References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailThermal properties of Ti-doped Cu–Zn soft ferrites used as thermally actuated material for magnetizing superconductors
Stachowiak, Piotr; Mucha, Jan; Szewczyk, Daria et al

in Journal of Physics : D Applied Physics (2016), 49

A great majority of widely used ferrite ceramics exhibit a relatively high temperature of order–disorder phase transition in their magnetic subsystem. For applications related to the magnetization process ... [more ▼]

A great majority of widely used ferrite ceramics exhibit a relatively high temperature of order–disorder phase transition in their magnetic subsystem. For applications related to the magnetization process of superconductors, however, a low value of Tc is required. Here we report and analyze in detail the thermal properties of bulk Ti-doped Cu–Zn ferrite ceramics Cu0.3Zn0.7Ti0.04Fe1.96O4 and Mg0.15Cu0.15Zn0.7Ti0.04Fe1.96O4. They are characterized by a Curie temperature in the range 120–170 K and a maximum DC magnetic susceptibility exceeding 20 for the Cu0.3Zn0.7Ti0.04Fe1.96O4 material. The temperature dependence of both the specific heat Cp and of the thermal conductivity κ, determined between 2 and 300 K, are found not to exhibit any peculiar feature at the magnetic transition temperature. The low-temperature dependence of both κ and the mean free path of phonons suggests a mesoscopic fractal structure of the grains. From the measured data, the characteristics of thermally actuated waves are estimated. The low magnetic phase transition temperature and suitable thermal parameters make the investigated ferrite ceramics applicable as magnetic wave producers in devices designed for magnetization of high-temperature superconductors. [less ▲]

Detailed reference viewed: 32 (15 ULg)
Full Text
Peer Reviewed
See detailPredictions of Pinning
Paruch, Patrycja; Ghosez, Philippe ULg

in Nature (2016), 534

A multiscale model has been implemented that provides accurate predictions of the behaviour of ferroelectric materials in electric fields, and might aid efforts to design devices such as sensors and ... [more ▼]

A multiscale model has been implemented that provides accurate predictions of the behaviour of ferroelectric materials in electric fields, and might aid efforts to design devices such as sensors and digital memory. [less ▲]

Detailed reference viewed: 17 (3 ULg)
Full Text
Peer Reviewed
See detailViruses within animal genome
De Brogniez, Alix ULg; Willems, Luc ULg

in Revue scientifique et technique - Office international des épizooties (2016)

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailNeural Activation During Mental Rotation in Complete Androgen Insensitivity Syndrome: the Influence of Sex Hormones and Sex Chromosomes.
van Hemmen, Judy; Veltman, Dick J.; Hoekzema, Elseline et al

in Cerebral Cortex (2016)

Sex hormones, androgens in particular, are hypothesized to play a key role in the sexual differentiation of the human brain. However, possible direct effects of the sex chromosomes, that is, XX or XY ... [more ▼]

Sex hormones, androgens in particular, are hypothesized to play a key role in the sexual differentiation of the human brain. However, possible direct effects of the sex chromosomes, that is, XX or XY, have not been well studied in humans. Individuals with complete androgen insensitivity syndrome (CAIS), who have a 46,XY karyotype but a female phenotype due to a complete androgen resistance, enable us to study the separate effects of gonadal hormones versus sex chromosomes on neural sex differences. Therefore, in the present study, we compared 46,XY men (n = 30) and 46,XX women (n = 29) to 46,XY individuals with CAIS (n = 21) on a mental rotation task using functional magnetic resonance imaging. Previously reported sex differences in neural activation during mental rotation were replicated in the control groups, with control men showing more activation in the inferior parietal lobe than control women. Individuals with CAIS showed a female-like neural activation pattern in the parietal lobe, indicating feminization of the brain in CAIS. Furthermore, this first neuroimaging study in individuals with CAIS provides evidence that sex differences in regional brain function during mental rotation are most likely not directly driven by genetic sex, but rather reflect gonadal hormone exposure. [less ▲]

Detailed reference viewed: 116 (15 ULg)
Full Text
Peer Reviewed
See detailShear Response of Prestressed Thin-Webbed Continuous Girders
Collins, Michael; Xie, Liping; Mihaylov, Boyan ULg et al

in ACI Structural Journal (2016)

While different design codes provide similar guidance for the flexural design of prestressed thin: webbed continuous girders, the shear design provisions differ greatly. This paper investigates these ... [more ▼]

While different design codes provide similar guidance for the flexural design of prestressed thin: webbed continuous girders, the shear design provisions differ greatly. This paper investigates these discrepancies with the help of eleven experiments and a number of analytical studies. Together these provide the basis for recommendations for engineers conducting the shear design for new girders or evaluating the shear capacity of existing girders. It is shown that the traditional ACI approach of taking Vc as the smaller of Vci, flexural:shear cracking load, and Vcw, web:shear cracking load, can significantly overestimate the shear strength of such girders particularly if they are highly prestressed and contain relatively small quantities of shear reinforcement. The other codes evaluated provided more conservative predictions. It is shown that the ACI predictions can be improved significantly by taking into account the effect of flexural stresses on web shear cracking. While the ACI code uses different shear strength equations for members subjected to external axial loads versus members subjected to internal prestressing forces, the studies summarized in this paper support the idea that unification of these ACI shear provisions is possible. [less ▲]

Detailed reference viewed: 74 (5 ULg)
Full Text
Peer Reviewed
See detailMonitoring the laccase reaction of vanillin and poplar hydrolysate
Sòti, Valentin; Jacquet, Nicolas ULg; Apers, Sandra et al

in Journal of Chemical Technology & Biotechnology (2016), 91(6), 1914-1922

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during ... [more ▼]

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during laccase enzyme reaction. This paper reports an investigation of the continuous UV absorbance follow-up of the laccase reaction with steam pretreated poplar hydrolysate. RESULTS: Vanillin was used as a model substrate and lignocellulose xylose rich fraction (XRF) as a biologically complex substrate for laccase detoxification. The reaction was followed by HPLC-UV as well as by UV spectrometric measurements. Results suggest that the reaction can be successfully monitored by measuring the change of UV absorbance at 280 nm, without previous compound separation. In case of XRF experiments the spectrophotometric follow-up is especially useful, as HPLC analysis takes a long time and provides less information than in case of single substrates. The method seems to be suitable for optimization and process control. CONCLUSION: The obtained results can help to construct a fast, easy and straightforward monitoring system for laccase-phenolic substrate reactions. [less ▲]

Detailed reference viewed: 49 (21 ULg)
Full Text
Peer Reviewed
See detailLa correction de l’expression écrite en langue étrangère et son exploitation pédagogique. Expliciter l’implicite ?
Noiroux, Kevin ULg; Simons, Germain ULg

in Les cahiers de l’Association des chercheurs et enseignants didacticiens des langues étrangères (acedle) (2016)

Detailed reference viewed: 69 (21 ULg)
Full Text
Peer Reviewed
See detailHigh serum sclerostin levels are associated with a better outcome in haemodialysis patients
Jean, Guillaume; Chazot, Charles; Bresson, Eric et al

in Nephron. Clinical Practice (2016)

Sclerostin is an osteocyte hormone that de- creases osteoblastogenesis. Sclerostin may play a key role in osteoporosis and also in vascular calcification (VC). In chron- ic kidney disease and ... [more ▼]

Sclerostin is an osteocyte hormone that de- creases osteoblastogenesis. Sclerostin may play a key role in osteoporosis and also in vascular calcification (VC). In chron- ic kidney disease and haemodialysis (HD) patients, serum sclerostin levels are high. Aim: To assess the correlation of serum sclerostin levels with VC, bone mineral density (BMD), and survival rate in HD patients. Methods: A cross-sectional study was conducted in prevalent HD patients to correlate serum sclerostin tertiles with the Kauppila aortic calcification score, BMD scores and survival rate. Results: We studied 207 patients who had a mean serum sclerostin level of 1.9 ± 0.7 ng/ml. Compared to patients in the 1st tertile of serum sclerostin levels (0.6–1.53 ng/ml), patients in the 3rd tertile (2.2–4.6 ng/ml) were significantly older (73.7 ± 12 vs. 64.7 ± 18 years), more frequently of the male gender (74 vs. 48%), had lower serum bone-specific alkaline phosphatases values (14 ± 9 vs. 20.4 ± 13 µg/l), were less frequently treated with alfacalcidol, displayed lower aortic calcification scores (9.5 ± 5 vs. 12.5 ± 7/24) and had higher BMD scores. Furthermore, patients of the 3rd tertile displayed a lower mortality rate compared to tertile 1 using multivariable adjusted Cox mod- el (hazard ratio 0.5, 95% CI 0.25–0.93, p = 0.03). The main fac- tors associated with VC score were age, diabetes, cardiovas- cular disease, CRP level and Warfarin use. Conclusion: Our study of HD patients shows that higher serum sclerostin lev- els are associated with higher BMD, lower aortic calcification scores, and a better survival rate. [less ▲]

Detailed reference viewed: 8 (3 ULg)
Full Text
Peer Reviewed
See detailEfficiency of delivery observed treatment in hemodialysis patients: the example of the native vitamin D therapy
DELANAYE, Pierre ULg; CAVALIER, Etienne ULg; Fafin, Coraline et al

in Journal of Nephrology (2016), 29(1), 99-103

Introduction Adherence to therapy is a relevant challenge in chronic hemodialysis patients. The directly observed therapy (DOT) could be an effective method to increase adherence for specific therapies ... [more ▼]

Introduction Adherence to therapy is a relevant challenge in chronic hemodialysis patients. The directly observed therapy (DOT) could be an effective method to increase adherence for specific therapies. We aimed to study the performance of DOT versus home medication. We follow the impact of providing native vitamin D directly by the nurse after a dialysis session on the 25-hydroxyvitamin [25(OH)D] concentrations. Methods In this observational study, we included 38 dialysis patients treated by stable dosage of cholecalciferol. DOT was implemented in December 2010. We considered the concentrations of 25-OH vitamin D three times before (T1 = June 2010, T2 = July 2010 and T3 = September 2010) and three times after the modification of prescription (T4 = February 2011, T5 = March 2011 and T6 = April 2011). Results Median age was 72 [62; 79] years and 48 % were diabetics. Mean body mass index was 26 ± 5 kg/m2 and median dialysis vintage was 20 [8; 46] months. The patients were compared to themselves. Before DOT, median concentrations of 25(OH)D were 27 (14–36), 23 (17–31), 31 (22–38) ng/mL at T1, T2 and T3, respectively. When DOT was effective, the concentrations significantly increased to 34 (28–44), 35 (29–41), 39 (32–47) ng/mL at T4, T5 and T6, respectively. Before DOT, 19 patients (50 %) reached the target of 30 ng/mL. After DOT, 29 patients (76 %) reached the target concentration of 30 ng/ mL. Conclusions In hemodialysis patients, DOT is both simple and effective to increase the therapeutic impact to native vitamin D. [less ▲]

Detailed reference viewed: 29 (11 ULg)
Full Text
Peer Reviewed
See detailA roadmap to multifactor dimensionality reduction methods.
Gola, Damian; Mahachie John, Jestinah M.; Van Steen, Kristel ULg et al

in Briefings in Bioinformatics (2016), 17(2), 293-308

Complex diseases are defined to be determined by multiple genetic and environmental factors alone as well as in interactions. To analyze interactions in genetic data, many statistical methods have been ... [more ▼]

Complex diseases are defined to be determined by multiple genetic and environmental factors alone as well as in interactions. To analyze interactions in genetic data, many statistical methods have been suggested, with most of them relying on statistical regression models. Given the known limitations of classical methods, approaches from the machine-learning community have also become attractive. From this latter family, a fast-growing collection of methods emerged that are based on the Multifactor Dimensionality Reduction (MDR) approach. Since its first introduction, MDR has enjoyed great popularity in applications and has been extended and modified multiple times. Based on a literature search, we here provide a systematic and comprehensive overview of these suggested methods. The methods are described in detail, and the availability of implementations is listed. Most recent approaches offer to deal with large-scale data sets and rare variants, which is why we expect these methods to even gain in popularity. [less ▲]

Detailed reference viewed: 7 (2 ULg)
Full Text
Peer Reviewed
See detailRadio-frequency magnetron sputtering: a versatile tool for CdSe quantum dots depositions with controlled properties
Dahi, Abdellatif; Colson, Pierre ULg; Jamin, Claire et al

in Journal of Material and Environmental Sciences (2016), 7(7), 2277-2287

CdSe nanoparticles are of great interest for many applications. However, their size, shape, and aggregation are still difficult to control by the conventional synthesis methods. Here, we report on the ... [more ▼]

