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See detailMacroevolutionary analysis of the tempo of diversification in snappers and fusiliers (Percomorpha: Lutjanidae)
Frederich, Bruno ULg; Santini, Francesco

in Belgian Journal of Zoology (in press)

The percomorph fish family Lutjanidae (snappers and fusiliers) includes about 135 reef-dwelling species, mainly confined to tropical and subtropical marine waters. The great majority of snappers are ... [more ▼]

The percomorph fish family Lutjanidae (snappers and fusiliers) includes about 135 reef-dwelling species, mainly confined to tropical and subtropical marine waters. The great majority of snappers are active predators feeding on fishes or crustaceans, even though some species, including the fusiliers (Caesioninae), have evolved zooplanktivory. Lutjanids show a great diversity of habitat preferences, based on depth segregation and distribution across reef and associated habitats (e.g. mangroves, seagrass beds, estuaries). In spite of their great ecological and economic importance little is known about the tempo of evolution in this group. The present study provides the most comprehensive molecular phylogeny to date for lutjanids, including 70% of extant species and 19 of the 21 currently described genera. We time-calibrated our molecular tree using the oldest described lutjanid fossils, and show how this group likely originated during the Late Cretaceous to Early Paleocene. Lutjanids experienced significant radiation during the Late Eocene and Early Oligocene, in contrast to a pattern of Late Oligocene/Miocene radiation observed in many other reef-associated groups. The time-tree allows us to investigate the tempo of diversification, and our results suggest a variation in the rate of speciation during the evolution of the major clade formed by “lutjanins and caesionins”. Variation in diet and life history strategies could explain this clade-specific dynamic, even though future phylogenetic comparative studies combining additional ecological and morphological data are needed to test this hypothesis. [less ▲]

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See detailFluid and Electrolytes (Na, Cl and K) in Paediatric Parenteral Nutrition
Jochum, Franck; Moltu, Sissel; SENTERRE, Thibault ULg et al

in Clinical Nutrition (in press)

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See detailMacro-nutrient concentrations in Antarctic pack ice: Overall patterns and overlooked processes
Fripiat, François ULg; Meiners, K.M.; Vancoppenolle, M. et al

in Elementa: Science of the Anthropocene (in press)

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See detailFocus sur les lymphocytes T dans la maladie du greffon contre l'hôte après allogreffe de cellules soucges hématopoïétiques: implications pour de nouvelles stratégies de prévention
Vrancken, L; Delens, Loïc ULg; BEGUIN, Yves ULg et al

in Oncol. Hematol. (in press)

Malgré les stratégies de prévention actuelles, la maladie du greffon contre l’hôte (greffe-versus-hôte, GVH) aiguë (GVHa) reste une complication sévère et fréquente de l’allogreffe de cellules souches ... [more ▼]

Malgré les stratégies de prévention actuelles, la maladie du greffon contre l’hôte (greffe-versus-hôte, GVH) aiguë (GVHa) reste une complication sévère et fréquente de l’allogreffe de cellules souches hématopoïétiques. Bien que la physiopathologie de celle-ci ne reste que partiellement élucidée à ce jour, il est classiquement admis que les lymphocytes T (LT) jouent un rôle important dans son processus biologique. Les progrès récents de l’immunologie des LT dans la GVHa ont permis de diversifier les pistes visant à prévenir la survenue de cette complication post-greffe. Plusieurs approches sont en cours d’exploration dans des essais cliniques avec des résultats encourageant tels que la manipulation ex vivo des LT avant leur transfert chez le patient afin de leur faire exprimer des gènes suicide, l’élimination in vivo des LT proliférant directement après la greffe, l’inhibition de l’activation des LT en interférant avec les voies de signalisation en aval du TCR ou celles induites par les cytokines, l’induction de l’anergie des LT en bloquant les signaux de costimulation, le blocage de l’adressage des LT vers les organes lymphoïdes secondaires et les tissus cibles, la promotion de l’immunotolérance par la perfusion de lymphocytes T régulateurs ou par l’utilisation d’agents favorisant leur différenciation et leurs fonctions in vivo et la modulation de l’expression génique des cellules immunitaires par des modulateurs épigénétiques. Outre la prévention de la GVHa, le défi des nouvelles stratégies consiste également à ne pas compromettre l’effet bénéfique de la greffe contre la tumeur ni la reconstitution des défenses anti-infectieuses. [less ▲]

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See detailLandslide risk reduction measures: a review of practices and challenges for the tropics
Maes, Jan; Kervyn, Matthieu; de Hontheim, Astrid et al

in Progress in Physical Geography (in press)

The overall objective of this review is to gain insights into landslide risk reduction measures that are applied or recommended in tropical landslide-prone countries, and the challenges at play. More ... [more ▼]

The overall objective of this review is to gain insights into landslide risk reduction measures that are applied or recommended in tropical landslide-prone countries, and the challenges at play. More specifically, this review aims to (i) presenting an overview of recent studies on landslides and landslide risk reduction in these countries, (ii) exploring the factors controlling the publication output on landslides and landslide risk reduction, (iii) reviewing the various landslide risk reduction measures recommended and implemented, and (iv) identifying the bottlenecks for the implementation of these strategies. A compilation of recommended and implemented landslide risk reduction measures in 99 landslide-prone tropical countries was made, based on an extensive review of scientific literature (382 publications). The documented measures are analysed Corresponding author: Jan Maes, Department of Earth & Environmental Sciences, KU Leuven, Celestijnenlaan 200E 03.256, Heverlee B-3001, Belgium. Email: maes.jan@kuleuven.be Progress in Physical Geography 1–31 ª The Author(s) 2017 Reprints and permission: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/0309133316689344 journals.sagepub.com/home/ppg using a scheme of risk reduction measures that combines classifications of the Hyogo Framework for Action and the SafeLand project. Our literature review shows that the factors influencing the number of publications on landslides and landslide risk reduction per country are (in order of importance) the absolute physical exposure of people to landslides, the population number and the Human Development Index of a country. The ratio of publications on landslide risk reduction versus publications on landslides for landslide-prone tropical countries does not vary much between these countries (average: 0.28). A significant fraction (0.30) of all known landslide hazard reduction measures are neither implemented nor recommended according to our review. The most recommended landslide risk reduction component is ‘risk management and vulnerability reduction’ (0.38). However, the most implemented component is ‘risk assessment’ (0.57). Overall, the ratio of implemented versus recommended landslide risk reduction measures in the tropics is low (<0.50) for most landslide risk reduction components, except for ‘risk assessment’ (3.01). The most cited bottlenecks for implementing landslide risk reduction measures are scientific (0.30) and political (0.29) in nature. [less ▲]

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See detailPIV-based estimation of unsteady loads on a flat plate at high angle of attack using momentum equation approaches
Guissart, Amandine ULg; Bernal, Luis; Dimitriadis, Grigorios ULg et al

in Experiments in Fluids (in press)

This work presents, compares and discusses results obtained with two indirect methods for the cal culation of aerodynamic forces and pitching moment from 2D Particle Image Velocimetry (PIV) measurements ... [more ▼]

This work presents, compares and discusses results obtained with two indirect methods for the cal culation of aerodynamic forces and pitching moment from 2D Particle Image Velocimetry (PIV) measurements. Both methodologies are based on formulations of the momentum balance: the integral Navier-Stokes equations and the “flux equation” proposed by Noca et al. (1999), which has been extended to the computation of moments. The indirect methods are applied to spatio-temporal data for different separated flows around a plate with a 16:1 chord-to-thickness ratio. Experimental data are obtained in a water channel for both a plate undergoing a large amplitude imposed pitching motion and a static plate at high angle of attack. In addition to PIV data, direct measurements of aerodynamic loads are carried out to assess the quality of the indirect calculations. It is found that indirect methods are able to compute the mean and the temporal evolution of the loads for two-dimensional flows with a reasonable accuracy. Nonetheless, both methodologies are noise sensitive and, the parameters impacting the computation should thus be chosen carefully. It is also shown that results can be improved through the use of Dynamic Mode Decomposition (DMD) as a pre-processing step. [less ▲]

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See detailOvertopping induced failure of non-cohesive, homogenous fluvial dikes
Rifai, Ismail ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Research (in press)

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of ... [more ▼]

Accurate predictions of breach characteristics are necessary to reliably estimate the outflow hydrograph and the resulting inundation close to fluvial dikes. Laboratory experiments on the breaching of sand-filled fluvial dikes were performed, considering a flow parallel to the dike axis. The breach was triggered by overtopping of the dike crest. A detailed monitoring of the transient evolution of the breach geometry was conducted, providing key insights into the gradual and complex processes involved in fluvial dike failure. The breach develops in two phases: (1) the breach becomes gradually wider and deeper eroding on the downstream side along the main channel, and (2) breach widening controlled by side slope failures, continuing in the downstream direction only. Increasing the inflow discharge in the main channel, the breach formation time decreases significantly and the erosion occurs preferentially on the downstream side. The downstream boundary condition has a strong influence on the breach geometry and the resulting outflow hydrograph. [less ▲]

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See detailExperimental validation of heat transport modelling in district heating networks.
Sartor, Kevin ULg

in Energy (in press)

District heating networks (DHN) are generally considered as a convenient, economic and environmental-friendly way to supply heat to a large amount of buildings. Some modelling methods are required to ... [more ▼]

District heating networks (DHN) are generally considered as a convenient, economic and environmental-friendly way to supply heat to a large amount of buildings. Some modelling methods are required to consider the dynamic behaviour of district heating networks to design them correctly, spare the investment costs and limit the heat losses related to the use of a too high operating temperatures. For the same reasons, the DHN control or retrofit of installations also requires the assessment of the DHN dynamic behaviour. To achieve this, the heat transport in DHN, which is one of the key issues in the behaviour of a whole centralized heating system, has to be correctly modelled. Previous work evidenced current limitations of one dimensional finite volume method to model heat transport in pipes and proposed an alternative method considering the thermal losses and the inertia of the pipes. The present contribution intends to experimentally validate this model on a test rig available at the Thermodynamics laboratory of the University of Liège (ULg, Belgium) and on an existing district heating network. For both experimental facilities, the current model shows good agreement between the experimental data and the simulation results for a large range of water velocities. Moreover, it is shown that the thermal inertia of the pipe has a significant influence on the outlet pipe temperature profile. [less ▲]

