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See detailLa garantie des biens de consommation : quelques questions non résolues par la loi
Englebert, Marine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2015), (9-10), 421-426

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See detailAnalyse critique des traitements conservateurs classiques des tendinopathies
KAUX, Jean-François ULg; Croisier, Jean-Louis ULg; Forthomme, Bénédicte ULg et al

in Revue Médicale de Liège (2015), 70(9), 456-460

Les thérapeutiques «passives» classiques (anti-inflammatoires, infiltrations de corticoïdes…) des tendinopathies, utilisées de manière relativement empirique, réduisent la douleur et l’inflammation, sans ... [more ▼]

Les thérapeutiques «passives» classiques (anti-inflammatoires, infiltrations de corticoïdes…) des tendinopathies, utilisées de manière relativement empirique, réduisent la douleur et l’inflammation, sans modifier fondamentalement la structure du tendon, expliquant leur vocable et caractère «passif». La rééducation excentrique a été appliquée aux tendinopathies chroniques, non seulement de par l’échec des traitements classiques, mais aussi en raison d’une meilleure compréhension physiopathologique des tendinopathies. Diverses études soulignent l’efficacité de la rééducation excentrique qui, après 20-30 séances, entraîne la guérison et surtout prévient le risque de chronicité. Les ondes de choc, modifiant la structure tendineuse, permettraient une guérison à plus long terme. [less ▲]

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See detailPourquoi travailler systématiquement avec des exponentielles de base e ?
Bair, Jacques ULg; Henry, Valérie ULg; Justens, Daniel

in Tangente (2015), 166

Le nombre e est omniprésent en mathématiques: on le retrouve en analyse, en trigonométrie, en calcul des probabilités. Il apparaît dans nombre d'applications en finance, en physique, en actuariat. Nous ... [more ▼]

Le nombre e est omniprésent en mathématiques: on le retrouve en analyse, en trigonométrie, en calcul des probabilités. Il apparaît dans nombre d'applications en finance, en physique, en actuariat. Nous montrons dans cet article ce qui fait de ce nombre une base incontournable. [less ▲]

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See detailImplementation of a damage evolution law for dual-phase steels in Gurson-type models
Balan, Tudor; Lemoine, Xavier; Maire, eric et al

in Materials and Design (2015), (88), 1213-1222

This paper is a contribution to the phenomenological modeling of damage evolution in DP steels in the framework of Gurson’s approach. It is based on recent results of X-ray tomography in-situ tensile ... [more ▼]

This paper is a contribution to the phenomenological modeling of damage evolution in DP steels in the framework of Gurson’s approach. It is based on recent results of X-ray tomography in-situ tensile tests and subsequent one-dimensional metallurgical void nucleation models proposed in [C. Landron et al., Scripta Materialia 63 (2010) 973—976]. A macroscopic void nucleation law for DP steels is proposed, covering a wide range of stress triaxialities. The respective effects of nucleation, growth and coalescence are clearly separated. Validations with respect to experimental porosity measurements were performed for several monotonic loading cases and for two loading sequences involving large strains and strain-path changes. [less ▲]

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See detailPHYSICAL-CHEMICAL PROPERTIES OF MILK FAT GLOBULE MEMBRANE AT DIFFERENT STAGES OF ISOLATION
Malik, Priyanka ULg; Danthine, Sabine ULg; Paul, Aman ULg et al

in Scientific Bulletin. Series F. Biotechnologies (2015), XIX

Fat globules in milk are present in form of emulsion stabilized by milk fat globule membrane (MFGM) which originates in mammary gland. Buttermilk which is rich source of MFGM finds application as an ... [more ▼]

Fat globules in milk are present in form of emulsion stabilized by milk fat globule membrane (MFGM) which originates in mammary gland. Buttermilk which is rich source of MFGM finds application as an ingredient in dairy and food industry (emulsions, infant formulas & low fat products) for its emulsifying and stabilizing properties which are associated to polar lipids. Phospholipids & some proteins have also shown some medicinal properties. So, MFGM received much attention in recent years due to its health-beneficial & technological properties. This work has been carried out with the objective to characterize MFGM at different stages of extraction. MFGM fractions were isolated from fresh cream and collected at different steps during processing to study its physical-chemical characterization. The fractions were characterized for their chemical composition to have an idea at which stage which components are isolated. The sample were also characterized for their surface properties which included study of mechanical properties of monolayer using Langmuir film balance, surface tension and zeta potential. Physical-chemical studies of fractions suggest that each fraction of MFGM have different chemical composition and surface properties which could be of interest for use in different food products depending on the requirement. The choice of these fractions could be done for their use as food additive/ingredient in food industry depending on the application. It may even have an extended application in pharmaceutical industry. [less ▲]

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See detailDonor Age in Liver Transplantation: Donation after Circulatory Death.
DETRY, Olivier ULg

in Journal of the American College of Surgeons (2015), 221(3), 779

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See detailAssimilation of sea surface temperature, sea ice concentration and sea ice drift in a model of the Southern Ocean
Barth, Alexander ULg; Canter, Martin ULg; Van Schaeybroeck, Bert et al

in Ocean Modelling (2015), 93

Current ocean models have relatively large errors and biases in the Southern Ocean. The aim of this study is to provide a reanalysis from 1985 to 2006 assimilating sea surface temperature, sea ice ... [more ▼]

Current ocean models have relatively large errors and biases in the Southern Ocean. The aim of this study is to provide a reanalysis from 1985 to 2006 assimilating sea surface temperature, sea ice concentration and sea ice drift. In the following it is also shown how surface winds in the Southern Ocean can be improved using sea ice drift estimated from infrared radiometers. Such satellite observations are available since the late seventies and have the potential to improve the wind forcing before more direct measurements of winds over the ocean are available using scatterometry in the late nineties. The model results are compared to the assimilated data and to independent measurements (the World Ocean Database 2009 and the mean dynamic topography based on observations). The overall improvement of the assimilation is quantified, in particular the impact of the assimilation on the representation of the polar front is discussed. Finally a method to identify model errors in the Antarctic sea ice area is proposed based on Model Output Statistics techniques using a series of potential predictors. This approach provides new directions for model improvements. [less ▲]

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See detailLa responsabilité du prêteur dans l'octroi du crédit
Englebert, Marine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2015), (9-10), 468-471

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See detailNetBenchmark: a bioconductor package for reproducible benchmarks of gene regulatory network inference
Bellot, Pau; Olsen, Catharina; Salembier, Philippe et al

in BMC Bioinformatics (2015)

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See detailThe human NANOS3 gene contributes to lung tumour invasion by inducing epithelial-mesenchymal transition
Grelet, S; Andries, V; Polette, M et al

in Journal of Pathology (The) (2015), 237(1), 25-37

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See detailLeve de rechtskeuze!
Wautelet, Patrick ULg

in Tijdschrift voor Estate planning (2015), (3), 258-262

Cette contribution tente de démontrer qu'il est dangereux et inutile de soumettre le choix de loi en matière de relations patrimoniales entre époux aux règles relatives aux conflits de nationalités. Il ... [more ▼]

Cette contribution tente de démontrer qu'il est dangereux et inutile de soumettre le choix de loi en matière de relations patrimoniales entre époux aux règles relatives aux conflits de nationalités. Il est au contraire démontré que lorsqu'une règle de droit international privé permet le choix de loi, celui-ci doit pouvoir porter sur l'une des nationalités que possède l'individu qui effectue le choix. [less ▲]

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See detailSolar wind interaction with the terrestrial planets
Garnier, P.; Milillo, A.; Radioti, Aikaterini ULg

in Planetary and Space Science (2015)

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See detailReturning home after Fukushima: Displacement from a nuclear disaster and international guidelines for internally displaced persons
Hasegawa, Reiko ULg

in Policy Brief Series: Migration, Environment and Climate Change (2015), 1(Issue 4),

This policy paper examines the case of displacement from the Fukushima nuclear disaster, with special focus on the question of return, from the perspective of international protection guidelines for ... [more ▼]

This policy paper examines the case of displacement from the Fukushima nuclear disaster, with special focus on the question of return, from the perspective of international protection guidelines for internally displaced persons (IDPs) [less ▲]

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See detailIdentification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Couffignal, Vincent et al

in Clinical physiology and functional imaging (2015), 35(5), 368-375

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]

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See detailEmbarrassment in the Posthumous Fiction of Janet Frame
Delrez, Marc ULg

in Journal of Postcolonial Writing (2015), 51(5), 579-90

It is generally assumed that Janet Frame suspended the publication of some of her work in her lifetime because it was felt to be deeply personal, or potentially embarrassing for people who might recognize ... [more ▼]

It is generally assumed that Janet Frame suspended the publication of some of her work in her lifetime because it was felt to be deeply personal, or potentially embarrassing for people who might recognize themselves in the portraits provided. These rationalizations fail to persuade, first because all of Frame’s published oeuvre anyway consists of a fictionalization of private existential matter, and the posthumous corpus hardly differs in this respect; and also because both Towards Another Sum- mer (2007) and In the Memorial Room (2013) feature a Kafkaesque concern with metamorphosis which serves to enhance the unrealistic tenor of the narratives, so that the novels again seem on a par with previously published self-conscious material. What is more distinctive about the new/old novels is less their allegedly embarrassing nature than their unusual degree of frontal engagement with the experience of embarrassment itself – their pondering of the pros and cons of shyness. This theme is addressed in aesthetic terms mostly. Frame’s artistic characters blush and squirm and writhe in ways which confirm the role played by embarrassment as an inadvertent recognition of, and an unwilling subscription to, an oppressive societal norm. Yet it can be shown that Frame, true to her customary dialectical mode of conceptualization, simultaneously uses embarrassment as a decentring strategy allowing the novels to work towards an exposure of so-called social normality. This exposure is achieved through a systematic policy of borrowing from, and testily reproducing, those very limited and limiting expressive codes which were found mortifying in the first place. [less ▲]

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See detailExploring the volatome of different cancer cell lines
Stefanuto, Pierre-Hugues ULg; Pesesse, Romain ULg; Bertrand, Virginie ULg et al

in European Respiratory Journal (2015), 46(suppl 59), 3975

As reported by the American Cancer Society, lung cancers have the highest death rate, compared to other types of cancer. The main reason is the lack of early stage non-invasive screening methods. Indeed ... [more ▼]

As reported by the American Cancer Society, lung cancers have the highest death rate, compared to other types of cancer. The main reason is the lack of early stage non-invasive screening methods. Indeed, the death rate of the other most abundant cancers is decreasing due to the implementation of large-scale population screening techniques. It is believed that the death rate of lung cancer could be lowered by developing and implementing more efficient diagnostic methods1. A large number of diseases appear to have a volatile signature present in exhaled air. In practice, analytical breath profiling offers solutions for early detection of different kind of lung infections2. For example, cystic fibrosis patients show a different volatile organic compound (VOC) profile because of the bacterial colonization that localizes in their lungs. A similar behavior is observed for patient suffering from lung cancer. However, the list of recognized volatile biomarkers of lung cancer is still scarce and could be improved. In spite of this, the biological variability of exhaled air profile makes the biomarkers identification challenging. In the hope of contributing to a better understanding, we used comprehensive two-dimensional gas chromatography coupled to time of light mass spectrometry (GC×GC-TOFMS) to investigate the headspace of cancer cells. A procedure has been developed to sample cell culture headspace. After proper data treatment, univariate and multivariate statistics were compared for isolation of potential cancer biomarkers. Further tentative identification was also carried out by using high-accuracy MS analyzers as detection techniques. 1 Siegel, R. et al. Cancer statistics 2013 2 Di Francesco, F. et al. Microchemical Journal 2005 . [less ▲]

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See detailSphenopalatine ganglion stimulation in neurovascular headaches
SCHOENEN, Jean ULg

in Progress in Neurological Surgery (2015), 29

Abstract The interest for the sphenopalatine ganglion (SPG) in neurovascular headaches dates back to 1908 when Sluder presented his work on the role of the sphenopalatine ganglion in «nasal headaches» ... [more ▼]

Abstract The interest for the sphenopalatine ganglion (SPG) in neurovascular headaches dates back to 1908 when Sluder presented his work on the role of the sphenopalatine ganglion in «nasal headaches» that are now part of the trigeminal autonomic cephalalgias and cluster headache (ICHD-III beta). Since then various interventions with blocking or lesional properties have targeted the SPG (transnasal injection of lidocaine and other agents, alcohol or steroid injections, radiofrequency lesions or even ganglionectomy); sucess rates varied, but benefit was usually transient. Here we briefly review some anatomo-physiological characteristics of the SPG and hypotheses about its pathophysiological role in neurovascular headaches before describing recent therapeutic results obtained with electrical stimulation of the SPG. Based on results of a prospective randomized controlled study, SPG stimulation appears to be an effective treatment option for patients with chronic cluster headaches; efficacy data indicate that acute electrical stimulation of the SPG provided significant attack pain relief and in many cases pain freedom compared to sham stimulation. Moreover, in some patients SPG stimulation was associated with a significant and clinically meaningful reduction in cluster headache attack frequency; this preventive effect of SPG stimulation warrants further investigation. For migraine attacks, the outcome of the proof-of-concept study using a temporary electrode implanted in the pterygopalatine fossa was less encouraging – but an ongoing multi-center trial evaluates the efficacy of long-term SPG stimulation against sham stimulation for acute and preventive treatment in patients with frequent migraine. [less ▲]