CdSe nanoparticles are of great interest for many applications. However, their size, shape, and aggregation are still difficult to control by the conventional synthesis methods. Here, we report on the synthesis of CdSe quantum dots (QDs), with an average diameter less than 10 nm, using radio-frequency magnetron sputtering (RFMS) on glass and silicon substrates at 25 °C. First, results show that a target-substrate distance of 13.5 cm and a chamber pressure of 2.2 .10-1 mbar were required to deposit a CdSe QDs layer on the substrates. The morphology and optical properties of CdSe QDs were then studied as a function of RF power and deposition time. The size of CdSe QDs increases with increasing both the RF power and the deposition time. UV-visible spectroscopy shows that the CdSe QDs layer deposited on the glass-substrate by RFMS has almost the same optical properties as the one obtained from commercial CdSe QDs solutions. In both cases, a shift of the characteristic absorption band of CdSe QDs towards the higher wavenumbers is observed with the QDs size increase. AFM confirms the success of CdSe QDs layer deposition by RFMS: CdSe QDs with a mean diameter of 7.5 ± 2 nm were observed for a RF power of 14 W, a chamber pressure of 2.2 .10-1 mbar, a target-substrate distance of 13.5 cm and a deposition time of 7.5 min (optimal values). With these parameters, the coverage of the substrate by the nano-objects is estimated at 25-30 % of the overall surface. [less ▲]

Detailed reference viewed: 40 (8 ULg)
Full Text
Peer Reviewed
See detailRecent Advances on the Oil-Free Scroll Compressor
Bin, Peng; Legros, Arnaud; Lemort, Vincent ULg et al

in Recent Patents on Mechanical Engineering (2016), 9

Traditionally, scroll compressors are mainly made of metallic parts and oil is used to lubricate the friction surfaces and reduce discharge temperature and leakage. But for the food processing, medical ... [more ▼]

Traditionally, scroll compressors are mainly made of metallic parts and oil is used to lubricate the friction surfaces and reduce discharge temperature and leakage. But for the food processing, medical systems, textile manufacturing, fuel cell system, and other super-clean fields, the oil-less operation is critical. The oil is strictly forbidden in the working chambers of the scroll compressor in order to get the oil-free compressed air. So it is very important to develop the oil-free scroll compressor (OFSC). In this paper, the working principle and structure characteristics of the OFSC are investigated. Some of research works and the recent patents in this area are described and analyzed in detail, especially the water injection and air cooling OFSC. The future development on an OFSC is also presented. The analysis results demonstrated that there is dramatic growth potential in OFSC field. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailAssessment of methods of detection of water estrogenicity for their use as monitoring tools in a process of estrogenicity removal
Blavier; Songulashvili; Simon, Coraline ULg et al

in Environmental Technology (2016)

Detailed reference viewed: 15 (4 ULg)
Full Text
Peer Reviewed
See detailSuitability of soils and river deposits from Marrakech for the manufacturing of earthenware
El Boudour El Idrissi, Hicham ULg; Daoudi, Lahcen; El Ouahabi, Meriam ULg et al

in Applied Clay Science (2016), 129

This paper investigates the suitability of clayey materials originating from semi-arid soil and river sediments, used by potters in the Agafay region for the manufacture of ceramic products. The clay ... [more ▼]

This paper investigates the suitability of clayey materials originating from semi-arid soil and river sediments, used by potters in the Agafay region for the manufacture of ceramic products. The clay samples were subjected to particle-size analysis, X-ray diffraction and X-ray fluorescence to investigate their physical, mineralogical and chemical characteristics respectively. The physical behaviour of the intermediate products was studied at the shaping and drying stages of the ceramics manufacturing process through the Atterberg limits and the plot of the Bigot curve respectively. The final product characteristics were determined through porosity tests, flexural and compressive strengths tests. Based on results obtained, the raw materials turn out to be suitable characteristics for the manufacture of earthenware products. The application of the suggested recommendations is worthy for the improvement of the products based on such raw materials. [less ▲]

Detailed reference viewed: 53 (15 ULg)
Full Text
Peer Reviewed
See detailEfficient standard error formulas of ability estimators with dichotomous item response models
Magis, David ULg

in Psychometrika (2016), 81

This paper focuses on the computation of asymptotic standard errors (ASE) of ability estimators with dichotomous item response models. A general framework is considered and ability estimators are defined ... [more ▼]

This paper focuses on the computation of asymptotic standard errors (ASE) of ability estimators with dichotomous item response models. A general framework is considered and ability estimators are defined from a very restricted set of assumptions and formulas. This approach encompasses most standard methods such as maximum likelihood, weighted likelihood, maximum a posteriori and robust estimators. A general formula for the ASE is derived from the theory of M-estimation. Well-known results are found back as particular cases for the maximum and robust estimators, while new ASE proposals for the weighted likelihood and maximum a posteriori estimators are presented. These new formulas are compared to traditional ones by means of a simulation study under Rasch modeling. [less ▲]

Detailed reference viewed: 21 (6 ULg)
Full Text
Peer Reviewed
See detailComment je traite ....... Le delirium chez le patient âgé
CHRISTELBACH, Sophie ULg; ALLEPAERTS, Sophie ULg; PETERMANS, Jean ULg

in Revue Médicale de Liège (2016)

Detailed reference viewed: 25 (8 ULg)
Full Text
Peer Reviewed
See detailWhat mediates postoperative risk in obstructive sleep apnea: airway obstruction, nocturnal hypoxia or both ?
DEFLANDRE, Eric; BONHOMME, Vincent ULg; BRICHANT, Jean-François ULg et al

in Canadian Journal of Anaesthesia = Journal Canadien d'Anesthésie (2016)

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailAssessing the ability of rural agrarian areas to provide culturalecosystem services (CES): A multi scale social indicator framework(MSIF)
Carvalho-Ribeiro, Sónia; Pinto Correia, Teresa; Paracchini, Maria Luisa et al

in Land Use Policy (2016), 53

Assessing the ways in which rural agrarian areas provide Cultural Ecosystem Services (CES) is provingdifficult to achieve. This research has developed an innovative methodological approach named as ... [more ▼]

Assessing the ways in which rural agrarian areas provide Cultural Ecosystem Services (CES) is provingdifficult to achieve. This research has developed an innovative methodological approach named as MultiScale Indicator Framework (MSIF) for capturing the CES embedded into the rural agrarian areas. Thisframework reconciles a literature review with a transdisciplinary participatory workshop. Both of thesesources reveal that societal preferences diverge upon judgemental criteria which in turn relate to differentvisual concepts that can be drawn from analyzing attributes, elements, features and characteristics of ruralareas. We contend that it is now possible to list a group of possible multi scale indicators for stewardship,diversity and aesthetics. These results might also be of use for improving any existing European indicatorsframeworks by also including CES. This research carries major implications for policy at different levels ofgovernance, as it makes possible to target and monitor policy instruments to the physical rural settingsso that cultural dimensions are adequately considered. There is still work to be developed on regionalspecific values and thresholds for each criteria and its indicator set. In practical terms, by developing theconceptual design within a common framework as described in this paper, a considerable step forwardtoward the inclusion of the cultural dimension in European wide assessments can be made. [less ▲]

Detailed reference viewed: 16 (4 ULg)
Full Text
Peer Reviewed
See detailOn-demand continuous flow production of pharmaceuticals in a compact, reconfigurable system
Adamo, Andrea; Beingessner, Rachel L.; Behnam, Mohsen et al

in Science (2016), 352

Pharmaceutical manufacturing typically uses batch processing at multiple locations. Disadvantages of this approach include long production times and the potential for supply chain disruptions. As a ... [more ▼]

Pharmaceutical manufacturing typically uses batch processing at multiple locations. Disadvantages of this approach include long production times and the potential for supply chain disruptions. As a preliminary demonstration of an alternative approach, we report here the continuous-flow synthesis and formulation of active pharmaceutical ingredients in a compact, reconfigurable manufacturing platform. Continuous end-to-end synthesis in the refrigerator-sized [1.0 meter (width) × 0.7 meter (length) × 1.8 meter (height)] system produces sufficient quantities per day to supply hundreds to thousands of oral or topical liquid doses of diphenhydramine hydrochloride, lidocaine hydrochloride, diazepam, and fluoxetine hydrochloride that meet U.S. Pharmacopeia standards. Underlying this flexible plug-and-play approach are substantial enabling advances in continuous-flow synthesis, complex multistep sequence telescoping, reaction engineering equipment, and real-time formulation. [less ▲]

Detailed reference viewed: 73 (13 ULg)
Full Text
Peer Reviewed
See detailDiscretization of the divergence formulation of the bed slope term in the shallow-water equations and consequences in terms of energy balance
Bruwier, Martin ULg; Archambeau, Pierre ULg; Erpicum, Sébastien ULg et al

in Applied Mathematical Modelling (2016)

In this research, the influence on energy balance of the discretization scheme of the divergence formulation of the bed slope term in the shallow-water equations is analysed theoretically (for a single ... [more ▼]

In this research, the influence on energy balance of the discretization scheme of the divergence formulation of the bed slope term in the shallow-water equations is analysed theoretically (for a single topographic step) and based on two numerical tests. Different values of the main parameter controlling the discretization scheme of the divergence formulation are analysed to identify the formulation which minimizes the energy variation resulting from the discretization. For a wide range of ambient Froude numbers and relative step heights, the theoretical value of the control parameter minimizing the energy variation falls within a very narrow range, which can reasonably be approximated by a single “optimal” value. This is a result of high practical relevance for the design of accurate numerical schemes, as confirmed by the results of the numerical tests. [less ▲]

Detailed reference viewed: 35 (12 ULg)
Full Text
Peer Reviewed
See detailSevere Prolonged Cough as Presenting Manifestation of FIP1L1-PDGFRA+ Chronic Eosinophilic Leukaemia: A Widely Ignored Association.
Roufosse, Florence; Heimann, Pierre; LAMBERT, Frédéric ULg et al

in Respiration; international review of thoracic diseases (2016)

Chronic eosinophilic leukaemia associated with the FIP1L1-PDGFRA fusion gene (F/P+ CEL) is a rare cause of marked persistent hypereosinophilia, arising almost exclusively in male patients. Clinical ... [more ▼]

Chronic eosinophilic leukaemia associated with the FIP1L1-PDGFRA fusion gene (F/P+ CEL) is a rare cause of marked persistent hypereosinophilia, arising almost exclusively in male patients. Clinical presentations are heterogeneous with a higher incidence of eosinophil-mediated cardiomyopathy than in other hypereosinophilic syndrome variants. Features of chronic myeloproliferative disease are often present, including splenomegaly and elevated serum vitamin B12 levels. The diagnosis is made by fluorescence in situ hybridization (FISH) showing the deletion of the CHIC2 locus and/or RT-PCR showing the FIP1L1-PDGFRA fusion transcript. Treatment with imatinib mesylate, a tyrosine kinase inhibitor, results in rapid and complete resolution of hypereosinophilia and associated symptoms, except for those related to sub-endocardial fibrosis that may be irreversible. We report the case of a male patient in whom isolated intractable cough remained the only clinical manifestation of F/P+ CEL for 4 years. Furthermore, eosinophil autofluorescence, an as yet unreported artefact in this setting, precluded the detection of the CHIC2 deletion and further delayed diagnosis, underlining that both FISH and RT-PCR should be performed when this disease is suspected. [less ▲]

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailElastin density: Link between histological and biomechanical properties of vaginal tissue in women with pelvic organ prolapse?
DE LANDSHEERE, Laurent ULg; Brieu, Mathias; Blacher, Silvia ULg et al

in International Urogynecology Journal & Pelvic Floor Dysfunction (2016)

INTRODUCTION AND HYPOTHESIS: The aim of the study was to correlate histological and biomechanical characteristics of the vaginal wall in women with pelvic organ prolapse (POP). METHODS: Tissue samples ... [more ▼]

INTRODUCTION AND HYPOTHESIS: The aim of the study was to correlate histological and biomechanical characteristics of the vaginal wall in women with pelvic organ prolapse (POP). METHODS: Tissue samples were collected from the anterior [point Ba; POP Questionnaire (POP-Q)] and/or posterior (point Bp; POP-Q) vaginal wall of 15 women who underwent vaginal surgery for POP. Both histological and biomechanical assessments were performed from the same tissue samples in 14 of 15 patients. For histological assessment, the density of collagen and elastin fibers was determined by combining high-resolution virtual imaging and computer-assisted digital image analysis. For biomechanical testing, uniaxial tension tests were performed to evaluate vaginal tissue stiffness at low (C0) and high (C1) deformation rates. RESULTS: Biomechanical testing highlights the hyperelastic behavior of the vaginal wall. At low strains (C0), vaginal tissue appeared stiffer when elastin density was low. We found a statistically significant inverse relationship between C0 and the elastin/collagen ratio (p = 0.048) in the lamina propria. However, at large strain levels (C1), no clear relationship was observed between elastin density or elastin/collagen ratio and stiffness, likely reflecting the large dispersion of the mechanical behavior of the tissue samples. CONCLUSION: Histological and biomechanical properties of the vaginal wall vary from patient to patient. This study suggests that elastin density deserves consideration as a relevant factor of vaginal stiffness in women with POP. [less ▲]

Detailed reference viewed: 18 (2 ULg)
Full Text
Peer Reviewed
See detailMitochondrial function is altered in horse atypical myopathy
Lemieux, Hélène; BOEMER, François ULg; van Galen, Gaby et al

in Mitochondrion (2016), 30

Equine atypical myopathy in Europe is a fatal rhabdomyolysis syndrome that results from the ingestion of hypoglycin A contained in seeds and seedlings of Acer pseudoplatanus. The hallmark of atypical ... [more ▼]

Equine atypical myopathy in Europe is a fatal rhabdomyolysis syndrome that results from the ingestion of hypoglycin A contained in seeds and seedlings of Acer pseudoplatanus. The hallmark of atypical myopathy consists of a severe alteration in the energy metabolism including a severe impairment in muscle mitochondrial respiration that could contribute to its high death rate [less ▲]