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See detailMaximum energy dissipation to explain velocity fields in shallow reservoirs
Westhoff, Martijn; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Journal of Hydraulic Research (in press)

Shallow reservoirs are often used as sediment traps or storage basins, in which sedimentation depends on the flow pattern: Short rectangular reservoirs reveal a straight jet from inlet to outlet with on ... [more ▼]

Shallow reservoirs are often used as sediment traps or storage basins, in which sedimentation depends on the flow pattern: Short rectangular reservoirs reveal a straight jet from inlet to outlet with on both sides identical recirculation zones. In longer reservoirs, the main jet reattaches to the side of the reservoir leading to a small and a large recirculation zone. Previous studies found an empirical geometric relation describing the switch between these two flow patterns. In this study, we demonstrate, with a simple analytical model, that this switch coincides with a maximization of energy dissipation in the shear layer between the main jet and recirculation zones: Short reservoirs dissipate more energy when the flow pattern is symmetric, while longer reservoirs dissipate more energy with an asymmetric pattern. This approach enables to predict the flow patterns without detailed knowledge of small scale processes, potentially useful in the early phase of reservoir design. [less ▲]

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See detailL'Halys chez Hérodote
Leloux, Kevin ULg

in Studia Hercynia (in press)

This paper analyses the Halys River’ description made by Herodotus in his Histories. This study focuses on the several references made by the Father of History in his work. It will examine the part the ... [more ▼]

This paper analyses the Halys River’ description made by Herodotus in his Histories. This study focuses on the several references made by the Father of History in his work. It will examine the part the river took in his vision of the politic, ethnic and geographic state in the historian’s mind and the problems that arise by this presentation. Finally, this article will demonstrate that every crossing of the Halys River made by the Barbarians were a bad omen for the Greeks of Asia Minor and in Greece itself. [less ▲]

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See detailPsychological interventions influence patients' attitudes and beliefs about their chronic pain.
VANHAUDENHUYSE, Audrey ULg; Gillet, Aline; MALAISE, Nicole ULg et al

in Journal of Traditional and Complementary Medicine (in press)

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See detailStein's method for comparison of univariate distributions
Ley, Christophe; Reinert, Gesine; Swan, Yvik ULg

in Probability Surveys (in press)

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See detailInfluence of the secondary endosymbiont Serratia Symbiotica on the resistance to the parasitism in the aphid Acyrthosiphon pisum
Attia, Sabrine; Foray, Vincent; Louâpre, Philippe et al

in Journal of Entomology and Zoology Studies (in press)

Aphids have an obligate association with the primary symbiont Buchnera aphidicola and is known to affect aphid fitness. Aphids commonly harbour other facultative bacterial endosymbionts and may benefit ... [more ▼]

Aphids have an obligate association with the primary symbiont Buchnera aphidicola and is known to affect aphid fitness. Aphids commonly harbour other facultative bacterial endosymbionts and may benefit from their presence through increased resistance to parasitoids [1]. Present results suggest that the ability of hosts to defend against natural enemies depend not only on the presence of symbionts but also on the host genotype. Aphids represent a complex micro-environment for the parasitoid larvae and both the aphid physiology and endosymbiont influence their survival until mummification. [less ▲]

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See detailSpatiotemporal variation of drought characteristics in the context of climate change in the Huang-Huai-Hai Plain, China
Li, Xiang-Xiang; Ju, Hui; Garré, Sarah ULg et al

in Journal of Integrative Agriculture (in press)

Understanding the potential drought characteristics under climate change is essential for reducing vulnerability and establishing adaptation strategies, especially in the Huang-Huai-Hai Plain (3H Plain ... [more ▼]

Understanding the potential drought characteristics under climate change is essential for reducing vulnerability and establishing adaptation strategies, especially in the Huang-Huai-Hai Plain (3H Plain) which is the grain production base in China. In this paper, the variation of drought characteristics including drought event frequency, duration, severity and intensity for the past 50 years (1961-2010) and future scenarios (2010-2099) based on observed meteorological data and RCP 8.5 projections were investigated, respectively. Firstly, the applicability of three climatic drought indices including the Standardized Precipitation Index (SPI), the Standardized Precipitation Evapotranspiration Index based on the Penman–Monteith equation (SPEI-PM) and the Thornthwaite equation (SPEI-TH) were compared in tracing recorded agricultural drought areas. Then, the drought characteristics including drought event, duration, severity and intensity using “run theory” was analyzed for both historical observations and future RCP 8.5 scenarios based on the proper index. Correlation analysis between drought indexes and agricultural drought areas showed that SPEI-PM performed better than SPI and SPEI-TH in the 3H Plain. Based on the results of SPEI-PM, droughts over the past 50 years have experienced reduced drought with shorter durations, and weaker severity and intensity. However, for the future RCP 8.5 scenario, drought is predicted to rise in frequency, duration, severity and intensity from 2010-2099 although drought components during the 2010-2039 were milder compared to historical conditions. This study highlights that the estimations for atmospheric evaporative demand would bring in differences in long term drought trend of drought indexes and consequently the applicability in 3H Plain. The results of this paper can help inform researchers and local policy makers to establish drought risk management strategies. [less ▲]

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See detailTHE BATTLE OF THE ECLIPSE (MAY 28, 585 BC): A Discussion of the Lydo-Median treaty and the Halys border
Leloux, Kevin ULg

in Polemos (in press)

In his Book I, Herodotus relates the war between Lydia of Alyattes and Media of Cyaxares. This war ended with the well-known occurrence of the total solar eclipse, which astronomical researchers propose ... [more ▼]

In his Book I, Herodotus relates the war between Lydia of Alyattes and Media of Cyaxares. This war ended with the well-known occurrence of the total solar eclipse, which astronomical researchers propose to date to 585 BC. After these hostilities, a treaty between the two kingdoms was concluded, and was sealed by a royal wedding. This paper analyzes this event, better known as the “battle of the eclipse”. It will revisit the problem of the location of the battle and that of the identity of the Lydian and Median kings who reigned during this conflict. The paper will study the role that the eclipse played on the conclusion of hostilities and its impact on the minds of the Greeks; it will also examine the nature of the treaty concluded between the Lydians and the Medes. Finally, the paper will examine the problem of the Halys border that separated the Lydian and the Median kingdoms, modern scholars asserting that this border was chosen during the Lydo-Median treaty. This examination will allow us to study the view of the ethnic, geographical and political space that the river played in Herodotus’s mind. [less ▲]

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See detailEnergy in Paediatric Parenteral Nutrition
Joosten, Koen; Embleton, Nick; Yan, W et al

in Clinical Nutrition (in press)

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See detailOn the Zero Defect Conjecture
Labbé, Sébastien ULg; Starosta, Stepan; Pelantova, Edita

in European Journal of Combinatorics (in press)

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See detailExperimental and Numerical Study of Mini-UAV Propeller Performance in Oblique Flow
Theys, Bart; Dimitriadis, Grigorios ULg; Hendrick, Patrick et al

in Journal of Aircraft (in press)

This paper presents the modelling of the performance of small propellers used for Vertical Take Off and Landing Micro Aerial Vehicles (VTOL MAVs) operating at low Reynolds numbers and in oblique flow ... [more ▼]

This paper presents the modelling of the performance of small propellers used for Vertical Take Off and Landing Micro Aerial Vehicles (VTOL MAVs) operating at low Reynolds numbers and in oblique flow. Blade Element Momentum Theory (BEMT), Vortex Lattice Method (VLM) and momentum theory for oblique flow are used to predict propeller performance. For validation, the predictions for a commonly used propeller for VTOL MAVs are compared to a set of wind tunnel experiments. Both BEMT and VLM succeed in predicting correct trends of the forces and moments acting upon the propeller shaft, although accuracy decreases significantly in oblique flow. For the dataset analysed here, combining the available data of the propeller in purely axial flow with momentum theory for oblique flow and applying a correction factor for the wake skew angle results in more accurate performance estimates at all elevation angles. [less ▲]

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See detailSublime Gaps: the Absence of Closure in the Metaphysical Detective Story
Dechene, Antoine ULg

in Sillages critiques (in press)

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See detailEvidence for a latitudinal diversity gradient in liverworts and hornworts
Wang, J.; Vanderpoorten, Alain ULg; Hagborg, A. et al

in Journal of Biogeography (in press)

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See detailProjections photographiques et cinéma des premiers temps : La houillère de Gustave Marissiaux et les origines du cinéma minier
Mélon, Marc-Emmanuel ULg

in Intermédialités : Histoire et Théorie des Arts, des Lettres et des Techniques = Intermediality: History and Theory of the Arts, Literature and Technologies (in press)

Les spectacles de projection conçus par Gustave Marissiaux entre 1903 et 1926, en particulier le vaste documentaire intitulé "La houillère" (1905) est ici inscrit dans une histoire sociale des images ... [more ▼]

Les spectacles de projection conçus par Gustave Marissiaux entre 1903 et 1926, en particulier le vaste documentaire intitulé "La houillère" (1905) est ici inscrit dans une histoire sociale des images projetées et mis en rapport avec le cinéma minier des premiers temps [less ▲]

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See detailRéduire l’altérité au travers des processus de traduction et de représentation
Leclercq, Bruno ULg; Smette, Bernard ULg

in Doctorales. Revue LLA-SHS de Montpellier (in press)

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity ... [more ▼]

