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See detailRural resilience and the role of social capital among farmers in Kirundo Province, Northern Burundi
Minani, Bonaventure ULg; Rurema, Déo-Guide; Lebailly, Philippe ULg

in APSTRACT Applied Studies in Agribusiness and Commerce (2013), 7(2-3), 121-125

In Burundi, more than 90% of the active population is engaged in family agriculture, which plays a vital role in food production and constitutes more than 50% of the GDP. Before the civil war of 1993 ... [more ▼]

In Burundi, more than 90% of the active population is engaged in family agriculture, which plays a vital role in food production and constitutes more than 50% of the GDP. Before the civil war of 1993, Kirundo was deemed the "breadbasket of the country", as the region fed many parts of Burundi through growing particular foods such as legumes and cereals. Family farming was market-oriented. Kirundo alone includes 8 lakes which offer opportunities for field irrigation. Today, this region is the first province in Burundi which shows a high rate of malnutrition, as poverty has increased and a sharp 53.9 % decline in agricultural production has been witnessed between 1996 and 2009. The aim of this article is to analyse the role of social capital through the local association network in improving family agriculture and the resilience to climate change and conflict crisis. In this study, 73 farmers were surveyed in Kirundo province through means of a questionnaire, and the study was completed by collecting secondary data. Analysis of the data reveals that, despite recurrent droughts in that region which caused deaths due to famines and displacement of people to neighbouring countries such as Rwanda and Tanzania, 44% of the farmers who were surveyed were shown to have resilience to climate change. The analysis of data shows that these farmers were members of well organised local associations, and had learned about specific topics such as financial management, processing and storage of agricultural products and livestock. The social capital network positively influences their income and their resilience to climate change and conflict crisis. [less ▲]

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See detailHot electron production and diffuse excited states in C70, C82, and Sc3N@C80 characterized by angular-resolved photoelectron spectroscopy
Johansson, J. Olof; Bohl, Elvira; Henderson, Gordon G. et al

in Journal of Chemical Physics (2013), 139

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See detailNanosphere Lithography: A Powerful Method for the Controlled Manufacturing of Nanomaterials
Colson, Pierre ULg; Henrist, Catherine ULg; Cloots, Rudi ULg

in Journal of Nanomaterials (2013)

The never-ending race towards miniaturization of devices induced an intense research in the manufacturing processes of the components of those devices. However, the complexity of the process combined with ... [more ▼]

The never-ending race towards miniaturization of devices induced an intense research in the manufacturing processes of the components of those devices. However, the complexity of the process combined with high equipment costs makes the conventional lithographic techniques unfavorable for many researchers. Through years, nanosphere lithography (NSL) attracted growing interest due to its compatibility with wafer-scale processes as well as its potential to manufacture a wide variety of homogeneous one-, two-, or three-dimensional nanostructures. This method combines the advantages of both top-down and bottom-up approaches and is based on a two-step process: (1) the preparation of a colloidal crystal mask (CCM) made of nanospheres and (2) the deposition of the desired material through the mask. The mask is then removed and the layer keeps the ordered patterning of the mask interstices. Many groups have been working to improve the quality of the CCMs. Throughout this review, we compare the major deposition techniques to manufacture the CCMs (focusing on 2D polystyrene nanospheres lattices), with respect to their advantages and drawbacks. In traditional NSL, the pattern is usually limited to triangular structures. However, new strategies have been developed to build up more complex architectures and will also be discussed. [less ▲]

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See detailIntegration of photovoltaic cells in solar drying systems
Bennamoun, Lyes ULg

in Drying Technology (2013), 31(11), 1284-1296

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See detailAnalysis of gene expression in canine idiopathic pulmonary fibrosis
Krafft, Emilie ULg; Laurila, HP; peters, IR et al

in Veterinary Journal (2013)

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See detailComparison of Two Methods, UHPLC-UV and UHPLC-MS/MS, for the Quantification of Polyphenols in Cider Apple Juices
Verdu, Cindy ULg; Gatto, Julia; Freuze, Ingrid et al

in Molecules (2013), 18/9

Abstract: The aim of this study was to develop faster and more efficient phenotyping methods for in-depth genetic studies on cider apple progeny. The UHPLC chromatographic system was chosen to separate ... [more ▼]

Abstract: The aim of this study was to develop faster and more efficient phenotyping methods for in-depth genetic studies on cider apple progeny. The UHPLC chromatographic system was chosen to separate polyphenolic compounds, and quantifications were then simultaneously performed with a UV-PDA detector and an ESI-triple quadrupole mass analyzer (SRM mode). Both quantification methods were validated for 15 major compounds using two apple juice samples, on the basis of linearity, limits of detection and quantification, recovery and precision tests. The comparison between UV and SRM quantifications in 120 different samples of a cider apple progeny showed an excellent correlation for major compounds quantified with both methods. However, an overestimation was revealed for five compounds with the UV detector and the mass analyzer. Co-elution and matrix effects are discussed to explain this phenomenon. SRM methods should therefore be considered with restrictions in some cases for quantification measurements when several phenolic compounds are simultaneously quantified in complex matrices such as apple juices. For both methods, analyses were carried out over short periods of time while maintaining a high quality for the simultaneous quantification of phenolic compounds in apple juice. Each method is relevant for more in-depth genetic studies of the polyphenol content of apple juice. [less ▲]

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See detailIn vivo PET/CT in a human glioblastoma chicken chorioallantoic membrane model: A new tool for oncology and radiotracer development.
Warnock, Geoffrey; Turtoi, Andrei ULg; Blomme, Arnaud ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (2013), 54(10), 1-7

For many years the laboratory mouse has been used as the standard model for in vivo oncology research, particularly in the development of novel PET tracers, but the growth of tumors on chicken ... [more ▼]

For many years the laboratory mouse has been used as the standard model for in vivo oncology research, particularly in the development of novel PET tracers, but the growth of tumors on chicken chorioallantoic membrane (CAM) provides a more rapid, low cost and ethically sustainable alternative. For the first time, we demonstrate the feasibility of in vivo PET and CT imaging in a U87 glioblastoma tumor model on chicken chorioallantoic membrane (CAM), with the aim of applying this model for screening of novel PET tracers. Methods: U87 glioblastoma cells were implanted on the CAM at day 11 post-fertilization and imaged at day 18. A small animal imaging cell was used to maintain incubation and allow anesthesia using isoflurane. Radiotracers were injected directly into the exposed CAM vasculature. Sodium [18F]fluoride was used to validate the imaging protocol, demonstrating that image-degrading motion can be removed with anesthesia. Tumor glucose metabolism was imaged using [18F]fluorodeoxyglucose and tumor protein synthesis was imaged using 2-[18F]fluoro-L-tyrosine. Anatomical images were obtained by contrast enhanced CT, facilitating clear delineation of the tumor, delineation of tracer uptake in tumor versus embryo and accurate volume measurements. Results: PET imaging of tumor glucose metabolism and protein synthesis was successfully demonstrated in the CAM U87 glioblastoma model. Catheterization of CAM blood vessels facilitated dynamic imaging of glucose metabolism with [18F]fluorodeoxyglucose and demonstrated the ability to study PET tracer uptake over time in individual tumors, while CT imaging improved the accuracy of tumor volume measurements. Conclusion: In summary, we describe the novel application of PET/CT in the CAM tumor model, with optimization of typical imaging protocols. PET imaging in this valuable tumor model could prove particularly useful for rapid, high-throughput screening of novel radiotracers. [less ▲]

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See detailChanges in Effective Connectivity by Propofol Sedation
Gomez Jaramillo, Francisco Albeiro ULg; Phillips, Christophe ULg; Soddu, Andrea ULg et al

in PLoS ONE (2013), 8(8), 71370

Mechanisms of propofol-induced loss of consciousness remain poorly understood. Recent fMRI studies have shown decreases in functional connectivity during unconsciousness induced by this anesthetic agent ... [more ▼]

Mechanisms of propofol-induced loss of consciousness remain poorly understood. Recent fMRI studies have shown decreases in functional connectivity during unconsciousness induced by this anesthetic agent. Functional connectivity does not provide information of directional changes in the dynamics observed during unconsciousness. The aim of the present study was to investigate, in healthy humans during an auditory task, the changes in effective connectivity resulting from propofol induced loss of consciousness. We used Dynamic Causal Modeling for fMRI (fMRI-DCM) to assess how causal connectivity is influenced by the anesthetic agent in the auditory system. Our results suggest that the dynamic observed in the auditory system during unconsciousness induced by propofol, can result in a mixture of two effects: a local inhibitory connectivity increase and a decrease in the effective connectivity in sensory cortices. [less ▲]

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See detailApproximating Functions on a Mesh with Restricted Voronoï Diagrams
Nivoliers, Vincent ULg; Lévy, Bruno

in Computer Graphics Forum (2013), 32(5), 83-92

We propose a method that computes a piecewise constant approximation of a function defined on a mesh. The approximation is associated with the cells of a restricted Voronoï diagram. Our method optimizes ... [more ▼]

We propose a method that computes a piecewise constant approximation of a function defined on a mesh. The approximation is associated with the cells of a restricted Voronoï diagram. Our method optimizes an objective function measuring the quality of the approximation. This objective function depends on the placement of the samples that define the restricted Voronoï diagram and their associated function values. We study the continuity of the objective function, derive the closed-form expression of its derivatives and use them to design a numerical solution mechanism. The method can be applied to a function that has discontinuities, and the result aligns the boundaries of the Voronoï cells with the discontinuities. Some examples are shown, suggesting potential applications in image vectorization and compact representation of lighting. [less ▲]

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See detailCytokine and transcription factor expression by Aspergillus fumigatus-stimulated peripheral blood mononuclear cells in dogs with sino-nasal aspergillosis
Vanherberghen, Morgane; Bureau, F.; Peters, I.R. et al

in Veterinary Immunology and Immunopathology (2013), 154(3-4), 111-20

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See detailHerschel imaging and spectroscopy of the nebula around the luminous blue variable star WRAY 15-751
Vamvatira-Nakou, Chloi ULg; Hutsemekers, Damien ULg; Royer, P. et al

in Astronomy and Astrophysics (2013), 557

We have obtained far-infrared Herschel-PACS imaging and spectroscopic observations of the nebular environment of the luminous blue variable (LBV) WRAY 15-751. The far-infrared images clearly show that the ... [more ▼]

We have obtained far-infrared Herschel-PACS imaging and spectroscopic observations of the nebular environment of the luminous blue variable (LBV) WRAY 15-751. The far-infrared images clearly show that the main, dusty nebula is a shell of radius 0.5 pc and width 0.35 pc extending outside the Hα nebula. Furthermore, these images reveal a second, bigger and fainter dust nebula that is observed for the first time. Both nebulae lie in an empty cavity, very likely the remnant of the O-star wind bubble formed when the star was on the main sequence. The kinematic ages of the nebulae are calculated to be about 2 × 10^4 and 8 × 10^4 years, and we estimated that each nebula contains ~0.05 Msun of dust. Modeling of the inner nebula indicates a Fe-rich dust. The far-infrared spectrum of the main nebula revealed forbidden emission lines coming from ionized and neutral gas. Our study shows that the main nebula consists of a shell of ionized gas surrounded by a thin photodissociation region illuminated by an “average” early-B star. We derive the abundance ratios N/O = 1.0 ± 0.4 and C/O = 0.4 ± 0.2, which indicate a mild N/O enrichment. From both the ionized and neutral gas components we estimate that the inner shell contains 1.7 ± 0.6 Msun of gas. Assuming a similar dust-to-gas ratio for the outer nebula, the total mass ejected by WRAY 15-751 amounts to 4± 2 Msun. The measured abundances, masses and kinematic ages of the nebulae were used to constrain the evolution of the star and the epoch at which the nebulae were ejected. Our results point to an ejection of the nebulae during the red super-giant (RSG) evolutionary phase of an ~40 Msun star. The multiple shells around the star suggest that the mass-loss was not a continuous ejection but rather a series of episodes of extreme mass-loss. Our measurements are compatible with the recent evolutionary tracks computed for an ~40 Msun star with little rotation. They support the O–BSG–RSG–YSG–LBV filiation and the idea that high-luminosity and low-luminosity LBVs follow different evolutionary paths. [less ▲]

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See detailEnhanced basal lubrication and the contribution of the Greenland ice sheet to future sea-level rise
Shannon, S.; Payne, A.; Bartholomew, I. et al

in Proceedings of the National Academy of Sciences of the United States of America (2013), 110(49), 19719-19724

We assess the effect of enhanced basal sliding on the flow and mass budget of the Greenland ice sheet, using a newly developed parameterization of the relation between meltwater runoff and ice flow. A ... [more ▼]

We assess the effect of enhanced basal sliding on the flow and mass budget of the Greenland ice sheet, using a newly developed parameterization of the relation between meltwater runoff and ice flow. A wide range of observations suggest that water generated by melt at the surface of the ice sheet reaches its bed by both fracture and drainage through moulins. Once at the bed, this water is likely to affect lubrication, although current observations are insufficient to determine whether changes in subglacial hydraulics will limit the potential for the speedup of flow. An uncertainty analysis based on our best-fit parameterization admits both possibilities: continuously increasing or bounded lubrication. We apply the parameterization to four higher-order ice-sheet models in a series of experiments forced by changes in both lubrication and surface mass budget and determine the additional mass loss brought about by lubrication in comparison with experiments forced only by changes in surface mass balance. We use forcing from a regional climate model, itself forced by output from the European Centre Hamburg Model (ECHAM5) global climate model run under scenario A1B. Although changes in lubrication generate widespread effects on the flow and form of the ice sheet, they do not affect substantial net mass loss; increase in the ice sheet’s contribution to sea-level rise from basal lubrication is projected by all models to be no more than 5% of the contribution from surface mass budget forcing alone. [less ▲]

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See detailSensitivity and specificity of blood leukocyte counts as an indicator of mortality in horses after colic surgery
Salciccia, Alexandra ULg; Sandersen, Charlotte ULg; Grulke, Sigrid ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2013), 173(11),

The objectives of this study were to describe and relate perioperative changes in blood leukocyte counts to the outcome of surgical colic horses, determine a cut-off value in the early postoperative ... [more ▼]

The objectives of this study were to describe and relate perioperative changes in blood leukocyte counts to the outcome of surgical colic horses, determine a cut-off value in the early postoperative period to obtain an indicator of the outcome, and compare the obtained value to a validation population of horses. Fifty-three horses undergoing colic surgery were included in the descriptive part of the study. Total leukocyte counts were performed before, during and serially after surgery. A receiver operating characteristic analysis was performed on the leukocyte counts of 45 of these horses to determine a cut-off value for the outcome. The results obtained were validated on a second set of 50 horses that underwent colic surgery in similar conditions. The kinetics of blood leukocytes in survivors was higher than in non-survivors during the first days. Non-survivor horses were more likely to have at least one blood leukocyte count ≤3.9×103/mm3 between 28 and 60 hours after surgery than survivor horses. This cut-off value was confirmed in the validation population. These results suggest that routine values of blood leukocyte counts can be used as an additional prognostic indicator after colic surgery alongside other predictors previously associated with the outcome. [less ▲]

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See detailCombining shearography and interferometric fringe projection in a single device for complete control of industrial applications
Blain, Pascal ULg; Michel, Fabrice; Piron, Pierre ULg et al

in Optical Engineering : The Journal of the Society of Photo-Optical Instrumentation Engineers (2013), 52(8), 0841021-7

Non-contact optical measurement methods are essential tools in many industrial and research domains. A family of new non-contact optical measurement methods based on the polarization states splitting ... [more ▼]

