References of "Scientific journals"
     in
Bookmark and Share    
Full Text
See detailLe bouleau, une essence qui s'impose. Description de la ressource dans son aire de distribution
Dubois, Héloïse ULg; Latte, Nicolas ULg; Lecomte, Hugues et al

in FORÊT.NATURE (2016), 140

L'essentiel de la ressource en bouleau (verruqueux et pubescent) se situe en Russie et en Scandinavie (15 milliards de m³) et cette ressource augmente graduellement depuis plusieurs années. Il y est ... [more ▼]

L'essentiel de la ressource en bouleau (verruqueux et pubescent) se situe en Russie et en Scandinavie (15 milliards de m³) et cette ressource augmente graduellement depuis plusieurs années. Il y est fortement valorisé en sciage, déroulage et trituration. En Europe de l'Ouest, cette croissance s'observe aussi, même si seulement 1 % de la ressource s'y concentre (dû notamment à la plus grande diversité d'essences commerciales présentes). En Wallonie, les évolutions du contexte socio-économique et environnemental jouent en faveur d'une augmentation de la présence du bouleau (parcelles non reboisées, entretien insuffisant, mélanges spontanés...). Le bouleau représente souvent une belle opportunité pour les mélanges, une excellente essence d'accompagnement et une diversification de la production. Mais, sans une sylviculture adaptée, les grumes sont généralement de faible dimension et présentent de nombreux défauts. C'est le cas de l'essentiel de la ressource actuelle en Wallonie. Aujourd'hui, les besoins sont de mieux le connaître, notamment les opportunités de valorisation, et d'aboutir à des recommandations sylvicoles. Il ne s'agit donc pas de vouloir faire du bouleau à tout prix mais plutôt de tirer profit d'une étape transitoire de la succession forestière. [less ▲]

Detailed reference viewed: 36 (9 ULg)
Full Text
Peer Reviewed
See detailEntreprise sociale et économie sociale en Asie (Partie II)
Bidet, Eric; Defourny, Jacques ULg; Nyssens, Marthe (eds)

in Revue Internationale de l'Economie Sociale : Recma, Revue des Etudes Coopératives, Mutualistes et Associatives (2016), (n° 342),

Detailed reference viewed: 24 (1 ULg)
Full Text
Peer Reviewed
See detailA case of added value of 123I-mIBG SPECT/CT imaging in the diagnosis of a pheochromocytoma extending into the left adrenal vein
PAQUES, Florence ULg; HAMOIR, Etienne ULg; LOVINFOSSE, Pierre ULg et al

in Acta Chirurgica Belgica (2016)

We present the case of a 48-year-old patient with a left adrenal incidentaloma found on computed tomography (CT) for which the diagnosis of pheochromocytoma was confirmed by a 24-hour urinary dosage of ... [more ▼]

We present the case of a 48-year-old patient with a left adrenal incidentaloma found on computed tomography (CT) for which the diagnosis of pheochromocytoma was confirmed by a 24-hour urinary dosage of norepinephrine. The 123I-mIBG scintigraphy showed a high uptake of 123I-mIBG in the left adrenal gland and, additionally, the single photon emission computed tomography combined with a low-dose CT (SPECT/CT) suggested the extension into the adrenal vein. The diagnostic CT and magnetic resonance images agreed with these findings and the subsequent surgery confirmed the vascular invasion. [less ▲]

Detailed reference viewed: 23 (3 ULg)
Full Text
Peer Reviewed
See detailPhenology of farmed seaweed Kappaphycus alvarezii infestation by the parasitic epiphyte Polysiphonia sp. in Madagascar
Tsiresy, Gaëtan; Preux, Jérémy; Lavitra, Thierry et al

in Journal of Applied Phycology (2016), 28(5), 29032914

epiphytic filamentous algae (EFA) disease has appeared in many regions of Madagascar. This infestation has dramatic consequences for local farmers as it alters drastically farmed algal growth and has ... [more ▼]

epiphytic filamentous algae (EFA) disease has appeared in many regions of Madagascar. This infestation has dramatic consequences for local farmers as it alters drastically farmed algal growth and has caused farming activity to collapse in many places. The present study characterizes the structure and ultrastructure of the stages observed in the life cycle of Polysiphonia sp. and gives the results of a monitoring of 18 months made in three Kappaphycus alvarezii farming sites in the southwest of Madagascar. Transmission electron microscopy (TEM) was used to analyze the ultrastructure of the cortex in infested K. alvarezii. Five stages have been observed in the life cycle of Polysiphonia sp.: the infesting stage that is a small dark spot observed at the surface of K. alvarezii, the male gametophyte, the female gametophyte, the tetrasporocysts, and the undifferentiated stage where individuals show normal thalli without sexual differentiation. EFA infestation was never recorded in Sarodrano, but often in the two other monitored villages (Lambohara, Tampolove). Prevalence of infestation varied from 40 to 100 % and the rates of infestation from 42 to 78 epiphytes cm−2. Prevalence of infestation showed significant seasonal variation and a between-sites variation; the rates of infestation were not significantly different between sites and did not vary with the period. The ways of infestation between K. alvarezii individuals in an infested field and from infested to healthy fields are discussed at the light of the present results. [less ▲]

Detailed reference viewed: 92 (2 ULg)
Full Text
Peer Reviewed
See detailL’évaluation de la formation : comment la rendre utile pour les participants ? Constats et proposition de cinq stratégies d’évaluation partenariale
Faulx, Daniel ULg; Danse, Cédric ULg

in Evaluer : Journal International de Recherche en Education et Formation (2016), 2(1), 37-52

L’évaluation de la formation par les participants est une pratique courante aujourd’hui, portée à la fois par des exigences de rentabilité et de qualité. Cependant, cet exercice, qui se présente ... [more ▼]

L’évaluation de la formation par les participants est une pratique courante aujourd’hui, portée à la fois par des exigences de rentabilité et de qualité. Cependant, cet exercice, qui se présente souvent sous la forme de questionnaires individuels remis à la fin de la formation, peut être vécu par ceux qui les remplissent comme un rituel obligé mais présentant peu d’intérêt. C’est dans l’intention de proposer une alternative à cette situation que cet article a été rédigé. Dans un premier temps, nous faisons le point sur les modes les plus habituels d’évaluation de la formation par les participants. Nous identifions les récurrences de ce genre de pratique et les questions qu’elles posent. Ensuite, nous avançons cinq manières de procéder à une évaluation de telle sorte qu’elle soit bénéfique tant aux apprenants qu’au formateur. Les propositions sont réparties en deux familles (centrée sur l’activité de l’apprenant et centrée sur le processus de formation). Elles visent, au contraire de ce qui est pratiqué habituellement, à mettre au travail chacun des acteurs, formateur comme apprenants, afin que le moment de l’évaluation constitue une occasion de continuer à apprendre. Cette approche est aussi potentiellement transférable en contexte scolaire lors de l’évaluation des enseignants (ou des enseignements) par les élèves/étudiants. [less ▲]

Detailed reference viewed: 95 (7 ULg)
Full Text
Peer Reviewed
See detailLong-Term Results of 18 Fat Injections in Unilateral Vocal Fold Paralysis
PAGANO, Rémi ULg; Morsomme, Dominique ULg; CAMBY, Séverine ULg et al

in Journal of Voice (2016)

Summary: Objective. The purposes of this study were to assess the long-term efficacy of medialization laryngo- plasty via injection of autologous fat in patients with unilateral laryngeal paralysis, and ... [more ▼]

Summary: Objective. The purposes of this study were to assess the long-term efficacy of medialization laryngo- plasty via injection of autologous fat in patients with unilateral laryngeal paralysis, and to discuss the results based on the volume of fat injected and the size of the initial glottic gap. Study design. This was a retrospective study with clinical reevaluation of 18 patients treated for unilateral laryn- geal paralysis at Liège University Hospital between April 1, 2011, and December 1, 2014. Method. The voice examination included subjective scales (GRBAS and the Voice Handicap Index), a report on acous- tic and aerodynamic voice parameters, and laryngostroboscopic assessment of glottic closure and mucosal wave (T0: preoperative; T1: immediate postoperative; T2: >1 year). Results. The median follow-up duration was 19 months. We observed a significant improvement in maximum pho- nation time; mean flow rate; jitter; the Voice Handicap Index; the G, R, B, and A subscales of the GRBAS-I; and glottic closure at T1. These parameters remained stable over time, without any significant difference except for shimmer and glottic closure between T1 and T2. Regardless of the volume of fat injected and the magnitude of the initial glottic gap, we did not see any significant difference from one assessment time to another. Conclusion. Medialization laryngoplasty by means of the injection of autologous fat is a safe, effective surgical tech- nique for patients with unilateral laryngeal paralysis regardless of the size of the initial glottic gap. The results are maintained longer than 1 year, and no evidence of significant resorption of the fat was found in our study over a period of 12–58 months. The volume of fat injected does not seem to affect the functional results. Key Words: Glottic insufficiency–Glottic closure–Glottic gap–Laryngeal paralysis–Vocal fold paralysis–Laryngoplasty– Autologous fat–Fat injection. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailQuantitative Three-Dimensional Color Flow Echocardiography of Chronic Mitral Regurgitation: New Methods, New Perspectives, New Challenges
zhou, x; vannan, m; LANCELLOTTI, Patrizio ULg

in Journal of the American Society of Echocardiography (2016), 29(10), 935-937

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailApparition de la puberté chez les agneaux mâles de race Ouled Djellal
Boussena, Sabrina; Bouaziz, O.; Hireche, S. et al

in Revue de Médecine Vétérinaire (2016), 167(9-10), 274-282

The aim of this study is to evaluate the body and testicular growth performances in Ouled Djellal rams from weaning until twelve months of age. It also contributes to the study of the onset of puberty in ... [more ▼]

The aim of this study is to evaluate the body and testicular growth performances in Ouled Djellal rams from weaning until twelve months of age. It also contributes to the study of the onset of puberty in Ouled Djellal rams and to follow the subsequent evolution of their semen production. Weekly measurements of body weight, chest perimeter, scrotal circumference, testicular length and diameter, as well as the cauda-epididymis diameter of the gonads were conducted in ten rams, from weaning and until the onset of puberty. Semen collection was also performed in the same manner with an electroejaculator in order to define puberty. After the onset of puberty, observations were made fortnightly on body weight, chest perimeter, testis morphometry and the evolution of semen characteristics. Puberty settled at an average age of 228± 7 days with an average weight of 40.4 ± 1.2 kg. Highly significant correlations were observed between testicular measurements and those of the body. Similar significant correlations were also observed between testicular measurements (especially scrotal circumference) and semen characteristics after puberty. [less ▲]

Detailed reference viewed: 41 (10 ULg)
Full Text
Peer Reviewed
See detailL’approche sémiotique de Charles Goodwin : langage visuel, énonciation et diagramme
Dondero, Maria Giulia ULg

in Tracés. Revue de Sciences Humaines (2016), 3(automne),

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by ... [more ▼]

This text investigates the connexion between the work of Charles Goodwin and contemporary semiotics. I initially address the relations between verbal, visual, and gestural languages in semiotic terms by exploring the Goodwin’s notational system (transcription of exchanges) from the point of view of its constituent units. Secondly, I consider the meeting points between Goodwin’s concept of the substrate and Fontanille’s enunciative praxis in order to examine the dynamic relationship between sedimentation and transformation. Finally, I analyse the concept of diagrammatic reasoning by elaborating on the example of the geologists’ “first inscriptions” studied by Goodwin. The form of diagrammatic reasoning examined here functions as a discovery device that exemplifies the dynamics of sedimentation and novelty, and it can thus be studied in the framework of Goodwin’s transcription practices. [less ▲]

Detailed reference viewed: 39 (0 ULg)
Full Text
Peer Reviewed
See detailDon et dette de vie à l'adolescence
Haxhe, Stéphanie ULg; de Saint Georges, Marie-Christine; Michard, Pierre et al

in Adolescence (2016), 34(3), 597-605

L’adolescent récuse la dette de vie et réclame autonomie et considération. Néanmoins, la société actuelle offre à l’adolescent des parents fragilisés. La réalité de l’adolescent contemporain apparaît ... [more ▼]

L’adolescent récuse la dette de vie et réclame autonomie et considération. Néanmoins, la société actuelle offre à l’adolescent des parents fragilisés. La réalité de l’adolescent contemporain apparaît alors comme une quête en tension entre une nécessaire appropriation de lui-même et des dons discrets à ses parents. Si ces dons ne sont pas reçus et échouent à introduire parents et adolescent à une nouvelle position relationnelle, le risque d’un épuisement de l’adolescent est à prendre en considération. [less ▲]

Detailed reference viewed: 40 (6 ULg)
Full Text
Peer Reviewed
See detailLa revue Poétique
Lorent, Fanny ULg

in La revue des revues (2016), 56

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailInternational Trade Sanctions related to Dual-Use Goods and Technologies
Colussi, Ilaria Anna ULg

in Athens Journal of Law (2016), 2(4), 237-252

One of the basic rules in trade law is the freedom of trade. However, such rule encounters some limitations when the object of trade is constituted by strategic items, such as dual-use items, which may ... [more ▼]

One of the basic rules in trade law is the freedom of trade. However, such rule encounters some limitations when the object of trade is constituted by strategic items, such as dual-use items, which may have peaceful (civilian/commercial) or non peaceful/military applications. Trade of these categories of goods needs to be controlled, as they can provoke security concerns. Such control is pursued through control lists, licenses, authorizations to stakeholders of the supply chain, information- sharing and cooperation mechanisms, reports, records, declarations, screenings and sanctions as well. The paper aims at focusing on the issue of sanctions, in particular the ones established at the international level: these measures are provided for the violation of trade rules in reference to dual-use items, and/or sanctions have as an object this type of goods. The legal provisions established by the World Trade Organization (WTO) and at the United Nations level are analysed thereafter. Brief observations are offered as regards the EU framework of restrictive measures too. [less ▲]

Detailed reference viewed: 27 (5 ULg)
Full Text
Peer Reviewed
See detailTransnational Ageing and the ‘Zero Generation’: The Role of Moroccan Migrants’ Parents in Care Circulation
Zickgraf, Caroline ULg

in Journal of Ethnic and Migration Studies (2016)

This article emphasizes the impacts of international migration on ageing processes and norms within transnational families, and, specifically, analyses the roles of the zero generation, defined as the ... [more ▼]

This article emphasizes the impacts of international migration on ageing processes and norms within transnational families, and, specifically, analyses the roles of the zero generation, defined as the parents of first-generation migrants (Nedelcu 2009), both as non-migrant counterparts to their children abroad and as ageing migrants themselves. Transnational caregiving research has demonstrated that for many migrants and their families care arrangements must be negotiated across national borders, yet the agency of transnational older adults has been largely neglected. Based on qualitative fieldwork conducted from 2011 to 2013 in Liège, Belgium and Oujda, Morocco, the present article examines the circulation of care between Moroccan adult migrants and their ageing ascendants. This article exposes the duality of migrants’ ascendants as care givers and recipients, asserting firstly, that receiving care is not synonymous with passivity, and that, secondly, migrants’ ascendants are also the initiators of transnational practices. In both roles, this article underlines mobility as a strategy used by migrants’ parents to maintain family solidarity across national borders, but that this care mobility is limited by macro-level migration policies, here exemplified by the Belgian migration regime. [less ▲]

