tinnitus: a Functionnal MRI Study.
MAUDOUX, Audrey ULg; LEFEBVRE, Philippe ULg; CABAY, Jean-Evrard ULg et al

in PLoS ONE (2012)

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test ... [more ▼]

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI ‘‘resting-state’’ connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physiopathology and suggest that various regions of the brain seem involved in the persistent awareness of the phenomenon as well as in the development of the associated distress. leading to disabling chronic tinnitus. [less ▲]

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See detailIdentification and quantification of concentration-dependent biomarkers in MCF-7/BOS cells exposed to 17β-estradiol by 2-D DIGE and label-free proteomics
Collodoro, Mike ULg; Lemaire, Pascale ULg; Eppe, Gauthier ULg et al

in Journal of Proteomics (2012), in press

This paper reports the identification of biomarkers resulting from the exposure of MCF-7/BOS cells to 17β-estradiol (E2). The biomarkers were identified using 2 independent and complementary techniques, 2 ... [more ▼]

This paper reports the identification of biomarkers resulting from the exposure of MCF-7/BOS cells to 17β-estradiol (E2). The biomarkers were identified using 2 independent and complementary techniques, 2-D DIGE / MALDI-TOF peptide mass fingerprint, and 2-D UPLC-ESI MS/MS. These markers form a preliminary molecular signature that can be used when testing the estrogenic activity of xenobiotics, either pure or in mixtures. [less ▲]

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See detailHST/STIS spectroscopy of the magnetic Of?p star HD 108: the low state at ultraviolet wavelengths
Marcolino, W. L. F.; Bouret, J.-C.; Walborn, N. R. et al

in Monthly Notices of the Royal Astronomical Society (2012), 422

We present the first ultraviolet spectrum of the peculiar, magnetic Of?p star HD 108 obtained in its spectroscopic low state. The new data, obtained with the Space Telescope Imaging Spectrograph (STIS) on ... [more ▼]

We present the first ultraviolet spectrum of the peculiar, magnetic Of?p star HD 108 obtained in its spectroscopic low state. The new data, obtained with the Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope, reveal significant changes compared to IUE spectra obtained in the high state: N Vλ1240, Si IVλ1400 and C IVλ1550 present weaker P Cygni profiles (less absorption) in the new data, while N IVλ1718 absorption is deeper, without the clear wind signature evident in the high state. Such changes contrast with those found in other magnetic massive stars, where more absorption is observed in the resonance doublets when the sightline is close to the plane of the magnetic equator. The new data show also that the photospheric Fe IV forest, at ˜1600-1700 Å, has strengthened compared to previous observations. The ultraviolet variability is large compared to that found in typical, non-magnetic O stars, but moderate when compared to the high-/low-state changes reported in the optical spectrum of HD 108 over several decades. We use non-local thermodynamic equilibrium (non-LTE) expanding-atmosphere models to analyse the new STIS observations. Overall, the results are in accord with a scenario in which the optical variability is mainly produced by magnetically constrained gas, close to the photosphere. The relatively modest changes found in the main ultraviolet wind lines suggest that the stellar wind is not substantially variable on a global scale. Nonetheless, multidimensional radiative-transfer models may be needed to understand some of the phenomena observed. [less ▲]

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See detailTowards an effective asteroseismology of solar-like stars: time-dependent convection effects on pulsation frequencies
Grigahcène, A.; Dupret, Marc-Antoine ULg; Sousa, S. G. et al

in Monthly Notices of the Royal Astronomical Society (2012), 422

Since the early days of helioseismology, adiabatic models have shown their limits for a precise fitting of individual oscillation frequencies. This discrepancy, which also exists for solar-type stars, is ... [more ▼]

Since the early days of helioseismology, adiabatic models have shown their limits for a precise fitting of individual oscillation frequencies. This discrepancy, which also exists for solar-type stars, is known to originate near the surface superadiabatic convective region where the interaction between oscillations and convection is likely to have a large effect on the frequencies. We present an asteroseismic study to address the adequacy of time-dependent convection (TDC) non-adiabatic models to better reproduce the observed individual frequencies. We select, for this purpose, three solar-like stars, in addition to the Sun, to which we fit the observed frequencies in a grid of TDC non-adiabatic models. The best model selection is done by applying a maximum likelihood method. The results are compared to pure adiabatic and near-surface corrected adiabatic models. We show that, first, TDC models give very good agreement for the mode frequencies and average lifetimes. In the solar case, the frequency discrepancy is reduced to <1.75 μHz over 95 per cent of the modes considered. Secondly, TDC models give an asteroseismic insight into the usually unconstrained ad hoc stellar parameters, such as the mixing-length parameter α[SUB]MLT[/SUB]. [less ▲]

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See detailOn the sensitivity of closure phases to faint companions in optical long baseline interferometry
Le Bouquin, Jean-Baptiste; Absil, Olivier ULg

in Astronomy and Astrophysics (2012), 541

We explore the sensitivity and completeness of long baseline interferometric observations for detecting unknown, faint companions around bright unresolved stars. We derive a linear expression for the ... [more ▼]

We explore the sensitivity and completeness of long baseline interferometric observations for detecting unknown, faint companions around bright unresolved stars. We derive a linear expression for the closure phase signature of a faint companion in the high contrast regime (<0.1), and provide a quantitative estimation of the detection efficiency for the currently offered four-telescope configurations at the Very Large Telescope Interferometer. The results are compared to the performances provided by linear and Y-shaped interferometric configurations in order to identify the ideal array. We find that all configurations have a similar efficiency in discovering companions wider than 10mas. Assuming a closure phase accuracy of 0.25deg, that is typical of state-of-the-art instruments, we predict a median dynamic range of up to six magnitudes when stacking observations obtained at five different hour angles. Surveying bright stars to search for faint companions can be considered as an ideal filler programme for modern interferometric facilities because that places few constraints on the choice of the interferometric configuration. [less ▲]

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See detailCharacterizing Lenses and Lensed Stars of High-magnification Single-lens Gravitational Microlensing Events with Lenses Passing over Source Stars
Choi, J.-Y.; Shin, I.-G.; Park, S.-Y. et al

in Astrophysical Journal (2012), 751

We present the analysis of the light curves of nine high-magnification single-lens gravitational microlensing events with lenses passing over source stars, including OGLE-2004-BLG-254, MOA-2007-BLG-176 ... [more ▼]

We present the analysis of the light curves of nine high-magnification single-lens gravitational microlensing events with lenses passing over source stars, including OGLE-2004-BLG-254, MOA-2007-BLG-176, MOA-2007-BLG-233/OGLE-2007-BLG-302, MOA-2009-BLG-174, MOA-2010-BLG-436, MOA-2011-BLG-093, MOA-2011-BLG-274, OGLE-2011-BLG-0990/MOA-2011-BLG-300, and OGLE-2011-BLG-1101/MOA-2011-BLG-325. For all of the events, we measure the linear limb-darkening coefficients of the surface brightness profile of source stars by measuring the deviation of the light curves near the peak affected by the finite-source effect. For seven events, we measure the Einstein radii and the lens-source relative proper motions. Among them, five events are found to have Einstein radii of less than 0.2 mas, making the lenses very low mass star or brown dwarf candidates. For MOA-2011-BLG-274, especially, the small Einstein radius of θ[SUB]E[/SUB] ~ 0.08 mas combined with the short timescale of t [SUB]E[/SUB] ~ 2.7 days suggests the possibility that the lens is a free-floating planet. For MOA-2009-BLG-174, we measure the lens parallax and thus uniquely determine the physical parameters of the lens. We also find that the measured lens mass of ~0.84 M [SUB]&sun;[/SUB] is consistent with that of a star blended with the source, suggesting that the blend is likely to be the lens. Although we did not find planetary signals for any of the events, we provide exclusion diagrams showing the confidence levels excluding the existence of a planet as a function of the separation and mass ratio. [less ▲]

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See detailThe Struve-Sahade effect in the optical spectra of O-type binaries. I. Main-sequence systems (Corrigendum)
Linder, N.; Rauw, Grégor ULg; Sana, H. et al

in Astronomy and Astrophysics (2012), 541

Not Available.

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See detailThe HARPS search for southern extra-solar planets XXXV. Super-Earths around the M-dwarf neighbors Gl433 and Gl667C
Delfosse, X.; Bonfils, X.; Forveille, T. et al

in Astronomy and Astrophysics (2012), 553

Context. M dwarfs have often been found to have super-Earth planets with short orbital periods. These stars are thus preferential targets in searches for rocky or ocean planets in the solar neighborhood ... [more ▼]

Context. M dwarfs have often been found to have super-Earth planets with short orbital periods. These stars are thus preferential targets in searches for rocky or ocean planets in the solar neighborhood. Aims: Our research group recently announced the discovery of one and two low-mass planets around the M1.5V stars Gl 433 and Gl 667C, respectively. We found these planets with the HARPS spectrograph on the ESO 3.6-m telescope at La Silla Observatory, from observations obtained during the guaranteed time observing program of that instrument. Methods: We obtained additional HARPS observations of those two stars, for a total of 67 and 179 radial velocity measurements for Gl 433 and Gl 667C, respectively, and present here an orbital analysis of these extended data sets and our main conclusions about both planetary systems. Results: One of the three planets, Gl 667Cc, has a mass of only M2sini ~ 4.25 M⊕ and orbits in the central habitable zone of its host star. It receives only 10% less stellar energy from Gl 667C than the Earth receives from the Sun. However, planet evolution in the habitable zone can be very different if the host star is a M dwarf or a solar-like star, without necessarily questioning the presence of water. The two other planets, Gl 433b and Gl 667Cb, both have M2sini of ~5.5 M⊕ and periods of ~7 days. The radial velocity measurements of both stars contain longer timescale signals, which we fit with longer period Keplerians. For Gl 433, the signal probably originates in a magnetic cycle, while data of longer time span will be needed before conclusive results can be obtained for Gl 667C. The metallicity of Gl 433 is close to solar, while Gl 667C is metal poor with [Fe/H] ~ -0.6. This reinforces the recent conclusion that the occurrence of super-Earth planets does not strongly correlate with the stellar metallicity. [less ▲]

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See detailTransiting exoplanets from the CoRoT space mission. XXII. CoRoT-16b: a hot Jupiter with a hint of eccentricity around a faint solar-like star
Ollivier, M; Gillon, Michaël ULg; Santerne, A et al

in Astronomy and Astrophysics (2012), 541

<BR /> Aims: We report the discovery of CoRoT-16b, a low density hot jupiter that orbits a faint G5V star (mV = 15.63) in 5.3523 ± 0.0002 days with slight eccentricity. A fit of the data with no a priori ... [more ▼]