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See detailCompte rendu de Pardo (Céline), La poésie hors du livre (1945-1965). Le poème à l’ère de la radio et du disque
Huppe, Justine ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2015)

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See detailComparison of isotopic turnover dynamics in two different muscles of a coral reef fish during the settlement phase
Gajdzik, Laura ULg; Lepoint, Gilles ULg; Lecchini, David et al

in Scientia Marina (2015), 79(3), 325-333

The temporal variation in carbon and nitrogen isotopic compositions (noted as δ13C and δ15N) was investigated in the convict surgeonfish (Acanthurus triostegus) at Moorea (French Polynesia). Over a period ... [more ▼]

The temporal variation in carbon and nitrogen isotopic compositions (noted as δ13C and δ15N) was investigated in the convict surgeonfish (Acanthurus triostegus) at Moorea (French Polynesia). Over a period of 24 days, juveniles were reared in aquaria and subjected to two different feeding treatments: granules or algae. The dynamics of δ13C and δ15N in two muscles (the adductor mandibulae complex and the epaxial musculature) having different functions were compared. At the end of experiments, a steady-state isotopic system in each muscle tissue was not reached. Especially for the algal treatment, we found different patterns of variation in isotopic compositions over time between the two muscles. The turnovers of δ13C showed opposite trends for each muscle but differences are mitigated by starvation and by the metamorphosis. Our study highlighted that the metabolism of coral reef fish may be subjected to catabolism or anabolism of non-protein precursors at settlement, inducing variation in isotopic compositions that are not linked to diet change. [less ▲]

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See detailCulture in the post-2015 development agenda: the anatomy of an international mobilisation
Vlassis, Antonios ULg

in Third World Quarterly (2015), 36(9), 1649-1662

Throughout 2012–15 several actors were advocating that culture be explicitly integrated within the post-2015 UN development agenda. My article offers an anatomy of the recent international mobilisation in ... [more ▼]

Throughout 2012–15 several actors were advocating that culture be explicitly integrated within the post-2015 UN development agenda. My article offers an anatomy of the recent international mobilisation in order to understand the cleavages and the contrasting visions. In doing so, it seeks to analyse the policy process through which the agenda is made, why and how a critical mass of actors is attempting to embrace the inclusion of culture in the post-2015 agenda and the political reactions vis-à-vis this mobilisation. The article argues, on the one hand, that the promotion of culture in the post-2015 agenda is largely based on UNESCO’s will to advance its policy agenda and enhance its position within the UN system and, on the other hand, that this mobilisation lacks political support from the most influential governments; therefore its chances of success are more than contingent. [less ▲]

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See detailThe Petroglyphs of Huancor, Peru : Form and Meaning
Delnoÿ, David ULg; Otte, Marcel ULg

in EXPRESSION (2015), 9

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See detailSimilarities between the target and the intruder in naturally occurring repeated person naming errors
Brédart, Serge ULg; Dardenne, Benoît ULg

in Frontiers in Psychology (2015), 6(art 1474),

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See detailOutcome and risk factor analysis of molecular subgroups in cytogenetically normal AML treated by allogeneic transplantation
SCHMID, Christoph; LABOPIN, Myriam; SOCIE, Gerard et al

in Blood (2015)

Patients with cytogenetically normal acute myeloid leukemia (CN-AML) can be subdivided by molecular mutations. However, data on the influence of combinations of different aberrations on outcome after ... [more ▼]

Patients with cytogenetically normal acute myeloid leukemia (CN-AML) can be subdivided by molecular mutations. However, data on the influence of combinations of different aberrations on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) is limited. Therefore, we performed a retrospective registry analysis on 702 adults with CNAML undergoing HSCT in first complete remission (CR). Patients were grouped according to presence or absence of NPM1 mutations (NPM1mut) and FLT3 internal tandem duplications (FLT3-ITD). Double negative patients were evaluated for mutations of the CCAAT/enhancer binding protein α gene (CEBPα). The influence of genotypes on relapse, non-relapse mortality, leukemia-free survival (LFS) and overall survival (OS), and a prognostic classification combining NPM1/FLT3-ITD profile and classical risk factors were calculated. 2y-OS from HSCT was 81±5% in NPM1mut/FLT3wt (n=68), 75±3% in NPM1wt/FLT3wt (n=290), 66±3% in NPM1mut/FLT3-ITD (n=269) and 54±7% in NPM1wt/FLT3-ITD (n=75; p=0.003). Analysis of CEBPα among patients with NPM1wt/FLT3wt revealed excellent results both in patients with CEBPα mut (n=13, 2y-OS:100%), and with a triple negative genotype (n=138, 2y-OS:77±3%). In a Cox-model of predefined factors, older age, presence of FLT3-ITD and >1 course of chemotherapy to reach CR were associated with inferior outcome. 2y-OS/LFS were 88±3%/79±4% in patients without any, 77±2%/73±3% with one, and 53±4%/50±4 with>=2 risk factors (p=0.002 for LFS, p=0.003 for OS). Hence, FLT3-ITD proofed to be the decisive molecular marker for outcome after HSCT for CN-AML in CR1, regardless of NPM1 mutational status, variations of transplant protocols, or development of GvHD. Age, FLT3-ITD and response to induction chemotherapy allow for a prognostic risk classification. [less ▲]

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See detailInfluence du Kinésiotape® sur les performances musculaires des ischio-jambiers
BAUVIR, Philippe ULg; Kaux, Jean-François ULg; Pondant, Laurent et al

in Journal de Traumatologie du Sport (2015), 32(3), 110-115

Objective The aim of this controlled, randomized, and double-blind study was to determine whether Kinesiotape® placed on healthy hamstrings could influence the isokinetic performances of this muscle group ... [more ▼]

Objective The aim of this controlled, randomized, and double-blind study was to determine whether Kinesiotape® placed on healthy hamstrings could influence the isokinetic performances of this muscle group and of its antagonist, the quadriceps. Methods Twelve healthy men, aged 18–30 years, were subjected to an isokinetic evaluation in 3 different conditions (without Kinesiotape®, placebo Kinesiotape® to hamstrings, facilitation Kinesiotape® to hamstrings) in randomized order. The 3 sessions assessed peak torque (N.m), work (J) and angle to peak torque (°) in concentric 60 and 240°/s for hamstrings and quadriceps, and in eccentric 30°/s for hamstrings. Results Isokinetic performances in the 3 different conditions were not significantly different (P>0.05) in particular for the hamstrings concentric and eccentric peak torques. Only the angle to peak torque for hamstrings in eccentric 30°/s was modified when comparing placebo Kinesiotape® with no Kinesiotape® condition (P<0.05). Conclusion Kinesiotape® intervention in healthy subjects’ hamstrings did not influence neither the strength of this muscular group nor the performances of its antagonist, the quadriceps. [less ▲]

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See detailAn enhanced version of a bone remodelling model based on the continuum damage mechanics theory.
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg

in Computer Methods in Biomechanics & Biomedical Engineering (2015), 18(12), 1367-1376

The purpose of this work is to propose an enhancement of Doblaré and García's internal bone remodelling model based on the continuum damage mechanics theory. In their paper, they stated that the evolution ... [more ▼]

The purpose of this work is to propose an enhancement of Doblaré and García's internal bone remodelling model based on the continuum damage mechanics theory. In their paper, they stated that the evolution of the internal variables of the bone microstructure, and its incidence on the modification of the elastic constitutive parameters, may be formulated following the principles of Continuum Damage Mechanics, although no actual damage was considered. The resorption and apposition criteria (similar to the damage criterion) were expressed in terms of a mechanical stimulus. However, the resorption criterion is lacking a dimensional consistency with the remodelling rate. We here propose an enhancement to this resorption criterion, insuring the dimensional consistency while retaining the physical properties of the original remodelling model. We then analyse the change in the resorption criterion hypersurface in the stress space for a 2D analysis. We finally apply the new formulation to analyse the structural evolution of a 2D femur. This analysis gives results consistent with the original model but with a faster and more stable convergence rate. [less ▲]

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See detailStress, psychosocial mediators and cognitive mediators in parents of child cancer patients and cancer survivors: Attention and working memory pathway perspectives
Vander Haegen, Marie ULg; Luminet, Olivier

in The Journal Of Psychosocial Oncology (2015), 33

Objective: This review examines stress and its consequences on attention and working memory, stress symptoms in parents of child cancer patients and survivors and long term consequences of stress on ... [more ▼]

Objective: This review examines stress and its consequences on attention and working memory, stress symptoms in parents of child cancer patients and survivors and long term consequences of stress on cognitive processing in parents of child cancer survivors. Method: Eligible studies were experimental, meta-analyses and qualitative (2000–2013) from Pubmed, Medline, the Cochrane Library, PsycArticles and Google Scholar. Results: We identified 92 eligible papers. They showed that elevated stress can impede performances on tasks requiring attention and memory patterns. In paediatric oncology, parental stress increased shortly after diagnosis involving depression and anxiety. Consequences of stress on cognitive performances were observed mainly among depressed individuals. As regards parents of child cancer survivors, female gender, low SES, innate traits of anxiety/anger predicted the development of PTSS. Conclusion: Evidence of stress on attention and working memory processes in parents of child cancer survivors is insufficient developed. [less ▲]

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See detailIntérêts de retard sur une dette de valeur
Biquet, Christine ULg

in Journal des Juges de Paix = Tijdschrift van de Vrederecters (2015), (9-10), 526-531

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See detailPRISE EN CHARGE DU CANCER BRONCHIQUE NON A PETITES CELLULES.
SIBILLE, Anne ULg; PAULUS, Astrid ULg; MARTIN, Marie ULg et al

in Revue Médicale de Liège (2015), 70(9), 432-41

Already known as the first cause of mortality in men, non-small cell lung cancer (NSCLC) is nowadays a major cause of cancer-related death in women. Its approach relies on a thorough locoregional and ... [more ▼]

Already known as the first cause of mortality in men, non-small cell lung cancer (NSCLC) is nowadays a major cause of cancer-related death in women. Its approach relies on a thorough locoregional and extra-thoracic assessment allowing a precise staging which not only has prognostic value, but also determines the therapeutic options. This review presents the current multidisciplinary strategy agreement or the treatment of NSCLC. [less ▲]

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See detailSmart Grid Energy Flexible Buildings through the use of Heat Pumps and Building Thermal Mass as Energy Storage in the Belgian context
Masy, Gabrielle; Georges, Emeline ULg; Verhelst, Clara et al

in Science and Technology for the Built Environment (2015), 21(6), 800-811

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See detailRiver geochemistry, chemical weathering, and atmospheric CO2 consumption rates in the Virunga Volcanic Province (East Africa)
Balagizi, Charles M.; Darchambeau, François ULg; Bouillon, Steven et al

in Geochemistry, Geophysics, Geosystems (2015), 16

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See detailOccupational stress among textile workers in the Democratic Republic of Congo
Panda Lukongo, Kitronza ULg; Mairiaux, Philippe ULg

in Tropical Medicine and Health (2015), Tropical Medicine and Health , 2015,(Vol. 43 No.4), 223231

Context: In the Democratic Republic of Congo (DRC), scientific studies on occupational health are scarce. The present study aims at estimating the level of occupational stress, as well as associated ... [more ▼]

Context: In the Democratic Republic of Congo (DRC), scientific studies on occupational health are scarce. The present study aims at estimating the level of occupational stress, as well as associated factors, in a textile company. Methods: We performed a cross-sectional survey among textile workers in DRC. Data (N= 192 subjects) were collected through a self-questionnaire validated for the assessment of stress (Karasek and Siegrist’s scale); supplemented by a medical examination. Frequencies and odds ratios (ORs) were estimated for descriptive analyses. Adjusted ORs were calculated through a logistic regression model to investigate associations between socio-demographic and organisational variable and stress. Results: Our study highlighted a high level of stress among individuals: 28% of them were suffering from stress, according to Karasek, and 22%, when applying Siegrist’s model. A 14%-isostrain was calculated when considering all workers. A statistically significant association was observed between stress and age, seniority and perceived no-adaptation to work, considering both approaches. Furthermore, when job strain was determined according to Karasek, it was related to the status of worker, the poor perception of organisation and alcohol consumption, while stress estimated by applying Siegrist’s model showed an association with education level and the occurrence of cardiac symptoms. Conclusion: The present study gives evidence of stress among individuals through both models. Several socio-professional factors are associated with stress, which determines populations at risk. The study revealed that both stress models offer complementary information, thus increasing the probability to model workers’ health more exactly and to make recommendations on prevention and management. [less ▲]

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See detailUltrafast and Distinct Spin Dynamics in Magnetic Alloys
Radu, I.; Stamm, C.; Eschenlohr, A. et al

in Spin (2015), 5(3), 1550004

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See detailDetection of anthropogenic particles in fish stomachs: an isolation method adapted to identification by Raman spectroscopy
Collard, France ULg; Gilbert, Bernard ULg; Eppe, Gauthier ULg et al

in Archives of Environmental Contamination & Toxicology (2015), 69

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See detailCentury-scale simulations of the response of the West Antarctic Ice Sheet to a warming climate
Cornford, S.L.; Martin, D.F.; Payne, A.J. et al

in Cryosphere (The) (2015), 9

We use the BISICLES adaptive mesh ice sheet model to carry out one, two, and three century simulations of the fast-flowing ice streams of the West Antarctic Ice Sheet, deploying sub-kilometer resolution ... [more ▼]

