Conclusions: The detection of a low-mass companion inside a massive debris disc makes this system an analog of other young planetary systems such as β Pictoris, HR 8799 or HD 95086 and requires now further characterisation of both components to understand their interactions. [less ▲]Detailed reference viewed: 40 (4 ULiège) Study of the variability of Nova V5668 Sgr, based on high-resolution spectroscopic monitoringJack, D.; Robles Pérez, J. De J.; De Gennaro Aquino, I. et alin Astronomische Nachrichten (2017), 338We present results of our dense spectroscopic monitoring of Nova V5668 Sgr. Starting on March 19 in 2015, only a few days after discovery, we have obtained a series of spectra with the TIGRE telescope and ... [more ▼]We present results of our dense spectroscopic monitoring of Nova V5668 Sgr. Starting on March 19 in 2015, only a few days after discovery, we have obtained a series of spectra with the TIGRE telescope and its HEROS echelle spectrograph which offers a resolution of R = 20,000 and covers the optical wavelength range from 3800 to 8800 {\AA}. We performed a line identification of the discernible features for four spectra which are representative for the respective phases in the light curve evolution of that nova. By simultaneously analysing the variations in the visual light curve and the corresponding spectra of Nova V5668 Sgr, we found that during the declining phases of the nova the absorption features in all hydrogen and many other lines had shifted to higher expansion velocities of -2000 km s^-1. Conversely, during the rise towards the following maximum, these observed absorption features had returned to lower expansion velocities.We found that the absorption features of some Fe II lines displayed the same behaviour, but in addition disappeared for a few days during some declining phases. Features of several N I lines also disappeared while new N II lines appeared in emission for a few days during some of the declining phases of the light curve of Nova V5668 Sgr. The shape of the emission features is changing during the evolution and shows a clear double peak structure after the deep minimum. [less ▲]Detailed reference viewed: 6 (0 ULiège) Hot-Melt Extrusion as a Continuous Manufacturing Process to Form Ternary Cyclodextrin Inclusion ComplexesThiry, Justine ; Krier, Fabrice; Ratwatte, Shenelka et alin European Journal of Pharmaceutical Sciences (2017), 96Detailed reference viewed: 49 (6 ULiège) The EACVI Echo Handbook.Nchimi Longang, Alain in European Heart Journal (2017)Detailed reference viewed: 12 (1 ULiège) First limits on the occurrence rate of short-period planets orbiting brown dwarfsHe, Matthias Y.; Triaud, Amaury H. M. J.; Gillon, Michaël in Monthly Notices of the Royal Astronomical Society (2017), 464Planet formation theories predict a large but still undetected population of short-period terrestrial planets orbiting brown dwarfs. Should specimens of this population be discovered transiting relatively ... [more ▼]Planet formation theories predict a large but still undetected population of short-period terrestrial planets orbiting brown dwarfs. Should specimens of this population be discovered transiting relatively bright and nearby brown dwarfs, the Jupiter-size and the low luminosity of their hosts would make them exquisite targets for detailed atmospheric characterisation with JWST and future ground-based facilities. The eventual discovery and detailed study of a significant sample of transiting terrestrial planets orbiting nearby brown dwarfs could prove to be useful not only for comparative exoplanetology but also for astrobiology, by bringing us key information on the physical requirements and timescale for the emergence of life. In this context, we present a search for transit-signals in archival time-series photometry acquired by the Spitzer Space Telescope for a sample of 44 nearby brown dwarfs. While these 44 targets were not particularly selected for their brightness, the high precision of their Spitzer light curves allows us to reach sensitivities below Earth-sized planets for 75% of the sample and down to Europa-sized planets on the brighter targets. We could not identify any unambiguous planetary signal. Instead, we could compute the first limits on the presence of planets on close-in orbits. We find that within a 1.28 day orbit, the occurrence rate of planets with a radius between 0.75 and 3.25 R$_\oplus$ is {\eta} < 67 $\pm$ 1%. For planets with radii between 0.75 and 1.25 R$_\oplus$, we place a 95% confident upper limit of {\eta} < 87 $\pm$ 3%. If we assume an occurrence rate of {\eta} = 27% for these planets with radii between 0.75 and 1.25 R$_\oplus$, as the discoveries of the Kepler-42b and TRAPPIST-1b systems would suggest, we estimate that 175 brown dwarfs need to be monitored in order to guarantee (95%) at least one detection. [less ▲]Detailed reference viewed: 43 (0 ULiège) Water loss from terrestrial planets orbiting ultracool dwarfs: implications for the planets of TRAPPIST-1Bolmont, E.; Selsis, F.; Owen, J. E. et alin Monthly Notices of the Royal Astronomical Society (2017), 464Ultracool dwarfs (UCD; $T_{\rm eff}<\sim3000~$K) cool to settle on the main sequence after $\sim$1 Gyr. For brown dwarfs, this cooling never stops. Their habitable zone (HZ) thus sweeps inward at least ... [more ▼]Ultracool dwarfs (UCD; $T_{\rm eff}<\sim3000~$K) cool to settle on the main sequence after $\sim$1 Gyr. For brown dwarfs, this cooling never stops. Their habitable zone (HZ) thus sweeps inward at least during the first Gyr of their lives. Assuming they possess water, planets found in the HZ of UCDs have experienced a runaway greenhouse phase too hot for liquid water prior to entering the HZ. It has been proposed that such planets are desiccated by this hot early phase and enter the HZ as dry worlds. Here we model the water loss during this pre-HZ hot phase taking into account recent upper limits on the XUV emission of UCDs and using 1D radiation-hydrodynamic simulations. We address the whole range of UCDs but also focus on the planets recently found around the $0.08~M_\odot$ dwarf TRAPPIST-1. Despite assumptions maximizing the FUV-photolysis of water and the XUV-driven escape of hydrogen, we find that planets can retain significant amounts of water in the HZ of UCDs, with a sweet spot in the $0.04$-$0.06~M_\odot$ range. We also studied the TRAPPIST-1 system using observed constraints on the XUV-flux. We find that TRAPPIST-1b and c may have lost as much as 15 Earth Oceans and planet d -- which might be inside the HZ -- may have lost less than 1 Earth Ocean. Depending on their initial water contents, they could have enough water to remain habitable. TRAPPIST-1 planets are key targets for atmospheric characterization and could provide strong constraints on the water erosion around UCDs. [less ▲]Detailed reference viewed: 40 (0 ULiège) H.M. Enzensberger contre l'amertume du vieillard. Des "groupes vidéos" à Youtube (et retour).Hamers, Jérémy in Cahier Louis-Lumière (2017), 10By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link ... [more ▼]By interrelating several texts on the editing and juxtaposition of heterogeneous images by the German essayist and media theorist Hans Magnus Enzensberger, this article brings up to date an aesthetic link between various past and contemporary media devices. The identification of this link makes it possible to free theoretical critique of the evolutionary paradigm of failure and progress (technological and political), opening it up to a set of reciprocal and non-linear insights. In this context, the use of Enzensberger texts also goes beyond any form of periodisation. By engaging a dialogue with his “Jeu de construction pour une théorie des medias” / Constituents of a Theory of the Media (1970), several essays gathered in Médiocrité et folie / Mediocrity and Madness (1988), as well as his recent autobiographical interview Erinnerungen an einen Tumult (2014), this text shows how criticism by the German writer, while constantly revitalised by the emergence of “new” objects (tabloid press, mobile video, television, Internet, smartphones), invites us to overcome any technological determinism to simultaneously consider the political potential of the first activist video groups and platforms dominating the Internet today. [less ▲]Detailed reference viewed: 54 (4 ULiège) How cognition affects perception: Brain activity modelling to unravel top-down dynamicsDesseilles, Martin ; Phillips, Christophe in Behavioral and Brain Sciences (2017), 39In this commentary on Firestone & Scholl's (F&S's) article, we argue that researchers should use brain-activity modelling to investigate top-down mechanisms. Using functional brain imaging and a specific ... [more ▼]In this commentary on Firestone & Scholl's (F&S's) article, we argue that researchers should use brain-activity modelling to investigate top-down mechanisms. Using functional brain imaging and a specific cognitive paradigm, modelling the BOLD signal provided new insight into the dynamic causalities involved in the influence of cognitions on perceptions. [less ▲]Detailed reference viewed: 34 (4 ULiège) Le nintedanib (OFEV) : nouveau traitement remboursé dans la fibrose pulmonaire idiopathiqueGUIOT, Julien ; CORHAY, Jean-Louis ; Louis, Renaud in Revue médico-chirugicale du CHU de Charleroi (2017), 2017-1Detailed reference viewed: 110 (0 ULiège) Relevance of vitamin D in the pathogenesis and therapy of frailty.Bruyère, Olivier ; Cavalier, Etienne ; Buckinx, Fanny et alin Current Opinion in Clinical Nutrition & Metabolic Care (2017), 20(1), 26-29PURPOSE OF REVIEW: This article reviews recently published evidence regarding the role of vitamin D in the physiopathology of physical frailty in elderly populations and its role in the management of this ... [more ▼]PURPOSE OF REVIEW: This article reviews recently published evidence regarding the role of vitamin D in the physiopathology of physical frailty in elderly populations and its role in the management of this geriatric condition. RECENT FINDINGS: Some recent studies have found a low level of 25-hydroxyvitamin D, considered the best marker of vitamin D status, in frail individuals. All prospective studies consistently report that low vitamin D status is associated with an increased risk of becoming frail. Recent studies also suggest that the relationship between vitamin D status and frailty is largely mediated by the development of sarcopenia. Very few well designed randomized controlled trials are available that assess the effectiveness of vitamin D supplementation in the prevention or management of frailty. In the absence of specific guidelines, a minimal serum 25-hydroxyvitamin D level of 75 nmol/l is proposed for frail elderly patients by some scientific societies. The doses necessary to reach this target are between 800 and 2000 IU/day. SUMMARY: Several studies suggest a potential effect of vitamin D on physical frailty but large clinical trials are lacking at this time to provide solid evidence of clinical benefit. [less ▲]Detailed reference viewed: 34 (10 ULiège) La «Health Literacy»,un moyen pour réduire les inégalités sociales de santéBragard, Isabelle ; COUCKE, Philippe ; Pétré, Benoît et alin Revue Médicale de Liège (2017), 72(1), Health literacy (HL) is defined as ‘the knowledge, motivation, and competences to access, understand, appraise and apply health information in order to make judgments and take decisions in everyday life ... [more ▼]Health literacy (HL) is defined as ‘the knowledge, motivation, and competences to access, understand, appraise and apply health information in order to make judgments and take decisions in everyday life concerning health care, disease prevention and health promotion to maintain or improve quality of life’. This concept begins to be recognized as a priority area for action at political level in Belgium. Indeed, a limited HL may affect health by leading, by example, with poorer management of chronic diseases, more hospital admissions and premature deaths. This paper addresses the question of HL evaluation, improvement interventions as well as the many challenges that remain in this area. HL seems fundamental to the development of better health management. It would allow patients to play a more active role in health care, to involve all health stakeholders, and to contribute to a more sustainable health system. Improving HL could allow better equal access to health care. [less ▲]Detailed reference viewed: 146 (6 ULiège) Reversible TAD chemistry as a convenient tool for the design of (re)processable PCL-based shape-memory materialsDefize, Thomas ; Riva, Raphaël ; Thomassin, Jean-Michel et alin Macromolecular Rapid Communications (2017), 38(1), 1600517A chemically cross-linked but remarkably (re)processable shape-memory polymer (SMP) is designed by cross-linking poly(ε -caprolactone) (PCL) stars via the efficient triazolinedione click chemistry, based ... [more ▼]A chemically cross-linked but remarkably (re)processable shape-memory polymer (SMP) is designed by cross-linking poly(ε -caprolactone) (PCL) stars via the efficient triazolinedione click chemistry, based on the very fast and reversible Alder– ene reaction of 1,2,4-triazoline-3,5-dione (TAD) with indole compounds. Typically, a six-arm star-shaped PCL function- alized by indole moieties at the chain ends is melt-blended with a bisfunctional TAD, directly resulting in a cross-linked PCL-based SMP without the need of post-curing treatment. As demonstrated by the stress relaxation measurement, the labile character of the TAD–indole adducts under stress allows for the solid-state plasticity reprocessing of the permanent shape at will by compression molding of the raw cross-linked material, while keeping excellent shape-memory properties. [less ▲]Detailed reference viewed: 55 (9 ULiège) Management of children with congenital heart defect: state of the art and future prospects.Seghaye, Marie-Christine in Future Cardiology (2017), 13(1), 65-79The treatment of children with congenital heart defects has evolved in the last 60 years from conservative care to a highly specialized management where advances in imaging, surgical, interventional and ... [more ▼]The treatment of children with congenital heart defects has evolved in the last 60 years from conservative care to a highly specialized management where advances in imaging, surgical, interventional and support techniques meet together to ensure satisfactory development and good quality of life to the child and to the upcoming grown up. Management of congenital heart defects best begins before birth with the aim, whenever possible, to maintain or establish biventricular physiology or, if this is excluded, to optimize the conditions for univentricular physiology. Current research in the field of genetics, device bioengineering and miniaturization, stem cell therapy, and fusion imaging technology is expected to help to improve further patient outcome. In this review, current management strategies and future prospects are discussed. [less ▲]Detailed reference viewed: 7 (0 ULiège) Health Outcomes of Sarcopenia: A Systematic Review and Meta-Analysis.Beaudart, Charlotte ; Zaaria, Myriam; Pasleau, Françoise et alin PLoS ONE (2017), 12(1), 0169548OBJECTIVE: The purpose of this study was to perform a systematic review to assess the short-, middle- and long-term consequences of sarcopenia. METHODS: Prospective studies assessing the consequences of ... [more ▼]OBJECTIVE: The purpose of this study was to perform a systematic review to assess the short-, middle- and long-term consequences of sarcopenia. METHODS: Prospective studies assessing the consequences of sarcopenia were searched across different electronic databases (MEDLINE, EMBASE, EBM Reviews, Cochrane Database of Systematic Reviews, EBM Reviews ACP Journal Club, EBM Reviews DARE and