Detailed reference viewed: 16 (6 ULg)
Full Text
Peer Reviewed
See detailApparent changes of the Ordovician-Mississippian plant diversity
Cascales-Miñana, Borja ULg

in Review of Palaeobotany and Palynology (2016)

Detailed reference viewed: 19 (5 ULg)
Full Text
Peer Reviewed
See detailCan computer vision problems benefit from structured hierarchical classification?
Hoyoux, Thomas ULg; Rodríguez-Sánchez, Antonio J.; Piater, Justus H.

in Machine Vision & Applications (2016)

Detailed reference viewed: 29 (6 ULg)
Full Text
Peer Reviewed
See detailSpecifying Concrete Repair Materials
Vaysburd, Alex; Bissonnette, Benoît; Garbacz, Andrzej et al

in Materialy Budowlane (2016), 3(523), 42-45

Specification of materials for concrete repair is a complex task requiring broad knowledge of materials science, engineering and construction practice. In this paper, several issues important for proper ... [more ▼]

Specification of materials for concrete repair is a complex task requiring broad knowledge of materials science, engineering and construction practice. In this paper, several issues important for proper design and implementation of concrete repair are discussed. It is stressed that the specification documentation is not a formality, but rather a critically important engineering step in view of fulfilling the durability and service life requirements. [less ▲]

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailMigration policy reforms in the context of economic and political crises: the case of Belgium
Gsir, Sonia ULg; Lafleur, Jean-Michel ULg; Stanek, Mikolaj

in Journal of Ethnic & Migration Studies (2016)

A body of literature has examined the role of ‘crises’ on policymaking. Yet, we observe that endogenous or exogenous events called ‘crisis-events’ are often randomly chosen as sweeping explanations for ... [more ▼]

A body of literature has examined the role of ‘crises’ on policymaking. Yet, we observe that endogenous or exogenous events called ‘crisis-events’ are often randomly chosen as sweeping explanations for reforms in migration and integration policy. Thus, we attempt to find answers for the question of how the latest financial and economic crisis affected policy-making in the area of migration and integration. We apply a combination of interestbased and ideas-based theories to the case of Belgium in order to question the role of crises in policy reforms in the field of migration and integration. Multiple political and economic crises have affected the country since 2007. Examining these crises and immigration politics we argue that electoral competition both between and within the Francophone and Flemish party systems continues to be the main driver of migration and integration policy reform. Yet, we also discover a cumulative effect of economic and political crises: while the intention of restricting immigration has remained largely unchanged over the years, the policy instruments employed to reach this objective have changed with the political and economic crises. [less ▲]

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailMesure des flux de CO2 et séquestration de carbone dans les écosystèmes terrestres ouest-africains (Synthèse Bibliographique)
Ago, Expédit Evariste ULg; Agbossou, Euloge Kossi; Ozer, Pierre ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2016), 20(1), 1-15

In West Africa, as elsewhere in other parts of the world, preserving terrestrial ecosystems has proven essential to any emissions mitigation policy for greenhouse gases, notably carbon dioxide. A ... [more ▼]

In West Africa, as elsewhere in other parts of the world, preserving terrestrial ecosystems has proven essential to any emissions mitigation policy for greenhouse gases, notably carbon dioxide. A meaningful assessment of the contribution of a given region to the global carbon cycle implies the need to think in terms of balance, taking into account the totality of the carbon export and import within the ecosystems [less ▲]

Detailed reference viewed: 47 (13 ULg)
Full Text
Peer Reviewed
See detailWhat controls the local time extent of flux transfer events?
Milan, S. E.; Imber, S. M.; Carter, J. A. et al

in Journal of Geophysical Research. Space Physics (2016), 121

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailThe transactional process between the relationships with caregivers and children's externalizing behavior
Roskam, Isabelle; Stievenart, Marie ULg; de Mol, Jan

in Journal of Applied Developmental Psychology (2016), 42

Externalizing behavior (EB) has been found to be pervasive in children across different interactional systems. The transactional model is one of the most interesting and plausible mechanisms explaining ... [more ▼]

Externalizing behavior (EB) has been found to be pervasive in children across different interactional systems. The transactional model is one of the most interesting and plausible mechanisms explaining the development of behavioral problems (Sameroff, 2009). The main goal of the study is to test bidirectional and recursive transactional relations between the quality of the caregiver–child relationship and children's externalizing behavior. The transactional model was tested in three-wave longitudinal cross-lagged models involving 117 children (78.5% boys) aged 4 at the beginning of the study and three caregivers, i.e. their mother, father and teacher. All of the children had been clinically referred for externalizing behavior. Themulti-informant three-wave design was an original feature of this research. The results provided no evidence for a transactional process. The results suggest the singularity of each ofthese three interactional systems. They are discussed from the theoretical viewpoint and in terms of their clinical implications. [less ▲]

Detailed reference viewed: 51 (2 ULg)
Full Text
Peer Reviewed
See detailLearning of interval and general type-2 fuzzy logic systems using simulated annealing: Theory and practice
Almaraashi, Majid; John, Robert; Hopgood, Adrian ULg et al

in Information Sciences (2016), 360

This paper reports the use of simulated annealing to design more efficient fuzzy logic systems to model problems with associated uncertainties. Simulated annealing is used within this work as a method for ... [more ▼]

This paper reports the use of simulated annealing to design more efficient fuzzy logic systems to model problems with associated uncertainties. Simulated annealing is used within this work as a method for learning the best configurations of interval and general type-2 fuzzy logic systems to maximize their modeling ability. The combination of simulated annealing with these models is presented in the modeling of four benchmark problems including real-world problems. The type-2 fuzzy logic system models are compared in their ability to model uncertainties associated with these problems. Issues related to this combination between simulated annealing and fuzzy logic systems, including type-2 fuzzy logic systems, are discussed. The results demonstrate that learning the third dimension in type-2 fuzzy sets with a deterministic defuzzifier can add more capability to modeling than interval type-2 fuzzy logic systems. This finding can be seen as an important advance in type-2 fuzzy logic systems research and should increase the level of interest in the modeling applications of general type-2 fuzzy logic systems, despite their greater computational load. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailProbing the low-frequency vortex dynamics in a nanostructured superconducting strip
de Souza Silva, Clecio C.; Raes, Bart; Brisbois, Jérémy ULg et al

in Physical Review B (2016)

We investigate by scanning susceptibility microscopy the response of a thin Pb strip, with a square array of submicron antidots, to a low-frequency ac magnetic field applied perpendicularly to the film ... [more ▼]

We investigate by scanning susceptibility microscopy the response of a thin Pb strip, with a square array of submicron antidots, to a low-frequency ac magnetic field applied perpendicularly to the film plane. By mapping the local permeability of the sample within the field range where vortices trapped by the antidots and interstitial vortices coexist, we observed two distinct dynamical regimes occurring at different temperatures. At a temperature just below the superconducting transition, T/Tc = 0.96, the sample response is essentially dominated by the motion of highly mobile interstitial vortices. However, at a slightly lower temperature, T/Tc = 0.93, the interstitial vortices freeze up leading to a strong reduction of the ac screening length. We propose a simple model for the vortex response in this system which fits well to the experimental data. Our analysis suggests that the observed switching to the high mobility regime stems from a resonant effect, where the period of the ac excitation is just large enough to allow interstitial vortices to thermally hop through the weak pinning landscape produced by random material defects. This argument is further supported by the observation of a pronounced enhancement of the out-of-phase response at the crossover between both dynamical regimes. [less ▲]

Detailed reference viewed: 24 (3 ULg)
Full Text
Peer Reviewed
See detailBrabantophyton, a new genus with stenokolealean affinities from a Middle to earliest Upper Devonian locality from Belgium
Momont, Nicolas ULg; Gerrienne, Philippe ULg; Prestianni, Cyrille

in Review of Palaeobotany and Palynology (2016)

A new taxon with stenokolealean affinities, Brabantophyton runcariense gen. et sp. nov., is described from seven pyrite permineralized axes collected from the mid Givetian to earliest Frasnian (late ... [more ▼]

A new taxon with stenokolealean affinities, Brabantophyton runcariense gen. et sp. nov., is described from seven pyrite permineralized axes collected from the mid Givetian to earliest Frasnian (late Middle to earliest Upper Devonian) locality of Ronquières (Belgium). The specimens include stems and lateral organs. The stems are characterized by a protostele dissected into three primary ribs, each of them dividing into two secondary ribs. The protostele shows a central protoxylem strand and numerous strands distributed along the midplanes of the ribs. The vascular supply to lateral organ is composed of two pairs of traces, produced at the same time by the two ribs issued from a single primary rib of the protostele. Within each pair, the shape and the size of the traces are unequal: one is T-shaped and the other is oval to reniform. The T-shaped traces of each pair face each other. The inner cortex of the lateral organs is parenchymatous and the outer cortex is sparganum-like. The specimens of Brabantophyton runcariense show many similarities with the stenokolealean genus Crossia virginiana Beck and Stein, but the vascular supply of lateral organs of the latter consists of a more symmetrical and distinctively simpler pair of traces. Brabantophyton represents the first report of the Stenokoleales in southeastern Laurussia. The characteristics of the Brabantophyton protostele compare better with the anatomy of the radiatopses, and, within the latter, particularly with basal seed plants. [less ▲]

Detailed reference viewed: 46 (5 ULg)
Full Text
Peer Reviewed
See detailHomologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
Ansseau, Eugénie; Eidahl, JO; Lancelot, Céline et al

in PLoS ONE (2016)

Detailed reference viewed: 8 (2 ULg)
Full Text
Peer Reviewed
See detailShort term impact of selective logging on a western lowland gorilla population
Haurez, Barbara ULg; Tagg, Nikki; Petre, Charles-Albert ULg et al

in Forest Ecology & Management (2016), 364

Selective timber production is implemented over a large proportion of the world’s tropical forests. Within these forest ecosystems, the frugivore community contributes important ecological services ... [more ▼]

Selective timber production is implemented over a large proportion of the world’s tropical forests. Within these forest ecosystems, the frugivore community contributes important ecological services through animal-mediated seed dispersal. However, there is no clear understanding of the impacts of logging on wildlife or of the extent to which seed dispersal is preserved in logged forests. Given its tendency for nesting in light gaps, the western lowland gorilla is likely to provide directed-dispersal services to a wide range of tree species. Production forests preserved from poaching have been reported to harbor high densities of gorillas, but the monitoring of gorilla populations subjected to logging is poorly documented. This study investigated gorilla density and nesting behavior after timber exploitation in a logging concession in southeast Gabon. Nest count censuses were performed on line transects, before and after the second felling cycle. Gorilla density dropped from 1.5 (116.7 nests km 2, 95% CI = 83.4–163.5) to 1.0 (64.9 nests km 2, % CI = 32.6–129.5) weaned gorilla km 2 4–6 months after logging, then rose to 2.6 (176.3 nests km 2, 95% CI = 113.5–274.1) gorillas km 2 9–11 months after logging. A consistent preference for nesting in open canopy terra firma forest was observed during all censuses. This study demonstrates the short-term resilience of the western lowland gorilla to selective timber harvesting, and argues that they offer a continued contribution to directed-dispersal services within months after logging. Although a long-term monitoring of gorillas in a logged forest should be undertaken, the role of this species in logged forest recovery is thought to be important. The preservation of gorilla should receive particular consideration by forest managers. [less ▲]

Detailed reference viewed: 45 (6 ULg)
Full Text
Peer Reviewed
See detailDes terrasses de fond de vallée de la Meuse dans la région de Huy (Belgique)
Juvigné, Etienne ULg; Demoulin, Alain ULg; Houbrechts, Geoffrey ULg et al

in BSGLg (2016), 65

Des alluvions mosanes mises au jour dans quatre chantiers de la ville d’Andenne et d’autres fossilisées dans le méandre abandonné de Leumont (Huy) sont mises en relation avec d’autres terrasses mosanes ... [more ▼]

Des alluvions mosanes mises au jour dans quatre chantiers de la ville d’Andenne et d’autres fossilisées dans le méandre abandonné de Leumont (Huy) sont mises en relation avec d’autres terrasses mosanes signalées antérieurement dans des travaux géotechniques réalisés entre Andenne et Hermalle-sous-Huy. Enfoui sous des dépôts atteignant localement 30 m d’épaisseur, le dernier cailloutis du méandre recoupé de Leumont se raccorde parfaitement à la plaine alluviale actuelle à sa sortie, et est en fait une section abandonnée de cette dernière. À l’entrée du méandre, il se situe toutefois 1,5 à 2 m au-dessus du cailloutis de la plaine alluviale actuelle, ce pour quoi nous l’appelons Terrasse (T.) locale de Wanze 2. Dans ce même méandre, il existe un autre cailloutis mosan qui se situe, de base à base, 6 m plus haut que le niveau précité et est lui-même fossilisé sous une vingtaine de mètres dépôts ; nous l’avons nommé T. de Wanze 1. Les âges respectifs du recoupement du méandre et de la T. de Wanze 1 ont été estimés de façon indirecte, suggérant qu’à Huy, (1) la plaine alluviale est à son niveau actuel depuis le début de la dernière glaciation, et (2) la Meuse a été active sur la T. de Wanze 1 pendant l’avant-dernière glaciation (Stade Isotopique Marin 6). Des taux d’incision de la Meuse et de la surrection régionale qui l’a occasionnée sont estimés à partir de la T. de Wanze 1 et d’une terrasse plus élevée présente à Naxhelet, juste à l’ouest du méandre de Leumont. Ils suggèrent une vitesse constante de ~0,06 mm/a pour la surrection de la région de Huy depuis ~600 ka. [less ▲]

