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See detailFeasibility of improving a priori regional climate model estimates of Greenland ice sheet surface mass loss through assimilation of measured ice surface temperatures
Navari, M.; Margulis, S.A.; Bateni, S.M. et al

in Cryosphere (The) (2016), 10

The Greenland ice sheet (GrIS) has been the focus of climate studies due to its considerable impact on sea level rise. Accurate estimates of surface mass fluxes would contribute to understanding the cause ... [more ▼]

The Greenland ice sheet (GrIS) has been the focus of climate studies due to its considerable impact on sea level rise. Accurate estimates of surface mass fluxes would contribute to understanding the cause of its recent changes and would help to better estimate the past, current and future contribution of the GrIS to sea level rise. Though the estimates of the GrIS surface mass fluxes have improved significantly over the last decade, there is still considerable disparity between the results from different methodologies (e.g., Rae et al., 2012; Vernon et al., 2013). The data assimilation approach can merge information from different methodologies in a consistent way to improve the GrIS surface mass fluxes. In this study, an ensemble batch smoother data assimilation approach was developed to assess the feasibility of generating a reanalysis estimate of the GrIS surface mass fluxes via integrating remotely sensed ice surface temperature measurements with a regional climate model (a priori) estimate. The performance of the proposed methodology for generating an improved posterior estimate was investigated within an observing system simulation experiment (OSSE) framework using synthetically generated ice surface temperature measurements. The results showed that assimilation of ice surface temperature time series were able to overcome uncertainties in near-surface meteorological forcing variables that drive the GrIS surface processes. Our findings show that the proposed methodology is able to generate posterior reanalysis estimates of the surface mass fluxes that are in good agreement with the synthetic true estimates. The results also showed that the proposed data assimilation framework improves the root-mean-square error of the posterior estimates of runoff, sublimation/evaporation, surface condensation, and surface mass loss fluxes by 61, 64, 76, and 62 %, respectively, over the nominal a priori climate model estimates. [less ▲]

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See detailAssessment of thermal comfort in existing pre-1945 residential building stock
Singh, M.K.; Attia, Shady ULg; Mahapatra, Sadha et al

in Energy (2016), 98(March), 122-134

The building sector is the third-largest consumer of primary energy in Belgium. This is partly because of the high percentage of old buildings (buildings constructed before 1945) in its building stock ... [more ▼]

The building sector is the third-largest consumer of primary energy in Belgium. This is partly because of the high percentage of old buildings (buildings constructed before 1945) in its building stock. Existing international standards on thermal comfort focus primarily on new construction and commercial buildings but tend to overlook old buildings. This study involves a thermal comfort assessment of fully functional (in use) residential buildings constructed before 1945 in Liège (Belgium). The research methodology is based on continuous long term monitoring of the indoor environment (November 2011 to May 2012) and followed by comfort surveys for selected houses in the city. The analysis of the collected data shows that family composition, envelope performance and the occupants' interaction with the indoor environment greatly affected occupant preferences and functioning of the indoor thermal environment. This study reveals that the occupants' interaction with the indoor thermal environment to restore comfortable thermal conditions varies throughout the day, by adjusting the temperature in different rooms of the house at different times of the day. This study argues that modern comfort standards have failed to estimate the comfort level in these old buildings and, if applied, they would lead to under estimation of their thermal comfort. [less ▲]

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See detailTranscriptome-wide distribution and function of RNA hydroxymethylcytosine
Delatte, Benjamin; Wang, F; Ngoc, LV et al

in Science (2016), 351(6270), 282-285

Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophila. We map the ... [more ▼]

Hydroxymethylcytosine, well described in DNA, occurs also in RNA. Here, we show that hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophila. We map the transcriptome-wide hydroxymethylation landscape, revealing hydroxymethylcytosine in the transcripts of many genes, notably in coding sequences, and identify consensus sites for hydroxymethylation. We found that RNA hydroxymethylation can favor mRNA translation. Tet and hydroxymethylated RNA are found to be most abundant in the Drosophila brain, and Tet-deficient fruitflies suffer impaired brain development, accompanied by decreased RNA hydroxymethylation. This study highlights the distribution, localization, and function of cytosine hydroxymethylation and identifies central roles for this modification in Drosophila. [less ▲]

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See detailColor in the urban environment: A user-oriented protocol for chromatic characterization and the development of a parametric typology
Nguyen, Ngoc Luan ULg; Teller, Jacques ULg

in Color Research and Application (2016)

This article presents a user-oriented protocol that can be used to characterize chromatic attributes of an urban area. A need for both affordable and reliable assessment method of color has been observed ... [more ▼]

This article presents a user-oriented protocol that can be used to characterize chromatic attributes of an urban area. A need for both affordable and reliable assessment method of color has been observed in the field of urban design. The challenge is to provide statistical answers to these two questions: how is color organized, how does it develop its own structure in the city? The main purpose of the research is hence to investigate mean color types within the city via the implementation of a characterization tool; an urban area of the four main classes (historic center, periurban housing districts, working-class neighborhoods, and commercial zones) being characterized by a specific color palette, or a layout of specific color types. The developed instrumentation allows the assessment of the homogeneous and consistent features of an urban district. Their characterization protocol was tested through an application to several streets of the city of Liège (Belgium). [less ▲]

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See detailAssessing the toxicity of Pb- and Sn-based perovskite solar cells in model organism Danio rerio
Babayigit, Aslihan; Dinh Duy Thanh, ULg; Ethirajan, Anitha et al

in Scientific Reports (2016), 6

Intensive development of organometal halide perovskite solar cells has lead to a dramatic surge in power conversion efficiency up to 20%. Unfortunately, the most efficient perovskite solar cells all ... [more ▼]

Intensive development of organometal halide perovskite solar cells has lead to a dramatic surge in power conversion efficiency up to 20%. Unfortunately, the most efficient perovskite solar cells all contain lead (Pb), which is an unsettling flaw that leads to severe environmental concerns and is therefore a stumbling block envisioning their large-scale application. Aiming for the retention of favorable electro-optical properties, tin (Sn) has been considered the most likely substitute. Preliminary studies have however shown that Sn-based perovskites are highly unstable and, moreover, Sn is also enlisted as a harmful chemical, with similar concerns regarding environment and health. To bring more clarity into the appropriateness of both metals in perovskite solar cells, we provide a case study with systematic comparison regarding the environmental impact of Pb- and Sn-based perovskites, using zebrafish (Danio Rerio) as model organism. Uncovering an unexpected route of intoxication in the form of acidification, it is shown that Sn based perovskite may not be the ideal Pb surrogate. [less ▲]

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See detailAnalytical methods used to quantify isoflavones in cow's milk: a review
Daems, Frédéric ULg; Romnee, Jean-Michel; Heuskin, Stéphanie ULg et al

in Dairy Science and Technology (2016)

This paper provides an update and comprehensive review of the analytical methods used for quantifying isoflavones and their metabolites in cow’s milk. Isoflavones are secondary plant metabolites that are ... [more ▼]

This paper provides an update and comprehensive review of the analytical methods used for quantifying isoflavones and their metabolites in cow’s milk. Isoflavones are secondary plant metabolites that are similar to 17 β-estradiol in chemical structure. They form one of the most common categories of phytoestrogens. Numerous health benefits have been attributed to isoflavones, but many of these compounds are also considered to be endocrine disruptors, with adverse effects on health. These contradictory trends offer an attractive prospect for future research, and therefore, sensitive and reliable analytical methods are required to clarify various issues about isoflavones. For this review, a structured methodology was used to select 26 relevant articles published between 2005 and 2015 from the Scopus and CAB Abstract databases. The review discusses individual steps of the analytical procedures described in these articles, including sample preparation, instrumental analysis and validation. The most commonly used analytical procedure is sample preparation involving liquid-liquid extraction and an enzymatic hydrolysis step followed by liquid chromatography with mass spectrometry analysis. Currently, however, there is no standardized procedure for the sample preparation and analysis of isoflavones in milk. [less ▲]

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See detailA comparison of two stretching programs for hamstring muscles: A randomized controlled assessor-blinded study
Demoulin, Christophe ULg; Wolfs, Sébastien ULg; Chevalier, Madeline et al

in Physiotherapy Theory & Practice (2016)

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See detailDPSC colonization of functionalized 3D textiles
Ortiz, Marine; Rosales-Ibáñez, R; Pozos-Guillén, A. et al

in Journal of Biomedical Materials Research, Part B : Applied Biomaterials (2016), 10.1002/jbm.b.33609

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See detailEffects of regional climate change on brown rust disease in winter wheat
JUNK, Jürgen; Kouadio, Louis; Delfosse, Philippe et al

in Climatic Change (2016)

Projected climate changes will affect wheat crop production both in the main processes of plant growth and development but also in the occurrences and severities of plant diseases. We assessed the ... [more ▼]

Projected climate changes will affect wheat crop production both in the main processes of plant growth and development but also in the occurrences and severities of plant diseases. We assessed the potential infection periods of wheat leaf rust (WLR) at two climatologically differentsites in Luxembourg. A threshold-based model, taking hourlyvalues of air temperatures, relative humidity and precipitation during night-time into account, was used for calculating favourable WLR infection days during three periods throughout the cropping season. Field experiments were conducted during the 2003–2013 period at the selected sites. Projected climate data, from a multi model ensemble of regional climate models (spatial resolution 25 km) as well as an additional projection with a higher spatial resolution of 1.3 km, were used for investigating the potential WLR infection periods for two future time spans. Results showed that the infections of WLR were satisfactorily simulated during the development of wheat at both sites for the 2003–2013 period. The probabilities of WLR detection were close to 1 and the critical success index ranged from 0.80 to 0.94 (perfect score = 1 for both). Moreover, the highest proportions of favourable days of WLR infection were simulated during spring and summer at both sites. Regional climate projections showed an increase in temperatures by 1.6 K for 2041–2050 and by 3.7 K for 2091–2100 compared to the reference period1991–2000. Positivetrends infavourableWLR infection conditions occur at both sites more conducive than in the reference period due to projected climatic conditions. [less ▲]

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See detailCollaborative analysis of multi-gigapixel imaging data using Cytomine
Marée, Raphaël ULg; Rollus, Loïc; Stévens, Benjamin et al

in Bioinformatics (2016)

Motivation: Collaborative analysis of massive imaging datasets is essential to enable scientific discoveries. Results: We developed Cytomine to foster active and distributed collaboration of ... [more ▼]

Motivation: Collaborative analysis of massive imaging datasets is essential to enable scientific discoveries. Results: We developed Cytomine to foster active and distributed collaboration of multidisciplinary teams for large-scale image-based studies. It uses web development methodologies and machine learning in order to readily organize, explore, share, and analyze (semantically and quantitatively) multi-gigapixel imaging data over the internet. We illustrate how it has been used in several biomedical applications. Availability: Cytomine (http://www.cytomine.be/) is freely available under an open-source license from http://github.com/cytomine/. A documentation wiki (http://doc.cytomine.be) and a demo server (http://demo.cytomine.be) are also available. [less ▲]

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See detailReview of M.G. Vassanji: Essays on His Works (edited by Asma Sayed)
Munos, Delphine ULg

in South Asian Diaspora (2016), online

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See detailSpin texture induced by oxygen vacancies in strontium perovskite (001) surfaces: A theoretical comparison between SrTiO3 and SrHfO3
Garcia Castro, Andrés Camilo ULg; Vergniory, Maia G.; Bousquet, Eric ULg et al

in Physical Review B (2016), 93

The electronic structure of SrTiO3 and SrHfO3 (001) surfaces with oxygen vacancies is studied by means of first-principles calculations. We reveal how oxygen vacancies within the first atomic layer of the ... [more ▼]

The electronic structure of SrTiO3 and SrHfO3 (001) surfaces with oxygen vacancies is studied by means of first-principles calculations. We reveal how oxygen vacancies within the first atomic layer of the SrTiO3 surface (i) induce a large antiferrodistortive motion of the oxygen octahedra at the surface, (ii) drive localized magnetic moments on the Ti 3d orbitals close to the vacancies, and (iii) form a two-dimensional electron gas localized within the first layers. The analysis of the spin texture of this system exhibits a splitting of the energy bands according to the Zeeman interaction, lowering of the Ti 3dxy level in comparison with dxz and dyz, and also an in-plane precession of the spins. No Rashba-like splitting for the ground state or for the ab initio molecular dynamics trajectory at 400 K is recognized as suggested recently by A. F. Santander-Syro et al. [Nat. Mater. 13, 1085 (2014)]. Instead, a sizable Rashba-like splitting is observed when the Ti atom is replaced by a heavier Hf atom with a much larger spin-orbit interaction. However, we observe the disappearance of the magnetism and the surface two-dimensional electron gas when full structural optimization of the SrHfO3 surface is performed. Our results uncover the sensitive interplay of spin-orbit coupling, atomic relaxations, and magnetism when tuning these Sr-based perovskites. [less ▲]