AMED). Only studies that used the definition of the European Working Group on Sarcopenia in Older People to diagnose sarcopenia were included. Study selection and data extraction were performed by two independent reviewers. For outcomes reported by three or more studies, a meta-analysis was performed. The study results are expressed as odds ratios (OR) with 95% CI. RESULTS: Of the 772 references identified through the database search, 17 were included in this systematic review. The number of participants in the included studies ranged from 99 to 6658, and the duration of follow-up varied from 3 months to 9.8 years. Eleven out of 12 studies assessed the impact of sarcopenia on mortality. The results showed a higher rate of mortality among sarcopenic subjects (pooled OR of 3.596 (95% CI 2.96-4.37)). The effect was higher in people aged 79 years or older compared with younger subjects (p = 0.02). Sarcopenia is also associated with functional decline (pooled OR of 6 studies 3.03 (95% CI 1.80-5.12)), a higher rate of falls (2/2 studies found a significant association) and a higher incidence of hospitalizations (1/1 study). The impact of sarcopenia on the incidence of fractures and the length of hospital stay was less clear (only 1/2 studies showed an association for both outcomes). CONCLUSION: Sarcopenia is associated with several harmful outcomes, making this geriatric syndrome a real public health burden. [less ▲]Detailed reference viewed: 31 (6 ULiège) THE LACTOPEROXIDASE SYSTEM, A NATURAL BIOCHEMICAL BIOCONTROL AGENT FOR PRE- AND POST-HARVEST APPLICATIONSBafort, Françoise ; Parisi, Olivier ; Perraudin, Jean-Paul et alin Journal of Phytopathology (2017), 165(1), 22-34Detailed reference viewed: 24 (3 ULiège) First Report of Candidatus Liberibacter solanacearum Associated with the Psyllid Bactericera trigonica Hodkinson on Carrots in Northern AfricaTahzima, R.; Massart, Sébastien ; Achbani, E.H. et alin Plant Disease (2017), 101(1), 242Detailed reference viewed: 31 (0 ULiège) Lessons learned from the virus indexing of Musa germplasm: insights from a multiyear collaborationDe Clerck, Caroline ; Crew, Kathy; Van den Houwe, Ines et alin Annals of Applied Biology (2017)The Bioversity International Transit Center (ITC) for banana hosts more than 1500 accessions largely covering the genetic diversity of the genus Musa. Its objective is to conserve this genetic diversity ... [more ▼]The Bioversity International Transit Center (ITC) for banana hosts more than 1500 accessions largely covering the genetic diversity of the genus Musa. Its objective is to conserve this genetic diversity and to supply plant materials to users worldwide. All the Musa accessions must be tested for virus presence and, if infected, virus elimination must be attempted, to enable the supply of virus-free plant material. An international collaborative effort launched under the auspices of Bioversity International (2007–2013) finally led to the implementation of a two-step process to test the accessions. The first step, called pre-indexing, involved only molecular tests and was designed as a pre-screen of new germplasm lines or existing accessions to reduce the need for post-entry virus therapy and repeated virus indexing. The second step, called full indexing, was performed on either older existing accessions or newer accessions which tested negative during pre-indexing, and involvedmolecular tests, transmission electron microscopy (TEM) and symptom observation. In total, 270 germplasm lines (434 samples) were pre-indexed; while full indexing was carried out on 243 accessions (68 of which had been pre-indexed). A significant proportion of the samples tested during pre-indexing was infected with at least one virus (68%), showing the utility of this early pre-screening step. Banana streak OL virus and Banana mild mosaic virus were the most commonly detected viruses during both pre- and full indexing. For 22 accessions, viral particles were observed by TEM in full indexing while the molecular tests were negative, underlining the importance of combining various detection techniques. After full indexing, viruses were not detected in 166 accessions, which were then released for international distribution from the ITC. This publication exemplifies how the practical application of diagnostic protocols can raise fundamental questions related to their appropriate use in routine practice and the need for their continuous monitoring and improvement after their first publication. [less ▲]Detailed reference viewed: 15 (1 ULiège) Application of discrete choice experiment to assess farmers’ willingness to report swine diseases in the Red River Delta region, VietnamPham Thi Thanh, Hoa; Peyre, Marisa; Quang Trinh, Tuyen et alin Preventive Veterinary Medicine (2017), 138A discrete choice experiment (DCE) is carried out to value socio-economic factors influencing the farmer’s decision to report swine diseases and to assess the willingness of farmers to report swine ... [more ▼]A discrete choice experiment (DCE) is carried out to value socio-economic factors influencing the farmer’s decision to report swine diseases and to assess the willingness of farmers to report swine diseases. Data were collected between March and July 2015 in two provinces in the Red River Delta, Northern Vietnam, from 196 pig producers by face-to face interview. A conditional logit model is used to measure the relative importance of the socio-economic factors and calculate the expected probability of disease reporting under changes of levels of these factors. Results of the study indicated that the likelihood of compensation and the type of culling implemented (all or only unrecovered pigs) are the two most important factors influencing farmer reporting. Compensation level, movement restriction and delay in compensation payment also have significant impacts on farmer’s decision to report animal disease but they are not as important as the above factors. Three different scenarios including changes in six different factors (attributes) are tested to predict probability of animal disease reporting. Under the current situation (uncertainty of being compensated), only 4% of the farmers would report swine disease outbreak to the official surveillance system if the culling policy involves all pigs in affected farms. This number is increased to 26% if culling in affected farms is restricted to unrecovered pigs only. Ensuring certainty of compensation increases reporting probability by up to 50% and 90% if all or only unrecovered pigs are destroyed, respectively. The results of this study are important for improving the performance and sustainability of swine disease surveillance system in Vietnam. [less ▲]Detailed reference viewed: 44 (7 ULiège) Opinion Statement ECJ-TF 2/2016 on the Decision of the Court of Justice of the European Union of 13 July 2016 in Brisal and KBC Finance Ireland (Case C-18/15), on the Admissibility of Gross Withholding Tax of InterestCFE ECJ task Force; Richelle, Isabelle in European Taxation (2017), 2017This Opinion Statement of the CFE ECJ Task Force analyses the ECJ’ s decision in Brisal and KBC Finance Ireland (Case C-18/15) of 13 July 2016. Following a Portuguese reference for a preliminary ruling ... [more ▼]This Opinion Statement of the CFE ECJ Task Force analyses the ECJ’ s decision in Brisal and KBC Finance Ireland (Case C-18/15) of 13 July 2016. Following a Portuguese reference for a preliminary ruling, the Court’ s decision provides further clarification on the permissibility of withholding taxation within the European Union. In relation to interest, the Court held that non-resident taxpayers may be subject to withholding taxes (even if comparable residents pursuing the same activity are not) but that non-residents may nevertheless not be taxed on gross income (when comparable residents are taxed on net profits) and are, therefore, entitled to deduct expenses directly connected to their business activity [less ▲]Detailed reference viewed: 21 (6 ULiège) European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: DiagnosisWERNER R. N.; NIKKELS, Arjen ; MARINOVIC B. et alin Journal of the European Academy of Dermatology & Venereology (2017), 31Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim ... [more ▼]Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localizations. This interdisciplinary guideline aims at an improvement of the outcomes of the acute HZ management concerning disease duration, acute pain and quality of life of the affected patients and at a reduction of the incidence of postherpetic neuralgia and other complications. The guideline development followed a structured and predefined process, considering the quality criteria for guidelines development as suggested by the AGREE II instrument. The steering group was responsible for the planning and the organization of the guideline development process (Division of Evidence based Medicine, dEBM). The expert panel was nominated by virtue of clinical expertise and/or scientific experience and included experts from the fields of dermatology, virology/infectiology, ophthalmology, otolaryngology, neurology and anaesthesiology. Recommendations for clinical practice were formally consented during the consensus conference, explicitly considering different relevant aspects. The guideline was approved by the commissioning societies after an extensive internal and external review process. In this first part of the guideline, diagnostic means have been evaluated. The expert panel formally consented recommendations for the management of patients with (suspected) HZ, referring to the assessment of HZ patients, considering various specific clinical situations. Users of the guideline must carefully check whether the recommendations are appropriate for the context of intended application. In the setting of an international guideline, it is generally important to consider different national approaches and legal circumstances with regard to the regulatory approval, availability and reimbursement of diagnostic and therapeutic interventions. [less ▲]Detailed reference viewed: 24 (1 ULiège) Habitat selection and reproduction of newts in networks of fish and fishless aquatic patchesWinandy, Laurane ; Legrand, Pauline ; Denoël, Mathieu in Animal Behaviour (2017), 123The spatial distribution of organisms in patchy environments can be determined by the relationship between habitat quality and animal behaviour. In species with complex life cycles, such as pond-breeding ... [more ▼]The spatial distribution of organisms in patchy environments can be determined by the relationship between habitat quality and animal behaviour. In species with complex life cycles, such as pond-breeding amphibians, the selection of a suitable wetland is crucial. While the traditional view of amphibian ecology suggests strong site fidelity and low vagility, more recent research highlights mechanisms involving active site choice through avoidance behaviour and bet-hedging strategies in heterogeneous environments. The introduction of fish to the aquatic environment is one of the factors that may alter site selection and lead to local dispersal. In this context, we investigated the habitat choice of Alpine newts, Ichthyosaura alpestris, in networks of fish (Carassius auratus) and fishless aquatic patches. Using a laboratory design consisting of aquaria divided into two water tanks connected by a terrestrial platform, we assessed newt distribution and movement between patches. During the breeding period, we compared the reproductive success of individuals in two types of networks. We found that newts escaped fish by rapidly changing aquatic patches and then aggregating in safe aquatic patches that were free of fish. In the fish network, newts maintained reproduction, but the high local abundance resulted in decreased sexual activity and egg production and increased use of the terrestrial habitat. However, in the fishless network, newts moved between aquatic patches several times, exhibited more courtship behaviour and laid more eggs than they did in the fish networks. Our results showed both adaptive habitat switching due to environmental risks in the fish network and habitat supplementation (i.e. use of alternative resources) in the fishless network. Such studies on movement behaviour and habitat selection have conservation implications in showing that the persistence of native species in invaded networks depends on the rescue effect, with immigration to fish-free habitats potentially preventing local extinction. [less ▲]Detailed reference viewed: 94 (13 ULiège) Estrogen-dependent effects of 5-hydroxytryptophan on cortical spreading depression in rat: Modelling the serotonin-ovarian hormone interaction in migraine aura.Chauvel, Virginie; Multon, Sylvie ; Schoenen, Jean in Cephalalgia : An International Journal of Headache (2017)Background: Cortical spreading depression (CSD) is the likely culprit of the migraine aura. Migraine is sexually dimorphic and thought to be a ‘‘low 5-HT’’ condition. We sought to decipher the ... [more ▼]Background: Cortical spreading depression (CSD) is the likely culprit of the migraine aura. Migraine is sexually dimorphic and thought to be a ‘‘low 5-HT’’ condition. We sought to decipher the interrelation between serotonin, ovarian hormones and cortical excitability in a model of migraine aura. Methods: Occipital KCl-induced CSDs were recorded for one hour at parieto-occipital and frontal levels in adult male (n 1⁄4 16) and female rats (n 1⁄4 64) one hour after intraperitoneal (i.p.) injection of 5-hydroxytryptophan (5-HTP) or NaCl. Sixty-five oophorectomized females were treated with estradiol- (E2) or cholesterol- (Chol) filled capsules. Two weeks later we recorded CSDs after 5-HTP/NaCl injections before or 20 hours after capsule removal. Results: 5-HTP had no effect in males, but decreased CSD frequency in cycling females, significantly so during estrus, at parieto-occipital (􏰀3.5CSD/h, p<0.001) and frontal levels (􏰀2.5CSD/h, p1⁄40.014). In oophorectomized rats, CSD susceptibility increased during E2 treatment at both recording sites (þ5CSD/h, p1⁄40.001 and þ3CSD/h, p<0.01), but decreased promptly after E2 withdrawal (􏰀4.7CSD/h, p < 0.001 and 􏰀1.7CSD/h, p 1⁄4 0.094). The CSD inhibitory effect of 5-HTP was significant only in E2-treated rats (􏰀3.4CSD/h, p 1⁄4 0.006 and 􏰀1.8CSD/h, p 1⁄4 0.029). Neither the estrous cycle phase, nor E2 or 5-HTP treatments significantly modified CSD propagation velocity. Conclusion: 5-HTP decreases CSD occurrence in the presence of ovarian hormones, suggesting its potential efficacy in migraine with aura prophylaxis in females. Elevated E2 levels increase CSD susceptibility, while estrogen withdrawal decreases CSD. In a translational perspective, these findings may explain why migraine auras can appear during pregnancy and why menstrual-related migraine attacks are rarely associated with an aura. [less ▲]Detailed reference viewed: 32 (2 ULiège) Work–Home Interface and Well-Being: A Cross-Lagged AnalysisBabic, Audrey ; Stinglhamber, Florence; Bertrand, Françoise et alin Journal of Personnel Psychology (2017), 16Detailed reference viewed: 34 (6 ULiège) Influence of the balls kinematics of axially loaded ball bearings on Coulombic frictional dissipationsBozet, Jean-Luc ; Servais, Christophe in Journal of Tribology (2017), 139(1), Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact ... [more ▼]Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact balls kinematics has still to be addressed in depth. This paper proposes a new way to calculate the balls kinematics by using a simplified quasi-static approach for dry lubricated and axially loaded ball bearings. This method does not use the classical restrictive race control assumptions. More specifically, the role played by the balls kinematics is emphasized by means of the