Detailed reference viewed: 2 (1 ULg)
Full Text
Peer Reviewed
See detailLE MÉDICAMENT DU MOIS Dapagliflozine (Forxiga®) Inhibiteur des cotransporteurs rénaux SGLT2, nouvel agent anti-hyperglycémiant dans le diabète de type 2
SCHEEN, André ULg

in Revue Médicale de Liège (2016), 71(10), 463-469

Résumé : La dapagliflozine, un inhibiteur spécifique des cotransporteurs sodium-glucose de type 2 (SGLT2), inhibe la réabsorption tubulaire rénale du glucose et accroît la gluco¬surie. Il en résulte une ... [more ▼]

Résumé : La dapagliflozine, un inhibiteur spécifique des cotransporteurs sodium-glucose de type 2 (SGLT2), inhibe la réabsorption tubulaire rénale du glucose et accroît la gluco¬surie. Il en résulte une diminution de la glycémie et du taux d’hémoglobine glyquée (HbA1c), avec un risque faible d’hypo¬glycémie, une perte pondérale et une diminution de la pression artérielle. L’efficacité sur la réduction du taux d’HbA1c est d’autant plus importante que l’hyperglycémie est élevée, mais elle diminue en cas d’insuffisance rénale. Les infections géni¬tales mycotiques sont plus fréquentes, surtout chez la femme, alors que l’augmentation des infections urinaires basses n’est que marginale. La dapagliflozine (Forxiga®), commercialisée à la dose de 10 mg une fois par jour, est indiquée pour le trai¬tement du diabète de type 2 et remboursée en Belgique, sous conditions, en ajout à la metformine, un sulfamide ou le répa-glinide, une association metformine-sulfamide/répaglinide ou une insuline basale avec au moins un antidiabétique oral. Des données préliminaires ne démontrent pas d’augmentation du risque cardiovasculaire par rapport au comparateur et suggèrent même une protection cardiovasculaire et rénale, à confirmer dans l’essai DECLARE, une grande étude prospec¬tive contrôlée actuellement en cours chez des patients diabé¬tiques de type 2 à haut risque cardiovasculaire. [less ▲]

Detailed reference viewed: 38 (6 ULg)
Full Text
Peer Reviewed
See detailCo-simulation of Electromagnetic Transients and Phasor Models: a Relaxation Approach
Plumier, Frédéric ULg; Aristidou, Petros; Geuzaine, Christophe ULg et al

in IEEE Transactions on Power Delivery (2016), 31(5),

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this ... [more ▼]

Co-simulation opens new opportunities to combine mature ElectroMagnetic Transients (EMT) and Phasor-Mode (PM) solvers, and take advantage of their respective high accuracy and execution speed. In this paper, a relaxation approach is presented, iterating between an EMT and a PM solver. This entails interpolating over time the phasors of the PM simulation, extracting phasors from the time evolutions of the EMT simulation, and representing each sub-system by a proper multiport equivalent when simulating the other sub-system. Various equivalents are reviewed and compared in terms of convergence of the PM-EMT iterations. The paper also considers the update with frequency of the Thévenin impedances involved in the EMT simulation, the possibility to compute the EMT solution only once per time step, and the acceleration of convergence through a prediction over time of the boundary variables. Results are presented on a 74-bus, 23-machine test system, split into one EMT and one PM sub-system with several interface buses. [less ▲]

Detailed reference viewed: 296 (23 ULg)
Full Text
See detailUne approche psychocriminologique de la radicalisation : le modèle de «transformation cognitivo-affective de la définition de soi et de la construction du sens dans l’engagement radical violent»
Garcet, Serge ULg

in Revue de la Faculté de Droit de l'Université de Liège (2016), 3

La question de la radicalisation violente renvoie à un champ de recherches transdisciplinaire qui nécessite d’articuler les niveaux micro, méso et macro d’analyse. Dans cette perspective, après avoir ... [more ▼]

La question de la radicalisation violente renvoie à un champ de recherches transdisciplinaire qui nécessite d’articuler les niveaux micro, méso et macro d’analyse. Dans cette perspective, après avoir interrogé la place faite aux variables individuelles dans les principaux modèles explicatifs du processus de radicalisation, l’article envisage comment la capacité d’autodétermination du sujet et sa capacité à agir sur lui-même autant que sur son environnement transforment progressivement les cognitions et nourrissent la motivation à s’engager. Les principes de cette interaction complexe entre la personne et son environnement sont synthétisés dans le modèle original de «transformation cognitivo-affective de la définition de soi et de la construction du sens dans l’engagement radical violent ». [less ▲]

Detailed reference viewed: 266 (45 ULg)
Full Text
See detail"De regels moeten soepeler" : Interview met Vlaams Bouwmeester Leo Van Broeck
De Visscher, Lisa ULg

in A+ : Architecture in Belgium (2016), 262

Leo Van Broeck of the architecture office Bogdan & Van Broeck is the new Flemish Government Architect since early September. A + probed its policy for the next four years, and then in particular his view ... [more ▼]

Leo Van Broeck of the architecture office Bogdan & Van Broeck is the new Flemish Government Architect since early September. A + probed its policy for the next four years, and then in particular his view of what a productive city can be. We have banned the industry out of the city for decades. Now we note that a healthy and balanced mix of functions is an important condition for a functioning urban cohesion. The manufacturing industry certainly has its place in the city and can have a positive impact both on an urban and an ecological level. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailShift in the chemical composition of dissolved organic matter in the Congo River network
Lambert, Thibault ULg; Bouillon, S.; Darchambeau, François ULg et al

in Biogeosciences (2016), 13(18), 5405-5420

The processing of terrestrially derived dissolved organic matter (DOM) during downstream transport in fluvial networks is poorly understood. Here, we report a dataset of dissolved organic carbon (DOC ... [more ▼]

The processing of terrestrially derived dissolved organic matter (DOM) during downstream transport in fluvial networks is poorly understood. Here, we report a dataset of dissolved organic carbon (DOC) concentrations and DOM composition (stable carbon isotope ratios, absorption and fluorescence properties) acquired along a 1700 km transect in the middle reach of the Congo River Basin. Samples were collected in the mainstem and its tributaries during high water (HW) and falling water (FW) periods. DOC concentrations and DOM composition along the mainstem were found to differ between the two periods, because of a reduced lateral mixing between the central water masses of the Congo River and DOM-rich waters from tributaries and also likely because of a greater photodegradation during FW as water residence time (WRT) increased. Although the Cuvette Centrale wetland (one of the world’s largest flooded forest) continuously releases highly aromatic DOM in streams and rivers of the Congo Basin, the downstream transport of DOM was found to result in an along stream gradient from aromatic to aliphatic compounds. The characterization of DOM through parallel factor analysis (PARAFAC) suggests that this transition results from (1) the losses of aromatic compounds by photodegradation and (2) the production of aliphatic compounds by biological reworking of terrestrial DOM. Finally, this study highlights the critical importance of the river-floodplain connectivity in tropical rivers in controlling DOM biogeochemistry at large spatial scale and suggests that the degree of DOM processing during downstream transport is a function of landscape characteristics and WRT [less ▲]

Detailed reference viewed: 28 (4 ULg)
Full Text
Peer Reviewed
See detailFirst characterization and validation of FORLI-HNO3 vertical profiles retrieved from IASI/Metop
Ronsmans, G.; Langerock, B.; Wespes, C. et al

in Atmospheric Measurement Techniques (2016), 16

Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions ... [more ▼]

Knowing the spatial and seasonal distributions of nitric acid (HNO3) around the globe is of great interest to apprehend the processes regulating stratospheric ozone, especially in the polar regions. Thanks to its unprecedented spatial and temporal sampling, the nadir-viewing Infrared Atmospheric Sounding Interferometer (IASI) allows sounding the atmosphere twice a day globally, with good spectral resolution and low noise. With the Fast Optimal Retrievals on Layers for IASI (FORLI) algorithm, we are retrieving, in near-real time, columns as well as vertical profiles of several atmospheric species, amongst which is HNO3. We present in this paper the first characterization of the FORLI-HNO3 profile products, in terms of vertical sensitivity and error budgets. We show that the sensitivity of IASI to HNO3 is highest in the lower stratosphere (10–20km), where the largest amounts of HNO3 are found, but that the vertical sensitivity of IASI only allows one level of information on the profile (DOFS 1). The sensitivity near the surface is negligible in most cases, and for this reason, a partial column (5–35km) is used for the analyses. Both vertical profiles and partial columns are compared to FTIR ground-based measurements from the Network for the Detection of Atmospheric Composition Change (NDACC) to characterize the accuracy and precision of the FORLI-HNO3 product. The profile validation is conducted through the smoothing of the raw FTIR profiles by the IASI averaging kernels and gives good results, with a slight overestimation of IASI measurements in the Upper Troposphere-Lower Stratosphere (UTLS) at the 6 chosen stations (Thule, Kiruna, Jungfraujoch, Izaña, Lauder and Arrival Heights). The validation of the partial columns (5–35km) is also conclusive with a mean correlation of 0.93 between IASI and the FTIR measurements. An initial survey of the HNO3 spatial and seasonal variabilities obtained from IASI measurements for a one year (2011) data set shows that the expected latitudinal gradient of concentrations from low to high latitudes and the large seasonal variability in polar regions (cycle amplitude around 30% of the seasonal signal, peak-to-peak) are well represented with IASI data. [less ▲]

Detailed reference viewed: 35 (9 ULg)
Full Text
Peer Reviewed
See detailNuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury.
Jouret, François ULg; Leenders, Justine ULg; Defraigne, Jean-Olivier ULg et al

in PLoS ONE (2016), 11(9), 1-14

Abstract BACKGROUND: Ischemia/reperfusion (I/R) is the most common cause of acute kidney injury (AKI). Its pathophysiology remains unclear. Metabolomics is dedicated to identify metabolites involved in ... [more ▼]

Abstract BACKGROUND: Ischemia/reperfusion (I/R) is the most common cause of acute kidney injury (AKI). Its pathophysiology remains unclear. Metabolomics is dedicated to identify metabolites involved in (patho)physiological changes of integrated living systems. Here, we performed 1H-Nuclear Magnetic Resonance metabolomics using urine, serum and kidney samples from a mouse model of renal I/R. METHODS: Renal 30-min ischemia was induced in 12-week-old C57BL/6J male mice by bilaterally clamping vascular pedicles, and was followed by 6, 24 or 48-hour reperfusion (n = 12/group). Sham-operated mice were used as controls. Statistical discriminant analyses, i.e. principal component analysis and orthogonal projections to latent structures (OPLS-DA), were performed on urine, serum and kidney lysates at each time-point. Multivariate receiver operating characteristic (ROC) curves were drawn, and sensitivity and specificity were calculated from ROC confusion matrix (with averaged class probabilities across 100 cross-validations). RESULTS: Urine OPLS-DA analysis showed a net separation between I/R and sham groups, with significant variations in levels of taurine, di- and tri-methylamine, creatine and lactate. Such changes were observed as early as 6 hours post reperfusion. Major metabolome modifications occurred at 24h post reperfusion. At this time-point, correlation coefficients between urine spectra and conventional AKI biomarkers, i.e. serum creatinine and urea levels, reached 0.94 and 0.95, respectively. The area under ROC curve at 6h, 24h and 48h post surgery were 0.73, 0.98 and 0.97, respectively. Similar discriminations were found in kidney samples, with changes in levels of lactate, fatty acids, choline and taurine. By contrast, serum OPLS-DA analysis could not discriminate sham-operated from I/R-exposed animals. CONCLUSIONS: Our study demonstrates that renal I/R in mouse causes early and sustained metabolomic changes in urine and kidney composition. The most implicated pathways at 6h and 24h post reperfusion include gluconeogenesis, taurine and hypotaurine metabolism, whereas protein biosynthesis, glycolysis, and galactose and arginine metabolism are key at 48h post reperfusion. [less ▲]

Detailed reference viewed: 48 (19 ULg)
Full Text
Peer Reviewed
See detailDouble-slit experiment in momentum space
Ivanov, Igor ULg; Seipt, Daniel; Surzhykov, Andrey et al

in Europhysics Letters (2016), 115(4), 41001

Young's classic double-slit experiment demonstrates the reality of interference when waves and particles travel simultaneously along two different spatial paths. Here, we propose a double-slit experiment ... [more ▼]

Young's classic double-slit experiment demonstrates the reality of interference when waves and particles travel simultaneously along two different spatial paths. Here, we propose a double-slit experiment in momentum space, realized in the free-space elastic scattering of vortex electrons. We show that this process proceeds along two paths in momentum space, which are well localized and well separated from each other. For such vortex beams, the (plane-wave) amplitudes along the two paths acquire adjustable phase shifts and produce interference fringes in the final angular distribution. We argue that this experiment can be realized with the present-day technology. We show that it gives experimental access to the Coulomb phase, a quantity which plays an important role in all charged particle scattering but which usual scattering experiments are insensitive to. [less ▲]

Detailed reference viewed: 4 (1 ULg)
Full Text
Peer Reviewed
See detailIncreasing the salience of fluency cues does not reduce the recognition memory impairment in Alzheimer’s disease!
Simon, Jessica ULg; Bastin, Christine ULg; SALMON, Eric ULg et al

in Journal of Neuropsychology (2016)

In Alzheimer’s disease (AD), it is now well established that recollection is impaired from the beginning of the disease, whereas findings are less clear concerning familiarity. One of the most important ... [more ▼]

In Alzheimer’s disease (AD), it is now well established that recollection is impaired from the beginning of the disease, whereas findings are less clear concerning familiarity. One of the most important mechanisms underlying familiarity is the sense of familiarity driven by processing fluency. In this study, we attempted to attenuate recognition memory deficits in AD by maximizing the salience of fluency cues in two conditions of a recognition memory task. In one condition, targets and foils have been created from the same pool of letters (Overlap condition). In a second condition, targets and foils have been derived from two separate pools of letters (No-Overlap condition), promoting the use of letter-driven visual and phonetic fluency. Targets and foils were low-frequency words. The memory tasks were performed by 15 patients with AD and 16 healthy controls. Both groups improved their memory performance in the No-Overlap condition compared to the Overlap condition. Patients with AD were able to use fluency cues during recognition memory as older adults did, but this did not allow to compensate for dysfunction of recognition memory processes. [less ▲]

Detailed reference viewed: 32 (9 ULg)
Full Text
Peer Reviewed
See detailImpacts of ikaite export from sea ice to the underlying seawater in a sea ice-seawater mesocosm
Geilfus, N.-X.; Galley, R. J.; Else, B. G. T. et al

in Cryosphere (The) (2016), 10

Ikaite precipitation within sea ice could act as a significant sink for atmospheric CO2. However, the fate of these ikaite crystals is still poorly understood. We quantify temporal inorganic carbon ... [more ▼]

