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See detailLe gingembre, antiémétique de premier choix dans la pratique officinale
Angenot, Luc ULg

in Pharma-Sphère (2014), 18(195), 30-31

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See detailTriple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes
Chiavarina, Barbara ULg; Nokin, Marie-Julie; Durieux, Florence ULg et al

in Oncotarget (2014)

Metabolic syndrome and type 2 diabetes are associated with increased risk of breast cancer development and progression. Methylglyoxal (MG), a glycolysis by- product, is generated through a non-enzymatic ... [more ▼]

Metabolic syndrome and type 2 diabetes are associated with increased risk of breast cancer development and progression. Methylglyoxal (MG), a glycolysis by- product, is generated through a non-enzymatic reaction from triose-phosphate intermediates. This dicarbonyl compound is highly reactive and contributes to the accumulation of advanced glycation end products. In this study, we analyzed the accumulation of Arg-pyrimidine, a MG-arginine adduct, in human breast adenocarcinoma and we observed a consistent increase of Arg-pyrimidine in cancer cells when compared with the non-tumoral counterpart. Further immunohistochemical comparative analysis of breast cancer subtypes revealed that triple negative lesions exhibited low accumulation of Arg-pyrimidine compared with other subtypes. Interestingly, the activity of glyoxalase 1 (Glo-1), an enzyme that detoxifies MG, was significantly higher in triple negative than in other subtype lesions, suggesting that these aggressive tumors are able to develop an efficient response against dicarbonyl stress. Using breast cancer cell lines, we substantiated these clinical observations by showing that, in contrast to triple positive, triple negative cells induced Glo-1 expression and activity in response to MG treatment. This is the first report that Arg- pyrimidine adduct accumulation is a consistent event in human breast cancer with a differential detection between triple negative and other breast cancer subtypes. [less ▲]

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See detailModélisation de la canopée forestière par photogrammétrie depuis des images acquises par drone
Lisein, Jonathan ULg; Bonnet, Stéphanie ULg; Lejeune, Philippe ULg et al

in Revue Française de Photogrammétrie et de Télédétection (2014), 206

Les petits drones civils développés à des fins de cartographie rapide offrent, à une échelle locale, de nombreuses opportunités pour le suivi d’écosystèmes forestiers. Nous utilisons dans cette recherche ... [more ▼]

Les petits drones civils développés à des fins de cartographie rapide offrent, à une échelle locale, de nombreuses opportunités pour le suivi d’écosystèmes forestiers. Nous utilisons dans cette recherche des images acquises avec un avion sans pilote à voilure fixe afin de modéliser la surface de la canopée de peuplements feuillus. Une chaine de traitements photogrammétriques est mise en place au moyen des outils de la suite open source MICMAC. Nous comparons différentes stratégies de corrélation automatique d’images afin de déterminer le paramétrage qui permet au mieux de reconstruire les détails de la canopée. Bien que le modèle de surface photogrammétrique ne permette pas d’appréhender les petites dépressions et élévations des houppiers, nos résultats montrent que l’utilisation conjointe d’images drone et d’un modèle numérique de terrain LiDAR permet d’estimer la hauteur dominante des peuplements feuillus. Ces résultats confirment la faisabilité de modéliser l’évolution de la hauteurs des peuplements forestiers depuis une série temporelle d’images drone. [less ▲]

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See detailComment gérer la nutrition artificielle chez un patient diabétique ?
PAQUOT, Nicolas ULg; DE FLINES, Jenny ULg; PREISER, Jean-Charles ULg

in Nutrition Clinique et Metabolisme (2014)

Hyperglycaemia in patients receiving enteral or parenteral nutrition is a major problem due to its high prevalence and possible consequences interms of morbidity and mortality. However, the management of ... [more ▼]

Hyperglycaemia in patients receiving enteral or parenteral nutrition is a major problem due to its high prevalence and possible consequences interms of morbidity and mortality. However, the management of diabetes/stress hyperglycaemia during artificial nutrition remains largely unknown,especially in non-critically ill patients. The indications and access routes for artificial nutrition are not different in patients with diabetes/stressdiabetes than in non-diabetics. We do not recommend using enteral formulas designed for patients with diabetes. The glycaemic objective mustbe individualized. We recommend a preprandial blood glucose levels between 100 and 140 mg/dL (5.5 and 7.8 mmol/L) and postprandial levelsbetween 140 and 180 mg/dL (7.8 and 10 mmol/L). A frequent monitoring of capillary glycaemias is mandatory. The best drug treatment for treatinghyperglycaemia/diabetes is insulin and we recommend to adapt the theoretical insulin action to the nutrition infusion regimen. The managementof these patients needs the help of a multidisciplinary experimented staff. [less ▲]

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See detailInfusion of clinical-grade enriched regulatory T cells delays experimental xenogeneic graft-versus-host disease
Hannon, Muriel ULg; LECHANTEUR, Chantal ULg; Lucas, Sophie et al

in Transfusion (2014), 54(February), 353-363

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See detailAssessment of water quality effects on flotation of copper-cobalt oxide ore
Shengo, Michel; Gaydardzhiev, Stoyan ULg; Kalenga, Pierre

in Minerals Engineering (2014), 65

Results from lab scale flotation show that when process water was re-used copper and cobalt recovery from an oxidized ore decreased respectively with 25 and 30 percent at the rougher stage bringing lower ... [more ▼]

Results from lab scale flotation show that when process water was re-used copper and cobalt recovery from an oxidized ore decreased respectively with 25 and 30 percent at the rougher stage bringing lower grade concentrate as well. The presence of thiosulphate ions contributed to slow down of NaHS consumption during sulphidization of pure malachite and hindered collector adsorption. Elevated concentration of thiosulphate ions affected malachite surface properties and induced dissolution effects. DRIFT spectroscopy on activated malachite enabled to reveal the effects of thiosulphate ions presence with hydrophilic species being identified. [less ▲]

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See detailDesign and fabrication of an electrode array sensor for probing the electric potential distribution at the mesoscopic scale in antistatic felts
Boutaayamou, Mohamed ULg; Lemaire, Philippe; Vanderheyden, Benoît ULg et al

in Measurement Science and Technology (2014), 25

We present an original voltage probe design for measuring the electric potential distribution at the mesoscopic scale (i.e., 1 mm–1 cm) in antistatic felts. The felts are composed of a mixture of non ... [more ▼]

We present an original voltage probe design for measuring the electric potential distribution at the mesoscopic scale (i.e., 1 mm–1 cm) in antistatic felts. The felts are composed of a mixture of non-conductive and metallic fibers and exhibit complex nonlinear electric behavior—including possibly nonlinearity and hysteresis effects—which may be due to localized electrical or electromechanical phenomena. The sensor consists of an array of 8 × 9 needle electrodes (phgr 160 µm at the shaft and less than phgr 50 µm toward the apex), which are mechanically maintained at fixed relative positions while their tips are inserted inside the fabric of the sample. The interelectrode distance is 1.5 mm and the overall active area is 12 × 12 mm². The electrical insulation resistance for nearest neighbor pairs of electrodes was found to be larger than 860 GΩ, thus making the sensor suitable for measuring antistatic felts with an electric resistance that typically does not exceed a few GΩ. The sensor was successfully used for measuring the distribution of the electric potential in a polyester fabric subjected to voltages of up to 6.2 kV, and in a sample containing 2% in weight of metallic fibers, demonstrating the presence of irreversible changes in that felt sample (i.e., with conductive fibers) at high voltages. It is concluded that the developed probe voltage is a promising technique that could be used for the assessment of the conduction mechanisms in the antistatic materials at the mesoscopic scale. [less ▲]

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See detailEffect of entomopathogenic Aspergillus strains against the pea aphid, Acyrthosiphon pisum (Hemiptera: Aphididae)
Seye, Fawrou; Bawin, Thomas ULg; Boukraa, Slimane ULg et al

in Applied Entomology and Zoology (2014)

Aphids (Homoptera: Aphididae) are sap-sucking insect pests that feed on several plants of agronomical importance. Entomopathogenic fungi are valuable tools for potential aphid control. As part of a ... [more ▼]

Aphids (Homoptera: Aphididae) are sap-sucking insect pests that feed on several plants of agronomical importance. Entomopathogenic fungi are valuable tools for potential aphid control. As part of a selection process, laboratory bioassays were carried with five different concentrations of Aspergillus clavatus (Desmazières), Aspergillus flavus (Link) and Metarhizium anisopliae ((Metschnikoff) Sorokin) spores against the pea aphid, Acyrthosiphon pisum (Harris). Aspergillus isolates induced higher mortalities than M. anisopliae which is a well-known entomopathogen in the literature. Lethal concentrations (LC50 and LC90) were 1.23 x 10^3 and 1.34 x 10^7 spores/ml for A. flavus, 4.95 x 10^2 and 5.65 x 10^7 spores/ml for A. clavatus, and 3.67 x 10^3 and 9.71 x 10^7 spores/ml for M. anisopliae five days after treatment. Mycelia development and sporulation on adult cadavers was observed 48 hours after incubation. The intrinsic growth rate of A. pisum decreased with increased spore concentration for all fungal strains suggesting an increase in pathogen fitness related to a consumption of host resources. In conclusion, Aspergillus species could be useful in aphid control as pest control agents despite their saprophytic lifestyle. This is also in our knowledge the first report of A. clavatus and A. flavus strains pathogenic to aphids. [less ▲]

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See detailVery deep images of the innermost regions of the beta Pictoris debris disc at L'
Milli, J.; Lagrange, A.-M.; Mawet, D. et al

in Astronomy and Astrophysics (2014), 566

Context. Very few debris discs have been imaged in scattered light at wavelengths beyond 3 mum because the thermal emission from both the sky and the telescope is generally too strong with respect to the ... [more ▼]

Context. Very few debris discs have been imaged in scattered light at wavelengths beyond 3 mum because the thermal emission from both the sky and the telescope is generally too strong with respect to the faint emission of a debris disc. We present here the first analysis of a high angular resolution image of the disc of beta Pictoris at 3.8 mum. <BR /> Aims: Our primary objective is to probe the innermost parts of the beta Pictoris debris disc and describe its morphology. We performed extensive forward modelling to correct for the biases induced by angular differential imaging on extended objects and derive the physical parameters of the disc. <BR /> Methods: This work relies on a new analysis of seven archival data sets of beta Pictoris observed with the NaCo instrument at the Very Large Telescope in the L' band, including observations made with the Annular Groove Phase Mask vortex coronagraph in 2013. The data analysis consists of angular differential imaging associated with disc forward modelling to correct for the biases induced by that technique. The disc model is subtracted from the data and the reduction performed again in order to minimize the residuals in the final image. <BR /> Results: The disc is detected above a 5sigma level between 0.4'' and 3.8''. The two extensions have a similar brightness within error bars. We confirm an asymmetry previously observed at larger distances from the star and at shorter wavelengths: the isophotes are more widely spaced [less ▲]

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See detailDiscovery of X-ray pulsations from a massive star
Oskinova, Lidia M.; Nazé, Yaël ULg; Todt, Helge et al

in Nature Communications (2014), 5

X-ray emission from stars much more massive than the Sun was discovered only 35 years ago. Such stars drive fast stellar winds where shocks can develop, and it is commonly assumed that the X-rays emerge ... [more ▼]

X-ray emission from stars much more massive than the Sun was discovered only 35 years ago. Such stars drive fast stellar winds where shocks can develop, and it is commonly assumed that the X-rays emerge from the shock-heated plasma. Many massive stars additionally pulsate. However, hitherto it was neither theoretically predicted nor observed that these pulsations would affect their X-ray emission. All X-ray pulsars known so far are associated with degenerate objects, either neutron stars or white dwarfs. Here we report the discovery of pulsating X-rays from a non-degenerate object, the massive B-type star ξ[SUP]1[/SUP] CMa. This star is a variable of β Cep-type and has a strong magnetic field. Our observations with the X-ray Multi-Mirror (XMM-Newton) telescope reveal X-ray pulsations with the same period as the fundamental stellar oscillations. This discovery challenges our understanding of stellar winds from massive stars, their X-ray emission and their magnetism. [less ▲]

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See detailPhase resolved X-ray spectroscopy of HDE 228766: Probing the wind of an extreme Of+/WNLha star
Rauw, Grégor ULg; Mahy, Laurent; Nazé, Yaël ULg et al

in Astronomy and Astrophysics (2014), 566

Context. HDE 228766 is a very massive binary system hosting a secondary component, which is probably in an intermediate evolutionary stage between an Of supergiant and an WN star. The wind of this star ... [more ▼]

Context. HDE 228766 is a very massive binary system hosting a secondary component, which is probably in an intermediate evolutionary stage between an Of supergiant and an WN star. The wind of this star collides with the wind of its O8 II companion, leading to relatively strong X-ray emission. <BR /> Aims: Measuring the orbital variations of the line-of-sight absorption toward the X-ray emission from the wind-wind interaction zone yields information on the wind densities of both stars. <BR /> Methods: X-ray spectra have been collected at three key orbital phases to probe the winds of both stars. Optical photometry has been gathered to set constraints on the orbital inclination of the system. <BR /> Results: The X-ray spectra reveal prominent variations of the intervening column density toward the X-ray emission zone, which are in line with the expectations for a wind-wind collision. We use a toy model to set constraints on the stellar wind parameters by attempting to reproduce the observed variations of the relative fluxes and wind optical depths at 1 keV. <BR /> Conclusions: The lack of strong optical eclipses sets an upper limit of ~ 68° on the orbital inclination. The analysis of the variations of the X-ray spectra suggests an inclination in the range 54-61° and indicates that the secondary wind momentum ratio exceeds that of the primary by at least a factor 5. Our models further suggest that the bulk of the X-ray emission arises from the innermost region of the wind interaction zone, which is from a region whose outer radius, as measured from the secondary star, lies between 0.5 and 1.5 times the orbital separation. Based on observations collected with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA member states and the USA (NASA), and on data collected at the San Pedro Mártir observatory (Mexico). [less ▲]

