References of "Article"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailA probabilistic model for predicting the uncertainties of the humid stiction phenomenon on hard materials
Hoang Truong, Vinh ULg; Wu, Ling ULg; Paquay, Stéphane et al

in Journal of Computational & Applied Mathematics (in press)

Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the ... [more ▼]

Stiction is a major failure in microelectromechanical system (MEMS) devices in which two contacting surfaces can remain stuck together because of the adhesive forces. Due to the difference between the surfaces roughness and the adhesive force range, the real contact areas are usually smaller than the apparent one, resulting in a scatter in the adhesive forces. Consequently, the stiction is an uncertain phenomenon. In this work, we develop a probabilistic model to predict the uncertainties of stiction due to the capillary forces acting on stiff materials. This model contains two levels: at the deterministic level, the model can predict the pull-out adhesive contact forces for a given surface topology; at the probabilistic level, the model generates independent identically distributed surfaces on which the deterministic solution can be applied to evaluate the uncertainties related to the stiction phenomenon. [less ▲]

Detailed reference viewed: 67 (7 ULg)
Full Text
Peer Reviewed
See detailArsinoe II come dea attraverso le sue epiclesi cultuali
Caneva, Stefano ULg

in Athenaeum : Studii Periodici di Letteratura e Storia (in press), 103(1), 95-122

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con ... [more ▼]

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con l’eccezione dell’epiclesi esclusiva Philadelphos. Scopo della ricerca è 1) una valutazione delle strategie di inserimento della nuova dea nel pantheon tradizionale; 2) una riflessione sull’autoconsapevolezza degli antichi in relazione alla propria tradizione religiosa, per come essa si manifesta attraverso l’oculata manipolazione di un elemento essenziale nella definizione della divinità, qual è il nome divino. Un’Appendice elenca, in tre tabelle, tutte le denominazioni greche di Arsinoe II (esclusa Philadelphos), fornendo indicazioni sulla fonte, la sua collocazione spaziale e temporale e sulla divinità tradizionale di riferimento. [less ▲]

Detailed reference viewed: 63 (9 ULg)
Full Text
Peer Reviewed
See detailThin film superconducting shields
Claassen, John; Osofsky, Michael; Namburi, Devendra et al

in IEEE Transactions on Applied Superconductivity (in press)

To date, magnetic shields utilizing high-temperature superconductor materials mostly comprise bulk materials, usually shaped into a cylinder and then heat treated. We analyze the potential of thin-film ... [more ▼]

To date, magnetic shields utilizing high-temperature superconductor materials mostly comprise bulk materials, usually shaped into a cylinder and then heat treated. We analyze the potential of thin-film technology, whereby a layer of superconductor is deposited on a substrate, to fabricate magnetic shields. Films deposited on a curved surface are inevitably granular, leading to reduced critical current density compared with crystalline films. This limits the maximum field that can be screened. Granular films also have an enhanced penetration depth compared with the bulk value, which determines the maximum possible screening at applied fields below the maximum.We demonstrate the utility of a mutual inductancemeasurement to evaluate small flat test samples of a granular film for their potential as a shielding material in a more complex geometry. Thismeasurement predicts both themaximum magnetic field that can be screened and the residual leakage at fields below the maximum. The tested film was produced by the Electrophoretic deposition of YBCO on a silver substrate. The maximum screening field was comparable with that obtained for a similar film on a cylindrical substrate. We also show comparable results from a crystalline YBCO film. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailOn the accuracy of adults’ auditory perception of normophonic and dysphonic children’s personality.
Verduyckt, Ingrid; Remacle, Marc; Morsomme, Dominique ULg

in Logopedics, Phoniatrics, Vocology (in press)

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP ... [more ▼]

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP) children and children with VFN (N=10) on the basis of vowels and sentences. The auditory inferred profiles were compared to the actual personality of NP and VFN children. Positive and partly accurate inferences of VFN children’s personality were made on the basis of connected speech, while sustained vowels yielded negative and inaccurate inferences of personality traits of children with VFN. Dysphonic voice quality, as defined by the overall severity of vocal abnormality, conveyed inaccurate and low degrees of Extraversion. This effect was counterbalanced in connected speech by faster speaking rate that accurately conveyed higher degrees of Extraversion, a characteristic trait of VFN children’s actual personality. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailNew palaeobotanical data from the Lower Devonian of Mezquita de Loscos (Teruel Province, Spain)
Cascales - Miñana, Borja ULg; Rial, Gonzalo; Xue, Jinzhuang et al

in Historical Biology (in press)

Recent fieldwork has uncovered three new localities from the Lower Devonian of Mezquita de Loscos (Teruel Province, Spain) with further plant mega-fossils and the first record of micro-fossils. Such plant ... [more ▼]

Recent fieldwork has uncovered three new localities from the Lower Devonian of Mezquita de Loscos (Teruel Province, Spain) with further plant mega-fossils and the first record of micro-fossils. Such plant remains have been interpreted as belonging to a basal euphyllophyte, Taeniocrada-like stems, Hostinella genus and paired sporangia. Fourteen spore taxa were recovered, including Ambitisporites, Aneurospora, Brochotriletes, Chelinospora, Emphanisporites, Gneudnaspora and Retusotriletres, among others. New evidence confirms a Lochkovian age for this outcrop and suggests that the plant diversity was more complex than originally documented. © 2014 © 2014 Taylor & Francis. [less ▲]

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailA Stereocontrolled Synthesis of the Hydrophobic Moiety of Rhamnolipids
Menhour, Boudjema; Mayon, Patrick; Plé, Karen et al

in Tetrahedron Letters (in press)

Detailed reference viewed: 18 (2 ULg)
Full Text
Peer Reviewed
See detailLe manque de généralisation chez les enfants dysphasiques : une étude longitudinale
Leroy, Sandrine ULg; Parisse, Christophe; Maillart, Christelle ULg

in ANAE : Approche Neuropsychologique des Apprentissages chez l'Enfant (in press), 131

Usage-based theories postulate that development of linguistic system depends on a gradual generalization mechanism during which use of lexicalized language forms are little-by-little replaced by use of ... [more ▼]

Usage-based theories postulate that development of linguistic system depends on a gradual generalization mechanism during which use of lexicalized language forms are little-by-little replaced by use of abstract construction schemas. Several studies have shown limited morphosyntactic productivity in children with specific language impairment (SLI). In this longitudinal study, we have tested hypothesis according to which generalization would be hindered in children with SLI. [less ▲]

Detailed reference viewed: 33 (11 ULg)
Full Text
Peer Reviewed
See detailAtomistic account of structural and dynamical changes induced by small binders in the double helix of a short DNA
Fresch, Barbara ULg; Remacle, Françoise ULg

in Physical Chemistry Chemical Physics [=PCCP] (in press)

Detailed reference viewed: 28 (2 ULg)
Full Text
Peer Reviewed
See detailÉtude des contraintes mécaniques locomotrices chez le cheval
Noble, Prisca ULg; Collin, Bernard ULg; Denoix, Jean-Marie et al

in Annales de Médecine Vétérinaire (in press)

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some ... [more ▼]

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some equine diseased locomotor systems. In order to understand better the contraints in the equine locomotor dynamics, some investigations have been carried out. Moreover, some measurement methods, based on the mechanics of Newton, have been performed. This review shows the different measurement techniques and introduces the mechanical basis that are compulsory for the understanding of the equine locomotor apparatus functioning. [less ▲]

Detailed reference viewed: 161 (48 ULg)
Full Text
Peer Reviewed
See detailAIR VERSUS GROUND TRANSPORT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: EXPERIENCE IN A RURAL-BASED HELICOPTER MEDICAL SERVICE
MOENS, Didier ULg; Stipulante, Samuel ULg; Donneau, Anne-Françoise ULg et al

in European Journal of Emergency Medicine (in press)

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We ... [more ▼]

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We designed a prospective study involving patients with acute myocardial infarction aimed at the evaluation of the potential benefit of such primary HEMS interventions as compared with classical EMS ground transport. Methods & results This prospective study was conducted from July 1, 2007 to June 15, 2012. Successive patients with ST-segment elevation myocardial infarction (STEMI) eligible for percutaneous coronary intervention (PCI) were included. Simulated ground-based access times were computed using a digital cartographic program, allowing the estimation of healthcare system delay from call to admission to the catheterisation laboratory. During the study period, 4485 patients benefited from HEMS activations. Of these patients, 342 (8%) suffering from STEMI were transferred for primary PCI. Median primary response time time was 11 min (IQR: 8 - 14 min) using the helicopter and 32 min (25 – 44 min) using road transport. Median transport time using HEMS was 12 min (9 – 15 min) and 50 min (36 – 56 min) by road. The median system delay using HEMS was 52 min (45 – 60 min), while this time was 110 min (95 – 126 min) by road. Finally, the system delay median gain was 60 min (47 – 72 min). Conclusions Using HEMS in a rural region allows STEMI patients to benefit from appropriate rescue care with similar delays as those seen in urban patients. [less ▲]

Detailed reference viewed: 70 (16 ULg)
Full Text
Peer Reviewed
See detailContribution à un lexique épigraphique: "deltographéma"
Famerie, Etienne ULg

in Zeitschrift für Papyrologie und Epigraphik (in press)

Detailed reference viewed: 38 (5 ULg)
Full Text
Peer Reviewed
See detailTypus melancholicus et mélancolie : Synthèse théorique à partir d’un cas clinique
Englebert, Jérôme ULg; Stanghellini, Giovanni

in Encéphale (L') (in press)

Objective: The objective of this paper is to propose, starting from the description of a clinical emblematic case, a theoretical synthesis of the work of phenomenological psychopathology dedicated to ... [more ▼]