Ikaite precipitation within sea ice could act as a significant sink for atmospheric CO2. However, the fate of these ikaite crystals is still poorly understood. We quantify temporal inorganic carbon dynamics from initial sea ice formation from open water to its melt during a month-long experiment in a sea ice-seawater mesocosm pool. Within sea ice, ikaite precipitation and CO2 exchange with the atmosphere were the main processes affecting inorganic carbon dynamics, while the dissolution of ikaite was the main process affecting inorganic carbon dynamics in the underlying seawater. Based on the total alkalinity (TA) and total dissolved inorganic carbon (TCO2) within sea ice and seawater, we estimated ikaite precipitated up to 167 ± 3 µmol kg-1 within sea ice; up to 57 % of the ikaite precipitated within sea ice was exported to the underlying seawater where it was dissolved. Ikaite export from the ice to the underlying seawater was associated with brine rejection during sea ice growth, increased sea ice vertical connectivity due to the upward percolation of seawater, and meltwater flushing during sea ice melt. The dissolution of the ikaite crystals in the water column kept the seawater pCO2 undersaturated compared to the atmosphere in spite of increased salinity, TA, and TCO2 associated with sea ice growth. Results indicate that ikaite export from sea ice and its dissolution in the underlying seawater can potentially hamper the effect of oceanic acidification on the aragonite saturation state (Ωaragonite) in fall and winter in ice-covered areas, at the time when Ωaragonite is smallest. [less ▲]

Detailed reference viewed: 57 (7 ULg)
Full Text
Peer Reviewed
See detailT2-weighted MRI signal predicts hormone and tumor responses to somatostatin analogs in acromegaly.
Potorac, Iulia ULg; PETROSSIANS, Patrick ULg; Daly, Adrian ULg et al

in Endocrine-Related Cancer (2016), 23(11), 871881

GH-secreting pituitary adenomas can be hypo-, iso- or hyperintense on T2-weighted MRI sequences. We conducted the current multicenter study in a large population of patients with acromegaly to analyze the ... [more ▼]

GH-secreting pituitary adenomas can be hypo-, iso- or hyperintense on T2-weighted MRI sequences. We conducted the current multicenter study in a large population of patients with acromegaly to analyze the relationship between T2-weighted signal intensity on diagnostic MRI and hormonal and tumoral responses to somatostatin analogs (SSA) as primary monotherapy. Acromegaly patients receiving primary SSA for at least 3 months were included in the study. Hormonal, clinical and general MRI assessments were performed and assessed centrally. We included 120 patients with acromegaly. At diagnosis, 84, 17 and 19 tumors were T2-hypo-, iso- and hyperintense, respectively. SSA treatment duration, cumulative and mean monthly doses were similar in the three groups. Patients with T2-hypointense adenoma had median SSA-induced decreases in GH and IGF-1 of 88% and 59% respectively, which were significantly greater than the decreases observed in the T2-iso- and hyperintense groups (p<0.001). Tumor shrinkage on SSA was also significantly greater in the T2-hypointense group (38%) compared with the T2-iso- and hyperintense groups (8% and 3%, respectively; p<0.0001). The response to SSA correlated with the calculated T2-intensity: the lower the T2-weighted intensity, the greater the decrease of random GH (p<0.0001, r=0.22), IGF-1 (p<0.0001, r=0.14) and adenoma volume (p<0.0001, r=0.33). The T2-weighted signal intensity of GH-secreting adenomas at diagnosis correlates with the hormone reduction and tumor shrinkage in response to primary SSA treatment in acromegaly. This study supports its use as a generally available predictive tool at diagnosis that could help to guide subsequent treatment choices in acromegaly. [less ▲]

Detailed reference viewed: 34 (9 ULg)
Full Text
Peer Reviewed
See detailLes déclarations non vérifiées de témoins au regard du procès équitable
Michiels, Olivier ULg; Falque, Géraldine ULg

in Journal des Tribunaux (2016), (6656), 485-490

Dans l’arrêt Schatschaschwili contre Allemagne, la Cour européenne des droits de l’homme s’est particulièrement attachée à préciser les principes qui s’appliquent aux déclarations d’un témoin absent au ... [more ▼]

Dans l’arrêt Schatschaschwili contre Allemagne, la Cour européenne des droits de l’homme s’est particulièrement attachée à préciser les principes qui s’appliquent aux déclarations d’un témoin absent au procès, susceptibles de fonder la culpabilité d’un accusé. Les éclaircissements que l’arrêt de la Grande Chambre ambitionne d’apporter à ce sujet retiendront notre attention dès lors que l’équité du procès pourrait être compromise par la déposition d’un témoin que la défense n’a pas pu, directement ou indirectement, faire interroger. Après avoir rappelé le contexte factuel et procédural dans lequel s’inscrit la cause, nous tenterons de dégager les lignes de force de l’arrêt commenté. Enfin, nous nous efforcerons de mettre ces enseignements en perspective avec la jurisprudence de la cour de Cassation relative à l’article 6, § 3, d) de la Convention qui reconnaît notamment le droit à tout accusé d’interroger ou faire interroger un témoin à charge, pour terminer par une brève conclusion. [less ▲]

Detailed reference viewed: 40 (4 ULg)
Full Text
Peer Reviewed
See detailDelay Compensation for Real Time Disturbance Estimation at Extremely Large Telescopes
Bohm, Michael; Pott, Jorg-Uwe; Kurster, Martin et al

in IEEE Transactions on Control Systems Technology (2016), PP(99), 10

In ground-based astronomy, aberrations due to structural vibrations, such as piston, limit the achievable resolution and cannot be corrected using adaptive optics (AO) for large telescopes. We present a ... [more ▼]

In ground-based astronomy, aberrations due to structural vibrations, such as piston, limit the achievable resolution and cannot be corrected using adaptive optics (AO) for large telescopes. We present a model-free strategy to estimate and compensate piston aberrations due to the vibrations of optical components using accelerometer disturbance feed forward, eventually allowing the use of fainter guide stars both for the fringe detector and in the AO loop. Because the correction performance is very sensitive to signal delays, we present a strategy to add a delay compensation to the developed disturbance estimator, which can, in principle, be applied to many other applications outside of astronomy that lack observer performance due to a measurement delay or need a prediction to compensate for input delays. The ability to estimate vibration disturbances in the critical frequency range of 8-60 Hz is demonstrated with on sky data from the Large Binocular Telescope (LBT) Interferometer, an interferometer at the LBT. The experimental results are promising, indicating the ability to suppress differential piston induced by telescope vibrations by a factor of about 3 (rms), which is significantly better than any currently commissioned system. [less ▲]

Detailed reference viewed: 25 (2 ULg)
Full Text
Peer Reviewed
See detailSteady-state and dynamic validation of a small scale waste heat recovery system using the ThermoCycle Modelica library
Desideri, Adriano ULg; Hernandez, Andres; Gusev, Sergei et al

in Energy (2016), 115

The organic Rankine cycle (ORC) power system has been recognized as a promising technology for micro power applications. In this context, physics-based dynamic models can constitute a significant tool for ... [more ▼]

The organic Rankine cycle (ORC) power system has been recognized as a promising technology for micro power applications. In this context, physics-based dynamic models can constitute a significant tool for the further development of the technology, allowing to evaluate and optimize response times during transients, or to implement and test innovative control strategies. In this contribution, the dynamic model of an ORC power unit based on the ThermoCycle Modelica library is validated against steady-state and transient experimental results from an 11 kWel stationary ORC system. The simulation results are in good agreement with the measurements, both in steady-state and in transient conditions. The validated library is readily usable to investigate demanding dynamics-based problems for low capacity power systems. [less ▲]

Detailed reference viewed: 26 (7 ULg)
Full Text
Peer Reviewed
See detailAcoustic indices provide information on the status of coral reefs: an example from Moorea Island in the South Pacific
Bertucci, Frédéric; Parmentier, Eric ULg; Lecellier, Gaël et al

in Scientific Reports (2016), 6(33326), 1-9

Detailed reference viewed: 33 (3 ULg)
Full Text
Peer Reviewed
See detailActivating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell–derived lymphomas
Vallois, David; Dobay, Maria Pamela D.; Morin, Ryan D. et al

in Blood (2016), 128

Angioimmunoblastic T-cell lymphoma (AITL) and other lymphomas derived from follicular T-helper cells (TFH) represent a large proportion of peripheral T-cell lymphomas (PTCLs) with poorly understood ... [more ▼]

Angioimmunoblastic T-cell lymphoma (AITL) and other lymphomas derived from follicular T-helper cells (TFH) represent a large proportion of peripheral T-cell lymphomas (PTCLs) with poorly understood pathogenesis and unfavorable treatment results. We investigated a series of 85 patients with AITL (n 5 72) or other TFH-derived PTCL (n 5 13) by targeted deep sequencing of a gene panel enriched in T-cell receptor (TCR) signaling elements. RHOA mutations were identified in 51 of 85 cases (60%) consisting of the highly recurrent dominant negative G17V variant in most cases and a novel K18N in 3 cases, the latter showing activating properties in in vitro assays. Moreover, half of the patients carried virtually mutually exclusive mutations in other TCR-related genes, most frequently in PLCG1 (14.1%), CD28 (9.4%, exclusively in AITL), PI3K elements (7%), CTNNB1 (6%), and GTF2I (6%). Using in vitro assays in transfected cells, we demonstrated that 9 of 10 PLCG1 and 3 of 3 CARD11 variants induced MALT1 protease activity and increased transcription from NFAT or NF-kB response element reporters, respectively. Collectively, the vast majority of variants in TCR-related genes could be classified as gain-of-function. Accordingly, the samples with mutations in TCR-related genes other than RHOA had transcriptomic profiles enriched in signatures reflecting higher T-cell activation. Although no correlationwithpresenting clinical featuresnor significantimpacton survivalwasobserved, thepresenceofTCR-relatedmutations correlated with early disease progression. Thus, targeting of TCR-related eventsmay hold promise for the treatment of TFH-derived lymphomas. [less ▲]

Detailed reference viewed: 25 (2 ULg)
Full Text
Peer Reviewed
See detailPredicting the dynamic impact behaviour of spray droplets on flat plant surfaces
Delele, Mulugeta Admasu; Nuyttens, David; Douga, Ashenafitilahun T. et al

in Soft Matter (2016), 12 (34)(7), 195-211

The dynamic impact behaviour of water droplets on plant surfaces was investigated based on a multiphase computational fluid dynamics (CFD) model. The study was conducted using the Volume Of Fluid (VOF ... [more ▼]

The dynamic impact behaviour of water droplets on plant surfaces was investigated based on a multiphase computational fluid dynamics (CFD) model. The study was conducted using the Volume Of Fluid (VOF) approach. The static contact angle of water droplets on leaf surfaces of different plants (apple, pear, leek and cabbage) was measured and found to vary between 54.9 and 138.2°. Impact experiments were conducted by monitoring the flow and impact characteristics of water droplets on leaves in still air with a high speed camera. Droplets were generated by an agricultural flat fan spray nozzle moving across the leaf at constant speed. The nozzle produced droplets with diameters ranging from 20.6 up to 550.8 μm, and droplet velocity values near the impact between 0.03 and 13.2 m s(-1). The CFD model was capable of predicting the observed dynamic impact behaviour of droplets on the plant surfaces. The fate of the droplets after the impact process for adhesion, bouncing or splashing was accurately predicted for Weber numbers (We) in the range of 0.007 to 1096 and droplet Reynolds numbers (Re) between 5 to 8000. The process was highly dependent on the surface and droplet flow characteristics during the impact. Combinations of We, Re and Ohnesorge (Oh) numbers defined the droplet maximum spread factor, the number of secondary droplets generated as a result of the splashing process and the transition between the different impact outcomes. These criteria can then be used in field scale spray deposition and drift models to better understand agricultural spray operations. [less ▲]

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailMoisture content determination in an antibody-drug conjugate freeze-dried medicine by near-infrared spectroscopy: a case study for release testing
Clavaud, Matthieu ULg; Roggo, Yves; Dégardin, Klara et al

in Journal of Pharmaceutical & Biomedical Analysis (2016), 131

The use of Near-infrared spectroscopy (NIRS) as a fast and non-destructive technique was employed for moisture content (MC) determination in Antibody-drug conjugates (ADCs) in replacement to Karl Fischer ... [more ▼]

The use of Near-infrared spectroscopy (NIRS) as a fast and non-destructive technique was employed for moisture content (MC) determination in Antibody-drug conjugates (ADCs) in replacement to Karl Fischer (KF) method. The lab analysis of ADCs, high potent medicines, should be performed in conditions ensuring the operator’s safety and using secured analytical tools like NIRS. A NIRS method was first developed and validated in compliance with current guidelines. The novelty of this work first lies in the large number of samples prepared for a wide moisture calibration range of 0.51% to 4.01%. Then, the classical Partial Least Square (PLS) regression was used as chemometric tool for the computation of the model. Excellent predictive calibration results were shown. A coefficient of correlation (r) value of 0.99 was obtained. An intercept value of 0.02 and a slope of 0.99 were observed, while the root mean square error of calibration (RMSEC) and the root mean square error of prediction (RMSEP) were respectively 0.10% and 0.12%. In addition, instrumentation, model performances and robustness of the method were evaluated, demonstrating the validation results. Calibration transfer issue and impact of the number of samples were also evaluated. Consequently, a validation strategy was introduced as a basis for submission to the health authorities’ for release and stability activities in a cGMP environment in replacement of the KF method. [less ▲]

Detailed reference viewed: 34 (18 ULg)
Full Text
Peer Reviewed
See detailDirect measurement of evapotranspiration from a forest using a superconducting gravimeter
Van Camp, Michel; de Viron, Olivier; Pajot-Métivier, Gwendoline et al

in Geophysical Research Letters (2016), 43

Evapotranspiration (ET) controls the flux between the land surface and the atmosphere. Assessing the ET ecosystems remains a key challenge in hydrology. We have found that the ET water mass loss can be ... [more ▼]

Evapotranspiration (ET) controls the flux between the land surface and the atmosphere. Assessing the ET ecosystems remains a key challenge in hydrology. We have found that the ET water mass loss can be directly inferred from continuous gravity measurements: as water evaporates and transpires from terrestrial ecosystems, the mass distribution of water decreases, changing the gravity field. Using continuous superconducting gravity measurements, we were able to identify daily gravity changes at the level of, or smaller than, 10-9 nms-2 (or 10-10 g) per day. This corresponds to 1.7mmof water over an area of 50 ha. The strength of this method is its ability to enable a direct, traceable and continuous monitoring of actual ET for years at the mesoscale with a high accuracy. [less ▲]

