Conclusions: TIGRE is obviously able to detect stellar rotation periods in the CaII H+K emission cores when the time series contains a sufficient number of data points. However, this is frequently not achievable during the wet summer season in Guanajuato. Hence, future estimates of rotation periods will concentrate on stars that are observable during the winter season from October until April. [less ▲]Detailed reference viewed: 25 (2 ULg) Fe XXV line profiles in colliding wind binariesRauw, Grégor ; Mossoux, Enmanuelle; Nazé, Yaël in New Astronomy (2016), 43Strong wind-wind collisions in massive binaries generate a very hot plasma that frequently produces a moderately strong iron line. The morphology of this line depends upon the properties of the wind ... [more ▼]Strong wind-wind collisions in massive binaries generate a very hot plasma that frequently produces a moderately strong iron line. The morphology of this line depends upon the properties of the wind interaction zone and its orientation with respect to the line of sight. As the binary components revolve around their common centre of mass, the line profiles are thus expected to vary. With the advent of the next generation of X-ray observatories (Astro-H, Athena) that will offer high-resolution spectroscopy above 6 keV, it will become possible to exploit these changes as the most sensitive probe of the inner parts of the colliding wind interaction. Using a simple prescription of the wind-wind interaction in an early-type binary, we have generated synthetic line profiles for a number of configurations and orbital phases. These profiles can help constrain the properties of the stellar winds in such binary systems. [less ▲]Detailed reference viewed: 49 (3 ULg) The LEECH Exoplanet Imaging Survey: Characterization of the Coldest Directly Imaged Exoplanet, GJ 504 b, and Evidence for Superstellar MetallicitySkemer, Andrew J.; Morley, Caroline V.; Zimmerman, Neil T. et alin Astrophysical Journal (2016), 817As gas giant planets and brown dwarfs radiate away the residual heat from their formation, they cool through a spectral type transition from L to T, which encompasses the dissipation of cloud opacity and ... [more ▼]As gas giant planets and brown dwarfs radiate away the residual heat from their formation, they cool through a spectral type transition from L to T, which encompasses the dissipation of cloud opacity and the appearance of strong methane absorption. While there are hundreds of known T-type brown dwarfs, the first generation of directly imaged exoplanets were all L type. Recently, Kuzuhara et al. announced the discovery of GJ 504 b, the first T dwarf exoplanet. GJ 504 b provides a unique opportunity to study the atmosphere of a new type of exoplanet with a ˜500 K temperature that bridges the gap between the first directly imaged planets (˜1000 K) and our own solar system's Jupiter (˜130 K). We observed GJ 504 b in three narrow L-band filters (3.71, 3.88, and 4.00 μm), spanning the red end of the broad methane fundamental absorption feature (3.3 μm) as part of the LBTI Exozodi Exoplanet Common Hunt (LEECH) exoplanet imaging survey. By comparing our new photometry and literature photometry with a grid of custom model atmospheres, we were able to fit GJ 504 b's unusual spectral energy distribution for the first time. We find that GJ 504 b is well fit by models with the following parameters: T[SUB]eff[/SUB] = 544 ± 10 K, g < 600 m s[SUP]-2[/SUP], [M/H] = 0.60 ± 0.12, cloud opacity parameter of f[SUB]sed[/SUB] = 2-5, R = 0.96 ± 0.07 R[SUB]Jup[/SUB], and log(L) = -6.13 ± 0.03 L[SUB]⊙[/SUB], implying a hot start mass of 3-30 M[SUB]jup[/SUB] for a conservative age range of 0.1-6.5 Gyr. Of particular interest, our model fits suggest that GJ 504 b has a superstellar metallicity. Since planet formation can create objects with nonstellar metallicities, while binary star formation cannot, this result suggests that GJ 504 b formed like a planet, not like a binary companion. The LBT is an international collaboration among institutions in the United States, Italy, and Germany. LBT Corporation partners are the University of Arizona on behalf of the Arizona university system; Istituto Nazionale di Astrophisica, Italy; LBT Beteiligungsgesellschaft, Germany, representing the Max-Planck Society, the Astrophysical Institute Potsdam, and Heidelberg University; The Ohio State University, and the Research Corporation, on behalf of the University of Notre Dame, University of Minnesota, and University of Virginia. [less ▲]Detailed reference viewed: 31 (3 ULg) The MiMeS survey of magnetism in massive stars: introduction and overviewWade, G. A.; Neiner, C.; Alecian, E. et alin Monthly Notices of the Royal Astronomical Society (2016), 456The MiMeS (Magnetism in Massive Stars) project is a large-scale, high-resolution, sensitive spectropolarimetric investigation of the magnetic properties of O- and early B-type stars. Initiated in 2008 and ... [more ▼]The MiMeS (Magnetism in Massive Stars) project is a large-scale, high-resolution, sensitive spectropolarimetric investigation of the magnetic properties of O- and early B-type stars. Initiated in 2008 and completed in 2013, the project was supported by three Large Program allocations, as well as various programmes initiated by independent principal investigators, and archival resources. Ultimately, over 4800 circularly polarized spectra of 560 O and B stars were collected with the instruments ESPaDOnS (Echelle SpectroPolarimetric Device for the Observation of Stars) at the Canada-France-Hawaii Telescope, Narval at the Télescope Bernard Lyot and HARPSpol at the European Southern Observatory La Silla 3.6 m telescope, making MiMeS by far the largest systematic investigation of massive star magnetism ever undertaken. In this paper, the first in a series reporting the general results of the survey, we introduce the scientific motivation and goals, describe the sample of targets, review the instrumentation and observational techniques used, explain the exposure time calculation designed to provide sensitivity to surface dipole fields above approximately 100 G, discuss the polarimetric performance, stability and uncertainty of the instrumentation, and summarize the previous and forthcoming publications. [less ▲]Detailed reference viewed: 38 (9 ULg) New and updated convex shape models of asteroids based on optical data from a large collaboration networkHanuš, J.; Ďurech, J.; Oszkiewicz, D. A. et alin Astronomy & Astrophysics (2016), 586Asteroid modeling efforts in the last decade resulted in a comprehensive dataset of almost 400 convex shape models and their rotation states. This amount already provided a deep insight into physical ... [more ▼]Asteroid modeling efforts in the last decade resulted