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity for building equivalences from one language to another through a strategy of reducing the differences in rationality among nations as much as possible. According to Quine, otherness is not insuperable impediment to meeting/encounter and mutual understanding ; by throwing our conceptual schemes on the other communities’ uses/practices – which of course involves some symbolic violence – gaps can always been narrowed. Similarly E. Laclau questions the traditional conception of political representation, which is seen as the transparent process of transmitting someone’s will or interests on another level. For this ideal conception of representation, Laclau substitutes a pragmatic conception which takes in account the irreducible gap between the actors as well as the constitutive opacity of the process of representation : the subject’s will is constituted within the process of representation and through the representative’s productive role. In order to be transposed at the decision-making level, the subject’s interests must be translated by the representative as well as be negotiated with the other represented interests. This implies that the initial will undergoes some identity transformations. [less ▲]

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See detailOn-sky performance of the QACITS pointing control technique with the Keck/NIRC2 vortex coronagraph
Huby, Elsa ULg; Bottom, Michael; Femenia, Bruno et al

in Astronomy and Astrophysics (in press)

A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront ... [more ▼]

A vortex coronagraph is now available for high contrast observations with the Keck/NIRC2 instrument at L band. Reaching the optimal performance of the coronagraph requires fine control of the wavefront incident on the phase mask. In particular, centering errors can lead to significant stellar light leakage that degrades the contrast performance and prevents the observation of faint planetary companions around the observed stars. It is thus critical to correct for the possible slow drift of the star image from the phase mask center, generally due to mechanical flexures induced by temperature and/or gravity field variation, or to misalignment between the optics that rotate in pupil tracking mode. A control loop based on the QACITS algorithm for the vortex coronagraph has thus been developed and deployed for the Keck/NIRC2 instrument. This algorithm executes the entire observing sequence, including the calibration steps, initial centering of the star on the vortex center and stabilisation during the acquisition of science frames. On-sky data show that the QACITS control loop stabilizes the position of the star image down to 2.4 mas rms at a frequency of about 0.02 Hz. However, the accuracy of the estimator is probably limited by a systematic error due to a misalignment of the Lyot stop with respect to the entrance pupil, estimated to be on the order of 4.5 mas. A method to reduce the amplitude of this bias down to 1 mas is proposed. The QACITS control loop has been successfully implemented and provides a robust method to center and stabilize the star image on the vortex mask. In addition, QACITS ensures a repeatable pointing quality and significantly improves the observing efficiency compared to manual operations. It is now routinely used for vortex coronagraph observations at Keck/NIRC2, providing contrast and angular resolution capabilities suited for exoplanet and disk imaging. [less ▲]

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See detailIntravenous lipid emulsions in paediatric patients
Lapillonne, A; Didler Mis, N; Goulet et al

in Clinical Nutrition (in press)

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See detailIPCAPS: an R package for iterative pruning to capture population structure
Chaichoompu, Kridsadakorn ULg; Abegaz Yazew, Fentaw; Tongsima, Sissades et al

in Bioinformatics : Application Notes (in press)

Resolving population genetic structure is challenging, especially when dealing with closely related populations. Although Principal Component Analysis (PCA)-based methods and genomic var- iation with ... [more ▼]

Resolving population genetic structure is challenging, especially when dealing with closely related populations. Although Principal Component Analysis (PCA)-based methods and genomic var- iation with single nucleotide polymorphisms (SNPs) are widely used to describe shared genetic an- cestry, improvements can be made targeting fine-level population structure. This work presents an R package called IPCAPS, which uses SNP information for resolving possibly fine-level population structure. The IPCAPS routines are built on the iterative pruning Principal Component Analysis (ipP- CA) framework to systematically assign individuals to genetically similar subgroups. Our tool is able to detect and eliminate outliers in each iteration to avoid misclassification. It can be extended to de- tect subtle subgrouping in patients as well. In addition, IPCAPS supports different measurement scales for variables used to identify substructure. Hence, panels of gene expression and methylation data can be accommodated. [less ▲]

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See detailTargeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides
Delierneux, Céline ULg; Donis, Nathalie ULg; servais, laurence et al

in Journal of Thrombosis and Haemostasis (in press)

Background: Synthetic phosphorothioate-modified CpG oligodeoxynucleotides (CpG ODNs) display potent immunostimulatory properties that are widely exploited in clinical trials of anticancer treatment ... [more ▼]

Background: Synthetic phosphorothioate-modified CpG oligodeoxynucleotides (CpG ODNs) display potent immunostimulatory properties that are widely exploited in clinical trials of anticancer treatment. Unexpectedly, a recent study indicates that CpG ODNs activate human platelets via the immunoreceptor tyrosine-based activation motif (ITAM)-coupled receptor glycoprotein VI. Objective: To further analyze the mechanisms of CpG ODN-induced platelet activation and identify potential inhibitory strategies. Methods: In vitro analyses were performed on human and mouse platelets, and on cell lines expressing platelet ITAM receptors. CpG ODN platelet activating effects were evaluated in a mouse model of thrombosis. Results: We demonstrated platelet uptake of CpG ODNs, resulting in platelet activation and aggregation. The C-type lectin-like receptor 2 (CLEC-2) expressed in DT40 cells bound CpG ODNs. CpG ODN uptake did not occur in CLEC-2-deficient mouse platelets. Inhibition of human CLEC-2 with a blocking antibody inhibited CpG ODN-induced platelet aggregation. CpG ODNs caused CLEC-2 dimerization, and provoked its internalization. They induced dense granule release before the onset of aggregation. Accordingly, pretreating platelets with apyrase, or inhibiting P2Y12 with cangrelor or clopidogrel prevented CpG ODN platelet activating effect. In vivo, intravenously injected CpG ODN interacted with platelets adhered to mouse injured endothelium, and promoted thrombus growth, which was inhibited by CLEC-2 deficiency or by clopidogrel. Conclusions: CLEC-2 and P2Y12 are required for CpG ODN-induced platelet activation and thrombosis and might be targeted to prevent adverse events in patients at risk. [less ▲]

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See detailAmio Acids in PAediatric Parenteral Nutrition
van Goudoever, J; Carnielli, V; Darmaun, D et al

in Clinical Nutrition (in press)

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See detailIdentification of proteins from wild cardoon flowers (Cynara cardunculus L.) by a proteomic approach
Ben Amira, Amal; Bauwens, Julien ULg; De Pauw, Edwin ULg et al

in Journal of Chemical Biology (in press)

Proteomic approach was applied to identify total proteins, particularly the enzymatic content, from wild cardoon flowers. As the selection of an appropriate sample preparation method is the key for ... [more ▼]

Proteomic approach was applied to identify total proteins, particularly the enzymatic content, from wild cardoon flowers. As the selection of an appropriate sample preparation method is the key for getting reliable results, two different extraction/precipitation methods (trichloroacetic acid and phenol/ammonium acetate) were tested on fresh and lyophilized flowers. After two-dimensional electrophoresis (2D–E) separations, a better protein pattern was obtained after phenol extraction from lyophilized flowers. Only 46 % of the total analyzed spots resulted in a protein identification by mass spectrometry MALDI-TOF. Four proteases (cardosins A, E, G, and H), which have become a subject of great interest in dairy technology, were identified. They presented molecular weights and isoelectric points very close and high levels of homology between matched peptides sequences. The absence of the other cardosins (B, C, D, and F) could be an advantage, as it reduces the excessive proteolytic activity that causes bitter flavors and texture defects, during cheese making. [less ▲]

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See detailLa collaboration entre architectes et plasticiens à Liège dans les années 1930.
Charlier, Sébastien ULg

in In Situ, revue des patrimoines (in press), 26

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales ... [more ▼]

En 1928, des étudiants de l’Académie des Beaux-Arts de Liège fondent la revue d’architecture et d’urbanisme L’Équerre. S’inscrivant bien que tardivement dans la continuité des avant-gardes internationales, le mensuel revendique une vision transversale de l’architecture où la réflexion plastique occupe une place centrale. Dès le départ, elle s’associe à Anthologie, revue imprégnée des théories futuristes et qui diffuse les artistes de l’avant-garde locale. D’abord par le biais de l’édition et des expositions, plasticiens et architectes travaillent ensuite ensemble dans le cadre de projets ambitieux financés par les pouvoirs publics. Cette contribution revient aux racines de cette collaboration en définissant les liens théoriques ou personnels unissant les deux revues. En se concentrant sur les infrastructures publiques, elle comment les artistes et les architectes ont répondu ensemble aux exigences concrètes de la commande en les replaçant dans le contexte social, politique et économique d’une ville belge de seconde importance à la veille de la Seconde Guerre mondiale. [less ▲]

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See detailVaginocutaneous fistula and buttock abscess formation 7 years after polypropylene transobturator tape insertion.
ABDALLAH, Alain; NISOLLE, Michelle ULg; DE LANDSHEERE, Laurent ULg

in Journal de Gynécologie, Obstétrique et Biologie de la Reproduction (in press)

Surgical treatment for stress urinary incontinence (SUI) using transobturator tape insertion is widely accepted. However several postoperative complications were reported in the literature including ... [more ▼]

Surgical treatment for stress urinary incontinence (SUI) using transobturator tape insertion is widely accepted. However several postoperative complications were reported in the literature including infections, abscess and fistula formation. Here we report a case of 57 year old female who presented with abscess and left vaginocutaneous buttock fistula 7 years after transobturator polypropelene tape insertion. Treatment included abscess drainage with dissection of the fistulous tract and removal of the left arm of the transobturator tape along with antibiotic coverage. Sinus drainage stopped after 3 days. Stress urinary incontinence didn't recur. Suspicion of fistula formation should rise in patients presenting with bothersome vaginal or cutaneous discharge after transobturator tape insertion. This case is particular since it describes a fistula complication with polypropelene tape which is unusual with this type of tapes. Treatment of such complication should always consist of surgical removal of the mesh to allow closure of the fistulous tract. [less ▲]

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See detailMulti-temporal monitoring of a regional riparian buffer network (>12,000 km) with LiDAR and photogrammetric point clouds
Michez, Adrien ULg; Piégay, Hervé; Lejeune, Philippe ULg et al

in Journal of Environmental Management (in press)

