References of "Scientific journals"      in Complete repository Arts & humanities   Archaeology   Art & art history   Classical & oriental studies   History   Languages & linguistics   Literature   Performing arts   Philosophy & ethics   Religion & theology   Multidisciplinary, general & others Business & economic sciences   Accounting & auditing   Production, distribution & supply chain management   Finance   General management & organizational theory   Human resources management   Management information systems   Marketing   Strategy & innovation   Quantitative methods in economics & management   General economics & history of economic thought   International economics   Macroeconomics & monetary economics   Microeconomics   Economic systems & public economics   Social economics   Special economic topics (health, labor, transportation…)   Multidisciplinary, general & others Engineering, computing & technology   Aerospace & aeronautics engineering   Architecture   Chemical engineering   Civil engineering   Computer science   Electrical & electronics engineering   Energy   Geological, petroleum & mining engineering   Materials science & engineering   Mechanical engineering   Multidisciplinary, general & others Human health sciences   Alternative medicine   Anesthesia & intensive care   Cardiovascular & respiratory systems   Dentistry & oral medicine   Dermatology   Endocrinology, metabolism & nutrition   Forensic medicine   Gastroenterology & hepatology   General & internal medicine   Geriatrics   Hematology   Immunology & infectious disease   Laboratory medicine & medical technology   Neurology   Oncology   Ophthalmology   Orthopedics, rehabilitation & sports medicine   Otolaryngology   Pediatrics   Pharmacy, pharmacology & toxicology   Psychiatry   Public health, health care sciences & services   Radiology, nuclear medicine & imaging   Reproductive medicine (gynecology, andrology, obstetrics)   Rheumatology   Surgery   Urology & nephrology   Multidisciplinary, general & others Law, criminology & political science   Civil law   Criminal law & procedure   Criminology   Economic & commercial law   European & international law   Judicial law   Metalaw, Roman law, history of law & comparative law   Political science, public administration & international relations   Public law   Social law   Tax law   Multidisciplinary, general & others Life sciences   Agriculture & agronomy   Anatomy (cytology, histology, embryology...) & physiology   Animal production & animal husbandry   Aquatic sciences & oceanology   Biochemistry, biophysics & molecular biology   Biotechnology   Entomology & pest control   Environmental sciences & ecology   Food science   Genetics & genetic processes   Microbiology   Phytobiology (plant sciences, forestry, mycology...)   Veterinary medicine & animal health   Zoology   Multidisciplinary, general & others Physical, chemical, mathematical & earth Sciences   Chemistry   Earth sciences & physical geography   Mathematics   Physics   Space science, astronomy & astrophysics   Multidisciplinary, general & others Social & behavioral sciences, psychology   Animal psychology, ethology & psychobiology   Anthropology   Communication & mass media   Education & instruction   Human geography & demography   Library & information sciences   Neurosciences & behavior   Regional & inter-regional studies   Social work & social policy   Sociology & social sciences   Social, industrial & organizational psychology   Theoretical & cognitive psychology   Treatment & clinical psychology   Multidisciplinary, general & others     Showing results 1401 to 1500 of 53124     10 11 12 13 14 15 16 17 18 19 20     Ten years of Martian nitric oxide nightglow observationsStiepen, Arnaud ; Gérard, Jean-Claude ; Gagné, Marie-Eve et alin Geophysical Research Letters (2015)Detailed reference viewed: 22 (4 ULg) Dark anti atoms can explain DAMAWallemacq, Quentin ; Cudell, Jean-René in Journal of Cosmology and Astroparticle Physics [= JCAP] (2015)We show that the existence of a sub-dominant form of dark matter, made of dark 'antiatoms' of a mass of 1 TeV and a size of 30 fm, can explain the results of direct detection experiments, with a positive ... [more ▼]We show that the existence of a sub-dominant form of dark matter, made of dark 'antiatoms' of a mass of 1 TeV and a size of 30 fm, can explain the results of direct detection experiments, with a positive signal in DAMA/NaI and DAMA/LIBRA and no signal in other experiments. The signal comes from the binding of the dark anti-atoms to thallium, a dopant in DAMA, and is not present for the constituent atoms of other experiments. The dark anti-atoms are made of two particles oppositely charged under a dark U(1) symmetry and can bind to terrestrial atoms because of a kinetic mixing between the photon and the massless dark photon, such that the dark particles acquire an electric milli-charge of ± 5.10(−)(4)e. This millicharge enables them to bind to high-Z atoms via radiative capture, after they thermalize in terrestrial matter through elastic collisions. [less ▲]Detailed reference viewed: 17 (2 ULg) Highly efficient, long life, reusable and robust photosynthetic hybrid core-shell beads for the sustainable production of high value compoundsDesmet, Jonathan; Meunier, Christophe; Danloy, Emeric et alin Journal of Colloid & Interface Science (2015), 448An efficient one-step process to synthesize highly porous (Ca-alginate–SiO2–polycation) shell: (Na-alginate– SiO2) core hybrid beads for cell encapsulation, yielding a reusable long-life ... [more ▼]An efficient one-step process to synthesize highly porous (Ca-alginate–SiO2–polycation) shell: (Na-alginate– SiO2) core hybrid beads for cell encapsulation, yielding a reusable long-life photosynthetically active material for a sustainable manufacture of high-value metabolites is presented. Bead formation is based on crosslinking of an alginate biopolymer and mineralisation of silicic acid in combination with a coacervation process between a polycation and the silica sol, forming a semi-permeable external membrane. The excellent mechanical strength and durability of the monodispersed beads and the control of their porosity and textural properties is achieved by tailoring the silica and alginate loading, polycation concentration and incubation time during coacervation. This process has led to the formation of a remarkably robust hybrid material that confers exceptional protection to live cells against sheer stresses and contamination in a diverse range of applications. Dunaliella tertiolecta encapsulated within this hybrid core–shell system display high photosynthetic activity over a long duration (>1 year). This sustainable biotechnology could find use in high value chemical harvests and biofuel cells to photosynthetic solar cells (energy transformation, electricity production, water splitting technologies). Furthermore the material can be engineered into various forms from spheres to variable thickness films, broadening its potential applications. 2015 Elsevier Inc. All rights reserved. [less ▲]Detailed reference viewed: 23 (2 ULg) Synthesis and anticancer activities of a novel class of mono- and di-metallic Pt(II)(salicylaldiminato)- (DMSO or Picolino)Cl complexesFaiz-Ur Rahman; Ali, Amjad ; Rong Guo et alin Dalton Transactions (2015)A series of novel Pt(II) complexes [cis- and trans-Pt(II)(salicylaldimine)(DMSO)Cl (C-1), trans-Pt(II)(salicylaldimine)( 4-picoline)Cl (C-2), Pt(II)(salicylaldimine)Cl (C-3), trans- and cis/trans-Pt2(II ... [more ▼]A series of novel Pt(II) complexes [cis- and trans-Pt(II)(salicylaldimine)(DMSO)Cl (C-1), trans-Pt(II)(salicylaldimine)( 4-picoline)Cl (C-2), Pt(II)(salicylaldimine)Cl (C-3), trans- and cis/trans-Pt2(II)(salicylaldimine) (DMSO)2Cl2 (C-4), trans-Pt2(II)(salicylaldimine)(4-picoline)2Cl2 (C-5) was synthesized and characterized. The structures of C-1-cis, C-1-trans and C-3 were determined using a single crystal X-ray analysis. This class of Pt(II) complexes has been studied for their in vitro cytotoxicity in multiple human cancer cell lines, including breast (MCF-7), liver (HepG2), lung (A549), colon (HCT116) and cervical (Hela) cancers. C-1- trans, C-2 and C-4-trans showed significant cytotoxicity to these cancer cells comparable to cisplatin. A time- and dose-dependent MTT assay revealed that these complexes can suppress cell viability and cell proliferation. Mechanistically these complexes induced pro-apoptotic gene expression such as BAX, PUMA and NOXA and thereby enhanced apoptosis. Moreover, PARP cleavage in a dose-dependent manner indicated their cytotoxic effect against cancer cells. Apoptosis of cancer cells occurred through apoptotic pathways as explained by the cytometry analysis. The DNA unwinding properties of these active Pt(II) complexes were studied by gel electrophoresis using pBR322 plasmid DNA as a target. Changes in the morphology of cancer cells were also observed upon the addition of C-1-trans, C-2 and C-4-trans. [less ▲]Detailed reference viewed: 12 (0 ULg) Methionine-derived Schiff base as selective fluorescent “turn-on”chemosensor for Zn2+in aqueous medium and its application in livingcells imagingFaiz-Ur-Rahman; Ali, Amjad ; Rong Guo et alin Sensors and Actuators B: Chemical (2015)tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN ... [more ▼]tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN/H2O (1:1) solution. In physiological pH (7.2 buffered) SMSB exhibited high selectivity and sen-sitivity toward Zn2+over the other selected metal ions. Upon the addition of Zn2+33 folds of emissionenhancement was observed in SMSB and limit of detection (CL) for Zn2+was found to be 5.0 × 10−7M. Thisbinding phenomenon was studied by1H NMR and HR-MS analysis. Mass spectrometry analysis revealedthat SMSB interacts with Zn2+and form a 1:1 complex, also confirmed by Job’s plot. This probe wascompletely retrieved by adding EDTANa2solution, exhibited a fluorescent quenching effect by removingZn2+from the sensor. SMSB was observed to have a good tolerance for fluorescence detection of Zn2+in pH range 6–10. Furthermore it is successfully investigated for living cells imaging using MCF-7 cells.Combine experimental results indicated SMSB to be a useful and powerful chemosensing probe for Zn2+in water as well as in living cells. [less ▲]Detailed reference viewed: 13 (0 ULg) In situ investigation of scCO2 assisted impregnation of drug into polymer by high pressure FTIR micro-spectroscopyChampeau, Mathilde ; Thomassin, Jean-Michel ; Jérôme, Christine et alin Analyst (2015), 140(3), 869-879An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers ... [more ▼]An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers or films, subjected to supercritical CO2. Thanks to this experimental set-up, key factors governing the impregnation process can be simultaneously followed such as the swelling of the polymeric matrix, the CO2 sorption, the kinetic of impregnation and the drug loading into the matrix. Moreover, the solute/polymer interactions and the speciation of the solute can be analyzed. We have monitored in situ the impregnation of aspirin and ketoprofen into PEO (Polyethylene Oxide) platelets at T=40°C and P=5; 10 and 15 MPa. The kinetic of impregnation of aspirin was quicker than the one of ketoprofen and the final drug loading was also higher in case of aspirin. Whereas the CO2 sorption and the PEO swelling remain constant when PEO is just subjected to CO2 under isobaric conditions, we noticed that both parameters can increase while the drug impregnates PEO. Coupling these results with DSC measurements, we underlined the plasticizing effect of the drug that also leads to decrease the crystallinity of PEO in situ thus favoring the sorption of CO2 molecules into the matrix and the swelling of the matrix. The plasticizing effect increases with the drug loading. Finally, the speciation of drug was investigated considering the