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See detailBelgique : vers un rééquipement des forces armées
Dumoulin, André ULg

in Revue de Défense nationale (2016)

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See detailFar beyond primary poly(vinylamine)s through free radical copolymerization and amide hydrolysis
Dréan, Mathilde ULg; Guégan, Philippe; Jérôme, Christine ULg et al

in Polymer Chemistry (2016), 7(1), 69-78

Due to their affinity for many supports, their pH responsiveness, metal binding capacity and polyelectro- lyte complexation, poly(vinylamine) derivatives have attracted attention for many applications ... [more ▼]

Due to their affinity for many supports, their pH responsiveness, metal binding capacity and polyelectro- lyte complexation, poly(vinylamine) derivatives have attracted attention for many applications including coatings, water purification, or gas membrane separation. Nevertheless, most of them possess only pendant primary amines despite the possible benefits of incorporating different amino groups along the chain. In this work, a straightforward and scalable synthesis route towards polymers bearing primary and secondary amines, as well as imidazole groups, is reported. The general strategy relies on the radical copolymerization of different vinylamides and vinyl imidazoles followed by the hydrolysis of the resulting poly(vinylamide) derivatives. Binary and ternary free radical copolymerizations of N-vinylacetamide (NVA), N-methyl vinylacetamide (NMVA) and 1-vinylimidazole (VIm) were investigated and the reactivity ratios for each copolymerization system were determined. Thanks to these values a series of statistical copolymers with predictable composition and low deviation over the chain distribution could then be synthesized. Finally, the acidic hydrolysis of the acetamide functions towards the corresponding amine was performed and optimized. Copolymers containing various pendant amino groups and with low dispersity in the chain composition could be obtained, which opens new perspectives for the above mentioned applications. [less ▲]

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See detailProcessing of a new class of multifunctional hybrid for electromagnetic absorption based on a foam filled honeycomb
Bollen, Pierre; Quievy, Nicolas; Detrembleur, Christophe ULg et al

in Materials & Design (2016), 89

A multifunctional hybrid material class in the form of a sandwich panel has been developed towards the com- bined optimization of mechanical and electromagnetic absorption performance. The faces of the ... [more ▼]

A multifunctional hybrid material class in the form of a sandwich panel has been developed towards the com- bined optimization of mechanical and electromagnetic absorption performance. The faces of the panel are made of glass fibre reinforced epoxy composites and the core is made of carbon nanotube reinforced polymer foam filling a metallic honeycomb. The different processing strategies and options tested to fabricate the core material are described aswell as the associated scientific and technological issues. The most efficient processing route is by foaming the nanocomposite with a chemical foaming agent directly inside the honeycomb. This route offers a good surface finish and the operation can be achieved in one step. But, in order to produce large panels with a semi-continuous process, thermo-mechanical insertion of the foamed nanocomposite with supercritical CO2 can be more suitable. The characterization of the electromagnetic absorption of the panels produced by dif- ferent routes shows that the performance is not much sensitive to processing defects making possible upscaling to mass production. [less ▲]

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See detailA prospective cohort study of the clinical presentation of non-traumatic osteonecrosis of the femoral head: spine and knee symptoms as clinical presentation of hip osteonecrosis.
HAUZEUR, Jean-Philippe ULg; Malaise, Michel ULg; de MARTELAER, v

in International Orthopaedics (2016)

To study the clinical presentation of femoral head osteonecrosis (ONFH). Publications dedicated to this aspect of ONFH are rare. Our aim was to systematically collect and describe the clinical data.

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See detailComprehensive comparison of the chemical and structural characterization of landfill leachate and leonardite humic fractions
Tahiri, Abdelghani ULg; Richel, Aurore ULg; Destain, Jacqueline ULg et al

in Analytical and Bioanalytical Chemistry (2016), 408(7), 1917-1928

Humic substances (HS) are complex and heterogeneous mixtures of organic compounds that occur everywhere in the environment. They represent most of the dissolved organic matter in soils, sediments (fossil ... [more ▼]

Humic substances (HS) are complex and heterogeneous mixtures of organic compounds that occur everywhere in the environment. They represent most of the dissolved organic matter in soils, sediments (fossil), water, and landfills. The exact structure of HS macromolecules has not yet been determined because of their complexity and heterogeneity. Various descriptions of HS are used depending on specific environments of origin and research interests. In order to improve the understanding of the structure of HS extracted from landfill leachate (LHS) and commercial HS from leonardite (HHS), this study sought to compare the composition and characterization of the structure of LHS and HHS using elemental composition, chromatographic (high-performance liquid chromatography (HPLC)), and spectroscopic techniques (UV–vis, FTIR, NMR, and MALDI-TOF). The results showed that LHS molecules have a lower molecular weight and less aromatic structure than HHS molecules. The characteristics of functional groups of both LHS and HHS, however, were basically similar, but there was some differences in absorbance intensity. There were also less aliphatic and acidic functional groups and more aromatic and polyphenolic compounds in the humic acid (HA) fraction than in the fulvic acid (FA) and other molecules (OM) fractions of both origins. The differences between LHS and HHS might be due to the time course of humification. Combining the results obtained from these analytical techniques cold improve our understanding of the structure of HS of different origins and thus enhance their potential use. [less ▲]

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See detailVariability in the super-Earth 55 Cnc e
Demory, Brice-Olivier; Gillon, Michaël ULg; Madhusudhan, Nikku et al

in Monthly Notices of the Royal Astronomical Society (2016), 455

Considerable progress has been made in recent years in observations of atmospheric signatures of giant exoplanets, but processes in rocky exoplanets remain largely unknown due to major challenges in ... [more ▼]

Considerable progress has been made in recent years in observations of atmospheric signatures of giant exoplanets, but processes in rocky exoplanets remain largely unknown due to major challenges in observing small planets. Numerous efforts to observe spectra of super-Earths, exoplanets with masses of 1-10 Earth masses, have thus far revealed only featureless spectra. In this paper, we report a 4σ detection of variability in the dayside thermal emission from the transiting super-Earth 55 Cancri e. Dedicated space-based monitoring of the planet in the mid-infrared over eight eclipses revealed the thermal emission from its dayside atmosphere varying by a factor of 3.7 between 2012 and 2013. The amplitude and trend of the variability are not explained by potential influence of star spots or by local thermal or compositional changes in the atmosphere over the short span of the observations. The possibility of large-scale surface activity due to strong tidal interactions possibly similar to Io, or the presence of circumstellar/circumplanetary material appear plausible and motivate future long-term monitoring of the planet. [less ▲]

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See detailInsan her şeyin ölçüsü şüdür? Çağdas dünya ısiğinda Protagoras
Gavray, Marc-Antoine ULg

in Sabah Ülkesi (2016), 46

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See detailCOSMOGRAIL: the COSmological MOnitoring of GRAvItational Lenses. XV. Assessing the achievability and precision of time-delay measurements
Bonvin, V.; Tewes, M.; Courbin, F. et al

in Astronomy and Astrophysics (2016), 585

COSMOGRAIL is a long-term photometric monitoring of gravitationally lensed quasars aimed at implementing Refsdal's time-delay method to measure cosmological parameters, in particular H[SUB]0[/SUB]. Given ... [more ▼]

COSMOGRAIL is a long-term photometric monitoring of gravitationally lensed quasars aimed at implementing Refsdal's time-delay method to measure cosmological parameters, in particular H[SUB]0[/SUB]. Given the long and well sampled light curves of strongly lensed quasars, time-delay measurements require numerical techniques whose quality must be assessed. To this end, and also in view of future monitoring programs or surveys such as the LSST, a blind signal processing competition named Time Delay Challenge 1 (TDC1) was held in 2014. The aim of the present paper, which is based on the simulated light curves from the TDC1, is double. First, we test the performance of the time-delay measurement techniques currently used in COSMOGRAIL. Second, we analyse the quantity and quality of the harvest of time delays obtained from the TDC1 simulations. To achieve these goals, we first discover time delays through a careful inspection of the light curves via a dedicated visual interface. Our measurement algorithms can then be applied to the data in an automated way. We show that our techniques have no significant biases, and yield adequate uncertainty estimates resulting in reduced χ[SUP]2[/SUP] values between 0.5 and 1.0. We provide estimates for the number and precision of time-delay measurements that can be expected from future time-delay monitoring campaigns as a function of the photometric signal-to-noise ratio and of the true time delay. We make our blind measurements on the TDC1 data publicly available. [less ▲]

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See detailANIMA: A data-sharing initiative for neuroimaging meta-analyses
Reid, Andrew T.; Bzdok, Danilo; Genon, Sarah ULg et al

in NeuroImage (2016), 124(B), 1245-1253

Meta-analytic techniques allow cognitive neuroscientists to pool large amounts of data across many individual task-based functional neuroimaging experiments. These methods have been aided by the ... [more ▼]

Meta-analytic techniques allow cognitive neuroscientists to pool large amounts of data across many individual task-based functional neuroimaging experiments. These methods have been aided by the introduction of online databases such as Brainmap.org or Neurosynth.org, which collate peak activation coordinates obtained from thousands of published studies. Findings from meta-analytic studies typically include brain regions which are consistently activated across studies for specific contrasts, investigating cognitive or clinical hypotheses. These regions can be subsequently used as the basis for seed-based connectivity analysis, or formally compared to neuroimaging data in order to help interpret new findings. To facilitate such approaches, we have developed a new online repository of meta-analytic neuroimaging results, named the Archive of Neuroimaging Meta-analyses (ANIMA). The ANIMA platform consists of an intuitive online interface for querying, downloading, and contributing data from published meta-analytic studies. Additionally, to aid the process of organizing, visualizing, and working with these data, we present an open-source desktop application called Volume Viewer. Volume Viewer allows users to easily arrange imaging data into composite stacks, and save these sessions as individual files, which can also be uploaded to the ANIMA database. The application also allows users to perform basic functions, such as computing conjunctions between images, or extracting regions-of-interest or peak coordinates for further analysis. The introduction of this new resource will enhance the ability of researchers to both share their findings and incorporate existing meta-analytic results into their own research. [less ▲]

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See detailAmplitude and frequency variations of oscillation modes in the pulsating DB white dwarf star KIC~08626021. The likely signature of nonlinear resonant mode coupling
Zong, W.; Charpinet, S.; Vauclair, G. et al

in Astronomy and Astrophysics (2016), 585

Context. The signatures of nonlinear effects affecting stellar oscillations are difficult to observe from ground observatories because of the lack of continuous high-precision photometric data spanning ... [more ▼]

Context. The signatures of nonlinear effects affecting stellar oscillations are difficult to observe from ground observatories because of the lack of continuous high-precision photometric data spanning extended enough time baselines. The unprecedented photometric quality and coverage provided by the Kepler spacecraft offers new opportunities to search for these phenomena. Aims: We use the Kepler data accumulated on the pulsating DB white dwarf KIC 08626021 to explore in detail the stability of its oscillation modes, searching, in particular, for evidence of nonlinear behaviors. Methods: We analyze nearly two years of uninterrupted short-cadence data, concentrating on identified triplets that are caused by stellar rotation and that show intriguing behaviors during the course of the observations. Results: We find clear signatures of nonlinear effects that could be attributed to resonant mode coupling mechanisms. These couplings occur between the components of the triplets and can induce different types of behaviors. We first notice that a structure at 3681 μHz, identified as a triplet in previous published studies, is in fact forming a doublet, with the third component being an independent mode. We find that a triplet at 4310 μHz and this doublet at 3681 μHz (most likely the two visible components of an incomplete triplet) have clear periodic frequency and amplitude modulations, which are typical of the so-called intermediate regime of the resonance, with timescales consistent with theoretical expectations. Another triplet at 5073 μHz is likely in a narrow transitory regime in which the amplitudes are modulated while the frequencies are locked. Using nonadiabatic pulsation calculations, based on a model representative of KIC 08626021 to evaluate the linear growth rates of the modes in the triplets, we also provide quantitative information that could be useful for future comparisons with numerical solutions of the amplitude equations. Conclusions: The observed modulations are the clearest hints of nonlinear resonant couplings occurring in white dwarf stars identified so far. These should resonate as a warning to projects that aim at measuring the evolutionary cooling rate of KIC 08626021, and of white dwarf stars in general. Nonlinear modulations of the frequencies can potentially jeopardize any attempt to measure such rates reliably, unless they can be corrected beforehand. These results should motivate further theoretical work to develop the nonlinear stellar pulsation theory. [less ▲]