Riparian buffers are of major concern for land and water resource managers despite their relatively low spatial coverage. In Europe, this concern has been acknowledged by different environmental ... [more ▼]

Riparian buffers are of major concern for land and water resource managers despite their relatively low spatial coverage. In Europe, this concern has been acknowledged by different environmental directives which recommend multi-scale monitoring (from local to regional scales). Remote sensing methods could be a cost-effective alternative to field-based monitoring, to build replicable “wall-to-wall” monitoring strategies of large river networks and associated riparian buffers. The main goal of our study is to extract and analyze various parameters of the riparian buffers of up to 12,000 km of river in southern Belgium (Wallonia) from three-dimensional (3D) point clouds based on LiDAR and photogrammetric surveys to i) map riparian buffers parameters on different scales, ii) interpret the regional patterns of the riparian buffers and iii) propose new riparian buffer management indicators. We propose different strategies to synthesize and visualize relevant information at different spatial scales ranging from local (<10 km) to regional scale (>12,000 km). Our results showed that the selected parameters had a clear regional pattern. The reaches of Ardenne ecoregion have channels with the highest flow widths and shallowest depths. In contrast, the reaches of the Loam ecoregion have the narrowest and deepest flow channels. Regional variability in channel width and depth is used to locate management units potentially affected by human impact. Riparian forest of the Loam ecoregion is characterized by the lowest longitudinal continuity and mean tree height, underlining significant human disturbance. As the availability of 3D point clouds at the regional scale is constantly growing, our study proposes reproducible methods which can be integrated into regional monitoring by land managers. With LiDAR still being relatively expensive to acquire, the use of photogrammetric point clouds combined with LiDAR data is a cost-effective means to update the characterization of the riparian forest conditions. [less ▲]

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See detail"'Les orphelins sur la tombe de leur mère' at the Crossing with Flemish Tradition"
Peere, Isabelle ULg

in B.A.S.I.S - International Ballad Studies (in press)

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis ... [more ▼]

The study proposes a comparative analysis of the French-language and Flemish/Dutch versions of the international ballad deriving from the Danish 'Moderen under Mulde' (Dgf 89), and on this basis identifies three French-language texts recorded in North-east France and Wallonia yet showing closer affinities to the neighbouring Flemish tradition. In the light of both textual traditions, their unilateral adoption of Flemish motifs and their enhancing effect suggests deliberate selection rather than mere geographical proximity or bilingualism as explanation for their hybridization. [less ▲]

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See detailLaBGen: A method based on motion detection for generating the background of a scene
Laugraud, Benjamin ULg; Pierard, Sébastien ULg; Van Droogenbroeck, Marc ULg

in Pattern Recognition Letters (in press)

Given a video sequence acquired with a fixed camera, the generation of the stationary background of the scene is a challenging problem which aims at computing a reference image for a motionless background ... [more ▼]

Given a video sequence acquired with a fixed camera, the generation of the stationary background of the scene is a challenging problem which aims at computing a reference image for a motionless background. For that purpose, we developed our method named LaBGen, which emerged as the best one during the Scene Background Modeling and Initialization (SBMI) workshop organized in 2015, and the IEEE Scene Background Modeling Contest (SBMC) organized in 2016. LaBGen combines a pixel-wise temporal median filter and a patch selection mechanism based on motion detection. To detect motion, a background subtraction algorithm decides, for each frame, which pixels belong to the background. In this paper, we describe the LaBGen method extensively, evaluate it on the SBI 2016 dataset and compare its performance with other background generation methods. We also study its computational complexity, the performance sensitivity with respect to its parameters, and the stability of the predicted background image over time with respect to the chosen background subtraction algorithm. We provide an open source C++ implementation at http://www.telecom.ulg.ac.be/labgen. [less ▲]

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See detailThe clinical relevance of imatinib plasma trough concentrations in chronic myeloid leukemia. A Belgian study
Van Obbergh, F; Knoops, L; Devos, T et al

in Clinical Biochemistry (in press)

This retrospectivemulticenter study in patientswith chronic myeloid leukemia in chronic phasewas undertaken to confirm the clinical relevance of imatinib plasma concentrations monitoring in daily practice ... [more ▼]

This retrospectivemulticenter study in patientswith chronic myeloid leukemia in chronic phasewas undertaken to confirm the clinical relevance of imatinib plasma concentrations monitoring in daily practice. Forty-one patients, with 47 imatinib plasma measurements, were analyzed during treatment with imatinib given at a fixed 400mg daily dose. A significant inverse relationship of imatinib concentration with the patients' weight was observed (Pearson's test: p=0.02,R2=0.1). More interestingly, patientswith poor response (switched to another tyrosine kinase inhibitor because of imatinib failure, or because of disease progression after an initial response) displayed a significantly lower mean imatinib concentration as compared to patients maintained on imatinib (822 ng/mL vs 1099 ng/mL; Student's t-test, p=0.04). Failure or disease progression occurred more often in patients in the lowest quartile of imatinib concentrations compared to patients in the highest quartile (p = 0.02, logrank test). No correlation could be established with other biological or clinical parameter, including complete cytogenic response and majormolecular response. In conclusion: in patients treatedwith imatinib at a fixed daily dose of 400 mg, imatinib plasma concentrations decreased with increasing body weight and were lower in patients switched to another tyrosine kinase inhibitor due to imatinib failure. Systematic determination of imatinib plasma trough levels should be encouraged in such patients. [less ▲]

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See detailRimbaud flâneur
Saint-Amand, Denis ULg

in Francofonia (in press)

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See detailEthnographies du proche: perspectives réflexives et enjeux de terrain
Campigotto, Marie ULg; Dobbels, Rachel ULg; Mescoli, Elsa ULg

in Emulations (in press)

Les contributions de ce volume portent sur différentes expériences d’ethnographie du proche pour montrer en quels termes la réflexivité propre à l’ethnographie se déploie lorsque le contexte au sein ... [more ▼]

Les contributions de ce volume portent sur différentes expériences d’ethnographie du proche pour montrer en quels termes la réflexivité propre à l’ethnographie se déploie lorsque le contexte au sein duquel le chercheur œuvre implique une proximité de différents ordres entre celui-ci et les sujets de son terrain. Elles permettent de répertorier les trajectoires singulières auxquelles le retour réflexif sur l’expérience de terrain peut ouvrir. Trajectoires qui convergent sur certains points et divergent sur d’autres par rapport à la réflexivité qui s’exerce dans le cadre de l’ethnographie telle qu’elle est conçue et pratiquée par l’anthropologue « traditionnel », c’est-à-dire dans ces lieux lointains qui, par définition, installent une distance entre l’observateur et ce(ux) qu’il observe. [less ▲]

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See detailPolyurethane coatings in 20th century outdoor painted sculptures. Part I: Comparative study of various systems by means of ATR-FTIR spectroscopy
Defeyt, Catherine ULg; Langenbacher, Julia; Rivenc, Rachel

in Heritage Science (in press)

Like acrylics and alkyds, polyurethanes (PUs) represent an important class of industrial paints adopted by 20th and 21st artists; primarily by those creating outdoor painted sculptures (OPS). Because PU ... [more ▼]

Like acrylics and alkyds, polyurethanes (PUs) represent an important class of industrial paints adopted by 20th and 21st artists; primarily by those creating outdoor painted sculptures (OPS). Because PU coatings offer a compromise between aesthetic and performance expectations, unachievable with other types of paints, they are commonly recognized as the most appropriate option for painted artworks intended for an outdoor setting. However, the PU class includes various systems and subgroups possessing very different properties. Through the FTIR-ATR study of 137 PU coating references from the Getty Conservation Institute (GCI) reference collection, this paper outlines the differences and the similarities existing, in terms of the composition, of two package solvent-borne, two package water-borne, one package water-borne and fluoropolymer polyurethanes. The comparison of the obtained FTIR-ATR results allowed determining markers helpful to discriminate specific PU subgroups by means of ATR-FTIR spectroscopy. The goals of this paper are to provide to the conservation professionals a better understanding of the versatility and diversity of PU coatings and to facilitate the identification of the various types initially used by the artists. [less ▲]

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See detailElevated carbon dioxide concentration reduces alarm signaling in aphids
Boullis, Antoine ULg; Fassotte, Bérénice ULg; Sarles, Landry ULg et al

in Journal of Chemical Ecology (in press)

Insects often rely on olfaction to communicate with surrounding conspecifics. While the chemical language of insects has been deciphered in recent decades, few studies have assessed how changes in ... [more ▼]

Insects often rely on olfaction to communicate with surrounding conspecifics. While the chemical language of insects has been deciphered in recent decades, few studies have assessed how changes in atmospheric greenhouse gas concentrations will impact pheromonal communication by insects. Here, we hypothesize that changes in the concentration of atmospheric carbon dioxide (CO2) affect the whole dynamics of alarm signaling in aphids, including: (1) the production of the active compound (E)-β-farnesene (Eβf), (2) emission behavior when under attack, (3) perception by the olfactory apparatus, and (4) the escape response. We reared two strains of the pea aphid Acyrthosiphon pisum under ambient and elevated CO2 concentrations for several generations. We found that an increase in CO2 concentration reduced the production (i.e., individual content) and emission of Eβf (released under predation events). While no difference in Eβf neuronal perception was observed, we found that an increase in CO2 strongly reduces the escape behavior expressed by an aphid colony following exposure to natural doses of the alarm pheromone. In conclusion, our results confirm that changes to greenhouse gases do impact chemical communication in insects, and could potentially have a cascade effect on interactions with higher trophic levels. [less ▲]

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See detailPer una edizione integrale e analitica dell'incipit della Storia d'Italia di Francesco Guicciardini
Moreno, Paola ULg

in Laboratoire Italien : Politique et Société (in press)

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See detailTropical moss floras: a homogeneous assemblage of highly mobile species? Insights from their spatial patterns of beta diversity
Norhazrina, N.; Wang, J.; Hagborg, A. et al

in Botanical Journal of the Linnean Society (in press)

