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See detailÉVOLUTION DE LA TENEUR EN EAU LE LONG D’UNE TOPOSEQUENCE FORESTIERE ARGILO-LIMONEUSE
Deraedt, Deborah ULg; Colinet, Gilles ULg; Degré, Aurore ULg

in Milieux Poreux et Transferts Hydriques (in press)

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and ... [more ▼]

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and steep slope. The soil water content is monitored at several positions on the toposequence and at different depth. During rain events, peak in soil water content are observed in different depth depending on the position along the toposequence. [less ▲]

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See detailMesurer les distances entre des textes pré-carolingiens linguistiquement non-normés: le cas de la Passion de sainte Marine
Goullet, Monique; Philippart de Foy, Caroline ULg

in Etudes Classiques (Namur, Belgium) (in press)

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See detailLes modes d'acquisition et de transmission du savoir médical dans l'antiquité gréco-romaine
Marganne, Marie-Hélène ULg

in Histoire des Sciences Médicales (in press)

This paper aims to define and describe the ways of acquiring and transmitting medical knowledge in Greco-Roman Antiquity through an analysis of literary, archaeological, and, primarily, papyrological ... [more ▼]

This paper aims to define and describe the ways of acquiring and transmitting medical knowledge in Greco-Roman Antiquity through an analysis of literary, archaeological, and, primarily, papyrological sources. The methods and practices revealed by these sources include experiment, analogy, and imitation, oral and written teaching, the composition and copying of books (illustrated or not), as well as the elaboration of commentaries, abridgments, questionnaires, and word lists. These modes of knowledge transfer were intended not only for medical practitioners and students, but also for philiatroi, for generally educated people, as well as for scribes, and eventually tachygraphers, of medical books. [less ▲]

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See detailTwo-loop-induced neutrino masses: A model-independent perspective
Aristizabal Sierra, Diego ULg

in PoS - Proceedings of Science (in press)

We disucuss Majorana neutrino mass generation mechanisms at the two-loop order. After briefly reviewing the systematic classification of one-loop realizations, we then focus on a general two-loop ... [more ▼]

We disucuss Majorana neutrino mass generation mechanisms at the two-loop order. After briefly reviewing the systematic classification of one-loop realizations, we then focus on a general two-loop classification scheme which provides a model-independent catalog for neutrino mass models at the two-loop order [less ▲]

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See detailPaper Formats of the Mamluk Period: The Contribution of Mamluk Chancery Paper
Bauden, Frédéric ULg

in Journal of Islamic Manuscripts (in press)

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See detailEncounters of the third kind: antonyms and tertium
Steffens, Marie ULg

in Studies van de BKL - Travaux du CBL - Papers of the LSB (in press)

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See detailArrêt(s) sur image(s) : usages et pratiques du photogramme
Thonon, Jonathan ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailBiolaw and dual use dilemma: the freedom of scientific research in relationship with traditional and emerging sciences and technologies
Colussi, Ilaria Anna ULg

in International Journal of Biolaw (in press)

Science and technology require an intervention by the law, and law is called upon to intervene in front of their evolution, and to look for proper solutions of governance and rational responses to their ... [more ▼]

Science and technology require an intervention by the law, and law is called upon to intervene in front of their evolution, and to look for proper solutions of governance and rational responses to their risks. One of the main issues to be investigated from the legal viewpoint is represented by the ‘dual-use dilemma’ that arises both in ‘traditional’ and new areas of techno-sciences. Indeed, any kind of research has the potential to be used both for bad as well as for good purposes. Therefore, it is important to reflect upon the ways to control possibly dangerous research without preventing the progress from going further. Such ‘dual-use dilemma’, then, entails the study of one of the fundamental freedoms in the biolaw area: the freedom of scientific research, its limits, and relationship with other rights/needs/freedoms (such the need of security). This work focuses on two areas of the techno-scientific world. One is more ‘traditional’, i.e. nuclear science, in whose context the reflections on ‘dual-use’ were born and developed, and the other one is a new emerging technology, which is synthetic biology. The aim is to understand how the freedom of scientific research could be shaped in relationship with other rights/needs/interests for dealing with ‘dual-use’ issues in the aforementioned areas of science and technology. [less ▲]

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See detailQuatre configurations pour créer une dynamique interactive entre formation et recherche Expériences dans le domaine de la formation des professionnels de la santé
Faulx, Daniel ULg; Burlet, Géraldine ULg; Bernard, Nicolas ULg et al

in Recherches Qualitatives (in press)

Dans cette contribution, nous nous penchons sur la possibilité de créer une dynamique interactive entre intervention sur le terrain et recherche scientifique dans le domaine de la formation. Les terrains ... [more ▼]

Dans cette contribution, nous nous penchons sur la possibilité de créer une dynamique interactive entre intervention sur le terrain et recherche scientifique dans le domaine de la formation. Les terrains d’application se situent tous ici dans le domaine de la santé. Nous présentons quatre configurations d’une telle complémentarité. Chacune d’entre elles représente une articulation différente entre le but de développement des participants et celui de production de savoirs scientifiques. Dans le premier cas, une démarche de recherche est entreprise en amont de la conception d’une formation. La deuxième configuration illustre une recherche scientifique appliquée à un dispositif d’intervention existant et qui vient en retour en modifier la logique. Pour la troisième, il s’agit d’une articulation continue entre recherche et formation s’alimentant mutuellement dans une logique de recherche-action. Enfin, la quatrième partie se penche sur trois dispositifs pédagogiques dont la caractéristique est de combiner des intentions formatives avec des préoccupations de recherche [less ▲]

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See detailLa ceramica della Schola del Traiano a Ostia Antica
Deru, Xavier ULg; Desbat, Armand; Dienst, Simon ULg et al

in Forum Romanum Belgicum (in press)

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See detailsynthéticité et intuition en mathématiques contemporaines : Kant au-delà de Kant
Mazurkiewicz, Stany ULg

in Eikasia. Revista de Filosofia. (in press)

Ce texte entend réévaluer l'idée de "pure synthèse intellectuelle" que l'on trouve chez Kant. Celle-ci cadre avec la pratique mathématique et métamathématique postérieure à Kant. Elle permet de dépasser l ... [more ▼]

Ce texte entend réévaluer l'idée de "pure synthèse intellectuelle" que l'on trouve chez Kant. Celle-ci cadre avec la pratique mathématique et métamathématique postérieure à Kant. Elle permet de dépasser l'alternative entre l'intuitionnisme développé dans la Critique de la raison pure et la fondation de la mathématique sur une logique formelle analytique. Je montre que cette idée convient à Bolzano et à Dedekind, dont je soutiens que les projets sont irréductibles à du logicisme et qui sont dès lors bien plus "kantiens" qu'il n'y paraît. [less ▲]

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See detailLes références à la maladie et à son traitement dans les archives de Zénon
Ricciardetto, Antonio ULg

in Histoire des Sciences Médicales (in press)

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See detailL’emblématique de Louise de Savoie
Fagnart, Laure ULg; Girault, Pierre-Gilles

in Armas e Troféus. Rivista de Historia, Heraldica, Genealogia (in press)

A l'occasion de cette étude, à la suite des travaux d'Anne-Marie Lecoq (1987), nous sommes revenus sur le discours héraldique de la comtesse et duchesse d'Angoulême, Louise de Savoie, l'influente mère de ... [more ▼]

A l'occasion de cette étude, à la suite des travaux d'Anne-Marie Lecoq (1987), nous sommes revenus sur le discours héraldique de la comtesse et duchesse d'Angoulême, Louise de Savoie, l'influente mère de François Ier. Nous avons présenté et explicité ses devises favorites, à savoir la cordelière, qui évoque autant le nœud de Savoie que la cordelière franciscaine, le vol, sans doute choisi puisque l’aile évoque le L de Louise par homophonie, le bouquet de lis ou le cygne « navré », mais aussi les écus et les monogrammes qui lui sont associés et qui ponctuent enluminures, tapisseries, bas-reliefs et éléments sculptés de l’architecture. Notre intention a été de montrer d’une part comment Louise de Savoie manifeste, par l’intermédiaire de ces signes emblématiques, son identité et son pouvoir, d’autre part comment elle construit, par leur biais, un patrimoine, mental, susceptible de renforcer son clan et ses héritiers. [less ▲]

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See detailDonnées des bases latines du LASLA et classification générique
Longrée, Dominique ULg

in Les Etudes Classiques (in press)

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See detailStudy of the evolution of the osteoarthritis pathology and the mechanical properties of cartilage in a spontaneous osteoarthritis model in the Dunkin-Hartley guinea pigs.
Legrand, Catherine ULg; Centonze, Prescilia ULg; Comblain, Fanny ULg et al

in Osteoarthritis and Cartilage (2017, April), 25

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan con- tent, the integrity of the tidemark, the cellularity, and osteophytes ... [more ▼]

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan con- tent, the integrity of the tidemark, the cellularity, and osteophytes. In parallel to these histological analyzes, we studied the mechanical properties of cartilage at different stages of disease progression in the Dunkin-Hartley guinea pigs. We also correlated the severity of histo- logical lesions with the mechanical properties of cartilage. [less ▲]

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See detailContrôle du mouvement lombopelvien et football
Grosdent, Stéphanie ULg; Demoulin, Christophe ULg; Cortès Flores, A. et al

in Kinesitherapie Revue (2017, April), 184

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See detailAn innovative non-animal chitosan hydrogel is able to restore the rheology of osteoarthritis synovial fluid ex vivo
Henrotin, Yves ULg; Rocasalbas, Guillem; Chausson, Mickaël et al

in Osteoarthritis and Cartilage (2017, April)