power dissipated within contacts between balls and races. The need for a correct evaluation of the balls behavior is illustrated by using an example, viz. a ball bearing of cryogenic engine turbopump. Indeed, the dissipated power is one of the main concerns in this particular case. [less ▲]Detailed reference viewed: 45 (13 ULiège) Improving specific class mapping from remotely sensed data by cost-sensitive learningSilva, Joel; Bacao, Fernando; Dieng, Ndeye Maguette et alin International Journal of Remote Sensing (2017), 38(11), 32943316In many remote-sensing projects, one is usually interested in a small number of land-cover classes present in a study area and not in all the land-cover classes that make-up the landscape. Previous ... [more ▼]In many remote-sensing projects, one is usually interested in a small number of land-cover classes present in a study area and not in all the land-cover classes that make-up the landscape. Previous studies in supervised classification of satellite images have tackled specific class mapping problem by isolating the classes of interest and combining all other classes into one large class, usually called others, and by developing a binary classifier to discriminate the class of interest from the others. Here, this approach is called focused approach. The strength of the focused approach is to decompose the original multi-class supervised classification problem into a binary classification problem, focusing the process on the discrimination of the class of interest. Previous studies have shown that this method is able to discriminate more accurately the classes of interest when compared with the standard multi-class supervised approach. However, it may be susceptible to data imbalance problems present in the training data set, since the classes of interest are often a small part of the training set. A result the classification may be biased towards the largest classes and, thus, be sub-optimal for the discrimination of the classes of interest. This study presents a way to minimize the effects of data imbalance problems in specific class mapping using cost-sensitive learning. In this approach errors committed in theminority class are treated as being costlier than errors committed in the majority class. Cost-sensitive approaches are typically implemented by weighting training data points accordingly to their importance to the analysis. By changing the weight of individual data points, it is possible to shift theweight from the larger classes to the smaller ones, balancing the data set. To illustrate the use of the cost-sensitive approach to map specific classes of interest, a series of experiments with weighted support vector machines classifier and Landsat Thematic Mapper data were conducted to discriminate two types of mangrove forest (high-mangrove and low-mangrove) in Saloum estuary, Senegal, a United Nations Educational, Scientific and Cultural Organisation World Heritage site. Results suggest an increase in overall classification accuracy with the use of cost-sensitive method (97.3%) over the standard multi-class (94.3%) and the focused approach (91.0%). In particular, cost-sensitive method yielded higher sensitivity and specificity values on the discrimination of the classes of interest when compared with the standard multi-class and focused approaches. [less ▲]Detailed reference viewed: 13 (0 ULiège) Nullité et restitutions – À propos de la nullité d’une convention portant mise à disposition de travailleurs conclue en méconnaissance de la loi du 24 juillet 1987Daumen, Laura in Revue Générale de Droit Civil Belge = Tijdschrift voor Belgisch Burgerlijk (2017), 2017(1), 41Detailed reference viewed: 23 (5 ULiège) Les mutilations génitales féminines: la situation à LiègeSwenen, Laurie ; BRICHANT, Géraldine ; Kaluanga, Armand et alin Revue Médicale de Liège (2017), 72(1), 25-31En raison des flux migratoires actuels, le praticien obstétricien sera amené à prendre en charge des patientes porteuses de mutilations génitales féminines (MGF). Cet article reprend les principales ... [more ▼]En raison des flux migratoires actuels, le praticien obstétricien sera amené à prendre en charge des patientes porteuses de mutilations génitales féminines (MGF). Cet article reprend les principales complications obstétricales en relation avec celles-ci. Nous avons comparé un groupe de patientes ayant subi une MGF (n = 69) à un groupe contrôle (n = 162) et étudié les données concernant la patiente, la grossesse en cours, l’accouchement, le nouveau-né, le post-partum et la durée du séjour hospitalier. Dans le groupe MGF, 44 % des patientes sont porteuses de streptocoque B contre 23 % dans le groupe contrôle (p inférieur a 0,01). Concernant le périnée, dans le groupe MGF, une épisiotomie est pratiquée chez 31 % des patientes versus 35 % dans le groupe contrôle; une déchirure survient dans 42 % des accouchements par voie basse dans le groupe MGF contre 26 % dans le groupe contrôle. [less ▲]Detailed reference viewed: 13 (10 ULiège) Linking pollutant exposure of humpback whales breeding in the Indian Ocean to their feeding habits and feeding areas off AntarcticaDas, Krishna ; Malarvannan, Govindan; Dirtu, Alin et alin Environmental Pollution (2017), 220Humpback whales, Megaptera novaeangliae, breeding off la Reunion Island (Indian Ocean) undergo large-scale seasonal migrations between summer feeding grounds near Antarctica and their reproductive winter ... [more ▼]Humpback whales, Megaptera novaeangliae, breeding off la Reunion Island (Indian Ocean) undergo large-scale seasonal migrations between summer feeding grounds near Antarctica and their reproductive winter grounds in the Indian Ocean. The main scope of the current study was to investigate chemical exposure of humpback whales breeding in the Indian Ocean by providing the first published data on this breeding stock concerning persistent organic pollutants (POPs), namely polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs), DDT and its metabolites (DDTs), chlordane compounds (CHLs), polybrominated diphenyl ethers (PBDEs), and methoxylated PBDEs (MeO-PBDEs). Analyses of stable isotopes δ13C and δ15N in skin resulted in further insight in their feeding ecology, which was in agreement with a diet focused mainly on low trophic level prey species, such as krill from Antarctica. POPs were measured in all humpback whales in the order of HCB > DDTs > CHLs > HCHs > PCBs > PBDEs > MeO-BDEs. HCB (median: 24 ng.g-1 lw) and DDTs (median: 7.7 ng.g-1 lw) were the predominant compounds in all whale biopsies. Among DDT compounds, p,p’-DDE was the major organohalogenated pollutant, reflecting its long-term accumulation in humpback whales. Significantly lower concentrations of HCB and DDTs were found in females than in males (p<0.001). Other compounds were similar between the two genders (p>0.05). Differences in the HCB and DDTs suggested gender-specific transfer of some compounds to the offspring. POP concentrations were lower than previously reported results for humpback whales sampled near the Antarctic Peninsula, suggesting potential influence of their nutritional status and may indicate different exposures of the whales according to their feeding zones. Further investigations are required to assess exposure of southern humpback whales throughout their feeding zones. [less ▲]Detailed reference viewed: 63 (2 ULiège) Use of Intra-Articular Hyaluronic Acid in the Management of Knee Osteoarthritis in Clinical PracticeCooper, Cyrus; Rannou, François; Richette, Pascal et alin Arthritis Care and Research (2017), EPub ahead of printThis review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other ... [more ▼]This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intraarticular hyaluronic acid has also been highlighted based on ‘real-life’ data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions. [less ▲]Detailed reference viewed: 21 (0 ULiège) A Machine Learning-Based Approximation of Strong BranchingMarcos Alvarez, Alejandro ; Louveaux, Quentin ; Wehenkel, Louis in INFORMS Journal on Computing (2017), 29(1), 185-195We present in this paper a new generic approach to variable branching in branch-and-bound for mixed- integer linear problems. Our approach consists in imitating the decisions taken by a good branching ... [more ▼]We present in this paper a new generic approach to variable branching in branch-and-bound for mixed- integer linear problems. Our approach consists in imitating the decisions taken by a good branching strategy, namely strong branching, with a fast approximation. This approximated function is created by a machine learning technique from a set of observed branching decisions taken by strong branching. The philosophy of the approach is similar to reliability branching. However, our approach can catch more complex aspects of observed previous branchings in order to take a branching decision. The experiments performed on randomly generated and MIPLIB problems show promising results. [less ▲]Detailed reference viewed: 202 (10 ULiège) François Pétrarque, Le Petrarque en rime francoise avec ses commentaires (trad. Philippe de Maldeghem), Douai, François Fabry, 1606, 8° (Liège, Bibliothèque Alpha, XVIII.169.21 [16°])Adam, Renaud in Arm@rium Universitatis Leodiensis. La bibliothèque numérique du Moyen Âge et de la première Modernité de l’Université de Liège (2017)Detailed reference viewed: 10 (0 ULiège) Looking for phosphate-accumulating bacteria in activated sludge processes : a multidisciplinary approachTarayre, Cédric ; Charlier, Raphaëlle; Delepierre, Anissa et alin Environmental Science and Pollution Research (2017)Over the past decades, an increasing need in renewable resources has progressively appeared. This trend concerns not only fossil fuels but also mineral resources. Wastewater and sewage sludge contain ... [more ▼]Over the past decades, an increasing need in renewable resources has progressively appeared. This trend concerns not only fossil fuels but also mineral resources. Wastewater and sewage sludge contain significant concentrations in phosphate and can be considered as a fertilizer source of the utmost importance. In wastewater treatment plants, the biological uptake of phosphate is performed by a specific microbiota: the phosphate-accumulating organisms. These microorganisms are recovered in sewage sludge. Here, we aimed to investigate the occurrence of phosphate accumulators in four wastewater treatment plants. A 16S metagenetic analysis identified the main bacterial phyla extracted from the aerobic treatment: α-Proteobacteria, β-Proteobacteria, and Sphingobacteria. An enrichment stage was performed to stimulate the specific growth of phosphate-accumulating bacteria in an acetate medium. An analysis of metabolic activities of sulfur and phosphorus highlighted strong modifications related to phosphorus and much less distinguishable effects with sulfur. A solid acetate medium containing 5-Br-4-Cl-3-indolyl phosphate was used to select potential phosphate-accumulating bacteria from the enriched consortia. The positive strains have been found to belong in the genera Acinetobacter, Corynebacterium, and Pseudomonas. Finally, electron microscopy was applied to the strains and allowed to confirm the presence of polyphosphate granules. Some of these bacteria contained granules the size of which exceeded 100 nm. [less ▲]Detailed reference viewed: 47 (14 ULiège) Dynamics and emissions of N2O in groundwater: A reviewJurado Elices, Anna ; Borges, Alberto ; Brouyère, Serge in Science of the Total Environment (2017), 584-585CThis work reviews the concentrations, the dynamics and the emissions of nitrous oxide (N2O) in groundwater. N2O is an important greenhouse gas (GHG) and the primary stratospheric ozone depleting substance ... [more ▼]This work reviews the concentrations, the dynamics and the emissions of nitrous oxide (N2O) in groundwater. N2O is an important greenhouse gas (GHG) and the primary stratospheric ozone depleting substance. The major anthropogenic source that contributes to N2O generation in aquifers is agriculture because the use of fertilizers has led to the widespread groundwater contamination by inorganic nitrogen (N) (mainly nitrate, NO3−). Once in the aquifer, this inorganic N is transported and affected by several geochemical processes that produce and consume N2O. An inventory of dissolved N2O concentrations is presented and the highest dissolved concentration is about 18.000 times higher than air-equilibrated water (up to 4004 μg N L-1). The accumulation of N2O in groundwater is mainly due to denitrification and to lesser extent to nitrification. Their occurrence depend on the geochemical (e.g., NO3−, dissolved oxygen, ammonium and dissolved organic carbon) as well as hydrogeological parameters (e.g., groundwater table fluctuations and aquifer permeability). The coupled understanding of both parameters is necessary to gain insight on the dynamics and the emissions of N2O in groundwater. Overall, groundwater indirect N2O emissions seem to be a minor component of N2O emissions to the atmosphere. Further research might be devoted to evaluate the groundwater contribution to the indirect emissions of N2O because this will help to better constraint the N2O global budget and, consequently, the N budget. [less ▲]Detailed reference viewed: 57 (3 ULiège) La gestion des ressources publiques : acteurs, enjeux et processusPiron, Damien ; Weerts, Audrey ; Wintgens, Sophie in Pyramides : Revue du Laboratoire d'Etudes et de Recherches en Administration Publique (2017), 28Detailed reference viewed: 43 (5 ULiège) Self-Administration of Medicines and Dietary Supplements Among Female Amateur Runners: A Cross-Sectional Analysis.Locquet, Médéa ; Beaudart, Charlotte ; Larbuisson, Robert et alin Advances in Therapy (2017), 33(12), 2257-2268INTRODUCTION: Self-administration of medicines or dietary supplements without any physician's advice is a widespread behavior and appears to be more frequently practiced by women. Moreover, reasons to ... [more ▼]INTRODUCTION: Self-administration of medicines or dietary supplements without any physician's advice is a widespread behavior and appears to be more frequently practiced by women. Moreover, reasons to self-administer products are often pains and injuries especially among athletes who might also use remedies to improve physical performance. The objective of this study was thus to assess the prevalence of self-administration of medicines and dietary supplements as well as its determinants among female amateur runners. METHODS: Our sample was comprised of women who took part in amateur running events. Data regarding self-administration of substances, exclusively aiming at being physically prepared for the running event (i.e., intake the week before), were collected through an anonymous self-administered questionnaire including four specific themes (i.e., general information, self-administered medicines and dietary supplements, context of self-administration of substances and knowledge of the anti-doping regulations). RESULTS: A total of 136 women, with a median age of 39 years (interquartile range: 27-47), volunteered. Among them, 34.6% reported self-administration of medicines during the period immediately preceding the running event, with the aim to be physically prepared. More than one third (33.8%) also declared self-administration of dietary supplements. Furthermore, we observed that about 8.1% of the sample had consumed a potentially doping substance. After adjustments for confounding variables, the probability of self-administration of products (medicines or supplements) increased significantly with the intensity of the activity and the membership in a sports club. CONCLUSIONS: Our study showed that self-administration of products among female runners seems to be a widespread behavior, where the intensity of the