We use the BISICLES adaptive mesh ice sheet model to carry out one, two, and three century simulations of the fast-flowing ice streams of the West Antarctic Ice Sheet, deploying sub-kilometer resolution around the grounding line since coarser resolution results in substantial underestimation of the response. Each of the simulations begins with a geometry and velocity close to present-day observations, and evolves according to variation in meteoric ice accumulation rates and oceanic ice shelf melt rates. Future changes in accumulation and melt rates range from no change, through anomalies computed by atmosphere and ocean models driven by the E1 and A1B emissions scenarios, to spatially uniform melt rate anomalies that remove most of the ice shelves over a few centuries. We find that variation in the resulting ice dynamics is dominated by the choice of initial conditions and ice shelf melt rate and mesh resolution, although ice accumulation affects the net change in volume above flotation to a similar degree. Given sufficient melt rates, we compute grounding line retreat over hundreds of kilometers in every major ice stream, but the ocean models do not predict such melt rates outside of the Amundsen Sea Embayment until after 2100. Within the Amundsen Sea Embayment the largest single source of variability is the onset of sustained retreat in Thwaites Glacier, which can triple the rate of eustatic sea level rise. [less ▲]

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See detailSeeing Central African forests through their largest trees
Bastin, Jean-François ULg; Barbier, Nicolas; Réjou-Méchain, Maxime et al

in Scientific Reports (2015)

Large tropical trees and a few dominant species were recently identified as the main structuring elements of tropical forests. However, such result did not translate yet into quantitative approaches which ... [more ▼]

Large tropical trees and a few dominant species were recently identified as the main structuring elements of tropical forests. However, such result did not translate yet into quantitative approaches which are essential to understand, predict and monitor forest functions and composition over large, often poorly accessible territories. Here we show that the above-ground biomass (AGB) of the whole forest can be predicted from a few large trees and that the relationship is proved strikingly stable in 175 1-ha plots investigated across 8 sites spanning Central Africa. We designed a generic model predicting AGB with an error of 14% when based on only 5% of the stems, which points to universality in forest structural properties. For the first time in Africa, we identified some dominant species that disproportionally contribute to forest AGB with 1.5% of recorded species accounting for over 50% of the stock of AGB. Consequently, focusing on large trees and dominant species provides precise information on the whole forest stand. This offers new perspectives for understanding the functioning of tropical forests and opens new doors for the development of innovative monitoring strategies. [less ▲]

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See detailDesign of hybrid nanovehicles for remotely triggered drug release: an overview
Liu, Ji; Detrembleur, Christophe ULg; Mornet, Stéphane et al

in Journal of Materials Chemistry B (2015), 3(30), 6117-6147

n the past few decades, various nanovehicles have been developed as drug delivery systems, in which inorganic and organic components are integrated within a nano-object. Upon the application of remote ... [more ▼]

n the past few decades, various nanovehicles have been developed as drug delivery systems, in which inorganic and organic components are integrated within a nano-object. Upon the application of remote stimuli, e.g. alternating magnetic field, near infrared or ultrasound radiations, the release of guest molecules can be triggered in a quite controlled manner. Herein, we review different hybrid nanostructures which have already been reported for the remotely triggered release, such as those based on (1) host–guest conjugates, (2) core–corona nanoparticles, (3) polymer nanogels, (4) polymer micelles, (5) liposomes, (6) mesoporous silica particles and (7) hollow nanoparticles. Moreover, we also summarize six underlying mechanisms that govern such a kind of remotely triggered release behaviours: (1) enhanced diffusion and/or permeation, (2) thermo- or photo-labile bond cleavage, (3) fusion of phase-changed materials, (4) photo-induced isomerisation, (5) thermo-induced swelling/de-swelling of thermo-responsive polymers, and (6) destruction of the nanostructures. The ways in which different components are incorporated into an integrated hybrid nanostructure and how they contribute to the remotely triggered release behaviours are detailed. [less ▲]

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See detailInterlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping
Wenz, Christian; Barbas, Coral; Lopez-Gonzalvez, Angeles et al

in Journal of Separation Science (2015)

A collaborative study on the robustness and portability of a capillary electrophoresis-mass spectrometry method for peptide mapping was performed by an international team, consisting of 13 independent ... [more ▼]

A collaborative study on the robustness and portability of a capillary electrophoresis-mass spectrometry method for peptide mapping was performed by an international team, consisting of 13 independent laboratories from academia and industry. All participants used the same batch of samples, reagents and coated capillaries to run their assays, whereas they utilized the capillary electrophoresis-mass spectrometry equipment available in their laboratories. The equipment used varied in model, type and instrument manufacturer. Furthermore, different types of sheath-flow capillary electrophoresis–mass spectrometry interfaces were used. Migration time, peak height and peak area of ten representative target peptides of trypsin-digested bovine serum albumin were determined by every laboratory on two consecutive days. The data were critically evaluated to identify outliers and final values for means, repeatability (precision within a laboratory) and reproducibility (precision between laboratories) were established. For relative migration time the repeatability was between 0.05 and 0.18% RSD and the reproducibility between 0.14 and 1.3% RSD. For relative peak area repeatability and reproducibility values obtained were 3–12 and 9–29% RSD, respectively. These results demonstrate that capillary electrophoresis-mass spectrometry is robust enough to allow a method transfer across multiple laboratories and should promote a more widespread use of peptide mapping and other capillary electrophoresis-mass spectrometry applications in biopharmaceutical analysis and related fields. [less ▲]

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See detailAll Poly(ionic liquid)-based block copolymers by sequential controlled radical copolymerization of vinylimidazolium monomers
Cordella, Daniela ULg; Kermagoret, Anthony; Debuigne, Antoine ULg et al

in Macromolecules (2015), 48(15), 5230-5243

The organometallic-mediated radical polymerization (OMRP) of N-vinyl-3-alkylimidazolium-type monomers, featuring the bis(trifluoromethylsulfonyl)imide counteranion (Tf2N–), in the presence of Co(acac)2 as ... [more ▼]

The organometallic-mediated radical polymerization (OMRP) of N-vinyl-3-alkylimidazolium-type monomers, featuring the bis(trifluoromethylsulfonyl)imide counteranion (Tf2N–), in the presence of Co(acac)2 as controlling agent, is reported. Polymerizations of monomers with methyl, ethyl, and butyl substituents are fast, reaching high monomer conversion in ethyl acetate as solvent at 30 °C, and afford structurally well-defined hydrophobic poly(ionic liquid)s (PILs) of N-vinyl type. Block copolymer synthesis is also achieved by sequential OMRP of N-vinyl-3-alkylimidazolium salts carrying different alkyl chains and different counteranions (Tf2N– or Br–). These block copolymerizations are carried out at 30 °C, either under homogeneous solution in methanol or in a biphasic medium consisting of a mixture of ethyl acetate and water. Unprecedented PIL-b-PIL block copolymers are thus prepared under these conditions. However, anion exchange occurs at the early stage of the growth of the second block. Finally, diblock copolymers generated in the biphasic medium can be readily coupled by addition of isoprene, forming all PIL-based and symmetrical ABA-type triblock copolymers in a one-pot process. Such a direct block copolymerization method, involving vinylimidazolium monomers bearing different alkyl chains, thus opens new opportunities in the precision synthesis of all PIL-based block copolymers of tunable properties. [less ▲]

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See detailRecent changes in north-west Greenland climate documented by NEEM shallow ice core data and simulations, and implications for past-temperature reconstructions
Masson-Delmotte, V.; Steen-Larsen, H.; Ortega, P. et al

in Cryosphere (The) (2015), 9

Combined records of snow accumulation rate, δ18O and deuterium excess were produced from several shallow ice cores and snow pits at NEEM (North Greenland Eemian Ice Drilling), covering the period from ... [more ▼]

Combined records of snow accumulation rate, δ18O and deuterium excess were produced from several shallow ice cores and snow pits at NEEM (North Greenland Eemian Ice Drilling), covering the period from 1724 to 2007. They are used to investigate recent climate variability and characterise the isotope–temperature relationship. We find that NEEM records are only weakly affected by inter-annual changes in the North Atlantic Oscillation. Decadal δ18O and accumulation variability is related to North Atlantic sea surface temperature and is enhanced at the beginning of the 19th century. No long-term trend is observed in the accumulation record. By contrast, NEEM δ18O shows multidecadal increasing trends in the late 19th century and since the 1980s. The strongest annual positive δ18O values are recorded at NEEM in 1928 and 2010, while maximum accumulation occurs in 1933. The last decade is the most enriched in δ18O (warmest), while the 11-year periods with the strongest depletion (coldest) are depicted at NEEM in 1815–1825 and 1836–1846, which are also the driest 11-year periods. The NEEM accumulation and δ18O records are strongly correlated with outputs from atmospheric models, nudged to atmospheric reanalyses. Best performance is observed for ERA reanalyses. Gridded temperature reconstructions, instrumental data and model outputs at NEEM are used to estimate the multidecadal accumulation–temperature and δ18O–temperature relationships for the strong warming period in 1979–2007. The accumulation sensitivity to temperature is estimated at 11 ± 2 % °C−1 and the δ18O–temperature slope at 1.1 ± 0.2 ‰ °C−1, about twice as large as previously used to estimate last interglacial temperature change from the bottom part of the NEEM deep ice core. [less ▲]

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See detailLa lutte contre les moustiques (Diptera: Culicidae): diversité des approches et application du contrôle biologique
Bawin, Thomas ULg; Seye, Fawrou; Boukraa, Slimane ULg et al

in Canadian Entomologist (2015), 147(4), 476-500

Many mosquito (Diptera: Culicidae) species are zoonotic vectors responsible for numerous infectious diseases of medical and veterinary importance. Currently, changes in the vectors’ geographical ... [more ▼]

Many mosquito (Diptera: Culicidae) species are zoonotic vectors responsible for numerous infectious diseases of medical and veterinary importance. Currently, changes in the vectors’ geographical distribution induced chiefly by anthropogenic factors are accompanied by emerging and reemerging infectious diseases in Europe and North America. Since the advent of synthetic insecticides during the Second World War, mosquitoes are the object of considerably expanded and deepened research. In an integrated pest management context, means of control are now mainly classified as: (1) environmental management and physical control, (2) chemical control, (3) genetic control, and (4) biological control by means of entomophagous predators and entomopathogenic microorganisms. In this context, these last have significant potential because of their ability to infect and kill their host with more or less targeted selectivity. This article proposes to emphasize biological control among other techniques in mosquito control, and to assess the potential and the opportunities offered by entomopathogenic bacteria, viruses and fungi. Finally, their use as biopesticides is discussed. [less ▲]

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See detailGenome-wide hydroxymethylcytosine pattern changes in response to oxidative stress.
Delatte, Benjamin; Jeschke, Jana; Defrance, Matthieu et al

in Scientific reports (2015), 5

The TET enzymes convert methylcytosine to the newly discovered base hydroxymethylcytosine. While recent reports suggest that TETs may play a role in response to oxidative stress, this role remains ... [more ▼]

The TET enzymes convert methylcytosine to the newly discovered base hydroxymethylcytosine. While recent reports suggest that TETs may play a role in response to oxidative stress, this role remains uncertain, and results lack in vivo models. Here we show a global decrease of hydroxymethylcytosine in cells treated with buthionine sulfoximine, and in mice depleted for the major antioxidant enzymes GPx1 and 2. Furthermore, genome-wide profiling revealed differentially hydroxymethylated regions in coding genes, and intriguingly in microRNA genes, both involved in response to oxidative stress. These results thus suggest a profound effect of in vivo oxidative stress on the global hydroxymethylome. [less ▲]

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See detailModels of red giants in the CoRoT asteroseismology fields combining asteroseismic and spectroscopic constraints
Lagarde, N.; Miglio, A.; Eggenberger, P. et al

in Astronomy and Astrophysics (2015), 580

Context. The availability of asteroseismic constraints for a large sample of red giant stars from the CoRoT and Kepler missions paves the way for various statistical studies of the seismic properties of ... [more ▼]

Context. The availability of asteroseismic constraints for a large sample of red giant stars from the CoRoT and Kepler missions paves the way for various statistical studies of the seismic properties of stellar populations. <BR /> Aims: We use a detailed spectroscopic study of 19 CoRoT red giant stars to compare theoretical stellar evolution models to observations of the open cluster NGC 6633 and field stars. <BR /> Methods: In order to explore the effects of rotation-induced mixing and thermohaline instability, we compare surface abundances of carbon isotopic ratio and lithium with stellar evolution predictions. These chemicals are sensitive to extra-mixing on the red giant branch. <BR /> Results: We estimate mass, radius, and distance for each star using the seismic constraints. We note that the Hipparcos and seismic distances are different. However, the uncertainties are such that this may not be significant. Although the seismic distances for the cluster members are self consistent they are somewhat larger than the Hipparcos distance. This is an issue that should be considered elsewhere. Models including thermohaline instability and rotation-induced mixing, together with the seismically determined masses can explain the chemical properties of red giant targets. However, with this sample of stars we cannot perform stringent tests of the current stellar models. Tighter constraints on the physics of the models would require the measurement of the core and surface rotation rates, and of the period spacing of gravity-dominated mixed modes. A larger number of stars with longer times series, as provided by Kepler or expected with Plato, would help ensemble asteroseismology. [less ▲]

