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See detailMonitoring of osteoporosis therapy
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Best Practice & Research. Clinical Endocrinology & Metabolism (in press)

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance ... [more ▼]

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance with these treatments is not optimal, and a number of patients could be considered as non-responders. Consequently, monitoring anti-osteoporotic therapy could be part of successful osteoporosis management. Currently, no formal well-accepted clinical practice guidelines are available for monitoring anti-osteoporosis therapies. Changes in bone mineral density and bone turnover markers, while on therapy, have potential value in monitoring treatment but their assessment and, consequently, their benefits could be limited by metrological and clinical issues. Moreover, their effectiveness is probably drug dependant. Recommendation for the standardisation of the methodology when analysing the potential relevance of tools for the monitoring of osteoporosis therapy is needed. [less ▲]

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See detailContribution à un lexique épigraphique: "deltographéma"
Famerie, Etienne ULg

in Zeitschrift für Papyrologie und Epigraphik (in press)

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See detailGammapathie monoclonale de signification indéterminée : information destinée aux médecins référents
CAERS, Jo ULg; Binsfeld, Marilène ULg; Muller, Joséphine ULg et al

in Revue Médicale de Liège (in press)

Les gammapathies monoclonales de signification indéterminée (GMSI) sont fréquentes dans la population générale. Leur potentiel évolutif malin impose une surveillance clinique régulière et prolongée ... [more ▼]

Les gammapathies monoclonales de signification indéterminée (GMSI) sont fréquentes dans la population générale. Leur potentiel évolutif malin impose une surveillance clinique régulière et prolongée. Cependant, les GMSI forment un groupe très hétérogène et tous les patients n’ont pas le même risque de transformation maligne. Plusieurs critères biologiques simples, disponibles en routine ont été identifiés comme facteurs prédictifs de la transformation. Les scores prédictifs de transformation maligne combinant plusieurs de ces facteurs permettront probablement la classification des patients en fonction de leur risque évolutif. La prise en charge pourra ainsi être adaptée au risque individuel de chaque patient [less ▲]

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See detailPIXE identification of the provenance of ferruginous rocks used by Neanderthals
Mathis, François ULg; Bodu, Pierre; Dubreuil, Olivier ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (in press)

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a ... [more ▼]

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a rich industry based on the discoid mode, associated with numerous fragments of red and yellow iron oxide-rich rocks showing clear traces of powder production (abrasion, striation, scraping), which are exceptional remains for this remote period. Archeological material and geological samples from the close environment were studied by PIXE and by petrographical observations made on thin sections. The geological sources were identified by means of PIXE analyses on two IBA facilities: AGLAE (2 MV tandem) at the C2RMF in Paris and the cyclotron of the IPNAS (University of Liège). We paid particular attention to the comparison of results obtained on both installations by using the same set of geological standards and by a fine evaluation of the limit of detection relative to each trace elements of interest for both experimental set ups. The elemental fingerprint of one geological source of iron-rich concretions corresponds clearly with the archaeological collection. At least, this investigation demonstrates that the colouring materials were minutely selected in the close neighbouring of the site by the Neanderthals. [less ▲]

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See detailSome misunderstood or unknown tricks (XIII) (LaTeX)
Merciadri, Luca ULg

in TUGboat (in press)

We will here again consider many tips and tricks. This time, they will mostly come from Glad Deschrijver, TeX Tricks, 2011. (http://users.ugent.be/~gdschrij/LaTeX/textricks.html.) Tricks: vertically ... [more ▼]

We will here again consider many tips and tricks. This time, they will mostly come from Glad Deschrijver, TeX Tricks, 2011. (http://users.ugent.be/~gdschrij/LaTeX/textricks.html.) Tricks: vertically aligned itemize environments, allowing linebreaks after comma in math mode, writing under and over elements, and using stacks, footnotes with a new number at each section, footnotes in tabular, splitting algorithm environments on multiple pages, let " produce opening/closing quotation marks, indenting some text but not the first line, using diagonal dots positioned according to the opposite diagonal, using a centered verbatim environment, drawing a table with dashed lines, shaded cells and arrows pointing at a row and a column, correct spacing around square brackets (used for sets) in math mode. [less ▲]

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See detailAtomistic account of structural and dynamical changes induced by small binders in the double helix of a short DNA
Fresch, Barbara ULg; Remacle, Françoise ULg

in Physical Chemistry Chemical Physics [=PCCP] (in press)

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See detailSur Capitalisme, désir et servitude. Lettre à Frédéric Lordon
Pieron, Julien ULg

in Dissensus (in press), 6(printemps 2014),

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See detailAIR VERSUS GROUND TRANSPORT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: EXPERIENCE IN A RURAL-BASED HELICOPTER MEDICAL SERVICE
MOENS, Didier ULg; Stipulante, Samuel ULg; Donneau, Anne-Françoise ULg et al

in European Journal of Emergency Medicine (in press)

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We ... [more ▼]

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We designed a prospective study involving patients with acute myocardial infarction aimed at the evaluation of the potential benefit of such primary HEMS interventions as compared with classical EMS ground transport. Methods & results This prospective study was conducted from July 1, 2007 to June 15, 2012. Successive patients with ST-segment elevation myocardial infarction (STEMI) eligible for percutaneous coronary intervention (PCI) were included. Simulated ground-based access times were computed using a digital cartographic program, allowing the estimation of healthcare system delay from call to admission to the catheterisation laboratory. During the study period, 4485 patients benefited from HEMS activations. Of these patients, 342 (8%) suffering from STEMI were transferred for primary PCI. Median primary response time time was 11 min (IQR: 8 - 14 min) using the helicopter and 32 min (25 – 44 min) using road transport. Median transport time using HEMS was 12 min (9 – 15 min) and 50 min (36 – 56 min) by road. The median system delay using HEMS was 52 min (45 – 60 min), while this time was 110 min (95 – 126 min) by road. Finally, the system delay median gain was 60 min (47 – 72 min). Conclusions Using HEMS in a rural region allows STEMI patients to benefit from appropriate rescue care with similar delays as those seen in urban patients. [less ▲]

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See detailSome misunderstood or unknown tricks (XI) (LaTeX) and encoding issues (II)
Merciadri, Luca ULg

in TUGboat (in press)

Three subjects will be detailed: 1. Using LaTeX syntax as an unambiguous way to communicate, 2. Writing a bold \ell, 3. Fonts' encodings.

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See detailCircadian and circannual variations in cord blood hematopoietic cell composition
Servais, Sophie ULg; BAUDOUX, Etienne ULg; Brichard, B. et al

in Haematologica (in press)

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See detailArsinoe II come dea attraverso le sue epiclesi cultuali
Caneva, Stefano ULg

in Athenaeum : Studii Periodici di Letteratura e Storia (in press)

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con ... [more ▼]

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con l’eccezione dell’epiclesi esclusiva Philadelphos. Scopo della ricerca è 1) una valutazione delle strategie di inserimento della nuova dea nel pantheon tradizionale; 2) una riflessione sull’autoconsapevolezza degli antichi in relazione alla propria tradizione religiosa, per come essa si manifesta attraverso l’oculata manipolazione di un elemento essenziale nella definizione della divinità, qual è il nome divino. Un’Appendice elenca, in tre tabelle, tutte le denominazioni greche di Arsinoe II (esclusa Philadelphos), fornendo indicazioni sulla fonte, la sua collocazione spaziale e temporale e sulla divinità tradizionale di riferimento. [less ▲]

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See detailThe role of olfaction in wireworms: a review on foraging behavior and sensory apparatus
Barsics, Fanny ULg; Haubruge, Eric ULg; Francis, Frédéric ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Introduction Integrated management of wireworms (Coleoptera: Elateridae) depends upon approaches applied both above- and belowground, and over several spatial scales. While foraging, these soil pests use ... [more ▼]

Introduction Integrated management of wireworms (Coleoptera: Elateridae) depends upon approaches applied both above- and belowground, and over several spatial scales. While foraging, these soil pests use biotic and abiotic signals to orientate towards target plant organs. Development of efficient techniques for implementation in integrated strategies relies upon improved knowledge of this process. In particular, an important step consists of elucidating the role of volatile organic compounds (VOC), emitted by belowground plant organs, in wireworm chemical ecology. This would have a positive impact on push-pull strategies and varietal selection developed against these insects. Literature In this work, we summarized the available data regarding wireworm foraging behavior as well as variables that should be considered when studying the potential role of plant-produced volatile semiochemicals. This includes CO2 gradients and other host-related cues, temperature, relative humidity and soil moisture, and wireworm physiological stage. We also review what is known of the sensory apparatus of wireworms, since this is involved in every step of the foraging process. Conclusion Some baseline data for studying VOC related wireworm foraging behavior exists. Using it as a tool in applied entomology should result in discovery of the semiochemicals that underpin trophic interactions involving these pests. However, most of the key pest species are not fully described with regards to the parameters detailed here. Obtaining accurate information to fill the current knowledge gaps will be needed in order to devise new integrated management strategies. [less ▲]

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See detailSpore assemblages from Upper Ordovician and Lowermost Silurian sediments recovered from the Qusaiba-1 shallow core hole, Qasim region, central Saudi Arabia
Wellman, Charles H.; Steemans, Philippe ULg; Miller, M.A.

in Review of Palaeobotany and Palynology (in press), ?