in a comprehensive dataset of almost 400 convex shape models and their rotation states. This amount already provided a deep insight into physical properties of main-belt asteroids or large collisional families. We aim to increase the number of asteroid shape models and rotation states. Such results are an important input for various further studies such as analysis of asteroid physical properties in different populations, including smaller collisional families, thermophysical modeling, and scaling shape models by disk-resolved images, or stellar occultation data. This provides, in combination with known masses, bulk density estimates, but constrains also theoretical collisional and evolutional models of the Solar System. We use all available disk-integrated optical data (i.e., classical dense-in-time photometry obtained from public databases and through a large collaboration network as well as sparse-in-time individual measurements from a few sky surveys) as an input for the convex inversion method, and derive 3D shape models of asteroids, together with their rotation periods and orientations of rotation axes. The key ingredient is the support of more that one hundred observers who submit their optical data to publicly available databases. We present updated shape models for 36 asteroids, for which mass estimates are currently available in the literature or their masses will be most likely determined from their gravitational influence on smaller bodies, which orbital deflection will be observed by the ESA Gaia astrometric mission. This was achieved by using additional optical data from recent apparitions for the shape optimization. Moreover, we also present new shape model determinations for 250 asteroids, including 13 Hungarias and 3 near-Earth asteroids. [less ▲]Detailed reference viewed: 40 (9 ULg) Hot Jupiters with relatives: discovery of additional planets in orbit around WASP-41 and WASP-47Neveu-VanMalle, M.; Queloz, D.; Anderson, D. R. et alin Astronomy and Astrophysics (2016), 586We report the discovery of two additional planetary companions to WASP-41 and WASP-47. WASP-41 c is a planet of minimum mass 3.18 $\pm$ 0.20 M$_{\rm Jup}$ and eccentricity 0.29 $\pm$ 0.02, and it orbits ... [more ▼]We report the discovery of two additional planetary companions to WASP-41 and WASP-47. WASP-41 c is a planet of minimum mass 3.18 $\pm$ 0.20 M$_{\rm Jup}$ and eccentricity 0.29 $\pm$ 0.02, and it orbits in 421 $\pm$ 2 days. WASP-47 c is a planet of minimum mass 1.24 $\pm$ 0.22 M$_{\rm Jup}$ and eccentricity 0.13 $\pm$ 0.10, and it orbits in 572 $\pm$ 7 days. Unlike most of the planetary systems that include a hot Jupiter, these two systems with a hot Jupiter have a long-period planet located at only $\sim$1 au from their host star. WASP-41 is a rather young star known to be chromospherically active. To differentiate its magnetic cycle from the radial velocity effect induced by the second planet, we used the emission in the H$\alpha$ line and find this indicator well suited to detecting the stellar activity pattern and the magnetic cycle. The analysis of the Rossiter-McLaughlin effect induced by WASP-41 b suggests that the planet could be misaligned, though an aligned orbit cannot be excluded. WASP-47 has recently been found to host two additional transiting super Earths. With such an unprecedented architecture, the WASP-47 system will be very important for understanding planetary migration. [less ▲]Detailed reference viewed: 56 (4 ULg) Lens galaxies in the Illustris simulation: power-law models and the bias of the Hubble constant from time delaysXu, Dandan; Sluse, Dominique ; Schneider, Peter et alin Monthly Notices of the Royal Astronomical Society (2016), 456A power-law density model, i.e. ρ (r) ∝ r^{-γ ^' }}, has been commonly employed in strong gravitational lensing studies, including the so-called time-delay technique used to infer the Hubble constant H ... [more ▼]A power-law density model, i.e. ρ (r) ∝ r^{-γ ^' }}, has been commonly employed in strong gravitational lensing studies, including the so-called time-delay technique used to infer the Hubble constant H[SUB]0[/SUB]. However, since the radial scale at which strong lensing features are formed corresponds to the transition from the dominance of baryonic matter to dark matter, there is no known reason why galaxies should follow a power law in density. The assumption of a power law artificially breaks the mass-sheet degeneracy, a well-known invariance transformation in gravitational lensing which affects the product of Hubble constant and time delay and can therefore cause a bias in the determination of H[SUB]0[/SUB] from the time-delay technique. In this paper, we use the Illustris hydrodynamical simulations to estimate the amplitude of this bias, and to understand how it is related to observational properties of galaxies. Investigating a large sample of Illustris galaxies that have velocity dispersion σ[SUB]SIE[/SUB] ≥ 160 km s[SUP]-1[/SUP] at redshifts below z = 1, we find that the bias on H[SUB]0[/SUB] introduced by the power-law assumption can reach 20-50 per cent, with a scatter of 10-30 per cent (rms). However, we find that by selecting galaxies with an inferred power-law model slope close to isothermal, it is possible to reduce the bias on H[SUB]0[/SUB] to ≲ 5 per cent and the scatter to ≲ 10 per cent. This could potentially be used to form less biased statistical samples for H[SUB]0[/SUB] measurements in the upcoming large survey era. [less ▲]Detailed reference viewed: 21 (2 ULg) Two Small Temperate Planets Transiting Nearby M Dwarfs in K2 Campaigns 0 and 1Schlieder, Joshua E.; Crossfield, Ian J. M.; Petigura, Erik A. et alin Astrophysical Journal (2016), 818The prime Kepler mission revealed that small planets (<4 {R}[SUB]\oplus [/SUB]) are common, especially around low-mass M dwarfs. K2, the repurposed Kepler mission, continues this exploration of small ... [more ▼]The prime Kepler mission revealed that small planets (<4 {R}[SUB]\oplus [/SUB]) are common, especially around low-mass M dwarfs. K2, the repurposed Kepler mission, continues this exploration of small planets around small stars. Here we combine K2 photometry with spectroscopy, adaptive optics imaging, and archival survey images to analyze two small planets orbiting the nearby field-age M dwarfs, K2-26 (EPIC 202083828) and K2-9. K2-26 is an {{M}}1.0+/- 0.5 dwarf at 93 ± 7 pc from K2 Campaign 0. We validate its planet with a day period of 14.5665 and estimate a radius of {2.67}[SUB]-0.42[/SUB][SUP]+0.46[/SUP] {R}[SUB]\oplus [/SUB]. K2-9 is an {{M}}2.5+/- 0.5 dwarf at 110 ± 12 pc from K2 Campaign 1. K2-9b was first identified by Montet et al.; here we present spectra and adaptive optics imaging of the host star and independently validate and