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See detailThe four duties of family doctors. Quaternary prevention: First, do no harm
Jamoulle, Marc ULg

in Hong Kong Practitioner (2014), 36

Cl inical prevent ion has been organised in a chronological manner since the middle of the 20th century. A paradigm shift from a chronological to a relationship-based preventive pattern of care offers new ... [more ▼]

Cl inical prevent ion has been organised in a chronological manner since the middle of the 20th century. A paradigm shift from a chronological to a relationship-based preventive pattern of care offers new insight into the practice of doctors, and brings to light the concept of quaternary prevention, a critical look at medical activities with an emphasis on the need not to harm. Quaternary prevention addresses the fundamental question of what constitutes too much or too little medicine. It is the fourth form of disease prevention, but also the fourth frame of action for family doctors. New definitions of prevention published in the Wonca Dictionary of Family Medicine offer a structured way to discuss the activities of family doctors, including ethical considerations on the patient-doctor encounter. 摘要 [less ▲]

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See detailA quest for meta-learning gains in a physics serious game
Verpoorten, Dominique ULg; Castaigne, J.-L.; Westera, W. et al

in Education & Information Technologies (2014), 19(2), 361-374

This paper describes how a short, repeated and structured opportunity to reflect was integrated in the storyline of a serious game in order to stimulate the development of a meta-cognitive skill: the ... [more ▼]

This paper describes how a short, repeated and structured opportunity to reflect was integrated in the storyline of a serious game in order to stimulate the development of a meta-cognitive skill: the ability to self-assess the degree of confidence in own answers. An empirical validation of the approach, conducted with 28 secondary school pupils, delivers an uncommon pattern: while the cognitive benefits-the acquisition of academic knowledge in optics-are negligible and mixed up, the meta-cognitive gains present a raising tendency. The experiment also demonstrates that reflection does not necessarily hamper the game flow, if certain conditions, discussed in the paper, are met. © 2012 Springer Science+Business Media New York. [less ▲]

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See detailExtremely Organic-rich Coma of Comet C/2010 G2 (Hill) during its Outburst in 2012
Kawakita, Hideyo; Dello Russo, Neil; Vervack, Ron et al

in Astrophysical Journal (2014), 788

We performed high-dispersion near-infrared spectroscopic observations of comet C/2010 G2 (Hill) at 2.5 AU from the Sun using NIRSPEC (R ≈ 25,000) at the Keck II Telescope on UT 2012 January 9 and 10 ... [more ▼]

We performed high-dispersion near-infrared spectroscopic observations of comet C/2010 G2 (Hill) at 2.5 AU from the Sun using NIRSPEC (R ≈ 25,000) at the Keck II Telescope on UT 2012 January 9 and 10, about a week after an outburst had occurred. Over the two nights of our observations, prominent emission lines of CH[SUB]4[/SUB] and C[SUB]2[/SUB]H[SUB]6[/SUB], along with weaker emission lines of H[SUB]2[/SUB]O, HCN, CH[SUB]3[/SUB]OH, and CO were detected. The gas production rate of CO was comparable to that of H[SUB]2[/SUB]O during the outburst. The mixing ratios of CO, HCN, CH[SUB]4[/SUB], C[SUB]2[/SUB]H[SUB]6[/SUB], and CH[SUB]3[/SUB]OH with respect to H[SUB]2[/SUB]O were higher than those for normal comets by a factor of five or more. The enrichment of CO and CH[SUB]4[/SUB] in comet Hill suggests that the sublimation of these hypervolatiles sustained the outburst of the comet. Some fraction of water in the inner coma might exist as icy grains that were likely ejected from nucleus by the sublimation of hypervolatiles. Mixing ratios of volatiles in comet Hill are indicative of the interstellar heritage without significant alteration in the solar nebula. [less ▲]

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See detailQuality assessment of marketed eggs in Eastern Algeria
Kara Ali, Monira; Ait Kaki, Asma ULg; Milet, Asma et al

in Nature & Technologie (2014), 11(2), 52-58

The objective of this study was to compare eggs quality between industrial and local chickens in four departments of Eastern Algeria (Bejaia, Jijel, Mila and Setif). A total of 4748 eggs were bought from ... [more ▼]

The objective of this study was to compare eggs quality between industrial and local chickens in four departments of Eastern Algeria (Bejaia, Jijel, Mila and Setif). A total of 4748 eggs were bought from three marketing channels as following: shops (1184), public markets (2757) and supermarkets (807). The percentage of stained eggs was significantly different (P<0.001) between industrial (15.25%) and local eggs (27.61%). A significant difference (P<0.05) was observed between industrial and local egg weight (61.01 vs 53.28g), egg shell weight (7.10 vs 6.30g), albumen weight (37.44 vs 29.69g), albumen percentage (61.34 vs 55.71%), shell thickness (0.381 vs 0.325mm). However, yolk weight (6.10 vs 6.30g), yolk percentage (27.06 vs 32.44%), shell percentage (11.60 vs 11.89%), yolk/albumen ratio (0.44 vs 0.58), albumen height (5.27 vs 5.93mm), Haugh unit (69.12 vs 77.80), yolk color (9.52 vs 10.94) and egg price (7.67 vs 12.84DA) of local chicken were significantly (P<0.01) higher than in the case of industrial hen. Marketing channels affected significantly (P<0.01) egg weight, yolk weight, albumen weight, albumen height and price of a total studied eggs. Egg weight (59.03g) and egg price (10.87DA) from supermarkets were the highest. Eggs of local hens presented according to the national preference, interesting quality criteria such as freshness, yolk/albumen ratio and yolk color. [less ▲]

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See detailBook Review : Marc Hersant, Le discours de vérité dans les mémoires du duc de Saint-Simon
Donneau, Olivier ULg

in French History (2014), 28(2), 287

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See detailPontormo dibujos, exposition par Mónica Fuentes Santos (Madrid, Fundación MAPFRE 12 février-11 mai)
Geremicca, Antonio ULg

in Archivo Espanol de Arte (2014), LXXXVII(346), 206-207

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See detailMicro-plasto-hydrodynamic lubrication: a fundamental mechanism in cold rolling
Laugier, Maxime; Boman, Romain ULg; Legrand, Nicolas et al

in Advanced Materials Research (2014), 966-967

Micro Plasto-Hydrodynamic (MPH) lubrication is a general mechanism in metal forming that consists in a re-lubrication of tool-piece solid contacts by an outflow of lubricant from pressurized “pockets” ... [more ▼]

Micro Plasto-Hydrodynamic (MPH) lubrication is a general mechanism in metal forming that consists in a re-lubrication of tool-piece solid contacts by an outflow of lubricant from pressurized “pockets” promoted by the plastic deformation. MPH lubrication is one of the main sources of friction variation (e.g. uncontrolled friction) in metal forming processes like strip drawing or cold rolling. This paper presents experimental results giving evidence of the MPH lubrication mechanism in cold rolling and a new lubrication model that predicts for strip drawing conditions MPH lubrication initiation and lubricant extension along the solid contacts initially in boundary condition. This MPH model could be implemented in a cold rolling model soon to help in high strength steels developments on cold rolling mills. [less ▲]

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See detailL'impact de la gestion de la mobilité par les entreprises wallonnes sur les déplacements domicile-travail
Halleux, Jean-Marie ULg; Vandermeer, Marie-Caroline ULg

in Recherche - Transports - Securité (2014), 2014(2-3), 83-100

Although mobility management by employers is an increasingly common practice, literature is scarce on the real impact of the applied measures. In this perspective, the objective of this paper is to assess ... [more ▼]

Although mobility management by employers is an increasingly common practice, literature is scarce on the real impact of the applied measures. In this perspective, the objective of this paper is to assess the impact on car use of the measures adopted by employers located in Wallonia. In order to achieve this objective, the article develops simulations that put forward the impact of the measures based on their interrelations with other modal choice factors. Our assessment leads to the conclusion that measures promoting public transport and car-pooling can reduce solo car driving between 7,2 % and 8,4 %. In contrast to our assumption, measures promoting public transport are less effective in central areas than in urban outskirts. Regarding measures promoting the use of bicycle, the findings suggest that the modal shift occurs from other modes rather than from car use. [less ▲]

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See detailEugène Catalan
Bair, Jacques ULg; Haesbroeck, Gentiane ULg

in Tangente (2014), 158

Eugène Catalan est né il y a exactement 200 ans ! Ses travaux mathématiques sont remarquables, tant par leur quantité (on dénombre environ 380 articles et 70 livres ou mémoires) que du point de vue de ... [more ▼]

Eugène Catalan est né il y a exactement 200 ans ! Ses travaux mathématiques sont remarquables, tant par leur quantité (on dénombre environ 380 articles et 70 livres ou mémoires) que du point de vue de leur qualité et de leur variété. En effet, son nom est encore aujourd'hui associé à de nombreux domaines des mathématiques. Citons notamment diverses conjectures fameuses sur les nombres ou équations, l'étude de nombres éponymes en combinatoire, l'introduction des polyèdres semi-réguliers ou des surfaces minimales en géométrie, le calcul d'intégrales multiples ou encore de séries en analyse. A l'occasion de cet anniversaire, nous mettons en évidence quelques éléments de sa biographie. [less ▲]

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See detailExploitation du concept de 'physical literacy' dans le cadre d'une séance d'ergonomie et de manutention
Laurent, Charlotte; Mouton, Alexandre ULg; Cloes, Marc ULg

in Revue de l'Education Physique (2014), 54(2), 43-53

Cet article présente une leçon d'éducation physique proposée à une classe de filles engagées dans une formation professionnelle en puériculture. Après une description du contexte d'enseignement, les ... [more ▼]

Cet article présente une leçon d'éducation physique proposée à une classe de filles engagées dans une formation professionnelle en puériculture. Après une description du contexte d'enseignement, les auteurs décrivent les contenus proposés aux élèves et illustrent les principes didactiques qui ont été appliqués dans cette séance au cours de laquelle la participation a été optimale en raison du sens donné aux activités. [less ▲]

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See detailCompost Pile Monitoring Using Different Approaches:GC-MS, E-nose and dynamic olfactometry
Gutierrez, M. C.; Chica, A. F.; Martin, M. A. et al

in Waste and Biomass Valorization (2014), 5(3), 469-479

The evaluation of odour emissions associated to the composting process is complex because these emissions depend on several factors such as the raw material to be composted, the different stages of the ... [more ▼]

The evaluation of odour emissions associated to the composting process is complex because these emissions depend on several factors such as the raw material to be composted, the different stages of the composting process, meteorological conditions, and others. For this reason, the aim of this paper is to compare complementary approaches to monitor odours. The odour source selected for this study is green waste compost at different maturity stages. The study site is a composting facility located in the south of Belgium. The compared approaches were: a portable e-nose developed by the Environmental Monitoring Research team (Arlon, Belgium) to monitor odorous emissions from the composting piles; chemical analyses performed in the laboratory using a GC–MS (manufactured by Thermo) to analyse volatile organic compounds which were collected by active sampling on Tenax TA sorbent simultaneously to the in situ e-nose measurements and olfactometric measurements to determine the odour concentration (ouE/m3) using the Odile olfactometer (Odotech). The portable e-nose was also used in the laboratory with compost odour samples collected in bags. The large numbers of data sets obtained were explored by statistical methods such as principal components analysis. The results obtained highlight the advantages of monitoring the composting process with these three approaches. Each approach gives different information about the composting process and the emissions generated. While the e-nose is capable of identifying some chemical family emissions and some activities such as turning steps, the GC–MS identifies each chemical compound emitted and dynamic olfactometry quantifies the odour concentration (ouE/m3) in relationship with these emissions. [less ▲]

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See detailLe principe de liberté tarifaire existe-t-il pour les compagnies d'assurances ? Oui, mais...
Wildemeersch, Jonathan ULg

in Revue luxembourgeoise de bancassurifinance (2014), (2), 59

L’arrêt rendu par la Cour de justice de l’Union européenne le 7 mars 2013 dans l’affaire C-577/11, DKV Belgium, s’inscrit dans le contexte particulier de l’encadrement par le législateur belge, dans la ... [more ▼]

L’arrêt rendu par la Cour de justice de l’Union européenne le 7 mars 2013 dans l’affaire C-577/11, DKV Belgium, s’inscrit dans le contexte particulier de l’encadrement par le législateur belge, dans la loi sur les contrats d’assurance terrestre (LCAT), des contrats d’assurance maladie . Il concerne plus spécifiquement l’article 138bis-4 de la loi belge, lequel règlemente les hausses tarifaires des contrats d’assurance maladie non liés à l’activité professionnelle. Dans un souci de protection du consommateur, le législateur a, en effet, choisi d’encadrer strictement les possibilités de hausses tarifaires de ce type de contrat. Interrogée à titre préjudiciel, la Cour est appelée à se prononcer sur la compatibilité de ce mécanisme avec le droit de l'Union. [less ▲]

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See detailA window on exoplanet dynamical histories: Rossiter-McLaughlin observations of WASP-13b and WASP-32b
Brothwell, R.D.; Watson, C.A.; Hébrard, G. et al

in Monthly Notices of the Royal Astronomical Society (2014), 440(4), 3392-3401

We present Rossiter-McLaughlin observations of WASP-13b and WASP-32b and determine the sky-projected angle between the normal of the planetary orbit and the stellar rotation axis (lambda). WASP-13b and ... [more ▼]