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailFDG PET/CT texture analysis for predicting the outcome of lung cancer treated by stereotactic body radiation therapy.
LOVINFOSSE, Pierre ULg; Janvary, Zsolt Levente; COUCKE, Philippe ULg et al

in European journal of nuclear medicine and molecular imaging (2016)

INTRODUCTION: With 18F-FDG PET/CT, tumor uptake intensity and heterogeneity have been associated with outcome in several cancers. This study aimed at investigating whether 18F-FDG uptake intensity, volume ... [more ▼]

INTRODUCTION: With 18F-FDG PET/CT, tumor uptake intensity and heterogeneity have been associated with outcome in several cancers. This study aimed at investigating whether 18F-FDG uptake intensity, volume or heterogeneity could predict the outcome in patients with non-small cell lung cancers (NSCLC) treated by stereotactic body radiation therapy (SBRT). METHODS: Sixty-three patients with NSCLC treated by SBRT underwent a 18F-FDG PET/CT before treatment. Maximum and mean standard uptake value (SUVmax and SUVmean), metabolic tumoral volume (MTV), total lesion glycolysis (TLG), as well as 13 global, local and regional textural features were analysed. The predictive value of these parameters, along with clinical features, was assessed using univariate and multivariate analysis for overall survival (OS), disease-specific survival (DSS) and disease-free survival (DFS). Cutoff values were obtained using logistic regression analysis, and survivals were compared using Kaplan-Meier analysis. RESULTS: The median follow-up period was 27.1 months for the entire cohort and 32.1 months for the surviving patients. At the end of the study, 25 patients had local and/or distant recurrence including 12 who died because of the cancer progression. None of the clinical variables was predictive of the outcome, except age, which was associated with DFS (HR 1.1, P = 0.002). None of the 18F-FDG PET/CT or clinical parameters, except gender, were associated with OS. The univariate analysis showed that only dissimilarity (D) was associated with DSS (HR = 0.822, P = 0.037), and that several metabolic measurements were associated with DFS. In multivariate analysis, only dissimilarity was significantly associated with DSS (HR = 0.822, P = 0.037) and with DFS (HR = 0.834, P < 0.01). CONCLUSION: The textural feature dissimilarity measured on the baseline 18F-FDG PET/CT appears to be a strong independent predictor of the outcome in patients with NSCLC treated by SBRT. This may help selecting patients who may benefit from closer monitoring and therapeutic optimization. [less ▲]

Detailed reference viewed: 53 (6 ULg)
Full Text
Peer Reviewed
See detailDe la perversion au pervers ; du sexuel à l’adaptatif
Englebert, Jérôme ULg

in Psychosomatique Relationnelle (2016), 6

Detailed reference viewed: 101 (25 ULg)
Full Text
Peer Reviewed
See detailL'impôt sur les revenus des salariés et l'extranéité (2e partie)
Docclo, Caroline ULg

in Journal des Tribunaux du Travail (2016)

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailThe internal consistency of the North Sea carbonate system
Salt, Lesley A.; Thomas, Helmuth; Bozec, Yann et al

in Journal of Marine Systems (2016), 157

Abstract In 2002 (February) and 2005 (August), the full suite of carbonate system parameters (total alkalinity (AT), dissolved inorganic carbon (DIC), pH, and partial pressure of \{CO2\} (pCO2) were ... [more ▼]

Abstract In 2002 (February) and 2005 (August), the full suite of carbonate system parameters (total alkalinity (AT), dissolved inorganic carbon (DIC), pH, and partial pressure of \{CO2\} (pCO2) were measured on two re-occupations of the entire North Sea basin, with three parameters (AT, DIC, pCO2) measured on four additional re-occupations, covering all four seasons, allowing an assessment of the internal consistency of the carbonate system. For most of the year, there is a similar level of internal consistency, with \{AT\} being calculated to within ± 6 μmol kg− 1 using \{DIC\} and pH, \{DIC\} to ± 6 μmol kg− 1 using \{AT\} and pH, pH to ± 0.008 using \{AT\} and pCO2, and pCO2 to ± 8 μatm using \{DIC\} and pH, with the dissociation constants of Millero et al. (2006). In spring, however, we observe a significant decline in the ability to accurately calculate the carbonate system. Lower consistency is observed with an increasing fraction of Baltic Sea water, caused by the high contribution of organic alkalinity in this water mass, not accounted for in the carbonate system calculations. Attempts to improve the internal consistency by accounting for the unconventional salinity–borate relationships in freshwater and the Baltic Sea, and through application of the new North Atlantic salinity–boron relationship (Lee et al., 2010), resulted in no significant difference in the internal consistency. [less ▲]

Detailed reference viewed: 26 (0 ULg)
Full Text
Peer Reviewed
See detailDomain Decomposition Methods for Time-Harmonic Electromagnetic Waves with High Order Whitney Forms
Marsic, Nicolas ULg; Waltz, Caleb; Lee, Jin-Fa et al

in IEEE Transactions on Magnetics (2016), 52(3),

Classically, domain decomposition methods (DDM) for time-harmonic electromagnetic wave propagation problems make use of the standard, low order, Nédélec basis functions. This paper analyzes the ... [more ▼]

Classically, domain decomposition methods (DDM) for time-harmonic electromagnetic wave propagation problems make use of the standard, low order, Nédélec basis functions. This paper analyzes the convergence rate of DDM when higher order finite elements are used for both volume and interface discretizations, in particular when different orders are used in the volume and on the interfaces. [less ▲]

Detailed reference viewed: 38 (9 ULg)
Full Text
Peer Reviewed
See detailAlong-stream transport and transformation of dissolved organic matter in a large tropical river
Lambert, Thibault ULg; Teodoru, C. R.; Nyoni, F. C. et al

in Biogeosciences (2016), 13(9), 2727--2741

Large rivers transport considerable amounts of terrestrial dissolved organic matter (DOM) to the ocean. However, downstream gradients and temporal variability in DOM fluxes and characteristics are poorly ... [more ▼]

Large rivers transport considerable amounts of terrestrial dissolved organic matter (DOM) to the ocean. However, downstream gradients and temporal variability in DOM fluxes and characteristics are poorly studied at the scale of large river basins, especially in tropical areas. Here, we report longitudinal patterns in DOM content and composition based on absorbance and fluorescence measurements along the Zambezi River and its main tributary, the Kafue River, during two hydrological seasons. During high-flow periods, a greater proportion of aromatic and humic DOM was mobilized along rivers due to the hydrological connectivity with wetlands, while low-flow periods were characterized by lower DOM content of less aromaticity resulting from loss of connectivity with wetlands, more efficient degradation of terrestrial DOM and enhanced autochthonous productivity. Changes in water residence time due to contrasting water discharge were found to modulate the fate of DOM along the river continuum. Thus, high water discharge promotes the transport of terrestrial DOM downstream relative to its degradation, while low water discharge enhances the degradation of DOM during its transport. The longitudinal evolution of DOM was also strongly impacted by a hydrological buffering effect in large reservoirs in which the seasonal variability of DOM fluxes and composition was strongly reduced. [less ▲]

Detailed reference viewed: 12 (5 ULg)
Full Text
Peer Reviewed
See detailCombining microCT-based characterization with empirical modelling as a robust screening approach for the design of optimized CaP-containing scaffolds for progenitor cell-mediated bone formation.
Kerckhofs, G.; Chai, Y. C.; Luyten, F. P. et al

in Acta Biomaterialia (2016), 35

Biomaterials are a key ingredient to the success of bone tissue engineering (TE), which focuses on the healing of bone defects by combining scaffolds with cells and/or growth factors. Due to the widely ... [more ▼]

Biomaterials are a key ingredient to the success of bone tissue engineering (TE), which focuses on the healing of bone defects by combining scaffolds with cells and/or growth factors. Due to the widely variable material characteristics and patient-specificities, however, current bone TE strategies still suffer from low repeatability and lack of robustness, which hamper clinical translation. Hence, optimal TE construct (i.e. cells and scaffold) characteristics are still under debate. This study aimed to reduce the material-specific variability for cell-based construct design, avoiding trial-and-error, by combining microCT characterization and empirical modelling as an innovative and robust screening approach. Via microCT characterization we have built a quantitative construct library of morphological and compositional properties of six CE approved CaP-based scaffolds (CopiOs(R), BioOss, Integra Mozaik, chronOS Vivify, MBCP and ReproBone), and of their bone forming capacity and in vivo scaffold degradation when combined with human periosteal derived cells (hPDCs). The empirical model, based on the construct library, allowed identification of the construct characteristics driving optimized bone formation, i.e. (a) the percentage of beta-TCP and dibasic calcium phosphate, (b) the concavity of the CaP structure, (c) the average CaP structure thickness and (d) the seeded cell amount (taking into account the seeding efficiency). Additionally, the model allowed to quantitatively predict the bone forming response of different hPDC-CaP scaffold combinations, thus providing input for a more robust design of optimized constructs and avoiding trial-and error. This could improve and facilitate clinical translation. STATEMENT OF SIGNIFICANCE: Biomaterials that support regenerative processes are a key ingredient for successful bone tissue engineering (TE). However, the optimal scaffold structure is still under debate. In this study, we have provided a useful innovative approach for robust screening of potential biomaterials or constructs (i.e. scaffolds seeded with cells and/or growth factors) by combining microCT characterization with empirical modelling. This novel approach leads to a better insight in the scaffold parameters influencing progenitor cell-mediated bone formation. Additionally, it serves as input for more controlled and robust design of optimized CaP-containing bone TE scaffolds. Hence, this novel approach could improve and facilitate clinical translation. [less ▲]

Detailed reference viewed: 15 (4 ULg)
Full Text
Peer Reviewed
See detailPolyphenols from Silybum marianum inhibit in vitro the oxidant response of equine neutrophils and myeloperoxidase activity.
Zholobenko, A.; Mouithys-Mickalad, Ange ULg; Modriansky, M. et al

in Journal of Veterinary Pharmacology & Therapeutics (2016)

A recent study showed that silymarin, a standardized extract of S. marianum might be used in the prevention of equine laminitis. We investigated the effects of quercetin and some compounds found in ... [more ▼]

A recent study showed that silymarin, a standardized extract of S. marianum might be used in the prevention of equine laminitis. We investigated the effects of quercetin and some compounds found in silymarin (silybin, taxifolin and dehydrosilybin) on reactive oxygen species (ROS) production and myeloperoxidase (MPO) release by stimulated equine neutrophils (PMNs) and on MPO activity. All compounds (tested between 100 nm and 100 mum) inhibited superoxide anion production by stimulated PMNs in a dose-dependent manner. Dehydrosilybin and quercetin inhibited superoxide production and MPO release from 10 mum. Classical MPO assay showed quercetin as the most potent inhibitor, followed by taxifolin, dehydrosilybin and silybin. SIEFED MPO assay highlighting the binding of tested compounds to MPO showed that only quercetin and taxifolin maintained an efficient inhibition above 90% at 10 mum. Altogether, our results showed a strong inhibition of PMN activation by planar compounds such as quercetin and dehydrosilybin and a strong inhibition of MPO activity by the smallest molecules, quercetin and taxifolin. In conclusion, the compounds from silymarin may be useful for modulating the oxidative response of PMNs, involved in the pathogenesis of laminitis, but further in vivo studies are needed. [less ▲]

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailLes croyances délétères des patients lombalgiques : revue narrative de la littérature
Demoulin, Christophe ULg; Roussel, Nathalie; Marty, Marc et al

in Revue Médicale de Liège (2016), 71(1), 40-46

Detailed reference viewed: 239 (20 ULg)
Full Text
See detailCompte rendu de "Plotin, Traité 12 (II, 4), Introduction, traduction, commentaires et notes par Elena Perdikouri"
Gavray, Marc-Antoine ULg

in Revue Philosophique de la France et de l'Etranger (2016), (2), 281-282

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailLa empresa social en Bélgica: diversidad de fuentes, modelos y campos
Huybrechts, Benjamin ULg

in Revista de la Academia (2016), 21

Este artículo está estructurado como sigue: la primera sección introductoria revisa las principales raíces históricas que han conduci- do a la emergencia de una diversidad de modelos relacionados con la ... [more ▼]

Este artículo está estructurado como sigue: la primera sección introductoria revisa las principales raíces históricas que han conduci- do a la emergencia de una diversidad de modelos relacionados con la empresa social y a la economía social en Bélgica. Enseguida, la segunda sección esboza los principales aspectos de esos modelos en relación a sus formas legales, tipos de misión social a las que se orientan, dinámicas de gobierno y recursos. En la tercera sección, esos modelos son ilustrados in diferentes campos de actividad, tanto establecidos como emergentes. Finalmente, la cuarta sección propone un análisis transversal de los principales tendencias y desafíos que enfrenta el desarrollo y coexisten- cia de los diferentes modelos. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailAgricultureIsLife or how to facilitate innovation in agriculture through multi-disciplinary research
Monty, Arnaud ULg; Garré, Sarah ULg; Bindelle, Jérôme ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2016)