sports practice and the network of runners seem to influence the decision to resort to this behavior. [less ▲]Detailed reference viewed: 49 (5 ULiège) Methane balance of an intensively grazed pasture and estimation of the enteric methane emissions from cattleDumortier, Pierre ; Aubinet, Marc ; Beckers, Yves et alin Agricultural and Forest Meteorology (2017), 232The methane turbulent fluxes of an intensively grazed pasture were measured continuously from June 2012 to December 2013 at the Dorinne Terrestrial Observatory (DTO) in Belgium. During grazing periods ... [more ▼]The methane turbulent fluxes of an intensively grazed pasture were measured continuously from June 2012 to December 2013 at the Dorinne Terrestrial Observatory (DTO) in Belgium. During grazing periods, the fluxes were dominated by enteric fermentation and were found to be strongly related to cow stocking density. In 2013, total emission from the pasture was found between 9 and 11 g CH4 m−2, 97% of which being emitted during grazing periods. Emission per LU (livestock unit) was estimated in a non-invasive way by integrating eddy covariance fluxes over large periods and by assuming a homogeneous average cattle disposition on the pasture. This estimate was compared to the one obtained during confinement periods, where cows were confined in a small part of the pasture. The emission per LU varied between 104 and 134 g CH4 LU−1 day−1 (13 and 17 g CH4 kg DMI−1), depending on the dataset and the computation method used. Diel course was characterized by two emission peaks, one in the morning and a larger one in the afternoon. For rest periods (no cattle on the pasture), small emissions were observed (median and mean values of 0.5 and 1.5 mg CH4 m−2 day−1, respectively). [less ▲]Detailed reference viewed: 76 (32 ULiège) Added value and limitations of electrical source localizationRIKIR, Estelle in Epilepsia (2017), 58(1), 174-175Detailed reference viewed: 11 (0 ULiège) Le castor, porte-parole d'une rivière vivanteDenayer, Dorothée ; Semal, Nathalie in Mille Lieux (2017), 4Detailed reference viewed: 37 (7 ULiège) Sustainability and management control. Exploring and theorizing control patterns in large European firmsCrutzen, Nathalie ; Zvezdov, Dimitar; Schaltegger, Stefanin Journal of Cleaner Production (2017), 143Detailed reference viewed: 33 (4 ULiège) L’accès des filles à l’enseignement supérieur au Burkina Faso : choix parentaux, parcours d’étudiantes et défisWouango, Joséphine in International Review of Education (2017), 63(2), Qu'est-ce qui motive les parents des milieux moins aisés à investir dans une scolarisation prolongée de leurs filles ? Qu'est-ce qui amène les filles issues de ces milieux à se maintenir dans le système ... [more ▼]Qu'est-ce qui motive les parents des milieux moins aisés à investir dans une scolarisation prolongée de leurs filles ? Qu'est-ce qui amène les filles issues de ces milieux à se maintenir dans le système scolaire jusqu'à l'université ? De nombreuses recherches sur le système éducatif burkinabé montrent qu'il existe encore des disparités entre filles et garçons à tous les niveaux, avec une aggravation de l'écart à mesure que le niveau d'études augmente. Dans ces conditions, la perspective pour des filles issues de familles moins aisées de poursuivre des études supérieures est moins certaine. Pourtant, on remarque une relative présence de filles issues de ces milieux à l'université de Ouagadougou. À partir d'une enquête qualitative auprès d'étudiantes et de leurs parents, cet article met en exergue les logiques sociales qui expliquent le parcours scolaire particulier de ces filles. Le niveau de scolarisation des aînés, la place de la fille dans la fratrie ou le souci d'équité sont des facteurs à l'origine du choix de certains parents de scolariser leurs filles. Les parents se réfèrent à plusieurs formes de justification en faveur des études universitaires des filles, parmi lesquelles la logique de fidélité des filles dans le retour de l’aide revient à de multiples reprises. Quant aux étudiantes, elles évoquent des motivations diverses pour expliquer leur parcours scolaire et universitaire, souvent émaillé de difficultés, notamment la volonté d’aider leurs parents. L’article montre en outre l’importance du soutien familial dans l’entrée des filles à l’école et à l’université, ainsi que dans la poursuite et la réussite de leurs études. [less ▲]Detailed reference viewed: 27 (2 ULiège) Vous êtes formidablesRADERMECKER, Régis in Revue de l'Association Belge du Diabète (2017), 60Detailed reference viewed: 27 (2 ULiège) Detection, isolation and characterization of Fusobacterium gastrosuis sp. nov. colonizing the stomach of pigsDe Witte, C.; Flahou, B.; Ducatelle, R. et alin Systematic & Applied Microbiology (2017), 40(1), 42-50Nine strains of a novel Fusobacterium sp. were isolated from the stomach of 6-8 months old and adult pigs. The isolates were obligately anaerobic, although they endured 2 hours exposure to air ... [more ▼]Nine strains of a novel Fusobacterium sp. were isolated from the stomach of 6-8 months old and adult pigs. The isolates were obligately anaerobic, although they endured 2 hours exposure to air. Phylogenetic analysis based on 16S rRNA and gyrase B genes demonstrated that the isolates showed high sequence similarity with Fusobacterium mortiferum, Fusobacterium ulcerans, Fusobacterium varium, Fusobacterium russii and Fusobacterium necrogenes, but formed a distinct lineage in the genus Fusobacterium. Comparative analysis of the genome of the type strain of this novel Fusobacterium sp. confirmed that it is different from other recognized Fusobacterium spp. DNA-DNA hybridization, fingerprinting and genomic %GC determination further supported the conclusion that the isolates belong to a new, distinct species. The isolates were also distinguishable from these and other Fusobacterium spp. by phenotypical characterization. The strains produced indole and exhibited proline arylamidase and glutamic acid decarboxylase activity. They did not hydrolyse esculin, did not exhibit pyroglutamic acid arylamidase, valine arylamidase, α-galactosidase, β-galactosidase, β-galactosidase-6-phosphate or α-glucosidase activity nor produced acid from cellobiose, glucose, lactose, mannitol, mannose, maltose, raffinose, saccharose, salicin or trehalose. The major fatty acids were C16 : 0 and C18 : 1ω9c. The name Fusobacterium gastrosuis sp. nov. is proposed for the novel isolates with the type strain CDW1(T) (= DSM 101753(T) = LMG 29236(T)). We also demonstrated that Clostridium rectum and Fusobacterium mortiferum represent the same species, with nomenclatural priority for the latter. [less ▲]Detailed reference viewed: 25 (5 ULiège) Multi-approach analysis to assess diet of harbour porpoises Phocoena phocoena in the southern North SeaMahfouz, C.; Meziane, T.; Henry, F. et alin Marine Ecology. Progress Series (2017), 563Detailed reference viewed: 15 (1 ULiège) Usutu virus, Belgium, 2016Garigliany, Mutien-Marie ; Linden, Annick ; Gilliaux, Gautier et alin Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (2017), 48(1), 116-119During late summer 2016, in a northwest European region extending over Belgium, the Netherlands and the eastern border of the German state of North Rhine Westphalia, an outbreak of wild bird deaths ... [more ▼]During late summer 2016, in a northwest European region extending over Belgium, the Netherlands and the eastern border of the German state of North Rhine Westphalia, an outbreak of wild bird deaths occurred similar to those reported on the continent since 1996. Dead birds were necropsied and examined by complementary methods. Pathologic and immunohistological investigations strongly suggested an infection by Usutu virus. Subsequently, genomic segments of the said virus were detected, the virus was isolated and its complete genome was sequenced. The strain, designated Usutu-LIEGE, is a close phylogenetic relative of those isolated in Germany which form a distinct group within the USUV phylogeny, the so-called Europe_3 lineage. Should this outbreak recapitulate the characteristics of those in southwest Germany in 2011 and in/around Vienna (Austria) in 2001, it is expected that specific avian populations in the affected area will face a significant reduction in size for a few years. [less ▲]Detailed reference viewed: 51 (6 ULiège) Compte rendu: AXEMAN's JAZZ et DEAD MAN'S BLUES ( Ray Celestin)Sacré, Robert in ABS Magazine (2017), (53), Detailed reference viewed: 16 (0 ULiège) Compte-rendu de l'ouvrage de Robert Ford et Bob McGrath : ZYDECO DISCOGRAPHY 1949-2010Sacré, Robert in ABS Magazine (2017), (53), Detailed reference viewed: 22 (0 ULiège) Oral contraceptive and acute intestinal ischemia with mesenteric venous thrombosis: a case reportBELIARD, Aude ; VERRETH, Lucie; GRANDJEAN, Pascalein Open Access Journal of Contraception (2017), 8Background: Venous thrombosis is a serious complication of combined contraceptive. However, mesenteric venous thrombosis and intestinal necrosis are infrequently seen in women using oral contraceptives ... [more ▼]Background: Venous thrombosis is a serious complication of combined contraceptive. However, mesenteric venous thrombosis and intestinal necrosis are infrequently seen in women using oral contraceptives and diagnosis is often delayed. Case presentation: We report a case of a 38-year-old obese female patient who presented with acute abdominal pain. A bowel infection was first diagnosed and treated with antibiotics. Contrast-enhanced tomography of the abdomen revealed diffuse ischemia of small intestine with superior mesenteric thrombosis. Laparotomy with segmental resection of both small and large bowel was performed. No predisposing factor of mesenteric venous thrombosis was demonstrated except association of combined contraceptive with obesity. Conclusion: This report highlights the need for clinicians to suspect venous mesenteric thrombosis in women of reproductive age with acute abdominal pain with poor physical findings. Detailed personal history including prescriptions should help to quickly and accurately determine the problem. [less ▲]Detailed reference viewed: 70 (2 ULiège) PrésentationDubouclez, Olivier ; Pelletier, Arnaudin Etudes Philosophiques (Les) (2017), n°1(2017), 3-5Detailed reference viewed: 17 (0 ULiège) Tracing Migrant-Mothers’ ‘Return’ Narratives in the Mexico-U.S and Peru-Belgium Migratory Circuits.Vivas Romero, Maria ; Sanchez-Martinez, Anabelain Travaux et recherches dans les amériques du centre (2017)How do contemporary migrant mothers strategize return to their home countries? And how does the social protections available for their bi-national children in sending and destination countries factor in ... [more ▼]How do contemporary migrant mothers strategize return to their home countries? And how does the social protections available for their bi-national children in sending and destination countries factor in the decision to return? Through this contribution, we aimed to tackle these questions. We draw from the analysis of two longitudinal migratory careers and argue that our participant’s return decisions were influenced both by their children’s effective access to social protection and their subjective perceptions of ‘good-motherhood’. This Trans-Atlantic comparison shows how different situated-institutional-contexts, cultures of care and motherhood resulted into different patterns of mobility for these women and their families. [less ▲]Detailed reference viewed: 30 (7 ULiège) Silicate mineralogy at the surface of MercuryNamur, Olivier ; Charlier, Bernard in Nature Geoscience (2017)NASA’s MESSENGER spacecraft has revealed geochemical diversity across Mercury’s volcanic crust. Near-infrared to ultraviolet spectra and images have provided evidence for the Fe2+-poor nature of silicate ... [more ▼]NASA’s MESSENGER spacecraft has revealed geochemical diversity across Mercury’s volcanic crust. Near-infrared to ultraviolet spectra and images have provided evidence for the Fe2+-poor nature of silicate minerals, magnesium sulfide minerals in hollows and a darkening component attributed to graphite, but existing spectral data is insufficient to build a mineralogical map for the planet. Here we investigate the mineralogical variability of silicates in Mercury’s crust using crystallization experiments on magmas with compositions and under reducing conditions expected for Mercury. We find a common crystallization sequence consisting of olivine, plagioclase, pyroxenes and tridymite for all magmas tested. Depending on the cooling rate, we suggest that lavas on Mercury are either fully crystallized or made of a glassy matrix with phenocrysts. Combining the experimental results with geochemical mapping, we can identify several mineralogical provinces: the Northern Volcanic Plains and Smooth Plains, dominated by plagioclase, the High-Mg province, strongly dominated by forsterite, and the Intermediate Plains, comprised of forsterite, plagioclase and enstatite. This implies a temporal evolution of the mineralogy from the oldest lavas, dominated by mafic minerals, to the youngest lavas, dominated by plagioclase, consistent with progressive shallowing and decreasing degree of mantle melting over time. [less ▲]Detailed reference viewed: 31 (2 ULiège) Impact of food type on respiration, fractionation and turnover of carbon and nitrogen stable isotopes in the marine amphipod Gammarus aequicauda (Martynov, 1931).Remy, François ; Darchambeau, François ; Melchior, Aurélie et alin Journal of Experimental Marine Biology & Ecology (2017), 486This study experimentally determined the impact of food source type on turnover rate and trophic enrichment factors (TEFs or ∆) of δ13C and δ15N, as well as on respiration rate, in captive populations of ... [more ▼]This study experimentally determined the impact of food source type on turnover rate and trophic enrichment factors (TEFs or ∆) of δ13C and δ15N, as well as on respiration rate, in captive populations of the marine amphipod Gammarus aequicauda. Gammarus aequicauda (318 individuals) were fed ad libitum with three food sources animal, algae, and dead Posidonia oceanica leaves (also called “litter”), varying in palatability, digestibility, nutritional qualities and isotopic compositions, for between four and six weeks in a controlled feeding experiment. The resulting death rate was lower for the amphipods fed with animal treatment (30.9%) than for individuals fed with algal (65.9%) or litter treatment (64.4%), indicating a better fitness of the individuals fed with the animal food source. Respiration rates also differed highly among the treatments. Animal treatment showed higher respiration rates than algal and litter treatments, potentially due to the toxicity of the algae and the very low nutritional quality of the litter. Amphipods fed with these treatments might have entered in a “low activity state” to cope with these unsuitable food sources, inducing low respiration rates. Due to the very low assimilation and toxicity of the algae source, turnover rate for δ13C was impossible to determine. Turnover rate for δ13C was much faster (half-life = 12.55 days) for amphipods fed with the animal food source than for amphipods fed with litter (half-life = 51.62 days), showing the faster assimilation of the most nutritionally optimal food sources by G. aequicauda. Turnover for δ15N was impossible to determine because the amphipods were already at isotopic equilibrium at the beginning of the experiment. Despite the detritus feeder status of Gammarus aequicauda, TEFs for the animal treatments were in accordance with values generally found for carnivorous organisms (∆13C = 0.9 ± 0.7‰; ∆15N = 2.9 ± 0.6‰). TEFs for the litter treatment were in accordance with values generally corresponding to detritivorous organisms (∆13C = 1.2‰; ∆15N = 1.0 ± 0.4‰). SIAR mixing