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See detailImpact of climate change on potential evapotranspiration under a historical and future climate scenario in the Huang-Huai-Hai Plain, China
Liu, Qin; Yan, Changrong; Ju, Hui et al

in Theoretical & Applied Climatology (in press)

Climate change is widely accepted to be one of the most critical problems faced by the Huang-Huai-Hai Plain (3H Plain), which is a region in which there is an over-exploitation of groundwater region and ... [more ▼]

Climate change is widely accepted to be one of the most critical problems faced by the Huang-Huai-Hai Plain (3H Plain), which is a region in which there is an over-exploitation of groundwater region and where future warmer and drought conditions might intensify crop water demand. In this study, the spatiotemporal patterns of ET0 and primary driving meteorological variables were investigated based on a historical and RCP 8.5 scenario daily data set from 40 weather stations over the 3H Plain using linear regression, spline interpolation method, a partial derivative analysis and multivariate regression. The results indicated a negative trend in all the analysis periods (except spring) of the past 54 years of which only summer and the entire year were statistically significant (p < 0.01) with slopes of -1.09 and -1.30 mm·a-1 respectively. In contrast, a positive trend was observed in all four seasons and the entire year under the RCP 8.5 scenario, with the biggest increment equal to 1.36 mm·a-1 in summer and an annual increment of 3.37 mm·a-1. The spatial patterns of the seasonal and annual ET0 exhibited the lowest values in southeastern regions and the highest values in northeastern parts of Shandong Province, probably because of the combined effects of various meteorological variables over the past 54 years. Relative humidity (RH) together with solar radiation (RS) were detected to be the main climatic factors controlling the reduction of ET0 in summer, autumn, and the entire year on the 3H Plain. ET0 in spring was mainly sensitive to changes in RS and RH, whereas ET0 in winter was most sensitive to changes in wind speed (WS) and decreased due to declining RH. Under the future RCP 8.5 scenario, the annual ET0 distribution displays a rich spatial structure with a clear northeast-west gradient and anarea with low values in the southern regions, which is similarly detected in spring and summer. The most sensitive and primary controlling variables with respect to the increment of future ET0 are in the first place RS and then mean temperature in spring, while turn to be mean temperature and then RS in summer. In autumn, future ET0 is most sensitive to RH changes. WS and RH are the controlling variables for ET0 in winter. Annual future ET0 is most sensitive to RH changes and accordingly RS is responsible for the predicted increment of the annual ET0. Better understanding of current and future spatiotemporal patterns of ET0 and of the regional response of ET0 to climate change can contribute to the establishment of a policy to realize a more efficient use of water resources and a sustainable agricultural production in the 3H Plain. [less ▲]

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See detailRethinking the ‘Case mémorable’ from Pierre Sterckx to Olivier Josso Hamel
Crucifix, Benoît ULg

in European Comic Art (in press), 10(2),

Going back to the origins of the ‘case mémorable’ in the pages of Les Cahiers de la bande dessinée, this article revisits the debates between Pierre Sterckx and Benoît Peeters, articulated around a ... [more ▼]

Going back to the origins of the ‘case mémorable’ in the pages of Les Cahiers de la bande dessinée, this article revisits the debates between Pierre Sterckx and Benoît Peeters, articulated around a conceptual tension between linear and tabular, about the relationship between single panels and narrative. It proposes that the ‘remembered panel’ pinpoints important issues about the recirculation of single images, isolated from their contexts, and the discourse of memory that becomes associated with it. A close-reading of Olivier Josso Hamel’s Au travail, in which the cartoonist redraws his own set of remembered panels, further calls for a reconsideration of Sterckx’s concept in the light of a creative practice that intimately engages with the memory of such panels in a complex relationship to their original narratives. [less ▲]

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See detailA method for independent component graph analysis of resting-state fMRI. Brain and Behavior 2017, in press
Ribeiro de Paula, Demetrius; Ziegler, Erik; Abeyasinghe, P et al

in Brain and Behavior (in press)

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See detailLe cercle de lecture, un dispositif pour construire ensemble des compétences de lecteurs et d'enseignants
Scheepers, Caroline ULg; Outers, Pierre ULg; Werner, Anne-Catherine ULg et al

in Didactiques en Pratique (in press)

Comment accompagner les premiers pas des stagiaires débutants ? À cette vaste et complexe question, le présent article envisage d’apporter un très modeste éclairage. Ainsi, sera décrit, conceptualisé ... [more ▼]

Comment accompagner les premiers pas des stagiaires débutants ? À cette vaste et complexe question, le présent article envisage d’apporter un très modeste éclairage. Ainsi, sera décrit, conceptualisé, analysé et discuté un projet collaboratif qui a associé étroitement théorie et pratique, université et école secondaire, expérimentation et transposition d’un dispositif, didactique disciplinaire et didactique générale. Plus concrètement, il s’est agi de faire expérimenter en tant qu’apprenants un cercle de lecture et un atelier d’écriture par les étudiants romanistes qui suivent le cours de première année de master centré sur la didactique du français langue première, avant de les inviter à transposer l’outil ainsi testé dans leur classe de stage. Seront prises en compte différentes traces : nos consignes, les journaux de stage, les portfolios, les consignes des étudiants, les traces recueillies auprès des élèves du secondaire, les rapports des maitres de stage, etc. Nous verrons in fine que le processus mis en place confirme, toutes proportions gardées, la validité et la pertinence du principe d’homologie entre les activités testées par les stagiaires lors de leur formation initiale à l’université et celles que les formateurs leur recommandent de mettre en œuvre dans leurs classes. [less ▲]

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See detailEarliest Mississippian rugose corals of eastern Australia: post-disaster fauna across the Devonian-Carboniferous Boundary?
Denayer, Julien ULg; Webb, Gregory

in Palaeodiversity & Palaeoenvironments (in press)

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See detailSurface Modification of Powder Metallurgy Titanium by Colloidal Techniques and Diffusion Processes for Biomedical Applications
Ureña, Julia; Mendoza Gallego, Carlos ULg; Ferrari, Begoña et al

in Advanced Engineering Materials (in press)

This contribution focuses on modifying the composition and surface characteristics of powder metallurgy titanium substrates to improve their wear resistance and to reduce the surface Younǵs modulus, while ... [more ▼]

This contribution focuses on modifying the composition and surface characteristics of powder metallurgy titanium substrates to improve their wear resistance and to reduce the surface Younǵs modulus, while maintaining the corrosion resistance and biocompatibility. The modification consists of Mo and TiN coatings produced by colloidal techniques which are deposited by electrophoretic deposition (EPD) or spraying onto green or sintered titanium substrates. The final surface structures are formed during a heat treatment, during which diffusion and consolidation of the layers take place. The surfaces are characterised by XRD, SEM, and micro-indentation; showing diffusion areas of between 40 and 85 microns with clear microstructural changes as well as higher hardness values. [less ▲]

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See detailLes troubles du sommeil chez l'enfant autiste, quel rôle pour le pédopsychiatre?
Abate Ekollo, Joëlle; Malchair, Alain ULg

in Acta Psychiatrica Belgica (in press)

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants ... [more ▼]

Les troubles du sommeil sont fréquents chez l’enfant et leurs origines sont diverses. Ces troubles ont leur ancrage dans le développement neurophysiologique et psychoaffectif de l’enfant. Les enfants souffrant de troubles du spectre autistique présentent un déficit de sommeil, qui peut durer jusqu’à l’adolescence. Les troubles du spectre autistique comportent des comorbidités multiples, dont des altérations du sommeil. Ils sont importants à caractériser dans cette population, car ils peuvent avoir un impact négatif sur les comportements diurnes. Par ailleurs, ils entrainent souvent des difficultés au sein de la famille. La prise en charge doit avant tout prendre en compte le contexte environnemental afin d’améliorer les habitudes et l’hygiène du sommeil. Des questionnaires ainsi que des agendas de sommeil ont été remplis par des parents afin de démontrer l’importance d’une évaluation et d’une prise en compte des troubles du sommeil chez les enfants souffrant d’autisme en consultation pédopsychiatrique. [less ▲]

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See detailMilk-clotting properties of plant rennets and their enzymatic, rheological and sensory role in cheese making: a Review
Ben Amira, Amal; Besbes, Souhail; Attia, Hamadi et al

in International Journal of Food Properties (in press)

Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese ... [more ▼]

Plant rennets hold an important position amongst various coagulants used in cheese technology. The selection of a suitable plant coagulant is important due to the increasing global demands of cheese alongside reduced supply of calf rennet. Thus, a literature synthesis is presented to investigate recent achievements on their functional properties and enzymatic role in cheese making. Efforts have also been done to compare certain rheological and sensory properties of final products, arising from some plant and animal based rennets. In fact, some coagulants such as actinidin or dubiumin produce cheeses with sensory qualities similar to those produced by animal rennet. Others, like ginger, cucumisin or hieronymain proteases contribute to develop very different textures and flavors, due to excessive proteolytic activity and production of bitter peptides. For milk-clotting enzymes with high non-specific action, several improvement strategies have been developed to produce cheeses with sensory properties close to those of animal rennet. For example, the mixture of coagulants (cardosins/chymosin), the selection of appropriate milk or its ultrafiltration, as well as the increase of salting time of cheese during ripening could be efficient ways to improve texture and reduce bitterness. Concerning cheeses with high yield loss, the whey could be used for a traditional production of whey cheese. To conclude, the selection of appropriate plant rennet with high MCA/PA ratio and the optimization of all coagulation parameters play a central role in manufacturing cheese with superior rheological and sensory properties. [less ▲]

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See detailResolved astrometric orbits of ten O-type binaries
Le Bouquin, J.-B.; Sana, H.; Gosset, Eric ULg et al

in Astronomy and Astrophysics (in press)

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2 ... [more ▼]