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See detailBayesian versus frequentist methods for estimating disease true prevalence and 4 diagnostic test performance
Sanogo, M; Abatih, E; Saegerman, Claude ULg

in Veterinary Journal (in press)

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See detailVehicle routing problems with loading constraints: State-of-the-art and future directions
Pollaris, Hanne; Braekers, Kris; Caris, An et al

in OR Spectrum (in press)

Distributors are faced with loading constraints in their route planning. These loading constraints include multi-dimensional packing constraints, unloading sequence constraints, stability constraints and ... [more ▼]

Distributors are faced with loading constraints in their route planning. These loading constraints include multi-dimensional packing constraints, unloading sequence constraints, stability constraints and axle weight limits. Not taking into account these loading constraints would make the planning often not feasible in practice and gives rise to last-minute changes in planning which may result in additional costs. The development of vehicle routing models that incorporate loading constraints is vital for a more efficient planning of routes. The number of contributions to this field of research has increased enormously in the last couple of years. Almost sixty percent of the papers that study the integration of loading constraints in routing models are published after 2009. The contribution of this paper is twofold. First, an overview of recent developments in this research field is provided. Literature on all transport modes in which loading constraints play a key role is discussed (trucks, airplanes, ships, and automated guided vehicles). To identify the loading constraints considered in each paper, a state-of-the-art classification scheme on loading problems is used. Second, research gaps and opportunities for future research are identified. [less ▲]

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See detailDo aphids actively search for ant partners?
Fischer, Christophe ULg; Vanderplanck, Maryse; Lognay, Georges ULg et al

in Insect Science (in press)

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is ... [more ▼]

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is largely assumed that ants actively search for their mutualistic partners namely using volatile cues; whether winged aphids (i.e. aphids’ most mobile form) are able to select ant-frequented areas had not been investigated so far. Ant-frequented sites would indeed offer several advantages for these aphids including a lower predation pressure through ant presence and enhanced chances of establishing mutuaslistic interactions with neighbour ant colonies. In the field, aphid colonies are often observed in higher densities around ant nests, which is probably linked to a better survival ensured by ants’ services. Nevertheless, this could also result from a preferential establishment of winged aphids in ant-frequented areas. We tested this last hypothesis through different ethological assays and show that the facultative myrmecophilous black bean aphid, Aphis fabae L., does not orientate its search for a host plant preferentially towards ant-frequented plants. However our results suggest that ants reduce the number of winged aphids leaving the newly colonized plant. Thus, ants involved in facultative myrmecophilous interactions with aphids appear to contribute to structure aphid populations in the field by ensuring a better establishment and survival of newly established colonies rather than by inducing a deliberate plant selection by aphid partners based on the proximity of ant colonies. [less ▲]

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See detailSiting Controversies Analysis: Framework and Method for Questioning the Procedure
Rossignol, Nicolas ULg; Parotte, Céline ULg; Joris, Geoffrey ULg et al

in Journal of Risk Research (in press)

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the ... [more ▼]

Siting controversies are commonplace, as well against the construction of roads, railways, nuclear waste disposals, as against windfarms. Local citizens resist against siting decisions taken by the authorities, following a dynamics often quoted as ‘Not In My Back Yard’. Yet contested for its lack of analytical value, NIMBY is still used strategically by actors to qualify citizens as irrational and egoistic. Beyond this labelling, many factors are investigated to understand the dynamics behind siting controversies. In this paper, we focus on the impact of the legal procedure structuring the implantation of windfarms in the Walloon Region (Belgium), and its translations within different decision making processes in specific case studies. To that regard, we consider the legal procedure as a ‘public policy instrument’. It is neither neutral nor natural, and carry values and interests. It organizes inter-personal relations between actors, and is potentially catalyzer of frustrations. In addition, this legal procedure is the object of translations within different contexts, including different actors participating to specific decision making processes. The empirical approach of this paper is based on case studies data and on the use of an innovative methodology called ‘Open Process Workshop’. This methodology consists in a structured workshop with key stakeholders, during which the legal procedure is questioned. Overall, we demonstrate that the focus on the legal procedure - and its translations within different decision making processes - allows systemic analysis providing deep understandings of controversies and reaffirming the interlinks between ‘the social’ and ‘the technical’ in such controversies. In addition, we argue that the methodology used fosters the production of innovative knowledge, mutual understanding and collective learning between the participants. [less ▲]

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See detailA review of inversion techniques related to the use of relationship matrices in animal breeding
Faux, Pierre ULg; Gengler, Nicolas ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

In animal breeding, prediction of genetic effects is usually obtained through the use of mixed models. For any of these genetic effects, mixed models require the inversion of the covariance matrix ... [more ▼]

In animal breeding, prediction of genetic effects is usually obtained through the use of mixed models. For any of these genetic effects, mixed models require the inversion of the covariance matrix associated to that effect, which is equal to the associated relationship matrix times the associated component of the genetic variance. Given the size of many genetic evaluation systems, computing the inverses of these relationship matrices is not trivial. In this review, we aim to cover computational techniques that ease inversion of relationship matrices used in animal breeding for prediction of the following different types of genetic effects: additive effect, gametic effect, effect due to presence of marked quantitative trait loci, dominance effect and different epistasis effects. Construction rules and inversion algorithms are detailed for each relationship matrix. In the final discussion, we draw up a common theoretical frame to most of the reviewed techniques. Two computational constraints come out of this theoretical frame: setting up the matrix of dependencies between levels of the effect and setting up some parts (diagonal or block-diagonal elements) of the relationship matrix to be inverted. [less ▲]

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See detailA.P.M.H. Lardinois, J.H Blok et M.G.M. Van der Poel, Sacred Words: Orality, Literacy and Religion, Leiden-Boston, Brill, 2011
Delli Pizzi, Aurian ULg

in Antiquité Classique : Revue Interuniversitaire d'Etudes Classiques (in press)

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See detailIsotopic tracing of sediment components that are assimilated by epibiontic juveniles of Holothuria scabra (Holothuroidea)
Plotieau, Thomas; Lepoint, Gilles ULg; Lavitra, Thiery et al

in Journal of the Marine Biological Association of the United Kingdom (in press)

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic ... [more ▼]

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic fraction it assimilates in practice. In this study we report experimental results where H. scabra’s diet was supplemented with various 15N-labelled organic fractions of sediment. We used juveniles weighing between 38- 88 mg at the beginning of the experiment (ca. 2 cm long and 30 days old). Their growth was measured over a four week period and their 15N composition recorded. The results showed that H. scabra juveniles assimilated all added organic components from both dissolved and particulate fractions of the sediment. Bacteria seem to be an important food source for juveniles, even more so than microphytobenthos (diatoms). [less ▲]

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See detailDifferences in species–area relationships among the major lineages of land plants: a macroecological perspective
Patino Llorente, Jairo ULg; Weigelt, P.; Guilhaumon, F. et al

in Global Ecology & Biogeography (in press)

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See detailThe open-air site of Tolbor 16 (Northern Mongolia): preliminary results and perspectives
Zwyns, N.; Gladyshev; Gunchinsuren, B. et al

in Quaternary International (in press)

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See detailLe rire du groupe
Saint-Amand, Denis ULg

in Žurnals Letonica (in press)

La période fin de siècle s’accompagne, dans le champ littéraire français, du développement d’une série de groupuscules plus ou moins organisés et volontiers potaches. Au cœur de ces associations liées de ... [more ▼]

La période fin de siècle s’accompagne, dans le champ littéraire français, du développement d’une série de groupuscules plus ou moins organisés et volontiers potaches. Au cœur de ces associations liées de près ou de loin à ce qu’Ernest Raynaud qualifiera de « mêlée symboliste » (1920-1922), le rire fonctionne comme un véritable ciment social, renforçant les liens des membres de la collectivité et redoublant l’exclusion de ceux qui n’en sont pas. Héritiers d’entreprises collectives comme Le Parnassiculet contemporain (1866) et l’Album zutique (composé en 1871 et tenu délibérément à l’écart des circuits de diffusion du livre), les agents engageant les projets des Hydropathes, des Hirsutes, des Jemenfoutistes ou de l’incontournable cabaret du Chat Noir se rassemblent non seulement dans une perspective dérisoire, mais encore se dotent-ils d’un discours qui, plus qu’un simple divertissement, présente cette dérision comme principe régulant l’activité collective. Ce sont, à l’aune des cas susmentionnés, quelques-uns de ces discours du rire collectif fin de siècle que nous explorons ici, en nous penchant sur les mécanismes rhétoriques qui les fondent et sur les grandes logiques (d’opposition à des figures spécifiques ou à des institutions) qui les motivent, en cherchant à mettre en lumière la façon dont cette omniprésence de la dérision est directement provoquée par l’état du champ littéraire de l’époque. [less ▲]