model outputs obtained with these new TEF values were more constrained and coherent than outputs obtained with general literature TEFs. This study thus demonstrated the non-negligible impact of the food source on Gammarus aequicauda physiological status, fitness and turnover rates, but also on TEFs—highlighting the importance of TEF experimental calculations for every potential food source of a given organism to ensure more robust isotopic data interpretation. [less ▲]Detailed reference viewed: 66 (9 ULiège) La polémique marxiste comme pouvoir de praxis : le rôle des revues dans la radicalisation d'un imaginaire politiqueFranck, Thomas in Dacoromania Litteraria (2017), 3On the basis of Antonio Gramsci’s praxis philosophy, taken up by André Tosel, and Cornelius Castoriadis’ works on radical imaginary, this article analyses the debate about Marxism, during the year 1946 ... [more ▼]On the basis of Antonio Gramsci’s praxis philosophy, taken up by André Tosel, and Cornelius Castoriadis’ works on radical imaginary, this article analyses the debate about Marxism, during the year 1946, between two intellectual reviews: Les Temps Modernes and Critique. If the creation of those reviews is deeply related to a social context and an interdiscourse influenced by the political and ideological rise of extreme left – particularly the French Communist Party –, their project consists in a critical questioning of communist discourses, returning to Marx’s and Hegel’s texts. References to these philosophies induce different rhetorical and argumentative particularities that we intend to study in order to understand the complex relations between the rhetoric of a sociohistorical interdiscourse and his ideological substructure. [less ▲]Detailed reference viewed: 40 (7 ULiège) Post-embryonic development of sheepshead minnow Cyprinodon variegatus: a staging tool based on externally visible anatomical traitsSchnitzler, Joseph ; Dussenne, Mélanie ; Frederich, Bruno et alin Ichthyological Research (2017), 64The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse ... [more ▼]The sheepshead minnow Cyprinodon variegatus has become a favoured model for laboratory studies because of their small size, rapid development, and tolerance of laboratory conditions. Here, we analyse sheepshead minnow post-embryonic development with the goal of providing a generally useful method for staging fish after embryogenesis. Groups of three females and two males were placed in breeding chambers designed for this experiment. More than 100 eggs were collected and maintained in seawater. Embryos were selected under a dissection microscope and placed in incubation dishes (50 per dish) at 26 °C. On day six, embryos hatched and larvae were transferred to 1 L beakers. To define a simplified normalization table for sheepshead minnow development, we measured each fish for its standard length and examined the fish for four externally evident traits: pigmentation pattern, caudal fin morphology, anal fin morphology, and dorsal fin morphology. The four traits were chosen, because they are easily visualized with standard laboratory equipment such as the stereomicroscope and camera. We have provided criteria for staging sheepshead minnows in studies of post-embryonic development. Our data suggest that dorsal and anal fin morphology may serve as a useful phenotype for defining metamorphic climax stages throughout post-embryonic development in C. variegatus. The staging systems we propose should facilitate detailed anatomical and developmental analyses in relation to ecotoxicological studies on potential disruption of the thyroid axis by xenobiotics and endocrine-disrupting compounds. [less ▲]Detailed reference viewed: 40 (5 ULiège) Assessment of vitamin D status - a changing landscape.Herrmann, Markus; Farrell, Christopher-John L.; Pusceddu, Irene et alin Clinical Chemistry & Laboratory Medicine (2017)In recent years it has been shown that vitamin D deficiency is associated with an increased incidence as well as the progression of a broad range of diseases including osteoporosis, rickets ... [more ▼]In recent years it has been shown that vitamin D deficiency is associated with an increased incidence as well as the progression of a broad range of diseases including osteoporosis, rickets, cardiovascular disease, autoimmune disease, multiple sclerosis and cancer. Consequently, requests for the assessment of vitamin D status have increased dramatically. Despite significant progress in the analysis of vitamin D metabolites and an expansion of our pathophysiological knowledge of vitamin D, the assessment of vitamin D status remains a challenging and partially unresolved issue. Current guidelines from scientific bodies recommend the measurement of 25-hydroxy vitamin D (25-OHD) in blood as the preferred test. However, growing evidence indicates significant limitations of this test, including analytical aspects and interpretation of results. In addition, the relationships between 25-OHD and various clinical indices, such as bone mineral density and fracture risk, are rather weak and not consistent across races. Recent studies have systematically investigated new markers of vitamin D status including the vitamin D metabolite ratio (VMR) (ratio between 25-OHD and 24,25-dihydroxy vitamin D), bioavailable 25-OHD [25-OHD not bound to vitamin D binding protein (DBP)], and free 25-OHD [circulating 25-OHD bound to neither DBP nor albumin (ALB)]. These parameters may potentially change how we will assess vitamin D status in the future. Although these new biomarkers have expanded our knowledge about vitamin D metabolism, a range of unresolved issues regarding their measurement and the interpretation of results prevent their use in daily practice. It can be expected that some of these issues will be overcome in the near future so that they may be considered for routine use (at least in specialized centers). In addition, genetic studies have revealed several polymorphisms in key proteins of vitamin D metabolism that affect the circulating concentrations of vitamin D metabolites. The affected proteins include DBP, 7-dehydrocholesterol synthase and the vitamin D receptor (VDR). Here we aim to review existing knowledge regarding the biochemistry, physiology and measurement of vitamin D. We will also provide an overview of current and emerging biomarkers for the assessment of vitamin D status, with particular attention methodological aspects and their usefulness in clinical practice. [less ▲]Detailed reference viewed: 25 (0 ULiège) The Role of Companies in Smart City Initiatives: The Case of BelgiumAndre, Anne-Marie; Crutzen, Nathalie in Economia (2017)Detailed reference viewed: 72 (2 ULiège) Invited CommentaryLancellotti, Patrizio ; Nchimi Longang, Alain in Annals of Thoracic Surgery (2017), 103(1), 81-82Detailed reference viewed: 14 (1 ULiège) Habitat selection by marine larvae in changing chemical environmentsLecchini, David; Dixson, Danielle L.; Lecellier, Gael et alin Marine Pollution Bulletin (2017), 114The replenishment and persistence of marine species is contingent on dispersing larvae locating suitable habitat and surviving to a reproductive stage. Pelagic larvae rely on environmental cues to make ... [more ▼]The replenishment and persistence of marine species is contingent on dispersing larvae locating suitable habitat and surviving to a reproductive stage. Pelagic larvae rely on environmental cues to make behavioural decisions with chemical information being important for habitat selection at settlement. We explored the sensory world of crustaceans and fishes focusing on the impact anthropogenic alterations (ocean acidification, red soil, pesticide) have on conspecific chemical signals used by larvae for habitat selection. Crustacean (Stenopus hispidus) and fish (Chromis viridis) larvae recognized their conspecifics via chemical signals under control conditions. In the presence of acidified water, red soil or pesticide, the ability of larvae to chemically recognize conspecific cues was altered. Our study highlights that recruitment potential on coral reefs may decrease due to anthropogenic stressors. If so, populations of fishes and crustaceans will continue their rapid decline; larval recruitment will not replace and sustain the adult populations on degraded reefs. [less ▲]Detailed reference viewed: 16 (4 ULiège) Precision measurement of radioactivity in Gamma-rays spectrometry using two HPGe detectors (BEGe-6530 and GC0818-7600SL models) comparison techniques: Application to the soil measurement.Guembou Shouop, Cébastien Joel ; Samafou Penabei; NDONTCHUENG MOYO, Maurice et alin MethodsX (2017), 4(42-54), 2017To obtain high quality of results in gamma spectrometry, it is necessary to select the best HPGe detector for particular measurements, to calibrate energy and efficiency of gamma detector as accurate as ... [more ▼]To obtain high quality of results in gamma spectrometry, it is necessary to select the best HPGe detector for particular measurements, to calibrate energy and efficiency of gamma detector as accurate as possible. To achieve this aim, the convenient detector model and gamma source can be very useful. The purpose of this study was to evaluate the soil specific activity using two HPGe model (BEGe-6530 and GC0818-7600SL) by comparing the results of the two detectors and the technics used according to the detector type. The relative uncertainty activity concentration was calculated for 226Ra, 232Th and 40K. For broad energy germanium detector, BEGe-6530, the relative uncertainty concentration ranged from 2.85 to 3.09% with a mean of 2.99% for 226Ra, from 2.29 to 2.49% with a means of 2.36% for 232Th and from 3.47 to 22.37% with a mean of 12.52% for 40K. For GC0818-7600SL detector, it was ranged from 10.45 to 25.55% with a mean of 17.10% for 226Ra, from 2.54 to 3.56% with a means of 3.10% for 232Th and from 3.42 to 7.65% with a mean of 5.58% for 40K. The average report between GC0818-7600SL model and BEGe-6530 model was calculated and showed the mean value of 3.36. The main study was based on the following points: • Determination of The relative uncertainty activity concentration of 226Ra, 232Th and 40K • Determination of the relative uncertainty related to the radium equivalent activity to compare the performance of the two detection systems • Proved that the activity concentration determination in gamma spectrometry depended on the energy range emitted by a radionuclide. This study showed that the standard deviation measurement was less important to the result realized with BEGe-6530 HPGe model. Our findings were demonstrated that the results of the Broad Energy Germanium detector were more reliable. [less ▲]Detailed reference viewed: 22 (1 ULiège) Attention et simultanéité intellectuelle chez Descartes, Clauberg et SpinozaDubouclez, Olivier in Les études philosophiques (2017), 1Abstract. – is paper deals with a classical problem, can we think or apprehend many things at once ? as it was understood and solved by Descartes and its followers. e idea that we can apprehend di erent ... [more ▼]Abstract. – is paper deals with a classical problem, can we think or apprehend many things at once ? as it was understood and solved by Descartes and its followers. e idea that we can apprehend di erent ideas at once is central in Descartes’ theory of knowledge, especially in the Rules, and it relies on the claim that attention can be divided between two objects or ideas. Clauberg considers on the contrary that the imagination alone can graps things simultaneously and holds the living body as the true paradigm of simultaneous activity. Spinoza has a synthetic point of view : simultaneity within the body and the mind are expressions of the power of the individ- ual and of his develoment. Attention is no more a condition of intellectual simultaneity, as in Descartes, but is rather an obstacle which needs to be overcome to reach a richer and better understanding of reality. [less ▲]Detailed reference viewed: 31 (1 ULiège) Exploring Metacognition as Support for Learning TransferScharff, Lauren; Draeger, John; Verpoorten, Dominique et alin Teaching & Learning Inquiry: The ISSoTL Journal (2017), 5(1), The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning ... [more ▼]The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning transfer and staff do not always explicitly articulate this expectation, this article explores the idea that metacognition (intentional awareness and the use of that awareness) might enhance the development of learning transfer. Our exploratory study includes results from a survey of 74 staff and 118 students from five institutions in Australia, Belgium, UK, and USA. Our data indicate that many staff and a majority of students do not have a clear understanding of what learning transfer entails, and that there are many mismatches between staff and student perceptions, attitudes, and behaviors regarding learning transfer. This helps explain why learning transfer does not occur as often as it could. We found significant positive correlations between thinking about transfer and thinking about learning processes and the likelihood to use awareness of metacognition to guide practice. Our findings suggest a positive relationship between metacognition and learning transfer. Implications for scholarship of teaching and learning are discussed. [less ▲]Detailed reference viewed: 43 (1 ULiège) MICROPALEONTOLOGY OF THE LOWER MESOPROTEROZOIC ROPER GROUP, AUSTRALIA, AND IMPLICATIONS FOR EARLY EUKARYOTIC EVOLUTIONJavaux, Emmanuelle ; Knoll, Andrew H.in Journal of Paleontology (2017)Detailed reference viewed: 17 (1 ULiège) No copper required for germination of an endangered endemic species from the Katangan Copperbelt (Katanga, DR Congo): Diplolophium marthozianumBoisson, Sylvain ; Ortmans, William ; Maréchal, Justine et alin Tropical Ecology (2017), 58(1), 193-198Two hypotheses were tested with respect to the germination of Diplolophium marthozianum, an endemic plant species of the copper-cobalt outcrops in Katanga, Democratic Republic of Congo: (1) germination of ... [more ▼]Two hypotheses were tested with respect to the germination of Diplolophium marthozianum, an endemic plant species of the copper-cobalt outcrops in Katanga, Democratic Republic of Congo: (1) germination of copper-endemics is limited by fungal infection in the absence of pathogen control and (2) the germination success of this copper-endemic species is copper-dependent. Seed lots of twenty seeds were weighed, soaked in different disinfection treatments and then placed in a germination medium containing four distinct copper concentrations for 30 days. Seed viability was measured at the beginning and at the end of the experiment by a cut test. Final germination percentage (15.2 ± 8.2 %) and seed viability (24.2 ± 10.3 %) were not affected by copper concentration or disinfection treatments. D. marthozianum is able to germinate in a substrate without added copper, despite pervasive fungal infection. However, seed mass had a significant positive effect on seed germination suggesting that selecting the largest seeds may ensure the highest germination success in ex situ conservation programs. [less ▲]Detailed reference viewed: 34 (4 ULiège) Etude rétrospective du bilan thyroïdien: définition de valeurs de référence pédiatriquesLADANG, Aurélie ; VRANKEN, Laura ; LUYCKX, Françoise et alin Revue Médicale de Liège (2017)Defining reference range is an essential tool for diagnostic. Age and sexe influences on thyroid hormone levels have been already discussed. In this study, we are defining a new pediatric reference range ... [more ▼]Defining reference range is an essential tool for diagnostic. Age and sexe influences on thyroid hormone levels have been already discussed. In this study, we are defining a new pediatric reference range for TSH, FT3 and