Objective: The objective of this paper is to propose, starting from the description of a clinical emblematic case, a theoretical synthesis of the work of phenomenological psychopathology dedicated to melancholia and typus melancholicus (TM), a clinical concept that describes the premorbid personality vulnerable to major depression (“melancholia” for the psychopathological tradition). Method: This is phenomenological analysis of a case study of melancolia, of its premorbid personality and pathogenic triggering situation. We adopt two main phenomenological keys to understanding the develpment of melancholia : role-identity theory and desynchronization theory. The former understands melancholia as a disorder of identity triggered by the loss of the social role with which one has previously over-identifed. The latter sees melancholia as the effect of the desynchronisation from the social environment that further develops into an inhibition of the conative–affective dynamics of life. We present the case of Jonas (64 years old), whose mother (94 years old) recently died. Before his mother’s death, Jonas’ life was entirely orchestrated by the caring for his mother and synchronized in time with this (e.g., he used to go to her house every 4 hours, took all his meals with her, etc.). Jonas, in addition to being hyper-synchronized and hyper-syntonic, fulfills all diagnostic criteria for TM, including “orderliness”, “conscientiousness”, “hyper/heteronomia” and “intolerance of ambiguity”. TM’s attach a disproportioned importance to their social roles (or external representations of identity) at the expense of their own ego-identity. Results: The passage from pre-morbid personality to melancholia is triggered by the death of Jonas’ mother that entails a profound depersonalization. Desynchronization and role loss cause Jonas fall into this severe depersonalization, whose core feature is the feeling of the loss of feeling. Conclusions: This original contribution demonstrates a clinical case can contribute to the construction and refinement of theoretical and conceptual frameworks (like princeps Tellenbach's studies). Over-synchronized tempo and over-identification with social role are emblematically in this case the two sides of the same coin. A parallelism can be established between synchronization (with the mother) and respect for the role at the expense of own identity. The clinical case of Jonas highlights a conceptual bridge between the model of melancholia as loss of social role and the model of melancholia as desynchronization. [less ▲]

Detailed reference viewed: 34 (8 ULg)
Full Text
Peer Reviewed
See detailThe Sceptical President: Václav Klaus' Influence on Czech Public Opinion on Climate Change
De Pryck, Kari; Gemenne, François ULg

in Climatic Change (in press)

Detailed reference viewed: 84 (11 ULg)
Full Text
Peer Reviewed
See detailAll for a container: Technological mediation, transnational business and love affairs
Jedlowski, Alessandro ULg

in Transfers: Interdisciplinary Journal of Mobility Studies (in press)

This paper analyzes the articulation between mobility and technology within life trajectories marked by migration, exile and the search for economic achievement. It does so by focusing on a Nigerian ... [more ▼]

This paper analyzes the articulation between mobility and technology within life trajectories marked by migration, exile and the search for economic achievement. It does so by focusing on a Nigerian couple’s (attempted) itinerary of return migration from Italy to Nigeria, and on the role played by a specific transport technology, the shipping container, within this process. It highlights how, throughout the itinerary that brings the container from Italy to Nigeria, its social meaning and value become the center of a series of tense interactions, in which different conceptions of family hierarchies, contrasting spiritual beliefs, as well as diverging imaginaries about transnational mobility, migration and life abroad come to the fore, and provoke radical transformations in the life of the people involved in the itinerary of the container itself [less ▲]

Detailed reference viewed: 25 (0 ULg)
Full Text
See detailLevallois et Gravettien
Otte, Marcel ULg; Noiret, Pierre ULg

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]

Detailed reference viewed: 46 (14 ULg)
Full Text
Peer Reviewed
See detailAnother Generalization of Abelian Equivalence: Binomial Complexity of Infinite Words (long version)
Rigo, Michel ULg; Salimov, Pavel

in Theoretical Computer Science (in press)

The binomial coefficient of two words $u$ and $v$ is the number of times $v$ occurs as a subsequence of $u$. Based on this classical notion, we introduce the $m$-binomial equivalence of two words refining ... [more ▼]

The binomial coefficient of two words $u$ and $v$ is the number of times $v$ occurs as a subsequence of $u$. Based on this classical notion, we introduce the $m$-binomial equivalence of two words refining the abelian equivalence. Two words $x$ and $y$ are $m$-binomially equivalent, if, for all words $v$ of length at most $m$, the binomial coefficients of $x$ and $v$ and respectively, $y$ and $v$ are equal. The $m$-binomial complexity of an infinite word $x$ maps an integer $n$ to the number of $m$-binomial equivalence classes of factors of length $n$ occurring in $x$. We study the first properties of $m$-binomial equivalence. We compute the $m$-binomial complexity of two classes of words: Sturmian words and (pure) morphic words that are fixed points of Parikh-constant morphisms like the Thue--Morse word, i.e., images by the morphism of all the letters have the same Parikh vector. We prove that the frequency of each symbol of an infinite recurrent word with bounded $2$-binomial complexity is rational. [less ▲]

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailEnzymatic hydrolysis of softwood and hardwood regenerated celluloses
Jacquet, Nicolas ULg; Maniet, Guillaume ULg; Richel, Aurore ULg et al

in Current Chemical Biology (in press)

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for ... [more ▼]

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for hardwood regenerated cellulose (HRC) and 90% for softwood regenerated cellulose (SRC). Crystallinity indices from X-Ray diffraction patterns were used to measure hydrolysis rate of crystalline and amorphous regions. Addition of β-glucosidase to the enzymatic complex of Trichoderma reesei was confirmed to enhance yields of hydrolysis. [less ▲]

Detailed reference viewed: 28 (5 ULg)
Full Text
Peer Reviewed
See detailOne injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's knee
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in The Journal of sports medicine and physical fitness (in press)

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]

Detailed reference viewed: 79 (17 ULg)
Full Text
Peer Reviewed
See detailSur Capitalisme, désir et servitude. Lettre à Frédéric Lordon
Pieron, Julien ULg

in Dissensus (in press), 6(printemps 2014),

Detailed reference viewed: 23 (4 ULg)
Full Text
Peer Reviewed
See detailExpression microarray as a tool to identify candidate blood biomarkers in horses suffering from inflammatory airway disease
Ramery, Eve ULg; Fraipont, Audrey ULg; Art, Tatiana ULg et al

in Veterinary Clinical Pathology (in press)

Background: Inflammatory airway disease (IAD) affects performance and well-being in horses. Diagnosis is primarily reached by bronchoalveolar lavage (BAL) cytology but this is invasive and requires ... [more ▼]

Background: Inflammatory airway disease (IAD) affects performance and well-being in horses. Diagnosis is primarily reached by bronchoalveolar lavage (BAL) cytology but this is invasive and requires sedation. Objectives: The purpose of this study was to identify candidate blood biomarkers of IAD using species-specific expression microarrays. Methods: Horse Gene Expression Microarrays were used to investigate global mRNA expression in circulating leukocytes from healthy and IAD-affected standardbreds and endurance horses. Results: Nine genes were significantly differentially regulated in standardbreds and 61 in endurance horses (P < 0.001). These genes were mainly related to inflammation (eg. ALOX15B, PLA2G12B and PENK), oxidant/antioxidant balance (eg. DUOXA2 and GSTO1-1) and stress (eg. V1aR, GRLF1, Homer-2 and MAOB). DUOXA2, ALOX15B, PLA2G12B, MAOB and GRLF1 variations of expression were further validated by RT-qPCR. The deregulation of the oxidant/antioxidant balance was demonstrated at the protein level by an increase of glutathione peroxidase (GPx) activity in heparinised whole blood of IAD-affected standardbreds (P = 0.0025) and endurance horses (P = 0.0028). There was good correlation (r = 0.7354) between BAL neutrophil percentage and whole blood GPx activity in all horses. Conclusions: There is accumulating evidence that, even when systemic clinical signs are not evident, circulating leukocyte gene expression can reflect responses of other tissues, leading to potential diagnostic applications in the future. Although not specific for IAD, whole blood GPx activity appears to reflect BAL neutrophil percentage. This finding should be further assessed by testing a larger number of horses. [less ▲]

Detailed reference viewed: 57 (8 ULg)
Full Text
Peer Reviewed
See detailA Parallel Processing Approach to Dynamic Simulations of Combined Transmission and Distribution Systems
Aristidou, Petros ULg; Van Cutsem, Thierry ULg

in International Journal of Electrical Power & Energy Systems (in press)

Simulating a power system with both transmission and distribution networks modeled in detail is a huge computational challenge. In this paper, a Schur-complement-based domain decomposition algorithm is ... [more ▼]

Simulating a power system with both transmission and distribution networks modeled in detail is a huge computational challenge. In this paper, a Schur-complement-based domain decomposition algorithm is proposed to provide accurate, detailed dynamic simulations of such systems. The simulation procedure is accelerated with the use of parallel programming techniques, taking advantage of the parallelization opportunities inherent to domain decomposition algorithms. The proposed algorithm is general, portable and scalable on inexpensive, shared-memory, multi-core machines. A large-scale test system is used for its performance evaluation. [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
Peer Reviewed
See detailExploring the major depletions of conodont diversity during the Triassic
Martínez-Pérez, Carlos; Cascales - Miñana, Borja ULg; Plasencia, Pablo et al

in Historical Biology (in press)

In this paper, we show that the Triassic fossil record reflects just two great depletions of conodont diversity before the Rhaetian, which occurred in the Smithian (Olenekian, Early Triassic) and in the ... [more ▼]

In this paper, we show that the Triassic fossil record reflects just two great depletions of conodont diversity before the Rhaetian, which occurred in the Smithian (Olenekian, Early Triassic) and in the Julian (Carnian, Late Triassic). By exploring this context, our results highlighted that they respond to different origination-extinction dynamics. Thus, while the Smithian diversity depletion can be interpreted as a consequence of elevated extinction, the Julian diversity depletion was triggered by fluctuations in origination regime. This evidence suggests that, despite the role of extinction on diversity losses, conodonts suffered crucial changes on the origination regimes during the Late Triassic which triggered these events. Notwithstanding, our results indicate that the end-Triassic diversity depletion of conodonts was produced by background extinction levels in a context of lower origination. This suggests that several biological factors, rather than a unique, environmental and/or cyclic cause, could have influenced the evolutionary history of conodonts during the Triassic. © 2014 © 2014 Taylor & Francis. [less ▲]

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailRéduire l’altérité au travers des processus de traduction et de représentation
Leclercq, Bruno ULg; Smette, Bernard ULg

in Doctorales. Revue LLA-SHS de Montpellier (in press)

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity ... [more ▼]

