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See detailIsotopic tracing of sediment components that are assimilated by epibiontic juveniles of Holothuria scabra (Holothuroidea)
Plotieau, Thomas; Lepoint, Gilles ULg; Lavitra, Thiery et al

in Journal of the Marine Biological Association of the United Kingdom (in press)

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic ... [more ▼]

Despite H. scabra’s wide distribution and status as one of the best candidates for sustaining the development of tropical sea cucumber aquaculture, very few data are available regarding the organic fraction it assimilates in practice. In this study we report experimental results where H. scabra’s diet was supplemented with various 15N-labelled organic fractions of sediment. We used juveniles weighing between 38- 88 mg at the beginning of the experiment (ca. 2 cm long and 30 days old). Their growth was measured over a four week period and their 15N composition recorded. The results showed that H. scabra juveniles assimilated all added organic components from both dissolved and particulate fractions of the sediment. Bacteria seem to be an important food source for juveniles, even more so than microphytobenthos (diatoms). [less ▲]

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See detailNon-isothermal moisture balance equation in porous media: a review of mathematical formulations in Building Physics
Dubois, Samuel ULg; Lebeau, Frédéric ULg; Evrard, Arnaud ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Understanding heat and mass transfers in porous materials is crucial in many areas of scientific research. Mathematical models have constantly evolved, their differences lying mainly in the choice of the ... [more ▼]

Understanding heat and mass transfers in porous materials is crucial in many areas of scientific research. Mathematical models have constantly evolved, their differences lying mainly in the choice of the driving potentials used to describe moisture flows, as well as in the complexity of characterizing the physical phenomena involved. Models developed in the field of Building Physics (HAM models) are used to describe the behavior of envelope parts and assess their impact on user comfort and energy performance. The water balance equation can be described in many ways; it is a function of the boundary conditions considered and the fact they induce high or low water content in the porous materials used. This paper gives an overview of various formulations for this equation that are found in the Building Physics literature. It focuses first on the physically based formulation of moisture balance, drawing on the Representative Elementary Volume (REV) concept, coupled with thermodynamic flow rates description. This is then reformulated in line with various main moisture state variables offering a wide variety of expressions that are compared with available models. This approach provides access to all secondary transport coefficients associated with the process of mathematical transformation. Particular emphasis is placed on the moisture storage function choice and its impact on the final mathematical formulations. [less ▲]

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See detailThe Childhood Executive Function Inventory (CHEXI): Confirmatory Factor Analyses and Cross-Cultural Clinical Validity in a Sample of 8- to 11-Year-Old Children
Catale, Corinne ULg; Meulemans, Thierry ULg; Thorell, Lisa B.

in Journal of Attention Disorders (in press)

The Childhood Executive Functioning Inventory (CHEXI) is a new rating instrument for executive functioning developed by Thorell and Nyberg (2008). Through exploratory factor analyses, this inventory has ... [more ▼]

The Childhood Executive Functioning Inventory (CHEXI) is a new rating instrument for executive functioning developed by Thorell and Nyberg (2008). Through exploratory factor analyses, this inventory has been shown to tap into working memory and inhibition-related behaviors in young children. In this study, we present the psychometric characteristics of the French adaptation of the CHEXI in 8- to 11-year-old children. In addition, we explore the cross-cultural validity of the CHEXI in discriminating between children with ADHD and normally developing children in two culturally different samples (Belgian and Swedish). Confirmatory factor analyses replicated the two-factor solution, referred to as inhibition and working memory, that was identified in the original study with Swedish children. Supplementary analyses indicated that both subscales have good psychometric properties. From a clinical point of view, the CHEXI was found to discriminate, with high sensitivity and specificity, between children with ADHD and normally developing controls in both cultural samples. Cross-cultural clinical implications are discussed. [less ▲]

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See detailMonitoring of osteoporosis therapy
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Best Practice & Research. Clinical Endocrinology & Metabolism (in press)

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance ... [more ▼]

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance with these treatments is not optimal, and a number of patients could be considered as non-responders. Consequently, monitoring anti-osteoporotic therapy could be part of successful osteoporosis management. Currently, no formal well-accepted clinical practice guidelines are available for monitoring anti-osteoporosis therapies. Changes in bone mineral density and bone turnover markers, while on therapy, have potential value in monitoring treatment but their assessment and, consequently, their benefits could be limited by metrological and clinical issues. Moreover, their effectiveness is probably drug dependant. Recommendation for the standardisation of the methodology when analysing the potential relevance of tools for the monitoring of osteoporosis therapy is needed. [less ▲]