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See detailTraduction en français du "back pain attitudes questionnaire" et étude de ses qualités métrologiques
Demoulin, Christophe ULg; hALLEUX, V.; DARLOW, B. et al

in Kinesitherapie Revue (2017, April), 184

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See detailA Markov Chain Monte Carlo Cellular Automata Model to Simulate Urban Growth
El Saeid Mustafa, Ahmed Mohamed ULg; Nishida, Gen; Saadi, Ismaïl ULg et al

in GEOProcessing 2017 proceedings, The Ninth International Conference on Advanced Geographic Information Systems, Applications, and Services (2017, March 25)

This paper investigates the potential of a cellular automata (CA) model based on logistic regression (logit) and Markov Chain Monte Carlo (MCMC) to simulate the dynamics of urban growth. The model ... [more ▼]

This paper investigates the potential of a cellular automata (CA) model based on logistic regression (logit) and Markov Chain Monte Carlo (MCMC) to simulate the dynamics of urban growth. The model assesses urbanization likelihood based on (i) a set of urban development driving forces (calibrated based on logit) and (ii) the land-use of neighboring cells (calibrated based on MCMC). An innovative feature of this CA model is the incorporation of MCMC to automatically calibrate the CA neighborhood transition rules. The MCMC based CA model is applied to Wallonia region (Belgium) to simulate urban growth from 1990 to 2000 using Corine Land Cover data (CLC). The outcome of logit model is evaluated by the relative operating characteristic (ROC). The simulated map of 2000 is then validated against 2000 actual map based on cell-to-cell location agreement. The model outcomes are realistic and relatively accurate confirming the effectiveness of the proposed MCMC-CA approach. [less ▲]

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See detailImmunomodulatory effects of rapamycin in xenogeneic Graft versus Host Disease
Ehx, Grégory ULg; Hannon, Muriel ULg; DUBOIS, Sophie ULg et al

in Biology of Blood and Marrow Transplantation (2017, March), 23(3), 365366

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Several studies have suggested that rapamycin (RAPA), an mTOR ... [more ▼]

Graft-versus-host disease (GVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Several studies have suggested that rapamycin (RAPA), an mTOR inhibitor with immunosuppressive properties, may reduce GVHD severity and mortality, possibly by promoting regulatory T cells (Tregs). However, few data have been reported about the impact of this drug on overall T cell population. The present work aims at investigating the mechanisms by which RAPA impacts GVHD in a humanized mouse model of GVHD (NSG mice infused with human PBMCs). We observed that RAPA injections significantly reduced xenogeneic GVHD lethality and severity. RAPA dramatically reduced human cells chimerism in RAPA mice and increased CD4+/CD8+ T cells balance due to a lower proliferation of CD8+ T cells. In addition, the frequencies of naive CD4+ and CD8+ T cells were higher and the CD4+ T cells showed a reduced effector phenotype (CD45RO+CD27-). Further, the differentiation of helper T cells (Th1, Th2 and Th17) was significantly decreased in treated mice. Tregs were positively affected as RAPA up-regulated their expression of BCL-2 and KI67 as well as their STAT5 phosphorylation level, leading to higher Treg frequency in treated mice. Altogether these data suggest that RAPA ameliorates GVHD by lowering cytotoxic and effector CD4+ T cells frequency as well as promoting Tregs. [less ▲]

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See detailMetronomic treatments in Pediatric Neuro-Oncology, a new therapeutic alternative?
Fohn, Anaïs; Hoyoux, Claire; DRESSE, Marie-Françoise ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2017, March), 19(1), 88

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See detailImpact of an ultra-marathonof 330km on plasma levels of cardiac biomarkers
Le Goff, Caroline ULg; Kaux, Jean-François ULg; Gergelé, Laurent et al

in British Journal of Sports Medicine (2017, February), 51(4), 347

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See detailIntention, image et singularité selon le premier Sartre : réflexion sur les propriétés et les fonctions de l'acte d'imagination
Recchia, Fabio ULg

in Bulletin d'Analyse Phénoménologique (2017, February)

Partant d’une problématisation de la méthode phénoménologique mise en jeu par "L’Imaginaire", nous proposons de relire les développements de ce texte à partir de la perspective offerte par la théorie de ... [more ▼]

Partant d’une problématisation de la méthode phénoménologique mise en jeu par "L’Imaginaire", nous proposons de relire les développements de ce texte à partir de la perspective offerte par la théorie de l’intentionnalité du premier Sartre. Nous tenterons ainsi de dégager l’unité systématique du projet sartrien d’une « phénoménologie de l’image » en le rapportant aux propositions philosophiques posées de manière décisive par "l’article sur l’intentionnalité". Par ce biais, il s’agira également de fixer les propriétés de la conscience imageante, ainsi que les fonctions jouées par l’acte d’imagination dans l’économie générale de la conscience, en particulier dans l’événement de sa personnalisation. De sorte que nous parcourons les tensions reliant l’imagination de la conscience à son ipséité ; tandis que, du point de vue de l’histoire de la philosophie, nous examinerons certaines des torsions qu’appliqua Sartre sur l’analyse husserlienne de l’image afin d’approfondir celle-ci dans la direction d’une philosophie de la liberté personnelle du sujet. [less ▲]

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See detailUne anomalie du Congrès de Vienne : le Territoire neutre de Moresnet : Repenser la frontière politique et linguistiqueomalie du Congrès de Vienne : le Territoire neutre de Moresnet : Repenser la frontière politique et linguistique
Robelin, Cyril ULg

in Austriaca (2017, January)

An anomaly in the Congress of Vienna: Neutral Moresnet or how to rethink the political and linguistic boundaries. Neutral-Moresnet was a 3.4 km² neutral territory near Aachen. Its history is the result of ... [more ▼]

An anomaly in the Congress of Vienna: Neutral Moresnet or how to rethink the political and linguistic boundaries. Neutral-Moresnet was a 3.4 km² neutral territory near Aachen. Its history is the result of a misunderstanding. In Article 25 of the Vienna Final Act, Moresnet is annexed to Prussia, but in Article 66 this province is placed under Dutch sovereignty. In the site of "Vieille-Montagne” an important zinc mine is discovered. They decided to establish co-sovereignty. From then on, two commissioners oversee the area. Over time, Moresnet developed a national folklore, especially with the process of Nation-State at the end of the 19th century. This triangle is seen by foreign observers as the smallest country in the world and even as an "imaginary country" (vampires, new Eldorado). Some Esperantists hoped to make Moresnet the country of international languages ​​because in this tiny territory German, French and dialects are spoken. Moresnet rethinks the concept of border. After the Treaty of Versailles in 1919, this small state belongs to Belgium. [less ▲]

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See detailImpact of the cumulated proteins and energy deficits on ICU patient’s outcome
PAGE, Isaline ULg; Warnier, Stéphanie; NYS, Monique ULg et al

in Annals of Intensive Care (2017, January), 7(Suppl1), 200

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See detailUNE INJECTION UNIQUE DE CELLULES STROMALES MESENCHYMATEUSES AU JOUR 3 APRES GREFFE HEPATIQUE EST INSUFFISANTE POUR INDUIRE UNE TOLERANCE OPERATIONNELLE
DETRY, Olivier ULg; VANDERMEULEN, Morgan ULg; DELBOUILLE, Marie-Hélène ULg et al

in Transplant International (2017, January), 30(suppl 1), 812

Introduction: Mesenchymal stromal cell (MSC) infusion could be a mean to establish donor-specific immunological tolerance in solid organ recipients. The aim of this phase 2 study was test the hypothesis ... [more ▼]

Introduction: Mesenchymal stromal cell (MSC) infusion could be a mean to establish donor-specific immunological tolerance in solid organ recipients. The aim of this phase 2 study was test the hypothesis of possible induction of operative tolerance by third-party MSC in liver transplant (LT) recipients. Methods: 10 stable and low-risk LT recipients under standard immunosup- pression (Tac-MMF- low dose steroids) received 1.5–3 9 106/kg third-party MSCs on post-operative day 3 ` 2. By protocol, progressive weaning of immunosuppression was attempted in patients who did not develop rejection and had normal graft function and month-6 graft biopsy. Tacrolimus was progressively tapered from day 180 to be discontinued by day 270. After day- 270 graft biopsy, MMF was progressively tapered and definitely discontinued by day 365 in the absence of rejection. Results: One patient from the MSC group was excluded from immunosup- pression withdrawal attempt due to HCC recurrence, and the 9 others met the necessary criteria. In one patient, tacrolimus and MMF withdrawal was performed without rejection. In two patients, MMF monotherapy was achieved at month 9, but graft rejection occurred during MMF withdrawal and was successfully treated by tacrolimus reintroduction. In 6 patients, the transam- inases significantly increased during tacrolimus withdrawal. In these cases, withdrawal was cancelled and liver tests normalised after increase of the tacrolimus dose. No graft was lost due to the withdrawal attempt. Conclusion: A single post transplant MSC injection is not sufficient to induce operative tolerance after LT. [less ▲]

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See detailQuartz-enhanced photo-acoustic spectroscopy for breath analyses
Petersen, J; Lamard, L; Feng, P et al

in Proceedings SPIE (2017, January), 10055

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See detailUne série consécutive de 125 greffes hépatiques à partir de donneurs cadavériques en mort circulatoire
DETRY, Olivier ULg; MEURISSE, Nicolas ULg; HANS, Marie-France ULg et al

in Transplant International (2017, January), 30(Suppl 1), 2481

Introduction: Donation after circulatory death (DCD) has been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of graft loss and ... [more ▼]