FT4 for Cobas C6000 analyzer. To do so, we have taken in account 0 to 18 year old outclinic patients. During the first year of life, thyroid hormone levels change dramatically before getting stabilized around 3 years old. We also compared our results to those obtained in a Canadian large-scale prospective study (the CALIPER initiative). [less ▲]Detailed reference viewed: 79 (1 ULiège) Bioclimatism in Architecture : an evolutionary perspectiveNguyen, Anh Tuan; Reiter, Sigrid in International Journal of Design and Nature and Ecodynamics (2017), 12(1), 16-29Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that ... [more ▼]Fundamentals of vernacular architecture have been used in bioclimatic architecture which has gradually become the inspiration of various movements in contemporary architecture. The study points out that the development of bioclimatism in architecture has followed the pattern of a natural evolutionary process in which “natural selection” is likely motivated by several factors, including resources and environment problems, and driven by different mechanisms including novel building design concepts and methods, new standards and codes, discoveries in building science and construction costs. This study is an effort aimed to clarify the evolution process of the bioclimatic approach in architecture over time and its influences on contemporary movements in architecture. The paper shows also that the evolutionary theory generated new scientific tools able to improve building design thanks to simulation-based optimization methods applied to building performances. Finally, this study investigates new motivations in the era of climate change whose effects are expected to introduce more challenges as well as more trends towards a sustainable built environment through the new concept of Eco-adaptive architecture. [less ▲]Detailed reference viewed: 88 (4 ULiège) The design and study of new Li-ion full cells of LiCo2/3Ni1/6Mn1/6O2 positive electrode paired with MnSn2 and Li4Ti5O12 negative electrodesMahmoud, Abdelfattah ; Saadoune, Ismael; Lippens, Pierre-Emmanuel et alin Solid State Ionics (2017), 300We report evidence for the electrochemical performances of two Li-ion full cells, built up by the combination of LiCo2/3Ni1/6Mn1/6O2 cathode material with MnSn2 intermetallic and Li4Ti5O12 spinel as the ... [more ▼]We report evidence for the electrochemical performances of two Li-ion full cells, built up by the combination of LiCo2/3Ni1/6Mn1/6O2 cathode material with MnSn2 intermetallic and Li4Ti5O12 spinel as the anode materials, respectively. MnSn2 and Li4Ti5O12 electrode materials illustrate different working voltage versus the redox couple Li+/Li0 and different reactionmechanisms during lithiuminsertion/deinsertion cycles. The structure,morphological characteristics and the electrochemical properties of the studied materialswere investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and electrochemical techniques. The two full-cell configurations showed different electrochemical behaviors. The MnSn2//LiCo2/3Ni1/6Mn1/6O2 configuration exhibits high working voltage (~3.5 V) and specific capacity (~200 mAh/gcathode) but suffers from high irreversible capacity loss during the first cycles and capacity fading during cycling. The Li4Ti5O12//LiCo2/3Ni1/6Mn1/6O2 cell demonstrated excellent cycling properties at different C-rates with 100% capacity retention after 150 cycles at 1 C. Although the working voltage (~2.2 V) and the specific capacity (~140 mAh/gcathode) are lower than those of the MnSn2//LiCo2/3Ni1/6Mn1/6O2 configuration, the other measured electrochemical properties suggest that the Li4Ti5O12//LiCo2/3Ni1/6Mn1/6O2 full cell is a potential candidate for battery application due to its excellent cycling performance and improved safety. [less ▲]Detailed reference viewed: 21 (2 ULiège) Sofosbuvir in Combination with Simeprevir +/- Ribavirin in Genotype 4 Hepatitis C Patients with Advanced Fibrosis or Cirrhosis: A Real-World Experience from BelgiumDegré, D; Sersté, T; Lasser, L et alin PLoS ONE (2017), 12(1), 0170933Detailed reference viewed: 31 (2 ULiège) Spatial variation in the accumulation of POPs and mercury in bottlenose dolphins of the Lower Florida Keys and the coastal Everglades (South Florida)Damseaux, France ; Kiszka, J.; Heithaus, M.R. et alin Environmental Pollution (2017), 220The bottlenose dolphin (Tursiops truncatus) is an upper trophic level predator and the most common cetacean species found in nearshore waters of southern Florida, including the Lower Florida Keys (LFK ... [more ▼]The bottlenose dolphin (Tursiops truncatus) is an upper trophic level predator and the most common cetacean species found in nearshore waters of southern Florida, including the Lower Florida Keys (LFK) and the Florida Coastal Everglades (FCE). The objective of this study was to assess contamination levels of total mercury (T-Hg) in skin and persistent organic pollutants (PCBs, PBDEs, DDXs, HCHs, HCB, Σ PCDD/Fs and Σ DL-PCBs) in blubber samples of bottlenose dolphins from LFK (n = 27) and FCE (n = 24). PCBs were the major class of compounds found in bottlenose dolphin blubber and were higher in individuals from LFK (Σ 6 PCBs LFK males: 13421 ± 7730 ng.g-1 lipids, Σ 6 PCBs LFK females: 9683 ± 19007 ng.g-1 lipids) than from FCE (Σ 6 PCBs FCE males: 5638 ng.g-1 ± 3627 lipids, Σ 6 PCBs FCE females: 1427 ± 908 ng.g-1 lipids). These levels were lower than previously published data from the southeastern USA. The Σ DL-PCBs were the most prevalent pollutants of dioxin and dioxin like compounds (Σ DL-PCBs LFK: 739 ng.g-1 lipids, Σ DL-PCBs FCE: 183 ng.g-1 lipids) since PCDD/F concentrations were low for both locations (mean 0.1 ng.g-1 lipids for LFK and FCE dolphins). The toxicity equivalences of PCDD/Fs and DL-PCBs expressed as TEQ in LFK and FCE dolphins is mainly expressed by DL-PCBs (81% LFK - 65% FCE). T-Hg concentrations in skin were significantly higher in FCE (FCE median 9314 ng.g-1 dw) compared to LFK dolphins (LFK median 2941 ng.g-1 dw). These bottlenose dolphins concentrations are the highest recorded in the southeastern USA, and may be explained, at least partially, by the biogeochemistry of the Everglades and mangrove sedimentary habitats that create favourable conditions for the retention of mercury and make it available at high concentrations for aquatic predators. [less ▲]Detailed reference viewed: 77 (17 ULiège) Goat breeding in the rural district of Chemini (Algeria)Moula, Nassim ; Ait Kaki, Asma; Touazi, Leghel et alin Nature & Technology (2017), n° 16/JanvierThe Kabyle goat breed represents 10.52% of the total Algerian market (3.8 million heads). A survey of 69 farmers has been carried out in order to characterize it and its breeding in the District of ... [more ▼]The Kabyle goat breed represents 10.52% of the total Algerian market (3.8 million heads). A survey of 69 farmers has been carried out in order to characterize it and its breeding in the District of Chemini. The questions focused on household agricultural activities, including breeding of goats, cattle, sheep, rabbits, chicken, turkeys, honeybees and the production of olive oil and figs. The goat morpho-biometric characterization was based on 18 corporal measurements. The Hierarchical Cluster Analysis (HCA) of the farm structures defined four groups of farms, variance between groups accounting for 55.7% of total variability. The average number of goats in groups 1 to 4 was 7.2±2.8, 11.1±3.5, 22.3±1.4 and 3.4±1.0, respectively. Group 3 (n=6), showed the greatest number; it consists of older farmers (67 years old or over) not practicing arboriculture. They also have the largest numbers of sheep (48.67), rabbits (50.83), chicken (48.33) and turkeys (42). Group 4 (n=9), with the lowest number of goats, was the group of young farmers (39 years old or less), more dedicated to cattle breeding (~52 heads) and the production of olive oil (~207 trees) and figs (~47 trees). The 18 morpho-biometric variables were significantly higher in males than in females (p<0.05). The Kabyle goat is small (Height at withers: male: 68.23±0.97cm and female: 65.41±0.55cm) with long hair (male: 12.24±0.51cm, and female: 9.51±0.29cm). Its ears are drooping, its convex profile has a slightly pronounced nasal split and its dress color ranges from dark brown to black. This adapted genetic resource should be key in the development of a local production, based on a strong commitment of farmers inside a breed association, for the production of specimens corresponding to a standard, to be determined collectively. [less ▲]Detailed reference viewed: 106 (22 ULiège) Characteristics of EoL Printed Wiring Boards processed by ElectroDynamic FragmentationMartino, Rémi ; Iseli, Cedric; Gaydardzhiev, Stoyan et alin Chemie Ingenieur Technik (2017), 89(1-2), 1-10The ElectroDynamic Fragmentation (EDF) is an innovative technique which enables selective fragmentation of material. Its inherent selective breakage principles enable liberation while avoiding fine ... [more ▼]The ElectroDynamic Fragmentation (EDF) is an innovative technique which enables selective fragmentation of material. Its inherent selective breakage principles enable liberation while avoiding fine grinding. In this study, the specific effects of the EDF on End-of-Life Printed Wiring Boards have been assessed. A novel methodology for their EDF processing has been developed and compared with hammer mill shredding. Various energy inputs and treatment stages have resulted in fragmentation degrees ranging from removal of components to structure delamination and subsequent size reduction. [less ▲]Detailed reference viewed: 33 (5 ULiège) PESTO SAUCE TYPE PRODUCTS: INFLUENCE OF BEESWAX AND STORAGE CONDITIONS ON RHEOLOGY AND COLLOIDAL STABILITYBouacida, Saoussen; Muresan, Vlad; Essaidi, Ismahen et alin Journal of Microbiology, Biotechnology and Food Sciences (2017), 6(3), 911-920One of the major problems for pesto sauce type products is the tendency of oil to cream, causing their alteration and decreasing consumer’s acceptability. In this study, colloidal and oxidative stability ... [more ▼]One of the major problems for pesto sauce type products is the tendency of oil to cream, causing their alteration and decreasing consumer’s acceptability. In this study, colloidal and oxidative stability of pesto samples with (0.5-1.2%) of beeswax was evaluated during storage at 4, 20 and 40°C. The rheological behavior and color analysis was evaluated at the same temperatures. Sensory evaluation by using a hedonic test was also perfomed. Increasing the samples beeswax content increased the pesto colloidal stability. The samples with 0.8-1.2% have the highest stability and overall performed well on sensory analysis. The peroxide values of samples increased significantly (p<0.05) with storage time and temperature, as well as the p-anisidine values. During the storage at 40°C, peroxide values of samples without wax and with 1,2% wax increased from 11.75 to 33.81 and 32.72 meq O2/kg, respectively. In the same condition, p-Anisidine values increased from 4.51 to 10.71 and 9.94, respectively. For these same samples stored 793 h, peroxide values increased from 13.33 to 33.81 and to 32.72 meq O2/kg, when the temperature increased from 4 to 40°C. The same observation was made for p-anisidine values, which increased from 8.40 to 10.71 and 9.94. As expected, the pesto samples showed the best oxidative stability at low temperature. It was shown that beeswax content, temperature and time of storage are important parameters for controlling pesto rheology, colloidal and oxidative stability. In fact, the pseudo plasticity of samples increases with increasing beeswax added and with decreasing the temperature. The colloidal and oxidative stability of samples decreased as the storage time and temperature increased. [less ▲]Detailed reference viewed: 21 (0 ULiège) L'attention chez Descartes. Aspect mental et aspect physiologiqueHatfield, Gary; Dubouclez, Olivier in Les études philosophiques (2017), (1), 7-25Résumé. – Bien qu’il n’ait pas donné une analyse approfondie du concept d’attention, Descartes invoque fréquemment l’attention. Il a observé et décrit une diversité de phénomènes attentionnels et ... [more ▼]Résumé. – Bien qu’il n’ait pas donné une analyse approfondie du concept d’attention, Descartes invoque fréquemment l’attention. Il a observé et décrit une diversité de phénomènes attentionnels et les a replacés dans un cadre explicatif qui prend en compte aussi bien leurs aspects mentaux que physiologiques. Il a mis en relation la focalisation de l’attention et les actes de la volonté. Dans le cas de l’attention aux perceptions sensibles ou aux actes de l’imagination, il a décrit en détails les processus physiologiques qui captent l’attention, la maintiennent ou la détournent. Ces processus physiologiques montrent bien que la personne cartésienne constitue une unité fonctionnelle formée d’une âme et d’un corps. [less ▲]Detailed reference viewed: 15 (0 ULiège) La cigarette électronique : état des connaissances à propos des aspects toxicologiquesDEVILLE, Marine ; CHARLIER, Corinne in Revue Médicale de Liège (2017), 72(1), 20-24La cigarette électronique, aussi appelée e-cigarette, est présentée comme une alternative au tabagisme qui serait moins nocive pour la santé. Son fonctionnement repose sur la conversion d’un liquide en ... [more ▼]La cigarette électronique, aussi appelée e-cigarette, est présentée comme une alternative au tabagisme qui serait moins nocive pour la santé. Son fonctionnement repose sur la conversion d’un liquide en vapeur, sous l’action de la chaleur générée par un filament présent dans un atomiseur. Le liquide est majoritairement composé de propylène glycol et/ou de glycérine, utilisé(s) pour produire l’effet de fumée, auxquels s’ajoutent des arômes et, éventuellement, de la nicotine. A l’exception de cette dernière, potentiellement létale lorsqu’elle est ingérée à haute dose, ces constituants sont généralement reconnus comme sans danger. Cependant, les conséquences d’une inhalation chronique de propylène glycol sont méconnues. Avantageusement, les composés qui rendent la cigarette traditionnelle particulièrement nuisible – nitrosamines, formaldéhyde, métaux, monoxyde de carbone,… - sont soit absents, soit présents en faible quantité dans la vapeur d’une e-cigarette, sans comparaison avec les taux mesurés dans la fumée d’une cigarette conventionnelle. Il en résulte un profil de toxicité rassurant pour la e-cigarette, bien que son efficacité dans le sevrage tabagique reste à démontrer. [less ▲]Detailed reference viewed: 160 (9 ULiège) Morphology of the filtration apparatus of three planktivorous fishes and relation with ingested anthropogenic particlesCollard, France ; Gilbert, Bernard ; Eppe, Gauthier et alin Marine Pollution Bulletin (2017)Anthropogenic particles (APs), including microplastics, are ingested by a wide variety of marine organisms. Exposure of Clupeiformes (e.g. herrings, anchovies, sardines) is poorly studied despite their ... [more ▼]Anthropogenic particles (APs), including microplastics, are ingested by a wide variety of marine organisms. Exposure of Clupeiformes (e.g. herrings, anchovies, sardines) is poorly studied despite their economic and ecological importance. This study aims to describe the morphology of the filtration apparatus of three wild-caught Clupeiformes (Sardina pilchardus, Clupea harengus and Engraulis encrasicolus) and to relate the results to ingested APs. Consequently, the species with the more efficient filtration apparatus will be more likely to ingest APs. We hypothesized that sardines were the most exposed species. The filtration area and particle retention threshold were determined in the three species, with sardines displaying the highest filtration area and the closest gill rakers. Sardines ingested more fibers and smaller