We present Rossiter-McLaughlin observations of WASP-13b and WASP-32b and determine the sky-projected angle between the normal of the planetary orbit and the stellar rotation axis (lambda). WASP-13b and WASP-32b both have prograde orbits and are consistent with alignment with measured sky-projected angles of lambda =8°^{+13}_{-12} and lambda =-2°^{+17}_{-19}, respectively. Both WASP-13 and WASP-32 have Teff < 6250 K, and therefore, these systems support the general trend that aligned planetary systems are preferentially found orbiting cool host stars. A Lomb-Scargle periodogram analysis was carried out on archival SuperWASP data for both systems. A statistically significant stellar rotation period detection (above 99.9 per cent confidence) was identified for the WASP-32 system with Prot = 11.6 ± 1.0 days. This rotation period is in agreement with the predicted stellar rotation period calculated from the stellar radius, R*, and vsin i if a stellar inclination of i* = 90° is assumed. With the determined rotation period, the true 3D angle between the stellar rotation axis and the planetary orbit, psi, was found to be psi = 11° ± 14°. We conclude with a discussion on the alignment of systems around cool host stars with Teff < 6150 K by calculating the tidal dissipation time-scale. We find that systems with short tidal dissipation time-scales are preferentially aligned and systems with long tidal dissipation time-scales have a broad range of obliquities. [less ▲]

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See detailRevascularisation versus medical treatment in patients with stable coronary artery disease: network meta-analysis.
Windecker, Stephan; Stortecky, Stefan; Stefanini, Giulio G. et al

in BMJ (Clinical research ed.) (2014), 348

OBJECTIVE: To investigate whether revascularisation improves prognosis compared with medical treatment among patients with stable coronary artery disease. DESIGN: Bayesian network meta-analyses to combine ... [more ▼]

OBJECTIVE: To investigate whether revascularisation improves prognosis compared with medical treatment among patients with stable coronary artery disease. DESIGN: Bayesian network meta-analyses to combine direct within trial comparisons between treatments with indirect evidence from other trials while maintaining randomisation. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: A strategy of initial medical treatment compared with revascularisation by coronary artery bypass grafting or Food and Drug Administration approved techniques for percutaneous revascularization: balloon angioplasty, bare metal stent, early generation paclitaxel eluting stent, sirolimus eluting stent, and zotarolimus eluting (Endeavor) stent, and new generation everolimus eluting stent, and zotarolimus eluting (Resolute) stent among patients with stable coronary artery disease. DATA SOURCES: Medline and Embase from 1980 to 2013 for randomised trials comparing medical treatment with revascularisation. MAIN OUTCOME MEASURE: All cause mortality. RESULTS: 100 trials in 93,553 patients with 262,090 patient years of follow-up were included. Coronary artery bypass grafting was associated with a survival benefit (rate ratio 0.80, 95% credibility interval 0.70 to 0.91) compared with medical treatment. New generation drug eluting stents (everolimus: 0.75, 0.59 to 0.96; zotarolimus (Resolute): 0.65, 0.42 to 1.00) but not balloon angioplasty (0.85, 0.68 to 1.04), bare metal stents (0.92, 0.79 to 1.05), or early generation drug eluting stents (paclitaxel: 0.92, 0.75 to 1.12; sirolimus: 0.91, 0.75 to 1.10; zotarolimus (Endeavor): 0.88, 0.69 to 1.10) were associated with improved survival compared with medical treatment. Coronary artery bypass grafting reduced the risk of myocardial infarction compared with medical treatment (0.79, 0.63 to 0.99), and everolimus eluting stents showed a trend towards a reduced risk of myocardial infarction (0.75, 0.55 to 1.01). The risk of subsequent revascularisation was noticeably reduced by coronary artery bypass grafting (0.16, 0.13 to 0.20) followed by new generation drug eluting stents (zotarolimus (Resolute): 0.26, 0.17 to 0.40; everolimus: 0.27, 0.21 to 0.35), early generation drug eluting stents (zotarolimus (Endeavor): 0.37, 0.28 to 0.50; sirolimus: 0.29, 0.24 to 0.36; paclitaxel: 0.44, 0.35 to 0.54), and bare metal stents (0.69, 0.59 to 0.81) compared with medical treatment. CONCLUSION: Among patients with stable coronary artery disease, coronary artery bypass grafting reduces the risk of death, myocardial infarction, and subsequent revascularisation compared with medical treatment. All stent based coronary revascularisation technologies reduce the need for revascularisation to a variable degree. Our results provide evidence for improved survival with new generation drug eluting stents but no other percutaneous revascularisation technology compared with medical treatment. [less ▲]

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See detailImpact de la double stigmatisation en oncogériatrie : Etat des lieux
Schroyen, Sarah ULg; Adam, Stéphane ULg; JERUSALEM, Guy ULg et al

in Gériatrie et Psychologie Neuropsychiatrie du Vieillissement (2014), 12(2), 131-8

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See detailStructural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride
Dilly, Sébastien ULg; Badarau, Eduard; Dufour, Fabien et al

in Journal of Molecular Structure (2014)

Reduction of symmetrical bis-isoquinolinium derivatives with sodium borohydride generates normally a mixture of three 1,2,3,4-tetrahydroisoquinoline stereoisomers. In a series of 8- isopropyl analogues ... [more ▼]

Reduction of symmetrical bis-isoquinolinium derivatives with sodium borohydride generates normally a mixture of three 1,2,3,4-tetrahydroisoquinoline stereoisomers. In a series of 8- isopropyl analogues, chiral resolution failed for the analogues with propyl and m-xylyl linkers since two and one peaks respectively were detected by HPLC. Further analysis by MS and CD of both peaks of the propyl analogue revealed that each peak corresponds to an enantiomer. Conformational analysis and X-ray cristallography showed a folded conformation of the propyl and m-xylyl analogues responsible for the observed stereoselectivity following the reduction step. Additional 1H NMR investigations confirm structural features detected by theoretical analysis. [less ▲]

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See detailMulti-scale aquifer characterization and groundwater flow model parameterization using direct push technologies
Rogiers, Bart; Vienken, Thomas; Gedeon, Matej et al

in Environmental Earth Sciences (2014)

Direct push (DP) technologies are typically used for cost-effective geotechnical characterization of unconsolidated soils and sediments. In more recent developments, DP technologies have been used for ... [more ▼]

Direct push (DP) technologies are typically used for cost-effective geotechnical characterization of unconsolidated soils and sediments. In more recent developments, DP technologies have been used for efficient hydraulic conductivity (K) characterization along vertical profiles with sampling resolutions of up to a few centimetres. Until date, however, only a limited number of studies document high-resolution in situ DP data for three-dimensional conceptual hydrogeological model development and groundwater flow model parameterization. This study demonstrates how DP technologies improve building of a conceptual hydrogeological model. We further evaluate the degree to which the DP-derived hydrogeological parameter K, measured across different spatial scales, improves performance of a regional groundwater flow model. The study area covers an area of ~60 km² with two overlying, mainly unconsolidated sand, aquifers separated by a 5-7 m thick highly heterogeneous clay layer (in north-eastern Belgium). The hydrostratigraphy was obtained from an analysis of cored boreholes and about 265 cone penetration tests (CPTs). The hydrogeological parameter K was derived from a combined analysis of core and CPT data and also from hydraulic direct push tests. A total of 50 three-dimensional realizations of K were generated using a non-stationary multivariate geostatistical approach. To preserve the measured K values in the stochastic realizations, the groundwater model Krealizations were conditioned on the borehole and direct push data. Optimization was performed to select the best performing model parameterization out of the 50 realizations. This model outperformed a previously developed reference model with homogeneous K fields for all hydrogeological layers. Comparison of particle tracking simulations, based either on the optimal heterogeneous or reference homogeneous groundwater model flow fields, demonstrate the impact DP-derived subsurface heterogeneity in K can have on groundwater flow and solute transport. We demonstrated that DP technologies, especially when calibrated with site-specific data, provide high-resolution 3D subsurface data for building more reliable conceptual models and increasing groundwater flow model performance. [less ▲]

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See detailSomething in the air
TAMBWE RAMAZANI, Willy ULg; BRASSEUR, Edmond ULg; JOHNSON, S et al

in Acta Clinica Belgica (2014), 69(S1), 28

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See detailAn unusual cervicalgy.
PIAZZA, Justine ULg; BRASSEUR, Edmond ULg; GHUYSEN, Alexandre ULg et al

in Acta Clinica Belgica (2014), 69(S1), 23

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See detailIn situ FTIR micro-spectroscopy to investigate polymeric fibers under supercritical carbon dioxide: CO2 sorption and swelling measurements
Champeau, Mathilde; Thomassin, Jean-Michel ULg; Jérôme, Christine ULg et al

in Journal of Supercritical Fluids (2014), 90

An original experimental set-up combining a FTIR (Fourier Transformed InfraRed) microscope with a high pressure cell has been built in order to analyze in situ and simultaneously the CO2 sorption and the ... [more ▼]

An original experimental set-up combining a FTIR (Fourier Transformed InfraRed) microscope with a high pressure cell has been built in order to analyze in situ and simultaneously the CO2 sorption and the polymer swelling of microscopic polymer samples, such as fibers, subjected to supercritical carbon dioxide. Thanks to this experimental set-up, we have determined as a function of the CO2 pressure (from 2 to 15 MPa) the CO2 sorption and the polymer swelling at T = 40 °C of four polymer samples, namely PEO (polyethylene oxide), PLLA (poly-l-lactide acid), PET (polyethylene terephtalate) and PP (polypropylene). The quantity of CO2 sorbed in all the studied polymers increases with pressure. PEO and PLLA display a significant level of CO2 sorption (20 and 25% respectively, at P = 15 MPa). However, we observe that a lower quantity of CO2 can be sorbed into PP and PET (7 and 8% respectively, at P = 15 MPa). Comparing their thermodynamic behaviors and their intrinsic properties, we emphasize that a high CO2 sorption can be reach if on one hand, the polymer is able to form specific interaction with CO2 in order to thermodynamically favor the presence of CO2 molecules inside the polymer and on the other, displays high chains mobility in the amorphous region. PLLA and PEO fulfilled these two requirements whereas only one property is fulfilled by PET (specific interaction with CO2) and PP (high chains mobility). Finally, we have found that for a given CO2 sorption, the resulting swelling of the polymer depends mainly on its crystallinity. [less ▲]

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See detailComputational homogenization of cellular materials
Nguyen, Van Dung ULg; Noels, Ludovic ULg

in International Journal of Solids and Structures (2014), 51(11-12), 2183-2203

In this work we propose to study the behavior of cellular materials using a second–order multi–scale computational homogenization approach. During the macroscopic loading, micro-buckling of thin ... [more ▼]

In this work we propose to study the behavior of cellular materials using a second–order multi–scale computational homogenization approach. During the macroscopic loading, micro-buckling of thin components, such as cell walls or cell struts, can occur. Even if the behavior of the materials of which the micro–structure is made remains elliptic, the homogenized behavior can lose its ellipticity. In that case, a localization band is formed and propagates at the macro–scale. When the localization occurs, the assumption of local action in the standard approach, for which the stress state on a material point depends only on the strain state at that point, is no–longer suitable, which motivates the use of the second-order multi–scale computational homogenization scheme. At the macro–scale of this scheme, the discontinuous Galerkin method is chosen to solve the Mindlin strain gradient continuum. At the microscopic scale, the classical finite element resolutions of representative volume elements are considered. Since the meshes generated from cellular materials exhibit voids on the boundaries and are not conforming in general, the periodic boundary conditions are reformulated and are enforced by a polynomial interpolation method. With the presence of instability phenomena at both scales, the arc–length path following technique is adopted to solve both macroscopic and microscopic problems. [less ▲]

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See detailLiege City Parade 2013: evaluation of the preventive plan.
BRASSEUR, Edmond ULg; MASTRODICASA, Adrian ULg; GILLARD, Florence ULg et al

in Acta Clinica Belgica (2014), 69(S1), 15

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See detailLe “Pacte budgétaire” européen, quelle influence sur les finances publiques belges ?
Uhoda, Maxime ULg

in Pyramides : Revue du Laboratoire d’Etudes et de Recherches en Administration Publique (2014), 25(25 - 2014/1), 87-122

La contribution se propose d’étudier les nouvelles obligations qui découlent du « pacte budgétaire » contenu dans le « Traité sur la stabilité, la coordination et la gouvernance au sein de l'union ... [more ▼]

La contribution se propose d’étudier les nouvelles obligations qui découlent du « pacte budgétaire » contenu dans le « Traité sur la stabilité, la coordination et la gouvernance au sein de l'union économique et monétaire ». Il s’agit d’un traité intergouvernemental signé par vingt-cinq États membres de l’Union européenne (à l’exclusion du Royaume-Uni et de la République Tchèque) dont le contenu est appelé à être intégré dans le cadre juridique de l’Union avant le 1er janvier 2018. Dans le contexte d’une double dynamique que connaissent actuellement les finances publiques des États membres de la zone euro – d’un côté, la construction de l’Union économique et monétaire européenne et de l’autre côté, dans certains pays, des phénomènes de décentralisation fiscale – le resserrement de la discipline budgétaire européenne semble traduire une tendance vers l’émergence de nouveaux principes constitutionnels de type financier. En Belgique, les modalités concrètes de transposition de ces nouvelles obligations – à savoir, l’incorporation en droit belge d’une règle d’équilibre budgétaire définie en termes structurels, l’instauration d’un « mécanisme de correction interne » et la mise en place d’une autorité de contrôle budgétaire indépendante, passent par la signature d’un accord de coopération et de nouvelles missions confiées à la section « Besoins de financement des pouvoirs publics » du Conseil supérieur des finances. [less ▲]