Detailed reference viewed: 28 (9 ULg)
Full Text
Peer Reviewed
See detailEffects of equine chorionic gonadotropin (eCG) on the sexual behaviour and ovulatory characteristics of female african N'Dama cattle.
Okouyi, M.W. Marcel; Hanzen, Christian ULg

in Revue de Médecine Vétérinaire (2016), 167(7-8), 211-215

This paper evaluated the effects of eCG on the characteristics of oestrus and ovulation after heifers and cows had been synchronised following vaginal administration of progesterone for seven days ... [more ▼]

This paper evaluated the effects of eCG on the characteristics of oestrus and ovulation after heifers and cows had been synchronised following vaginal administration of progesterone for seven days (Controlled Internal Drug Released) and a PGF2α injection two days after the end of treatment. The animals were randomly split into a non-treated control group (n=26) and four groups with increasing doses of eCG: 300 IU (n=25), 400 IU (n=24), 500 IU (n=23) and 600 IU (n=23), which were injected on the day of CIDR withdrawal. The animals were then followed (24 hours a day) for six days. Oestrus was confirmed on the basis of identifying 'standing oestrus', i.e., when the cow stood to be mounted. Seven to ten days after the CIDR® was withdrawn, the animals were slaughtered, and their ovaries were examined to identify and count the number of follicular and/or luteal structures. The onset of heat was 48.6 ± 5.3 hours after eCG injection, and the average length of oestrus was 9.9 ± 2 hours. The eCG dosage had no significant effect on these two parameters. In contrast, the observed rate of oestrus was significantly (p<0.05) higher in animals that had been treated (70.8 to 84.0%) in comparison with animals that had not been treated (50%). Similarly, the ovulation rate was significantly (p<0.05) higher in treated animals (88.0 to 100%) than in untreated animals (73.1%). The percentage of animals that presented multiple ovulations increased significantly (p <0.001) with the dosage of eCG administered (4.5% to 36.4%). [less ▲]

Detailed reference viewed: 30 (13 ULg)
Full Text
Peer Reviewed
See detailRaised interferon beta, type 3 interferon and interferon stimulated genes - evidence of innate immune activation in neutrophilic asthma.
da Silva, J.; Hilzendeger, Clarissa ULg; Moermans, Catherine et al

in Clinical & Experimental Allergy : Journal of the British Society for Allergy & Clinical Immunology (2016)

BACKGROUND: Interferons play an important role in innate immunity. Previous studies report deficiency in virus-induction of interferon (IFN)-alpha, -beta and -lambda in bronchial epithelial and bronchial ... [more ▼]

BACKGROUND: Interferons play an important role in innate immunity. Previous studies report deficiency in virus-induction of interferon (IFN)-alpha, -beta and -lambda in bronchial epithelial and bronchial lavage cells in atopic asthmatics. It is now recognized that asthma is a heterogeneous disease comprising different inflammatory phenotypes, some of which may involve innate immune activation in the absence of overt infection. OBJECTIVE: The aim of the study was investigate if the severity of asthma or a specific cellular sputum pattern may be linked to evidence of innate immune activation. METHODS: Here we investigate the expression of IFN-beta, IFN-lambda1 (IL-29), IFN-lambda2/3 (IL-28A/B) and the interferon-stimulated genes (ISGs) myxovirus resistance 1 (Mx1), oligoadenylate synthetase (OAS) and viperin in unstimulated sputum cells in 57 asthmatics (including 16 mild, 19 moderate and 22 severe asthma patients) and compared them with 19 healthy subjects. RESULTS: We observed increased expression of IFN-beta, IFN-lambda1/IL-29, OAS and viperin in asthmatic compared to healthy subjects while IL-28 was not expressed in any group. The overexpression was restricted to neutrophilic asthmatics (sputum neutrophils >/= 76%) while eosinophilic asthmatics (sputum eosinophils >/= 3%) did not differ from healthy subjects or even showed a lower expression of Mx1. No difference in interferon or ISG expression was seen according to clinical asthma severity. CONCLUSION AND CLINICAL RELEVANCE: Neutrophilic, but not eosinophilic, asthmatics display overexpression of IFN-beta, IFN-lambda1/IL-29 and ISGs in their sputum cells that may reflect ongoing innate immune activation. This article is protected by copyright. All rights reserved. [less ▲]

Detailed reference viewed: 19 (4 ULg)
Full Text
Peer Reviewed
See detailComparative study of nutritional quality of potato-wheat steamed and baked breads made with four cultivated potato flour
Liu, Xingli; Mu, Tai-Hua; Sun, Hongnan et al

in International Journal of Food Sciences & Nutrition (2016)

Bread is traditional staple food in western and oriental countries varying in both the ingredients used, preparation methods, and heating methods applied, which are mainly used as an energy source because ... [more ▼]

Bread is traditional staple food in western and oriental countries varying in both the ingredients used, preparation methods, and heating methods applied, which are mainly used as an energy source because of high carbohydrate. Baked bread is popular in western countries. While steamed bread is a type of fermented and steamed wheat-based food of Chinese origin, and represents ∼40% of the wheat consumption in China. [less ▲]

Detailed reference viewed: 114 (19 ULg)
Full Text
Peer Reviewed
See detailAxIOM: Amphipod crustaceans from insular Posidonia oceanica seagrass meadows
Michel, Loïc ULg; Sturaro, Nicolas ULg; Heughebaert, André et al

in Biodiversity Data Journal (2016), 4

Background The Neptune grass, Posidonia oceanica (L.) Delile, 1813, is the most widespread seagrass of the Mediterranean Sea. This foundation species forms large meadows that, through habitat and trophic ... [more ▼]

Background The Neptune grass, Posidonia oceanica (L.) Delile, 1813, is the most widespread seagrass of the Mediterranean Sea. This foundation species forms large meadows that, through habitat and trophic services, act as biodiversity hotspots. In Neptune grass meadows, amphipod crustaceans are one of the dominant groups of vagile invertebrates, forming an abundant and diverse taxocenosis. They are key ecological components of the complex, pivotal, yet critically endangered Neptune grass ecosystems. Nevertheless, comprehensive qualitative and quantitative data about amphipod fauna found in Mediterranean Neptune grass meadows remain scarce, especially in insular locations. New information Here, we provide in-depth metadata about AxIOM, a sample-based dataset published on the GBIF portal. AxIOM is based on an extensive and spatially hierarchized sampling design with multiple years, seasons, day periods, and methods. Samples were taken along the coasts of Calvi Bay (Corsica, France) and of the Tavolara-Punta Coda Cavallo Marine Protected Area (Sardinia, Italy). In total, AxIOM contains 187 samples documenting occurrence (1775 records) and abundance (10720 specimens) of amphipod crustaceans belonging to 72 species spanning 29 families. The dataset is available at http://ipt.biodiversity.be/resource?r=axiom. [less ▲]

Detailed reference viewed: 22 (2 ULg)
Full Text
Peer Reviewed
See detailApplication of GRACE to the assessment of model-based estimates of monthly Greenland Ice Sheet mass balance (2003–2012)
Schlegel, N.; Wiese, D.; Larour, E. et al

in Cryosphere (The) (2016), 10

Quantifying the Greenland Ice Sheet's future contribution to sea level rise is a challenging task that requires accurate estimates of ice sheet sensitivity to climate change. Forward ice sheet models are ... [more ▼]

Quantifying the Greenland Ice Sheet's future contribution to sea level rise is a challenging task that requires accurate estimates of ice sheet sensitivity to climate change. Forward ice sheet models are promising tools for estimating future ice sheet behavior, yet confidence is low because evaluation of historical simulations is challenging due to the scarcity of continental-wide data for model evaluation. Recent advancements in processing of Gravity Recovery and Climate Experiment (GRACE) data using Bayesian-constrained mass concentration ("mascon") functions have led to improvements in spatial resolution and noise reduction of monthly global gravity fields. Specifically, the Jet Propulsion Laboratory's JPL RL05M GRACE mascon solution (GRACE_JPL) offers an opportunity for the assessment of model-based estimates of ice sheet mass balance (MB) at ∼ 300 km spatial scales. Here, we quantify the differences between Greenland monthly observed MB (GRACE_JPL) and that estimated by state-of-the-art, high-resolution models, with respect to GRACE_JPL and model uncertainties. To simulate the years 2003–2012, we force the Ice Sheet System Model (ISSM) with anomalies from three different surface mass balance (SMB) products derived from regional climate models. Resulting MB is compared against GRACE_JPL within individual mascons. Overall, we find agreement in the northeast and southwest where MB is assumed to be primarily controlled by SMB. In the interior, we find a discrepancy in trend, which we presume to be related to millennial-scale dynamic thickening not considered by our model. In the northwest, seasonal amplitudes agree, but modeled mass trends are muted relative to GRACE_JPL. Here, discrepancies are likely controlled by temporal variability in ice discharge and other related processes not represented by our model simulations, i.e., hydrological processes and ice–ocean interaction. In the southeast, GRACE_JPL exhibits larger seasonal amplitude than predicted by the models while simultaneously having more pronounced trends; thus, discrepancies are likely controlled by a combination of missing processes and errors in both the SMB products and ISSM. At the margins, we find evidence of consistent intra-annual variations in regional MB that deviate distinctively from the SMB annual cycle. Ultimately, these monthly-scale variations, likely associated with hydrology or ice–ocean interaction, contribute to steeper negative mass trends observed by GRACE_JPL. Thus, models should consider such processes at relatively high (monthly-to-seasonal) temporal resolutions to achieve accurate estimates of Greenland MB. [less ▲]

Detailed reference viewed: 42 (3 ULg)
Full Text
Peer Reviewed
See detailEnabling efficient PET imaging of Synaptic Vesicle glycoprotein 2A (SV2A) with a robust and one-step radiosynthesis of a highly potent 18F-labelled ligand ([18F]UCB-H)
Warnier, Corentin ULg; Lemaire, Christian ULg; Becker, Guillaume ULg et al

in Journal of Medicinal Chemistry (2016), 59

We herein describe the straightforward synthesis of a stable pyridyl(4- methoxyphenyl)iodonium salt and its [18F]radiolabelling within a one-step, fully automated and cGMP compliant radiosynthesis of [18F ... [more ▼]

We herein describe the straightforward synthesis of a stable pyridyl(4- methoxyphenyl)iodonium salt and its [18F]radiolabelling within a one-step, fully automated and cGMP compliant radiosynthesis of [18F]UCB-H ([18F]7), a PET tracer for the imaging of Synaptic Vesicle glycoprotein 2A (SV2A). Over the course of one year, 50 automated productions provided 34±2% of injectable [18F]7 from up to 285 GBq (7.7 Ci) of [18F]fluoride in 50 minutes (uncorrected radiochemical yield. Specific Activity = 815±185 GBq/μmol). The successful implementation of our synthetic strategy within routine, high-activity and cGMP productions attests to its practicality and reliability for the production of large doses of [18F]7. In addition to enabling efficient and cost-effective clinical research on a range of neurological pathologies through the imaging of SV2A, this work further demonstrates the real value of iodonium salts for the cGMP 18F-PET tracer manufacturing industry, and their ability to fulfill practical and regulatory requirements in that field. [less ▲]

Detailed reference viewed: 46 (12 ULg)
Full Text
Peer Reviewed
See detailThe Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission.
Santos da Silva, Eveline; Mulinge, Martin; Lemaire, Morgane et al

in PLoS ONE (2016)

The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in ... [more ▼]

The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in this domain. To address this issue, we compared the replication of recombinant virus pairs carrying the full Env (Env viruses) or the Env ectodomain fused to the gp41CT of NL4.3 (EnvEC viruses) (12 subtype C and 10 subtype B pairs) in primary CD4+ T-cells and monocyte-derived-macrophages (MDMs). In CD4+ T-cells, replication was as follows: B-EnvEC = B-Env>C-EnvEC>C-Env, indicating that the gp41CT of subtype C contributes to the low replicative capacity of this subtype. In MDMs, in contrast, replication capacity was comparable for all viruses regardless of subtype and of gp41CT. In CD4+ T-cells, viral entry, viral release and viral gene expression were similar. However, infectivity of free virions and cell-to-cell transmission of C-Env viruses released by CD4+ T-cells was lower, suggestive of lower Env incorporation into virions. Subtype C matrix only minimally rescued viral replication and failed to restore infectivity of free viruses and cell-to-cell transmission. Taken together, these results show that polymorphisms in the gp41CT contribute to viral replication capacity and suggest that the number of Env spikes per virion may vary across subtypes. These findings should be taken into consideration in the design of vaccines. [less ▲]

Detailed reference viewed: 18 (4 ULg)
Full Text
Peer Reviewed
See detailBiomarkers of inflammation and innate immunity in atrophic nonunion fracture
DE SENY, Dominique ULg; COBRAIVILLE, Gaël ULg; Leprince, Pierre ULg et al

in Journal of Translational Medicine (2016)

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailSeasonal variability of surface and column carbon monoxide over megacity Paris, high-altitude Jungfraujoch and Southern Hemispheric Wollongong stations
Té, Y; Jeseck, P; Franco, Bruno ULg et al

in Atmospheric Chemistry and Physics (2016), 16

This paper studies the seasonal variation of surface and column CO at three different sites (Paris, Jungfraujoch and Wollongong), with an emphasis on establishing a link between the CO vertical ... [more ▼]

This paper studies the seasonal variation of surface and column CO at three different sites (Paris, Jungfraujoch and Wollongong), with an emphasis on establishing a link between the CO vertical distribution and the nature of CO emission sources. We find the first evidence of a time lag between surface and free tropospheric CO seasonal variations in the Northern Hemisphere. The CO seasonal variability obtained from the total columns and free tropospheric partial columns shows a maximum around March–April and a minimum around September–October in the Northern Hemisphere (Paris and Jungfraujoch). In the Southern Hemisphere (Wollongong) this seasonal variability is shifted by about 6 months. Satellite observations by the IASI–MetOp (Infrared Atmospheric Sounding Interferometer) and MOPITT (Measurements Of Pollution In The Troposphere) instruments confirm this seasonality. Ground-based FTIR (Fourier transform infrared) measurements provide useful complementary information due to good sensitivity in the boundary layer. In situ surface measurements of CO volume mixing ratios at the Paris and Jungfraujoch sites reveal a time lag of the near-surface seasonal variability of about 2 months with respect to the total column variability at the same sites. The chemical transport model GEOS-Chem (Goddard Earth Observing System chemical transport model) is employed to interpret our observations. GEOS-Chem sensitivity runs identify the emission sources influencing the seasonal variation of CO. At both Paris and Jungfraujoch, the surface seasonality is mainly driven by anthropogenic emissions, while the total column seasonality is also controlled by air masses transported from distant sources. At Wollongong, where the CO seasonality is mainly affected by biomass burning, no time shift is observed between surface measurements and total column data. [less ▲]

Detailed reference viewed: 94 (9 ULg)
Full Text
Peer Reviewed
See detailConsumption patterns, bacteriological quality and risk factors for Salmonella contamination in meat-based meals consumed outside the home in Kigali, Rwanda
Niyonzima, Eugène; Ongol, Martin Patrick; Brostaux, Yves ULg et al

in Food Control (2016)

