References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailVers un modèle d’apprentissage réflexif. Recueil de traces d’apprentissage formulées dans les log books des stagiaires en médecine
Vierset, Viviane ULg

in Approches Inductives : Travail Intellectuel et Construction des Connaissances (2016)

Detailed reference viewed: 18 (3 ULg)
Full Text
Peer Reviewed
See detailDSIMA: A testbed for the quantitative analysis of interaction models within distribution networks
Mathieu, Sébastien ULg; Louveaux, Quentin ULg; Ernst, Damien ULg et al

in Sustainable Energy, Grids and Networks (2016), 5

This article proposes an open-source testbed to simulate interaction models governing the exchange of flexibility services located within a distribution network. The testbed is an agent-based system in ... [more ▼]

This article proposes an open-source testbed to simulate interaction models governing the exchange of flexibility services located within a distribution network. The testbed is an agent-based system in which the distribution system operator, the transmission system operator, producers and retailers make their decisions based on mixed-integer linear programs. This testbed helps to highlight the characteristics of an interaction model, the benefits for the agents and eases the detection of unwanted or abusive behaviors which decreases the welfare. The testbed is implemented in Python and the optimization problems are encoded in the modeling language ZIMPL. A web interface is coupled with an instance generator using macroscopic parameters of the system such as the total power production. This testbed is, therefore, well suited to test the implemented interaction models on various scenarios and to extend the implementation to other models. Five interaction models developed with industrial partners are simulated over a year on a 75-bus test system. Simulations show that interaction models relying on active network management, as they have been developed, lead to substantial welfare even though they suffer from a lack of coordination between the DSO and the TSO. A conservative interaction model restricting grid users to an access range that is computed ahead of time to prevent any congestion, avoids shedding distributed generation but considerably restrains the amount of distributed production. [less ▲]

Detailed reference viewed: 418 (35 ULg)
Full Text
Peer Reviewed
See detailClassification of riparian forest species and health condition using multi-temporal and hyperspatial imagery from unmanned aerial system
Michez, Adrien ULg; Piégay, Hervé; Lisein, Jonathan ULg et al

in Environmental Monitoring and Assessment (2016), 188(3),

Riparian forests are critically endangered many anthropogenic pressures and natural hazards. The importance of riparian zones has been acknowledged by European Directives, involving multi-scale monitoring ... [more ▼]

Riparian forests are critically endangered many anthropogenic pressures and natural hazards. The importance of riparian zones has been acknowledged by European Directives, involving multi-scale monitoring. The use of this very high resolution and hyperspatial imagery in a multi-temporal approach is an emerging topic. The trend is reinforced by the recent and rapid growth of the use of the unmanned aerial system (UAS), which has prompted the development of innovative methodology. Our study proposes a methodological framework to explore how a set of multi-temporal images acquired during a vegetative period can differentiate some of the deciduous riparian forest species and their health conditions. More specifically, the developed approach intends to identify, through a process of variable selection, which variables derived from UAS imagery and which scale of image analysis are the most relevant to our objectives. The methodological framework is applied to two study sites to describe the riparian forest through two fundamental characteristics: the species composition and the health condition. These characteristics were selected not only because of their use as proxies for the riparian zone ecological integrity but also because of their use for river management. The comparison of various scales of image analysis identified the smallest OBIA objects (ca. 1 m²) as the most relevant scale. Variables derived from spectral information (bands ratio's) were identified as the most appropriate, followed by variables related to the vertical structure of the forest. Classification results show good overall accuracies for the species composition of the riparian forest (five classes, 79.5 and 84.1 % for Site 1 and Site 2). The classification scenario regarding the health condition of the black alders of the Site 1 performed the best (90.6 %). The quality of the classification models developed with a UAS-based, cost-effective, and semi-automatic approach competes successfully with those developed using more expensive imagery, such as multispectral and hyperspectral airborne imagery. The high overall accuracy results obtained by the classification of the diseased alders open the door to applications dedicated to monitoring of the health conditions of riparian forest. Our methodological framework will allow UAS users to manage large imagery metrics datasets derived from those dense time series. [less ▲]

Detailed reference viewed: 35 (10 ULg)
Full Text
Peer Reviewed
See detailLes droits fondamentaux, au coeur de la pluralité des sources et de la pluralité des juges: vers une "dématérialisation" des droits fondamentaux?
Rosoux, Géraldine ULg

in Revue de la Faculté de Droit de l'Université de Liège (2016)

L'article contient un résumé de la thèse de doctorat de l'auteur, publiée chez Bruylant en 2015.

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailDiscretization of the divergence formulation of the bed slope term in the shallow-water equations and consequences in terms of energy balance
Bruwier, Martin ULg; Archambeau, Pierre ULg; Erpicum, Sébastien ULg et al

in Applied Mathematical Modelling (2016)

In this research, the influence on energy balance of the discretization scheme of the divergence formulation of the bed slope term in the shallow-water equations is analysed theoretically (for a single ... [more ▼]

In this research, the influence on energy balance of the discretization scheme of the divergence formulation of the bed slope term in the shallow-water equations is analysed theoretically (for a single topographic step) and based on two numerical tests. Different values of the main parameter controlling the discretization scheme of the divergence formulation are analysed to identify the formulation which minimizes the energy variation resulting from the discretization. For a wide range of ambient Froude numbers and relative step heights, the theoretical value of the control parameter minimizing the energy variation falls within a very narrow range, which can reasonably be approximated by a single “optimal” value. This is a result of high practical relevance for the design of accurate numerical schemes, as confirmed by the results of the numerical tests. [less ▲]

Detailed reference viewed: 33 (11 ULg)
Full Text
Peer Reviewed
See detailOrigin of dc voltage in type II superconducting flux pumps: field, field rate of change, and current density dependence of resistivity
Geng, J.; Matsuda, K.; Fu, L. et al

in Journal of Physics : D Applied Physics (2016), 49(11), 1101

Superconducting flux pumps are the kind of devices which can generate direct current into superconducting circuit using external magnetic field. The key point is how to induce a dc voltage across the ... [more ▼]

Superconducting flux pumps are the kind of devices which can generate direct current into superconducting circuit using external magnetic field. The key point is how to induce a dc voltage across the superconducting load by ac fields. Giaever (1966 IEEE Spectr . 3 [http://dx.doi.org/10.1109/MSPEC.1966.5217702] 117 ) pointed out flux motion in superconductors will induce a dc voltage, and demonstrated a rectifier model which depended on breaking superconductivity. van de Klundert et al (1981 Cryogenics 21 [http://dx.doi.org/10.1016/0011-2275(81)90195-8] 195, 267 ) in their review(s) described various configurations for flux pumps all of which relied on inducing the normal state in at least part of the superconductor. In this letter, following their work, we reveal that a variation in the resistivity of type II superconductors is sufficient to induce a dc voltage in flux pumps and it is not necessary to break superconductivity. This variation in resistivity is due to the fact that flux flow is influenced by current density, field intensity, and field rate of change. We propose a general circuit analogy for travelling wave flux pumps, and provide a mathematical analysis to explain the dc voltage. Several existing superconducting flux pumps which rely on the use of a travelling magnetic wave can be explained using the analysis enclosed. This work can also throw light on the design and optimization of flux pumps. [less ▲]

Detailed reference viewed: 14 (5 ULg)
Full Text
Peer Reviewed
See detailVirtual Issue celebrating the 100th volume of the Journal of Animal Physiology and Animal Nutrition
Fascetti, A. J.; Everaert, Nadia ULg

in Journal of Animal Physiology and Animal Nutrition (2016), 100(1), 1-2

[No abstract available]

Detailed reference viewed: 8 (2 ULg)
Full Text
Peer Reviewed
See detailLinseed oil presents different patterns of oxidation in real-time and accelerated aging assays
Douny, Caroline ULg; Razanakolona, Rina; Ribonnet, Laurence et al

in Food Chemistry (2016), 208

This study aimed at verifying if the hypothesis that one day at 60 °C is equivalent to one month at 20 °C could be confirmed during linseed oil aging for 6 months at 20 °C and 6 days at 60 °C using the ... [more ▼]

This study aimed at verifying if the hypothesis that one day at 60 °C is equivalent to one month at 20 °C could be confirmed during linseed oil aging for 6 months at 20 °C and 6 days at 60 °C using the “Schaal oven stability test”. Tests were conducted with linseed oil supplemented or not with myricetin or butyl-hydroxytoluene as antioxidants. Oxidation was evaluated with the peroxide and p-anisidine values, as well as the content in conjugated dienes and aldehydes. All four indicators of oxidation showed very different kinetic behaviors at 20 and 60 °C. The hypothesis is thus not verified for linseed oil, supplemented or not with antioxidant. In the control oil, the conjugated dienes and the peroxide value observed were respectively of 41.8 ± 0.8 Absorbance Unit (AU)/g oil and 254.3 ± 5.8 meq. O2/kg oil after 6 months at 20 °C. These values were of 18.2 ± 1.3 AU/g oil and 65.2 ± 20.3 meq. O2/kg after 6 days at 60 °C. [less ▲]

Detailed reference viewed: 33 (6 ULg)
Full Text
Peer Reviewed
See detailFDG PET/CT texture analysis for predicting the outcome of lung cancer treated by stereotactic body radiation therapy.
LOVINFOSSE, Pierre ULg; Janvary, Zsolt Levente; COUCKE, Philippe ULg et al

in European journal of nuclear medicine and molecular imaging (2016)

INTRODUCTION: With 18F-FDG PET/CT, tumor uptake intensity and heterogeneity have been associated with outcome in several cancers. This study aimed at investigating whether 18F-FDG uptake intensity, volume ... [more ▼]

INTRODUCTION: With 18F-FDG PET/CT, tumor uptake intensity and heterogeneity have been associated with outcome in several cancers. This study aimed at investigating whether 18F-FDG uptake intensity, volume or heterogeneity could predict the outcome in patients with non-small cell lung cancers (NSCLC) treated by stereotactic body radiation therapy (SBRT). METHODS: Sixty-three patients with NSCLC treated by SBRT underwent a 18F-FDG PET/CT before treatment. Maximum and mean standard uptake value (SUVmax and SUVmean), metabolic tumoral volume (MTV), total lesion glycolysis (TLG), as well as 13 global, local and regional textural features were analysed. The predictive value of these parameters, along with clinical features, was assessed using univariate and multivariate analysis for overall survival (OS), disease-specific survival (DSS) and disease-free survival (DFS). Cutoff values were obtained using logistic regression analysis, and survivals were compared using Kaplan-Meier analysis. RESULTS: The median follow-up period was 27.1 months for the entire cohort and 32.1 months for the surviving patients. At the end of the study, 25 patients had local and/or distant recurrence including 12 who died because of the cancer progression. None of the clinical variables was predictive of the outcome, except age, which was associated with DFS (HR 1.1, P = 0.002). None of the 18F-FDG PET/CT or clinical parameters, except gender, were associated with OS. The univariate analysis showed that only dissimilarity (D) was associated with DSS (HR = 0.822, P = 0.037), and that several metabolic measurements were associated with DFS. In multivariate analysis, only dissimilarity was significantly associated with DSS (HR = 0.822, P = 0.037) and with DFS (HR = 0.834, P < 0.01). CONCLUSION: The textural feature dissimilarity measured on the baseline 18F-FDG PET/CT appears to be a strong independent predictor of the outcome in patients with NSCLC treated by SBRT. This may help selecting patients who may benefit from closer monitoring and therapeutic optimization. [less ▲]

Detailed reference viewed: 37 (5 ULg)
Full Text
Peer Reviewed
See detailPhenolic profile, antibacterial and cytotoxic properties of second grade date extract from Tunisian cultivars (Phoenix dactylifera L.)
Kchaou, Wissal; Abbès, Fatma; Ben Mansour, Riadh et al

in Food Chemistry (2016), (194), 1048-1055

The present study aimed to investigate the phenolic profile of second grade date extracts and evaluate their antimicrobial and cytotoxic activities with regard to some pathogenic microorganisms. Phenolic ... [more ▼]

The present study aimed to investigate the phenolic profile of second grade date extracts and evaluate their antimicrobial and cytotoxic activities with regard to some pathogenic microorganisms. Phenolic content was analyzed by HPLC. Antimicrobial activity was evaluated by the agar disk diffusion method, and in vitro cytotoxic activity was examined by cell proliferation assay. The results revealed that second grade dates presented three benzoic acids, five cinnamic acids and two flavonoids, with the predominance of q-coumaric acid (1998.80 lg/100 g). The antimicrobial activities showed that the date extracts were active against Gram (+) and Gram (-) bacteria, showing marked activity against Escherichia coli with an inhibition zone of 25 mm. Cytotoxicity assays showed that the date extracts were able to inhibit the proliferation of HeLa cell lines. The results confirmed that the date extracts were rich in biologically active compounds that are highly valued in the functional food and nutraceutical industries. [less ▲]

Detailed reference viewed: 19 (0 ULg)
Full Text
Peer Reviewed
See detailForeign Language Teachers’ Assessment Practices in French-Speaking Belgium’s Upper Secondary Schools: A Case Study
Noiroux, Kevin ULg

in The International Journal of Pedagogy and Curriculum (2016), 23(2),

Foreign language classroom assessment practices are a mystery, at least in Belgium. The present case study aims at shedding light on Belgian foreign languages teachers’ assessment practices in secondary ... [more ▼]

Foreign language classroom assessment practices are a mystery, at least in Belgium. The present case study aims at shedding light on Belgian foreign languages teachers’ assessment practices in secondary education. I interviewed seven teachers to know what they assessed and how often they assessed it. I also analyzed the legal provisions that teachers have to respect when they assess. The results show that teachers assess four communicative skills—listening, reading, writing, and speaking—as legally required, but also reveal that they frequently assess vocabulary and grammar, sometimes in ways that are not permitted. Furthermore, they spend a considerable amount of time assessing those skills without even being aware of it. Since these assessments only aim at verifying that the students master the skills, it may be worth investigating whether some assessments are not redundant so as to devote that time to a more productive task. [less ▲]