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See detailA quick high before immersion into the deep blue: the fall of Icarus revised.
LOPEZ RODRIGUEZ, Alicia ULg; BRASSEUR, Edmond ULg; GHUYSEN, Alexandre ULg et al

in Acta Clinica Belgica (2014), 69(S1), 21

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See detailIsocinetisme et sport de haut niveau : applications à la traumatologie du sport
Barthelemy, Yannick; Kaux, Jean-François ULg; Ferret, Jean-Marcel

in Movement & Sport Sciences – Science & Motricité (2014), 85

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See detailCrise ou catharsis ?
Vanmeerbeek, Marc ULg

in Exercer (2014), 113(Editorial), 99

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See detailBayesian penalized smoothing approaches in models specified using affine differential equations with unknown error distributions
Jaeger, Jonathan ULg; Lambert, Philippe ULg

in Journal of Applied Statistics (2014), 41(12), 2709-2726

A full Bayesian approach based on ODE-penalized B-splines and penalized Gaussian mixture is proposed to jointly estimate ODE-parameters, state function and error distribution from the observation of some ... [more ▼]

A full Bayesian approach based on ODE-penalized B-splines and penalized Gaussian mixture is proposed to jointly estimate ODE-parameters, state function and error distribution from the observation of some state functions involved in systems of affine differential equations. Simulations inspired by pharmacokinetic studies show that the proposed method provides comparable results to the method based on the standard ODE-penalized B-spline approach (i.e. with the Gaussian error distribution assumption) and outperforms the standard ODE-penalized B-splines when the distribution is not Gaussian. This methodology is illustrated on the Theophylline dataset. [less ▲]

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See detailPhysical controls on the storage of methane in landfast sea ice
Zhou, Jiayun ULg; Tison, J.-L.; Carnat, G. et al

in The Cryosphere (2014), 8(3), 1019-1029

We report on methane (CH4) dynamics in landfast sea ice, brine and under-ice seawater at Barrow in 2009. The CH4 concentrations in under-ice water ranged between 25.9 and 116.4 nmol L-1sw, indicating a ... [more ▼]

We report on methane (CH4) dynamics in landfast sea ice, brine and under-ice seawater at Barrow in 2009. The CH4 concentrations in under-ice water ranged between 25.9 and 116.4 nmol L-1sw, indicating a supersaturation of 700 to 3100 % relative to the atmosphere. In comparison, the CH4 concentrations in sea ice, ranged between 3.4 and 17.2 nmol L-1ice, and the deduced CH4 concentrations in brine, between 13.2 and 677.7 nmol L-1brine. We investigated on the processes explaining the difference in CH4 concentrations between sea ice, brine and the under-ice water, and suggest that biological controls on the storage of CH4 in ice was minor in comparison to the physical controls. Two physical processes regulated the storage of CH4 in our landfast ice samples: bubble formation within the ice and sea ice permeability. Gas bubble formation from solubility changes had favoured the accumulation of CH4 in the ice at the beginning of ice growth. CH4 retention in sea ice was then twice as efficient as that of salt; this also explains the overall higher CH4 concentrations in brine than in the under-ice water. As sea ice thickened, gas bubble formation became less efficient, CH4 was then mainly trapped in the dissolved state. The increase of sea ice permeability during ice melt marked the end of CH4 storage. [less ▲]

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See detailSynthèse bibliographique sur la mobilité des éléments traces dans les sols et l’utilisation de la stabilisation physico-chimique comme technique de gestion in situ des sites contaminés
Liénard, Amandine ULg; Colinet, Gilles ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2014), 18(2), 273-289

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the ... [more ▼]

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the mobility of contaminants in soils and what are the remediation practices based upon physico-chemical stabilization? This technique is an in situ remediation which aims at limiting the dispersion of metals in the environment by use of soil conditioners and amendments in contaminated sites. First of all, we reviewed the concepts of mobility of trace elements and their indicators. Then, we compiled the different kinds of amendments applied to stabilize contaminants in soils and the processes involved. [less ▲]

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See detailAntemortem Diagnosis of Multicentric Lymphoblastic Lymphoma, Lymphoid Leukemia, and Inclusion Body Disease in a Boa Constrictor (Boa constrictor imperator)
Schilliger, Lionel; Rossfelder, Aurore; Bonwitt, Jesse et al

in Journal of Herpetological Medicine and Surgery (2014), 24(1-2), 11-19

A 1.85-kg, 6-yr-old, captive-bred, male boa constrictor (Boa constrictor imperator) was presented for lethargy, anorexia, postural abnormalities, and had an elongated mass on its ventrum, 20 cm distal to ... [more ▼]

A 1.85-kg, 6-yr-old, captive-bred, male boa constrictor (Boa constrictor imperator) was presented for lethargy, anorexia, postural abnormalities, and had an elongated mass on its ventrum, 20 cm distal to the snout. Clinical examination revealed a firm, nonmobile coelomic mass (4 cm × 2 cm) and loss of the righting reflex. Hematology showed a significant increase in white blood cells, lymphocytosis, and anemia. Cytologic examination of the blood smears showed the presence of lymphoid leukemia and eosinophilic intracytoplasmic inclusions consistent with inclusion body disease (IBD). Hyperphosphatemia was suggestive of renal failure. Radiography and ultrasound revealed a soft tissue mass at the level of the thymus proximal to, and distinct from, the heart. Cytology and postmortem histopathology confirmed the presence of a multicentric lymphoblastic lymphoma, lymphoid leukemia, and IBD. It remains unclear whether the neoplasms began their proliferation within the bone marrow or whether leukemia was a feature of disseminated, end-stage lymphoma. [less ▲]

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See detailEvaluation of the Economic Statistical Design of the Multivariate T2 Control Chart with Multiple Variable Sampling Intervals Scheme: NSGA-II Approach
Faraz, Alireza ULg; Seif, Asghar; Sadeghifar

in Journal of Statistical Computation & Simulation (2014)

The economic and statistical merits of a multiple variable sampling intervals (MVSI) scheme are studied. The problem is formulated as a double-objective optimization problem with the adjusted average time ... [more ▼]

The economic and statistical merits of a multiple variable sampling intervals (MVSI) scheme are studied. The problem is formulated as a double-objective optimization problem with the adjusted average time to signal as the statistical objective and the expected cost per hour as the economic objective. Bai and Lee’s ‎[2] economic model is considered. Then we find the Pareto-optimal designs in which the two objectives are minimized simultaneously by using the non-dominated sorting genetic algorithm. Through an illustrative example, the advantages of the proposed approach is shown by providing a list of viable optimal solutions and graphical representations, which indicate the advantage of flexibility and adaptability of our approach. [less ▲]

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See detailThe composition of cuticular compounds indicates body parts, sex and age in the model butterfly Bicyclus anynana (Lepidoptera)
Heuskin, Stéphanie ULg; Vanderplanck, Maryse; Bacquet, Paul et al

in Frontiers in Ecology and Evolution (2014), 2:37

Chemical communication in insects’ sexual interactions is well-known to involve olfaction of volatile compounds called sex pheromones. In theory, sexual chemical communication may also involve chemicals ... [more ▼]

Chemical communication in insects’ sexual interactions is well-known to involve olfaction of volatile compounds called sex pheromones. In theory, sexual chemical communication may also involve chemicals with low or no volatility exchanged during precopulatory gustatory contacts. Yet, knowledge on this latter type of chemicals is so far mostly restricted to the Drosophila fly model. Here we provide the most comprehensive characterization to date of the cuticular chemical profile, including both volatile and non-volatile compounds, of a model butterfly, Bicyclus anynana. First, we characterized the body distribution of 103 cuticular lipids, mostly alkanes and methyl-branched alkanes, by gas chromatography coupled to mass spectrometry (GC-MS). Second, we developed a multivariate statistical approach to cope with such complex chemical profiles and showed that variation in the presence or abundance of a subset of the cuticular lipids indicated body parts, and traits involved in B. anynana mate choice, namely sex and age. Third, we identified the chemical structure of the 20 most indicative compounds, which were on average more abundant (1346.4 ± 1994.6 ng; mean ± SD) than other, likely less indicative, compounds (225.9 ± 507.2 ng; mean ± SD). Fourth, we showed that wings and legs displayed most of the chemical information found on the entire body of the butterflies. Fifth, we showed that non-random gustatory contacts occurred between specific male and female body parts during courtship. The body parts mostly touched by the conspecific displayed the largest between-sex differentiation in cuticular composition. Altogether, the large diversity of cuticular lipids in B. anynana, which exceeds the one of Drosophila flies, and its non-random distribution and evaluation across individuals, together suggest that gustatory information is likely exchanged during sexual interactions in Lepidoptera. [less ▲]

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See detailTwo Scenarios for Quantum Multifractality Breakdown
Dubertrand, Rémy ULg; Garcia-Mata, Ignacio; Georgeot, Bertrand et al

in Physical Review Letters (2014), 112

We expose two scenarios for the breakdown of quantum multifractality under the effect of perturbations. In the first scenario, multifractality survives below a certain scale of the quantum fluctuations ... [more ▼]

We expose two scenarios for the breakdown of quantum multifractality under the effect of perturbations. In the first scenario, multifractality survives below a certain scale of the quantum fluctuations. In the other one, the fluctuations of the wave functions are changed at every scale and each multifractal dimension smoothly goes to the ergodic value. We use as generic examples a one-dimensional dynamical system and the three-dimensional Anderson model at the metal-insulator transition. Based on our results, we conjecture that the sensitivity of quantum multifractality to perturbation is universal in the sense that it follows one of these two scenarios depending on the perturbation. We also discuss the experimental implications. [less ▲]

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See detailPosterior Cingulate Cortex-Related Co-Activation Patterns: A Resting State fMRI Study in Propofol-Induced Loss of Consciousness
Amico, Enrico ULg; Gomez, Francisco; Di Perri, Carol et al

in PLoS ONE (2014), 9

Background: Recent studies have been shown that functional connectivity of cerebral areas is not a static phenomenon, but exhibits spontaneous fluctuations over time. There is evidence that fluctuating ... [more ▼]

Background: Recent studies have been shown that functional connectivity of cerebral areas is not a static phenomenon, but exhibits spontaneous fluctuations over time. There is evidence that fluctuating connectivity is an intrinsic phenomenon of brain dynamics that persists during anesthesia. Lately, point process analysis applied on functional data has revealed that much of the information regarding brain connectivity is contained in a fraction of critical time points of a resting state dataset. In the present study we want to extend this methodology for the investigation of resting state fMRI spatial pattern changes during propofol-induced modulation of consciousness, with the aim of extracting new insights on brain networks consciousness-dependent fluctuations. Methods: Resting-state fMRI volumes on 18 healthy subjects were acquired in four clinical states during propofol injection: wakefulness, sedation, unconsciousness, and recovery. The dataset was reduced to a spatio-temporal point process by selecting time points in the Posterior Cingulate Cortex (PCC) at which the signal is higher than a given threshold (i.e., BOLD intensity above 1 standard deviation). Spatial clustering on the PCC time frames extracted was then performed (number of clusters = 8), to obtain 8 different PCC co-activation patterns (CAPs) for each level of consciousness. Results: The current analysis shows that the core of the PCC-CAPs throughout consciousness modulation seems to be preserved. Nonetheless, this methodology enables to differentiate region-specific propofol-induced reductions in PCC-CAPs, some of them already present in the functional connectivity literature (e.g., disconnections of the prefrontal cortex, thalamus, auditory cortex), some others new (e.g., reduced co-activation in motor cortex and visual area). Conclusion: In conclusion, our results indicate that the employed methodology can help in improving and refining the characterization of local functional changes in the brain associated to propofol-induced modulation of consciousness. [less ▲]

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See detailTwo Scenarios for Quantum Multifractality Breakdown
Dubertrand, Rémy ULg; Garcia-Mata, Ignacio; Georgeot, Bertrand et al

in Physical Review Letters (2014), 112

We expose two scenarios for the breakdown of quantum multifractality under the effect of perturbations. In the first scenario, multifractality survives below a certain scale of the quantum fluctuations ... [more ▼]

We expose two scenarios for the breakdown of quantum multifractality under the effect of perturbations. In the first scenario, multifractality survives below a certain scale of the quantum fluctuations. In the other one, the fluctuations of the wave functions are changed at every scale and each multifractal dimension smoothly goes to the ergodic value. We use as generic examples a one-dimensional dynamical system and the three-dimensional Anderson model at the metal-insulator transition. Based on our results, we conjecture that the sensitivity of quantum multifractality to perturbation is universal in the sense that it follows one of these two scenarios depending on the perturbation. We also discuss the experimental implications. [less ▲]

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See detailPortrait et imaginaire photographique. Cliché et anti-cliché du Nouveau Roman.
Lorent, Fanny ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2014), 14

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See detailReading Cadaveric Decomposition Chemistry with a New Pair of Glasses
Stefanuto, Pierre-Hugues ULg; Perrault, Katelynn; Stadler, Sonja et al

in CHEMPLUSCHEM (2014)

Smell it out! Thermal desorption has been coupled with comprehensive two-dimensional gas chromatography time of-flight mass spectrometry for the characterization of a cadaveric volatile organic compound ... [more ▼]