characterize the planet. Our analyses indicate K2-9b is a {2.25}[SUB]-0.96[/SUB][SUP]+0.53[/SUP] {R}[SUB]\oplus [/SUB] planet with a 18.4498 day period. K2-26b exhibits a transit duration that is too long to be consistent with a circular orbit given its measured stellar radius. Thus, the long transits are likely due to the photoeccentric effect and our transit fits hint at an eccentric orbit. Both planets receive low incident flux from their host stars and have estimated equilibrium temperatures <500 K. K2-9b may receive approximately Earth-like insolation. However, its host star exhibits strong GALEX UV emission which could affect any atmosphere it harbors. K2-26b and K2-9b are representatives of a poorly studied class of small planets with cool temperatures that have radii intermediate to Earth and Neptune. Future study of these systems can provide key insight into trends in bulk composition and atmospheric properties at the transition from silicate dominated to volatile rich bodies. Based on observations collected at the European Organization for Astronomical Research in the Southern Hemisphere, La Silla Observatory, Chile during program ID 194.C-0443. [less ▲]Detailed reference viewed: 20 (3 ULg) Diversity and ecology survey of mosquitoes potential vectors in Belgian equestrian farms: A threat prevention of mosquito-borne equine arbovirusesBoukraa, Slimane ; de la Grandière, Maria Ana ; Bawin, Thomas et alin Preventive Veterinary Medicine (2016), 124Emergence of West Nile Virus was recently recorded in several European countries, which can lead to severe health problems in horse populations. Europe is also at risk of introduction of mosquito-borne ... [more ▼]Emergence of West Nile Virus was recently recorded in several European countries, which can lead to severe health problems in horse populations. Europe is also at risk of introduction of mosquito-borne equine alphavirus from Americas. Prevention of these arboviruses requires a clear understanding of transmission cycles, especially their vectors. To characterize mosquito fauna, their ecology and identify potential vectors of equine arboviruses in Belgium, entomological surveys of six equestrian farms located in the Wolloon Region were conducted during 2011–2012. The harvest of mosquitoes was based on larval sampling (272 samples from 111 breeding sites) and monthly adults trapping (CO2-baited traps, Mosquito Magnet Liberty Plus). Among 51,493 larvae and 319 adult mosquitoes collected, morphological identification showed the presence of 11 species: Anopheles claviger (Meigen), An. maculipennis s.l. (Meigen), An. plumbeus (Stephens), Culex hortensis (Ficalbi), Cx. territans (Walker), Cx. pipiens s.l. L., Cx. torrentium (Martini), Coquillettidia richiardii (Ficalbi), Culiseta annulata (Schrank), Aedes cantans (Meigen), Ae. geniculatus (Olivier). Molecular identification of Cx. pipiens species complex allowed the detection of three molecular forms, Pipiens (92.3%), Molestus (4.6%) and Hybrid (3.1%). Larvae of Cx. pipiens sl and Cx. torrentium were omnipresent and the most abundant species. Water troughs, ponds and slurry (liquid manure) were the most favorable breeding sites of mosquito larvae. Based upon behavior and ecology of the identified mosquito species, Studied Belgian equestrian farms seem to provide a suitable environment and breeding sites for the proliferation of potential vectors of arboviruses and those being a real nuisance problem for horses and neighboring inhabitants. [less ▲]Detailed reference viewed: 53 (12 ULg) Decreased antibiotic consumption in the Belgian community: Is it credible?FRIPPIAT, Frédéric ; VERCHEVAL, Christelle ; LAYIOS, Nathalie in Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America (2016), 62(3), 403-404Detailed reference viewed: 37 (6 ULg) SHANNA WATERSTOWN La tornade noire venue de FlorideSacré, Robert in ABS Magazine (2016), (49), Interview de la chanteuse noire américaine Shanna Waterstown ; son histoire et son parcours artistiqueDetailed reference viewed: 25 (1 ULg) Mesh Management Methods in Finite Element Simulations of Orthodontic Tooth MovementMengoni, Marlène ; Ponthot, Jean-Philippe ; Boman, Romain in Medical Engineering & Physics (2016), 38(2), 140-147In finite element simulations of orthodontic tooth movement, one of the challenges is to represent long term tooth movement. Large deformation of the periodontal ligament and large tooth displacment due ... [more ▼]In finite element simulations of orthodontic tooth movement, one of the challenges is to represent long term tooth movement. Large deformation of the periodontal ligament and large tooth displacment due to bone remodelling lead to large distortions of the finite element mesh when a Lagrangian formalism is used. We propose in this work to use an Arbitrary Lagrangian Eulerian (ALE) formalism to delay remeshing operations. A large tooth displacement is obtained including effect of remodelling without the need of remeshing steps but keeping a good-quality mesh. Very large deformations in soft tissues such as the periodontal ligament is obtained using a combination of the ALE formalism used continuously and a remeshing algorithm used when needed. This work demonstrates that the ALE formalism is a very efficient way to delay remeshing operations. [less ▲]Detailed reference viewed: 83 (22 ULg) Diacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEOPavelka, Karel; Bruyère, Olivier ; Cooper, Cyrus et alin Drugs & Aging (2016), 33(2), 75-85Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) with anti-inflammatory, anti-catabolic and pro-anabolic properties on cartilage and synovial membrane. It has also recently been ... [more ▼]Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) with anti-inflammatory, anti-catabolic and pro-anabolic properties on cartilage and synovial membrane. It has also recently been shown to have protective effects against subchondral bone remodelling. Following the end of the revision procedure by the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency, the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) constituted a panel of 11 experts to better define the real place of diacerein in the armamentarium for treating OA. Based on a literature review of clinical trials and meta-analyses, the ESCEO confirms that the efficacy of diacerein is similar to that of non-steroidal anti-inflammatory drugs (NSAIDs) after the first month of treatment, and superior to that of paracetamol. Additionally, diacerein has shown a prolonged effect on symptoms of several months once treatment was stopped. The use of diacerein is associated with common gastrointestinal disorders such as soft stools and diarrhoea, common mild skin reactions, and, uncommonly, hepatobiliary disorders. However, NSAIDs