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See detailA reassessment of the use of Posidonia oceanica and Mytilus galloprovincialis to biomonitor the coastal pollution of trace elements: New tools and tips
Richir, Jonathan ULg; Gobert, Sylvie ULg

in Marine Pollution Bulletin (in press)

The present study gives a summary using state-of-the-art technology to monitor Posidonia oceanica and Mytilus galloprovincialis as bioindicators of the pollution of the Mediterranean littoral with trace ... [more ▼]

The present study gives a summary using state-of-the-art technology to monitor Posidonia oceanica and Mytilus galloprovincialis as bioindicators of the pollution of the Mediterranean littoral with trace elements (TEs), and discusses their complementarity and specificities in terms of TE bioaccumulation. Furthermore, this study presents two complementary indices, the Trace Element Spatial Variation Index (TESVI) and the Trace Element Pollution Index (TEPI): these indices were shown to be relevant monitoring tools since they led to the ordering of TEs according to the overall spatial variability of their environmental levels (TESVI) and to the relevant comparison of the global TE pollution between monitored sites (TEPI). In addition, this study also discusses some underestimated aspects of P. oceanica and M. galloprovincialis bioaccumulation behaviour, with regard to their life style and ecophysiology. It finally points out the necessity of developing consensual protocols between monitoring surveys in order to publish reliable and comparable results. [less ▲]

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See detailMartin Heidegger, Extrait du dernier cours de Marbourg
Pieron, Julien ULg

in Philosophie (in press)

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See detailEffect of bovine colostrum intake on growth, reproductive parameters and survival in red kids
Harouna, Abdou; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Journal of Animal Physiology & Animal Nutrition (in press)

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition ... [more ▼]

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition, fertility, fecundity, prolificacy) and mortality rate among red kids. The study was conducted at the goat farm secondary centre of Maradi in Niger from September 2010 to September 2011. The control animals (n = 20) were left with their mother, while the treatment animals (n = 20) received in addition 50 ml/animal/day of bovine colostrum at birth and 15 ml/animal/day from d2 to d15. Weight was measured weekly from birth to d365. Mortalities were also recorded over the same period. For reproductive parameters, observations began at weaning (d197). Growth rate was higher (p < 0.001) in supplemented animal, and the treatment effects on ADG were observed up to 150 day after the end of supplementation. A similar long-lasting trend was also observed in relation to the mortality rate (25% for ColG vs. 55% for ConG; p = 0.05). The age at first kidding tended to be lower in the treated group (13.8 0.7 vs. 14.1 0.8 month; p < 0.1). In conclusion, mild bovine colostrum supplementation induces a long-lasting positive impact on growth rate and to a lower extent on reproduction parameters and survival rate. [less ▲]

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See detailLa première interprétation heideggérienne de la Monadologie
Pieron, Julien ULg

in Philosophie (in press)

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See detailÉtude des contraintes mécaniques locomotrices chez le cheval
Noble, Prisca ULg; Collin, Bernard ULg; Denoix, Jean-Marie et al

in Annales de Médecine Vétérinaire (in press)

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some ... [more ▼]

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some equine diseased locomotor systems. In order to understand better the contraints in the equine locomotor dynamics, some investigations have been carried out. Moreover, some measurement methods, based on the mechanics of Newton, have been performed. This review shows the different measurement techniques and introduces the mechanical basis that are compulsory for the understanding of the equine locomotor apparatus functioning. [less ▲]

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See detail“How are you Vulnerable?”: Using Participation for Vulnerability Analysis in Emergency Planning
Rossignol, Nicolas ULg; Turcanu, Catrinel; Fallon, Catherine ULg et al

in Journal of Risk Research (in press)

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science ... [more ▼]

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science and Technology Studies (STS) Vulnerability Approach seems very promising. Relying on a constructivist paradigm, it is based on an inductive collection and analysis of a wide range of factors, with a particular focus on cultural factors and actual day-to-day practices. In this paper, we present the roots of this approach and we display findings based on three case studies exploring emergency planning in three different contexts (a city near a SEVESO plant, a school near a nuclear plant, and a city confronted to multiple catastrophic scenarios). The cases studies were realized by conducting three Focus Groups with different types of stakeholders (citizens, teachers, firemen, decision makers, etc.). After presenting the results of the case studies, we discuss how stakeholders’ participation can inform such type of vulnerability analysis in the context of emergency planning. We argue that participation fosters a deep understanding of actual safety governance practices which allows innovative results to emerge as well as it initiates a learning process among the participants. It contributes to questioning the relations between decision-makers, experts and citizens. It has the potential of bypassing the positivist and quantitative rationale of safety, and thus, of redefining the vulnerability governance. As a conclusion, we question the role of such STS vulnerability approach within the actual vulnerability governance. [less ▲]

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See detailChemical composition of colostrum from Azawak cow in Niger compared with meta-analytical data
Abdou, Harouna; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Animal Genetic Resources Information = Bulletin d'Information sur les Ressources Génétiques Animales = Boletin de Informacion sobre Recursos Geneticos Animales (in press)

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h ... [more ▼]

This study aimed at comparing data obtained from Azawak zebu colostrum with literature data. The comparison was performed by a meta-analytical approach. Colostrum samples were hand-collected after 5 h from 7 Azawak cows at calving between August 27, to September 10, 2009 in the Sahel. For data from literature, twenty one (21) references were identified in the following analytical databases: PubMed, Science Direct, Google scholar, Collection from University of Liege. The references were selected according to the following two criteria: i) only studies reported on bovine colostrum were used irrespective of breeds, and ii) among the selected studies, those not providing complete information to allow meta-analytical calculation were excluded. Samples were analyzed for immunoglobulins (IgG, IgM, IgA), lactoferrin, and chemical composition (dry mater, protein, fat, lactose, ash, Ca, P, NA, K, Mg). The mean levels of IgG, IgM, dry matter, protein and fat for Azawak cows were lower (P ˂ 0.001) than those obtained in other breeds; however colostrum from the Azawak was higher in IgA but the difference was not significant. For lactose and ash, mean values for Azawak cows were higher (P ˂ 0.001) than those from the literature. Contents of Ca, P, Na and Mg in Azawak bovine colostrum were significantly higher (P ˂ 0.001) than the mean levels in form the literature data. In conclusion, the colostrum from Azawak cows appears to be lower in most immunoglobulins, in fat and in protein than the values reported in the literature, but higher in lactose and minerals. This could be an adaptation to sahelian contraints. [less ▲]

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See detailScience et Dynastie en Belgique : les "conseillers scientifiques" du Roi sous Albert Ier et Léopold III
Pirot, Pascal ULg

in Mosaïque, revue de jeunes chercheurs en SHS – Lille Nord de France – Belgique (in press)

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See detailFermentation profile of Saccharomyces cerevisiae and Candida tropicalis as starter cultures on barley malt medium
Alloue-Boraud, Mireille; N’Guessan, Kouadio; Djeni, Théodore et al

in Journal of Food Science & Technology (in press)

Saccharomyces cerevisiae C8-5 and Candida tropicalis F0-5 isolated from traditional sorghum beer were tested for kinetic parameters on barley malt extract, YPD (863 medium) and for alcohol production. The ... [more ▼]

Saccharomyces cerevisiae C8-5 and Candida tropicalis F0-5 isolated from traditional sorghum beer were tested for kinetic parameters on barley malt extract, YPD (863 medium) and for alcohol production. The results showed that C. tropicalis has the highest maximum growth rate and the lowest doubling time. Values were 0.22 h-1 and 0.32 h-1 for maximum growth rate, 3 h 09 min and 2 h 09 min for doubling time respectively on barley malt extract and YPD. On contrary, glucose consumption was the fastest with S. cerevisiae (-0.36 g/l/h and -0.722 g/l/h respectively on barley malt extract and YPD). When these two yeasts were used as starters in pure culture and co-culture at proportion of 1:1 and 2:1 (cell/cell) for barley malt extract fermentation, we noticed that maltose content increased first from 12.12 g/l to 13.62-16.46 g/l and then decreased. The highest increase was obtained with starter C. tropicalis + S. cerevisiae 2:1. On contrary, glucose content decreased throughout all the fermentation process. For all the starters used, the major part of the ethanol was produced at 16 h of fermentation. Values obtained in the final beers were 11.4, 11.6, 10.4 and 10.9 g/l for fermentation conducted with S. cerevisiae, C. tropicalis, C. tropicalis + S. cerevisiae 1:1 and C. tropicalis + S. cerevisiae 2:1. Cell viability measurement during the fermentation by using flow cytometry revealed that the lowest mean channel fluorescence for FL3 (yeast rate of death) was obtained with C. tropicalis + S. cerevisiae 2:1 after 48 h of fermentation. [less ▲]

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See detailLa maladie de Lyme entre cadrage infectieux, vectoriel et zoonotique : vers une écologisation des problèmes sanitaires
Massart, Clémence

in VertigO : la Revue Electronique en Sciences de l'Environnement (in press)