Smell it out! Thermal desorption has been coupled with comprehensive two-dimensional gas chromatography time of-flight mass spectrometry for the characterization of a cadaveric volatile organic compound mixture producedduring the active decay stage (see figure). The combined use of the Fisher ratio and principal component analysis provided further characterization of the chemical profile of decomposition. [less ▲]

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See detailGeometric interpretation of a non-linear beam finite element on the Lie group SE(3)
Sonneville, Valentin ULg; Cardona, Alberto; Bruls, Olivier ULg

in Archive of Mechanical Engineering (2014), 61(2), 305-329

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See detailJustitie hervormen: leren uit de intrede van HR-adviseurs
Delvaux, David ULg; Schoenaers, Frédéric ULg

in Orde van de dag (2014), 66

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See detailSpatial augmented reality in collaborative design training : articulation between I-space, We-space and Space-between
Ben Rajeb, Samia ULg; Leclercq, Pierre ULg

in Lecture Notes in Computer Science (2014), LNCS 8526 / vol 2(part 2), 343-353

This paper analyses the use of augmented reality in advanced project-based training in design. Our study considers how augmented environments can contribute to this type of group training : what types of ... [more ▼]

This paper analyses the use of augmented reality in advanced project-based training in design. Our study considers how augmented environments can contribute to this type of group training : what types of interaction spaces constitute these new learning environments and how are these spaces constructed so as to promote collective reflection ? [less ▲]

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See detailInfluence of the cardiac cycle on time-intensity curves using multislice dynamic magnetic resonance perfusion
NCHIMI LONGANG, Alain ULg; MANCINI, Isabelle; BROUSSAUD, Thomas K. Y.

in International Journal of Cardiovascular Imaging (The) (2014), 30

Flow and pressure variations cause potential changes in magnetic resonance imaging (MRI) signal intensity across the cardiac cycle. Nevertheless, cardiac dynamic contrast-enhanced (perfusion) MRI is ... [more ▼]

Flow and pressure variations cause potential changes in magnetic resonance imaging (MRI) signal intensity across the cardiac cycle. Nevertheless, cardiac dynamic contrast-enhanced (perfusion) MRI is performed and analyzed regardless of the cardiac phase. We investigate whether the cardiac phase impacts myocardial and left ventricle (LV) cavity time intensity curves (TICs) at rest and during vasodilatation. Fifteen healthy volunteers (seven females, eight males; mean age: 32.5 ± 9.3 years; age range: 19–49 years) were included in this prospective study. They underwent four separate short-axis multislice (apical, mid and basal) LV perfusion MRI, with different electrocardiogram-triggering during normal vasotone and adenosine-stress. TIC parameters were extracted from the myocardium and the LV cavity. General linear mixed model analyses were used to evaluate their variability according to vasotone, cardiac phase and slice-position. Maximal enhancement and normalized Steepest slopes were higher at stress than at rest (p values <0.001). A similar trend towards higher inflow was shown on systole versus diastole in the LV cavity and diastole versus systole in the myocardium (p < 0.05).These TIC parameters were slice-position dependent, as the inflow decreased from the base to the apex in the LV, and peaked on the mid-slice for the myocardium. There are significant variability of both the LV and the myocardial TICs, with respect to the cardiac cycle phase and the slice position where imaging actually takes place. These appeal to measurement standardization for a better intra- and inter-study reproducibility. [less ▲]

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See detailSpatial optimization in perfusion bioreactors improves bone tissue-engineered construct quality attributes
Papantoniou, Ioannis; Guyot, Yann ULg; Sonnaert, Maarten et al

in Biotechnology and Bioengineering (2014)

Perfusion bioreactors have shown great promise for tissue engineering applications providing a homogeneous and consistent distribution of nutrients and flow-induced shear stresses throughout tissue ... [more ▼]

Perfusion bioreactors have shown great promise for tissue engineering applications providing a homogeneous and consistent distribution of nutrients and flow-induced shear stresses throughout tissue-engineered constructs. However, non uniform fluid-flow profiles found in the perfusion chamber entrance region have been shown to affect tissue-engineered construct quality characteristics during culture. In this study a whole perfusion and construct, three dimensional (3D) computational fluid dynamics approach was used in order to optimize a critical design parameter such as the location of the regular pore scaffolds within the perfusion bioreactor chamber. Computational studies were coupled to bioreactor experiments for a case-study flow rate. Two cases were compared in the first instance seeded scaffolds were positioned immediately after the perfusion chamber inlet while a second group was positioned at the computationally determined optimum distance were a steady state flow profile had been reached. Experimental data showed that scaffold location affected significantly cell content and neo-tissue distribution, as determined and quantified by contrast enhanced nanoCT, within the constructs both at 14 and 21 days of culture. However gene expression level of osteopontin and osteocalcin was not affected by the scaffold location. This study demonstrates that the bioreactor chamber environment, incorporating a scaffold and its location within it, affects the flow patterns within the pores throughout the scaffold requiring therefore dedicated optimization that can lead to bone tissue engineered constructs with improved quality attributes [less ▲]

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See detailSocial Security and Economic Integration
Artige, Lionel ULg; Dedry, Antoine ULg; Pestieau, Pierre ULg

in Economics Letters (2014), 123(June), 318-322

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See detailLe Portrait photographique d'écrivain
Bertrand, Jean-Pierre ULg; Durand, Pascal ULg; Lavaud, Martine

in COnTEXTES : Revue de Sociologie de la Littérature (2014), 14

Il en va des phénomènes omniprésents comme des évidences : ils passent volontiers inaperçus quand ils ne sont pas reçus comme procédant d’une nature des choses plutôt que d’une émergence historique et ... [more ▼]

Il en va des phénomènes omniprésents comme des évidences : ils passent volontiers inaperçus quand ils ne sont pas reçus comme procédant d’une nature des choses plutôt que d’une émergence historique et sociale. Vitrines de libraires, quatrièmes de couverture, affiches publicitaires, catalogues d’éditeur, manuels scolaires, monographies illustrées, journaux, magazines, émissions de télévision, documentaires, vidéos continuent d’enfoncer jour après jour dans notre œil l’évidence aveuglante que l’écrivain a un visage. Il n’en a pas toujours été ainsi et c’est bien en s’en avisant que l’on peut se mettre en condition de prendre la mesure des effets que la photographie, après d’autres formes de représentation iconographique, puis en concurrence avec celles-ci, a exercés non seulement sur la mise en image de la littérature et la visibilité de ceux qui la produisent, mais encore sur leur commune définition sociale après 1840. C’est dans cet esprit général, sensible aux modalités matérielles de l’histoire des représentations ainsi qu’aux implications épistémologiques du portrait photographique d’écrivain, que s’inscrivent les contributions réunies à l’enseigne de la revue Contextes. Elles proviennent de deux journées d’études qui se sont tenues à l’Université de Liège les 6 et 7 juin 2013 en vue d’éclairer sous différents aspects l’histoire des formes, des supports et des usages du portrait photographique d’écrivain de la fin des années 1830 à l’époque contemporaine — du romantisme au Nouveau Roman ou encore de Balzac à Houellebecq. Conformément à l’objet étudié, l’approche développée se veut résolument transdisciplinaire. Historiens de l’art et de la photographie rappellent utilement les conditions de naissance et de développement exponentiel d’un genre ayant bousculé l’ordre des représentations et les esthétiques. Historiens et sociologues de la littérature font ressortir les liens établis entre portrait photographique et auteurs photographiés, avec les implications que le médium a occasionnées durablement dans l’imaginaire littéraire. Sémioticiens et spécialistes des sciences du langage mettent en œuvre leur outillage descriptif sur la matérialité et la discursivité du cliché. Avec cela de commun en ligne de mire : à quoi tient la littérarité d’un portrait photographique d’écrivain ? A cette question, le dossier apporte quelques éléments de réponse en proposant un recadrage et un décadrage. Recadrage de l’image elle-même au sein des configurations auxquelles elle participe. Décadrage du portrait en direction des effets de contexte et de support qui sont inducteurs de sa signification. SOMMAIRE Martine LAVAUD (Paris IV), « Envisager l’histoire littéraire. Pour une épistémologie du portrait photographique d’écrivain » Pascal DURAND (ULg), « De Nadar à Dornac. Hexis corporelle et figuration photographique des écrivains » Jean-Pierre BERTRAND (ULg), « Esquisse d’un protocole de lecture du portrait photographique d’écrivain » Marc-Emmanuel MÉLON (ULg), Portrait de l’écrivain absorbé. Une allégorie photographique » Adeline WRONA (Celsa, Université Paris Sorbonne), « Le portrait-carte, de la photographie au journal. Le marché périodique du portrait d’écrivain » Hélène VÉDRINE (Université Paris Sorbonne), « Portraits de masques et de fantômes. Le portrait photographique dans le livre (1860-1930) » Bernard VOUILLOUX (Université Paris Sorbonne), « Une collection d’unica : les livres à portraits d’Edmond de Goncourt » François PROVENZANO (ULg), « Portrait photographique d’écrivain et newsmagazine. Pour une approche rhétorique de l’événementialité du littéraire » Fanny LORENT (ULg), « Portrait et imaginaire photographique. Cliché et anti-cliché du Nouveau Roman » Maria Giulia DONDERO (FNRS/ULg), « Les approches sémiotiques du portrait photographique. De l’identité à l’“air” » Jérôme MEIZOZ (Université de Lausanne), « Portrait photographique et présentation de soi. Cendrars, Houellebecq » [less ▲]

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See detailL- and V-curves for Optimal Smoothing
Frasso, Gianluca ULg; Eilers, Paul H. C.

in Statistical Modelling : An International Journal (2014)

The L-curve is a tool for the selection of the regularization parameter in ill-posed inverse problems. It is a parametric plot of the size of the residuals vs that of the penalty. The corner of the L ... [more ▼]

The L-curve is a tool for the selection of the regularization parameter in ill-posed inverse problems. It is a parametric plot of the size of the residuals vs that of the penalty. The corner of the L indicates the right amount of regularization. In the context of smoothing the L-curve is easy to compute and works surprisingly well, even for data with correlated noise. We present the theoretical background and applications to real data together with an alternative criterion for finding the corner automatically. We introduce as simplification, the V-curve, which replaces finding the corner of the L-curve by locating a minimum. [less ▲]

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See detailCorporéité et émotions dans les phénoménologies asubjectives de Sartre et de Patocka
Zincq, Aurélien ULg

in Etudes Sartriennes (2014), 17

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See detailRensch’s rule and sexual dimorphism in salamanders: patterns and potential processes
Colleoni, E.; Denoël, Mathieu ULg; Padoa-Schioppa, E. et al

in Journal of Zoology (2014), 293(3), 143-151

Body size is influenced by the interaction of multiple forces, whose effects can determine the occurrence of sexual size dimorphism (SSD). Rensch's rule is the increase of SSD with body size in taxa where ... [more ▼]

Body size is influenced by the interaction of multiple forces, whose effects can determine the occurrence of sexual size dimorphism (SSD). Rensch's rule is the increase of SSD with body size in taxa where males are the largest sex, and the opposite pattern in female-biased SSD taxa. This pattern was detected in many animal groups, but contrasting results were also highlighted. This study evaluated the existence of Rensch's patterns for body size and for the number of caudal vertebrae in salamandrid caudate amphibians. Furthermore, we tested the support of alternative hypotheses on processes that may determine allometric patterns: sexual selection, fecundity selection and constraining selection by performing separate analyses on species with male- and female-biased SSD. We used the literature and original data to gather information on body size and number of caudal vertebrae in 52 species of salamandrids over four continents. We then tested the support of the three hypotheses using a phylogenetic approach. Rensch's rule was valid for body size in salamanders only for species with male-biased dimorphism. No allometric relationships were detected by analyses on all the species, or by analyses on female-biased SSD species. Analyses performed on the number of caudal vertebrae showed no significant patterns. Our study supports the role of sexual selection in promoting positive allometry for body size in male-biased SSD species, whereas the alternative hypotheses were not supported by our data. These results highlight the importance of distinguishing male- and female-biased species as different evolutionary pressures and constraints may be at the basis of evolution of SSD in these groups. [less ▲]

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See detailLaTeX, un peu, beaucoup (4. Les "équations" et leurs styles)
Dupont, Pascal ULg

in Losanges (2014)

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See detailIs Contact Between Conspecifics Involved in the Cohesion of Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) Aggregations?
Durieux, Delphine ULg; Fassotte, Bérénice ULg; Fischer, Christophe ULg et al

in Journal of Insect Behavior (2014), 27(1), 1-13

The multicolored Asian ladybeetle, Harmonia axyridis (Pallas), exhibits a gregarious behavior during unfavorable winter conditions. Although this behavior is currently described as a phenomenon occurring ... [more ▼]

The multicolored Asian ladybeetle, Harmonia axyridis (Pallas), exhibits a gregarious behavior during unfavorable winter conditions. Although this behavior is currently described as a phenomenon occurring only during winter, aggregations can also be observed outside overwintering conditions. However, the substrate markings previously highlighted as being involved in the wintry aggregation of this exotic species do not seem to be used by non-overwintering individuals to aggregate. This fact suggests then that other cues are responsible for the induction of this behavior. In this work, we have tested the hypothesis that direct contact between non-overwintering individuals stimulates the establishment of clusters. Binary choice experiments highlighted the involvement of elytral cuticular compounds in this phenomenon. Chromatographic analyses showed that the active extracts contained mainly hydrocarbons, including saturated, mono-unsaturated, and di-unsaturated homologues. Physical contact also seems to be involved in the non-overwintering aggregative behavior of H. axyridis, but to a lesser extent than these natural compounds. These findings could eventually be used to develop new control methods of these pest populations and so, reduce the adverse impacts it causes on biodiversity. [less ▲]