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See detailPIXE identification of the provenance of ferruginous rocks used by Neanderthals
Mathis, François ULg; Bodu, Pierre; Dubreuil, Olivier ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (in press)

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a ... [more ▼]

Les Bossats, near Ormesson, France, is a newly discovered late Mousterian open air site dated to around 47,000 years ago by thermoluminescence. The archaeological level, fossilized by loess, revealed a rich industry based on the discoid mode, associated with numerous fragments of red and yellow iron oxide-rich rocks showing clear traces of powder production (abrasion, striation, scraping), which are exceptional remains for this remote period. Archeological material and geological samples from the close environment were studied by PIXE and by petrographical observations made on thin sections. The geological sources were identified by means of PIXE analyses on two IBA facilities: AGLAE (2 MV tandem) at the C2RMF in Paris and the cyclotron of the IPNAS (University of Liège). We paid particular attention to the comparison of results obtained on both installations by using the same set of geological standards and by a fine evaluation of the limit of detection relative to each trace elements of interest for both experimental set ups. The elemental fingerprint of one geological source of iron-rich concretions corresponds clearly with the archaeological collection. At least, this investigation demonstrates that the colouring materials were minutely selected in the close neighbouring of the site by the Neanderthals. [less ▲]

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See detailDominant amphipods of Posidonia oceanica seagrass meadows display considerable trophic diversity
Michel, Loïc ULg; Dauby, Patrick ULg; Gobert, Sylvie ULg et al

in Marine Ecology (in press)

Gut content examination and trophic markers (fatty acids, stables isotopes of C and N) were combined to delineate the diet of the dominant species of amphipods from Mediterranean Posidonia oceanica ... [more ▼]

Gut content examination and trophic markers (fatty acids, stables isotopes of C and N) were combined to delineate the diet of the dominant species of amphipods from Mediterranean Posidonia oceanica seagrass meadows and to highlight trophic diversity among this community. Our results indicate that, although all dominant species heavily relied on macroalgal epiphytes, considerable interspecific dietary differences existed. Carbon stable isotope ratios notably showed that some of the amphipod species favored grazing on epiphytes from leaves or litter fragments (Apherusa chiereghinii, Aora spinicornis, Gammarus aequicauda), while others like Dexamine spiniventris preferred epiphytes from rhizomes. The remaining amphipods (Caprella acanthifera, Ampithoe helleri and Gammarella fucicola) readily consumed both groups. In addition, SIAR modeling suggested that most species had a mixed diet, and relied on several food items. Fatty acid analysis and gut contents revealed that contribution of microepiphytic diatoms and of benthic and suspended particulate organic matter to the diet of amphipods were anecdotal. None of the examined species seemed to graze on their seagrass host (low 18:2(n-6) and 18:3(n-3) fatty acids contents), but G. aequicauda partly relied on seagrass leaf detritus, as demonstrated by the lesser 13C-depletion of their tissues. Overall, our findings suggest that amphipods, because of their importance in transfers of organic matter from primary producers and detritus to higher rank consumers, are key-items in P. oceanica associated food webs. [less ▲]

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See detaillES CHUTES DE LA PERSONNE AGEE
GILLAIN, Sophie ULg; ELBOUZ, Leila ULg; Beaudart, Charlotte ULg et al

in Revue Médicale de Liège (in press)

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See detailThe role of olfaction in wireworms: a review on foraging behavior and sensory apparatus
Barsics, Fanny ULg; Haubruge, Eric ULg; Francis, Frédéric ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Introduction Integrated management of wireworms (Coleoptera: Elateridae) depends upon approaches applied both above- and belowground, and over several spatial scales. While foraging, these soil pests use ... [more ▼]