<BR /> Aims: We report the discovery of CoRoT-16b, a low density hot jupiter that orbits a faint G5V star (mV = 15.63) in 5.3523 ± 0.0002 days with slight eccentricity. A fit of the data with no a priori assumptions on the orbit leads to an eccentricity of 0.33 ± 0.1. We discuss this value and also derive the mass and radius of the planet. <BR /> Methods: We analyse the photometric transit curve of CoRoT-16 given by the CoRoT satellite, and radial velocity data from the HARPS and HIRES spectrometers. A combined analysis using a Markov chain Monte Carlo algorithm is used to get the system parameters. <BR /> Results: CoRoT-16b is a 0.535 -0.083/+0.085 M[SUB]J[/SUB], 1.17 -0.14/+0.16 R[SUB]J[/SUB] hot Jupiter with a density of 0.44 -0.14/+0.21 g cm[SUP]-3[/SUP]. Despite its short orbital distance (0.0618 ± 0.0015 AU) and the age of the parent star (6.73 ± 2.8 Gyr), the planet orbit exhibits significantly non-zero eccentricity. This is very uncommon for this type of objects as tidal effects tend to circularise the orbit. This value is discussed taking into account the characteristics of the star and the observation accuracy. The CoRoT space mission, launched on December 27, 2006, has been developed and is operated by the CNES with the contribution of Austria, Belgium, Brasil, ESA, Germany, and Spain.Observations made with the HARPS spectrograph at ESO La Silla Observatory (HARPS programs 083.C-0186 and 184.C-0639) and the HIRES spectrograph at the Keck Observatory (NASA-Keck programs N035Hr, N143Hr and N095Hr). [less ▲]

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See detailLes migraines: des gènes à l'environnement
MAGIS, Delphine ULg; Schoenen, Jean ULg

in Revue Médicale de Liège (2012), 67(5-6), 349-358

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See detailTeaching and learning normal gynecological ultrasonography using simple virtual reality objects: a proposal for a standardized approach
Tutschek, Boris; CHANTRAINE, Frédéric ULg; Tercanli, Sevgi

in Ultrasound in Obstetrics & Gynecology (2012), 39

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See detailLa transaction pénale de droit commun - La culture judiciaire belge garde-t-elle son âme ?
Masset, Adrien ULg; Forthomme, Marie ULg

in Justine (2012), (33), 10-15

Fruit d’une réflexion initiale touchant au domaine du secret bancaire et au droit pénal des affaires, c’est une réforme finalement plus large qu’a instaurée la loi du 14 avril dernier, complétée de la loi ... [more ▼]

Fruit d’une réflexion initiale touchant au domaine du secret bancaire et au droit pénal des affaires, c’est une réforme finalement plus large qu’a instaurée la loi du 14 avril dernier, complétée de la loi de réparation du 11 juillet 2011. Qualifiée par certains – à juste titre – de « révolution », la loi modifie entre autres la matière de la transaction pénale de manière assez surprenante. Première analyse critique d’une réforme en deux temps peu banale… [less ▲]

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See detailPhysicochemical properties of pH-controlled polyion complex (PIC) micelles of poly(acrylic acid)-based double hydrophilic block copolymers and various polyamines
Warnant, Jérôme; Marcotte, N.; Reboul, J. et al

in Analytical and Bioanalytical Chemistry (2012), 403

The physicochemical properties of polyion complex (PIC) micelles were investigated in order to characterize the cores constituted of electrostatic complexes of two oppositely charged polyelectrolytes. The ... [more ▼]

The physicochemical properties of polyion complex (PIC) micelles were investigated in order to characterize the cores constituted of electrostatic complexes of two oppositely charged polyelectrolytes. The pH-sensitive micelles were obtained with double hydrophilic block copolymers containing a poly(acrylic acid) block linked to a modified poly(ethylene oxide) block and various polyamines (polylysine, linear and branched polyethyleneimine, polyvinylpyridine, and polyallylamine). The pH range of micellization in which both components are ionized was determined for each polyamine. The resulting PIC micelles were characterized using dynamic light scattering and smallangle X-ray scattering experiments (SAXS). The PIC micelles presented a core–corona nanostructure with variable polymer density contrasts between the core and the corona, as revealed by the analysis of the SAXS curves. It was shown that PIC micelle cores constituted by polyacrylate chains and polyamines were more or less dense depending on the nature of the polyamine. It was also determined that the density of the cores of the PIC micelles depended strongly on the nature of the polyamine. These homogeneous cores were surrounded by a large hairy corona of hydrated polyethylene oxide block chains. Auramine O (AO) was successfully entrapped in the PIC micelles, and its fluorescence properties were used to get more insight on the core properties. Fluorescence data confirmed that the cores of such micelles are quite compact and that their microviscosity depended on the nature of the polyamine. The results obtained on these core–shell micelles allow contemplating a wide range of applications in which the AO probe would be replaced by various cationic drugs or other similarly charged species to form drug nanocarriers or new functional nanodevices. [less ▲]

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See detailTrends in hip fracture incidence and in the prescription of anti-osteoporosis medications during same time period in Belgium (2000-2007)
Hiligsmann, Mickaël ULg; Bruyère, Olivier ULg; Roberfroid, Dominique et al

in Arthritis Care & Research (2012), 64(5), 744-750

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See detailSe réaliser comme sujet dans un atelier-théâtre pour tenter de « s’en sortir ». Mises en scène de tensions au sein d’une politique de la subjectivité
Brahy, Rachel ULg; Vrancken, Didier ULg

in SociologieS (2012)

Partant d’un terrain d’investigation spécifique, l’atelier-théâtre, les auteurs proposent d’interroger les manières dont s’opère la mise au travail du sujet sur lui-même et plus précisément, d’en saisir ... [more ▼]

Partant d’un terrain d’investigation spécifique, l’atelier-théâtre, les auteurs proposent d’interroger les manières dont s’opère la mise au travail du sujet sur lui-même et plus précisément, d’en saisir les socles techniques et anthropologiques. Dans un premier temps, ils resituent le dispositif théâtral au cœur des évolutions actuelles des politiques sociales. Dans un second temps, ils s’attachent à la description des pratiques d’entrée en subjectivité à partir d’un double travail, tout en soulignant les fondements anthropologiques et sociologiques autour d’un « existentialisme du défi » amenant des publics précarisés à tenter de s’en sortir. Enfin, sont soulignées les limites, tensions et paradoxes de ces dispositifs créatifs. Au terme de cette analyse, le travail en atelier-théâtre, impulsé par des comédiens-animateurs auprès de personnes fragilisées, apparaît ouvrir une voie féconde pour une meilleure connaissance des « politiques de la subjectivité ». [less ▲]

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See detailSketched by themselves. The panorama tested by the ‘‘panoramic’’
Stienon, Valérie ULg; Preiss, Nathalie

in Interférences Littéraires = Literaire Interferenties (2012), 8

Examining the pertinence of the notion “panoramic literature”, famously used by Walter Benjamin in a series of studies on nineteenth century manners, on the basis on a French, Belgian, English, German ... [more ▼]

Examining the pertinence of the notion “panoramic literature”, famously used by Walter Benjamin in a series of studies on nineteenth century manners, on the basis on a French, Belgian, English, German, Spanish and Austrian corpus: that is what is at stake in this issue. Benjamin’s heuristic model, drawn from the spectacle of the panorama, seems to capture the ‘scopic pulsion’ which is connected to the advent of the social democratic state and which, underlying these texts, manifests itself in effects of specularity and reflexivity. By its unifying vocation, the model also brings to light another dimension of these texts, namely a characteristic dialectic of similarity and difference, of individuality and universality, inherited from the Enlightenment and arguably also indebted to the optical illusion. In returning to this notion, the present issue engages in a critique of panoramic reason, which is also a critique of critical reason in its analysis of the moment when, in each of the countries under consideration, a ‘panoramic literature’ constitutes itself as an object of study and a literary-historical question. The issue hence forms both the antechamber of and the springboard for an upcoming site, “Sociorama”, which will be devoted to interdisciplinary research on international “panoramic” literature. [less ▲]

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See detailSuccéder en Contexte Postcolonial Africain: l'ambigüité chiffrée au travers de l'exemple camerounais
Bomda, Joseph ULg; Fonkeng Epah, George; Dardenne, Benoît ULg et al

in Revue Européenne de Psychologie et de Droit (2012)

En matière culturelle, l’Africain postcolonial est partagé entre les normes traditionnelles (ou ancestrales) et modernes (ou héritées du colon). Si la description de cette dualité abonde dans la ... [more ▼]

En matière culturelle, l’Africain postcolonial est partagé entre les normes traditionnelles (ou ancestrales) et modernes (ou héritées du colon). Si la description de cette dualité abonde dans la littérature, la question du taux de connaissance de cette dualité, de son acceptation et de sa défense préoccupe très peu. Pourtant, elle devrait permettre de connaitre l’étendue de l’ambigüité qui anime les populations. Cet article répond à ce déficit et présente un état des lieux auprès de 1013 victimes du choc de normes successorales (tradition vs. modernité) en contexte postcolonial camerounais. Au préalable, les 6 points d’opposition entre les deux normes sont présentés. L’historique de la dualité juridique à l’origine de ces contrastes et le fondement psycho-anthropologique des visions du monde fondatrices de l’une et l’autre norme permettent de cerner l’irréductibilité des oppositions. [less ▲]

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See detailExperimental method for the assessment of agricultural spray retention based on high-speed imaging of drop impact on a synthetic superhydrophobic surface
Massinon, Mathieu ULg; Lebeau, Frédéric ULg

in Biosystems Engineering (2012), 112(1), 56-64

Spray retention is a critical stage in pesticide application since non-retained drops can result in reduced efficacy, economic loss and environmental contamination. Current methods of retention assessment ... [more ▼]

Spray retention is a critical stage in pesticide application since non-retained drops can result in reduced efficacy, economic loss and environmental contamination. Current methods of retention assessment are based either on field experiments or laboratory studies. The former are usually performed on whole plants under realistic spray application conditions but offer no insight into the physics behind the process whilst the latter mainly focus on drop impact physics but are usually restricted to unrealistically low drop speeds. The aim of the paper is to devise an experimental method to investigate retention at drop scale level as a function of operational parameters but under controlled realistic conditions. A device based on highspeed video was developed to study retention on a synthetic superhydrophobic surface for a moving agricultural nozzle. The sizes and velocities of the drops generated were measured immediately before impact using image analysis. Impact class proportions were established and transition boundaries between impact outcomes were quantified using Weber number. Two contrasting experiments were performed to investigate the ability of method to detect small parametric changes. The insignificant changes in spray pattern that occur from pressure changes, did not significantly affect impact class boundaries, but changed the proportion of drops in each class because of size and velocity variations. The use of a surfactant reduced the volume median diameter of the spray, increased impact speed and changed the impact class boundaries. The method should allow a precise parametric investigation of spray retention in laboratory and close to field conditions. [less ▲]

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See detailLe diagramme entre perception visuelle et mathématique
Dondero, Maria Giulia ULg

in Visible (2012), 8

Ce texte s’interroge sur la spécificité de l’image scientifique par rapport à d’autres outils de représentation et d’autres statuts de l’image – tel que le statut artistique. Il propose des éléments de ... [more ▼]