Non-contact optical measurement methods are essential tools in many industrial and research domains. A family of new non-contact optical measurement methods based on the polarization states splitting technique and monochromatic light projection as a way to overcome ambient lighting for in-situ measurement has been developed. Recent works on a birefringent element, a Savart plate, allow to build a more flexible and robust interferometer. This interferometer is a multipurpose metrological device. On one hand the interferometer can be set in front of a CCD camera. This optical measurement system is called a shearography interferometer and allows to measure micro displacements between two states of the studied object under coherent lighting. On the other hand by producing and shifting multiple sinusoidal Young’s interference patterns with this interferometer, and using a CCD camera, it is possible to build a 3D structured light profilometer. [less ▲]

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See detailProbing Rapidly-Ionizing Super-Atom Molecular Orbitals in C60: A Computational and Femtosecond Photoelectron Spectroscopy Study
Mignolet, Benoît ULg; Johansson, Olof; Campbell, Eleanor E. B. et al

in Chemphyschem : A European Journal of Chemical Physics and Physical Chemistry (2013)

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See detailMacroporous poly(ionic liquid)s and poly(acrylamide)s monoliths from CO2-in-water emulsion templates stabilized by sugar-based surfactants
Boyère, Cédric ULg; Favrelle, Audrey; Léonard, Alexandre ULg et al

in Journal of Materials Chemistry A (2013), 1(29), 8479-8487

Highly interconnected poly(acrylamide) (PAM) and poly(vinylimidazolium) (PVIm) porous monoliths were templated by carbon 10 dioxide-in-water (CO2/W) high internal phase emulsions (HIPEs), a toxic-solvent ... [more ▼]

Highly interconnected poly(acrylamide) (PAM) and poly(vinylimidazolium) (PVIm) porous monoliths were templated by carbon 10 dioxide-in-water (CO2/W) high internal phase emulsions (HIPEs), a toxic-solvent free process. A range of sugar-based fluorinated surfactants prepared by chemoenzymatic synthesis were used as emulsifiers. Both the concentration and the structure of the surfactants, especially the length of their CO2-philic part and of their spacer between the sugar head and the tail, were found to strongly affect the cellular structure and morphology of the PAM polyHIPEs, i.e. the size of pores and cells. A mannose derivative bearing a chain ranging from 6 to 10 perfluorinated carbons and a long spacer emerged as the best stabilizer, leading to a porous monolith with average pores and 15 cells sizes (about 2.6 1m and 5-10 1m, respectively) among the lowest reported for polyHIPEs produced from CO2/W emulsions. The same template then served for the preparation of the first macroporous poly(ionic liquid)s (PILs) polyHIPE by using 1-vinyl-3- ethylimidazolium bromide as monomer. Shrinkage of the final material was prevented by adjusting the divinylimidazolium crosslinker content. The resulting low density polyHIPE exhibits small spherical cells (~5 1m) connected by numerous small pores (~2 1m), confirming that the CO2/W HIPE templating methodology based on fluorinated glycosurfactants is a technique of choice for the 20 preparation of macroporous PILs. [less ▲]

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See detailElectrografting onto ITO substrates of poly(thiophene)-based micelles decorated by acrylate groups
Ouhib, Farid ULg; Desbief, Simon; Lazzaroni, Roberto et al

in Polymer Chemistry (2013), 4(15), 4151-4161

We report on a simple process for the chemisorption of poly(thiophene)-based block copolymers onto ITO substrates. Two poly(thiophene) block copolymers functionalized by acrylates on the second block are ... [more ▼]

We report on a simple process for the chemisorption of poly(thiophene)-based block copolymers onto ITO substrates. Two poly(thiophene) block copolymers functionalized by acrylates on the second block are prepared by the Grignard Metathesis (GRIM) process. The first block is composed of poly(3-hexylthiophene) (P3HT) and the second block is either a polythiophene bearing an acrylate group on each monomer unit (PAcET), or a polythiophene bearing both acrylate and poly(ethylene glycol) side chains (P(AcET-co-PEGET)). After characterizing their macromolecular parameters and optical properties, we investigate their ability to self-assemble into micelles in DMF solutions. This solvent is required for the electrografting procedure that is used for strongly anchoring the polymer to ITO. These micelles are expected to be formed by a P3HT core and a PAcET or P(AcET-co-PEGET) shell. When PEG side chains are present in the second block, the copolymer nicely self-assembles into micelles decorated by acrylates. Cathodic polarization of ITO induces chemisorption and polymerization of acrylate groups, leading to an adherent organized film of poly(thiophene)-based micelles. The optical absorption spectra show that the electrografted polymer chains have a degree of π-electron conjugation similar to that of crystalline P3HT films. In the absence of the PEG chains, the copolymer does not organize into micelles, due to the low stabilizing ability of the second block in DMF. [less ▲]

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See detailReview of Computational Systems Biology of Cancer
Bullinger, Eric ULg; Schliemann, Monica

in BioMedical Engineering OnLine (2013), 12(1), 76

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See detailA Simplified Analytical Method for Estimating the Crushing Resistance of an Inclined Ship Side
Buldgen, Loïc ULg; Le Sourne, Hervé; Rigo, Philippe ULg

in Marine Structures (2013)

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See detailConventional tree height-diameter relationships significantly overestimate aboveground carbon stocks in the Central Congo Basin
Kearsley, E; de Haulleville, Thalès ULg; Hufkens, K et al

in Nature Communications (2013), 4

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See detailHigh angular resolution imaging and infrared spectroscopy of CoRoT candidates
Guenther, E. W.; Fridlund, M.; Alonso, R. et al

in Astronomy and Astrophysics (2013), 556

Context. Studies of transiting extrasolar planets are of key importance for understanding the nature of planets outside our solar system because their masses, diameters, and bulk densities can be measured ... [more ▼]

Context. Studies of transiting extrasolar planets are of key importance for understanding the nature of planets outside our solar system because their masses, diameters, and bulk densities can be measured. An important part of transit-search programmes is the removal of false-positives. In the case of the CoRoT space mission, the majority of the false-positives are removed by a detailed analysis of the light curves and by seeing-limited imaging in- and out-of-transit. However, the critical question is how many of the candidates that passed all these tests are false-positives. Such false-positives can be caused by eclipsing binaries, which are either related or unrelated to the targets. <BR /> Aims: For our study we selected 25 CoRoT candidates that have already been screened against false-positives using detailed analysis of the light curves and seeing-limited imaging, which has transits that are between 0.7 and 0.05% deep. Our aim is to search for companion candidates that had not been recognized in previous observations. <BR /> Methods: We observed 20 candidates with the adaptive optics imager NaCo and 18 with the high-resolution infrared spectrograph CRIRES. <BR /> Results: We found previously unknown stars within 2'' of the targets in seven of the candidates. All of these are too faint and too close to the targets to have been previously detected with seeing-limited telescopes in the optical. Our study thus leads to the surprising results that if we remove all candidates excluded by the sophisticated analysis of the light-curve, as well as carrying out deep imaging with seeing-limited telescopes, still 28-35% of the remaining candidates are found to possess companions that are bright enough to be false-positives. <BR /> Conclusions: Given that the companion candidates cluster around the targets and that the J - K colours are consistent with physical companions, we conclude that the companion candidates are more likely to be physical companions rather than unrelated field stars. Based on observations obtained at the European Southern Observatory at Paranal, Chile in programmes 282.C-5015A, 282.C-5015B, 282.C-5015C, 285.C-5045A, and 285.C-5045B, 086.C-0235A, 086.C-0235B, 088.C-0707A, 088.C-0707B, 090.C-0251A, 090.C-0251B, and 091.C-203(A).Appendices A and B are available in electronic form at <A href="http://www.aanda.org">http://www.aanda.org</A> [less ▲]

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See detailSpectral modelling of the α Virginis (Spica) binary system
Palate, Matthieu ULg; Koenigsberger, G.; Rauw, Grégor ULg et al

in Astronomy and Astrophysics (2013), 556

Context. The technique of matching synthetic spectra computed with theoretical stellar atmosphere models to the observations is widely used in deriving fundamental parameters of massive stars. When ... [more ▼]

Context. The technique of matching synthetic spectra computed with theoretical stellar atmosphere models to the observations is widely used in deriving fundamental parameters of massive stars. When applied to binaries, however, these models generally neglect the interaction effects present in these systems. <BR /> Aims: The aim of this paper is to explore the uncertainties in binary stellar parameters that are derived from single-star models. <BR /> Methods: Synthetic spectra that include the tidal perturbations and irradiation effects are computed for the binary system α Virginis (Spica) using our recently-developed CoMBiSpeC model. The synthetic spectra are compared to S/N ~ 2000 observations and optimum values of T[SUB]eff[/SUB] and log g are derived. <BR /> Results: The binary interactions have only a small effect on the strength of the photospheric absorption lines in Spica (<2% for the primary and <4% for the secondary). These differences are comparable to the uncertainties inherent to the process of matching synthetic spectra to the observations and thus the derived values of T[SUB]eff[/SUB] and log g are unaffected by the binary perturbations. On the other hand, the interactions do produce significant phase-dependent line profile variations in the primary star, leading to systematic distortions in the shape of its radial velocity curve. Migrating sub-features ("bumps") are predicted by our model to be present in the same photospheric lines as observed, and their appearance does not require any a priori assumptions regarding non-radial pulsation modes. Matching the strength of lines in which the most prominent "bumps" occur requires synthetic spectra computed with larger "microturbulence" than that required by other lines. [less ▲]

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See detailMultispectral simultaneous diagnosis of Saturn's aurorae throughout a planetary rotation
Lamy, L.; Prangé, R.; Pryor, W. et al

in Journal of Geophysical Research. Space Physics (2013), 118

From 27 to 28 January 2009, the Cassini spacecraft remotely acquired combined observations of Saturn's southern aurorae at radio, ultraviolet, and infrared wavelengths, while monitoring ion injections in ... [more ▼]

From 27 to 28 January 2009, the Cassini spacecraft remotely acquired combined observations of Saturn's southern aurorae at radio, ultraviolet, and infrared wavelengths, while monitoring ion injections in the middle magnetosphere from energetic neutral atoms. Simultaneous measurements included the sampling of a full planetary rotation, a relevant timescale to investigate auroral emissions driven by processes internal to the magnetosphere. In addition, this interval coincidentally matched a powerful substorm-like event in the magnetotail, which induced an overall dawnside intensification of the magnetospheric and auroral activity. We comparatively analyze this unique set of measurements to reach a comprehensive view of kronian auroral processes over the investigated timescale. We identify three source regions for the atmospheric aurorae, including a main oval associated with the bulk of Saturn Kilometric Radiation (SKR), together with polar and equatorward emissions. These observations reveal the coexistence of corotational and subcorototational dynamics of emissions associated with the main auroral oval. Precisely, we show that the atmospheric main oval hosts short-lived subcorotating isolated features together with a bright, longitudinally extended, corotating region locked at the southern SKR phase. We assign the substorm-like event to a regular, internally driven, nightside ion injection possibly triggered by a plasmoid ejection. We also investigate the total auroral energy budget, from the power input to the atmosphere, characterized by precipitating electrons up to 20 keV, to its dissipation through the various radiating processes. Finally, through simulations, we confirm the search-light nature of the SKR rotational modulation and we show that SKR arcs relate to isolated auroral spots. We characterize which radio sources are visible from the spacecraft and we estimate the fraction of visible southern power to a few percent. The resulting findings are discussed in the frame of pending questions as the persistence of a corotating field-aligned current system within a subcorotating magnetospheric cold plasma, the occurrence of plasmoid activity, and the comparison of auroral fluxes radiated at different wavelengths. [less ▲]

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See detailThe Size, Shape, Albedo, Density, and Atmospheric Limit of Transneptunian Object (50000) Quaoar from Multi-chord Stellar Occultations
Braga-Ribas, F.; Sicardy, B.; Ortiz, J. L. et al

in Astrophysical Journal (2013), 773

We present results derived from the first multi-chord stellar occultations by the transneptunian object (50000) Quaoar, observed on 2011 May 4 and 2012 February 17, and from a single-chord occultation ... [more ▼]

We present results derived from the first multi-chord stellar occultations by the transneptunian object (50000) Quaoar, observed on 2011 May 4 and 2012 February 17, and from a single-chord occultation observed on 2012 October 15. If the timing of the five chords obtained in 2011 were correct, then Quaoar would possess topographic features (crater or mountain) that would be too large for a body of this mass. An alternative model consists in applying time shifts to some chords to account for possible timing errors. Satisfactory elliptical fits to the chords are then possible, yielding an equivalent radius R [SUB]equiv[/SUB] = 555 ± 2.5 km and geometric visual albedo p[SUB]V[/SUB] = 0.109 ± 0.007. Assuming that Quaoar is a Maclaurin spheroid with an indeterminate polar aspect angle, we derive a true oblateness of \epsilon = 0.087^{+0.0268}_{-0.0175}, an equatorial radius of 569^{+24}_{-17} km, and a density of 1.99 ± 0.46 g cm[SUP]–3[/SUP]. The orientation of our preferred solution in the plane of the sky implies that Quaoar's satellite Weywot cannot have an equatorial orbit. Finally, we detect no global atmosphere around Quaoar, considering a pressure upper limit of about 20 nbar for a pure methane atmosphere. [less ▲]

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See detailBacterial mastitis in the Azawak zebu breed at the Sahelian experimental station in Toukounous (Niger): Identification and typing of Staphylococcus aureus
Issa Ibrahim, Abdoulkarim; Bada-Alambedji, Rlanatou; Duprez, Jean-Noel et al

in International Research Journal of Microbiology [=IRJM] (2013), 4(7), 168-178

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See detailMuscle fatigue experienced during maximal eccentric exercise is predictive of the plasma creatine kinase (CK) response
Hody, Stéphanie ULg; Rogister, Bernard ULg; Leprince, Pierre ULg et al

in Scandinavian Journal of Medicine & Science in Sports (2013), 23(4), 501-7

Unaccustomed eccentric exercise may cause skeletal muscle damage with an increase in plasma creatine kinase (CK) activity. Although the wide variability among individuals in CK response to standardized ... [more ▼]

Unaccustomed eccentric exercise may cause skeletal muscle damage with an increase in plasma creatine kinase (CK) activity. Although the wide variability among individuals in CK response to standardized lengthening contractions has been well described, the reasons underlying this phenomenon have not yet been understood. Therefore, this study investigated a possible correlation of the changes in muscle damage indirect markers after an eccentric exercise with the decline in muscle performance during the exercise. Twenty-seven healthy untrained male subjects performed three sets of 30 maximal isokinetic eccentric contractions of the knee extensors. The muscular work was recorded using an isokinetic dynamometer to assess muscle fatigue by means of various fatigue indices. Plasma CK activity, muscle soreness, and stiffness were measured before (pre) and one day after (post) exercise. The eccentric exercise bout induced significant changes of the three muscle damage indirect markers. Large intersubject variability was observed for all criteria measured. More interestingly, the log (CKpost/CKpre) and muscle stiffness appeared to be closely correlated with the relative work decrease (r = 0.84, r2 = 0.70 and r = 0.75, r2 = 0.56, respectively). This is the first study to propose that the muscle fatigue profile during maximal eccentric protocol could predict the magnitude of the symptoms associated with muscle damage in humans. [less ▲]

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See detailThe usefulness of outcrop analogue air permeameter measurements for analyzing aquifer heterogeneity: quantifying outcrop hydraulic conductivity and its spatial variability
Rogiers, Bart; Beerten, Koen; Smeekens, Tuur et al

in Hydrological Processes (2013)

Saturated hydraulic conductivity (K) is one of the most important parameters determining groundwater flow and contaminant transport in both unsaturated and saturated porous media. Although several well ... [more ▼]