This paper is devoted to the qualification of Lyme disease in France. Firt vectorial disease in the northern hemisphere, Lyme diseas is transmitted by a genus of tick called Ixodes (in Europe by Ixodes ... [more ▼]

This paper is devoted to the qualification of Lyme disease in France. Firt vectorial disease in the northern hemisphere, Lyme diseas is transmitted by a genus of tick called Ixodes (in Europe by Ixodes ricinus ; in Asia by Ixodes persulcatus ; in United States and in Canada by Ixodes scapularis). Concerned only with human health and limited to Lyme, a first framing has grown around physicians and patients which are involved in a controversy. Progressively, a second framing has emerged, called vectorial and structured around ecologists, normally not involved in human health. Based on the vector, this framing includes other diseases transmitted by Ixodes ricinus which, during the last 30 years, have been discovered : Tick-Borne Encephalitis, Babesia divergens, Bartonella infection, Tularemia, etc. Linked to these new pathologies, the media coverage of Lyme has finally opened the « vectorial transmission category » – usually associated to mosquitoes and south countries – to ticks and diseases from the north. A third framing dedicated to animal reservoir and called zoonotic is emerging at last. We can see in that framing overlapping a kind of “ecologization” of sanitary issues. [less ▲]

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See detailA note on weighted likelihood and Jeffreys modal estimation of proficiency levels in polytomous item response models
Magis, David ULg

in Psychometrika (in press)

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this ... [more ▼]

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this note is to extend this result to polytomous item response models. First, a general condition is derived to ensure the perfect equivalence between these two estimators. Second, it is shown that this condition is fulfilled by two broad classes of polytomous models including, among others, the partial credit, rating scale, graded response and nominal response models. [less ▲]

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See detailStakeholder incentives and aid effectiveness: A case study in the health district of Kayes in Mali
Devahive, Eva; Paul, Elisabeth ULg; Samaké, Salif et al

in Journal of Development Studies (in press)

This case study analyses how far donors implement aid effectiveness principles at health district level in Mali, and why. It shows that not all aid effectiveness principles are implemented at a similar ... [more ▼]

This case study analyses how far donors implement aid effectiveness principles at health district level in Mali, and why. It shows that not all aid effectiveness principles are implemented at a similar degree. Most projects have limited impact on health services, but many programmes supported by donors offer positive opportunities for health system strengthening. The representations of different categories of stakeholders diverge – notably, regarding the role of different actors in service provision. A number of consistent strategic logics influence actors’ behaviour. We show that while many donors have committed at global level to respect aid effectiveness principles, implementation lags behind. [less ▲]

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See detailBreed-specific hematologic reference intervals in healthy adult Dogue de Bordeaux dogs
Lavoué, Rachel; Geffré, A; Braun, JP et al

in Veterinary Clinical Pathology (in press)

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See detailClimate-controlled palynofacies and miospore biostratigraphy of the Early Devonian Jauf Formation, northern Saudi Arabia
Breuer, Pierre; Leszczynski, S.; Miller, M.A. et al

in Review of Palaeobotany and Palynology (in press)

The Jauf Formation miospore succession is synthesized in terms of paleoenvironments and sequence stratigraphy. The data set for this study is obtained from four overlapping, continuously cored, and ... [more ▼]

The Jauf Formation miospore succession is synthesized in terms of paleoenvironments and sequence stratigraphy. The data set for this study is obtained from four overlapping, continuously cored, and extensively sampled, boreholes that for a 940 ft composite section. The Jauf Formation ranges in age from late Pragian to latest Emsian. The palynological assemblages, recognized herein, provide the basis for recognizing depositional environments present in the Early Devonian of northern Saudi Arabia. Transgressive – regressive cycles are indicated, not only by lithology but by marked changes in the marine to terrestrially dominated palynological assemblages. Flooding events are recognized by the replacement of spore dominated assemblages by organic-walled microphytoplankton. The maximum flooding interval for the Jauf is reinterpreted based on a correlative event consisting of diverse acritarchs and abundant chitinozoans. [Add details on the paly and sequence stratigraphy here. No.cycles and order.] The new northern Gondwanan biozonation developed by Breuer and Steemans (2012) and used here allows a high-resolution regional biozonation for the Arabian Plate and more intercontinental [?] correlation of the Jauf Formation with other Gondwanan and Euramerican localities. One new spore genus (Zonohilates) and four spore species (Insculptospora maxima, Camarozonotriletes alruwailii, Devonomonoletes crassus and Zonohilates vulneratus) are newly proposed. [less ▲]

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See detailSome misunderstood or unknown LaTeX tricks (XIV) and LaTeX learning curve
Merciadri, Luca ULg

in TUGboat (in press)

We will here give three tricks: i. using a personalized \overline, ii. boxing every digit of an integer, iii. using \scalebox. I will then expose my point of view about the LaTeX learning curve, and give ... [more ▼]

We will here give three tricks: i. using a personalized \overline, ii. boxing every digit of an integer, iii. using \scalebox. I will then expose my point of view about the LaTeX learning curve, and give some of the most common beginners’ mistakes. [less ▲]

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See detailA New Shift-Share Method
Artige, Lionel ULg; Van Neuss, Leif ULg

in Growth and Change (in press)

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant ... [more ▼]

Shift-share analysis is a decomposition technique widely used in regional studies to quantify an industry-mix effect and a competitive effect on the growth of regional employment (or any other relevant variable) relative to the national average. This technique has always been subject to criticism for its lack of theoretical basis. This paper presents a critical assessment of the methods suggested by Dunn (1960) and by Esteban-Marquillas (1972) and proposes a new shift-share method, which separates out the two effects unambiguously. By way of illustration, we provide an application to manufacturing employment in the Belgian provinces between 1995 and 2007. [less ▲]

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See detailFirst ‘in situ’ determination of gas transport coefficients (DO2, DAr and DN2 ) from bulk gas 2 concentration measurements (O2, N2, Ar) in natural sea ice
Crabeck, O.; Delille, Bruno ULg; Rysgaard, S. et al

in Marine Chemistry (in press)

We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5 ... [more ▼]

We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5% O2, 71.4% N2 and 1.09% Ar. Most previous studies suggest that convective transport is the main driver of gas displacement in sea ice and have neglected diffusion processes. According to our data, brines were stratified within the ice, so that no convective transport could occur within the brine system. Therefore, diffusive transport was the main driver of gas migration. By analysing the temporal evolution of an internal gas peak within the ice, we deduced the bulk gas transport coefficients for oxygen (DO2), argon (DAr) and nitrogen (DN222 ). The values fit to the few existing estimates from experimental work, and are close to the diffusivity values in water (10-5 cm2 s-124 ). We suggest that gas bubbles escaping from the brine to the atmosphere - as the ice gets more permeable during melt could be responsible for the previously reported high transport coefficients. These results underline that when there is no convective transport within the sea ice, the transport of gas by diffusion through the brines, either in the liquid or gaseous phases, is a major factor in controlling the ocean–atmosphere exchange. [less ▲]

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See detailLa maladie de Lyme entre cadrage infectieux, vectoriel et zoonotique : vers une écologisation des problèmes sanitaires ?
Massart, Clémence ULg

in VertigO : la Revue Electronique en Sciences de l'Environnement (in press)

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ... [more ▼]

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ricinus en Europe ; Ixodes persulcatus en Asie ; Ixodes scapularis aux États-Unis et au Canada). Les médecins et les malades ont d’abord développé un cadrage infectieux, ancré dans la santé humaine, réservé à Lyme et soumis à une vive controverse. Progressivement, un second cadrage vectoriel s’est structuré autour des entomologistes médicaux puis des écologues, généralement étrangers à la problématique des maladies humaines. Axé sur le vecteur, ce cadrage englobe les autres maladies transmises par Ixodes ricinus en Europe qui, durant les 30 dernières années, n’ont cessé d’être découvertes : bartonnelles, babésioses, tularémie, encéphalite à tiques, etc. Combinée à ces nouvelles pathologies, la notoriété de Lyme a finalement contribué à ouvrir la catégorie « transmission vectorielle » – traditionnellement associée aux moustiques des pays tropicaux – aux tiques et aux maladies de l’hémisphère nord qu’elles véhiculent. Un troisième cadrage axé sur les réservoirs et qualifié de zoonotique commence enfin à se dessiner. Il faut reconnaître dans cette juxtaposition des cadrages – infectieux, vectoriel et zoonotique – une forme d’écologisation des problèmes sanitaires. [less ▲]

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See detailPérils de la copie : les cas de l’Estoire del Saint Graal, du Merlin et de la Suite Vulgate
Combes, Annie ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailChemical modifications of the N-methyl laudanosine scaffold point to new directions for SK channels exploration
Badarau, Eduard; Dilly, Sébastien ULg; Wouters, Johan et al

in Bioorganic & Medicinal Chemistry Letters (in press)

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See detailChild labour, Agency and Family dynamics: The Case of Mining in Katanga (DRC)
Andre, Géraldine ULg; Godin, Marie

in Childhood (in press)

