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See detailLe Mur et le masque. À propos de Banksy.
Saint-Amand, Denis ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailBrain metabolic dysfunction in Capgras delusion during Alzheimer’s disease: a positron emission tomography study
Jedidi, Haroun ULg; Daury, Noémy; Rémi, Capa et al

in American Journal of Alzheimer's Disease & Other Dementias (in press)

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since ... [more ▼]

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since little is known regarding the neural correlates of Capgras syndrome, the cerebral metabolic pattern of a patient with probable Alzheimer’s disease (AD) and Capgras syndrome was compared with those of 24 healthy elderly subjects and 26 AD patients without delusional syndrome. Compared to the healthy and AD groups, the patient had significant hypometabolism in frontal and posterior midline structures. In light of current neural models of face perception, our patient’s Capgras syndrome may be related to impaired recognition of a familiar face, subserved by the posterior cingulate/precuneus cortex, and impaired reflection about personally relevant knowledge related to a face, subserved by the dorsomedial prefrontal cortex. [less ▲]

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See detailDetermination of arsenic (III) at a nano gold modified solid carbon paste electrode
Sakira, Abdoul Karim; Somé, Issa Touridomon; Ziemons, Eric ULg et al

in Electroanalysis (in press)

A selective and sensitive electroanalytical method was developed for arsenic determination based on a nanogold (AuNP) modified solid carbon paste work- ing electrode (SCPE) modified in two steps (i ... [more ▼]

A selective and sensitive electroanalytical method was developed for arsenic determination based on a nanogold (AuNP) modified solid carbon paste work- ing electrode (SCPE) modified in two steps (i) physisorp- tion and (ii) additional electrodeposition of nanogold par- ticles in the presence of iodide. Copper(II) interference was solved by covering the gold layer by a self assembled mono layer (SAM) of glutathione. Using DPASV a linear response of the signal was obtained as a function of As(III) in the concentration range 0.05–20mM (4– 1498 ppb) with a limit of detection of 0.01 mM (0.9 ppb). Sample stirring and degassing were not needed. Applica- tion to the determination of arsenic(III) and (V) in un- derground water samples from Burkina Faso was success- fully achieved. [less ▲]

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See detailGenetic parameters for mid-infrared methane indicators based on milk fatty acids in dairy cows
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

in Journal of Applied Animal Research (in press)

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not ... [more ▼]

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not currently available. The mid-infrared (MIR) prediction of milk fatty acids is relevant in this context. Five MIR methane indicators were derived from the literature and were calibrated from 600 samples analyzed by gas chromatography. Genetic parameters for these traits were estimated using single trait random regression test-day models from 619,265 records collected from 2007 to 2011 on 71,188 Holstein cows in their first three lactations. For the published indicator showing the highest relationship with the methane data (R2 = 0.88), the average daily heritability was 0.34±0.01, 0.37±0.01 and 0.34±0.01 for the first three lactations, respectively. The methane emission (g/day) was increased from beginning of lactation, reached at the highest in peak of lactation and decreased towards end of lactation. The largest differences between estimated breeding values (EBV) of sires having daughters in production eructing the highest and the lowest methane content was 21.80, 22.75 and 24.89 kg per lactation for the first three parities. Positive genetic correlations were estimated between indicator traits and milk fat and protein content. Low negative correlation was observed with milk yield. In conclusion, this study shows the feasibility to predict methane indicator traits by MIR. Moreover, the estimated genetic parameters suggest also a potential genetic variability of the quantity of methane eructed by dairy cows. [less ▲]

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See detail“How are you Vulnerable?”: Using Participation for Vulnerability Analysis in Emergency Planning
Rossignol, Nicolas ULg; Turcanu, Catrinel; Fallon, Catherine ULg et al

in Journal of Risk Research (in press)

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science ... [more ▼]

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science and Technology Studies (STS) Vulnerability Approach seems very promising. Relying on a constructivist paradigm, it is based on an inductive collection and analysis of a wide range of factors, with a particular focus on cultural factors and actual day-to-day practices. In this paper, we present the roots of this approach and we display findings based on three case studies exploring emergency planning in three different contexts (a city near a SEVESO plant, a school near a nuclear plant, and a city confronted to multiple catastrophic scenarios). The cases studies were realized by conducting three Focus Groups with different types of stakeholders (citizens, teachers, firemen, decision makers, etc.). After presenting the results of the case studies, we discuss how stakeholders’ participation can inform such type of vulnerability analysis in the context of emergency planning. We argue that participation fosters a deep understanding of actual safety governance practices which allows innovative results to emerge as well as it initiates a learning process among the participants. It contributes to questioning the relations between decision-makers, experts and citizens. It has the potential of bypassing the positivist and quantitative rationale of safety, and thus, of redefining the vulnerability governance. As a conclusion, we question the role of such STS vulnerability approach within the actual vulnerability governance. [less ▲]

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See detailDevelopment and validation of the French version of a tool assessing patient's expectations in lower limb osteoarthritis
NEUPREZ, Audrey ULg; Delcour, JP; Fatemi, F et al

in Journal of Orthopaedics (in press)

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See detailLa pollution lumineuse, entre écologie et santé
JEDIDI, Haroun ULg; DEPIERREUX, Frédérique ULg; JEDIDI, Zayd ULg et al

in Revue Médicale de Liège (in press)

Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution ... [more ▼]

Light pollution is defined as the abnormal and disturbing presence of light and its adverse consequences on flora, faunae, ecosystems and its suspected or proven effects on human health. Light pollution is a quite recent and increasing phenomenon within our society and it leads to a major environmental damage, obviously near wildlife, but also on human health (cancers, obesity, fatigue, depression...). The solutions to this problem are however simple, efficient and de facto inexpensive and involving a substantial energy saving. [less ▲]

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See detailDramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Ayora, A F; HERION, Francine ULg; ROMPEN, Eric ULg et al

in Journal of Clinical Periodontology (in press)

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these ... [more ▼]

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients. [less ▲]

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See detailAcyclic, connected and tree sets
Berthé, Valérie; De Felice, Clelia; Dolce, Francesco et al

in Monatshefte für Mathematik (in press)

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See detailExploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for dating
Guibert, Pierre; Urbanova, Petra; Blain, Sophie ULg et al

in Radiation Measurements (in press)

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]

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See detailL'intentionnalité cognitive et ses modes. Reinach critique de Brentano
Dewalque, Arnaud ULg

in Philosophie (in press)

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai ... [more ▼]

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai mon attention sur certaines divergences significatives entre Reinach et Brentano. Après quelques réflexions introductives (§§ 1-2), j’examinerai plus exactement les questions suivantes : quels sont les motifs théoriques qui ont conduit Reinach à s’écarter de la théorie brentanienne du jugement (§§ 3-4) ? Et que retenir de ses analyses aujourd’hui (§§ 5-6) ? [less ▲]

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See detailReduced Order Analysis of Aeroelastic Systems with Freeplay using an Augmented Modal Basis
Silva, Gustavo H. C.; Dal Ben Rossetto, Gustavo; Dimitriadis, Grigorios ULg

in Journal of Aircraft (in press)

Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on ... [more ▼]

Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on the size of the deadband gaps of actuators. In recent years many authors have worked on determining the effects of freeplay on the dynamic behavior of aeroelastic systems; these efforts have yielded significant improvements in the understanding of the phenomena, but have concentrated on simple models. Investigations of industry-relevant aeroelastic models of complete aircraft with freeplay in the actuators have been much rarer, the main difficulty being the selection of an appropriate modal basis that can represent the full range of possible dynamic phenomena. This work presents a novel implementation of the residual vectors approach to create consistent and numerically stable reduced order models suitable for industrial-standard aeroelastic models of aircraft. The methodology relies on the piecewise linear nature of freeplay to create a single reduction basis that represents the dynamics of the system both inside and outside the freeplay deadband gap. The method is demonstrated on an Embraer generic test bench aircraft, showing that the resulting reduced order model is efficient and effective. Nonlinear analysis is carried out using equivalent linearization as well as time integrations of the full nonlinear system. It is shown that, while equivalent linearization is an indispensable tool for a preliminary mapping of the main aeroelastic instabilities, the time integration-based nonlinear analysis is an essential complementary tool to confirm the characteristics of the system behavior. [less ▲]

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See detailFermentation profile of Saccharomyces cerevisiae and Candida tropicalis as starter cultures on barley malt medium
Alloue-Boraud, Mireille; N’Guessan, Kouadio; Djeni, Théodore et al

in Journal of Food Science & Technology (in press)

Saccharomyces cerevisiae C8-5 and Candida tropicalis F0-5 isolated from traditional sorghum beer were tested for kinetic parameters on barley malt extract, YPD (863 medium) and for alcohol production. The ... [more ▼]