Introduction: Donation after circulatory death (DCD) has been proposed to partially overcome the organ donor shortage. DCD-LT remains controversial, with reported increased risk of graft loss and retransplantation. The authors retrospectively reviewed a single centre experience with controlled DCD-LT in a 14-year period. Patients and Methods: 125 DCD-LT were consecutively performed between 2003 and 2016. All donation and procurement procedures were performed as controlled DCD in operative rooms. Data are presented as median (ranges). Median donor age was 56 years (16–84). Most grafts were flushed with HTK solution in the first part of experience, and more recently with IGL1. Allocation was centre-based. Median follow-up was 52 (1–164) months. No patient was lost to follow-up. Results: Median total DCD warm ischemia was 19 min (9–39). Median cold ischemia was 238 min (105–576). Patient survivals were 90.2%, 77.5% and 74.5 % at 1.3 and 5 years, respectively. Graft survivals were 87.7%, 76.3% and 73.2% at 1.3 and 5 years, respectively. Biliary complications included anas- tomotic strictures and extrahepatic main bile duct ischemic obstruction, that were managed either by endoscopy or hepatico-jejunostomy. No PNF was observed in this series and one graft was lost due to ischemic cholangiopathy. Discussion: In this series, DCD LT appears to provide results similar to classical LT. Short cold ischemia and recipient selection with low MELD score may be the keys to good results in DCD LT, in terms of graft survival and avoidance of ischemic cholangiopathy. [less ▲]

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See detailOn the Elaboration of Metal-Ceramic Composite Coatings by Laser Cladding
Mertens, Anne ULg; L'Hoest, Thibaut; Magnien, Julien et al

in Materials Science Forum (2017), 879

This paper reports on a preliminary investigation into the elaboration, by the additive process known as laser cladding, of composite coatings with a matrix of stainless steel 316L reinforced with varying ... [more ▼]

This paper reports on a preliminary investigation into the elaboration, by the additive process known as laser cladding, of composite coatings with a matrix of stainless steel 316L reinforced with varying contents of tungsten (WC) or silicon carbides (SiC) particles. Laser cladding is characterised by ultra-fast solidification and cooling rates, thus giving rise to ultra-fine out-of-equilibrium microstructures and potentially enhanced mechanical properties. Both types of composite coatings – i.e. with SiC or WC ‒ are compared in terms of their microstructures and hardness. Special attention is given to the dissolution of the carbides particles and to interfacial reactions taking place between the particles and the metallic matrix. [less ▲]

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See detailPROPOSITION D'UN SUPPORT D'AIDE À LA DÉCISION POUR L'AMÉLIORATION DE L'ACCÈS À UNE EAU SOUTERRAINE DE MEILLEURE QUALITÉ DANS UN CONTEXTE DE CONTAMINATION GÉOGÉNIQUE AU FLUORURE AU BENIN (AFRIQUE DE L'OUEST)
Tossou, Joël; Hermans, Thomas ULg; Orban, Philippe ULg et al

in Geo-Eco-Trop : Revue Internationale de Géologie, de Géographie et d'Ecologie Tropicales (2017)

Les eaux souterraines des aquifères de socle cristallin de la partie centrale du Bénin (Département des Collines) présentent des concentrations élevées en fluorure, allant jusqu'à 7 mg/L alors que la ... [more ▼]

Les eaux souterraines des aquifères de socle cristallin de la partie centrale du Bénin (Département des Collines) présentent des concentrations élevées en fluorure, allant jusqu'à 7 mg/L alors que la norme recommandée par l'OMS est de 1.5 mg/L. La consommation de ces eaux à fortes teneurs en fluorure impacte la santé humaine. La population de la région est effectivement largement affectée par la fluorose dentaire. Les investigations hydrogéochimiques révèlent que l’origine de ces teneurs anormales est géogénique avec une forte contribution des minéraux ferromagnésiens, principalement la biotite. Ce travail se propose de réaliser une double cartographie à l'échelle du département des Collines: (i) une carte de l'estimation des teneurs en fluorure dans les eaux souterraines par krigeage ordinaire et (ii) une carte de la probabilité d'excéder la valeur guide de l’OMS (1.5 mg/L) en fluorure dans les eaux par krigeage d'indicatrices. Outre la cartographie en elle-même, l'analyse de la structure spatiale des données (teneurs en fluorure des eaux souterraines) à travers le calcul des variogrammes montre qu'il existe un lien fort entre celles-ci et les structures géologiques dominantes, confirmant l'origine géogénique du fluorure. Ces informations cartographiques serviront de support à la décision pour les décideurs et les gestionnaires de la ressource quant au choix judicieux des zones de captage d'eau potable pour minimiser/éviter les risques de fortes teneurs en fluorure. [less ▲]

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See detailEffects of the soil pore network architecture on the soil’s physical functionnalities
Smet, Sarah ULg; Beckers, Eléonore ULg; Léonard, Angélique ULg et al

in Geophysical Research Abstracts (2017), 19

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See detailMaking Sense Out of Pulsating Pre-ELM and ELM White Dwarfs
Fontaine, Gilles; Istrate, Alina; Gianninas, Alexandros et al

in Astronomical Society of the Pacific Conference Series (2017), 509

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion ... [more ▼]

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion and rotational mixing. We find that rotational mixing is able to maintain against settling a sufficient amount of helium in the envelope in order to fuel pulsations through He II-He III ionization on the pre-ELM branch of the evolutionary track in the spectroscopic HR diagram. By the time such a low-mass white dwarf enters the ZZ Ceti instability strip on the cooling branch, settling has taken over rotational mixing and produced a pure H envelope. Such a star then pulsates again, but, this time, as a DA white dwarf of the ZZ Ceti type. [less ▲]

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See detailEarthquake imprints on a lacustrine deltaic system: Example of the Kürk Delta along the East Anatolian Fault (Turkey)
Hubert, Aurelia ULg; El Ouahabi, Meriam ULg; Moreno, David et al

in Geophysical Research Abstracts (2017), 19

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See detailThe theoretical instability strip of V777 Her white dwarfs
Van Grootel, Valérie ULg; Fontaine, Gilles; Brassard, Pierre et al

in Astronomical Society of the Pacific Conference Series (2017), 509

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See detailAssessing Inter-and Intramolecular Continuous-Flow Strategies towards Methylphenidate Hydrochloride
Gerardy, Romaric ULg; Winter, Marc; Vizza, Alessandra et al

in Reaction Chemistry and Engineering (2017)

The batch-to-flow translation of inter- and intramolecular strategies for the diastereoselective preparation of the active pharmaceutical ingredient threo-methylphenidate hydrochloride is presented. Both ... [more ▼]

The batch-to-flow translation of inter- and intramolecular strategies for the diastereoselective preparation of the active pharmaceutical ingredient threo-methylphenidate hydrochloride is presented. Both inter- and intramolecular strategies imply the telescoping of multiple processing steps and the generation of unstable diazospecies under continuous-flow conditions. The intermolecular strategy relies on an unprecedented continuous-flow Rh-catalyzed intermolecular C-H carbene insertion, providing enriched threo-N-Boc methylphenidate in 38% or 19% isolated yield according to sequential or fully telescoped processes, respectively. Quantitative Boc-deprotection is carried out off-line. The intramolecular strategy relies on a continuous-flow thermal intramolecular C-H carbene insertion, providing enriched threo-methylphenidate hydrochloride in 70% isolated yield. A continuous-flow photochemical alternative is also presented. The critical step of the most promising intramolecular strategy is implemented on mesoscale in a pilot-scale continuous-flow reactor. [less ▲]

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See detailAssessing Inter- and Intramolecular Continuous-Flow Strategies towards Methylphenidate Hydrochloride
Gerardy, Romaric ULg; Winter, Marc; Vizza, Alessandra et al

in Reaction Chemistry and Engineering (2017), 2(2), 149-158

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See detailEnergetic and Environmental Performances of a Domestic Hot Water Condensing Boiler Fired by Wood Pellets
Ngendakumana, Philippe ULg; Gabriele, Fabian; Restivo, Yannick et al

in Energy Procedia (2017)

In order to assess the performances of the domestic heating boilers with a CE mark, a wood pellets fired condensing boiler has been purchased and installed in the Laboratory for tests. The objective of ... [more ▼]

In order to assess the performances of the domestic heating boilers with a CE mark, a wood pellets fired condensing boiler has been purchased and installed in the Laboratory for tests. The objective of the study was not only to check the announced performances, but mainly to investigate the influence of the different parameters affecting the functioning of the boiler, the thermal efficiency and the pollutants (NOx and CO) emission being aimed at. Tests have been performed to study the influence of the cycling frequency of the burner functioning, the overall excess air, the return water temperature, and the output power of the boiler. As announced by the manufacturer, the tested boiler fulfils the requirements of the Blue Angel Label, but the recommended value for the excess air (1.2) can be reduced to a value of about 0.4 without excessive emissions of CO. The boiler could perform better if the ON period of the cycle of the burner is increased even better if the OFF period is suppressed. The NOx are mainly formed from the nitrogen content of the pellets and their emissions can only be reduced by a lower nitrogen content of the pellets than the limit stated in the standard. Random peaks observed in the evolution of CO, the boiler being operating in steady state regime, are attributed to the combustion process of pellets which is a non-continuous process by nature. [less ▲]

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See detailA surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH)
Farhat, Khalil; Bodart, Gwennaelle; Martens, Henri ULg et al

in Neuroimmunomodulation (2017)