Detailed reference viewed: 16 (3 ULg)
Full Text
Peer Reviewed
See detailFluorodeoxyglucose F Positron Emission Tomography Coupled With Computed Tomography in Suspected Acute Renal Allograft Rejection.
Lovinfosse, P.; Weekers, L.; Bonvoisin, C. et al

in American Journal of Transplantation (2016)

Management of kidney transplant recipients (KTRs) with suspected acute rejection (AR) ultimately relies on kidney biopsy; however, noninvasive tests predicting nonrejection would help avoid unnecessary ... [more ▼]

Management of kidney transplant recipients (KTRs) with suspected acute rejection (AR) ultimately relies on kidney biopsy; however, noninvasive tests predicting nonrejection would help avoid unnecessary biopsy. AR involves recruitment of leukocytes avid for fluorodeoxyglucose F18 (18 F-FDG), thus 18 F-FDG positron emission tomography (PET) coupled with computed tomography (CT) may noninvasively distinguish nonrejection from AR. From January 2013 to February 2015, we prospectively performed 32 18 F-FDG PET/CT scans in 31 adult KTRs with suspected AR who underwent transplant biopsy. Biopsies were categorized into four groups: normal (n = 8), borderline (n = 10), AR (n = 8), or other (n = 6, including 3 with polyoma BK nephropathy). Estimated GFR was comparable in all groups. PET/CT was performed 201 +/- 18 minutes after administration of 3.2 +/- 0.2 MBq/kg of 18 F-FDG, before any immunosuppression change. Mean standard uptake values (SUVs) of both upper and lower renal poles were measured. Mean SUVs reached 1.5 +/- 0.2, 1.6 +/- 0.3, 2.9 +/- 0.8, and 2.2 +/- 1.2 for the normal, borderline, AR, and other groups, respectively. One-way analysis of variance demonstrated a significant difference of mean SUVs among groups. A positive correlation between mean SUV and acute composite Banff score was found, with r2 = 0.49. The area under the receiver operating characteristic curve was 0.93, with 100% sensitivity and 50% specificity using a mean SUV threshold of 1.6. In conclusion, 18 F-FDG PET/CT may help noninvasively prevent avoidable transplant biopsies in KTRs with suspected AR. [less ▲]

Detailed reference viewed: 43 (14 ULg)
Full Text
Peer Reviewed
See detailInvestigation of the genotoxicity of substances migrating from polycarbonate replacement baby bottles to identify chemicals of high concern.
Mertens; Simon, Coraline ULg; Van Bossuyt et al

in Food & Chemical Toxicology (2016), 89

Detailed reference viewed: 10 (2 ULg)
Full Text
Peer Reviewed
See detailLoadbearing capacity criteria in fire resistance testing
Dumont, Fabien ULg; Wellens, Eric ULg; Gernay, Thomas ULg et al

in Materials and Structures (2016)

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the ... [more ▼]

The European system for fire testing and classification of loadbearing building elements lacks consistency because the two standards that have to be applied prescribe different criteria for assessing the loadbearing performance. This article analyzes the implications of the present conflict between the standard for testing and the standard for classification. The prescribed criteria for loadbearing performance are related to the exceedance of deflection and rate of deflection thresholds. A database of 46 fire resistance tests performed at the University of Liege is collected that contains the time at which these thresholds are reached in fire tests with different typologies of elements (walls, floors, columns and beams). Then, the loadbearing performance (and hence the fire resistance rating) can be derived according to the two standards. The evolutions of deflection and rate of deflection during the tests are also analyzed to gain a better understanding of the adequacy of the standards. The selection of one or the other standard affects the time at which “failure” is deemed to occur in fire tests. Statistically speaking, the difference in terms of failure time that results from using one or the other standard has a 25% probability to exceed 10%. In certain cases, this results in a difference in fire resistance rating; this was observed for 3 of the analyzed tests. The apparent contradiction in two codes in application has potential practical implications and therefore needs to be solved. The article suggests some guidelines for defining homogenized and consistent criteria. [less ▲]

Detailed reference viewed: 26 (10 ULg)
Full Text
Peer Reviewed
See detailL'impôt sur les revenus des salariés et l'extranéité (2e partie)
Docclo, Caroline ULg

in Journal des Tribunaux du Travail (2016)

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailTransient performance evaluation of waste heat recovery Rankine cycle based system for heavy duty trucks
Grelet, Vincent; Reiche, Thomas; Lemort, Vincent ULg et al

in Applied Energy (2016)

The study presented in this paper aims to evaluate the transient performance of a waste heat recovery Rankine cycle based system for a heavy duty truck and compare it to steady state evaluation. Assuming ... [more ▼]

The study presented in this paper aims to evaluate the transient performance of a waste heat recovery Rankine cycle based system for a heavy duty truck and compare it to steady state evaluation. Assuming some conditions to hold, simple thermodynamic simulations are carried out for the comparison of several fluids. Then a detailed rst principle based model is also presented. Last part is focused on the Rankine cycle arrangement choice by means of model based evaluation of fuel economy for each concept where the fuels savings are computed using two methodologies. Fluid choice and concept optimization are conducted taking into account integration constraints (heat rejection, packaging . . . ). This paper shows the importance of the modeling phase when designing WHRS and yields a better understanding when it comes to a vehicle integration of a Rankine cycle in a truck. [less ▲]

Detailed reference viewed: 74 (6 ULg)
Full Text
Peer Reviewed
See detailMetabolic profile of mixed culture acidogenic fermentation of lignocellulosic residues and the effect of upstream substrate fractionation by steam explosion
Perimenis, Anastasios; van Aarle, Ingrid; Nicolay, Thomas et al

in Biomass Conversion and Biorefinery (2016), 6

Lignocellulosic biomass residues have attracted attention for the sustainable production of molecules for material and energetic use through biochemical conversion. Their recalcitrant structure prevents a ... [more ▼]

Lignocellulosic biomass residues have attracted attention for the sustainable production of molecules for material and energetic use through biochemical conversion. Their recalcitrant structure prevents a broader use and asks for the development of sustainable techniques that can efficiently separate, recover and valorize the constituting components. In a cascading concept, residual streams of such processes can be further exploited in an attempt to valorize the largest possible fraction of the initial material. Three lignocellulosic substrates, namely dried sugar beet pulp, wheat bran and miscanthus straw, were upstream fractionated by steam explosion to extract the hemicellulose fraction. This study evaluated the valorization of the residual solid fraction through mixed acidogenic fermentation for the production of volatile fatty acids (VFA) as platform chemicals. Batch experiments have been conducted for the reference material (non-treated) and the solid fraction remaining after steam explosion, with and without the addition of an external mixed inoculum. Steam explosion residues contained less hemicellulose than the initial materials. The difference in the fermentation profile between steam explosion residues and non-treated substrates is dependent on the substrate. Maximum total VFA (tVFA) concentration was 18.8 gCOD/kgmixed_liquor, and maximum yield of chemical oxygen demand (COD) conversion into tVFAwas 33 % for the case of non-treated inoculated beet pulp. [less ▲]

Detailed reference viewed: 40 (2 ULg)
Full Text
Peer Reviewed
See detailDe la grammaire pure logique à la grammaire philosophique. La grammaire des concepts chez Wittgenstein
Gauvry, Charlotte ULg

in Bulletin d'Analyse Phénoménologique (2016)

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailMonitoring the laccase reaction of vanillin and poplar hydrolysate
Sòti, Valentin; Jacquet, Nicolas ULg; Apers, Sandra et al

in Journal of Chemical Technology & Biotechnology (2016), 91(6), 1914-1922

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during ... [more ▼]

BACKGROUND: Laccase is an intensively researched enzyme for industrial use. Except for decolorisation measurements, HPLC analysis is the conventional method for monitoring the phenolic removal during laccase enzyme reaction. This paper reports an investigation of the continuous UV absorbance follow-up of the laccase reaction with steam pretreated poplar hydrolysate. RESULTS: Vanillin was used as a model substrate and lignocellulose xylose rich fraction (XRF) as a biologically complex substrate for laccase detoxification. The reaction was followed by HPLC-UV as well as by UV spectrometric measurements. Results suggest that the reaction can be successfully monitored by measuring the change of UV absorbance at 280 nm, without previous compound separation. In case of XRF experiments the spectrophotometric follow-up is especially useful, as HPLC analysis takes a long time and provides less information than in case of single substrates. The method seems to be suitable for optimization and process control. CONCLUSION: The obtained results can help to construct a fast, easy and straightforward monitoring system for laccase-phenolic substrate reactions. [less ▲]

Detailed reference viewed: 47 (20 ULg)
Full Text
Peer Reviewed
See detailBarley (Hordeum distichon L.) roots synthesise volatile aldehydes with a strong age-dependent pattern and release (E)- non-2-enal and (E,Z)-nona-2,6-dienal after mechanical injury
Delory, Benjamin M.; Delaplace, Pierre ULg; du Jardin, Patrick ULg et al

in Plant Physiology and Biochemistry (2016), 104

In the context of chemical ecology, the analysis of the temporal production pattern of volatile organic compounds (VOCs) in root tissues and the emission rate measurement of root-emitted VOCs are of major ... [more ▼]

In the context of chemical ecology, the analysis of the temporal production pattern of volatile organic compounds (VOCs) in root tissues and the emission rate measurement of root-emitted VOCs are of major importance for setting up experiments to study the implication of these compounds in biotic interactions. Such analyses, however, remain challenging because of the belowground location of plant root systems. In this context, this study describes the evolution of the root VOC production pattern of barley (Hordeum distichon L.) at five developmental stages from germination to the end of tillering and evaluates the emission of the identified VOCs in an artificial soil. VOCs produced by crushed root tissues and released by unexcavated root systems were analysed using dynamic sampling devices coupled to a gas chromatography-mass spectrometry methodology (synchronous SCAN/SIM). The results showed that, at each analysed developmental stage, crushed barley roots produced mainly four volatile aldehydes: hexanal; (E)-hex-2-enal; (E)-non-2-enal; and (E,Z)-nona-2,6-dienal. Higher total and individual VOC concentrations were measured in 3-day-old seminal roots compared with older phenological stages. For each developmental stage, the lipoxygenase (LOX) activity was greater for linoleic acid than α-linolenic acid and the greatest LOX activities using linoleic and α- linolenic acids as substrates were measured in 7- and 3-day-old roots, respectively. The analysis of VOCs released by barley roots into the soil showed that (E)-non-2- enal and (E,Z)-nona-2,6-dienal were the only VOCs emitted in quantifiable amounts by mechanically injured roots. [less ▲]

Detailed reference viewed: 22 (9 ULg)
Full Text
Peer Reviewed
See detailStudying Self-Awareness in Children: Validation of the Questionnaire of Executive Functioning (QEF)
Geurten, Marie ULg; Catale, Corinne ULg; Geurten, Claire ULg et al

in Clinical Neuropsychologist (The) (2016)

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of ... [more ▼]

Objective: People with accurate representations of their own cognitive functioning (i.e., cognitive self-awareness) tend to use appropriate strategies to regulate their behavior. Due to the lack of appropriate instruments, few studies have examined the development of this ability among children. Method: This study tested the measurement properties of the self-rating and other-rating forms of the Questionnaire of Executive Functioning (QEF), designed to tap children’s knowledge of their executive functioning. Specifically, the construct, convergent, and discriminant validities were investigated and a self-other discrepancy score was computed to assess children’s executive self-awareness. Participants were 317 children aged 7 to 14 years old. Results: Confirmatory factor analyses carried out on the QEF confirmed the eight-factor structure of both versions. There were significant correlations between the QEF and the parent versions of the Behavior Rating Inventory of Executive Function, the Dysexecutive Questionnaire for Children, and the Childhood Executive Functioning Inventory. Both forms of the QEF were able to distinguish between children who had sustained a traumatic brain injury (TBI) and control participants. A statistical difference was observed between the TBI and control groups on this score, suggesting that TBI may trigger self-awareness impairments in children. Conclusion: The good psychometric properties of the two forms of the QEF were established. Furthermore, results of the analyses carried out on the different discrepancy scores seem to indicate that the QEF could help clinicians to detect patients with self-awareness deficits. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailImprovement of malignant pleural mesothelioma immunotherapy by epigenetic modulators
Hamaïdia, Malik ULg; Staumont, Bernard ULg; DUYSINX, Bernard ULg et al

in Current Topics in Medicinal Chemistry (2016), 16

In the absence of a satisfactory treatment of malignant pleural mesothelioma (MPM), novel therapeutic strategies are urgently needed. Among these, immunotherapy offers a series of advantages such as tumor ... [more ▼]

In the absence of a satisfactory treatment of malignant pleural mesothelioma (MPM), novel therapeutic strategies are urgently needed. Among these, immunotherapy offers a series of advantages such as tumor specificity and good tolerability. Unfortunately, MPM immunotherapy is frequently limited by incomplete cell differentiation or feedback loop regulatory mechanisms. In this review, we describe different components of the innate immune system and discuss strategies to improve MPM immunotherapy by using epigenetic modulators. [less ▲]

Detailed reference viewed: 68 (19 ULg)
Full Text
See detailPatterns of Loving: Erna Brodber, Nothing's Mat
Romdhani, Rebecca ULg

in SX Salon: A Small Axe Literary Platform (2016), 21

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailMechanoreceptors in the anterior horn of the equine medial meniscus: an immunohistochemical approach
Nemery, Elodie ULg; Gabriel, Annick ULg; Grulke, Sigrid ULg et al

in Anatomia, Histologia, Embryologia (2016), 45

Lameness due to stifle and especially meniscal lesions is frequent in equine species. In humans, mechanoreceptors involved in proprioceptive function are well studied. Given the high incidence of meniscal ... [more ▼]