shift of the carboxyl bands of the drugs. Both drugs were found to be mainly homogeneously dispersed into PEO. [less ▲]Detailed reference viewed: 53 (9 ULg) Revisiting the SN1987A gamma-ray limit on ultralight axion-like particlesPayez, Alexandre ; Evoli, Carmelo; Fischer, Tobias et alin Journal of Cosmology and Astroparticle Physics [= JCAP] (2015), 2015(02), 006We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and ... [more ▼]We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and eventually convert into gamma rays in the magnetic field of the Milky Way. The lack of a gamma-ray signal in the GRS instrument of the SMM satellite in coincidence with the observation of the neutrinos emitted from SN1987A therefore provides a strong bound on their coupling to photons. Due to the large uncertainty associated with the current bound, we revise this argument, based on state-of-the-art physical inputs both for the supernova models and for the Milky-Way magnetic field. Furthermore, we provide major amendments, such as the consistent treatment of nucleon-degeneracy effects and of the reduction of the nuclear masses in the hot and dense nuclear medium of the supernova. With these improvements, we obtain a new upper limit on the photon-ALP coupling: g_{a\gamma} < 5.3 x 10^{-12} GeV^{-1}, for m_a < 4.4 x 10^{-10} eV, and we also give its dependence at larger ALP masses. Moreover, we discuss how much the Fermi-LAT satellite experiment could improve this bound, should a close-enough supernova explode in the near future. [less ▲]Detailed reference viewed: 19 (14 ULg) Single Wavelength Coarse Phasing In Segmented TelescopesSimar, Juan Felipe ; Stockman, Yvan ; Surdej, Jean in Applied Optics (2015), 54Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because ... [more ▼]Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because of manufacturing limitations. For space telescopes, the primary mirrors are limited to less than 5 m due to fairing capacity. Segmented primary mirrors thus constitute an alternative solution to deal with the steadily increase of the primary mirror size. The optical path di erence between the individual segments must be close to zero (few nm) in order to be di raction limited. We propose in this paper a new inter-segment piston sensor based on coherence measurement of a star image. This sensor is intended to be used in the co-phasing system of future segmented mirrors. [less ▲]Detailed reference viewed: 84 (50 ULg) 18F-FPRGD2 PET/CT imaging of integrin αvβ3 in renal carcinomas: Correlation with histopathologyWITHOFS, Nadia ; SIGNOLLE, NICOLAS; SOMJA, Joan et alin Journal of Nuclear Medicine (The) (2015)Detailed reference viewed: 43 (8 ULg) Quaternary prevention, an answer of family doctors to overmedicalizationJamoulle, Marc in International Journal of Health Policy and Management (2015), 4((X)), 1-4In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying ... [more ▼]In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying to highlight the complexity and depth of the work of his colleagues and their contribution to the understanding of the organization and economy of healthcare. It addresses, in particular, the management of health elements throughout the ongoing relationship of the family doctor with his/her patients. It shows how the three dimensions of prevention, clearly included in the daily work, are complemented with the fourth dimension, quaternary prevention or prevention of medicine itself, whose understanding could help to control the economic and human costs of healthcare [less ▲]Detailed reference viewed: 415 (13 ULg) Challenges for imaging and therapy of musculoskeletal tumoursCOOK, GARY; HUSTINX, Roland in Clinical and Translational Imaging (2015)Detailed reference viewed: 31 (6 ULg) Contribution to the Macrophytic Typology of Belgian Reference WatercoursesGaloux, Daniel; Cherot, Frédéric; Rosillon, Francis et alin Advances in Botany (2015), Volume 2015, Article ID 651369The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment ... [more ▼]The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment basininWalloniaasasteptowardstheimplementationoftheEuropeanWaterFrameworkDirective.The50sitesstudiedarethe objectofaphysicochemicalandenvironmentalcharacterizationfollowedbyafloristicsurvey(phanerogams,mosses,liverworts, andmacroalgae).Sixclustersofwatercourseswiththeircharacteristicspeciesarehighlightedbytwo-wayclusteringandindicator species. The abundance of phanerogams in some watercourses of the Arden region is not only linked to light intensity but also dependsonthedegreeofslopeandthenatureofthegeologicalsubstrate [less ▲]Detailed reference viewed: 28 (3 ULg) Estimation of the Time Interval between the Administration of Heroin and the Sampling of Blood in Chronic InhalersDUBOIS, Nathalie ; HALLET, Claude ; SEIDEL, Laurence et alin Journal of Analytical Toxicology (2015)To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in ... [more ▼]To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in the study. Several plasma samples were collected during the detoxification procedure and analyzed for the heroin metabolites 6-acetylmorphine (6AM), morphine (MOR), morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G), according to a UHPLC/MSMS method. The general linear mixed model was applied to time-related concentrations and a pragmatic four-step delay estimation approach was proposed based on the simultaneous presence of metabolites in plasma. Validation of the model was carried out using the jackknife technique on the 11 patients, and on a group of 7 test patients. Quadratic equations were derived for all metabolites except 6AM. The interval delay estimation was 2–4 days when only M3G present in plasma, 1–2 days when M6G and M3G were both present, 0–1 day when MOR, M6G and M3G were present and <2 h for all metabolites present. The ‘jackknife’ correlation between declared and actual estimated delays was 0.90. The overall precision of the delay estimates was 8–9 h. The delay between last heroin consumption and blood sampling in chronic drug users can be satisfactorily predicted from plasma heroin metabolites. [less ▲]Detailed reference viewed: 47 (18 ULg) Differential Performance between Two Timber Species in Forest Logging Gaps and in Plantations in Central AfricaFayolle, Adeline ; Ouedraogo, Dakis-Yaoba ; Ligot, Gauthier et alin Forests (2015), 6(2), 380-394To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer ... [more ▼]To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer light demander Pericopsis elata (assamela, Fabaceae) in logging gaps and in plantations in highly degraded areas in south-eastern Cameroon. The survival and size of each seedling was regularly monitored in the silvicultural experiments. Differences in performance and allometry were tested between species in logging gaps and in plantations. The two species performance in logging gaps was significantly different from plantations and concurred with the expectations of the performance trade-off hypothesis but not with the expectations of species light requirements. The pioneer M. excelsa survived significantly better in logging gaps while the non-pioneer P. elata grew significantly faster in plantations. The high mortality and slow growth of M. excelsa in plantations is surprising for a pioneer species but could be explained by herbivory (attacks from a gall-making psyllid). Identifying high-value native timber species (i) with good performance in plantations such as P. elata is of importance to restore degraded areas; and (ii) with good performance in logging gaps such as M. excelsa is of importance to maintain timber resources and biodiversity in production forests. [less ▲]Detailed reference viewed: 20 (5 ULg) Magnetic shielding of an inhomogenous magnetic field source by a bulk superconducting tubeHogan, Kevin ; Fagnard, Jean-François ; Wera, Laurent et alin Superconductor Science and Technology (2015), 28(3), 035011Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic ... [more ▼]Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic shields have mainly been studied in a homogenous magnetic field, considering only immunity problems, i.e. when the field is applied outside the tube and the inner field should ideally be zero. In this paper, we aim to investigate experimentally and numerically the magnetic response of a high-Tc bulk superconducting hollow cylinder at 77 K in an emission problem, i.e. when subjected to the non-uniform magnetic field generated by a source coil placed inside the tube. A bespoke 3-D mapping system coupled with a 3-axis Hall probe is used to measure the magnetic flux density distribution outside the superconducting magnetic shield. A finite element model is developed to understand how the magnetic field penetrates into the superconductor and how the induced superconducting shielding currents flow inside the shield in the case where the emitting coil is placed coaxially inside the tube. The finite element modelling is found to be in excellent agreement with the experimental data. Results show that a concentration of the magnetic flux lines occurs between the emitting coil and the superconducting screen. This effect is observed both with the modelling and the experiment. In the case of a long tube, we show that the main features of the field penetration in the superconducting walls can be reproduced with a simple analytical 1D model. This model is used to estimate the maximum flux density of the emitting coil that can be shielded by the superconductor. [less ▲]Detailed reference viewed: 63 (37 ULg) The non-convex shape of (234) Barbara, the first BarbarianTanga, Paolo; Carry, B.; Colas, F. et alin Monthly Notices of the Royal Astronomical Society (2015)Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits ... [more ▼]Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits several peculiar features, most notably its polarimetric behavior. In recent years other objects sharing the same property (collectively known as ”Barbarians”) have been discovered. Interferometric observations in the mid-infrared with the ESO VLTI suggested that (234) Barbara might have a bi-lobated shape or even a large companion satellite. We use a large set of 57 optical lightcurves acquired between 1979 and 2014, together with the timings of two stellar occultations in 2009, to determine the rotation period, spin-vector coordinates, and 3-D shape of (234) Barbara, using two different shape reconstruction algorithms. By using the lightcurves combined to the results obtained from stellar occultations, we are able to show that the shape of (234) Barbara exhibits large concave areas. Possible links of the shape to the polarimetric properties and the object evolution are discussed. We also show that VLTI data can be modeled without the presence of a satellite [less ▲]Detailed reference viewed: 27 (9 ULg) TRAPPIST monitoring of comet C/2012 F6 (Lemmon)Opitom, Cyrielle ; Jehin, Emmanuel ; Manfroid, Jean et alin Astronomy and Astrophysics (2015), 574We report the results of the long-term narrowband photometry and imaging monitoring of comet C/2012 F6 (Lemmon) with the robotic TRAPPIST telescope (La Silla Observatory). Observations covered 52 nights ... [more ▼]We report the results of the long-term narrowband photometry and imaging monitoring of comet C/2012 F6 (Lemmon) with the robotic TRAPPIST telescope (La Silla Observatory). Observations covered 52 nights pre- and post-perihelion between December 11, 2012, and June 11, 2013 (perihelion: 24 March, 2013). We followed the evolution of the OH, NH, CN, C[SUB]3[/SUB], and C[SUB]2[/SUB] production rates computed with the Haser model as well as the evolution of the A(θ)fρ parameter as a proxy for the dust production. All five gas species display similar slopes for the heliocentric dependence. An asymmetry about perihelion is observed, the rate of brightening being