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See detailPreliminary assessment of the possibilities of the Particle Finite Element Method in the numerical simulation of bird impact on aeronautical structures
Cerquaglia, Marco Lucio ULg; Deliège, Geoffrey ULg; Boman, Romain ULg et al

in Procedia Engineering (2017), 173

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air ... [more ▼]

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air). From a numerical standpoint, the presence of a free surface and the strong interaction with the aircraft structures represent a limit for traditional computational fluid dynamics methods based on an Eulerian grid. On the other hand, classical Lagrangian methods cannot cope with the extremely large deformations experienced by the projectile during the impact. The Particle Finite Element Method (PFEM) is a Lagrangian particle method that can account for very large deformations, preserving the robustness and generality of the finite element method, and thus owning a key advantage over other approaches, e.g. Smoothed Particle Hydrodynamics (SPH), usually cursed with consistency and stability issues. To assess the possibilities of the method in the context of bird impact, theoretical analyses are initially performed based on the impact of a water jet on a rigid surface. Then, the influence of the geometry of a more realistic projectile is analyzed and the capability of the method to take into account separation and fragmentation is highlighted. [less ▲]

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See detailEffect of moderate increasing exercice on the mechanical balance of the knee joint in young rats
Rahnamay Moshtagh, Parisa; Korthagen, N; Plomp, S et al

in Osteoarthritis and Cartilage (2017), 25

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See detailDecision algorithms for the re-treatment with viscosupplementation in patients suffering from knee osteoarthritis
Henrotin, Yves ULg; Richette, Pascal; Raman, R et al

in Osteoarthritis and Cartilage (2017), 25

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See detailEfficacité d’un programme de rééducation active pluridisciplinaire du dos : suivi de 812 patients lombalgiques chroniques
Mahieu, Geneviève; Boogaerts, M.; Tordeurs, D. et al

in Revue du Rhumatisme (2016, December), 83S

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See detailHost Interleukin 6 and Indoleamine 2,3 Dioxygenase Regulate Inflammation in the Brain during Graft Versus Host Disease
Belle, Ludovic ULg; Koester, E; Hansen, E et al

in Blood (2016, December), 128

Graft versus host disease (GVHD) commonly induces pathological damage in peripheral target organs such as the skin, liver and gastrointestinal tract leading to well characterized organ-specific clinical ... [more ▼]

Graft versus host disease (GVHD) commonly induces pathological damage in peripheral target organs such as the skin, liver and gastrointestinal tract leading to well characterized organ-specific clinical manifestations. A number of studies, however, have shown that patients with GVHD can also have behavioral and mood alterations that can affect overall cognitive function and lead to significant impairments in quality of life. The extent to which GVHD contributes to cognitive dysfunction and induces inflammation within the central nervous system (CNS), however, has not been critically examined. To address this question, we conducted studies using two well-defined murine GVHD models [C57BL/6(H-2b)→Balb/c (H-2d) and B10.BR(H-2k)→B6 (H-2b)]. We observed that there was a significant increase in the number of donor-derived CD4+ and CD8+ T cells in the brains of GVHD recipients early (days 7 -14) and late (day 42) post transplantation compared to BM controls. Histological studies revealed activated microglial cells and CD3+ T cell infiltration in the periventricular regions of brains in GVHD recipients that were not present in BM animals. Real time q-PCR analysis also demonstrated significant increases in IFN-γ, TNF-α, and IL-6 mRNA expression indicative of a proinflammatory state. Notably, GVHD animals exhibited behavioral changes in the forced swim test and elevated plus maze which are validated assays of stress coping and anxiety, respectively. Since IL-6, in particular, plays a pivotal role in GVHD pathogenesis in murine models and humans, we examined whether blockade of IL-6 signaling altered neuroinflammation. Animals treated with an anti-IL-6R antibody had a significant reduction in the number of donor-derived CD4+ and CD8+T cells in the brain compared to isotype control-treated mice. Anti-IL-6R treatment of GVHD mice also resulted in significant reductions in IFN-γ, TNF-α, and IL-6 mRNA and normalized behavior in the forced swim test, indicative of a decreased inflammatory response. Since IL-6 is produced by a wide variety of cells, including microglial and T cells, both donor and recipient cells have the potential to modulate GVHD severity within the CNS. To define whether donor or host IL-6 production was most critical for inducing neuroinflammation, experiments were conducted employing IL-6-/- mice as either donors or recipients. Whereas the absence of IL-6 in donor-derived cells had no impact on the degree of inflammation within the CNS, recipient animals that lacked IL-6 had a significant decrease in the number of donor-derived T cells which accumulated in the brain as well as a marked reduction in inflammatory cytokines, indicating that host IL-6 production was critical. To define the downstream pathways of IL-6-mediated CNS inflammation, we examined the role of indoleamine 2,3-dioxygenase (IDO) since IL-6 has been shown to upregulate IDO-1 expression under inflammatory conditions. We observed that IDO-1 mRNA levels were significantly increased in the brains of GVHD animals, and that blockade of IL-6 signaling resulted in a marked decrease in IDO mRNA levels. Additionally, transplantation studies using IDO-/- mice revealed that host, but not donor, IDO production was required for maximal inflammatory effects. Serotoninergic projections to the prefrontal cortex (PFC), in particular, are sensitive to inflammation and contribute to stress coping behavior. Therefore, to further interrogate this pathway, we performed quantitative mass spectrometry of brain extracts from the PFC. We found that tryptophan and 5HT concentrations were not different between BM and GVHD groups. However, there was an increase in the IDO product, kynurenic acid, in GVHD recipients consistent with an increase in brain IDO expression. To provide additional support for the premise that IL-6 effects were mediated through the IDO pathway, recipient mice were treated with either 1-methyltryptophan (1-MT), a completive inhibitor of IDO, or a vehicle control. GVHD mice treated with 1-MT had decreased accumulation of T cells in the brain and normal behavior in the forced swim test, demonstrating that inhibition of IDO abrogated CNS inflammation and behavioral changes in the presence of intact IL-6 signaling. In summary, these studies demonstrate that host IL-6 and IDO regulate inflammation and adversely impact behavioral function within the brain during GVHD through the tryptophan metabolic pathway. [less ▲]

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See detailÉtude du degré de satisfaction de patients lombalgiques au sujet du site internet éducatif « Retrain Pain »
Demoulin, Christophe ULg; Blanc, A.; Wolfs, Sébastien ULg et al

in Revue du Rhumatisme (2016, December), 83S

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See detailSommeil, éveil et cognition au cours du temps
Vandewalle, Gilles ULg

in Bulletin de la Société Royale des Sciences de Liège (2016, November 25)

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See detailIn Vivo Preclinical Molecular Imaging: From the Laboratory Bench to the Patient.
Plenevaux, Alain ULg

in Pharmaceuticals (2016, November 18), 9(4), 73

Preclinical molecular imaging plays a key role in the study of diseases and the development, evaluation, andvalidation of novel treatment and diagnostic techniques. The actual aim is to facilitate the ... [more ▼]

Preclinical molecular imaging plays a key role in the study of diseases and the development, evaluation, andvalidation of novel treatment and diagnostic techniques. The actual aim is to facilitate the translation of innovative therapies and diagnostic agents into patients by providing in vivo proof-of-principle data in animal models of diseases and accordingly match some of the legal requirements before human clinical trials. The real power of preclinical imaging stems from the fact that in vivo data are non-invasively collected, thus making longitudinal studies possible. The evolution of the disease or the actual impact of innovative treatments can be evaluated in the same animal over a long period of time. The major modalities used in preclinical molecular imaging (all present in our laboratory) are the positron emission tomography (microPET), the X-ray tomodensitometry (microCT) and the magnetic resonance imaging (microMRI). The GIGA-CRC In vivo Imaging at ULg is a multidisciplinary laboratory which relies on a medical cyclotron for radioisotope productions, a radiochemistry unit for the development of new radiopharmaceuticals and process automation, a GMP unit for radiopharmaceutical productions, a preclinical imaging unit and a clinical imagingplatform (with MRI, PET, EEG, TMS, . . . ). All expertise and qualified staff are present on site. Our laboratory has all necessary permission and approval for radiopharmaceutical productions and human clinical trials. During this presentation, we will take as an example the development of the first SV2A radioligand [18F]UCB-H (a-b) to illustrate how we can bring new ideas from the laboratory bench to the patient (Bretin, F., et al. Eur. J. Nucl. Med. Mol. Imaging Res. 2013, 3, 35; Warnock, G., et al. J. Nucl. Med. 2014, 55, 1336–1341). [less ▲]

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See detailDevices for less invasive surfactant therapy: a manikin study
RIGO, Vincent ULg; Debauche, Christian; Maton, Pierre et al

in European Journal of Pediatrics (2016, November), 175(11), 1756

Background: “Less invasive surfactant therapy” (LIST), or tracheal instillation of surfactant through a small catheter in spontaneously breathing infants, is gaining popularity. Different catheters are ... [more ▼]