Meat-based meals are consumed as a source of animal proteins and constitute one of the leading vehicles for food borne infections in humans. The main objective of this study was to determine the ... [more ▼]

Meat-based meals are consumed as a source of animal proteins and constitute one of the leading vehicles for food borne infections in humans. The main objective of this study was to determine the consumption pattern and the bacteriological quality of meat-based meals consumed outside households in Kigali. A survey on meat consumption patterns was carried out in 400 households by using a questionnaire, whereas different meat-based meals were sampled from 150 snack bars and restaurants. Enumeration of hygiene indicator bacteria (total mesophilic bacteria and Escherichia coli) and the qualitative detection of Salmonella were carried out by using conventional culture methods. The results indicated that goat was the type of meat that was consumed the most outside the home in Kigali and the meat intake varied significantly (p ≤0.05) with the social category of the household. The average levels of total aerobic bacteria and E. coli in meat-based meals were found to be 4.7 and 1.4 log cfu/g, respectively, whereas Salmonella was detected in 11.7% of all meat-based meals. Eight factors mostly linked to the cooking treatments and hygienic handling practices for cooked meals were found to be significantly (p ≤ 0.05) associated with the risk of Salmonella occurrence in meat-based meals consumed outside the home in Kigali. The findings from this study strongly suggest the need for proper cooking and/or improvements in hygiene in the establishments selling ready-to-eat meat-based meals in Kigali, particularly those located in rural localities. [less ▲]

Detailed reference viewed: 36 (6 ULg)
Full Text
Peer Reviewed
See detailChaotic Bohmian trajectories for stationary states
Cesa, Alexandre ULg; Martin, John ULg; Struyve, Ward

in Journal of Physics A: Mathematical and Theoretical (2016), 49

In Bohmian mechanics, the nodes of the wave function play an important role in the generation of chaos. However, so far, most of the attention has been on moving nodes; little is known about the ... [more ▼]

In Bohmian mechanics, the nodes of the wave function play an important role in the generation of chaos. However, so far, most of the attention has been on moving nodes; little is known about the possibility of chaos in the case of stationary nodes. We address this question by considering stationary states, which provide the simplest examples of wave functions with stationary nodes. We provide examples of stationary wave functions for which there is chaos, as demonstrated by numerical computations, for one particle moving in 3 spatial dimensions and for two and three entangled particles in two dimensions. Our conclusion is that the motion of the nodes is not necessary for the generation of chaos. What is important is the overall complexity of the wave function. That is, if the wave function, or rather its phase, has complex spatial variations, it will lead to complex Bohmian trajectories and hence to chaos. Another aspect of our work concerns the average Lyapunov exponent, which quantifies the overall amount of chaos. Since it is very hard to evaluate the average Lyapunov exponent analytically, which is often computed numerically, it is useful to have simple quantities that agree well with the average Lyapunov exponent. We investigate possible correlations with quantities such as the participation ratio and different measures of entanglement, for different systems and different families of stationary wave functions. We find that these quantities often tend to correlate to the amount of chaos. However, the correlation is not perfect, because, in particular, these measures do not depend on the form of the basis states used to expand the wave function, while the amount of chaos does. [less ▲]

Detailed reference viewed: 24 (8 ULg)
Full Text
Peer Reviewed
See detailNON-DERMATOPHYTE DERMATOSES MIMICKING DERMATOPHYTOSES IN HUMANS
Libon, Florence ULg; TASSOUDJI, Nazli ULg; DEZFOULIAN, Bita ULg et al

in Mycopathologia (2016)

Human dermatophytic cutaneous infections usually present as single or multiple slowly progressing annular erythemato-squamous lesions with a tendency to central healing on the hairless skin. In the ... [more ▼]

Human dermatophytic cutaneous infections usually present as single or multiple slowly progressing annular erythemato-squamous lesions with a tendency to central healing on the hairless skin. In the intertriginous regions (feet, inguinal, axillar, submammary), dermatophytic colonisations and infections manifest as whitish, slightly hyperkeratotic, pruritic and sometimes fissurated lesions. On the scalp, dermatophytic infections commonly lead to single or multiple more or less inflammatory and alopecic lesions. On the plantar and palmar aspects of the feet and hand, dermatophytosis presents as an eczema-like chronic dermatosis. Abscess-like lesions may occur due to zoophilic dermatomycosis. Dermatophytic infections of the nails reveal ill-defined whitish-yellowish colorations of the distal end or the lateral aspects of the nails, sometimes combined with partial nail embrittlement or even complete destruction. Despite the ubiquity of dermatophytic skin infections and their usually highly typical clinical features, a differential diagnosis has to be considered, in particular when treatment is not efficient or when treatment resistance occurs. This review presents the differential diagnosis in terms of frequency as well as the diagnostic methods permitting the distinction of annular, intertriginous, alopecic, palmoplantar, abscess-like and onychodystrophic lesions. [less ▲]

Detailed reference viewed: 21 (5 ULg)
Full Text
Peer Reviewed
See detailMacro- and near-mesoporous monoliths by medium internal phase emulsion polymerization: a systematic study
Mathieu, Kevin ULg; Jérôme, Christine ULg; Debuigne, Antoine ULg

in Polymer (2016), 99

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were ... [more ▼]

The synthesis of a series of poly(ethylene oxide)-b-polystyrene copolymers with different block lengths was performed by radical addition fragmentation chain transfer. These amphiphilic copolymers were tested as stabilizers for water-in-oil medium internal phase emulsion (MIPE) templating polymerization and the formation of polyMIPEs with controlled morphology. Aside from the structure of the emulsion stabilizer, several parameters susceptible to influence the size of the cavities and the interconnectivity of the porous monoliths were probed including the choice of the comonomers, treatment of the emulsion by ultrasound, the use of controlled radical polymerization method for the network formation as well as interfacial initiation. Interconnected cellular monoliths were produced. The polymerization of the ultrasonicated water-in-ethylhexylacrylate/divinylbenzene MIPE notably led to near-mesoporous open-cell material. Mechanical properties and specific surface areas of the polyMIPEs were also investigated and discussed. [less ▲]

Detailed reference viewed: 32 (12 ULg)
Full Text
Peer Reviewed
See detailMagnetically confined wind shocks in X-rays - A review
ud-Doula, Asif; Nazé, Yaël ULg

in Advances in Space Research (2016), 58

A subset (∼ 10%) of massive stars present strong, globally ordered (mostly dipolar) magnetic fields. The trapping and channeling of their stellar winds in closed magnetic loops leads to magnetically ... [more ▼]

A subset (∼ 10%) of massive stars present strong, globally ordered (mostly dipolar) magnetic fields. The trapping and channeling of their stellar winds in closed magnetic loops leads to magnetically confined wind shocks (MCWS), with pre-shock flow speeds that are some fraction of the wind terminal speed. These shocks generate hot plasma, a source of X-rays. In the last decade, several developments took place, notably the determination of the hot plasma properties for a large sample of objects using XMM and Chandra, as well as fully self-consistent MHD modeling and the identification of shock retreat effects in weak winds. Despite a few exceptions, the combination of magnetic confinement, shock retreat and rotation effects seems to be able to account for X-ray emission in massive OB stars. Here we review these new observational and theoretical aspects of this X-ray emission and envisage some perspectives for the next generation of X-ray observatories. [less ▲]

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailLes supports des images : de la photographie à l’image numérique
Dondero, Maria Giulia ULg; Reyes, Everardo

in Revue Française des Sciences de l'Information et de la Communication (2016), 9

In this article we deal with questions related to images (painting, photography, digital image) from a semiotic standpoint, more precisely the form and substance of their expression plane. Classical ... [more ▼]

In this article we deal with questions related to images (painting, photography, digital image) from a semiotic standpoint, more precisely the form and substance of their expression plane. Classical greimasian semiotics –mainly through the works of Jean-Marie Floch (1985, 1986) and Félix Thürlemann (1982) – has concentrated on the relation between form of expression and form of content (thus in a semi-symbolic fashion). Then, in the 1990s, Jacques Fontanille started exploring the substance of expression. Later, within the framework of hierarchical levels of analysis, Fontanille (2005, 2008), introduced concepts such as material and formal support in order to distinguish between image as object and image as text. We take into account these works to study the close relationship between the substance of expression of images and the practices of production-reception. [less ▲]

Detailed reference viewed: 49 (3 ULg)
Full Text
Peer Reviewed
See detailThe Gaia-ESO Survey: revisiting the Li-rich giant problem
Casey, A. R.; Ruchti, G.; Masseron, T. et al

in Monthly Notices of the Royal Astronomical Society (2016), 461

The discovery of lithium-rich giants contradicts expectations from canonical stellar evolution. Here we report on the serendipitous discovery of 20 Li-rich giants observed during the Gaia-ESO Survey ... [more ▼]

The discovery of lithium-rich giants contradicts expectations from canonical stellar evolution. Here we report on the serendipitous discovery of 20 Li-rich giants observed during the Gaia-ESO Survey, which includes the first nine Li-rich giant stars known towards the CoRoT fields. Most of our Li-rich giants have near-solar metallicities and stellar parameters consistent with being before the luminosity bump. This is difficult to reconcile with deep mixing models proposed to explain lithium enrichment, because these models can only operate at later evolutionary stages: at or past the luminosity bump. In an effort to shed light on the Li-rich phenomenon, we highlight recent evidence of the tidal destruction of close-in hot Jupiters at the sub-giant phase. We note that when coupled with models of planet accretion, the observed destruction of hot Jupiters actually predicts the existence of Li-rich giant stars, and suggests that Li-rich stars should be found early on the giant branch and occur more frequently with increasing metallicity. A comprehensive review of all known Li-rich giant stars reveals that this scenario is consistent with the data. However, more evolved or metal-poor stars are less likely to host close-in giant planets, implying that their Li-rich origin requires an alternative explanation, likely related to mixing scenarios rather than external phenomena. [less ▲]

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailX-ray emission from interacting wind massive binaries: A review of 15 years of progress
Rauw, Grégor ULg; Nazé, Yaël ULg

in Advances in Space Research (2016), 58

Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind ... [more ▼]

Previous generations of X-ray observatories revealed a group of massive binaries that were relatively bright X-ray emitters. This was attributed to emission of shock-heated plasma in the wind-wind interaction zone located between the stars. With the advent of the current generation of X-ray observatories, the phenomenon could be studied in much more detail. In this review, we highlight the progress that has been achieved in our understanding of the phenomenon over the last 15 years, both on theoretical and observational grounds. All these studies have paved the way for future investigations using the next generation of X-ray satellites that will provide crucial information on the X-ray emission formed in the innermost part of the wind-wind interaction. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailProtection cardiovasculaire et rénale du patient diabétique de type 2 : le point après EMPA-REG OUTCOME et LEADER
SCHEEN, André ULg; PIERARD, Luc ULg; KRZESINSKI, Jean-Marie ULg et al

in Revue Médicale de Liège (2016), 71(09), 376-381

Summary : Type 2 diabetes (T2D), often associated with arterial hypertension, represents a high risk of cardiovascular disease and nephropathy. Two clinical trials demonstrate the superiority versus a ... [more ▼]

Summary : Type 2 diabetes (T2D), often associated with arterial hypertension, represents a high risk of cardiovascular disease and nephropathy. Two clinical trials demonstrate the superiority versus a placebo of two antidiabetic drugs in patients with T2D and high cardiovascular risk : empagliflozin, an inhibitor of sodium-glucose type 2 (SGLT2) cotransporters, in EMPA-REG OUTCOME and liraglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptors, in LEADER. Both medications showed a significant reduction in major cardiovascular events (-14 and -13 %, respectively), cardiovascular mortality (-38 and -22%), all-cause mortality (-32 and -15 %) and renal events (-39 et -22 %). The underlying protective mechanisms remain controverted. Ongoing studies should allow to decide whether the benefits are specific to each molecule or may be attributed to a class effect. [less ▲]

Detailed reference viewed: 46 (4 ULg)
Full Text
Peer Reviewed
See detailL’étau et le réseau. Recompositions des contextes de travail des équipes de direction pénitentiaire
Dubois, Christophe ULg

in Justice et Sécurité = Justitie en Veiligheid (2016), 7

Résumé : En parcourant les nombreuses études qui décrivent et analysent, depuis plus de vingt ans, le fonctionnement des organisations et des politiques pénitentiaires, trois questions semblent avoir ... [more ▼]

Résumé : En parcourant les nombreuses études qui décrivent et analysent, depuis plus de vingt ans, le fonctionnement des organisations et des politiques pénitentiaires, trois questions semblent avoir jusqu’ici suscité un moindre intérêt scientifique : qui dirige ces organisations ? En quoi consiste le travail des équipes de direction ? Quelle position les membres de ces équipes occupent-ils dans le système organisationnel et politique pénitentiaire belge ? Cet article apporte quelques éléments de réponse à ces questions tout en éclairant les recompositions des contextes de travail des équipes de direction pénitentiaire. Cet éclairage souligne la nécessité de définir politiquement et avec les principaux intéressés un processus de professionnalisation de la fonction qu’ils exercent. [less ▲]

Detailed reference viewed: 37 (1 ULg)
Full Text
Peer Reviewed
See detailDetailed characterization of the Late Pleistocene loess sequence stratigraphy of Remicourt (Hesbaye region, Belgium) with cone penetration tests
Delvoie, Simon ULg; Boulvain, Frédéric ULg; Charlier, Robert ULg et al

in Geologica Belgica (2016), 19(3-4), 281-289

Cone penetration tests (CPT) and drilling results are used to characterize the Middle Belgium loess sequence. A two scale study has been realized in the Hesbaye region (Belgium). The study on a regional ... [more ▼]

Cone penetration tests (CPT) and drilling results are used to characterize the Middle Belgium loess sequence. A two scale study has been realized in the Hesbaye region (Belgium). The study on a regional scale was performed along a 18 km long section of the high-speed railway Liège-Brussels. About 230 tests were compiled. Results show the loess thickness is very variable and can locally reach 20 m. Tertiary deposits become continuous and they rapidly thicken from Waremme to the West. The lower surface of the Tertiary deposits is characterized by a 0.3% apparent dipping to the NW. The dipping likely results from the Ardenne Massif uplift. The local scale study focuses on the site of Remicourt located along the high-speed railway. 24 CPT tests have been carried out very close to a series of archaeological trenches. The analysis shows penetrometers are able to define some stratigraphic markers within the loess layer. The most identifiable marker is stratigraphically located around the transition between the Humiferous Complex of Remicourt and the Rocourt Pedocomplex. The lens-shape of the loess ridge is also confirmed by the penetrometers’ interpretation. Furthermore, the 3D morphology of each stratigraphic marker can be estimated. These results offer interesting perspectives for the investigation of the loess sequence related to archaeological applications. [less ▲]

Detailed reference viewed: 15 (8 ULg)
Full Text
Peer Reviewed
See detailDiurnal variations of hormonal secretion, alertness and cognition in extreme chronotypes under different lighting conditions.
Maierova, L.; Borisuit, A.; Scartezzini, L et al

in Scientific Reports (2016)