WVO Quine questions the « myth » of an ideal realm of shared meanings which every national language would express in its own way. Against the hope of transparent translations, he insists on the necessity for building equivalences from one language to another through a strategy of reducing the differences in rationality among nations as much as possible. According to Quine, otherness is not insuperable impediment to meeting/encounter and mutual understanding ; by throwing our conceptual schemes on the other communities’ uses/practices – which of course involves some symbolic violence – gaps can always been narrowed. Similarly E. Laclau questions the traditional conception of political representation, which is seen as the transparent process of transmitting someone’s will or interests on another level. For this ideal conception of representation, Laclau substitutes a pragmatic conception which takes in account the irreducible gap between the actors as well as the constitutive opacity of the process of representation : the subject’s will is constituted within the process of representation and through the representative’s productive role. In order to be transposed at the decision-making level, the subject’s interests must be translated by the representative as well as be negotiated with the other represented interests. This implies that the initial will undergoes some identity transformations. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailIdentification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people.
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Couffignal, Vincent et al

in Clinical physiology and functional imaging (in press)

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]

Detailed reference viewed: 65 (5 ULg)
Full Text
Peer Reviewed
See detailAcyclic, connected and tree sets
Berthé, Valérie; De Felice, Clelia; Dolce, Francesco et al

in Monatshefte für Mathematik (in press)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailDynamic single-cell analysis of Saccharomyces cerevisiae under process perturbation: comparison of different methods for monitoring the intensity of population heterogeneity
Delvigne, Frank ULg; Baert, Jonathan ULg; Gofflot, Sébastien et al

in Journal of Chemical Technology & Biotechnology (in press)

BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context ... [more ▼]

BACKGROUND: Single cell biology has attracted a lot of attention these past few years and has led to numerous fundamental results pointing out the heterogeneity of clonal cell populations. In this context, microbial phenotypic heterogeneity under bioprocessing conditions needs to be further investigated. In this study, yeast based processes have been investigated by using on-line flow cytometry in combination with a fluorescent transcriptional reporter (GFP) and viability fluorescence tags (propidium iodide, PI). Methods aiming at expressing the dispersion of these fluorescence tags among the yeast populations have been investigated for different bioreactor operating conditions. RESULTS: Yeast viability was determined on the basis of PI uptake. Segregation between PI negative and positive subpopulations could be efficiently quantified on the basis of the mean-to-median ratio or the amplitude of the interquartile range. On the other hand, the same quantification could not be made for the segregation occurring at the level of GFP synthesis. Indeed, when cells were exposed to sub-lethal or mild stresses (such as in scale-down reactors) two GFP subpopulations could be visualized by real-time FC, but quantification by one of the above-mentioned methods was not possible. CONCLUSIONS: Yeast population heterogeneity was observed in representative bioreactor operating conditions. Difficulties for the determination of segregation at the level of GFP synthesis point out the fact that one needs to understand the segregation mechanisms for the applied fluorescent reporters, to judge whether simple mathematical tools may be applied or if more sophisticated computational tools are needed for the quantification of the microbial population segregation. [less ▲]

Detailed reference viewed: 48 (6 ULg)
Full Text
Peer Reviewed
See detailModulating effect of COMT Val158Met polymorphism on interference resolution during a working memory task
Jaspar, Mathieu ULg; DIDEBERG, Vinciane ULg; Bours, Vincent ULg et al

in Brain & Cognition (in press)

Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates ... [more ▼]

Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates underlying inhibitory processes and updating in working memory (WM). In an event-related functional magnetic resonance imaging (fMRI) study, we administered a modified version of the Sternberg probe recency task (Sternberg, 1966) to 43 young healthy volunteers, varying the level of interference across successive items. The task was divided into two parts (high vs. low interference) to induce either proactive or reactive control processes. The participants were separated into three groups according to their COMT Val158Met genotype [Val/Val (VV); Val/Met (VM); Met/Met (MM)]. The general aim of the study was to determine whether COMT polymorphism has a modulating effect on the neural substrates of interference resolution during WM processing. Results indicate that interfering trials were associated with greater involvement of frontal cortices (bilateral medial frontal gyrus, left precentral and superior frontal gyri, right inferior frontal gyrus) in VV homozygous subjects (by comparison to Met allele carriers) only in the proactive condition of the task. In addition, analysis of peristimulus haemodynamic responses (PSTH) revealed that the genotype-related difference observed in the left SFG was specifically driven by a larger increase in activity from the storage to the recognition phase of the interfering trials in VV homozygous subjects. These results confirm the impact of COMT genotype on inhibitory processes during a WM task, with an advantage for Met allele carriers. Interestingly, this impact on frontal areas is present only when the level of interference is high, and especially during the transition from storage to recognition in the left superior frontal gyrus. [less ▲]

Detailed reference viewed: 38 (1 ULg)
Full Text
Peer Reviewed
See detailRéflexions autour des principes de rééducation proposés aux enfants dysphasiques
Maillart, Christelle ULg; Desmottes, Lise ULg; Prigent, Gaïd ULg et al

in ANAE : Approche Neuropsychologique des Apprentissages chez l'Enfant (in press), 131

This paper addresses the principles used in efficient language intervention. These principles will be examined in the light of recent data in typical and atypical language development. Particular ... [more ▼]

This paper addresses the principles used in efficient language intervention. These principles will be examined in the light of recent data in typical and atypical language development. Particular attention will be given to repetition and variability, in link with recent theoretical framework about language development. [less ▲]

Detailed reference viewed: 60 (22 ULg)
Full Text
Peer Reviewed
See detailLe Mur et le masque. À propos de Banksy.
Saint-Amand, Denis ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Detailed reference viewed: 44 (3 ULg)
Full Text
Peer Reviewed
See detailGender effect on the scapular 3D posture and kinematic in healthy subjects
Schwartz, Cédric ULg; Croisier, Jean-Louis ULg; Rigaux, Elise et al

in Clinical Physiology and Functional Imaging (in press)

Populations considered for shoulder analysis are often composed of various ratios of men and women. It is consequently hypothesized that gender has no significant effect on the joint kinematic. However ... [more ▼]

Populations considered for shoulder analysis are often composed of various ratios of men and women. It is consequently hypothesized that gender has no significant effect on the joint kinematic. However the literature reports, for the shoulder, differences in the range of motion between genders. The specific influence of gender on the scapula-thoracic kinematics has not been studied yet. The dominant shoulder of two populations of men and women composed of 11 subjects each were evaluated in three dimensions for three distinct motions: flexion in the sagittal plane, abduction in the frontal plane and gleno-humeral internal/external rotation with the arm abducted at 90°. Posture, kinematics and range of motion were studied separately. For flexion and abduction and with regard to the scapular kinematic, external rotation were significantly larger for women than men. The differences were of at least 5° at 120° of humeral elevation. Upward rotations were identical. Women also showed larger average active humero-thoracic range of motion. The mean differences were of 13°, 7°, 12° and 5° for abduction, flexion, internal rotation and external rotation, respectively. No difference was observed between the scapular resting positions of both populations. The observed differences concerning both the scapular and humeral patterns would indicate that the shoulder behavior of men and women should not be expected to be similar. [less ▲]

Detailed reference viewed: 57 (12 ULg)
Full Text
Peer Reviewed
See detailCan we identify patients with high risk of osteoarthritis progression who will respond to treatment ? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, Olivier ULg; Cooper, C; Arden, N et al

in Drugs & Aging (in press)

Osteoarthritis is a syndrome affecting a variety of patient profiles. A European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the European Union Geriatric Medicine ... [more ▼]

Osteoarthritis is a syndrome affecting a variety of patient profiles. A European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the European Union Geriatric Medicine Society working meeting explored the possibility of identifying different patient profiles in osteoarthritis. The risk factors for the development of osteoarthritis include systemic factors (e.g., age, sex, obesity, genetics, race, and bone density) and local biomechanical factors (e.g., obesity, sport, joint injury, and muscle weakness); most also predict disease progression, particularly joint injury, malalignment, and synovitis/effusion. The characterization of patient profiles should help to better orientate research, facilitate trial design, and define which patients are the most likely to benefit from treatment. There are a number of profile candidates. Generalized, polyarticular osteoarthritis and local, monoarticular osteoarthritis appear to be two different profiles; the former is a feature of osteoarthritis comorbid with inflammation or the metabolic syndrome, while the latter is more typical of post-trauma osteoarthritis, especially in cases with severe malalignment. Other biomechanical factors may also define profiles, such as joint malalignment, loss of meniscal function, and ligament injury. Early- and late-stage osteoarthritis appear as separate profiles, notably in terms of treatment response. Finally, there is evidence that there are two separate profiles related to lesions in the subchondral bone, which may determine benefit from bone-active treatments. Decisions on appropriate therapy should be made considering clinical presentation, underlying pathophysiology, and stage of disease. Identification of patient profiles may lead to more personalized healthcare, with more targeted treatment for osteoarthritis. [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailApplication of Steam Explosion as Pretreatment on Lignocellulosic Material: A Review
Jacquet, Nicolas ULg; Maniet, Guillaume ULg; Vanderghem, Caroline ULg et al

in Industrial & Engineering Chemistry Research (in press)

Steam explosion is a thermo-mechanicochemical pretreatment which allows the breakdown of lignocellulosic structural components by the action of heating, formation of organic acids during the process, and ... [more ▼]

Steam explosion is a thermo-mechanicochemical pretreatment which allows the breakdown of lignocellulosic structural components by the action of heating, formation of organic acids during the process, and shearing forces resulting in the expansion of the moisture. Two distinct stages compose the steam-explosion process: vapocracking and explosive decompression which include modification of the material components: hydrolysis of hemicellulosic components (mono- and oligosaccharides released), modification of the chemical structure of lignin, and modification of the cellulose crystallinity index, etc. These effects allow the opening of lignocellulosic structures and influence the enzymatic hydrolysis yield of the material. [less ▲]

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailConnections between the design tool, design attributes, and user preferences in early stage design
Häggman, Anders; Tsai, Geoff; Elsen, Catherine ULg et al

in Journal of Mechanical Design (in press)

Gathering user feedback on provisional design concepts early in the design process has the potential to reduce time-to-market and create more satisfying products. Among the parameters that shape user ... [more ▼]

Gathering user feedback on provisional design concepts early in the design process has the potential to reduce time-to-market and create more satisfying products. Among the parameters that shape user response to a product, this paper investigates how design experts use sketches, physical prototypes, and computer-aided design (CAD) to generate and represent ideas, as well as how these tools are linked to design attributes and multiple measures of design quality. Eighteen expert designers individually addressed a two-hour design task using only sketches, foam prototypes, or CAD. It was found that prototyped designs were generated more quickly than those created using sketches or CAD. Analysis of 350 crowdsourced responses to the resulting designs showed that those created as prototypes were perceived as more novel, more aesthetically pleasing, and more comfortable to use. It was also found that designs perceived as more novel tended to fare poorly on all other measured qualities. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailPractical management of Chronic Myeloid Leukemia in Belgium
Benghiat, FS.; Beguin, Yves ULg; Dessars, B. et al

in Belgian Journal of Hematology (in press)