Lameness due to stifle and especially meniscal lesions is frequent in equine species. In humans, mechanoreceptors involved in proprioceptive function are well studied. Given the high incidence of meniscal injuries in horses, and the lack of information concerning them in equine menisci, our objective was to study these corpuscles in six healthy anterior horns of the equine medial meniscus, which is the most common localisation reported for equine meniscal injuries. Immunohistochemical stainings were performed using antibodies against high molecular weight neurofilaments and glial fibrillary acidic proteins. From a purely fundamental point of view, our work highlights for the first time the presence of Ruffini, Pacini and Golgi corpuscles in equine meniscus. They were found, isolated or in clusters and always located at the vicinity of blood vessels, at the level of the anterior horn of the equine medial meniscus. This morphological approach could serve as a basis for clinical studies, to evaluate the impact of these corpuscles on the poor sportive prognosis in equine meniscal tears. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailInvolvement of Executive Functions in Children’s Metamemory
Geurten, Marie ULg; Catale, Corinne ULg; Meulemans, Thierry ULg

in Applied Cognitive Psychology (2016), 30(1), 70-80

This experiment examined how knowledge of memory strategies and of memory functioning improves during childhood and what variables are involved in this development. Three main aspects of metamemory were ... [more ▼]

This experiment examined how knowledge of memory strategies and of memory functioning improves during childhood and what variables are involved in this development. Three main aspects of metamemory were assessed based on the performance of a group of 100 children (aged 4, 6, 9 and 11 years) on a battery of executive tasks. At the same time, the influence of variables such as intelligence, vocabulary and parental education level was also investigated. Results of mediation analyses reveal that the relation between children’s age and internal strategy knowledge was partially mediated by working memory skills but that executive functions did not mediate the impact of chronological age on children’s knowledge of external strategies or of memory functioning. Additionally, verbal fluency predicted internal and external strategy knowledge. Implications for general learning theories in childhood are discussed [less ▲]

Detailed reference viewed: 26 (8 ULg)
Full Text
Peer Reviewed
See detailDe la perversion au pervers ; du sexuel à l’adaptatif
Englebert, Jérôme ULg

in Psychosomatique Relationnelle (2016), 5(1),

Detailed reference viewed: 99 (24 ULg)
Full Text
Peer Reviewed
See detailDulaglutide (LY-2189265) for the treatment of type 2 diabetes.
Scheen, André ULg

in Expert review of clinical pharmacology (2016), 9(3), 385-99

Dulaglutide is a new once-weekly glucagon-like peptide-1 receptor agonist for the management of hyperglycemia in adult patients with type 2 diabetes. It stimulates dose-dependent insulin secretion and ... [more ▼]

Dulaglutide is a new once-weekly glucagon-like peptide-1 receptor agonist for the management of hyperglycemia in adult patients with type 2 diabetes. It stimulates dose-dependent insulin secretion and reduces glucagon secretion, both in a glucose-dependent manner. Efficacy on blood glucose control and safety were demonstrated in the large AWARD program in type 2 diabetic patients treated with diet, metformin, dual oral therapy or insulin lispro with or without metformin, confirming findings of pilot studies in Caucasian patients and data in Japanese patients. Dulaglutide 1.5 mg once weekly was superior to metformin, sitagliptin, insulin glargine and exenatide twice daily, and non-inferior to liraglutide 1.8 mg once daily regarding the reduction in glycated hemoglobin. A modest but significant weight loss was consistently observed. Most frequent adverse events were transient and generally mild gastrointestinal disturbances. Clinical outcomes of dulaglutide will not be known until the large prospective cardiovascular outcome trial REWIND is complete. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailLymphocytoses B monoclonales : de la revue de la littérature à la pratique de laboratoire.
KEUTGENS, Aurore ULg; Foguenne, Jacques; Gothot, André ULg et al

in Annales de biologie clinique (2016), 74(2), 168-175

Monoclonal B-cell lymphocytosis (MBL) is defined as an asymptomatic condition characterized by the presence of less than 5,000 monoclonal B-cells per microliter and the absence of clinical signs or ... [more ▼]

Monoclonal B-cell lymphocytosis (MBL) is defined as an asymptomatic condition characterized by the presence of less than 5,000 monoclonal B-cells per microliter and the absence of clinical signs or symptoms of a B-cell lymphoproliferative disorder. Most MBL cases involve B cells presenting an identical phenotype to CLL (CLL-like MBL) with a Catovsky-Matutes score of 3 to 5 and share the same chromosomal abnormalities than CLL. Depending on the absolute B cell count, one may distinguish low-count CLL-like MBL (<500 B cells/muL) which have no evidence of progression, no reduction in overall survival, no increase in infection risk and do not require any specific follow-up. Patients with clinical CLL-like MBL (>500 B cells/muL) have a 1% to 2% per year risk of progression to CLL requiring therapy, a higher risk of infectious complications and mortality implicating an annual follow-up by hematologist. MBL may also express other less common phenotypes and are named atypical MBL in case of CD5 antigen expression (Catovsky-Matutes score: 1-2) and non-CLL-like MBL for CD5 negative cases (Catovsky-Matutes score: 0-2). Their poorer prognosis implicates imaging studies, bone marrow biopsy and cytogenetic analysis in addition to physical examination in order to rule out non-hodgkinien lymphoma, and require a more frequent follow-up. This review focuses on key concepts in the classification, diagnosis, monitoring and biology of MBL in laboratory practice. [less ▲]

Detailed reference viewed: 23 (4 ULg)
Full Text
Peer Reviewed
See detailJack-of-all-trades effects drive biodiversity-ecosystem multifunctionality relationships in European forests.
van der Plas, Fons; Manning, Peter; Allan, Eric et al

in Nature communications (2016), 7

There is considerable evidence that biodiversity promotes multiple ecosystem functions (multifunctionality), thus ensuring the delivery of ecosystem services important for human well-being. However, the ... [more ▼]

There is considerable evidence that biodiversity promotes multiple ecosystem functions (multifunctionality), thus ensuring the delivery of ecosystem services important for human well-being. However, the mechanisms underlying this relationship are poorly understood, especially in natural ecosystems. We develop a novel approach to partition biodiversity effects on multifunctionality into three mechanisms and apply this to European forest data. We show that throughout Europe, tree diversity is positively related with multifunctionality when moderate levels of functioning are required, but negatively when very high function levels are desired. For two well-known mechanisms, 'complementarity' and 'selection', we detect only minor effects on multifunctionality. Instead a third, so far overlooked mechanism, the 'jack-of-all-trades' effect, caused by the averaging of individual species effects on function, drives observed patterns. Simulations demonstrate that jack-of-all-trades effects occur whenever species effects on different functions are not perfectly correlated, meaning they may contribute to diversity-multifunctionality relationships in many of the world's ecosystems. [less ▲]

Detailed reference viewed: 15 (5 ULg)
Full Text
Peer Reviewed
See detailIs the Sørensen test valid to assess muscle fatigue of the trunk extensor muscles?
Demoulin, Christophe ULg; Boyer, Mathieu; Duchateau, Jacques et al

in Journal of Back and Musculoskeletal Rehabilitation (2016), 00

BACKGROUND: Very few studies have quantified the degree of fatigue characterized by the decline in the maximal voluntary contraction (MVC) force of the trunk extensors induced by the widely used Sørensen ... [more ▼]

BACKGROUND: Very few studies have quantified the degree of fatigue characterized by the decline in the maximal voluntary contraction (MVC) force of the trunk extensors induced by the widely used Sørensen test. OBJECTIVE: Measure the degree of fatigue of the trunk extensor muscles induced by the Sørensen test. METHODS: Eighty young healthy subjects were randomly divided into a control group (CG) and an experimental group (EG), each including 50% of the two genders. The EG performed an isometric MVC of the trunk extensors (pre-fatigue test) followed by the Sørensen test, the latter being immediately followed by another MVC (post-fatigue test). The CG performed only the preand post-fatigue tests without any exertion in between. RESULTS: The comparison of the pre- and post-fatigue tests revealed a significant (P <0.05) decrease in MVC force normalized by body mass (−13%) in the EG, whereas a small increase occurred in the CG (+2.7%, P = 0.001). CONCLUSIONS: This study shows that the Sørensen test performed until failure in a young healthy population results in a reduced ability of the trunk extensor muscles to generate maximal force, and indicates that this test is valid for the assessment of fatigue in trunk extensor muscles. [less ▲]

Detailed reference viewed: 82 (8 ULg)
Full Text
Peer Reviewed
See detailIn vitro screening of mare's milk antimicrobial effect and antiproliverative activity.
Guri, Anilda; Paligot, Michèle; Crevecoeur, Sébastien ULg et al

in FEMS Microbiology Letters (2016)

Full Text
Peer Reviewed
See detailNew Insight on the Performance of Equity Long/short Investment Styles
Fays, Boris ULg; Hübner, Georges ULg; Lambert, Marie ULg

in Bankers, Markets, Investors (2016), 140(January-February), 34-45

Long-short equity strategies have recently generated exceptional performance raising a set of concerns about the strategies’ propensity to deliver alpha or beta. This paper revisits the performance of ... [more ▼]

Long-short equity strategies have recently generated exceptional performance raising a set of concerns about the strategies’ propensity to deliver alpha or beta. This paper revisits the performance of equity long-short hedge funds across investments styles. We first categorize individual hedge funds with regard to their size and/or value factor investing along the generalization of Sharpe (1992) style analysis. Style weights on size and value factors are used to split the equity long-short universe in 5x5 hedge fund style portfolios. To analyze the performance of each style, we consider two sets of innovative factors. First, we apply sequential Fama-French model of Lambert, Fays and Hübner (2015). Besides, to captures downside and extreme risk embedded in hedge fund strategies we augment the model with the co-skewness and co-kurtosis factors developed by Lambert and Hübner (2013). Under this framework, we perform cross-sectional performance analyses of individual hedge funds as well as time-series analysis on the hedge fund style broad category. Our contributions are threefold; first, our alternative framework significantly improves the explanatory power of the multi-factor model in the context of long-short equity funds, second, considering higher-moment factors aim to capture part of the abnormal return of the downside and extreme risk exposures taken by a fund manager, and finally, long-short equity hedge funds are, to some extent, less exposed to small capitalisation stocks than expected and instead rather prefer higher momentum levels in their strategies. [less ▲]

Detailed reference viewed: 53 (16 ULg)
Full Text
Peer Reviewed
See detailTetraxylopteris Beck emend. Hammond and Berry (2005), the first aneurophytalean genus recorded in Australia
Meyer-Berthaud, Brigitte; Decombeix, Laure; Dunstone, Robert et al

in Review of Palaeobotany and Palynology (2016), 224(Part 1), 54-65

Detailed reference viewed: 20 (3 ULg)
Full Text
Peer Reviewed
See detailUnveiling Network and Service Performance Degradation in the Wild with mPlane
Casas, Pedro; Fiadino, Pierdomenico; Wassermann, Sarah ULg et al

in IEEE Communications Magazine - Network Testing Series (2016)

Unveiling network and service performance issues in complex and highly decentralized systems such as the Internet is a major challenge. Indeed, the Internet is based on decentralization and diversity ... [more ▼]

Unveiling network and service performance issues in complex and highly decentralized systems such as the Internet is a major challenge. Indeed, the Internet is based on decentralization and diversity. However, its distributed nature leads to operational brittleness and difficulty in identifying the root causes of performance degradation. In such a context, network measurements are a fundamental pillar to shed light and to unveil design and implementation defects. To tackle this fragmentation and visibility problem, we have recently conceived mPlane, a distributed measurement platform which runs, collects and analyses traffic measurements to study the operation and functioning of the Internet. In this paper, we show the potentiality of the mPlane approach to unveil network and service degradation issues in live, operational networks, involving both fixed-line and cellular networks. In particular, we combine active and passive measurements to troubleshoot problems in end-customer Internet access connections, or to automatically detect and diagnose anomalies in Internet-scale services (e.g., YouTube) which impact a large number of end-users. [less ▲]

Detailed reference viewed: 46 (2 ULg)
Full Text
Peer Reviewed
See detailModeling heat stress under different environmental conditions
Carabano, Maria-Jesus; Logar, Betka; Bormann, Jeanne et al

in Journal of Dairy Science (2016)

Renewed interest in heat stress effects on livestock productivity derives from climate change, which is expected to increase temperatures and the frequency of extreme weather events. This study aimed at ... [more ▼]

Renewed interest in heat stress effects on livestock productivity derives from climate change, which is expected to increase temperatures and the frequency of extreme weather events. This study aimed at evaluating the effect of temperature and humidity on milk production in highly selected dairy cattle populations across three European regions differing in climate and production systems to detect differences and similarities that can be used to optimize heat stress (HS) effect modeling. Milk, fat and protein test day data from official milk recording for years 1999 to 2010 in four Holstein populations located in the Walloon Region of Belgium (BEL), Luxembourg (LUX), Slovenia (SLO) and Southern Spain (SPA) were merged with temperature and humidity data provided by the state meteorological agencies. After merging, the number of test day records/cows per trait ranged from 686,726/49,655 in SLO to 1,982,047/136,746 in BEL. Values for the daily average and maximum temperature and humidity index (THIavg and THImax) ranges for THIavg/THImax were largest in SLO (22-74/28-84) in SLO and shortest in SPA (39-76/46-83). Change point techniques were used to determine comfort thresholds, which differed across traits and climatic regions. Milk yield showed an inverted U shaped pattern of response across the THI scale with a HS threshold around 73 THImax units. For fat and protein, thresholds were lower than for milk yield and were shifted around 6 THI units towards larger values in SPA compared with the other countries. Fat showed lower HS thresholds than protein traits in all countries. The traditional broken line model was compared to quadratic and cubic fits of the pattern of response in production to increasing heat loads. A cubic polynomial model allowing for individual variation in patterns of response and THIavg as heat load measure showed the best statistical features. Higher/lower producing animals showed less/more persistent production (quantity and quality) across the THI scale. The estimated correlations between comfort and THIavg values of 70 (which represents the upper end of the THIavg scale in BEL-LUX) were lower for BEL-LUX (0.70 - 0.80) than for SPA (0.83 - 0.85). Overall, animals producing in the more temperate climates and semi-extensive grazing systems of BEL and LUX showed HS at lower heat loads and more re-ranking across the THI scale than animals producing in the warmer climate and intensive indoor system of SPA. [less ▲]