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into ... [more ▼]

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into this flourishing business sector, and among them, children. At first glance, one could see children in the mining sector mainly as victims entangled in the flows of raw materials of unbridled capitalism. But this paper aims to look at the often unconceivable, and as a result neglected, social agency of children even when they are involved in stigmatized and prohibited types of child labour. To do so, it relies on the results of a socio-anthropological collective research project on children’s mining activities which was carried out in a small locality called La Ruashi in the city of Lubumbashi (Province of Katanga). The article aims to provide a more comprehensive understanding of what is often normatively only labelled as ‘child labour’ by looking at different spheres of social relations within which children are embedded. Examining the set of social interactions that children have with their families, the broader community and their ‘peers’, several ‘family portraits’ are offered, highlighting a heterogeneity of social interpretations regarding this ‘new’ form of child work. It will be shown that for families from middle-class background, this kind of work is often socially disruptive, at the forefront of inter-generational conflict. As for families from lower classes, social changes induced by children’s mining activities are often better incorporated into the family habitus. Common social changes encountered in all families irrespective of class belonging will also be portrayed, showing the transversal societal impact these ‘new’ forms of child economic activities can provoke at a micro level. [less ▲]

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See detailSens et signification dans l'esthétique de Mallarmé
Durand, Pascal ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (in press), 5

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See detailThe effects of vitamin D on skeletal muscle strength, muscle mass and muscle power: a systematic review and meta-analysis of randomized controlled trials.
Beaudart, Charlotte ULg; Buckinx, Fanny ULg; Rabenda, Véronique ULg et al

in The Journal of clinical endocrinology and metabolism (in press)

Context There is growing evidence that vitamin D plays a role on several tissues including skeletal muscle. Objective To summarize with a meta-analyse the effects of vitamin D supplementation on muscle ... [more ▼]

Context There is growing evidence that vitamin D plays a role on several tissues including skeletal muscle. Objective To summarize with a meta-analyse the effects of vitamin D supplementation on muscle function. Data sources A systematic research of randomized controlled trials, performed between 1966 and January 2014 has been conducted on Medline, Cochrane Database of Systematics Reviews, Cochrane Central Register of Controlled and completed by a manual review of the literature and congressional abstracts. Study selection All forms and doses of vitamin D supplementation, with or without calcium supplementation, compared with placebo or control were included. Out of the 225 potentially relevant articles, 30 randomized controlled trials involving 5615 individuals (mean age: 61.1 years) met the inclusion criteria. Data extraction Data were extracted by two independent reviewers. Data synthesis Results revealed a small but significant positive effect of vitamin D supplementation on global muscle strength with a standardized mean difference (SMD) of 0.17 (p=0.02). No significant effect was found on muscle mass (SMD 0.058; p=0.52) or muscle power (SMD 0.057; p=0.657). Results on muscle strength were significantly more important with people who presented a 25-hydroxyvitamin D level <30 nmol/L. Supplementation seems also more effective on people aged 65 years or older compared to younger subjects (SMD 0.25; 95% CI 0.01 to 0.48 versus SMD 0.03; 95% CI -0.08 to 0.14). Conclusions Vitamin D supplementation has a small positive impact on muscle strength but additional studies are needed to define optimal treatment modalities, including dose, mode of administration and duration. [less ▲]

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See detailHydroxymethylfurfural: a possible emergent cause of honey bee mortality?
Zirbes, Lara ULg; Nguyen, Bach Kim ULg; de Graaf, DC et al

in Journal of Agricultural and Food Chemistry (in press)

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See detailGaucher Disease and Bone Manifestations
Marcucci, Gemma; Zimran, Ari; Bembi, Bruno et al

in Calcified tissue international (in press)

Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lysosomal enzyme glucocerebrosidase. Gaucher disease affects multiple organs, among which is the skeleton ... [more ▼]

Gaucher disease is a relatively rare metabolic disease caused by the inherited deficiency of the lysosomal enzyme glucocerebrosidase. Gaucher disease affects multiple organs, among which is the skeleton. Bone involvement occurs frequently in Gaucher disease, and is one of its most debilitating features, reducing the quality of life of patients. Bone status is an important consideration for treatment to ameliorate symptoms and reduce the risk of irreversible complications. We have conducted a systematic review of all the various aspects of Gaucher disease, focusing on different skeletal manifestations, pathophysiology of bone alterations, clinical symptoms, and current diagnostic and therapeutic approaches. [less ▲]

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See detailOne injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's knee
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in The Journal of sports medicine and physical fitness (in press)

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]

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See detailSinging ability is rooted in vocal-motor control of pitch
Hutchins, Sean; Larrouy, Pauline ULg; Peretz, Isabelle

in Attention, Perception & Psychophysics (in press)

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and ... [more ▼]

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and vocal production, they have failed to control for the timbre of the target to be matched. In the present study, we compare pitch matching accuracy with an unfamiliar instrument (the slider) and with the voice, designed such that the slider plays back recordings of the participant’s own voice. We also measured pitch accuracy in singing a familiar melody (“Happy Birthday”) to assess the relationship between single pitch matching tasks and melodic singing. Our results showed that participants (all nonmusicians) were significantly better at matching recordings of their own voices with the slider than with their voice, indicating that vocal-motor control is an important limiting factor on singing ability. We also found significant correlations between the ability to sing a melody in tune and vocal pitch matching, but not instrumental pitch matching. Better melodic singers also tended to have higher quality voices (as measured by acoustic variables). These results provide important evidence about the ultimate causes of poor singing ability, and demonstrate that single pitch matching tasks can be useful in measuring general singing abilities. [less ▲]

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See detailInternal encoding style and schizotypy: towards a conceptually-driven account of positive symptoms
Belayachi, Sanaa ULg; Laloyaux, Julien ULg; Laroi, Frank ULg et al

in Journal of Personality Disorders (in press)

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven ... [more ▼]

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven and conceptually-driven processing. A chronic imbalance between these two sources of stimulus encoding is likely to be maladaptive and could underlie cognitive and behavioral disturbances similar to that observed in schizotypy, especially if the balance is tipped too far towards conceptually-driven processing (i.e., Internal encoding style). This study aimed to examine the relationships between encoding style and various dimensions of schizotypy, by using a questionnaire that evaluates the extent to which pre-existing schemata (versus cues from the outside world) affect encoding processes. Consistent with previous findings, our results revealed that both Cognitive-Perceptual and Disorganization dimensions were related to an internal mode of encoding, suggesting that individuals with these features may be characterized by a disposition to biases at early stages of encoding. [less ▲]

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See detailInternational assessment of future low flow regimes and their impact on three water related sectors in the Meuse basin – a collaborative approach
Bauwens, Alexandra; Degré, Aurore ULg; Deraedt, Deborah ULg et al

in International Journal of River Basin Management (in press)

There is a wide recognition of the watershed scale as the right scale for global water management, notably in the context of the WFD. Hence, it often refers to international management and therefore to ... [more ▼]

There is a wide recognition of the watershed scale as the right scale for global water management, notably in the context of the WFD. Hence, it often refers to international management and therefore to various pre-existing regional management tools, models or even objectives. In this study we aim at describing the collaborative assessment of climate change’s effect on low flow regime and the consequences on three water related sectors: drinking water production, agriculture and electricity production. The paper highlights the choices that were made during the study that involved scientific teams, managers and stakeholders from the four main countries of the Meuse Basin. It shows that the methodological choices were operational and aimed at preserving existing methods and knowledge within each country. They led to hydrological scenarios comparable to the main available ensemble approaches and to methodologies well accepted within the concerned countries. The results of the project highlight and quantify the water scarcity that the three sectors will have to face by the end of the century mainly regarding the electricity production. They also show that common allocation rules are necessary to manage water demand during future low flow periods. [less ▲]

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See detailNégocier une majorité politique et devenir bourgmestre en Belgique. Quelles influences des droits régionaux ?
Grandjean, Geoffrey ULg

in Revue Régionale de Droit [= RRD] (in press)

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la ... [more ▼]

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la négociation d’une majorité politique et la désignation des bourgmestres en Belgique ? Afin de répondre à cette question, des entretiens semi-directifs ont été réalisés avec plusieurs bourgmestres et échevin issus de communes localisées dans les trois Régions. Des différences entre Régions mais également au sein de celles-ci ont été relevées. Les dispositions relatives au mode de désignation du bourgmestre sont primordiales pour comprendre les dynamiques de négociations politiques. Au final, cet article tisse les liens entre les normes juridiques et les jeux des acteurs politiques. [less ▲]

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See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

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See detailNatural killer and dendritic cells collaborate in the immune response induced by the vaccine against uterine cervical cancer.
Langers, Inge ULg; Renoux, Virginie; Reschner, Anca et al

in European journal of immunology (in press)

Virus-like particles (VLPs) of human papillomavirus (HPV) are used as a vaccine against HPV-induced cancer, and recently we have shown that these VLPs are able to activate natural killer (NK) cells. Since ... [more ▼]