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]

Detailed reference viewed: 55 (8 ULg)
Full Text
Peer Reviewed
See detailPer una edizione integrale e analitica dell'incipit della Storia d'Italia di Francesco Guicciardini
Moreno, Paola ULg

in Laboratoire Italien : Politique et Société (in press)

Detailed reference viewed: 40 (2 ULg)
Full Text
Peer Reviewed
See detailSiting Controversies Analysis: Framework and Method for Questioning the Procedure
Rossignol, Nicolas ULg; Parotte, Céline ULg; Joris, Geoffrey ULg et al

in Journal of Risk Research (in press)

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]

Detailed reference viewed: 37 (3 ULg)
Full Text
Peer Reviewed
See detailLe phénotype d’Akhenaton ; revue critique entre canons artistiques et expression pathologique.
JEDIDI, Zayd ULg; JEDIDI, Haroun ULg; LAVEAUX, Elisabeth et al

in Revue Médicale de Liège (in press)

Of all the royal families of ancient or modern fame, few are as iconic as the eighteenth dynasty of pharaohs of the New Kingdom of Egypt, whose opulence and deeds we are still familiar to nearly 3,500 ... [more ▼]

Of all the royal families of ancient or modern fame, few are as iconic as the eighteenth dynasty of pharaohs of the New Kingdom of Egypt, whose opulence and deeds we are still familiar to nearly 3,500 years after their time. Tenth pharaoh of this dynasty and father of Tutankhamun, Akhenaten (Amenhotep/Amenhotep IV) still fascinates Egyptologists and history lovers through the many questions surrounding his atypical rule. One of the most striking aspects of the so-called Amarna period concerns the representations of the pharaoh himself, very confusing compared to the traditional iconography of the New Kingdom. These intriguing portraits of Pharaoh raised a whole lot of medical assumptions, more or less substantiated. We review here the main theories developed throughout history. [less ▲]

Detailed reference viewed: 23 (7 ULg)
Full Text
Peer Reviewed
See detailInfluence of process operating conditions on solvent thermal and oxidative degradation in post-combustion CO2 capture
Léonard, Grégoire ULg; Crosset, Cyril; Toye, Dominique ULg et al

in Computers & Chemical Engineering (in press)

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent ... [more ▼]

///Document soumis, la révision doit encore être faite./// The CO2 post-combustion capture with amine solvents is modeled as a complex system interconnecting process energy consumption and solvent degradation and emission. Based on own experimental data, the kinetics of monoethanolamine degradation is included into a model of the CO2 capture process. The influences of operating conditions and flowsheet improvements on solvent loss and process energy requirement are quantified and validated with pilot plant data. Oxidative degradation in the absorber is identified as the major cause of solvent loss. On the contrary, thermal degradation does not appear as a major concern. Finally, this study leads to a decrease by 10% of the process exergy requirement along with a reduction by 11% of the solvent loss, all that by using a single model. Thus, this model provides a practical tool to minimize both the energy requirement and the solvent degradation by the design of large-scale CO2 capture units. [less ▲]

Detailed reference viewed: 28 (3 ULg)
Full Text
Peer Reviewed
See detailLe point sur l’évaluation de la force des muscles respiratoires
Kellens, Isabelle ULg; Crielaard, Jean-Michel ULg

in Revue Médicale de Liège (in press)

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect ... [more ▼]

The strength of respiratory muscles is crucial for quality of life, especially for patients with lung or neurological disorders. Several methods can be used to assess them: i.e direct or indirect, voluntary or involuntary. The conventional spirometry method assesses indirectly the respiratory function by measuring maximum inspiratory and expiratory pressure, which reflects the coordination of all respiratory muscles. Techniques of magnetic and electrical stimulation can detect a specific muscle dysfunction, independently of the patient's motivation, however they are invasive methods as measurements are made in the esophagus and stomach. The voluntary techniques are generally non-invasive and require patient's cooperation. Measures of respiratory muscle strength, coupled to a conventional spirometry, can predict the development of ventilatory support in patients at risk, and may be useful during weaning from mechanical ventilation in intensive care units. [less ▲]

Detailed reference viewed: 156 (38 ULg)
Full Text
Peer Reviewed
See detailArrêts sur images – usages et pratiques du photogramme
Thonon, Jonathan ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Le photogramme est, au cinéma, la plus petite unité de prise de vue. Image fixe, unité élémentaire du film, le photogramme forme la cellule figée d’un mouvement qui se reconstitue sous l’effet d’un ... [more ▼]

Le photogramme est, au cinéma, la plus petite unité de prise de vue. Image fixe, unité élémentaire du film, le photogramme forme la cellule figée d’un mouvement qui se reconstitue sous l’effet d’un défilement réglé (24 photogrammes/seconde) par le dispositif technique du cinéma. Image paradoxale en ce qu’elle reste invisible au spectateur malgré sa force iconique, le photogramme trouve cependant, dans le flux qui le conduit insensiblement à la disparition, certaines zones de visibilité qui en révèlent le caractère à la fois fragile et intensif. Nous allons donc envisager certaines pratiques ou certains usages du photogramme cinématographique, tout en essayant de dégager, au départ de ces pratiques, les éléments d’une théorie du photogramme, que Roland Barthes et Sylvie Pierre appelaient déjà de leurs vœux. Des protos-photogrammes et de leur usage scientifique chez Muybridge et Marey, aux usages artistiques contemporains, en passant par des pratiques publicitaires, promotionnelles ou analytiques, nous allons voir que le photogramme reste un objet singulier. [less ▲]

Detailed reference viewed: 38 (5 ULg)
Full Text
Peer Reviewed
See detailLes recettes de l’Autre. De la transmission des savoirs (et savoir-faire) féminins en contexte migratoire.
Mescoli, Elsa ULg

in Hommes & Migrations (in press)

La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont ... [more ▼]

La plupart des études sur la connexion entre alimentation et migration sont assez récentes. Elles mettent tout d’abord en évidence le fait que, lors d’un déplacement, les individus ou les groupes sont confrontés à des styles alimentaires différents. Ces recherches s’engagent alors à vérifier dans quelle mesure cette rencontre défie l’identité individuelle (Cardona, 2004; Crenn, 2004; Spiro, 1955) et quelles pratiques elle engage afin de la préserver (Hage, 1997; Beyers, 2008; Diner and Diner, 2009). L’attention est ainsi portée au contexte domestique dans lequel les familles issues de la migration préparent leurs repas et, potentiellement, définissent leur appartenance culturelle. Une deuxième direction entreprise par ces études, concerne par contre l’espace public : par exemple, les ainsi dits « restaurants ethniques » font l’objet de nombreuses recherches qui visent cette fois à analyser la consommation de l’ « exotique » de la part des membres de la population majoritaire (Hassoun & Raulin, 1995; Régnier, 2005). Ces deux dimensions principales sont rarement abordées dans leur superposition, fait qui laisse dans l’ombre des dynamiques pareillement pertinentes. Notamment, nous pourrions relever les enjeux liés à la préparation de nourriture conçue comme pratique du quotidien destinée à être exportée en contexte non-domestique et offerte à des individus qui, non seulement ne font pas partie de la famille de ceux qui cuisinent, mais sont aussi associés à une appartenance culturelle différente. L’étude de ces enjeux amène à constater que la définition active de soi au travers de la pratique culinaire s’entremêle à la volonté d’en transmettre une image aux autres. En particulier, lorsqu’on adopte une perspective de genre et que l’on focalise l’attention sur les femmes migrantes, nous sommes amenés à noter comment un de ces savoir-faire qui constituent des potentiels dispositifs de domestication (Rogers, 1981) se transforme en instrument de visibilité, et ainsi de participation, dans l’espace public. Dans cet article, afin de mettre en évidence la complexité de ces dynamiques, je présenterai en clef comparative des exemples collectés dans le cadre de mes recherches autour du lien entre alimentation et migration. J’analyserai les pratiques culinaires exercées en contexte public d’un côté par un groupe de femmes marocaines résidentes en Italie, de l’autre par certaines femmes italiennes résidentes en Belgique. La comparaison des choix des femmes, faits en fonction des destinataires mais aussi en réponse aux différents contextes sociopolitiques dans lesquels certaines manifestations culinaires prennent la forme de « rencontres interculturelles », permettra de donner un aperçu sur la façon dont les femmes considérées s’assurent une place active dans l’espace vécu. Le texte sera illustré par des images collectées durant l’ethnographie. [less ▲]

Full Text
Peer Reviewed
See detailReduced Order Analysis of Aeroelastic Systems with Freeplay using an Augmented Modal Basis
Silva, Gustavo H. C.; Dal Ben Rossetto, Gustavo; Dimitriadis, Grigorios ULg

in Journal of Aircraft (in press)

Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on ... [more ▼]

Freeplay in aircraft control surface actuators is a common source of nonlinearity that can cause undesirable aeroelastic phenomena and, as a consequence, certification authorities place strict limits on the size of the deadband gaps of actuators. In recent years many authors have worked on determining the effects of freeplay on the dynamic behavior of aeroelastic systems; these efforts have yielded significant improvements in the understanding of the phenomena, but have concentrated on simple models. Investigations of industry-relevant aeroelastic models of complete aircraft with freeplay in the actuators have been much rarer, the main difficulty being the selection of an appropriate modal basis that can represent the full range of possible dynamic phenomena. This work presents a novel implementation of the residual vectors approach to create consistent and numerically stable reduced order models suitable for industrial-standard aeroelastic models of aircraft. The methodology relies on the piecewise linear nature of freeplay to create a single reduction basis that represents the dynamics of the system both inside and outside the freeplay deadband gap. The method is demonstrated on an Embraer generic test bench aircraft, showing that the resulting reduced order model is efficient and effective. Nonlinear analysis is carried out using equivalent linearization as well as time integrations of the full nonlinear system. It is shown that, while equivalent linearization is an indispensable tool for a preliminary mapping of the main aeroelastic instabilities, the time integration-based nonlinear analysis is an essential complementary tool to confirm the characteristics of the system behavior. [less ▲]