steeper than the rate of fading. The chemical composition of the comet's coma changes slightly along the orbit: the relative abundance of C[SUB]2[/SUB] to CN increases with the heliocentric distance (r) below -1.4 au and decreases with r beyond 1.4 au while the C[SUB]3[/SUB]-to-CN ratio is constant during our observations. The behavior of the dust is different from that of the gas, the slope of the heliocentric dependence becoming steeper in early February, correlated to a change in the visual lightcurve slope. However, the dust color does not vary during the observations. The application of several enhancement techniques on the images revealed structures in the CN, C[SUB]3[/SUB], and C[SUB]2[/SUB] images. These features imply the existence of one or several active zone(s) on the comet nucleus. The shape of the structures is similar in these three filters and changes from a roughly hourglass shape in December and January to a corkscrew shape in February and March. The structures in the continuum filters (sampling the dust) are not correlated to those observed for the gas. During several full nights in February, we observed changes in the CN and C[SUB]2[/SUB] structures that repeated periodically because of the nucleus rotation, our derived rotational period being of 9.52 ± 0.05 h. Full Tables 2, 4, 6 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/574/A38 [less ▲]Detailed reference viewed: 30 (9 ULg) Economics of a decision-support system for managing the main fungal diseases of winter wheat in the Grand-Duchy of LuxembourgEl Jarroudi, Moussa ; Kouadio, Louis; Beyer, Marco et alin Field Crops Research (2015), 172(2), 32-41We evaluated the cost effectiveness of a decision-support system (DSS) developed for assessing in real time the risk of progression of the main fungal diseases (i.e., Septoria leaf blotch, powdery mildew ... [more ▼]We evaluated the cost effectiveness of a decision-support system (DSS) developed for assessing in real time the risk of progression of the main fungal diseases (i.e., Septoria leaf blotch, powdery mildew, leaf rusts and Fusarium head blight) of winter wheat in the Grand-Duchy of Luxembourg (GDL). The study was conducted in replicated field experiments located in four agricultural locations (representative of the main agro-ecological regions of the country) over a 10-year period (2003-2012). Three fungicide spray strategies were compared: a single DSS-based system and two commonly used spray practices in the GDL, a double- (2T)- and a triple- spray (3T) spray treatment; there was also a non-treated control. In years with a high disease pressure, the DSS-based recommendation resulted in protection of the three upper leaves comparable to that achieved with the 2T and 3T treatments, with significant grain yield increases (P > 0.05) compared to the control (a 4 to 42% increase, depending on the site and year). Overall, the financial gain in treated plots compared with the control ranged from 3 to 16% at the study sites. Furthermore, in seasons when dry weather conditions precluded epidemic development, no the DSS-basedDSS recommended no fungicide spray was recommended, reducing use of fungicide, and thus saving the cost of the product. The gain in yield for the 2T and 3T plots (compared with control) did not necessarily result in a financial gain during the duration of the experiment. This study demonstrates the potential advantages and profitability of using a DSS -based approach for disease management. [less ▲]Detailed reference viewed: 26 (3 ULg) New spectroscopic and polarimetric observations of the A0 supergiant HD 92207Hubrig, S.; Kholtygin, A. F.; Schöller, M. et alin Astronomische Nachrichten (2015), 336Our recent search for the presence of a magnetic field in the bright early A-type supergiant HD 92207 using FORS 2 in spectropolarimetric mode revealed the presence of a longitudinal magnetic field of the ... [more ▼]Our recent search for the presence of a magnetic field in the bright early A-type supergiant HD 92207 using FORS 2 in spectropolarimetric mode revealed the presence of a longitudinal magnetic field of the order of a few hundred Gauss. However, the definite confirmation of the magnetic nature of this object remained pending due to the detection of short-term spectral variability probably affecting the position of line profiles in left- and right-hand polarized spectra. We present new magnetic field measurements of HD 92207 obtained on three different epochs in 2013 and 2014 using FORS 2 in spectropolarimetric mode. A 3σ detection of the mean longitudinal magnetic field using the entire spectrum, _all=104±34 G, was achieved in observations obtained in 2014 January. At this epoch, the position of the spectral lines appeared stable. Our analysis of spectral line shapes recorded in opposite circularly polarized light, i.e. in light with opposite sense of rotation, reveals that line profiles in the light polarized in a certain direction appear slightly split. The mechanism causing such a behaviour in the circularly polarized light is currently unknown. Trying to settle the issue of short-term variability, we searched for changes in the spectral line profiles on a time scale of 8-10 min using HARPS polarimetric spectra and on a time scale of 3-4 min using time series obtained with the CORALIE spectrograph. No significant variability was detected on these time scales during the epochs studied. Based on observations collected with the CORALIE echelle spectrograph mounted on the 1.2-m Swiss telescope at La Silla Observatory, data obtained at the European Southern Observatory (ESO Prg. 092.D-0209(A), and data obtained from the ESO Science Archive Facility under request MSCHOELLER 102067). [less ▲]Detailed reference viewed: 24 (0 ULg) The summer 2012 Greenland heat wave: in situ and remote sensing observations of water vapour isotopic composition during an atmospheric river event†Bonne, JL; Steen-Larsen, HC; Risi, C. et alin Journal of Geophysical Research. Atmospheres (2015)During July 7-12, 2012, extreme moist and warm conditions occurred over Greenland, leading to widespread surface melt. To investigate the physical processes during the atmospheric moisture transport of ... [more ▼]During July 7-12, 2012, extreme moist and warm conditions occurred over Greenland, leading to widespread surface melt. To investigate the physical processes during the atmospheric moisture transport of this event, we study the water vapour isotopic composition using surface in situ observations in Bermuda Island, South Greenland coast (Ivittuut) and Northwest Greenland ice sheet (NEEM), as well as remote sensing observations (IASI instrument on-board MetOp-A), depicting propagation of similar surface and mid-tropospheric humidity and δD signals. Simulations using Lagrangian moisture source diagnostic and water tagging in a regional model showed that Greenland was affected by an atmospheric river transporting moisture from the western subtropical North Atlantic Ocean, which is coherent with observations of snow pit impurities deposited at NEEM. At Ivittuut, surface air temperature, humidity and δD increases are observed. At NEEM, similar temperature increase is associated with a large and long-lasting ~100 δD enrichment and ~15 deuterium excess decrease, thereby reaching Ivittuut level. We assess the simulation of this event in two isotope-enabled atmospheric general circulation models (LMDz-iso and ECHAM5-wiso). LMDz-iso correctly captures the timing of propagation for this event identified in IASI data but depict too gradual variations when compared to surface data. Both models reproduce the surface meteorological and isotopic values during the event but underestimate the background deuterium excess at NEEM. Cloud liquid water content parametrization in LMDz-iso poorly impacts the vapour isotopic composition. Our data demonstrate that during this atmospheric river event the deuterium excess signal is conserved from the moisture source to Northwest Greenland. [less ▲]Detailed reference viewed: 36 (1 ULg) A comparison between visual estimates and image analysis measurements to determine Septoria leaf blotch severity in winter wheatEl Jarroudi, Moussa ; Kouadio, Louis; Mackels, Christophe et alin Plant Pathology (2015)Methods to estimate disease severity vary in accuracy, reliability, ease of use and cost. Severity of Septoria leaf blotch (SLB, caused by Zymoseptoria graminicola) was estimated by four raters and by ... [more ▼]Methods to estimate disease severity vary in accuracy, reliability, ease of use and cost. Severity of Septoria leaf blotch (SLB, caused by Zymoseptoria graminicola) was estimated by four raters and by image analysis (assumed actual values) on individual leaves of winter wheat in order to explore accuracy and reliability of estimates, and to ascertain whether there were any general characteristics of error. Specifically, (i) we determined the accuracy and reliability of visual assessments of SLB over the full range of severity from 0 to 100%, and we investigated (ii) whether certain 10% ranges in actual disease severity between 0 and 100% were more prone to estimation error compared with others, and (iii) whether leaf position affected accuracy within those ranges. Lin's concordance correlation analysis of all severities (0 to 100%) demonstrated that all raters had estimates close to the actual values (agreement: ρc = 0.92-0.99). However, agreement between actual SLB severities and estimates by raters was less good when compared over short 10% subdivisions within the 0-100% range (ρc = -0.12 to 0.99). Despite common rater imprecision at estimating low and high SLB severities, individual raters differed considerably in their accuracy over the short 10% subdivisions. There was no effect of leaf position on accuracy or precision of severity estimate on separate leaves (L1-L3). Pursuing efforts in understanding error in disease estimation should aid in improving the accuracy of assessments, making visual estimates of disease severity more useful for research and applied purposes. [less ▲]Detailed reference viewed: 13 (0 ULg) A Review of Pharmaceutical Extrusion: Critical Process Parameters and Scaling-upThiry, Justine ; Krier, Fabrice ; Evrard, Brigitte in International Journal of Pharmaceutics (2015), 479(1), 227-240Hot melt extrusion has been a widely used process in the pharmaceutical area for three decades. In this field, it is important to optimize the formulation in order to meet specific requirements. However ... [more ▼]Hot melt extrusion has been a widely used process in the pharmaceutical area for three decades. In this field, it is important to optimize the formulation in order to meet specific requirements. However, the process parameters of the extruder should be as much investigated as the formulation since they have a major impact on the final product characteristics. Moreover, a design space should be defined in order to obtain the expected product within the defined limits. This gives some freedom to operate as long as the processing parameters stay within the limits of the design space. Those limits can be investigated by varying randomly the process parameters but it is recommended to use design of experiments. An examination of the literature is reported in this review to summarize the impact of the variation of the process parameters on the final product properties. Indeed, the homogeneity of the mixing, the state of the drug (crystalline or amorphous), the dissolution rate, the residence time, can be influenced by variations in the process parameters. In particular, the impact of the following process parameters: temperature, screw design, screw speed and feeding, on the final product, has been reviewed. [less ▲]Detailed reference viewed: 62 (27 ULg) The Well-aligned Orbit of Wasp-84b: Evidence for Disk Migration of a Hot JupiterAnderson, D. R.; Triaud, A. H. M. J.; Turner, O. D. et