and paracetamol are known to cause potentially severe hepatic, gastrointestinal, renal, cutaneous and cardiovascular reactions. Therefore, the ESCEO concludes that the benefit–risk balance of diacerein remains positive in the symptomatic treatment of hip and knee osteoarthritis. Furthermore, similarly to other SYSADOAs, the ESCEO positions diacerein as a first-line pharmacological background treatment of osteoarthritis, particularly for patients in whom NSAIDs or paracetamol are contraindicated [less ▲]Detailed reference viewed: 28 (10 ULg) Residual tumor micro-foci and overwhelming regulatory T lymphocyte infiltration are the causes of bladder cancer recurrence.Parodi, Alessia; Traverso, Paolo; Kalli, Francesca et alin Oncotarget (2016), 7(6), 6424-6435Bladder cancer has an unexplained, high recurrence rate. Causes of recurrence might include the presence of sporadic tumor micro-foci in the residual urothelial tissue after surgery associated with an ... [more ▼]Bladder cancer has an unexplained, high recurrence rate. Causes of recurrence might include the presence of sporadic tumor micro-foci in the residual urothelial tissue after surgery associated with an inverted ratio between intratumoral effector and regulatory T cell subsets. Hence, surgical specimens of both tumors and autologous, macroscopically/histologically free-of-tumor tissues were collected from 28 and 20 patients affected by bladder or renal cancer, respectively. The frequencies of effector (IFNγ+ and IL17+ T cells) and regulatory (CD4+CD25hiCD127lo and CD8+CD28-CD127loCD39+ Treg) T cell subpopulations among tumor infiltrating lymphocytes were analyzed by immunofluorescence, while the gene expression of MAGE-A1 and MAGE-A2 tumor-associated antigens was studied by RT-PCR. The results show that both the T cell infiltrate and the frequency of MAGE-A1/A2 gene expression were comparable in tumors and in autologous free-of-tumor tissues in bladder cancer, while the autologous free-of-tumor renal tissues showed reduced T cell infiltrate and frequency of MAGE gene expression as compared to the autologous tumors. Importantly, the intra-tumor T effector/Treg cell ratio was consistently <1 in bladder cancer patients (n. 7) who relapsed within two years, while it was always >1 in patients (n. 6) without recurrence (regardless of tumor stage) (P = 0.0006, Odds ratio = 195). These unprecedented findings clarify the pathogenic mechanism of bladder cancer recurrence and suggest that microscopically undetectable micro-foci of tumor may predispose to recurrence when associated with an inverted intratumoral T effector/Treg cell ratio. [less ▲]Detailed reference viewed: 94 (1 ULg) Hyaluronic acid and tendon lesionsKaux, Jean-François ; SAMSON, Antoine; Crielaard, Jean-Michel in Muscles, Ligaments and Tendons Journal (2016), 5(4 (eCollection 2015 Oct-Dec)), 264-269Introduction: Recently, the viscoelastic properties of hyaluronic acid on liquid connective tissue have been proposed for the treatment of tendinopathies. Some fundamental studies show encouraging results ... [more ▼]Introduction: Recently, the viscoelastic properties of hyaluronic acid on liquid connective tissue have been proposed for the treatment of tendinopathies. Some fundamental studies show encouraging results on hyaluronic acid’s ability to promote tendon gliding and reduce adhesion as well as to improve tendon architectural organisation. Some observations also support its use in a clinical setting to improve pain and function. This literature review analyses studies relating to the use of hyaluronic acid in the treatment of tendinopathies. Methods: This review was constructed using the Medline database via Pubmed, Scopus and Google Scholar. The keywords hyaluronic acid, tendon and tendinopathy were used for the research. Results: In total, 27 articles (in English and French) on the application of hyaluronic acid to tendons were selected for their relevance and scientific quality, including eight for the 'in vitro' part, three for the 'in vivo' animal part and six for the human section. Conclusions: Preclinical studies demonstrate encouraging results: HA permits tendon gliding, reduces adhesions, creates better tendon architectural organisation and limits inflammation. These laboratory observations appear to be supported by limited but encouraging short-term clinical results on pain and function. However, controlled randomised studies are still needed. [less ▲]Detailed reference viewed: 47 (8 ULg) Mapping of riparian invasive species with supervised classification of Unmanned Aerial System (UAS) imageryMichez, Adrien ; Piégay, Hervé; Lisein, Jonathan et alin International Journal of Applied Earth Observation and Geoinformation (2016), 44Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation ... [more ▼]Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation has increased during the 20th century. Concomitant with (or as consequences of) these disturbances, the invasion of exotic species has increased throughout the world’s riparian zones. In our study, we propose a easily reproducible methodological framework to map three riparian invasive taxa using Unmanned Aerial Systems (UAS) imagery: Impatiens glandulifera Royle, Heracleum mantegazzianum Sommier and Levier, and Japanese knotweed (Fallopia sachalinensis (F. Schmidt Petrop.), Fallopia japonica (Houtt.) and hybrids). Based on visible and near-infrared UAS orthophoto, we derived simple spectral and texture image metrics computed at various scales of image segmentation (10,30, 45, 60 using eCognition software). Supervised classification based on the random forests algorithm was used to identify the most relevant variable (or combination of variables) derived from UAS imagery for mapping riparian invasive plant species. The models were built using 20% of the dataset, the rest of the dataset being used as a test set (80%). Except for H. mantegazzianum, the best results in terms of global accuracy were achieved with the finest scale of analysis (segmentation scale parameter = 10). The best values of overall accuracies reached 72%, 68%, and 97% for I. glandulifera, Japanese knotweed, and H. mantegazzianum respectively. In terms of selected metrics, simple spectral metrics (layer mean / camera brightness) were the most used. Our results also confirm the added value of texture metrics (GLCM derivatives) for mapping riparian invasive species. The results obtained for I. glandulifera and Japanese knotweed do not reach sufficient accuracies for operational applications. However, the results achieved for H. mantegazzianum are encouraging. The high accuracies values combined to relatively light model-inputs needed (delineation of a few umbels) make our approach a serious contender as a cost-effective