Saccharomyces cerevisiae C8-5 and Candida tropicalis F0-5 isolated from traditional sorghum beer were tested for kinetic parameters on barley malt extract, YPD (863 medium) and for alcohol production. The results showed that C. tropicalis has the highest maximum growth rate and the lowest doubling time. Values were 0.22 h-1 and 0.32 h-1 for maximum growth rate, 3 h 09 min and 2 h 09 min for doubling time respectively on barley malt extract and YPD. On contrary, glucose consumption was the fastest with S. cerevisiae (-0.36 g/l/h and -0.722 g/l/h respectively on barley malt extract and YPD). When these two yeasts were used as starters in pure culture and co-culture at proportion of 1:1 and 2:1 (cell/cell) for barley malt extract fermentation, we noticed that maltose content increased first from 12.12 g/l to 13.62-16.46 g/l and then decreased. The highest increase was obtained with starter C. tropicalis + S. cerevisiae 2:1. On contrary, glucose content decreased throughout all the fermentation process. For all the starters used, the major part of the ethanol was produced at 16 h of fermentation. Values obtained in the final beers were 11.4, 11.6, 10.4 and 10.9 g/l for fermentation conducted with S. cerevisiae, C. tropicalis, C. tropicalis + S. cerevisiae 1:1 and C. tropicalis + S. cerevisiae 2:1. Cell viability measurement during the fermentation by using flow cytometry revealed that the lowest mean channel fluorescence for FL3 (yeast rate of death) was obtained with C. tropicalis + S. cerevisiae 2:1 after 48 h of fermentation. [less ▲]

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See detailAn analogue of Cobham's theorem for graph directed iterated function systems
Charlier, Emilie ULg; Leroy, Julien ULg; Rigo, Michel ULg

in Advances in Mathematics (in press)

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See detailAssessment of Toll-like receptor 2, 4 and 9 SNP genotypes in canine sino-nasal aspergillosis
Mercier; Peters, Iain; Farnir, Frédéric ULg et al

in BMC Veterinary Research (in press)

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See detailLe marché des radicaux libres. Sur quelques conditions médiatiques de la posture « néo-réactionnaire ».
Durand, Pascal ULg

in Quaderni : la Revue de la Communication (in press)

L’énorme succès de librairie obtenu par Éric Zemmour avec Le Suicide français, les polémiques ayant entouré l’élection d’Alain Finkielkraut à l’Académie, les mesures prises par un Robert Ménard élu à la ... [more ▼]

L’énorme succès de librairie obtenu par Éric Zemmour avec Le Suicide français, les polémiques ayant entouré l’élection d’Alain Finkielkraut à l’Académie, les mesures prises par un Robert Ménard élu à la mairie de Béziers avec le soutien du FN ou, plus récemment encore, les controverses déclenchées, avant même sa parution, par le sixième roman de Michel Houellebecq (Soumission) viennent de remettre à l’ordre du jour une « querelle » qui, depuis l’Enquête sur les nouveaux réactionnaires publiée par Daniel Lindenberg (2002), n’a cessé de se relancer en des contextes nouveaux. Pour médiocre qu’il soit apparu aux yeux de beaucoup, à commencer par ceux qu’il prenait pour cibles, ce bref essai n’en pointait pas moins quelques problématiques appelées à s’installer durablement sur la scène publique. Au nom d’une lutte contre la « gauche morale » et le « politiquement correct », les charges se sont en effet multipliées jusqu’à nous contre les effets de la « pensée 68 » et de la théorie critique, l’État culturel et la culture de masse, la doxa des droits de l’homme et le libéralisme moral, l’antiracisme et le multiculturalisme, ou bien encore le déclin de l’École et des valeurs républicaines. Forgée sur le modèle des « nouveaux philosophes » et de la « nouvelle droite » des années 1970-1980, l’appellation « nouveaux réactionnaires » procède bien évidemment d’une construction médiatique et polémique, et comme telle paraît bien peu définissable au-delà des coups de force dont elle est le produit autant que le vecteur. Si extensible qu’elle paraisse, et peut-être bien pour cette raison même, elle ne s’est pas moins intégrée, qu’on le veuille ou non, au vocabulaire politique et médiatique courant. Et s'il n’est pas sûr que le phénomène qu'elle recouvre relève à proprement parler d’une histoire des idées, au-delà des controverses idéologiques qui l’ont imposé comme entité collective et qu’il continue de nourrir, ce phénomène n’en constitue pas moins, et à deux titres, un fait identifiable au sein du discours social : en tant qu’il est l’un des produits polémiques de certaines régions de ce discours et en tant qu’il fait bien entendre, dans ce discours, une rhétorique particulière, qui a ses ressorts, ses supports, son histoire. Après avoir pris deux points de vue historiques sur ce phénomène — à longue et courte portée — et évoqué, à la lumière d’une réflexion ouverte par Luc Boltanski et Arnaud Esquerre, ce qui semble le relier à certaines transformations du champ politique de la France des années 2000-2010, l'article met en évidence quelques-unes des transformations de l'espace médiatique et éditorial susceptibles de favoriser sa montée en force dans l'espace public et la capacité qu'ont ses représentants les plus visibles de désigner, au moins nominalement, un certain nombre de problématiques « politiques » et d'urgences « sociales » ou « culturelles » dont il s'agirait de se saisir. [less ▲]

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See detailConditioning materials with biomacromolecules: composition of the adlayer and influence on cleanability
Toure, Yetioman ULg; Genet, J. Michel; Dupont-Gillain, C. Christine et al

in Journal of Colloid and Interface Science (in press)

The influence of substrate hydrophobicity and biomacromolecules (dextran, bovine serum albumin - BSA) adsorption on the cleanability of surfaces soiled by spraying aqueous suspensions of quartz particles ... [more ▼]

The influence of substrate hydrophobicity and biomacromolecules (dextran, bovine serum albumin - BSA) adsorption on the cleanability of surfaces soiled by spraying aqueous suspensions of quartz particles (10 to 30 µm size), then dried, was investigated using glass and polystyrene as substrates. The cleanability was evaluated using radial flow cell (RFC). The surface composition was determined by X-ray photoelectron spectroscopy (XPS). The interpretation of XPS data allowed the complexity due to the ubiquitous presence of organic contaminants to be coped with, and the surface composition to be expressed in terms of both the amount of adlayer and the mass concentration of adlayer constituents. When soiled with a suspension of particles in water, glass was much less cleanable than polystyrene, which was attributed to its much lower water contact angle, in agreement with previous observations on starch soil. Dextran was easily desorbed and did not affect the cleanability. The presence of BSA at the interface strongly improved the cleanability of glass while the contact angle did not change appreciably. In contrast, soiling polystyrene with quartz particles suspended in a BSA solution instead of water did not change markedly the cleanability, while the contact angle was much lower and the aggregates of soiling particles were more flat. These observations are explained by the major role of capillary forces developed upon drying, which influence the closeness of the contact between the soiling particles and the substrate and, thereby, the adherence of particles. The capillary forces are proportional to the liquid surface tension and depend in a more complex way on contact angles of the particles and of the substrate. The dependence of cleanability on capillary forces, and in particular on the liquid surface tension, is predominant as compared with its dependence on the size and shape of the soiling aggregates, which influence the efficiency of shear forces exerted by the flowing water upon cleaning. [less ▲]

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See detailComposantes métacognitives ; Définitions et outils d’évaluation
Frenkel, Stéphanie ULg

in Enfance : Psychologie, Pédagogie, Neuropsychiatrie, Sociologie (in press)

Many tools have been developed since the 1970s in order to assess metacognition and its first implementations. Over time, questionnaires, tests, interviews, observations, computer programmes, and other ... [more ▼]

Many tools have been developed since the 1970s in order to assess metacognition and its first implementations. Over time, questionnaires, tests, interviews, observations, computer programmes, and other methods have become more and more based on self-regulated learning theories. At the same time, for the last fifteen years or so, the number of students with learning difficulties linked to the way they learn seems to be increasing slowly but steadily. Therefore, it seems essential to enable these learners develop a more efficient learning behaviour. Similarly, we see that professional field workers are increasingly asking for efficient and adapted tools in this field. The purpose of this paper is twofold: it provides a review of the above-mentioned assessment tools, and it discusses them in order to contribute to the creation of new tools with a wider scope. Following an analysis of the abundant literature on the subject, two classifications were developed. Thirty-five tools were kept and categorised: first, according to a developmental perspective (preschool, primary school, secondary school and/or adult), second, according to the metacognitive component they assess (metacognitive knowledge, strategies and/or experiences). However, no existing tool covers the whole period of compulsory education. Moreover, in order to assess the learners’ metacognitive abilities fully, it is necessary to combine online and offline assessments in concrete situations. There are still some needs to be met in this regard. [less ▲]

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailInternational assessment of future low flow regimes and their impact on three water related sectors in the Meuse basin – a collaborative approach
Bauwens, Alexandra; Degré, Aurore ULg; Deraedt, Deborah ULg et al

in International Journal of River Basin Management (in press)

There is a wide recognition of the watershed scale as the right scale for global water management, notably in the context of the WFD. Hence, it often refers to international management and therefore to ... [more ▼]

There is a wide recognition of the watershed scale as the right scale for global water management, notably in the context of the WFD. Hence, it often refers to international management and therefore to various pre-existing regional management tools, models or even objectives. In this study we aim at describing the collaborative assessment of climate change’s effect on low flow regime and the consequences on three water related sectors: drinking water production, agriculture and electricity production. The paper highlights the choices that were made during the study that involved scientific teams, managers and stakeholders from the four main countries of the Meuse Basin. It shows that the methodological choices were operational and aimed at preserving existing methods and knowledge within each country. They led to hydrological scenarios comparable to the main available ensemble approaches and to methodologies well accepted within the concerned countries. The results of the project highlight and quantify the water scarcity that the three sectors will have to face by the end of the century mainly regarding the electricity production. They also show that common allocation rules are necessary to manage water demand during future low flow periods. [less ▲]