Full Text
Peer Reviewed
See detailFinancial Impacts of Priority Swine Diseases to Pig Farmers in Red River and Mekong River Delta, Vietnam.
Pham, T. T. Hoa; Antoine-Moussiaux, Nicolas ULg; Grosbois, V. et al

in Transboundary and Emerging Diseases (2016)

A study was conducted between May 2013 and August 2014 in three provinces of Vietnam to investigate financial impacts of swine diseases in pig holdings in 2010-2013. The aim of the study was to quantify ... [more ▼]

A study was conducted between May 2013 and August 2014 in three provinces of Vietnam to investigate financial impacts of swine diseases in pig holdings in 2010-2013. The aim of the study was to quantify the costs of swine diseases at producer level in order to understand swine disease priority for monitoring at local level. Financial impacts of porcine reproductive and respiratory syndrome (PRRS), foot and mouth disease (FMD), and epidemic diarrhoea were assessed for 162 pig holders in two Red River Delta provinces and in one Mekong River Delta province, using data on pig production and swine disease outbreaks at farms. Losses incurred by swine diseases were estimated, including direct losses due to mortality (100% market value of pig before disease onset) and morbidity (abortion, delay of finishing stage), and indirect losses due to control costs (treatment, improving biosecurity and emergency vaccination) and revenue foregone (lower price in case of emergency selling). Financial impacts of swine diseases were expressed as percentage of gross margin of pig holding. The gross margin varied between pig farming groups (P < 0.0001) in the following order: large farm (USD 18 846), fattening farm (USD 7014) and smallholder (USD 2350). The losses per pig holding due to PRRS were the highest: 41% of gross margin for large farm, 38% for fattening farm and 63% for smallholder. Cost incurred by FMD was lower with 19%, 25% and 32% of gross margin of pig holding in large farm, fattening farm and smallholder, respectively. The cost of epidemic diarrhoea was the lowest compared to losses due to PRRS and FMD and accounted for around 10% of gross margin of pig holding in the three pig farming groups. These estimates provided critical elements on swine disease priorities to better inform surveillance and control at both national and local level. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailIn vitro and in vivo evaluation of drug-eluting microspheres designed for transarterial chemoembolization therapy
Wang, Y.; Molin, D.; Sevrin, Chantal ULg et al

in International Journal of Pharmaceutics (2016), 503

Detailed reference viewed: 20 (3 ULg)
Full Text
Peer Reviewed
See detailNetworks of prospective thoughts: the organisational role of emotion and its impact on well-being
Demblon, Julie ULg; D'Argembeau, Arnaud ULg

in Cognition & Emotion (2016), 30

Recent research has shown that many prospective thoughts are organised in networks of related events, but the relational dimensions that contribute to the formation of such networks are not fully ... [more ▼]

Recent research has shown that many prospective thoughts are organised in networks of related events, but the relational dimensions that contribute to the formation of such networks are not fully understood. Here, we investigated the organisational role of emotion by using cues of different valence for eliciting event networks. We found that manipulating the emotional valence of cues influenced the characteristics of events within networks, and that members of a network were more similar to each other on affective components than they were to members of other networks. Furthermore, a substantial proportion of events within networks were part of thematic clusters and cluster membership significantly modulated the impact of represented events on current well-being, in part through an intensification of the emotion felt when thinking about these events. These findings demonstrate that emotion contributes to the organisation of future thoughts in networks that can affect people’s well-being. [less ▲]

Detailed reference viewed: 83 (22 ULg)
Full Text
Peer Reviewed
See detailTECHNIQUE, DIFFICULTY, AND ACCURACY OF COMPUTED TOMOGRAPHY-GUIDED TRANSLAMINAR AND TRANSFORAMINAL LUMBOSACRAL EPIDURAL AND INTRAARTICULAR LUMBAR FACET JOINT INJECTIONS IN DOGS.
Liotta, Annalisa Pia ULg; Sandersen, Charlotte ULg; Couvreur, Thierry et al

in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association (2016), 57(2), 191-8

In human medicine, spinal pain and radiculopathy are commonly managed by computed tomography (CT)-guided facet joint injections and by transforaminal or translaminar epidural injections. In dogs, CT ... [more ▼]

In human medicine, spinal pain and radiculopathy are commonly managed by computed tomography (CT)-guided facet joint injections and by transforaminal or translaminar epidural injections. In dogs, CT-guided lumbosacral epidural or lumbar facet joint injections have not been described. The aim of this experimental, ex vivo, feasibility study was to develop techniques and to assess their difficulty and accuracy. Two canine cadavers were used to establish the techniques and eight cadavers to assess difficulty and accuracy. Contrast medium was injected and a CT scan was performed after each injection. Accuracy was assessed according to epidural or joint space contrast opacification. Difficulty was classified as easy, moderately difficult, or difficult, based on the number of CT scans needed to guide insertion of the needle. A total of six translaminar and five transforaminal epidural and 53 joint injections were performed. Translaminar injections had a high success rate (100%), were highly accurate (75%), and easy to perform (100%). Transforaminal injections had an moderately high success rate (75%), were accurate (75%), and moderately difficult to perform (100%). Success rate of facet joint injections was 62% and was higher for larger facet joints, such as L7-S1. Accuracy of facet joint injections ranged from accurate (37-62%) to highly accurate (25%) depending on the volume injected. In 77% of cases, injections were moderately difficult to perform. Possible complications of epidural and facet joint injections were subarachnoid and vertebral venous plexus puncture and periarticular spread, respectively. Further studies are suggested to evaluate in vivo feasibility and safety of these techniques. [less ▲]

Detailed reference viewed: 17 (4 ULg)
Full Text
Peer Reviewed
See detailBiotic homogenization can decrease landscape-scale forest multifunctionality
van der Plas, Fons; Manning, Pete; Soliveres, Santiago et al

in Proceedings of the National Academy of Sciences (2016), 113(13), 3557-62

Many experiments have shown that local biodiversity loss impairs the ability of ecosystems to maintain multiple ecosystem functions at high levels (multifunctionality). In contrast, the role of ... [more ▼]

Many experiments have shown that local biodiversity loss impairs the ability of ecosystems to maintain multiple ecosystem functions at high levels (multifunctionality). In contrast, the role of biodiversity in driving ecosystem multifunctionality at landscape scales remains unresolved. We used a comprehensive pan-European dataset, including 16 ecosystem functions measured in 209 forest plots across six European countries, and performed simulations to investigate how local plot-scale richness of tree species (α-diversity) and their turnover between plots (β-diversity) are related to landscape-scale multifunctionality. After accounting for variation in environmental conditions, we found that relationships between α-diversity and landscape-scale multifunctionality varied from positive to negative depending on the multifunctionality metric used. In contrast, when significant, relationships between β-diversity and landscape-scale multifunctionality were always positive, because a high spatial turnover in species composition was closely related to a high spatial turnover in functions that were supported at high levels. Our findings have major implications for forest management and indicate that biotic homogenization can have previously unrecognized and negative consequences for large-scale ecosystem multifunctionality. [less ▲]

Detailed reference viewed: 23 (6 ULg)
Full Text
Peer Reviewed
See detailDe la grammaire pure logique à la grammaire philosophique. La grammaire des concepts chez Wittgenstein
Gauvry, Charlotte ULg

in Bulletin d'Analyse Phénoménologique (2016)

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailBox search for the data mining of the key parameters of an industrial process
Louveaux, Quentin ULg; Mathei, Axel; Mathieu, Sébastien ULg

in Intelligent Data Analysis (2016), 20(6),

To increase their competitiveness, many industrial companies monitor their production process, collecting large amount of measurements. This paper describes a technique using this data to improve the ... [more ▼]

To increase their competitiveness, many industrial companies monitor their production process, collecting large amount of measurements. This paper describes a technique using this data to improve the performance of a monitored process. In particular we wish to find a set of rules, i.e. intervals on a reduced number of parameters, for which an output value is maximized. The model-free optimization problem to solve is to find a box, restricted on a limited amount of dimensions, with the maximum mean value of the included points. This article compares a machine learning-based heuristic to the solution computed by a mixed-integer linear program on real-life databases from steel and glass manufacturing. Computational results show that the heuristic obtains comparable solutions to the mixed integer linear approach. However, the exact approach is computationally too expensive to tackle real life databases. Results show that the restriction of five process parameters, on these databases, may improve the quality of the process by 50%. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailTypus melancholicus et mélancolie: synthèse théorique à partir d'un cas clinique
Englebert, Jérôme ULg; Stanghellini, Giovanni

in Encéphale (L') (2016), 42(1), 105-111

Objective: The objective of this paper is to propose, starting from the description of a clinical emblematic case, a theoretical synthesis of the work of phenomenological psychopathology dedicated to ... [more ▼]

Objective: The objective of this paper is to propose, starting from the description of a clinical emblematic case, a theoretical synthesis of the work of phenomenological psychopathology dedicated to melancholia and typus melancholicus (TM), a clinical concept that describes the premorbid personality vulnerable to major depression (“melancholia” for the psychopathological tradition). Method: This is phenomenological analysis of a case study of melancolia, of its premorbid personality and pathogenic triggering situation. We adopt two main phenomenological keys to understanding the develpment of melancholia : role-identity theory and desynchronization theory. The former understands melancholia as a disorder of identity triggered by the loss of the social role with which one has previously over-identifed. The latter sees melancholia as the effect of the desynchronisation from the social environment that further develops into an inhibition of the conative–affective dynamics of life. We present the case of Jonas (64 years old), whose mother (94 years old) recently died. Before his mother’s death, Jonas’ life was entirely orchestrated by the caring for his mother and synchronized in time with this (e.g., he used to go to her house every 4 hours, took all his meals with her, etc.). Jonas, in addition to being hyper-synchronized and hyper-syntonic, fulfills all diagnostic criteria for TM, including “orderliness”, “conscientiousness”, “hyper/heteronomia” and “intolerance of ambiguity”. TM’s attach a disproportioned importance to their social roles (or external representations of identity) at the expense of their own ego-identity. Results: The passage from pre-morbid personality to melancholia is triggered by the death of Jonas’ mother that entails a profound depersonalization. Desynchronization and role loss cause Jonas fall into this severe depersonalization, whose core feature is the feeling of the loss of feeling. Conclusions: This original contribution demonstrates a clinical case can contribute to the construction and refinement of theoretical and conceptual frameworks (like princeps Tellenbach's studies). Over-synchronized tempo and over-identification with social role are emblematically in this case the two sides of the same coin. A parallelism can be established between synchronization (with the mother) and respect for the role at the expense of own identity. The clinical case of Jonas highlights a conceptual bridge between the model of melancholia as loss of social role and the model of melancholia as desynchronization. [less ▲]

Detailed reference viewed: 111 (16 ULg)
Full Text
Peer Reviewed
See detailEffet inflammatoire des extraits de Cupressus sempervirens planté dans l’Est de l’Algérie : du modèle murin à la stimulation des cellules BEAS-2B par l’allergène majeur Cup s 1
Bouguenoun, Imene; De Pauw-Gillet, Marie-Claire ULg; Bensakhri, Z et al

in Revue Française d'Allergologie (2016), 56

Cupressus sempervirens est l’une des espèces les plus répandues en Algérie ayant une capacité allergénique très élevée. Nous avons étudié,d’abord, comment l’instillation nasale des différentes fractions ... [more ▼]

Cupressus sempervirens est l’une des espèces les plus répandues en Algérie ayant une capacité allergénique très élevée. Nous avons étudié,d’abord, comment l’instillation nasale des différentes fractions de l’extrait pollinique de cette espèce peut moduler la réponse immunitaire chez les souris, et, ensuite, la stimulation des cellules épithéliales bronchiques humaines (BEAS-2B) par l’allergène majeur, identifié par spectrométrie de masse et purifié par chromatographie échangeuse d’ions. La sensibilisation des souris a révélé, d’une part, une diminution du nombre de neutrophiles et une augmentation des éosinophiles, et, d’autre part, une augmentation significative du total cellulaire dans le liquide du lavage bronchoalvéolaire.L’étude histologique des poumons a montré une présence d’infiltrat inflammatoire et d’oedème péri-bronchique. La spectrométrie de masse nous a permis de mettre en évidence la présence de l’allergène majeur Cup s 1 dans toutes les fractions avec une présence spécifique du Cup s 3 et Cupa 1 dans la fraction 4. Cet allergène avait le potentiel pour stimuler la libération de l’IL-8 et l’IL-6 par la ligné cellulaire, BEAS-2B, in vitro d’une manière dose-dépendante [less ▲]

Detailed reference viewed: 32 (3 ULg)
Full Text
Peer Reviewed
See detail"Translating Multilayered Sensory Experience"
Bada, Valérie ULg; Pagnoulle, Christine ULg

in Palimpsestes (2016)

The powerful impact of the plays by African American playwright August Wilson largely relies on the way his words appeal to the senses, whether explicitly by calling upon the characters’ sensory ... [more ▼]