Virus-like particles (VLPs) of human papillomavirus (HPV) are used as a vaccine against HPV-induced cancer, and recently we have shown that these VLPs are able to activate natural killer (NK) cells. Since NK cells collaborate with dendritic cells (DCs) to induce an immune response against viral infections and tumors, we studied the impact of this crosstalk in the context of HPV vaccination. NK cells in the presence of HPV-VLPs enhanced DC maturation as shown by an upregulation of CD86 and HLA-DR and an increased production of IL-12p70, but not of the immunosuppressive cytokine IL-10. This activation was bi-directional. Indeed, in the presence of HPV-VLPs, DCs further activated NK cells by inducing the upregulation of cell surface activation markers (CD69 and HLA-DR). The function of NK cells was also improved as shown by an increase in IFN-gamma secretion and cytotoxic activity against an HPV+ cell line. This crosstalk between NK cells and DCs needed CD40 interaction and IL-12p70 secretion, whereas NKG2D was not implicated. Our results provide insight into how VLPs interact with innate immune cells and how NK cells and DCs play a role in the immune response induced by this vaccine agent. This article is protected by copyright. All rights reserved. [less ▲]

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See detailDeliberate metaphors in political discourse: the case of citizen discourse
Perrez, Julien ULg; Reuchamps, Min

in Metaphorik (in press)

This article proposes to apply Steen’s (2008) 3D model of metaphor analysis in communication to a corpus of political discourse, in this case citizen discourse. Our corpus has accordingly been analysed by ... [more ▼]

This article proposes to apply Steen’s (2008) 3D model of metaphor analysis in communication to a corpus of political discourse, in this case citizen discourse. Our corpus has accordingly been analysed by making a distinction between three layers of metaphor, respectively at the linguistic (direct vs. indirect metaphors), conceptual (novel vs. conventional metaphors) and communicative levels (deliberate vs. non-deliberate metaphors). Our results suggest that making the distinction between deliberate and non-deliberate metaphors lead to meaningful political insights, notably pointing to differences in saliency of the source domains in terms of which citizens make sense of Belgian federalism. In this regard, the family domain, and more especially the metaphor BELGIAN FEDERALISM IS A LOVE RELATIONSHIP appears to function as an important conceptual reference point for the citizens’ understanding of the political relations in the Belgian context. [less ▲]

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See detailRelevance of accelerated conditions for the study of monoethanolamine degradation in post-combustion CO2 capture.
Léonard, Grégoire ULg; Toye, Dominique ULg; Heyen, Georges ULg

in Canadian Journal of Chemical Engineering (in press)

Solvent degradation represents one of the main operational drawbacks of the post-combustion CO2 capture process. Degradation not only induces additional costs for solvent make-up, it also impacts the ... [more ▼]

Solvent degradation represents one of the main operational drawbacks of the post-combustion CO2 capture process. Degradation not only induces additional costs for solvent make-up, it also impacts the process efficiency and its environmental penalty due to the emission of various degradation products. There is still a gap of knowledge about the influence of process operating conditions on degradation, making it currently impossible to predict the solvent degradation rate in CO2 capture plants. Morever, the reaction mechanisms corresponding to solvent degradation are very slow, significantly complicating its study in industrial units. In the present work, appropriate experimental equipment and analytical methods are developed for accelerating the degradation of monoethanolamine solvents (MEA). The relevance of accelerated conditions is established by comparing artificially degraded solvent samples with degraded solvent samples from industrial CO2 capture pilot plants. Two approaches are evaluated implying either discontinuous or continuous gas feed, this latest being the most representative of industrial degradation. The respective influences of the gas feed composition and the gas-liquid transfer are evidenced and quantified. Finally, the present study leads to a better understanding of solvent degradation in the CO2 capture process with MEA. More generally, it also evidences that accelerated conditions at laboratory-scale may provide relevant information for the study of slow phenomena taking place in large-scale industrial processes. Further works include the development of a kinetic model for MEA solvent degradation and the extension of this methodology to other promising solvents in order to facilitate the operation and large-scale deployment of CO2 capture. [less ▲]

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See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone haelth: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

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See detailÀ propos de deux pièges en psychopathologie
Englebert, Jérôme ULg

in Le Cercle Herméneutique (in press), 22

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See detailIdentification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people.
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Couffignal, Vincent et al

in Clinical physiology and functional imaging (in press)

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]

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See detailLevallois et Gravettien
Otte, Marcel ULg; Noiret, Pierre ULg

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]

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See detaillES CHUTES DE LA PERSONNE AGEE
GILLAIN, Sophie ULg; ELBOUZ, Leila ULg; Beaudart, Charlotte ULg et al

in Revue Médicale de Liège (in press)

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See detailA European survey on attitudes towards pain and end-of-life issues in locked-in syndrome
Demertzi, Athina ULg; Jox, Ralf J; Racine, Eric et al

in Brain Injury (in press)

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]

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See detailSouthern Ocean CO2 sink: The contribution of the sea ice
Delille, Bruno ULg; Vancoppenolle, M; Geilfus, N.-X. et al

in Journal of Geophysical Research. Oceans (in press)

We report first direct measurements of the partial pressure of CO2 (pCO2) within Antarctic pack sea ice brines and related CO2 fluxes across the air-ice interface. From late winter to summer, brines ... [more ▼]

We report first direct measurements of the partial pressure of CO2 (pCO2) within Antarctic pack sea ice brines and related CO2 fluxes across the air-ice interface. From late winter to summer, brines encased in the ice change from a CO2 large over-saturation, relative to the atmosphere, to a marked under-saturation while the underlying oceanic waters remains slightly oversaturated. The decrease from winter to summer of pCO2 in the brines is driven by dilution with melting ice, dissolution of carbonate minerals crystals and net primary production. As the ice warms, its permeability increases, allowing CO2 transfer at the air-sea ice interface. The sea ice changes from a transient source to a sink for atmospheric CO2. We upscale these observations to the whole Antarctic sea-icesea ice cover using the NEMO-LIM3 large-scale sea ice-ocean, and provide first estimates of spring and summer CO2 uptake from the atmosphere by Antarctic sea ice. Over the spring-summer period, the Antarctic sea-icesea ice cover is a net sink of atmospheric CO2 of 0.029 PgC, about 58% of the estimated annual uptake from the Southern Ocean. Sea ice then contributes significantly to the sink of CO2 of the Southern Ocean. [less ▲]

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See detailMetacognitive components in learning to learn approaches
Frenkel, Stéphanie ULg

in International Journal of Psychology : A Biopsychosocial Approach (in press)

Background. Numerous students are having school difficulties linked to the way they learn. Some people speak of a “metacognitive deficit”. We refer to a “sleeping potential” instead. Be it psychologists ... [more ▼]

Background. Numerous students are having school difficulties linked to the way they learn. Some people speak of a “metacognitive deficit”. We refer to a “sleeping potential” instead. Be it psychologists, teachers or parents, all wish to develop their skills in order to help these students. This is the case in primary and secondary school. The EDUCA + project is intended to provide possible solutions. Purpose. The aim of this paper is to present a metacognitive and cognitive theory of learning to learn, which will (a) explain why numerous students are having school difficulties, and (b) predict the success of the EDUCA + project. [less ▲]

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See detailEvaluation of the impact of 6-month training by whole body vibration on the risk of falls among nursing home residents, observed over a 12-month period: a single blind, randomized controlled trial.
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Maquet, Didier ULg et al

in Aging Clinical & Experimental Research (in press)

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement ... [more ▼]

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. OBJECTIVE: The objective of the present study was to evaluate the impact of 6-month training by WBV on functional and motor abilities among nursing home residents observed over a 12-month period. METHODS: Patients were randomized into two groups: the WBV group which received three training sessions every week composed of five series of 15 s of vibration at 30 Hz intensity for a period of 6 months and a control group with normal daily life. The impact of this training on the risk of falls was assessed blindly after 6 and 12 months by the Tinetti Test, the "Timed Up and Go" test and a quantitative evaluation of a 10-s walk performed with a tri-axial accelerometer. The occurrence of falls was also observed. RESULTS: 62 elderly healthy volunteers, (47 women and 15 men, mean age 83.2 +/- 7.9 years) were included in this study. There was no significant difference between the two groups regarding the Tinetti test (p = 0.75), the "Timed Up and Go" test (p = 0.19) and the Locometrix(R) test, except for the step length, measured by dual task (p < 0.01). No significant inter-group difference in the frequency of falls was observed during the 12 months of research. A total of 42 falls were recorded during the first 6 months of experimentation: 24 falls in the treated group and 18 in the control group (p = 0.60). During the next 6 months, 19 falls occurred: 8 falls in the treated group and 11 in the control group (p = 0.52). CONCLUSION: This study failed to establish the effectiveness of low doses of WBV, under the conditions used in our study, on functional and motor abilities of institutionalized elderly patients. However, given the positive results of other studies, further investigations, with modified therapeutic protocols, seem necessary to clarify the effects of WBV in the elderly. [less ▲]