Background: “Less invasive surfactant therapy” (LIST), or tracheal instillation of surfactant through a small catheter in spontaneously breathing infants, is gaining popularity. Different catheters are currently used for this purpose: a nasogastric tube inserted with (LISA) or without (Take Care) Magill’s forceps, a 13 cm 16G adult angiocath (MIST), a 30 cm F4 angiography catheter (Stockholm). We developed a specific device by combining a F5 umbilical catheter and an intubation stylet (Liege). We aimed to compare those 5 devices using INSURE as a reference. Methods: 20 neonatologists from 4 institutions supporting different surfactant instillation policies intubated 2 manikin heads with the 5 catheters and an endotracheal tube in a predetermined random sequence. Water was flushed trough the catheter. Video review provided times between laryngoscope (T1) or catheter insertion (T2) in the mouth and water flowing from the trachea. Participants gave an ease of use score (range: 1-9) for each catheter. Results: Procedural times were longer with the Take Care method and shorter with the Liège device (Table). Failure rates were higher for LIST procedures than for INSURE. Take Care and LISA were rated as more difficult, while Liège, Stockholm and INSURE were considered easier. Conclusions: LIST procedures remain difficult, even on a manikin. The choice of catheter is important. A device combining the rigidity of a stylet with the soft distal end of an umbilical catheter is associated with procedures of shorter duration and is considered easier by neonatologists. [less ▲]

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See detailEfficient Computation of the Minimum of Shape Quality Measures on Curvilinear Finite Elements
Johnen, Amaury ULg; Geuzaine, Christophe ULg; Toulorge, Thomas et al

in Procedia Engineering (2016, November), 163

We present a method for computing robust shape quality measures defined for any order of finite elements. All type of elements are considered, including pyramids. The measures are defined as the minimum ... [more ▼]

We present a method for computing robust shape quality measures defined for any order of finite elements. All type of elements are considered, including pyramids. The measures are defined as the minimum of the pointwise quality of curved elements. The computation of the minimum, based on previous work presented by Johnen et al. (2013) [1] and [2], is very efficient. The key feature is to expand polynomial quantities into Bézier bases which allows to compute sharp bounds on the minimum of the pointwise quality measures. [less ▲]

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See detailExcited hyperons of the N = 2 band in the 1/Nc expansion
Stancu, Floarea ULg

in Bled Workshops in Physics (2016, November), 17(1), 25-31

The spectrum of excited baryons in the $N$ = 2 band is reanalyzed in the $1/N_c$ expansion method, with emphasis on hyperons. Predictions are made for the classification of these excited baryons into SU(3 ... [more ▼]

The spectrum of excited baryons in the $N$ = 2 band is reanalyzed in the $1/N_c$ expansion method, with emphasis on hyperons. Predictions are made for the classification of these excited baryons into SU(3) singlets, octets and decuplets. [less ▲]

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See detailCase report: Ovarian fibroma in a mare – Hormonal considerations
Ponthier, Jérôme ULg; Salciccia, Alexandra ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (2016, October 27), 51(supplement 2), 132

This report shows that, as in humans, AMH as well as steroids productions are low in case of ovarian fibroma, thus preserving normal cyclicity.

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See detailTowards a normalised 3D Geovisualisation : the viewpoint management
Neuville, Romain ULg; Poux, Florent ULg; Hallot, Pierre ULg et al

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2016, October 05), IV-2(W1), 179-186

This paper deals with the viewpoint management in 3D environments considering an allocentric environment. The recent advances in computer sciences and the growing number of affordable remote sensors lead ... [more ▼]

This paper deals with the viewpoint management in 3D environments considering an allocentric environment. The recent advances in computer sciences and the growing number of affordable remote sensors lead to impressive improvements in the 3D visualisation. Despite some research relating to the analysis of visual variables used in 3D environments, we notice that it lacks a real standardisation of 3D representation rules. In this paper we study the “viewpoint” as being the first considered parameter for a normalised visualisation of 3D data. Unlike in a 2D environment, the viewing direction is not only fixed in a top down direction in 3D. A non-optimal camera location means a poor 3D representation in terms of relayed information. Based on this statement we propose a model based on the analysis of the computational display pixels that determines a viewpoint maximising the relayed information according to one kind of query. We developed an OpenGL prototype working on screen pixels that allows to determine the optimal camera location based on a screen pixels colour algorithm. The viewpoint management constitutes a first step towards a normalised 3D geovisualisation. [less ▲]

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See detailSMART POINT CLOUD: DEFINITION AND REMAINING CHALLENGES
Poux, Florent ULg; Neuville, Romain ULg; Hallot, Pierre ULg et al

in ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2016, October 05), IV-2(W1), 119-127

Dealing with coloured point cloud acquired from terrestrial laser scanner, this paper identifies remaining challenges for a new data structure: the smart point cloud. This concept arises with the ... [more ▼]

Dealing with coloured point cloud acquired from terrestrial laser scanner, this paper identifies remaining challenges for a new data structure: the smart point cloud. This concept arises with the statement that massive and discretized spatial information from active remote sensing technology is often underused due to data mining limitations. The generalisation of point cloud data associated with the heterogeneity and temporality of such datasets is the main issue regarding structure, segmentation, classification, and interaction for an immediate understanding. We propose to use both point cloud properties and human knowledge through machine learning to rapidly extract pertinent information, using user-centered information (smart data) rather than raw data. A review of feature detection, machine learning frameworks and database systems indexed both for mining queries and data visualisation is studied. Based on existing approaches, we propose a new 3-block flexible framework around device expertise, analytic expertise and domain base reflexion. This contribution serves as the first step for the realisation of a comprehensive smart point cloud data structure [less ▲]

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See detailSurvey for Ortho-to-Para Abundance Ratios (OPRs) of NH2 in Comets: Revisit to the Meaning of OPRs of Cometary Volatiles
Kawakita, Hideyo; Shinnaka, Yoshiharu; Jehin, Emmanuel ULg et al

in Bulletin of the American Astronomical Society (2016, October 01), 48

Since molecules having identical protons can be classified into nuclear-spin isomers (e.g., ortho-H[SUB]2[/SUB]O and para-H[SUB]2[/SUB]O for water) and their inter-conversions by radiative and non ... [more ▼]

Since molecules having identical protons can be classified into nuclear-spin isomers (e.g., ortho-H[SUB]2[/SUB]O and para-H[SUB]2[/SUB]O for water) and their inter-conversions by radiative and non-destructive collisional processes are believed to be very slow, the ortho-to-para abundance ratios (OPRs) of cometary volatiles such as H[SUB]2[/SUB]O, NH[SUB]3[/SUB] and CH[SUB]4[/SUB] in coma have been considered as primordial characters of cometary molecules [1]. Those ratios are usually interpreted as nuclear-spin temperatures although the real meaning of OPRs is in strong debate. Recent progress in laboratory studies about nuclear-spin conversion in gas- and solid-phases [2,3] revealed short-time nuclear-spin conversions for water, and we have to reconsider the interpretation for observed OPRs of cometary volatiles. We have already performed the survey for OPRs of NH[SUB]2[/SUB] in more than 20 comets by large aperture telescopes with high-resolution spectrographs (UVES/VLT, HDS/Subaru, etc.) in the optical wavelength region [4]. The observed OPRs of ammonia estimated from OPRs of NH[SUB]2[/SUB], cluster around ~1.1 (cf. 1.0 as a high-temperature limit), indicative of ~30 K as nuclear-spin temperatures. We present our latest results for OPRs of cometary NH[SUB]2[/SUB] and discuss about the real meaning of OPRs of cometary ammonia, in relation to OPRs of water in cometary coma. Chemical processes in the inner coma may play an important role to achieve un-equilibrated OPRs of cometary volatiles in coma.This work was financially supported by MEXT Supported Program for the Strategic Research Foundation at Private Universities, 2014–2018 (No. S1411028) (HK) and by Graint-in-Aid for JSPS Fellows, 15J10864 (YS).References:[1] Mumma & Charnley, 2011, Annu. Rev. Astro. Astrophys. 49, 471.[2] Hama & Watanabe, 2013, Chem. Rev. 113, 8783.[3] Hama et al., 2008, Science 351, 6268.[4] Shinnaka et al., 2011, ApJ 729, 81. [less ▲]

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See detailThe OD/OH Isotope Ratio in Comets 8P/Tuttle and C/2012 F6 (Lemmon)
Rousselot, Philippe; Jehin, Emmanuel ULg; Hutsemekers, Damien ULg et al

in Bulletin of the American Astronomical Society (2016, October 01), 48

The determination of isotopic ratios in solar system objects is an important source of information about their origin, especially for comets. Among these ratios the D/H is of particular importance because ... [more ▼]

The determination of isotopic ratios in solar system objects is an important source of information about their origin, especially for comets. Among these ratios the D/H is of particular importance because of its sensitivity to fractionation processes and physical environment, and the abundance of hydrogen in the solar system. The main molecule used to derive this ratio in comets is water. So far, apart water, only HCN has permitted to derive D/H ratio and not only upper limits.Most of the existing determinations of D/H in water molecules have been obtained by spectroscopic observations of water lines in the sub-mm or near infrared range [1,2]. So far only one measurement has been based on OD/OH emission lines radicals in the near-UV [3] and another one on the Lyman-alpha D emission [4]. In situ measurements have also been obtained in comets 1P/Halley and 67P/Churyumov-Gerasimenko using mass spectrometer [5,6,7,8].In this work we have used the OH and OD ultraviolet bands at 310 nm observed with the ESO 8-m Very Large Telescope feeding the Ultraviolet-Visual Echelle Spectrograph (UVES) for measuring the D/H ratio in comets 8P/Tuttle and C/2012 F6 (Lemmon). The OH and OD being the photodissociation products of H[SUB]2[/SUB]O and HDO such observations allow to derive D/H ratio for water molecules. This work constitutes an independant determination of the D/H ratios already published for these comets and based on observations performed in the sub-mm and near infrared range of H[SUB]2[/SUB]O and HDO lines. We present our modeling, data analysis and numerical values obtained for this ratio.[1] D. Bockelée-Morvan et al., 2015, SSR 197, 47-83 [2] N. Biver et al., 2016, A&A 589, id A78, 11p [3] D. Hutsemékers et al., 2008, A&A 490, L31 [4] H.A. Weaver et al., 2008, LPI Contributions 1405, 8216 [5] H. Balsiger, K. Altwegg, J. Geiss, 1995, JGR 100, 5827 [6] P. Eberhardt et al., 1995, A&A 302, 301 [7] R.H. Brown et al., 2012, PSS 60, 166 [8] K. Alwegg et al., 2015, Science 347, article id. 1261952 [less ▲]