The powerful impact of the plays by African American playwright August Wilson largely relies on the way his words appeal to the senses, whether explicitly by calling upon the characters’ sensory experience or more indirectly through his use of syntactic rhythm, or indeed his specific modulation of AAVE. This article describes how the translators tried to create a French idiom that induces the same sensory impact on an audience and, at the same time, reflects the multilayered referentiality of the text. [less ▲]

Detailed reference viewed: 23 (10 ULg)
Full Text
Peer Reviewed
See detailHyperuricémie et risque potentiel de pathologie cardiovasculiare et rénale
Schils, Raphaël ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2016)

Besides the well accepted need to treat hyperuricemia associated with gout, some large observational studies and small prospective therapeutic trials have suggested that treating asymptomatic ... [more ▼]

Besides the well accepted need to treat hyperuricemia associated with gout, some large observational studies and small prospective therapeutic trials have suggested that treating asymptomatic hyperuricemia, especially by xanthine oxidase inhibition, the enzyme producing uric acid, could be beneficial for cardiovascular and renal risk prevention. This article discusses the literature about this promising approach, which, however, requests prospective validation. [less ▲]

Detailed reference viewed: 24 (4 ULg)
Full Text
Peer Reviewed
See detailCheatgrass is favored by warming but not CO2 enrichment in a semi-arid grassland
Blumenthal, Dana; Kray, Julie; Ortmans, William ULg et al

in Global Change Biology (2016), Early view

Elevated CO2 and warming may alter terrestrial ecosystems by promoting invasive plants with strong community and ecosystem impacts. Invasive plant responses to elevated CO2 and warming are difficult to ... [more ▼]

Elevated CO2 and warming may alter terrestrial ecosystems by promoting invasive plants with strong community and ecosystem impacts. Invasive plant responses to elevated CO2 and warming are difficult to predict, however, because of the many mechanisms involved, including modification of phenology, physiology, and cycling of nitrogen and water. Understanding the relative and interactive importance of these processes requires multifactor experiments under realistic field conditions. Here, we test how free-air CO2 enrichment (to 600 ppmv) and infrared warming (+1.5 °C day/3 °C night) influence a functionally and phenologically distinct invasive plant in semi-arid mixed-grass prairie. Bromus tectorum (cheatgrass), a fast-growing Eurasian winter annual grass, increases fire frequency and reduces biological diversity across millions of hectares in western North America. Across 2 years, we found that warming more than tripled B. tectorum biomass and seed production, due to a combination of increased recruitment and increased growth. These results were observed with and without competition from native species, under wet and dry conditions (corresponding with tenfold differences in B. tectorum biomass), and despite the fact that warming reduced soil water. In contrast, elevated CO2 had little effect on B. tectorum invasion or soil water, while reducing soil and plant nitrogen (N). We conclude that (1) warming may expand B. tectorum's phenological niche, allowing it to more successfully colonize the extensive, invasion-resistant northern mixed-grass prairie, and (2) in ecosystems where elevated CO2 decreases N availability, CO2 may have limited effects on B. tectorum and other nitrophilic invasive species. [less ▲]

Detailed reference viewed: 22 (4 ULg)
Full Text
Peer Reviewed
See detailLes conséquences de la philosophie
Longo, Giuseppe; Cavazzini, Andrea ULg

in Glass Bead (2016)

Detailed reference viewed: 26 (1 ULg)
Full Text
Peer Reviewed
See detailThe Changing Landscape of Smoldering Multiple Myeloma: A European Perspective
CAERS, Jo ULg; de Larrea, Carlos; Leleu, Xavier et al

in Oncologist (2016), 21

Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder and bridges monoclonal gammopathyof undeterminedsignificance tomultiplemyeloma(MM), based on higher levels of circulating ... [more ▼]

Smoldering multiple myeloma (SMM) is an asymptomatic clonal plasma cell disorder and bridges monoclonal gammopathyof undeterminedsignificance tomultiplemyeloma(MM), based on higher levels of circulating monoclonal immunoglobulin and bone marrow plasmocytosis without end-organ damage. Until a Spanish study reported fewer MM-related events and better overall survival among patients with highrisk SMM treated with lenalidomide and dexamethasone, prior studies had failed to show improved survival with earlier intervention, although a reduction in skeletal-related events (without any impact on disease progression) has been described with bisphosphonate use. Risk factors have now been defined, and a subset of ultra-high-risk patients have been reclassified by the International Myeloma Working Group asMM, and thus will require optimalMMtreatment, based on biomarkers that identify patients with a.80% risk of progression. The number of these redefined patients is small (∼10%), but important to unravel, because their risk of progression to overt MM is substantial ($80% within 2 years). Patients with a high-risk cytogenetic profile are not yet considered for early treatment, because groups are heterogeneous and risk factors other than cytogenetics are deemed to weight higher. Because patients with ultra-highrisk SMM are now considered as MMand may be treated as such, concerns exist that earlier therapy may increase the risk of selecting resistant clones and induce side effects and costs. Therefore, an even more accurate identification of patients who would benefit from interventions needs to be performed, and clinical judgment and careful discussion of pros and cons of treatment initiation needs to be undertaken. For the greater majority ofSMMpatients, the standard of care remains observation until development of symptomatic MM occurs, encouraging participation in ongoing and upcoming SMM/early MM clinical trials, as well as consideration of bisphosphonate use in patients with early bone loss. [less ▲]

Detailed reference viewed: 132 (10 ULg)
Full Text
Peer Reviewed
See detailThe unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
Figueroa Yévenes, Maximiliano ULg; Sleutel, Mike; Vandevenne, Marylène ULg et al

in Journal of structural biology (2016)

Despite impressive successes in protein design, designing a well-folded protein of more 100 amino acids de novo remains a formidable challenge. Exploiting the promising biophysical features of the ... [more ▼]

Despite impressive successes in protein design, designing a well-folded protein of more 100 amino acids de novo remains a formidable challenge. Exploiting the promising biophysical features of the artificial protein Octarellin V, we improved this protein by directed evolution, thus creating a more stable and soluble protein: Octarellin V.1. Next, we obtained crystals of Octarellin V.1 in complex with crystallization chaperons and determined the tertiary structure. The experimental structure of Octarellin V.1 differs from its in silico design: the (alphabetaalpha) sandwich architecture bears some resemblance to a Rossman-like fold instead of the intended TIM-barrel fold. This surprising result gave us a unique and attractive opportunity to test the state of the art in protein structure prediction, using this artificial protein free of any natural selection. We tested 13 automated webservers for protein structure prediction and found none of them to predict the actual structure. More than 50% of them predicted a TIM-barrel fold, i.e. the structure we set out to design more than 10years ago. In addition, local software runs that are human operated can sample a structure similar to the experimental one but fail in selecting it, suggesting that the scoring and ranking functions should be improved. We propose that artificial proteins could be used as tools to test the accuracy of protein structure prediction algorithms, because their lack of evolutionary pressure and unique sequences features. [less ▲]

Detailed reference viewed: 16 (3 ULg)
Full Text
Peer Reviewed
See detailDistributions and Sea-to-air Fluxes of Nitrous Oxide in the South China Sea and the West Philippines Sea
Tseng, Hsiao-Chun; Chen, Chen-Tung Arthur; Borges, Alberto ULg et al

in Deep-Sea Research Part I, Oceanographic Research Papers (2016), 115

Abstract Approximately 600 water samples from the South China Sea (SCS) and 250 water samples from the West Philippines Sea (WPS) were collected during seven cruises from August 2003 to July 2007 to ... [more ▼]

Abstract Approximately 600 water samples from the South China Sea (SCS) and 250 water samples from the West Philippines Sea (WPS) were collected during seven cruises from August 2003 to July 2007 to determine nitrous oxide (N2O) distributions between the surface and a maximum depth of 4250 m. In the SCS, the average surface \{N2O\} concentration exceeded the atmospheric equilibrium concentration (on average 132 ± 23%); however in the WPS, the surface \{N2O\} concentration was lower than the atmospheric equilibrium concentration (on average 90 ± 22%). The \{N2O\} concentration reached a maximum (~23 nmol L−1) in the \{WPS\} at 800–1000 m, and (~28 nmol L−1) at a shallower depth of around 600–800 m in the SCS, owing to vertical mixing and intensive upwelling in the SCS. In the SCS, the surface \{N2O\} concentration was 7.59 ± 1.32 nmol L−1 and the calculated sea-to-air flux was 5.5 ± 3.9 μmol m−2 d−1. The surface \{N2O\} concentration in the WPS, 5.19 ± 1.26 nmol L−1, was lower than that in the SCS. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailLignin degradation and stability: Volatile Organic Compounds (VOCs) analysis throughout processing
Sallem-Idrissi, N.; Vanderghem, C.; Pacary, T. et al

in Polymer Degradation and Stability (2016), 130

This work investigates the Volatile Organic Compounds (VOCs) emissions during the processing of composite of polyamide 6 (PA) bio-filled with technical lignin. This is of prime interest as volatile ... [more ▼]

This work investigates the Volatile Organic Compounds (VOCs) emissions during the processing of composite of polyamide 6 (PA) bio-filled with technical lignin. This is of prime interest as volatile phenolic structural monomers issued from lignin could penetrate the human organism and cause undesirable health damages. A special attention is given to the measurement of formaldehyde as it is known to be a human carcinogen. Lignin main identified emission consists of a high level of formaldehyde and a large amount of complex substituted phenol and benzene, all representative and constitutive of its structure. Regarding the PA alone, it has been found that the predominant VOC product is ϵ-caprolactam. When filling PA6 with lignin, the emitted VOCs associated to this filler are mainly produced during the extrusion while, only traces are detected during the injection process. Formaldehyde emission level is three times higher during the injection than during the extrusion. Phenols and some remaining reactants used during industrial cellulosic extraction process are identified. Regarding the value of the Short-Term Exposure Limit (STEL), suitable industrial process, safety and hygiene rules must be adopted. © 2016 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 13 (2 ULg)
Full Text
Peer Reviewed
See detailAn age-calibrated definition of chronic kidney disease: Rationale and benefits.
DELANAYE, Pierre ULg; Glassock, Richard; Pottel, H et al

in Clinical Biochemist. Reviews (2016), 37(1),

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailWeakening of Jupiter's main auroral emission during January 2014
Badman, S. V.; Bonfond, Bertrand ULg; Fujimoto, M. et al

in Geophysical Research Letters (2016), 43(3), 988-997

In January 2014 Jupiter's FUV main auroral oval decreased its emitted power by 70% and shifted equatorward by ∼1°. Intense, low-latitude features were also detected. The decrease in emitted power is ... [more ▼]

In January 2014 Jupiter's FUV main auroral oval decreased its emitted power by 70% and shifted equatorward by ∼1°. Intense, low-latitude features were also detected. The decrease in emitted power is attributed to a decrease in auroral current density rather than electron energy. This could be caused by a decrease in the source electron density, an order of magnitude increase in the source electron thermal energy, or a combination of these. Both can be explained either by expansion of the magnetosphere or by an increase in the inward transport of hot plasma through the middle magnetosphere and its interchange with cold flux tubes moving outward. In the latter case the hot plasma could have increased the electron temperature in the source region and produced the intense, low-latitude features, while the increased cold plasma transport rate produced the shift of the main oval. © 2016. The Authors. [less ▲]

Detailed reference viewed: 11 (3 ULg)
Full Text
Peer Reviewed
See detailTreacher Collins syndrome: a clinical and molecular study based on a large series of patients.
Vincent, Marie; Genevieve, David; Ostertag, Agnes et al

in Genetics in medicine : official journal of the American College of Medical Genetics (2016), 18(1), 49-56

PURPOSE: Treacher Collins/Franceschetti syndrome (TCS; OMIM 154500) is a disorder of craniofacial development belonging to the heterogeneous group of mandibulofacial dysostoses. TCS is classically ... [more ▼]

PURPOSE: Treacher Collins/Franceschetti syndrome (TCS; OMIM 154500) is a disorder of craniofacial development belonging to the heterogeneous group of mandibulofacial dysostoses. TCS is classically characterized by bilateral mandibular and malar hypoplasia, downward-slanting palpebral fissures, and microtia. To date, three genes have been identified in TCS:,TCOF1, POLR1D, and POLR1C. METHODS: We report a clinical and extensive molecular study, including TCOF1, POLR1D, POLR1C, and EFTUD2 genes, in a series of 146 patients with TCS. Phenotype-genotype correlations were investigated for 19 clinical features, between TCOF1 and POLR1D, and the type of mutation or its localization in the TCOF1 gene. RESULTS: We identified 92/146 patients (63%) with a molecular anomaly within TCOF1, 9/146 (6%) within POLR1D, and none within POLR1C. Among the atypical negative patients (with intellectual disability and/or microcephaly), we identified four patients carrying a mutation in EFTUD2 and two patients with 5q32 deletion encompassing TCOF1 and CAMK2A in particular. Congenital cardiac defects occurred more frequently among patients with TCOF1 mutation (7/92, 8%) than reported in the literature. CONCLUSION: Even though TCOF1 and POLR1D were associated with extreme clinical variability, we found no phenotype-genotype correlation. In cases with a typical phenotype of TCS, 6/146 (4%) remained with an unidentified molecular defect.Genet Med 18 1, 49-56. [less ▲]