Detailed reference viewed: 87 (20 ULg)
Full Text
Peer Reviewed
See detailDementia-specific quality of life instruments: a conceptual analysis
Missotten, Pierre ULg; Dupuis, Gilles; Adam, Stéphane ULg

in International Psychogeriatrics (2016)

Background: Over the past 20 years, many researchers have worked in developing various methods for measuring quality of life (QoL) of people with dementia. The aim of this review is to develop the ... [more ▼]

Background: Over the past 20 years, many researchers have worked in developing various methods for measuring quality of life (QoL) of people with dementia. The aim of this review is to develop the conceptual frameworks of the dementia-specific QoL instruments, to identify their evolution over time and to provide elements of reflection on the QoL concept in dementia and its evaluation. Method: An electronic search was conducted on PsycINFO and MEDLINE databases, from January 1985 to June 2015 using a combination of key words that include quality of life, dementia and review. Result: The analysis of the conceptual frameworks of the eighteen selected dementia-specific QoL tools shows a great diversity in: (1) the QoL definitions (e.g. health-related QoL definitions, QoL definitions based on Lawton’s work or similar to this latter); (2) the theoretical QoL models (e.g. Lawton’ work and modified Lawton, adaptation, personhood); (3) the domains and dimensions; (4) the way to construct the instrument (e.g. development based on literature, opinion of the experts) and (5) the items’ formulation (e.g. use of criterion of intensity or frequency). Conclusion: There are different conceptual frameworks in the dementia-specific QoL measures with improvements over time (e.g. inclusion of interesting concepts such as adaptation, taking into account the views of patients themselves). Each of the conceptual parameters (definitions, models, domains and dimensions) is discussed to identify the scales that are conceptually the strongest. Through their review, recommendations for future instrument refinement and development are discussed and a new QoL definition is proposed. [less ▲]

Detailed reference viewed: 25 (3 ULg)
Full Text
Peer Reviewed
See detailStratigraphy and depositional environments of the Late Famennian (Late Devonian) of Southern Belgium and characterization of the Strud locality
Denayer, Julien ULg; Prestianni, Cyrille; Gueriau, Pierre et al

in Geological Magazine (2016), 153(1), 112-127

The Famennian (Upper Devonian, c. 372 to 359 Ma) strata of Belgium have recently received much attention after the discoveries of early tetrapod remains and outstandingly preserved continental arthropods ... [more ▼]

The Famennian (Upper Devonian, c. 372 to 359 Ma) strata of Belgium have recently received much attention after the discoveries of early tetrapod remains and outstandingly preserved continental arthropods. The Strud locality has yielded a diverse flora and fauna including seed-plants, tetrapods, various placoderm, actinopterygian, acanthodian and sarcopterygian fishes, crustaceans (anostracans, notostracans, conchostracans and decapods) and a putative complete insect. This fossil assemblage is one of the oldest continental – probably fresh-water – ecosystems with a considerable vertebrate and invertebrate diversity. The study of the palaeoenvironment of the Strud locality is crucial because it records one of the earliest and most important phases of tetrapod evolution that took place after their emergence but before their terrestrialization. It raises the question of environmental and ecological conditions for the Devonian aquatic ecosystem and the selection pressures occurring at the onset of tetrapod terrestrialization. The present study characterized the fluvial facies of the Upper Famennian sedimentary rocks of Strud and the surrounding areas. The exceptional preservation of arthropods and plants in the main fossiliferous layers is explained by rapid burial in the fine-grained sediment of the quiet and confined flood plain environment. Newly investigated fossiliferous sections in the Meuse–Samson area led to the description and correlation of key sections (Strud, Wierde and Jausse sections, complemented by the less continuous Haltinne, Huy and Coutisse sections). Moreover, the investigated sections allowed a review of the age of the fossiliferous horizon, which is now definitely considered to be Late Famennian in age. [less ▲]

Detailed reference viewed: 23 (9 ULg)
Full Text
Peer Reviewed
See detailIdentification and frequencies of cystic fibrosis mutations in central Argentina.
Pepermans, Xavier; Mellado, Soledad; Chialina, Sergio et al

in Clinical biochemistry (2016)

Detailed reference viewed: 57 (4 ULg)
Full Text
Peer Reviewed
See detailReal-time Recordings of Migrating Cortical Neurons from GFP and Cre Recombinase Expressing Mice.
Tielens, Sylvia ULg; Godin, Juliette D.; Nguyen, Laurent ULg

in Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] (2016), 74

The cerebral cortex is one of the most intricate regions of the brain that requires elaborate cell migration patterns for its development. Experimental observations show that projection neurons migrate ... [more ▼]

The cerebral cortex is one of the most intricate regions of the brain that requires elaborate cell migration patterns for its development. Experimental observations show that projection neurons migrate radially within the cortical wall, whereas interneurons migrate along multiple tangential paths to reach the developing cortex. Tight regulation of the cell migration processes ensures proper positioning and functional integration of neurons to specific cerebral cortical circuits. Disruption of neuronal migration often leads to cortical dysfunction and/or malformation associated with neurological disorders. Unveiling the molecular control of neuron migration is thus fundamental to understanding the physiological or pathological development of the cerebral cortex. In this unit, protocols allowing detailed analysis of patterns of migration of both interneurons and projection neurons under different experimental conditions (i.e., loss or gain of function) are presented. [less ▲]

Full Text
Peer Reviewed
See detailMesure des flux de CO2 et séquestration de carbone dans les écosystèmes terrestres ouest-africains (Synthèse Bibliographique)
Ago, Expédit Evariste ULg; Agbossou, Euloge Kossi; Ozer, Pierre ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2016), 20(1), 1-15

In West Africa, as elsewhere in other parts of the world, preserving terrestrial ecosystems has proven essential to any emissions mitigation policy for greenhouse gases, notably carbon dioxide. A ... [more ▼]

In West Africa, as elsewhere in other parts of the world, preserving terrestrial ecosystems has proven essential to any emissions mitigation policy for greenhouse gases, notably carbon dioxide. A meaningful assessment of the contribution of a given region to the global carbon cycle implies the need to think in terms of balance, taking into account the totality of the carbon export and import within the ecosystems [less ▲]

Detailed reference viewed: 46 (13 ULg)
Full Text
Peer Reviewed
See detailHow do cumulative live birth rates and cumulative multiple live birth rates over complete courses of assisted reproductive technology treatment per woman compare among registries?
De Neubourg, Diane; Bogaerts, Kris; Blockeel, Christophe et al

in Human Reproduction (2016)

Detailed reference viewed: 14 (5 ULg)
Full Text
Peer Reviewed
See detailGait speed or gait variability, which one to use as a marker of risk to develop Alzheimer's disease ? A pilot study
GILLAIN, Sophie ULg; DRAME, M; LEKEU, Françoise ULg et al

in Aging Clinical and Experimental Research (2016), 28(2), 249-255

Detailed reference viewed: 48 (10 ULg)
Full Text
Peer Reviewed
See detailThe transactional process between the relationships with caregivers and children's externalizing behavior
Roskam, Isabelle; Stievenart, Marie ULg; de Mol, Jan

in Journal of Applied Developmental Psychology (2016), 42

Externalizing behavior (EB) has been found to be pervasive in children across different interactional systems. The transactional model is one of the most interesting and plausible mechanisms explaining ... [more ▼]

Externalizing behavior (EB) has been found to be pervasive in children across different interactional systems. The transactional model is one of the most interesting and plausible mechanisms explaining the development of behavioral problems (Sameroff, 2009). The main goal of the study is to test bidirectional and recursive transactional relations between the quality of the caregiver–child relationship and children's externalizing behavior. The transactional model was tested in three-wave longitudinal cross-lagged models involving 117 children (78.5% boys) aged 4 at the beginning of the study and three caregivers, i.e. their mother, father and teacher. All of the children had been clinically referred for externalizing behavior. Themulti-informant three-wave design was an original feature of this research. The results provided no evidence for a transactional process. The results suggest the singularity of each ofthese three interactional systems. They are discussed from the theoretical viewpoint and in terms of their clinical implications. [less ▲]

Detailed reference viewed: 34 (2 ULg)
Full Text
Peer Reviewed
See detailThe development of the abilities to acquire novel detailed orthographic representations and maintain them in long-term memory
Binamé, Florence ULg; Poncelet, Martine ULg

in Journal of Experimental Child Psychology (2016), 143

Previous studies have clearly demonstrated that the development of orthographic representations relies on phonological recoding. However, substantial questions persist about the remaining unexplained ... [more ▼]

Previous studies have clearly demonstrated that the development of orthographic representations relies on phonological recoding. However, substantial questions persist about the remaining unexplained variance in the acquisition of word-specific orthographic knowledge that is still underspecified. The main aim of this study was to explore whether two cognitive factors—sensitivity to orthographic regularities and short-term memory (STM) for serial order—make independent contributions to the acquisition of novel orthographic representations beyond that of the phonological core component and the level of preexisting word-specific orthographic knowledge. To this end, we had children from second to sixth grades learn novel written word forms using a repeated spelling practice paradigm. The speed at which children learned the word forms and their long-term retention (1 week and 1 month later) were assessed. Hierarchical regression analyses revealed that phonological recoding, preexisting word-specific orthographic knowledge, and order STM explained a portion of the variance in orthographic learning speed, whereas phonological recoding, preexisting word-specific orthographic knowledge, and orthographic sensitivity each explained a portion of variance in the long-term retention of the newly created orthographic representations. A secondary aim of the study was to determine the developmental trajectory of the abilities to acquire novel orthographic word forms over the course of primary schooling. As expected, results showedan effect of age on both learning speed and long-term retention. The specific roles of orthographic sensitivity and order STM as independent factors involved in different steps of orthographic learning are discussed. [less ▲]

Detailed reference viewed: 31 (8 ULg)
Full Text
Peer Reviewed
See detailComment je traite ....... Le delirium chez le patient âgé
CHRISTELBACH, Sophie ULg; ALLEPAERTS, Sophie ULg; PETERMANS, Jean ULg

in Revue Médicale de Liège (2016)

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailScientific Problems Addressed by the Spektr-UV Space Project (World Space Observatory—Ultraviolet)
Boyarchuk, A.A.; others; Gérard, Jean-Claude ULg et al

in Astronomy Reports (2016), 60(1), 1-42

The article presents a review of scientific problems and methods of ultraviolet astronomy, focusing on perspective scientific problems (directions) whose solution requires UV space observatories. These ... [more ▼]

The article presents a review of scientific problems and methods of ultraviolet astronomy, focusing on perspective scientific problems (directions) whose solution requires UV space observatories. These include reionization and the history of star formation in the Universe, searches for dark baryonic matter, physical and chemical processes in the interstellar medium and protoplanetary disks, the physics of accretion and outflows in astrophysical objects, from Active Galactic Nuclei to close binary stars, stellar activity (for both low-mass and high-mass stars), and processes occurring in the atmospheres of both planets in the solar system and exoplanets. Technological progress in UV astronomy achieved in recent years is also considered. The well advanced, international, Russian-led Spektr-UV (World Space Observatory—Ultraviolet) project is described in more detail. This project is directed at creating a major space observatory operational in the ultraviolet (115–310 nm). This observatory will provide an effective, and possibly the only, powerful means of observing in this spectral range over the next ten years, and will be an powerful tool for resolving many topical scientific problems. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailClinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease
SMOLEN, J.S.; COLLAUD BASSET, S.; BOERS, M. et al

in Annals of Rheumatic Diseases (2016)

The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases convened a task force of experts in rheumatoid arthritis (RA) and clinical trial ... [more ▼]

The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases convened a task force of experts in rheumatoid arthritis (RA) and clinical trial methodology to comment on the new draft ‘Guideline on clinical investigation of medicinal products for the treatment of RA’ released by the European Medicines Agency (EMA). Special emphasis was placed by the group on the development of new drugs for the treatment of early RA. In the absence of a clear definition of early RA, it was suggested that clinical investigations in this condition were conducted in disease-modifying antirheumatic drugs naïve patients with no more than 1 year disease duration. The expert group recommended using an appropriate improvement in disease activity (American College of Rheumatology (ACR) or Simplified/Clinical Disease Activity Index (SDAI/CDAI) response criteria) or low disease activity (by any score) as primary endpoints, with ACR/European League Against Rheumatism remission as a secondary endpoint. Finally, as compelling evidence showed that the Disease Acrivity Score using 28-joint counts (DAS28) might not provide a reliable definition of remission, or sometimes even low disease activity, the group suggested replacing DAS28 as a measurement instrument to evaluate disease activity in RA clinical trials. Proposed alternatives included SDAI, CDAI and Boolean criteria. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
Peer Reviewed
See detailOptimization of a cheap and residential small-scale production of edible crickets with local by-products as an alternative protein-rich human food source in Ratanakiri Province (Cambodia)
Caparros Megido, Rudy ULg; Alabi, Taofic ULg; Nieus, Clément et al

in Journal of the Science of Food and Agriculture (2016)

Background - Health status of the indigenous people of the Ratanakiri Province, Cambodia, is significantly lower compared to the rest of the nation. The domestication and mass production of insects may ... [more ▼]