Ce texte s’interroge sur la spécificité de l’image scientifique par rapport à d’autres outils de représentation et d’autres statuts de l’image – tel que le statut artistique. Il propose des éléments de réflexion à partir de trois questions principales : 1) est-ce qu’on peut élaborer une définition de l’image scientifique qui soit commune à toutes les disciplines scientifiques ? 2) Quels types de rapport s’établissent entre les images scientifiques et les images artistiques ? S’agit-il d’une différence ontologique ou bien pragmatique ? 3) Est-ce que le dispositif de l’image trouve son terme opposé dans le texte verbal, suivant l’ancienne distinction entre analogue et digital ? Est-ce que par contre l’image trouve son terme opposé dans le langage formel des mathématiques ? [less ▲]

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See detailEffect of Cognitive Load on Working Memory Forgetting in Aging
Baumans, Christine ULg; Adam, Stéphane ULg; Seron, Xavier

in Experimental Psychology (2012), 22

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See detailLes maladies complexes : l'hypertension artérielle
Krzesinski, Jean-Marie ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2012), 67(5-6), 279-285

Essential hypertension, defined as a blood pressure equal to or above 140/90 mmHg, is a common (25% of the population), but complex disease the phenotype of which results from interactions between ... [more ▼]

Essential hypertension, defined as a blood pressure equal to or above 140/90 mmHg, is a common (25% of the population), but complex disease the phenotype of which results from interactions between numerous genes and environmental factors. The role attributable to genetic factors amounts to some 25% among hypertensive families, but can reach 65% when monozygotic twins are compared. In the present state of our knowledge, there is no hope to obtain a genetic test of value for the diagnosis and prognosis of hypertension. An individualized environmental approach, applied early in life, is the only worhtwhile attitude. Nonetheless, in the presence of a subject with still normal blood pressure values, but with a family history of hypertension, the physician should firmly recommend an appropriate hygieno-dietetic lifestyle with a view to lower blood pressure, or retard the development of arterial hypertension. [less ▲]

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See detailEvolution du champ de la Santé mentale en Belgique: de l’asile vers les réseaux et circuits de soins
Thunus, Sophie ULg; Cerfontaine, Gaëtan ULg; Schoenaers, Frédéric ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2012), 72

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See detailLa réécriture du référentiel des compétences terminales et savoirs communs dans l’enseignement qualifiant : enjeux et opportunités
Jadoulle, Jean-Louis ULg

in Puzzle. Revue du Centre interfacultaire de formation des enseignants de l'ULg (2012), n°31

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See detailBacillus licheniformis BlaR1 L3 Loop Is a Zinc Metalloprotease Activated by Self-Proteolysis
Berzigotti, Stépanie; Benlafya, Kamal; Sépulchre, Jérémy et al

in PLoS ONE (2012)

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See detailImportant differences in management policies for children with end-stage renal disease in the Netherlands and Belgium--report from the RICH-Q study.
Tromp, Wilma F.; Schoenmaker, Nikki J.; van der Lee, Johanna H. et al

in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2012), 27(5), 1984-92

BACKGROUND: The low prevalence of childhood end-stage renal disease and the small centre sizes have been a barrier for clinical studies and the development of evidence-based guidelines for chronic renal ... [more ▼]

BACKGROUND: The low prevalence of childhood end-stage renal disease and the small centre sizes have been a barrier for clinical studies and the development of evidence-based guidelines for chronic renal replacement therapy (cRRT) in children. Few data exist on the quality of care for these patients and the applicability of existing guidelines. The aim of this study is to quantify variation in treatment policies and actually delivered care in nine centres that deliver cRRT for children. METHODS: We surveyed treatment policies in all nine centres in the Netherlands and Belgium and compared them with the actually provided therapies and with recommendations from available guidelines. Data on treatment policies were gathered by questionnaires; actually provided care and outcomes were registered prospectively from 2007 to 2010. RESULTS: Data on policies and actual patient care were obtained from all nine centres. We found relevant differences between centres in treatment policies on various topics, e.g. estimated glomerular filtration rate threshold as an indication for initiation of cRRT, preferred initial mode of cRRT, peritoneal dialysis catheter care, haemodialysis frequency and vascular access. Discrepancies were seen between stated treatment policies and actual performed therapies. For the majority of policies, no evidence-based guidelines are available. CONCLUSIONS: Health care disparities exist due to large and unwanted variation in treatment policies between hospitals providing cRRT for children. Delivered care does not live up to stated policies, for which clear and internationally accepted guidelines are lacking. [less ▲]

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See detailMinimal Lepton Flavor Violating Realizations of Minimal Seesaw Models.
Aristizabal Sierra, Diego ULg; Degée, Audrey ULg; Kamenik, Jernej F.

in Journal of High Energy Physics [=JHEP] (2012), JHEP 1207 (2012) 135(2012), 135-156

We study the implications of the global U(1)R symmetry present in minimal lepton flavor violating implementations of the seesaw mechanism for neutrino masses. In the context of minimal type I seesaw ... [more ▼]

We study the implications of the global U(1)R symmetry present in minimal lepton flavor violating implementations of the seesaw mechanism for neutrino masses. In the context of minimal type I seesaw scenarios with a slightly broken U(1)R, we show that, depending on the R-charge assignments, two classes of generic models can be identi fied. Models where the right-handed neutrino masses and the lepton number breaking scale are decoupled, and models where the parameters that slightly break the U(1)R induce a suppression in the light neutrino mass matrix. We show that within the fi rst class of models, contributions of right-handed neutrinos to charged lepton flavor violating processes are severely suppressed. Within the second class of models we study the charged lepton flavor violating phenomenology in detail, focusing on \ mu->e \gamma , \mu->3e and \mu- e conversion in nuclei. We show that sizable contributions to these processes are naturally obtained for right-handed neutrino masses at the TeV scale. We then discuss the interplay with the eff ects of the right- handed neutrino interactions on primordial B- L asymmetries,fi nding that sizable right-handed neutrino contributions to charged lepton flavor violating processes are incompatible with the requirement of generating (or even preserving preexisting) B-L asymmetries consistent with the observed baryon asymmetry of the Universe. [less ▲]

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See detailImaging artificial salt water infiltration using electrical resistivity tomography constrained by geostatistical data
Hermans, Thomas ULg; Vandenbohede, Alexander; Lebbe, Luc et al

in Journal of Hydrology (2012), 438-439

Electrical resistivity tomography is a well-known technique to monitor fresh-salt water transitions. In such environments, boreholes are often used to validate geophysical results but rarely used to ... [more ▼]

Electrical resistivity tomography is a well-known technique to monitor fresh-salt water transitions. In such environments, boreholes are often used to validate geophysical results but rarely used to constrain the geoelectrical inversion. To estimate the extent of salt water infiltration in the dune area of a Natural Reserve (Westhoek, Belgium), electrical resistivity tomography profiles were carried out together with borehole electromagnetic measurements. The latter were used to calculate a vertical variogram, representative of the study site. Then, a geostatistical constraint, in the form of an a priori model covariance matrix based on the variogram, was imposed as regularization to solve the electrical inverse problem. Inversion results enabled to determine the extension of the salt water plume laterally and at depth, but also to estimate the total dissolved solid content within the plume. These results are in agreement with the hydrogeological data of the site. A comparison with borehole data showed that the inversion results with geostatistical constraints are much more representative of the seawater body (in terms of total dissolved solids, extension and height) than results using standard smoothness-constrained inversion. The field results obtained for the Westhoek site emphasize the need to go beyond standard smoothness-constrained images and to use available borehole data as prior information to constrain the inversion. [less ▲]

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See detailLeptogenesis in flavor models with type I and II seesaws
Aristizabal Sierra, Diego ULg; Bazzocchi, Federica; de Medeiros Varzielas, Ivo

in Nuclear Physics B (2012)

In type I seesaw models with flavor symmetries accounting for the lepton mixing angles the CP asymmetry in right-handed neutrino decays vanishes in the limit in which the mixing pattern is exact. We study ... [more ▼]

In type I seesaw models with flavor symmetries accounting for the lepton mixing angles the CP asymmetry in right-handed neutrino decays vanishes in the limit in which the mixing pattern is exact. We study the implications that additional degrees of freedom from type II seesaw may have for leptogenesis in such a limit. We classify in a model independent way the possible realizations of type I and II seesaw schemes, differentiating between classes in which leptogenesis is viable or not. We point out that even with the interplay of type I and II seesaws there are generic classes of minimal models in which the CP asymmetry vanishes. Finally we analyze the generation of the lepton asymmetry by solving the corresponding kinetic equations in the general case of a mild hierarchy between the light right-handed neutrino and the scalar triplet masses. We identify the possible scenarios in which leptogenesis can take place. [less ▲]

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See detailAutécologie du frêne commun (Fraxinus excelsior L.) et du frêne oxyphylle (Fraxinus angustifolia Vahl)
Marty, Pauline; Larrieu, Laurent; Claessens, Hugues ULg et al

in Forêt-Entreprise (2012), (204), 9-12

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See detailCroqués par eux-mêmes. Le panorama à l’épreuve du panoramique
Stienon, Valérie ULg; Preiss, Nathalie

in Interférences Littéraires = Literaire Interferenties (2012), 8

Interroger la pertinence de la notion de « littérature panoramique », appliquée par Walter Benjamin à un ensemble composite d’études de moeurs du XIXe siècle, à partir de corpus français, belge, anglais ... [more ▼]

Interroger la pertinence de la notion de « littérature panoramique », appliquée par Walter Benjamin à un ensemble composite d’études de moeurs du XIXe siècle, à partir de corpus français, belge, anglais, belge, allemand, espagnol, autrichien : tel est l’enjeu de ce numéro. Si ce modèle heuristique, emprunté au spectacle du panorama, semble bien rendre compte de la « pulsion scopique », liée à l’avènement de l’état social démocratique, qui sous-tend ces textes et se manifeste par des effets de spécularité et de réflexivité ; si, par sa vocation unifiante, elle met en lumière la dialectique du même et de l’autre, de l’universel et de l’individuel héritée des Lumières, qui les caractérise, elle peut aussi relever de l’illusion d’optique. On se livre donc ici à une critique de la raison panoramique, à une critique aussi de la raison critique en scrutant le moment où, dans chaque pays concerné, la « littérature panoramique » se constitue en objet d’étude et en question. Ce numéro se veut tout à la fois l’antichambre et le tremplin d’un site d’étude interdisciplinaire en préparation, « Sociorama », consacré à la littérature panoramique internationale. [less ▲]

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See detailLes Belges peints par eux-mêmes. Une littérature m(it)oyenne
Stienon, Valérie ULg

in Interférences Littéraires = Literaire Interferenties (2012), 8

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See detailLes premiers grands récits de Comès
Paques, Frédéric ULg

in Liège Museum : Bulletin Trimestriel des Musées de la Ville de Liège (2012)

L'article aborde les débuts de Didier Comès, auteur de bandes dessinées. Il tente de retracer son évolution stylistique jusqu'à la création de l'album "Silence".