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See detailThree irradiated and bloated hot Jupiters:. WASP-76b, WASP-82b, and WASP-90b
West, R. G.; Hellier, C.; Almenara, J.-M. et al

in Astronomy and Astrophysics (2016), 585

We report on three new transiting hot Jupiter planets, discovered from the WASP surveys, which we combine with radial velocities from OHP/SOPHIE and Euler/CORALIE and photometry from Euler and TRAPPIST ... [more ▼]

We report on three new transiting hot Jupiter planets, discovered from the WASP surveys, which we combine with radial velocities from OHP/SOPHIE and Euler/CORALIE and photometry from Euler and TRAPPIST. The planets WASP-76b, WASP-82b, and WASP-90b are all inflated, with radii of 1.7-1.8 R[SUB]Jup[/SUB]. All three orbit hot stars, of type F5-F7, with orbits of 1.8-3.9 d, and all three stars have evolved, post-main-sequence radii (1.7-2.2 R[SUB]⊙[/SUB]). Thus the three planets fit a known trend of hot Jupiters that receive high levels of irradiation being highly inflated. We caution, though, about the presence of a selection effect, in that non-inflated planets around ~2 R[SUB]⊙[/SUB] post-MS stars can often produce transits too shallow to be detected by the ground-based surveys that have found the majority of transiting hot Jupiters. Tables of the photometry and radial velocity are only available at the CDS via anonymous ftp to <A href="http://cdsarc.u-strasbg.fr">http://cdsarc.u-strasbg.fr</A> (ftp://130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/585/A126">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/585/A126</A> [less ▲]

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See detailOverview of the Analytical Lifecycle of Supercritical Fluid Chromatography Methods
Andri, Bertyl ULg; Dispas, Amandine ULg; Marini Djang'Eing'A, Roland ULg et al

in American Journal of Analytical Chemistry (2016), 7

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See detailImprovement of TiN nanoparticles EPD inducing steric stabilization in non-aqueous suspensions
Mendoza Gallego, Carlos ULg; González, Zoilo; Castro, Yolanda et al

in Journal of the European Ceramic Society (2016), 36(2), 307-317

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See detailThe effects of a documentary film about schizophrenia on cognitive, affective and behavioural aspects of stigmatisation
Thonon, Bénédicte ULg; Pletinx, Amandine; Grandjean, Allison et al

in Journal of Behavior Therapy and Experimental Psychiatry (2016), 50

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to ... [more ▼]

Background and Objectives: Stereotypes about schizophrenia may lead to prejudicial attitudes and discrimination with debilitating effects on people diagnosed with schizophrenia. There is thus a need to develop interventions aiming to prevent, reduce or eliminate such stereotypes. The aim of this study was to evaluate the effects of a documentary film on schizophrenia on cognitive, affective and behavioural aspects of stigmatisation. Methods: Forty-nine participants were assessed on measures of stereotypes and social distance, and on the Model of Stereotype Content, which includes measures of stereotypes, emotional reactions and behavioural tendencies. Participants were randomly assigned into either a condition in which they viewed the documentary film (Film group), or into a control condition in which no intervention was conducted (Control group). Results: Only participants in the Film group revealed a significant decrease of negative stereotypes (Dangerousness and Unpredictability) and desired Social distance, and a significant increase in the perception of sociability in persons with schizophrenia. Limitations: Small sample size and its reduced generalizability are the main limitations in this study. Conclusions: These findings suggest that a documentary film promoting indirect contact with people diagnosed with schizophrenia is a promising tool to prevent and reduce stigmatisation regarding schizophrenia. [less ▲]

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See detailHigh Prevalence of Plasmodium falciparum Infection in Asymptomatic Individuals from the Democratic Republic of the Congo
Mvumbi, Dieudonné; Bobanga, Thierry; Melin, Pierrette ULg et al

in Malaria Research and Treatment (2016), 2016

Malaria remains a major public health problem in the Democratic Republic of Congo (DRC) with 14 million cases reported by the WHOMalaria Report in 2014. Asymptomaticmalaria cases are known to be prevalent ... [more ▼]

Malaria remains a major public health problem in the Democratic Republic of Congo (DRC) with 14 million cases reported by the WHOMalaria Report in 2014. Asymptomaticmalaria cases are known to be prevalent in endemic areas and are generally untreated,resulting in a significant source of gametocytes that may serve as reservoir of disease transmission. Considering that microscopycertainly underestimates the prevalence of Plasmodium infections within symptomatic carriers and that PCR assays are currentlyrecognized as the most sensitive methods for Plasmodium identification, this study was conducted to weigh the asymptomatic carriage in DRC by a molecular method. Six provinces were randomly selected for blood collection in which 80 to 100 individuals were included in the study. Five hundred and eighty blood sampleswere collected andmolecular diagnosiswas performed. Globally, almost half of the samples collected from asymptomatic individuals (280/580; 48.2%) had Plasmodium infections and the most species identified was P. falciparum alone in combination with P. malariae. The high prevalence reported here should interpellate the bodies involved in malaria control in DR Congo to take into account asymptomatic carriers in actions taken and consider asymptomatic malaria as a major hurdle for malaria elimination. [less ▲]

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See detailDoes the Budyko curve reflect a maximum power state of hydrological systems? A backward analysis
Westhoff, Martijn ULg; Zehe, Erwin; Archambeau, Pierre ULg et al

in Hydrology and Earth System Sciences (2016), 20

Almost all catchments plot within a small envelope around the Budyko curve. This apparent behaviour suggests that organizing principles may play a role in the evolution of catchments. In this paper we ... [more ▼]

Almost all catchments plot within a small envelope around the Budyko curve. This apparent behaviour suggests that organizing principles may play a role in the evolution of catchments. In this paper we applied the thermodynamic principle of maximum power as the organizing principle. In a top-down approach we derived mathematical formulations of the relation between relative wetness and gradients driving runoff and evaporation for a simple one-box model. We did this in an inverse manner such that when the conductances are optimized with the maximum power principle, the steady state behaviour of the model leads exactly to a point on the asymptotes of the Budyko curve. Subsequently, we added dynamics in forcing and actual evaporations, causing the Budyko curve to deviate from the asymptotes. Despite the simplicity of the model, catchment observations compare reasonably well with the Budyko curves subject to observed dynamics in rainfall and actual evaporation. Thus by constraining the model with the asymptotes of the Budyko curve we were able to derive more realistic values of the aridity and evaporation index without any calibration parameter. Future work should focus on better representing the boundary conditions of real catchments and eventually adding more complexity to the model. [less ▲]

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See detailOsteoporosis and sarcopenia: two diseases or one?
Reginster, Jean-Yves ULg; Beaudart, Charlotte ULg; Buckinx, Fanny ULg et al

in Current Opinion in Clinical Nutrition & Metabolic Care (2016), 19(1), 31-6

Purpose of review This article reviews recently published evidence for common pathways explaining bone and muscle wasting in normal ageing and pathological conditions. Recent findings Numerous studies ... [more ▼]

Purpose of review This article reviews recently published evidence for common pathways explaining bone and muscle wasting in normal ageing and pathological conditions. Recent findings Numerous studies support the concept of a bone–muscle unit, where constant cross-talking between the two tissues takes place, involving molecules released by the skeletal muscle secretome, which affects bone, and osteokines secreted by the osteoblasts and osteocytes, which, in turn, impact muscle cells. Summary New chemical entities aiming at concomitantly treating osteoporosis and sarcopenia could be developed by targeting pathways that centrally regulate bone and muscle or emerging pathways that facilitate the communication between the two tissues. [less ▲]

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See detailDynamical thermalization in Bose-Hubbard systems
Schlagheck, Peter ULg; Shepelyansky, Dima L.

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2016), 93

We numerically study a Bose-Hubbard ring of finite size with disorder containing a finite number of bosons that are subject to an on-site two-body interaction. Our results show that moderate interactions ... [more ▼]

We numerically study a Bose-Hubbard ring of finite size with disorder containing a finite number of bosons that are subject to an on-site two-body interaction. Our results show that moderate interactions induce dynamical thermalization in this isolated system. In this regime the individual many-body eigenstates are well described by the standard thermal Bose-Einstein distribution for well-defined values of the temperature and the chemical potential, which depend on the eigenstate under consideration. We show that the dynamical thermalization conjecture works well at both positive and negative temperatures. The relations to quantum chaos, quantum ergodicity, and the Åberg criterion are also discussed. [less ▲]

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See detailIdentification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer.
Umelo, Ijeoma ULg; Noeparast, Amir; Chen, Gang et al

in Oncotarget (2016), 7(3), 3068-83

Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal growth factor (HER) family of receptors have been implicated in the development and progression of non-small cell ... [more ▼]

Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal growth factor (HER) family of receptors have been implicated in the development and progression of non-small cell lung cancer (NSCLC). However, no conclusive reports have described pathogenic mutations in kinase-impaired HER3. Here, we report a case of an advanced chemotherapy-resistant NSCLC, harboring a novel HER3V855A somatic mutation homologous to the EGFRL858Ractivating mutation. Co-expression of HER3V855A and wild-type HER2 enhances ligand-induced transformation of murine and human cell lines, while HER-targeted inhibitors potently suppress mutant HER3 activity. Consistent with these observations, in silico computational modeling predicts that mutant V855A alters the kinase domain and c-terminal end of the HER3 protein. Taken together, these findings provide a basis for the clinical exploration of targeted therapies in HER3 mutant NSCLC and by extrapolation, in other cancers that more frequently carry somatic HER3 mutations. [less ▲]

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See detailLE CAS CLINIQUE DU MOIS Thrombose veineuse ovarienne gauche et extension à la veine rénale
JEAN, FLORENCE; CLAUDOT, A.; ISTACE, B. et al

in Revue Médicale de Liège (2016), 71(1), 17-21

Ovarian vein thrombosis is a rare, but potentially serious postpartum complication. In 80 % of the cases, it occurs on the right side and in less than 6 % on the left side; it is bilateral in 14 % of ... [more ▼]

Ovarian vein thrombosis is a rare, but potentially serious postpartum complication. In 80 % of the cases, it occurs on the right side and in less than 6 % on the left side; it is bilateral in 14 % of cases. The usual clinical features include abdominal pain, fever and leucocytosis. However, the diagnosis is often complicated by other non specific signs and symptoms. Ovarian vein thrombosis may cause sepsis, pulmonary thromboembolism, and thrombosis of the inferior vena cava and the renal vein. The diagnosis can be established by CT scan or nuclear magnetic resonance imaging, which has a high sensitivity and specificity. Treatment for the ovarian vein thrombosis includes antibiotics and anticoagulation. The complications can sometimes be surgically managed. Prompt diagnosis and treatment can decrease the morbidity and the mortality. Nowadays, the fatal issue is rare as the appropriate treatment is quickly instaured. [less ▲]

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See detailSOSpin, a C++ library for Yukawa decomposition in SO(2N) models
Da Silva Simoes, Catarina ULg; Cardoso, Nuno; Emmanuel-Costa, David et al

in Computer Physics Communications (2016)

We present in this paper the SOSpin library, which calculates an analytic decomposition of the Yukawa interactions invariant under SO(2N) in terms of an SU(N) basis. We make use of the oscillator ... [more ▼]

We present in this paper the SOSpin library, which calculates an analytic decomposition of the Yukawa interactions invariant under SO(2N) in terms of an SU(N) basis. We make use of the oscillator expansion formalism, where the SO(2N) spinor representations are expressed in terms of creation and annihilation operators of a Grassmann algebra acting on a vacuum state. These noncommutative operators and their products are simulated in SOSpin through the implementation of doubly-linked-list data structures. These data structures were determinant to achieve a higher performance in the simplification of large products of creation and annihilation operators. We illustrate the use of our library with complete examples of how to decompose Yukawa terms invariant under SO(2N) in terms of SU(N) degrees of freedom for N=2 and 5. We further demonstrate, with an example for SO(4), that higher dimensional field-operator terms can also be processed with our library. Finally, we describe the functions available in SOSpin that are made to simplify the writing of spinors and their interactions specifically for SO(10) models. [less ▲]