Background - Health status of the indigenous people of the Ratanakiri Province, Cambodia, is significantly lower compared to the rest of the nation. The domestication and mass production of insects may represent a sustainable, cost effective and high quality alternative source of protein to traditional livestock. This study aimed to optimise a cheap and residential cricket breeding system based on unused wild resources. The cricket development, Teleogryllus testaceus (Walker), under seven diets composed of taro aerial parts, young cassava leaves, young cashew leaves and brown rice flour (with or without banana slices), versus a traditionally used broiler feed diet was studied. Results - Cricket mortality was low in all diets, except the two cashew-based diets. Total biomass was significantly higher under the broiler feed, in addition to the two diets containing a combination of cassava leaf powder and brown rice. Yet, crickets fed with the taro diet had the highest percentage of protein. Concerning the breeding system cost, units using cassava leaves were the cheapest ones. Conclusion – Diets based of cassava leaves seems to be the most promising ones. Nevertheless, to produce crickets with a high body mass and a high protein level, a new experiment must be realised in which the cassava leaf maturity will be adapted to fit with the cricket growth stage. Moreover, to reduce the cost of the breeding units, handmade local products should be used instead of purchased components. [less ▲]

Detailed reference viewed: 77 (30 ULg)
Full Text
Peer Reviewed
See detailInfluence of the balls kinematics of axially loaded ball bearings on Coulombic frictional dissipations
Bozet, Jean-Luc ULg; Servais, Christophe ULg

in Journal of Tribology (2016)

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact ... [more ▼]

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact balls kinematics has still to be addressed in depth. This paper proposes a new way to calculate the balls kinematics by using a simplified quasi-static approach for dry lubricated and axially loaded ball bearings. This method does not use the classical restrictive race control assumptions. More specifically, the role played by the balls kinematics is emphasized by means of the power dissipated within contacts between balls and races. The need for a correct evaluation of the balls behavior is illustrated by using an example, viz. a ball bearing of cryogenic engine turbopump. Indeed, the dissipated power is one of the main concerns in this particular case. [less ▲]

Detailed reference viewed: 24 (5 ULg)
Full Text
Peer Reviewed
See detailFurther insights into the metamorphosis process in a carapid fish
Parmentier, Eric ULg

in Journal of Zoology (2015)

Detailed reference viewed: 23 (3 ULg)
Full Text
See detailLe droit constitutionnel de la Principauté de Liège au 18e siècle
Behrendt, Christian ULg; Vandenbosch, Sofia ULg

in Revue Belge de Droit Constitutionnel [= RBDC] (2015), 2015

Detailed reference viewed: 652 (191 ULg)
Full Text
Peer Reviewed
See detailUn moment machiavélien dans la théorie. Sur Althusser
Oulc'hen, Hervé ULg

in Cahiers du GRM (2015), 8

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailLe couplage « Micro-crédit, Micro-assurance santé et Offre des soins » peut améliorer l’accessibilité aux soins de santé de qualité en milieu urbain africain : Résultats d’une expérience menée dans la zone de santé de Bandalungwa à Kinshasa, Congo.
Manzambi Kuwekita, Joseph ULg; Gosset, Christiane ULg; Guillaume, Michèle ULg et al

in Médecine et Santé Tropicales (2015), 25

Summary This study, based on a survey carried out in 2008, examines how coupling «microcredit, micro-insurance and health care» can improve access to quality care in the health zone of Bandalungwa, in ... [more ▼]

Summary This study, based on a survey carried out in 2008, examines how coupling «microcredit, micro-insurance and health care» can improve access to quality care in the health zone of Bandalungwa, in Kinshasa. The bivariate analysis shows a significant association between the increase in purchasing power and realization of benefit (p = 0, 001), achievement of benefit and savings (p = 0, 000) savings and insurance health and improved access to health care: according to the main results, 68.8 %t of borrowers reported an increase in their purchasing power which 81.8% making benefit. Those with savings were 24.7 times more likely to contribute to a health insurance scheme than those without; 71.9% of those who have regularly contributed to health insurance have improved their access to care. Coupling microcredit, health microinsurance and health care can improve access to quality health care at lower cost. This suggests the integration of health insurance in the primary health care system. [less ▲]

Detailed reference viewed: 157 (42 ULg)
Peer Reviewed
See detailCirculating microRNA-based screening tool for breast cancer
Freres, Pierre ULg; Wenric, Stéphane ULg; Boukerroucha, Meriem et al

in Oncotarget (2015)

Circulating microRNAs (miRNAs) are increasingly recognized as powerful biomarkers in several pathologies, including breast cancer. Here, their plasmatic levels were measured to be used as an alternative ... [more ▼]

Circulating microRNAs (miRNAs) are increasingly recognized as powerful biomarkers in several pathologies, including breast cancer. Here, their plasmatic levels were measured to be used as an alternative screening procedure to mammography for breast cancer diagnosis. A plasma miRNA profile was determined by RT-qPCR in a cohort of 378 women. A diagnostic model was designed based on the expression of 8 miRNAs measured first in a profiling cohort composed of 41 primary breast cancers and 45 controls, and further validated in diverse cohorts composed of 108 primary breast cancers, 88 controls, 35 breast cancers in remission, 31 metastatic breast cancers and 30 gynecologic tumors. A receiver operating characteristic curve derived from the 8-miRNA random forest based diagnostic tool exhibited an area under the curve of 0.81. The accuracy of the diagnostic tool remained unchanged considering age and tumor stage. The miRNA signature correctly identified patients with metastatic breast cancer. The use of the classification model on cohorts of patients with breast cancers in remission and with gynecologic cancers yielded prediction distributions similar to that of the control group. Using a multivariate supervised learning method and a set of 8 circulating miRNAs, we designed an accurate, minimally invasive screening tool for breast cancer. [less ▲]

Detailed reference viewed: 55 (16 ULg)
Full Text
Peer Reviewed
See detailReconstruction of the envelope of non-Gaussian structural responses with principal static wind loads
Blaise, Nicolas ULg; Canor, Thomas; Denoël, Vincent ULg

in Journal of Wind Engineering & Industrial Aerodynamics (2015), 149

In current practice, structural engineers commonly focus on the wind-resistant design by means of static wind loads. In case of non-Gaussianities, there is room for improvement to properly derive these ... [more ▼]

In current practice, structural engineers commonly focus on the wind-resistant design by means of static wind loads. In case of non-Gaussianities, there is room for improvement to properly derive these static loads. First, this paper extends in a non-Gaussian context the concept of the load-response correlation (LRC) method establishing equivalent static wind loads (ESWLs). This is done by a proper recourse to the new concept of conditional expected static wind load and a proposed bicubic model for the joint and conditional distribution functions. Second, this paper investigates the envelope reconstruction problem targeting the efficient reconstruction of the envelope values of a set of non-Gaussian structural responses by means of principal static wind loads (PSWLs). They have been introduced in a Gaussian context and are obtained by a singular value decomposition of ESWLs. This paper addresses the extension of PSWLs to non-Gaussian structural responses, as well. The developments apply to structures with a linear behavior and subjected to an aerodynamic pressure field exhibiting mildly to strongly non-Gaussian features. In this context, the well-known load-response correlation and conditional sampling methods are used for comparisons. This study is undertaken for quasi-static analysis of structures and is illustrated on a low-rise building. [less ▲]

Detailed reference viewed: 22 (4 ULg)
Full Text
Peer Reviewed
See detailAnticoherence of spin states with point-group symmetries
Baguette, Dorian ULg; Damanet, François ULg; Giraud, Olivier et al

in Physical Review A (2015), 92

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana ... [more ▼]

We investigate multiqubit permutation-symmetric states with maximal entropy of entanglement. Such states can be viewed as particular spin states, namely anticoherent spin states. Using the Majorana representation of spin states in terms of points on the unit sphere, we analyze the consequences of a point-group symmetry in their arrangement on the quantum properties of the corresponding state. We focus on the identification of anticoherent states (for which all reduced density matrices in the symmetric subspace are maximally mixed) associated with point-group-symmetric sets of points. We provide three different characterizations of anticoherence and establish a link between point symmetries, anticoherence, and classes of states equivalent through stochastic local operations with classical communication. We then investigate in detail the case of small numbers of qubits and construct infinite families of anticoherent states with point-group symmetry of their Majorana points, showing that anticoherent states do exist to arbitrary order. [less ▲]

Detailed reference viewed: 35 (6 ULg)
Full Text
Peer Reviewed
See detailSkin ultrastructural similarities between fibromyalgia and Ehlers-Danlos syndrome hypermobility type
Hermanns-Lê, Trinh ULg; PIERARD, Gérald ULg

in Journal of osteoarthritis (2015), 1(1),

Fibromyalgia (FM) and hypermobility type Ehlers-Danlos syndrome (EDSH) share a series of common clinical signs. A clinical distinction between both diseases is occasionally difficult to be established ... [more ▼]

Fibromyalgia (FM) and hypermobility type Ehlers-Danlos syndrome (EDSH) share a series of common clinical signs. A clinical distinction between both diseases is occasionally difficult to be established. The physical changes observed in the mechanical properties of skin and joints do not distinctly distinguish these disorders. In addition, similar ultrastructural dermal changes are observed in both EDSH and some FM cases. The molecular alterations remain largely undisclosed in both diseases. As a result, EDSH remains undiagnosed in some FM patients. This condition deteriorates quality of life and possibly leads to prominent health problems. [less ▲]

Detailed reference viewed: 76 (2 ULg)
Full Text
Peer Reviewed
See detailAbility of Tuta absoluta (Lepidoptera: Gelechiidae) to develop on alternative host plant species
Bawin, Thomas ULg; Dujeu, David; De Backer, Lara ULg et al

in Canadian Entomologist (2015)

The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host ... [more ▼]

The tomato leafminer, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is a widespread devastating pest reported to develop on economically important solanaceous crops. The characterization of its host range could help to understand and prevent the dispersion behavior of the insect in the environment. In this study, the ability of T. absoluta to develop on 12 cultivated or non-cultivated plants including Solanaceae, Chenopodiaceae, Convolvulaceae, Fabaceae and Malvaceae species under laboratory conditions was assessed. For each plant species, we monitored the development times of immature stages, survival, sex ratios and adult fecundity rates. All the 6 tested non-solanaceous plants, including Chenopodium, Convolvulus and Malva species, were not able to sustain (i.e. allow growth and development) T. absoluta larvae. Among Solanaceae, Solanum species were the most suitable host plants for the pest, but others could be opportunistically colonized with fewer incidences. T. absoluta appears to be strongly related to solanaceous plants which would predominantly support self-sustaining field populations. Preventing crop infestation by removing potential host plants in the immediate field vicinity and culture rotations with non-solanaceous crops is of primary importance. [less ▲]

Detailed reference viewed: 54 (11 ULg)
Full Text
See detailDendroécologie du hêtre en forêt de Soignes : Les cernes des arbres nous renseignent sur les changements récents et futurs
Latte, Nicolas ULg; Kint, Vincent; Drouet, Thomas et al

in FORÊT.NATURE (2015), 137(Octobre-Novembre-Décembre), 24-37

La dendroécologie combine la dendrochronologie et l’écologie forestière. Elle a permis d’analyser les cernes des hêtres de la forêt de Soignes et de comparer les tendances dans le contexte plus large des ... [more ▼]

La dendroécologie combine la dendrochronologie et l’écologie forestière. Elle a permis d’analyser les cernes des hêtres de la forêt de Soignes et de comparer les tendances dans le contexte plus large des hêtraies de Belgique. Depuis la fin des années ‘70, le hêtre devient de plus en plus sensible au climat, surtout en Soignes. L’augmentation de la fréquence et de l’intensité des sécheresses printanières et des canicules ont affecté négativement la croissance annuelle des hêtres. Les prévisions climatiques pour le 21e siècle présage une rapide aggravation. Les risques encourus par l’essence aboutissent à de nouvelles réflexions sur la gestion de la hêtraie de Soignes. Pour les peuplements existants : une sylviculture dynamique avec des éclaircies fortes et fréquentes afin de limiter la concurrence pour les ressources et favoriser la croissance individuelle des arbres. Pour la régénération des vieilles hêtraies : les remplacer par d’autres essences plus tolérantes ou favoriser le mélange et confiner le hêtre aux surfaces limitées des stations les plus fraîches. Un risque mesuré pourrait être pris en regard du rôle patrimonial des hêtraies cathédrales en Soignes. Toutefois, ce faciès peut être obtenu avec d’autres essences. [less ▲]

Detailed reference viewed: 50 (18 ULg)
Full Text
Peer Reviewed
See detailReal-time measurement of temperature variation during nanosecond pulsed laser induced contamination deposition
Kokkinos, Dimitrios ULg; Gailly, Patrick ULg; Georges, Marc ULg et al

in Applied Optics (2015), 54(36), 10579

In this paper a study of the heat generation during UV Laser Induced Contamination (LIC) and potentially resulting subsequent thermal damage is presented. This becomes increasingly interesting when optics ... [more ▼]

In this paper a study of the heat generation during UV Laser Induced Contamination (LIC) and potentially resulting subsequent thermal damage is presented. This becomes increasingly interesting when optics with delicate coatings are involved. During LIC radiation can interact with outgassing molecules both in the gas phase and at the surface, triggering chemical and photo-fixation reactions. This is a major hazard, in particular for laser units operating under vacuum conditions such as for space applications. The intense photon flux not only affects the contaminant deposition rate but also alters their chemical structure that can increase their absorption coefficient. Over cumulative irradiation shots these molecules formed deposits that increasingly absorb photons and produce heat as a by-product of de-excitation eventually leading to thermal damage. One could better asses the risk of the latter with the knowledge of temperature during the contamination process. For this purpose thermoreflectance technique is used here to estimate the temperature variation from pulse to pulse during contamination deposition through the analysis of a temperature-dependent surface reflectance signal. [less ▲]

Detailed reference viewed: 61 (23 ULg)
Full Text
Peer Reviewed
See detailPrediction of the post-dilution hematocrit during cardiopulmonary bypass. Are new formulas needed?
ERPICUM, Marie ULg; Dardenne, Nadia ULg; HANS, Grégory ULg et al

in Perfusion (2015)