tool to improve the field management of H. mantegazzianum. [less ▲]Detailed reference viewed: 108 (37 ULg) Employee Emotional Competence: Construct Conceptualization and Validation of a Customer-Based MeasureDelcourt, Cécile ; Gremler, Dwayne; van Riel, Allard et alin Journal of Service Research (2016), 19(1), 72-87Customers often experience intense emotions during service encounters. Their perceptions of how well contact employees demonstrate emotional competence in emotionally charged service encounters can affect ... [more ▼]Customers often experience intense emotions during service encounters. Their perceptions of how well contact employees demonstrate emotional competence in emotionally charged service encounters can affect their service evaluations and loyalty intentions. Previous studies examining employees’ potential to behave in emotionally competent ways (i.e., employee emotional intelligence [EEI]) have used self- or supervisor-reported scales to predict customer outcomes, presenting EEI as stable and independent of the context. However, service firms should be more concerned with the actual display of emotionally competent behaviors by employees (employee emotional competence [EEC]), because employee behaviors vary across encounters. Moreover, a customer perspective of EEC is useful as customer perceptions of employee performance are crucial predictors of satisfaction and loyalty. Therefore, this study proposes a conceptualization and operationalization of EEC in a service encounter context. On the basis of a comprehensive literature review and in-depth interviews, the authors develop a scale to capture customer-perceived EEC, defined as an employee’s competence in perceiving, understanding, and regulating customer emotions during a discrete service encounter. The scale achieves good reliability and validity. Researchers can use it to explore the role of EEC in service contexts; managers can employ the scale to diagnose EEC and improve customers’ service encounter experiences. [less ▲]Detailed reference viewed: 125 (12 ULg) L'arrêt de mort des (trop) petites circonscriptions électorales wallonnesBouhon, Frédéric in Journal des Tribunaux (2016), 6634Cet article propose un commentaire de l'arrêt n° 169/2015 de la Cour constitutionnelle belge, par lequel elle a considéré que les règles législatives qui instaurent les plus petites circonscriptions ... [more ▼]Cet article propose un commentaire de l'arrêt n° 169/2015 de la Cour constitutionnelle belge, par lequel elle a considéré que les règles législatives qui instaurent les plus petites circonscriptions utilisées pour les élections du Parlement wallon sont inconstitutionnelles. L'article revient sur les enjeux du découpage du territoire en circonscriptions électorales, sur la jurisprudence antérieure en la matière et suggère un certain nombre d'adaptations que le législateur wallon pourrait adopter pour réagir à l'arrêt. [less ▲]Detailed reference viewed: 64 (16 ULg) Gallium-68-labelled NOTA-oligonucleotides: An optimized method for their preparationGijs, Marlies; Dammicco, Sylvestre ; Warnier, Corentin et alin Journal of Labelled Compounds & Radiopharmaceuticals (2016)One of the most essential aspects to the success of radiopharmaceuticals is an easy and reliable radiolabelling protocol to obtain pure and stable products. In this study, we optimized the bioconjugation ... [more ▼]One of the most essential aspects to the success of radiopharmaceuticals is an easy and reliable radiolabelling protocol to obtain pure and stable products. In this study, we optimized the bioconjugation and gallium-68 ((68) Ga) radiolabelling conditions for a single-stranded 40-mer DNA oligonucleotide, in order to obtain highly pure and stable radiolabelled oligonucleotides. Quantitative bioconjugation was obtained for a disulfide-functionalized oligonucleotide conjugated to the macrocylic bifunctional chelator MMA-NOTA (maleimido-mono-amide (1,4,7-triazanonane-1,4,7-triyl)triacetic acid). Next, this NOTA-oligonucleotide bioconjugate was radiolabelled at room temperature with purified and pre-concentrated (68) Ga with quantitative levels of radioactive incorporation and high radiochemical and chemical purity. In addition, high chelate stability was observed in physiological-like conditions (37 °C, PBS and serum), in the presence of a transchelator (EDTA) and transferrin. A specific activity of 51.1 MBq/nmol was reached using a 1470-fold molar excess bioconjugate over (68) Ga. This study presents a fast, straightforward and reliable protocol for the preparation of (68) Ga-radiolabelled DNA oligonucleotides under mild reaction conditions and without the use of organic solvents. The methodology herein developed will be applied to the preparation of oligonucleotidic sequences (aptamers) targeting the human epidermal growth factor receptor 2 (HER2) for cancer imaging. [less ▲]Detailed reference viewed: 20 (5 ULg) New perspectives for the design of sustainable bioprocesses for phosphorus recovery from wasteTarayre, Cédric ; De Clercq, Lies; Charlier, Raphaëlle et alin Bioresource Technology (2016), 206Phosphate rock has long been used for the production of phosphorus based chemicals. However, considering the depletion of the reservoirs and the decrease of the quality of phosphate rocks, a potential ... [more ▼]Phosphate rock has long been used for the production of phosphorus based chemicals. However, considering the depletion of the reservoirs and the decrease of the quality of phosphate rocks, a potential market is now emerging for the recovery of phosphate from waste and its reuse for different applications. Notably, phosphate recovery from wastewater could be included in a circular economy approach. This review focuses on the use of microbial systems for phosphorus accumulation and recovery, by considering the actual range of analytical techniques available for the monitoring of phosphorus accumulating organisms, as well as the actual biochemical and metabolic engineering toolbox available for the optimization of bioprocesses. In this context, knowledge gathered from process, system and synthetic biology could potentially lead to innovative process design. [less ▲]Detailed reference viewed: 32 (2 ULg) Numerical modeling of the long term behavior of Municipal Solid Waste in a bioreactor landfillHubert, Julien ; Xianfeng, Liu; Collin, Frédéric in Computers and Geotechnics (2016), 72This paper presents a thermo-hydro–biochemo-mechanical model for simulating the long term behavior of Municipal Solid Waste (MSW) in a bioreactor landfill, in which the multi-physics coupling mechanism ... [more ▼]This paper presents a thermo-hydro–biochemo-mechanical model for simulating the long term behavior of Municipal Solid Waste (MSW) in a bioreactor