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See detailRationale for the potential use of mesenchymal stromal cells in liver transplantation
VANDERMEULEN, Morgan ULg; DE ROOVER, Arnaud ULg; BRIQUET, Alexandra ULg et al

in World Journal of Gastroenterology (in press), 20(44), 16418-16432

Mesenchymal stromal cells (MSCs) are multipotent and self-renewing cells that reside essentially in the bone marrow as a non-hematopoietic cell population, but may also be isolated from the connective ... [more ▼]

Mesenchymal stromal cells (MSCs) are multipotent and self-renewing cells that reside essentially in the bone marrow as a non-hematopoietic cell population, but may also be isolated from the connective tissues of most organs. MSCs represent a heterogeneous population of adult, fibroblast-like cells characterized by their ability to differentiate into tissues of mesodermal lineages including adipocytes, chondrocytes and osteocytes. For several years now, MSCs have been evaluated for their in vivo and in vitro immunomodulatory and 'tissue reconstruction' properties, which could make them interesting in various clinical settings, and particularly in organ transplantation. This paper aims to review current knowledge on the properties of MSCs and their use in pre-clinical and clinical studies in solid organ transplantation, and particularly in the field of liver transplantation. The first available clinical data seem to show that MSCs are safe to use, at least in the medium-term, but more time is needed to evaluate the potential adverse effects of long-term use. Many issues must be resolved on the correct use of MSCs. Intensive in vitro and pre-clinical research are the keys to a better understanding of the way that MSCs act, and to eventually lead to clinical success. [less ▲]

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See detailClinical and biological determinants of sclerostin plasma concentration in hemodialysis patients
DELANAYE, Pierre ULg; KRZESINSKI, Jean-Marie ULg; Warling, Xavier et al

in Nephron. Clinical Practice (in press)

Background: Sclerostin is a potent inhibitor of bone formation, but the meaning of its serum levels remains undetermined. We evaluated the association between sclerostin levels and clinical or biological ... [more ▼]

Background: Sclerostin is a potent inhibitor of bone formation, but the meaning of its serum levels remains undetermined. We evaluated the association between sclerostin levels and clinical or biological data in hemodialyzed patients (HD), notably parathormone (PTH), biomarkers of bone turnover, vascular calcifications and mortality after 2 years. Methods: 164 HD patients were included in this observational study. The calcification score was assessed with the Kauppila method. Patients were followed for 2 years. Results: Median sclerostin levels were significantly (p < 0.0001) higher in HD versus healthy subjects (n = 94) (1,375 vs. 565 pg/ml, respectively). In univariate analysis a significant association (p < 0.05) was found between sclerostin and age, height, dialysis vintage, albumin, troponin, homocysteine, PTH, C-terminal telopeptide of collagen type I, bone-specific alkaline phosphatase and osteoprotegerin, but not with the calcification score. In a multivariate model, the association remained with age, height, dialysis vintage, troponin, homocysteine, phosphate, PTH, but also with vascular calcifications. Association was positive for all variables, except PTH and vascular calcifications. The baseline sclerostin concentration was not different in survivors and non-survivors. Conclusions: We confirm a higher concentration of sclerostin in HD patients, a positive association with age and a negative association with PTH. A positive association with phosphate, homocysteine and troponin calls for additional research. The clinical interest of sclerostin to assess vascular calcifications in HD is limited and no association was found between sclerostin and mortality. [less ▲]

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See detailDabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Douxfils, Jonathan; Buckinx, Fanny ULg; Mullier, Francois et al

in Journal of the American Heart Association (in press)

BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of ... [more ▼]

BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of the published literature and a clinical trials registry maintained by the drug manufacturer. Criteria for inclusion in our meta-analysis included all RCTs and the availability of outcome data for MI, other cardiovascular events, major bleeding, and all-cause mortality. Among the 501 unique references identified, 14 RCTs fulfilled the inclusion criteria. Stratification analyses by comparators and doses of dabigatran etexilate were conducted. Peto odds ratio (ORPETO) values using the fixed-effect model (FEM) for MI, other cardiovascular events, major bleeding, and all-cause mortality were 1.34 (95% CI 1.08 to 1.65, P=0.007), 0.93 (95%CI 0.83 to 1.06, P=0.270), 0.88 (95% CI 0.79 to 0.99, P=0.029), and 0.89 (95% CI 0.80 to 1.00, P=0.041). When compared with warfarin, ORPETO values using FEM were 1.41 (95% CI 1.11 to 1.80, P=0.005), 0.94 (95%CI 0.83 to 1.06, P=0.293), 0.85 (95% CI 0.76 to 0.96, P=0.007), and 0.90 (95% CI 0.81 to 1.01, P=0.061), respectively. In RCTs using the 150-mg BID dosage, the ORPETO values using FEM were 1.45 (95% CI 1.11 to 1.91, P=0.007), 0.95 (95% CI 0.82 to 1.09, P=0.423), 0.92 (95% CI 0.81 to 1.05, P=0.228), and 0.88 (95% CI 0.78 to 1.00, P=0.045), respectively. The results of the 110-mg BID dosage were mainly driven by the RE-LY trial. CONCLUSIONS: This meta-analysis provides evidence that dabigatran etexilate is associated with a significantly increased risk of MI. This increased risk should be considered taking into account the overall benefit in terms of major bleeding and all-cause mortality. [less ▲]

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See detailChemical composition of colostrum from Azawak cow in Niger compared with meta-analytical data
Abdou, Harouna; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Animal Genetic Resources Information = Bulletin d'Information sur les Ressources Génétiques Animales = Boletin de Informacion sobre Recursos Geneticos Animales (in press)

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h ... [more ▼]

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h from 7 Azawak cows at calving between August 27, to September 10, 2009 in the Sahel. For data from literature, twenty one (21) references were identified in the following analytical databases: PubMed, Science Direct, Google scholar, Collection from University of Liege. The references were selected according to the following two criteria: i) only studies reported on bovine colostrum were used irrespective of breeds, and ii) among the selected studies, those not providing complete information to allow meta-analytical calculation were excluded. Samples were analyzed for immunoglobulins (IgG, IgM, IgA), lactoferrin, and chemical composition (dry mater, protein, fat, lactose, ash, Ca, P, NA, K, Mg). The mean levels of IgG, IgM, dry matter, protein and fat for Azawak cows were lower (P ˂ 0.001) than those obtained in other breeds; however colostrum from the Azawak was higher in IgA but the difference was not significant. For lactose and ash, mean values for Azawak cows were higher (P ˂ 0.001) than those from the literature. Contents of Ca, P, Na and Mg in Azawak bovine colostrum were significantly higher (P ˂ 0.001) than the mean levels in form the literature data. In conclusion, the colostrum from Azawak cows appears to be lower in most immunoglobulins, in fat and in protein than the values reported in the literature, but higher in lactose and minerals. This could be an adaptation to sahelian contraints. [less ▲]

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See detailBreed-specific hematologic reference intervals in healthy adult Dogue de Bordeaux dogs
Lavoué, Rachel; Geffré, A; Braun, JP et al

in Veterinary Clinical Pathology (in press)

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See detailHow does governmental versus private venture capital backing affect a firm's efficiency? Evidence from Belgium
Alperovych; Hübner, Georges ULg; Lobet, Fabrice

in Journal of Business Venturing (in press)

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We ... [more ▼]

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We find that the government VC-backed firms display significant reductions in productivity. No significant differences in efficiency are found in firms backed by private VC compared with their non-VC-backed peers. Finally, significant reductions in efficiency exist in targets of government VC compared to their non-VC-backed peers. [less ▲]

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See detailModulating effect of COMT Val158Met polymorphism on interference resolution during a working memory task
Jaspar, Mathieu ULg; DIDEBERG, Vinciane ULg; Bours, Vincent ULg et al

in Brain & Cognition (in press)

Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates ... [more ▼]

Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates underlying inhibitory processes and updating in working memory (WM). In an event-related functional magnetic resonance imaging (fMRI) study, we administered a modified version of the Sternberg probe recency task (Sternberg, 1966) to 43 young healthy volunteers, varying the level of interference across successive items. The task was divided into two parts (high vs. low interference) to induce either proactive or reactive control processes. The participants were separated into three groups according to their COMT Val158Met genotype [Val/Val (VV); Val/Met (VM); Met/Met (MM)]. The general aim of the study was to determine whether COMT polymorphism has a modulating effect on the neural substrates of interference resolution during WM processing. Results indicate that interfering trials were associated with greater involvement of frontal cortices (bilateral medial frontal gyrus, left precentral and superior frontal gyri, right inferior frontal gyrus) in VV homozygous subjects (by comparison to Met allele carriers) only in the proactive condition of the task. In addition, analysis of peristimulus haemodynamic responses (PSTH) revealed that the genotype-related difference observed in the left SFG was specifically driven by a larger increase in activity from the storage to the recognition phase of the interfering trials in VV homozygous subjects. These results confirm the impact of COMT genotype on inhibitory processes during a WM task, with an advantage for Met allele carriers. Interestingly, this impact on frontal areas is present only when the level of interference is high, and especially during the transition from storage to recognition in the left superior frontal gyrus. [less ▲]

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See detailBifix codes and interval exchanges
Berthé, Valérie; De Felice, Clelia; Dolce, Francesco et al

in Journal of Pure and Applied Algebra (in press)

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See detailDynamic single-cell analysis of Saccharomyces cerevisiae under process perturbation: comparison of different methods for monitoring the intensity of population heterogeneity
Delvigne, Frank ULg; Baert, Jonathan ULg; Gofflot, Sébastien et al

in Journal of Chemical Technology & Biotechnology (in press)

BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context ... [more ▼]

BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context, microbial phenotypic heterogeneity under bioprocessing conditions needs to be further investigated. In this study, yeast based processes have been investigated by using on-line flow cytometry in combination with a fluorescent transcriptional reporter (GFP) and viability fluorescence tags (propidium iodide, PI). Methods aiming at expressing the dispersion of these fluorescence tags among the yeast populations have been investigated for different bioreactor operating conditions. RESULTS: Yeast viability was determined on the basis of PI uptake. Segregation between PI negative and positive subpopulations could be efficiently quantified on the basis of the mean-to-median ratio or the amplitude of the interquartile range. On the other hand, the same quantification could not be made for the segregation occurring at the level of GFP synthesis. Indeed, when cells were exposed to sub-lethal or mild stresses (such as in scale-down reactors) two GFP subpopulations could be visualized by real-time FC, but quantification by one of the above-mentioned methods was not possible. CONCLUSIONS: Yeast population heterogeneity was observed in representative bioreactor operating conditions. Difficulties for the determination of segregation at the level of GFP synthesis point out the fact that one needs to understand the segregation mechanisms for the applied fluorescent reporters, to judge whether simple mathematical tools may be applied or if more sophisticated computational tools are needed for the quantification of the microbial population segregation. [less ▲]

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See detailConcentration, Activity and Biochemical Characterization of Myeloperoxidase in Fresh and Post-thaw equine semen and their Implication on Freezability
Ponthier, Jérôme ULg; Franck, Thierry ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (in press)

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and ... [more ▼]

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and to correlate these data with motilities in raw and thawed semen. Semen samples from five stallions were collected four times. Motilities were assessed in raw and thawed semen. MPO assays were performed in raw seminal plasma, raw sperm-rich pellet and thawed semen. Total and active MPO concentrations were, respectively, assayed by enzyme-linked immunosorbent assay and specific immunological extraction followed by enzymatic detection. MPO subunits present in semen were characterized by Western 3 blot. Purified active MPO was added in PBS and freezing extender to control its activity during freezing procedure. Differences between medians were determined using Kruskal– Wallis test, and correlations were determined using Spearman’s test for nonparametric data. Active MPO concentration was low in seminal plasma and thawed semen, but high in pellet (p = 0.0058), as the opposite relation was observed for total MPO concentration (p < 0.0001). In seminal plasma and post- thaw semen, inactive 86-kDa MPO precursor was mainly observed. Purified MPO activity was decreased in the extender (p = 0.0286). MPO activity in pellet was highly correlated with thawed progressive motility (r = 􏰑0.5576, p = 0.0086). Inac- tive MPO precursor and unknown low molecular weight inactive MPO precursor subunits explain low MPO activity in semen. Major MPO activity was observed in pellet, and post- thaw loss of activity is partially explained by MPO inactiva- tion in extender. Thawed semen motility was negatively correlated with MPO activity in pellet, becoming a potential freezability predictor. [less ▲]

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See detailInternal encoding style and schizotypy: towards a conceptually-driven account of positive symptoms
Belayachi, Sanaa ULg; Laloyaux, Julien ULg; Laroi, Frank ULg et al

in Journal of Personality Disorders (in press)

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven ... [more ▼]

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven and conceptually-driven processing. A chronic imbalance between these two sources of stimulus encoding is likely to be maladaptive and could underlie cognitive and behavioral disturbances similar to that observed in schizotypy, especially if the balance is tipped too far towards conceptually-driven processing (i.e., Internal encoding style). This study aimed to examine the relationships between encoding style and various dimensions of schizotypy, by using a questionnaire that evaluates the extent to which pre-existing schemata (versus cues from the outside world) affect encoding processes. Consistent with previous findings, our results revealed that both Cognitive-Perceptual and Disorganization dimensions were related to an internal mode of encoding, suggesting that individuals with these features may be characterized by a disposition to biases at early stages of encoding. [less ▲]

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See detailMicrowave-assisted thermochemical and primary hydrolytic conversions of lignocellulosic resources: a review
Richel, Aurore ULg; Jacquet, Nicolas ULg

in Biomass Conversion and Biorefinery (in press)

Faced with the inevitable depletion of fossil resources, agricultural productions have rapidly emerged as promising renewable alternatives. Particularly, the conversion of lignocellulosic materials has ... [more ▼]

Faced with the inevitable depletion of fossil resources, agricultural productions have rapidly emerged as promising renewable alternatives. Particularly, the conversion of lignocellulosic materials has nowadays opened new vistas for the production of energy, biofuels and chemicals. In this literature review, microwave technology is described as an original heating source either for the thermochemical conversions (at temperatures up to 400°C) of lignocellulose into biofuels or the pretreatment (below 400°C) and further hydrolysis of lignocellulose into bioethanol and other valuable chemicals. Advantages of microwave approaches include a commonly observed acceleration in reaction rate and improved selectivities and yields. [less ▲]

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See detailCompte-rendu de l'ouvrage de Pierre RICHÉ, Être enfant au Moyen Âge
Close, Florence ULg

in Moyen Age (Le) (in press)

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See detailNeoformed mineral phases during clay ceramic firing
El Ouahabi, Meriam ULg; Daoudi, Lachen; Hatert, Frédéric ULg et al

in Clays and Clay Minerals (in press)

Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating ... [more ▼]

Ceramic clays are one of the most complicated ceramic systems because of the very complex relationship between the behavior of minerals during the ceramic processing and the transformations during heating. A major challenge is to predict the phase transformations in clay ceramics. The aims are to establish reference data of ceramics products that can be formed based on the mineralogical composition of the local raw materials. These data, in turn, can be compared with the archaeological ceramics in order to study their origins. The mineralogical compositions and transformations during the firing (550 to 1100ºC under oxidizing conditions) of seven clayey materials sampled from the main clay deposits of Northern Morocco were evaluated by X-ray powder diffraction. Two groups of clays were evidenced according to the type of neoformed high-temperature minerals: non-calcareous clays and calcareous clays. For the non-calcareous raw materials, spinel is produced at 950°C. Cristobalite and mullite were formed above 1000ºC from clays that contain illite, kaolinite and chlorite. In clays containing vermiculite and high amount of chlorite, hematite was formed from 950°C. Firing of calcareous clays at temperatures > 950ºC yielded Ca-silicates (diopside, gehlenite and wollastonite), spinel, cristobalite, hematite and feldspars. Mullite may also form in the calcareous clay products, when the carbonates content exceeds 10%. [less ▲]

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See detailA generic anisotropic continuum damage model integration scheme adaptable to both ductile damage and biological damage-like situations
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg

in International Journal of Plasticity (in press)

This paper aims at presenting a general versatile time integration scheme applicable to anisotropic damage coupled to elastoplasticity, considering any damage rate and isotropic hardening formulations ... [more ▼]

This paper aims at presenting a general versatile time integration scheme applicable to anisotropic damage coupled to elastoplasticity, considering any damage rate and isotropic hardening formulations. For this purpose a staggered time integration scheme in a finite strain framework is presented, together with an analytical consistent tangent operator. The only restrictive hypothesis is to work with an undamaged isotropic material, assumed here to follow a J2 plasticity model. The only anisotropy considered is thus a damage-induced anisotropy. The possibility to couple any damage rate law with the present algorithm is illustrated with a classical ductile damage model for aluminium, and a biological damage-like application. The later proposes an original bone remodelling law coupled to trabecular bone plasticity for the simulation of orthodontic tooth movements. All the developments have been considered in the framework of the implicit non-linear finite element code Metafor (developed at the LTAS/MN2L, University of Liège, Belgium - www.metafor.ltas.ulg.ac.be). [less ▲]

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See detailOn the accuracy of adults’ auditory perception of normophonic and dysphonic children’s personality.
Verduyckt, Ingrid; Remacle, Marc; Morsomme, Dominique ULg

in Logopedics, Phoniatrics, Vocology (in press)

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP ... [more ▼]

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP) children and children with VFN (N=10) on the basis of vowels and sentences. The auditory inferred profiles were compared to the actual personality of NP and VFN children. Positive and partly accurate inferences of VFN children’s personality were made on the basis of connected speech, while sustained vowels yielded negative and inaccurate inferences of personality traits of children with VFN. Dysphonic voice quality, as defined by the overall severity of vocal abnormality, conveyed inaccurate and low degrees of Extraversion. This effect was counterbalanced in connected speech by faster speaking rate that accurately conveyed higher degrees of Extraversion, a characteristic trait of VFN children’s actual personality. [less ▲]

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See detailLes défis colossaux auxquels la santé publique va devoir faire face !
COUCKE, Philippe ULg

in Onco : Revue Multidisciplinaire d'Oncologie (in press)

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See detailFernand De Visscher et la Société Internationale d'Histoire des Droits de l'Antiquité
Gerkens, Jean-François ULg

in Revue Historique de Droit Français et Etranger (in press)

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See detailEnzymatic hydrolysis of softwood and hardwood regenerated celluloses
Jacquet, Nicolas ULg; Maniet, Guillaume ULg; Richel, Aurore ULg et al

in Current Chemical Biology (in press)

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for ... [more ▼]

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for hardwood regenerated cellulose (HRC) and 90% for softwood regenerated cellulose (SRC). Crystallinity indices from X-Ray diffraction patterns were used to measure hydrolysis rate of crystalline and amorphous regions. Addition of β-glucosidase to the enzymatic complex of Trichoderma reesei was confirmed to enhance yields of hydrolysis. [less ▲]