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See detailLater learning stages in procedural memory are impaired in children with Specific Language Impairment
Desmottes, Lise ULg; Meulemans, Thierry ULg; Maillart, Christelle ULg

in Research in Developmental Disabilities (2016)

Background According to the Procedural Deficit Hypothesis (PDH), difficulties in the procedural memory system may contribute to the language difficulties encountered by children with Specific Language ... [more ▼]

Background According to the Procedural Deficit Hypothesis (PDH), difficulties in the procedural memory system may contribute to the language difficulties encountered by children with Specific Language Impairment (SLI). Most studies investigating the PDH have used the sequence learning paradigm; however these studies have principally focused on initial sequence learning in a single practice session. Aims The present study sought to extend these investigations by assessing the consolidation stage and longer-term retention of implicit sequence-specific knowledge in 42 children with or without SLI. Methods and procedures Both groups of children completed a serial reaction time task and were tested 24 h and one week after practice. Outcomes and results Results showed that children with SLI succeeded as well as children with typical development (TD) in the early acquisition stage of the sequence learning task. However, as training blocks progressed, only TD children improved their sequence knowledge while children with SLI did not appear to evolve any more. Moreover, children with SLI showed a lack of the consolidation gains in sequence knowledge displayed by the TD children. Conclusions and implications Overall, these results were in line with the predictions of the PDH and suggest that later learning stages in procedural memory are impaired in SLI. [less ▲]

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See detailEffect of Dietary Energy on Productive and Reproductive Performance of Algerian Local Rabbit Does and Their Litters
Saidj, Dahia; Ainbaziz, H.; Salhi, O. et al

in Animal Nutrition and Feed Technology (2016), 16

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See detailĐánh giá tiềm năng bã rượu làm thức ăn chăn nuôi lợn nông hộ tại ba tỉnh phía Bắc
Nguyen Cong, Oanh ULg; Pham Kim, Dang; Vu Dinh, Ton et al

in Journal of Science and Development (2016), 14(1), 79-86

In order to evaluate the potential of the rice distiller’s by-product for use as feed, the chemical composition and nutritive value, and its utilisation in pig production, 120 rice alcohol producers were ... [more ▼]

In order to evaluate the potential of the rice distiller’s by-product for use as feed, the chemical composition and nutritive value, and its utilisation in pig production, 120 rice alcohol producers were surveyed and 18 samples of rice distiller’s by-product were collected from 3 traditional alcohol villages belonging to 3 different provinces in the North of Viet Nam (Hai Duong, Hung Yen and Bac Giang). The study results showed that rice distillers’ by product was produced in large quantity and available the whole year round in households surveyed (8.266 kg DM/household/year). The majority of this by-product was used for pig production. The rice distiller’s by-product use in feed ration varied between 11- 40% DM and 11-50% DM for sows and fattening pigs, respectively. For the sows, this by-product used in diet gradually reduced from pregnancy to milking sows. For the fattening pigs, its by-product is used continuously from piglet to finishing stage. Rice distiller’s by-product was high in protein, NDF (% DM) and energy (28.18%, 29.93% and 4.866,67 kcal/kg, respectively) but low in dry matter (DM) (11.04%). The low pH value (3.19) and high lactic acid ratio (2.31 g/100 g sample) might help improve digestive health and prevent intestinal diseases. [less ▲]

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See detailLa psychothérapie institutionnelle : un processus thérapeutique au service de la régulation émotionnelle et de l'empathie
Triffaux, Jean-Marc ULg; Gernay, Delphine; Servais, Catherine et al

in Encéphale (L') (2016)

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See detailXenobiotic and Immune-Relevant Molecular Biomarkers in Harbor Seals as Proxies for Pollutant Burden and Effects?
Lehnert, Kristina; Ronnenberg, Katrin; Weijs, Liesbeth et al

in Archives of Environmental Contamination & Toxicology (2016), 70(1), 106-120

Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants which ... [more ▼]

Harbor seals are exposed to increasing pressure caused by anthropogenic activities in their marine environment. Persistent organic pollutants (POPs) and trace elements are hazardous contaminants which accumulate in tissues of harbor seals. POPs and trace elements can negatively affect the immune-system and have been reported e.g. to increase susceptibility to viral infections in seals. Biomarkers of the xenobiotic metabolism, cytokines and heat-shock-protein as cell mediators of the immune-system were established to evaluate the impact of environmental stressors on harbor seals. Harbor seals (n=54) were captured on sandbanks in the North Sea during 2009 to 2012. Medicals including hematology were performed, RNAlater blood samples were taken and analyzed using quantitative Polymerase Chain Reaction. Normalized transcript copy numbers were correlated to hematology and POP concentration in blood, and trace metals in blood and fur. [less ▲]

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See detailAcquisition forcée de la mitoyenneté : prise de possession versus réalisation de travaux dans les règles de l'art
Popa, Ruxandra ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2016), 2016(2), 55

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See detailEffects of Methylmercury on Harbour Seal Peripheral Blood Leucocytes In Vitro Studied by Electron Microscopy
Dupont, Aurélie; De Pauw-Gillet, Marie-Claire ULg; Schnitzler, Joseph ULg et al

in Archives of Environmental Contamination & Toxicology (2016), 70(1), 133-142

Methylmercury MeHg is highly immunotoxic and can alter the health status of the harbour seal, Phoca vitulina, from the North Sea. To investigate the mechanism of MeHg-induced toxicity in harbour seal ... [more ▼]

Methylmercury MeHg is highly immunotoxic and can alter the health status of the harbour seal, Phoca vitulina, from the North Sea. To investigate the mechanism of MeHg-induced toxicity in harbour seal lymphocytes, ConA-stimulated peripheral blood leucocytes were exposed in vitro to sub-lethal concentrations of MeHgCl (0.2, 1 and 2 µM) for 72h, and then analysed for their viability and ultrastructure. After 72h of incubation, cells were counted with a propidium iodide staining technique, a metabolic MTS assay was performed, and cells exposed to 1 µM MeHgCl were observed by transmission electron microscopy (TEM). Alive cell numbers decreased with increased MeHgCl concentrations. In presence of ConA and 1µM of MeHgCl, TEM images revealed a higher frequency of apoptotic cells. Exposed cells displayed condensation of the chromatin at the nuclear membrane and mitochondrial damages. The results suggest that in vitro MeHgCl induced apoptosis in harbour seal lymphocytes through a mitochondrial pathway. [less ▲]

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See detailPremière consultation de contraception chez les adolescentes
BELIARD, Aude ULg

in Revue Médicale de Liège (2016), 71(1), 28-33

Adequate contraception prescription is mandatory for teenagers to avoid any unwanted pregnancy. Counselling and description of side effect improve compliance. Use of condom is important to avoid sexually ... [more ▼]

Adequate contraception prescription is mandatory for teenagers to avoid any unwanted pregnancy. Counselling and description of side effect improve compliance. Use of condom is important to avoid sexually transmitted infections. Combined estroprogestin contraception has multiple non-contraceptive benefits, e.g. dysmenorrhea improvement. Familial and personal history is needed before contraception prescription. Further consultation 3 months later has to be planned to evaluate compliance, side effects and to adapt contraception if needed. [less ▲]

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See detailComment je traite... la sténose aortique asymptomatique
MEURICE, Caroline ULg; DULGHERU, Raluca Elena ULg; PIERARD, Luc ULg

in Revue Médicale de Liège (2016), (71), 6-10

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See detailGender differences in variability and extreme scores in an international context
Baye, Ariane ULg; Monseur, Christian ULg

in Large-scale Assessments in Education (2016), 4(1),

This study examines gender differences in the variability of student performance in reading, mathematics and science. Twelve databases from IEA and PISA were used to analyze gender differences within an ... [more ▼]

This study examines gender differences in the variability of student performance in reading, mathematics and science. Twelve databases from IEA and PISA were used to analyze gender differences within an international perspective from 1995 to 2015. Effect sizes and variance ratios were computed. The main results are as follows. (1) Gender differences vary by content area, students’ educational levels, and students’ proficiency levels. The gender differences at the extreme tails of the distribution are often more substantial than the gender differences at the mean. (2) Exploring the extreme tails of the distributions shows that the situation of the weakest males in reading is a real matter of concern. In mathematics and science, males are more frequently among the highest performing students. (3) The “greater male variability hypothesis” is confirmed. [less ▲]

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See detailCost-effectiveness of personalized supplementation with vitamin D-rich dairy products in the prevention of osteoporotic fractures
Ethgen, Olivier ULg; Hiligsmann, Mickaël; Burlet, Nansa et al

in Osteoporosis International (2016), 27

Summary: Titrated supplementations with vitamin D-fortified yogurt, based on spontaneous calcium and vitamin D intakes, can be cost-effective in postmenopausal women with or without increased risk of ... [more ▼]

Summary: Titrated supplementations with vitamin D-fortified yogurt, based on spontaneous calcium and vitamin D intakes, can be cost-effective in postmenopausal women with or without increased risk of osteoporotic fractures. Introduction: The objective of this study is to assess the costeffectiveness of the vitamin D-fortified yogurt given to women with and without an increased risk of osteoporotic fracture. Methods: Avalidated cost-effectiveness microsimulation Markov model of osteoporosis management was used. Three personalized supplementation scenarios to reflect the Ca/Vit D needs taking into account the well-known variations in dietary habits and a possible pharmacological supplementation in Ca/ Vit D, given above or in combination with anti-osteoporosis medications: one yogurt per day, i.e., 400 mg of Ca+200 IU of Vit D (scenario 1 U), two yogurts per day, i.e., 800 mg of Ca+ 400 IU of Vit D (scenario 2 U), or three yogurts per day, i.e., 1, 200 mg of Ca+600 IU of Vit D (scenario 3 U). Results: One yogurt is cost-effective in the general population above the age of 70 years and in all age groups in women with low bone mineral density (BMD) or prevalent vertebral fracture (PVF). The daily intake of two yogurts is cost-effective above 80 years in the general population and above 70 years in the two groups of women at increased risk of fractures. However, an intake of three yogurts per day is only cost-effective above 80 years old in the general population, as well as in women with low BMD or PVF. Conclusions: Our study is the first economic analysis supporting the cost-effectiveness of dairy products, fortified with vitamin D, in the armamentarium against osteoporotic fractures. [less ▲]

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See detailDeterminants of vitamin D supplementation prescription in nursing homes: a survey among general practitioners
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Cavalier, Etienne ULg et al

in Osteoporosis International (2016), 27

Abstract Summary A total of 119 GPs participated to a survey aimed to assess the profile and determinants of vitamin D supplementation prescription in nursing homes. Among the respondent GPs, 65 (54.6 ... [more ▼]

Abstract Summary A total of 119 GPs participated to a survey aimed to assess the profile and determinants of vitamin D supplementation prescription in nursing homes. Among the respondent GPs, 65 (54.6 %) systematically prescribe vitamin D to their institutionalized patients and the 54 (45.4 %) others prescribe only sometimes. Introduction The aim of this study is to assess the profile and determinants of vitamin D supplementation prescription in nursing homes. Methods General practitioners (GPs) having at least one patient in a nursing home in Liège, Belgium, were asked to complete the survey. Results A total of 119 GPs participated in the survey. Among the respondent GPs, 65 (54.6 %) systematically prescribe vitamin D to their institutionalized patients and the 54 (45.4 %) others prescribe only sometimes. The main reasons for prescribing vitamin D cited by GPs who do so systematically are as follows: because they believe nursing home residents are mostly deficient in vitamin D status (92.1 %), because they believe that vitamin D supplementation prevents osteoporotic fractures (77.8 %), and because vitamin D supplementation is recommended by various scientific societies (38.1 %). GPs who only prescribe vitamin D supplementation in some patients mainly do so following a diagnosis of osteoporosis (82.4 %), on the basis the 25(OH)D level (78.4 %), in the case of history of fracture (54.9 %) or after a recent fracture (43.4 %). Surprisingly, 16 physicians (31.4 %) only prescribe vitamin D when they think of it. Interestingly, while 40.7% of GPs always prescribe the same dose of vitamin D, the remaining 59.3 % prescribe a dose that will mainly depend on the results of the 25(OH)D level (94.0 %), the patient’s bone health (49.3 %), or history of fracture (43.3 %). Conclusions More than half of GPs systematically prescribe vitamin D to their patients living in nursing homes. The other GPs usually prescribe vitamin D following the result of the vitamin D status or after a diagnosis of osteoporosis. [less ▲]