fragments, confirming that it is the most efficient filtering species. These two results lead to the conclusion that, among the three studied, the sardine is the species most exposed to APs. [less ▲]Detailed reference viewed: 192 (7 ULiège) European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 2: TreatmentWERNER R.N.; NIKKELS, Arjen ; MARINOVIC B. et alin Journal of the European Academy of Dermatology & Venereology (2017)Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim ... [more ▼]Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localizations. This interdisciplinary guideline aims at an improvement of the outcomes of the acute HZ management concerning disease duration, acute pain and quality of life of the affected patients and at a reduction in the incidence of postherpetic neuralgia (PHN) and other complications. The guideline development followed a structured and pre-defined process, considering the quality criteria for guidelines development as suggested by the AGREE II instrument. The steering group was responsible for the planning and the organization of the guideline development process (Division of Evidence-Based Medicine, dEBM). The expert panel was nominated by virtue of clinical expertise and/or scientific experience and included experts from the fields of dermatology, virology/infectiology, ophthalmology, otolaryngology, neurology and anaesthesiology. Recommendations for clinical practice were formally consented during the consensus conference, explicitly considering different relevant aspects. The guideline was approved by the commissioning societies after an extensive internal and external review process. In this second part of the guideline, therapeutic interventions have been evaluated. The expert panel formally consented recommendations for the treatment of patients with HZ (antiviral medication, pain management, local therapy), considering various clinical situations. Users of the guideline must carefully check whether the recommendations are appropriate for the context of intended application. In the setting of an international guideline, it is generally important to consider different national approaches and legal circumstances with regard to the regulatory approval, availability and reimbursement of diagnostic and therapeutic interventions. [less ▲]Detailed reference viewed: 22 (0 ULiège) Re-entrant inclusions in cellular solids: From defects to reinforcementsZorzetto, Laura ; Ruffoni, Davide in Composite Structures (2017), 176Abstract A contrast in Poisson ratio is a possible strategy to enhance the stiffness of composite structures. In solid materials Poisson ratio is hardly tailorable unless cellular architectures are ... [more ▼]Abstract A contrast in Poisson ratio is a possible strategy to enhance the stiffness of composite structures. In solid materials Poisson ratio is hardly tailorable unless cellular architectures are considered. Here, we first investigated the effect of a single re-entrant inclusion acting as a defect into a regular (non-re-entrant) honeycomb lattice. Building on this, we generated regular patterns of re-entrant inclusions into a regular hexagonal cellular matrix and we characterized the apparent stiffness and Poisson ratio of the obtained structures. We also explored the role of the intrinsic material properties of the inclusion as well as of its closest environment on the interplay between the deformations of different phases in the lattice. Our main finding is that a small fraction of re-entrant inclusions (around 12%) is sufficient to generate a substantial augmentation in stiffness (300%) at constant overall relative density and without inducing strong anisotropy. Eventually, we fabricated by 3D polyjet printing bi-material composite architectures to demonstrate the superior mechanical behavior obtained exploiting the Poisson effect. [less ▲]Detailed reference viewed: 59 (7 ULiège) Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levelsVignisse, Julie ; Sambon, Margaux ; Gorlova, Anna et alin Molecular and Cellular Neuroscience (2017), 82Thiamine is essential for normal brain function and its deficiency causes metabolic impairment, specific lesions, oxidative damage and reduced adult hippocampal neurogenesis (AHN). Thiamine precursors ... [more ▼]Thiamine is essential for normal brain function and its deficiency causes metabolic impairment, specific lesions, oxidative damage and reduced adult hippocampal neurogenesis (AHN). Thiamine precursors with increased bioavailability, especially benfotiamine, exert neuroprotective effects not only for thiamine deficiency (TD), but also in mouse models of neurodegeneration. As it is known that AHN is impaired by stress in rodents, we exposed C57BL6/J mice to predator stress for 5 consecutive nights and studied the proliferation (number of Ki67-positive cells) and survival (number of BrdU-positive cells) of newborn immature neurons in the subgranular zone of the dentate gyrus. In stressed mice, the number of Ki67- and BrdU-positive cells was reduced compared to non-stressed animals. This reduction was prevented when the mice were treated (200 mg/kg/day in drinking water for 20 days) with thiamine or benfotiamine, that were recently found to prevent stress-induced behavioral changes and glycogen synthase kinase-3β (GSK-3β) upregulation in the CNS. Moreover, we show that thiamine and benfotiamine counteract stress-induced bodyweight loss and suppress stress-induced anxiety-like behavior. Both treatments induced a modest increase in the brain content of free thiamine while the level of thiamine diphosphate (ThDP) remained unchanged, suggesting that the beneficial effects observed are not linked to the role of this coenzyme in energy metabolism. Predator stress increased hippocampal protein carbonylation, an indicator of oxidative stress. This effect was antagonized by both thiamine and benfotiamine. Moreover, using cultured mouse neuroblastoma cells, we show that in particular benfotiamine protects against paraquat-induced oxidative stress. We therefore hypothesize that thiamine compounds may act by boosting anti-oxidant cellular defenses, by a mechanism that still remains to be unveiled. Our study demonstrates, for the first time, that thiamine and benfotiamine prevent stress-induced inhibition of hippocampal neurogenesis and accompanying physiological changes. The present data suggest that thiamine precursors with high bioavailability might be useful as a complementary therapy in several neuropsychiatric disorders. [less ▲]Detailed reference viewed: 34 (5 ULiège) L’ÉVALUATION DES POLITIQUES PUBLIQUES DANS LE CHAMP DE LA COOPÉRATION AU DÉVELOPPEMENT BELGE : LE CAS DU SERVICE DE L’ÉVALUATION SPÉCIALEContor, Justine in Pyramides : Revue du Laboratoire d'Etudes et de Recherches en Administration Publique (2017)Cette contribution s’intéresse à l'évolution institutionnelle de l'évaluation au sein de la coopération belge au développement et plus spécifiquement à notre cas d’étude : le Service de l’Evaluation ... [more ▼]Cette contribution s’intéresse à l'évolution institutionnelle de l'évaluation au sein de la coopération belge au développement et plus spécifiquement à notre cas d’étude : le Service de l’Evaluation Spéciale de la coopération belge au développement (SES). Nous présenterons dans ce document les raisons de la création de ce service au début des années 2000. En effet, le SES, avec d’autres acteurs, est le résultat d’une grande réforme de la coopération issue d’une lourde crise. Nous reviendrons sur son mandat, sur ses spécificités organisationnelles (ressources financières et humaines) ainsi que son cadre de référence normatif. La question de la culture évaluative sera questionnée, ainsi que son lien avec l’émergence du New Public Management dans la politique de coopération au développement. Enfin, nous questionnerons la légitimité d’une structure telle que le SES au regard d’un cadrage théorique mixte (Scott, 1995 ; Suchmann, 1995) et de la théorie des parties prenantes. [less ▲]Detailed reference viewed: 53 (4 ULiège) Retos actuales en la caracterización de los flujos agua-aire en grandes obras hidráulicasValero Huerta, Daniel in REVISTA HIDROLATINOAMERICANA (2017), 1Present literature on air-water flows is briefly reviewed, including articles of the main five international Journals published along the last four years. Main advances in the most fruitful topics related ... [more ▼]Present literature on air-water flows is briefly reviewed, including articles of the main five international Journals published along the last four years. Main advances in the most fruitful topics related to air entrainment are discussed. Main areas of interest are: stepped spillways, bubbles in pipe flows, numerical modelling and instrumentation. [less ▲]Detailed reference viewed: 33 (3 ULiège) Occurrence of Clinical Bone Fracture Following a Prolonged Stay in Intensive Care Unit: A Retrospective Controlled StudyROUSSEAU, Anne-Françoise ; CAVALIER, Etienne ; Reginster, Jean-Yves et alin Calcified Tissue International (2017), (Online), Clinical consequences of critical illness and critical care (CC) on bone health remain largely unexplored. This retrospective study aimed to assess the number of new bone fractures (BF) following a ... [more ▼]Clinical consequences of critical illness and critical care (CC) on bone health remain largely unexplored. This retrospective study aimed to assess the number of new bone fractures (BF) following a prolonged length of stay (LOS) in intensive care unit (ICU). Adults admitted in our tertiary ICU during 2013 with a stay [7 days were included (CC group). Patients who died in ICU or lost to follow-up were excluded. For each CC patient still alive after 2 years of follow-up, 2 control patients, scheduled for surgery during 2013, were recruited and matched for gender and age. Basal fracture risk before admission was calculated using FRAX tool. General practitioners were phoned to check out new bone fracture (BF) during 2 years after admission. Of the 457 enrolled CC patients, 207 did not meet inclusion criteria and 72 died during FU (median age 72 [65–77] years). New BF occurred in 9 of the 178 patients still alive at the end of FU (5%). Median age of these patients was 64 [53–73] years. Fractured patients did not differ from non-fractured ones based on demographic and clinical characteristics, excepting for FRAX risks that were higher in fractured patients. In the control group, 327 patients were analyzed. Their rate of BF was 3.4% without statistical significance compared to the CC group. FRAX risks were similar in both groups. The risk of new BF in CC group, expressed as an odds ratio, was 50% higher than in the control group without achieving statistical significance (odds ratio 1.53; 95% confidence interval 0.62–3.77; p = 0.35). When comparing ICU survivors to patients who underwent uncomplicated surgery in the present preliminary study included limited cohorts, the fracture risk in the 2 years following prolonged ICU stay was not statistically higher. However, CC fractured patients had higher FRAX risks than non-fractured patients. Such screening could help to target prevention and appropriate treatment strategies. [less ▲]Detailed reference viewed: 31 (6 ULiège) Metamemory Following Childhood Brain Injury: A Consequence of Executive ImpairmentGeurten, Marie ; Chevignard, Mathilde; Kerrouche, Bernadette et alin Child Neuropsychology : A Journal on Normal & Abnormal Development in Childhood & Adolescence (2017), 23(1), 67-82In this study, we investigated the influence of children’s level of executive functioning on two types of metamemory knowledge following a traumatic brain injury (TBI). For this purpose, 22 children (aged ... [more ▼]In this study, we investigated the influence of children’s level of executive functioning on two types of metamemory knowledge following a traumatic brain injury (TBI). For this purpose, 22 children (aged 7 to 14 years) who had sustained a moderate to severe TBI and 44 typically developing children were recruited. Children with TBI were divided into two groups according to the severity of their executive impairment. Injury severity was determined by the Glasgow Coma Scale (GCS) score on admission or by the duration of unconsciousness. All children were then tested on both their knowledge of general memory functioning and their level of memory self-awareness, respectively assessed using total number of correct responses on an adapted version of Kreutzer et al.’s metamemory interview and a self-other discrepancy score on a questionnaire evaluating everyday memory abilities. Data analyses revealed that participants with TBI who suffered impaired executive functions demonstrated less general metamemory knowledge, and underestimated the frequency of their memory problems, compared with children with TBI who had preserved executive functions and with control participants. Considering the well-established effect of metamemory knowledge on people’s spontaneous implementation of strategies, the interest and the importance of these findings on both theoretical and clinical grounds are discussed. [less ▲]Detailed reference viewed: 23 (3 ULiège) Electrically charged droplets in microgravitybrandenbourger, martin; Caps, Hervé ; vitry, youen et alin Microgravity Science and Technology (2017)Detailed reference viewed: 18 (0 ULiège) Cenozoic vegetation gradients in the mid- and higher latitudes of central Eurasia and climatic implicationsPopova, S.; Utescher, T.; Gromyko, D. V. et alin Palaeogeography, Palaeoclimatology, Palaeoecology (2017), 467Detailed reference viewed: 10 (0 ULiège) Experimental investigation of four volumetric expandersDumont, Olivier ; Dickes, Rémi ; Lemort, Vincent in Energy Procedia (2017)Detailed reference viewed: 466 (19 ULiège) Unrelated donor haemopoietic stem-cell transplantation: ATG or not?Baron, Frédéric in The Lancet. Haematology (2017), 4(6), 252-253Detailed reference viewed: 43 (1 ULiège) Agro-physiological and biochemical responses of faba bean (Vicia faba L. var. 'minor') genotypes to water deficit stressAbid, Ghassen; Hessini, Kamel; Aouida, Marwa et alin Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment (2017), 21(2), Drought is one of the major abiotic factors affecting growth and productivity of plants by imposing certain morphological, physiological and biochemical changes at different growth stages. The objective ... [more ▼]Drought is one of the major abiotic factors affecting growth and productivity of plants by imposing certain morphological, physiological and biochemical changes at different growth stages. The objective of this work is to study key morphological, physiological and biochemical response of faba bean (Vicia faba L. var. 