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See detailA Coordinated X-Ray and Optical Campaign of the Nearest Massive Eclipsing Binary, δ Orionis Aa. I. Overview of the X-Ray Spectrum
Corcoran, M. F.; Nichols, J. S.; Pablo, H. et al

in Astrophysical Journal (2015), 809

We present an overview of four deep phase-constrained Chandra HETGS X-ray observations of δ Ori A. Delta Ori A is actually a triple system that includes the nearest massive eclipsing spectroscopic binary ... [more ▼]

We present an overview of four deep phase-constrained Chandra HETGS X-ray observations of δ Ori A. Delta Ori A is actually a triple system that includes the nearest massive eclipsing spectroscopic binary, δ Ori Aa, the only such object that can be observed with little phase-smearing with the Chandra gratings. Since the fainter star, δ Ori Aa2, has a much lower X-ray luminosity than the brighter primary (δ Ori Aa1), δ Ori Aa provides a unique system with which to test the spatial distribution of the X-ray emitting gas around δ Ori Aa1 via occultation by the photosphere of, and wind cavity around, the X-ray dark secondary. Here we discuss the X-ray spectrum and X-ray line profiles for the combined observation, having an exposure time of nearly 500 ks and covering nearly the entire binary orbit. The companion papers discuss the X-ray variability seen in the Chandra spectra, present new space-based photometry and ground-based radial velocities obtained simultaneously with the X-ray data to better constrain the system parameters, and model the effects of X-rays on the optical and UV spectra. We find that the X-ray emission is dominated by embedded wind shock emission from star Aa1, with little contribution from the tertiary star Ab or the shocked gas produced by the collision of the wind of Aa1 against the surface of Aa2. We find a similar temperature distribution to previous X-ray spectrum analyses. We also show that the line half-widths are about 0.3‑0.5 times the terminal velocity of the wind of star Aa1. We find a strong anti-correlation between line widths and the line excitation energy, which suggests that longer-wavelength, lower-temperature lines form farther out in the wind. Our analysis also indicates that the ratio of the intensities of the strong and weak lines of Fe xvii and Ne x are inconsistent with model predictions, which may be an effect of resonance scattering. [less ▲]

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See detailThe Airline Container Loading Problem with Pickup and Delivery
Lurkin, Virginie ULg; Schyns, Michael ULg

in European Journal of Operational Research (2015), 244(3), 955-965

This paper considers the loading optimization problem for a set of containers and pallets transported into a cargo aircraft that serves multiple airports. Because of pickup and delivery operations that ... [more ▼]

This paper considers the loading optimization problem for a set of containers and pallets transported into a cargo aircraft that serves multiple airports. Because of pickup and delivery operations that occur at intermediate airports, this problem is simultaneously a Weight & Balance Problem and a Sequencing Problem. Our objective is to minimize fuel and handling operation costs. This problem is shown to be NP-hard. We resort to a mixed integer linear program. Based on real-world data from a professional partner (TNT Airways), we perform numerical experiments using a standard B&C library. This approach yields better solutions than traditional manual planning, which results in substantial cost savings. [less ▲]

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See detailOptical study of diffraction grating/Fresnel lens combinations applied to a spectral-splitting solar concentrator for space applications
Michel, Céline ULg; Loicq, Jerôme ULg; Thibert, Tanguy ULg et al

in Applied Optics (2015), 54(22), 6666-6673

This paper presents a new design of a planar solar concentrator with spectral splitting of light for space applications. This concentrator spectrally splits the incident light into mainly two parts. Each ... [more ▼]

This paper presents a new design of a planar solar concentrator with spectral splitting of light for space applications. This concentrator spectrally splits the incident light into mainly two parts. Each part is then focused onto specific spatially separated photovoltaic cells, allowing for independent control of respective cells output power. These advantages of both spectral splitting and light focusing are here combined thanks to a specific diffraction grating superimposed on a Fresnel lens. The theoretical principle of the optical design is presented, with optimization of each element and improvement steps, including optimization of grating period evolution along the lens, and testing of two kinds of gratings (a blazed and a lamellar one). First numerical results are presented, highlighting the possibility to design a concentrator at about 10× or more for each cell, with an output power larger than that of a classical concentrator focusing on a GaAs SJ cell, and less than 10% of losses for tracking errors up to ±0.8°. Some experimental results are also presented. [less ▲]

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See detailHigh-resolution spectra of comet C/2013 R1 (Lovejoy)
Rousselot, P.; Decock, A.; Korsun, P. P. et al

in Astronomy and Astrophysics (2015), 580

Context. High-resolution spectra of comets permit deriving the physical properties of the coma. In the optical range, relative production rates can be computed, and information about isotopic ratios and ... [more ▼]

Context. High-resolution spectra of comets permit deriving the physical properties of the coma. In the optical range, relative production rates can be computed, and information about isotopic ratios and the origin of oxygen atoms can be obtained. <BR /> Aims: The main objective of the work presented here was to obtain information about the chemical composition of comet C/2013 R1 (Lovejoy), a bright and long-period comet that passed perihelion (0.81 au) on 22 December 2013. <BR /> Methods: We used the HARPS-North echelle spectrograph at the 3.5 m telescope TNG to obtain high-resolution spectra of comet C/2013 R1 (Lovejoy) in the optical range immediately after its perihelion passage during four consecutive nights in the period December 23 to 26, 2013. <BR /> Results: Our results demonstrate the ability of HARPS-North to efficiently obtain cometary spectra. Very faint emission lines, such as those of [SUP]15[/SUP]NH[SUB]2[/SUB], have been detected, leading to a rough estimate of the [SUP]14[/SUP]N/[SUP]15[/SUP]N ratio in NH[SUB]2[/SUB]. The [SUP]12[/SUP]C/[SUP]13[/SUP]C ratio was measured in the C[SUB]2[/SUB] lines and is equal to 80 ± 30. The oxygen lines were studied as well (green to red line intensity ratios and widths), confirming that H[SUB]2[/SUB]O is the main parent molecule that photodissociates to produce oxygen atoms. This suggests that this comet has a high CO[SUB]2[/SUB] abundance. Relative production rates for C[SUB]2[/SUB] and NH[SUB]2[/SUB] were computed, but we found no significant deviation from a typical NH[SUB]2[/SUB]/C[SUB]2[/SUB] ratio. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the INAF (Istituto Nazionale di Astrofisica) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. [less ▲]

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See detailA Coordinated X-Ray and Optical Campaign of the Nearest Massive Eclipsing Binary, δ Orionis Aa. II. X-Ray Variability
Nichols, J.; Huenemoerder, D. P.; Corcoran, M. F. et al

in Astrophysical Journal (2015), 809

We present time-resolved and phase-resolved variability studies of an extensive X-ray high-resolution spectral data set of the δ Ori Aa binary system. The four observations, obtained with Chandra ACIS ... [more ▼]

We present time-resolved and phase-resolved variability studies of an extensive X-ray high-resolution spectral data set of the δ Ori Aa binary system. The four observations, obtained with Chandra ACIS HETGS, have a total exposure time of ≈ 479 ks and provide nearly complete binary phase coverage. Variability of the total X-ray flux in the range of 5–25 Å is confirmed, with a maximum amplitude of about ±15% within a single ≈ 125 ks observation. Periods of 4.76 and 2.04 days are found in the total X-ray flux, as well as an apparent overall increase in the flux level throughout the nine-day observational campaign. Using 40 ks contiguous spectra derived from the original observations, we investigate the variability of emission line parameters and ratios. Several emission lines are shown to be variable, including S xv, Si xiii, and Ne ix. For the first time, variations of the X-ray emission line widths as a function of the binary phase are found in a binary system, with the smallest widths at ϕ = 0.0 when the secondary δ Ori Aa2 is at the inferior conjunction. Using 3D hydrodynamic modeling of the interacting winds, we relate the emission line width variability to the presence of a wind cavity created by a wind–wind collision, which is effectively void of embedded wind shocks and is carved out of the X-ray-producing primary wind, thus producing phase-locked X-ray variability. Based on data from the Chandra X-ray Observatory and the MOST satellite, a Canadian Space Agency mission, jointly operated by Dynacon Inc., the University of Toronto Institute of Aerospace Studies, and the University of British Columbia, with the assistance of the University of Vienna. [less ▲]

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See detailSimultaneous X-ray and optical spectroscopy of the Oef supergiant λ Cephei
Rauw, Grégor ULg; Hervé, A.; Nazé, Yaël ULg et al

in Astronomy and Astrophysics (2015), 580

Probing the structures of stellar winds is of prime importance for the understanding of massive stars. Based on their optical spectral morphology and variability, it has been suggested that the stars in ... [more ▼]

Probing the structures of stellar winds is of prime importance for the understanding of massive stars. Based on their optical spectral morphology and variability, it has been suggested that the stars in the Oef class feature large-scale structures in their wind. High-resolution X-ray spectroscopy and time-series of X-ray observations of presumably single O-type stars can help us understand the physics of their stellar winds. We have collected XMM-Newton observations and coordinated optical spectroscopy of the O6 Ief star λ Cep to study its X-ray and optical variability and to analyse its high-resolution X-ray spectrum. We investigate the line profile variability of the He ii λ 4686 and Hα emission lines in our time series of optical spectra, including a search for periodicities. We further discuss the variability of the broadband X-ray flux and analyse the high-resolution spectrum of λ Cep using line-by-line fits as well as a code designed to fit the full high-resolution X-ray spectrum consistently. During our observing campaign, the He ii λ 4686 line varies on a timescale of ~18 h. On the contrary, the Hα line profile displays a modulation on a timescale of 4.1 days which is likely the rotation period of the star. The X-ray flux varies on timescales of days and could in fact be modulated by the same 4.1-day period as Hα, although both variations are shifted in phase. The high-resolution X-ray spectrum reveals broad and skewed emission lines as expected for the X-ray emission from a distribution of wind-embedded shocks. Most of the X-ray emission arises within less than 2 R∗ above the photosphere. The properties of the X-ray emission of λ Cep generally agree with the expectations of the wind-embedded shock model. There is mounting evidence for the existence of large-scale structures that modulate the Hα line and about 10% of the X-ray emission of λ Cep. [less ▲]

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See detailWhat effects do rater bias and assessment method haveon disease severity estimation with regard to hypothesis testing?
Chiang, Kuo-Szu; Bock, Clive; El Jarroudi, Moussa ULg et al

in Plant Pathology (2015)

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See detailPreovulatory follicle diameter, growth rate and time of ovulation during induced oestrus using a CIDR® in trypanotolerant female Bos taurus N'Dama cattle.
Okouyi, M'foumou W'otari Marcel; Drion, Pierre ULg; Hanzen, Christian ULg

in Tropical Animal Health and Production (2015), 47

The aim of this study was to assess the dose (300 to 600 IU) effects of equine Chorionic Gonadotropin (eCG) on the preovulatory follicle diameter, growth rate, and time of ovulation characterized by ... [more ▼]

The aim of this study was to assess the dose (300 to 600 IU) effects of equine Chorionic Gonadotropin (eCG) on the preovulatory follicle diameter, growth rate, and time of ovulation characterized by echography. The eCG was injected at the end (D0) of the 7-day treatment with a controlled internal device release (CIDR) and a PGF2a being injected 2 days before the removal of the CIDR (D-2). The 120 female N'Dama cattle were distributed into five experimental groups. The control group (n = 26) was treated with physiological saline at the removal of the CIDR®, while the animals in the four treated groups received, respectively, 300 IU (n = 25), 400 IU (n = 24), 500 IU (n = 22) and 600 IU (n = 23) of eCG (Folligon®). Follicle growth rate (FGR) was significantly (P < 0.05) higher in animals treated using eCG (1.0 ± 0.4mm/day) than in the control group (0.9 ± 0.4mm/day). The diameter of the preovulatory follicle was significantly higher (P < 0.05) in the animals treated with 300 IU (10.1 ± 1.4mm) than in untreated animals (9.3 ± 1.2mm). Follicle growth rate was significantly higher (P<0.05) inn the animals treated with 300 IU (10,1 ± 1,4 mm) than in the control group (0.9±0,4 mm/day). The average interval between the time of eCG injection and ovulation was similar in the non-treated (83.7 ± 14.4 h) and treated animals (79.7 ± 11.9). Treated animals sowed a significant increase in the percentga of ovulation (94,7 %) compared to 73,1 %) (P<0.01). Use of eCG combined contributed towards synchronising the time of ovulation between 72 to 96 hours, which would facilitate the use of systematic insemination. [less ▲]

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See detailTime series of high-resolution spectra of SN 2014J observed with the TIGRE telescope
Jack, D.; Mittag, M.; Schröder, K.-P. et al

in Monthly Notices of the Royal Astronomical Society (2015), 451

We present a time series of high-resolution spectra of the Type Ia supernova 2014J, which exploded in the nearby galaxy M82. The spectra were obtained with the HEROS échelle spectrograph installed at the ... [more ▼]