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See detailProjecting alternative urban growth patterns: The development and application of a remote sensing assisted calibration framework for the Greater Dublin Area
Van de Voorde, Tim; van der Kwast, Johannes; Poelmans, Lien et al

in Ecological Indicators (2016), 60

Land use change models are powerful tools that allow planners and policy makers to assess the long-term spatial and environmental impacts of their decisions. In order for these models to produce a ... [more ▼]

Land use change models are powerful tools that allow planners and policy makers to assess the long-term spatial and environmental impacts of their decisions. In order for these models to produce a realistic output, they should be properly calibrated. This is usually achieved by comparing simulated land-use maps of dates in the past to reference land-use maps of a corresponding date. As land-use data are often not readily or frequently available, we propose a two-stage calibration framework that includes existing land-use maps as well as remote sensing derived maps of the urban extent. Urban growth patterns for the Dublin area represented by remote sensing based maps were compared to simulated growth using spatial metrics in order to fine-tune the calibration of the MOLAND urban growth model of Dublin. We then used the calibrated model to forecast future urban growth according to four urban planning scenarios that have been defined for the Strategic Environmental Assessment of the Greater Dublin Area. We examined a selection of spatial metrics in order to determine their sensitivity to differences in spatial patterns between simulated and remote sensing derived data. We also investigated whether these metrics are useful to characterise future changes in the urban spatial structure that ensue from the planning scenarios. We found that with the exception of some metrics that strongly respond to differences in the amount of urban land, most metrics showed similar trends for simulated and remote sensing derived maps. Most metrics were also able to distinguish the growth patterns induced by the different spatial planning scenarios. The “business as usual scenario” in particular showed a clearly distinct trend compared to the other scenarios. We could also conclude that the urban growth pattern of Dublin as observed from both the remote sensing derived maps and the simulated maps of future land use seems to confirm the theory of alternating phases of diffusive growth and coalescence. [less ▲]

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See detailVaricella paediatric hospitalisations in Belgium: a 1-year national survey.
Blumental, Sophie; Sabbe, Martine; Lepage, Philippe et al

in Archives of disease in childhood (2016), 101(1), 16-22

BACKGROUND: Varicella universal vaccination (UV) has been implemented in many countries for several years. Nevertheless, varicella UV remains debated in Europe and few data are available on the real ... [more ▼]

BACKGROUND: Varicella universal vaccination (UV) has been implemented in many countries for several years. Nevertheless, varicella UV remains debated in Europe and few data are available on the real burden of infection. We assessed the burden of varicella in Belgium through analysis of hospitalised cases during a 1-year period. METHODS: Data on children admitted to hospital with varicella were collected through a national network from November 2011 to October 2012. Inclusion criteria were either acute varicella or related complications up to 3 weeks after the rash. RESULTS: Participation of 101 hospitals was obtained, covering 97.7% of the total paediatric beds in Belgium. 552 children were included with a median age of 2.1 years. Incidence of paediatric varicella hospitalisations reached 29.5/10(5) person-years, with the highest impact among those 0-4 years old (global incidence and odds of hospitalisation: 79/10(5) person-years and 1.6/100 varicella cases, respectively). Only 14% (79/552) of the cohort had an underlying chronic condition. 65% (357/552) of children had >/=1 complication justifying their admission, 49% were bacterial superinfections and 10% neurological disorders. Only a quarter of children (141/552) received acyclovir. Incidence of complicated hospitalised cases was 19/10(5) person-years. Paediatric intensive care unit admission and surgery were required in 4% and 3% of hospitalised cases, respectively. Mortality among Belgian paediatric population was 0.5/10(6) and fatality ratio 0.2% among our cohort. CONCLUSIONS: Varicella demonstrated a substantial burden of disease in Belgian children, especially among the youngest. Our thorough nationwide study, run in a country without varicella UV, offers data to support varicella UV in Belgium. [less ▲]

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See detailL’infraction d’obstacle à la surveillance sous le spectre du droit au silence et du droit de ne pas s’auto-incriminer
Michiels, Olivier ULg; Falque, Géraldine ULg

in Orientations : la Revue du Droit Social et de la Gestion du Personnel (2016), (2006/1), 2-11

L'article fait le point sur le contrôle de l’application des lois sociales par les inspecteurs sociaux et le délit d’obstacle à la surveillance envisagé sous l'angle du droit au silence et du droit de ne ... [more ▼]

L'article fait le point sur le contrôle de l’application des lois sociales par les inspecteurs sociaux et le délit d’obstacle à la surveillance envisagé sous l'angle du droit au silence et du droit de ne pas s'auto-incriminer. Il envisage encore la cohabitation entre le délit d'obstacle et le droit au silence sous l’angle de la jurisprudence de la Cour européenne des droits de l’homme et du droit interne. [less ▲]

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See detailL'observation foncière en France, à Bruxelles et en Flandre
Hendrickx, Sébastien ULg; Sarciat, Jordane ULg; Halleux, Jean-Marie ULg

in Notes de recherche - Conférence Permanente du Développement Territorial Région Wallonne (2016), 64

Depuis quelques années, un intérêt accru se développe pour l’observation des marchés fonciers et la recherche de gisements fonciers, indispensables à une mise en œuvre efficace des politiques ... [more ▼]

Depuis quelques années, un intérêt accru se développe pour l’observation des marchés fonciers et la recherche de gisements fonciers, indispensables à une mise en œuvre efficace des politiques d’aménagement du territoire et des politiques sectorielles. La note de recherche n° 64 s’intéresse aux pratiques d’observation dans les territoires adjacents à la Wallonie et plus exactement aux outils développés en France, en Flandre et en Région de Bruxelles-Capitale. L’analyse de ces différents cas a mis en exergue l'avance évidente de nos voisins sur ces problématiques et permet d'apprécier l’utilité d’une connaissance territoriale accrue pour l’élaboration des stratégies de développement territorial et pour la prise de décision politique. Elle aboutit à diverses recommandations relatives à l’amélioration du système d’informations foncières et des politiques foncières en Wallonie. [less ▲]

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See detailNos différences, une richesse
RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète (2016), 59

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See detailL'intentionnalité cognitive et ses modes. Reinach critique de Brentano
Dewalque, Arnaud ULg

in Philosophie (2016), 128

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai ... [more ▼]

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai mon attention sur certaines divergences significatives entre Reinach et Brentano. Après quelques réflexions introductives (§§ 1-2), j’examinerai plus exactement les questions suivantes : quels sont les motifs théoriques qui ont conduit Reinach à s’écarter de la théorie brentanienne du jugement (§§ 3-4) ? Et que retenir de ses analyses aujourd’hui (§§ 5-6) ? [less ▲]

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See detailEtude de cas: l'attentat au Musée juif de Bruxelles
Debras, François ULg

in Politique : Revue de Débats (2016), 93

L’attaque soudaine d’un homme qui fait irruption dans un lieu public et tue quatre individus est angoissante. Les catastrophes, les drames et les malheurs qui frappent la société sont porteurs de ... [more ▼]

L’attaque soudaine d’un homme qui fait irruption dans un lieu public et tue quatre individus est angoissante. Les catastrophes, les drames et les malheurs qui frappent la société sont porteurs de nombreuses questions : qui, comment, pourquoi, dans quel but,… ? Les théories du complot permettent de répondre à un besoin social, celui de comprendre. Le complot est d’autant plus attirant et convaincant qu’il apporte une réponse simple, globale et dépouillée de toute subtilité. [less ▲]

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See detailCross-Modal Decoding of Neural Patterns Associated with Working Memory: Evidence for Attention-Based Accounts of Working Memory
Majerus, Steve ULg; Cowan, Nelson; Peters, Frédéric ULg et al

in Cerebral Cortex (2016), 26

Recent studies suggest common neural substrates involved in verbal and visual working memory (WM), interpreted as reflecting shared attention-based, short-term retention mechanisms. We used a machine ... [more ▼]

Recent studies suggest common neural substrates involved in verbal and visual working memory (WM), interpreted as reflecting shared attention-based, short-term retention mechanisms. We used a machine-learning approach to determine more directly the extent to which common neural patterns characterize retention in verbal WM and visual WM. Verbal WM was assessed via a standard delayed probe recognition task for letter sequences of variable length. Visual WM was assessed via a visual array WM task involving the maintenance of variable amounts of visual information in the focus of attention. We trained a classifier to distinguish neural activation patterns associated with high- and low-visual WM load and tested the ability of this classifier to predict verbal WM load (high–low) from their associated neural activation patterns, and vice versa. We observed significant between-task prediction of load effects during WM maintenance, in posterior parietal and superior frontal regions of the dorsal attention network; in contrast, between-task prediction in sensory processing cortices was restricted to the encoding stage. Furthermore, between-task prediction of load effects was strongest in those participants presenting the highest capacity for the visual WM task. This study provides novel evidence for common, attention-based neural patterns supporting verbal and visual WM. [less ▲]

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See detailRe-visiting plant plasma membrane lipids in tobacco: a focus on sphingolipids
Cacas, Jean Luc; Buré, Corinne; Grosjean, Kevin et al

in Plant Physiology (2016), 170

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See detailEffect of coil orientation on strength-duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulation
D'Ostilio, Kevin ULg; Goetz, Stefan; Hannah, Ricci et al

in Clinical Neurophysiology (2016), 1

Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central ... [more ▼]

Objective: To compare the strength-duration (S-D) time constants of motor cortex structures activated by current pulses oriented posterior-anterior (PA) or anterior-posterior (AP) across the central sulcus. Methods: Motor threshold and input–output curve, along with motor evoked potential (MEP) latencies, of first dorsal interosseus were determined at pulse widths of 30, 60, and 120 μs using a controllable pulse parameter (cTMS) device, with the coil oriented PA or AP. These were used to estimate the S-D time constant and we compared with data for responses evoked by cTMS of the ulnar nerve at the elbow. Results: The S-D time constant with PA was shorter than for AP stimulation (230.9 ± 97.2 vs. 294.2 ± 90.9 us; p<0.001). These values were similar to those calculated after stimulation of ulnar nerve (197 ± 47us). MEP latencies to AP, but not PA stimulation were affected by pulse width, showing longer latencies following short duration stimuli. Conclusion: PA and AP stimuli appear to activate the axons of neurons with different time constants. Short duration AP pulses are more selective than longer pulses in recruiting longer latency corticospinal output. [less ▲]

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See detailQuand la force enfonce des portes ouvertes. Analyse du traitement de Star Wars Episode VII par la critique professionnelle et amateure.
Krywicki, Boris ULg

in Culture, le Magazine Culturel de l'Université de Liège (2016)

On a rarement aperçu des phénomènes cinématographiques de l’ampleur de Star Wars. La plupart des séances étaient déjà complètes plusieurs semaines avant la sortie du dernier épisode. Les spectateurs sont ... [more ▼]

On a rarement aperçu des phénomènes cinématographiques de l’ampleur de Star Wars. La plupart des séances étaient déjà complètes plusieurs semaines avant la sortie du dernier épisode. Les spectateurs sont tous conquis en amont par ce messie monolithique. Quand il s'agit d'aborder un film-événement comme Star Wars, la critique de cinéma se cherche. Les timides tentatives de la rigide presse professionnelle qui hésite toujours à critiquer les productions hollywoodiennes font face à des vidéos de youtubeurs décomplexés. Cet article analyse les contrats de lecture de ces différents énonciateurs et le lecteur-modèle qu'ils envisagent pour traiter de Star Wars Episode VII. [less ▲]

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See detailarchiDART: an R package for the automated computation of plant root architectural traits
Delory, Benjamin ULg; Baudson, Caroline ULg; Brostaux, Yves ULg et al

in Plant and Soil (2016), 398(1), 351-365

Background and Aims In order to analyse root system architectures (RSAs) from captured images, a variety of manual (e.g. Data Analysis of Root Tracings, DART), semi-automated and fully automated software ... [more ▼]