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See detailCompte-rendu de l'ouvrage de Pierre RICHÉ, Être enfant au Moyen Âge
Close, Florence ULg

in Moyen Age (Le) (in press)

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See detailCompte rendu de G. TOUSSAINT, Kreuz und Knochen. Reliquien zur Zeit der Kreuzzüge, Berlin, 2011.
George, Philippe ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailClinical and biological determinants of sclerostin plasma concentration in hemodialysis patients
DELANAYE, Pierre ULg; KRZESINSKI, Jean-Marie ULg; Warling, Xavier et al

in Nephron. Clinical Practice (in press)

Background: Sclerostin is a potent inhibitor of bone formation, but the meaning of its serum levels remains undetermined. We evaluated the association between sclerostin levels and clinical or biological ... [more ▼]

Background: Sclerostin is a potent inhibitor of bone formation, but the meaning of its serum levels remains undetermined. We evaluated the association between sclerostin levels and clinical or biological data in hemodialyzed patients (HD), notably parathormone (PTH), biomarkers of bone turnover, vascular calcifications and mortality after 2 years. Methods: 164 HD patients were included in this observational study. The calcification score was assessed with the Kauppila method. Patients were followed for 2 years. Results: Median sclerostin levels were significantly (p < 0.0001) higher in HD versus healthy subjects (n = 94) (1,375 vs. 565 pg/ml, respectively). In univariate analysis a significant association (p < 0.05) was found between sclerostin and age, height, dialysis vintage, albumin, troponin, homocysteine, PTH, C-terminal telopeptide of collagen type I, bone-specific alkaline phosphatase and osteoprotegerin, but not with the calcification score. In a multivariate model, the association remained with age, height, dialysis vintage, troponin, homocysteine, phosphate, PTH, but also with vascular calcifications. Association was positive for all variables, except PTH and vascular calcifications. The baseline sclerostin concentration was not different in survivors and non-survivors. Conclusions: We confirm a higher concentration of sclerostin in HD patients, a positive association with age and a negative association with PTH. A positive association with phosphate, homocysteine and troponin calls for additional research. The clinical interest of sclerostin to assess vascular calcifications in HD is limited and no association was found between sclerostin and mortality. [less ▲]

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See detailBrain metabolic dysfunction in Capgras delusion during Alzheimer’s disease: a positron emission tomography study
Jedidi, Haroun ULg; Daury, Noémy; Rémi, Capa et al

in American Journal of Alzheimer's Disease & Other Dementias (in press)

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since ... [more ▼]

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since little is known regarding the neural correlates of Capgras syndrome, the cerebral metabolic pattern of a patient with probable Alzheimer’s disease (AD) and Capgras syndrome was compared with those of 24 healthy elderly subjects and 26 AD patients without delusional syndrome. Compared to the healthy and AD groups, the patient had significant hypometabolism in frontal and posterior midline structures. In light of current neural models of face perception, our patient’s Capgras syndrome may be related to impaired recognition of a familiar face, subserved by the posterior cingulate/precuneus cortex, and impaired reflection about personally relevant knowledge related to a face, subserved by the dorsomedial prefrontal cortex. [less ▲]

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See detailOn the asymptotic standard error of a class of robust estimators of ability in dichotomous item response models
Magis, David ULg

in British Journal of Mathematical & Statistical Psychology (in press)

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods ... [more ▼]

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods were introduced to lessen the impact of such aberrant responses onto the estimation process. The computation of asymptotic (i.e., large sample) standard errors (ASE) for these robust estimators, however, has not been fully considered yet. This paper focuses on a broad class of robust ability estimators, defined by an appropriate selection of the weight function and the residual measure, for which the ASE is derived from the theory of estimating equations. The maximum likelihood (ML) and the robust estimators, together with their estimated ASE, are then compared through a simulation study. It is concluded that both the estimators and their ASE perform similarly in absence of response disturbances, while the robust estimator and its estimated ASE are less biased and outperform their ML counterparts in presence of response disturbances with large impact on the item response process. [less ▲]

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See detailA global analysis of Spitzer and new HARPS data confirms the loneliness and metal-richness of GJ 436 b
Lanotte, Audrey ULg; Gillon, Michaël ULg; Demory, B.-O. et al

in Astronomy and Astrophysics (in press)

Context. GJ 436b is one of the few transiting warm Neptunes for which a detailed characterisation of the atmosphere is possible, whereas its non-negligible orbital eccentricity calls for further ... [more ▼]

Context. GJ 436b is one of the few transiting warm Neptunes for which a detailed characterisation of the atmosphere is possible, whereas its non-negligible orbital eccentricity calls for further investigation. Independent analyses of several individual datasets obtained with Spitzer have led to contradicting results attributed to the different techniques used to treat the instrumental effects. Aims. We aim at investigating these previous controversial results and developing our knowledge of the system based on the full Spitzer photometry dataset combined with new Doppler measurements obtained with the HARPS spectrograph. We also want to search for additional planets. Methods. We optimise aperture photometry techniques and the photometric deconvolution algorithm DECPHOT to improve the data reduction of the Spitzer photometry spanning wavelengths from 3-24 {\mu}m. Adding the high precision HARPS radial velocity data, we undertake a Bayesian global analysis of the system considering both instrumental and stellar effects on the flux variation. Results. We present a refined radius estimate of RP=4.10 +/- 0.16 R_Earth, mass MP=25.4 +/- 2.1 M_Earth and eccentricity e= 0.162 +/- 0.004 for GJ 436b. Our measured transit depths remain constant in time and wavelength, in disagreement with the results of previous studies. In addition, we find that the post-occultation flare-like structure at 3.6 {\mu}m that led to divergent results on the occultation depth measurement is spurious. We obtain occultation depths at 3.6, 5.8, and 8.0 {\mu}m that are shallower than in previous works, in particular at 3.6 {\mu}m. However, these depths still appear consistent with a metal-rich atmosphere depleted in methane and enhanced in CO/CO2, although perhaps less than previously thought. We find no evidence for a potential planetary companion, stellar activity, nor for a stellar spin-orbit misalignment. [ABRIDGED] [less ▲]

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See detailDépister la fragilité, un bénéfice pour le patient et pour le soignant
RICOUR, Céline ULg; DESAINTHUBERT, Marie; GILLAIN, Sophie ULg et al

in Revue Médicale de Liège (in press)

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See detailCorporate Disclosures, Information Asymmetry and Stock-Market Liquidity in France
Sougné, Danielle ULg; Ajina, Aymen; Lakhal, Faten

in Journal of Applied Business Research (in press)

This paper aims at studying the effect of corporate disclosures on information asymmetry and stock-market liquidity in France. Specifically, the purpose of this paper is to highlight the importance of ... [more ▼]

This paper aims at studying the effect of corporate disclosures on information asymmetry and stock-market liquidity in France. Specifically, the purpose of this paper is to highlight the importance of information included in the annual reports on investor’s behavior. This is proxied by the information asymmetry component of the bid-ask spread and stock market liquidity. Our sample includes 196 French listed firms over a period ranging from 2004 to 2007. We opt for an explanatory study using OLS regressions to examine the nature of the relationship between information disclosed in annual reports and bid-ask spreads a proxy for information asymmetry and stock market liquidity. The results show that the extent of corporate disclosures in annual reports positively influences the liquidity of the French market and negatively affects the adverse selection component of the bid-ask spread. This effect is further confirmed by the commitment to IFRS by French-listed firms from 2005. The decomposition of the total score in the sub-indices shows that non-financial and financial information are important in trading decisions while strategic information may be attractive only for long-term positions [less ▲]

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See detailGenetic parameters for mid-infrared methane indicators based on milk fatty acids in dairy cows
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

in Journal of Applied Animal Research (in press)

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not ... [more ▼]

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not currently available. The mid-infrared (MIR) prediction of milk fatty acids is relevant in this context. Five MIR methane indicators were derived from the literature and were calibrated from 600 samples analyzed by gas chromatography. Genetic parameters for these traits were estimated using single trait random regression test-day models from 619,265 records collected from 2007 to 2011 on 71,188 Holstein cows in their first three lactations. For the published indicator showing the highest relationship with the methane data (R2 = 0.88), the average daily heritability was 0.34±0.01, 0.37±0.01 and 0.34±0.01 for the first three lactations, respectively. The methane emission (g/day) was increased from beginning of lactation, reached at the highest in peak of lactation and decreased towards end of lactation. The largest differences between estimated breeding values (EBV) of sires having daughters in production eructing the highest and the lowest methane content was 21.80, 22.75 and 24.89 kg per lactation for the first three parities. Positive genetic correlations were estimated between indicator traits and milk fat and protein content. Low negative correlation was observed with milk yield. In conclusion, this study shows the feasibility to predict methane indicator traits by MIR. Moreover, the estimated genetic parameters suggest also a potential genetic variability of the quantity of methane eructed by dairy cows. [less ▲]

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See detailL'intentionnalité cognitive et ses modes. Reinach critique de Brentano
Dewalque, Arnaud ULg

in Philosophie (in press)

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai ... [more ▼]