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See detailMaitriser le temps? L'accélération du traitement judiciaire du divorce en France et en Belgique
Bastard, Benoit; Delvaux, David ULg; Mouhanna, Christian et al

in Temporalités : Productions, Usages, Figures : Revue de Sciences Sociales et Humaines (2014), 19

Cet article aborde la question du temps dans l’institution judiciaire en prenant pour objet le contentieux familial. En considérant la dimension temporelle du règlement des conflits qui émergent lors des ... [more ▼]

Cet article aborde la question du temps dans l’institution judiciaire en prenant pour objet le contentieux familial. En considérant la dimension temporelle du règlement des conflits qui émergent lors des ruptures d’union, il met en évidence le changement radical de la vision du temps qui a touché le monde de la justice civile dans les dernières décennies. Le mouvement d’accélération qui touche l’ensemble de l’institution judiciaire se trouve redoublé dans ce champ par l’urgence qu’impose la réaction face à un contentieux de masse : il s’agit de répondre sans délais aux conflits familiaux, selon des modalités adaptées aux besoins des intéressés. L’étude s’appuie sur une enquête réalisée dans cinq juridictions, en France et en Belgique. Dans ces deux pays, les dernières réformes intervenues ont eu pour projet de hâter les procédures de divorce. Dans la pratique, différentes modalités de l’accélération du traitement judiciaire sont observées. En France, le juge aux affaires familiales est un acteur central qui traite l’ensemble des ruptures de couple soumises à la justice. Les JAF font tout pour accélérer les décisions, en s’appuyant autant que faire se peut sur l’accord des parties et en cherchant à contrôler les avocats. En Belgique, l’accélération est particulièrement apparente s’agissant du procès en divorce, mais les décisions sur les effets accessoires de la séparation sont renvoyées à différentes instances ayant leur propre temporalité. Par-delà ces différences, la comparaison suggère que l’accélération du traitement du contentieux de la famille résulte de la coprésence des deux tendances majeures observées, la managérialisation de la justice et le renvoi des décisions relatives à la famille vers les intéressés eux-mêmes. L’accélération du traitement judiciaire du divorce n’est cependant pas sans conséquence : en particulier, elle rend plus apparente la disjonction du temps du procès et de celui que vivent les conjoints en rupture. [less ▲]

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See detailComparison of centralized, distributed and hierarchical model predictive control schemes for electromechanical oscillations damping in large-scale power systems
Wang, Da ULg; Glavic, Mevludin ULg; Wehenkel, Louis ULg

in International Journal of Electrical Power & Energy Systems (2014), 58

The paper investigates the feasibility of applying Model Predictive Control (MPC) as a viable strategy to damp wide-area electromechanical oscillations in large-scale power systems. First a fully ... [more ▼]

The paper investigates the feasibility of applying Model Predictive Control (MPC) as a viable strategy to damp wide-area electromechanical oscillations in large-scale power systems. First a fully centralized MPC scheme is considered, and its performances are evaluated first in ideal conditions and then by considering state estimation errors and communication delays. This scheme is further extended into a distributed scheme with the aim of making it more viable for very large-scale or multi-area systems. Finally, a robust hierarchical multi-area MPC scheme is proposed, introducing a second layer of MPC based controllers at the level of individual power plants and transmission lines. Simulations are carried out using a 70-bus test system. The results reveal all three MPC schemes as viable solutions to supplement existing controllers in order to improve the system performance in terms of damping. The hierarchical scheme is the one combining the best performances in nominal conditions and the best robustness with respect to partial component failures and various modeling and measurement errors. [less ▲]

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See detailElectrical Source Imaging in cortical malformation-related epilepsy : a prospective EEG-SEEG concordance study
RIKIR, Estelle ULg; KOESSLER, Laurent; GAVARET, Martine et al

in Epilepsia (2014), 55(6), 918-932

OBJECTIVE: Delineating the epileptogenic zone (EZ) in refractory epilepsy related to malformations of cortical development (MCD) often requires intracranial EEG recordings, especially in cases of negative ... [more ▼]

OBJECTIVE: Delineating the epileptogenic zone (EZ) in refractory epilepsy related to malformations of cortical development (MCD) often requires intracranial EEG recordings, especially in cases of negative MRI or discordant MRI and video-EEG findings. It is therefore crucial to promote the development of non-invasive methods such as electrical source imaging (ESI). We aimed to (i) analyze the localization concordance of ESI derived from interictal discharges and EZ estimated by stereo-electroencephalography (SEEG), (ii) compare the concordance of ESI, MRI and electro-clinical correlations (ECC) with SEEG-EZ, and (iii) assess ESI added value in the EZ localization. METHODS: We prospectively analyzed 28 consecutive patients undergoing presurgical investigation for MCD-related refractory epilepsy in 2009-2012. ESI derived from 64-channel scalp EEG was interpreted blinded to- and subsequently compared with SEEG estimated ΕZ. Anatomical concordance of ESI with SEEG-ΕZ was compared to that of video-EEG and MRI. We further assessed ESI added value to ECC and MRI. RESULTS: Twelve (43%) patients had temporal and 16 (57%) extratemporal epilepsy. MRI was negative in 11 (39%) and revealed a cortical malformation in 17 (61%). ESI was fully concordant with the EZ in ten (36%) and partly concordant in 15 (53%). ECC presented a full and partial concordance with EZ in 11% and 82% of cases respectively and MRI in 11% and 46% respectively. Of 11 patients with negative MRI, ESI was fully concordant with the EZ in seven (64%), partly concordant in four (36%). ESI correctly confirmed, restricted or added localizations to ECC and MRI in 12 of 28 patients (43%) and in eight of 11 patients (73%) with negative MRI. SIGNIFICANCE: ESI contributes to estimate the EZ in MCD-related epilepsy. The added value of ESI to ECC is particularly high in patients with MCD and negative MRI, who represent the most challenging cases for epilepsy surgery. [less ▲]

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See detailIs conspecific substrate marking a long-term external memory of previously colonized overwintering sites in Harmonia axyridis?
Durieux, Delphine ULg; Fassotte, Bérénice ULg; Vanderplanck, Maryse et al

in Journal of Applied Entomology (2014), 138(5), 338-345

The multicoloured Asian ladybeetle, Harmonia axyridis (Pallas), aggregates inside dwellings during winters to survive the cold. This beetle uses chemical cues coming from congeners to select an ... [more ▼]

The multicoloured Asian ladybeetle, Harmonia axyridis (Pallas), aggregates inside dwellings during winters to survive the cold. This beetle uses chemical cues coming from congeners to select an overwintering site. Recent research has shown that they preferentially gather at places where conspecifics previously laid a substrate marking made up of saturated and unsaturated hydrocarbons. Some authors have reported that H. axyridis colonizes the same overwintering sites from 1 year to another. Herein, the hypothesis that this substrate marking is used by H. axyridis to settle in the same aggregation sites from one winter to another was tested. To this aim, the temporal modification in the chemical profile of the hydrocarbon marking was studied by performing chromatographic analyses. After 1 year, the overall profile was modified qualitatively and quantitatively: the unsaturated hydrocarbons were no longer detected while some saturated hydrocarbons were still present in large quantities. In a behavioural assay conducted in the laboratory, the 12-month-old marking did not induce the aggregation of H. axyridis. This result indicates that the chemical markings left by conspecifics during a previous aggregation period in an overwintering site are not sufficient to induce the gathering of the newly arriving individuals. [less ▲]

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See detailMédecin de famille dans le premier monde
Jamoulle, Marc ULg

in Santé Conjuguée (2014), 68

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See detailA New Three Object Triangulation Algorithm for Mobile Robot Positioning
Pierlot, Vincent ULg; Van Droogenbroeck, Marc ULg

in IEEE Transactions on Robotics (2014), 30(3), 566-577

Positioning is a fundamental issue in mobile robot applications. It can be achieved in many ways. Among them, triangulation based on angles measured with the help of beacons is a proven technique. Most of ... [more ▼]

Positioning is a fundamental issue in mobile robot applications. It can be achieved in many ways. Among them, triangulation based on angles measured with the help of beacons is a proven technique. Most of the many triangulation algorithms proposed so far have major limitations. For example, some of them need a particular beacon ordering, have blind spots, or only work within the triangle defined by the three beacons. More reliable methods exist; however, they have an increasing complexity or they require to handle certain spatial arrangements separately. In this paper, we present a simple and new three object triangulation algorithm, named ToTal, that natively works in the whole plane, and for any beacon ordering. We also provide a comprehensive comparison between many algorithms, and show that our algorithm is faster and simpler than comparable algorithms. In addition to its inherent efficiency, our algorithm provides a very useful and unique reliability measure, assessable anywhere in the plane, which can be used to identify pathological cases, or as a validation gate in Kalman filters. [less ▲]

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See detailVolitional electromyographic responses in disorders of consciousness
Habbal, Dina; Gosseries, Olivia ULg; Noirhomme, Quentin ULg et al

in Brain Injury (2014)

The aim of the study was to validate the use of electromyography (EMG) for detecting responses to command in patients in vegetative state/unresponsive wakefulness syndrome (VS/UWS) or in minimally ... [more ▼]

The aim of the study was to validate the use of electromyography (EMG) for detecting responses to command in patients in vegetative state/unresponsive wakefulness syndrome (VS/UWS) or in minimally conscious state (MCS). Methods: Thirty-eight patients were included in the study (23 traumatic, 25 patients >1 year post-onset), 10 diagnosed as being in VS/UWS, eight in MCS- (no response to command) and 20 in MCS+ (response to command). Eighteen age-matched controls participated in the experiment. The paradigm consisted of three commands (i.e. 'Move your hands', 'Move your legs' and 'Clench your teeth') and one control sentence (i.e. 'It is a sunny day') presented in random order. Each auditory stimulus was repeated 4-times within one block with a stimulus-onset asynchrony of 30 seconds. Results: Post-hoc analyses with Bonferroni correction revealed that EMG activity was higher solely for the target command in one patient in permanent VS/UWS and in three patients in MCS+. Conclusion: The use of EMG could help clinicians to detect conscious patients who do not show any volitional response during standard behavioural assessments. However, further investigations should determine the sensitivity of EMG as compared to neuroimaging and electrophysiological assessments. [less ▲]

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See detailAltération de la fonction rénale chez le patient âgé, comment gérer?
KRZESINSKI, Jean-Marie ULg; DELANAYE, Pierre ULg

in Revue Médicale de Liège (2014), 69(5-6), 287-293

From age 30 onwards, kidney function physiologically decreases although this deterioration cannot yet be called chronic kidney disease. The latter appears in those exposed to cardiovascular risk factors ... [more ▼]

From age 30 onwards, kidney function physiologically decreases although this deterioration cannot yet be called chronic kidney disease. The latter appears in those exposed to cardiovascular risk factors associated with inflammation and oxidative stress. A diffuse atherosclerosis then develops Patients with a decreased glomerular filtration rate, especially below the threshold of 45 ml/min, are characterised by a poor physical heath and by cognitive disorders, leading to frailty. In these conditions, a management strategy to reduce the increased risk of acute kidney injury should be outlined and the need for renal replacement therapy be considered. One must try to maintain the best possible quality of life, promoting in some situations a conservative approach. [less ▲]

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See detailEcologie, diversité spécifique et abondance des petits mammifères de la ville de Cotonou au Bénin (Afrique de l’Ouest)
Houèmènou, Gualbert; Kassa, B.; Libois, Roland ULg

in International Journal of Biological and Chemical Sciences (2014), 8(3), 1202-1213

L’étude de la diversité des petits mammifères de la ville de Cotonou (Bénin) selon les types de milieux (habités ou non) a été réalisée du 25 août 2004 au 25 mai 2005 avec interruptions. Les campagnes de ... [more ▼]

L’étude de la diversité des petits mammifères de la ville de Cotonou (Bénin) selon les types de milieux (habités ou non) a été réalisée du 25 août 2004 au 25 mai 2005 avec interruptions. Les campagnes de captures ont été effectuées. Au total, 348 petits mammifères ont été capturés pour un effort de piégeage de 2652 nuits-pièges et 11 espèces comprenant 3 espèces (Rattus rattus, Rattus norvegicus et Mus domesticus) cosmopolites représentant 25% du total et les espèces africaines (Crocidura olivieri, Crocidura sp., Arvicanthis niloticus,Cricetomys gambianus, Dasymys rufulus, Mastomys sp., Gerbilliscus kempi, Taterillus gracilis) représentant 75% du total, ont été inventoriées. La prépondérance de Rattus rattus dans les captures avec 59,8% de Mastomys sp. (13,5%) et de C. olivieri (8,6%) a été notée. Mus domesticus (0,29%), Arvicanthis niloticus (0,86%) et Crocidura sp. (0,86%) sont faiblement représentées. L’indice de diversité de Shannon est de 2,08 dans la ville de Cotonou, de 2,70 dans les milieux non habités et de 1,45 dans les milieux habités où l’on ne trouve quasiment que les rats et souris. Le domaine de l’aéroport (aéroport international de Cotonou) et quelques zones marécageuses, inaccessibles à la population, constituent des zones refuges où l’indice de diversité des petits mammifères est relativement élevé. [less ▲]

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See detailSynthèse bibliographique : l'écologie larvaire des culicoïdes (Diptera : Ceratopogonidae)
Zimmer, Jean-Yves ULg; Haubruge, Eric ULg; Francis, Frédéric ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2014), 18(2), 301-312

Cet article présente une synthèse de l’écologie larvaire des culicoïdes (Diptera : Ceratopogonidae) en vue de rassembler les connaissances, souvent très parsemées, des sites d’oviposition et des habitats ... [more ▼]