Saturated hydraulic conductivity (K) is one of the most important parameters determining groundwater flow and contaminant transport in both unsaturated and saturated porous media. Although several well-established laboratory methods exist for determining K, in situ measurements of this parameter remain very complex and scale dependent. Often, the limited accessibility of subsurface sediments for sampling means an additional impediment to our ability to quantify subsurface K heterogeneity. One potential solution is the use of outcrops as analogues for subsurface sediments. This paper investigates the use of air permeameter measurements on outcrops of unconsolidated sediments to quantify K and its spatial heterogeneity on a broad range of sediment types. The Neogene aquifer in northern Belgium is used as a case study for this purpose. To characterize the variability in K, 511 small-scale air permeability measurements were performed on outcrop sediments representative over five of the aquifer’s lithostratigraphic units. From these measurements, outcrop-scale equivalent K tensors were calculated using numerical upscaling techniques. Validation of the air permeameter-based K values by comparison with laboratory constant head K measurements reveals a correlation of 0.93. Overall, the results indicate that hand-held air permeameters are very efficient and accurate tools to characterize saturated K, as well as its small-scale variability and anisotropy on a broad range of unconsolidated sediments. The studied outcrops further provided a qualitative understanding of aquifer hydrostratigraphy and quantitative estimates about K variability at the centimetre-scale to metre-scale. [less ▲]

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See detailMinimally-supervised learning of domain-specific causal relations using an open-domain corpus as knowledge base
Ittoo, Ashwin ULg; Bouma, Gosse

in Data & Knowledge Engineering (2013)

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See detailGenetic evaluation of calving ease for Walloon Holstein dairy cattle.
Vanderick, Sylvie ULg; Troch, Thibault ULg; Gillon, Alain et al

in Interbull Bulletin (2013), 47

Calving complications have an incidence on the economic profitability of dairy herds. In the Walloon Region of Belgium, calving ease data recording is being done on voluntary basis since 2000. This allows ... [more ▼]

Calving complications have an incidence on the economic profitability of dairy herds. In the Walloon Region of Belgium, calving ease data recording is being done on voluntary basis since 2000. This allows now the implementation of a genetic evaluation of Holstein dairy cattle addressing the need of dairy breeders to select bulls in order to reduce frequency of calving problems. Calving ease scores were analyzed using univariate animal linear models, which were fitted with the genetic correlation between direct and maternal additive genetic effects either estimated or constrained to zero. Variance components and related genetic parameters were estimated from a dataset including 33,155 calving records. Included in the models were fixed season effects, fixed herd effects and fixed sex of calf*age of dam classes*group of calvings interaction effects, random herd*year of calving effects, random maternal permanent environment effects, and random animal direct and maternal additive genetic effects. For both models, direct and maternal heritabilities for calving ease were about 8% and about 2%, respectively. Genetic correlation between direct and maternal additive effects was found to be non-significantly different from zero. So, an animal linear model with genetic correlation between direct and maternal effects constrained to zero was adopted for the routine genetic evaluation of calving ease for Walloon Holstein dairy cattle. This model was validated by Interbull in January 2013 and, since April 2013, the Walloon Region of Belgium has officially participated to the international MACE evaluation for calving traits. [less ▲]

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See detailEffects of eccentrically and concentrically biased training on mouse muscle phenotype
Hody, Stéphanie ULg; Lacrosse, Zoé ULg; Leprince, Pierre ULg et al

in Medicine & Science in Sports & Exercise (2013), 45(8), 1460-1468

Introduction: The molecular adaptations specifically induced by different muscle contraction types have only been partially elucidated. We previously demonstrated that eccentric contractions in human ... [more ▼]

Introduction: The molecular adaptations specifically induced by different muscle contraction types have only been partially elucidated. We previously demonstrated that eccentric contractions in human quadriceps elicited proteome modifications that suggest a muscle fiber typology adaptation. We address this question in a more systematic way by examining here the effects of different running modes on the mouse muscle proteome and the muscle fiber typology. Methods: Male adult mice (C57BL6) were randomly divided into downhill running (DHR, quadricipital eccentrically biased contractions), uphill running (UHR, quadricipital concentrically biased contractions) and untrained control (CONT) groups. Running groups performed five training sessions on an inclined treadmill for 75 to 135 min/day and the quadriceps muscles were dissected 96hours after the last session. Muscle protein extracts of DHR and UHR groups (n=4/group) were subjected to a 2D-DIGE analysis coupled with mass spectrometry. The assessment of fiber type, size and number was performed on the rectus femoris of the three groups (n=6/group) using myosin heavy chain (MHC) immunohistochemistry. Results: In the proteomic analysis, eight spots identified as the fast MHC isoforms exhibited a lower abundance in DHR compared to UHR (p<0.05, t-test). In contrast, ATP synthase subunit α and tubulin β were more expressed in DHR (p<0.05). A significant higher proportion of type I and IIa fibers was found for DHR compared to UHR or CONT groups (p<0.05, one-way ANOVA). Conclusions: Our data suggest that the eccentrically biased contractions in mice induced specific adaptations in protein expression and muscle fiber composition which may reflect a more oxidative muscle phenotype. The differences in stress placed on the muscle between both trainings may be responsible for some unique adaptations resulting from the eccentrically biased training. [less ▲]

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See detailA novel strategy towards cyclic aliphatic (co)polyesters
Gao, Ch; Li, Y; Chi, J et al

in eXPRESS Polymer Letters (2013), 7(8), 690-702

This feature article focuses on a novel strategy towards macrocyclic (co)polyesters that combines controlled ring-opening polymerization of lactones initiated by a cyclic tin(IV) dialkoxide and ... [more ▼]

This feature article focuses on a novel strategy towards macrocyclic (co)polyesters that combines controlled ring-opening polymerization of lactones initiated by a cyclic tin(IV) dialkoxide and intramolecular cyclization by photocross- linking of pendant unsaturations next to the propagating sites. No linear species is ever involved in the polymerization and permanent cyclization steps, which allows higher molecular weight macrocycles to be prepared with high efficiency and no need for further purification. Moreover, this synthetic route is very flexible to the point where macrocyclic polyesters with more complex although well-defined architectures, such as tadpole-shaped and sun-shaped copolyesters, can be tailored. Synthesis of well-defined eight-shaped polyesters and twin tadpole-shaped copolymers has also been explored by using a spirocyclic tin(IV) alkoxides as an initiator. When functional lactones were introduced, the ‘click’ copper-mediated cycloaddition [3+2] reaction was utilized to make the eight-shaped and twin tadpole-shaped copolyesters amphiphilic. [less ▲]

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See detailExpression of SV2 isoforms during rodent brain development
Crevecoeur, Julie; Foerch, P; Doupagne, Mélissa et al

in BMC Neuroscience (2013)

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See detailPostcolonial stakes of the Congolese political fields (DRC) in Belgium, 50 years after the Independance
Demart, Sarah ULg; Bodeux, Leila

in African Diaspora : a Journal of Transnational Africa in a Global World (2013)

This joint contribution interrogates the postcolonial relations that are at play in the Congolese political sphere in Belgium, the former colonial metropolis. Two lines of argument are developed. First ... [more ▼]

This joint contribution interrogates the postcolonial relations that are at play in the Congolese political sphere in Belgium, the former colonial metropolis. Two lines of argument are developed. First, the politicisation of the postcolonial relations, which pre-dates the Congolese immigration to Belgium, is viewed from a historical perspective. Second, the highly competitive political plu- ralism, as observed since the early 2000s, is examined. After having restored historically the con- stitution and the reconstruction of this political sphere, wherein new technologies deepen the transnational movements, the authors will examine the tensions that arise from the unifying dynamics of the politically engaged Diaspora, on the one hand, and its intrinsic logics of division and fragmentation, on the other. The postcolonial issues that are at stake are to be seen on differ- ent levels: transnational, local, within the Diaspora, and between the Congolese minority and the Belgian majority. Their interconnectedness further reveals the postcolonial character of this political sphere. [less ▲]

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See detailBulletin Bibliographique de la Société Rencesvals , 2012-2013
Henrard, Nadine ULg; Werner, Anne-Catherine ULg; Bauvir, Amandine ULg

in Bulletin Bibliographique de la Société Rencesvals (2013), 44(2012-2013), 249

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See detailEccentric rehabilitation for elbow hypermobility
Kaux, Jean-François ULg; Forthomme, Bénédicte ULg; FOIDART, Marguerite ULg et al

in Journal of Novel Physiotherapies (2013), 3(6), 1805

Introduction: Joint hypermobility involves an increased range of motion compared to normal amplitudes for the same age, sex and ethnic group. Patients with hypermobility suffer from joints problems and ... [more ▼]

Introduction: Joint hypermobility involves an increased range of motion compared to normal amplitudes for the same age, sex and ethnic group. Patients with hypermobility suffer from joints problems and chronic pain is the most frequently reported symptom. Eccentric muscle strengthening could be very important to protect hypermobile joints. Case report: An Ehler-Danlos syndrome patient presented pain in the right elbow and the right wrist after a season of tennis. Her physiotherapy (18 sessions, 3 times a week) consisted of wrist prono-supination and flexion-extension muscle group reinforcement and proprioceptive training. To protect the wrist against excessive load, the eccentric strengthening exercises of prono-supinator and flexor-extensor muscles of elbow and wrist were undertaken gradually, at increasing speeds [30°/s, 60°/s, and 90°/s] within a limited range of motion in flexion and extension, on an isokinetic device after an evaluation. She was also given an ortheosis restricting the joint range of motion of the wrist. The patient rapidly noted a decrease in pain and an increase in the stability of her right arm even when playing tennis. Isokinetic evaluation objectified an improvement in maximal torque of 20 to 25% in flexion-extension muscles of the right elbow. She was also given individualized home exercises. Conclusion: The goal of rehabilitation is to avoid hypermobility by using the muscles as a protective brake in the control of joint positioning. Muscles can be reinforced in eccentric mode with starting position at the maximum length of these muscles when unstreched. The exercises can be carried out safely on an isokinetic device, at slow speed and limited range of joint motion to avoid risk of luxation. Thus, in this case report, the eccentric exercises using an isokinetic device were effective to safely reinforce the muscles as a protective brake for joint hypermobility. [less ▲]

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See detailExperimental characterisation and modelling of homogeneous solid suspension in an industrial stirred tank
Calvo, Sébastien ULg; Delafosse, Angélique ULg; Collignon, Marie-Laure ULg et al

in Advances in Mechanical Engineering (2013), Volume 2013

In this work, we study the conditions needed to reach homogeneous distribution of aluminium salts particles in water inside a torispherical bottom shaped stirred tank of 70 L equipped with a Pfaudler RCI ... [more ▼]

In this work, we study the conditions needed to reach homogeneous distribution of aluminium salts particles in water inside a torispherical bottom shaped stirred tank of 70 L equipped with a Pfaudler RCI type impeller and three equispaced vertical baffles. The aim of the present study is to develop a CFD model describing the quality of particle distribution in industrial scale tanks. This model, validated with experimental data, is used afterwards to develop scale-up and scale-down correlations to predict the minimum impeller speed needed to reach homogeneous solid distribution Nhs.The commercial CFD software Fluent 14 is used to model the fluid flow and the solid particle distribution in the tank. Sliding Mesh approach is used to take the impeller motion into account. Assuming that the discrete solid phase has no influence on the continuous liquid phase behaviour, the fluid flow dynamics is simulated independently using the well-known k-ε turbulence model. The liquid-solid mixture behaviour is then described by implementing the Eulerian Mixture model. Computed liquid velocity fields are validated by comparison with PIV measurements. ComputedNhs were found to be in good agreement with experimental measurements. Results fromdifferent scales allowed correlating Nhs values to the volumetric power consumption. [less ▲]

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See detailIs mathematical history written by the victors ?
Bair, Jacques ULg; Henry, Valérie ULg; Blaszczyk, Piotr et al

in Notices of the American Mathematical Society (2013), 60(7), 886-904

We examine prevailing philosophical and historical views about the origin of infinitesimal mathematics in light of modern infinitesimal theories, and show the works of Fermat, Leibniz, Euler, Cauchy and ... [more ▼]

We examine prevailing philosophical and historical views about the origin of infinitesimal mathematics in light of modern infinitesimal theories, and show the works of Fermat, Leibniz, Euler, Cauchy and other giants of infinitesimal mathematics in a new light. Some topics from the history of infinitesimals illustrating our approach appear in alphabetical order. [less ▲]

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See detailExperimental and numerical investigations of the torsional flutter oscillations of a 4:1 rectangular cylinder
Andrianne, Thomas ULg; Dimitriadis, Grigorios ULg

in Journal of Fluids & Structures (2013), 41

The torsional flutter oscillations of a 4:1 rectangular cylinder around its pitching axis are investigated through wind tunnel experiments and numerical simulations. The rectangle’s responses to different ... [more ▼]

The torsional flutter oscillations of a 4:1 rectangular cylinder around its pitching axis are investigated through wind tunnel experiments and numerical simulations. The rectangle’s responses to different initial conditions and turbulence excitations at various wind tunnel airspeeds are recorded. Timeresolved Particle Image Velocimetry measurements are taken at two different airspeeds, when the rectangle undergoes Limit Cycle Oscillations. Aeroelastic simulations are carried out using the Discrete Vortex Method and the resulting responses are compared to the experimental measurements. The Common-base Proper Orthogonal Decomposition method is used to analyse and compare the measured and simulated unsteady flow fields around the rectangle. A discussion of the participation of each mode in the different states of the flow-field is presented, at two different amplitudes of oscillation. The Motion Induced Vortex (MIV) is identified as the fundamental cause of the torsional flutter phenomenon and its role over a complete cycle is studied. MIV-induced oscillations can be started either by a suitable initial disturbance or by a second, nearly linear self-excited instability that causes negative aerodynamic damping. The combination of these two instabilities results in a complete description of the torsional flutter of the rectangle. [less ▲]

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See detailAltered white matter architecture in BDNF Met carriers
Ziegler, Erik ULg; Foret, Ariane; Mascetti, Laura ULg et al

in PLoS ONE (2013)

Brain-derived neurotrophic factor (BDNF) modulates the pruning of synaptically-silent axonal arbors. The Met allele of the BDNF gene is associated with a reduction in the neurotrophin's activity-dependent ... [more ▼]

Brain-derived neurotrophic factor (BDNF) modulates the pruning of synaptically-silent axonal arbors. The Met allele of the BDNF gene is associated with a reduction in the neurotrophin's activity-dependent release. We used di ffusion-weighted imaging to construct structural brain networks for 36 healthy subjects with known BDNF genotypes. Through permutation testing we discovered clear di fferences in connection strength between subjects carrying the Met allele and those homozygotic for the Val allele. We trained a Gaussian process classi fier capable of identifying the subjects' allelic group with 86% accuracy and high predictive value. In Met carriers structural connectivity was greatly increased throughout the forebrain, particularly in connections corresponding to the anterior and superior corona radiata as well as corticothalamic and corticospinal projections from the sensorimotor, premotor and prefrontal portions of the internal capsule. Interhemispheric connectivity was also increased via the corpus callosum and anterior commissure, and extremely high connectivity values were found between inferior medial frontal polar regions via the anterior forceps. We propose that the decreased availability of BDNF leads to de cifits in axonal maintenance in carriers of the Met allele, and that this produces mesoscale changes in white matter architecture. [less ▲]

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See detailAn easy and low-cost method for preprocessing and matching small-scale amateur aerial photography for assessing agricultural land use in Burkina Faso
Wellens, Joost ULg; Midekor, Akoly; Traore, Farid ULg et al

in International Journal of Applied Earth Observation and Geoinformation (2013), 23

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See detailPrevalence and mechanisms of resistance to carbapenems in Enterobacteriaceae
Huang, Te-Din; Berhin, Catherine; Glupczynski, Youri et al

in Journal of Antimicrobial Chemotherapy (2013), 68(8), 1832-7

Objectives: To determine the point prevalence of carbapenem-non-susceptible Enterobacteriaceae (CNSE) and carbapenemase-producing Enterobacteriaceae (CPE) isolates among hospitalized patients in Belgium ... [more ▼]