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See detailMagie et pharmacopée : l’utilisation des végétaux dans les papyrus iatromagiques grecs
de Haro Sanchez, Magali ULg

in Mythos (in press)

The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For ... [more ▼]

The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For many years, the study of these texts has been part of a research program of the Centre de Documentation de Papyrologie Littéraire (CeDoPaL) of the University of Liège. We will present here the results from the analysis of the content of the prescriptions with plants attested in the Greek iatromagical formularies. [less ▲]

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See detailA European survey on attitudes towards pain and end-of-life issues in locked-in syndrome
Demertzi, Athina ULg; Jox, Ralf J; Racine, Eric et al

in Brain Injury (in press)

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]

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See detailL'espace transitionnel winnicotien et l'_Urraum_ kantien
Seba, Jean-Renaud ULg

in Revista Natureza Humana (in press)

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See detailCritique du capitalisme néolibéral et travail rhétorique chez Frédéric Lordon : un discours d’affectation.
Provenzano, François ULg; Janvier, Antoine ULg

in Dissensus (in press)

Les ouvrages de Frédéric Lordon ont offert ces dernières années un éclairage nouveau des mécanismes de la finance et du capitalisme en régime néolibéral, en vertu de la place centrale qu’ils accordent aux ... [more ▼]

Les ouvrages de Frédéric Lordon ont offert ces dernières années un éclairage nouveau des mécanismes de la finance et du capitalisme en régime néolibéral, en vertu de la place centrale qu’ils accordent aux affects. Il est frappant que cette entreprise – qui est triple: analyse de la finance, analyse du capitalisme, analyse de la domination – soit doublée d’une attention portée au discours même qui la développe. On peut repérer une telle attention dans la pluralité des genres de discours qu’investit Frédéric Lordon : ouvrages « savants » ou « universitaires », mais aussi courts essais engagés aux éditions Raisons d’agir, articles de presse dans Le Monde Diplomatique notamment, tenue du blog « La pompe à phynance » sur le site du même journal, et même pièce de théâtre récemment adaptée au cinéma, D’un retournement l’autre. Comédie sérieuse sur la crise financière. En quatre actes, et en alexandrins . Diversité de genre entre les différents types de textes, donc. Diversité interne à chacun de ces textes, aussi : le lecteur de Frédéric Lordon se trouve toujours à cheval sur plusieurs codes rhétoriques dont joue l’auteur dans un même ouvrage. On pourrait bien sûr tenir cette double diversité pour la simple conséquence du talent d’écriture de Lordon, ou d’un plaisir pris par l’auteur à jouer du langage et des ethos qu’il construit. Le présent article propose au contraire de considérer cette diversité comme le résultat d’un véritable travail sur les modalités rhétoriques du discours critique sur le capitalisme financiarisé, qu’il faut articuler aux principaux postulats de sa théorie sociale. L’hypothèse défendue sera, précisément, de considérer qu’il y a une construction rhétorique qui participe de l’entreprise critique et, du même coup, qui s’inscrit comme un geste politique dans une « société des affects ». [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailDes intentions aux actes : la volition en conseil d'orientation
Broonen, Jean-Paul ULg

in L'Orientation Scolaire et Professionnelle (in press)

A model limited to motivation construct to explain the way from setting a vocational goal to its achievement cannot claim to give an account of how to overcome regulatory problems during goal striving. A ... [more ▼]

A model limited to motivation construct to explain the way from setting a vocational goal to its achievement cannot claim to give an account of how to overcome regulatory problems during goal striving. A model linking volition to motivation is needed. In particular, implementation intentions have been proved to be effective in helping the initiation of goal striving, shielding goal pursuit from unwelcome influences, and disengagement from not successful courses of action. It is proposed to extend the application of this volitional cognitive tool to career counselling. [less ▲]

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See detailExperimental and numerical study of the flight of geese
Dimitriadis, Grigorios ULg; Gardiner, James; Tickle, Peter et al

in Aeronautical Journal (in press)

The flight of barnacle geese at airspeeds representing high-speed migrating flight is investigated using experiments and simulations. The experimental part of the work involved the filming of three ... [more ▼]

The flight of barnacle geese at airspeeds representing high-speed migrating flight is investigated using experiments and simulations. The experimental part of the work involved the filming of three barnacle geese (Branta Leucopsis) flying at different airspeeds in a wind tunnel. The video footage was analysed in order to extract the wing kinematics. Additional information, such as wing geometry and camber was obtained from a 3D scan of a dried wing. An unsteady vortex lattice method was used to simulate the aerodynamics of the measured flapping motion. The simulations were used in order to successfully reproduce the measured body motion and thus obtain estimates of the aerodynamic forces acting on the wings. It was found that the mean of the wing pitch angle variation with time has the most significant effect on lift while the difference in the durations of the upstroke and downstroke has the major effect on thrust. The power consumed by the aerodynamic forces was also estimated; it was found that increases in aerodynamic power correspond very closely to climbing motion and vice versa. Root-mean-square values of the power range from 100 W to 240 W. Finally, it was observed that tandem flying can be very expensive for the trailing bird. [less ▲]

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See detailPLACE DE LA GERIATRIE DANS LA FILIERE DES SOINS
PETERMANS, Jean ULg

in Revue Médicale de Liège (in press)

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See detailCompte-rendu de l'ouvrage de Boyd Taylor COOLMAN et Dale M. COULTER : Trinity and creation
Close, Florence ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailRegards croisés d’orthophonistes : aller/retour entre clinique et recherche
Maillart, Christelle ULg

in ANAE : Approche Neuropsychologique des Apprentissages chez l'Enfant (in press), 131

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See detailDire et décrire le présent dans les lettres de Francesco Guicciardini (1483-1540)
Miesse, Hélène ULg

in Mosaïque (in press)

Depuis les travaux de Jean-Louis FOURNEL et Jean-Claude ZANCARINI, notamment, il est établi que les auteurs florentins qui vécurent à l’époque des guerres d’Italie identifièrent immédiatement la nouveauté ... [more ▼]

Depuis les travaux de Jean-Louis FOURNEL et Jean-Claude ZANCARINI, notamment, il est établi que les auteurs florentins qui vécurent à l’époque des guerres d’Italie identifièrent immédiatement la nouveauté et le caractère extraordinaire des faits qui bouleversèrent leur époque. Parmi ceux-ci, le célèbre Nicolas Machiavel mais aussi son ami et contemporain, Francesco Guicciardini, qui, si l’histoire littéraire ne lui a pas toujours fait la part belle, retrouve ces dernières années la place qui lui revient dans celle des idées. Auteur, historiographe mais aussi lieutenant des troupes pontificales lors de la Ligue de Cognac et, donc, acteur de l’histoire en train de se jouer, Francesco Guicciardini est en prise directe avec les événements ; dans sa volumineuse correspondance se mêlent petite et grande Histoire. Or, si le substantif et l’adjectif « contemporaneo » existent en italien depuis Dante au moins, Guicciardini n’en fait l’usage ni dans ses œuvres, ni dans ses lettres qui ne comptent aucune occurrence du terme. Partant de ce constat, je me propose, dans mon article, de relever et d’analyser le langage utilisé par Guicciardini pour nommer le moment auquel il vit, en cerner les contours et la façon dont celui-ci se distingue de ce qui précède pour former un moment à part : les expressions qui disent le présent (tempo presente/tempi presenti, questi tempi, medesimi tempi) et celles qui le caractérisent (conditione de' tempi, extraordinario, tempi strani) ou qui expriment le moyen de l’affronter (remedii conformi a’ tempi) seront, dès lors, au centre de mon attention. [less ▲]

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See detailMediterranean agri-food processing wastes pyrolysis after pre-treatment and recovery of precursor materials: A TGA-based kinetic modeling study
Manara, Panagiota; Vamvuka, V; Sfakiotakis, S et al

in Food Research International (in press)

Valorization strategies of wastes from agri-food processes are intertwined with clean technological approaches and eco-industrial management. By-products from Mediterranean agri-food processes such as ... [more ▼]

Valorization strategies of wastes from agri-food processes are intertwined with clean technological approaches and eco-industrial management. By-products from Mediterranean agri-food processes such as olive oil, wine and fruit create a considerable disposal problem for the agro-industry. Their characteristics in combination with Mediterranean climate enhance microbial development and can be source of health and safety concerns. After pre-treatment and recovery of valuable precursor materials (lignin, pulp), pyrolysis can be used for fuels, chemicals and carbon bio-based materials production. Since thermal degradation kinetic studies are a key step for the efficient design of thermo-chemical processes, in this study pyrolysis experiments were performed, using TGA for the estimation of the process kinetic parameters. The independent parallel reaction model validat- ed against experimental results, showing a good agreement with experimental data, with deviation values rang- ing from 1.07 to 3.54%. [less ▲]

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See detailVirtual reality as a complementary therapy to sexual addiction treatment
Cismaru Inescu, Adina; Andrianne, Robert ULg; Triffaux, Jean-Marc ULg

in International Journal of Advanced Computer Science (in press), 3(7), 1-5

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See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

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See detailInstitutional Investors, Information Asymmetry, Stock Market Liquidity
Sougné, Danielle ULg; Aymen, Ajina; Faten, Lakhal

in International Journal of Managerial Finance (in press), 11

Purpose. The purpose of this study is to examine the effect of institutional investors ownership and activism on information asymmetry and stock market liquidity in France. Design/methodology/approach ... [more ▼]