We present a time series of high-resolution spectra of the Type Ia supernova 2014J, which exploded in the nearby galaxy M82. The spectra were obtained with the HEROS échelle spectrograph installed at the 1.2-m TIGRE telescope. We present a series of 33 spectra with a resolution of R ≈ 20 000, which covers the important bright phases in the evolution of SN 2014J during the period from 2014 January 24 to April 1. The spectral evolution of SN 2014J is derived empirically. The expansion velocities of the Si II P-Cygni features were measured and show the expected decreasing behaviour, beginning with a high velocity of 14 000 km s[SUP]-1[/SUP] on January 24. The Ca II infrared triplet feature shows a high-velocity component with expansion velocities of >20 000 km s[SUP]-1[/SUP] during the early evolution apart from the normal component showing similar velocities as Si II. Further broad P-Cygni profiles are exhibited by the principal lines of Ca II, Mg II and Fe II. The TIGRE SN 2014J spectra also resolve several very sharp Na I D doublet absorption components. Our analysis suggests interesting substructures in the interstellar medium of the host galaxy M82, as well as in our Milky Way, confirming other work on this SN. We were able to identify the interstellar absorption of M82 in the lines of Ca II H & K at 3933 and 3968 Å as well as K I at 7664 and 7698 Å. Furthermore, we confirm several diffuse interstellar bands, at wavelengths of 6196, 6283, 6376, 6379and 6613 Å and give their measured equivalent widths. [less ▲]

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See detailA force sensor based on three weakly coupled resonators with ultrahigh sensitivity
Zhao, Chun; Wood, Graham; Xie, J.B. et al

in Sensors and Actuators. A, Physical (2015), 232

A proof-of-concept force sensor based on three degree-of-freedom (DoF) weakly coupled resonatorswas fabricated using a silicon-on-insulator (SOI) process and electrically tested in 20 Torr vacuum.Compared ... [more ▼]

A proof-of-concept force sensor based on three degree-of-freedom (DoF) weakly coupled resonatorswas fabricated using a silicon-on-insulator (SOI) process and electrically tested in 20 Torr vacuum.Compared to the conventional single resonator force sensor with frequency shift as output, by measuringthe amplitude ratio of two of the three resonators, the measured force sensitivity of the 3DoF sensor was4.9 × 106/N, which was improved by two orders magnitude. A bias stiffness perturbation was applied toavoid mode aliasing effect and improve the linearity of the sensor. The noise floor of the amplitude ratiooutput of the sensor was theoretically analyzed for the first time, using the transfer function model ofthe 3DoF weakly coupled resonator system. It was shown based on measurement results that the outputnoise was mainly due to the thermal–electrical noise of the interface electronics. The output noise spectraldensity was measured, and agreed well with theoretical estimations. The noise floor of the force sensoroutput was estimated to be approximately 1.39nN for an assumed 10 Hz bandwidth of the output signal,resulting in a dynamic range of 74.8 dB. [less ▲]

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See detailImpact of ηEarth on the Capabilities of Affordable Space Missions to Detect Biosignatures on Extrasolar Planets
Léger, Alain; Defrère, Denis; Malbet, Fabien et al

in Astrophysical Journal (2015), 808

We present an analytic model to estimate the capabilities of space missions dedicated to the search for biosignatures in the atmosphere of rocky planets located in the habitable zone of nearby stars ... [more ▼]

We present an analytic model to estimate the capabilities of space missions dedicated to the search for biosignatures in the atmosphere of rocky planets located in the habitable zone of nearby stars. Relations between performance and mission parameters, such as mirror diameter, distance to targets, and radius of planets, are obtained. Two types of instruments are considered: coronagraphs observing in the visible, and nulling interferometers in the thermal infrared. Missions considered are: single-pupil coronagraphs with a 2.4 m primary mirror, and formation-flying interferometers with 4 × 0.75 m collecting mirrors. The numbers of accessible planets are calculated as a function of η[SUB]Earth[/SUB]. When Kepler gives its final estimation for η[SUB]Earth[/SUB], the model will permit a precise assessment of the potential of each instrument. Based on current estimations, η[SUB]Earth[/SUB] = 10% around FGK stars and 50% around M stars, the coronagraph could study in spectroscopy only ∼1.5 relevant planets, and the interferometer ∼14.0. These numbers are obtained under the major hypothesis that the exozodiacal light around the target stars is low enough for each instrument. In both cases, a prior detection of planets is assumed and a target list established. For the long-term future, building both types of spectroscopic instruments, and using them on the same targets, will be the optimal solution because they provide complementary information. But as a first affordable space mission, the interferometer looks the more promising in terms of biosignature harvest. [less ▲]

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See detailA Coordinated X-Ray and Optical Campaign of the Nearest Massive Eclipsing Binary, δ Orionis Aa. IV. A Multiwavelength, Non-LTE Spectroscopic Analysis
Shenar, T.; Oskinova, L.; Hamann, W.-R. et al

in Astrophysical Journal (2015), 809

Eclipsing systems of massive stars allow one to explore the properties of their components in great detail. We perform a multi-wavelength, non-LTE analysis of the three components of the massive multiple ... [more ▼]

Eclipsing systems of massive stars allow one to explore the properties of their components in great detail. We perform a multi-wavelength, non-LTE analysis of the three components of the massive multiple system δ Ori A, focusing on the fundamental stellar properties, stellar winds, and X-ray characteristics of the system. The primary’s distance-independent parameters turn out to be characteristic for its spectral type (O9.5 II), but usage of the Hipparcos parallax yields surprisingly low values for the mass, radius, and luminosity. Consistent values follow only if δ Ori lies at about twice the Hipparcos distance, in the vicinity of the σ-Orionis cluster. The primary and tertiary dominate the spectrum and leave the secondary only marginally detectable. We estimate the V-band magnitude difference between primary and secondary to be {{Δ }}V≈ 2\buildrel{{m}}\over{.} 8. The inferred parameters suggest that the secondary is an early B-type dwarf (≈B1 V), while the tertiary is an early B-type subgiant (≈B0 IV). We find evidence for rapid turbulent velocities (∼200 km s[SUP]‑1[/SUP]) and wind inhomogeneities, partially optically thick, in the primary’s wind. The bulk of the X-ray emission likely emerges from the primary’s stellar wind ({log}{L}[SUB]{{X[/SUB]}}/{L}[SUB]{Bol[/SUB]}≈ -6.85), initiating close to the stellar surface at {R}[SUB]0[/SUB]∼ 1.1 {R}[SUB]*[/SUB]. Accounting for clumping, the mass-loss rate of the primary is found to be {log}\dot{M}≈ -6.4 ({M}[SUB]ȯ [/SUB] {{yr}}[SUP]-1[/SUP]), which agrees with hydrodynamic predictions, and provides a consistent picture along the X-ray, UV, optical, and radio spectral domains. [less ▲]

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See detailDisease Severity Estimates – Effects of Rater Accuracy and Assessment Methods for Comparing Treatments
Bock, Clive; El Jarroudi, Moussa ULg; Kouadio, Louis et al

in Plant Disease (2015), 99(1104-1112),

Assessment of disease severity is required for several purposes in plant pathology; most often the estimates are made visually. It is established that visual estimates can be inaccurate and unreliable ... [more ▼]

Assessment of disease severity is required for several purposes in plant pathology; most often the estimates are made visually. It is established that visual estimates can be inaccurate and unreliable. The ramifications of biased or imprecise estimates by raters have not been fully explored using empirical data; partly because of the logistical difficulties involved in different raters assessing the same leaves for which actual disease has been measured in a replicated experiment with multiple treatments. In this study nearest percent estimates (NPEs) of Septoria leaf blotch (SLB) on leaves of winter wheat from non-treated and fungicide treated plots were assessed in both 2006 and 2007 by four raters and compared to assumed true values measured using image analysis. Lin’s concordance correlation (LCC, ρc) was used to assess agreement between the two approaches. NPEs were converted to Horsfall-Barratt (HB) mid-points and again compared for agreement with true values. The estimates of SLB severity from fungicide-treated and non-treated plots were analyzed using generalized linear mixed modeling to ascertain effects of rater using both the NPE and HB values. Rater 1 showed good agreement with image analysis (ρc = 0.986 to 0.999), while raters 3 and 4 had less good agreement (ρc = 0.205 to 0.936). Conversion to the HB scale had little effect on bias or accuracy, but reduced both precision and agreement for most raters on most assessment dates (precision, r = -0.001 to -0.132; and agreement, ρc = -0.003 to -0.468). Inter-rater reliability was also reduced slightly by conversion of estimates to HB midpoint values. Estimates of mean SLB severity were significantly different between image analysis and raters 2, 3 and 4, and there were frequently significant differences among raters (F=151 to 1260, P=0.001 to <0.0001). Conversion to the HB scale changed the means separation ranking of rater estimates on 26 June 2007. Nonetheless, image analysis and all raters were able to differentiate control and treated plots treatments (F=116 to 1952, P=0.002 to <0.0001, depending on date and rater). Conversion of NPEs to the HB scale tended to reduce F-values slightly (2006: NPEs, F=116 to 276, P=0.002 to 0.0005, and for the HB converted values F=101 to 270, P=0.002 to 0.0005, and in 2007, NPEs, F=164 to 1952 P=0.001 to <0.0001, and for HB converted values F=126 to 1633 P=0.002 to <0.0001). The results demonstrated the need for accurate and reliable disease assessment to minimize over or underestimates compared to actual disease, and where multiple raters are deployed, they should be assigned in a manner to reduce any potential effect of rater differences on the analysis. [less ▲]

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See detailA Coordinated X-Ray and Optical Campaign of the Nearest Massive Eclipsing Binary, δ Orionis Aa. III. Analysis of Optical Photometric (MOST) and Spectroscopic (Ground-based) Variations
Pablo, Herbert; Richardson, Noel D.; Moffat, Anthony F. J. et al

in Astrophysical Journa (2015), 809

We report on both high-precision photometry from the Microvariability and Oscillations of Stars (MOST) space telescope and ground-based spectroscopy of the triple system δ Ori A, consisting of a binary O9 ... [more ▼]

We report on both high-precision photometry from the Microvariability and Oscillations of Stars (MOST) space telescope and ground-based spectroscopy of the triple system δ Ori A, consisting of a binary O9.5II+early-B (Aa1 and Aa2) with P = 5.7 days, and a more distant tertiary (O9 IV P\gt 400 years). This data was collected in concert with X-ray spectroscopy from the Chandra X-ray Observatory. Thanks to continuous coverage for three weeks, the MOST light curve reveals clear eclipses between Aa1 and Aa2 for the first time in non-phased data. From the spectroscopy, we have a well-constrained radial velocity (RV) curve of Aa1. While we are unable to recover RV variations of the secondary star, we are able to constrain several fundamental parameters of this system and determine an approximate mass of the primary using apsidal motion. We also detected second order modulations at 12 separate frequencies with spacings indicative of tidally influenced oscillations. These spacings have never been seen in a massive binary, making this system one of only a handful of such binaries that show evidence for tidally induced pulsations. [less ▲]

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See detailPerformance et expérience esthétique : le régime contemporain (Rancière)
Hagelstein, Maud ULg

in Revue Philosophique de Louvain (2015), 113(3), 479-495

The theory of regimes of identification of art set up by the philosopher J. Rancière describes the transition from the former system of Fine Arts to the aesthetic regime of art. According to this ... [more ▼]

The theory of regimes of identification of art set up by the philosopher J. Rancière describes the transition from the former system of Fine Arts to the aesthetic regime of art. According to this contemporary regime the characteristic of the various arts no longer depends essentially on their technical skill (poiesis), but on the sensible experience they favour independently of their specific ways of doing things. Artistic performance fits in perfectly into this aesthetic regime of art having regard to its ideological project: (1) it aims at the enlargement of sense experience (aesthetic experience) beyond the mere production of an object, thus destabilising the frontiers between the artistic and the non-artistic; (2) it seeks to restore the links between art and ordinary experience in order to favour living art. We shall show that the ideas developed by the Anglo-Saxon pragmatist philosophy J. Dewey strongly contributed to the definition of this radical artistic project (transl. J. Dudley). [less ▲]

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See detailPerformance, robustness and sensitivity analysis of the nonlinear tuned vibration absorber
Detroux, Thibaut ULg; Habib, Giuseppe ULg; Masset, Luc ULg et al

in Mechanical Systems & Signal Processing (2015), 60-61

The nonlinear tuned vibration absorber (NLTVA) is a recently developed nonlinear absorber which generalizes Den Hartog׳s equal peak method to nonlinear systems. If the purposeful introduction of ... [more ▼]

The nonlinear tuned vibration absorber (NLTVA) is a recently developed nonlinear absorber which generalizes Den Hartog׳s equal peak method to nonlinear systems. If the purposeful introduction of nonlinearity can enhance system performance, it can also give rise to adverse dynamical phenomena, including detached resonance curves and quasiperiodic regimes of motion. Through the combination of numerical continuation of periodic solutions, bifurcation detection and tracking, and global analysis, the present study identifies boundaries in the NLTVA parameter space delimiting safe, unsafe and unacceptable operations. The sensitivity of these boundaries to uncertainty in the NLTVA parameters is also investigated. [less ▲]