Objectives: To determine the point prevalence of carbapenem-non-susceptible Enterobacteriaceae (CNSE) and carbapenemase-producing Enterobacteriaceae (CPE) isolates among hospitalized patients in Belgium. Methods: Twenty-four hospital-based laboratories prospectively collected 200 non-duplicated Enterobacteriaceae isolates from clinical specimens of hospitalized patients over a 2 month period. All isolates were screened locally for decreased susceptibility to carbapenem drugs using a disc diffusion method according to CLSI interpretative criteria. CNSE strains were referred centrally for confirmation of carbapenemase by phenotypic and molecular testing. Results: From February to April 2012, 158 of the 4564 screened Enterobacteriaceae isolates were categorized as non-susceptible to carbapenems, resulting in a point prevalence of CNSE of 3.5% (95% CI: 2.9%–4.2%; range per centre: 0.5%–8.5%). Of the 125 referred CNSE isolates, 11 Klebsiella pneumoniae isolates [OXA-48 (n=7), KPC type (n=3) and NDM type (n=1)], 1 OXA-48-positive Escherichia coli isolate and 1 KPC-positive Klebsiella oxytoca isolate were detected in eight hospitals. None of the 72 carbapenem-non-susceptible Enterobacter spp. isolates were confirmed as CPE. The minimal estimated point prevalence of CPE isolates was 0.28% (13/ 4564; 95% CI: 0.13%–0.44%) overall (range per centre: 0%–1.5%). Conclusions: Despite the overall low prevalence of CNSE found in this study, the detection of CPE isolates in one-third of the participating centres raises concerns and highly suggests the spread and establishment of CPE in Belgian hospitals. [less ▲]

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See detailBrentano and the parts of the mental: a mereological approach to phenomenal intentionality
Dewalque, Arnaud ULg

in Phenomenology and the Cognitive Sciences (2013), 12(3), 447-464

In this paper I explore one particular dimension of Brentano’s legacy, namely, his theory of mental analysis. This theory has received much less attention in recent literature than the intentionality ... [more ▼]

In this paper I explore one particular dimension of Brentano’s legacy, namely, his theory of mental analysis. This theory has received much less attention in recent literature than the intentionality thesis or the theory of inner perception. However, I argue that it provides us with substantive resources in order to conceptualize the unity of intentionality and phenomenality. My proposal is to think of the connection between intentionality and phenomenality as a certain combination of part/whole-relations rather than as a supervenience- or identity-relation. To begin, I discuss some reasons for being a (neo )Brentanian about the mind and briefly introduce the main characteristics of Brentano’s internalist description program. Then, I turn to the current ‘inseparatist’ way of dealing with intentionality and phenomenality, focusing on the demand for unity coming from advocates of phenomenal intentionality. I suggest that the unity of the mind may be put in a new light if we put aside metaphysical-epistemological questions, go back to Brentano’s description program, and endorse his thesis that the mental is something unified in which various parts must be distinguished. In the last section, I draw some lessons from this approach, holding that, for any representational content R, R is (in Brentano’s terms) an abstractive or ‘distinctional’ part of the relevant state, and that, for any qualitative aspect Q, Q is an abstractive or ‘distinctional’ part of the relevant representational content R. [less ▲]

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See detailTestosterone levels and fecundity in the hermaphroditic aquatic snail Lymnaea stagnalis exposed to testosterone and endocrine disruptors
Giusti, Arnaud ULg; Ducrot, Virginie; Joaquim-Justo, Célia ULg et al

in Environmental Toxicology & Chemistry (2013), 32(8), 1740-1745

Endocrine disruptors are known to alter endogenous free and/or esterified levels of androgenic and estrogenic steroid hormones in aquatic molluscs. However, there is still a controversy on the origin of ... [more ▼]

Endocrine disruptors are known to alter endogenous free and/or esterified levels of androgenic and estrogenic steroid hormones in aquatic molluscs. However, there is still a controversy on the origin of steroids in these animals. In this study, free and esterified testosterone concentrations were measured in the hermaphroditic aquatic gastropod Lymnaea stagnalis exposed to molecules known for their androgenic (testosterone and tributyltin), anti-androgenic (cyproterone-acetate) and estrogenic (chlordecone) properties by reference to their mode of action in vertebrates. In parallel, snail oviposition and fecundity were followed over the 21-day exposure period. Testosterone exposure resulted in increased esterified testosterone levels whereas free testosterone concentrations remained stable. In contrast, cyproterone-acetate increased significantly the free form of testosterone with no changes in the esterified form whereas chlordecone showed a tendency to reduce, though not significantly, esterified testosterone concentrations without changes in free testosterone levels. Finally, tributyltin did not alter testosterone homeostasis. The production of egg-clutches and eggs was significantly reduced only in the snails exposed to the highest concentrations of chlordecone (19.6 µg/L) and tributyltin (94.2 ng Sn/L). Overall, this study demonstrates that uptake of testosterone from the exposure medium occurs in L. stagnalis. Moreover, it shows that cyproterone-acetate and, to a lesser extent, chlordecone can alter endogenous testosterone levels in this freshwater snail. However, relationship between hormonal changes and snail reproduction has not been established. [less ▲]

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See detailProtective effect of a new biomaterial against the development of experimental osteoarthritis lesions in rabbit: a pilot study evaluating the intra-articular injection of alginate-chitosan beads dispersed in an hydrogel.
Oprenyeszk, Frédéric ULg; Chausson, Mickael; Maquet, Véronique et al

in Osteoarthritis and Cartilage (2013), 21(8), 1099-1107

Objective: This study aimed to evaluate the structural benefit of a new biomaterial composed of alginate-chitosan (AC) beads dispersed in an hydrogel (H) derived from chitosan on the development of ... [more ▼]

Objective: This study aimed to evaluate the structural benefit of a new biomaterial composed of alginate-chitosan (AC) beads dispersed in an hydrogel (H) derived from chitosan on the development of osteoarthritis (OA) in rabbit. Design: OA was induced by the surgical transection of the anterior cruciate ligament in rabbits. Animals received a single intra-articular injection (900 μl) of AC beads in H hydrogel, H hydrogel alone or saline one week after surgery. OA development was followed by X-rays. Blood samples were collected throughout the study to measure biological markers (PGE2 and CRP). Macroscopic observation and histological evaluation of articular cartilage and synovial membrane were performed 6 weeks after surgery. Results: AC beads in H hydrogel prevented from the development of OA based on the reduction of the Kellgren & Lawrence (K&L) score. It also significantly reduced the histological score of cartilage lesion severity. This effect was homogenous on every joint compartment. It was due to a significant effect on cartilage structure and cellularity scores. The injection of AC beads in H hydrogel also tended to reduce the synovial membrane inflammation. No significant variation of biological markers was noted. Conclusions: The present pilot study provides interesting and promising results for the use of AC beads in H hydrogel in animal. It indeed prevented the development of OA cartilage lesions without inflammatory signs. The potencies of this biomaterial to protect OA joint should be further documented. It could then represent a new alternative for viscosupplementation in human OA management. [less ▲]

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See detailOn the breakdown behavior of TCLUST clustering procedure
Ruwet, Christel ULg; Garcia-Escudero, Luis Angel; Gordaliza, Alfonso et al

in Test (2013), 22(3), 466-487

Clustering procedures allowing for general covariance structures of the obtained clusters need some constraints on the solutions. With this in mind, several proposals have been introduced in the ... [more ▼]

Clustering procedures allowing for general covariance structures of the obtained clusters need some constraints on the solutions. With this in mind, several proposals have been introduced in the literature. The TCLUST procedure works with a restriction on the "eigenvalues-ratio" of the clusters scatter matrices. In order to try to achieve robustness with respect to outliers, the procedure allows to trim off a proportion of the most outlying observations. The resistance to infinitesimal contamination of the TCLUST has already been studied. This paper aims to look at its resistance to a higher amount of contamination by means of the study of its breakdown behavior. The rather new concept of restricted breakdown point will demonstrate that the TCLUST procedure resists to a proportion of contamination equal to the trimming rate as soon as the data set is sufficiently "well clustered". [less ▲]

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See detailElévation faible d’hCG en dehors d’un contexte gravidique : à propos de deux cas et revue de la littérature
DE BACKER, Benjamin ULg; GOFFIN, Frédéric ULg; NISOLLE, Michelle ULg et al

in Annales de Biologie Clinique (2013), 71(4), 496-502

Unexpected finding or persistence of low human chorionic gonadotropin (hCG) levels is not a rare situation. It requires a clinico-biological approach in order to avoid misunderstandings that could lead to ... [more ▼]

Unexpected finding or persistence of low human chorionic gonadotropin (hCG) levels is not a rare situation. It requires a clinico-biological approach in order to avoid misunderstandings that could lead to inappropriate diagnostic or therapeutic attitudes. Beyond pregnancy, persistent low levels of hCG may be associated with various benign and malignant conditions, i.e. quiescent gestational trophoblastic disease (QTD), raised pituitary hCG or false positive elevation caused by circulating heterophile antibodies. We report the cases of two non-pregnant patients with low serum hCG. In the first case, hCG levels raised during several years following a spontaneous abortion. The likelihood of heterophilic antibodies interference was ruled out and extensive clinical investigation excluded the presence of a tumour. The diagnosis was QTD. In the second case, elevated hCG came to light as an incidental finding in a women with chronic renal failure and led the clinicians to question the laboratory. The cause was probably an increase in pituitary hCG consecutive to terminal renal failure. These cases illustrate the importance of understanding the biology of the hCG and the causes of its persistent low elevation, which are reviewed in this article. It is essential to demonstrate clinically the presence of a tumour in order to avoid unnecessary and ineffective chemotherapy and/or hysterectomy. [less ▲]

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See detailAutomated Processing of Zebrafish Imaging Data: A Survey
Mikut, Ralf; Dickmeis, Thomas; Driever, Wolfgang et al

in Zebrafish (2013), 10(3), 401-421

Due to the relative transparency of its embryos and larvae, the zebrafish is an ideal model organism for bioimaging approaches in vertebrates. Novel microscope technologies allow the imaging of ... [more ▼]

Due to the relative transparency of its embryos and larvae, the zebrafish is an ideal model organism for bioimaging approaches in vertebrates. Novel microscope technologies allow the imaging of developmental processes in unprecedented detail, and they enable the use of complex image-based read-outs for high-throughput/high-content screening. Such applications can easily generate Terabytes of image data, the handling and analysis of which becomes a major bottleneck in extracting the targeted information. Here, we describe the current state of the art in computational image analysis in the zebrafish system. We discuss the challenges encountered when handling high-content image data, especially with regard to data quality, annotation, and storage. We survey methods for preprocessing image data for further analysis, and describe selected examples of automated image analysis, including the tracking of cells during embryogenesis, heartbeat detection, identification of dead embryos, recognition of tissues and anatomical landmarks, and quantification of behavioral patterns of adult fish. We review recent examples for applications using such methods, such as the comprehensive analysis of cell lineages during early development, the generation of a three-dimensional brain atlas of zebrafish larvae, and high-throughput drug screens based on movement patterns. Finally, we identify future challenges for the zebrafish image analysis community, notably those concerning the compatibility of algorithms and data formats for the assembly of modular analysis pipelines. [less ▲]

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See detailTest modeling of the growth of self-fertilized embryos of Phaseolus vulgaris L. and Phaseolus coccineus L. genotypes
Nguema Ndoutoumou, Pamphile; Boussiengui Boussiengui, Gino; Ngakou, Albert et al

in African Journal of Plant Science (2013), 7(8), 310-316

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See detailContrast-enhanced nanofocus X-ray computed tomography allows virtual 3D histopathology and morphometric analysis of osteoarthritis in small animal models
Kerckhofs, Greet ULg; Sainz, J.; Maréchal, M. et al

in Cartilage (2013)

Objective: One of the early hallmarks of osteoarthritis (OA) is a progressive degeneration of the articular cartilage. Early diagnosis of OA-associated cartilage alterations would be beneficial for ... [more ▼]

Objective: One of the early hallmarks of osteoarthritis (OA) is a progressive degeneration of the articular cartilage. Early diagnosis of OA-associated cartilage alterations would be beneficial for disease prevention and control, and for the development of disease-modifying treatments. However, early diagnosis is still hampered by a lack of quantifiable readouts in preclinical models. Design: In this study, we have shown the potency of contrast-enhanced nanofocus x-ray computed tomography (CE-nanoCT) to be used for virtual 3-dimensional (3D) histopathology in established mouse models for OA, and we compared with standard histopathology. Results: We showed the equivalence of CE-nanoCT images to histopathology for the modified Mankin scoring of the cartilage structure and quality. Additionally, a limited set of 3D cartilage characteristics measured by CE-nanoCT image analysis in a user-independent and semiautomatic manner, that is, average and maximum of the noncalcified cartilage thickness distribution and loss in glycosaminoglycans, was shown to be predictive for the cartilage quality and structure as can be evaluated by histopathological scoring through the use of an empirical model. Conclusions: We have shown that CE-nanoCT is a tool that allows virtual histopathology and 3D morphological quantification of multitissue systems, such as the chondro-osseous junction. It provides faster and more quantitative data on cartilage structure and quality compared with standard histopathology while eliminating user bias. CE-nanoCT thus should allow capturing subtle differences in cartilage characteristics, carefully mapping OA progression and, ultimately, asses the beneficial changes when testing a candidate disease-modifying treatment. [less ▲]

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See detailTowards a bipartite graph modeling of the internet topology
Tarissan, Fabien; Quoitin, Bruno; Mérindol, Pascal et al

in Computer Networks (2013), 57(11), 2331-2347

Modeling the properties of the Internet topology aims at generating large scale artificial IP networks that mimic properties of real ones for simulation purposes. Current models typically consider the ... [more ▼]

Modeling the properties of the Internet topology aims at generating large scale artificial IP networks that mimic properties of real ones for simulation purposes. Current models typically consider the Internet as a simple graph where edges are point-to-point connections between routers. This approach does not take into account point-to-multipoint connections that exist at lower layers in the network, e.g. layer-2 clouds, such as Ethernet switches or MPLS networks. Instead, such physical point-to-multipoint connections are modeled as several logical IP level point-to-point connections. In this paper, we rely on recent developments in topology discovery based on IGMP probing that allows for revealing part of the network’s layer-2 structure. We take advantage of this additional knowledge for proposing an Internet model based on bipartite graphs considering both point-to-point and point-to-multipoint connections. Our model remains simple: it only takes as input the node degree sequence for both layer-2 and layer-3 nodes, randomly generates a bipartite graph respecting those distributions, and then derives the corresponding layer-3 topology. We show that, despite the simplicity of our model, realistic network properties, such as high local density, emerge naturally. This is in contrast with the now common belief that such properties can only appear with more intricate models or if explicitly injected in random models. Besides, we also provide evidences of how the analysis performed at the bipartite level might shed light on important properties of the real network structure. Finally, we propose and evaluate a bipartite graph generator based on our model that only takes two synthetic node degree distributions as input. [less ▲]

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See detailMALDI-FTICR MS Imaging as a Powerful Tool to Identify Paenibacillus Antibiotics Involved in the Inhibition of Plant Pathogens
Debois, Delphine ULg; Ongena, Marc ULg; Cawoy, Hélène ULg et al

in Journal of the American Society for Mass Spectrometry (2013), 24(8), 1202-1213

Nowadays, microorganisms are more and more often used as biocontrol agents for crop protection against diseases. Among them, bacteria of Bacillus and Paenibacillus genders are already used as commercial ... [more ▼]