Objectives: Predicting the post-dilution hematocrit is an important tool to avoid preventable anemia or unnecessary transfusion. Simplified empirical formulas currently used for such a prediction may lead ... [more ▼]

Objectives: Predicting the post-dilution hematocrit is an important tool to avoid preventable anemia or unnecessary transfusion. Simplified empirical formulas currently used for such a prediction may lead to large errors. We aimed to improve the accuracy of these formulas by a better estimation of the dilution volume and the patient circulatory blood volume. Methods: We compared the estimation accuracy of two formulas, using fixed (formula A) versus estimated (formula D) dilution volume and patient circulatory blood volume for 100 cardiac interventions. The difference between predicted and measured HctT1 was considered as “good” if less than 0.5%, “moderate” between 0.5 and 2% and “poor” if higher than 2%. The influence of the body mass index (BMI) on patient blood volume estimation was explored by categorized groups’ comparison. Results: The mean difference between predicted and measured HctT1 differed significantly between formulas A and D. Formula A didn’t differ from HctT1 (p=0.19, IC95% [-0.89-0.18]), but a significant and higher underestimation was observed in the BMI⩽25 group compared to the other BMI groups (p<0.001). Formula D overestimated HctT1 (p<0.001, IC95% [1.01-1.93]) without a difference between the BMI groups. No difference was observed in their overall proportions of good (11 vs 10%), moderate (44 vs 46%) and poor predictions (47 vs 44%) (p=0.117). Conclusions: Formulas used for post-dilution hematocrit prediction lead to major estimation errors and a risk of inadequate transfusion practices. Estimations performed by experienced clinicians could not minimize these biases in all clinical cases as significant errors remain, with potential clinical impact. No estimation formula should be used as a hard tool for transfusing patients, but rather as a guide to predicting the probability of transfusion requirement. [less ▲]

Detailed reference viewed: 14 (4 ULg)
Full Text
Peer Reviewed
See detailMannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study.
Mandal, Jyotshna; Malla, Bijaya; Steffensen, Rudi et al

in Respiratory research (2015), 16

BACKGROUND: Functional deficiency of mannose-binding lectin (MBL) may contribute to the pathogenesis of chronic obstructive pulmonary disease. We hypothesized that specific MBL2 gene polymorphisms and ... [more ▼]

BACKGROUND: Functional deficiency of mannose-binding lectin (MBL) may contribute to the pathogenesis of chronic obstructive pulmonary disease. We hypothesized that specific MBL2 gene polymorphisms and circulating MBL protein levels are associated with clinically relevant outcomes in the Predicting Outcome using systemic Markers In Severe Exacerbations of COPD PROMISE-COPD cohort. METHODS: We followed 277 patients with stable COPD GOLD stage II-IV COPD over a median period of 733 days (IQR 641-767) taking survival as the primary outcome parameter. Patients were dichotomized as frequent (>/= 2 AECOPD/year) or infrequent exacerbators. Serum MBL levels and single nucleotide polymorphisms of the MBL2 gene were assessed at baseline. RESULTS: The MBL2-HYPD haplotype was significantly more prevalent in frequent exacerbators (OR: 3.33; 95% CI, 1.24-7.14, p = 0.01). The median serum MBL concentration was similar in frequent (607 ng/ml, [IQR; 363.0-896.0 ng/ml]) and infrequent exacerbators (615 ng/ml, [IQR; 371.0-942.0 ng/ml]). Serum MBL was not associated with lung function characteristics or bacterial colonization in sputum. However, high serum MBL at stable state was associated with better survival compared to low MBL (p = 0.046, log rank test). CONCLUSIONS: In COPD, the HYPD haplotype of MBL2 gene is associated with frequent exacerbations and high serum MBL is linked to increased survival. The PROMISE-COPD study was registered at www.controlled-trials.com under the identifier ISRCTN99586989. [less ▲]

Detailed reference viewed: 15 (1 ULg)
Full Text
Peer Reviewed
See detailWater-Energy Nexus in Shared River Basins: How Hydropower Shapes Cooperation and Coordination
Kouangpalath, Phimthong ULg; Meijer, Karen

in Topical Issue on Sustainability in the Water-Energy-Food Nexus (2015), 2

The construction of hydropower plants on transboundary rivers is seldom done with equal benefits to all riparians, and therefore presents coordination and cooperation challenges. Without a supra-national ... [more ▼]

The construction of hydropower plants on transboundary rivers is seldom done with equal benefits to all riparians, and therefore presents coordination and cooperation challenges. Without a supra-national authority in charge of transboundary river basins, coordination between sectors (water, energy and environment) and cooperation between countries largely depends on willingness of the individual nation states and the power relations between these countries. This paper discusses how the interests and relative power positions of actors in transboundary water management shape the outcomes, and what roles are played by River Basin Organisations and foreign investors (especially in hydropower development). These issues are illustrated with examples from the Mekong river in Southeast Asia (Laos, Thailand, Cambodia and Vietnam), the Euphrates-Tigris (Turkey, Syria, Iraq, Iran and Kuwait) and the Çoruh in Turkey and Georgia. [less ▲]

Detailed reference viewed: 42 (0 ULg)
Full Text
Peer Reviewed
See detailL'Italia e i processi di decolonizzazione : il caso del Congo belga (1957-1960)
Genin, Vincent ULg

in Ventunesimo Secolo (2015), 36(Anno XIV (Giugno 2015)), 105-138

This article, based on unpusblished archives, is devoted to the question : what was the impact of the decolonization of the Belgian Congo on Italian foreign Policy ((1957-1960) ? Facing a shared reality ... [more ▼]

This article, based on unpusblished archives, is devoted to the question : what was the impact of the decolonization of the Belgian Congo on Italian foreign Policy ((1957-1960) ? Facing a shared reality with Belgium, the aim of this research is to study the attitude of Italian foreign policy, forced to maintain a balance between its position in the UN ; its relation with Belgium ; and the need to maintain influence, mainly through Financial penetration, in the newly independent Congo [less ▲]

Detailed reference viewed: 22 (3 ULg)
Full Text
Peer Reviewed
See detailAnalysis of the adoption of the passion fruit (Passflora Edulis) in farming systems, Matongo Burundi
Bashangwa Mpozi, Bosco ULg; Musabanganji, Edouard ULg; Ndimanya, Patrice et al

in Poljoprivreda i Sumarstvo = Agriculture and Forestry (2015), 61(4), 117-124

The commercial potential of passion fruit is expanding as demand for both fresh fruit and processed juice is increasing in Burundi. Due to the current situation with an unstable market of traditional ... [more ▼]

The commercial potential of passion fruit is expanding as demand for both fresh fruit and processed juice is increasing in Burundi. Due to the current situation with an unstable market of traditional crops for export, farmers in Matongo have embraced passion fruit as a new source of household income. As the crop generates substantial revenues for farmers, wholesalers and processors, it is important to sustain this sector. The purpose of this research was to compare four variants of diffusionist arguments (age, sex, household size and level of education) and their expression into adoption. Comparative descriptive statistical analysis between adopters and non-adopters to test the essential factors, and participatory survey methods for gathering information were used. Our results showed a highly significant difference between the category of adopters and non-adopters at p < 0.01. However, no significant difference was found between adopters and non-adopters within level of education. Data on the level of education demonstrated that those with little or no education adopted more passion fruit [illiterates (48.9%) and primary level (45.9%)] than these with secondary level (5.2%). The heads of household adopters and non-adopters are mainly men at a rate of 83.7 and 88.3 %, and household size was not a discriminating factor. The factors that promote the adoption of passion fruit are high yield and continuous production, high market demand and permanent source of revenue. Defining only a few variables to analyse the adoption trend could mislead our findings. A participatory approach seems most appropriate for understanding adoption and non-adoption of innovation [less ▲]

Detailed reference viewed: 7 (1 ULg)
Full Text
Peer Reviewed
See detailPublic health impact and cost-effectiveness of dairy products supplemented with vitamin D in prevention of osteoporotic fractures
Ethgen, Olivier ULg; Hiligsmann, Mickaël; Burlet, Nansa et al

in Archives of Public Health (2015)

Background: Dietary sources of calcium and vitamin D are recommended as a first-line strategy in prevention of osteoporosis-related fractures but their public health and economic impact has never been ... [more ▼]

Background: Dietary sources of calcium and vitamin D are recommended as a first-line strategy in prevention of osteoporosis-related fractures but their public health and economic impact has never been studied. Methods: We designed a population-based model to forecast the potential health outcomes and medical effectiveness of the daily administration of dairy supplements containing 800 IU of vitamin D and 1 g of calcium in cohorts of subjects, from both genders, aged 50, 60, 70 and 80 years. Annual costs of dairy products were tested at €150, €250 and €350. Results: In total, the daily intake of vitamin-D rich dairy products reduces by 30,376 and 16,105 events the number of osteoporotic fractures in women and men respectively and permits to gain 6605 and 6144 life-years, in women and men respectively. This intervention is cost-effective from 70 years on in the general population and from 60 years on in patients at increased risk of osteoporotic fractures. Conclusion: The recommendation to use dairy products as the preferred source of calcium and vitamin D in aging males and females is supported by public health and health economic analyses. [less ▲]

Detailed reference viewed: 9 (7 ULg)
Full Text
Peer Reviewed
See detailLe droit de rétrocession, une garantie constitutionnelle pour l'exproprié?
Vrancken, Martin ULg; Pâques, Michel ULg

in Administration Publique: Revue du Droit Public et des Sciences Administratives (2015)

Revue de droit public et des sciences administratives

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailIntegration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer
Pineda San Juan, Silvia ULg; Real, Francisco X; Kogevinas, Manolis et al

in PLoS Genetics (2015)

Detailed reference viewed: 35 (5 ULg)
Full Text
Peer Reviewed
See detailImpact of cyclonic and anticyclonic activity on Greenland ice sheet surface mass balance variation during 1980–2013
Chen, L.; Fettweis, Xavier ULg; Knudsen, E. et al

in International Journal of Climatology (2015)

The Greenland ice sheet (GrIS) has experienced dramatic ice loss during recent decades, but the drivers of the surface mass balance (SMB) variation remain unclear. From a dynamical perspective ... [more ▼]

The Greenland ice sheet (GrIS) has experienced dramatic ice loss during recent decades, but the drivers of the surface mass balance (SMB) variation remain unclear. From a dynamical perspective, extratropical cyclones and anticyclones are the major systems influencing Greenland weather conditions. Seasonal cyclonic and anticyclonic activities have been quantified for the area of 50°–90°N, 80°W–10°E during 1980–2013. Based on a singular value decomposition (SVD) analysis, we investigated the role of synoptic scale cyclonic and anticyclonic activities in determining snow accumulation (SA) and surface air temperature (SAT). Thus, the SA-driven and melt-driven SMB variability has been determined. SA-related synoptic patterns identified from the leading and the second SVD modes explain up to 80% of the inter-annual SMB variance, especially in southern and northwestern Greenland, where we found the largest and second largest amount of annual SA. SAT-related patterns account for up to 80% of the inter-annual SMB variation along the west and northwest coast of Greenland, where significant surface mass loss has been observed over the last decades. It should be noted that the negative phase of the SA-related pattern derived from the first SVD mode in June-July-August and the positive phase of the SAT-related (anti)cyclonic patterns have occurred more frequently since 2005, meaning that the phase change of these patterns has made a major contribution to the accelerated GrIS surface ice loss during recent years. [less ▲]

Detailed reference viewed: 53 (3 ULg)
Full Text
Peer Reviewed
See detailSerum calcitriol concentrations measured with a new direct automated assay in a large population of adult healthy subjects and in various clinical situations
Souberbielle, JC; CAVALIER, Etienne ULg; DELANAYE, Pierre ULg et al

in Clinica Chimica Acta (2015), 451 (Pt B)

The measurement of calcitriol [1,25(OH2)D], is important for the differential diagnosis of several disorders of calcium/phosphorus metabolism but is time-consuming and tricky. We measured serum calcitriol ... [more ▼]

The measurement of calcitriol [1,25(OH2)D], is important for the differential diagnosis of several disorders of calcium/phosphorus metabolism but is time-consuming and tricky. We measured serum calcitriol with a new automated direct assay on the Liaison XL platform in 888 healthy French Caucasian subjects aged 18–89 years, 32 patients with a surgically-proven PHPT, 32 pregnant women at the end of the first and at the end of the third trimester, and 24 dialysis patients before and after one year of supplementationwith vitamin D3 or placebo. The mean calcitriol concentration (±SD) in the healthy population was 52.9 ± 14.5 ng/L with a 95% CI interval of 29–83.6 ng/L. In PHPT patients, calcitriol concentration was 81.6±29.0 ng/L, 15 of them (46.9%) having a concentration N83.6 ng/L. In pregnant women, calcitriol was 80.4 ± 26.4 ng/L at the end of the first trimester, and 113.1±33.0 ng/L at the end of the third trimester, 12 (37.5%) and 26 (81.3%) of them having a calcitriol concentration N83.6 ng/L at the first and third trimesters respectively. In 14 dialysis patients, calcitriol was 9.5±7.7 ng/L and rose to 19.3 ng/L after one year of supplementation with 50,000 IU vitamin D3/month. In 10 other dialysis patients, calcitriol was 9.9±2.9 ng/L and remained stable (12.4±3.7 ng/L) after one year of placebo. In conclusion, this new automated calcitriol assay, in addition to presenting excellent analytical performances, gives the expected variations in patients compared to “normal” values obtained in an extensive reference population [less ▲]

Detailed reference viewed: 21 (4 ULg)
Full Text
Peer Reviewed
See detailFraming the Concept of Citizenship in a Contested Nation-State: Reflections on Kosovo
Mazur Kumric, Nives ULg

in Pécs Journal of International and European Law (2015), (II), 70-88

Since the inception of the Republic of Kosovo in February 2008, the contouring of its statehood has been predominantly affected by four interwoven factors: the partial recognition of its sovereignty ... [more ▼]