landfill, in which the multi-physics coupling mechanism plays a dominant role. In the model, a two-stage anaerobic biochemical model based on McDougall’s formulation is incorporated into a fully coupled thermo-hydro-mechanical models originally developed for unsaturated porous medium. The mechanical model is a modified Camclay model allowing for biochemical hardening/softening, while the thermal model is described by a classical energy balance equation with a source term accounting for the heat generation from the biodegradation of organic matter. The hydraulic model is an unsaturated flow model using Richard’s equation. The derived coupled model is implemented into an in-house built multi-physics finite element code. Finally, numerical simulations were performed to illustrate the capability of the proposed model for estimating long-term settlement of a bioreactor landfill and its aptitude as a landfill management tool for optimizing the landfill operation [less ▲]Detailed reference viewed: 51 (9 ULg) Quelques considérations pour adapter nos forêts aux changements climatiquesClaessens, Hugues in Silva Belgica (2016)Au cœur d’une grande forêt naturelle comme celle d’Anlier, de Saint-Hubert ou de Daverdisse, le promeneur ressent souvent une impression de calme et de stabilité. Cela pourrait faire penser que la forêt ... [more ▼]Au cœur d’une grande forêt naturelle comme celle d’Anlier, de Saint-Hubert ou de Daverdisse, le promeneur ressent souvent une impression de calme et de stabilité. Cela pourrait faire penser que la forêt est éternelle et sa forme immuable. Il n’en est rien, ce n’est qu’une question d’échelle temporelle, car depuis toujours, la forêt n’est que changement, dans sa surface, sa structure et sa composition, disparaissant parfois totalement pour recoloniser ensuite l’espace avec d’autres essences. [less ▲]Detailed reference viewed: 31 (6 ULg) Simultaneous production of acetic and gluconic acids by a thermotolerant Acetobacter strain during acetous fermentation in a bioreactorMounir, Majid ; shafiei, rasoul; Zarmehrkhorshid, Raziyeh et alin Journal of Bioscience & Bioengineering (2016), 121(2), 166-171The activity of bacterial strains significantly influences the quality and the taste of vinegar. Previous studies of acetic acid bacteria have primarily focused on the ability of bacterial strains to ... [more ▼]The activity of bacterial strains significantly influences the quality and the taste of vinegar. Previous studies of acetic acid bacteria have primarily focused on the ability of bacterial strains to produce high amounts of acetic acid. However, few studies have examined the production of gluconic acid during acetous fermentation at high temperatures. The production of vinegar at high temperatures by two strains of acetic acid bacteria isolated from apple and cactus fruits, namely AF01 and CV01, respectively, was evaluated in this study. The simultaneous production of gluconic and acetic acids was also examined in this study. Biochemical and molecular identification based on a 16s rDNA sequence analysis confirmed that these strains can be classified as Acetobacter pasteurianus. To assess the ability of the isolated strains to grow and produce acetic acid and gluconic acid at high temperatures, a semi-continuous fermentation was performed in a 20-L bioreactor. The two strains abundantly grew at a high temperature (41°C). At the end of the fermentation, the AF01 and CV01 strains yielded acetic acid concentrations of 7.64% (w/v) and 10.08% (w/v), respectively. Interestingly, CV01 was able to simultaneously produce acetic and gluconic acids during acetic fermentation, whereas AF01 mainly produced acetic acid. In addition, CV01 was less sensitive to ethanol depletion during semi-continuous fermentation. Finally, the enzymatic study showed that the two strains exhibited high ADH and ALDH enzyme activity at 38°C compared with the mesophilic reference strain LMG 1632, which was significantly susceptible to thermal inactivation. [less ▲]Detailed reference viewed: 46 (8 ULg) COMMENT J'EXPLORE... LA BIPOLARITE EN PEDOPSYCHIATRIE : UNE SEMIOLOGIE DIMENSIONNELLESCHOLL, Jean-Marc in Revue Médicale de Liège (2016), 71(2), 94-100Despite its high frequency, bipolarity in childhood is little understood and is often diagnosed only after several years of development, and this during a time when the child’s psychosocial future is at ... [more ▼]Despite its high frequency, bipolarity in childhood is little understood and is often diagnosed only after several years of development, and this during a time when the child’s psychosocial future is at stake. A proper diagnosis requires recognition of accurate clinical signs. It is therefore essential to furnish clinicians with precise semiological markers. This paper presents a dimensional semiology for use in anamnesis and in clinical observation of the child. These clinical signs enable the identification of a bipolar manic temperament in the child and/or the identification of various different forms of childhood bipolar and depressive disorder. The relevant differential diagnoses and comorbidities are also presented. [less ▲]Detailed reference viewed: 97 (20 ULg) Dynamics of Internalization and Recycling of the Pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer CellsTruong, Alice ; Yip, Cassandre ; PAYE, Alexandra et alin FEBS Journal (2016), 283(4), 704-22MT4-MMP (MMP17) is a glycosylphosphatidyl inositol (GPI)-anchored membrane-type MMP expressed on the cell surface of human breast cancer cells. In triple negative breast cancer cells, MT4-MMP promotes ... [more ▼]MT4-MMP (MMP17) is a glycosylphosphatidyl inositol (GPI)-anchored membrane-type MMP expressed on the cell surface of human breast cancer cells. In triple negative breast cancer cells, MT4-MMP promotes primary tumor growth and lung metastases. Although trafficking and internalization of the transmembrane MT1-MMP have been extensively investigated, little is known about the regulatory mechanisms of the GPI-anchored MT4-MMP. Here, we investigated the fate and cellular trafficking of MT4-MMP by analyzing its homophilic complex interactions, internalization and recycling dynamics compared to an inert form, MT4-MMP-E249A. Oligomeric and dimeric complexes were analyzed by co-transfection of cells with FLAG- or Myc-tagged MT4-MMP by reducing and non-reducing immunoblots and co-immunoprecipitation experiments. The trafficking of MT4-MMP was studied using an antibody feeding assay and confocal microscopy analysis or cell surface protein biotinylation and Western blot analysis. We demonstrate that MT4-MMP forms homophilic complexes at the cell surface, internalizes in early endosomes, and some of the enzyme is either auto-degraded or recycled to the cell surface. Our