Nowadays, microorganisms are more and more often used as biocontrol agents for crop protection against diseases. Among them, bacteria of Bacillus and Paenibacillus genders are already used as commercial biocontrol agents. Their mode of action is supposed to be related to their production of antibiotics, such as cyclic lipopeptides, which exhibit great antimicrobial activities. We chose to work with a Paenibacillus polymyxa strain (Pp56) very resistant to various microorganisms. The bacteria were grown simultaneously with Fusarium oxysporum and we applied matrix-assisted laser desorption/ionization-Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry to identify the antibiotics compounds present in the fungus growth inhibition area. We, therefore, identified fusaricidins A, B, and C and numerous members of the LI-F antibiotics family. MALDIFTICR mass spectrometry imaging was then used to follow the diffusion of lipopeptides involved in the inhibitory activity over time. We analyzed the molecular content of the inhibitory area at different Pp56 and Fusarium incubation durations and concluded that some lipopeptides such as fusaricidin B and a mixture of LI-F05b/06b/08a were mainly involved in the defense mechanism of Pp56. Our study confirms that MALDI imaging may be a powerful tool to quickly determine which molecular species is involved in an antagonism with another microorganism, avoiding time-consuming steps of extraction, purification, and activity tests, which are still commonly used in microbiology. [less ▲]

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See detailUse of 1,5-diaminonaphthalene to combine matrix-assisted laser desorption/ionization in-source decay fragmentation with hydrogen/deuterium exchange
Lemaire, Pascale; Debois, Delphine ULg; Smargiasso, Nicolas ULg et al

in Rapid Communications in Mass Spectrometry [=RCM] (2013), 27(16), 1837-1846

In-Source Decay (ISD) in Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry is a fast and easy top-down activation method. Our objective is to find a suitable matrix to locate the ... [more ▼]

In-Source Decay (ISD) in Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry is a fast and easy top-down activation method. Our objective is to find a suitable matrix to locate the deuterons following in-solution hydrogen/deuterium exchange (HDX). This matrix must circumvent the commonly encountered undesired back-exchange reactions, in order to preserve the regioselective deuteration pattern. The 1,5-diaminonaphthalene (1,5-DAN) matrix is known to be suitable for MALDI-ISD fragmentation. MALDI Mass Spectrometry Imaging (MSI) was employed to compare 1,5-DAN and other commonly used MALDI matrices with respect to the extent of back-exchange and the uniformity of the H/D exchange profiles within the MALDI spots. We tested the back-exchange on the highly sensitive amyloid-beta peptide (1-40), and proved the regioselectivity on ubiquitin and b-endorphin. MALDI-MSI results show that 1,5-DAN leads to the least back-exchange over all the spot. MALDI-ISD fragmentation combined with H/D exchange using 1,5-DAN matrix was validated by localizing deuterons in native ubiquitin. Results agree with previous data obtained by Nuclear Magnetic Resonance (NMR) and Electron Transfer Dissociation (ETD). Moreover, 1,5-DAN matrix was used to study the H/D exchange profile of the methanol-induced helical structure of b-endorphin, and the relative protection can be explained by the polarity of residues involved in hydrogen bond formation. We found that controlling crystallization is the most important parameter when combining H/D exchange with MALDI. The 1,5-DAN matrix is characterized by a fast crystallization kinetics, and therefore gives robust and reliable H/D exchange profiles using MALDI-ISD. [less ▲]

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See detailMesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: Lessons Learned from First Clinical Trials.
Franquesa, Marcella; Hoogduijn, Martin J.; Reinders, Marlies E. et al

in Transplantation (2013), 96(3), 234-238

The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of ... [more ▼]

The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies. [less ▲]

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See detailCongolese migration to Belgium and postcolonial perspectives
Demart, Sarah ULg

in African Diaspora : a Journal of Transnational Africa in a Global World (2013), 6

Long absent from the scholarly literature, Congolese migration to Belgium now occupies a greater place in academic research. Nevertheless the various disciplinary approaches undertaken and the many topics ... [more ▼]

Long absent from the scholarly literature, Congolese migration to Belgium now occupies a greater place in academic research. Nevertheless the various disciplinary approaches undertaken and the many topics of interest explored have not exhausted the complexity of this diaspora, too often the object of prejudice in popular opinion and public policies. The position of “the Congolese issue” in the academic world is thus rarely problematized due to confusion over how to categorize the Congo and the Congolese – either as ‘Africa,’ ‘Central Africa,’ ‘Sub-Sahara,’ etc. This reflects a ‘geography of the Other’ that significantly confounds current social processes at work in Belgium and the particularity of this (post)migratory situation. Grounded in empirical research, this issue in moving beyond merely highlighting a relatively marginalized group in Belgian Migration Studies, is focusing on the postcolonial stakes of the Congolese presence in Belgium. The authors take different viewpoints to explore the place of the Congolese in the former metropole and the forms of marginalization they face. The everyday life, the state regulations and the dynamics of identity are then various lens to bring to light the racial logics at work in the Belgian multiculturalism. [less ▲]

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See detailRISK OF RED BLOOD CELL ALLOIMMUNISATION IN RWANDA : ASSESSMENT OF PRETRANSFUSION CROSSMATCH TECHNIQUES USED IN DISTRICT HOSPITALS
NDAHIMANA, E; GOTHOT, André ULg; GERARD, Christiane ULg et al

in East African Medical Journal (2013), 90(8), 277-282

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See detailDirect observation of the depairing current density in single-crystalline Ba0.5K0.5Fe2As2 microbridge with nanoscale thickness
Li, Jun; Yuan, Jie; Yuan, Ya-Hua et al

in Applied Physics Letters (2013), 103

We investigated the critical current density (Jc) of Ba0.5K0.5Fe2As2 single-crystalline microbridges with thicknesses ranging from 276 to 18 nm. The Jc of the microbridge with thickness down to 91 nm is ... [more ▼]

We investigated the critical current density (Jc) of Ba0.5K0.5Fe2As2 single-crystalline microbridges with thicknesses ranging from 276 to 18 nm. The Jc of the microbridge with thickness down to 91 nm is 10.8 MA/cm2 at 35 K, and reaches 944.4 MA/cm2 by extrapolating Jc(T) to T = 0 K using a two-gap s-wave Ginzburg-Landau model, well in accordance with the depairing current limit. The temperature, magnetic field, and angular-dependence of Jc(T,H,q) indicated weaker field dependence and weakly anisotropic factor of 1.15 (1 T) and 1.26 (5 T), which also yielded the validity of the anisotropic Ginzburg-Landau scaling. [less ▲]

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See detailAspects du symbolique dans la sociologie de Pierre Bourdieu. Formation et transformations d'un concept générateur
Durand, Pascal ULg; Dubois, Jacques ULg; Winkin, Yves ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2013)

L’auteur du « Sens pratique » a toujours veillé à marquer sa défiance à l’égard des exposés théoriques trop systématiques, estimant qu’ils induisaient un théoricisme assez vain. Plusieurs notions clés de ... [more ▼]

L’auteur du « Sens pratique » a toujours veillé à marquer sa défiance à l’égard des exposés théoriques trop systématiques, estimant qu’ils induisaient un théoricisme assez vain. Plusieurs notions clés de son appareil théorique, telles que celles d’« habitus » ou de « champ », n’en ont pas moins fait l’objet de mises au point méthodiques et ont été reprises à ce titre par de nombreux commentateurs. Rien de semblable pour le « symbolique ». Une explication partielle en réside dans le fait que la notion n’accède que rarement chez Bourdieu à la forme substantive. Ce flou sémantique a été propice à bien des interprétations réductrices, dont celle qui tend à rabattre le « symbolique » tantôt simplement sur le culturel, tantôt plus largement sur l’immatériel, est l’une des plus reçues, que ce soit du côté des études littéraires, où il en est fait grand usage en ce sens, ou du côté d’autres sociologues peu disposés à se mesurer véritablement à la pensée qu’ils discutent. C'est peut-être bien, pourtant, dans cette catégorie du « symbolique » que se condense la pensée sociologique de Bourdieu dans ce qu’elle a de plus irréductible. On tente ici de le montrer en profilant à travers l’œuvre – depuis les premiers travaux anthropologiques jusqu’au grand cours du Collège de France sur l’État – quelques-uns des principaux emplois, champs et lieux d’intervention dans le cadre desquels le « symbolique » aura joué de son pouvoir de redéfinition critique d’autres concepts et de conversion du regard sur des objets, des pratiques, des concepts ordinairement réifiés ou relayés sans recul par la sociologie de sens commun. [less ▲]

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See detailCompte rendu de D. Manetti, Anonymus Londiniensis. De medicina, Berlin–New York, W. de Gruyter, 2011 (= Bibliotheca Teubneriana 2003)
Ricciardetto, Antonio ULg

in Aestimatio: Critical Reviews in the History of Science (2013), 10

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See detailIn-Source Decay during Matrix-Assisted Laser Desorption/Ionization Combined with the Collisional Process in an FTICR Mass Spectrometer
Asakawa, Daiki; Calligaris, David; Zimmerman, Tyler et al

in Analytical Chemistry (2013), 85

The type of ions detected after in-source decay (ISD) in a MALDI source differs according to the ion source pressure and on the mass analyzer used. We present the mechanism leading to the final ISD ions ... [more ▼]

The type of ions detected after in-source decay (ISD) in a MALDI source differs according to the ion source pressure and on the mass analyzer used. We present the mechanism leading to the final ISD ions for a Fourier transform-ion cyclotron resonance mass spectrometer (FTICR MS). The MALDI ion source was operated at intermediate pressure to cool the resulting ions and increase their lifetime during the long residence times in the FTICR ion optics. This condition produces not only c′, z′, and w fragments, but also a, y′, and d fragments. In particular, d ions help to identify isobaric amino acid residues present near the Nterminal amino acid. Desorbed ions collide with background gas during desorption, leading to proton mobilization from Arg residues to a less favored protonation site. As a result, in the case of ISD with MALDI FTICR, the influence of the Arg residue in ISD fragmentation is less straightforward than for TOF MS and the sequence coverage is thus improved. MALDI-ISD combined with FTICR MS appears to be a useful method for sequencing of peptides and proteins including discrimination of isobaric amino acid residues and site determination of phosphorylation. Additionally we also used new software for in silico elimination of MALDI matrix peaks from MALDI-ISD FTICR mass spectra. The combination of high resolving power of an FTICR analyzer and matrix subtraction software helps to interpret the low m/z region of MALDI-ISD spectra. Finally, several of these developed methods are applied in unison toward a MALDI ISD FTICR imaging experiment on mouse brain to achieve better results. [less ▲]

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See detailAcetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model
Lodewick, Julie; Sampaio, Carla; Boxus, Mathieu et al

in Retrovirology (2013), 2013(10), 75

Background Transformation by the Tax oncoprotein of the human T cell leukemia virus type 1 (HTLV-1) is governed by actions on cellular regulatory signals, including modulation of specific cellular gene ... [more ▼]

Background Transformation by the Tax oncoprotein of the human T cell leukemia virus type 1 (HTLV-1) is governed by actions on cellular regulatory signals, including modulation of specific cellular gene expression via activation of signaling pathways, acceleration of cell cycle progression via stimulation of cyclin-dependent kinase activity leading to retinoblastoma protein (pRb) hyperphosphorylation and perturbation of survival signals. These actions control early steps in T cell transformation and development of Adult T cell leukemia (ATL), an aggressive malignancy of HTLV-1 infected T lymphocytes. Post-translational modifications of Tax by phosphorylation, ubiquitination, sumoylation and acetylation have been implicated in Tax-mediated activation of the NF-B pathway, a key function associated with Tax transforming potential. Results In this study, we demonstrate that acetylation at lysine K346 in the carboxy-terminal domain of Tax is modulated in the Tax nuclear bodies by the acetyltransferase p300 and the deacetylases HDAC5/7 and controls phosphorylation of the tumor suppressor pRb by Tax-cyclin D3-CDK4-p21CIP complexes. This property correlates with the inability of the acetylation deficient K346R mutant, but not the acetylation mimetic K346Q mutant, to promote anchorage-independent growth of Rat-1 fibroblasts. By contrast, acetylation at lysine K346 had no effects on the ability of Tax carboxy-terminal PDZ-binding domain to interact with the tumor suppressor hDLG. Conclusions The identification of the acetyltransferase p300 and the deacetylase HDAC7 as enzymes modulating Tax acetylation points to new therapeutic targets for the treatment of HTLV-1 infected patients at risk of developing ATL. [less ▲]

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See detailAbove-ground biomass and structure of 260 african tropical forests
Lewis, Simon L.; Sonké, Bonaventure; Sunderland, Terry et al

in Philosophical Transactions of the Royal Society B (2013), 368

We report above-ground biomass (AGB), basal area, stemdensity and wood mass density estimates from 260 sample plots (mean size: 1.2 ha) in intact closed-canopy tropical forests across 12 African countries ... [more ▼]

We report above-ground biomass (AGB), basal area, stemdensity and wood mass density estimates from 260 sample plots (mean size: 1.2 ha) in intact closed-canopy tropical forests across 12 African countries. Mean AGB is 395.7 Mg dry mass ha21 (95% CI: 14.3), substantially higher than Amazonian values, with the Congo Basin and contiguous forest region attaining AGB values (429 Mg ha21) similar to those of Bornean forests, and significantly greater than East or West African forests. AGB therefore appears generally higher in palaeo- comparedwithneotropical forests.However, mean stem density is low(426+11 stems ha21 greater than or equal to 100 mm diameter) compared with both Amazonian and Bornean forests (cf. approx. 600) and is the signature structural feature of African tropical forests. While spatial autocorrelation complicates analyses, AGB shows a positive relationship with rainfall in the driest nine months of the year, and an opposite association with the wettest three months of the year; a negative relationship with temperature; positive relationship with clay-rich soils; and negative relationshipswith C :Nratio (suggesting a positive soil phosphorus–AGB relationship), and soil fertility computed as the sum of base cations. The results indicate that AGB is mediated by both climate and soils, and suggest that the AGB of African closed-canopy tropical forests may be particularly sensitive to future precipitation and temperature changes. [less ▲]

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See detailClimatic and cultural changes in the west Congo Basin forests over the past 5000 years
Oslisly, Richard; White, Lee; Bentaleb, Ilham et al

in Philosophical Transactions : Biological Sciences (2013), 368(1625), 1-11

Central Africa includes the world's second largest rainforest block. The ecology of the region remains poorly understood, as does its vegetation and archaeological history. However, over the past 20 years ... [more ▼]

Central Africa includes the world's second largest rainforest block. The ecology of the region remains poorly understood, as does its vegetation and archaeological history. However, over the past 20 years, multidisciplinary scientific programmes have enhanced knowledge of old human presence and palaeoenvironments in the forestry block of Central Africa. This first regional synthesis documents significant cultural changes over the past five millennia and describes how they are linked to climate. It is now well documented that climatic conditions in the African tropics underwent significant changes throughout this period and here we demonstrate that corresponding shifts in human demography have had a strong influence on the forests. The most influential event was the decline of the strong African monsoon in the Late Holocene, resulting in serious disturbance of the forest block around 3500 BP. During the same period, populations from the north settled in the forest zone; they mastered new technologies such as pottery and fabrication of polished stone tools, and seem to have practised agriculture. The opening up of forests from 2500 BP favoured the arrival of metallurgist populations that impacted the forest. During this long period (2500–1400 BP), a remarkable increase of archaeological sites is an indication of a demographic explosion of metallurgist populations. Paradoxically, we have found evidence of pearl millet (Pennisetum glaucum) cultivation in the forest around 2200 BP, implying a more arid context. While Early Iron Age sites (prior to 1400 BP) and recent pre-colonial sites (two to eight centuries BP) are abundant, the period between 1600 and 1000 BP is characterized by a sharp decrease in human settlements, with a population crash between 1300 and 1000 BP over a large part of Central Africa. It is only in the eleventh century that new populations of metallurgists settled into the forest block. In this paper, we analyse the spatial and temporal distribution of 328 archaeological sites that have been reliably radiocarbon dated. The results allow us to piece together changes in the relationships between human populations and the environments in which they lived. On this basis, we discuss interactions between humans, climate and vegetation during the past five millennia and the implications of the absence of people from the landscape over three centuries. We go on to discuss modern vegetation patterns and African forest conservation in the light of these events. [less ▲]