Since the inception of the Republic of Kosovo in February 2008, the contouring of its statehood has been predominantly affected by four interwoven factors: the partial recognition of its sovereignty, perplexed inter-ethnic relations, profound international interference and parallel jurisdictions with the Republic of Serbia. The efforts put forth to conceptualise the meaning and scope of Kosovo citizenship in such a sensitive socio-political environment have proved particularly challenging. This paper aims to provide an analytical framework for determining essential elements of Kosovo citizenship, with particular emphasis on its practical and ideological implications for the multicultural, yet ethnically divided society. This is done through an assessment of the key nation-constituting legal norms as well as the deep-rooted ethnic tensions sparked by conflicting perceptions of Kosovo's statehood by the majority (Kosovo Albanian) and minority (Kosovo Serbian) population. By formal definition, Kosovo is an indivisible state of all citizens, however, polarised majority-minority interests have impinged the constitutionally guaranteed civic spirit of the entity, thereby threatening not only national, but also wider international security and integrity. With the purpose of determining and delineating labyrinthine intersections of a contested nation-state, citizenship, 'communities' and security, the paper offers a comprehensive theoretical analysis of the respective quadrilateral nexus. [less ▲]

Detailed reference viewed: 33 (0 ULg)
Full Text
Peer Reviewed
See detailInfluence of process operating conditions on solvent thermal and oxidative degradation in post-combustion CO2 capture
Léonard, Grégoire ULg; Crosset, Cyril; Toye, Dominique ULg et al

in Computers & Chemical Engineering (2015), 83

The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data ... [more ▼]

The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data, monoethanolamine degradation is included into a CO2 capture process model. The influence of operating conditions on solvent loss is validated with pilot plant data from literature. Predicted solvent consumption rates are in better agreement with plant data than any previous work, and pathways are discussed to further refine the model. Oxidative degradation in the absorber is the largest cause of solvent loss while thermal degradation does not appear as a major concern. Using a single model, the process exergy requirement decreases by 10.8% and the solvent loss by 11.1% compared to our base case. As a result, this model provides a practical tool to simultaneously minimize the process energy requirement and the solvent consumption in post-combustion CO2 capture plants with amine solvents. [less ▲]

Detailed reference viewed: 95 (20 ULg)
Full Text
Peer Reviewed
See detailAssessing the O2 budget under sea ice: An experimental and modelling approach
Moreau, S.; Kaartokallio, H.; Vancoppenolle, M. et al

in Elementa: Science of the Anthropocene (2015), 3(000080),

The objective of this study was to assess the O2 budget in the water under sea ice combining observations and modelling. Modelling was used to discriminate between physical processes, gas-specific ... [more ▼]

The objective of this study was to assess the O2 budget in the water under sea ice combining observations and modelling. Modelling was used to discriminate between physical processes, gas-specific transport (i.e., ice-atmosphere gas fluxes and gas bubble buoyancy) and bacterial respiration (BR) and to constrain bacterial growth efficiency (BGE). A module describing the changes of the under-ice water properties, due to brine rejection and temperature-dependent BR, was implemented in the one-dimensional halo-thermodynamic sea ice model LIM1D. Our results show that BR was the dominant biogeochemical driver of O2 concentration in the water under ice (in a system without primary producers), followed by gas specific transport. The model suggests that the actual contribution of BR and gas specific transport to the change in seawater O2 concentration was 37% during ice growth and 48% during melt. BGE in the water under sea ice, as retrieved from the simulated O2 budget, was found to be between 0.4 and 0.5, which is in line with published BGE values for cold marine waters. Given the importance of BR to seawater O2 in the present study, it can be assumed that bacteria contribute substantially to organic matter consumption and gas fluxes in ice-covered polar oceans. In addition, we propose a parameterization of polar marine bacterial respiration, based on the strong temperature dependence of bacterial respiration and the high growth efficiency observed here, for further biogeochemical ocean modelling applications, such as regional or large-scale Earth System models [less ▲]

Detailed reference viewed: 21 (1 ULg)
Full Text
Peer Reviewed
See detailThe return of Turkey to the Western Balkans: a challenge or an opportunity for the European Union?
Lika, Liridon ULg

in Politikon: IAPSS Journal of Political Science (2015)

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailAutosomal-Recessive Intellectual Disability with Cerebellar Atrophy Syndrome Caused by Mutation of the Manganese and Zinc Transporter Gene SLC39A8.
Boycott, Kym M.; Beaulieu, Chandree L.; Kernohan, Kristin D. et al

in American journal of human genetics (2015), 97(6), 886-93

Manganese (Mn) and zinc (Zn) are essential divalent cations used by cells as protein cofactors; various human studies and animal models have demonstrated the importance of Mn and Zn for development. Here ... [more ▼]

Manganese (Mn) and zinc (Zn) are essential divalent cations used by cells as protein cofactors; various human studies and animal models have demonstrated the importance of Mn and Zn for development. Here we describe an autosomal-recessive disorder in six individuals from the Hutterite community and in an unrelated Egyptian sibpair; the disorder is characterized by intellectual disability, developmental delay, hypotonia, strabismus, cerebellar atrophy, and variable short stature. Exome sequencing in one affected Hutterite individual and the Egyptian family identified the same homozygous variant, c.112G>C (p.Gly38Arg), affecting a conserved residue of SLC39A8. The affected Hutterite and Egyptian individuals did not share an extended common haplotype, suggesting that the mutation arose independently. SLC39A8 is a member of the solute carrier gene family known to import Mn, Zn, and other divalent cations across the plasma membrane. Evaluation of these two metal ions in the affected individuals revealed variably low levels of Mn and Zn in blood and elevated levels in urine, indicating renal wasting. Our findings identify a human Mn and Zn transporter deficiency syndrome linked to SLC39A8, providing insight into the roles of Mn and Zn homeostasis in human health and development. [less ▲]

Detailed reference viewed: 7 (1 ULg)
Full Text
Peer Reviewed
See detailEvolution of the Northern Rockweed, Fucus distichus, in a Regime of Glacial Cycling: Implications for Benthic Algal Phylogenetics
Laughinghouse, Haywood, Dail; Müller, Kirsten; Adey, Walter et al

in PLoS ONE (2015), 10(12), 0143795

Northern hemisphere rockweeds (Fucus) are thought to have evolved in the North Pacific and then spread to the North Atlantic following the opening of the Bering Strait. They have dispersed and widely ... [more ▼]

Northern hemisphere rockweeds (Fucus) are thought to have evolved in the North Pacific and then spread to the North Atlantic following the opening of the Bering Strait. They have dispersed and widely speciated in the North Atlantic and its tributary seas. Fucus distichus is likely near the ancestral member of this genus, and studies have shown that there are several species/subspecies in this complex (i.e. F. evanescens and F. gardneri). We used phylogenetic and haplotype analyses to test the phylogenetic relationships and biogeogra- phy of F. distichus. Our data and subsequent analyses demonstrate that, unlike previous studies that lacked samples from an extensive geographical area of the Arctic and Subarc- tic, there is a distinct Arctic haplotype that is the source of subspecies in both the North Pacific and North Atlantic. Fucus distichus occupies a low tide zone habitat, and in Arctic/ Subarctic regions it is adapted to the severe stress of sea ice coverage and disturbance dur- ing many months per year. We hypothesize that the very large geographic area of Arctic and Subarctic rocky shores available to this species during interglacials, supported by large Arctic/Subarctic fringe areas as well as unglaciated refugia during glacial cycles, provided a robust population and gene pool (described by the Thermogeographic Model). This gene pool dilutes that of the more fragmented and area-limited Temperate/Boreal area popula- tions when they are brought together during glacial cycles. We suggest that similar subspe- cies complexes for a variety of Arctic/Subarctic shore biota should be examined further in this context, rather than arbitrarily being split up into numerous species. [less ▲]

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailAnalytical Tools and Strategic Approach to Detect Poor Quality Medicines, Identify Unknown Components, and Timely Alerts for Appropriate Measures: Case Study of Antimalarial Medicines
Habyalimana, Védaste ULg; Mbinze Kindenge, Jérémie; Kalenda Tshilombo, Nicodème ULg et al

in American Journal of Analytical Chemistry (2015), 6

Nowadays, the circulation of poor quality medicines is becoming an alarming worldwide phenomenon with serious public health and socio-economic concerns. The situation is particularly critical in ... [more ▼]

Nowadays, the circulation of poor quality medicines is becoming an alarming worldwide phenomenon with serious public health and socio-economic concerns. The situation is particularly critical in developing countries where drug quality assurance and regulatory systems for drug manufacturing, importation, distribution and sales are weak. A sustained vigilance on poor quality medicines that regroup counterfeit/falsified, substandard and degraded medicines is therefore required to ensure patient safety and genuine medicines integrity. A case situation is illustrated including a strategic approach and analytical tools that were found useful to detect poor quality medicines, identify unknown components, and timely alerts for appropriate measures against the spread of those harmful products. Several suspected medicines randomly sampled in several strategic Rwandan areas were firstly check-controlled by means of visual inspection and then applying several analytical techniques from simple to more complex ones. The following medicines were studied: quinine sulfate tablets, artemisinin-based combination tablets, and artesunate powders for injection. Taking into account the pharmaceutical forms and the chemical characteristics, the following tests were applied: uniformity of mass, friability, disintegration, fluorescence, identification and assay. They were followed by more complex analytical techniques that allowed more comprehension of abnormal findings among which the presence of a wrong active pharmaceutical ingredient in quinine sulfate tablets which is mainly discussed in this paper to illustrate a strategic approach and various analytical tools that can be used in detecting and identifying unknown component in poor quality medicines. [less ▲]

Detailed reference viewed: 26 (9 ULg)
Full Text
Peer Reviewed
See detailKroniek van het Nederlandse nationaliteitsrecht 2014-2015
Vonk, Olivier ULg

in Asiel- en Migrantenrecht (2015)

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailTRAPPIST photometry and imaging monitoring of comet C/2013 R1 (Lovejoy): Implications for the origin of daughter species
Opitom, Cyrielle ULg; Jehin, Emmanuel ULg; Manfroid, Jean ULg et al

in Astronomy and Astrophysics (2015), 584

We report the results of the narrow-band photometry and imaging monitoring of comet C/2013 R1 (Lovejoy) with the robotic telescope TRAPPIST (La Silla observatory). We gathered around 400 images over 8 ... [more ▼]

We report the results of the narrow-band photometry and imaging monitoring of comet C/2013 R1 (Lovejoy) with the robotic telescope TRAPPIST (La Silla observatory). We gathered around 400 images over 8 months pre- and post-perihelion between September 12, 2013 and July 6, 2014. We followed the evolution of the OH, NH, CN, C[SUB]3[/SUB], and C[SUB]2[/SUB] production rates computed with the Haser model, as well as the evolution of the dust production. All five gas species display an asymmetry about perihelion, since the rate of brightening is steeper than the rate of fading. The study of the coma morphology reveals gas and dust jets that indicate one or several active zone(s) on the nucleus. The dust, C[SUB]2[/SUB], and C[SUB]3[/SUB] morphologies present some similarities, while the CN morphology is different. OH and NH are enhanced in the tail direction. The study of the evolution of the comet activity shows that the OH, NH, and C[SUB]2[/SUB] production rate evolution with the heliocentric distance is correlated to the dust evolution. The CN and, to a lesser extent, the C[SUB]3[/SUB] do not display such a correlation with the dust. This evidence and the comparison with parent species production rates indicate that C[SUB]2[/SUB] and C[SUB]3[/SUB], on one hand, and OH and NH, on the other, could be - at least partially - released from organic - rich grains and icy grains. On the contrary, all evidences point to HCN being the main parent of CN in this comet. [less ▲]

Detailed reference viewed: 43 (10 ULg)
Full Text
Peer Reviewed
See detailLes lieux d’habitation des écrivains belges francophones à Bruxelles (1930-1960). Premiers jalons pour une histoire sociogéographique
Debroux, Tatiana; Vanderpelen-Diagre, Cécile; Dozo, Björn-Olav ULg

in Textyles : Revue des Lettres Belges de Langue Française (2015), 47

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailLarger and faster: revised properties and a shorter orbital period for the WASP-57 planetary system from a pro-am collaboration
Southworth, John; Mancini, L.; Tregloan-Reed, J. et al

in Monthly Notices of the Royal Astronomical Society (2015), 454

Transits in the WASP-57 planetary system have been found to occur half an hour earlier than expected. We present 10 transit light curves from amateur telescopes, on which this discovery was based, 13 ... [more ▼]

Transits in the WASP-57 planetary system have been found to occur half an hour earlier than expected. We present 10 transit light curves from amateur telescopes, on which this discovery was based, 13 transit light curves from professional facilities which confirm and refine this finding, and high-resolution imaging which show no evidence for nearby companions. We use these data to determine a new and precise orbital ephemeris, and measure the physical properties of the system. Our revised orbital period is 4.5 s shorter than found from the discovery data alone, which explains the early occurrence of the transits. We also find both the star and planet to be larger and less massive than previously thought. The measured mass and radius of the planet are now consistent with theoretical models of gas giants containing no heavy-element core, as expected for the subsolar metallicity of the host star. Two transits were observed simultaneously in four passbands. We use the resulting light curves to measure the planet's radius as a function of wavelength, finding that our data are sufficient in principle but not in practise to constrain its atmospheric properties. We conclude with a discussion of the current and future status of transmission photometry studies for probing the atmospheres of gas-giant transiting planets. [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailThe HARPS-N Rocky Planet Search. I. HD 219134 b: A transiting rocky planet in a multi-planet system at 6.5 pc from the Sun
Motalebi, F.; Udry, S.; Gillon, Michaël ULg et al

in Astronomy and Astrophysics (2015), 584

We know now from radial velocity surveys and transit space missions that planets only a few times more massive than our Earth are frequent around solar-type stars. Fundamental questions about their ... [more ▼]