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See detailReview of L.O. Juul, Oracular Tales in Pausanias
Pirenne-Delforge, Vinciane ULg

in Histos : the On-line Journal of Ancient Historiography (2012), 6

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See detailLarge-scale identification of selenium metabolites by online size-exclusion-reversed phase liquid chromatography with combined inductively coupled plasma (ICP-MS) and electrospray ionization linear trap-Orbitrap mass spectrometry (ESI-MS(n))
Preudhomme, Hugues; Far, Johann ULg; Gil-Casal, Sandra et al

in Metallomics (2012), 4(5), 422-432

A method was developed for the comprehensive cartography of the selenium metabolites synthesized in the process of conversion of selenite [Se(IV)] into organic compounds and enrichment of yeast with ... [more ▼]

A method was developed for the comprehensive cartography of the selenium metabolites synthesized in the process of conversion of selenite [Se(IV)] into organic compounds and enrichment of yeast with selenium. The number of compounds detected was considerably increased (49) owing to the optimization of the fractionation procedure and the use of UPLC. The increased purity of the minor selenoorganic amino acids and oligopeptides allowed successful on-line de-novo identification based on the exact mass (o1 ppm) and fragmentation (MS2/MS3) mass spectra obtained with high resolution and high mass accuracy. The quality of mass spectra allowed the re-interpretation of previously reported structures of some selenium species. [less ▲]

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See detailOn the numerical integration of rate independent single crystal behavior at large strain
Ben Bettaieb, Mohamed; Débordes, Olivier; Dogui, Abdelwaheb et al

in International Journal of Plasticity (2012), 32-33

This paper presents a new numerical algorithm for the integration of the constitutive equations of a single crystal for finite rate-independent elastoplastic strains. The algorithm addressed in this paper ... [more ▼]

This paper presents a new numerical algorithm for the integration of the constitutive equations of a single crystal for finite rate-independent elastoplastic strains. The algorithm addressed in this paper is dedicated to face-centered-cubic (FCC) crystal structures. Its first feature is a much more efficient and more accurate integration scheme of the constitutive equations compared to previous attempts. This scheme is based on a fully implicit integration procedure, yet it may be transformed easily into an explicit scheme. Determining the set of active slip systems is performed by the use of a combinatorial search procedure, and the determination of the slip rates of the different active slip systems is based on the fixed point method. The second feature of this algorithm stems from the original method used to solve the ambiguity of the possible non-uniqueness of the set of active slip systems. A robust method, based on a small positive perturbation of the critical shear stresses, is proposed to overcome this difficulty. It is worth mentioning that the algorithm developed in this paper is not limited to one particular hardening law or to FCC crystal structures. Rather, it can be used and extended to various hardening laws and crystal structures (e.g. BCC or HCP. . .) in a straightforward manner. The authors demonstrate the performance of the proposed algorithm and illustrate its accuracy and efficiency through various numerical simulations at the single crystal and polycrystal scales. The predicted results obtained from those simulations were compared with those obtained using other numerical techniques and algorithms (i.e., a pseudo-inversion technique and an explicit algorithm). Our numerical predictions are also compared with some numerical and experimental results from other papers. The response of the polycrystal was computed by using the proposed algorithm combined with Taylor’s homogenization scheme, which is used to compute the overall polycrystalline behavior. The paper ends with a statistical study of the influence of the perturbation technique on the response prediction for a single crystal and a polycrystal. [less ▲]

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See detailNanoporous thin films from ionically connected diblock copolymers
Yu, Haizhou; Stoffelbach, François; Detrembleur, Christophe ULg et al

in European Polymer Journal (2012), 48(5), 940-944

An ionically connected polystyrene-block-poly(ethylene oxide) diblock copolymer (PS−+PEO) has been prepared by blending a PEO block functionalized by a dimethylamino group at one extremity with a sulfonic ... [more ▼]

An ionically connected polystyrene-block-poly(ethylene oxide) diblock copolymer (PS−+PEO) has been prepared by blending a PEO block functionalized by a dimethylamino group at one extremity with a sulfonic acid terminated PS block. Proton transfer occurs from the sulfonic acid to the dimethylamino group, resulting in the formation of an ion pair acting as a junction between the two polymer blocks. This copolymer was further used to prepare thin films with a cylindrical morphology consisting of PEO cylinders embedded in a PS matrix and oriented perpendicularly to the film surface. Nanoporous thin films with sulfonate groups on the pore walls have been finally obtained after solvent extraction of the PEO microphases. The presence of those sulfonate groups was evidenced by grafting a positively charged fluorescent dye on the pore walls. [less ▲]

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See detailL'animal dans le soin : entre théories et pratiques
Delfour, Fabienne ULg; Servais, Véronique ULg

in ANAE : Approche Neuropsychologique des Apprentissages chez l'Enfant (2012), 24 - tome II(117), 199-205

In this small form of clear text, we propose an argument that could allow our view to develop scientific research less mutilating and more fruitful in the vast area of the animal care. Having highlighted ... [more ▼]

In this small form of clear text, we propose an argument that could allow our view to develop scientific research less mutilating and more fruitful in the vast area of the animal care. Having highlighted and commented on the most prominent of the various oral and written presentations that are likely to contribute to this change, we discuss the merits of the use of anthropology and constructivist ethology in their situated perspective. What we propose involves three major changes from the previously dominant research traditions: a true recognition of the animal as a subject, the return of their voice to practitioners and the development of attentive and creative methods of observation and investigation. [less ▲]

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See detailIs the KIID sufficient to associate portfolios to investor profiles?
Hübner, Georges ULg

in Bankers, Markets, Investors [=BMI] (2012), (118), 14-22

With the Key Investor Information Document (KID), the new UCITS IV framework brings a useful standardized and simplified scheme to explain the risk of mutual funds to non-professional investors. The ... [more ▼]

With the Key Investor Information Document (KID), the new UCITS IV framework brings a useful standardized and simplified scheme to explain the risk of mutual funds to non-professional investors. The Synthetic Risk and Reward Indicator (SRRI) methodology defines how to assess a volatility equivalent for each type of funds, and recognizes the specificities of various types of investment vehicles in the process. The SRRI rests upon two key principles: (i) risk-volatility mapping: the level of risk can be adequately translated by the volatility of returns; and (ii) reward to volatility: there must be a positive connection between the level of risk borne by the individual investor and the associated reward in terms of returns. We show that the SRRI methodology does not guarantee that these two principles are respected in practice. By forcing any type of risk to be translated into a volatility estimate, the approach overlooks investor’s heterogeneity in the definition of risk. The SRRI synthetic approach is powerless to adequately reflect the trade-off between normal and extreme risks the way it is perceived by individual investors. It also ignores that fund returns are not necessarily only related to volatility. We show that the KID does not replace a proper investment profiling system. The analysis of investor profiles is a necessary complement to the KID in order to provide adequate advice to investors. We provide an approach, based on the linear-exponential utility function, that enables the financial advisor to address the heterogeneity of investors when defining the risk of an investment portfolio. [less ▲]

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See detailSalvatore D'Onofrio, "Le sauvage et son double", compte-rendu
Strivay, Lucienne ULg

in Gradhiva : Revue d'Anthropologie et de Musicologie (2012), 15

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See detailPolémique autour de l'huile de palme: Instantanés d'un secteur en crise
Delacharlerie, Sophie ULg; Poncelet, Céline ULg; Chèné, Christine et al

in Industries Alimentaires et Agricoles (2012), 2012(Mai-Juin), 42-47

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See detailLa Santé mentale à l'épreuve de la qualité
Cerfontaine, Gaëtan ULg

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2012), 72

L’amélioration de la qualité des soins est aujourd’hui une évidence. Objectif partagé de tous et légitime, nul ne semble s’y opposer. Pourtant son application aux soins de santé mentale est moins évidente ... [more ▼]

L’amélioration de la qualité des soins est aujourd’hui une évidence. Objectif partagé de tous et légitime, nul ne semble s’y opposer. Pourtant son application aux soins de santé mentale est moins évidente. Après avoir exposé dans une première partie ce que nous entendons par qualité des soins et ce que ça implique de manière générale, nous exposerons les enjeux particuliers qu’elle soulève en santé mentale. [less ▲]

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See detailLes maladies complexes : l'hypertension artérielle
Krzesinski, Jean-Marie ULg; Saint-Remy, Annie ULg

in Revue Médicale de Liège (2012), 67(5-6), 279-285

Essential hypertension, defined as a blood pressure equal to or above 140/90 mmHg, is a common (25% of the population), but complex disease the phenotype of which results from interactions between ... [more ▼]

Essential hypertension, defined as a blood pressure equal to or above 140/90 mmHg, is a common (25% of the population), but complex disease the phenotype of which results from interactions between numerous genes and environmental factors. The role attributable to genetic factors amounts to some 25% among hypertensive families, but can reach 65% when monozygotic twins are compared. In the present state of our knowledge, there is no hope to obtain a genetic test of value for the diagnosis and prognosis of hypertension. An individualized environmental approach, applied early in life, is the only worhtwhile attitude. Nonetheless, in the presence of a subject with still normal blood pressure values, but with a family history of hypertension, the physician should firmly recommend an appropriate hygieno-dietetic lifestyle with a view to lower blood pressure, or retard the development of arterial hypertension. [less ▲]

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See detailComment la gouvernance d’entreprise influe sur la transparence de l’information
Ajina, Aymen ULg

in Revue Banque = Banque Magazine (2012), 748

Les travaux de recherche d’Aymen Ajina menés sur un échantillon d’environ 150 entreprises cotées à la Bourse de Paris identifient les caractéristiques de leurs systèmes de gouvernance qui influent sur la ... [more ▼]

Les travaux de recherche d’Aymen Ajina menés sur un échantillon d’environ 150 entreprises cotées à la Bourse de Paris identifient les caractéristiques de leurs systèmes de gouvernance qui influent sur la qualité et l’étendue de leur [less ▲]

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See detailPhysical and mechanical properties of black locust (Robinia pseudoacacia) wood grown in Belgium
Pollet, Caroline; Verheyen, Cécile; Hebert, Jacques ULg et al

in Revue canadienne de recherche forestière (2012), 42(5), 831-840

The objective of this study was to characterize black locust (Robinia pseudoacacia L.) wood on the basis of its physical and mechanical properties. The results are compared with those reported in the ... [more ▼]

The objective of this study was to characterize black locust (Robinia pseudoacacia L.) wood on the basis of its physical and mechanical properties. The results are compared with those reported in the literature for English oak (Quercus robur L.), teak (Tectona grandis L. f.), and afzelia (Afzelia sp.), since black locust is likely to be used for the same purposes as the former species. The variations between sites, trees, and radial positions in the trunk were also studied. The physical and mechanical properties of black locust wood were evaluated on clear wood specimens taken from 27 trees distributed over five sites in Wallonia (Belgium) according to Belgian and French standards. Most of the black locust’s mechanical properties are higher than those of oak and teak. The black locust is classified as a “mid-heavy” (734 kg·m–3) and “half-hard” (5.22) wood type with very high resilience (17.2 J·cm–2), modulus of elasticity (15 700 MPa), and tensile strength in static bending (138 MPa). Its resilience is exceptional, higher than that of teak and afzelia, while its modulus of elasticity and bending strength, which surpass those of teak, are comparable with those of afzelia. Black locust shows high total volumetric shrinkage (16%), placing it in the “nervous” class, average tangential (8.8%) and radial shrinkage (5.5%) as well as average axial compressive (63 MPa) and splitting strength (17.8 N·mm–1). No technological incompatibilities would prevent the use of this wood for many value-added purposes (floor, deck, exterior woodwork, and furniture); however, significant shrinkage makes it necessary to condition the wood to its service moisture. [less ▲]