alin Astrophysical Journal Letters (2015), 800We report the sky-projected orbital obliquity (spin-orbit angle) of WASP-84 b, a 0.69{{M}[SUB]Jup[/SUB]} planet in an 8.52 day orbit around a G9V/K0V star, to be λ = -0.3 ± 1.7°. We obtain a true ... [more ▼]We report the sky-projected orbital obliquity (spin-orbit angle) of WASP-84 b, a 0.69{{M}[SUB]Jup[/SUB]} planet in an 8.52 day orbit around a G9V/K0V star, to be λ = -0.3 ± 1.7°. We obtain a true obliquity of ψ = 17.3 ± 7.7° from a measurement of the inclination of the stellar spin axis with respect to the sky plane. Due to the young age and the weak tidal forcing of the system, we suggest that the orbit of WASP-84b is unlikely to have both realigned and circularized from the misaligned and/or eccentric orbit likely to have arisen from high-eccentricity migration. Therefore we conclude that the planet probably migrated via interaction with the protoplanetary disk. This would make it the first “hot Jupiter” (P\lt 10 d) to have been shown to have migrated via this pathway. Further, we argue that the distribution of obliquities for planets orbiting cool stars (T[SUB]eff[/SUB] < 6250 K) suggests that high-eccentricity migration is an important pathway for the formation of short-orbit, giant planets. Based on observations made with the HARPS-North spectrograph on the 3.6 m Telescopio Nazionale Galileo under OPTICON program 2013 B/069, the HARPS spectrograph on the ESO 3.6 m telescope under program 090.C-0540, and the RISE photometer on the 2.0 m Liverpool Telescope under programs PL12B13 and PL14A11. The photometric time-series and radial-velocity data used in this work are available at the CDS. [less ▲]Detailed reference viewed: 14 (1 ULg) Self-assembly of a triblock terpolymer mediated by hydrogen-bonded complexesGuerlain, Claire; Piogé, Sandie; Detrembleur, Christophe et alin Journal of Polymer Science. Part A, Polymer Chemistry (2015), 53(3), 459-467A poly(methyl methacrylate)-block-poly(4-vinylpyridine)-block-polystyrene (PMMA-b-P4VP-b-PS) triblock terpolymer is synthesized by ATRP to study its self-assembly with PAA in organic solvents. The self ... [more ▼]A poly(methyl methacrylate)-block-poly(4-vinylpyridine)-block-polystyrene (PMMA-b-P4VP-b-PS) triblock terpolymer is synthesized by ATRP to study its self-assembly with PAA in organic solvents. The self-assembly behavior of this system is compared with the one of a mixture of two diblocks, namely polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) and poly(methyl methacrylate)-block-poly(methacrylic acid) (PMMA-b-PMAA). For both systems, formation of hydrogen-bonded complexes between the P4VP and PMAA or PAA blocks occurs. These complexes become insoluble in the solvent used and micelles with a P4VP/P(M)AA complexes core surrounded by PS and PMMA coronal chains are obtained in both cases. These micelles are analyzed by DLS and TEM. Spherical micelles are formed for both systems but the hydrodynamic radii obtained for the two types of micelles are different. Indeed, the micelles formed by the PMMA-b-P4VP-b-PS + PAA system are smaller than those observed for the PS-b-P4VP + PMMA-b-PMAA system. Finally, the effect of the molar ratio of the P4VP/PMAA complexing blocks is investigated. [less ▲]Detailed reference viewed: 19 (1 ULg) Signes et jouabilité : l’interface comme outil de ludicisationBarnabé, Fanny in Interfaces Numériques (2015), 4(1), As shown by the recent works on the subject (Rao, 2008 ; Simonnot, 2008 ; all papers presented at the symposium Game and playability in the digital age), researchers now seem to agree on the fact that the ... [more ▼]As shown by the recent works on the subject (Rao, 2008 ; Simonnot, 2008 ; all papers presented at the symposium Game and playability in the digital age), researchers now seem to agree on the fact that the digital has an intrinsic playability (it is “ludogenic” according to Vial, 2012) and that this property is not uninvolved with the current spread of the “gamification” or “ludification” (Genvo, 2011) phenomenons. Following these considerations, this paper aims to examine a specific angle of this privileged relationship between digital and game, namely the fundamental role played by the interfaces (both graphical and physical). We will try to demonstrate through various examples the deeply playable nature (I.e suitable to set off a playful attitude) of the different kinds of interface, but also to examine its causes: is there a structural basis that could explain this affinity with the play? With this aim in mind, theories of game (playful attitude) will be intersected with interface theories in order to demonstrate the existence of many similarities. The hypothesis that guides this work is that this transitional device’s playability owes more to its semiotic nature than to its belonging to digital. Indeed, as a system of signs, the interface has two characteristics that make it fit to generate a playful attitude in the user: the metaphoric distance and the increase of possible actions. [less ▲]Detailed reference viewed: 49 (2 ULg) Les états spatio-temporels d'existence et de présenceHallot, Pierre ; Stewart, Kathleen; Billen, Roland in Revue Internationale de Géomatique = International Journal of Geomatics and Spatial Analysis (2015), 25(2), 173-196This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an ... [more ▼]This paper addresses a new approach to formalize the spatiotemporal relationships between geographical objects that do not exist or that are not present at the time of the analysis. We propose first an analysis of the spatiotemporal states of existence and presence for a geographical object. Then, we combine the spatiotemporal states to define a comprehensive set of life and motion configuration. The proposed model serves as formal basis to perform spatiotemporal queries by retrieving selected patterns in the life and motion configurations. The research is applied to the organization of a scientific conference, in doing so we are able to define the relationships that exist between an event located in space and time and mobiles objects evolving within the space, i.e. the conference participants. [less ▲]Detailed reference viewed: 79 (23 ULg) A one-step short-time synthesis of Ag@SiO2 core-shell nanoparticlesLismont, Marjorie ; Pàez Martinez, Carlos ; Dreesen, Laurent in Journal of Colloid & Interface Science (2015)A performance of shell-thickness precise control in silver-silica coating core-shell nanoparticles is presented. 60 nm sized citrate-stabilized silver nanoparticles are directly silica coated using a ... [more ▼]A performance of shell-thickness precise control in silver-silica coating core-shell nanoparticles is presented. 60 nm sized citrate-stabilized silver nanoparticles are directly silica coated using a modified Stöber process. Tetraethyl orthosilicate is used as a silica precursor and ammonium hydroxide as catalyst in an alcoholic solvent to promote the seeded silica growth. By simply varying the synthesis reaction time from 4 to 60 minutes, the silica shell thickness is increased from 5.1 nm to 76.4 nm. This well-controlled synthesis is then transposed to 40, 80 and 100 nm sized silver cores in order to show the independence of the silica shell growth on the nanoparticle core size. Optical properties, i.e. localized surface plasmon resonance, of the produced silver-silica core-shell are also investigated. [less ▲]Detailed reference viewed: 50 (6 ULg) Solucion de la doble imposicion internacional en las relationes entre america latina y el mundo exterionMALHERBE, Jacques; Richelle, Isabelle ; TRAVERSA, Edoardoin Revista del Instituto peruana de Derecho Tributario (2015), 58(1), 7-58Proposition d'un modèle sud-américain pour la convention préventive de la double imposition OCDEDetailed reference viewed: 11 (0 ULg) Wasabi, de Alan Pauls. Una lectura alegórica en clave autoficcional.Vanden Berghe, Kristine in Pasavento. Revista de Estudios Hispánicos. (2015)Se lee Wasabi (Alan Pauls, 1994, 2005) como una novela neofantástica emparentada con La metamorfosis de Kafka y ciertos cuentos de Cortázar. Asimismo, se procede a una lectura de la novela en clave ... [more ▼]Se lee Wasabi (Alan Pauls, 1994, 2005) como una novela neofantástica emparentada con La metamorfosis de Kafka y ciertos cuentos de Cortázar. Asimismo, se procede a una lectura de la novela en clave alegórica, atendiendo a una serie de metáforas (quiste, narcolepsias, wasabi) que aluden a las relaciones entre literatura y vida. En este sentido, se aborda el texto como una alegoría primero de la autoficción y luego de la creación literaria en general. A esta lectura alegórica la apoyan la recurrencia de la cifra siete en la novela así como la relación intertitular que esta tiene con Fils, novela autoficcional que Serge Doubrovsky escribiera en 1977. [less ▲]Detailed reference viewed: 48 (3 ULg) Bacteria may enhance species association in an ant-aphid mutualistic relationshipFischer, Christophe ; Lognay, Georges ; Detrain, Claire et alin Chemoecology (2015)The mutualistic relationships between certain ant and aphid species are well known, the primary benefits being protection for the aphids and carbohydrate-rich honeydew for the ants. Questions remain ... [more ▼]The mutualistic relationships between certain ant and aphid species are well known, the primary benefits being protection for the aphids and carbohydrate-rich honeydew for the ants. Questions remain, however, as to the exact semiochemical factors that establish and maintain such relationships. In this study we used a series of treatments and associated controls placed at the end of a two-way olfactometer to determine the degree of attractiveness of a complete plant-aphid-honeydew system as well as individual components of that system. Both the olfactometer branch selected by the black garden ant (Lasius niger), and the linear speed with which ants moved through the device, were measured. Study results showed that ants were attracted not just to the complete plant system and the honeydew itself, but also to the microbial flora in the absence of plant or honeydew, and specifically to a bacterium from the black bean aphid (Aphis fabae) honeydew, Staphylococcus xylosus. This bacterium produces a blend of semiochemicals that attract the ant scouts. This information suggests the presence of a naturally-occurring, reliable biotic cue for detection of potential aphid partners. This would have to be confirmed in natural conditions by further field experiments. Rather than being opportunistic species that coincidentally colonize a sugar-rich environment, microorganisms living in aphid honeydew may be able to alter emissions of volatile organic compounds (VOCs), thus significantly mediating partner attraction. A bacterial involvement in this mutualistic relationship could alter the manner in which these and similar relationships are viewed and evaluated. Future studies into mutualism stability and function among macroscopic partners will likely need to transition from a two-partner perspective to a multiple-partner perspective, and consider the microbial component, with the potential for one or more taxa making significant contributions to the relationship [less ▲]Detailed reference viewed: 27 (5 ULg) Total Error-Based Validation Including the Experimental Design-Based Robustness Evaluation of a Stability-Indicating Method for the Simultaneous Quantification of Hydrochlorothiazide and Valsartan in Tablet FormulationsELKARBANE, M; AMOOD AL-KAMARANY, M; BOUCHAFRA, H et alin Acta Chromatographica (2015), 27(2), 1-20A gradient reversed phase high-performance liquid chromatography (RPHPLC) method with ultraviolet (UV) detection to analyze hydrochlorothiazide (HCT) and valsartan (VS) simultaneously in a tablet ... [more ▼]A gradient reversed phase high-performance liquid chromatography (RPHPLC) method with ultraviolet (UV) detection to analyze