Background and Aims In order to analyse root system architectures (RSAs) from captured images, a variety of manual (e.g. Data Analysis of Root Tracings, DART), semi-automated and fully automated software packages have been developed. These tools offer complementary approaches to study RSAs and the use of the Root System Markup Language (RSML) to store RSA data makes the comparison of measurements obtained with different (semi-) automated root imaging platforms easier. The throughput of the data analysis process using exported RSA data, however, should benefit greatly from batch analysis in a generic data analysis environment (R software). Methods We developed an R package (archiDART) with five functions. It computes global RSA traits, root growth rates, root growth directions and trajectories, and lateral root distribution from DART-generated and/or RSML files. It also has specific plotting functions designed to visualise the dynamics of root system growth. Results The results demonstrated the ability of the package’s functions to compute relevant traits for three contrasted RSAs (Brachypodium distachyon [L.] P. Beauv., Hevea brasiliensis Müll. Arg. and Solanum lycopersicum L.). Conclusions This work extends the DART software package and other image analysis tools supporting the RSML format, enabling users to easily calculate a number of RSA traits in a generic data analysis environment. [less ▲]

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See detailSmall-Angle Neutron Scattering investigation of cholesterol-doped DMPC liposomes interacting with β-cyclodextrin
Joset, Arnaud ULg; Grammenos, Angeliki; Hoebeke, Maryse ULg et al

in Journal of Inclusion Phenomena and Macrocyclic Chemistry (2016), 84(1), 153-161

The Small-Angle Neutron Scattering technique (SANS) has been applied to characterize the influence of a randomly methylated β–cyclodextrin (CD), called RAMEB, on dimyristoylphosphatidylcholine (DMPC ... [more ▼]

The Small-Angle Neutron Scattering technique (SANS) has been applied to characterize the influence of a randomly methylated β–cyclodextrin (CD), called RAMEB, on dimyristoylphosphatidylcholine (DMPC) liposomes doped with cholesterol. From the modelling of the experimental neutron scattering crosssections, the detailed response of the vesicle structure upon addition of increasing amounts of RAMEB up to 30 mM has been assessed. This study has been performed below and above the DMPC bilayer phase transition temperature and shows that cholesterol extraction by RAMEB is linked to a decrease of the average radius and of the aggregation number of the vesicles. This extraction takes place in a dose-dependent way until a more monodisperse population of cholesterol-free liposomes was obtained. In addition, the bilayer thickness evolution was inferred, as well as the liposome coverage by RAMEB. [less ▲]

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See detailGenetic diversity and population structure of the Eurosian otte (Lutra lutra) in France
Geboes, Anne-Laure ULg; Rosoux, René; Lemarchand, Charles et al

in Mammal Research (2016), 61(1),

During the last century, the Eurasian otter (Lutra lutra) suffered a dramatic decline in Europe. In France, the same pattern of sharp decline was observed with local extinctions in many regions. Before ... [more ▼]

During the last century, the Eurasian otter (Lutra lutra) suffered a dramatic decline in Europe. In France, the same pattern of sharp decline was observed with local extinctions in many regions. Before the recolonisation process, two main populations still remained along the Atlantic coast and in the Massif Central. To investigate the impact of this decline on the genetic diversity and structure of the French otter population, tissue samples of 144 otter carcasses from road kills that were found during 1992–2011 along the Atlantic coast and in the Massif Central were used. They were analysed using 10 microsatellites loci. Observed (Ho = 0.64) and expected heterozygosity (He = 0.62) were moderate, but consistent with results found in other European populations. The bottleneck test showed an excess of heterozygotes, providing evidence of a recent decline. There was evidence for weak but significant allelic frequencies divergence between otters from the Atlantic coast and those from the Massif Central (Fst=0.040, p<0.05), probably resulting from their isolation prior to the recolonisation process. As the French otter population has been expanding for several years, genetic intermixing is now occurring. Although this expansion has not yet genetically homogenised all populations, this is may be a matter a time. [less ▲]

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See detailOrder short-term memory capacity predicts nonword reading and spelling in first and second grade
Binamé, Florence ULg; Poncelet, Martine ULg

in Reading and Writing (2016), 1

Recent theories of short-term memory (STM) distinguish between item information, which reflects the temporary activation of long-term representations stored in the language system, and serial-order ... [more ▼]

Recent theories of short-term memory (STM) distinguish between item information, which reflects the temporary activation of long-term representations stored in the language system, and serial-order information, which is encoded in a specific representational system that is independent of the language network. Some studies examining the relationship between reading acquisition and verbal STM for order and item information separately in beginning readers have found that order STM capacity is independently predictive of nonword decoding abilities in first grade, but item STM is not. In this longitudinal study, we first aimed to explore whether this finding also holds for nonword spelling abilities. We also sought to determine whether order STM capacity remains an independent predictor of nonword decoding and spelling abilities in the second year of reading instruction. For this purpose, 70 typically developing children were followed over 3 years, from kindergarten to second grade. In kindergarten, children were administered order and item STM tasks and phonological awareness tasks, in addition to tasks assessing letter name knowledge, vocabulary knowledge, and nonverbal reasoning. In first and second grades, the children’s word and nonword reading and spelling abilities were assessed. The results revealed that order STM capacity was a robust independent predictor of nonword reading and spelling abilities in first and second grade, but was not related to the abilities to read and spell words. The specific role of order STM in the acquisition of the sublexical reading and spelling routes is discussed. [less ▲]

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See detailPopulatieonderzoek naar de Hazelmuis in de Voerstreek
Verbeylen, Goedele; Mouton, Alice ULg; Driessens, Gerald et al

in De Levende Natuur (2016), (numero 1),

The Hazel dormouse (Muscardinus avellanarius) is a habitat specialist that prefers dense shrub and tree vegetation and needs a high diversity of food plants on a limited area. Due to habitat degradation ... [more ▼]

The Hazel dormouse (Muscardinus avellanarius) is a habitat specialist that prefers dense shrub and tree vegetation and needs a high diversity of food plants on a limited area. Due to habitat degradation and fragmentation the Flemish distribution area of this critically endangered species has been reduced to the eastern part of the municipality of Voeren, where it forms a cross-border population with the Dutch Hazel dormice. Since 2003 the Mammal Working Group of Natuurpunt studies the remaining Flemish population to find out more about population parameters, habitat use, the influence of habitat quality and management actions. In 2007 a standardised monitoring started by counting autumnal nests along fixed transects. In 2013 an intensive capture-mark-recapture study was set up based on nest box and nest tube checks and live-trapping on custom made hanging platforms; also a first test with radiocollars took place. The information gathered from the combination of all these methods will be used to validate the monitoring method and to formulate better protection measures. First results show that late summer and autumn should not be considered as the main reproduction period, at least not in an early year like 2014 when first young were already born at the beginning of May. Hazel dormice do not only cross significant barriers like the railway during dispersal, but also do this regularly during their nightly movements within their home range. Expansion of the population on a location with sufficient connectivity seems to be hampered by a too low population density resulting from insufficient habitat quality and (in this case) a high predation pressure by house cats. On the scale of the Meuse-Rhine Euregion, genetic analyses carried out by the University of Liège reveal four genetically isolated clusters, for which a vision to interconnect these was computed in the Interreg-project ‘Habitat Euregio’. [less ▲]

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See detailA numerical study of hypoelastic and hyperelastic large strain viscoplastic Perzyna type models
Careglio, Claudio; Canales Cardenas, Cristian ULg; García Garino, Carlos et al

in Acta Mechanica (2016)

For the case ofmetalswith large viscoplastic strains, it is necessary to define appropriate constitutive models in order to obtain reliable results from the simulations. In this paper, two large strain ... [more ▼]

For the case ofmetalswith large viscoplastic strains, it is necessary to define appropriate constitutive models in order to obtain reliable results from the simulations. In this paper, two large strain viscoplastic Perzyna type models are considered. The first constitutive model has been proposed by Ponthot, and the elastic response is based on hypoelasticity. In this case, the kinematics of the constitutive model is based on the additive decomposition of the rate deformation tensor. The second constitutive model has been proposed by García Garino et al., and the elastic response is based on hyperelasticity. In this case, the kinematics of the constitutive model is based on the multiplicative decomposition of the deformation gradient tensor. In both cases, the resultant numerical models have been implemented in updated Lagrangian formulation. In this work, global and local numerical results of the mechanical response of both constitutive models are analyzed and discussed. To this end, numerical experiments are performed and different parameters of the constitutive models are tested in order to study the sensitivity of the resultant algorithms. In particular, the evolution of the reaction forces, the effective plastic strain, the deformed shapes and the sensitivity of the numerical results to the finite element mesh discretization have been compared and analyzed. The obtained results show that both models have a very good agreement and represent very well the characteristic of the viscoplastic constitutive model. [less ▲]

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See detailPre-employement examination for low back risk in workers exposesd to manual handling of loads : French guidelines
PETIT, Audrey; ROUSSEAU, Sandrine; HUEZ, Jean-François et al

in International Archives of Occupational and Environmental Health (2016), 89

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See detailElectrical resistivity tomography to monitor enhanced biodegradation of hydrocarbons with Rhodococcus erythropolis T902.1 at a pilot scale
Masy, Thibaut ULg; Caterina, David; Tromme, Oliver et al

in Journal of Contaminant Hydrology (2016), 184

Petroleum hydrocarbons (HC) represent the most widespread contaminants and in-situ bioremediation remains a competitive treatment in terms of cost and environmental concerns. However, the efficiency of ... [more ▼]

Petroleum hydrocarbons (HC) represent the most widespread contaminants and in-situ bioremediation remains a competitive treatment in terms of cost and environmental concerns. However, the efficiency of such a technique (by biostimulation or bioaugmentation) strongly depends on the environment affected and is still difficult to predict a priori. In order to overcome these uncertainties, Electrical Resistivity Tomography (ERT) appears as a valuable non-invasive tool to detect soil heterogeneities and to monitor biodegradation. The main objective of this study was to isolate an electrical signal linked to an enhanced bacterial activity with ERT, in an aged HC-contaminated clayey loam soil. To achieve this, a pilot tank was built to mimic field conditions. Compared to a first insufficient biostimulation phase, bioaugmentation with Rhodococcus erythropolis T902.1 led to a HC depletion of almost 80% (6900 to 1600 ppm) in 3 months in the center of the contaminated zone, where pollutants were less bioavailable. In the meantime, lithological heterogeneities and microbial activities (growth and biosurfactant production) were successively discriminated by ERT images. In the future, this cost-effective technique should be more and more transferred to the field in order to monitor biodegradation processes and assist in selecting the most appropriate remediation technique. [less ▲]

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See detailULTRASONOGRAPHIC FINDINGS IN 13 HORSES WITH LYMPHOMA
Janvier, Valentin; Evrard, Laurence ULg; Cerri, Simona ULg et al

in Veterinary Radiology & Ultrasound (2016), 57(1), 65-74

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See detailFLOR-ID: an interactive database of flowering-time gene networks in Arabidopsis thaliana
Bouché, Frédéric ULg; Lobet, Guillaume ULg; Tocquin, Pierre ULg et al

in Nucleic Acids Research (2016), 44(Database), 11671171

Flowering is a hot topic in Plant Biology and important progress has been made in Arabidopsis thaliana toward unravelling the genetic networks involved. The increasing complexity and the explosion of ... [more ▼]

Flowering is a hot topic in Plant Biology and important progress has been made in Arabidopsis thaliana toward unravelling the genetic networks involved. The increasing complexity and the explosion of literature however require development of new tools for information management and update. We therefore created an evolutive and interactive database of flowering time genes, named FLOR-ID (Flowering-Interactive Database), that is available freely at http://www.flor-id.org. The hand-curated database contains information on 306 genes and links to 1595 publications gathering the work of more than 4500 authors. Gene function and interactions within the flowering pathways were inferred from the analysis of related publications, included in the database and translated into interactive manually drawn snapshots. [less ▲]

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See detailCharacterizing the morphology of suburban settlements: a method based on a semi-automatic classification of building clusters
de Smet, Fabian; Teller, Jacques ULg

in Landscape Research (2016), 41(1), 113-130

Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of ... [more ▼]

Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of much debate amongst scientists. The present article takes the view that, beyond measuring and delineating suburban areas, more efforts should be directed to qualifying the morphology of built settlements within these areas. Therefore it proposes a method based on a semi-automatic classification system of building clusters, designed to describe and interpret the phenomenon from a morphological perspective. This method is based on a combination of field surveys with numerical analyses of digital land cadastre maps. The application of this classification system to the suburban area around Liege reveals that, far from developing in a complete indifference of local conditions, contemporary suburban settlements are influenced by landscape structures inherited from the past. [less ▲]

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See detailProvenance of Ichthyosaura alpestris (Caudata: Salamandridae) introductions to France and New Zealand assessed by mitochondrial DNA analysis
Arntzen, Jan W.; King, Tania M.; Denoël, Mathieu ULg et al

in The Herpetological Journal (2016), 26(1), 49-56

The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a ... [more ▼]