Detailed reference viewed: 47 (4 ULg)
Peer Reviewed
See detailPérils de la copie : les cas de l’Estoire del Saint Graal, du Merlin et de la Suite Vulgate
Combes, Annie ULg

in Cahiers de Civilisation Médiévale (in press)

Detailed reference viewed: 37 (1 ULg)
Full Text
Peer Reviewed
See detailChild labour, Agency and Family dynamics: The Case of Mining in Katanga (DRC)
Andre, Géraldine ULg; Godin, Marie

in Childhood (in press)

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into ... [more ▼]

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into this flourishing business sector, and among them, children. At first glance, one could see children in the mining sector mainly as victims entangled in the flows of raw materials of unbridled capitalism. But this paper aims to look at the often unconceivable, and as a result neglected, social agency of children even when they are involved in stigmatized and prohibited types of child labour. To do so, it relies on the results of a socio-anthropological collective research project on children’s mining activities which was carried out in a small locality called La Ruashi in the city of Lubumbashi (Province of Katanga). The article aims to provide a more comprehensive understanding of what is often normatively only labelled as ‘child labour’ by looking at different spheres of social relations within which children are embedded. Examining the set of social interactions that children have with their families, the broader community and their ‘peers’, several ‘family portraits’ are offered, highlighting a heterogeneity of social interpretations regarding this ‘new’ form of child work. It will be shown that for families from middle-class background, this kind of work is often socially disruptive, at the forefront of inter-generational conflict. As for families from lower classes, social changes induced by children’s mining activities are often better incorporated into the family habitus. Common social changes encountered in all families irrespective of class belonging will also be portrayed, showing the transversal societal impact these ‘new’ forms of child economic activities can provoke at a micro level. [less ▲]

Detailed reference viewed: 51 (10 ULg)
Full Text
Peer Reviewed
See detailTransposability of pedotransfer functions for estimating water retention of Algerian soils
Touil, Sami; Degré, Aurore ULg; Chabaca, Mohamed Nacer

in Desalination and Water Treatment (in press)

Testing the efficiency of a pedotransfer function (PTF) outside of its development data-set is one of the best ways for assessing its robustness. An important question which remains unanswered is how ... [more ▼]

Testing the efficiency of a pedotransfer function (PTF) outside of its development data-set is one of the best ways for assessing its robustness. An important question which remains unanswered is how transposable are PTFs to other agropedoclimatic contexts? Models developed and validated in a particular pedoclimatic context have been relatively little tested in other contexts. Particularly, no studies have been conducted until now to evaluate the PTFs for Algerian soils. In this study, eight (8) PTFs most frequently cited were considered. We used them to evaluate soil water retention at field capacity (FC) and wilting point (WP) on a set of 134 samples collected in the low Cheliff. The calculated Akaike information criterion and root mean square errors values showed that the Rawls, and Ghorbani Dashtaki et Homaee type 1 models were the best in estimation of soil water retention at FC (–709.795, 0.070 cm3 cm−3) and WP (–733.480, 0.064 cm3 cm−3). The poorer performances were presented by the PTFs developed on soils from Europe or United States where the organic matter values were much higher than the Algerian soils. However, the transposability of the PTFs formed from data spread from a wider area, produce more accurate predictions than those built from local data. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailA note on weighted likelihood and Jeffreys modal estimation of proficiency levels in polytomous item response models
Magis, David ULg

in Psychometrika (in press)

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this ... [more ▼]

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this note is to extend this result to polytomous item response models. First, a general condition is derived to ensure the perfect equivalence between these two estimators. Second, it is shown that this condition is fulfilled by two broad classes of polytomous models including, among others, the partial credit, rating scale, graded response and nominal response models. [less ▲]

Detailed reference viewed: 34 (6 ULg)
Full Text
Peer Reviewed
See detailA European survey on attitudes towards pain and end-of-life issues in locked-in syndrome
Demertzi, Athina ULg; Jox, Ralf J; Racine, Eric et al

in Brain Injury (in press)

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]

Detailed reference viewed: 126 (12 ULg)
Full Text
Peer Reviewed
See detailLes détournements de jeux vidéo par les joueurs : une incarnation du play
Barnabé, Fanny ULg

in RESET - Recherches en Sciences Sociales sur Internet (in press), (4),

Cet article a pour objectif d’analyser conjointement quatre pratiques de détournement du jeu vidéo par les joueurs (la rédaction de fanfictions, la réalisation de machinimas, le modding, et le speedrun ... [more ▼]

Cet article a pour objectif d’analyser conjointement quatre pratiques de détournement du jeu vidéo par les joueurs (la rédaction de fanfictions, la réalisation de machinimas, le modding, et le speedrun) en les envisageant comme des prolongements de l’expérience ludique. La forme des œuvres dérivées ainsi que les discours des joueurs qui les produisent seront étudiés parallèlement dans le but de mettre au jour en quoi ces pratiques renouvellent la conception même du jeu et lui ouvrent de nouveaux espaces. Ce travail se veut donc dans la lignée des play studies définies par Triclot (2011), qui envisagent le jeu vidéo non comme une forme figée mais comme une expérience. Précisément, trois points de passage assurant une continuité entre le jeu et ses réappropriations seront ici envisagés. Tout d’abord, la pratique du jeu vidéo et celle du détournement seront rapprochées en tant qu’elles se définissent toutes deux comme des performances (à la fois d’un point de vue technique et d’un point de vue interprétatif). Ensuite, nous envisagerons (notamment à l’aide du concept d’« affordance ») les différents moyens par lesquels les réappropriations peuvent – mimant le jeu – inciter leur récepteur à adopter une attitude ludique. Enfin, les recoupements entre la posture du joueur et celle du créateur de détournements suggèrent l’inclusion de ces pratiques de création dans un « play » généralisé. [less ▲]

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailConcentration, Activity and Biochemical Characterization of Myeloperoxidase in Fresh and Post-thaw equine semen and their Implication on Freezability
Ponthier, Jérôme ULg; Franck, Thierry ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (in press)

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and ... [more ▼]

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and to correlate these data with motilities in raw and thawed semen. Semen samples from five stallions were collected four times. Motilities were assessed in raw and thawed semen. MPO assays were performed in raw seminal plasma, raw sperm-rich pellet and thawed semen. Total and active MPO concentrations were, respectively, assayed by enzyme-linked immunosorbent assay and specific immunological extraction followed by enzymatic detection. MPO subunits present in semen were characterized by Western 3 blot. Purified active MPO was added in PBS and freezing extender to control its activity during freezing procedure. Differences between medians were determined using Kruskal– Wallis test, and correlations were determined using Spearman’s test for nonparametric data. Active MPO concentration was low in seminal plasma and thawed semen, but high in pellet (p = 0.0058), as the opposite relation was observed for total MPO concentration (p < 0.0001). In seminal plasma and post- thaw semen, inactive 86-kDa MPO precursor was mainly observed. Purified MPO activity was decreased in the extender (p = 0.0286). MPO activity in pellet was highly correlated with thawed progressive motility (r = 􏰑0.5576, p = 0.0086). Inac- tive MPO precursor and unknown low molecular weight inactive MPO precursor subunits explain low MPO activity in semen. Major MPO activity was observed in pellet, and post- thaw loss of activity is partially explained by MPO inactiva- tion in extender. Thawed semen motility was negatively correlated with MPO activity in pellet, becoming a potential freezability predictor. [less ▲]

Detailed reference viewed: 60 (10 ULg)
Full Text
Peer Reviewed
See detailNégocier une majorité politique et devenir bourgmestre en Belgique. Quelles influences des droits régionaux ?
Grandjean, Geoffrey ULg

in Revue Régionale de Droit [= RRD] (in press)

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la ... [more ▼]

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la négociation d’une majorité politique et la désignation des bourgmestres en Belgique ? Afin de répondre à cette question, des entretiens semi-directifs ont été réalisés avec plusieurs bourgmestres et échevin issus de communes localisées dans les trois Régions. Des différences entre Régions mais également au sein de celles-ci ont été relevées. Les dispositions relatives au mode de désignation du bourgmestre sont primordiales pour comprendre les dynamiques de négociations politiques. Au final, cet article tisse les liens entre les normes juridiques et les jeux des acteurs politiques. [less ▲]

Detailed reference viewed: 31 (11 ULg)
Full Text
Peer Reviewed
See detailCongenital jaundice in bovine aborted fetuses: an emerging syndrome in Southern Belgium
Delooz; Mori, M; Petitjean, T et al

in Transboundary and Emerging Diseases (in press)

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailL'intentionnalité cognitive et ses modes. Reinach critique de Brentano
Dewalque, Arnaud ULg

in Philosophie (in press)

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai ... [more ▼]

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai mon attention sur certaines divergences significatives entre Reinach et Brentano. Après quelques réflexions introductives (§§ 1-2), j’examinerai plus exactement les questions suivantes : quels sont les motifs théoriques qui ont conduit Reinach à s’écarter de la théorie brentanienne du jugement (§§ 3-4) ? Et que retenir de ses analyses aujourd’hui (§§ 5-6) ? [less ▲]

Detailed reference viewed: 34 (5 ULg)
Full Text
Peer Reviewed
See detailCionodendron and related lithostrotionid genera from the Mississippian of eastern Australia: systematics, stratigraphy and evolution
Denayer, Julien ULg; Webb, Gregory E.

in Alcheringa : An Australasian Journal of Paleontology (in press)

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailLa première interprétation heideggérienne de la Monadologie
Pieron, Julien ULg

in Philosophie (in press)

Detailed reference viewed: 50 (12 ULg)
Full Text
Peer Reviewed
See detailBifix codes and interval exchanges
Berthé, Valérie; De Felice, Clelia; Dolce, Francesco et al

in Journal of Pure and Applied Algebra (in press)

Detailed reference viewed: 9 (0 ULg)
Full Text
Peer Reviewed
See detailInternal encoding style and schizotypy: towards a conceptually-driven account of positive symptoms
Belayachi, Sanaa ULg; Laloyaux, Julien ULg; Laroi, Frank ULg et al

in Journal of Personality Disorders (in press)

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven ... [more ▼]