Detailed reference viewed: 29 (2 ULg)
Full Text
Peer Reviewed
See detail« Oiseaux blessés. Avec les stagiaires d’Article 23 »
Melice, Anne ULg

in Centre Franco Basaglia – Liège, Mouvement pour une psychiatrie démocratique dans le milieu de vie. (2016)

Après une synthèse de récits de vie recueillis auprès de stagiaires rencontrés au sein des ateliers de l’Asbl Article 23 (Horeca et Bâtiment), ce texte décrit l’accueil qu’ils m’y ont réservé. Ce récit se ... [more ▼]

Après une synthèse de récits de vie recueillis auprès de stagiaires rencontrés au sein des ateliers de l’Asbl Article 23 (Horeca et Bâtiment), ce texte décrit l’accueil qu’ils m’y ont réservé. Ce récit se prolongera dans le texte suivant intitulé « ‘’Je te porte dans moi comme un oiseau blessé’’ (Aragon) », qui se fera l’écho de mon observation de l’hospitalité propre aux ateliers d’Article 23. [less ▲]

Detailed reference viewed: 64 (0 ULg)
Full Text
Peer Reviewed
See detailHousing Quality as Environmental Inequality: The Case of Wallonia, Belgium
Lejeune, Zoé ULg; Xhignesse, Guillaume ULg; Kryvobokov, Marko et al

in Journal of Housing and the Built Environment (2016), 31(3), 495-512

First in the USA and then in many other countries, scholarship on environmental inequality has sought to shed light on the unequal environmental conditions borne by poor people and ethnic minorities, and ... [more ▼]

First in the USA and then in many other countries, scholarship on environmental inequality has sought to shed light on the unequal environmental conditions borne by poor people and ethnic minorities, and to challenge public policies and their unjust impacts on those target groups. Housing quality, especially the indoor characteristics of homes, offers an innovative perspective in this field of research. In previous research on environmental inequality in the Walloon context, housing quality has been proven to be a major determinant of quality of life and environmental well-being. This paper analyses housing quality through a twofold approach: through indoor characteristics on the one hand, and outdoor subjective and objective externalities on the other. It reveals the disparities between the most deprived and the wealthiest segments of the population. The evidence for this study is based on a housing quality survey carried out in 2012 and 2013 on 6,018 households in Wallonia (Belgium). The key findings are that poor people are found to live in housing of lower quality, in densely populated neighbourhoods and those with mixed use, with compensating amenities provided at the local level. Moreover, consistent with environmental inequality scholarship, deprived households are found to bear the burden of environmental degradation outside the home. People live in areas with poorer air quality, but are found to benefit from greater access to green spaces. The results of the survey reveal an interesting point concerning the environmental inequality literature; the interior features of housing are found to differ more widely between deprived and wealthier people than the surrounding environment does. [less ▲]

Detailed reference viewed: 171 (82 ULg)
Full Text
See detailCoopération au service de la construction d'une qualité d'accueil
Pirard, Florence ULg

in Revue [Petite] Enfance (2016), 121

Les débats sur la qualité des lieux d’éducation et d’accueil des jeunes enfants (EAJE) font l’objet de nombreuses publications. S’il n’y a pas de consensus sur ce que recouvre précisément cette notion ... [more ▼]

Les débats sur la qualité des lieux d’éducation et d’accueil des jeunes enfants (EAJE) font l’objet de nombreuses publications. S’il n’y a pas de consensus sur ce que recouvre précisément cette notion polysémique, certaines orientations sont mises en avant par différentes instances internationales, comme l’Organisation de Coopération et de Développement Économique (OCDE, 2001, 2006, 2012, 2015) et l’Union Européenne (2015). Ces publications, à partir d’une consultation d’experts de différents pays et d’une revue de la littérature scientifique (essentiellement anglo-saxonne), soulignent notamment l’importance d’une meilleure accessibilité des services, d’une formation initiale et du développement professionnel continu, des conditions de travail adéquates, de lignes directrices claires inscrites dans un curriculum, d’un système d’évaluation et de monitoring de la qualité et, bien sûr, du soutien indispensable d’une gouvernance qui considère l’enfance comme un investissement plutôt que comme un coût. L’enjeu fondamental serait d’offrir aux enfants et à leurs familles des services de qualité dont les effets bénéfiques ne sont plus à démontrer, particulièrement pour celles en situation de précarité. La réalisation contextualisée de ces orientations générales dans un pays ou une région suppose la mise en place de démarches concertées à chaque niveau de responsabilité d’un système dit compétent (Urban et al., 2011) : individuel, institutionnel, interinstitutionnel et de gouvernance. Elle repose sur des formes de coopération et de participation inscrites dans un fonctionnement démocratique qui ne va pas nécessairement de soi. Notre article propose d’interroger ces formes de coopération et de participation attendues, de pointer une série d’obstacles à leur réalisation qu’il s’agit de parvenir à dépasser, mais aussi de relater des expériences qui témoignent d’un autre possible. Il s’appuie sur une revue de la littérature, mais se nourrit aussi des multiples rencontres que notre expérience professionnelle nous a permis de vivre dans différents contextes. [less ▲]

Detailed reference viewed: 23 (2 ULg)
Full Text
Peer Reviewed
See detailUnusual Species of Dermatophytes: Rarely Identified or New?
HAYETTE, Marie-Pierre ULg; SACHELI, Rosalie ULg

in Mycopathologia (2016)

Dermatophytes are causing superficial mycosis in animals and humans. Depending on the geophilic, zoophilic or anthropophilic origin of the fungus but also on the immunological status of the patient ... [more ▼]

Dermatophytes are causing superficial mycosis in animals and humans. Depending on the geophilic, zoophilic or anthropophilic origin of the fungus but also on the immunological status of the patient, symptomatology can widely differ. Nevertheless, each species is currently associated with typical clinical manifestations, even if atypical localizations and/or clinical pictures are sometimes also reported. Diagnostic tools applied to species identification have been changing since the last two decades with the more frequent use of molecular methods currently considered nowadays as reference methods for species identification. It becomes obvious that the algorithm used for the distinction of closely related species needs to combine phenotypic and genomic methods. All these different points are discussed, and the most recent novel species causing or involved in human dermatophytosis are reported. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailComment j'explore... une dysmorphose dento-maxillo-faciale.
Urbain, Valérie; GILON, Yves ULg; BRUWIER, Annick ULg et al

in Revue Médicale de Liège (2016), 71(9), 394-399

Dento-maxillofacial dysmorphoses represent a considerable area of maxillofacial surgery. Their incidence has constantly been on the rise since the beginning of the century. This can be explained by ... [more ▼]

Dento-maxillofacial dysmorphoses represent a considerable area of maxillofacial surgery. Their incidence has constantly been on the rise since the beginning of the century. This can be explained by variations in the food and society habits.We will first discuss the various causes (congenital and environnemental) and the pathophysiology of these disorders. Then, we will separate them according to the skeletal and Angle’s classifications. We will examine the predictive criteria of these dysmorphoses from the youngest age and consider their clinical and cephalometrical diagnosis We will envisage their functional and aesthetic consequences and expose the preventive options. Finally, we will describe the orthodontic and surgical treatment available today and conclude that surgery remains the gold standard by restoring the conventional axis. [less ▲]

Detailed reference viewed: 41 (5 ULg)
Full Text
Peer Reviewed
See detailHet net en het netwerk. Werkomgevingen van penitentiaire directieteams
Dubois, Christophe ULg; Winant, Ben

in Justice et Sécurité = Justitie en Veiligheid (2016), 7

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailL'EBM peut-elle encore enthousiasmer ?
Henrard, Gilles ULg

in Minerva: Tijdschrift Voor Evidence Based Medicine (2016)

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailLa vignette diagnostique de l’étudiant Mise au point d’une suspicion de malaise hypoglycémique chez une personne adulte non diabétique
SCHEEN, André ULg; PAQUOT, Nicolas ULg; LEFEBVRE, Pierre ULg

in Revue Médicale de Liège (2016), 71(09), 407-413

Résumé : La survenue de malaises est souvent attribuée à une hypoglycémie chez des personnes non diabétiques et, a priori, sans autre problème de santé. Ce diagnostic est, cependant, souvent galvaudé, car ... [more ▼]

Résumé : La survenue de malaises est souvent attribuée à une hypoglycémie chez des personnes non diabétiques et, a priori, sans autre problème de santé. Ce diagnostic est, cependant, souvent galvaudé, car habituellement non clairement démontré. Le diagnostic d’hypoglycémie doit se faire de façon structurée en se basant sur la triade de Whipple. Tout d’abord, l’anamnèse doit rechercher les symptômes évocateurs d’hypoglycémie, adrénergiques et neuroglucopéniques. Ensuite, l’hypoglycémie doit être authentifiée par une mesure d’une valeur basse au moment d’un malaise. Enfin, s’il s’agit bien d’une hypoglycémie, le malaise doit disparaître rapidement après resucrage. Une fois le diagnostic posé sur la base de cette triade, l’anamnèse doit faire préciser, outre la sévérité des malaises, leur chronologie, après les repas ou à jeun, ce qui oriente vers une hypoglycémie réactive, fonctionnelle, ou vers une hypoglycémie d’origine organique (insulinome). Des examens complémentaires, faisant d’abord appel à la biologie clinique, ensuite éventuellement à l’imagerie médicale, permettront de, non seulement confirmer le diagnostic d’hypoglycémie, mais aussi d’en préciser l’origine, ce qui orientera la stratégie thérapeutique. [less ▲]

Detailed reference viewed: 29 (11 ULg)
Full Text
Peer Reviewed
See detailSemantic Integration by Pattern Priming: Experiment and Cortical Network Model
Lavigne, Frédéric; Longrée, Dominique ULg; Mellet, Sylvie et al

in Cognitive Neurodynamics (2016), DOI 10.1007/s11571-016-9410-4

Detailed reference viewed: 15 (5 ULg)
Full Text
Peer Reviewed
See detailRelation entre hygiène bucco-dentaire et tendinopathies chez les sportifs
Kipgen, Laurence; Kaux, Jean-François ULg; Rompen, Eric ULg et al

in Science & Sports (2016), 31(4), 227-229

Detailed reference viewed: 48 (6 ULg)
Full Text
Peer Reviewed
See detailMacro-economic factors influencing the architectural business model shift in the pharmaceutical industry
Dierks, Raphaela Marie Louisa ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg et al

in Expert Review of Pharmacoeconomics & Outcomes Research (2016), First online

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its ... [more ▼]

Introduction: Technological innovations, new regulations, increasing costs of drug productions and new demands are only few key drivers of a projected alternation in the pharmaceutical industry and its underlying business model. Despite significant articles in the press, there is little medical and economic evidence on the rationale driving the transformation from the traditional Research & Development (R&D) model to new alternative business models, such as Mergers & Acquisitions (M&A). The purpose of this review is to understand the macro-economic factors responsible for the revolution of the pharmaceutical business model, by understanding the needs, desires, new behavioral patterns, but also challenges within the industry. Considering these changes will be the key to possessing a competitive advantage over the market players. Areas covered: Existing literature on new macro-economic factors changing the pharmaceutical landscape has been reviewed to present a clear image of the current market environment. Expert commentary: Literature and media sources show that pharmaceutical companies are facing an architectural alteration in their business model, with more M&A deals and collaborations headlining the papers. Although Q1 2016 did show a major slowdown in M&A deals by volume since 2013 (with deal cancellations of Pfizer and Allergan, or the downfall of Valeant) pharmaceutical analysts remain confident that this shortfall was a consequence of the equity market volatility. It seems likely that the shift to an M&A model will become apparent during the remainder of 2016, with deal announcements such as Abbott Laboratories, AbbVie and Sanofi worth USD 45billion [1] showing the appetite of big pharma companies to shift from the fully vertical integrated business model to more horizontal business models. [less ▲]

Detailed reference viewed: 63 (16 ULg)
Full Text
Peer Reviewed
See detailCooperative spontaneous emission from indistinguishable atoms in arbitrary motional quantum states
Damanet, François ULg; Braun, Daniel; Martin, John ULg

in Physical Review A (2016), 94

We investigate superradiance and subradiance of indistinguishable atoms with quantized motional states, starting with an initial total state that factorizes over the internal and external degrees of ... [more ▼]

We investigate superradiance and subradiance of indistinguishable atoms with quantized motional states, starting with an initial total state that factorizes over the internal and external degrees of freedom of the atoms. Due to the permutational symmetry of the motional state, the cooperative spontaneous emission, governed by a recently derived master equation [F. Damanet et al., Phys. Rev. A 93, 022124 (2016)], depends only on two decay rates γ and γ0 and a single parameter dd describing the dipole-dipole shifts. We solve the dynamics exactly for N = 2 atoms, numerically for up to 30 atoms, and obtain the large-N limit by a mean-field approach. We find that there is a critical difference γ0 − γ that depends on N beyond which superradiance is lost. We show that exact nontrivial dark states (i.e., states other than the ground state with vanishing spontaneous emission) only exist for γ = γ0 and that those states (dark when γ = γ0) are subradiant when γ < γ0. [less ▲]

Detailed reference viewed: 10 (4 ULg)
Full Text
Peer Reviewed
See detailLa responsabilité du supérieur hiérarchique devant la Cour pénale internationale : une première synthèse à la lumière du jugement prononcé dans l’affaire Bemba
Wery, Marine ULg; Deprez, Christophe ULg

in Revue de la Faculté de Droit de l'Université de Liège (2016), 2

Le 21 mars 2016, au terme d’une procédure longue de huit années, la Cour pénale internationale (CPI) prononça un verdict de culpabilité à l’encontre de Jean-Pierre Bemba. L’une des innovations majeures ... [more ▼]

Le 21 mars 2016, au terme d’une procédure longue de huit années, la Cour pénale internationale (CPI) prononça un verdict de culpabilité à l’encontre de Jean-Pierre Bemba. L’une des innovations majeures liées à cette affaire concerne le vecteur d’imputabilité mobilisé par les juges. Pour la première fois dans l’histoire de la CPI, une chambre de première instance s’est dégagée des modes traditionnels de responsabilité prévus à l’article 25 du Statut de Rome pour sceller le sort d’un accusé sur la base de l’article 28 du même instrument, en application duquel la responsabilité pénale d’un supérieur hiérarchique peut être mise en cause en lien avec les actes commis par ses subordonnés. Par cette contribution, nous proposons d’examiner le verdict du 21 mars 2016, mais aussi les quelques pistes jurisprudentielles préexistantes, afin d’ébaucher une première synthèse du mécanisme de responsabilité du supérieur hiérarchique devant la CPI. [less ▲]

Detailed reference viewed: 83 (10 ULg)
Full Text
See detailAlligator Records- 45è anniversaire-Interview Bruce Iglauer
Sacré, Robert ULg

in ABS Magazine (2016), (51), 8-17

Alligator Records (Chicago,IL.) 45 ans au service du Blues

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailCutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients
Jurczyszyn, A.; Olszewska-Szopa, M.; Hungria, V. et al

in Leukemia & Lymphoma (2016), 57(9 2071-6), 2071-6

Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical ... [more ▼]

Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical outcomes, immunohistochemistry and cytogenetic features, and relevant laboratory data on 53 biopsy-proven skin MM cases. The median time from MM diagnosis to skin involvement was 2 years. There appears to be an overrepresentation of immunoglobulin class A (IgA) and light chain disease in skin MM. We found no correlation between CD56 negative MM and skin infiltration. We found that skin MM patients presented in all MM stages (i.e. ISS stages I to III), and there was no preferential cytogenetic abnormality. Patients with skin MM carry a very poor prognosis with a median overall survival (OS) of 8.5 months as time from skin involvement. Moreover, patients with IgA disease and plasmablastic morphology appear to have a worse OS. [less ▲]

Detailed reference viewed: 26 (3 ULg)
Full Text
See detailDu processus aux soins intégrés: Expérience de gestion de projet bottom-up
ERPICUM, Marie ULg; BASSLEER, Bernard ULg; DEFRAIGNE, Jean ULg et al

in Gestions Hospitalieres (2016), 558(Août/septembre 2016),

Le service de chirurgie cardiaque du CHU de Liège a soutenu des recherches visant à développer un programme d’épargne sanguine, enjeu actuel de taille dans ce secteur des soins de santé. Ce projet a ... [more ▼]

Le service de chirurgie cardiaque du CHU de Liège a soutenu des recherches visant à développer un programme d’épargne sanguine, enjeu actuel de taille dans ce secteur des soins de santé. Ce projet a évolué vers la création d’un itinéraire clinique chirurgical cardiaque et d’un modèle institutionnel pour le développement d’autres itinéraires cliniques. Une évolution qui permet de déterminer les missions spécifiques de l’institution et ses objectifs stratégiques, et de s’associer aux projets nationaux. L’adhésion multidisciplinaire, soutenue par un leadership médical et infirmier, ainsi que la reconnaissance institutionnelle sont les déterminants de la pérennité de cette démarche bottom-up. [less ▲]

Detailed reference viewed: 31 (5 ULg)
Full Text
Peer Reviewed
See detailEtat de la contraception en 2016
Manigart, Yannick; BELIARD, Aude ULg; Rozenberg, Serge et al

in Revue Médicale de Bruxelles (2016), 37

Introduction: The Pill and and other forms of hormonal contraception, if taken correctly, are very effective and safe for millions of women, but since a few years, due to debates and controversies about ... [more ▼]

Introduction: The Pill and and other forms of hormonal contraception, if taken correctly, are very effective and safe for millions of women, but since a few years, due to debates and controversies about third- and fourth-generation pills, other options have gained in popularity. Objectives: to provide a review of oestroprogestative contraception (OP), progestative contraception, IUDs with a focus on their advantages and side-effects according to the specific needs of women.Methods: Literature review and lessons learned from clinical practice.Results: the importance of family and individual history, the life-style and socio-economic conditions are critical factors for advising women of the 15 contraceptive choices available to them. The risk/benefit ratio of OP contraception needs a yearly follow-up. The progestative contraception is the preferred option for women who have contraindication for estrogen, are older than forty, and/or have risk factors such as a history of venous thromboembolism, overweight and smoking. The IUD is well tolerated and causes few side effects. Among the other contraceptive methods, sterilization and diaphragms are briefly discussed. Conclusions: Among the many safe and effective contraceptive methods, it is important for general practitioners to know the advantages and the side effects of each method, as well as the specific conditions of the woman, to propose the best options available. In case of difficulties of follow up or adherence to daily uptake, in particular among adolescents, long-acting methods such as IUD or implants are preferable. [less ▲]

Detailed reference viewed: 48 (6 ULg)
Full Text
Peer Reviewed
See detailCrises et conflits au Moyen-Orient. Quels sont les impacts sur les relations entre la Turquie et l'Iran?
Bayramzadeh, Kamal ULg

in Revue Etudes internationales (2016), XLVII, N°2-3

Crises and Conflicts in the Middle East : What Impacts on Relations between Turkey and Iran? This article analyzes the security challenges of conflicts in the Middle East and their impact on Iranian ... [more ▼]

Crises and Conflicts in the Middle East : What Impacts on Relations between Turkey and Iran? This article analyzes the security challenges of conflicts in the Middle East and their impact on Iranian-Turkish relations, which are marked by differences over the issue of regional security based on divergent perceptions of national security, especially since the Syrian conflict. This study shows that shifting power relationships in the Middle East have created new security issues with political, military, economic and societal ramifications. On the one hand, the Middle East is facing a new form of struggle between regional powers—particularly Saudi Arabia, Iran and Turkey—and on the other, it is confronted with the activities of non-state actors involved in the war in Syria and Iraq. This new balance of power has created a security dilemma as the crises and conflicts in Iraq, Syria, and Yemen provoke a situation of chaos. [less ▲]

Detailed reference viewed: 27 (7 ULg)
Full Text
Peer Reviewed
See detailL’administration Obama, a t-elle (vraiment) navigué à vue sur la scène mondiale ?
Santander, Sébastian ULg

in Recherches internationales (2016), 106

Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous ... [more ▼]

Dès son arrivée au pouvoir, Obama a pris le soin de tenir un discours de rupture avec son prédécesseur dont l’action interventionniste et belliqueuse avait terni l’image des ÉU dans le monde. Il a sous-entendu qu’il ne se laisserait pas enfermer dans des cadres idéologiques et qu’il privilégierait une approche « pragmatique » et « souple », et fait savoir qu’il n’engagerait plus les ÉU dans des opérations militaires de grande envergure. Ce discours d’une approche au cas par cas combiné à la politique du retrait militaire d’Irak et d’Afghanistan, et au fait que Obama a parfois été amené à adopter une attitude réactive pour répondre aux soubresauts de l’actualité internationale ont alimenté la perception dominante selon laquelle cette administration se désintéressait et se désengageait du monde, et déployait une politique étrangère marquée par l’indécision, l’improvisation et l’absence de vision à long terme. On ne peut omettre que cette administration a parfois du adapter et ajuster sa politique en fonction des événements internationaux. Faut-il pour autant conclure que sous Obama la première puissance mondiale a navigué à vue sur la scène internationale ? [less ▲]

Detailed reference viewed: 148 (77 ULg)
Full Text
Peer Reviewed
See detailLa Paméla de Voltaire des Lumières au XXIe siècle - changements de statut et réception générique du texte
Daubercies, Laurence ULg

in Loxias : Littératures Française et Comparées (2016)

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailBiocompatibility of polymer-infiltrated-ceramic-network (PICN) materials with Human Gingival Fibroblasts (HGFs).
GRENADE, Charlotte ULg; De Pauw-Gillet, Marie-Claire ULg; Gailly, Patrick ULg et al

in Dental materials : official publication of the Academy of Dental Materials (2016), 32(9), 1152-1164

OBJECTIVES: Polymer-infiltrated-ceramic-network (PICN) materials constitute an innovative class of CAD-CAM materials offering promising perspectives in prosthodontics, but no data are available in the ... [more ▼]

OBJECTIVES: Polymer-infiltrated-ceramic-network (PICN) materials constitute an innovative class of CAD-CAM materials offering promising perspectives in prosthodontics, but no data are available in the literature regarding their biological properties. The objective of the present study was to evaluate the in vitro biocompatibility of PICNs with human gingival fibroblasts (HGFs) in comparison with materials typically used for implant prostheses and abutments. METHODS: HGF attachment, proliferation and spreading on discs made of PICN, grade V titanium (Ti), yttrium zirconia (Zi), lithium disilicate glass-ceramic (eM) and polytetrafluoroethylene (negative control), were evaluated using a specific insert-based culture system (IBS-R). Sample surface properties were characterized by XPS, contact angle measurement, profilometry and SEM. RESULTS: Ti and Zi gave the best results regarding HGF viability, morphology, number and coverage increase with time in comparison with the negative control, while PICN and eM gave intermediate results, cell spreading being comparable for PICN, Ti, Zi and eM. Despite the presence of polymers and their related hydrophobicity, PICN exhibited comparable results to glass-ceramic materials, which could be explained by the mode of polymerization of the monomers. SIGNIFICANCE: The results of the present study confirm that the currently employed materials, i.e. Ti and Zi, can be considered to be the gold standard of materials in terms of HGF behavior, while PICN gave intermediate results comparable to eM. The impact of the present in vitro results needs to be further investigated clinically, particularly in the view of the utilization of PICNs for prostheses on bone-level implants. [less ▲]

Detailed reference viewed: 67 (10 ULg)
Full Text
Peer Reviewed
See detailAlterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans
GLAUZY; PEFFAULT DE LATOUR; ANDRE-SCHMUTZ et al

in Experimental Hematology (2016), 44(9), 811-816

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailDetermination of iohexol and iothalamate in serum and urine by capillary electrophoresis.
Van Houcke, Sofie K.; Seaux, Liesbeth; Cavalier, Etienne ULg et al

in Electrophoresis (2016)

Estimation of glomerular filtration rate (eGFR) is essential to assess kidney function. Iodine containing contrast agents detection by HPLC has been proposed as a safe alternative for inulin or ... [more ▼]

Estimation of glomerular filtration rate (eGFR) is essential to assess kidney function. Iodine containing contrast agents detection by HPLC has been proposed as a safe alternative for inulin or radioactive compounds. However, HPLC is a time-consuming and labour-intensive method. The aim of this study was to develop an assay for iohexol and iothalamate using capillary electrophoresis (CE). Iohexol and iothalamate were directly analysed by CE in serum and urine, using photometric detection (246 nm). Serum peak height was proportional to iohexol and iothalamate concentrations. Detection limits for iohexol and iothalamate were 10 mg/L and 5 mg/L. Limits of quantification were 13.0 mg/L and 15.0 mg/L. Within-run CVs were 4.9% and 6.5%; between-run CVs 3.1-9.9% and 3.8-13.7%. A good correlation was observed between CE and HPLC: y = 1.1703 x + 5.017 (iohexol) and y = 0.7807 x + 11.01 (iothalamate) [y = concentration obtained by CE (mg/L), x = concentration obtained by HPLC (mg/L)]. In addition, CE allowed to determine urinary iohexol concentration. Although the detection limit for CE was higher than for HPLC, CE can still be used for eGFR determination. Advantages of this high throughput method are the absence of sample pretreatment and a minimal sample volume requirement. This article is protected by copyright. All rights reserved. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailLes usages des manuels dans les préparations des enseignants stagiaires
Scheepers, Caroline ULg

in Français Aujourd'Hui (Le) (2016), 194

La présente contribution se propose d’analyser la façon dont les manuels sont convoqués par les stagiaires dans leurs préparations de cours de français. Dès lors, la focalisation se place non sur les ... [more ▼]

La présente contribution se propose d’analyser la façon dont les manuels sont convoqués par les stagiaires dans leurs préparations de cours de français. Dès lors, la focalisation se place non sur les manuels en tant quel tels, mais sur leur réception et leur réinvestissement dans les pratiques des étudiants. Ont été analysées une centaine de fiches de préparation élaborées par de futurs enseignants belges, qu’ils se destinent à enseigner au primaire, au secondaire inférieur (collège) ou supérieur (lycée). Les usages du manuel révèlent et construisent des différences notables en terme de compétences enseignées, de gestes pédagogiques mobilisés, de rapport au savoir, de culture professionnelle, de formation… Étudier la réception et l’utilisation du manuel revient à problématiser des pratiques et des représentations fondamentales qui touchent à ce que veulent dire enseigner, (faire) apprendre ou construire une leçon. Cette recherche éclaire une facette du processus de planification des apprentissages. [less ▲]

Detailed reference viewed: 22 (3 ULg)
Full Text
Peer Reviewed
See detailInvasive and Non-invasive Electrical Pericranial Nerve Stimulation for the Treatment of Chronic Primary Headaches
D'Ostilio, Kevin ULg; MAGIS, Delphine ULg

in Current Pain and Headache Reports (2016), 20

Chronic primary headaches are widespread disorders which cause significant quality of life and socioprofessional impairment. Available pharmacological treatments have often a limited efficacy and/or can ... [more ▼]

Chronic primary headaches are widespread disorders which cause significant quality of life and socioprofessional impairment. Available pharmacological treatments have often a limited efficacy and/or can generate unbearable side effects. Electrical nerve stimulation is a well known non-destructive method of pain modulation which has been recently applied to headache management. In this review, we summarise recent advances in invasive and non-invasive neurostimulation techniques targeting pericranial structures for the treatment of chronic primary headaches, chiefly migraine and cluster headache: occipital nerve, supraorbital nerve, vagus nerve, and sphenopalatineganglion stimulations. Invasive neurostimulation therapies have offered a new hope to drug-refractory headache sufferers but are not riskless and should be proposed only to chronic patients who failed to respond to most existing preventives. Non-invasive neurostimulation devices are user-friendly, safe and well tolerated and are thus taking an increasing place in the multidisciplinary therapeutical armamentarium of primary headaches. [less ▲]

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailValidation of Prediction Models for Near Adult Height in Children with Idiopathic Growth Hormone Deficiency Treated with Growth Hormone A Belgian Registry Study
Straetemans, Saartje; De Schepper, Jean; THOMAS, Muriel et al

in Hormone Research in Paediatrics (2016), 86

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailGalileo Cycle-Slip Detection. How Four Frequencies Help When the Ionosphere Is Disturbed.
Van de Vyvere, Laura; Warnant, René ULg

in GPS World (2016), 27(9), 50-56

Detailed reference viewed: 27 (6 ULg)
Full Text
Peer Reviewed
See detailInteraction of Avibactam with Class B Metallo-β-Lactamases.
Abboud, MI; Damblon, Christian ULg; Brem, J et al

in Antimicrobial Agents and Chemotherapy (2016), 60

Detailed reference viewed: 15 (2 ULg)
Full Text
See detailA pas mesurés: l'architecture de MAAT ontwerpers
De Visscher, Lisa ULg

in A+ : Architecture in Belgium (2016), 261

MAAT architects is a young office, but their three partners have a year-long experience that enables them to work on big scale projects where their idea of society shimmers through. This article was ... [more ▼]

MAAT architects is a young office, but their three partners have a year-long experience that enables them to work on big scale projects where their idea of society shimmers through. This article was written in the frame of the ACROSS lecture series where MAAT Architects gave a lecture in November 2016. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailCircadian dynamics in measures of cortical excitation and inhibition balance
Chellappa, Sarah; Gaggioni, Giulia ULg; LY, Julien ULg et al

in Scientific Reports (2016), 6:33661

Detailed reference viewed: 27 (12 ULg)
Full Text
Peer Reviewed
See detailDu stilus à la plume ... du chapeau. Quelques réflexions sur la notion de style
Houbart, Claudine ULg

in Bruxelles Patrimoines (2016), (18),

Detailed reference viewed: 20 (5 ULg)
Full Text
Peer Reviewed
See detailA combined transmission spectrum of the Earth-sized exoplanets TRAPPIST-1 b and c
de Wit, Julien; Wakeford, Hannah R.; Gillon, Michaël ULg et al

in Nature (2016), 537

Three Earth-sized exoplanets were recently discovered close to the habitable zone of the nearby ultracool dwarf star TRAPPIST-1 (ref. 3). The nature of these planets has yet to be determined, as their ... [more ▼]