Dans cet article, je suggère que la théorie reinachienne du jugement peut être vue comme une contribution à une théorie générale de l’intentionnalité cognitive et de ses modes. À cette fin, je focaliserai mon attention sur certaines divergences significatives entre Reinach et Brentano. Après quelques réflexions introductives (§§ 1-2), j’examinerai plus exactement les questions suivantes : quels sont les motifs théoriques qui ont conduit Reinach à s’écarter de la théorie brentanienne du jugement (§§ 3-4) ? Et que retenir de ses analyses aujourd’hui (§§ 5-6) ? [less ▲]

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See detailIn situ bidentate to tetradentate ligand exchange reaction in cobalt-mediated radical polymerization
Kermagoret, Anthony ULg; Jérôme, Christine ULg; Detrembleur, Christophe ULg et al

in European Polymer Journal (in press)

Organometallic-mediated radical polymerization (OMRP) has seen a significant growth in the last years notably due to the development of new metal complexes, especially cobalt derivatives. Despite of this ... [more ▼]

Organometallic-mediated radical polymerization (OMRP) has seen a significant growth in the last years notably due to the development of new metal complexes, especially cobalt derivatives. Despite of this, none of the reported complexes offers optimal control for monomers with very different reactivity, which somewhat limits the synthesis of copolymers. In order to expand the scope of cobalt-mediated radical polymerization (CMRP), we investigated an in situ ligand exchange reaction for modulating the properties of the cobalt complex at the polymer chain-end and adjusting the C-Co bond strength involved in the control process. With the aim of improving the synthesis of poly(vinyl acetate)-b-poly(n-butyl acrylate) copolymers, bidentate acetylacetonate ligands, which impart high level of control to the polymerization of vinyl acetate (VAc), were replaced in situ at the PVAc-cobalt chain-end by tetradentate Salen type ligands that are more suited to acrylates. [less ▲]

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See detailA reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).
Hiligsmann, Mickaël ULg; Cooper, Cyrus; Guillemin, Francis et al

in Seminars in arthritis and rheumatism (in press)

BACKGROUND: General recommendations for a reference case for economic studies in rheumatic diseases were published in 2002 in an initiative to improve the comparability of cost-effectiveness studies in ... [more ▼]

BACKGROUND: General recommendations for a reference case for economic studies in rheumatic diseases were published in 2002 in an initiative to improve the comparability of cost-effectiveness studies in the field. Since then, economic evaluations in osteoarthritis (OA) continue to show considerable heterogeneity in methodological approach. OBJECTIVES: To develop a reference case specific for economic studies in OA, including the standard optimal care, with which to judge new pharmacologic and non-pharmacologic interventions. METHODS: Four subgroups of an ESCEO expert working group on economic assessments (13 experts representing diverse aspects of clinical research and/or economic evaluations) were charged with producing lists of recommendations that would potentially improve the comparability of economic analyses in OA: outcome measures, comparators, costs and methodology. These proposals were discussed and refined during a face-to-face meeting in 2013. They are presented here in the format of the recommendations of the recently published Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement, so that an initiative on economic analysis methodology might be consolidated with an initiative on reporting standards. RESULTS: Overall, three distinct reference cases are proposed, one for each hand, knee and hip OA; with diagnostic variations in the first two, giving rise to different treatment options: interphalangeal or thumb-based disease for hand OA and the presence or absence of joint malalignment for knee OA. A set of management strategies is proposed, which should be further evaluated to help establish a consensus on the "standard optimal care" in each proposed reference case. The recommendations on outcome measures, cost itemisation and methodological approaches are also provided. CONCLUSIONS: The ESCEO group proposes a set of disease-specific recommendations on the conduct and reporting of economic evaluations in OA that could help the standardisation and comparability of studies that evaluate therapeutic strategies of OA in terms of costs and effectiveness. [less ▲]

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See detailMultiscale variability of amphipod assemblages in Posidonia oceanica meadows
Sturaro, Nicolas ULg; Lepoint, Gilles ULg; Vermeulen, Simon et al

in Journal of Sea Research (in press)

The study of spatial patterns is of ecological importance in order to understand the causes of the distribution and abundance of organisms, and it also provides valuable basis for management and ... [more ▼]

The study of spatial patterns is of ecological importance in order to understand the causes of the distribution and abundance of organisms, and it also provides valuable basis for management and conservation. Amphipod crustaceans are key organisms in seagrass ecosystems. However, little attention has been paid to the spatial scales at which amphipod assemblages may vary. We examined variability patterns of amphipod populations inhabiting Posidonia oceanica meadows, over spatial scales spanning four orders of magnitude (1 to 1000 metres) and for two consecutive years. This study reports the scales that contributed most to spatial variation of amphipod assemblages and explores the potential processes of the observed patterns, with particular emphasis on habitat features. The number of species, the diversity and the density of some species, exhibited high variation across years. Most species showed the highest spatial variation in density and biomass at small scales (~1 and 10 m). Based on density data, the structure of amphipod assemblages did not differ at any scales investigated. The patchiness that occurred at small scales may have been only weakly related to habitat features. Instead, we postulated that behavioural processes of amphipods were likely good explanatory factors. Although, the small scale spatial variability can be an important feature of amphipod assemblages in P. oceanica meadows, many patterns probably remained undetected as they may occur at scales smaller than those investigated. [less ▲]

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See detailA note on the equivalence between observed and expected information functions with polytomous IRT models
Magis, David ULg

in Journal of Educational & Behavioral Statistics (in press)

The purpose of this note is to study the equivalence of observed and expected (Fisher) information functions with polytomous item response theory (IRT) models. It is established that observed and expected ... [more ▼]

The purpose of this note is to study the equivalence of observed and expected (Fisher) information functions with polytomous item response theory (IRT) models. It is established that observed and expected information functions are equivalent for the class of divide-by-total models (including partial credit, generalized partial credit, rating scale and nominal response models), but not for the class of difference models (including the graded response and modified graded response models). Yet, observed information function remains positive in both classes. Straightforward connections with dichotomous IRT models and further implications are outlined. [less ▲]

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See detailEstimated daily intake and cumulative risk assessment of phthalate diesters in a Belgian general population
Dewalque, Lucas ULg; Charlier, Corinne ULg; PIRARD, Catherine ULg

in Toxicology Letters (in press)

The daily intakes (DI) were estimated in a Belgian general population for 5 phthalates, namely diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), di-iso-butyl phthalate (DiBP), butylbenzyl phthalate ... [more ▼]

The daily intakes (DI) were estimated in a Belgian general population for 5 phthalates, namely diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), di-iso-butyl phthalate (DiBP), butylbenzyl phthalate (BBzP) and di-2-ethylhexyl phthalate (DEHP), based on the urinary measurements of their corresponding metabolites. DI values ranged between <LOD and 59.65 μg/kg bw/day depending on the congener, and were globally higher for children than adults. They were compared to acceptable levels of exposure (tolerable daily intakes) to evaluate the hazard quotients (HQ), which highlight an intake above the dose considered as safe for values greater than 1. If very few of our Belgian participants exceeded this threshold for phthalates considered individually, 6.2% of the adults and 25% of the children showed an excessive hazard index (HI) which took into account the cumulative risk of adverse anti-androgenic effects. These results are of concern since these HI were based on only 3 phthalates (DEHP, DiBP and DnBP), and showed a median of 0.55 and 0.29 for children and adults respectively. The comparison with previously determined dietary intakes demonstrated that for DEHP, food intake was nearly the only route of exposure while other pathways occurred mainly for the other studied phthalates. [less ▲]

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See detailEffet du mode de conservation d’huile de Jatropha curcas L. sur son efficacité dans la lutte contre les principaux insectes ravageurs du niébé (Vigna unguiculata (L.) Walp. au Niger
Abdoul Habou, zakari; Toudou, Adam; Haubruge, Eric ULg et al

in Tropicultura (in press)

Jatropha curcas oil has an insecticidal activity harnessed by the farmers in Niger. In this study, we compared the insecticidal activity of two batches of oil conserved during 70 days, one exposed to ... [more ▼]

Jatropha curcas oil has an insecticidal activity harnessed by the farmers in Niger. In this study, we compared the insecticidal activity of two batches of oil conserved during 70 days, one exposed to light and the other kept in the dark. The insecticidal efficacy was evaluated in a field with three concentrations (5, 10 and 15%) trial on the main pests of Cowpea (Vigna unguiculata (L.) Walp) and in a laboratory test on Megalurothrips sjostedti Trybon (Thysanoptera: Thripidae) with different concentrations of crude oil (50; 100; 150 and 200 µl). No difference in insecticidal effect was found between the two modes of oil conservation, both in the laboratory and in the field. In the field, regardless of the mode of conservation, the concentrations of 10% of J. curcas oil enables a reduction of over than 80% of thrips, aphids, and bugs compared to the control. Its increased seeds yield more than 50%. The concentration of 15% gives an insecticidal effect comparable to that of the reference treatment (deltaméthrine) but induces phytotoxicity symptoms on the leaves of Cowpea. [less ▲]

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