Purpose. The purpose of this study is to examine the effect of institutional investors ownership and activism on information asymmetry and stock market liquidity in France. Design/methodology/approach. Our sample includes 162 French-listed firms over a period ranging from 2007 to 2009. Our methodology relies on linear regressions using the method of ordinary least square(OLS). Befor examining the interaction between liquidity and institutional investors, we check for the existence of the endogeneity problem by applying the Durbin-Wu_Hausman test of Davidson and MacKinnon (1993). The results of the endogeneity test show that institutional investor ownership and stock liquidity are endogenous. A simultaneous equation model using the second least square method is then tested to address this problem. Findings The findings show that the proportion of institutional investors has a positive and significant effect on stock-market liquidity, which confirms the signal theory and trading hypothesis. These investors perform high trading activity which favourably affect market liquidity. The results suggests that pension funds manage huge assets decreasing transaction costs and improving liquidity. They display a positive signal to the market about more transparency and a low level of information asymmetry.These results highlight the institutional investors'role in defining the level of liquidity of assets on the French market. Our findings also stress the importance of developing institutional investors'demand for the Paris market in order to better assess firms'values, protect minority ownership and improve market liquidity. Originality/Value In the French institutional setting, institutional investors act as a control device since minority shareholder interests are less protected than in Anglo-American counterparts. This result highlights the significant rôle of institional investors in corporate governance structures and a finacila markets. Their prsence is a guarantee for minority interest protection and for improving market liquidity. [less ▲]

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See detailBiodistribution and radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H: Firstin- human study.
Bretin, Florian ULg; Bahri, Mohamed Ali ULg; BERNARD, Claire ULg et al

in Molecular Imaging & Biology (in press)

Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a ... [more ▼]

Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a distinct but still poorly understood mechanism of action. The objective of this study was to determine the biodistribution and radiation dosimetry of [18F]UCB-H in a human clinical trial and to establish injection limits according to biomedical research guidelines. Additionally, the clinical radiation dosimetry results were compared to estimations in previously published preclinical data. Dynamic whole body PET/CT imaging was performed over approximately 110 minutes on five healthy male volunteers after injection of 144.5 ± 7.1 MBq (range, 139.1 – 156.5 MBq) of [18F]UCB-H. Major organs were delineated on CT images and time-activity curves were obtained from co-registered dynamic PET emission scans. Time-integrated activity coefficients were calculated as area under the curve using trapezoidal numerical integration. Urinary excretion data based on PET-activities including voiding was simulated using the dynamic bladder module of OLINDA/EXM. The radiation dosimetry was calculated using OLINDA/EXM. The effective dose to the OLINDA/EXM 70 kg standard male was 1.54E-02 ± 6.84E-04 mSv/MBq, with urinary bladder wall, gallbladder wall and the liver receiving the highest absorbed dose. The brain, the tracer’s main organ of interest, received an absorbed dose of 1.89E-02 ± 2.32E-03 mGy/MBq. This first human dosimetry study of [18F]UCB-H indicated that the tracer shows similar radiation burdens to widely used common clinical tracers. Single injections of at maximum 672 MBq for USA practice and 649 MBq for European practice keep radiation exposure below recommended limits. Recently published preclinical dosimetry data extrapolated from mice provided satisfactory prediction of total body and effective dose, but showed significant differences in organ absorbed doses compared to human data. [less ▲]

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See detailAnti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease.
Esser, Nathalie ULg; Paquot, Nicolas ULg; Scheen, André ULg

in Expert opinion on investigational drugs (in press)

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease ... [more ▼]

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease (CVD). These observations suggest that pharmacological strategies, which reduce inflammation, may be therapeutically useful in treating obesity, type 2 diabetes and associated CVD. Area covered: The article covers novel strategies, using either small molecules or monoclonal antibodies. These strategies include: approaches targeting IKK-b-NF-kB (salicylates, salsalate), TNF-alpha (etanercept, infliximab, adalimumab), IL-1beta (anakinra, canakinumab) and IL-6 (tocilizumab), AMP-activated protein kinase activators, sirtuin-1 activators, mammalian target of rapamycin inhibitors and C-C motif chemokine receptor 2 antagonists. Expert opinion: The available data supports the concept that targeting inflammation improves insulin sensitivity and beta-cell function; it also ameliorates glucose control in insulin-resistant patients with inflammatory rheumatoid diseases as well in patients with metabolic syndrome or T2DM. Although promising, the observed metabolic effects remain rather modest in most clinical trials. The potential use of combined anti-inflammatory agents targeting both insulin resistance and insulin secretion appears appealing but remains unexplored. Large-scale prospective clinical trials are underway to investigate the safety and efficacy of different anti-inflammatory drugs. Further evidence is needed to support the concept that targeting inflammation pathways may represent a valuable option to tackle the cardiometabolic complications of obesity. [less ▲]

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See detailScience et Dynastie en Belgique : les "conseillers scientifiques" du Roi sous Albert Ier et Léopold III
Pirot, Pascal ULg

in Mosaïque, revue de jeunes chercheurs en SHS – Lille Nord de France – Belgique (in press)

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See detailCompte rendu de D. van Mal-Maeder, A. Burnier, L. Núñez (éds.): Jeux de voix. Énonciation, intertextualité et intentionnalité dans la littérature antique
Macedo, Gabriel ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (in press)

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See detailDefensins: « simple » antimicrobial peptides or broad-spectrum molecules ?
Suarez-Carmona, Meggy ULg; Hubert, Pascale ULg; Delvenne, Philippe ULg et al

in Cytokine & Growth Factor Reviews (in press)

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See detailOutplacement adequacy and benefits: The mediating role of overall justice.
Marzucco, Laurence ULg; Hansez, Isabelle ULg

in Journal of Employment Counseling (in press)

Despite a rapid growth and an ongoing need for outplacement services, little is yet known about the perceived adequacy and benefits of these services for redundant employees using them. We surveyed 360 ... [more ▼]

Despite a rapid growth and an ongoing need for outplacement services, little is yet known about the perceived adequacy and benefits of these services for redundant employees using them. We surveyed 360 Belgian redundant employees (i.e., clients) using outplacement services provided by a public employment agency. The results indicate that an outplacement experience perceived as adequate for clients fosters their overall impressions of justice towards the dismissing organization; this leads in turn to benefits for them: reduction of negative emotions, enhancement of their perceived well-being, future perspectives, and job-seeking activities - confirming the mediating role of overall justice. [less ▲]

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See detailA morphological novelty for feeding and sound production in the yellowtail clownfish
Olivier, Damien ULg; Frederich, Bruno ULg; Herrel, Anthony et al

in Journal of Experimental Zoology. Part A, Comparative Experimental Biology (in press)

The yellowtail clownfish Amphiprion clarkii is able to close its mouth very quickly by means of the cerato-mandibular (c-md) ligament, a synapomorphic trait of Pomacentridae joining the hyoid bar to the ... [more ▼]

The yellowtail clownfish Amphiprion clarkii is able to close its mouth very quickly by means of the cerato-mandibular (c-md) ligament, a synapomorphic trait of Pomacentridae joining the hyoid bar to the medial part of the lower jaw. This fast closure induces tooth collision, thus producing sounds that the clownfish uses during agonistic behaviors. To investigate whether this rapid jaw movement is also used during feeding, we analyzed the kinematics of sound production and feeding. Sound production, feeding on live planktonic prey, and feeding on food attached to tweezers were filmed with a high-speed camera. Three kinds of kinematic patterns were detected and were associated with the two different types of food presented: one performed to catch planktonic prey (PP), and two (called B-1 and B-2) to bite attached food items. The kinematic pattern of B-2 is similar to that observed during sound production (SP) and the transection of the c-md ligament highlights that sound production and biting-2 motions are dependent on this morphological trait. Our data show that the c-md ligament in addition to its role in sound production allows duplication of the mouth closing mechanism during feeding. This highlights the key role played by the c-md ligament in sound production and feeding on attached prey. [less ▲]

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See detailMigration, prostitution and the representation of the black female subject in Nigerian video films about Italy
Jedlowski, Alessandro ULg

in Journal of Italian Cinema and Media Studies (in press)

Much contemporary images of black women in Italian media are marked by the legacy of colonialist propaganda and tend to perpetuate a representation of black women as passive eroticized objects of the ... [more ▼]

Much contemporary images of black women in Italian media are marked by the legacy of colonialist propaganda and tend to perpetuate a representation of black women as passive eroticized objects of the white male gaze. In this sense, Ponzanesi’s call for ‘new and less biased representations, which could help to assess the multiple subject positions that black identities now occupy’ (2005: 179) is still relevant. This article responds to this call by analyzing two Nigerian video films that thematize migration and prostitution trafficking in Italy. By highlighting the complexity of the processes of ‘subjectivation’ taking place throughout the migratory process, these videos invite their viewers to look at the postcolonial subject’s responsibility in shaping the world in which s/he lives, and offer a representation of the black female subject able to go beyond the voyeuristic attitude that characterize much of the existing contemporary Italian visual culture about this topic. [less ▲]

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See detailPractical management of Chronic Myeloid Leukemia in Belgium
Benghiat, FS.; Beguin, Yves ULg; Dessars, B. et al

in Belgian Journal of Hematology (in press)

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]

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See detailRetranslating Cameroon Fulani 'Mbooku' Poems
Oumarou Mal Mazou, Rachid ULg

in Hermeneus : Revista de traducción e interpretación (in press), 17

The article is a retranslation attempt of a Cameroon Fulani 'Mbooku' poem previously transcribed from oral material and translated into English by the Japanese scholar Paul K. Eguchi in 1992. It aims at ... [more ▼]