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See detailAutologous osteoblastic cells (PREOBy) versus concentrated bone marrow implantation in osteonecrosis of the femoral head: A randomized study
HAUZEUR, Jean-Philippe ULg; Tungouz, Michel; LECHANTEUR, Chantal ULg et al

in Revue de Chirurgie Orthopédique et Traumatologie (2016, October), 102

In non-traumatic osteonecrosis of the femoral head (ONFH), implantation of bone marrow concentrate (BMC) containing mesenchymal stem cells (MSC) could delay ONFH progression and improve symptoms (Hernigou ... [more ▼]

In non-traumatic osteonecrosis of the femoral head (ONFH), implantation of bone marrow concentrate (BMC) containing mesenchymal stem cells (MSC) could delay ONFH progression and improve symptoms (Hernigou 2002, Gangji 2004). The next step was to assess the hypothesis that a population of autologous osteoblastic cells (OB) consisting in a more differentiated cell than MSC, could be more efficacious than BMC in early stages ON. [less ▲]

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See detailWhat are the optimal walking tests to assess disability progression?
Pierard, Sébastien ULg; Van Droogenbroeck, Marc ULg

in Multiple Sclerosis Journal (2016, September 16), 22(S3), 452-453

Background. Therapy success is assumed when there is no evidence of disease activity. Clues to show it include an MRI, the relapses history, questionnaires, and clinical measures to assess the disability ... [more ▼]

Background. Therapy success is assumed when there is no evidence of disease activity. Clues to show it include an MRI, the relapses history, questionnaires, and clinical measures to assess the disability progression. Especially gait analysis plays a major role as gait impairment is considered by patients as the most disabling symptom. Too often only the walking speed is measured. New technologies (eg GAIMS, see ECTRIMS 2012-15) measure many spatiotemporal gait parameters, even during long tests (\eg 6min, 500m), without equipping patients with markers or sensors. Moreover, various tests can be done, depending on the length and type of walk (comfortable pace --C--, as fast as possible --F--, tandem gait --T--). Objective. Determine if there is an advantage to perform various walking tests, and which test or combination of tests brings the higher amount of information about the patient state in a reasonable amount of acquisition time. Methods. The system GAIMS provided 434 recordings of the gait parameters of healthy people and 60 recordings of MS patients with EDSS<= 4. They performed 12 tests (25ft C+F+T each twice, 20m C+F+T, 100m C+F, 500m F). To assess the ability of these clinical outcome measures to detect disability progression, we evaluate the possibility of differentiating the persons below a given EDSS threshold (0.25) from those above it based only on the measured gait parameters. For individual tests, we use the classifier of Azrour (ESANN 2014). All subsets of the tests are also considered, by combining the individual classifiers and determining automatically the optimal relative importance of the tests with the linear support vector machine (SVM) technique. The ability to detect the disability progression is quantified by the performance (area under the ROC curve --AUC-- and the maximum achievable balanced accuracy --MBA--) of the corresponding classifiers. Results. The best test alone is the 500m F (note that the walking speed measured during it is the gait parameter best correlated with the EDSS). Combining several tests leads to a better performance. A performance (MBA=95.7%, AUC=0.983) close to the best achievable one can be obtained with 6 tests only (25ft C twice, 25tf F twice, 20m C, 20m T). Conclusions. The clinical gait analysis can help to detect disability progression. While considering different types of walking tests improves the ability of taking decisions, we showed that performing 6 tests for a total of 70.48m suffices. [less ▲]

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See detailModels of rotating stars constrained by asteroseismic measurements of red giants
Eggenberger, P.; Lagarde, N.; Miglio, A. et al

in Astronomische Nachrichten (2016, September 01), 337(8-9), 832-836

Solar-like oscillations have now been characterized for a large number of stars, thanks to asteroseismic data obtained recently by space missions. This has led to the determination of the global and ... [more ▼]

Solar-like oscillations have now been characterized for a large number of stars, thanks to asteroseismic data obtained recently by space missions. This has led to the determination of the global and internal properties of these stars. In particular, core rotation rates have been obtained for red-giant stars, which is of prime importance to progress in the modelling of the dynamical processes at work in stellar interiors. In this presentation, we discuss which constraints can be brought by these asteroseismic measurements on stellar models that include rotational effects. Similarly to the solar case, we show that an efficient mechanism is required for the transport of angular momentum in the radiative zones of red giants. The efficiency of this transport process can be determined by asteroseismic observations of red-giant stars. [less ▲]

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See detailUniversité d'été du Cifen 2015 : insertion professionnelle et parcours enseignants. Mise en perspective et présentation du programme de la journée
Simons, Germain ULg

in Didactiques en Pratique (2016, September), 2

Cette communication ouvrait l'Université d'été 2015 du Cifen. La thématique du colloque : "insertion professionnelle et parcours enseignants" y fut brièvement présentée, de même que les questions qui ... [more ▼]

Cette communication ouvrait l'Université d'été 2015 du Cifen. La thématique du colloque : "insertion professionnelle et parcours enseignants" y fut brièvement présentée, de même que les questions qui allaient baliser cette journée d'études. Ensuite le programme de la journée fut rappelé aux participants. [less ▲]

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See detailValeurs de référence de débit de filtration glomérulaire en population noire-africaine
Yayo, E; Monnet, D; Attoungbré, M.-L. et al

in Néphrologie & Thérapeutique (2016, September), 12(5), 273

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See detailCompte rendu de l’atelier « Entretiens de stages »
Francois, Nathalie ULg; Simons, Germain ULg; Van Hoof, Florence ULg

in Didactiques en Pratique (2016, September), 2

Cet article présente le compte rendu d'un atelier portant sur les entretiens de stages dans l'enseignement. Lors de l'atelier, les participants étaient invités à analyser des extraits d'entretiens entre ... [more ▼]

Cet article présente le compte rendu d'un atelier portant sur les entretiens de stages dans l'enseignement. Lors de l'atelier, les participants étaient invités à analyser des extraits d'entretiens entre un futur enseignant, son maitre de stage et son formateur. La discussion collective a permis ensuite de mettre en exergue des éléments potentiellement porteurs et facilitateurs dans ces situations d'entretiens. [less ▲]

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See detailGait pattern of healthy old people for fast walking condition
GILLAIN, Sophie ULg; Boutaayamou, Mohamed ULg; Schwartz, Cédric ULg et al

in Gerontechnology (2016, September)

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See detailSystematic Downstream Development, Optimization and Equipment Design for Biobased Products and Processes
Bednarz, Andreas; Rüngeler, Bettina; Scherübel, Peter et al

in Chemie Ingenieur Technik (2016, September), 88(9), 1375-1376

Biobased synthesis poses specific challenges due to the properties of raw materials, intermediates, and products. They are induced by the higher oxygen content as compared to fossil feedstock. Thus low ... [more ▼]

Biobased synthesis poses specific challenges due to the properties of raw materials, intermediates, and products. They are induced by the higher oxygen content as compared to fossil feedstock. Thus low vapor pressure, higher viscosity, low concentration in aqueous solution will require new, preferably liquid-based downstream processes, for which many different options can be proposed. A systematic method to evaluate such a multitude of options based on cascaded option trees is presented, which combines representation and evaluation of options on a suitably chosen level of detail. Criteria, which have to be fulfilled by the options, are flexibly evaluated ranging from input of experts to detailed simulation. Clear visualization also allows transparent communication of results to members of interdisciplinary teams and project partners. The method is demonstrated for extractive separation steps including real-world problems encountered. This includes high viscosities, presence of solids or microorganisms leading to crud formation, and optimization of process conditions solving the conflicting challenges balancing e.g. between low toxicity to microorganisms and process efficiency. [less ▲]

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See detailGait pattern of healthy old people for dual task walking condition
GILLAIN, Sophie ULg; Boutaayamou, Mohamed ULg; Schwartz, Cédric ULg et al

in Gerontechnology (2016, September)

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See detailHome blood pressure in kidney transplant recipients (Ktr) - Validity of different schedules of self-monitoring
SAINT-REMY, Annie ULg; WEEKERS, Laurent ULg; BONVOISIN, Catherine ULg et al

in Journal of Hypertension (2016, September), 34(e supplement 2), 119

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See detailAge-related changes in the modulation of attentional brain responses to sleep pressure at night
Schmidt, Christina ULg; Reichert, Carolin; Maire, Micheline et al

in Journal of Sleep Research (2016, September)

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See detailSatellite Formation Control Using Continuous Adaptive Sliding Mode Controller
Cho, Hancheol ULg; Kerschen, Gaëtan ULg

in AIAA/AAS Astrodynamics Specialist Conference (2016, September)

The focus of this study is on the development of a robust controller with a simple gain adaptation for satellite formation control. The complete nonlinear dynamics of the motion of the follower satellite ... [more ▼]