Cet article présente une synthèse de l’écologie larvaire des culicoïdes (Diptera : Ceratopogonidae) en vue de rassembler les connaissances, souvent très parsemées, des sites d’oviposition et des habitats larvaires actuellement identifiés à travers le monde pour les principales espèces de culicoïdes. Ces moucherons piqueurs hématophages sont impliqués dans la transmission de divers parasites (protozoaires et filaires) et virus aux animaux. Le développement larvaire des culicoïdes est généralement optimal dans les substrats humides et riches en débris organiques divers. Cependant, chaque espèce présente ses propres exigences écologiques et se trouve par conséquent dans des micro-habitats spécifiques. Dans cette synthèse, les gites larvaires sont répartis en substrats aquatiques et semi-aquatiques d’eau douce et d’eau salée ou saumâtre, substrats terrestres et substrats anthropiques liés à l’élevage. Les gites larvaires de nombreuses espèces appartenant au genre Culicoides Latreille demeurent cependant encore méconnus. La connaissance de ces derniers et leur caractérisation sont pourtant essentielles pour permettre la mise au point de stratégies de lutte efficaces contre ces insectes vecteurs, permettant ainsi de renforcer la vaccination du bétail et les autres moyens de lutte mis en oeuvre. Les habitats larvaires actuellement identifiés pourraient permettre d’orienter les investigations des recherches écologiques futures et les propositions de contrôle de ces moucherons vecteurs. [less ▲]

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See detailLe portrait photographique d'écrivain vu de face et de profil
Bertrand, Jean-Pierre ULg; Durand, Pascal ULg; Lavaud, Martine

in COnTEXTES : Revue de Sociologie de la Littérature (2014), 14

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See detailEfficiency of haplotype-based methods to fine-map QTLs and embryonic lethal variants affecting fertility: Illustration with a deletion segregating in Nordic Red cattle
Kadri, Naveen Kumar ULg; Sahana, Goutam; Guldbrandtsen, Bernt et al

in Livestock Science (2014), 166

Despite its importance, fertility has been declining in many cattle populations. In dairy cattle, this decline is often attributed to the negative correlation between fertility and productions traits ... [more ▼]

Despite its importance, fertility has been declining in many cattle populations. In dairy cattle, this decline is often attributed to the negative correlation between fertility and productions traits. Recent studies showed that embryonic lethal variants might also account for a non-negligible fraction of the fertility decline. Therefore identification of such embryonic lethal variants is essential to improve fertility. We herein illustrate, with an example of a large recessive lethal deletion recently identified in Nordic Red cattle, that haplotype-based method are particularly efficient to identify such embryonic lethal variants. We first show that haplotypes can be used in traditional QTL mapping approaches and that they present very high linkage disequilibrium with underlying variants. Haplotypes can also be used in scan for lack of homozygosity. Indeed,if a haplotype is associated to a recessive lethal variant, significantly fewer living individuals will be homozygote for that haplotype than expected. For both approaches, haplotype- based methods were particularly efficient. The lack of homozygosity approach achieved higher significance than the QTL approach. Only frequent variants can be detected with both approaches unless huge genotyped cohorts are available. An alternative approach would rely on identifying potential harmful variants in next-generation sequencing data followed by the genotyping of a larger population for these variants. [less ▲]

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See detailIdentifying endophenotypes of autism: a multivariate approach
Segovia-Román, Fermín ULg; Holt, Rosemary; Spencer, Michael et al

in Frontiers in Computational Neuroscience (2014), 8

The existence of an endophenotype of autism spectrum condition (ASC) has been recently suggested by several commentators. It can be estimated by finding differences between controls and people with ASC ... [more ▼]

The existence of an endophenotype of autism spectrum condition (ASC) has been recently suggested by several commentators. It can be estimated by finding differences between controls and people with ASC that are also present when comparing controls and the unaffected siblings of ASC individuals. In this work, we used a multivariate methodology applied on magnetic resonance images to look for such differences. The proposed procedure consists of combining a searchlight approach and a support vector machine classifier to identify the differences between three groups of participants in pairwise comparisons: controls, people with ASC and their unaffected siblings. Then we compared those differences selecting spatially collocated as candidate endophenotypes of ASC. [less ▲]

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See detailBeAMS: a Beacon based Angle Measurement Sensor for mobile robot positioning
Pierlot, Vincent ULg; Van Droogenbroeck, Marc ULg

in IEEE Transactions on Robotics (2014), 30(30), 533-549

Positioning is a fundamental issue in mobile robot applications, and it can be achieved in multiple ways. Among these methods, triangulation based on angle measurements is widely used, robust, accurate ... [more ▼]

Positioning is a fundamental issue in mobile robot applications, and it can be achieved in multiple ways. Among these methods, triangulation based on angle measurements is widely used, robust, accurate, and flexible. This paper presents BeAMS, a new active beacon-based angle measurement system used for mobile robot positioning. BeAMS introduces several major innovations. One innovation is the use of a unique unsynchronized channel with On-Off Keying modulated infrared signals to measure angles and to identify the beacons. We also introduce a new mechanism to measure angles: our system detects a beacon when it enters and leaves an angular window. We show that the estimator resulting from the center of this angular window provides an unbiased estimate of the beacon angle. A theoretical framework for a thorough performance analysis of BeAMS is provided. We establish the upper bound of the variance and validate this bound through experiments and simulations; the overall error measure of BeAMS is lower than 0.24 deg for an acquisition rate of 10 Hz. In conclusion, BeAMS is a low power, flexible, and robust solution for angle measurement, and a reliable component for robot positioning. [less ▲]

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See detailCAMKKβ/AMPK-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets
Onselaer, Marie-Blanche; Oury, Cécile ULg; Hunter, Roger W et al

in Journal of Thrombosis and Haemostasis [=JTH] (2014), 12(6), 973-986

Background. Platelet activation requires sweeping morphological changes, supported by contraction and remodelling of platelet actin cytoskeleton. In various other cell types, AMP-activated protein kinase ... [more ▼]

Background. Platelet activation requires sweeping morphological changes, supported by contraction and remodelling of platelet actin cytoskeleton. In various other cell types, AMP-activated protein kinase (AMPK) controls the phosphorylation state of cytoskeletal targets. Objective. We hypothesized that AMPK is activated during platelet aggregation and contributes to the control of cytoskeletal targets. Results. We found that AMPK-α1 was mainly activated by thrombin and not by other platelet agonists in purified human platelets. Thrombin activated AMPK-α1 ex vivo via a Ca2+/calmodulin-dependent kinase kinase β (CAMKKβ)-dependent pathway. Pharmacological inhibition of CAMKKβ blocked thrombin-induced platelet aggregation and counteracted thrombin-induced phosphorylation of several cytoskeletal proteins, namely, regulatory myosin light chains (MLC), cofilin and vasodilator-stimulated phosphoprotein (VASP), three key elements involved in actin cytoskeleton contraction and polymerization. Platelets isolated from mice lacking AMPK-α1 exhibited reduced aggregation in response to thrombin, associated with a defect in MLC, cofilin and VASP phosphorylation and actin polymerization. More importantly, we show for the first time that AMPK pathway was activated in platelets of patients undergoing major cardiac surgery, in a heparin-sensitive manner. Conclusion. AMPK-α1 is activated by thrombin in human platelets. It controls phosphorylation of key cytoskeletal targets and actin cytoskeleton remodelling during platelet aggregation. [less ▲]

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See detailDe Nadar à Dornac. Hexis corporelle et figuration photographique de l'écrivain
Durand, Pascal ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2014), 14

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See detailComplex dynamics of a nonlinear aerospace structure: experimental identification and modal interactions
Noël, Jean-Philippe ULg; Renson, Ludovic ULg; Kerschen, Gaëtan ULg

in Journal of Sound & Vibration (2014), 333

Nonlinear system identification is a challenging task in view of the complexity and wide variety of nonlinear phenomena. The present paper addresses the identification of a real-life aerospace structure ... [more ▼]

Nonlinear system identification is a challenging task in view of the complexity and wide variety of nonlinear phenomena. The present paper addresses the identification of a real-life aerospace structure possessing a strongly nonlinear component with multiple mechanical stops. The complete identification procedure, from nonlinearity detection and characterization to parameter estimation, is carried out based upon experimental data. The combined use of various analysis techniques, such as the wavelet transform and the restoring force surface method, brings different perspectives to the dynamics. Specifically, the structure is shown to exhibit particularly interesting nonlinear behaviors, including jumps, modal interactions, force relaxation and chattering during impacts on the mechanical stops. [less ▲]

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See detailDe Europese Unie en Brazilië: eindelijk een (strategisch?) partnershap
Santander, Sébastian ULg

in Internationale Spectator (2014), 68(6), 40-44

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See detailGember: hoogwaardige anti-emeticum in de officinale praktijk
Angenot, Luc ULg

in Farma Sfeer (2014), 18(195), 30-31

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See detailPrediction of SOx and NOx Emissions from a Medium Size Biomass Boiler Biomass and Bioenergy
Sartor, Kevin ULg; Restivo, Yannick ULg; Ngendakumana, Philippe ULg et al

in Biomass and Bioenergy (2014), 65

While small and medium size biomass combined heat and power (CHP) plants (i.e., up to 5 MW of electrical rated power) represent an attractive option to exploit locally available biomass resources at low ... [more ▼]

While small and medium size biomass combined heat and power (CHP) plants (i.e., up to 5 MW of electrical rated power) represent an attractive option to exploit locally available biomass resources at low cost, the corresponding investment per unit of rated power significantly rises when the installed power decreases. In these cases, secondary pollutant emissions control measures are most of the time not economically viable and primary emissions control must be used alone to avoid the formation of undesired compounds such as $NO_x$ and $SO_x$. Primary control measures require the careful optimization of fuel quality and combustion process. For plant operators, being able to accommodate biomass quality changes in order to minimize the fuel cost can be of great importance in order to guarantee the profitability of the plant. This contribution is dedicated to the development of a zero-dimensional (input-output) combustion simulation model able to predict the pollutants emissions resulting from complete and incomplete combustion with respect to varying combustion operation (ambient temperature, humidity, fumes recirculation,..). This tool is intended to be integrated in a global simulation model of the CHP plant and the attached district heating network installed on the University campus in Liège. Doing so, the plant operation can be optimized with respect to economic as well as environmental and energetic aspects (3E approach) thus ensuring the sustainability of the approach. [less ▲]

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See detailEstimation of inbreeding rates and extinction risk of forty one Belgian chicken breeds in 2005 and 2010
Moula, Nassim ULg; Philippe, François-Xavier ULg; Antoine-Moussiaux, Nicolas ULg et al

in Archivos de zootecnia (2014), 63(2),

In Belgium, as generally in Europe, the dominant position of the high producing commercial strains specialized in meat or eggs production threats of extinction the local traditional breeds. In this work ... [more ▼]

In Belgium, as generally in Europe, the dominant position of the high producing commercial strains specialized in meat or eggs production threats of extinction the local traditional breeds. In this work, a follow up of the changes in populations size, and the rates of inbreeding of the Belgian poultry breeds, has been carried out in 2005 and 2010. About forty breeds were concerned. The Belgian hen breeds being overwhelmingly under threat of extinction, because of the low number of individuals by breed. For each of these breeds, various criteria were considered, risk status, breeding male to breeding female ratio, effective population size, effective population size to actual size ratio and rate of inbreeding. [less ▲]

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See detailFire salamander (Salamandra salamandra) in Larzac plateau: low occurrence, pond-breeding and cohabitation of larvae with paedomorphic palmate newts (Lissotriton helveticus)
Denoël, Mathieu ULg; Winandy, Laurane ULg

in Acta herpetologica (2014), 9(1), 43-49

Alternative reproductive strategies are widespread in caudate amphibians. Among them, fire salamanders (Salamandra salamandra) usually rely on streams to give birth to aquatic larvae but also use ponds ... [more ▼]

Alternative reproductive strategies are widespread in caudate amphibians. Among them, fire salamanders (Salamandra salamandra) usually rely on streams to give birth to aquatic larvae but also use ponds, whereas palmate newt larvae (Lissotriton helveticus) typically metamorphose into terrestrial juveniles, but can also reproduce in retaining their gills, a process known as paedomorphosis. Here we report repeated observations of an unusual case of coexistence of these two alternative traits in the same pond (Larzac, France). The prevalence of fire salamanders in Southern Larzac was very low (pond occupancy: 0.36%). The observed abundance of fire salamander larvae and paedomorphic newts was also low in the studied pond. On one hand, the rarity of this coexistence pattern may suggest that habitat characteristics may not be optimal or that competition or predation processes might be operating. However, these hypotheses remain to be tested. On the other hand, as this is the only known case of breeding in Southern Larzac, it could be considered to be at a high risk of extirpation. [less ▲]

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See detailPrise en charge de l'hypertension artérielle du patient âgé
XHIGNESSE, Patricia ULg; Saint-Remy, Annie ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2014), 69(5-6), 294-300

High blood pressure is very frequent in the elderly; it represents a real threat for the patient’s health and a source of huge costs for the economic system. Systolic hypertension is the most frequent ... [more ▼]

High blood pressure is very frequent in the elderly; it represents a real threat for the patient’s health and a source of huge costs for the economic system. Systolic hypertension is the most frequent form observed in the old, due to large arteries stiffness. Antihypertensive therapy has proven effective to decrease significantly the cardiovascular morbi-mortality and total mortality in this population. A non pharmacological approach is also very useful, but should not be too restrictive. Blood pressure target in patients older than 65 (and, particularly, in octogenarians) is 150/80 mmHg. Blood pressure should be checked in the upright position before changing the drug dosage. The first line therapy in the old should generally be a calcium channel antagonist or a low dose diuretic. [less ▲]