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2). We follow-up ten O+O binaries with AMBER, PIONIER and GRAVITY at the VLTI. Here, we report about 130 astrometric observations over the last 7 years. We combine this dataset with distance estimates to compute the total mass of the systems. We also compute preliminary individual component masses for the five systems with available SB2 radial velocities. Nine over the ten binaries have their three dimensional orbit well constrained. Four of them are known colliding wind, non-thermal radio emitters, and thus constitute valuable targets for future high angular resolution radio imaging. Two binaries break the correlation between period and eccentricity tentatively observed in previous studies. It suggests either that massive star formation produce a wide range of systems, or that several binary formation mechanisms are at play. Finally, we found that the use of existing SB2 radial velocity amplitudes can lead to unrealistic masses and distances. If not understood, the biases in radial velocity amplitudes will represent an intrinsic limitation for estimating dynamical masses from SB2+interferometry or SB2+Gaia. Nevertheless, our results can be combined with future Gaia astrometry to measure the dynamical masses and distances of the individual components with an accuracy of 5 to 15\%, completely independently of the radial velocities. [less ▲]

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See detailCompte-rendu de l'ouvrage de Boyd Taylor COOLMAN et Dale M. COULTER : Trinity and creation
Close, Florence ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailAssessment of bacterial superficial contamination in classical or ritually slaughtered cattle using metagenetics and microbiological analysis
Korsak Koulagenko, Nicolas ULg; Taminiau, Bernard ULg; Hupperts, Caroline et al

in International Journal of Food Microbiology (in press)

The aim of this study was to investigate the influence of the slaughter technique (Halal vs. Classical slaughter) on the superficial contamination of cattle carcasses, by using traditional microbiological ... [more ▼]

The aim of this study was to investigate the influence of the slaughter technique (Halal vs. Classical slaughter) on the superficial contamination of cattle carcasses, by using traditional microbiological procedures and 16S rDNA metagenetics. The purpose was also to investigate the neck area to identify bacteria originating from the digestive or the respiratory tract. Twenty bovine carcasses (10 from each group) were swabbed at the slaughterhouse, where both slaughtering methods are practiced. Two swabbing areas were chosen: one “legal” zone of 1,600 cm2 (composed of zones from rump, flank, brisket and forelimb) and locally on the neck area (200 cm2). Samples were submitted to classical microbiology for aerobic Total Viable Counts (TVC) at 30°C and Enterobacteriaceae counts, while metagenetic analysis was performed on the same samples. The classical microbiological results revealed no significant differences between both slaughtering practices; with values between 3.95 and 4.87 log CFU/100 cm2 and 0.49 and 1.94 log CFU/100 cm2, for TVC and Enterobacteriaceae respectively. Analysis of pyrosequencing data showed that differences in the bacterial population abundance between slaughtering methods were mainly observed in the “legal” swabbing zone compared to the neck area. Bacterial genera belonging to the Actinobacteria phylum were more abundant in the “legal” swabbing zone in “Halal” samples, while Brevibacterium and Corynebacterium were encountered more in “Halal” samples, in all swabbing areas. This was also the case for Firmicutes bacterial populations (families of Aerococcaceae, Planococcaceae). Except for Planococcoceae, the analysis of Operational Taxonomic Unit (OTU) abundances of bacteria from the digestive or respiratory tract revealed no differences between groups. In conclusion, the slaughtering method does not influence the superficial microbiological pattern in terms of specific microbiological markers of the digestive or respiratory tract. However, precise analysis of taxonomy at the genus level taxonomy highlights differences between swabbing areas. Although not clearly proven in this study, differences in hygiene practices used during both slaughtering protocols could explain the differences in contamination between carcasses from both slaughtering groups. [less ▲]

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See detailHome Parenteral Nutrition in Paediatrics
Hill, S; Ksiaszyk, J; Prell, C et al

in Clinical Nutrition (in press)

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See detailL'enquête sur le fragment apulien Kiev 147 a
Cuvelier, Graham ULg

in Mètis : Revue d'Anthropologie du Monde Grec Ancien : Philologie, Histoire, Archéologie (in press)

Starting with a drawing of the late 19th century, completed by a recent and unpublished picture, this article presents the journey of an Apulian fragment attributed to the circle of the Darius Painter ... [more ▼]

Starting with a drawing of the late 19th century, completed by a recent and unpublished picture, this article presents the journey of an Apulian fragment attributed to the circle of the Darius Painter. This journey is associated with the history of the research related to this fragment, from its discovery in Ruvo in 1869 until its rediscovery in 2000 in Kiev. Then come a description and an iconographic analysis of the scene depicted on it, followed by the interpretations which have been given to it. [less ▲]

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See detailStandard versus individualized parenteral nutrition
Riskin, A; Picaud, J-C; Shamir, R et al

in Clinical Nutrition (in press)

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See detailCrystallization and Gelation Behavior of Low- and High Melting Waxes in Rice Bran Oil: a Case-Study on Berry Wax and Sunflower Wax
Doan, Chi Diem; Tavernier, Iris; Bin Sintang, Mohd Dona et al

in Food Biophysics (in press)

Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the ... [more ▼]

Low-melting berry wax (BEW) has proven to be a good oil gelator with a positive contribution to the consistency and flexibility of the structured oil. Nevertheless, the properties of BEWand the corresponding oleogel have not yet been investigated in-depth. In this research, the difference in crystallization and gelling behavior between sunflower wax (SW), a high melting wax, and BEW, a low-melting wax, in rice bran oil (RBO) was investigated. The difference in melting and crystallization temperatures can be explained by the different chemical composition (long-chain wax esters in SWand shortchain fatty acids in BEW). The heterogeneity in crystal habits (unidirectional platelets versus microcrystalline particles) and polymorphism (orthorhombic versus hexagonal) are responsible for the varying gel strength and hardness of the respective SWand BEW-oleogels. The microcrystalline BEW particles aligned and reorganized during 1-month storage at 5 °C, which leaded to an increase in the gel strength and hardness of BEW-oleogel. The gelling property of SW-oleogel however did not significantly differ after 4 weeks at 5 °C, despite of the appearance of spherulitic crystalline clusters. The changes in the physical properties of wax-based oleogels during storage time were further explored using differential scanning calorimetry, polarized light microscope, powder X-ray diffraction and rheology. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailDiscovery and pharmacological characterization of succinate receptor (SUCNR1/GPR91) agonists
Geubelle, Pierre ULg; Gilissen, Julie; Dilly, Sebastien et al

in British Journal of Pharmacology (in press)

Background and Purpose The succinate receptor (SUCNR1 or GPR91) has been described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho ... [more ▼]

Background and Purpose The succinate receptor (SUCNR1 or GPR91) has been described as a metabolic sensor that may be involved in homeostasis. Notwithstanding its implication in important (patho)physiological processes, the function of SUCNR1 has remained elusive because no pharmacological tools were available. We report on the discovery of the first family of synthetic potent agonists. Experimental Approach We screened a library of succinate analogues and analysed their activity on SUCNR1. In addition, we modelled a pharmacophore and a binding site for the receptor. New agonists were identified based on the information provided by these two approaches. Their activity was studied in various bioassays, including measurement of cAMP levels, [Ca2+]i mobilisation, TGF-α shedding and recruitment of arrestin 3. The in vivo impact of SUCNR1 activation by these new agonists was evaluated on rat blood pressure. Key Results We identified cis-epoxysuccinic acid and cis-1,2-cyclopropanedicarboxylic acid as agonists with an efficacy similar to the one of succinic acid. Interestingly, cis-epoxysuccinic acid was characterized by a 10 to 20 fold higher potency than succinate on the receptor. For example, cis-epoxysuccinic acid reduced cAMP levels with a pEC50 = 5.57 ± 0.02 (EC50 = 2.7 μM) as compared to succinate pEC50 = 4.54 ± 0.08 (EC50 = 29 μM). The rank order of potency of the three agonists was the same in all bioassays tested. In vivo, cis-epoxysuccinic and cis-1,2-cyclopropanedicarboxylic acid increased rat blood pressure to the same extent as succinate did. Conclusions and Implications We provide new agonist tools for SUCNR1 that should facilitate further research on this understudied receptor. [less ▲]

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See detailLa légation des Pays-Bas et de la Franche-Comté en cour de Rome sous Philippe II (1573-1598). Entre limites institutionnelles et efficacité pragmatique
Regibeau, Julien ULg

in Forum Romanum Belgicum (in press)

Dans le dernier quart du XVIe siècle, Philippe II d’Espagne est à la tête de l’ensemble territorial le plus puissant d’Europe. Fils préféré de l’Église romaine et souverain reconnu d’une grande partie de ... [more ▼]

Dans le dernier quart du XVIe siècle, Philippe II d’Espagne est à la tête de l’ensemble territorial le plus puissant d’Europe. Fils préféré de l’Église romaine et souverain reconnu d’une grande partie de l’Italie, il exerce une influence considérable sur la papauté à travers l’action de son ambassadeur espagnol résidant près le Saint-Siège. Ce dernier a pour tâche d’étendre le réseau des alliés au sein de la Curie. Il chapeaute aussi les différents services diplomatiques et ecclésiastiques des États de la monarchie présents dans la cité des papes . Si elle conserve une certaine autonomie, la légation des Pays-Bas et de la Franche-Comté près le Saint-Siège – conduite par l’agent Laurent du Blioul de 1573 à 1598 – est également soumise à la volonté de cet envoyé. Ce n’est d’ailleurs pas un hasard si l’étude de la légation à l’époque du règne de Philippe II a peu passionné les historiens . Effacée derrière la puissance de l’ambassadeur espagnol, celle-ci semble être un piètre avatar des services ecclésiastiques et diplomatiques dépêchés à Rome par les ducs de Bourgogne , Philippe le Beau ou les archiducs Albert et Isabelle . Or, si, aux temps de Laurent du Blioul, la légation, considérée en tant qu’actrice isolée dans le paysage romain, joue un rôle modeste qui se cantonne au suivi des affaires ecclésiastiques provenant des Pays-Bas et de la Franche-Comté, il faut envisager qu’elle fait partie intégrante d’une toile religieuse, diplomatique, sociale et politique plus vaste tissée à Rome par le roi Philippe II et ses agents. Dépassant les seuls intérêts des Pays-Bas, l’étude de cette institution conduit à appréhender tout un pan de la stratégie politique habsbourgeoise. L’imbrication de la légation dans le théâtre diplomatique espagnol à Rome a deux facettes : si, d’une part, elle limite les prérogatives institutionnelles de l’agent du Blioul, d’autre part, elle favorise régulièrement l’efficacité de son action. [less ▲]