The last century has seen an unparalleled movement of species around the planet as a direct result of human activity, which has been a major contributor to the biodiversity crisis. Amphibians represent a particularly vulnerable group, exacerbated by the devastating effects of chytrid fungi. We report the malicious translocation and establishment of the alpine newt (Ichthyosaura alpestris) to its virtual antipode in North Island of New Zealand. We use network analysis of mitochondrial DNA haplotypes to identify the original source population as I. a. apuana from Tuscany, Italy. Additionally, a population in southern France, presumed to be introduced, is identified as I. a. alpestris from western Europe. However, the presence of two differentiated haplotypes suggests a mixed origin. This type of analysis is made possible by the recent availability of a phylogenetic analysis of the species throughout its natural range. We discuss the particulars of both introductions. [less ▲]

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See detailThe Relationship between the Profile of Manager and Management Accounting Practices in Tunisian SMIs
Ghorbel, Jihene ULg

in International Journal of Academic Research in Accounting, Finance and Management Sciences (2016), 6(1), 61-72

In today’s changing environment, SMEs must strengthen their competitiveness and credibility with all their external partners. So to survive and prosper, managers need adequate management practices in ... [more ▼]

In today’s changing environment, SMEs must strengthen their competitiveness and credibility with all their external partners. So to survive and prosper, managers need adequate management practices in order to provide relevant accounting information. This paper examines the effect of profile of manager on management accounting practices which was defined in terms of traditional management accounting, modern management accounting and management accounting practices related to export. As to the profile of manager, it is defined by age, type of training and experience. To validate the hypotheses, a multiple linear regression method is used. The data is collected by questionnaire from 221 Tunisian manufacturing SMEs. The findings indicate that the profile of manager affect in part the use of management accounting practices. [less ▲]

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See detailShaping Pulses to Control Bistable Systems: Analysis, Computation and Counterexamples
Sootla, Aivar ULg; Oyarzun, Diego; Angeli, David et al

in Automatica (2016), 63

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See detailEffects of seed traits variation on seedling performance of the invasive weed, Ambrosia artemisiifolia L.
Ortmans, William ULg; Mahy, Grégory ULg; Monty, Arnaud ULg

in Acta Oecologica: International Journal of Ecology (2016), 71

Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for ... [more ▼]

Seedling performance can determine the survival of a juvenile plant and impact adult plant performance. Understanding the factors that may impact seedling performance is thus critical, especially for annuals, opportunists or invasive plant species. Seedling performance can vary among mothers or populations in response to environmental conditions or under the influence of seed traits. However, very few studies have investigated seed traits variations and their consequences on seedling performance. Specifically, the following questions have been addressed by this work: 1) How the seed traits of the invasive Ambrosia artemisiifolia L. vary among mothers and populations, as well as along the latitude; 2) How do seed traits influence seedling performance; 3) Is the influence on seedlings temperature dependent. With seeds from nine Western Europe ruderal populations, seed traits that can influence seedling development were measured. The seeds were sown into growth chambers with warmer or colder temperature treatments. During seedling growth, performance-related traits were measured. A high variability in seed traits was highlighted. Variation was determined by the mother identity and population, but not latitude. Together, the temperature, population and the identity of the mother had an effect on seedling performance. Seed traits had a relative impact on seedling performance, but this did not appear to be temperature dependent. Seedling performance exhibited a strong plastic response to the temperature, was shaped by the identity of the mother and the population, and was influenced by a number of seed traits. [less ▲]

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See detailAn Economic Appraisal of MOOC Platforms: Business Models and Impacts on Higher Education
Jacqmin, Julien ULg; belleflamme, paul

in CESifo Economic Studies (2016), 62(1), 148-169

We use various economic and pedagogical concepts to understand the specificities of MOOC (Massive Online Open Courses) platforms. We discuss how the private provision of MOOCs can be sustained. Using the ... [more ▼]

We use various economic and pedagogical concepts to understand the specificities of MOOC (Massive Online Open Courses) platforms. We discuss how the private provision of MOOCs can be sustained. Using the theory of multisided platforms, we analyze five ways to monetize the MOOC business. We then claim that MOOC platforms can play a key transformative role in the higher education sector by making teaching practices evolve, rather than by replacing incumbent institutions. Finally, we derive a number of directions for public policy [less ▲]

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See detail2D dynamic studies combined with the surface curvature analysis to predict Arias Intensity amplification
Torgoev, Almazbek ULg; Havenith, Hans-Balder ULg

in Journal of Seismology (2016)

A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings ... [more ▼]

A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings of the landslide-prone slopes situated in the Mailuu-Suu River Valley, Southern Kyrgyzstan. The main studied parameter is the Arias Intensity (Ia, m/sec), which is applied in the GIS-based Newmark method to regionally map the seismically-induced landslide susceptibility. This method maps the Ia values via empirical attenuation laws and our studies investigate a potential to include topographic input into them. Numerical studies analyse several signals with varying shape and changing central frequency values. All tests demonstrate that the spectral amplification patterns directly affect the amplification of the Ia values. These results let to link the 2D distribution of the topographically amplified Ia values with the parameter called as smoothed curvature. The amplification values for the low-frequency signals are better correlated with the curvature smoothed over larger spatial extent, while those values for the high-frequency signals are more linked to the curvature with smaller smoothing extent. The best predictions are provided by the curvature smoothed over the extent calculated according to Geli’s law. The sample equations predicting the Ia amplification based on the smoothed curvature are presented for the sinusoid-shape input signals. These laws cannot be directly implemented in the regional Newmark method, as 3D amplification of the Ia values addresses more problem complexities which are not studied here. Nevertheless, our 2D results prepare the theoretical framework which can potentially be applied to the 3D domain and, therefore, represent a robust basis for these future research targets. [less ▲]

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See detailApprendre à faire semblant. A propos de "Furyo" de Nagisa Oshima
Tomasovic, Dick ULg

in Mondes du cinéma (2016), 08

Une analyse des préceptes qui gouvernent la mise en scène du film "Furyo" d’Oshima, en insistant particulièrement sur l'analyse de la bande sonore et la présence à l'écran de David Bowie et Ryuichi ... [more ▼]

Une analyse des préceptes qui gouvernent la mise en scène du film "Furyo" d’Oshima, en insistant particulièrement sur l'analyse de la bande sonore et la présence à l'écran de David Bowie et Ryuichi Sakamoto. [less ▲]

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See detailImpact of three phtalate esters on the sexual reproduction of the Monogont rotifer, Brachionus calyciflorus
Cruciani, Valentina ULg; Iovine, Catherine; Thomé, Jean-Pierre ULg et al

in Ecotoxicology (2016), 25(1), 192-200

Phthalate esters are widespread contaminants that can cause endocrine disruption in vertebrates. Studies showed that molecules with hormonal activities in vertebrates and invertebrates can affect asexual ... [more ▼]

Phthalate esters are widespread contaminants that can cause endocrine disruption in vertebrates. Studies showed that molecules with hormonal activities in vertebrates and invertebrates can affect asexual and sexual reproduction in rotifers. We investigated the impact of di-hexylethyl phthalate (DEHP), di-butyl phthalate (DBP) and butylbenzyl phthalate (BBP), on the asexual and sexual reproduction of the freshwater monogonont rotifer Brachionus calyciflorus in order to determine a potential environmental risk for sexual reproduction. We observed that DEHP has no significant impact on both asexual and sexual reproduction up to 2 mg/L. DBP has a positive effect on asexual reproduction at concentrations from 0.05 to 1mg/L, but depresses it at 2 mg/L. Sexual reproduction is only affected with 2mg/L and the impact observed is negative. BBP displayed a negative impact on both asexual and sexual reproduction at 1 and 2 mg/L. However we showed that the impacts of BBP on fertilization rates observed are due to the decrease in population growth rates at these concentrations and are not due to a direct impact of BBP on the fertilization process. Similar conclusions are likely applicable to the impacts on mixis and production of cysts as well. Our results show that sexual reproduction in B. calyciflorus is not more sensitive than asexual reproduction to any of the substances tested which indicates the mode of action of these molecules is related to general toxicity, not to an interference with potential endocrine regulation of sexual reproduction. Comparison of effect concentrations and surface water contamination by phthalate esters suggests these compounds do not constitute a risk for these environments. [less ▲]

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See detailCompte-rendu de : GÉRARD E., DE RIDDER W., MULLER F., Qui a tué Julien Lahaut ? Les ombres de la Guerre Froide en Belgique, Bruxelles, La Renaissance du Livre, 2015, 352 p.
Genin, Vincent ULg

in Bulletin d'Information de l'Association Belge d'Histoire Contemporaine = Mededelingenblad van de Belgische Vereniging voor Nieuwste Geschiedenis (2016), XXXVII(2015/4), 21-24

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See detailPerformance characteristics of the VIDAS 25-OH Vitamin D total assay - comparison with four immunoassays and two liquid chromatography-tandem mass spectrometry methods in a multicentric study
Moreau, E; Bächer, S; Mery, S et al

in Clinical Chemistry & Laboratory Medicine (2016)

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other ... [more ▼]

Background: The study was conducted to evaluate the analytical and clinical performance of the VIDAS® 25-OH Vitamin D Total assay. The clinical performance of the assay was compared with four other immunoassays against the results of two different liquid chromatography/ mass spectrometry methods (LC-MS/MS) standardized to NIST reference materials. Methods: VIDAS® 25-OH Vitamin D Total assay precision, linearity, detection limits and sample matrix comparison were assessed following CLSI guidelines. For method comparison, a total of 150 serum samples ranging from 7 to 92 ng/mL were analyzed by all the methods. Correlation was studied using Passing-Bablok regression and Bland- Altman analysis. The concordance correlation coefficient (CCC) was calculated to evaluate agreement between immunoassays and the reference LC-MS/MS method. In addition, samples containing endogenous 25(OH)D2 were used to assess each immunoassay’s ability to detect this analyte. Pregnancy and hemodialysis samples were used to the study the effect of vitamin D binding protein (DBP) concentration over VIDAS® assay performance. Results: The VIDAS® 25-OH Vitamin D Total assay showed excellent correlation to the LC-MS/MS results (y = 1.01x+0.22 ng/mL, r = 0.93), as obtained from two different sites and distinct LC-MS/MS methods. The limit of quantification was determined at 8.1 ng/mL. Cross-reactivity for 25(OH)D2 was over 80%. At concentrations of 10.5, 26 and 65.1 ng/mL, within-run CVs were 7.9%, 3.6% and 1.7%, while total CVs (between runs, calibrations, lots and instruments) were 16.0%, 4.5% and 2.8%. The VIDAS® performance was not influenced by altered DBP levels, though under-recovery of 25(OH)D as compared to LC-MS/ MS was observed for hemodialysis samples. Conclusions: The VIDAS® 25-OH Vitamin D Total assay is therefore considered suitable for assessment of vitamin D status in clinical routine. Keywords: assay performance; liquid chromatography/ [less ▲]

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See detailBreakdown of Anderson localization in the transport of Bose-Einstein condensates through one-dimensional disordered potentials
Dujardin, Julien ULg; Engl, Thomas; Schlagheck, Peter ULg

in Physical Review A (2016), 93

We study the transport of an interacting Bose–Einstein condensate through a 1D correlated disorder potential. We use for this purpose the truncated Wigner method, which is, as we show, corresponding to ... [more ▼]

We study the transport of an interacting Bose–Einstein condensate through a 1D correlated disorder potential. We use for this purpose the truncated Wigner method, which is, as we show, corresponding to the diagonal approximation of a semiclassical van Vleck–Gutzwiller representation of this many-body transport process. We also argue that semiclassical corrections beyond this diagonal approximation are vanishing under disorder average, thus confirming the validity of the truncated Wigner method in this context. Numerical calculations show that, while for weak atom-atom interaction strengths Anderson localization is preserved with a slight modification of the localization length, for larger interaction strengths a crossover to a delocalized regime exists due to inelastic scattering. In this case, the transport is fully incoherent. [less ▲]

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See detailLe cas tunisien
Nachi, Mohamed ULg

in Revue Nouvelle (2016), 71(1), 61-68

Mise en exergue de l'importance du rôle du compromis dans la transition démocratique en Tunisie