data indicate that MT4-MMP is internalized by the CLIC/GEEC pathway, a mechanism that differs from other MT-MMP members. Although MT4-MMP localizes with caveolin-1, MT4-MMP internalization was not affected by inhibitors of caveolin-1 or clathrin endocytosis pathways but was reduced by cdc42 or RhoA silencing with siRNA. We provide a new mechanistic insight into the regulatory mechanisms of MT4-MMP, which may have implications in the design of novel therapeutic strategies for metastatic breast cancer. This article is protected by copyright. All rights reserved. [less ▲]Detailed reference viewed: 139 (19 ULg) Vers un modèle d’apprentissage réflexif. Recueil de traces d’apprentissage formulées dans les log books des stagiaires en médecineVierset, Viviane in Approches Inductives (2016)Detailed reference viewed: 26 (5 ULg) Dynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing FactorsStankovic, Nancy ; Schloesser, Marie ; Joris, Marine et alin Plant Physiology (2016), 170Serine/Arginine-rich (SR) proteins are essential nucleus-localized splicing factors. Our prior studies showed that Arabidopsis RSZ22, a homolog of the human SRSF7 SR factor, exits the nucleus through two ... [more ▼]Serine/Arginine-rich (SR) proteins are essential nucleus-localized splicing factors. Our prior studies showed that Arabidopsis RSZ22, a homolog of the human SRSF7 SR factor, exits the nucleus through two pathways, either dependent or independent on the XPO1 receptor. Here, we examined the expression profiles and shuttling dynamics of the Arabidopsis SRSF1 subfamily (SR30, SR34, SR34a and SR34b) under control of their endogenous promoter in Arabidopsis and in transient expression assay. Due to its rapid nucleocytoplasmic shuttling and high expression level in transient assay, we analysed the multiple determinants that regulate the localisation and shuttling dynamics of SR34. By site-directed mutagenesis of SR34 RNA-binding sequences and RS domain, we further show that functional RRM1 or RRM2 are dispensable for the exclusive protein nuclear localization and speckle-like distribution. However, mutations of both RRMs induced aggregation of the protein whereas mutation in the RS domain decreased the stability of the protein and suppressed its nuclear accumulation. Furthermore, the RNA-binding motif mutants are defective for their export through the XPO1 (CRM1/Exportin-1) receptor pathway, but retain nucleocytoplasmic mobility. We performed a yeast two hybrid screen with SR34 as bait and discovered SR45 as a new interactor. SR45 is an unusual SR splicing factor bearing two RS domains. These interactions were confirmed in planta by FLIM-FRET and BiFC and the roles of SR34 domains in protein-protein interactions were further studied. Altogether, our report extends our understanding of shuttling dynamics of Arabidopsis SR splicing factors [less ▲]Detailed reference viewed: 67 (28 ULg) Prospects of a new dynamic simulation software for real-time applications on the Hydro-Québec systemAristidou, Petros; Lebeau, Simon; Loud, Lester et alin CIGRE Science and Engineering (2016), 4Hydro-Québec has a long interest in on-line Dynamic Security Assessment (DSA) driven by its challenging system dynamics. Presently, off-line calculated security limits are combined with an on-line ... [more ▼]Hydro-Québec has a long interest in on-line Dynamic Security Assessment (DSA) driven by its challenging system dynamics. Presently, off-line calculated security limits are combined with an on-line monitoring system. However, new developments in dynamic simulation enable real-time or near-real-time DSA calculations and transfer limits determination. In this paper, the domain-decomposition-based algorithm implemented in the simulator RAMSES is presented, along with techniques to accelerate its sequential and parallel executions. RAMSES exploits the localized response to disturbances and the timescale decomposition of dynamic phenomena to provide sequential acceleration when the simulation is performed on a single processing unit. Additionally, when more units are available, the parallelization potential of domain-decomposition methods is exploited for further acceleration. The algorithm and techniques have been tested on a realistic model of the Hydro-Québec system to evaluate the accuracy of dynamic responses and the sequential and parallel performances. Finally, the real-time capabilities have been assessed using a shared-memory parallel processing platform. [less ▲]Detailed reference viewed: 45 (3 ULg) Traumatologie du rugby à VIIKAUX, Jean-François ; Julia, Marc; Delvaux, François et alin Science & Sports (2016), 31(1), 1-5Aims. — To estimate the risk of injury in rugby sevens.News. — The rugby sevens is an increasingly popular sport since the creation of the IRB SevensWorld Series in 2000 and its introduction as an Olympic ... [more ▼]Aims. — To estimate the risk of injury in rugby sevens.News. — The rugby sevens is an increasingly popular sport since the creation of the IRB SevensWorld Series in 2000 and its introduction as an Olympic sport in 2016. Despite its strong simi-larities to rugby union, it remains a different sport with higher game intensity, causing a moresignificant number of injuries. The average incidence of injury in rugby sevens is 249.27 for1000 hours of play against 102.25 for 1000 hours of rugby union matches.Conclusion. — This epidemiological review of injuries among the rugby sevens refers to theirlocation and their nature, the causes, the position of players, the type of field, as well as thedowntime of practice following trauma. [less ▲]Detailed reference viewed: 89 (32 ULg) Does biobased polymer achieve better environmental impacts than fossil polymer? Comparison of fossil HDPE and biobased HDPE produced from sugar beet and wheatBelboom, Sandra ; Léonard, Angélique in Biomass & Bioenergy (2016), 85Polymers are one of the most used materials and the majority of their production is based on fossil fuels. Due to the decrease of oil resources and concerns about climate change, alternatives are needed ... [more ▼]Polymers are one of the most used materials and the majority of their production is based on fossil fuels. Due to the decrease of oil resources and concerns about climate change, alternatives are needed, the transformation of biobased ethanol into biobased polymer being one of them. This paper undertakes an environmental evaluation of the production of biobased polymer produced from two different feedstock cultivated in Belgium: sugar beet and wheat. Both crops cultivation are studied as well as their transformation into biobased ethanol, first, and then to biobased ethylene, focusing on high-density polyethylene (HDPE) as final product. These scenarios are analyzed and compared with