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See detailLa couleur dans l'environnement urbain - Validation d'un protocole de caractérisation chromatique
Nguyen, Ngoc Luan ULg; Teller, Jacques ULg

in Ambiances : Revue Internationale sur l'Environnement Sensible, l'Architecture et l'Espace Urbain (2013)

The aim of this paper is to present a user-oriented protocol for the characterization of colour attributes in an urban fragment. The challenge is to provide quantitative answers to these questions: how is ... [more ▼]

The aim of this paper is to present a user-oriented protocol for the characterization of colour attributes in an urban fragment. The challenge is to provide quantitative answers to these questions: how is colour organized? How does it develop a structure in the city? Our research investigates stable colour typologies. The obvious lack of effective tools for the chromatic assessment in the field of urban design was the main motivation of this research. The protocol is illustrated within the study of the “rue des Anglais” in Liège (Belgium) and the stability of the method is conducted through a series of validations. [less ▲]

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See detailAn interferometric study of the Fomalhaut inner debris disk. III. Detailed models of the exozodiacal disk and its origin
Lebreton, J; van Lieshout, R; Augereau, J-C et al

in Astronomy and Astrophysics (2013), 555

Context. Debris disks are thought to be extrasolar analogues to the Solar System planetesimal belts. The star Fomalhaut harbors a cold debris belt at 140AU comparable to the Edgeworth-Kuiper belt, as well ... [more ▼]

Context. Debris disks are thought to be extrasolar analogues to the Solar System planetesimal belts. The star Fomalhaut harbors a cold debris belt at 140AU comparable to the Edgeworth-Kuiper belt, as well as evidence for a warm dust component, unresolved by single-dish telescopes, that is suspected to be a bright analogue to the Solar System's zodiacal dust. Aims. Interferometric observations obtained with the VLTI/VINCI instrument and the Keck Interferometer Nuller have identi fied near- and mid-infrared excesses attributed respectively to hot and warm exozodiacal dust residing in the inner few AU of the Fomalhaut environment. We aim to characterize the properties of this double inner dust belt and to unveil its origin. Methods.We perform parametric modelling of the exozodiacal disk ("exozodi") using the GRaTer radiative transfer code in order to reproduce the interferometric data, complemented by mid- to far-infrared photometric measurements from Spitzer and Herschel. A detailed treatment of sublimation temperatures is introduced to explore the hot population at the size-dependent sublimation rim. We then use an analytical approach to test successively several source mechanisms for the dust and suspected parent bodies. Results. A good fi t to the multi-wavelength data is found by two distinct dust populations: (1) a population of very small (0.01 to 0.5 µ m) and therefore unbound, hot dust grains con ned in a narrow region ( ~0.1 - 0.3 AU) at the sublimation rim of carbonaceous material; (2) a population of bound grains at 2AU that is protected from sublimation and has a larger mass despite its fainter flux level. We propose that the hot dust is produced by the release of small carbon grains following the disruption of dust aggregates that originate from the warm component. A mechanism such as gas braking is required to further con ne the small grains for long enough. In situ dust production could hardly be ensured for the age of the star and we conclude that the observed amount of dust is triggered by intense dynamical activity. Conclusions. Fomalhaut may be representative of exozodis that are currently being surveyed at near and mid-infrared wavelengths worldwide. We propose a framework for reconciling the "hot exozodi phenomenon" with theoretical constraints: the hot component of Fomalhaut is likely the "tip of the iceberg" as it could derive from the more massive, but fainter, warm dust component residing near the ice line. This inner disk exhibits interesting morphology and can be considered a prime target for future exoplanet research. [less ▲]

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See detailCharacterization and optimization of GMO-based gels with long term release for intraarticular administration
Réeff, J.; Gaignaux, A.; Goole, J. et al

in International Journal of Pharmaceutics (2013), 451(1-2), 95-103

Osteoarthritis is characterized by slow degenerative processes in the articular cartilage within synovial joints. It could be interesting to develop a sustained-release formulation that could be effective ... [more ▼]

Osteoarthritis is characterized by slow degenerative processes in the articular cartilage within synovial joints. It could be interesting to develop a sustained-release formulation that could be effective on both pain/inflammation and restoration of mechanical integrity of the joint. Recently, an injectable system based on glycerol monooleate (GMO), containing clonidine as a model hydrophilic analgesic/anti-inflammatory drug and hyaluronic acid as a viscoelastic scaffold, showed promising potential as a biodegradable and biocompatible preparation to sustain the drug activity. However, drug release from the system is relatively fast (complete within 1 week) and the underlying drug release mechanisms not fully understood. The aims of this study were: (i) to significantly improve this type of local controlled drug delivery system by further sustaining clonidine release, and (ii) to elucidate the underlying mass transport mechanisms. The addition of FDA-approved inactive ingredients such as sodium oleate or purified soybean oil was found to be highly effective. The release rate could be substantially reduced (e.g., 50% release after 10 days), due to the increased hydrophobicity of the systems, resulting in slower and reduced water uptake and reduced drug mobility. Interestingly, Fick's second law of diffusion could be used to quantitatively describe drug release. [less ▲]

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See detailHow dynamical clustering triggers Maxwell's demon in microgravity
Opsomer, Eric ULg; Noirhomme, Martial ULg; Vandewalle, Nicolas ULg et al

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2013), 88

In microgravity, the gathering of granular material can be achieved by a dynamical clustering whose existence depends on the geometry of the cell that contains the particles and the energy that is ... [more ▼]

In microgravity, the gathering of granular material can be achieved by a dynamical clustering whose existence depends on the geometry of the cell that contains the particles and the energy that is injected into the system. By compartmentalizing the cell in several subcells of smaller volume, local clustering is triggered and the so formed dense regions act as stable traps. In this paper, molecular dynamics simulations were performed in order to reproduce the phenomenon and to analyze the formation and the stability of such traps. Depending on the total number N of particles present in the whole system, several clustering modes are encountered and a corresponding bifurcation diagram is presented. Moreover, an iterative model based on the measured particle flux F as well as a theoretical model giving the asymptotical steady states are used to validate our results. The obtained results are promising and can provide ways to manipulate grains in microgravity. [less ▲]

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See detailRebound of a confined granular material: combination of a bouncing ball and a granular damper.
Pacheco Vazquez, Felipe ULg; Dorbolo, Stéphane ULg

in Scientific Reports (2013), 3(2158), 10103802158

A ball dropped over a solid surface bounces several times before a complete stop. The bouncing can be reduced by introducing a liquid into the ball; however, the first rebound remains largely unaffected ... [more ▼]

A ball dropped over a solid surface bounces several times before a complete stop. The bouncing can be reduced by introducing a liquid into the ball; however, the first rebound remains largely unaffected by the fluid. Granular materials can also work as dampers. We investigated the rebound of a container partially filled with a given mass of grains mi. During the collision, the kinetic energy of the container is partially transferred to the grains, the rebound is damped, and the fast energy dissipation through inter-particle collisions and friction decreases the bouncing time dramatically. For grain-filled cylinders, a completely inelastic collision (zero rebound) is obtained when mi≥1.5εomc, where εo and mc are the coefficient of restitution and mass of the empty container. For grain-filled spheres, the first rebound is almost undamped, but the second collision is completely inelastic if mi>>mc. These findings are potentially useful to design new granular damping systems. [less ▲]

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See detailSubproblem Approach for Modeling Multiply Connected Thin Regions with an h-Conformal Magnetodynamic Finite Element Formulation
Dang, Quoc Vuong ULg; Dular, Patrick ULg; Vazquez Sabariego, Ruth ULg et al

in European Physical Journal : Applied physics (2013), in press

A subproblem h-conformal eddy current nite element method is proposed for correcting the inaccuracies inherent to thin shell models. Such models replace volume thin regions by surfaces but neglect border ... [more ▼]

A subproblem h-conformal eddy current nite element method is proposed for correcting the inaccuracies inherent to thin shell models. Such models replace volume thin regions by surfaces but neglect border e ects in the vicinity of their edges and corners. The developed surface-to-volume correction problem is de ned as a step of the multiple subproblems that can split a complete problem, consisting of inductors and magnetic or conducting regions, some of these being thin regions. The general case of multiply connected thin regions is considered [less ▲]

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See detailA near-infrared interferometric survey of debris disc stars. III. First statistics based on 42 stars observed with CHARA/FLUOR
Absil, Olivier ULg; Defrère, Denis; Coudé du Foresto, Vincent et al

in Astronomy and Astrophysics (2013), 555

Context. Dust is expected to be ubiquitous in extrasolar planetary systems due to the dynamical activity of minor bodies. Inner dust populations are, however, still poorly known due to the high contrast ... [more ▼]

Context. Dust is expected to be ubiquitous in extrasolar planetary systems due to the dynamical activity of minor bodies. Inner dust populations are, however, still poorly known due to the high contrast and small angular separation with respect to their host star. Yet, a proper characterisation of exozodiacal dust is mandatory for the design of future Earth-like planet imaging missions. Aims. We aim to determine the level of near-infrared exozodiacal dust emission around a sample of 42 nearby main sequence stars with spectral types ranging from A to K, and to investigate its correlation with various stellar parameters and with the presence of cold dust belts. Methods. We use high-precision K-band visibilities obtained with the FLUOR interferometer on the shortest baseline of the CHARA array. The calibrated visibilities are compared with the expected visibility of the stellar photosphere to assess the presence of an additional, fully resolved circumstellar emission source. Results. Near-infrared circumstellar emission amounting to about 1% of the stellar flux is detected around 13 of our 42 target stars. Follow-up observations showed that one of them (eps Cep) is associated with a stellar companion, while another one was detected around what turned out to be a giant star (kap CrB). The remaining 11 excesses found around single main sequence stars are most probably due to the presence of hot circumstellar dust, yielding an overall occurrence rate of 28+8-6% for our (biased) sample. We show that the occurrence rate of bright exozodiacal discs correlates with spectral type, K-band excesses being more frequent around A-type stars. It also correlates with the presence of detectable far-infrared excess emission in the case of solar-type stars. Conclusions. This study provides new insights regarding the phenomenon of bright exozodiacal disc, showing that hot dust populations are probably linked to outer dust reservoirs in the case of solar-type stars. In the case of A-type stars, no clear conclusion can be made regarding the origin of the detected near-infrared excesses. [less ▲]

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See detailCholecaciferol in haemodialysis patients: a randomized, double-blind, proof-of-concept and safety study
DELANAYE, Pierre ULg; WEEKERS, Laurent ULg; WARLING, Xavier et al

in Nephrology Dialysis Transplantation (2013), 28(7), 1779-1786

Background. The role of cholecalciferol supplementation in end-stage renal disease (ESRD) patients has been questioned. The objective of this randomized double-blinded study is to assess whether ... [more ▼]

Background. The role of cholecalciferol supplementation in end-stage renal disease (ESRD) patients has been questioned. The objective of this randomized double-blinded study is to assess whether cholecalciferol therapy can increase serum 25-hydroxyvitamin D [25(OH)D] levels in haemodialysed patients and the safety implications of this therapy on certain biological parameters and vascular calcifications score. Methods. Forty-three haemodialysis patients were randomized to receive placebo or cholecalciferol (25 000 IU) therapy every 2 weeks. The biological parameters, serum calcium, phosphorus, 25(OH)D and parathormone (PTH) levels, were monitored monthly for 12 consecutive months. Vascular calcifications were assessed by lateral X-ray radiography. Results. At baseline, the mean serum 25(OH)D levels were low and similar in both groups. Thirty patients (16 treated and 14 placebo) completed the study: 11 patients died (5 placebo and 6 treated), 1 patient dropped out and 1 patient was transplanted (both from the placebo group). After 1 year, the percentage of 25(OH)D deficient patients was significantly lower in the treated group. None of the patients developed hypercalcaemia. The PTH levels tended to increase over the study period under placebo and to decrease in the cholecalciferol group. The median changes in PTH levels from baseline to 1 year were statistically different between the two groups [+80 (−58 to 153) and −115 (−192 to 81) under placebo and cholecalciferol treatment, respectively, P = 0.02].The calcification scores increased equivalently in both groups (+2.3 per year). Conclusions. Cholecalciferol is effective and safe, and does not negatively affect calcium, phosphorus, PTH levels and vascular calcifications. Additional studies are needed to compare the impacts of nutritional and active vitamin D agents on vascular calcification and mortality. [less ▲]

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See detailWeb-based interventions to promote physical activity by older adults: promising perspectives for a public health challenge
Mouton, Alexandre ULg; Cloes, Marc ULg

in Archives of Public Health (2013), 71

Regular physical activity is associated with a wide range of health benefits. As population age, promotion of physical activity should specifically target older adults, an expanding group involving ... [more ▼]

Regular physical activity is associated with a wide range of health benefits. As population age, promotion of physical activity should specifically target older adults, an expanding group involving potential higher health care costs in the near future. Innovative interventions focusing on physical activity behaviors of senior adults exposed promising results, most recently through the use of the Internet. If seniors and Internet are generally considered as two opposite concepts, arguments in favour of bringing them together in a public health perspective have been identified by the recent literature. Older adults are the fastest growing group of Internet users and are more prone than younger to use it for health-related subjects. Web-based interventions are effective in many health promotion sectors, including physical activity. This is particularly true when interventions target the environmental determinants of each senior citizen and are specifically designed for this population. Those early research findings must clearly be extended, particularly regarding to the long term effects of Webbased physical activity interventions. Solutions that will reduce the high dropout rate recorded in the existing literature must also be considered as a priority in order to ensure the development of this forward-looking field of research. [less ▲]

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See detailEffects of Neurally Adjusted Ventilatory Assist (NAVA) levels in non-invasive ventilated patients: titrating NAVA levels with electric diaphragmatic activity and tidal volume matching
Chiew, YS; Chase, JG; LAMBERMONT, Bernard ULg et al

in BioMedical Engineering OnLine (2013)

BACKGROUND: Neurally adjusted ventilatory assist (NAVA) delivers pressure in proportion to diaphragm electrical activity (Eadi). However, each patient responds differently to NAVA levels. This study aims ... [more ▼]

BACKGROUND: Neurally adjusted ventilatory assist (NAVA) delivers pressure in proportion to diaphragm electrical activity (Eadi). However, each patient responds differently to NAVA levels. This study aims to examine the matching between tidal volume (Vt) and patients' inspiratory demand (Eadi), and to investigate patient-specific response to various NAVA levels in non-invasively ventilated patients. METHODS: 12 patients were ventilated non-invasively with NAVA using three different NAVA levels. NAVA100 was set according to the manufacturer's recommendation to have similar peak airway pressure as during pressure support. NAVA level was then adjusted ±50% (NAVA50, NAVA150). Airway pressure, flow and Eadi were recorded for 15 minutes at each NAVA level. The matching of Vt and integral of Eadi (ʃEadi) were assessed at the different NAVA levels. A metric, Range90, was defined as the 5-95% range of Vt/ʃEadi ratio to assess matching for each NAVA level. Smaller Range90 values indicated better matching of supply to demand. RESULTS: Patients ventilated at NAVA50 had the lowest Range90 with median 25.6 uVs/ml [Interquartile range (IQR): 15.4-70.4], suggesting that, globally, NAVA50 provided better matching between ʃEadi and Vt than NAVA100 and NAVA150. However, on a per-patient basis, 4 patients had the lowest Range90 values in NAVA100, 1 patient at NAVA150 and 7 patients at NAVA50. Robust coefficient of variation for ʃEadi and Vt were not different between NAVA levels. CONCLUSIONS: The patient-specific matching between ʃEadi and Vt was variable, indicating that to obtain the best possible matching, NAVA level setting should be patient specific. The Range90 concept presented to evaluate Vt/ʃEadi is a physiologic metric that could help in individual titration of NAVA level. [less ▲]

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See detailHerschel's "Cold Debris Disks": Background Galaxies or Quiescent Rims of Planetary Systems?
Krivov, A. V.; Eiroa, C.; Löhne, T. et al

in Astrophysical Journal (2013), 772

(abridged) Infrared excesses associated with debris disk host stars detected so far peak at wavelengths around ~100{\mu}m or shorter. However, six out of 31 excess sources in the Herschel OTKP DUNES have ... [more ▼]