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See detailUse of specklegrams background terms for speckle photography combined with phase-shifting electronic speckle pattern interferometry
Zemmamouche, Redouane; Vandenrijt, Jean-François ULg; Medjahed, Aïcha et al

in Optical Engineering : The Journal of the Society of Photo-Optical Instrumentation Engineers (2015), 54(8), 084110

Electronic speckle pattern interferometry (ESPI) is combined with digital speckle photography (DSP) to measure out-of-plane deformation in the presence of large in-plane translation or rotation. ESPI is ... [more ▼]

Electronic speckle pattern interferometry (ESPI) is combined with digital speckle photography (DSP) to measure out-of-plane deformation in the presence of large in-plane translation or rotation. ESPI is used to measure out-of-plane displacements smaller than the speckle diameter. In-plane displacements larger than the speckle size are obtained by DSP using artifacts images computed from the phase-stepped specklegrams. Previous works use the specklegram modulation for that purpose, but we show that this can lead to errors in the case of low modulation. In order to avoid this, a simple averaging of phase-stepped specklegrams allows obtaining the average irradiance, which contains information on the speckled object image. The latter can be used more efficiently than the modulation in DSP and is simpler to compute. We also perform a numerical simulation of specklegrams, which show that the use of background terms is much more stable against some error sources as compared to modulation. We show experimental evidence of this in various experiments combining out-of-plane ESPI measurements with in-plane translations or rotations obtained by our DSP method. The latter has been used efficiently to restore phase loss in out-of-plane ESPI measurements due to large in-plane displacements. [less ▲]

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See detailPharmacists' role in handling problems with prescriptions for atithrombotic medication in Belgian community pharmacies
Desmaele; De Wulf, I; Dupont, AG et al

in International Journal of Clinical Pharmacy [=IJCP] (2015), 37(4), 656-668

Background Community pharmacists have an important task in the follow-up of patients treated with antithrombotics. When delivering these medicines, pharmacists can encounter drug–related problems (DRPs ... [more ▼]

Background Community pharmacists have an important task in the follow-up of patients treated with antithrombotics. When delivering these medicines, pharmacists can encounter drug–related problems (DRPs) with substantial clinical and economic impact. Objective To investigate the amount and type of antithrombotic related DRPs as well as how community pharmacists handled these DRPs. Setting Belgian community pharmacies. Methods MSc pharmacy students of six Belgian universities collected data about all DRPs encountered by a pharmacist during ten half days of their pharmacy internship. Data were registered about DRPs detected at delivery and in an a posteriori setting, when consulting the medical history of the patient. Classification of the DRP, cause of the DRP, intervention and result of the intervention were registered. Main outcome measure Amount and type of antotrombitocs related DRPs occurring in community pharmacies, as well as how community pharmacists handled these DRPs. Results 3.1 % of the 15,952 registered DRPs concerned antithrombotics. 79.3 % of these DRPs were detected at delivery and 20.7 % were detected a posteriori. Most antithrombotic-related DRPs concerned problems with the choice of the drug (mainly because of drug–drug interactions) or concerned logistic problems. Almost 80 % of the antithrombotic-related DRPs were followed by an intervention of the pharmacist, mainly at the patient’s level, resulting in 90.1 % of these DRPs partially or totally solved. Conclusion Different DRPs with antithrombotic medication occurred in Belgian community pharmacies. About 20 % was detected in an a posteriori setting, showing the benefit of medication review. Many of the encountered DRPs were of technical nature (60.7 %). These DRPs were time-consuming for the pharmacist to resolve and should be prevented. Most of the DRPs could be solved, demonstrating the added value of the community pharmacist as first line healthcare provider. [less ▲]

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See detailInfluence of rhizobacterial volatiles on the root system architecture and the production and allocation of biomass in the model grass Brachypodium distachyon (L.) P. Beauv.
Delaplace, Pierre ULg; Delory, Benjamin ULg; Baudson, Caroline ULg et al

in BMC Plant Biology (2015), 15(195),

Background Plant growth-promoting rhizobacteria are increasingly being seen as a way of complementing conventional inputs in agricultural systems. The effects on their host plants are diverse and include ... [more ▼]

Background Plant growth-promoting rhizobacteria are increasingly being seen as a way of complementing conventional inputs in agricultural systems. The effects on their host plants are diverse and include volatile-mediated growth enhancement. This study sought to assess the effects of bacterial volatiles on the biomass production and root system architecture of the model grass Brachypodium distachyon (L.) Beauv. Results An in vitro experiment allowing plant-bacteria interaction throughout the gaseous phase without any physical contact was used to screen 19 bacterial strains for their growth-promotion ability over a 10-day co-cultivation period. Five groups of bacteria were defined and characterised based on their combined influence on biomass production and root system architecture. The observed effects ranged from unchanged to greatly increased biomass production coupled with increased root length and branching. Primary root length was increased only by the volatile compounds emitted by Enterobacter cloacae JM22 and Bacillus pumilus T4. Overall, the most significant results were obtained with Bacillus subtilis GB03, which induced an 81% increase in total biomass, as well as enhancing total root length, total secondary root length and total adventitious root length by 88.5, 201.5 and 474.5%, respectively. Conclusions This study is the first report on bacterial volatile-mediated growth promotion of a grass plant. Contrasting modulations of biomass production coupled with changes in root system architecture were observed. Most of the strains that increased total plant biomass also modulated adventitious root growth. Under our screening conditions, total biomass production was strongly correlated with the length and branching of the root system components, except for primary root length. An analysis of the emission kinetics of the bacterial volatile compounds is being undertaken and should lead to the identification of the compounds responsible for the observed growth-promotion effects. Within the context of the inherent characteristics of our in vitro system, this paper identifies the next critical experimental steps and discusses them from both a fundamental and an applied perspective. [less ▲]

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See detailAtypical plasma cells with coexpression of myeloid markers and bundles of Auer rod-like inclusions.
KEUTGENS, Aurore ULg; FOGUENNE, Jacques ULg; Gothot, André ULg et al

in International journal of laboratory hematology (2015), 37(4), 85-6

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See detailVitamin D status after a high dose of cholecalciferol in healthy and burn subjects
ROUSSEAU, Anne-Françoise ULg; DAMAS, Pierre ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (2015), 41(5), 1028-1034

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a ... [more ▼]

Background: Burn patients are at risk of vitamin D (VD) deficiency and may benefit from its pleiotropic effects as soon as acute phase. Aim of this observational study was to assess effects of a cholecalciferol (VD3) bolus on VD status in adult burn patients (Group B, GB) after admission, compared to healthy subjects (Group H, GH). Methods: Both groups received an oral dose of 100,000 IU VD3. Blood samples were collected before (D0) and 7 days (D7) after bolus to measure 250H-D, 1,25(OH)2-D, parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). Albumin (ALB) and VD binding protein (DBP) were measured and used to calculate free 25OH-D level. Data were expressed as median (min–max) or proportions. Results: A total of 49 subjects were included: 29 in GH and 20 in GB. At D0, prevalence of VD deficiency was higher in GB: 25OH-D was 21.5 (10.1–46.3) ng/ml in GH vs 11 (1.8–31.4) ng/ml in GB. DBP and ALB were lower in GB. At D7, DBP was stable in both groups while ALB decreased in GB. 25OH-D increased by 66.6 (13.5–260.3)% in GH. In GB, changes in 25OH-D extended from 36.7% to 333.3% with a median increase of 33.1%. Similar changes were observed in each group for free 25OH-D. High FGF23 levels were observed in GB. Conclusions: This study highlighted the differences in VD status and in response to a high dose VD3 in burn patients when compared to healthy patients. Pitfalls in VD status assessment are numerous during acute burn care: 25OH-D measurement needs cautious interpretation and interest of free 25OH-D is still questionable. They should not prevent burn patients to receive VD supplements during acute care. Higher doses than general recommendations should probably be considered. [less ▲]

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See detailThe Brussels Court judgement in Commission v Elevators manufacturers, or the story of how the Commission lost an action for damages based on its own infringement decision.
Marcos Ramos, Jorge ULg; Muheme, Daniel ULg

in European Competition Law Review (2015), 36(9),

With the proceedings before the Brussels Court, the Commission emphasized its growing need to promote claims for damages for infringements of EU Competition law. Ahead of the implementation of the Damages ... [more ▼]

With the proceedings before the Brussels Court, the Commission emphasized its growing need to promote claims for damages for infringements of EU Competition law. Ahead of the implementation of the Damages Directive, and with its own infringement decision in hand, this claim seemed to be an easy exercise for the Commission to recoup the allegedly surplus paid for the maintenance contracts. [less ▲]

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See detailA study of composite laminates failure using an anisotropic gradient-enhanced damage mean-field homogenization model
Wu, Ling ULg; Sket, Federico; Molina-Aldareguia, Jon M et al

in Composite Structures (2015), 126

The failure of carbon fiber reinforced epoxy laminates is studied using an anisotropic gradient-enhanced continuum damage model embedded in a mean-field homogenization scheme. In each ply, a homogenized ... [more ▼]

The failure of carbon fiber reinforced epoxy laminates is studied using an anisotropic gradient-enhanced continuum damage model embedded in a mean-field homogenization scheme. In each ply, a homogenized material law is used to capture the intra-laminar failure. The anisotropy of the homogenized material model results from the homogenization method and from the reformulation of the non-local continuum damage theory to account for the material anisotropy. As a result the damage propagation direction in each ply is predicted with accuracy as compared to the experimental results, while the problems of losing uniqueness and strain localization, which occur in classical finite element simulations when strain softening of materials is involved, can be avoided. To model the delamination process, the hybrid discontinuous Galerkin/extrinsic cohesive law method is introduced at the ply interfaces. This hybrid method avoids the need to propagate topological changes in the mesh with the propagation of the delamination while it preserves the consistency and stability in the un-cracked interfaces. As a demonstration, open-hole coupons with different stacking sequences are studied numerically and experimentally. Both the intra- and inter-laminar failure patterns are shown to be well captured by the computational framework. [less ▲]

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See detailCharacterizing activity sequences using Profile Hidden Markov Models
Liu, Feng; Janssens, Davy; Cui, JianXun et al

in Expert Systems with Applications (2015), 42(13), 57055722

In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment ... [more ▼]

In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment Methods (SAM). However, using these methods, only the frequent activities in each cluster are extracted and qualitatively described; the infrequent activities and their related travel episodes are disregarded. Thus, to quantify the occurrence probabilities of all the daily activities as well as their sequential orders, we develop a novel process to build multiple alignments of the sequences and subsequently derive profile Hidden Markov Models (pHMMs). This process consists of 4 major steps. First, activity sequences are clustered based on a pre-defined scheme. The frequent activities along with their sequential orders are then identified in each cluster, and they are subsequently used as a template to guide the construction of a multiple alignment of the cluster of sequences. Finally, a pHMM is employed to convert the multiple alignment into a position-specific scoring system, representing the probability of each frequent activity at each important position of the alignment as well as the probabilities of both insertion and deletion of infrequent activities. By applying the derived pHMMs to a set of activity-travel diaries collected in Belgium as well as a group of mobile phone call location data recorded in Switzerland, the potential and effectiveness of the models in capturing the sequential features of each cluster and distinguishing them from those of other clusters, are demonstrated. The proposed method can also be utilized to improve activity-based transportation model validation and travel survey designs. Furthermore, it offers a wide application in characterizing a group of any related sequences, particularly sequences varying in length and with a high frequency of short sequences that are typically present in human behavior. [less ▲]

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See detailL’action du FDF dans les Régions et Communautés (1971-2014). II. Institutions bruxelloises
Lanneau, Catherine ULg

in Courrier Hebdomadaire du CRISP (2015), (2260-2261), 61

Depuis sa création, le FDF poursuit un triple objectif au plan institutionnel : assurer la solidarité entre Wallons et Bruxellois francophones, garantir les droits linguistiques des francophones de ... [more ▼]

Depuis sa création, le FDF poursuit un triple objectif au plan institutionnel : assurer la solidarité entre Wallons et Bruxellois francophones, garantir les droits linguistiques des francophones de Flandre (en particulier dans la périphérie) et bâtir une Région bruxelloise forte (avec si possible un territoire élargi). Pour promouvoir ses idées, le FDF a porté son combat non seulement sur le terrain communal et national, mais également dans les Régions et les Communautés. Le présent Courrier hebdomadaire retrace les principales lignes de force de l’action du FDF dans les organes des entités fédérées où il a été présent au cours des cinquante dernières années : le Parlement de la Communauté française, le Parlement flamand et les institutions bruxelloises. Quel rôle le FDF a-t-il joué à la Communauté française ? Quelle a été l’action de son député au Parlement flamand ? Comment s’est articulée la lutte du parti pour l’institutionnalisation d’une Région bruxelloise et, une fois celle-ci créée en 1989, dans quelle mesure y a-t-il appliqué son programme ? Le FDF a-t-il réussi à dépasser son image de parti focalisé sur les thématiques linguistiques pour se positionner en mouvement « urbain et culturel » se définissant comme « réformateur social » ? L’attention se porte sur la pratique du parti tant agissant seul qu’évoluant en partenariat avec le Rassemblement wallon ou, plus récemment, avec les libéraux. [less ▲]