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See detailAutomatic artifacts and arousals detection in whole-night sleep EEG recordings
Coppieters't Wallant, Dorothe ULg; Muto, Vincenzo ULg; Gaggioni, Giulia ULg et al

in Journal of Neuroscience Methods (2016), 258

In sleep electroencephalographic (EEG) signals, artifacts and arousals marking are usually part of the processing. This visual inspection by a human expert has two main drawbacks: it is very time ... [more ▼]

In sleep electroencephalographic (EEG) signals, artifacts and arousals marking are usually part of the processing. This visual inspection by a human expert has two main drawbacks: it is very time consuming and subjective. To detect artifacts and arousals in a reliable, systematic and reproducible automatic way, we developed an automatic detection based on time and frequency analysis with adapted thresholds derived from data themselves. The automatic detection performance is assessed using 5 statistic parameters, on 60 whole night sleep recordings coming from 35 healthy volunteers (male and female) aged between 19 and 26. The proposed approach proves its robustness against inter- and intra-, subjects and raters’ scorings, variability. The agreement with human raters is rated overall from substantial to excellent and provides a significantly more reliable method than between human raters. Existing methods detect only specific artifacts or only arousals, and/or these methods are validated on short episodes of sleep recordings, making it difficult to compare with our whole night results. The method works on a whole night recording and is fully automatic, reproducible, and reliable. Furthermore the implementation of the method will be made available online as open source code. [less ▲]

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See detailACCOUCHEMENT PAR VOIE BASSE SUR UTÉRUS BI-CICATRICIEL : A PROPOS DE TROIS CAS
Christiane, Yolande; Emonts, Patrick ULg

in Revue Médicale de Liège (2016), 71(9), 388-393

Despite awareness of obstetricians to the constant increase in the number of caesarean sections in recent years, certain dogmas concerning uterine scar still persist in our practices and influence ... [more ▼]

Despite awareness of obstetricians to the constant increase in the number of caesarean sections in recent years, certain dogmas concerning uterine scar still persist in our practices and influence clinical decisions. Fear of a uterine scar rupture, a major obstetric complication, is always in mind. As for bi-uterine scar, it was considered, until recently in Belgium, as a total and definitive indication against an attempted vaginal delivery. However, several previous clinical studies clearly showed that, under certain conditions, vaginal birth after two caesarean was usually successful with very good results in terms of maternal and fetal morbidities. Even if such a clinical situation is not common, this article would sensitize obstetricians to the lack of objective clinical arguments to reject a vaginal delivery in a patient having a previous history of two caesarean sections. Such a patient must be motivated and coming within a specific framework. Moreover, this type of delivery should receive optimal monitoring. [less ▲]

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See detailQuasi-periodic injections of relativistic electrons in Saturn's outer magnetosphere
Roussos, E.; Krupp, N.; Mitchell, D. G. et al

in Icarus (2016), 263

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See detailRéparation des ouvrages en béton armé - Partie 1 : Pathologies et diagnostic
Courard, Luc ULg; Bissonnette, Benoît

in Techniques de l'Ingénieur. Analyse Chimique et Caractérisation (2016)

Repair of concrete not only requires knowledge of the support to repair, the repair materials and the environmental conditions in which they will be implemented, but also an understanding of the ... [more ▼]

Repair of concrete not only requires knowledge of the support to repair, the repair materials and the environmental conditions in which they will be implemented, but also an understanding of the mechanisms underlying adhesion. Dimensional, electrochemical, chemical and porosity (permeability) compatibilities are the key to the success and durability of the repair. In a first part, an analysis of the patrimonial heritage at stake and the possible intervention strategies is proposed. The emphasis is put here on the study of the effects and causes of deterioration affecting reinforced concrete structures: cracking, spalling and disintegration are the main types surface defects observed, most often in connection with corrosion of the underlying steel reinforcement. A proper diagnosis will allow selecting the most suitable repair techniques and materials (Part 2). [less ▲]

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See detailDoes the Arctic charr Salvelinus alpinus produce sounds in a captive setting?
Bolgan, Marta ULg; O'Brien, Joanne; Rountree, R. A. et al

in Journal of Fish Biology (2016), 89(3), 1857-1865

Arctic charr Salvelinus alpinus did not appear to invest in acoustic communication during courtship and agonistic interactions in captivity. Salvelinus alpinus did, however, produce four different types ... [more ▼]

Arctic charr Salvelinus alpinus did not appear to invest in acoustic communication during courtship and agonistic interactions in captivity. Salvelinus alpinus did, however, produce four different types of sounds which were found to be associated with three different types of air exchange behaviours which probably have a swimbladder regulation function. Since air passage sounds appear to be common among Salmonidae, it is suggested that the potential of passive acoustics techniques for behavioural and ecological monitoring should be further investigated in future field and laboratory investigations. © 2016 The Fisheries Society of the British Isles [less ▲]

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See detailStakeholders’ perceptions, attitudes and practices towards risk prevention in the food chain
Lupo, C; Wilmart, O; Van Huffel, X et al

in Food Control (2016), 66

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See detailCompte rendu de Christophe CHANDEZON, Julien DU BOUCHET (éds.), Artémidore de Daldis et l’interprétation des rêves. Quatorze études
Berg, Tatiana ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (2016), 85

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See detailEACVI appropriateness criteria for the use of cardiovascular imaging in heart failure derived from European National Imaging Societies voting.
Garbi, Madalina; Edvardsen, Thor; Bax, Jeroen et al

in European heart journal cardiovascular Imaging (2016)

This paper presents the first European appropriateness criteria for the use of cardiovascular imaging in heart failure, derived from voting of the European National Imaging Societies representatives. The ... [more ▼]

This paper presents the first European appropriateness criteria for the use of cardiovascular imaging in heart failure, derived from voting of the European National Imaging Societies representatives. The paper describes the development process and discusses the results. [less ▲]

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See detailQuadratization of symmetric pseudo-Boolean functions
Anthony, Martin; Boros, Endre; Crama, Yves ULg et al

in Discrete Applied Mathematics (2016), 203

A pseudo-Boolean function is a real-valued function $f(x)=f(x_1,x_2,\ldots,x_n)$ of $n$ binary variables; that is, a mapping from $\{0,1\}^n$ to ${\bbr}$. For a pseudo-Boolean function $f(x)$ on $\{0,1 ... [more ▼]

A pseudo-Boolean function is a real-valued function $f(x)=f(x_1,x_2,\ldots,x_n)$ of $n$ binary variables; that is, a mapping from $\{0,1\}^n$ to ${\bbr}$. For a pseudo-Boolean function $f(x)$ on $\{0,1\}^n$, we say that $g(x,y)$ is a quadratization of $f$ if $g(x,y)$ is a Quadratic polynomial depending on $x$ and on $m$ auxiliary binary variables $y_1,y_2,\ldots,y_m$ such that $f(x)= \min \{ g(x,y) : y \in \{0,1\}^m \} $ for all $x \in \{0,1\}^n$. By means of quadratizations, minimization of $f$ is reduced to minimization (over its extended set of variables) of the quadratic function $g(x,y)$. This is of some practical interest because minimization of quadratic functions has been thoroughly studied for the last few decades, and much progress has been made in solving such problems exactly or heuristically. A related paper initiated a systematic study of the minimum number of auxiliary $y$-variables required in a quadratization of an arbitrary function $f$ (a natural question, since the complexity of minimizing the quadratic function $g(x,y)$ depends, among other factors, on the number of binary variables). In this paper, we determine more precisely the number of auxiliary variables required by quadratizations of \emph{symmetric} pseudo-Boolean functions $f(x)$, those functions whose value depends only on the Hamming weight of the input $x$ (the number of variables equal to 1). [less ▲]

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See detailA systematic review of geological evidence for Holocene earthquakes and tsunamis along the Nankai-Suruga Trough, Japan
Garrett, Ed; Fujiwara, Osamu; Garrett, Philip et al

in Earth-Science Reviews (2016)

The Nankai-Suruga Trough, the subduction zone that lies immediately south of Japan’s densely populated southern coastline, generates devastating great earthquakes (magnitude > 8) characterised by intense ... [more ▼]

The Nankai-Suruga Trough, the subduction zone that lies immediately south of Japan’s densely populated southern coastline, generates devastating great earthquakes (magnitude > 8) characterised by intense shaking, crustal deformation and tsunami generation. Forecasting the hazards associated with future earthquakes along this >700 km long fault requires a comprehensive understanding of past fault behaviour. While the region benefits from a long and detailed historical record, palaeoseismology has the potential to provide a longer-term perspective and additional crucial insights. In this paper, we summarise the current state of knowledge regarding geological evidence for past earthquakes and tsunamis along the Nankai-Suruga Trough. Incorporating literature originally published in both Japanese and English and enhancing available results with new age modelling approaches, we summarise and critically evaluate evidence from a wide variety of sources. Palaeoseismic evidence includes uplifted marine terraces and biota, marine and lacustrine turbidites, liquefaction features, subsided marshes and tsunami deposits in coastal lakes and lowlands. While 75 publications describe proposed evidence from more than 70 sites, only a limited number provide compelling, well-dated evidence. The best available records enable us to map the most likely rupture zones of twelve earthquakes occurring during the historical period. This spatiotemporal compilation suggests the AD 1707 earthquake ruptured almost the full length of the subduction zone and that earthquakes in AD 1361 and 684 may have been predecessors of similar magnitude. Intervening earthquakes were of lesser magnitude, highlighting the variability in rupture mode that characterises the Nankai-Suruga Trough. Recurrence intervals for ruptures of the same seismic segment range from less than 100 to more than 450 years during the historical period. Over longer timescales, palaeoseismic evidence suggests intervals between earthquakes ranging from 100 to 700 years, however these figures reflect a range of thresholds controlling the of creation and preservation of evidence at any given site as well as genuine earthquake recurrence intervals. At present, there is no geological data that suggest the occurrence of a larger magnitude earthquake than that experienced in AD 1707, however few studies have sought to establish the relative magnitudes of different earthquake and tsunami events along the Nankai-Suruga Trough. Alongside the lack of research designed to quantify the maximum magnitude of past earthquakes, we emphasise issues over alternative hypotheses for proposed palaeoseismic evidence, the paucity of robust chronological frameworks and insufficient appreciation of changing thresholds of evidence creation and preservation over time as key issues that must be addressed by future research. [less ▲]

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See detailIdentification of specific bovine blood biomarkers with a non-targeted approach using HPLC ESI tandem mass spectrometry
Lecrenier, Marie-Caroline ULg; Marbaix, Hélène; Dieu, Marc et al

in Food Chemistry (2016), 213

Animal by-products are valuable protein sources in animal nutrition. Among them are blood products and blood meal, which are used as high-quality material for their beneficial effects on growth and health ... [more ▼]

Animal by-products are valuable protein sources in animal nutrition. Among them are blood products and blood meal, which are used as high-quality material for their beneficial effects on growth and health. Within the framework of the feed ban relaxation, the development of complementary methods in order to refine the identification of processed animal proteins remains challenging. The aim of this study was to identify specific biomarkers that would allow the detection of bovine blood products and processed animal proteins using tandem mass spectrometry. Seventeen biomarkers were identified: nine peptides for bovine plasma powder; seven peptides for bovine haemoglobin powder, including six peptides for bovine blood meal; and one peptide for porcine blood. They were not detected in several commercial compound feed or feed materials, such as blood by-products of other animal origins, milk-derived products and fish meal. These biomarkers could be used for developing a species-specific and blood-specific detection method. [less ▲]

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See detailCombinaison fixe atorvastatine-ezetimibe (Atozet(R)).
Scheen, André ULg

in Revue medicale de Liege (2016), 71(1), 47-52

Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of ... [more ▼]

Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of cholesterol synthesis and a selective inhibitor of intestinal absorption results in a complementary and synergistic LDL-lowering activity. Besides a first fixed combination ezetimibe-simvastatin (Inegy(R)), a new fixed combination is presented, Atozet(R) that combines atorvastatin and ezetimibe. Because atorvastatin is more potent than simvastatin, this novel fixed combination should facilitate reaching therapeutic goals in terms of LDL cholesterol amongst patients with severe hypercholesterolaemia and/or at high or very high cardiovascular risk. [less ▲]

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See detailPalindromic sequences generated from marked morphisms
Labbé, Sébastien ULg; Pelantova, Edita

in European Journal of Combinatorics (2016), 51

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See detailA Statistically adaptive sampling policy to the Hotelling's T2 Control Chart: Markov Chain Approach
Seif, A.; Faraz, Alireza ULg; Heuchenne, Cédric ULg et al

in Communications in Statistics : Theory & Methods (2016)

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