(abridged) Infrared excesses associated with debris disk host stars detected so far peak at wavelengths around ~100{\mu}m or shorter. However, six out of 31 excess sources in the Herschel OTKP DUNES have been seen to show significant - and in some cases extended - excess emission at 160{\mu}m, which is larger than the 100{\mu}m excess. This excess emission has been suggested to stem from debris disks colder than those known previously. Using several methods, we re-consider whether some or even all of the candidates may be associated with unrelated galactic or extragalactic emission and conclude that it is highly unlikely that none of the candidates represents a true circumstellar disk. For true disks, both the dust temperatures inferred from the SEDs and the disk radii estimated from the images suggest that the dust is nearly as cold as a blackbody. This requires the grains to be larger than ~100{\mu}m, regardless of their material composition. To explain the dearth of small grains, we explore several conceivable scenarios: transport-dominated disks, disks of low dynamical excitation, and disks of unstirred primordial macroscopic grains. Our qualitative analysis and collisional simulations rule out the first two of these scenarios, but show the feasibility of the third one. We show that such disks can survive for gigayears, largely preserving the primordial size distribution. They should be composed of macroscopic solids larger than millimeters, but smaller than kilometers in size. Thus planetesimal formation, at least in the outer regions of the systems, has stopped before "cometary" or "asteroidal" sizes were reached. [less ▲]

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See detailForbidden oxygen lines in comets at various heliocentric distances
Decock, Alice ULg; Jehin, Emmanuel ULg; Hutsemekers, Damien ULg et al

in Astronomy and Astrophysics (2013), 555

We present a study of the three forbidden oxygen lines [OI] located in the optical region - i.e., 5577.339 Å (the green line), 6300.304 Å and 6363.776 Å (the two red lines) - in order to better understand ... [more ▼]

We present a study of the three forbidden oxygen lines [OI] located in the optical region - i.e., 5577.339 Å (the green line), 6300.304 Å and 6363.776 Å (the two red lines) - in order to better understand the production of these atoms in cometary atmospheres. The analysis is based on 48 high-resolution and high signal-to-noise spectra collected with UVES at the ESO VLT between 2003 and 2011 referring to 12 comets of different origins observed at various heliocentric distances. The flux ratio of the green line to the sum of the two red lines is evaluated to determine the parent species of the oxygen atoms by comparison with theoretical models. This analysis confirms that, at about 1 AU, H[SUB]2[/SUB]O is the main parent molecule producing oxygen atoms. At heliocentric distances >2.5 AU, this ratio changes rapidly, an indication that other molecules are starting to contribute. The most abundant species after H[SUB]2[/SUB]O in the coma, CO and CO[SUB]2[/SUB], are good candidates, and the ratio is used to estimate their abundances. We found that the CO[SUB]2[/SUB] abundance relative to H[SUB]2[/SUB]O in comet C/2001 Q4 (NEAT) observed at 4 AU can be as high as ~70%. The intrinsic widths of the oxygen lines were also measured. The green line is on average about 1 km s[SUP]-1[/SUP] broader than the red lines, while the theory predicts that the red lines are broader. This might be due to the nature of the excitation source or to a contribution of CO[SUB]2[/SUB] as the parent molecule of the 5577.339 Å line. At 4 AU, we found that the width of the green and red lines in comet C/2001 Q4 are the same, which could be explained if CO[SUB]2[/SUB] becomes the main contributor to the three [OI] lines at high heliocentric distances. Based on observations made with ESO Telescope at the La Silla Paranal Observatory under programs ID 268.C-5570, 270.C-5043, 073.C-0525, 274.C-5015, 075.C-0355, 080.C-0615, 280.C-5053, 086.C-0958, and 087.C-0929. [less ▲]

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See detailVirtual Reality as a Complementary Therapy to Sexual Addiction Treatment
Cismaru Inescu, Adina ULg; Andrianne, Robert ULg; Triffaux, Jean-Marc ULg

in International Journal of Advanced Computer Science (2013), 3(7),

Virtual reality has gained traction as a research, education and treatment tool. Virtual reality is a system that immerses people in virtual worlds and improves clinicians’ traditional treatments for ... [more ▼]

Virtual reality has gained traction as a research, education and treatment tool. Virtual reality is a system that immerses people in virtual worlds and improves clinicians’ traditional treatments for addictive disorders, eating disorders, phobias, and stroke rehabilitation. Sex addiction is a dysregulation of sexual desire, characterized by excessive sexual behavior (between 5-15 sexual activities/day, for more than 6 months, after the age of 15). Hypersexuality highlights disturbances in human sexual desire, motivation, and behavior systems. Virtual reality worlds were initially designed to treat smokers and alcoholics, and are now programmed for drug users and other kind of addictions. In this article we present different characteristics of sex addiction and possible treatments, including the virtual exposure treatment. [less ▲]

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See detailFast-evolving weather for the coolest of our two new substellar neighbours
Gillon, Michaël ULg; Triaud, A. H. M. J.; Jehin, Emmanuel ULg et al

in Astronomy and Astrophysics (2013), 555

We present the results of an intense photometric monitoring in the near-infrared (~0.9 microns) with the TRAPPIST robotic telescope of the newly discovered binary brown dwarf WISE J104915.57-531906.1, the ... [more ▼]

We present the results of an intense photometric monitoring in the near-infrared (~0.9 microns) with the TRAPPIST robotic telescope of the newly discovered binary brown dwarf WISE J104915.57-531906.1, the third closest system to the Sun at a distance of only 2 pc. Our twelve nights of photometric time-series reveal a quasi-periodic (P = 4.87+-0.01 h) variability with a maximal peak-peak amplitude of ~11% and strong night-to-night evolution. We attribute this variability to the rotational modulation of fast-evolving weather patterns in the atmosphere of the coolest component (~T1-type) of the binary. No periodic signal is detected for the hottest component (~L8-type). For both brown dwarfs, our data allow us to firmly discard any unique transit during our observations for planets >= 2 Rearth. For orbital periods smaller than ~9.5 h, transiting planets are excluded down to an Earth-size. [less ▲]

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See detailEstimating the parameters of globular cluster M 30 (NGC 7099) from time-series photometry
Kains, N.; Bramich, D. M.; Arellano Ferro, A. et al

in Astronomy and Astrophysics (2013), 555

<BR /> Aims: We present the analysis of 26 nights of V and I time-series observations from 2011 and 2012 of the globular cluster M 30 (NGC 7099). We used our data to search for variable stars in this ... [more ▼]

<BR /> Aims: We present the analysis of 26 nights of V and I time-series observations from 2011 and 2012 of the globular cluster M 30 (NGC 7099). We used our data to search for variable stars in this cluster and refine the periods of known variables; we then used our variable star light curves to derive values for the cluster's parameters. <BR /> Methods: We used difference image analysis to reduce our data to obtain high-precision light curves of variable stars. We then estimated the cluster parameters by performing a Fourier decomposition of the light curves of RR Lyrae stars for which a good period estimate was possible. We also derived an estimate for the age of the cluster by fitting theoretical isochrones to our colour-magnitude diagram (CMD). <BR /> Results: Out of 13 stars previously catalogued as variables, we find that only 4 are bona fide variables. We detect two new RR Lyrae variables, and confirm two additional RR Lyrae candidates from the literature. We also detect four other new variables, including an eclipsing blue straggler system, and an SX Phoenicis star. This amounts to a total number of confirmed variable stars in M 30 of 12. We perform Fourier decomposition of the light curves of the RR Lyrae stars to derive cluster parameters using empirical relations. We find a cluster metallicity [Fe/H][SUB]ZW[/SUB] = -2.01 ± 0.04, or [Fe/H][SUB]UVES[/SUB] = -2.11 ± 0.06, and a distance of 8.32 ± 0.20 kpc (using RR0 variables), 8.10 kpc (using one RR1 variable), and 8.35 ± 0.42 kpc (using our SX Phoenicis star detection in M 30). Fitting isochrones to the CMD, we estimate an age of 13.0 ± 1.0 Gyr for M 30. This work is based on data collected by MiNDSTEp with the Danish 1.54 m telescope at the ESO La Silla Observatory.The full light curves, an extract of which is shown in Table 2 are only available at the CDS via anonymous ftp to <A href="http://cdsarc.u-strasbg.fr">http://cdsarc.u-strasbg.fr</A> (ftp://130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A36">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A36</A>Tables 8-10, and Figs. 6 and 9 are available in electronic form at <A href="http://www.aanda.org">http://www.aanda.org</A> [less ▲]

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See detailFactors affecting Tan Spot on winter wheat in the Grand-Duchy of Luxembourg
El Jarroudi, Moussa ULg; Kouadio, Louis; Beyer, Marco et al

in Journal of Plant Pathology [=JPP] (2013), s1

Tan spot caused by Drechslera tritici-repentis was identified for the first time in the Grand-Duchy of Luxembourg (GDL) in 1999 on the basis of morphological characters. In order to optimize disease ... [more ▼]

Tan spot caused by Drechslera tritici-repentis was identified for the first time in the Grand-Duchy of Luxembourg (GDL) in 1999 on the basis of morphological characters. In order to optimize disease control measures in this country, tillage methods, cultivar resistance, and fungicides effects were investigated during 1999-2009 in four sites. Over this period, only three years (i.e. 1999, 2000, and 2009) with epidemic outbreak were recorded. Field experiments showed a significant difference in disease severity between sites (P < 0.001), cultivars (P < 0.0001) and years (P < 0.001). In years with epidemic outbreak, the interaction of cultivars with non-inversion tillage, intensive winter wheat production, and favorable weather conditions caused an early outbreak of the disease and a significant severity at growth stage 83 (early dough). Non-inversion tillage was found to be a major factor increasing the tan spot severity compared to conventional tillage. Furthermore, the analysis revealed that the disease severity was related to the cultivar’s susceptibility. For cultivars with similar phenology, the severity differed between the cultivar with the highest and the one with ne lowest susceptibility by a factor of two to four. The study also showed that no fungicide (mix of triazoles and strobilurins) effect was observed in the epidemic years, except in 2000. [less ▲]

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See detailX-ray properties of the young open clusters HM1 and IC 2944/2948
Nazé, Yaël ULg; Rauw, Grégor ULg; Sana, H. et al

in Astronomy and Astrophysics (2013), 555

Using XMM-Newton data, we study for the first time the X-ray emission of HM1 and IC 2944/2948. Low-mass, pre-main-sequence objects with an age of a few Myr are detected, as well as a few background or ... [more ▼]

Using XMM-Newton data, we study for the first time the X-ray emission of HM1 and IC 2944/2948. Low-mass, pre-main-sequence objects with an age of a few Myr are detected, as well as a few background or foreground objects. Most massive stars in both clusters display the usual high-energy properties of that type of objects, though with log [L[SUB]X[/SUB]/L[SUB]BOL[/SUB]] apparently lower in HM1 than in IC 2944/2948. Compared with studies of other clusters, it seems that a low signal-to-noise ratio at soft energies, due to the high extinction, may be the main cause of this difference. In HM1, the two Wolf-Rayet stars show contrasting behaviors: WR89 is extremely bright, but much softer than WR87. It remains to be seen whether wind-wind collisions or magnetically confined winds can explain these emissions. In IC 2944/2948, the X-ray sources concentrate around HD 101205; a group of massive stars to the north of this object is isolated, suggesting that there exist two subclusters in the field-of-view. Tables 2, 5, and Figs. 5, 9 are available in electronic form at <A href="http://www.aanda.org">http://www.aanda.org</A>Based on observations collected with XMM-Newton, an ESA Science Mission with instruments and contributions directly funded by ESA Member States and the USA (NASA).Tables 1, 3 and 4 are only available at the CDS via anonymous ftp to <A href="http://cdsarc.u-strasbg.fr">http://cdsarc.u-strasbg.fr</A> (ftp://130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A83">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/555/A83</A> [less ▲]

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See detailTransiting exoplanets from the CoRoT space mission. XXIV. CoRoT-25b and CoRoT-26b: two low-density giant planets
Almenara, J. M.; Bouchy, F.; Gaulme, P. et al

in Astronomy and Astrophysics (2013), 555

We report the discovery of two transiting exoplanets, CoRoT-25b and CoRoT-26b, both of low density, one of which is in the Saturn mass-regime. For each star, ground-based complementary observations ... [more ▼]

We report the discovery of two transiting exoplanets, CoRoT-25b and CoRoT-26b, both of low density, one of which is in the Saturn mass-regime. For each star, ground-based complementary observations through optical photometry and radial velocity measurements secured the planetary nature of the transiting body and allowed us to fully characterize them. For CoRoT-25b we found a planetary mass of 0.27 ± 0.04 M[SUB]Jup[/SUB], a radius of 1.08[SUB]-0.10[/SUB][SUP]+0.3[/SUP] R[SUB]Jup[/SUB] and hence a mean density of 0.15[SUB]-0.06[/SUB][SUP]+0.15[/SUP] g cm[SUP]-3[/SUP]. The planet orbits an F9 main-sequence star in a 4.86-day period, that has a V magnitude of 15.0, solar metallicity, and an age of 4.5[SUB]-2.0[/SUB][SUP]+1.8[/SUP]-Gyr. CoRoT-26b orbits a slightly evolved G5 star of 9.06 ± 1.5-Gyr age in a 4.20-day period that hassolar metallicity and a V magnitude of 15.8. With a mass of 0.52 ± 0.05 M[SUB]Jup[/SUB], a radius of 1.26[SUB]-0.07[/SUB][SUP]+0.13[/SUP] R[SUB]Jup[/SUB], and a mean density of 0.28[SUB]-0.07[/SUB][SUP]+0.09[/SUP] g cm[SUP]-3[/SUP], it belongs to the low-mass hot-Jupiter population. Planetary evolution models allowed us to estimate a core mass of a few tens of Earth mass for the two planets with heavy-element mass fractions of 0.52[SUB]-0.15[/SUB][SUP]+0.08[/SUP] and 0.26[SUB]-0.08[/SUB][SUP]+0.05[/SUP], respectively, assuming that a small fraction of the incoming flux is dissipated at the center of the planet. In addition, these models indicate that CoRoT-26b is anomalously large compared with what standard models could account for, indicating that dissipation from stellar heating could cause this size. The CoRoT space mission, launched on December 27th 2006, has been developed and is operated by CNES, with the contribution of Austria, Belgium, Brazil, ESA (RSSD and Science Programme), Germany and Spain. Partly based on observations obtained at the European Southern Observatory at Paranal and La Silla, Chile in programs 083.C-0690(A), 184.C-0639. [less ▲]

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See detailHD 45314: a new γ Cassiopeiae analog among Oe stars
Rauw, Grégor ULg; Nazé, Yaël ULg; Spano, M. et al

in Astronomy and Astrophysics (2013), 555

Context. Oe stars possibly form an extension to higher temperatures of the Be phenomenon, but it is still unclear whether these stars have disks. <BR /> Aims: X-ray spectra could provide hints for ... [more ▼]

Context. Oe stars possibly form an extension to higher temperatures of the Be phenomenon, but it is still unclear whether these stars have disks. <BR /> Aims: X-ray spectra could provide hints for interactions of the star with a putative surrounding disk. <BR /> Methods: We obtained XMM-Newton observations of two Oe stars, HD 45314 and HD 60848. Spectra and light curves were extracted and analysed. Optical spectra were also obtained to support the X-ray observations. <BR /> Results: We find that both stars display very different X-ray properties. Whilst HD 60848 has an X-ray spectrum and emission level typical for its spectral type, HD 45314 displays a very hard X-ray emission, dominated by a thermal plasma with kT ~ 21 keV. Furthermore, HD 45314 displays count rate variations by a factor 2 on timescales of ~ 10[SUP]3[/SUP] s and a high log (L[SUB]X[/SUB]/L[SUB]bol[/SUB]) = -6.10 ± 0.03. <BR /> Conclusions: The X-ray properties of HD 45314 indicate that this star is a new member of the class of γ Cas analogs, the first one among the original category of Oe stars. Based on observations collected with XMM-Newton, an ESA Science Mission with instruments and contributions directly funded by ESA Member States and the USA (NASA), and observations collected at the European Southern Observatory (La Silla, Chile) and the Observatoire de Haute Provence (France). [less ▲]