hydrochlorothiazide (HCT) and valsartan (VS) simultaneously in a tablet formulation during forced degradation studies was developed. This method was validated using a novel approach, namely, the accuracy profile or total errors approach. The robustness of the method was evaluated using a Plackett–Burman design for eight factors. The algorithm of Dong was applied to determine the significant factor effects. The validation results showed that the method is precise (RSD: 1.14% for HCT and 0.43% for VS) and accurate (mean recovery: 99.90% for HCT and 99.98% for VS). On the other hand, the results of the robustness study showed that the type of column was the important factor which affects a number of responses, namely, the asymmetry factor (AF), retention time (RT), and resolution (RS). However, the assay results were not affected; therefore, the method can be considered robust. Finally, the method was applied to study the stability of HCT and VS under forced conditions. Significant results were obtained with basic hydrolysis, oxidation, and thermal stress, while the accelerated and acidic conditions did not affect the stability of HCT or VS. [less ▲]Detailed reference viewed: 56 (5 ULg) Exploring new dimensions in cadaveric decomposition odour analysisStefanuto, Pierre-Hugues ; Perrault, Katelynn; Lloyd, Rebecca et alin Analytical Methods (2015), 7This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound ... [more ▼]This study demonstrates the first documented use of comprehensive two-dimensional gas chromatography – high-resolution time-of-flight mass spectrometry (GC×GC-HRTOFMS) for volatile organic compound analysis in the forensic sciences. High-resolution mass spectral data provided higher confidence in analyte identification. GC×GC-HRTOFMS will be valuable for future studies of decomposition odour and other complex volatile matrices. [less ▲]Detailed reference viewed: 38 (8 ULg) BLUES ALL DAY LONG- The Jimmy Rogers story - compte renduSacré, Robert in ABS Magazine (2015), (45 Février 2015), 15Biographie de Jimmy Rogers par Wayne Everett GoinsDetailed reference viewed: 16 (0 ULg) Le dosage de la vitamine D: considérations pré-analytiques et analytiquesLE GOFF, Caroline ; Souberbielle, Jean-Claude; Delvin, Edgard et alin Annales de Biologie Clinique (2015), 73(1), 79-92The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being ... [more ▼]The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being unfortunately not fully harmonized, yield different results. Liquid chromatography coupled to tandem mass spectrometry has more recently been introduced. This approach allows the distinction between the two forms of 25-hydroxyvitamin D and to measure other metabolites. This approach also requires harmonization to curtail the differences between the different analytical methods. To meet this requirement, the American national institutes of health (NIH), the CDC (Center for disease control and prevention) in Atlanta, the NIST (National institute of standards and technology) and the vitamin D Reference laboratory of Ghent University have pooled their expertise to develop a standardization program. This article reviews the main elements and the difficulties of the automated and semi-automated methods for 25-hydroxyvitamin D, from sample preparation to the analytical phase, as well as those related to mass spectrometry. It also addresses the issues related to the clinical decision thresholds and the possibility of measurements in different biological liquids. [less ▲]Detailed reference viewed: 26 (9 ULg) Contribution à l’étude des caractéristiques du cycle oestral chez la brebis et les caractéristiques spermatiques chez le bélier de race Koundoum, au NigerHamadou, Issa ; Moula, Nassim ; MANI, Mamman et alin Revue de Médecine de Toulouse (2015), 166RÉSUMÉ L’étude a été conduite pour déterminer les caractéristiques du cycle oestral de la brebis et les caractéristiques spermatiques du bélier de la race à laine Koundoum du Niger. Seize brebis et huit ... [more ▼]RÉSUMÉ L’étude a été conduite pour déterminer les caractéristiques du cycle oestral de la brebis et les caractéristiques spermatiques du bélier de la race à laine Koundoum du Niger. Seize brebis et huit béliers Koundoum ont été utilisés pour cette étude. Les brebis ont été soumises à une observation biquotidienne de leur comportement sexuel en vue de détecter les oestrus, à l’aide de béliers boute-en-train. Les échantillons de sperme ont été recueillis à l’aide d’un vagin artificiel chez les béliers pendant les périodes d’oestrus des brebis. La motilité du sperme a été déterminée à l’aide d’un microscope et sa concentration à l’aide d’un spectrophotomètre. Sur les 16 brebis, 13 ont manifesté au moins une fois des comportements d’oestrus ayant une durée moyenne de 37,8±5,8 heures avec une durée de cycle oestral de 18,1±1,1 jours. La collecte de semence a été réalisée sur 4 béliers sur les 8 inclus dans le protocole. Les éjaculats collectés ont présenté un volume moyen de 1,03±0,3 ml, une motilité de 3,4, et une concentration de 1322±544 millions/ ml. La connaissance de la durée du cycle et de l’oestrus est un élément de base pour la maîtrise de la fonction sexuelle des brebis. La difficulté de collecte de la semence de béliers Koundoum devra être prise en compte dans les plans de conservation par cryogénisation de paillettes. Les informations obtenues à travers cette étude sont une base permettant de poser les premiers jalons du programme de conservation et d’amélioration de cette race. [less ▲]Detailed reference viewed: 19 (6 ULg) De- and Re-Institutionalizing Technology Assessment in Contemporary Knowledge-Based EconomiesDelvenne, Pierre ; Charlier, Nathan ; Rosskamp, Benedikt et alin Technikfolgenabschätzung - Theorie und Praxis (2015), 24(1), 130This article illuminates the potential role of technology assessment (TA) in knowl- edge-driven science, technology and inno- vation (STI) regimes by providing a compar- ative review of Flemish and ... [more ▼]This article illuminates the potential role of technology assessment (TA) in knowl- edge-driven science, technology and inno- vation (STI) regimes by providing a compar- ative review of Flemish and Walloon TA. It draws critical attention to the ways in which TA actors and institutes in Flanders and Wal- lonia position themselves, or are positioned, in relation to dominant innovation policies and large-scale political transformations, notably the convergence of STI around the knowledge-based economy (KBE) and the regionalization of STI policy in Belgium. The article’s findings shed light on the Flemish government’s recent decision to close its parliamentary TA institute and the institution- al expansion of TA in Wallonia and elsewhere in Europe. It argues that TA has politics, as TA in Flanders and Wallonia aligns with the advent of strategic science and is also affil- iated to specific political parties. As these considerations run counter to the dominant representation of TA as a neutral governance tool that serves the needs of all STI decision makers, they draw into question the viability and utility of TA within contemporary KBEs. [less ▲]Detailed reference viewed: 43 (7 ULg) Chylothorax et pseudochylothorax: contraste a partir de deux observations.Berg, J.; GUIOT, Julien ; HEINEN, Vincent et alin Revue Médicale de Liège (2015), 70(2), 73-7We report two cases of lipidic pleural effusion: an arthritis-associated pseudochylothorax and a chylous pleural effusion in a HIV seropositive patient. The incidence of lipidic pleural effusions is low ... [more ▼]We report two cases of lipidic pleural effusion: an arthritis-associated pseudochylothorax and a chylous pleural effusion in a HIV seropositive patient. The incidence of lipidic pleural effusions is low, especially for pseudochylothorax. We review their clinical characteristics and management. [less ▲]Detailed reference viewed: 40 (1 ULg) La thermoplastie bronchique dans le traitement de l'asthme sévère de l'adulte.Chanez, P.; Boulet, L.-P.; Brillet, P.-Y. et alin Revue des maladies respiratoires (2015), 32Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since ... [more ▼]Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based treatment, the evaluation procedure of risks and benefits is different that for pharmaceutical products; safety aspects, regulatory requirements, study design and the assessment of the magnitude of effects may all be different. The mechanism of action and optimal patient selection need to be assessed further in rigorous clinical and scientific studies. This technique is in harmony with the development of personalised medicine in the 21st century. It should be developed further in response to the numerous challenges and needs not yet met in the management of severe asthma. [less ▲]Detailed reference viewed: 49 (14 ULg) Place de la vitamine D native en dialyseDELANAYE, Pierre ; BOUQUEGNEAU, Antoine ; KRZESINSKI, Jean-Marie et alin Néphrologie & Thérapeutique (2015), 11(1), 5-15Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first ... [more ▼]Chronic kidney disease is frequent and usually responsible of mineral and bone disorder. These abnormalities lead to increased morbidity and mortality. To become active, native vitamin D needs a first hydroxylation in the liver, and a second one in the kidney. Next to its action on bone metabolism, vitamin D also possesses pleiotropic actions on cardiovascular, immune and neurological systems as well as antineoplastic activities. End-stage renal disease (ESRD) is also associated with a decrease in vitamin D activity by mechanisms including the increase of plasma phosphate concentration, secretion of FGF- 23 and decrease in 1a-hydroxylase activity. The prevalence of 25 hydroxy-vitamin D deficiency depends on the chosen cut-off value to define this lack. Currently it is well established that a patient has to be substituted when 25 hydroxy-vitamin D level is under 30 ng/mL. The use and monitoring of 1.25 hydroxy-vitamin D is still not recommended in routine practice. The goals of vitamin D treatment in case of ESRD are to substitute the deficiency and to prevent or treat hyperparathyroidism. Interest of native vitamin D in first intention is now well demonstrated. This review article describes the vitamin D metabolism and physiology and also the treatment for vitamin D deficiency in ESRD population. [less ▲]Detailed reference viewed: 18 (8 ULg) Evaluation of Water Resources Quality in Sabodala Gold Mining Region and Its Surrounding Area (Senegal)Mall, Ibrahima; Diaw, Moctar; Dieng, Ndeye Maguette et alin Journal of Water Resource and Protection (2015), 7(3), 247-263Geochemical and Geostatistical tools were used to assess: 1) the chemical quality and, geochemical processes in crystalline rock aquifers in Sabodala (Eastern Senegal) and its surroundings and 2) the ... [more ▼]Geochemical and Geostatistical tools were used to assess: 1) the chemical quality and, geochemical processes in crystalline rock aquifers in Sabodala (Eastern Senegal) and its surroundings and 2) the impact of mining activities on their quality. A total of 26 water samples collected at boreholes, dug wells and stream, were analyzed to determine major and trace elements concentration focused on elements that represent more threats on human health. Boxplots define chemical characteristics of water for each aquifer formation compared to surface waters. Geostatistical analysis show two sources of water mineralization with regard to major elements: a first natural source characterized by Ca-Mg-HCO3 water type from boreholes and unpolluted surface water and a second group characterized by polluted water by nitrates with Na-NO3-Cl type mainly observed in upper weathered aquifers. However, considering trace element, geostatistical analysis showed three water groups: water with very low trace element concentrations encountered in boreholes and unpolluted