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See detailDigestibility of solvent-treated Jatropha curcas kernel by broiler chickens in Senegal
Nesseim, Thierry Daniel Tamsir; Dieng, Abdoulaye; Mergeai, Guy ULg et al

in Tropical Animal Health and Production (2015)

Jatropha curcas is a drought-resistant shrub belonging to the Euphorbiaceae family. The kernel contains approximately 60 % lipid in dry matter, and the meal obtained after oil extraction could be an ... [more ▼]

Jatropha curcas is a drought-resistant shrub belonging to the Euphorbiaceae family. The kernel contains approximately 60 % lipid in dry matter, and the meal obtained after oil extraction could be an exceptional source of protein for family poultry farming, in the absence of curcin and, especially, some diterpene derivatives phorbol esters that are partially lipophilic. The nutrient digestibility of J. curcas kernel meal (JKM), obtained after partial physicochemical deoiling was thus evaluated in broiler chickens. Twenty broiler chickens, 6 weeks old, were maintained in individual metabolic cages and divided into four groups of five animals, according to a 4 × 4 Latin square design where deoiled JKM was incorporated into grinded corn at 0, 4, 8, and 12 % levels (diets 0, 4, 8, and 12 J), allowing measurement of nutrient digestibility by the differential method. The dry matter (DM) and organic matter (OM) digestibility of diets was affected to a low extent by JKM (85 and 86 % in 0 J and 81 % in 12 J, respectively) in such a way that DM and OM digestibility of JKM was estimated to be close to 50 %. The ether extract (EE) digestibility of JKM remained high, at about 90 %, while crude protein (CP) and crude fiber (CF) digestibility were largely impacted by JKM, with values closed to 40 % at the highest levels of incorporation. J. curcas kernel presents various nutrient digestibilities but has adverse effects on CP and CF digestibility of the diet. The effects of an additional heat or biological treatment on JKM remain to be assessed. [less ▲]

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See detailL’action du FDF dans les Régions et Communautés (1971-2014). I. Le Parlement de la Communauté française et le Parlement flamand
Lanneau, Catherine ULg

in Courrier Hebdomadaire du CRISP (2015), (2258-2259), 60

Depuis sa création, le FDF poursuit un triple objectif au plan institutionnel : assurer la solidarité entre Wallons et Bruxellois francophones, garantir les droits linguistiques des francophones de ... [more ▼]

Depuis sa création, le FDF poursuit un triple objectif au plan institutionnel : assurer la solidarité entre Wallons et Bruxellois francophones, garantir les droits linguistiques des francophones de Flandre (en particulier dans la périphérie) et bâtir une Région bruxelloise forte (avec si possible un territoire élargi). Pour promouvoir ses idées, le FDF a porté son combat non seulement sur le terrain communal et national, mais également dans les Régions et les Communautés. Le présent Courrier hebdomadaire retrace les principales lignes de force de l’action du FDF dans les organes des entités fédérées où il a été présent au cours des cinquante dernières années : le Parlement de la Communauté française, le Parlement flamand et les institutions bruxelloises. Quel rôle le FDF a-t-il joué à la Communauté française ? Quelle a été l’action de son député au Parlement flamand ? Comment s’est articulée la lutte du parti pour l’institutionnalisation d’une Région bruxelloise et, une fois celle-ci créée en 1989, dans quelle mesure y a-t-il appliqué son programme ? Le FDF a-t-il réussi à dépasser son image de parti focalisé sur les thématiques linguistiques pour se positionner en mouvement « urbain et culturel » se définissant comme « réformateur social » ? L’attention se porte sur la pratique du parti tant agissant seul qu’évoluant en partenariat avec le Rassemblement wallon ou, plus récemment, avec les libéraux. [less ▲]

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See detailFish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries
Castano, Argelia; Cutanda, Francisco; Esteban, Marta et al

in Environmental Research (2015), 141

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential ... [more ▼]

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-​levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-​child pairs from 17 European countries using a strictly harmonized protocol for mercury anal. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster anal. of consumption habits of the mother-​child pairs, the DEMOCOPHES cohort can be classified into two branches of approx. similar size: one with high fish consumption (H) and another with low consumption (L)​. All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-​child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concn. between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-​child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish contribute significantly to the mercury levels in hair. We conclude that addnl. studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster anal. also showed that 95​% of mothers who consume once per wk fish only, and no other marine products, have mercury levels 0.55 μg​/g. Thus, the 95th percentile of the distribution in this group is only around half the US-​EPA recommended threshold of 1 μg​/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an addnl. dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements. [less ▲]

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See detailOpérations militaires : entre prise de risque, solidarité, souveraineté et "entrée en premier"
Dumoulin, André ULg

in Sécurité & Stratégie (2015), (201),

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See detailRupture post-traumatique de l’isthme aortique : perspectives modernes de prise en charge
BRULS, Samuel ULg; GOFFIN, Pierre ULg; Sakalihasan, Natzi ULg et al

in Revue Médicale de Liège (2015), 70(9), 415-22

Traumatic aortic rupture of the thoracic aorta (usually at the isthmus) is frequently associated with concomitant life-threatening injuries. Historically, the conventional care consisted of surgical ... [more ▼]

Traumatic aortic rupture of the thoracic aorta (usually at the isthmus) is frequently associated with concomitant life-threatening injuries. Historically, the conventional care consisted of surgical repair of the lesion performed as soon as possible. However, in spite of constant technical improvements the morbi-mortality remains high because of these associated lesions. In addition, their management can have priority and delay aortic surgery. The endovascular approach has been shown to be a feasible and efficient technique and currently represents a valuable alternative to open surgery for patients with multiple traumas. We report a patient presenting with a traumatic aortic rupture of the aortic isthmus, which was successfully treated by delayed combined endovascular (thoracic aortic stentgrafting) and open approach (hemi-aortic arch debranching). [less ▲]

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See detailUse of Tomosynthesis for Detection of Bone Erosions of the Foot in Patients With Established Rheumatoid Arthritis: Comparison With Radiography and CT.
SIMONI, Paolo ULg; Gerard, Lionel ULg; KAISER, Marie-Joëlle ULg et al

in American Journal of Roentgenology (2015), (205), 364-370

The purpose of this study was to compare tomosynthesis with radiography for the detection of bone erosions of the foot in patients with established rheumatoid arthritis (RA) using MDCT as a reference ... [more ▼]

The purpose of this study was to compare tomosynthesis with radiography for the detection of bone erosions of the foot in patients with established rheumatoid arthritis (RA) using MDCT as a reference standard. [less ▲]

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See detailLe Parc National Sahamalaza - Iles Radama serait-il l’ultime refuge pour certaines espèces de lémuriens du nord-ouest de Madagascar ?
Wilmet, Leslie ULg; Beudels-Jamar, Roseline C.; Schwitzer, Christoph et al

in Tropicultura (2015)

Depuis des millions d’années, la faune et la flore terrestre de Madagascar ont évolué dans un espace isolé. Suite à cette situation, le niveau d’endémisme y est très élevé et l’ensemble de l’île ... [more ▼]

Depuis des millions d’années, la faune et la flore terrestre de Madagascar ont évolué dans un espace isolé. Suite à cette situation, le niveau d’endémisme y est très élevé et l’ensemble de l’île représente un des plus importants hotspot de biodiversité. Madagascar fait aussi partie des pays les plus touchés en termes de destruction des habitats naturels ; 90 % de la végétation d’origine est aujourd’hui perdue. La déforestation et la fragmentation des habitats forestiers menace particulièrement les primates de l’île, les lémuriens. L’île est considérée par de nombreuses organisations internationales comme une priorité pour la conservation de la nature, autant dans le domaine zoologique que botanique. Les premières aires protégées de Madagascar ont été établies en 1927 et l’île en compte aujourd’hui 47. Cet article reprend l’historique et fait l’état des lieux du parc national Sahamalaza-Ile Radama, situé au nord-ouest de Madagascar. Nous nous intéressons spécifiquement à deux espèces de lémuriens emblématiques du parc ; Eulemur flavifrons et Lepilemur sahamalazensis ainsi qu’aux menaces qui pèsent sur leur écosystème. Différentes mesures ont été proposées dans le cadre d’un Plan d’Action de Conservation afin d’en améliorer la gestion et assurer la survie de ces espèces. [less ▲]

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See detailShort-term responses of glass eels transported from UK to small Belgian streams
Ovidio, Michaël ULg; Tarrago-Bes, Frédérique; Nzau Matondo, Billy ULg

in Annales de Limnologie = International Journal of Limnology (2015), 51(3), 219-226

Restocking of inland waters with glass eels is one of the recovery options to prevent the decline of European eel Anguilla anguilla (L.) populations. We studied the growth, dispersion, density and habitat ... [more ▼]

Restocking of inland waters with glass eels is one of the recovery options to prevent the decline of European eel Anguilla anguilla (L.) populations. We studied the growth, dispersion, density and habitat preferences in the imported glass eels from United-Kingdom and stocked in three typologically different small Belgian streams, using electrofishing surveys around the single release point, 1 year following stocking. Our results clearly support that the recaptured individuals stocked in our streams farther from the sea, survived, grew, dispersed upstream and downstream. Elvers exploited the complete transversal section of stream, with preference for the sheltered microhabitats near the banks with slower water velocity and low depth. Length-weight relationship was different between streams in terms of allometric coefficient (b). We assume that microhabitats and food availabilities lead to contrasted results in terms of growth and absolute occurrence. Restocking of glass eels in small middle-land streams was found to be an interesting and unconventional option that requires adequate stream and habitat selection. [less ▲]

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See detailChallenges for Scale-Up of Batch Separations
Pfennig, Andreas ULg; Becker, Karsten; Bach, S. et al

in Chemie Ingenieur Technik (2015), 87(8), 1051

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See detailp-regularity of the p-adic valuation of the Fibonacci sequence
Medina, Luis; Rowland, Eric ULg

in Fibonacci Quarterly (The) (2015), 53(3), 265-271

We show that the p-adic valuation of the sequence of Fibonacci numbers is a p-regular sequence for every prime p. For p≠2,5, we determine that the rank of this sequence is α(p)+1, where α(m) is the ... [more ▼]

We show that the p-adic valuation of the sequence of Fibonacci numbers is a p-regular sequence for every prime p. For p≠2,5, we determine that the rank of this sequence is α(p)+1, where α(m) is the restricted period length of the Fibonacci sequence modulo m. [less ▲]

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See detailQuand le progrès doit rester humain
RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète (2015), 58

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See detailOptimization of composite structures with curved fiber trajectories
Lemaire, Etienne; Zein, Samih; Bruyneel, Michaël ULg

in Composite Structures (2015), 131

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See detailElectrical characterization of p-GeSn/n-Ge diodes with interface traps under dc and ac regimes
Baert, Bruno ULg; Gupta, Somya; Gencarelli, Federica et al

in Solid-State Electronics (2015), 110

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See detailDesign, Modeling, and Performance Optimization of a Reversible Heat Pump/Organic Rankine Cycle System for Domestic Application
Quoilin, Sylvain ULg; Dumont, Olivier ULg; Harley Hansen, Kristian et al

in Journal of Engineering for Gas Turbines and Power (2015)

In this paper, an innovative system combining a heat pump (HP) and an organic Rankine cycle (ORC) process is proposed. This system is integrated with a solar roof, which is used as a thermal source to ... [more ▼]

In this paper, an innovative system combining a heat pump (HP) and an organic Rankine cycle (ORC) process is proposed. This system is integrated with a solar roof, which is used as a thermal source to provide heat in winter months (HP mode) and electricity in summer months (ORC mode) when an excess irradiation is available on the solar roof. The main advantage of the proposed unit is its similarity with a traditional HP: the HP/ORC unit only requires the addition of a pump and four-way valves compared to a simple HP, which can be achieved at a low cost. A methodology for the optimal sizing and design of the system is proposed, based on the optimization of both continuous parameters such as heat exchanger size or discrete variables such as working fluid. The methodology is based on yearly simulations, aimed at optimizing the system performance (the net yearly power generation) over its whole operating range instead of just nominal sizing operating conditions. The simulations allow evaluating the amount of thermal energy and electricity generated throughout the year, yielding a net electric power output of 3496 kWh throughout the year. [less ▲]

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See detailChemical spying in coral reef fish larvae at recruitment
Roux, Natacha; Brooker, Rohan M.; Lecellier, Gaël et al

in Comptes Rendus Biologies (2015), 338

When fish larvae recruit back to a reef, chemical cues are often used to find suitable habitat or to find juvenile or adult conspecifics. We tested if the chemical information used by larvae was ... [more ▼]

When fish larvae recruit back to a reef, chemical cues are often used to find suitable habitat or to find juvenile or adult conspecifics. We tested if the chemical information used by larvae was intentionally produced by juvenile and adult conspecifics already on the reef (communication process) or whether the cues used result from normal biochemical processes with no active involvement by conspecifics (‘‘spying’’ behavior by larvae). Conspecific chemical cues attracted the majority of larvae (four out of the seven species tested); although while some species were equally attracted to cues from adults and juveniles (Chromis viridis, Apogon novemfasciatus), two exhibited greater sensitivity to adult cues (Pomacentrus pavo, Dascyllus aruanus). Our results indicate also that spying cues are those most commonly used by settling fishes (C. viridis, P. pavo, A. novemfasciatus). Only one species (D. aruanus) preferred the odour of conspecifics that had had visual contact with larvae (communication). [less ▲]