the production of conventional polymer using the life-cycle assessment (LCA) methodology with reference to relevant environmental impact categories. This study shows a reduction of impact of around 60% for both climate change and fossil fuel depletion categories when using biobased HDPE instead of its fossil counterpart. For all other impact categories, fossil HDPE achieves better results than the biobased product. [less ▲]Detailed reference viewed: 69 (8 ULg) No favorable effect of reduced tillage on microbial community diversity in a silty loam soil (Belgium)Degrune, Florine ; Theodorakopoulos, Nicolas ; Dufrêne, Marc et alin Agriculture, Ecosystems & Environment (2016), 224Among the soil management practices used to promote sustainable agriculture, reduced tillage and retention of residues from the previous crop are reported to enhance significantly both soil fertility and ... [more ▼]Among the soil management practices used to promote sustainable agriculture, reduced tillage and retention of residues from the previous crop are reported to enhance significantly both soil fertility and crop productivity. Here, high-throughput sequencing (454 technology) was used to see how the tillage regime (conventional vs. reduced tillage) and the fate of crop residues (retention or removal) affect microbial communities at two sampling depths (top soil: 0–5 cm and deeper soil: 15–20 cm) in a fertile silty loam soil in Belgium. All combinations of these three factors were studied. After 6 years of conversion from conventional to reduced tillage, depth emerged as the main factor responsible for variation in microbial diversity, tillage regime ranked second, and finally, crop residue fate had no influence on microbial diversity. For both bacteria and fungi, the diversity appeared higher in the top soil than in the deeper soil, and surprisingly, higher under conventional than under reduced tillage. These differences are explained by changes in community composition due to taxon loss rather than taxon replacement. The specific local set of environmental conditions (a loess-derived soil and an oceanic temperate climate) may explain these results. These observations raise the question: does impoverishment in indicator taxa influence soil processes, and thus crop production? To answer this question, we discuss how the presence of certain indicator taxa liable to play an ecological role might relate to crop productivity. [less ▲]Detailed reference viewed: 68 (39 ULg) The impact of dissolved organic carbon and bacterial respiration on pCO2 in experimental sea iceZhou, Jiayun; Kotovitch, Marie ; Kaartokallio, H. et alin Progress in Oceanography (2016), 141Previous observations have shown that the partial pressure of carbon dioxide (pCO2) in sea ice brines is generally higher in Arctic sea ice compared to those from the Antarctic sea ice, especially in ... [more ▼]Previous observations have shown that the partial pressure of carbon dioxide (pCO2) in sea ice brines is generally higher in Arctic sea ice compared to those from the Antarctic sea ice, especially in winter and early spring. We hypothesized that these differences result from the higher dissolved organic carbon (DOC) content in Arctic seawater: Higher concentrations of DOC in seawater would be reflected in a greater DOC incorporation into sea ice, enhancing bacterial respiration, which in turn would increase the pCO2 in the ice. To verify this hypothesis, we performed an experiment using two series of mesocosms: one was filled with seawater (SW) and the other one with seawater with an addition of filtered humic-rich river water (SWR). The addition of river water increased the DOC concentration of the water from a median of 142 µmol L-1 in SW to 249 µmol L-1 in SWR. Sea ice was grown in these mesocosms under the same physical conditions over 19 days. Microalgae and protists were absent, and only bacterial activity has been detected. We measured the DOC concentration, bacterial respiration, total alkalinity and pCO2 in sea ice and the underlying seawater, and we calculated the changes in dissolved inorganic carbon (DIC) in both media. We found that bacterial respiration in ice was higher in SWR: median bacterial respiration was 25 nmol C L-1 h-1 compared to 10 nmol C L-1 h-1 in SW. pCO2 in ice was also higher in SWR with a median of 430 ppm compared to 356 ppm in SW. However, the differences in pCO2 were larger within the ice interiors than at the surfaces or the bottom layers of the ice, where exchanges at the air-ice and ice-water interfaces might have reduced the differences. In addition, we used a model to simulate the differences of pCO2 and DIC based on bacterial respiration. The model simulations support the experimental findings and further suggest that bacterial growth efficiency in the ice might be 0.15-0.2. It is thus credible that the higher pCO2 in Arctic sea ice brines compared with those from the Antarctic sea ice were due to an elevated bacterial respiration, sustained by higher riverine DOC loads. These conclusions should hold for locations and time frames when bacterial activity is relatively dominant compared to algal activity, considering our experimental conditions. [less ▲]Detailed reference viewed: 57 (6 ULg) On the equivalent static load method for flexible multibody systems described with a nonlinear finite element formalismTromme, Emmanuel ; Sonneville, Valentin ; Bruls, Olivier et alin International Journal for Numerical Methods in Engineering (2016)The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response ... [more ▼]The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response optimization under multiple load cases. The ESL cases are defined based on the transient analysis response whereupon all the standard techniques of static response optimization can be used. In the last decade, the ESL method has been applied to perform the structural optimization of flexible components of mechanical systems modeled as multibody systems (MBS). The ESL evaluation strongly depends on the adopted formulation to describe the MBS and has been initially derived based on a floating frame of reference formulation. In this paper, we propose a method to derive the ESL adapted to a nonlinear finite element approach based on a Lie group formalism for two main reasons. Firstly, the finite element approach is completely general to analyze complex MBS and is suitable to perform more advanced optimization problems like topology optimization. Secondly, the selected Lie group formalism leads to a formulation of the equations of motion in the local frame, that turns out to be a strong practical advantage for the ESL evaluation. Examples are provided to validate the proposed method. [less ▲]Detailed reference viewed: 41 (4 ULg)