surface waters, and waters with relatively high trace element concentrations such as Al observed in areas affected by gold mining activities and finally, polluted waters by Ni, Co, Mn and Cr observed at Sabodala. Results show that in eastern Senegal well waters are vulnerable and often affected by pollution. [less ▲]Detailed reference viewed: 33 (5 ULg) Effect of iron nanoparticles synthesized by a sol-gel process on Rhodococcus erythropolis T902.1 for biphenyl degradationWannoussa, Wissal ; Masy, Thibaut ; Lambert, Stéphanie et alin Journal of Water Resource and Protection (2015), 7Nanoparticles (NPS) are considered as a new generation of compounds to improve environmental remediation and biological processes. The aim of this study is to investigate the effect of iron NPS ... [more ▼]Nanoparticles (NPS) are considered as a new generation of compounds to improve environmental remediation and biological processes. The aim of this study is to investigate the effect of iron NPS encapsulated in porous silica (SiO2) on the biphenyl biodegradation by Rhodococcus erythropolis T902.1 (RT902.1). The iron NPS (major iron oxide FexOy form) were dispersed in the porosity of a SiO2 support synthesized by sol-gel process. These Fe/SiO2 NPS offer a stimulating effect on the biodegradation rate of biphenyl, an organic pollutant that is very stable and water-insoluble. This positive impact of NPS on the microbial biodegradation was found to be dependent on the NPS concentration ranging from 10−6 M to 10−4 M. After 18 days of incubation the cultures containing NPS at a concentration of 10−4 M of iron improved RT902.1 growth and degraded 35% more biphenyl than those without NPS (positive control) or with the sole SiO2 particles. Though the microorganism could not interact directly with the insoluble iron NPS, the results show that about 10% and 35% of the initial 10−4 M iron NPS encapsulated in the SiO2 matrix would be incorporated inside or adsorbed on the cell surface respectively and 35% would be released in the supernatant. These results suggest that RT902.1 would produce siderophore-like molecules to attract iron from the porous silica matrix. [less ▲]Detailed reference viewed: 154 (92 ULg) Littérature et sémiotique: histoire et épistémologieProvenzano, François ; Bertrand, Jean-Pierre ; Stienon, Valérie in Signata. Annales des Sémiotiques = Annals of Semiotics (2015), 5(2014), 384La question des liens entre sémiotique et littérature amène à poser un regard rétrospectif sur une période qui paraît aujourd’hui révolue. L’émergence de la sémiotique comme discipline institutionnalisée ... [more ▼]La question des liens entre sémiotique et littérature amène à poser un regard rétrospectif sur une période qui paraît aujourd’hui révolue. L’émergence de la sémiotique comme discipline institutionnalisée est en effet contemporaine d’un profond changement de paradigme dans les approches du texte littéraire. Au cours de la décennie 1960, la rencontre entre sémiotique et littérature produit, en un temps très bref, un nombre considérable de concepts et d’instruments d’analyse, qui vont de la théorie du dialogisme et de la polyphonie à la sémanalyse en passant par la narratologie et la sémantique structurale. L'objectif de ce dossier est de saisir cette rencontre dans la perspective d’une histoire des idées, en éclairant ce qui, dans la conjoncture des années 1960, a pu favoriser la convergence, avant de la rendre caduque ou obsolète. Une place est également réservée aux témoignages pour laisser entendre, dans un souci d'historicisation, la voix d'acteurs importants de ces années sémio-littéraires: Philippe Hamon, le groupe Mu, Marc Angenot [less ▲]Detailed reference viewed: 58 (4 ULg) Nouveau traitement contre le carcinome basocellulaire avancéNIKKELS, Arjen in Mediaplanet (2015)Chaque année, entre 17 000 et 18 000 nouveaux cas du carcinome basocellulaire sont diagnostiqués en BelgiqueDetailed reference viewed: 18 (0 ULg) Représentations et expérience des pères « primipares » de l’allaitement maternel : lien avec la durée de l’allaitementNoirhomme-Renard, Florence ; Michèle, Close; Gosset, Christiane in Journal de Pédiatrie et de Puériculture (2015), 28(1), 7-15ntroduction. — This study aim to investigate fathers experiences and representations in regard to breastfeeding. Methods. — Two groups of fathers were recruited in the year following the birth of their ... [more ▼]ntroduction. — This study aim to investigate fathers experiences and representations in regard to breastfeeding. Methods. — Two groups of fathers were recruited in the year following the birth of their child: a group whose child was breastfed less than three months (n = 16), and the other whose child was breastfed more than 6months (n=17). They were interviewed by semi-structured interviews and completed a questionnaire of attitudes toward child feeding (IIFAS). Results. — Although the representation that had fathers of breastfeeding during pregnancy dif- fered somewhat between the two groups, medical and social factors are primarily associated with a short AM: medical complications in the mother or the child, social vulnerabilities, early breastfeeding difficulties. The involvement of health professionals has been mentioned by many fathers when breastfeeding difficulties, but it has, in most cases, led to the failure of AM in time. Increased fathers take place in the triad, sometimes modulated by their partner, and their emo- tional involvement and practice in breastfeeding are associated with long AM. Fathers whose baby was breastfed for more than 6 months have a score more in favor of breastfeeding on the scale IIFAS. Conclusion. — The inclusion of fathers in the comprehensive model of the determinants of breastfeeding provides further insight to the factors already identified. [less ▲]Detailed reference viewed: 52 (9 ULg) Maurice Duverger (1917-2014) (in memoriam)Bouhon, Frédéric in Journal des Tribunaux (2015)Detailed reference viewed: 7 (0 ULg) How to Assess Data Availability, Accessibility and Format for Risk Analysis?Humblet, Marie-France ; Vandeputte, Sébastien; Mignot, Clémence et alin Transboundary and Emerging Diseases (2015), doi: 10.1111/tbed.12328Risk assessments are mostly carried out based on available data, which do not reflect all data theoretically required by experts to answer them. This study aimed at developing a methodology to assess data ... [more ▼]Risk assessments are mostly carried out based on available data, which do not reflect all data theoretically required by experts to answer them. This study aimed at developing a methodology to assess data availability, accessibility and format, based on a scoring system and focusing on two diseases: Venezuelan equine encephalomyelitis (VEE), still exotic to Europe, and alveolar echinococcosis, caused by Echinococcus multilocularis (EM), endemic in several Member States (MSs). After reviewing 36 opinions of the EFSA-AHAW Panel on risk assessment of animal health questions, a generic list of needed data was elaborated. The methodology consisted, first, in implementing a direct and an indirect survey to collect the data needed for both case studies: the direct survey consisted in a questionnaire sent to contact points of three European MSs (Belgium, France and the Netherlands), and the organization of a workshop gathering experts on both diseases. The indirect survey, focusing on the three MSs involved in the direct survey plus Spain, relied on web searches. Secondly, a scoring system with reference to data availability, accessibility and format was elaborated, to, finally, compare both diseases and data between MSs. The accessibility of data was generally related to their availability. Web searches resulted in more data available for VEE compared to EM, despite its current exotic status in the European Union. Hypertext markup language and portable document files were the main formats of available data. Data availability, accessibility and format should be improved for research scientists/assessors. The format of data plays a key role in the feasibility and rapidness of data management and analysis, through a prompt compilation, combination and aggregation in working databases. Harmonization of data collection process is encouraged, according to standardized procedures, to provide useful and reliable data, both at the national and the international levels for both animal and human health; it would allow assessing data gaps through comparative studies. The present methodology is a good way of assessing the relevance of data for risk assessment, as it allows integrating the uncertainty linked to the quality of data used. Such an approach could be described as transparent and traceable and should be performed systematically. [less ▲]Detailed reference viewed: 15 (1 ULg) Zooarchaeology of the layers from Dorochivtsy III (Ukraine)Demay, Laëtitia ; Patou-Mathis, Marylène; Koulakovska, Larissain Quaternary International (2015)Palaeolithic archaeological sites of the Western Ukraine are clustered along the Prut and Dniester Rivers. Different sites provided data enabling reconstruction of the paleoenvironment, chronology and ... [more ▼]Palaeolithic archaeological sites of the Western Ukraine are clustered along the Prut and Dniester Rivers. Different sites provided data enabling reconstruction of the paleoenvironment, chronology and cultures of human group during the Upper Paleolithic (notably Molodova V). During the second part of the Pleniglacial, between 23 000 and 20 000 years BP, palaeoclimatic variations took place. The intensification of cold and arid conditions is liable to force human groups to adapt to a changing environment. Little is known about this period, with only a few assemblages. Ongoing excavations continue to provide new data. The archaeological site of Dorochivtsy III has an important sequence stratigraphy with several archaeological layers. Among the seven Upper Palaeolithic layers, layers 6, 5, 4 and 3 testify to activities of a human group during the Upper Pleniglacial. We studied the faunal assemblages applying zooarchaeological methods, identifying mammoth (Mammuthus primigenius), reindeer (Rangifer tarandus), horse (Equus sp.) and fox (Alopex lagopus/Vulpes vulpes). The Gravettian layers 3, 4, 5 have anthropogenic clues in connection with subsistence activities oriented on reindeer, then horses, and finally fox. Concerning mammoths, we cannot define the modes of acquisition and use. These occupations have been interpreted as recurrent hunting occupations linked to procurement of local flint and lithic production for butchering activities. Layer 6 dated to 22 330 ± 100 BP is remarkable because of previously unseen practises. The lithic assemblage combined with bone industry and engraved tusk is a novel set of cultural elements in this area, called ancient Epigravettian. This layer testifies to the diversity of human activities during the Upper Pleniglacial and to the particular status of mammoth ivory as an artistic medium. Palynological data and taphonomic observations on bones indicate the persistence of relatively moist conditions during some periods, which could favour the movement of human groups. Although little is known about the Upper Pleniglacial period, Dorochivtsy III testifies to the continuity of a large exploitation of the territory of the Dniester valley. [less ▲]Detailed reference viewed: 14 (0 ULg) Jean-Michel Mouton, Dominique Sourdel, Janine Sourdel-Thomine: Mariage et séparation à Damas au Moyen Âge: un corpus de 62 documents juridiques inédits entre 337/948 et 698/1299. (Documents relatifs à l'histoire des croisades. vol. XXI) 326 pp. Paris: Académie des Inscriptions et Belles-Lettres, 2013. €40. ISBN 978-2-87754-296-8.Bauden, Frédéric in Bulletin of the School of Oriental and African Studies (2015), 78(1), 182-184Detailed reference viewed: 45 (2 ULg) Standardisation of milk mid-infrared