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See detailAction publique et responsabilité gouvernementale : la gestion de la grippe A(H1N1) en 2009
Thoreau, François ULg; Cheneviere, Cédric; Rossignol, Nicolas ULg

in Courrier Hebdomadaire du CRISP (2012), 2138-2139

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See detailFinancial Development and Economic Growth: an Empirical Investigation of the Role of Banks and Institutional Investors
Sougné, Danielle ULg; Cavenaile, Laurent

in Applied Financial Economics (2012), 22(20), 1719-1725

This paper gives a new light on the finance-growth nexus through the investigation of the role of institutional investors as providers of risk diversification in the process of economic growth. We make ... [more ▼]

This paper gives a new light on the finance-growth nexus through the investigation of the role of institutional investors as providers of risk diversification in the process of economic growth. We make use of panel cointegration techniques to study the potential long run relationship between economic growth, banking development and institutional investors in 6 OECD countries. Our results highlight some heterogeneity in the long run relationship between financial development and growth. Institutional investors are shown to support long run economic growth in only 2 countries. We also report a negative long run relationship between both indicators of financial development. [less ▲]

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See detailTrois poètes de Dundee
Pagnoulle, Christine ULg

in Journal des Poètes (2012), 2

Il s'agit de présenter l'œuvre poétiques de trois écrivains liés à la ville côtière écossaise de Dundee, et cela essentiellement par des traductions.

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See detailDemain ne meurt jamais, ou les « écofictions » décryptées. Compte rendu de CHELEBOURG Christian, Les écofictions. Mythologies de la fin du monde »
Stienon, Valérie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2012)

Les mises en garde catastrophistes sur l’avenir écologique de la planète font partie de notre quotidien culturel et audio-visuel depuis une bonne décennie. Des imaginaires multiples en résultent. Ils ... [more ▼]

Les mises en garde catastrophistes sur l’avenir écologique de la planète font partie de notre quotidien culturel et audio-visuel depuis une bonne décennie. Des imaginaires multiples en résultent. Ils constituent les résidus médiatiques de ces discours et représentations convergeant dans l’urgence d’une situation planétaire trop complaisamment présentée comme courant à sa perte. Christian Chelebourg les baptise « écofictions » et les soumet avec virtuosité à une salutaire lecture qui révèle tout à la fois leurs fondements narratifs et leurs implications sociales. [less ▲]

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See detailDéfinition du profil écologique de l'azobé, Lophira alata, une espèce ligneuse africaine de grande importance : synthèse bibliographique et perspectives pour des recherches futures
Biwole, Achille ULg; Bourland, Nils ULg; Daïnou, Kasso ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2012), 16(2), 217-228

Over two decades, labors made in order to promote sustainable management of African tropical forests are tackled to the lack of knowledge about this complex ecosystem. Ecological parameters of timber ... [more ▼]

Over two decades, labors made in order to promote sustainable management of African tropical forests are tackled to the lack of knowledge about this complex ecosystem. Ecological parameters of timber species are no more studied, this complicates long-term sustainable forest management. This literature review related to the ecology and silviculture of ekki, Lophira alata Banks ex C.F.Gaertn. (Ochnaceae), a main African timber species recorded as “vulnerable” in the IUCN Red List, will serve as a study’s case. The planned literature review reveals the doubt about its taxonomy, as well as the lack of understanding concerning its reproductive biology, growth conditions, population dynamics parameters, and the spatial distribution of its genetic diversity. The deficiency of knowledge about its ecological needs and the factors which have historically influenced its population dynamics explain why most silvicultural trails provide hazardous and uncertain results. Remedying these gaps in order to improve its ecological characterization and innovative silvicultural trails, would be a significant contribution to the sustainable management of its populations. [less ▲]

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See detailDetection of disease resistance and susceptibility alleles in pigs using oligonucleotide microarray hybridization
Pastoret, Soumya; Ameels, Hélène; Bossiroy, Frédérique et al

in Journal of Veterinary Diagnostic Investigation (2012), 24(3), 479-488

A multiplex DNA microarray chip aimed at the identification of allelic polymorphisms was developed for simultaneous detection of swine disease resistance genes underlying malignant hyperthermia (RYR ... [more ▼]

A multiplex DNA microarray chip aimed at the identification of allelic polymorphisms was developed for simultaneous detection of swine disease resistance genes underlying malignant hyperthermia (RYR ), postweaning diarrhea, edema disease (FUT1), neonatal diarrhea (MUC4), and influenza (MX1). The on-chip detection was performed with fragmented polymerase chain reaction (PCR)-amplified products. Particular emphasis was placed on the reduction of the number of PCR reactions required. The targets were biotin labeled during the PCR reaction, and the arrays were detected using a colorimetric methodology. Target recognition was provided by specific capture probes designed for each susceptible or resistant allelic variant. Sequencing was chosen as the golden standard to assess chip’s accuracy. All genotypes retrieved from the microarray (476) fitted with sequencing data in spite of the fact that each pig was heterozygote for at least 1 target gene. [less ▲]

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See detailA Semiochemical Slow-release Formulation in a Biological Control Approach to Attract Hoverflies
Heuskin, Stéphanie ULg; Lorge, Stéphanie ULg; Leroy, Pascal ULg et al

in Journal of Environment and Ecology (2012), 3(1), 72-85

E-β-Farnesene, the alarm pheromone of many aphid species, and E-β-caryophyllene are considered as two sesquiterpenes attractive for aphid predators, among which Syrphidae species. Both compounds were ... [more ▼]

E-β-Farnesene, the alarm pheromone of many aphid species, and E-β-caryophyllene are considered as two sesquiterpenes attractive for aphid predators, among which Syrphidae species. Both compounds were formulated in alginate gel beads as slow-release devices in a biological control approach against aphids. Semiochemical diffusion from beads was studied in the laboratory according to abiotic parameters. Efficiency of formulations as hoverfly attractant was demonstrated in field experiments from June to August 2009. The diffusion of semiochemicals from alginate bead formulations was principally limited by high values (>85%) of relative humidity in the air. Temperature also impacts the release of volatile compounds. In field experiments, these two abiotic factors were supposed to highly condition the trapping of hoverflies. These field trappings demonstrated the efficiency of both semiochemical formulations compared to control (formulation without semiochemical) to catch females of Syrphidae during three months. [less ▲]

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See detailUV Spectroscopy of DNA Duplex and Quadruplex Structures in the Gas Phase
Rosu, Frédéric ULg; Gabelica, Valérie ULg; De Pauw, Edwin ULg et al

in Journal of Physical Chemistry A (2012), 116

UV absorption spectroscopy is one of the most widely used methods to monitor nucleic acid folding in solution, but the absorption readout is the weighted average contribution of all species present in ... [more ▼]

UV absorption spectroscopy is one of the most widely used methods to monitor nucleic acid folding in solution, but the absorption readout is the weighted average contribution of all species present in solution. Mass spectrometry, on the other hand, is able to separate constituents of the solution based on their mass, but methods to probe the structure of each constituent are needed. Here, we explored whether gas-phase UV spectroscopy can give an indication of DNA folding in ions isolated by electrospray mass spectrometry. Model DNA single strands, duplexes, and G-quadruplexes were extracted from solution by electrospray; the anions were stored in a quadrupole ion trap and irradiated by a tunable laser to obtain the UV action spectra of each complex. We found that the duplex and quadruplex spectra are significantly different from the spectra of single strands, thereby suggesting that electronic spectroscopy can be used to probe the DNA gas-phase structure and obtain information about the intrinsic properties of high-order DNA structure. [less ▲]

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See detailSeasonal variations in vitamin D levels in melanoma patients: a single-centre prospective pilot comparative study
FAILLA, Valérie ULg; CAVALIER, Etienne ULg; EL HAYDERI, Lara ULg et al

in Journal of the European Academy of Dermatology & Venereology (2012), 26(5), 651-3

BACKGROUND: More than 90% of vitamin D synthesis is dependent on UV exposure. Photosensitive disorders such as lupus erythematosus, protoporphyria and xeroderma require strict sun avoidance, and vitamin D ... [more ▼]

BACKGROUND: More than 90% of vitamin D synthesis is dependent on UV exposure. Photosensitive disorders such as lupus erythematosus, protoporphyria and xeroderma require strict sun avoidance, and vitamin D deficiency has been demonstrated in these patients. Melanoma patients are also instructed to avoid sun exposure and may hence be expected to be vitamin D deficient. MATERIALS AND METHODS: Winter and summer vitamin D levels were compared in a group of melanoma patients (n =61) and age- and phototype-matched controls (n = 53) without photosensitive disorders. RESULTS: Oral supplementary vitamin D intake was reported in 32.7% of the melanoma patients and in 15.1% in the control group. Despite oral supplementation, only 25% of the melanoma patients and the controls presented with vitamin D levels of 30 ng/mL or higher. In non-supplemented subjects in the melanoma and control groups, respectively, mean winter vitamin D levels were below the recommended threshold at 12.6 ng/mL vs. 13.2 ng/mL, respectively, but not statistically different. These values increased significantly in both groups during the summer to 24.6 and 23.8 ng/mL respectively. CONCLUSION: Unexpected, significant increases in vitamin D levels were seen in melanoma patients during summer, suggesting non-adherence with photoprotective measures and reflecting a heliophilic behaviour. Vitamin D supplementation is recommended in melanoma patients during both winter and summer. [less ▲]

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See detailRelating the Chondrocyte Gene Network to Growth Plate Morphology: From Genes to Phenotype
Kerkhofs, Johan ULg; Roberts, Scott J; Luyten, Frank P et al

in PLoS ONE (2012)

During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a ... [more ▼]

During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growth plate network was developed. The network is able to capture the different states (resting, proliferating and hypertrophic) that chondrocytes go through as they progress within the growth plate. In a first corroboration step, the effect of mutations in various signalling pathways of the growth plate network was investigated. [less ▲]

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See detailEffect of concentration temperature on some bioactive compounds and antioxidant proprieties of date syrup
Abbès, Fatma; Besbes, Souhail; Kchaou, Wissal et al

in Food Science & Technology International (2012)

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See detailLa licéité des procédures conventionnelles en récusation d'arbitres
Caprasse, Olivier ULg

in Journal des Tribunaux (2012), (6476), 334-336

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See detailBiomolecule-based antibacterial coating on a stainless steel surface: multilayer film build-up optimization and stability study.
Vreuls, Christelle ULg; Zocchi, Germaine ULg; Vandegaart, Hélène ULg et al

in Biofouling (2012), 28(4), 395-404

The goal of this paper was to establish the durability profile of antibacterial multilayer thin films under storage and usage conditions. Thin films were built on stainless steel (SS) by means of a layer ... [more ▼]