Three Earth-sized exoplanets were recently discovered close to the habitable zone of the nearby ultracool dwarf star TRAPPIST-1 (ref. 3). The nature of these planets has yet to be determined, as their masses remain unmeasured and no observational constraint is available for the planetary population surrounding ultracool dwarfs, of which the TRAPPIST-1 planets are the first transiting example. Theoretical predictions span the entire atmospheric range, from depleted to extended hydrogen-dominated atmospheres. Here we report observations of the combined transmission spectrum of the two inner planets during their simultaneous transits on 4 May 2016. The lack of features in the combined spectrum rules out cloud-free hydrogen-dominated atmospheres for each planet at ≥10σ levels; TRAPPIST-1 b and c are therefore unlikely to have an extended gas envelope as they occupy a region of parameter space in which high-altitude cloud/haze formation is not expected to be significant for hydrogen-dominated atmospheres. Many denser atmospheres remain consistent with the featureless transmission spectrum—from a cloud-free water-vapour atmosphere to a Venus-like one. [less ▲]

Detailed reference viewed: 62 (9 ULg)
Full Text
Peer Reviewed
See detail"Je te porte dans moi comme un oiseau blessé" (Louis Aragon)
Melice, Anne ULg

in Centre Franco Basaglia, Mouvement pour une psychiatrie démocratique dans le milieu de vie (2016)

Dans le sillage du texte précédent « Oiseaux blessés. Avec les stagiaires d’Article 23 », ce texte-ci rend compte des spécificités de l’hospitalité que j’ai observées. Ces spécificités s’éclairent à mes ... [more ▼]

Dans le sillage du texte précédent « Oiseaux blessés. Avec les stagiaires d’Article 23 », ce texte-ci rend compte des spécificités de l’hospitalité que j’ai observées. Ces spécificités s’éclairent à mes yeux des problématiques du don et du contre-don, du « care », des relations à plaisanterie. Enfin, le respect des singularités et des limites individuelles, ainsi que la mise en suspens des rapports concurrentiels constitutifs du monde de travail, dessinent un espace alternatif à l’égard de ce dernier. [less ▲]

Detailed reference viewed: 70 (2 ULg)
Full Text
Peer Reviewed
See detailEffect of citrate anticoagulation on CO2 extraction during low flow extracorporeal veno-venous CO2 removal therapy
MORIMONT, Philippe ULg; Habran, Simon ULg; Hubert, Romain et al

in Intensive Care Medicine Experimental (2016), 4

Detailed reference viewed: 29 (5 ULg)
Full Text
Peer Reviewed
See detailThe influence of England on the first English gardens in the Southern Low Countries and the Principality of Liege
De Harlez De Deulin, Nathalie ULg

in Garden History (2016), 44(Automn), 87-100

The English Garden appearead in the Low Countries quite late in the 18th century since the geometric model – mainly influenced by the French style diffused by the treatise of Dezallier d’Argenville – is ... [more ▼]

The English Garden appearead in the Low Countries quite late in the 18th century since the geometric model – mainly influenced by the French style diffused by the treatise of Dezallier d’Argenville – is still in fashion in the years 1760. Amongst the famous realizations of the time figure the Garden of Leeuwergem Castle (1762), the upper Garden of Freÿr Castle (c. 1775) or the Royal Park of Brussels (1786). The two following decades (1760-1780) correspond to the major development of the new irregular style in the Low Countries merely influenced by Picturesque Garden but also by Naturalistic style Garden discovered by members of the aristocracy travelling in Great Britain as well as some gardeners sent to England to be trained and to learn how to grow new exotic plants. This paper deals with the major designers and the most famous sleeping partners engaged in the program of creation of the first English gardens in the country, notably Prince Charles-Joseph de Ligne (Beloeil and Baudour), Duke Emmanuel de Croÿ (Hermitage), Count of Seneffe Joseph Depestre (Seneffe), Duke Emmanuel d’Hane Steenhuyse (Leeuwergem) and, first of all, Duke Albert de Saxe-Teschen and the Archduchess Marie Christine who asked Lancelot Brown a plan for the site near Brussels called the Fine Mountain (Schoonenberg). Brown has sent his project from Britain in July 1782. We have also taken interest in the many unknown owners who gathered important plants collection that are only described in travel diaries or mentioned in archives (inventories and other lists of purchase or supply) that have no longer survived. This article present some facets of the global research accomplished in the thesis (2015) focusing on the direct influence of the English design on the first irregular gardens in the Southern Low Countries. [less ▲]

Detailed reference viewed: 12 (1 ULg)
Full Text
See detailDésenchanter le cinéma ? Autour de "Blanche-Neige Lucie" de Pierre Huyghe
Tomasovic, Dick ULg

in Mondes du cinéma (2016), 09

Etude des enjeux esthétiques et idéologiques du film "Blanche-Neige Lucie" de Pierre Huyghes.

Detailed reference viewed: 46 (27 ULg)
Full Text
See detailMethodik zur schnellen Bewertung von Syntheserouten auf Basis von Exergiebilanzen
Frenzel, Philipp; Pfennig, Andreas ULg

in Chemie Ingenieur Technik (2016), 88(9), 1381

Heutige chemische Produkte basieren fast ausschließlich auf erdölbasierten Rohstoffen. Aufgrund weltweiter Bemühungen, die Abhängigkeit von fossilen Rohstoffen zu reduzieren, wird in den letzten Jahren ... [more ▼]

Heutige chemische Produkte basieren fast ausschließlich auf erdölbasierten Rohstoffen. Aufgrund weltweiter Bemühungen, die Abhängigkeit von fossilen Rohstoffen zu reduzieren, wird in den letzten Jahren verstärkt die Nutzung alternativer Kohlenstoffquellen wie Biomasse oder CO2 erforscht. Die alternativen Kohlenstoffquellen unterscheiden sich hinsichtlich ihrer Zusammensetzung und Stoffeigenschaften teilweise deutlich von fossilen Rohstoffen. Aus diesem Grund müssen Syntheserouten und darauf aufbauende Prozesse neu entwickelt werden. Da zum einen sehr viele Syntheserouten prinzipiell denkbar sind und zum anderen die Entwicklung der entsprechenden Prozesse aufwendig ist, wird eine Möglichkeit benötigt, begrenzte Entwicklungsressourcen sinnvoll zu steuern. Dazu sollte bereits in einem frühen Entwicklungsstadium ein quantitativer Vergleich der Syntheserouten erfolgen, um diejenigen zu identifizieren, die das größte wirtschaftliche Potential versprechen. In diesem Vortrag wird eine Methodik vorgestellt, um eine schnelle erste, auf Exergie basierte Bewertung des wirtschaftlichen Potentials einer Syntheseroute bereits in einem frühen Entwicklungsstadium durchzuführen, in dem nur wenige Informationen vorliegen. Die Idee der Methodik ist, Syntheserouten in standardisierten Prozessen abzubilden, wodurch eine automatisierte Auswertung und somit ein schnelles Screening möglich wird. Die standardisierten Prozesse umfassen sowohl den Einfluss der Reaktion durch Abbildung der Reaktionsbedingungen, Stöchiometrie, Umsatz und Selektivität als auch die Auswirkungen der Trennaufgabe. Ebenso berücksichtigt wird die Rückführung von Lösungsmitteln und ggf. nicht umgesetzten Edukten. Als zentrale Bewertungsgröße zur Abschätzung des wirtschaftlichen Potentials wird eine Kombination aus Exergie- und Rohstoffeinsatz herangezogen. Der Vorteil von Exergiebilanzen gegenüber Energiebilanzen ist, dass die Produktion von Entropie berücksichtigt wird und so die Auswirkungen einzelner Prozessschritte untersucht und zwischen verschiedenen Energieformen unterschieden werden kann. Durch Berechnung der Exergieverluste, also der Verluste von Exergie aufgrund von Entropieerzeugung in den Prozessen, ergibt sich ein quantitativer Vergleich verschiedener Syntheserouten. [less ▲]

Detailed reference viewed: 38 (5 ULg)
Full Text
See detailUsing a structural root system model for an in-depth assessment of root image analysis pipeline
Lobet, Guillaume ULg; Koevoets, Iko; Tocquin, Pierre ULg et al

in bioRxiv (2016)

Root system analysis is a complex task, often performed using fully automated image analysis pipelines. However, these pipelines are usually evaluated with a limited number of ground-truth root images ... [more ▼]

Root system analysis is a complex task, often performed using fully automated image analysis pipelines. However, these pipelines are usually evaluated with a limited number of ground-truth root images, most likely of limited size and complexity. We have used a root model, ArchiSimple to create a large and diverse library of ground-truth root system images (10.000). This library was used to evaluate the accuracy and usefulness of several image descriptors classicaly used in root image analysis pipelines. Our analysis highlighted that the accuracy of the different metrics is strongly linked to the type of root system analyzed (e.g. dicot or monocot) as well as their size and complexity. Metrics that have been shown to be accurate for small dicot root systems might fail for large dicots root systems or small monocot root systems. Our study also demonstrated that the usefulness of the different metrics when trying to discriminate genotypes or experimental conditions may vary. Overall, our analysis is a call to caution when automatically analyzing root images. If a thorough calibration is not performed on the dataset of interest, unexpected errors might arise, especially for large and complex root images. To facilitate such calibration, both the image library and the different codes used in the study have been made available to the community. [less ▲]

Detailed reference viewed: 34 (3 ULg)
Full Text
See detailLes Nouveaux Liégeois. Migrations et Transformations Urbaines
Lafleur, Jean-Michel ULg; Stangherlin, Gregor

in Dérivations (2016), (3), 194-203

Dans cet article, nous proposons de discuter la migration contemporaine sur le territoire de la Ville de Liège. Cette discussion repose pour l’essentiel sur une analyse des données statistiques ... [more ▼]

Dans cet article, nous proposons de discuter la migration contemporaine sur le territoire de la Ville de Liège. Cette discussion repose pour l’essentiel sur une analyse des données statistiques disponibles et une revue de la littérature scientifique produite sur les migrations à Liège ces dernières années. Nous commençons donc par une description des grandes évolutions démographiques sur le territoire de la ville depuis 1991 pour insister ensuite sur les effets de la migration dans cinq quartiers de la ville. Cette première partie souligne le rôle essentiel que joue la migration dans la croissance démographique observée ces dix dernières années à Liège. Ensuite, nous examinons la présence étrangère sur le territoire de la ville selon les 5 dimensions fréquemment citées dans les débats sur l’intégration des populations étrangères : emploi, logement, éducation, socio-culturelle et politique. [less ▲]

Detailed reference viewed: 404 (25 ULg)
Full Text
Peer Reviewed
See detailOxytocin in survivors of childhood-onset craniopharyngioma
Daubenbüchel, Anna; Hoffmann, Anika; Eveslage, Maria et al

in Endocrine (2016)

Quality of survival of childhood-onset cranio- pharyngioma patients is frequently impaired by hypotha- lamic involvement or surgical lesions sequelae such as obesity and neuropsychological deficits ... [more ▼]

Quality of survival of childhood-onset cranio- pharyngioma patients is frequently impaired by hypotha- lamic involvement or surgical lesions sequelae such as obesity and neuropsychological deficits. Oxytocin, a pep- tide hormone produced in the hypothalamus and secreted by posterior pituitary gland, plays a major role in regula- tion of behavior and body composition. In a cross- sectional study, oxytocin saliva concentrations were ana- lyzed in 34 long-term craniopharyngioma survivors with and without hypothalamic involvement or treatment- related damage, recruited in the German Childhood Cra- niopharyngioma Registry, and in 73 healthy controls, attending the Craniopharyngioma Support Group Meeting 2014. Oxytocin was measured in saliva of craniophar- yngioma patients and controls before and after standar- dized breakfast and associations with gender, body mass index, hypothalamic involvement, diabetes insipidus, and irradiation were analyzed. Patients with preoperative hypothalamic involvement showed similar oxytocin levels compared to patients without hypothalamic involvement and controls. However, patients with surgical hypotha- lamic lesions grade 1 (anterior hypothalamic area) pre- sented with lower levels (p = 0.017) of oxytocin under fasting condition compared to patients with surgical lesion of posterior hypothalamic areas (grade 2) and patients without hypothalamic lesions (grade 0). Craniophar- yngioma patients’ changes in oxytocin levels before and after breakfast correlated (p = 0.02) with their body mass index. Craniopharyngioma patients continue to secrete oxytocin, especially when anterior hypothalamic areas are not involved or damaged, but oxytocin shows less varia- tion due to nutrition. Oxytocin supplementation should be explored as a therapeutic option in craniopharyngioma patients with hypothalamic obesity and/or behavioral pathologies due to lesions of specific anterior hypotha- lamic areas. Clinical trial number: KRANIOPHAR- YNGEOM 2000/2007(NCT00258453; NCT01272622). [less ▲]

Detailed reference viewed: 32 (2 ULg)
Full Text
Peer Reviewed
See detailFire Performance of Columns made of Normal and High Strength Concrete: A Comparative Analysis
Gernay, Thomas ULg

in Key Engineering Materials (2016), 711

The use of high strength concrete (HSC) in multi-story buildings has become increasingly popular. Selection of HSC over normal strength concrete (NSC) allows for reducing the dimensions of the columns ... [more ▼]

The use of high strength concrete (HSC) in multi-story buildings has become increasingly popular. Selection of HSC over normal strength concrete (NSC) allows for reducing the dimensions of the columns sections. However, this reduction has consequences on the structural performance in case of fire, as smaller cross sections lead to faster temperature increase in the section core. Besides, HSC experiences higher rates of strength loss with temperature and a higher susceptibility to spalling than NSC. The fire performance of a column can thus be affected by selecting HSC over NSC. This research performs a comparison of the fire performance of HSC and NSC columns, based on numerical simulations by finite element method. The thermal and structural analyses of the columns are conducted with the software SAFIR®. The variation of concrete strength with temperature for the different concrete classes is adopted from Eurocode. Different configurations are compared, including columns with the same load bearing capacity and columns with the same cross section. The relative loss of load bearing capacity during the fire is found to be more pronounced for HSC columns than for NSC columns. The impact on fire resistance rating is discussed. These results suggest that consideration of fire loading limits the opportunities for use of HSC, especially when the objective is to reduce the dimensions of the columns sections. [less ▲]

Detailed reference viewed: 34 (12 ULg)
Full Text
Peer Reviewed
See detailThe Case : Acute renal failure and refractory hyponatremia
denis, Chloé; JADOT, Virginie ULg; BOUQUEGNEAU, Antoine ULg et al

in Kidney International (2016), 90

Detailed reference viewed: 28 (10 ULg)