The article is a retranslation attempt of a Cameroon Fulani 'Mbooku' poem previously transcribed from oral material and translated into English by the Japanese scholar Paul K. Eguchi in 1992. It aims at showing how (re)translation is important for such 'endangered' literature like African oral poems. Moreover, it contributes in introducing primary oral literature to the field of translation studies. [less ▲]

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See detailSurvivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétation
Veymiers, Richard ULg

in Anabases : Traditions et Réception de l'Antiquité (in press)

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See detailLes voyages du goût, entre localité et exotisme.
Mescoli, Elsa ULg

in Anthropology of Food: Fumey, G. ; Jackson, P. et Raffard, P. Culture Alimentaires et Territoires (in press)

« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au ... [more ▼]

« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au travers de ce slogan, un renommé restaurant d’inspiration marocaine de la ville de Milan en Italie, invitait ses clients à voyager au travers de leur sensorialité dans une culture alimentaire (et par synecdoque, une culture tout court) autre. Le goût les aurait amenés à expérimenter un exotisme, qui était néanmoins contrôlé, car certaines conditions imposées par les normes locales faisaient en sorte que le déplacement vécu ne fût pas excessivement déstabilisant. Le résultat de ces négociations consistait d’un menu qui accostait les gastronomies marocaine et italienne (ou les procédures de l’une et de l’autre) dans certains plats décrits comme « fusion », qui satisfaisaient (ou non) les exigences des clients. Dans cet article, je vise à mettre en évidence les mécanismes de production discursive et matérielle de ces plats, ainsi comme les opinions des consommateurs. Pour ce faire, j’analyserai le matériel ethnographique collecté auprès du local en question en le comparant avec les pratiques observés dans d’autres restaurants milanais. En ce qui concerne les effets obtenus, j’appuierait mon analyse sur une plateforme de médias sociaux consacrée aux recensions d’endroits et locaux touristiques. La culture alimentaire sera étudiée dans ses aspects symboliques mais aussi matériels, en faisant également recours au matériel visuel récolté. [less ▲]

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See detailInfluence of process operating conditions on solvent thermal and oxidative degradation in post-combustion CO2 capture
Léonard, Grégoire ULg; Crosset, Cyril; Toye, Dominique ULg et al

in Computers & Chemical Engineering (in press)

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent ... [more ▼]

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data, the kinetics of monoethanolamine degradation is included into a model of the CO2 capture process. The influences of operating conditions and flowsheet improvements on solvent loss and process energy requirement are quantified and validated with pilot plant data. Oxidative degradation in the absorber is identified as the major cause of solvent loss. On the contrary, thermal degradation does not appear as a major concern. Finally, this study leads to a decrease by 10% of the process exergy requirement along with a reduction by 11% of the solvent loss, all that by using a single model. Thus, this model provides a practical tool to minimize both the energy requirement and the solvent degradation by the design of large-scale CO2 capture units. [less ▲]

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See detailLa maladie de Lyme entre cadrage infectieux, vectoriel et zoonotique : vers une écologisation des problèmes sanitaires
Massart, Clémence

in VertigO : la Revue Electronique en Sciences de l'Environnement (in press)

This paper is devoted to the qualification of Lyme disease in France. Firt vectorial disease in the northern hemisphere, Lyme diseas is transmitted by a genus of tick called Ixodes (in Europe by Ixodes ... [more ▼]

This paper is devoted to the qualification of Lyme disease in France. Firt vectorial disease in the northern hemisphere, Lyme diseas is transmitted by a genus of tick called Ixodes (in Europe by Ixodes ricinus ; in Asia by Ixodes persulcatus ; in United States and in Canada by Ixodes scapularis). Concerned only with human health and limited to Lyme, a first framing has grown around physicians and patients which are involved in a controversy. Progressively, a second framing has emerged, called vectorial and structured around ecologists, normally not involved in human health. Based on the vector, this framing includes other diseases transmitted by Ixodes ricinus which, during the last 30 years, have been discovered : Tick-Borne Encephalitis, Babesia divergens, Bartonella infection, Tularemia, etc. Linked to these new pathologies, the media coverage of Lyme has finally opened the « vectorial transmission category » – usually associated to mosquitoes and south countries – to ticks and diseases from the north. A third framing dedicated to animal reservoir and called zoonotic is emerging at last. We can see in that framing overlapping a kind of “ecologization” of sanitary issues. [less ▲]

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See detailBrazil – EU Partnership: from high expectations to limited results
Santander, Sébastian ULg; Saraiva, Miriam

in European Journal of International Relations (in press)

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See detailEvaluation of the impact of 6-month training by whole body vibration on the risk of falls among nursing home residents, observed over a 12-month period: a single blind, randomized controlled trial.
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Maquet, Didier ULg et al

in Aging Clinical & Experimental Research (in press)

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement ... [more ▼]

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. OBJECTIVE: The objective of the present study was to evaluate the impact of 6-month training by WBV on functional and motor abilities among nursing home residents observed over a 12-month period. METHODS: Patients were randomized into two groups: the WBV group which received three training sessions every week composed of five series of 15 s of vibration at 30 Hz intensity for a period of 6 months and a control group with normal daily life. The impact of this training on the risk of falls was assessed blindly after 6 and 12 months by the Tinetti Test, the "Timed Up and Go" test and a quantitative evaluation of a 10-s walk performed with a tri-axial accelerometer. The occurrence of falls was also observed. RESULTS: 62 elderly healthy volunteers, (47 women and 15 men, mean age 83.2 +/- 7.9 years) were included in this study. There was no significant difference between the two groups regarding the Tinetti test (p = 0.75), the "Timed Up and Go" test (p = 0.19) and the Locometrix(R) test, except for the step length, measured by dual task (p < 0.01). No significant inter-group difference in the frequency of falls was observed during the 12 months of research. A total of 42 falls were recorded during the first 6 months of experimentation: 24 falls in the treated group and 18 in the control group (p = 0.60). During the next 6 months, 19 falls occurred: 8 falls in the treated group and 11 in the control group (p = 0.52). CONCLUSION: This study failed to establish the effectiveness of low doses of WBV, under the conditions used in our study, on functional and motor abilities of institutionalized elderly patients. However, given the positive results of other studies, further investigations, with modified therapeutic protocols, seem necessary to clarify the effects of WBV in the elderly. [less ▲]

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See detailSmall Angle X-ray Scattering Insights into the Architecture-Dependent Emulsifying Properties of Amphiphilic Copolymers in Supercritical Carbon Dioxide
Alaimo, David ULg; Hermida Merino, Daniel; Grignard, Bruno ULg et al

in Journal of Physical Chemistry B (in press)

The supramolecular assembly of a series of copolymers combining a PEO-rich hydrophilic and fluorinated CO2-philic sequences is analysed by synchrotron small-angle xray scattering (SAXS) in supercritical ... [more ▼]

The supramolecular assembly of a series of copolymers combining a PEO-rich hydrophilic and fluorinated CO2-philic sequences is analysed by synchrotron small-angle xray scattering (SAXS) in supercritical CO2, as well as in water/CO2 emulsions. These copolymers were designed to have the same molecular weight and composition, and to differ only by their macromolecular architecture. The investigated copolymers have random, block, and palm-tree architectures. Besides, thermo-responsive copolymer is also analysed, having a hydrophilic sequence becoming water-insoluble around 41 °C, i.e. just above the critical point of CO2. At the length scale investigated by SAXS, only the random copolymer appears to self-assemble in pure CO2, in the form of a disordered microgel-like network. The random, block and thermo-responsive copolymers are all able to stabilize water/CO2 emulsions but not the copolymer with the palm-tree architecture, pointing at the importance of macromolecular architecture for the emulsifying properties. A modelling of the SAXS data shows that the block and the thermo-responsive copolymers form spherical micelle-like structures containing about 70 % water and 30 % polymer. [less ▲]

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See detailDUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis
Musumeci, Lucia ULg; Kuijpers, Marijke; Gilio, Karen et al

in Circulation (in press)

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet ... [more ▼]

Background A limitation of current antiplatelet therapies is their inability to separate thrombotic events from bleeding occurrences. Better understanding of the molecular mechanisms leading to platelet activation is of importance for the development of improved therapies. Recently, protein tyrosine phosphatases (PTPs) have emerged as critical regulators of platelet function. Methods and Results This is the first report implicating the dual-specificity phosphatase 3 (DUSP3) in platelet signaling and thrombosis. This phosphatase is highly expressed in human and mouse platelets. Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion mediated through the collagen receptor glycoprotein VI (GPVI) and the C-type lectin-like receptor 2 (CLEC-2). DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism, compared to wild-type mice, and showed severely impaired thrombus formation upon ferric chloride-induced carotid artery injury. Intriguingly, bleeding times were not altered in DUSP3-deficient mice. At the molecular level, DUSP3 deficiency impaired Syk tyrosine phosphorylation, subsequently reducing phosphorylation of PLCγ2 and calcium fluxes. To investigate DUSP3 function in human platelets, a novel small-molecule inhibitor of DUSP3 was developed. This compound specifically inhibited collagen and CLEC-2-induced human platelet aggregation, thereby phenocopying the effect of DUSP3 deficiency in murine cells. Conclusions DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo. Inhibition of DUSP3 may prove therapeutic for arterial thrombosis. This is the first time a PTP, implicated in platelet signaling, has been targeted with a small-molecule drug. [less ▲]