The goal of this paper was to establish the durability profile of antibacterial multilayer thin films under storage and usage conditions. Thin films were built on stainless steel (SS) by means of a layer-by-layer process alternating a negatively charged polyelectrolyte, polyacrylic acid, with a cationic antibacterial peptide, nisin. SS coupons coated with the antibacterial film were challenged under environmental and usage conditions likely to be encountered in real-world applications. The change in antibacterial activity elicited by the challenge was used as an indicator of multilayer film resistance. Antibacterial SS samples could be stored for several weeks at 4°C in ambient air and antibacterial films were resistant to dipping and mild wiping in water and neutral detergent. The multilayer coating showed some weaknesses, however, that need to be addressed. [less ▲]

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See detailLigand Binding Study of Human PEBP1/RKIP: Interaction with Nucleotides and Raf-1 Peptides Evidenced by NMR and Mass Spectrometry
Tavel, Laurette ULg; Jaquillard, Lucie; Karsisiotis, Andreas et al

in PLoS ONE (2012), 7(4): e36187

Background Human Phosphatidylethanolamine binding protein 1 (hPEBP1) also known as Raf kinase inhibitory protein (RKIP), affects various cellular processes, and is implicated in metastasis formation and ... [more ▼]

Background Human Phosphatidylethanolamine binding protein 1 (hPEBP1) also known as Raf kinase inhibitory protein (RKIP), affects various cellular processes, and is implicated in metastasis formation and Alzheimer's disease. Human PEBP1 has also been shown to inhibit the Raf/MEK/ERK pathway. Numerous reports concern various mammalian PEBP1 binding ligands. However, since PEBP1 proteins from many different species were investigated, drawing general conclusions regarding human PEBP1 binding properties is rather difficult. Moreover, the binding site of Raf-1 on hPEBP1 is still unknown. Methods/Findings In the present study, we investigated human PEBP1 by NMR to determine the binding site of four different ligands: GTP, FMN, and one Raf-1 peptide in tri-phosphorylated and non-phosphorylated forms. The study was carried out by NMR in near physiological conditions, allowing for the identification of the binding site and the determination of the affinity constants KD for different ligands. Native mass spectrometry was used as an alternative method for measuring KD values. Conclusions/Significance Our study demonstrates and/or confirms the binding of hPEBP1 to the four studied ligands. All of them bind to the same region centered on the conserved ligand-binding pocket of hPEBP1. Although the affinities for GTP and FMN decrease as pH, salt concentration and temperature increase from pH 6.5/NaCl 0 mM/20°C to pH 7.5/NaCl 100 mM/30°C, both ligands clearly do bind under conditions similar to what is found in cells regarding pH, salt concentration and temperature. In addition, our work confirms that residues in the vicinity of the pocket rather than those within the pocket seem to be required for interaction with Raf-1. [less ▲]

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See detailCornering the axionlike particle explanation of quasar polarizations
Payez, Alexandre ULg

in Physical Review. D : Particles and Fields (2012), 85(8), 087701

In a series of papers, it has been shown that the distribution of polarization position angles for visible light from quasars is not random in extremely large regions of the sky. As explained in a recent ... [more ▼]

In a series of papers, it has been shown that the distribution of polarization position angles for visible light from quasars is not random in extremely large regions of the sky. As explained in a recent article, the measurement of vanishing circular polarization for such quasars is an important problem for a mechanism involving the mixing with axionlike particles in external magnetic fields. In this paper, we stress that a recent report of similar coherent orientations of polarization in radio waves further disfavors the need for such particles, as an effect at these wavelengths would be extremely suppressed or would directly contradict data. [less ▲]

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See detailLa 6e réforme de l'Etat et quelques réflexions sur les perspectives des institutions étatiques belges par-delà la réforme
Behrendt, Christian ULg

in Revue de la Faculté de Droit de l'Université de Liège (2012)

L'article, rédigé en janvier 2012, dresse un panorama actuel de la mise en oeuvre de la 6. Réforme de l'Etat, en pointe les enjeux en termes de calendrier et les difficultés techniques lors de sa mise en ... [more ▼]

L'article, rédigé en janvier 2012, dresse un panorama actuel de la mise en oeuvre de la 6. Réforme de l'Etat, en pointe les enjeux en termes de calendrier et les difficultés techniques lors de sa mise en oeuvre. Il jette d'autre part un regard sur l'évolution possible des institutions étatiques belges à moyen et long terme. [less ▲]

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See detailStatistical interpretation of machine learning-based feature importance scores for biomarker discovery
Huynh-Thu, Vân Anh ULg; Saeys, Yvan; Wehenkel, Louis ULg et al

in Bioinformatics (2012), 28(13), 1766-1774

Motivation: Univariate statistical tests are widely used for biomarker discovery in bioinformatics. These procedures are simple, fast and their output is easily interpretable by biologists but they can ... [more ▼]

Motivation: Univariate statistical tests are widely used for biomarker discovery in bioinformatics. These procedures are simple, fast and their output is easily interpretable by biologists but they can only identify variables that provide a significant amount of information in isolation from the other variables. As biological processes are expected to involve complex interactions between variables, univariate methods thus potentially miss some informative biomarkers. Variable relevance scores provided by machine learning techniques, however, are potentially able to highlight multivariate interacting effects, but unlike the p-values returned by univariate tests, these relevance scores are usually not statistically interpretable. This lack of interpretability hampers the determination of a relevance threshold for extracting a feature subset from the rankings and also prevents the wide adoption of these methods by practicians. Results: We evaluated several, existing and novel, procedures that extract relevant features from rankings derived from machine learning approaches. These procedures replace the relevance scores with measures that can be interpreted in a statistical way, such as p-values, false discovery rates, or family wise error rates, for which it is easier to determine a significance level. Experiments were performed on several artificial problems as well as on real microarray datasets. Although the methods differ in terms of computing times and the tradeoff, they achieve in terms of false positives and false negatives, some of them greatly help in the extraction of truly relevant biomarkers and should thus be of great practical interest for biologists and physicians. As a side conclusion, our experiments also clearly highlight that using model performance as a criterion for feature selection is often counter-productive. [less ▲]

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See detailMismatch between shape changes and ecological shifts during the post-settlement growth of the surgeonfish, Acanthurus triostegus
Frederich, Bruno ULg; Colleye, Orphal ULg; Lepoint, Gilles ULg et al

in Frontiers in Zoology (2012), 9

Background: Many coral reef fishes undergo habitat and diet shifts during ontogeny. However, studies focusing on the physiological and morphological adaptations that may prepare them for these transitions ... [more ▼]

Background: Many coral reef fishes undergo habitat and diet shifts during ontogeny. However, studies focusing on the physiological and morphological adaptations that may prepare them for these transitions are relatively scarce. Here, we explored the body shape variation related to ontogenetic shifts in the ecology of the surgeonfish Acanthurus triostegus (Acanthuridae) from new settler to adult stages at Moorea Island (French Polynesia). Specifically, we tested the relationship between diet and habitat shifts and changes in overall body shape during the ontogeny of A. triostegus using a combination of geometric morphometric methods, stomach contents and stable isotope analysis. Results: After reef settlement, stable isotope composition of carbon and nitrogen revealed a change from a zooplanktivorous to a benthic algae diet. The large amount of algae (> 75% of stomach contents) found in the digestive tract of small juveniles (25–30 mm SL) suggested the diet shift is rapid. The post-settlement growth of A. triostegus is highly allometric. The allometric shape changes mainly concern cephalic and pectoral regions. The head becomes shorter and more ventrally oriented during growth. Morphological changes are directly related to the diet shift given that a small mouth ventrally oriented is particularly suited for grazing activities at the adult stage. The pectoral fin is more anteriorely and vertically positioned and its basis is larger in adults than in juveniles. This shape variation had implications for swimming performance, manoeuvrability, turning ability and is related to habitat shift. Acanthurus triostegus achieves its main transformation of body shape to an adult-like form at size of 35–40 mm SL. Conclusion: Most of the shape changes occurred after the reef colonization but before the transition between juvenile habitat (fringing reef) and adult habitat (barrier reef). A large amount of allometric variation was observed after diet shift from zooplankton to benthic algae. Diet shift could act as an environmental factor favouring or inducing morphological changes. On the other hand, the main shape changes have to be achieved before the recruitment to adult populations and start negotiating the biophysical challenges of locomotion and feeding in wave- and current-swept outer reef habitat. [less ▲]

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See detailMust be trained in geriatric medicine
O'Neill, D; Andersen-Ranberg, K; Cherubini, A et al

in British Medical Journal (2012)

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See detailWASP-44b, WASP-45b and WASP-46b: three short-period, transiting extrasolar planets
Anderson, D. R.; Collier Cameron, A.; Gillon, Michaël ULg et al

in Monthly Notices of the Royal Astronomical Society (2012), 422(3), 1988

We report the discovery of three extrasolar planets that transit their moderately bright (Vmag = 12-13) host stars. WASP-44b is a 0.89-MJup planet in a 2.42-day orbit around a G8V star. WASP-45b is a 1.03 ... [more ▼]

We report the discovery of three extrasolar planets that transit their moderately bright (Vmag = 12-13) host stars. WASP-44b is a 0.89-MJup planet in a 2.42-day orbit around a G8V star. WASP-45b is a 1.03-MJup planet which passes in front of the limb of its K2V host star every 3.13 days. Weak Ca H+K emission seen in the spectra of WASP-45 suggests the star is chromospherically active. WASP-46b is a 2.10-MJup planet in a 1.43-day orbit around a G6V star. Rotational modulation of the light curves of WASP-46 and weak Ca H+K emission in its spectra show the star to be photospherically and chromospherically active. We imposed circular orbits in our analyses as the radial velocity data are consistent with (near-)circular orbits, as could be expected from both empirical and tidal-theory perspectives for such short-period, Jupiter-mass planets. We discuss the impact of fitting for eccentric orbits for these type of planets when not supported by the data. The derived planetary and stellar radii depend on the fitted eccentricity and further studies use these quantities in attempts to understand planet structure, the interdependence of parameters and the relevant physics for extrasolar planets. As such, we recommend exercising caution in fitting the orbits of short period, Jupiter-mass planets with an eccentric orbital model when there is no evidence of non-circularity. [less ▲]

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See detailLocalization of superconductivity in superconductor–electromagnet hybrids
Ataklti, G.W.; Aladyshkin, A.Yu.; Gillijns, W. et al

in Superconductor Science and Technology (2012), 25

We investigate the nucleation of superconductivity in a superconducting Al strip under the influence of the magnetic field generated by a current-carrying Nb wire, perpendicularly oriented and located ... [more ▼]