Detailed reference viewed: 7 (1 ULg)
Full Text
Peer Reviewed
See detailDrivers of earthworm incidence and abundance across European forests
De Wandeler, Hans; Sousa-Silva, Rita; Ampoorter, Evy et al

in Soil Biology & Biochemistry (2016), 99

Earthworms have a significant influence on the structure, composition and functioning of forest ecosystems, but in spite of their role as ecosystem engineers, little is known on the factors controlling ... [more ▼]

Earthworms have a significant influence on the structure, composition and functioning of forest ecosystems, but in spite of their role as ecosystem engineers, little is known on the factors controlling their distribution across European forests. Optimised sampling techniques, as well as more advanced statistical tools and geographical information systems have facilitated studies at the landscape scale. But these, and even larger-scale studies, are scarce due to data limitations, taxonomic inconsistencies and practical issues in linking existing databases. In this continental-scale field-based study we used boosted regression tree modelling to identify and evaluate the relative importance of environmental factors explaining earthworm incidence (presence/absence) and abundance (density and biomass) in European forests. To parameterise our models earthworms were sampled in six forest landscapes along a latitudinal gradient from the boreal north to the Mediterranean south in spring or autumn of 2012, together with several environmental variables. Earthworms were sampled using a combined method of mustard extraction and hand sorting of litter and a soil monolith, after which they were weighed and identified to functional group (epigeic, endogeic and anecic). We found that litter- and soil-related variables best explained earthworm incidence and biomass in European forests, leaving only a minor role to climaterelated variables. Among the litter related variables, understory vegetation played an important role in explaining earthworm incidence and abundance. The relative importance of explanatory variables differed between models for incidence, density and biomass and between earthworm functional groups. Our results suggested that threshold values for soil C:N ratio, forest floor pH and understory plant biomass and plant nutrient concentrations have to be attained before earthworms can occur. Beyond these threshold values, variables like soil C:N ratio, tree litter C:P ratio and forest floor mass further explain earthworm biomass. Mechanisms behind these observations are discussed in the light of future earthworm distribution modelling at continental scale. [less ▲]

Detailed reference viewed: 17 (4 ULg)
Full Text
Peer Reviewed
See detailDulaglutide (LY-2189265) for the treatment of type 2 diabetes.
Scheen, André ULg

in Expert review of clinical pharmacology (2016), 9(3), 385-99

Dulaglutide is a new once-weekly glucagon-like peptide-1 receptor agonist for the management of hyperglycemia in adult patients with type 2 diabetes. It stimulates dose-dependent insulin secretion and ... [more ▼]

Dulaglutide is a new once-weekly glucagon-like peptide-1 receptor agonist for the management of hyperglycemia in adult patients with type 2 diabetes. It stimulates dose-dependent insulin secretion and reduces glucagon secretion, both in a glucose-dependent manner. Efficacy on blood glucose control and safety were demonstrated in the large AWARD program in type 2 diabetic patients treated with diet, metformin, dual oral therapy or insulin lispro with or without metformin, confirming findings of pilot studies in Caucasian patients and data in Japanese patients. Dulaglutide 1.5 mg once weekly was superior to metformin, sitagliptin, insulin glargine and exenatide twice daily, and non-inferior to liraglutide 1.8 mg once daily regarding the reduction in glycated hemoglobin. A modest but significant weight loss was consistently observed. Most frequent adverse events were transient and generally mild gastrointestinal disturbances. Clinical outcomes of dulaglutide will not be known until the large prospective cardiovascular outcome trial REWIND is complete. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailThe Medium is the Message. Olivier Schrauwen's ‘Arsène Schrauwen’ Beyond Expectations of Autobiography, Colonial History and the Graphic Novel
Crucifix, Benoît ULg; Meesters, Gert

in European Comic Art (2016), 9(1), 24-62

This article proposes a close reading of Olivier Schrauwen's Arsène Schrauwen, focusing on the various cultural discourses that it engages with, and particularly its ironical self-positioning within the ... [more ▼]

This article proposes a close reading of Olivier Schrauwen's Arsène Schrauwen, focusing on the various cultural discourses that it engages with, and particularly its ironical self-positioning within the field of comics. First of all, Schrauwen playfully questions the entrenchment of autobiography in the contemporary graphic novel by presenting a wholly fantasized adventure as biographical family history. This play with generic expectations is continued through Schrauwen’s reliance on the tropes of the adventure story and its figuration of the voyage. Arsène Schrauwen also draws on stereotypical images of both Belgium and the Belgian Congo and integrates them into a grotesque narrative so as to question the supposed unicity of the individual and colonial bodies. Last but not least, the book displays a highly self-reflexive approach to comics storytelling, building on a legacy from Flemish comics in order to play with reading conventions, graphic enunciation and abstraction, thereby thematising the perception of the main character. [less ▲]

Detailed reference viewed: 40 (6 ULg)
Full Text
Peer Reviewed
See detailInvestigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.
Mertens; Simon, Coraline ULg; Van Bossuyt et al

in Food & Chemical Toxicology (2016), 89

Detailed reference viewed: 11 (2 ULg)
Full Text
Peer Reviewed
See detailHighlights in migraine electrophysiology: are controversies just reflecting disease heterogeneity?
MAGIS, Delphine ULg; Lisicki Martinez, Marco ULg; Coppola, Gianluca

in Current Opinion in Neurology (2016), 29(3)

PURPOSE OF REVIEW: In migraine, the brain is 'hyperresponsive', which refers to a deficit of habituation to repeated sensory stimuli between attacks. This deficit normalizes in peri-ictal and ictal phases ... [more ▼]

PURPOSE OF REVIEW: In migraine, the brain is 'hyperresponsive', which refers to a deficit of habituation to repeated sensory stimuli between attacks. This deficit normalizes in peri-ictal and ictal phases. A decreased cortical preactivation of thalamo-cortical origin and an impaired intracortical inhibition are probably involved in its pathophysiology. RECENT FINDINGS: The reality of a habituation deficit of visual evoked potentials, a neurophysiological 'hallmark' of interictal migraine, has been questioned. Blinding may be an issue, but some genetic, environmental, or behavioural differences could also exist between populations. A habituation deficit is found interictally in other sensory modalities, and strongly depends on the time of the recordings within the migraine cycle. An impaired thalamocortical drive is demonstrated in interictal phase, and normalizes in ictal phase as well as in chronic migraine, where a strength enhancement of primary cortical activation is observed. An interictal dysexcitability, of subcortical or primary cortical origin, is suggested by magnetic stimulation. These phenomena could occur in varying degrees depending on patients and on the migraine cycle, and account for the heterogeneity of electrophysiological results. SUMMARY: Finding a reliable electrophysiological biomarker for such a multifaceted and cycling disease as migraine is still a challenge. A better standardization of protocols would be worthwhile. [less ▲]

Detailed reference viewed: 16 (4 ULg)
Full Text
Peer Reviewed
See detailMaximum Entropy Kernels for System Identification
Carli, Francesca Paola ULg; Chen, Tianshi; Ljung, Lennart

in IEEE Transactions on Automatic Control (2016)

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailElectric Field Control of Jahn-Teller Distortions in Bulk Perovskites
Varignon, Julien ULg; Bristowe, Nicholas ULg; Ghosez, Philippe ULg

in Physical Review Letters (2016), 116

The Jahn-Teller distortion, by its very nature, is often at the heart of the various electronic properties displayed by perovskites and related materials. Despite the Jahn-Teller mode being nonpolar, we ... [more ▼]

The Jahn-Teller distortion, by its very nature, is often at the heart of the various electronic properties displayed by perovskites and related materials. Despite the Jahn-Teller mode being nonpolar, we devise and demonstrate, in the present Letter, an electric field control of Jahn-Teller distortions in bulk perovskites. The electric field control is enabled through an anharmonic lattice mode coupling between the Jahn-Teller distortion and a polar mode. We confirm this coupling and quantify it through first-principles calculations. The coupling will always exist within the Pb21m space group, which is found to be the favored ground state for various perovskites under sufficient tensile epitaxial strain. Intriguingly, the calculations reveal that this mechanism is not only restricted to Jahn-Teller active systems, promising a general route to tune or induce novel electronic functionality in perovskites as a whole. [less ▲]

Detailed reference viewed: 16 (5 ULg)
Full Text
Peer Reviewed
See detailMaximum entropy properties of discrete-time first-order stable spline kernel
Chen, Tianshi; Ardeshiri, Tohid; Carli, Francesca Paola ULg et al

in Automatica (2016), 66

Detailed reference viewed: 50 (2 ULg)
Full Text
Peer Reviewed
See detailSafety, efficacy and clinical generalization of the STAR protocol: a retrospective analysis
Stewart, K. W.; Pretty, C. G.; Tomlinson, H. et al

in Annals of Intensive Care (2016), 6(1),

Background: The changes in metabolic pathways and metabolites due to critical illness result in a highly complex and dynamic metabolic state, making safe, effective management of hyperglycemia and ... [more ▼]

Background: The changes in metabolic pathways and metabolites due to critical illness result in a highly complex and dynamic metabolic state, making safe, effective management of hyperglycemia and hypoglycemia difficult. In addition, clinical practices can vary significantly, thus making GC protocols difficult to generalize across units.The aim of this study was to provide a retrospective analysis of the safety, performance and workload of the stochastic targeted (STAR) glycemic control (GC) protocol to demonstrate that patient-specific, safe, effective GC is possible with the STAR protocol and that it is also generalizable across/over different units and clinical practices. Methods: Retrospective analysis of STAR GC in the Christchurch Hospital Intensive Care Unit (ICU), New Zealand (267 patients), and the Gyula Hospital, Hungary (47 patients), is analyzed (2011–2015). STAR Christchurch (BG target 4.4–8.0 mmol/L) is also compared to the Specialized Relative Insulin and Nutrition Tables (SPRINT) protocol (BG target 4.4–6.1 mmol/L) implemented in the Christchurch Hospital ICU, New Zealand (292 patients, 2005–2007). Cohort mortality, effectiveness and safety of glycemic control and nutrition delivered are compared using nonparametric statistics. Results: Both STAR implementations and SPRINT resulted in over 86 % of time per episode in the blood glucose (BG) band of 4.4–8.0 mmol/L. Patients treated using STAR in Christchurch ICU spent 36.7 % less time on protocol and were fed significantly more than those treated with SPRINT (73 vs. 86 % of caloric target). The results from STAR in both Christchurch and Gyula were very similar, with the BG distributions being almost identical. STAR provided safe GC with very few patients experiencing severe hypoglycemia (BG < 2.2 mmol/L, <5 patients, 1.5 %). Conclusions: STAR outperformed its predecessor, SPRINT, by providing higher nutrition and equally safe, effective control for all the days of patient stay, while lowering the number of measurements and interventions required. The STAR protocol has the ability to deliver high performance and high safety across patient types, time, clinical practice culture (Christchurch and Gyula) and clinical resources. © 2016, Stewart et al. [less ▲]

Detailed reference viewed: 11 (3 ULg)
Full Text
Peer Reviewed
See detailNew Insight on the Performance of Equity Long/short Investment Styles
Fays, Boris ULg; Hübner, Georges ULg; Lambert, Marie ULg

in Bankers, Markets, Investors (2016), 140(January-February), 34-45

Long-short equity strategies have recently generated exceptional performance raising a set of concerns about the strategies’ propensity to deliver alpha or beta. This paper revisits the performance of ... [more ▼]

Long-short equity strategies have recently generated exceptional performance raising a set of concerns about the strategies’ propensity to deliver alpha or beta. This paper revisits the performance of equity long-short hedge funds across investments styles. We first categorize individual hedge funds with regard to their size and/or value factor investing along the generalization of Sharpe (1992) style analysis. Style weights on size and value factors are used to split the equity long-short universe in 5x5 hedge fund style portfolios. To analyze the performance of each style, we consider two sets of innovative factors. First, we apply sequential Fama-French model of Lambert, Fays and Hübner (2015). Besides, to captures downside and extreme risk embedded in hedge fund strategies we augment the model with the co-skewness and co-kurtosis factors developed by Lambert and Hübner (2013). Under this framework, we perform cross-sectional performance analyses of individual hedge funds as well as time-series analysis on the hedge fund style broad category. Our contributions are threefold; first, our alternative framework significantly improves the explanatory power of the multi-factor model in the context of long-short equity funds, second, considering higher-moment factors aim to capture part of the abnormal return of the downside and extreme risk exposures taken by a fund manager, and finally, long-short equity hedge funds are, to some extent, less exposed to small capitalisation stocks than expected and instead rather prefer higher momentum levels in their strategies. [less ▲]

Detailed reference viewed: 68 (17 ULg)
Full Text
Peer Reviewed
See detailComment j'explore le malaise du nourrisson
Zambelli, Laura ULg; Battisti, Oreste ULg

in Revue Médicale de Liège (2016), 71

Detailed reference viewed: 47 (3 ULg)
Full Text
Peer Reviewed
See detailPolytype Attainability in III-V Semiconductor Nanowires
Johansson, J.; Zanolli, Zeila ULg; Dick, K. A.

in Crystal Growth & Design (2016), 16(1), 371-379

We propose a model that explains the phenomenon of polytypism in metal particle-seeded III-V semiconductor nanowires. The model is based on classical nucleation theory, utilizing the axial next-nearest ... [more ▼]