The focus of this study is on the development of a robust controller with a simple gain adaptation for satellite formation control. The complete nonlinear dynamics of the motion of the follower satellite relative to the leader satellite is considered and the rigorous proof for the stability of the controlled formation system is given in the presence of unknown external disturbances and unknown mass of the follower satellite. Although the controller design is based on the concept of sliding mode control, the proposed control strategy is free from chattering and guarantees a finite-time convergence of the controlled system to the target area. Furthermore, a simple adaptive law to automatically update the control gain is suggested that does not require a priori knowledge of the uncertainties of the system. In addition, to guarantee the robustness from the beginning and to improve the transient performance, a new sliding surface is also constructed. Numerical simulations are carried out to demonstrate the effectiveness of the proposed adaptive controller to maintain a desired formation configuration by compensating for the initial offset errors and external disturbance effects including gravitational perturbations and atmospheric drag. [less ▲]

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See detailWhen to use locking implants?
Balligand, Marc ULg

in Proceedings of the 18th ESVOT congress (2016, September)

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See detailLocking implants : polyaxial systems
Balligand, Marc ULg

in Proceedings of the 18th congress 2016 (2016, September)

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See detailComparative analysis of the respiratory microbiota of healthy dogs and dogs with canine idiopathic pulmonary fibrosis
Roels, Elodie ULg; Taminiau, Bernard ULg; Darnis, Elodie ULg et al

in Journal of Veterinary Internal Medicine (2016, September)

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See detailSetting up ex-vivo biomechanics studies
Balligand, Marc ULg

in Proceedings of the 18th ESVOT congress (2016, September)

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See detailApproche stratégique de formation du personnel local au sein des ONG internationales dans un contexte incertain : cas du Burundi
Hakizumukama, Alexis ULg

in Actes des Rencontres Internationales sur la Diversité (2016, September)

The human resources management issues is a major challenge for the current and future international organizations, especially those of the non merchant sector, as the environmental context in which they ... [more ▼]

The human resources management issues is a major challenge for the current and future international organizations, especially those of the non merchant sector, as the environmental context in which they operate is changing more and more quickly. Thus, beyond the mobilization and the gradual professionalization of volunteers to adapt their contribution to the missions of NGOs, these organizations are also experiencing a real need for personnel able to adapt without too much difficulty, the complexity of the local context whose evolution often proves unpredictable. But this labor, multiple and high skills, is often scarce on the local labor market. This finding essentially explains the presence of expatriates who work daily alongside local employees who may be employees and volunteers, and whose management requires a sufficiently coherent strategy with organizational goals and interests of these stakeholders. HRM strategy implementation within the subsidiaries shall submit their leaders to multiple challenges brought by a set of actors focused on different and even divergent interests. The model and HRM practices in any organization, reflect the dominant HRM strategy. During our research, we pay special attention to the evolution of HRM models (Pichault and Nizet, 2013) and strategy implemented in the training of local personnel by subsidiaries studied by relying on the theory of social regulation (Reynaud, 1997, 1999). The conclusions of our work indicate that the development of HRM strategy following a joint regulatory process appears best suited to international NGOs working in uncertain environment. [less ▲]

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See detailInvolvement of membrane remodelling induced by fatty acids in the regulation of the NLRP3 inflammasome activity in human macrophages
Gianfrancesco, Marco ULg; Dehairs, Jonas; Bloch, Katarzyna et al

in Diabetologia (2016, August), 59(Supplement 1), 291

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See detailREVISITED SAMPLE PREPARATION APPROACH FOR DIOXIN MEASUREMENTS IN HUMAN SERUM SAMPLES
Calaprice, Chiara ULg; Focant, Jean-François ULg

in Organohalogen Compounds (2016, August), 78

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See detailEVALUATING THE CHEMICAL SAFETY OF EDIBLE INSECTS
Poma, G; Cuykx, M; Amato, E et al

in Organohalogen Compounds (2016, August), 78

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See detailEVALUATION OF FISH EXPOSURE TO POP-LIKE (ORGANOTIN) COMPOUNDS IN SEPETIBA BAY (RIO DE JANEIRO STATE, BRAZIL) THROUGH HEPATIC TOTAL TIN CONCENTRATIONS
Paiva, TC; Schilithz, PF; Bisi, TL et al

in Organohalogen Compounds (2016, August)

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See detailModel-Based Decision Support Algorithm to Guide Fluid Resuscitation
Pironet, Antoine ULg; Dauby, Pierre ULg; MORIMONT, Philippe ULg et al

in IFAC-PapersOnLine (2016, July 26), 49(5), 224-229

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See detailNew antimalarial compounds isolated from Poupartia borbonica, a Mascarene Islands endemic plant
Ledoux, Allison ULg; Jansen, Olivia ULg; St-Gelais, Alexis et al

in Planta Medica (2016, July), 82(S01), 1-381

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See detailDistinct cerebral metabolic patterns related to high pain sensitivity in episodic or chronic migraine patients and healthy volunteers
D'Ostilio, Kevin ULg; Lisicki Martinez, Marco ULg; Schoenen, Jean ULg et al

in Frontiers in Aging Neuroscience (2016, July)

Introduction Allodynia, i.e. pain evoked by a non-painful stimulus, is prevalent in chronic pain and in migraine where it augments with disease severity and chronicity [1]. Central sensitization is ... [more ▼]

Introduction Allodynia, i.e. pain evoked by a non-painful stimulus, is prevalent in chronic pain and in migraine where it augments with disease severity and chronicity [1]. Central sensitization is thought to be the culprit [2]. It is not known, however, which central areas are involved. The aim of the present study was to evaluate whether brain metabolism in subjects that are more sensitive to pain is different between migraine patients and healthy controls. Subjects and methods Quantitative heat sensory testing on the forehead and 18FDG-PET were performed in 55 subjects: 20 healthy volunteers (HV, 21-59 years, 5M), 21 patients with episodic migraine in the interictal phase (MO, age range: 20-63 years, 5M) and 14 patients with chronic migraine (CM, age range: 22-62 years, 1M). The 3 cohorts were subdivided according to the median heat pain threshold into subgroups with low and high pain thresholds. PET results were compared between these subgroups in each cohort. Data analyses were restricted to areas of the pain/salience matrix. Results There was no significant difference in heat pain thresholds between HV (median: 43.7 °C), MO median: 44.2°C) and CM (median: 43.3°C) (p=0.64). In an SPM-ANOVA, a contrast modelling the potential gradual effect of increased differences in pain sensitivity in relation to disease severity showed significant metabolic changes in bilateral thalamus and midbrain (p < 0.001). Additional analyses revealed that hypometabolic areas in subgroups with a low heat pain threshold differed between HV (anterior cingulate and somatosensory cortices), MO (lower pons and somatosensory cortex) and CM (midbrain and thalamus) (Figure 1). Conclusion Overall migraine patients do not have reduced heat pain thresholds. However, hypometabolic areas related to high thermal pain sensitivity are strictly cortical in HV, but comprise the pons in episodic migraine and are restricted to midbrain and thalamus in chronic migraine. The distinct central correlates of heat pain sensitivity in migraine patients might therefore represent a biomarker of migraine and its chronification. Legend to figure Figure 1. Hypometabolic areas in low pain threshold subgroups in HV (green), MO (orange) and CM (red). p < 0.01 for display purpose. Résumé en Français: Titre: Métabolisme cérébral distinct en relation avec la sensibilité à la douleur entre sujets sains, migraine épisodique et migraine chronique. Les migraineux ont une sensibilité anormale à la douleur. Les mécanismes cérébraux en sont inconnus. Nous avons comparé le métabolisme cérébral chez des sujets sains et chez des migraineux épisodiques ou chroniques et correlé les résultats avec le seuil douloureux. Les aires cérébrales hypométaboliques liées à un seuil douloureux bas diffèrent entre groupes: régions corticales chez les sujets sains, aires corticales et sous-corticales dans la migraine épisodique, régions sous-corticales dans la migraine chronique .Le contrôle central de la douleur semble modifié distinctement dans les formes de migraine, ce qui pourrait en constituer un biomarqueur et avoir des implications thérapeutiques. [less ▲]

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See detailCharacterization of the ASPIICS/OPSE metrology sub-system and PSF centroiding procedure.
Lorregia, D; Thizy, Cédric ULg; Renotte, Etienne ULg

in Proceedings of SPIE (2016, June)

Metrology in diluted systems for space applications is one of the most important technology research fields that in recent years have raised increasing interest. Many applications of astronomical ... [more ▼]

Metrology in diluted systems for space applications is one of the most important technology research fields that in recent years have raised increasing interest. Many applications of astronomical observation techniques, as coronography and interferometry get great benefit when moved in space and the employment of diluted systems represents a milestone to step-over in astronomical research. In this work, we present the Optical Position Sensors Emitter (OPSE) metrological sub-system on-board of the PROBA3. PROBA3 is an ESA technology mission that will test in-orbit many metrology techniques for the maintenance of a Formation Flying with two satellites, in this case an occulter and a main satellite housing a coronagraph named ASPIICS, kept at an average inter-distance of 144m. The scientific task is the observation of the Sun’s Corona at high spatial and temporal resolution down to 1.08R⊙. The OPSE will monitor the relative position of the two satellites and consists of 3 emitters positioned on the rear surface of the occulter, that will be observed by the coronagraph itself. A Centre of Gravity (CoG) algorithm is used to monitor the emitter’s PSF at the focal plane of the Coronagraph retrieving the Occulter position with respect to the main spacecraft. The 3 location target accuracy is 300m for lateral movement and 21cm for longitudinal movements. A description of the characterization tests on the OPSE LED sources, and of the design for a laboratory set-up for on ground testing is given with a preliminary assessment of the performances expected from the OPSE images centroiding algorithm. [less ▲]