We investigate the nucleation of superconductivity in a superconducting Al strip under the influence of the magnetic field generated by a current-carrying Nb wire, perpendicularly oriented and located underneath the strip. The inhomogeneous magnetic field, induced by the Nb wire, produces a spatial modulation of the critical temperature Tc, leading to a controllable localization of the superconducting order parameter (OP) wavefunction. We demonstrate that close to the phase boundary Tc(Bext) the localized OP solution can be displaced reversibly by either applying an external perpendicular magnetic field Bext or by changing the amplitude of the inhomogeneous field. [less ▲]

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See detailDBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Close, Pierre ULg; East, Phil; Svejstrup, Barbara et al

in Nature (2012)

Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to ... [more ▼]

Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription, and is greatly affected by the rate of transcript elongation1–3. As the nascent pre-mRNA emerges from transcribing RNA polymerase II (RNAPII), it is assembled into a messenger ribonucleoprotein (mRNP) particle; this is the functional form of the nascent pre-mRNA and determines the fate of the mature transcript4. However, factors that connect the transcribing polymerase with the mRNP particle and help to integrate transcript elongation with mRNA splicing remain unclear. Here we characterize the human interactome of chromatin-associated mRNP particles. This led us to identify deleted in breast cancer 1 (DBC1) and ZNF326 (which we call ZNF-protein interacting with nuclear mRNPs and DBC1 (ZIRD)) as subunits of a novel protein complex—named DBIRD—that binds directly to RNAPII. DBIRD regulates alternative splicing of a large set of exons embedded in (A 1 T)-rich DNA, and is present at the affected exons. RNAinterference- mediated DBIRD depletion results in region-specific decreases in transcript elongation, particularly across areas encompassing affected exons. Together, these data indicate that the DBIRD complex acts at the interface between mRNP particles and RNAPII, integrating transcript elongation with the regulation of alternative splicing. [less ▲]

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See detailPhysical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle
Votion, Dominique ULg; Gnaiger, Erich; Lemieux, Hélène et al

in PLoS ONE (2012), 7(4), 1-12

We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from ... [more ▼]

We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from triceps brachii of healthy horses. The present investigation on horse skeletal muscle has tested the methodology used to study mitochondrial function in muscle microbiopsies by high-resolution respirometry to define reference protocols for horses (from sampling procedure to data analysis). [less ▲]

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See detailClinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers.
Ben Gacem, Riadh; Hachana, Mohamed Ridha ULg; Ziadi, Sonia et al

in Human Pathology (2012)

DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze ... [more ▼]

DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze DNA methyltransferase expression by immunohistochemistry in a series of 94 Tunisian sporadic breast carcinomas. Results were correlated to clinicopathologic parameters and promoter methylation status of 8 tumor suppressor genes (BRCA1, BRCA2, RASSFA1, TIMP3, CDH1, P16, RARβ2, and DAPK). Overexpression of DNA methyltransferase 1, 3a, and 3b was detected in 46.8%, 32%, and 44.7% of cases, respectively. A significant correlation was found between DNA methyltransferase 1 overexpression and Scarff-Bloom-Richardson histologic grade III (P = .01). DNA methyltransferase 3a overexpression was significantly associated with menopausal status (P = .01), Scarff-Bloom-Richardson histologic grade III (P = .0001), estrogen (P = .04) and progesterone (P = .007) receptor negativity, and HER2 overexpression (P = .004). However, DNA methyltransferase 3a overexpression was found less frequently in the luminal A intrinsic breast cancer subtype (9.7%) than in luminal B (53%), HER2 (41%), and triple-negative (50%) subtypes (P = .001). DNA methyltransferase 3b overexpression shows significant correlation with promoter hypermethylation of BRCA1 (P = .03) and RASSFA1 (P = .04) and with the hypermethylator phenotype (more than 4 methylated genes, P = .01). These data suggest that overexpression of various DNA methyltransferases might represent a critical event responsible for the epigenetic inactivation of multiple tumor suppressor genes, leading to the development of aggressive forms of sporadic breast cancer. [less ▲]

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See detailThe inseminating bull and plasma pregnancy-associated glycoprotein levels were related to peripheral leukocyte counts during the late pregnancy/early postpartum period in high-producing dairy cows.
Abdelfatah-Hassan, A.; Almeria, S.; Serrano, B. et al

in Theriogenology (2012), 77(7), 1390-1397

The interest in the immunology and endocrinology aspects of the peripartum in dairy cows has been increasing in the last years, since the animal status during the pre- and postpartum period determines the ... [more ▼]

The interest in the immunology and endocrinology aspects of the peripartum in dairy cows has been increasing in the last years, since the animal status during the pre- and postpartum period determines the subsequent productive and reproductive performance of the animal. At parturition, a drop in the immune functions of the peripheral blood polymorph-nuclear cells (PMN) was observed after a peak of Pregnancy-Associated Glycoproteins (PAGs) and recently, the inseminating bull was found to affect the plasma levels of bovine Pregnancy-Associated Glycoproteins (bovine PAGs) in the pregnant Holstein-Friesian dairy cows. The present work was aimed to determine whether changes in leukocyte counts during the peripartum, indicative of the animal immune status, could be related to the inseminating bull and to the levels of plasma pregnancy-associated glycoproteins (PAGs). Ninety six clinically healthy, single pregnant cows were selected in a commercial dairy herd. Six blood samples (four prepartum and two postpartum) were obtained every two weeks, and total and differential blood cell counts were analyzed. Based on procedures of General Linear Model analysis of variance for repeated measures, the inseminating bull affected counts of total leukocytes and lymphocytes (P<0.001; between-subject effects) throughout the peripartum period. In addition, cows with high plasma levels of PAGs (>900 ρg/µL) on Day 262-268 of gestation had higher numbers of total leukocytes and neutrophils throughout the peripartum period (P<0.001; between-subject effects). Young animals (≤ 1 lactation) had higher total leukocyte and lymphocytes counts than older cows (two or more lactations) throughout the study period. These results showed a clear relationship between the inseminating bull and plasma PAG levels and peripheral leukocyte counts during the peripartum period of dairy cows. [less ▲]

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See detailRéponses du Martin-pêcheur huppé Alcedo cristata à la perturbation de ses sites de nidification
Kisasa Kafutshi, Robert

in Malimbus (2012), 34

From 2004 to 2009, two colonies of Malachite Kingfisher were monitored by ringing the nestlings and adults, counting eggs and observing parental activity at the nests. Results show that 10 % of nests were ... [more ▼]

From 2004 to 2009, two colonies of Malachite Kingfisher were monitored by ringing the nestlings and adults, counting eggs and observing parental activity at the nests. Results show that 10 % of nests were destroyed by people in the Symphonies site as against 78 % in the Monastery site. Consequently, the number of nests available for breeding is lower at Monastery than at Symphonies. The number of fledged chicks per nest at Symphonies was twice that at the Monastery. Site fidelity is higher for the adults in the Symphonies site (26 %) than at the Monastery (11 %). This suggests that the Monastery site is less favourable to the survival of the Malachite Kingfisher than the Symphonies site. The best strategy to protect this species seems to be the maintenance of a good number of nesting sites. [less ▲]

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See detailJanet Frame in East-West Encounters
Gabrielle, Cindy ULg

in Journal of Postcolonial Writing (2012)

Through a close scrutiny of Janet Frame’s life and work, it is my intention in this essay to suggest that Buddhism proved an irresistible magnet for the author’s inquisitive spirit and that it played an ... [more ▼]

Through a close scrutiny of Janet Frame’s life and work, it is my intention in this essay to suggest that Buddhism proved an irresistible magnet for the author’s inquisitive spirit and that it played an important part in the shaping of her poetics. In effect, we shall see under what circumstances Frame’s encounter with the East took place and the extent to which notions such as the empirical mind or knowledge, the Great Death of the ego and the non-duality of the world permeate her oeuvre. The underlying concern in the second part of the essay shall be to buttress the claim that Frame constantly seeks ways through which the infinite and the other can be approached, but not corrupted, by the perceiving self, and that she found in the Buddhist epistemology a pathway towards such alterity. Thus, against the grain of mainstream criticism which maintains that one cannot explore “beyond,” a Buddhist navigation of Frame’s texts leads one to the surprising notion that the unharnessed world (or the infinite) which human beings are unable to embrace is, so to speak, right under their nose so that, between ‘this’ world of limited perceptions and ‘that’ world of the beyond, the boundary is as thick or as thin as the walls of a self-made conceptual prison. [less ▲]

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See detailDifferential usage of NF-kB activating signals by IL-1b and TNF-a in pancreatic beta cells
Ortis, Fernanda; Miani, M; Colli, ML et al

in FEBS Letters (2012), 586

The cytokines interleukin (IL)-1b and tumor necrosis factor (TNF)-a induce b-cell death in type 1 diabetes via NF-kB activation. IL-1b induces a more marked NF-kB activation than TNF-a, with higher ... [more ▼]

The cytokines interleukin (IL)-1b and tumor necrosis factor (TNF)-a induce b-cell death in type 1 diabetes via NF-kB activation. IL-1b induces a more marked NF-kB activation than TNF-a, with higher expression of genes involved in b-cell dysfunction and death. We show here a differential usage of the IKK complex by IL-1b and TNF-a in b-cells. While TNF-a uses IKK complexes containing both IKKa and IKKb, IL-1b induces complexes with IKKa only; this effect is achieved by induction of IKKb degradation via the proteasome. Both IKKg and activation of the TRAF6-TAK1-JNK pathway are involved in IL-1b-induced IKKb degradation. [less ▲]

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See detailDes racines au faîte : Hubert Nyssen romancier
Durand, Pascal ULg

in Bon-A-Tirer : Revue Littéraire en Ligne (2012), 156

Aspects esthétiques et politiques de l'imaginaire romanesque d'Hubert Nyssen, par ailleurs fondateur des éditions Actes Sud.