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See detailNetworks for improving care in patients with acute coronary syndrome: A framework.
Radke, Peter W.; Halvorsen, Sigrun; Jukema, J. Wouter et al

in Acute cardiac care (2014), 16(2), 41-8

In recent years, it has become evident that the level of guideline adherence in patients presenting with acute coronary syndrome (ACS) is highly correlated with patient outcomes. Unfortunately, guideline ... [more ▼]

In recent years, it has become evident that the level of guideline adherence in patients presenting with acute coronary syndrome (ACS) is highly correlated with patient outcomes. Unfortunately, guideline adherence is low in some geographic areas and especially in those patients at high-risk. Regional networks including ambulance systems and hospitals with catheterization laboratories are able to increase guideline adherence and patient outcomes by streamlining the critical pre- and intra-hospital processes as well as improving timely access to invasive procedures and recommended medication. Successful organization of an ACS network requires engagement of multiple stakeholders to create effective solutions for the specific local setting. There is no 'one-size-fits all' strategy to set-up and successfully run an ACS network. We present a framework for how to set up and organize an effective ACS network, delivering guideline-based care to improve patient outcomes. [less ▲]

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See detailEffect of concentration in Ge-Te liquids: A combined density functional and neutron scattering study
Micoulaut, Matthieu; Coulet, M.V.; Piarristeguy, A. et al

in Physical Review. B : Solid State (2014), 89(17), 174205

The structural properties of three compositions of Ge-Te liquids (Ge10Te90, Ge15Te85, Ge20Te80) are studied from a combination of density functional based molecular dynamics simulations and neutron ... [more ▼]

The structural properties of three compositions of Ge-Te liquids (Ge10Te90, Ge15Te85, Ge20Te80) are studied from a combination of density functional based molecular dynamics simulations and neutron scattering experiments. We investigate structural properties including structure factors, pair distribution functions, angular distributions, coordination numbers, neighbor distributions and compare our results with experimental findings. Most noticeable is the good agreement found in the reproduction of the structure in real and reciprocal space, resulting from the incorporation of dispersion forces in the simulation. This leads to Ge and Te coordination numbers which are lower than in previous studies and which can now be followed with temperature, while also strongly depending on the chosen cutoff distance. Results show a gradual conversion of higher coordinated species (TeIV, GeV) into lower coordinated ones at lower temperature, while leaving anticipated coordinations from the octet rule (TeII and GeIV) nearly unchanged. Structural correlations are characterized as a function of temperature and composition. The vibrational density of states is also measured from inelastic neutron scattering for different compositions and temperatures, and compared to the simulated counterpart which exhibits a reasonable agreement at low frequency. [less ▲]

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See detailFalsos positivos de C5-carnitina elevada en cribado neonatal: A que son debidos?
Yahyaoui, Raquel; Rueda; Dayaldasani, Anita et al

in Medicina Clinica (2014)

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See detailGenome-Wide Association Interaction Analysis for Alzheimer’s Disease
Gusareva, Elena ULg; Carrasquillo, Minerva M.; Bellenguez, Céline et al

in Neurobiology of Aging (2014)

We propose a minimal protocol for exhaustive genome-wide association interaction analysis that involves screening for epistasis over large-scale genomic data combining strengths of different methods and ... [more ▼]

We propose a minimal protocol for exhaustive genome-wide association interaction analysis that involves screening for epistasis over large-scale genomic data combining strengths of different methods and statistical tools. The different steps of this protocol are illustrated on a real-life data application for Alzheimer's disease (AD) (2259 patients and 6017 controls from France). Particularly, in the exhaustive genome-wide epistasis screening we identified AD-associated interacting SNPs-pair from chromosome 6q11.1 (rs6455128, the KHDRBS2 gene) and 13q12.11 (rs7989332, the CRYL1 gene) (p = 0.006, corrected for multiple testing). A replication analysis in the independent AD cohort from Germany (555 patients and 824 controls) confirmed the discovered epistasis signal (p = 0.036). This signal was also supported by a meta-analysis approach in 5 independent AD cohorts that was applied in the context of epistasis for the first time. Transcriptome analysis revealed negative correlation between expression levels of KHDRBS2 and CRYL1 in both the temporal cortex (β = -0.19, p = 0.0006) and cerebellum (β = -0.23, p < 0.0001) brain regions. This is the first time a replicable epistasis associated with AD was identified using a hypothesis free screening approach. [less ▲]

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See detailNear-death experiences in non-life-threatening events and coma of different etiologies.
Charland-Verville, Vanessa ULg; Jourdan, Jean-Pierre; Thonnard, Marie ULg et al

in Frontiers in human neuroscience (2014), 8(203),

BACKGROUND: Near death experiences (NDEs) are increasingly being reported as a clearly identifiable physiological and psychological reality of clinical significance. However, the definition and causes of ... [more ▼]

BACKGROUND: Near death experiences (NDEs) are increasingly being reported as a clearly identifiable physiological and psychological reality of clinical significance. However, the definition and causes of the phenomenon as well as the identification of NDE experiencers is still a matter of debate. To date, the most widely used standardized tool to identify and characterize NDEs in research is the Greyson NDE scale. Using this scale, retrospective and prospective studies have been trying to estimate their incidence in various populations but few studies have attempted to associate the experiences' intensity and content to etiology. METHODS: This retrospective investigation assessed the intensity and the most frequently recounted features of self-reported NDEs after a non-life-threatening event (i.e., "NDE-like" experience) or after a pathological coma (i.e., "real NDE") and according to the etiology of the acute brain insult. We also compared our retrospectively acquired data in anoxic coma with historical data from the published literature on prospective post-anoxic studies using the Greyson NDE scale. RESULTS: From our 190 reports who met the criteria for NDE (i.e., Greyson NDE scale total score >7/32), intensity (i.e., Greyson NDE scale total score) and content (i.e., Greyson NDE scale features) did not differ between "NDE-like" (n = 50) and "real NDE" (n = 140) groups, nor within the "real NDE" group depending on the cause of coma (anoxic/traumatic/other). The most frequently reported feature was peacefulness (89-93%). Only 2 patients (1%) recounted a negative experience. The overall NDE core features' frequencies were higher in our retrospective anoxic cohort when compared to historical published prospective data. CONCLUSIONS: It appears that "real NDEs" after coma of different etiologies are similar to "NDE-like" experiences occurring after non-life threatening events. Subjects reporting NDEs retrospectively tend to have experienced a different content compared to the prospective experiencers. [less ▲]

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See detailProbabilistic Assessment of the Lifetime of Low-Earth-Orbit Spacecraft: Uncertainty Characterization
Dell'Elce, Lamberto ULg; Arnst, Maarten ULg; Kerschen, Gaëtan ULg

in Journal of Guidance Control & Dynamics (2014)

Orbital lifetime estimation is a problem of great timeliness and importance in astrodynamics. In view of the stochastic nature of the thermosphere and of the complexity of drag modeling, any deterministic ... [more ▼]

Orbital lifetime estimation is a problem of great timeliness and importance in astrodynamics. In view of the stochastic nature of the thermosphere and of the complexity of drag modeling, any deterministic assessment of orbital lifetime is likely to be bound to failure. This is why the present paper performs uncertainty quantification of satellite orbital lifetime estimation. Specifically, this paper focuses on the probabilistic characterization of the dominant sources of uncertainty inherent to low-altitude satellites. Uncertainties in the initial state of the satellite and in the atmospheric drag force, as well as uncertainties introduced by modeling limitations associated with atmospheric density models, are considered. Mathematical statistics methods, in conjunction with mechanical modeling considerations, are used to infer the probabilistic characterization of these uncertainties from experimental data and atmospheric density models. This characterization step facilitates the application of uncertainty propagation and sensitivity analysis methods, which in turn allows gaining insight into the impact that these uncertainties have on the orbital lifetime. The proposed developments are illustrated using one CubeSat of the QB50 constellation. [less ▲]

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See detailTemperature regimes and aphid density interactions differentially influence VOC emissions in Arabidopsis
Hien, Truong Thi Dieu ULg; Delory, Benjamin ULg; Vanderplanck, Maryse et al

in Arthropod-Plant Interactions (2014), 8(4), 317-327

The effects of volatile emissions from plants exposed to individual abiotic and biotic stresses are well documented. However, the influence of multiple stresses on plant photosynthesis and defense ... [more ▼]

The effects of volatile emissions from plants exposed to individual abiotic and biotic stresses are well documented. However, the influence of multiple stresses on plant photosynthesis and defense responses, resulting in a variety of volatile profiles has received little attention. In this study, we investigated how temperature regimes in the presence and absence of the sucking insect Myzus persicae affected volatile organic compound emissions in Arabidopsis over three time periods (0-24 h, 24-48 h, and 48-72 h). Headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry was used to evaluate Arabidopsis volatile organic compounds. The results showed that under laboratory conditions, eight volatile classes [alcohols (mainly 2-ethyl-hexan-1-ol), ketone (6-methyl hept-5-en-2-one), esters (mainly (Z)-3-hexenyl acetate), aldehydes (mainly phenylacetaldehyde), isothiocyanates (mainly 4-methylpentyl isothiocyanate), terpenes (mainly (E,E)-α-farnesene), nitrile (5-(methylthio) pentanenitrile), and sulfide (dimethyl trisulfide)] were observed on plants exposed to stress combinations, whereas emissions of six volatile classes were observed during temperature stress treatments alone (with the exception of nitriles and sulfides). Aphid density at high temperature combinations resulted in significantly higher isothiocyanate, ester, nitrile and sulfide proportions. The results of the present study provide an insight into the effects of temperature - aphid interactions on plant volatile emissions. [less ▲]

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See detailInteractive comment on “Improved routines to model the ocean carbonate system: mocsy 1.0” by J. C. Orr and J.-M Epitalon
Munhoven, Guy ULg

in Geoscientific Model Development Discussions [=GMDD] (2014), 7

The manuscript "Improved routines to model the ocean carbonate system: mocsy 1.0" by J. C. Orr and J.-M Epitalon is reviewed and related issues and ideas are discussed.

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See detailAn independent SSVEP-based brain-computer interface in locked-in-syndrome
Lesenfants, Damien ULg; Habbal, Dina; Lugo et al

in Journal of Neural Engineering (2014)

OBJECTIVE: Steady-state visually evoked potential (SSVEP)-based brain-computer interfaces (BCIs) allow healthy subjects to communicate. However, their dependence on gaze control prevents their use with ... [more ▼]

OBJECTIVE: Steady-state visually evoked potential (SSVEP)-based brain-computer interfaces (BCIs) allow healthy subjects to communicate. However, their dependence on gaze control prevents their use with severely disabled patients. Gaze-independent SSVEP-BCIs have been designed but have shown a drop in accuracy and have not been tested in brain-injured patients. In the present paper, we propose a novel independent SSVEP-BCI based on covert attention with an improved classification rate. We study the influence of feature extraction algorithms and the number of harmonics. Finally, we test online communication on healthy volunteers and patients with locked-in syndrome (LIS). APPROACH: Twenty-four healthy subjects and six LIS patients participated in this study. An independent covert two-class SSVEP paradigm was used with a newly developed portable light emitting diode-based 'interlaced squares' stimulation pattern. MAIN RESULTS: Mean offline and online accuracies on healthy subjects were respectively 85 ± 2% and 74 ± 13%, with eight out of twelve subjects succeeding to communicate efficiently with 80 ± 9% accuracy. Two out of six LIS patients reached an offline accuracy above the chance level, illustrating a response to a command. One out of four LIS patients could communicate online. SIGNIFICANCE: We have demonstrated the feasibility of online communication with a covert SSVEP paradigm that is truly independent of all neuromuscular functions. The potential clinical use of the presented BCI system as a diagnostic (i.e., detecting command-following) and communication tool for severely brain-injured patients will need to be further explored. [less ▲]

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See detailMeandering jets in shallow rectangular reservoirs: POD analysis and identification of coherent structures
Peltier, Yann ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Experiments in Fluids (2014), 55

The effect of the shallowness on meandering jets in a shallow rectangular reservoir is investigated. Four meandering flows were investigated in an experimental shallow rectangular reservoir. Their ... [more ▼]

The effect of the shallowness on meandering jets in a shallow rectangular reservoir is investigated. Four meandering flows were investigated in an experimental shallow rectangular reservoir. Their boundary conditions were chosen to cover a large range of friction numbers (defined with the sudden expansion width). Due to the unsteady characteristics of the flows, a Proper Orthogonal Decomposition of the fluctu-ating part of the surface velocity fields measured using LSPIV was used for discriminating the flow struc-tures responsible for the meandering of the jet. Less than 1 % of the calculated POD modes significantly contribute to the meandering of the jet and two types of instability are in competition in such a flow con-figuration. The sinuous mode is the dominant mode in the flow and it induces the meandering of the flow, while the varicose mode is a source of local mixing and weakly participates to the flow. The fluctuating velocity fields were then reconstructed using the POD modes corresponding to 80% of the total mean fluctuating kinetic energy and the coherent structures were identified using the residual vorticity, their centres being localised using a topology algorithm. The trajectories of the structures centres emphasize that at high friction number the coherent structures are small and laterally paired in the near, middle and far fields of the jet, while with decreasing friction number the structures merge into large horizontal vortices in the far-field of the jet, their trajectories showing more variability in space and time. The analysis of the stability regime finally reveals that the sinuous mode is convectively unstable and may become absolutely unstable at the end of the reservoir when the friction number is small. [less ▲]

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