We know now from radial velocity surveys and transit space missions that planets only a few times more massive than our Earth are frequent around solar-type stars. Fundamental questions about their formation history, physical properties, internal structure, and atmosphere composition are, however, still to be solved. We present here the detection of a system of four low-mass planets around the bright (V = 5.5) and close-by (6.5 pc) star HD 219134. This is the first result of the Rocky Planet Search programme with HARPS-N on the Telescopio Nazionale Galileo in La Palma. The inner planet orbits the star in 3.0935 ± 0.0003 days, on a quasi-circular orbit with a semi-major axis of 0.0382 ± 0.0003 AU. Spitzer observations allowed us to detect the transit of the planet in front of the star making HD 219134 b the nearest known transiting planet to date. From the amplitude of the radial velocity variation (2.25 ± 0.22 ms[SUP]-1[/SUP]) and observed depth of the transit (359 ± 38 ppm), the planet mass and radius are estimated to be 4.36 ± 0.44 M[SUB]⊕[/SUB] and 1.606 ± 0.086 R[SUB]⊕[/SUB], leading to a mean density of 5.76 ± 1.09 g cm[SUP]-3[/SUP], suggesting a rocky composition. One additional planet with minimum-mass of 2.78 ± 0.65 M[SUB]⊕[/SUB] moves on a close-in, quasi-circular orbit with a period of 6.767 ± 0.004 days. The third planet in the system has a period of 46.66 ± 0.08 days and a minimum-mass of 8.94 ± 1.13 M[SUB]⊕[/SUB], at 0.233 ± 0.002 AU from the star. Its eccentricity is 0.46 ± 0.11. The period of this planet is close to the rotational period of the star estimated from variations of activity indicators (42.3 ± 0.1 days). The planetary origin of the signal is, however, thepreferred solution as no indication of variation at the corresponding frequency is observed for activity-sensitive parameters. Finally, a fourth additional longer-period planet of mass of 71 M[SUB]⊕[/SUB] orbits the star in 1842 days, on an eccentric orbit (e = 0.34 ± 0.17) at a distance of 2.56 AU. The photometric time series and radial velocities used in this work are available in electronic form at the CDS via anonymous ftp to <A href="http://cdsarc.u-strasbg.fr">http://cdsarc.u-strasbg.fr</A> (ftp://130.79.128.5) or via <A href="http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/584/A72">http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/584/A72</A> [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailDrug-polymer electrostatic complexes as new structuring agents for the formation of drug-loaded ordered mesoporous silica
Molina, Emilie; Warnant, Jérôme; Mathonnat, Mélody et al

in Langmuir (2015), 31(47), 12839-12844

Using aminoglycoside antibiotics as drug models, it was shown that electrostatic complexes between hydrophilic drugs and oppositely charged double-hydrophilic block copolymers can form ordered mesophases ... [more ▼]

Using aminoglycoside antibiotics as drug models, it was shown that electrostatic complexes between hydrophilic drugs and oppositely charged double-hydrophilic block copolymers can form ordered mesophases. This phase behaviour was evidenced by using poly(acrylic acid)-block-poly(ethylene oxide) block copolymers in the presence of silica precursors and, this allowed preparing drug-loaded mesoporous silica directly from the drug-polymer complexes. The novel synthetic strategy of the hybrid materials is highly efficient, avoiding waste and multi-step processes; it also ensures optimal drug loading and provides pH-dependence of the drug release from the materials. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailPolarization microlensing in the quadruply imaged broad absorption line quasar H1413+117
Hutsemekers, Damien ULg; Sluse, Dominique ULg; Braibant, Lorraine ULg et al

in Astronomy and Astrophysics (2015), 584

We have obtained spectropolarimetric observations of the four images of the gravitationally lensed broad absorption line quasar H1413+117. The polarization of the microlensed image D is significantly ... [more ▼]

We have obtained spectropolarimetric observations of the four images of the gravitationally lensed broad absorption line quasar H1413+117. The polarization of the microlensed image D is significantly different, both in the continuum and in the broad lines, from the polarization of image A, which is essentially unaffected by microlensing. The observations suggest that the continuum is scattered off two regions, spatially separated, and producing roughly perpendicular polarizations. These results are compatible with a model in which the microlensed polarized continuum comes from a compact region located in the equatorial plane close to the accretion disk and the non-microlensed continuum from an extended region located along the polar axis. Based on observations made with ESO Telescopes at the Paranal Observatory (Chile). ESO program ID: 386.B-0337. [less ▲]

Detailed reference viewed: 17 (7 ULg)
Full Text
Peer Reviewed
See detailA cross-sectional study to evaluate factors related to condom use with commercial sexual partners in workers from Ecuadorian companies
Cabezas, Maria C.; Fornasini, Marco; Dardenne, Nadia ULg et al

in BMC Public Health (2015), 15(1),

Detailed reference viewed: 21 (1 ULg)
Full Text
Peer Reviewed
See detailAssessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey
Bruyère, Olivier ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in European Geriatric Medicine (2015)

Introduction: Several tools are available for the assessment of muscle mass, muscle strength and physical performance in clinical research. However, few data are available on the usage of these tools in ... [more ▼]

Introduction: Several tools are available for the assessment of muscle mass, muscle strength and physical performance in clinical research. However, few data are available on the usage of these tools in clinical practice. Methods: This study aimed to assess their usage by means of a large online international survey. Since sarcopenia is a specific condition where the assessment of muscle mass, muscle strength and physical performance is important, the survey also assessed the tools used for the diagnosis of this geriatric syndrome. Results: The survey was completed by 255 clinicians from 55 countries across 5 continents. Among these clinicians with geriatrics, rheumatology and endocrinology as major fields of interest, 53.3% assess muscle mass in daily practice, 54.5% muscle strength and 71.4% physical performance. However, the tools used are very different and no single tool is used by all clinicians. The tools and the cut-off values used by clinicians to diagnose sarcopenia are also heterogeneous. Conclusion: Because some tools used for the assessment of muscle mass, muscle strength or physical performance in daily practice are less validated than others, a greater awareness from the clinicians of the importance of using appropriate tools is needed [less ▲]

Detailed reference viewed: 32 (4 ULg)
Full Text
Peer Reviewed
See detailTransformed mineral phases during clay ceramic firing
El Ouahabi, Meriam ULg; Daoudi, Lachen; Hatert, Frédéric ULg et al

in Clays and Clay Minerals (2015), 62(6), 470478

Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating ... [more ▼]

Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating. A major challenge is to predict the phase transformations in clay ceramics. The aims are to establish reference data of ceramics products that can be formed based on the mineralogical composition of the local raw materials. These data, in turn, can be compared with the archaeological ceramics in order to study their origins. The mineralogical compositions and transformations during the firing (550 to 1100ºC under oxidizing conditions) of seven clayey materials sampled from the main clay deposits of Northern Morocco were evaluated by X-ray powder diffraction. Two groups of clays were evidenced according to the type of neoformed high-temperature minerals: non-calcareous clays and calcareous clays. For the non-calcareous raw materials, spinel is produced at 950°C. Cristobalite and mullite were formed above 1000ºC from clays that contain illite, kaolinite and chlorite. In clays containing vermiculite and high amount of chlorite, hematite was formed from 950°C. Firing of calcareous clays at temperatures > 950ºC yielded Ca-silicates (diopside, gehlenite and wollastonite), spinel, cristobalite, hematite and feldspars. Mullite may also form in the calcareous clay products, when the carbonates content exceeds 10%. [less ▲]

Detailed reference viewed: 221 (60 ULg)
Full Text
See detailLa médecine a plus besoin de contrôle qualité et d'humanité que d'informatisation
Jamoulle, Marc ULg

in Ethica Clinica (2015), 80

La santé est un état de résistance. Résistance à la maladie bien sûr. Résistance aussi à la violence et au harcèlement, résistance aux drogues, résistance à l’exploitation, résistance à la mal bouffe ... [more ▼]

La santé est un état de résistance. Résistance à la maladie bien sûr. Résistance aussi à la violence et au harcèlement, résistance aux drogues, résistance à l’exploitation, résistance à la mal bouffe, résistance à la pollution, résistance aux conditions de logement désastreuses, résistance au marché pharmaceutique, y compris résistance à la marchandisation de la santé et donc résistance parfois à la médecine elle-même. Quelques farfelus en mal de marché pensent que les systèmes électroniques actuels et futurs, vont être capables de remplacer le médecin. Ils imaginent la médecine, ils ne la connaissent pas.Donc je vais vous raconter des histoires vraies, pour vous faire voir ce métier –médecin de famille – comme ce qu’il est vraiment ; exigeant, difficile, complexe, déroutant et non remplaçable par des machines. Je disais donc résistance, voyons voir quelques réflexions et lettres ou notes écrites dans les derniers mois pour l’un ou l’autre patient. [less ▲]

Detailed reference viewed: 432 (4 ULg)
Full Text
Peer Reviewed
See detailPRISE EN CHARGE DES TUMEURS EPITHELIALES THYMIQUES
PAULUS, Astrid ULg; SIBILLE, Anne ULg; BOURHABA, Maryam ULg et al

in Revue Médicale de Liège (2015), 70(12), 623-8

Thymic epithelial tumors (TET) are rare. Their optimal care is still poorly defined because of their rarity and of the resulting difficulty to conceive large clinical trials. This review of the literature ... [more ▼]

Thymic epithelial tumors (TET) are rare. Their optimal care is still poorly defined because of their rarity and of the resulting difficulty to conceive large clinical trials. This review of the literature presents the current clinical and therapeutic data on this form of tumors and underlines the need for a multidisciplinary approach to advanced stage TET. Three clinical situations can be encountered: encapsuled tumors lead to radical surgery; tumors associated with capsular invasion justify a postoperative radiotherapy; advanced stages require a multimodal treatment by chemotherapy, possibly completed by surgery and adjuvant radiotherapy. Besides systemic chemotherapies, the place of new therapeutic strategies, such as somatostatin analogues and targeted treatments, requires to be defined. Treatment of late stage TET is based upon a multidisciplinary dialogue, ideally by a reference team. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailDosage de la lumière pour maintenir la coexistence d’espèces d’ombre et de demi-ombre dans la régénération de la futaie irrégulière
Ligot, Gauthier ULg; Balandier, Philippe; Courbaud, Benoît et al

in Revue Forestière Française (2015), 3

Detailed reference viewed: 38 (5 ULg)
Full Text
Peer Reviewed
See detail“Public-based-Learning”: The Place of Publics in Exploring Environmental Controversies for Pedagogical Purposes
Melard, François ULg; Denayer, Dorothée ULg; Semal, Nathalie ULg

in International Journal of Environmental and Science Education (2015), 10(6), 905-920

This article examines a 15 year-old master level seminar dedicated to the exploration of local and complex environmental issues marked by scientific or technological uncertainties. Following a pragmatic ... [more ▼]

This article examines a 15 year-old master level seminar dedicated to the exploration of local and complex environmental issues marked by scientific or technological uncertainties. Following a pragmatic learning approach, we focus our discussion on a triadic relationship between supervisors, students and various concerned publics. A local flood management controversy in Belgium will help to illustrate our approach and point to some learning outcomes. On the basis of this pedagogical experience, we propose to shift from Problem-based-learning towards Public-based-learning that rests on the comparison of the various ways a problem is defined by publics. This comparative approach allows us to deduce a plurality of modes of involvement mobilized in the management of the environmental problems. [less ▲]

Detailed reference viewed: 38 (8 ULg)
Full Text
Peer Reviewed
See detailQuantum manifestations of classical nonlinear resonances
Wisniacki, Diego A.; Schlagheck, Peter ULg

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2015), 92

When an integrable classical system is perturbed, nonlinear resonances are born, grow, and eventually disappear due to chaos. In this paper the quantum manifestations of such a transition are studied in ... [more ▼]

When an integrable classical system is perturbed, nonlinear resonances are born, grow, and eventually disappear due to chaos. In this paper the quantum manifestations of such a transition are studied in the standard map. We show that nonlinear resonances act as a perturbation that break eigenphase degeneracies for unperturbed states with quantum numbers that differ in a multiple of the order of the resonance. We show that the eigenphase splittings are well described by a semiclassical expression based on an integrable approximation of the Hamiltonian in the vicinity of the resonance. The morphology in phase space of these states is also studied. We show that the nonlinear resonance imprints a systematic influence in their localization properties [less ▲]

Detailed reference viewed: 12 (0 ULg)
Full Text
Peer Reviewed
See detailMultivariate coefficients of variation: Comparison and influence functions
Aerts, Stéphanie ULg; Haesbroeck, Gentiane ULg; Ruwet, Christel ULg

in Journal of Multivariate Analysis (2015), 142

In the univariate setting, coefficients of variation are well-known and used to compare the variability of populations characterized by variables expressed in different units or having really different means ... [more ▼]

In the univariate setting, coefficients of variation are well-known and used to compare the variability of populations characterized by variables expressed in different units or having really different means. When dealing with more than one variable, the use of such a relative dispersion measure is much less common even though several generalizations of the coefficient of variation to the multivariate setting have been introduced in the literature. In this paper, the lack of robustness of the sample versions of the multivariate coefficients of variation (MCV) is illustrated by means of influence functions and some robust counterparts based either on the Minimum Covariance Determinant (MCD) estimator or on the S estimator are advocated. Then, focusing on two of the considered MCV’s, a diagnostic tool is derived and its efficiency in detecting observations having an unduly large effect on variability is illustrated on a real-life data set. The influence functions are also used to compute asymptotic variances under elliptical distributions, yielding approximate confidence intervals. Finally, simulations are conducted in order to compare, in a finite sample setting, the performance of the classical and robust MCV’s in terms of variability and in terms of coverage probability of the corresponding asymptotic confidence intervals. [less ▲]

Detailed reference viewed: 102 (32 ULg)