We propose a model that explains the phenomenon of polytypism in metal particle-seeded III-V semiconductor nanowires. The model is based on classical nucleation theory, utilizing the axial next-nearest-neighbor Ising (ANNNI) model to account for interlayer interaction up to the third nearest-neighboring layer. We investigate the limits of polytypism by varying the ANNNI interaction parameters. These calculations lead to attainability diagrams, which show the regions in interaction energy space where certain polytypes can be attained given that the supersaturation is precisely tuned. We calculate the values of the ANNNI interaction parameters for six common III-V materials from first principles by means of the projector-augmented wave method. We discuss our calculated values in view of previous results. Using these calculated values in our nucleation model, our analysis suggests that besides the commonly observed 3C (zinc blende) and 2H (wurtzite) polytypes the higher order polytypes 4H and 6H can also be attained, in agreement with experimental observations. © 2015 American Chemical Society. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailInterobserver agreement for the ATS/ERS/JRS/ALAT criteria for a UIP pattern on CT.
Walsh, Simon L. F.; Calandriello, Lucio; Sverzellati, Nicola et al

in Thorax (2016), 71(1), 45-51

OBJECTIVES: To establish the level of observer variation for the current ATS/ERS/JRS/ALAT criteria for a diagnosis of usual interstitial pneumonia (UIP) on CT among a large group of thoracic radiologists ... [more ▼]

OBJECTIVES: To establish the level of observer variation for the current ATS/ERS/JRS/ALAT criteria for a diagnosis of usual interstitial pneumonia (UIP) on CT among a large group of thoracic radiologists of varying levels of experience. MATERIALS AND METHODS: 112 observers (96 of whom were thoracic radiologists) categorised CTs of 150 consecutive patients with fibrotic lung disease using the ATS/ERS/JRS/ALAT CT criteria for a UIP pattern (3 categories--UIP, possibly UIP and inconsistent with UIP). The presence of honeycombing, traction bronchiectasis and emphysema was also scored using a 3-point scale (definitely present, possibly present, absent). Observer agreement for the UIP categorisation and for the 3 CT patterns in the entAUe observer group and in subgroups stratified by observer experience, were evaluated. RESULTS: Interobserver agreement across the diagnosis category scores among the 112 observers was moderate, ranging from 0.48 (IQR 0.18) for general radiologists to 0.52 (IQR 0.20) for thoracic radiologists of 10-20 years' experience. A binary score for UIP versus possible or inconsistent with UIP was examined. Observer agreement for this binary score was only moderate. No significant differences in agreement levels were identified when the CTs were stratified according to multidisciplinary team (MDT) diagnosis or patient age or when observers were categorised according to experience. Observer agreement for each of honeycombing, traction bronchiectasis and emphysema were 0.59+/-0.12, 0.42+/-0.15 and 0.43+/-0.18, respectively. CONCLUSIONS: Interobserver agreement for the current ATS/ERS/JRS/ALAT CT criteria for UIP is only moderate among thoracic radiologists, AUrespective of theAU experience, and did not vary with patient age or the MDT diagnosis. [less ▲]

Detailed reference viewed: 19 (4 ULg)
Full Text
Peer Reviewed
See detailEffects of Dairy Products Consumption on Health: Benefits and Beliefs-A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
Rozenberg, Serge; Body, Jean-Jacques; Bruyère, Olivier ULg et al

in Calcified Tissue International (2016), 98(1), 1-17

Dairy products provide a package of essential nutrients that is difficult to obtain in low-dairy or dairy-free diets, and for many people it is not possible to achieve recommended daily calcium intakes ... [more ▼]

Dairy products provide a package of essential nutrients that is difficult to obtain in low-dairy or dairy-free diets, and for many people it is not possible to achieve recommended daily calcium intakes with a dairy-free diet. Despite the established benefits for bone health, some people avoid dairy in their diet due to beliefs that dairy may be detrimental to health, especially in those with weight management issues, lactose intolerance, osteoarthritis, rheumatoid arthritis, or trying to avoid cardiovascular disease. This review provides information for health professionals to enable them to help their patients make informed decisions about consuming dairy products as part of a balanced diet. There may be a weak association between dairy consumption and a possible small weight reduction, with decreases in fat mass and waist circumference and increases in lean body mass. Lactose intolerant individuals may not need to completely eliminate dairy products from their diet, as both yogurt and hard cheese are well tolerated. Among people with arthritis, there is no evidence for a benefit to avoid dairy consumption. Dairy products do not increase the risk of cardiovascular disease, particularly if low fat. Intake of up to three servings of dairy products per day appears to be safe and may confer a favourable benefit with regard to bone health. [less ▲]

Detailed reference viewed: 36 (20 ULg)
Full Text
Peer Reviewed
See detailMolecular detection of bovine noroviruses in Argentinean dairy calves: Circulation of a tentative new genotype
Ferragut, Fatima; Vega, Celina; Mauroy, Axel ULg et al

in Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (2016), 40

Detailed reference viewed: 24 (8 ULg)
Full Text
Peer Reviewed
See detailEfficient P- and Ag-doped titania for the photocatalytic degradation of waste water organic pollutants
Bodson, Céline ULg; Heinrichs, Benoît ULg; Tasseroul, Ludivine ULg et al

in Journal of Alloys & Compounds (2016), 682

In this work, physico-chemical properties and photocatalytic activity of three types of dried or dried and calcined TiO2 materials, synthesized by the cogelation method, were studied: (i) a pure TiO2 ... [more ▼]

In this work, physico-chemical properties and photocatalytic activity of three types of dried or dried and calcined TiO2 materials, synthesized by the cogelation method, were studied: (i) a pure TiO2 xerogel ; (ii) TiO2 xerogels doped with Ag ; (iii) TiO2 xerogels co-doped with Ag and P. The presence of silver nanoparticles was observed by transmission electron microscopy (TEM) and the oxidation state of silver after calcination was examined by temperature-programmed reduction (TPR) measurements. The physico-chemical properties of xerogels were characterized by X-ray diffraction (XRD), diffuse reflectance UV-Vis spectroscopy (DR UV-Vis) and from nitrogen adsorption-desorption isotherms. The photocatalytic activity of the samples was quantified for the p-nitrophenol degradation under visible light. [less ▲]

Detailed reference viewed: 93 (14 ULg)
Full Text
Peer Reviewed
See detailFlow cytometry community fingerprinting and amplicon sequencing for the assessment of landfill leachate cellulolytic bioaugmentation
Kinet, Romain ULg; Dzaomuho, Phidias; Baert, Jonathan ULg et al

in Bioresource Technology (2016)

Flow cytometry (FCM) is a high throughput single cell technology that is actually becoming widely used for studying phenotypic and genotypic diversity among microbial communities. This technology is ... [more ▼]

Flow cytometry (FCM) is a high throughput single cell technology that is actually becoming widely used for studying phenotypic and genotypic diversity among microbial communities. This technology is considered in this work for the assessment of a bioaugmentation treatment in order to enhance cellulolytic potential of landfill leachate. The experimental results reveal the relevant increase of leachate cellulolytic potential due to bioaugmentation. Cytometric monitoring of microbial dynamics along these assays is then realized. The Flow FP package is used to establish microbial samples fingerprint from initial 2D cytometry histograms. This procedure allows highlighting microbial communities' variation along the assays. Cytometric and 16S rRNA gene sequencing fingerprinting methods are then compared. The two approaches give same evidence about microbial dynamics throughout digestion assay. There are however a lack of significant correlation between cytometric and amplicon sequencing fingerprint at genus or species level. Same phenotypical profiles of microbiota during assays matched to several 16S rRNA gene sequencing ones. Flow cytometry fingerprinting can thus be considered as a promising routine on-site method suitable for the detection of stability/variation/disturbance of complex microbial communities involved in bioprocesses. [less ▲]

Detailed reference viewed: 22 (6 ULg)
Full Text
Peer Reviewed
See detailEmergent identity formation and the co-operative: Theory building in relation to alternative organizational forms
Nelson, Teresa; Nelson, Dylan; Huybrechts, Benjamin ULg et al

in Entrepreneurship and Regional Development (2016), 28(3-4), 286-309

How are identities of alternative forms of organization constructed and how does this process differ relative to normative forms socially expected? In this research we consider identity formation in co ... [more ▼]

How are identities of alternative forms of organization constructed and how does this process differ relative to normative forms socially expected? In this research we consider identity formation in co-operatives, a population of organizations allied globally through values and practices such as democratic participation, voluntary and open membership, and limited return to capital investment. As an extension of current thinking on identity formation in entrepreneurship and organizational theory, we use co-operatives to explore social expectations and institutional arrangements around form at the societal, population, and organizational levels using a population ecology framework. We develop a research agenda based on propositions that address specific features of identity formation in less typical forms of organization, including tensions with normative business expectations, engagement with identity audiences, embeddedness in networks and alliances, structural factors influencing identity, and identity ambiguity. [less ▲]

Detailed reference viewed: 131 (12 ULg)
Full Text
Peer Reviewed
See detailClassification of riparian forest species and health condition using multi-temporal and hyperspatial imagery from unmanned aerial system
Michez, Adrien ULg; Piégay, Hervé; Lisein, Jonathan ULg et al

in Environmental Monitoring and Assessment (2016), 188(3),

Riparian forests are critically endangered many anthropogenic pressures and natural hazards. The importance of riparian zones has been acknowledged by European Directives, involving multi-scale monitoring ... [more ▼]

Riparian forests are critically endangered many anthropogenic pressures and natural hazards. The importance of riparian zones has been acknowledged by European Directives, involving multi-scale monitoring. The use of this very high resolution and hyperspatial imagery in a multi-temporal approach is an emerging topic. The trend is reinforced by the recent and rapid growth of the use of the unmanned aerial system (UAS), which has prompted the development of innovative methodology. Our study proposes a methodological framework to explore how a set of multi-temporal images acquired during a vegetative period can differentiate some of the deciduous riparian forest species and their health conditions. More specifically, the developed approach intends to identify, through a process of variable selection, which variables derived from UAS imagery and which scale of image analysis are the most relevant to our objectives. The methodological framework is applied to two study sites to describe the riparian forest through two fundamental characteristics: the species composition and the health condition. These characteristics were selected not only because of their use as proxies for the riparian zone ecological integrity but also because of their use for river management. The comparison of various scales of image analysis identified the smallest OBIA objects (ca. 1 m²) as the most relevant scale. Variables derived from spectral information (bands ratio's) were identified as the most appropriate, followed by variables related to the vertical structure of the forest. Classification results show good overall accuracies for the species composition of the riparian forest (five classes, 79.5 and 84.1 % for Site 1 and Site 2). The classification scenario regarding the health condition of the black alders of the Site 1 performed the best (90.6 %). The quality of the classification models developed with a UAS-based, cost-effective, and semi-automatic approach competes successfully with those developed using more expensive imagery, such as multispectral and hyperspectral airborne imagery. The high overall accuracy results obtained by the classification of the diseased alders open the door to applications dedicated to monitoring of the health conditions of riparian forest. Our methodological framework will allow UAS users to manage large imagery metrics datasets derived from those dense time series. [less ▲]

Detailed reference viewed: 39 (13 ULg)
Full Text
Peer Reviewed
See detailHidden Markov Model-based population synthesis
Saadi, Ismaïl ULg; El Saeid Mustafa, Ahmed Mohamed ULg; Teller, Jacques ULg et al

in Transportation Research. Part B : Methodological (2016), 90

Micro-simulation travel demand and land use models require a synthetic population, which consists of a set of agents characterized by demographic and socio-economic attributes. Two main families of ... [more ▼]

Micro-simulation travel demand and land use models require a synthetic population, which consists of a set of agents characterized by demographic and socio-economic attributes. Two main families of population synthesis techniques can be distinguished: (a) fitting methods (iterative proportional fitting, updating) and (b) combinatorial optimization methods. During the last few years, a third outperforming family of population synthesis procedures has emerged, i.e., Markov process-based methods such as Monte Carlo Markov Chain (MCMC) simulations. In this paper, an extended Hidden Markov Model (HMM)-based approach is presented, which can serve as a better alternative than the existing methods. The approach is characterized by a great flexibility and efficiency in terms of data preparation and model training. The HMM is able to reproduce the structural configuration of a given population from an unlimited number of micro-samples and a marginal distribution. Only one marginal distribution of the considered population can be used as a boundary condition to “guide” the synthesis of the whole population. Model training and testing are performed using the Survey on the Workforce of 2013 and the Belgian National Household Travel Survey of 2010. Results indicate that the HMM method captures the complete heterogeneity of the micro-data contrary to standard fitting approaches. The method provides accurate results as it is able to reproduce the marginal distributions and their corresponding multivariate joint distributions with an acceptable error rate (i.e., SRSME=0.54 for 6 synthesized attributes). Furthermore, the HMM outperforms IPF for small sample sizes, even though the amount of input data is less than that for IPF. Finally, simulations show that the HMM can merge information provided by multiple data sources to allow good population estimates. [less ▲]

Detailed reference viewed: 43 (16 ULg)
Full Text
See detailPatterns of Loving: Erna Brodber, Nothing's Mat
Romdhani, Rebecca ULg

in SX Salon: A Small Axe Literary Platform (2016), 21

Detailed reference viewed: 13 (0 ULg)