spectra from a European dairy networkGrelet, Clément ; Fernandez Pierna, Juan Antonio; Dardenne, Pierre et alin Journal of Dairy Science (2015), 98http://www.journalofdairyscience.org/article/S0022-0302(15)00091-0/abstractDetailed reference viewed: 24 (6 ULg) Increased tree-growth synchronization of beech (Fagus sylvatica L.) in response to climate change in northwestern EuropeLatte, Nicolas ; Lebourgeois, François; Claessens, Hugues in Dendrochronologia (2015), 33To better understand how the radial growth of beech (Fagus sylvatica L.) high forests has responded to climate change, we selected 12 sites (137 trees) with optimal growing conditions along a W − E ... [more ▼]To better understand how the radial growth of beech (Fagus sylvatica L.) high forests has responded to climate change, we selected 12 sites (137 trees) with optimal growing conditions along a W − E altitudinal gradient (67–590 m) in Belgium. We evaluated temporal changes in growth response to climate by using pointer year analysis, moving mean sensitivities (1860–2011), and moving bootstrapped correlation coefficients (1952–2011). The strongest driving climatic variables were identified by using the partial least squares method. The common patterns of growth trends, pointer years, and mean sensitivities among sites provided evidences for the impact of environmental changes operating at a regional scale. The results of growth–climate analysis indicated that these changes were strongly influenced by the climatic conditions of the previous year. The climate sensitivity of beech increased progressively in response to more frequent and intense heat waves and warming-related droughts, especially during recent decades, leading to remarkable inter-site synchronization. The changes were much more pronounced for sites located in lowlands (<300 m). The differences in growth responses along the altitudinal gradient and the consequences of warming for beech growth and physiology are discussed. [less ▲]Detailed reference viewed: 43 (16 ULg) Racisme, Islam et langage codéJamin, Jérôme in Politique, revue de débats (2015), 88Detailed reference viewed: 24 (4 ULg) Nonlinear generalization of Den Hartog׳s equal-peak methodHabib, Giuseppe ; Detroux, Thibaut ; Viguié, Régis et alin Mechanical Systems & Signal Processing (2015), 52-53This study addresses the mitigation of a nonlinear resonance of a mechanical system. In view of the narrow bandwidth of the classical linear tuned vibration absorber, a nonlinear absorber, termed the ... [more ▼]This study addresses the mitigation of a nonlinear resonance of a mechanical system. In view of the narrow bandwidth of the classical linear tuned vibration absorber, a nonlinear absorber, termed the nonlinear tuned vibration absorber (NLTVA), is introduced in this paper. An unconventional aspect of the NLTVA is that the mathematical form of its restoring force is tailored according to the nonlinear restoring force of the primary system. The NLTVA parameters are then determined using a nonlinear generalization of Den Hartog׳s equal-peak method. The mitigation of the resonant vibrations of a Duffing oscillator is considered to illustrate the proposed developments. [less ▲]Detailed reference viewed: 49 (14 ULg) Analysis versus synthesis for trending gas-path measurement time seriesBorguet, Sébastien ; Léonard, Olivier ; Dewallef, Pierre in Journal of Engineering for Gas Turbines & Power (2015), 137Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear ... [more ▼]Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear filters such as the EWMA filter are traditionally used for noise removal. Unfortunately, these low-pass filters distort trend shifts indicative of faults, which increases the detection delay. The present paper investigates two new approaches to nonlinear filtering of time series. On the one hand, the synthesis approach reconstructs the signal as a combination of elementary signals chosen from a predefined library. On the other hand, the analysis approach imposes a constraint on the shape of the signal (e.g., piecewise constant). Both approaches incorporate prior information about the signal in a different way, but they lead to trend filters that are very capable at noise removal while preserving at the same time sharp edges in the signal. This is highlighted through the comparison with a classical linear filter on a batch of synthetic data representative of typical engine fault profiles. [less ▲]Detailed reference viewed: 23 (1 ULg) On modular decompositions of system signaturesMarichal, Jean-Luc; Mathonet, Pierre in Journal of Multivariate Analysis (2015), 134Considering a semicoherent system made up of $n$ components having i.i.d. continuous lifetimes, Samaniego defined its structural signature as the $n$-tuple whose $k$-th coordinate is the probability that ... [more ▼]Considering a semicoherent system made up of $n$ components having i.i.d. continuous lifetimes, Samaniego defined its structural signature as the $n$-tuple whose $k$-th coordinate is the probability that the $k$-th component failure causes the system to fail. This $n$-tuple, which depends only on the structure of the system and not on the distribution of the component lifetimes, is a very useful tool in the theoretical analysis of coherent systems. It was shown in two independent recent papers how the structural signature of a system partitioned into two disjoint modules can be computed from the signatures of these modules. In this work we consider the general case of a system partitioned into an arbitrary number of disjoint modules organized in an arbitrary way and we provide a general formula for the signature of the system in terms of the signatures of the modules. The concept of signature was recently extended to the general case of semicoherent systems whose components may have dependent lifetimes. The same definition for the $n$-tuple gives rise to the probability signature, which may depend on both the structure of the system and the probability distribution of the component lifetimes. In this general setting, we show how under a natural condition on the distribution of the lifetimes, the probability signature of the system can be expressed in terms of the probability signatures of the modules. We finally discuss a few situations where this condition holds in the non-i.i.d. and nonexchangeable cases and provide some applications of the main results. [less ▲]Detailed reference viewed: 24 (0 ULg) Projet-pilote pour un habitat en adéquation avec les attentes des habitants des zones dites HP : histoire d'un processus et de projetsDawance, Sophie in Les Echos du logement (2015), 1En Wallonie, quelques 10.000 personnes vivent de manière permanente dans des infrastructures de loisirs, souvent dans une grande précarité matérielle mais aussi une insécurité juridique et physique. Cette ... [more ▼]En Wallonie, quelques 10.000 personnes vivent de manière permanente dans des infrastructures de loisirs, souvent dans une grande précarité matérielle mais aussi une insécurité juridique et physique. Cette situation a amené le Gouvernement wallon à adopter un plan d'action transversal appelé le Plan HP . L’une des mesure de ce Plan prévoit de « préparer et lancer un appel à projets sous forme de concours à destination des sociétés privées et bureaux d’architecture portant sur la conception d’un projet … spécifique, original, économique (moins de 100.000 euros par logement hors terrain) et en adéquation avec les attentes des publics visés ». Cette mesure s’appuie sur le constat relayé par les acteurs de terrain que le logement public « classique » n’est souvent pas adapté aux besoins de ces habitants et ignore, voire anéantit, les stratégies pourtant parfois riches et inventives, qu’ils ont développées pour habiter. Le concours prévu par le Plan HP vise donc la conception de logements économiques à la construction et à l’usage répondant aux besoins spécifiques des habitants permanents des infrastructures de loisirs. [less ▲]Detailed reference viewed: 21 (4 ULg) RAC avec discordance gradient/surfaceHENRI, Christine; PIERARD, Luc in Réalités Cardiologiques (2015), 307Detailed reference viewed: 20 (0 ULg) Effects of low dose endosulfan exposure on brain neurotransmitter levels in the African clawed frog Xenopus laevisPreud'Homme, Valérie; Milla, Sylvain; Gillardin, Virginie et alin Chemosphere (2015), 120(2), 357-364Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of ... [more ▼]Understanding the impact of pesticides in amphibians is of growing concern to assess the causes of their decline. Among pesticides, endosulfan belongs to one of the potential sources of danger because of its wide use and known effects, particularly neurotoxic, on a variety of organisms. However, the effect of endosulfan was not yet evaluated on amphibians at levels encompassing simultaneously brain neurotransmitters and behavioural endpoints. In this context, tadpoles of the African clawed frog Xenopus laevis were submitted to four treatments during 27 d: one control, one ethanol control, and two low environmental concentrations of endosulfan (0.1 and 1 μg L−1). Endosulfan induced a significant increase of brain serotonin level at both concentrations and a significant increase of brain dopamine and GABA levels at the lower exposure but acetylcholinesterase activity was not modified by the treatment. The gene coding for the GABA transporter 1 was up-regulated in endosulfan contaminated tadpoles while the expression of other genes coding for the neurotransmitter receptors or for the enzymes involved in their metabolic pathways was not significantly modified by endosulfan exposure. Endosulfan also affected foraging, and locomotion in links with the results of the physiological assays, but no effects were seen on growth. These results show that low environmental concentrations of endosulfan can induce adverse responses in X. laevis tadpoles. At a broader perspective, this suggests that more research using and linking multiple markers should be used to understand the complex mode of action of pollutants. [less ▲]Detailed reference viewed: 110 (31 ULg) La cardiomyopathie du cirrhotique : un bref aperçuMARCHETTA, Stella ; DELWAIDE, Jean ; LANCELLOTTI, Patrizio in Revue Médicale de Liège (2015), 2Detailed reference viewed: 53 (3 ULg) Systematic qualitative review of randomised trials conducted in nonsmall cell lung cancer with a noninferiority or equivalence designPaesmans, Marianne; Grigoriu, Bogdan; Ocak, Sebahat et alin European Respiratory Journal (2015), 45(2), 511-524The use of noninferiority randomised trials for patients with advanced non-small cell lung cancer has emerged during the past 10–15 years but has raised some issues related to their justification and ... [more ▼]The use of noninferiority randomised trials for patients with advanced non-small cell lung cancer has emerged during the past 10–15 years but has raised some issues related to their justification and methodology. The present systematic review aimed to assess trial characteristics and methodological aspects. All randomised clinical trials with a hypothesis of noninferiority/equivalence, published in English, were identified. Several readers extracted a priori defined methodological information. A qualitative analysis was then performed. We identified 20 randomised clinical trials (three phase II and 17 phase III), 11 of them being conducted in strong collaboration with industry. We highlighted some deficiencies in the reports like the lack of justification for both the noninferiority assumption and the definition of the noninferiority margin, as well as inconsistencies between the results and the authors’ conclusions. CONSORT guidelines were better followed for general items than for specific items (p<0.001). Improvement in the reporting of the meth"odology of noninferiority/equivalence trials is needed to avoid misleading