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven and conceptually-driven processing. A chronic imbalance between these two sources of stimulus encoding is likely to be maladaptive and could underlie cognitive and behavioral disturbances similar to that observed in schizotypy, especially if the balance is tipped too far towards conceptually-driven processing (i.e., Internal encoding style). This study aimed to examine the relationships between encoding style and various dimensions of schizotypy, by using a questionnaire that evaluates the extent to which pre-existing schemata (versus cues from the outside world) affect encoding processes. Consistent with previous findings, our results revealed that both Cognitive-Perceptual and Disorganization dimensions were related to an internal mode of encoding, suggesting that individuals with these features may be characterized by a disposition to biases at early stages of encoding. [less ▲]

Detailed reference viewed: 51 (4 ULg)
Full Text
Peer Reviewed
See detailGenetic parameters for mid-infrared methane indicators based on milk fatty acids in dairy cows
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

in Journal of Applied Animal Research (in press)

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not ... [more ▼]

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not currently available. The mid-infrared (MIR) prediction of milk fatty acids is relevant in this context. Five MIR methane indicators were derived from the literature and were calibrated from 600 samples analyzed by gas chromatography. Genetic parameters for these traits were estimated using single trait random regression test-day models from 619,265 records collected from 2007 to 2011 on 71,188 Holstein cows in their first three lactations. For the published indicator showing the highest relationship with the methane data (R2 = 0.88), the average daily heritability was 0.34±0.01, 0.37±0.01 and 0.34±0.01 for the first three lactations, respectively. The methane emission (g/day) was increased from beginning of lactation, reached at the highest in peak of lactation and decreased towards end of lactation. The largest differences between estimated breeding values (EBV) of sires having daughters in production eructing the highest and the lowest methane content was 21.80, 22.75 and 24.89 kg per lactation for the first three parities. Positive genetic correlations were estimated between indicator traits and milk fat and protein content. Low negative correlation was observed with milk yield. In conclusion, this study shows the feasibility to predict methane indicator traits by MIR. Moreover, the estimated genetic parameters suggest also a potential genetic variability of the quantity of methane eructed by dairy cows. [less ▲]

Detailed reference viewed: 126 (10 ULg)
Full Text
Peer Reviewed
See detailBreed-specific hematologic reference intervals in healthy adult Dogue de Bordeaux dogs
Lavoué, Rachel; Geffré, A; Braun, JP et al

in Veterinary Clinical Pathology (in press)

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailChemical composition of colostrum from Azawak cow in Niger compared with meta-analytical data
Abdou, Harouna; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Animal Genetic Resources Information = Bulletin d'Information sur les Ressources Génétiques Animales = Boletin de Informacion sobre Recursos Geneticos Animales (in press)

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h ... [more ▼]

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h from 7 Azawak cows at calving between August 27, to September 10, 2009 in the Sahel. For data from literature, twenty one (21) references were identified in the following analytical databases: PubMed, Science Direct, Google scholar, Collection from University of Liege. The references were selected according to the following two criteria: i) only studies reported on bovine colostrum were used irrespective of breeds, and ii) among the selected studies, those not providing complete information to allow meta-analytical calculation were excluded. Samples were analyzed for immunoglobulins (IgG, IgM, IgA), lactoferrin, and chemical composition (dry mater, protein, fat, lactose, ash, Ca, P, NA, K, Mg). The mean levels of IgG, IgM, dry matter, protein and fat for Azawak cows were lower (P ˂ 0.001) than those obtained in other breeds; however colostrum from the Azawak was higher in IgA but the difference was not significant. For lactose and ash, mean values for Azawak cows were higher (P ˂ 0.001) than those from the literature. Contents of Ca, P, Na and Mg in Azawak bovine colostrum were significantly higher (P ˂ 0.001) than the mean levels in form the literature data. In conclusion, the colostrum from Azawak cows appears to be lower in most immunoglobulins, in fat and in protein than the values reported in the literature, but higher in lactose and minerals. This could be an adaptation to sahelian contraints. [less ▲]

Detailed reference viewed: 37 (1 ULg)
Full Text
Peer Reviewed
See detailEfficacy of heroin-assisted treatment in Belgium: a randomised controlled trial
Demaret, Isabelle ULg; Quertemont, Etienne ULg; Litran, Géraldine et al

in European Addiction Research (in press)

Background/Aims: Heroin-assisted treatment (HAT) can improve the condition of heroin addicts still using street heroin after a methadone treatment. In Belgium, a new trial compared the efficacy of a HAT ... [more ▼]

Background/Aims: Heroin-assisted treatment (HAT) can improve the condition of heroin addicts still using street heroin after a methadone treatment. In Belgium, a new trial compared the efficacy of a HAT to existing methadone maintenance treatment. Methods: In this randomised controlled trial, HAT was limited to 12 months. Participants were assessed every 3 months. They were responders if they showed improvement on the level of street heroin use, health or criminal involvement. Results: 74 participants were randomised in the trial. The experimental group (n=36) counted 30% of responders more than the control group (n=38) at each assessment point (p<0.05), except at 12 months where the difference (11%) was no longer significant (p=0.35). Still, after 12 months, participants in the experimental group reported significantly greater improvements (p<0.05) than the control group on the level of street heroin use and on the level of physical and mental health. Both groups reported significantly less criminal facts after 12 months (p<0.001), but with no significant difference between the groups. Conclusions: This trial confirms the short-term efficacy of HAT for severe heroin addicts, who already failed methadone treatment. [less ▲]

Detailed reference viewed: 38 (10 ULg)
Full Text
Peer Reviewed
See detailCharacterizing activity sequences using Profile Hidden Markov Models
Liu, Feng; Janssens, Davy; Cui, JianXun et al

in Expert Systems with Applications (in press)

In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment ... [more ▼]

In literature, activity sequences, generated from activity-travel diaries, have been analyzed and classified into clusters based on the composition and ordering of the activities using Sequence Alignment Methods (SAM). However, using these methods, only the frequent activities in each cluster are extracted and qualitatively described; the infrequent activities and their related travel episodes are disregarded. Thus, to quantify the occurrence probabilities of all the daily activities as well as their sequential orders, we develop a novel process to build multiple alignments of the sequences and subsequently derive profile Hidden Markov Models (pHMMs). This process consists of 4 major steps. First, activity sequences are clustered based on a pre-defined scheme. The frequent activities along with their sequential orders are then identified in each cluster, and they are subsequently used as a template to guide the construction of a multiple alignment of the cluster of sequences. Finally, a pHMM is employed to convert the multiple alignment into a position-specific scoring system, representing the probability of each frequent activity at each important position of the alignment as well as the probabilities of both insertion and deletion of infrequent activities. By applying the derived pHMMs to a set of activity-travel diaries collected in Belgium as well as a group of mobile phone call location data recorded in Switzerland, the potential and effectiveness of the models in capturing the sequential features of each cluster and distinguishing them from those of other clusters, are demonstrated. The proposed method can also be utilized to improve activity-based transportation model validation and travel survey designs. Furthermore, it offers a wide application in characterizing a group of any related sequences, particularly sequences varying in length and with a high frequency of short sequences that are typically present in human behavior. [less ▲]

Detailed reference viewed: 17 (1 ULg)
Full Text
Peer Reviewed
See detailPilgrimage Certificates from the Mamluk Period: New Data
Bauden, Frédéric ULg

in Bulletin of the School of Oriental and African Studies (in press)

Detailed reference viewed: 31 (3 ULg)
Full Text
Peer Reviewed
See detailGlycine receptors control the generation of projection neurons in the developing cerebral cortex
Avila, Ariel; Vidal, P.M.; Tielens, Sylvia ULg et al

in Cell Death & Differentiation (in press)

Detailed reference viewed: 27 (3 ULg)
Full Text
Peer Reviewed
See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone haelth: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailBHS guidelines for the treatment of Burkitt lymphoma
BONNET, Christophe ULg; Janssens, A.; Wu, KL. et al

in Belgian Journal of Hematology (in press)

Burkitt lymphoma (BL) is a rare but very aggressive non-Hodgkin’s lymphoma characterized by an isolated translocation t(8;14)(q24;q32). The sporadic form is the subentity most frequently encountered in ... [more ▼]

Burkitt lymphoma (BL) is a rare but very aggressive non-Hodgkin’s lymphoma characterized by an isolated translocation t(8;14)(q24;q32). The sporadic form is the subentity most frequently encountered in our country. Diagnosis and initial work-up must be completed rapidly to start treatment as soon as possible. Positron emission tomography (PET) scan is useful for initial staging and to evaluate the chemosensitivity of the tumor during and after treatment. After debulking, it is recommended to add rituximab to chemotherapy. Currently intensive short-cycle chemotherapies (ISCC) and low intensity chemotherapies (LIC) are two valuable options. Radiotherapy is not indicated except in case of central nervous system involvement. Patients achieving complete remission must be followed carefully during the first year to detect recurrence of the disease. More than 80% of patients sustain their remission one year following initial treatment and are considered cured. For patients in partial remission or with chemosensitive relapse, autologous stem cell transplantation is recommended following re-induction with non-cross-resistant polychemotherapy. Monitoring complete blood counts and cognitive functions is important to detect late toxicity of the applied therapies. [less ▲]

Detailed reference viewed: 39 (2 ULg)
Full Text
Peer Reviewed
See detailVegetation composition and structure of some Neotropical mountain grasslands in Brazil
Le Stradic, Soizig ULg; Buisson, Elise; Fernandes, Geraldo Wilson

in Journal of Mountain Science (in press)

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailInfluence of past and future climate changes on the distribution of three Southeast Asian murine rodents
Latinne, Alice ULg; Meynard, Christine; Herbreteau, Vincent et al

in Journal of Biogeography (in press)

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailDo aphids actively search for ant partners?
Fischer, Christophe ULg; Vanderplanck, Maryse; Lognay, Georges ULg et al

in Insect Science (in press)

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is ... [more ▼]

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is largely assumed that ants actively search for their mutualistic partners namely using volatile cues; whether winged aphids (i.e. aphids’ most mobile form) are able to select ant-frequented areas had not been investigated so far. Ant-frequented sites would indeed offer several advantages for these aphids including a lower predation pressure through ant presence and enhanced chances of establishing mutuaslistic interactions with neighbour ant colonies. In the field, aphid colonies are often observed in higher densities around ant nests, which is probably linked to a better survival ensured by ants’ services. Nevertheless, this could also result from a preferential establishment of winged aphids in ant-frequented areas. We tested this last hypothesis through different ethological assays and show that the facultative myrmecophilous black bean aphid, Aphis fabae L., does not orientate its search for a host plant preferentially towards ant-frequented plants. However our results suggest that ants reduce the number of winged aphids leaving the newly colonized plant. Thus, ants involved in facultative myrmecophilous interactions with aphids appear to contribute to structure aphid populations in the field by ensuring a better establishment and survival of newly established colonies rather than by inducing a deliberate plant selection by aphid partners based on the proximity of ant colonies. [less ▲]