Introduction Integrated management of wireworms (Coleoptera: Elateridae) depends upon approaches applied both above- and belowground, and over several spatial scales. While foraging, these soil pests use biotic and abiotic signals to orientate towards target plant organs. Development of efficient techniques for implementation in integrated strategies relies upon improved knowledge of this process. In particular, an important step consists of elucidating the role of volatile organic compounds (VOC), emitted by belowground plant organs, in wireworm chemical ecology. This would have a positive impact on push-pull strategies and varietal selection developed against these insects. Literature In this work, we summarized the available data regarding wireworm foraging behavior as well as variables that should be considered when studying the potential role of plant-produced volatile semiochemicals. This includes CO2 gradients and other host-related cues, temperature, relative humidity and soil moisture, and wireworm physiological stage. We also review what is known of the sensory apparatus of wireworms, since this is involved in every step of the foraging process. Conclusion Some baseline data for studying VOC related wireworm foraging behavior exists. Using it as a tool in applied entomology should result in discovery of the semiochemicals that underpin trophic interactions involving these pests. However, most of the key pest species are not fully described with regards to the parameters detailed here. Obtaining accurate information to fill the current knowledge gaps will be needed in order to devise new integrated management strategies. [less ▲]

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See detailAIR VERSUS GROUND TRANSPORT OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: EXPERIENCE IN A RURAL-BASED HELICOPTER MEDICAL SERVICE
MOENS, Didier ULg; Stipulante, Samuel ULg; Donneau, Anne-Françoise ULg et al

in European Journal of Emergency Medicine (in press)

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We ... [more ▼]

Aims Primary pre-hospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in timely reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI). We designed a prospective study involving patients with acute myocardial infarction aimed at the evaluation of the potential benefit of such primary HEMS interventions as compared with classical EMS ground transport. Methods & results This prospective study was conducted from July 1, 2007 to June 15, 2012. Successive patients with ST-segment elevation myocardial infarction (STEMI) eligible for percutaneous coronary intervention (PCI) were included. Simulated ground-based access times were computed using a digital cartographic program, allowing the estimation of healthcare system delay from call to admission to the catheterisation laboratory. During the study period, 4485 patients benefited from HEMS activations. Of these patients, 342 (8%) suffering from STEMI were transferred for primary PCI. Median primary response time time was 11 min (IQR: 8 - 14 min) using the helicopter and 32 min (25 – 44 min) using road transport. Median transport time using HEMS was 12 min (9 – 15 min) and 50 min (36 – 56 min) by road. The median system delay using HEMS was 52 min (45 – 60 min), while this time was 110 min (95 – 126 min) by road. Finally, the system delay median gain was 60 min (47 – 72 min). Conclusions Using HEMS in a rural region allows STEMI patients to benefit from appropriate rescue care with similar delays as those seen in urban patients. [less ▲]

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See detailSome misunderstood or unknown tricks (X) (LaTeX)
Merciadri, Luca ULg

in TUGboat (in press)

This is the 10th edition of my TUGboat `Tips & Tricks.' This time, we shall first see how to write `dancing text,' roman numerals, how to draw under and over braces on same elements, and how to display ... [more ▼]

This is the 10th edition of my TUGboat `Tips & Tricks.' This time, we shall first see how to write `dancing text,' roman numerals, how to draw under and over braces on same elements, and how to display aligned (in)equations systems. We will then end by discussing on BibLaTeX and Biber, which constitute a promising alternative to BibTeX. [less ▲]

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See detailData processing of vibrational chemical imaging for pharmaceutical applications.
Sacre, Pierre-Yves ULg; De Bleye, Charlotte ULg; Chavez, Pierre-François ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (in press)

Vibrational spectroscopy (MIR, NIR and Raman) based hyperspectral imaging is one of the most powerful tools analyze pharmaceutical preparation. Indeed, it combines the advantages of vibrational ... [more ▼]

Vibrational spectroscopy (MIR, NIR and Raman) based hyperspectral imaging is one of the most powerful tools analyze pharmaceutical preparation. Indeed, it combines the advantages of vibrational spectroscopy to imaging techniques and allows therefore the visualization of distribution of compounds, crystallization processes. However, these techniques provide a huge amount of data that must be processed to extract the relevant information. This review presents fundamental concepts of hyperspectral imaging, the basic theory of the most used chemometric tools used to pre-process, process and post-process the generated data. The last part of the present paper focuses on pharmaceutical applications of hyperspectral imaging and highlights the data processing approaches to enable the reader making the best choice among the different tools available. [less ▲]

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See detailArsinoe II come dea attraverso le sue epiclesi cultuali
Caneva, Stefano ULg

in Athenaeum : Studii Periodici di Letteratura e Storia (in press)

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con ... [more ▼]