'minor') to soil water deficit stress and to assess the contribution of genetic factors in improving faba bean tolerance to water deficit. Plant of 11 faba bean cultivars were grown in the greenhouse and subjected to three levels of water deficit (90, 50 and 30% of field capacity (FC)) in a simple randomized design for 20 days. Water deficit effects on plant growth, relative water content (RWC), gaz exchange, chlorophyll a (Chla) and Chlorophyll b (Chlb) content, osmoprotectant accumulations (such as proline and soluble sugars), antioxydant enzyme activities and grain yield were determined. Soil water deficit stress reduced growth and affected physiological parameters, especially antioxidant enzyme activities. Water deficit also increased proline, soluble sugars and protein contents. The studied cultivars significantly differed in their responses to water deficit stress. Photosynthetic parameters were less affected in the 'Hara' cultivar. Furthermore, this cultivar produced the highest value of grain yield at 30% FC, and showed higher antioxidant enzyme activities (CAT, GPX and APX), osmoprotectant accumulations, Chlb and RWC. The 'Hara' cultivar was found to be more tolerant to water deficit stress than the other cultivars. Our methodology can be used for assessing the response of faba bean genetic resources to soil water deficit. The identified tolerant cultivar can be utilized as a source for water stress tolerance in faba bean breeding programs aimed at improving drought tolerance. [less ▲]Detailed reference viewed: 76 (1 ULiège) Formaliser le trope : De la subjectivité linguistique à la subjectivité épilinguistiqueMathy, Adrien in Signata. Annales des Sémiotiques = Annals of Semiotics (2017)Detailed reference viewed: 46 (11 ULiège) Trace element concentrations in the apex predator swordfish (Xiphias gladius) from a Mediterranean fishery and risk assessment for consumersGobert, Sylvie ; Pasqualini, Vanina; Dijoux, Jessica et alin Marine Pollution Bulletin (2017), 120Swordfish (Xiphias gladius L., 1758) is an apex predator, highly migratory meso-pelagic fish widely distributed in the Atlantic Ocean and Mediterranean. As top predators, this fish may be the end ... [more ▼]Swordfish (Xiphias gladius L., 1758) is an apex predator, highly migratory meso-pelagic fish widely distributed in the Atlantic Ocean and Mediterranean. As top predators, this fish may be the end reservoir of the bioaccumulation of trace elements in a food chain because they occupy higher trophic levels and are an important food source, causing them to be potentially hazardous to consume. This study aims to investigate the concentration of 18 trace elements of Swordfish, caught in the Mediterranean Sea and to discuss human exposure risks. The mean element levels in the fish muscles were clearly below the maximum allowable concentrations established by International food safety regulations. The data suggested that the risk is minor and acceptable for human health. The findings of this study amplify the scarce database on contaminants available, especially new data on “emerging elements”, for this species from the Mediterranean Sea. [less ▲]Detailed reference viewed: 26 (1 ULiège) Dermatophytes and Dermatophytoses: A Thematic Overview of State of the Art, and the Directions for Future Research and DevelopmentsBouchara, JP; Mignon, Bernard ; Chaturvedi, Vin Mycopathologia (2017), 182(1), 1-4Detailed reference viewed: 31 (4 ULiège) Uncertain altruism and the provision of long term careCremer, Helmuth; Gahvari, Firouz; Pestieau, Pierre in Journal of Public Economics (2017), 151Detailed reference viewed: 14 (0 ULiège) Relevant Animal Models in Dermatophyte ResearchCambier, Ludivine ; Heinen, Marie-Pierre ; Mignon, Bernard in Mycopathologia (2017), 182(1), 229-240Detailed reference viewed: 30 (3 ULiège) Comparative Genomic Analysis Reveals Ecological Differentiation in the Genus Carnobacterium.Iskandar, Christelle F.; Borges, Frederic; Taminiau, Bernard et alin Frontiers in Microbiology (2017), 8Lactic acid bacteria (LAB) differ in their ability to colonize food and animal-associated habitats: while some species are specialized and colonize a limited number of habitats, other are generalist and ... [more ▼]Lactic acid bacteria (LAB) differ in their ability to colonize food and animal-associated habitats: while some species are specialized and colonize a limited number of habitats, other are generalist and are able to colonize multiple animal-linked habitats. In the current study, Carnobacterium was used as a model genus to elucidate the genetic basis of these colonization differences. Analyses of 16S rRNA gene meta-barcoding data showed that C. maltaromaticum followed by C. divergens are the most prevalent species in foods derived from animals (meat, fish, dairy products), and in the gut. According to phylogenetic analyses, these two animal-adapted species belong to one of two deeply branched lineages. The second lineage contains species isolated from habitats where contact with animal is rare. Genome analyses revealed that members of the animal-adapted lineage harbor a larger secretome than members of the other lineage. The predicted cell-surface proteome is highly diversified in C. maltaromaticum and C. divergens with genes involved in adaptation to the animal milieu such as those encoding biopolymer hydrolytic enzymes, a heme uptake system, and biopolymer-binding adhesins. These species also exhibit genes for gut adaptation and respiration. In contrast, Carnobacterium species belonging to the second lineage encode a poorly diversified cell-surface proteome, lack genes for gut adaptation and are unable to respire. These results shed light on the important genomics traits required for adaptation to animal-linked habitats in generalist Carnobacterium. [less ▲]Detailed reference viewed: 19 (1 ULiège) Pest and mould infestation of smoked shrimp and preventive measures for storage in cottage industryKpoclou; Anihouvi; Azokpota et alin Indian Journal of Traditional Knowledge (2017), 16Detailed reference viewed: 23 (3 ULiège) Two-Parameter Kinematic Approach for Shear Strength of Deep Concrete Beams with Internal FRP ReinforcementMihaylov, Boyan in Journal of Composites for Construction (2017), DOI: 10.1061/(ASCE)CC.1943-5614 .0000747Tests of deep concrete beams with internal fiber-reinforced polymer (FRP) reinforcement have shown that such members can exhibit lower shear strength than members with conventional steel reinforcement. To ... [more ▼]Tests of deep concrete beams with internal fiber-reinforced polymer (FRP) reinforcement have shown that such members can exhibit lower shear strength than members with conventional steel reinforcement. To model this effect, the current paper proposes an approach based on a two-parameter kinematic theory (2PKT) for conventional deep beams. The 2PKT is built on a kinematic model with two degrees of freedom that describes the deformation patterns of cracked beams. Using this theory shows that large strains in FRP longitudinal reinforcement result in reduced shear resistance of the critical loading zones (CLZ) of deep beams. The original 2PKT is therefore modified by introducing a reduction factor for the shear carried by the CLZ. The extended 2PKT approach is then applied to a database of 39 tests of FRP-reinforced deep beams from the literature, resulting in an average shear strength experimental-to-predicted ratio of 1.06 and a coefficient of variation of 18.3%. The results show that the 2PKT adequately captures the effects of the stiffness of the reinforcement, section depth, concrete strength, and shear-span-to-depth ratio on the shear strength of FRP-reinforced deep beams. [less ▲]Detailed reference viewed: 30 (7 ULiège) Magnetocapillary self-assemblies: locomotion and micromanipulation along a liquid interfaceGrosjean, Galien ; Hubert, Maxime ; Vandewalle, Nicolas in Advances in Colloid and Interface Science (2017)Review article on magnetocapillary self-assemblies, and in particular microswimmers, which includes new results concerning the manipulation of small objects and the mixing fluid at low Reynolds number.Detailed reference viewed: 18 (0 ULiège) The proteolytic system of pineapple stems revisited: Purification and characterization of multiple catalytically active forms.Matagne, André ; Bolle, Laetitia; El Mahyaoui, Rachida et alin Phytochemistry (2017), (138), 29-51Crude pineapple proteases extract (aka stem bromelain; EC 3.4.22.4) is an important proteolytic mixture that contains enzymes belonging to the cysteine proteases of the papain family. Numerous studies ... [more ▼]Crude pineapple proteases extract (aka stem bromelain; EC 3.4.22.4) is an important proteolytic mixture that contains enzymes belonging to the cysteine proteases of the papain family. Numerous studies have been reported aiming at the fractionation and characterization of the many molecular species present in the extract, but more efforts are still required to obtain sufficient quantities of the various purified protease forms for detailed physicochemical, enzymatic and structural characterization. In this work, we describe an efficient strategy towards the purification of at least eight enzymatic forms. Thus, following rapid fractionation on a SP-Sepharose FF column, two sub-populations with proteolytic activity were obtained: the unbound (termed acidic) and bound (termed basic) bromelain fractions. Following reversible modification with monomethoxypolyethylene glycol (mPEG), both fractions were further separated on Q-Sepharose FF and SP-Sepharose FF, respectively. This procedure yielded highly purified molecular species, all titrating ca. 1 mol of thiol group per mole of enzyme, with distinct biochemical properties. N-terminal sequencing allowed identifying at least eight forms with proteolytic activity. The basic fraction contained previously identified species, i.e. basic bromelain forms 1 and 2, ananain forms 1 and 2, and comosain (MEROPS identifier: C01.027). Furthermore, a new proteolytic species, showing similarities with basic bomelain forms 1 and 2, was discovered and termed bromelain form 3. The two remaining species were found in the acidic bromelain fraction and were arbitrarily named acidic bromelain forms 1 and 2. Both, acidic bromelain forms 1, 2 and basic bromelain forms 1, 2 and 3 are glycosylated, while ananain forms 1 and 2, and comosain are not. The eight protease forms display different amidase activities against the various substrates tested, namely small synthetic chromogenic compounds (DL-BAPNA and Boc-Ala-Ala-Gly-pNA), fluorogenic compounds (like Boc-Gln-Ala-Arg-AMC, Z-Arg-Arg-AMC and Z-Phe-Arg-AMC), and proteins (azocasein and azoalbumin), suggesting a specific organization of their catalytic residues. All forms are completely inhibited by specific cysteine and cysteine/serine protease inhibitors, but not by specific serine and aspartic protease inhibitors, with the sole exception of pepstatin A that significantly affects acidic bromelain forms 1 and 2. For all eight protease forms, inhibition is also observed with 1,10-phenanthrolin, a metalloprotease inhibitor. Metal ions (i.e. Mn2+, Mg2+ and Ca2+) showed various effects depending on the protease under consideration, but all of them are totally inhibited in the presence of Zn2+. Mass spectrometry analyses revealed that all forms have a molecular mass of ca. 24 kDa, which is characteristic of enzymes belonging to the papain-like proteases family. Far-UV CD spectra analysis further supported this analysis. Interestingly, secondary structure calculation proves to be highly reproducible for all cysteine proteases of the papain family tested so far (this work; see also Azarkan et al., 2011; Baeyens-Volant et al., 2015) and thus can be used as a test for rapid identification of the classical papain fold. [less ▲]Detailed reference viewed: 24 (0 ULiège) Rigid catheters reduced duration of less invasive surfactant therapy procedures in manikins.RIGO, Vincent ; Debauche, Christian; Maton, Pierre et alin Acta Paediatrica (2017)Aim: Different catheters can be used for less invasive surfactant therapy (LIST): feeding tubes inserted with or without Magill forceps, different angiocatheters and centre specific devices, such as ... [more ▼]Aim: Different catheters can be used for less invasive surfactant therapy (LIST): feeding tubes inserted with or without Magill forceps, different angiocatheters and centre specific devices, such as umbilical catheters affixed to a stylet. This study compared the effectiveness of LIST devices and endotracheal tubes (ETT). Methods: Video recordings of 20 neonatologists simulating different LIST techniques on two manikin heads were analysed. Procedural effectiveness was evaluated by the duration of procedures and failure rates. Ease of use was scored. Results: The median procedure time for the Neonatal Intubation Trainer was significantly longer with feeding tubes without Maggil forceps. For the more difficult ALS Baby Trainer, successful procedures lasted a median of 24 (17-32) seconds with ETT, 24 (15-36) seconds with stylet-guided catheters and 34 (27-46) seconds and 37 (29-42) seconds with 13cm and 30cm angiocatheters, respectively. Both methods using feeding tubes were statistically slower than ETT intubation, lasting 32 (25-44) seconds and 39 (27-95) seconds with or without Maggil forceps. Failure rates (7-20%) were no different between the LIST methods. Techniques using feeding tubes were rated as more difficult. Conclusion: Only rigid or stylet-guided catheters required tracheal catheterisation times similar to those of endotracheal intubation and neonatologists found them easier.  KEY NOTES • This manikin study used video recordings of 20 neonatologists to compare the effectiveness of devices for less invasive surfactant therapy (LIST) and endotracheal tubes. • The durations of tracheal catheterisation for LIST using rigid or stylet-guided catheters were no different from those obtained with endotracheal tubes, but feeding tubes with or without Maggil forceps required longer procedures. • Neonatologists found rigid or stylet-guided catheters easier to use. [less ▲]Detailed reference viewed: 30 (1 ULiège) Perspective: Essential Study Quality Descriptors for Data from Nutritional Epidemiologic ResearchYang, Chen; Pinart, Mariona; Kolsteren, Patrick et alin Advances in Nutrition (2017)Detailed reference viewed: 17 (0 ULiège) A useful result related with zeros of continuous compactly supported mother waveletsAyache, Antoine; Esser, Céline in Latin American Journal of Probability and Mathematical Statistics (2017), 15(5), In the last two decades, wavelet bases and associated methodologies have become quite important in many domains, such as signal and image processing, harmonic analysis, statistics, and so on. More ... [more ▼]In the last two decades, wavelet bases and associated methodologies have become quite important in many domains, such as signal and image processing, harmonic analysis, statistics, and so on. More recently, they also turn out to be quite useful in the probabilistic framework of stochastic processes, in which, among other things, they allow to obtain fine results concerning erratic sample paths behavior. The goal of our article is to derive a result, related with zeros of continuous compactly supported mother wavelets, which is useful in this probabilistic framework. More precisely, let $\psi$ be any arbitrary such wavelet; we show that being given an arbitrary point $x_0\in\R$ there always exists at least one integer $k_{x_0}\in\Z$ such that $\psi(x_0-k_{x_0}) \neq 0$. [less ▲]Detailed reference viewed: 31 (5 ULiège) Glioblastoma stem cells and the importance of endolysosomes to keep them in the nichesRogister, Bernard in Translational Cancer Research (2017), 6(Suppl 1), 87-89Detailed reference viewed: 23 (0 ULiège) Prediction-focused approaches: an opportunity for hydrologyHermans, Thomas in Groundwater (2017), 55(5), 683-687Our ability to predict the evolution of complex hydrological system is fundamental. For decades, such problems have been solved by calibrating a conceptual model of the subsurface to fit data ... [more ▼]Our ability to predict the evolution of complex hydrological system is fundamental. For decades, such problems have been solved by calibrating a conceptual model of the subsurface to fit data. Unfortunately, model calibration does not allow a realistic uncertainty quantification, whereas stochastic inversion is often computationally prohibitive. In this contribution, prediction-focused approaches (PFAs) are introduced to overcome those main shortcomings. This new paradigm focused on generating predictions directly from the data instead of generating models. A group of prior models is used to generate the data and the prediction in order to derive a direct relationship between both types of variables. The advantages, limitations and research perspectives are discussed. [less ▲]Detailed reference viewed: 65 (13 ULiège)