Detailed reference viewed: 35 (1 ULg)
Full Text
Peer Reviewed
See detailIsland floras are not necessarily more species-poor than continental ones.
Patiño, J.; Solymos, P.; Carine, M.A. et al

in Journal of Biogeography (in press)

Detailed reference viewed: 19 (1 ULg)
Full Text
Peer Reviewed
See detailDUSP3 genetic deletion confers M2-like−macrophage-dependent tolerance to septic shock
Singh, Pratibha; Dejager, Lien; Amand, Mathieu ULg et al

in Journal of Immunology (in press)

DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We report that DUSP3 is strongly expressed in human and mouse monocytes and macrophages and that its ... [more ▼]

DUSP3 is a small dual-specificity protein phosphatase with an unknown physiological function. We report that DUSP3 is strongly expressed in human and mouse monocytes and macrophages and that its deficiency in mice promotes tolerance to lipopolysaccharide (LPS)-induced endotoxin shock and to polymicrobial septic shock following cecal ligation and puncture. By using adoptive transfer experiments, we demonstrate that resistance to endotoxin is macrophage-dependent and transferable and that this protection is associated with a striking increase of M2-like macrophages in DUSP3-/- mice in both the LPS and cecal ligation and puncture models. We show that the altered response of DUSP3-/- mice to sepsis is reflected in decreased TNF production and impaired ERK1/2 activation. Our results demonstrate that DUSP3 plays a key and non-redundant role as a regulator of innate immune responses by mechanisms involving the control of ERK1/2 activation, TNF secretion and macrophage polarization. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailMonitoring Antibiotic Use and Residue in Freshwater Aquaculture for Domestic Use in Vietnam
Pham Kim, Dang; Chu, Jacqueline; Nga Thuy, Do et al

in EcoHealth (in press)

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailCommentary on recent therapeutic guidelines for osteoarthritis
Cutolo, M; Berenbaum, F; Hochberg, M et al

in Seminars in Arthritis & Rheumatism (in press)

Background Despite availability of international evidence-based guidelines for osteoarthritis (OA) management, agreement on the different treatment modalities is lacking. Method A symposium of European ... [more ▼]

Background Despite availability of international evidence-based guidelines for osteoarthritis (OA) management, agreement on the different treatment modalities is lacking. Method A symposium of European and US OA experts was held within the framework of the Annual European Congress of Rheumatology to discuss and compare guidelines and recommendations for the treatment of knee OA and to reach a consensus for management, particularly for areas in which there is no clear consensus: non-pharmacological therapy; efficacy and safety of analgesics and non-steroidal anti-inflammatory drugs (NSAIDs); intra-articular (i.a.) hyaluronates (HA); and the role of chondroitin sulfate (CS) and/or glucosamine sulfate (GS). Results All guidelines reviewed agree that knee OA is a progressive disease of the joint whose management requires non-pharmacological and pharmacological approaches. Discrepancies between guidelines are few and mostly reflect heterogeneity of expert panels involved, geographical differences in the availability of pharmacotherapies, and heterogeneity of studies included. Panels chosen for guideline development should include experts with real clinical experience in drug use and patient management. Implementation of agreed guidelines can be thwarted by drug availability and reimbursement plans, resulting in optimal OA treatment being jeopardized, HA and symptomatic slow-acting drugs for osteoarthritis (SySADOAs) being clear examples of drugs whose availability and prescription can greatly vary geographically. In addition, primary care providers, often responsible for OA management (at least in early disease), may not adhere to clinical care guidelines, particularly for non-pharmacological OA treatment. Conclusion Harmonization of the recommendations for knee OA treatment is challenging but feasible, as shown by the step-by-step therapeutic algorithm developed by European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). More easily disseminated and implemented guidance for OA treatment in the primary care setting is key to improved management of OA. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailLes voyages du goût, entre localité et exotisme.
Mescoli, Elsa ULg

in Anthropology of Food (in press)

« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au ... [more ▼]

« Savourer la nourriture et respirer la culture marocaine deviennent une expérience et une émotion unique, à découvrir et à vivre grâce à la combinaison d’arômes, goûts, couleurs, formes et musiques ». Au travers de ce slogan, un renommé restaurant d’inspiration marocaine de la ville de Milan en Italie, invitait ses clients à voyager au travers de leur sensorialité dans une culture alimentaire (et par synecdoque, une culture tout court) autre. Le goût les aurait amenés à expérimenter un exotisme, qui était néanmoins contrôlé, car certaines conditions imposées par les normes locales faisaient en sorte que le déplacement vécu ne fût pas excessivement déstabilisant. Le résultat de ces négociations consistait d’un menu qui accostait les gastronomies marocaine et italienne (ou les procédures de l’une et de l’autre) dans certains plats décrits comme « fusion », qui satisfaisaient (ou non) les exigences des clients. Dans cet article, je vise à mettre en évidence les mécanismes de production discursive et matérielle de ces plats, ainsi comme les opinions des consommateurs. Pour ce faire, j’analyserai le matériel ethnographique collecté auprès du local en question en le comparant avec les pratiques observés dans d’autres restaurants milanais. En ce qui concerne les effets obtenus, j’appuierait mon analyse sur une plateforme de médias sociaux consacrée aux recensions d’endroits et locaux touristiques. La culture alimentaire sera étudiée dans ses aspects symboliques mais aussi matériels, en faisant également recours au matériel visuel récolté. [less ▲]

Detailed reference viewed: 29 (5 ULg)
Full Text
Peer Reviewed
See detailSurvivances et métamorphoses. Les gemmes isiaques remployées au Moyen Âge et leur interprétation
Veymiers, Richard ULg

in Anabases : Traditions et Réception de l'Antiquité (in press)

Detailed reference viewed: 15 (0 ULg)
Peer Reviewed
See detailThe transition to conservation agriculture : an insularization process towards sustainability
Vankeerberghen, Audrey ULg; Stassart, Pierre M ULg; Dannevoye, Bastien ULg

in International Journal of Agricultural Sustainability (in press)

Detailed reference viewed: 31 (6 ULg)
Full Text
Peer Reviewed
See detailDefensins: « simple » antimicrobial peptides or broad-spectrum molecules ?
Suarez-Carmona, Meggy ULg; Hubert, Pascale ULg; Delvenne, Philippe ULg et al

in Cytokine & Growth Factor Reviews (in press)

Detailed reference viewed: 16 (1 ULg)
Full Text
Peer Reviewed
See detailDe Jacques Antoine aux Éperonniers : l'édition littéraire en Belgique au passé et au présent. Seconde partie : Création contemporaine et politiques du livre. Lysiane D'Haeyere aux Éperonniers
Durand, Pascal ULg; Habrand, Tanguy ULg

in Textyles : Revue des Lettres Belges de Langue Française (in press), 47

Le positionnement pionnier des Éditions Jacques Antoine dans la patrimonialisation des lettres belges, à travers la collection « Passé Présent », n’a porté ses fruits que durant une assez brève période ... [more ▼]

Le positionnement pionnier des Éditions Jacques Antoine dans la patrimonialisation des lettres belges, à travers la collection « Passé Présent », n’a porté ses fruits que durant une assez brève période, de la seconde moitié des années 1970 et au début des années 1980. Seconde partie d'un article en deux temps, celle-ci évoque les causes de la faillite du projet initial avant d'examiner les modalités de son évolution ultérieure, sous la conduite de Lysiane D’Haeyere et dans le cadre réaménagé des Éditions Les Éperonniers. L’histoire de cette continuité dans la rupture et de cette transmission de rôle éditorial est restée jusqu’à ce jour très obscure, pour des raisons qui conjoignent affaires privées et contentieux commercial. L'article éclaircit cette histoire et jette, à travers elle, un jour nouveau sur un aspect des Lettres belges de langue française où s’articulent étroitement histoire de l’édition et histoire de la littérature. Les archives confiées par les héritiers de Lysiane D’Haeyere au Centre d’Étude du Livre Contemporain de l’Université de Liège, une journée d’étude organisée le 5 mai 2010 par le CELIC avec l’appoint de témoins directs de son activité d’éditrice, ont représenté à cet égard des ressources de premier plan. [less ▲]

Detailed reference viewed: 32 (11 ULg)
Full Text
Peer Reviewed
See detailSubmarine Paleo-earthquake record of the Cinarcik segment of the North Anatolian Fault in the Marmara Sea (Turkey)
Drab, Laureen; Hubert, Aurelia ULg; Carlut, Julie et al

in Bulletin Seismological Society of America (in press)

The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk ... [more ▼]

The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk assessment for the area is constrained by the fact that the NAF system is submarine near Istanbul; thus a history of paleoearthquakes can be inferred only by using sediment cores. Here a record of turbidites was obtained in two cores and used to reconstruct the earthquake history along a main branch of the NAF, the Cinarcik Segment. Kullenberg core Klg04 (4 m long) was collected during Marmarascarps mission from a berm north of the fault and a second core (Klg03, 3.5 m long) was positioned in the Cinarcik Basin, 3 km south of the fault. Sedimentary sequences in the two cores were correlated using variations in Ca/Ti ratio, which reflect the local aquatic productivity compared with more terrigenous input. The turbidites between the two cores were then classified to distinguish the synchronous ones from the other ones. Radionuclide measurements suggest that the most recent turbidite recorded in both cores was triggered by the M=7.3 1894 earthquake. We conclude that the turbidites are earthquake-generated, based on: 1) their distinctive sedimentological and geochemical signatures, previously described and applied in the Marmara Sea; 2) the correlation of turbidites between cores at berm and basin sites; 3) the match of the most recent turbidites with a 19th century historical earthquake; and 4) the elimination of others processes. Because of its specific geomorphological location, core Klg04 likely records only mass wasting events related to the rupture on the Cinarcik Segment. To date older turbidites, we used 14C and paleomagnetic data to build an OxCal age model with a local reservoir correction (ΔR) of 400±50 yr. The Cinarcik Segment is found to have ruptured in AD1894, AD1509, sometime in the 14th century, AD989, AD740 and in the 5th century and have a mean recurrence interval of rupture between 243 and 396 years. Following the age model obtained we finally used the earthquake record history of the Cinarcik Segment to infer the rupture history of adjacent segments of the North Anatolian Fault during six earthquake cycles over the past 1500 years. [less ▲]