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See detailCompte rendu de S. Perceau, O. Szerwiniack (dir.), Polutropia : d’Homère à nos jours (Paris, 2014)
Pitz, Zoé ULg

in Revue de Philologie, de Littérature et d'Histoire Anciennes (in press)

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See detailChronique du colloque international "Médecine et christianisme : sources et pratiques" (Paris, 15-16 septembre 2016)
Carlig, Nathan ULg

in Lettre d'informations du Centre Jean Palerne (in press)

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See detailDe culpable a perseguido: Baudelaire y el proceso de Las Flores del mal
Mogollon Zapata, Juan Manuel ULg

in Revista Historia, Teoría, Crítica (in press)

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo ... [more ▼]

¿Cómo el poeta de Las Flores del Mal paso de ser un autor proscrito, y en consecuencia sospechoso, al autor perseguido e incomprendido que ha inmortalizado la historia literaria? ¿Cómo Baudelaire pudo desviar a su favor una circunstancia que, a primera vista, era desafortunada? Baudelaire supo utilizar el escándalo que provocó la publicación de Las Flores del Mal para promover su figura pública. Un análisis de las posturas discursivas desplegadas por Baudelaire y por sus pares durante y después del proceso nos permitirá comprender mejor la inversión que el poeta hace de su condenación al transformar la sanción penal y moral, y la exclusión a la que ésta conduce, en un signo de su grandeza y de su gloria póstuma. [less ▲]

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See detailDe la quantité de demandeurs d’emploi à la qualité de l’accompagnement. Des professionnels entre « esprit gestionnaire » et relation de service
Remy, Céline ULg; Lavitry, Lynda

in Revue Française de Socio-Economie (in press)

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours ... [more ▼]

L’article explore les liens et les zones de tension entre les politiques de mesure de la performance et la qualité de l’accompagnement à l’emploi telle qu’elle est définie dans les pratiques et discours des agents et prestataires des services publics de l’emploi en France et en Belgique francophone. L’objectif est de démontrer que le pilotage du travail des intermédiaires de l’emploi par les indicateurs de mesure donne lieu à des pratiques, parfois clandestines, de mise en conformité avec le rendement statistique de leur activité. Mais parallèlement, les excès d’une quantification perçue comme abusive ou dangereuse pour leur ethos professionnel poussent une partie d’entre eux à agir en contradiction avec ces principes gestionnaires et ce, au nom de l’intérêt du demandeur d’emploi et de la prise en compte de la qualité des emplois, tendances que l’on décèle dans les deux pays étudiés. [less ▲]

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See detailThe Poetics of (In)visibility: A Stylistic Analysis of Caryl Phillips's Foreigners: Three English Lives
Tunca, Daria ULg

in Ariel : A Review of International English Literature (in press)

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See detailOnderhandelen over vorming van een meerderheid en burgemeester worden in België : Welke invloed heeft de regionale wetgeving ?
Grandjean, Geoffrey ULg

in Chroniques de Droit Public = Publiekrechtelijke Kronieken (in press)

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See detailComprehensive Human Papilloma Virus (HPV) Genotyping in Cervical Squamous Cell Carcinomas and its Relevance to Cervical Cancer Prevention in Malawian Women
Howitt, Brooke; Herfs, Michael ULg; Tomoka, Tamiwe et al

in Journal of Global Oncology (in press)

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See detailChondrocyte secretome: a source of novel insights and exploratory biomarkers of osteoarthritis
Sanchez, Christelle ULg; Bay-Jensen, Anne-Christine; Pap, Thomas et al

in Osteoarthritis and Cartilage (in press)

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See detailTaxonomic significance of variation in sexual condition in Pelekium Mitt. and related genera (Thuidiaceae)
Norhazrina, N.; Patiño, J.; Hedenäs, L. et al

in Journal of Bryology (in press)

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See detailRONALD JENN ET CORINE OSTER (dir.) (2014) : Territoires de la traduction. Artois : Artois Presses Université, 212 p.
Oumarou Mal Mazou, Rachid ULg

in Meta : Journal des Traducteurs = Meta : Translators' Journal (in press)

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See detailRecycling Mitsunobu coupling: a shortcut for troublesome esterifications
Menhour, Boudjema; Obounou Akong, Firmin; Mayon, Patrick et al

in Tetrahedron (in press)

An unusual recycling Mitsunobu reaction proved to be successful to couple two fragments in the course of the synthesis of the hydrophobic moiety of rhamnolipid derivatives. Based on the obtained pivotal ... [more ▼]

An unusual recycling Mitsunobu reaction proved to be successful to couple two fragments in the course of the synthesis of the hydrophobic moiety of rhamnolipid derivatives. Based on the obtained pivotal intermediate, a one pot ‘cross-metathesis/reduction’ approach gave access to structural variations of the side chains. Further study of these molecules will contribute to a better understanding of the role of the lipid moiety in immunostimulatory and plant defense eliciting properties. [less ▲]

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See detailRobbe-Grillet va plus loin avec l'Express... Le romancier face à l'entretien journalistique
Lorent, Fanny ULg

in Interférences Littéraires = Literaire Interferenties (in press)

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See detailImpact of lignin structure on oil production via hydroprocessing with a copperdoped porous metal oxide catalyst
Gillet, sebastien; Petitjean, Laurence; Aguedo, Mario ULg et al

in Bioresource Technology (in press)

A copper-catalyzed depolymerization strategy was employed to investigate the impact of lignin structure on the distribution of hydroprocessing products. Specifically, lignin was extracted from beech wood ... [more ▼]

A copper-catalyzed depolymerization strategy was employed to investigate the impact of lignin structure on the distribution of hydroprocessing products. Specifically, lignin was extracted from beech wood and miscanthus grass. The extracted lignins, as well as a commercial lignin (P1000), were then fractionated using ethyl acetate to provide three different portions for each source of lignin [total of 9 fractions]. Each fraction was structurally characterized and treated with a copper-doped porous metal oxide (Cu-PMO) catalyst under 4 MPa H2 and at 180 °C for 12 hours. The reaction conditions provided notable yields of oil for each fraction of lignin. Analysis of the oils indicated phenolic monomers of commercial interest. The structure of these monomers and the yield of monomer-containing oil was dependent on the origin of the lignin. Our results indicate that hydroprocessing with a Cu-PMO catalyst can selectively provide monomers of commercial interest by careful choice of lignin starting material. [less ▲]

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See detailOf Pins and Beads: Note on a Feminine Costume in Mari
Couturaud, Barbara ULg

in Ash-Sharq (in press), 1

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See detailP.Tebt. 526v: A Land Registry from Tebtunis
Nocchi Macedo, Gabriel ULg; Gilbert, Nathan

in Bulletin of the American Society of Papyrologists (in press)

Edition of a Greek land registry from Tebtunis

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See detailResting-state test–retest reliability of a priori defined canonical networks over different preprocessing steps
Varikuti, Deepthi; Hoffstaedter, Felix; Genon, Sarah ULg et al

in Brain Structure & Function (in press)

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI ... [more ▼]

Resting-state functional connectivity analysis has become a widely used method for the investigation of human brain connectivity and pathology. The measurement of neuronal activity by functional MRI, however, is impeded by various nuisance signals that reduce the stability of functional connectivity. Several methods exist to address this predicament, but little consensus has yet been reached on the most appropriate approach. Given the crucial importance of reliability for the development of clinical applications, we here investigated the effect of various confound removal approaches on the test–retest reliability of functional connectivity estimates in two previously defined functional brain networks. Our results showed that gray matter masking improved the reliability of connectivity estimates, whereas denoising based on principal components analysis reduced it. We additionally observed that refraining from using any correction for global signals provided the best test–retest reliability, but failed to reproduce anti-correlations between what have been previously described as antagonistic networks. This suggests that improved reliability can come at the expense of potentially poorer biological validity. Consistent with this, we observed that reliability was proportional to the retained variance, which presumably included structured noise, such as reliable nuisance signals (for instance, noise induced by cardiac processes). We conclude that compromises are necessary between maximizing test–retest reliability and removing variance that may be attributable to non-neuronal sources. [less ▲]

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See detailFrom thoughts to voices: Understanding the development of auditory hallucinations in schizophrenia
Handest, P; Klimpke, C; Raballo, A et al

in Review of Philosophy and Psychology (in press)

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See detailIsotopic niches of Fin Whales from the Mediterranean Sea and the Celtic sea (North Atlantic)
Das, Krishna ULg; Holleville, Ophélie; Ryan, Conor et al

in Marine Environmental Research (in press)

The fin whale (Balaenoptera physalus) is the most abundant and widespread mysticete species in the Mediterranean Sea, found mostly over deep, offshore waters of the western and central portion of the ... [more ▼]