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See detailDe Jacques Antoine aux Eperonniers : l'édition littéraire en Belgique au passé et au présent (seconde partie)
Durand, Pascal ULg; Habrand, Tanguy ULg

in Textyles : Revue des Lettres Belges de Langue Française (in press)

Second volet d'un article en deux parties portant sur l'édition littéraire contemporaine en Belgique, autour de deux maisons importantes : les éditions Jacques Antoine et les éditions des Eperonniers. La ... [more ▼]

Second volet d'un article en deux parties portant sur l'édition littéraire contemporaine en Belgique, autour de deux maisons importantes : les éditions Jacques Antoine et les éditions des Eperonniers. La seconde partie de cette étude porte plus précisément sur la transition d'une maison à l'autre et sur la politique de la création contemporaine suivie par Lysiane d'Hayere aux Eperonniers. [less ▲]

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See detailClinical pattern characterisation of cattle naturally infected by BTV-8 - Clinical characterisation of BTV-8 infected cattle
Zanella, G; Martinelle, Ludovic ULg; Guyot, Hugues ULg et al

in Transboundary and Emerging Diseases (in press)

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See detailAllogeneic hematopoietic stem cell transplantation in solid organ transplant recipients: a retrospective, multicenter study of the EBMT
Basak, GW.; Wiktor-Jedrzejczak, W.; Labopin, M. et al

in American Journal of Transplantation (in press)

We conducted a questionnaire survey of the 565 European Society for Blood and Marrow Transplantation centers to analyze the outcome of allogeneic hematopoietic stem cell transplantation (alloSCT) in ... [more ▼]

We conducted a questionnaire survey of the 565 European Society for Blood and Marrow Transplantation centers to analyze the outcome of allogeneic hematopoietic stem cell transplantation (alloSCT) in recipients of solid organ transplantation (SOT). We investigated 28 patients with malignant (N=22) or nonmalignant diseases (N=6), who underwent 31 alloSCT procedures: 12 after kidney, 13 after liver, and three after heart transplantation. The incidence of solid organ graft failure at 60 months after first alloSCT was 33% (95% confidence interval [CI], 16–51%) for all patients, 15% (95% CI, 2–40%) for liver recipients, and 50% (95% CI, 19–75%) for kidney recipients (p = 0.06). The relapse rate after alloSCT (22%) was low following transplantation for malignant disorders, despite advanced stages of malignancy. Overall survival at 60 months after first alloSCT was 40% (95% CI, 19–60%) for all patients, 51% (95% CI, 16–86%) for liver recipients, and 42% (95% CI, 14–70%) for kidney recipients (p = 0.39). In summary, we show that selected SOT recipients suffering from hematologic disorders may benefit from alloSCT and experience enhanced long-term survival without loss of organ function. [less ▲]

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See detailDépister la fragilité, un bénéfice pour le patient et pour le soignant
RICOUR, Céline ULg; DESAINTHUBERT, Marie; GILLAIN, Sophie ULg et al

in Revue Médicale de Liège (in press)

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See detailCompte rendu de l'ouvrage de Frédéric MARCHESANI, Sur les traces des anciens "pays" de Wallonie
George, Philippe ULg

in Trésor de Liège. Bulletin trimestriel (in press)

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See detailIsland floras are not necessarily more species-poor than continental ones.
Patiño, J.; Solymos, P.; Carine, M.A. et al

in Journal of Biogeography (in press)

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See detailInvestigating word recognition in intercomprehension: methods and findings
Möller, Robert ULg; Zeevaert, Ludger ULg

in Linguistics (in press), 53(2),

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See detailRevisiting the SN1987A gamma-ray limit on ultralight axion-like particles
Payez, Alexandre ULg; Evoli, Carmelo; Fischer, Tobias et al

in Journal of Cosmology and Astroparticle Physics [= JCAP] (in press)

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and ... [more ▼]

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and eventually convert into gamma rays in the magnetic field of the Milky Way. The lack of a gamma-ray signal in the GRS instrument of the SMM satellite in coincidence with the observation of the neutrinos emitted from SN1987A therefore provides a strong bound on their coupling to photons. Due to the large uncertainty associated with the current bound, we revise this argument, based on state-of-the-art physical inputs both for the supernova models and for the Milky-Way magnetic field. Furthermore, we provide major amendments, such as the consistent treatment of nucleon-degeneracy effects and of the reduction of the nuclear masses in the hot and dense nuclear medium of the supernova. With these improvements, we obtain a new upper limit on the photon-ALP coupling: g_{a\gamma} < 5.3 x 10^{-12} GeV^{-1}, for m_a < 4.4 x 10^{-10} eV, and we also give its dependence at larger ALP masses. Moreover, we discuss how much the Fermi-LAT satellite experiment could improve this bound, should a close-enough supernova explode in the near future. [less ▲]

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See detailMontage et résistance du réel chez S. Kracauer: Photographie, cinéma, texte.
Hagelstein, Maud ULg; Hamers, Jérémy ULg

in Bulletin d'Analyse Phénoménologique (in press)

Partant de quelques textes dans lesquels S. Kracauer traite du rapport entre montage et réel, cet article tente de préciser et de problématiser l’ambivalence de Kracauer à l’égard de l’outil « montage » ... [more ▼]

Partant de quelques textes dans lesquels S. Kracauer traite du rapport entre montage et réel, cet article tente de préciser et de problématiser l’ambivalence de Kracauer à l’égard de l’outil « montage », notamment dans le champ cinématographique, en ouvrant la réflexion par cette double question : comment définir un « mauvais usage » du montage et, à l’opposé, comment peuvent se mettre en place les conditions d’un « bon usage » du montage selon Kracauer ? Pour y répondre, les auteurs identifient d'abord, dans l’œuvre de Kracauer, les éléments explicites et implicites (montage textuel) qui permettent de saisir au plus près ce que serait, selon le philosophe et sociologue, le principe de réalité. Ensuite, une œuvre photographique, contemporaine des quelques textes évoqués, Menschen des 20. Jahrhunderts d’August Sander, permet de mieux circonscrire les possibles concrétisations de cette pensée en la mettant à l’épreuve d’une réalisation en images et en montage. [less ▲]

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See detailAn XFEM/CZM implementation for massively parallel simulations of composites fracture
Vigueras, Guillermo; Sket, Federico; Samaniego, Cristobal et al

in Composite Structures (in press)

Because of their widely spread use in many industries, composites are the subject of many research campaigns. More particularly, the development of both accurate and flexible numerical models able to ... [more ▼]

Because of their widely spread use in many industries, composites are the subject of many research campaigns. More particularly, the development of both accurate and flexible numerical models able to capture their intrinsically multiscale modes of failure is still a challenge. The standard finite element method typically requires intensive remeshing to adequately capture the geometry of the cracks and high accuracy is thus often sacrificed in favor of scalability, and vice versa. In an effort to preserve both properties, we present here an extended finite element method (XFEM) for large scale composite fracture simulations. In this formulation, the standard FEM formulation is partially enriched by use of shifted Heaviside functions with special attention paid to the scalability of the scheme. This enrichment technique offers several benefits, since the interpolation property of the standard shape function still holds at the nodes. Those benefits include (i) no extra boundary condition for the enrichment degree of freedom, and (ii) no need for transition/blending regions; both of which contribute to maintain the scalability of the code. Two different cohesive zone models (CZM) are then adopted to capture the physics of the crack propagation mechanisms. At the intralaminar level, an extrinsic CZM embedded in the XFEM formulation is used. At the interlaminar level, an intrinsic CZM is adopted for predicting the failure. The overall framework is implemented in ALYA, a mechanics code specifically developed for large scale, massively parallel simulations of coupled multi-physics problems. The implementation of both intrinsic and extrinsic CZM models within the code is such that it conserves the extremely efficient scalability of ALYA while providing accurate physical simulations of computationally expensive phenomena. The strong scalability provided by the proposed implementation is demonstrated. The model is ultimately validated against a full experimental campaign of loading tests and X-ray tomography analyses for a chosen very large scale. [less ▲]

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See detailL'atlas à l'épreuve de l'image en mouvement (Warburg, Farocki, Didi-Huberman)
Hagelstein, Maud ULg; Hamers, Jérémy ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Partant des travaux récents de Georges Didi-Huberman sur l’atlas d’images (A. Warburg) comme outil et support d’une nouvelle heuristique du montage, ce texte confronte l’installation Histoires de fantômes ... [more ▼]

Partant des travaux récents de Georges Didi-Huberman sur l’atlas d’images (A. Warburg) comme outil et support d’une nouvelle heuristique du montage, ce texte confronte l’installation Histoires de fantômes pour grandes personnes (G. Didi-Huberman, A. Gisinger, 2012), composée pour partie d’images en mouvement, à la pensée de la table warburgienne comme lieu d’une perpétuelle reconfiguration et d’une nouvelle lisibilité du monde. Se pourrait-il en effet qu’une image en mouvement, prise d’ordinaire dans un continuum clos, se dote, à travers le montage, des mêmes potentialités critiques – c’est-à-dire d’un même pouvoir inquiétant – que l’image fixe offerte au déambulateur de l’atlas ? [less ▲]

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See detailLe pouvoir par les armes, le pouvoir par les idées
Dumont, Jonathan ULg; Masson, Christophe ULg

in Moyen Age (Le) (in press), 120(3-4),

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