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See detailThrombose portale étendue chez un patient sous anti-vitamine K
LEDOUBLE, Vinciane ULg; BECK, Emmanuel ULg; PETERS, Pierre ULg et al

in Revue Médicale de Liège (2013), (68(7-8)), 382-6

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See detailSocietal Vulnerability and Adolescent offending: The role of violent values, self-control and troublesome youth group involvement
Vettenburg, Nicole; Brondeel, Ruben; Gavray, Claire ULg et al

in European Journal of Criminology (2013), 10(4), 444-461

confirmation du rôle joué par le contact négatif avec les institutions sociales sur les attitudes et comportements des jeunes, et cela même si on contrôle le niveau et contrôle de soi ou d'adhésion aux ... [more ▼]

confirmation du rôle joué par le contact négatif avec les institutions sociales sur les attitudes et comportements des jeunes, et cela même si on contrôle le niveau et contrôle de soi ou d'adhésion aux valeurs violentes [less ▲]

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See detailLes spécificités managériales dans les entreprises sociales : une démarche européenne par la gestion des compétences
Cuénoud, Thibault; Moreau, Charlotte ULg; Mertens de Wilmars, Sybille ULg

in Revue Internationale de l'Economie Sociale : Recma, Revue des Etudes Coopératives, Mutualistes et Associatives (2013), 329

Few studies have looked at the nature of management in social enterprises, organisations that combine social objectives and economic constraints. How can they embrace their values in increasingly ... [more ▼]

Few studies have looked at the nature of management in social enterprises, organisations that combine social objectives and economic constraints. How can they embrace their values in increasingly difficult economic and financial times? Governance defines the overall strategy of a firm, which in turn determines the management style in relation to the parties involved. The argument put forward in this article is based on an underlying assumption that managing a social enterprise draws on specific competencies. The hypothesis was empirically validated among experts and professionals from the sector participating in the European project Leonardo Ariadne. A list of skills was assembled as a framework for this approach to facilitate the development of training courses in this area. [less ▲]

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See detailEvaluation of the residual solvent content of counterfeit tablets and capsules
Deconinck, Eric; Canfyn, Michael; Sacre, Pierre-Yves ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2013), 81-82

A group of counterfeit samples of Viagra® and Cialis® were screened for their residual solvent content and compared to the content of the genuine products. It was observed that all counterfeit samples had ... [more ▼]

A group of counterfeit samples of Viagra® and Cialis® were screened for their residual solvent content and compared to the content of the genuine products. It was observed that all counterfeit samples had higher residual solvent contents compared to the genuine products. A more diverse range of residual solvents was found as well as higher concentrations. In general these concentrations did not exceed the international imposed maximum limits. Only in a few samples the limits were exceeded. A Projection Pursuit analysis revealed clusters of samples with similar residual solvent content, possibly enabling some future perspectives in forensic research. [less ▲]

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See detailProduction at the Curie Level of No-Carrier-Added 6-18F-Fluoro-L-Dopa
Libert, Lionel ULg; Franci, Xavier; Plenevaux, Alain ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (2013), 54(7), 1154-1161

6-18F-fluoro-L-dopa (18F-FDOPA) has proven to be a useful radiopharmaceutical for the evaluation of presynaptic dopaminergic function using PET. In comparison to electrophilic synthesis, the no-carrier ... [more ▼]

6-18F-fluoro-L-dopa (18F-FDOPA) has proven to be a useful radiopharmaceutical for the evaluation of presynaptic dopaminergic function using PET. In comparison to electrophilic synthesis, the no-carrier-added (NCA) nucleophilic method has several advantages. These include much higher available activity and specific activity. Recently, we have described an NCA enantioselective synthesis using a chiral phase-transfer catalyst. However, some chemicals were difficult to implement into a commercially available synthesizer, restricting access to this radiopharmaceutical to only a few PET centers. Methods: In this paper, 2 important chemical improvements are proposed to simplify production of 18F-FDOPA, resulting in straightforward automation of the synthesis in a commercially available module. Results: First, a fast, simple, and reliable synthesis of 2-18F-fluoro-4,5-dimethoxybenzyl iodide on a solid phase support was developed. Second, a phase-transfer catalyst alkylation of a glycine derivative at room temperature was used to enable enantioselective carbon–carbon bond formation. After hydrolysis and high-performance liquid chromatography purification, a high enantiomeric excess of 18F-FDOPA (~97%) was obtained using a chiral catalyst available from a biphenyl 3 substrate. The total synthesis time was 63 min, and the decay-corrected radiochemical yield was 36% +/- 3% (n = 8). Conclusion: By exploiting the advantages of this NCA approach, using a starting activity of 185 GBq of NCA 18F-fluoride, high activities of 18F-FDOPA (> 45 GBq) with high specific activity (>753 GBq/mmol) are now available at the end of synthesis for use in clinical investigations. [less ▲]

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See detailOn the Potential of Recommendation Technologies for Efficient Content Delivery Networks
Kaafar, Mohamed Ali; Berkovsky, Shlomo; Donnet, Benoît ULg

in Computer Communication Review (2013), 43(3), 74-77

During the last decade, we have witnessed a substantial change in content delivery networks (CDNs) and user access paradigms. If previously, users consumed content from a central server through their ... [more ▼]

During the last decade, we have witnessed a substantial change in content delivery networks (CDNs) and user access paradigms. If previously, users consumed content from a central server through their personal computers, nowadays they can reach a wide variety of repositories from virtually everywhere using mobile devices. This results in a considerable time-, location-, and event-based volatility of content popularity. In such a context, it is imperative for CDNs to put in place adaptive content management strategies, thus, improving the quality of services provided to users and decreasing the costs. In this paper, we introduce predictive content distribution strategies inspired by methods developed in the Recommender Systems area. Specifically, we outline different content placement strategies based on the observed user consumption patterns, and advocate their applicability in the state of the art CDNs. [less ▲]

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See detailOptimization of the formation of vinyldithiins, therapeutic compounds from garlic
DETHIER, Bérénice ULg; Hanon, Emilien; Maayoufi, Said et al

in European Food Research & Technology (2013), 237(1), 83-88

Allyl sulfides, ajoenes and vinyldithiins are the three main groups of volatile organosulfur compounds that are formed when garlic is crushed. The manner garlic is processed (nature of the extraction ... [more ▼]

Allyl sulfides, ajoenes and vinyldithiins are the three main groups of volatile organosulfur compounds that are formed when garlic is crushed. The manner garlic is processed (nature of the extraction medium, temperature…) has a major influence on their relative proportion and the amounts produced. It has been proven recently that the vinyldithiins are at the origin of garlic’s capacity to prevent adipocytes development. Their incorporation in garlic-based nutraceuticals is thus particularly interesting. In this context, this work aims to optimize the production of vinyldithiins from garlic. After having determined the best garlic origin (Spanish) and the best oil for the extraction (olive or sunflower oil), the extraction conditions were optimized (1/2 (w/w garlic oil), 37 °C, 6 h) and 133 mg of vinyldithiins was obtained from 100 g of fresh garlic. Carrying out the extraction under microwave irradiation allowed increasing the yield 3.6-fold (yield 486 mg of vinyldithiins from 100 g of fresh garlic). This study may also contribute to the development of new garlic derived high value products by enhancing the comprehension of their formation. [less ▲]

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See detailStable higher order finite-difference schemes for stellar pulsation calculations
Reese, Daniel ULg

in Astronomy and Astrophysics (2013), 555

Context: Calculating stellar pulsations requires a sufficient accuracy to match the quality of the observations. Many current pulsation codes apply a second order finite-difference scheme, combined with ... [more ▼]

Context: Calculating stellar pulsations requires a sufficient accuracy to match the quality of the observations. Many current pulsation codes apply a second order finite-difference scheme, combined with Richardson extrapolation to reach fourth order accuracy on eigenfunctions. Although this is a simple and robust approach, a number of drawbacks exist thus making fourth order schemes desirable. A robust and simple finite-difference scheme, which can easily be implemented in either 1D or 2D stellar pulsation codes is therefore required. Aims: One of the difficulties in setting up higher order finite-difference schemes for stellar pulsations is the so-called mesh-drift instability. Current ways of dealing with this defect include introducing artificial viscosity or applying a staggered grids approach. However these remedies are not well-suited to eigenvalue problems, especially those involving non-dissipative systems, because they unduly change the spectrum of the operator, introduce supplementary free parameters, or lead to complications when applying boundary conditions. Methods: We propose here a new method, inspired from the staggered grids strategy, which removes this instability while bypassing the above difficulties. Furthermore, this approach lends itself to superconvergence, a process in which the accuracy of the finite differences is boosted by one order. Results: This new approach is successfully applied to stellar pulsation calculations, and is shown to be accurate, flexible with respect to the underlying grid, and able to remove mesh-drift. Conclusions: Although specifically designed for stellar pulsation calculations, this method can easily be applied to many other physical or mathematical problems. [less ▲]

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See detailA New Method for Quality by Design Robust Optimization in Liquid Chromatography
Debrus, Benjamin ULg; Lebrun, Pierre ULg; Rozet, Eric ULg et al

in LC-GC Europe (2013), -(-), -

A new method to optimize liquid chromatography (LC) methods using a Quality by Design (QbD) approach is presented. This method is based on the use of design of experiments (DOE) and independent component ... [more ▼]

A new method to optimize liquid chromatography (LC) methods using a Quality by Design (QbD) approach is presented. This method is based on the use of design of experiments (DOE) and independent component analysis (ICA) to accurately estimate the modelled responses (that is, the retention times at the beginning, the apex, and the end) of each peak, even for coeluted peaks. The modelling of these responses usesmultiple linear regressions, while the propagation of the error affecting the responses and coming from the models is carried out by Monte Carlo simulation. The design space is determined as the region of assay factors where the probability to reach baseline-resolved peaks is higher than the desired level of quality. This method was applied to the optimization of the separation of nine compounds in a mixture, yielding the design space and the demonstration of robustness of the method. Finally, the method was validated. [less ▲]

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See detailAscl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish
Flasse, Lydie; Pirson, Justine; Stern, David ULg et al

in BMC Biology (2013), 11

Background NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that ... [more ▼]

Background NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state. Results We show herein that, in zebrafish, neurog3 is not expressed in the pancreas and null neurog3 mutant embryos do not display any apparent endocrine defects. The control of endocrine cell fate is instead fulfilled by a couple of bHLH factors, Ascl1b and Neurod1, that are both repressed by Notch signaling. ascl1b is transiently expressed in the mid-trunk endoderm just after gastrulation and is required for the generation of the first pancreatic endocrine precursor cells. Neurod1 is expressed afterwards in the pancreatic anlagen and pursues the endocrine cell differentiation program initiated by Ascl1b. Their complementary role in endocrine differentiation of the dorsal bud is demonstrated by the loss of all hormone-secreting cells following their simultaneous inactivation. This defect is due to a blockage of the initiation of endocrine cell differentiation. Conclusions This study demonstrates that NEUROG3 is not the unique pancreatic endocrine cell fate determinant in vertebrates. A general survey of endocrine cell fate determinants in the whole digestive system among vertebrates indicates that they all belong to the ARP/ASCL family but not necessarily to the Neurog3 subfamily. The identity of the ARP/ASCL factor involved depends not only on the organ but also on the species. One could therefore consider differentiating stem cells into insulin-producing cells without the involvement of NEUROG3 but via another ARP/ASCL factor. [less ▲]

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See detailEVOLVE: entre déception et optimisme
DELANAYE, Pierre ULg; Krzesinski, Jean-Marie ULg; CAVALIER, Etienne ULg

in Néphrologie & Thérapeutique (2013), 9(4), 241-245

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See detailLES ENCLOS-EXCLOS : UNE TECHNIQUE ÉPROUVÉE POUR L’ÉVALUATION ET LE MONITORING DE L’ÉQUILIBRE FORÊT-GRANDE FAUNE
Lehaire, François ULg; Morelle, Kevin ULg; Licoppe, Alain ULg et al

in Forêt Wallonne (2013), 125

During the last decades, populations of large ungulate herbivores have increased and their influence on forest vegetation have been clearly highlighted. Therefore, monitoring game pressure have become ... [more ▼]

During the last decades, populations of large ungulate herbivores have increased and their influence on forest vegetation have been clearly highlighted. Therefore, monitoring game pressure have become unavoidable for sustainable forest management. Such monitoring require a rigorous approach in order to evaluate objectively the forest-game balance. Under these conditions, the use of exclosure experiment has appeared an interesting solution. They enable to observe the ecosystem evolution due to forest-game imbalance as well as to detect any early deterioration of a situation that was initially considered acceptable. The enclosure-exclosure devices compare, on the one hand, the real environment (exclosure) fully accessible by wildlife and, secondly, a “control” fenced habitat (enclosures) inaccessible to all populations of large ungulates (e.g. wild boar, red deer, roe deer and mouflon). In 2006, enclosure-exclosure devices (4 x 4 m) were installed within forest gaps in order to monitore the understory dynamic in Wallonia. Observations were collected until 2012 and we computed a set of indicators characterizing the ecological changes due to large herbivores pressure on forest ecosystems. Such devices played a key educational role as it provide a visual comparison of two contrasted situations. Additionally, quantitative information were collected to perform further analysis (floristic survey, as well as height, number of stems and the cover of vegetation). We identified indicators of the ecological changes that responded within two years whereas other indicators required at least 4 monitoring years in order to quantify correctly herbivore pressure. Short-term indicators allow a rapid detection, but they have the disadvantage of being very sensitive to exogenous factors (climate changes, site conditions). At the opposite, medium-term indicators, such as regeneration growth, require a longer monitoring period, but they are more robust (mitigation interannual variations of environmental factors) than the short-term indicators. We evaluated the relative efficiency of various indicators using 17 enclosures distributed in two zones with contrasted deer densities. Some of the tested indicators allowed detecting significant differences between the two zones (Student's t test). In particular, among the short-term indicators we obtained significant result with the ground vegetation richness, regeneration richness, seedling density and height of Rubus fruticosus L. and Rubus idaeus L.. Among the medium-term indicators, the most relevant indicators were the average height of beech and birch, ground vegetation richness, seedling density and total cover of vegetation. [less ▲]

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See detailFinding the Roots of Adolescent Aggressive Behavior: A Test of Three Developmental Pathways
Glowacz, Fabienne ULg; Véronneau, Marie-Hélène; Boët, Sylvie et al

in International Journal of Behavioral Development (2013), 37(4), 319-331

Aggressive behaviors in adolescence often originate in early development. This study tested three longitudinal pathways starting in early childhood, in a sample of 325 Belgian participants (162 girls ... [more ▼]

Aggressive behaviors in adolescence often originate in early development. This study tested three longitudinal pathways starting in early childhood, in a sample of 325 Belgian participants (162 girls) assessed every 1 or 2 years from birth through age 14. Structural equation models supported the “mother early dissatisfaction” pathway toward adolescent aggression, but neither the “cognitive functioning” nor the “early aggressive behavior” pathway gained clear support. Mother’s early dissatisfaction with her child was the starting point of a series of negative perceptions of the child, which predicted physical and social aggression in adolescence. Children’s cognitive functioning and early aggression level were weakly correlated with mother’s perceptions. This finding suggests that explaining normative development to parents may improve mothers’ perceptions of their early experience as a mother, of their child, and of their subsequent interactions, which may reduce their child’s future aggressive behaviors. [less ▲]

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