interpretation and to allow readers to be fully aware of the assumptions underlying the trial designs. They should be restricted to limited specific situations with a strong justification why a noninferiority hypothesis is acceptable. [less ▲]Detailed reference viewed: 17 (2 ULg) Stochastic modelling of reservoir sedimentation in a semi-arid watershedAdam, Nicolas; Erpicum, Sébastien ; Archambeau, Pierre et alin Water Resources Management (2015), 29(3), 785-800Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real ... [more ▼]Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real case of the reservoir of Sidi Yacoub in the north of Algeria. First, a dynamic model of the reservoir was set up and used to estimate past water and sediment inflows (period 1990-2010) based on data recorded by the dam operator and measurements at a gauging station located downstream of the reservoir. Second, in a stochastic framework using the statistical characteristics of inflow and outflow discharges, a projection of future sedimentation was performed until 2030, assuming stationarity of the statistical distributions. Third, the model was used to investigate the influence of possible climate change and to quantify the positive effects of soil conservation measures upstream. [less ▲]Detailed reference viewed: 104 (28 ULg) Lecture de Olivesi Stéphane, L'expérience esthétique. Une archéologie des arts et de la communicationVandeninden, Elise in Communication (2015), 33/1Detailed reference viewed: 15 (4 ULg) Management and systemic treatment of clear cell metastatic renal cell carcinoma: BSMO expert panel recommendationsEl Ali, Z; Van Brummelen, D; Wolter, P et alin Belgian Journal of Medical Oncology [=BJMO] (2015), 9(1), Detailed reference viewed: 31 (0 ULg) Oncological and surgical outcome after oncoplastic breast surgeryNIZET, Jean-Luc ; MAWEJA, Sylvie ; LAKOSI, Ferenc et alin Acta Chirurgica Belgica (2015), 115BACKGROUND: Oncoplastic surgery combines breast-conserving treatment and plastic surgery techniques. The aim of the study was to identify breast and tumor-related characteristics that contribute to the ... [more ▼]BACKGROUND: Oncoplastic surgery combines breast-conserving treatment and plastic surgery techniques. The aim of the study was to identify breast and tumor-related characteristics that contribute to the rate of complications and recurrence. METHODS: This retrospective study included 72 patients with a median follow-up of 32 months. For each patient, a comprehensive set of data was collected, including epidemiology, tumor characteristics, preoperative information, detailed pathology reports, radiotherapy treatment and type of surgical technique. The rate of complications, recurrence and survival were studied. RESULTS: Complete tumor removal was performed with clear margins in all patients but in 25 of them margins were less than 2 mm. One patient had local recurrence and another developed distant metastases. The study showed that the size of the margin was not predictive of recurrence as long as not positive; the greater the resection volume, the larger the excision margin. The resection size was the only factor influencing complications and no specific tumor-related factor significantly increased the complication rate. Surgical complications did not delay the initiation of chemotherapy and radiotherapy. CONCLUSIONS: This is the first oncoplastic study where both tumor and breast characteristics were analyzed using the most recent criteria of the literature. Oncoplastic surgery can be considered as oncologically safe. The resection size was the sole significant risk factor for postoperative complications. Complications after oncoplastic breast surgery did not differ neoadjuvant therapy. Long-term event-free survival was excellent (96% at 7 years). [less ▲]Detailed reference viewed: 26 (7 ULg) Clinical pharmacology of antifungal agents to overcome drug resistance in pediatric patientsSTERGIOPOULOU, Theodouli ; Walsh, Thomas J.in Expert opinion on pharmacotherapy (2015), 16(2), 213-26INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological ... [more ▼]INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERED: This paper reviews the mechanisms of resistance of different classes of antifungal agents and the current understanding of pediatric antifungal pharmacology for overcoming antifungal resistance in children based on laboratory and clinical studies in the English literature. The therapeutic choices against fungal pathogens with intrinsic or acquired resistance are further reviewed. EXPERT OPINION: There is a paucity of data in the pediatric population regarding the epidemiology of the resistant organisms to different antifungal agents. It is also unknown if there are more prevalent molecular mechanisms that promote antifungal resistance. Selection and dosages of the most effective antifungal agent for overcoming the antifungal resistance is crucial. However, there are limited studies guiding the optimal dosage and duration of treatment for management of emergent antifungal resistance. Further studies are warranted to elucidate the optimal pharmacology of the current antifungal agents against resistant organisms and to advance the development of new antifungal agents. [less ▲]Detailed reference viewed: 30 (3 ULg) Withdrawal time for sulfamethoxazole and trimethoprim following treatment of striped catfish (Pangasianodon hypophthalmus) and hybrid red tilapia (Oreochromis mossambicus × Oreochromis niloticus)Tran Minh, Phu; Scippo, Marie-Louise ; Nguyen Thanh, Phuong et alin Aquaculture (2015), 437Detailed reference viewed: 19 (2 ULg) Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studiesShepherd, Nicholas; Gamsjaeger, Roland; Vandevenne, Marylène et alin Tetrahedron (2015), 71(5), 813-819Detailed reference viewed: 1 (0 ULg) A revised DR Congo mining code could lead to a decrease in Chinese investment in the countryWintgens, Sophie in Africa at LSE (2015)As China shows indications of being willing to fall in line with international standards on procuring conflict minerals, this article examines the strategic issues facing China as DR Congo seeks to revise ... [more ▼]As China shows indications of being willing to fall in line with international standards on procuring conflict minerals, this article examines the strategic issues facing China as DR Congo seeks to revise its mining code. [less ▲]Detailed reference viewed: 45 (5 ULg) Impact of roughness and circularity-defect on bridge cables stabilityBenidir, Adel; Flamand, Olivier; Gaillet, Laurent et alin Journal of Wind Engineering & Industrial Aerodynamics (2015), 137The stay cables on cable-stayed bridges have been the subject of considerable research in order to understand the origins of the dry galloping phenomenon. Surface irregularity is one of the last ... [more ▼]The stay cables on cable-stayed bridges have been the subject of considerable research in order to understand the origins of the dry galloping phenomenon. Surface irregularity is one of the last parameters that have not been thoroughly examined. This paper focuses on static wind tunnel tests on original High Density Polyethylene cable covers in a range of Reynolds numbers from the sub-critical regime to the critical, corresponding to values ranging from Re = 9.6x104 to Re = 3.3x105. The experiment consists in testing cable covers of various diameters in order to investigate the effect of surface irregularity (roughness and circularity defect) on the mechanism of dry galloping excitation. Previous studies reported that dry galloping is caused by the appearance of a negative pressure bubble on one side of the circular cylinder at the critical Reynolds number range, leading to a rapid drop in the drag coefficient and the appearance of a non-negligible lift force. The results of the present investigation demonstrate that there is a clear correlation between the single bubble pressure pattern and the circularity defect along the tube. They further show that surface roughness has little effect on the location of the bubble. The paper also treats the spatial and temporal correlation of the instantaneous pressure pattern along the tube with respect to the circularity defect. [less ▲]Detailed reference viewed: 46 (1 ULg) Epidémiologie de la lithiase urinaire sur base d'une analyse morpho-constitutionnelleCastiglione, Vincent ; JOURET, François ; Bruyère, Olivier et alin Néphrologie & Thérapeutique (2015), 11Urolithiasis is a common condition, with a prevalence of 10% and a male/female ratio above 1 according to large national series. Various types of urinary stones have been described upon their mineral ... [more ▼]Urolithiasis is a common condition, with a prevalence of 10% and a male/female ratio above 1 according to large national series. Various types of urinary stones have been described upon their mineral content and/or their morphology. Hence, a combined morpho-constitutional (M-C) classification has been proposed. In order to detail the prevalence of urolithiasis in general and of each M-C type in particular upon age and gender in Belgium, we retrospectively studied the database of a reference center for urolithiasis analysis. Between 2010 and 2013, 2195 stones were characterized. We excluded 45 nonbiological stones and 281 stones, which originated from outside the study zone. Among 1869 stones,1293 (69.2%) affected men. Prevalence peak of urolithiasis was observed between 50–60 years of age in both genders. The M-C analysis was available for 1854 stones (99.2%): multiple morphological types were concomitantly identified in 49.3%. In the whole population, the main mineral constituent was whewellite (54.4%), mainly organized as type Ia (94%). Weddellite was found in 19.8%, with an equal distribution between types IIa and IIb. Uric acid was the 3rd most frequent constituent in man, with a similar distribution between IIIa and IIIb. Phosphate was uncommon in man (8.2%), but frequent in woman (26.6%) with a type IVa1 organization. Prevalence of M-C types changes with aging, i.e. decrease of weddellite and increase of whewellite and uric acid in both genders. This retrospective analysis of a single-center database of urinary stones helps characterize the M-C epidemiology of urolithiasis in Belgium. [less ▲]Detailed reference viewed: 82 (36 ULg) Erzählen im Zeitalter des Internets Daniel Kehlmanns "Ruhm" und Daniel Glattauers "Gut gegen Nordwind"Dupont, Bruno in Germanica (2015), 55(2014), 189-207Detailed reference viewed: 81 (8 ULg) B fields in OB stars (BOB): on the detection of weak magnetic fields in the two early B-type stars beta CMa and epsilon CMaFossati, L.; Castro, N.; Morel, Thierry et alin Astronomy and Astrophysics (2015), 574Within the context of the "B fields in OB stars (BOB)" collaboration, we used the HARPSpol spectropolarimeter to observe the early B-type stars beta CMa (HD44743; B1 II/III) and epsilon CMa (HD52089; B1.5 ... [more ▼]Within the context of the "B fields in OB stars (BOB)" collaboration, we used the HARPSpol spectropolarimeter to observe the early B-type stars beta CMa (HD44743; B1 II/III) and epsilon CMa (HD52089; B1.5 II). For both stars, we consistently detected the signature of a weak (<30 G in absolute value) longitudinal magnetic field. We determined the physical parameters of both stars and characterise their X-ray spectrum. For beta CMa, our mode identification analysis led to determining a rotation period of 13.6+/-1.2 days and of an inclination angle of the rotation axis of 57.6+/-1.7 degrees, with respect to the line of sight. On the basis of these measurements and assuming a dipolar field geometry, we derived a best fitting obliquity of ~22 degrees and a dipolar magnetic field strength (Bd) of ~100 G (60 Aims: Our aim is to measure some of the properties (inner radius, brightness profile, shape) of the inner regions of circumstellar disk surrounding southern T Tauri stars.