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See detailGlobal Modeling of X-Ray Spectra Produced in O-type Star Winds
Hervé, Anthony ULg; Rauw, Grégor ULg; Nazé, Yaël ULg et al

in Astrophysical Journal (2012), 748

High-resolution X-ray spectra of O-type stars revealed less wind absorption than expected from smooth winds with conventional mass-loss rates. Various solutions have been proposed, including porous winds ... [more ▼]

High-resolution X-ray spectra of O-type stars revealed less wind absorption than expected from smooth winds with conventional mass-loss rates. Various solutions have been proposed, including porous winds, optically thick clumps, or an overall reduction of the mass-loss rates. The latter has a strong impact on the evolution of the star. Our final goal is to analyze high-resolution X-ray spectra of O-type stars with a multi-temperature plasma model in order to determine crucial stellar and wind parameters such as the mass-loss rate, the CNO abundances, and the X-ray temperature plasma distribution in the wind. In this context we are developing a modeling tool to calculate synthetic X-ray spectra. We present here the main ingredients and physics necessary for such a work. Our code uses the most recent version of the AtomDB emissivities to compute the intrinsic emissivity of the hot plasma as well as the CMFGEN model atmosphere code to evaluate the opacity of the cool wind. Following the comparison between two formalisms of stellar wind fragmentation, we introduce, for the first time in X-rays, the effects of a tenuous inter-clump medium. We then explore the quantitative impact of different model parameters on the X-ray spectra such as the position in the wind of the X-ray emitting plasma. For the first time, we also show that the two formalisms of stellar wind fragmentation yield different results, although the differences for individual lines are small and can probably not be tested with the current generation of X-ray telescopes. As an illustration of our method, we compare various synthetic line profiles to the observed O VIII λ18.97 line in the spectrum of ζ Puppis. We illustrate how different combinations of parameters can actually lead to the same morphology of a single line, underlining the need to analyze the whole spectrum in a consistent way when attempting to constrain the parameters of the wind. [less ▲]

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See detailEvidence for a physically bound third component in HD 150136
Mahy, Laurent ULg; Gosset, Eric ULg; Sana, H et al

in Astronomy and Astrophysics (2012), 540

Context. HD 150136 is one of the nearest systems harbouring an O3 star. Although this system was considered for a long time as a binary, more recent investigations have suggested the possible existence of ... [more ▼]

Context. HD 150136 is one of the nearest systems harbouring an O3 star. Although this system was considered for a long time as a binary, more recent investigations have suggested the possible existence of a third component. <BR /> Aims: We present a detailed analysis of HD 150136 to test its triple nature. In addition, we investigate the physical properties of the individual components of this system. <BR /> Methods: We analysed high-resolution, high signal-to-noise data collected through multi-epoch runs spread over ten years. We applied a disentangling program to refine the radial velocities and to obtain the individual spectra of each star. With the radial velocities, we computed the orbital solution of the inner system, and we describe the main properties of the orbit of the outer star such as the preliminary mass ratio, the eccentricity, and the orbital-period range. With the individual spectra, we determined the stellar parameters of each star by means of the CMFGEN atmosphere code. <BR /> Results: We offer clear evidence that HD 150136 is a triple system composed of an O3V((f[SUP]∗[/SUP]))-3.5V((f[SUP]+[/SUP])), an O5.5-6V((f)), and an O6.5-7V((f)) star. The three stars are between 0-3 Myr old. We derive dynamical masses of about 64, 40, and 35 M[SUB]&sun;[/SUB] for the primary, the secondary and the third components by assuming an inclination of 49° (sin[SUP]3[/SUP]i = 0.43). It currently corresponds to one of the most massive systems in our galaxy. The third star moves with a period in the range of 2950 to 5500 d on an outer orbit with an eccentricity of at least 0.3. However, because of the long orbital period, our dataset is not sufficient to constrain the orbital solution of the tertiary component with high accuracy. <BR /> Conclusions: We confirm there is a tertiary star in the spectrum of HD 150136 and show that it is physically bound to the inner binary system. This discovery makes HD 150136 the first confirmed triple system with an O3 primary star. Table 1 is available in electronic form at <A href="http://www.aanda.org">http://www.aanda.org</A> [less ▲]

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See detailDivision IV / Working Group on Massive Stars
Puls, Joachim; Leitherer, Claus; Owocki, Stan et al

in Transactions of the International Astronomical Union, Series B (2012), 28

Our Working Group (WG) studies massive, luminous stars, both individually and in resolved and unresolved populations, with historical focus on early-type (OB) stars, A-supergiants, and Wolf-Rayet stars ... [more ▼]

Our Working Group (WG) studies massive, luminous stars, both individually and in resolved and unresolved populations, with historical focus on early-type (OB) stars, A-supergiants, and Wolf-Rayet stars. Our group also studies lower mass stars (e.g., central stars of planetary nebulae and their winds) which display features similar or related to those present in massive stars, and thus may improve our understanding of the physical processes occurring in massive stars. In recent years, massive red supergiants that evolve from hot stars have been included into our activities as well. We emphasize the role of massive stars in other branches of astrophysics, particularly regarding the First Stars, long duration Gamma-Ray bursts, formation of massive stars and their feedback on star formation in general, pulsations of massive stars, and starburst galaxies. [less ▲]

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See detailDamping rates of solar-like oscillations across the HR diagram. Theoretical calculations confronted to CoRoT and Kepler observations
Belkacem, K.; Dupret, Marc-Antoine ULg; Baudin, F. et al

in Astronomy and Astrophysics (2012), 540

The space-borne missions CoRoT and Kepler are providing a rich harvest of high-quality constraints on solar-like pulsators. Among the seismic parameters, mode damping rates remains poorly understood and ... [more ▼]

The space-borne missions CoRoT and Kepler are providing a rich harvest of high-quality constraints on solar-like pulsators. Among the seismic parameters, mode damping rates remains poorly understood and are thus barely used to infer the physical properties of stars. Nevertheless, thanks to the CoRoT and Kepler spacecrafts it is now possible to measure damping rates for hundreds of main-sequence and thousands of red-giant stars with unprecedented precision. By using a non-adiabatic pulsation code including a time-dependent convection treatment, we compute damping rates for stellar models that are representative of solar-like pulsators from the main-sequence to the red-giant phase. This allows us to reproduce the observations of both CoRoT and Kepler, which validates our modeling of mode damping rates and thus the underlying physical mechanisms included in the modeling. By considering the perturbations of turbulent pressure and entropy (including the perturbation of the dissipation rate of turbulent energy into heat) by the oscillation in our computation, we succeed in reproducing the observed relation between damping rates and effective temperature. Moreover, we discuss the physical reasons for mode damping rates to scale with effective temperature, as observationally exhibited. Finally, this opens the way for the use of mode damping rates to probe turbulent convection in solar-like stars. [less ▲]

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See detailRossiter-McLaughlin effect measurements for WASP-16, WASP-25 and WASP-31★
Brown, D J A; Cameron, A Collier; Anderson, D R et al

in Monthly Notices of the Royal Astronomical Society (2012)

We present new measurements of the Rossiter-McLaughlin (RM) effect for three Wide Angle Search for transiting Planets (WASP) planetary systems, WASP-16, WASP-25 and WASP-31, from a combined analysis of ... [more ▼]

We present new measurements of the Rossiter-McLaughlin (RM) effect for three Wide Angle Search for transiting Planets (WASP) planetary systems, WASP-16, WASP-25 and WASP-31, from a combined analysis of their complete sets of photometric and spectroscopic data. We find a low-amplitude RM effect for WASP-16 (T[SUB]eff[/SUB]= 5700 ± 150 K), suggesting that the star is a slow rotator and thus of an advanced age, and obtain a projected alignment angle of ?. For WASP-25 (T[SUB]eff[/SUB]= 5750 ± 100 K), we detect a projected spin-orbit angle of λ= 14°.6 ± 6°.7. WASP-31 (T[SUB]eff[/SUB]= 6300 ± 100 K) is found to be well aligned, with a projected spin-orbit angle of λ= 2°.8 ± 3°.1. A circular orbit is consistent with the data for all three systems, in agreement with their respective discovery papers. We consider the results for these systems in the context of the ensemble of RM measurements made to date. We find that whilst WASP-16 fits the hypothesis of Winn et al. that 'cool' stars (T[SUB]eff[/SUB] < 6250 K) are preferentially aligned, WASP-31 has little impact on the proposed trend. We bring the total distribution of the true spin-orbit alignment angle, ψ, up to date, noting that recent results have improved the agreement with the theory of Fabrycky & Tremaine at mid-range angles. We also suggest a new test for judging misalignment using the Bayesian information criterion, according to which WASP-25 b's orbit should be considered to be aligned. [less ▲]

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See detailEuropese rechtspraak : actualia/ actualités: jurisprudence de la Cour de Justice
Durviaux, Ann-Lawrence ULg

in Marchés et Contrats Publics = Overheidsopdrachten en -Overeenkomsten (2012), 1/2012

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See detailEditorial
Bullens, Quentin ULg

in Carnet de Notes sur les Maltraitances Infantiles (2012), 1

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See detailPenser la querelle par la sélection naturelle. Discours et scènes romanesques du struggle for life
Stienon, Valérie ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2012), 10

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See detailL'ancien institut de stomatologie à Bavière en sursis
Charlier, Sébastien ULg

in Nouvelles du Patrimoine (Les) (2012), 135

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See detailVulgariser et distinguer. Stratégies médiatiques autour du discours théorique
Provenzano, François ULg

in Discours et la Langue (Le) (2012), 2(2), 199-209

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See detailImposing periodic boundary condition on arbitrary meshes by polynomial interpolation
Nguyen, Van Dung ULg; Béchet, Eric ULg; Geuzaine, Christophe ULg et al

in Computational Materials Science (2012), 55

In order to predict the effective properties of heterogeneous materials using the finite element approach, a boundary value problem (BVP) may be defined on a representative volume element (RVE) with ... [more ▼]

In order to predict the effective properties of heterogeneous materials using the finite element approach, a boundary value problem (BVP) may be defined on a representative volume element (RVE) with appropriate boundary conditions, among which periodic boundary condition is the most efficient in terms of convergence rate. The classical method to impose the periodic boundary condition requires the identical meshes on opposite RVE boundaries. This condition is not always easy to satisfy for arbitrary meshes. This work develops a new method based on polynomial interpolation that avoids the need of matching mesh condition on opposite RVE boundaries. [less ▲]

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See detailMeasuring the phase of the scattering amplitude with vortex beams
Ivanov, Igor ULg

in Physical Review. D : Particles and Fields (2012), 85(7), 07600110

We show that colliding vortex beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the plane wave scattering amplitude changes with the scattering angle ... [more ▼]

We show that colliding vortex beams instead of (approximate) plane waves can lead to a direct measurement of how the overall phase of the plane wave scattering amplitude changes with the scattering angle. Since vortex beams are coherent superpositions of plane waves with different momenta, their scattering amplitude receives contributions from plane wave amplitudes with distinct kinematics. These contributions interfere, leading to the measurement of their phase difference. Although interference exists for any generic wave packet collision, we show that using vortex beams dramatically enhances sensitivity to the phase in comparison with nonvortex beams. Since the overall phase is inaccessible in a plane wave collision, this measurement would be of great importance for a number of topics in hadronic physics, for example, meson production in the resonance region, physics of nucleon resonances, and small angle elastic hadron scattering. [less ▲]

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See detailNatural Killer cells - role in local tumor growth and metastasis
Langers, Inge ULg; Renoux, Virginie ULg; Thiry, Marc ULg et al

in Biologics: Targets and Therapy (2012)

Historically, the name of Natural Killer (NK) cells came from their natural ability to kill tumor cells in vitro. From the seventies to date, accumulating data highlighted the importance of NK cells in ... [more ▼]

Historically, the name of Natural Killer (NK) cells came from their natural ability to kill tumor cells in vitro. From the seventies to date, accumulating data highlighted the importance of NK cells in host immune response against cancer and in therapy-induced anti-tumor response. The recognition and the lysis of tumor cells by NK cells are regulated by a complex balance of inhibitory and activating signals. This review summarizes NK cell mechanisms to kill cancer cells, their role in host immune responses against tumor growth or metastasis and their implications in anti-tumor immunotherapies via cytokines, antibodies or in combination with other therapies. The regulatory role of NK cells in autoimmunity is also discussed. [less ▲]

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