Detailed reference viewed: 36 (1 ULg)
Full Text
Peer Reviewed
See detailClinical pharmacology of antifungal agents to overcome drug resistance in pediatric patients
STERGIOPOULOU, Theodouli ULg; Walsh, Thomas J.

in Expert opinion on pharmacotherapy (in press), 16(2), 213-26

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological ... [more ▼]

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERED: This paper reviews the mechanisms of resistance of different classes of antifungal agents and the current understanding of pediatric antifungal pharmacology for overcoming antifungal resistance in children based on laboratory and clinical studies in the English literature. The therapeutic choices against fungal pathogens with intrinsic or acquired resistance are further reviewed. EXPERT OPINION: There is a paucity of data in the pediatric population regarding the epidemiology of the resistant organisms to different antifungal agents. It is also unknown if there are more prevalent molecular mechanisms that promote antifungal resistance. Selection and dosages of the most effective antifungal agent for overcoming the antifungal resistance is crucial. However, there are limited studies guiding the optimal dosage and duration of treatment for management of emergent antifungal resistance. Further studies are warranted to elucidate the optimal pharmacology of the current antifungal agents against resistant organisms and to advance the development of new antifungal agents. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Full Text
Peer Reviewed
See detailAn analogue of Cobham's theorem for graph directed iterated function systems
Charlier, Emilie ULg; Leroy, Julien ULg; Rigo, Michel ULg

in Advances in Mathematics (in press)

Feng and Wang showed that two homogeneous iterated function systems in $\mathbb{R}$ with multiplicatively independent contraction ratios necessarily have different attractors. In this paper, we extend ... [more ▼]

Feng and Wang showed that two homogeneous iterated function systems in $\mathbb{R}$ with multiplicatively independent contraction ratios necessarily have different attractors. In this paper, we extend this result to graph directed iterated function systems in $\mathbb{R}^n$ with contraction ratios that are of the form $\frac{1}{\beta}$, for integers $\beta$. By using a result of Boigelot {\em et al.}, this allows us to give a proof of a conjecture of Adamczewski and Bell. In doing so, we link the graph directed iterated function systems to Büchi automata. In particular, this link extends to real numbers $\beta$. We introduce a logical formalism that permits to characterize sets of $\mathbb{R}^n$ whose representations in base $\beta$ are recognized by some Büchi automata. This result depends on the algebraic properties of the base: $\beta$ being a Pisot or a Parry number. The main motivation of this work is to draw a general picture representing the different frameworks where an analogue of Cobham's theorem is known. [less ▲]

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailRugose corals across the Devonian-Carboniferous boundary in NW Turkey
Denayer, Julien ULg

in Acta Palaeontologica Polonica (in press)

Detailed reference viewed: 23 (0 ULg)
Full Text
Peer Reviewed
See detailExploratory Single Grain OSL data analysis of quartz from archeological mortars: on the use of an exponential distribution of light exposure of grains and consequences for dating
Guibert, Pierre; Urbanova, Petra; Blain, Sophie ULg et al

in Radiation Measurements (in press)

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching ... [more ▼]

Dating archaeological mortar by OSL is one of the challenging objectives leading to the chronology of ancient constructions. Single grain OSL analysis is a very convenient tool to examine the bleaching state of the series of quartz grains extracted from a mortar sample. Indeed, during the making process, sand is extracted from a sedimentary source, transported, stored then mixed with lime and set into the walls being constructed. Experience shows that incomplete bleaching is frequent for these materials. The aim of this study is to model the distribution of single grain equivalent doses of mortars following the assumption that a population of grains corresponds to a unique distribution of heterogeneously bleached grains rather than to a mixture of well bleached quartz grains with poorly bleached ones. An exponential distribution of light exposure of grains is examined. By comparing experimental distributions of doses with simulated ones, we investigate the appropriateness of this distribution function and then we calculate the average residual dose integrated into the process of the ED determination and finally the OSL age. Limits and potentials of this approach are discussed using various case-studies of structures and buildings of known age (from the roman to the post-medieval period). Even in case of very poorly bleached samples we observed that the simulated ED distribution fits satisfactorily with the experimental one, which offers new encouraging perspectives in single grain dating of mortars. [less ▲]

Detailed reference viewed: 19 (1 ULg)
Full Text
See detailImaging myeloma and related monoclonal plasma cell disorders: Still room for standard radiography?
WITHOFS, Nadia ULg; Nanni, Cristina; Fanti, Stefano et al

in Clin.Translat.Imaging (in press)

A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial ... [more ▼]

A majority of multiple myeloma patients present with osteolytic bone lesions that can cause bone pain, fractures or hypercalcaemia. Correct identification of these lesions is important in the initial assessment of the disease. Although the radiological skeletal survey is the gold standard to detect bone osteolytic lesions, it may miss small bone lesions or lesions located in the spine or pelvis due to the superimposed images of soft tissues. These limitations propelled newer imaging techniques such as positron emission tomography combined with computed tomography (PET/CT) and magnetic resonance imaging (MRI) in the diagnosis of multiple myeloma. In addition, 18F-fluorodeoxyglucose PET/CT and MRI have prognostic value and can be used to monitor disease. This review discusses the additional value of PET/CT and MRI in the management of MM. [less ▲]

Detailed reference viewed: 21 (0 ULg)
Full Text
Peer Reviewed
See detailSinging ability is rooted in vocal-motor control of pitch
Hutchins, Sean; Larrouy, Pauline ULg; Peretz, Isabelle

in Attention, Perception & Psychophysics (in press)

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and ... [more ▼]

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and vocal production, they have failed to control for the timbre of the target to be matched. In the present study, we compare pitch matching accuracy with an unfamiliar instrument (the slider) and with the voice, designed such that the slider plays back recordings of the participant’s own voice. We also measured pitch accuracy in singing a familiar melody (“Happy Birthday”) to assess the relationship between single pitch matching tasks and melodic singing. Our results showed that participants (all nonmusicians) were significantly better at matching recordings of their own voices with the slider than with their voice, indicating that vocal-motor control is an important limiting factor on singing ability. We also found significant correlations between the ability to sing a melody in tune and vocal pitch matching, but not instrumental pitch matching. Better melodic singers also tended to have higher quality voices (as measured by acoustic variables). These results provide important evidence about the ultimate causes of poor singing ability, and demonstrate that single pitch matching tasks can be useful in measuring general singing abilities. [less ▲]

Detailed reference viewed: 20 (1 ULg)
Full Text
Peer Reviewed
See detailA 24-month Study Evaluating the Efficacy and Safety of Denosumab for the Treatment of Men With Low Bone Mineral Density: Results From the ADAMO Trial.
Langdahl, Bente L.; Teglbjaerg, Christence S.; Ho, Pei-Ran et al

in The Journal of clinical endocrinology and metabolism (in press)

Context: One in 4 men in the US aged >50 will suffer an osteoporosis-related fracture. Less data are available on osteoporosis treatment in men than women. Objective: Evaluate denosumab therapy in men ... [more ▼]

Context: One in 4 men in the US aged >50 will suffer an osteoporosis-related fracture. Less data are available on osteoporosis treatment in men than women. Objective: Evaluate denosumab therapy in men with low BMD. Design: Phase 3 study with two treatment periods: a previously reported 12-month double-blind, placebo-controlled phase and a 12-month open-label phase. Setting: Multicenter in North America and Europe. Participants: 228 men entered the open-label phase and 219 completed the study. Intervention: Men from the original denosumab (long-term) and placebo (crossover) groups received denosumab 60 mg SC every 6 months. Main Outcome Measures: BMD, serum C-telopeptide (sCTX), and safety. Results: During the open-label phase, continued BMD increases occurred with long-term denosumab treatment (2.2% lumbar spine; 0.9% total hip; 1.3% femoral neck; 1.3% trochanter; and 0.2% 1/3 radius), resulting in cumulative 24-month gains from baseline of 8.0%, 3.4%, 3.4%, 4.6%, and 0.7%, respectively (all P<0.01). The crossover group showed BMD gains after 12 months of denosumab treatment similar to the long-term denosumab group during the first treatment year. Significant reductions in sCTX were observed following denosumab administration. Adverse events rates were similar between groups and no new safety signals identified. Conclusions: In men with low BMD, denosumab treatment for a second year continued to increase BMD, maintained reductions in bone resorption, and was well tolerated. BMD increased in men initiating denosumab during the second year. These effects were similar to those previously seen in postmenopausal women with osteoporosis and men with prostate cancer on androgen deprivation therapy. [less ▲]

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

Detailed reference viewed: 61 (4 ULg)
Full Text
Peer Reviewed
See detailMagie et pharmacopée : l’utilisation des végétaux dans les papyrus iatromagiques grecs
de Haro Sanchez, Magali ULg

in Mythos (in press)

The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For ... [more ▼]

The iatromagical papyri, subgenus of the magical papyri, come from Egypt. From the 1st BC to AD the 7th, they appear in the form of formularies, spells copied from them, amulets and a private letter. For many years, the study of these texts has been part of a research program of the Centre de Documentation de Papyrologie Littéraire (CeDoPaL) of the University of Liège. We will present here the results from the analysis of the content of the prescriptions with plants attested in the Greek iatromagical formularies. [less ▲]

Detailed reference viewed: 230 (8 ULg)
Full Text
Peer Reviewed
See detailHow does governmental versus private venture capital backing affect a firm's efficiency? Evidence from Belgium
Alperovych; Hübner, Georges ULg; Lobet, Fabrice

in Journal of Business Venturing (in press)

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We ... [more ▼]

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We find that the government VC-backed firms display significant reductions in productivity. No significant differences in efficiency are found in firms backed by private VC compared with their non-VC-backed peers. Finally, significant reductions in efficiency exist in targets of government VC compared to their non-VC-backed peers. [less ▲]

Detailed reference viewed: 21 (6 ULg)
Full Text
Peer Reviewed
See detailBayesian versus frequentist methods for estimating disease true prevalence and 4 diagnostic test performance
Sanogo, M; Abatih, E; Saegerman, Claude ULg

in Veterinary Journal (in press)

Detailed reference viewed: 24 (2 ULg)