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See detailLe monopole de la légitimité démocratique
Debras, François ULg

in Revue de la Faculté de Droit de l'Université de Liège (2015), 2

Loin d’être le résultat de facteurs externes, la contestation du régime démocratique semble être avant tout le résultat d’une critique inhérente au système. Différents indicateurs mesurables viennent ... [more ▼]

Loin d’être le résultat de facteurs externes, la contestation du régime démocratique semble être avant tout le résultat d’une critique inhérente au système. Différents indicateurs mesurables viennent étayer ce que certains auteurs qualifient de « syndrome de fatigue démocratique » ou encore de « corruption du régime constitutionnel pluraliste », tels que l’augmentation de l’abstentionnisme durant les périodes électorales, une volatilité et une instabilité croissante de l’électorat et une baisse des adhésions aux organisations collectives. Fait tout aussi significatif, il semblerait que les jeunes démocraties dans les pays de l’ex-Union soviétique, d’Asie ou d’Amérique latine n’échappent pas non plus à ces phénomènes. Cette situation illustre-t-elle une perte de légitimité démocratique, une crise démocratique ou ne correspond-elle pas plutôt à une volonté citoyenne de transformer nos démocraties en élargissant et en approfondissant certaines de ses dynamiques et procédures qui lui sont propres ? Pour répondre à cette question, nous proposons de nous concentrer sur trois éléments distincts, mais étroitement liés au sein de nos démocraties européennes au XXIe siècle : le lien représentant/représenté (la représentation), la reconnaissance des libertés individuelles vis-à-vis de l’organisation collective de la société (les citoyens) et l’action du pouvoir étatique (l’État). [less ▲]

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See detailA simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering
De Bleye, Charlotte ULg; Dumont, Elodie ULg; Hubert, Cédric ULg et al

in Analytica Chimica Acta (2015), 888

Bisphenol A (BPA) is well known for its use in plastic manufacture and thermal paper production despite its risk of health toxicity as an endocrine disruptor in humans. Since the publication of new ... [more ▼]

Bisphenol A (BPA) is well known for its use in plastic manufacture and thermal paper production despite its risk of health toxicity as an endocrine disruptor in humans. Since the publication of new legislation regarding the use of BPA, manufacturers have begun to replace BPA with other phenolic molecules such as bisphenol F (BPF) and bisphenol B (BPB), but there are no guarantees regarding the health safety of these compounds at this time. In this context, a very simple, cheap and fast surface-enhanced Raman scattering (SERS) method was developed for the sensitive detection of these molecules in spiked tap water solutions. Silver nanoparticles were used as SERS substrates. An original strategy was employed to circumvent the issue of the affinity of bisphenols for metallic surfaces and the silver nanoparticles surface was functionalized using pyridine in order to improve again the sensitivity of the detection. Semi-quantitative detections were performed in tap water solutions at a concentrations range from 0.25 to 20 µg L-1 for BPA and BPB and from 5 to 100 µg L-1 for BPF. Moreover, a feasibility study for performing a multiplex-SERS detection of these molecules was also performed before successfully implementing the developed SERS method on real samples. [less ▲]

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See detailA Simple Laparoscopic Procedure to Restore a Normal Vaginal Length After Colpohysterectomy With Large Upper Colpectomy for Cervical and/or Vaginal Neoplasia.
Leblanc, Eric; Bresson, L.; Merlot, B. et al

in Journal of Minimally Invasive Gynecology (2015)

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See detailSystematic analysis of site-specific yield distributions resulting from nitrogen management and climatic variability interactions
Dumont, Benjamin ULg; Basso, Bruno; Leemans, Vincent ULg et al

in Precision Agriculture (2015), 16(4), 361-384

At the plot level, crop simulation models such as STICS have the potential to evaluate risk associated with management practices. In nitrogen (N) management, however, the decision-making process is ... [more ▼]

At the plot level, crop simulation models such as STICS have the potential to evaluate risk associated with management practices. In nitrogen (N) management, however, the decision-making process is complex because the decision has to be taken without any knowledge of future weather conditions. The objective of this paper is to present a general methodology for assessing yield variability linked to climatic uncertainty and variable N rate strategies. The STICS model was coupled with the LARS-Weather Generator. The Pearson system and coefficients were used to characterise the shape of yield distribution. Alternatives to classical statistical tests were proposed for assessing the normality of distributions and conducting comparisons (namely, the Jarque-Bera and Wilcoxon tests, respectively). Finally, the focus was put on the probability risk assessment, which remains a key point within the decision process. The simulation results showed that, based on current N application practice among Belgian farmers (60 60 60 kgN ha-1), yield distribution was very highly significantly non normal, with the highest degree of asymmetry characterised by a skewness value of -1.02. They showed that this strategy gave the greatest probability (60%) of achieving yields that were superior to the mean (10.5 t ha-1) of the distribution. [less ▲]

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See detailWhen it is not inflammatory bowel disease: differential diagnosis
Louis, Edouard ULg

in Current Opinion in Gastroenterology (2015)

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See detailPredictions of Daily Milk and Fat Yields, Major Groups of Fatty Acids, and C18:1 cis-9 from Single Milking Data without a Milking Interval
Arnould, Valérie ULg; Reding, Romain; Bormann, Jeanne et al

in Animals (2015), 5(3), 643-661

Reducing the frequency of milk recording would help reduce the costs of official milk recording. However, this approach could also negatively affect the accuracy of predicting daily yields. This problem ... [more ▼]

Reducing the frequency of milk recording would help reduce the costs of official milk recording. However, this approach could also negatively affect the accuracy of predicting daily yields. This problem has been investigated in numerous studies. In addition, published equations take into account milking intervals (MI), and these are often not available and/or are unreliable in practice. The first objective of this study was to propose models in which the MI was replaced by a combination of data easily recorded by dairy farmers. The second objective was to further investigate the fatty acids (FA) present in milk. Equations to predict daily yield from AM or PM data were based on a calibration database containing 79,971 records related to 51 traits [milk yield (expected AM, expected PM, and expected daily); fat content (expected AM, expected PM, and expected daily); fat yield (expected AM, expected PM, and expected daily; g/day); levels of seven different FAs or FA groups (expected AM, expected PM, and expected daily; g/dL milk), and the corresponding FA yields for these seven FA types/groups (expected AM, expected PM, and expected daily; g/day)]. These equations were validated using two distinct external datasets. The results obtained from the proposed models were compared to previously published results for models which included a MI effect. The corresponding correlation values ranged from 96.4% to 97.6% when the daily yields were estimated from the AM milkings and ranged from 96.9% to 98.3% when the daily yields were estimated from the PM milkings. The simplicity of these proposed models should facilitate their use by breeding and milk recording organizations. [less ▲]

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See detailComparison between observed and simulated aeolian snow mass fluxes in Adélie Land, East Antarctica
Amory, Charles; Trouvillez, A.; Gallée, H. et al

in Cryosphere (The) (2015), 9

The regional climate model MAR including a coupled snow pack/aeolian snow transport parameterisation is compared with aeolian snow mass fluxes at a fine spatial resolution (5 km horizontally and 2 m ... [more ▼]

The regional climate model MAR including a coupled snow pack/aeolian snow transport parameterisation is compared with aeolian snow mass fluxes at a fine spatial resolution (5 km horizontally and 2 m vertically) and at a fine temporal resolution (30 min) over 1 month in Antarctica. Numerous feedbacks are taken into account in the MAR including the drag partitioning caused by the roughness elements. Wind speed is correctly simulated with a positive value of the Nash test (0.60 and 0.37) but the wind speeds above 10 m s−1 are underestimated. The aeolian snow transport events are correctly reproduced with a good temporal resolution except for the aeolian snow transport events with a particles' maximum height below 1 m. The simulated threshold friction velocity, calculated without snowfall, is overestimated. The simulated aeolian snow mass fluxes between 0 to 2 m have the same variations but are underestimated compared to the second-generation FlowCapt values and so is the simulated relative humidity at 2 m. This underestimation is not entirely due to the underestimation of the simulated wind speed. The MAR underestimates the aeolian snow quantity that pass through the first two meters by a factor ten compared to the second-generation FlowCapt value (13 990 kg m−1 and 151 509 kg m−1 respectively). It will conduct the MAR, with this parametrisation, to underestimate the effect of the aeolian snow transport on the Antarctic surface mass balance. [less ▲]

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See detailSpeed limit to the Abrikosov lattice in mesoscopic superconductors
Grimaldi, Gaia; Leo, Antonio; Sabatino, P. et al

in Physical Review. B : Condensed Matter (2015), 92

We study the instability of the superconducting state in a mesoscopic geometry for the low pinning material Mo3Ge characterized by a large Ginzburg-Landau parameter. We observe that in the current driven ... [more ▼]

We study the instability of the superconducting state in a mesoscopic geometry for the low pinning material Mo3Ge characterized by a large Ginzburg-Landau parameter. We observe that in the current driven switching to the normal state from a nonlinear region of the Abrikosov flux flow, the mean critical vortex velocity reaches a limiting maximum velocity as a function of the applied magnetic fi eld. Based on time dependent Ginzburg-Landau simulations we argue that the observed behavior is owed to the high velocity vortex dynamics confi ned on a mesoscopic scale. We build up a general phase diagram which includes all possible dynamic confi gurations of Abrikosov lattice in a mesoscopic superconductor. [less ▲]

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See detailMonitoring surface water content using visible and short-wave infrared SPOT-5 data of wheat plots in irrigated semi-arid regions
Benabdelouahab, Tarik ULg; Balaghi, Riad; Hadria, Rachid et al

in International Journal of Remote Sensing (2015), 36(15), 4018-4036

Irrigated agriculture is an important strategic sector in arid and semi-arid regions. Given the large spatial coverage of irrigated areas, operational tools based on satellite remote sensing can ... [more ▼]

Irrigated agriculture is an important strategic sector in arid and semi-arid regions. Given the large spatial coverage of irrigated areas, operational tools based on satellite remote sensing can contribute to their optimal management. The aim of this study was to evaluate the potential of two spectral indices, calculated from SPOT-5 high-resolution visible (HRV) data, to retrieve the surface water content values (from bare soil to completely covered soil) over wheat fields and detect irrigation supplies in an irrigated area. These indices are the normalized difference water index (NDWI) and the moisture stress index (MSI), covering the main growth stages of wheat. These indices were compared to corresponding in situ measurements of soil moisture and vegetation water content in 30 wheat fields in an irrigated area of Morocco, during the 2012–2013 and 2013–2014 cropping seasons. NDWI and MSI were highly correlated with in situ measurements at both the beginning of the growing season (sowing) and at full vegetation cover (grain filling). From sowing to grain filling, the best correlation (R2 = 0.86; p < 0.01) was found for the relationship between NDWI values and observed soil moisture values. These results were validated using a k-fold cross-validation methodology; they indicated that NDWI can be used to estimate and map surface water content changes at the main crop growth stages (from sowing to grain filling). NDWI is an operative index for monitoring irrigation, such as detecting irrigation supplies and mitigating wheat water stress at field and regional levels in semi-arid areas. [less ▲]

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See detailDetermination of blood concentration levels of psychotrope medications in Rwandan patients
Hahirwa, Innocent; DENOOZ, Raphael ULg; Karangwa, Charles et al

in Acta Clinica Belgica (2015)

OBJECTIVES: In Rwanda, no therapeutic monitoring of psychotropic drugs is done. This results in difficult treatment optimisation and exposition to a high risk of toxicity and drug ineffectiveness for ... [more ▼]

OBJECTIVES: In Rwanda, no therapeutic monitoring of psychotropic drugs is done. This results in difficult treatment optimisation and exposition to a high risk of toxicity and drug ineffectiveness for patients under treatment. This study aimed to determine blood concentration levels of psychotropic drugs in Rwandan patients and identify problems associated with the lack of therapeutic drug monitoring (TDM) of these drugs. METHODS: The analysis was performed on 1 ml of serum sample using prazepam as internal standard. Regarding the step of sample preparation, we used a liquid-liquid extraction with a mixture of organic solvents: diethyl ether/dichloromethane/hexane/n-amyl alcohol (50/30/20/0.5:V/V). A Waters Alliance 2695 was used for analysis. The chromatography was run on a Symmetry C8 column and as mobile phase acetonitrile and phosphate buffer (pH 3.8) were used. RESULTS: Concerning the results, serum samples from 128 patients were analysed. Twenty-one different psychotropic drugs belonging to various pharmacological classes were detected and quantified. Analytical results were put into three categories based upon therapeutic reference ranges (TRR) of various drugs: subtherapeutic, therapeutic and supratherapeutic. For a total of 237 analyses, results within TRR represented 46% while 47 and 8% of results were, respectively, below and above TRR. CONCLUSION: It was therefore concluded that patients under psychotropic treatment in Rwanda are exposed to both the risk of drug ineffectiveness and the risk of toxicity (54%) with only 46% of results within the TRR. Consequently, TDM is needed to optimise psychotropic treatment in Rwandan patients. [less ▲]

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