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See detailThe satellite formation flying in lab: PROBA-3/ASPIICS metrology
Capobianco, G; Thizy, Cédric ULg; Renotte, Etienne ULg

in Proceedings of SPIE (2016, June)

Formation flying is one of the most promising techniques for the future of astronomy and astrophysics from the space. The capabilities of the rockets strongly affect the dimensions and the weights of ... [more ▼]

Formation flying is one of the most promising techniques for the future of astronomy and astrophysics from the space. The capabilities of the rockets strongly affect the dimensions and the weights of telescopes and instrumentation to be launched. Telescopes composed by several smallest satellites in formation flying, could be the key for build big space telescopes. With this aim, the ESA PROBA-3 mission will demonstrate the capabilities of this technology, maintaining two satellites aligned within 1 mm (longitudinal) when the nominal distance between the two is of around 144m. The scientific objective of the mission is the observation of the solar corona down to 1.08 solar radii. The Coronagraph Spacecraft (CSC) will observe the Sun, when the second spacecraft, the Occulter Spacecraft (OSC) will work as an external occulter, eclipsing to the CSC the sun disk. The finest metrology sub-systems, the Shadow Position Sensors (SPS) and the Occulter Position Sensor Emitters (OPSE) identifying respectively the CSC-Sun axis and the formation flying (i.e., CSC-OSC) axis will be considered here. In particular, this paper is dedicated to the test-bed for the characterization, the performance analysis and the algorithms capabilities analysis of the both the metrology subsystems. The test-bed is able to simulate the different flight conditions of the two spacecraft and will give the opportunity to check the response of the subsystems in the conditions as close as possible to the flight ones. [less ▲]

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See detailThe shadow position sensors (SPS) formation flying metrology
Focardi, Mauro; Thizy, Cédric ULg; Renotte, Etienne ULg

in Proceedings of SPIE (2016, June)

PROBA-3 [1] [2] is a Mission of the European Space Agency (ESA) composed of two formation-flying satellites, planned for their joint launch by the end of 2018. Its main purposes have a dual nature ... [more ▼]

PROBA-3 [1] [2] is a Mission of the European Space Agency (ESA) composed of two formation-flying satellites, planned for their joint launch by the end of 2018. Its main purposes have a dual nature: scientific and technological. In particular, it is designed to observe and study the inner part of the visible solar corona, thanks to a dedicated coronagraph called ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), and to demonstrate the in-orbit formation flying (FF) and attitude control capability of its two satellites. The Coronagraph payload on-board PROBA-3 consists of the following parts: the Coronagraph Instrument (CI) with the Shadow Position Sensor (SPS) on the Coronagraph Spacecraft (CSC), the Occulter Position Sensor (OPSE) [3] [4] and the External Occulting (EO) disk on the Occulter Spacecraft (OSC). The SPS subsystem [5] is one of the main metrological devices of the Mission, adopted to control and to maintain the relative (i.e. between the two satellites) and absolute (i.e. with respect to the Sun) FF attitude. It is composed of eight micro arrays of silicon photomultipliers (SiPMs) [6] that shall be able to measure, with the required sensitivity and dynamic range as asked by ESA, the penumbral light intensity on the Coronagraph entrance pupil. With the present paper we describe the testing activities on the SPS breadboard (BB) and Development Model (DM) as well as the present status and future developments of this PROBA-3 metrological subsystem. [less ▲]

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See detailALERBLOT: Interest of 2D Immunoblot for the diagnosis of allergy to wheat
BERTHOLET, Catherine ULg; GADISSEUR, Romy ULg; quinting, birgit et al

in Allergy (2016, June), 71

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See detailInstauration d'un trajet de réintégration multidisciplinaire au sein de l'Assurance Maladie belge : ombres et lumière
Mairiaux, Philippe ULg

in Archives des Maladies Professionnelles et de l'Environnement (2016, June), 77(3), 363

Le modèle dit de Sherbrooke développé par P. Loisel au Québec constitue le fondement des recommandations internationales en matière de programmes de retour au travail pour les travailleurs souffrant de ... [more ▼]

Le modèle dit de Sherbrooke développé par P. Loisel au Québec constitue le fondement des recommandations internationales en matière de programmes de retour au travail pour les travailleurs souffrant de lombalgie. Ce modèle a inspiré les recommandations belges et françaises (HAS 2013) en la matière. De nombreuses études explorent maintenant la possibilité d’une intervention précoce en milieu de travail – un des axes essentiels du modèle de Sherbrooke - dans d’autres problématiques de santé que la lombalgie, et notamment en cas de décompensation psychique. La combinaison d’une telle intervention avec les approches propres aux milieux de soin représente cependant un réel défi. Le programme de prévention secondaire de la lombalgie initié en Belgique en 2004 dans le cadre de l’assurance maladies professionnelles permet d’illustrer quelques-unes des difficultés à surmonter : information du public-cible (tout travailleur exposé à la manutention de charges et/ou aux vibrations corps-entier) et des médecins traitants concernés, mise en place d’une collaboration, jusque-là inexistante, entre médecins de revalidation et médecins du travail, sensibilisation des employeurs. Même la collaboration entre médecins se heurte à de sérieuses barrières. Elle implique en effet un dialogue et une relation de confiance entre le médecin traitant qui considère prioritairement la protection de son patient, le médecin du travail qui a à juger l’aptitude d’un travailleur pour une activité de travail définie et un médecin-conseil de la sécurité sociale dont la fonction centrale était encore récemment le contrôle du bien-fondé de l’arrêt de travail afin de préserver l’équilibre financier du système. La prévention de la désinsertion professionnelle devrait idéalement constituer un objectif commun à ces trois métiers médicaux mais il s’agit à l’évidence d’un chantier de longue haleine. La décision du gouvernement belge d’instaurer un trajet de réintégration multidisciplinaire au sein de l'Assurance Maladie pour tout assuré en arrêt-maladie depuis 3 mois a révélé, avant même sa mise en application prévue en 2016, les enjeux sous-jacents à un tel projet. Les négociations avec les partenaires sociaux ont abordé plusieurs questions. Veut-on promouvoir plus d’équité sociale, ou simplement limiter l’augmentation alarmante des dépenses d’invalidité ? L’entrée de l’assuré dans le trajet proposé va-t-elle se faire sur base volontaire, ou faut-il prévoir une sanction financière en cas de refus ? A quel médecin confier la direction du trajet ? Quelle place réserver au médecin du travail, et au médecin traitant ? Faut-il prévoir une responsabilisation financière de l’entreprise ou faire confiance à la bonne volonté des employeurs ? [less ▲]

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See detailEffect of chondroitin sulfate on soluble biomarkers of osteoarthritis: how to analyze and interpret the results from an open-label trial in unilateral knee osteoarthritis patients
Möller, I; Gharbi, Myriam; Martinez, H et al

in Annals of the Rheumatic Diseases (2016, June), 75(Suppl 2), 1167

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See detailAlignment and calibration of the ICON-FUV instrument: Development of a vacuum UV facility
Loicq, Jerôme ULg; Blain, Pascal ULg; Kintziger, Christian ULg et al

in Proceedings of SPIE (2016, June)

The optical calibration of the ICON-FUV instrument requires designing specific ground support equipment (GSE). The ICON-FUV instrument is a spectrographic imager that operates on two specific wavelengths ... [more ▼]

The optical calibration of the ICON-FUV instrument requires designing specific ground support equipment (GSE). The ICON-FUV instrument is a spectrographic imager that operates on two specific wavelengths in the UV (135.6 nm and 157 nm). All the operations have to be performed under vacuum UV light. The optical setup is based on a VUV monochromator coupled with a collimator that illuminates the FUV entrance slit. The instrument is placed on a manipulator providing fields pointing. Image quality and spectral properties can be then characterized for each field. OGSE, MGSE, optical calibration plan and vacuum alignment of the instrument are described. [less ▲]

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See detailRecent achievements on ASPIICS, an externally occulted coronagraph for PROBA-3.
Renotte, Etienne ULg; Denis, François ULg; Desselle, Richard ULg et al

in Proceedings of SPIE (2016, June)

This paper presents the current status of ASPIICS, a solar coronagraph that is the primary payload of ESA’s formation flying in-orbit demonstration mission PROBA-3. The “sonic region” of the Sun corona ... [more ▼]

This paper presents the current status of ASPIICS, a solar coronagraph that is the primary payload of ESA’s formation flying in-orbit demonstration mission PROBA-3. The “sonic region” of the Sun corona remains extremely difficult to observe with spatial resolution and sensitivity sufficient to understand the fine scale phenomena that govern the quiescent solar corona, as well as phenomena that lead to coronal mass ejections (CMEs), which influence space weather. Improvement on this front requires eclipse-like conditions over long observation times. The space-borne coronagraphs flown so far provided a continuous coverage of the external parts of the corona but their over-occulting system did not permit to analyse the part of the white-light corona where the main coronal mass is concentrated. The PROBA-3 Coronagraph System, also known as ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun) is designed as a classical externally occulted Lyot coronagraph but it takes advantage of the opportunity to place the external occulter on a companion spacecraft, about 150m apart, to perform high resolution imaging of the inner corona of the Sun as close as ~1.1 solar radii. The images will be tiled and compressed on board in an FPGA before being down-linked to ground for scientific analyses. ASPIICS is built by a large European consortium including about 20 partners from 7 countries under the auspices of the European Space Agency. This paper is reviewing the recent development status of the ASPIICS instrument as it is approaching CDR. [less ▲]

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See detailDe Reinach à Levinas : Hering et le réalisme phénoménologique
Boccaccini, Federico ULg

in Revue de théologie et de Philosophie (2016, June)

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