The fin whale (Balaenoptera physalus) is the most abundant and widespread mysticete species in the Mediterranean Sea, found mostly over deep, offshore waters of the western and central portion of the region. In the Mediterranean, this species is known to feed mainly on krill, in contrast to its Atlantic counterpart, which displays a more diversified diet. The International Whaling Commission recognizes several managements units in the Atlantic and the Mediterranean Sea and the connectivity between these populations is still being debated. Questions remain about inter-individual feeding strategies and trophic ecology. The goal of this study was to compare isotopic niches of fin whales from the Mediterranean Sea and the Celtic Sea (North Atlantic). δ13C and δ15N values were analysed in 136 skin biopsies from free-ranging Mediterranean fin whales sampled in 2010 and 2011 during campaigns at sea. δ13C and δ15N values ranged from -20.4 to -17.1 ‰ and from 5.9 to 8.9 ‰, respectively. These values are in good agreement with those estimated previously from baleen plates from Mediterranean and North Atlantic fin whales. The narrow isotopic niche width of the Mediterranean fin whale (Standard Ellipses area SEAc) compared to the North Atlantic fin whale raises many concerns in the context of global changes and long-term consequences. One could indeed expect that species displaying narrow niches would be more susceptible to ecosystem fragmentation and other anthropogenic impacts. [less ▲]

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See detailOrganisational aspects of paediatric parenteral nutrition
Puntis, J; Hojsak, I; Ksiazyk, J et al

in Clinical Nutrition (in press)

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See detailThe Sense of Taste in Eighteenth-Century France. Flavours of Silence and Words of Perception
Von Hoffmann, Viktoria ULg

in De achttiende eeuw : Documentatieblad van de Werkgroep Achttiende Eeuw (in press), 48(1-2), 13-27

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See detailEccentric training for tendon healing after lesion: a rat model
Kaux, Jean-François ULg; Libertiaux, Vincent ULg; Leprince, Pierre ULg et al

in American Journal of Sports Medicine (in press)

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore ... [more ▼]

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore, eccentric exercise seems to improve the mechanical quality of the tendon. HYPOTHESIS:A combination of PRP injection and eccentric training might be more effective than either treatment alone. STUDY DESIGN:Controlled laboratory study. METHODS:Adult male rats were anesthetized, an incision was performed in the middle of their left patellar tendon and an injection of physiological fluid (PF) or homologous PRP was randomly made at the lesion level. The rats were then divided into 2 groups: the eccentric group, undergoing eccentric training 3 times a week, and the untrained group, without any training. Thus, 4 groups were compared. After 5 weeks, the tendons were removed and their ultimate tensile strength and energy were measured. Tendons were frozen for proteomic analyses when all biomechanical tests were completed. Statistical analysis was performed with linear mixed effect models. RESULTS:No significant difference was found between the treatments using PF injection or PRP injection alone. However, the value of the ultimate tensile force at rupture was increased by 4.5 N (108% of control, P = .006) when eccentric training was performed. An intragroup analysis revealed that eccentric training significantly improved the ultimate force values for the PRP group. Proteomic analysis revealed that eccentric training led to an increase in abundance of several cytoskeletal proteins in the PF group, while a decrease in abundance of enzymes of the glycolytic pathway occurred in the PRP treated groups, indicating that this treatment might redirect the exercise-driven metabolic plasticity of the tendon. CONCLUSION: Eccentric training altered the metabolic plasticity of tendon and led to an improvement of injured tendon resistance regardless of the treatment injected (PF or PRP). CLINICAL RELEVANCE:This study demonstrates the necessity of eccentric rehabilitation and training in cases of tendon lesion regardless of the treatment carried out. [less ▲]

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See detailDécider ensemble ou vivre ensemble. Quelques pas de danse sur un air de tango
Bouhon, Frédéric ULg

in Revue de la Faculté de Droit de l'Université de Liège (in press), 2017/1

Il s'agit de la version publiée de la leçon inaugurale prononcée le 10 novembre 2016.

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See detailExploring Metacognition as Support for Learning Transfer
Scharff, Lauren; Draeger, John; Verpoorten, Dominique ULg et al

in Teaching & Learning Inquiry: The ISSoTL Journal (in press)

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning ... [more ▼]

The ability to transfer learning to new situations lies at the heart of lifelong learning and the employability of university graduates. Because students are often unaware of the importance of learning transfer and staff do not always explicitly articulate this expectation, this article explores the idea that metacognition (intentional awareness and the use of that awareness) might enhance the development of learning transfer. Our exploratory study includes results from a survey of 74 staff and 118 students from five institutions in Australia, Belgium, UK, and USA. Our data indicate that many staff and a majority of students do not have a clear understanding of what learning transfer entails, and that there are many mismatches between staff and student perceptions, attitudes, and behaviors regarding learning transfer. This helps explain why learning transfer does not occur as often as it could. We found significant positive correlations between thinking about transfer and thinking about learning processes and the likelihood to use awareness of metacognition to guide practice. Our findings suggest a positive relationship between metacognition and learning transfer. Implications for scholarship of teaching and learning are discussed. [less ▲]

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See detailComplications of paediatric parenteral nutrition
Decsi, T; Hartman, C; Simchowitz, V et al

in Clinical Nutrition (in press)

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See detailRelating pessimistic memory predictions to Alzheimer’s disease brain structure
Genon, Sarah ULg; Simon, Jessica ULg; Bahri, Mohamed Ali ULg et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (in press)

Patients with Alzheimer’s disease (AD) show impairment of episodic memory and related metacognitive processes. The present study examined subjective metacognitive judgments preceding objective memory ... [more ▼]

Patients with Alzheimer’s disease (AD) show impairment of episodic memory and related metacognitive processes. The present study examined subjective metacognitive judgments preceding objective memory retrieval and investigated the neural correlates of pessimistic predictions for successfully retrieved memories in AD patients. AD patients and healthy older participants provided predictive judgements on their recognition performance before retrieval of famous (semantic) and recently learned (episodic) names. Correlations between grey matter volume (GMV) in T1 images and behavioural scores were examined with multivariate (PLS) and univariate (GLM) analyses in AD patients. AD patients showed a significant proportion of successful name recognition preceded by pessimistic prediction (Prediction_low_hits) in episodic memory. PLS revealed that behavioural pattern in AD patients was related with a mainly right lateralized pattern of GMV decrease including medial temporal lobe and posterior cingulate cortex, but also right ventrolateral prefrontal cortex (VLPFC). GLM further confirmed that pessimistic prediction negatively correlated with GMV in VLPFC. Thus, impaired monitoring processes (possibly influenced by inaccurate beliefs) allowing inferences about one’s own memory performance are primarily related to decrease GMV in VLPFC in AD patients. [less ▲]

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See detailMetals as chemical tracers to discriminate ecological populations of threatened Franciscana dolphins (Pontoporia blainvillei) from Argentina
Romero, M.B.; Polizzi, P.; Chiodi, L. et al

in Environmental Science and Pollution Research (in press)

Franciscana dolphins are the most impacted small cetacean in the Southwestern Atlantic Ocean, classified as Vulnerable A3d by IUCN. Essential (Fe, Mo, Mn, Cr, Ni, Co) and non-essential (Ag, Pb, Sn) trace ... [more ▼]

Franciscana dolphins are the most impacted small cetacean in the Southwestern Atlantic Ocean, classified as Vulnerable A3d by IUCN. Essential (Fe, Mo, Mn, Cr, Ni, Co) and non-essential (Ag, Pb, Sn) trace elements (TEs) were measured in liver, kidney, and brain samples of by-catch Franciscana dolphins that were living in estuarine (n = 21) and marine (n = 21) habitats (1) to assess whether TEs posed a threat and (2) to evaluate the suitability of TEs for discriminating ecological populations of this species in Argentinean waters. Essential TEs showed little variation in tissues from both groups in agreement with levels reported for other cetaceans and suggesting that these concentrations correspond to normal physiological levels. Non-essential TEs were higher in estuarine juveniles and adults dolphins than in marine specimens. These results suggest anthropogenic sources associated with estuarine area and that Franciscana dolphins are good sentinels of the impact of the environment. The difference in the concentrations of TEs beetwen ecological populations appeared to be related to distinct exposures in both geographical areas, and it is suggested that Ag and Sn concentrations in adults are good chemical tracers of anthropogenic input of TEs. These results provide additional information for improved management and regulatory policy. [less ▲]

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See detailVenous Access for Paediatric Parenteral Nutrition
Kolacek, S; Puntis, J; Hojsak, I et al

in Clinical Nutrition (in press)

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See detailUse of a metagenetic approach to monitor the bacterial microbiota of “Tomme d’Orchies” cheese during the ripening process
Ceugniez, Alexandre; Taminiau, Bernard ULg; Coucheney, Françoise et al

in International Journal of Food Microbiology (in press)

The study of microbial ecosystems in artisanal foodstuffs is important to complete in order to unveil its diversity. The number of studies performed on dairy products has increased during the last decade ... [more ▼]

The study of microbial ecosystems in artisanal foodstuffs is important to complete in order to unveil its diversity. The number of studies performed on dairy products has increased during the last decade, particularly those performed on milk and cheese derivative products. In this work, we investigated the bacterial content of "Tomme d'Orchies" cheese, an artisanal pressed and uncooked French cheese. To this end, a metagenetic analysis, using Illumina technology, was utilized on samples taken from the surface and core of the cheese at 0, 1, 3, 14 and 21 days of ripening process. In addition to the classical microbiota found in cheese, various strains likely from environmental origin were identified. A large difference between the surface and the core content was observed within samples withdrawn during the ripening process. The main species encountered in the core of the cheese were Lactococcus spp. and Streptococcus spp., with an inversion of this ratio during the ripening process. Less than 2.5% of the whole population was composed of strains issued from environmental origin, as Lactobacillales, Corynebacterium and Brevibacterium. In the core, about 85% of the microbiota was attributed to the starters used for the cheese making. In turn, the microbiota of the surface contained less than 30% of these starters and interestingly displayed more diversity. The predominant genus was Corynebacterium sp., likely originating from the environment. The less abundant microbiota of the surface was composed of Bifidobacteria, Brevibacterium and Micrococcales. To summarize, the “Tomme d’Orchies” cheese displayed a high diversity of bacterial species, especially on the surface, and this diversity is assumed to arise from the production environment and subsequent ripening process. [less ▲]

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See detailWriting Space in the Plural: New Australian Geographies in Murray Bail's Fiction
Herbillon, Marie ULg

in Journal of the European Association for Studies of Australia (in press), 8

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