Dopo una introduzione storica e storiografica sul significato dei culti regali ellenistici, l’intervento esamina alcuni dei nomi divini attribuiti ad Arsinoe II nelle fonti letterarie e documentarie, con l’eccezione dell’epiclesi esclusiva Philadelphos. Scopo della ricerca è 1) una valutazione delle strategie di inserimento della nuova dea nel pantheon tradizionale; 2) una riflessione sull’autoconsapevolezza degli antichi in relazione alla propria tradizione religiosa, per come essa si manifesta attraverso l’oculata manipolazione di un elemento essenziale nella definizione della divinità, qual è il nome divino. Un’Appendice elenca, in tre tabelle, tutte le denominazioni greche di Arsinoe II (esclusa Philadelphos), fornendo indicazioni sulla fonte, la sua collocazione spaziale e temporale e sulla divinità tradizionale di riferimento. [less ▲]

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See detailGammapathie monoclonale de signification indéterminée : information destinée aux médecins référents
CAERS, Jo ULg; Binsfeld, Marilène ULg; Muller, Joséphine ULg et al

in Revue Médicale de Liège (in press)

Les gammapathies monoclonales de signification indéterminée (GMSI) sont fréquentes dans la population générale. Leur potentiel évolutif malin impose une surveillance clinique régulière et prolongée ... [more ▼]

Les gammapathies monoclonales de signification indéterminée (GMSI) sont fréquentes dans la population générale. Leur potentiel évolutif malin impose une surveillance clinique régulière et prolongée. Cependant, les GMSI forment un groupe très hétérogène et tous les patients n’ont pas le même risque de transformation maligne. Plusieurs critères biologiques simples, disponibles en routine ont été identifiés comme facteurs prédictifs de la transformation. Les scores prédictifs de transformation maligne combinant plusieurs de ces facteurs permettront probablement la classification des patients en fonction de leur risque évolutif. La prise en charge pourra ainsi être adaptée au risque individuel de chaque patient [less ▲]

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See detailMesoporous amorphous tungsten oxide electrochromic films: a Raman analysis of their good switching behavior
Chatzikyriakou, Dafni ULg; Krins, Natacha ULg; Gilbert, Bernard ULg et al

in Electrochimica Acta (in press)

The intercalation and de-intercalation of lithium cations in electrochromic tungsten oxide thin films are significantly influenced by their structural and surface characteristics. In this study, we ... [more ▼]

The intercalation and de-intercalation of lithium cations in electrochromic tungsten oxide thin films are significantly influenced by their structural and surface characteristics. In this study, we prepared two types of amorphous films via the sol-gel technique: one dense and one mesoporous in order to compare their response upon lithium intercalation and de-intercalation. According to chronoamperometric measurements, Li+ intercalates/de-intercalates faster in the mesoporous film (24s/6s) than in the dense film (48s/10s). The electrochemical measurements (cyclic voltammetry and chronoamperometry) also showed worse reversibility for the dense film compared to the mesoporous film, giving rise to important Li+ trapping and remaining coloration of the film. Raman analysis showed that the mesoporous film provides more accessible and various W-O surface bonds for Li+ intercalation. On the contrary, in the first electrochemical insertion and de-insertion in the dense film, Li+ selectively reacts with a few surface W-O bonds and preferentially intercalates into pre-existing crystallites to form stable irreversible LixWO3 bronze. [less ▲]

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See detailBayesian versus frequentist methods for estimating disease true prevalence and 4 diagnostic test performance
Sanogo, M; Abatih, E; Saegerman, Claude ULg

in Veterinary Journal (in press)

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See detailOne injection of platelet-rich plasma associated to a submaximal eccentric protocol to treat chronic jumper's knee
Kaux, Jean-François ULg; Croisier, Jean-Louis ULg; Bruyère, Olivier ULg et al

in The Journal of sports medicine and physical fitness (in press)

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons ... [more ▼]

INTRODUCTION: Jumper's knee is a frequent chronic overuse syndrome of the upper part of the patellar tendon. Platelets contain lots of growth factors which could enhance the healing process of tendons. METHODS: Twenty patients with chronic upper patellar tendinopathy were enrolled. Assessments were made before infiltration of PRP, and 6 weeks and 3 months after the infiltration, using a 10--point Visual Analogic Scale, clinical examinations with a pressure algometer, algofunctional scores (IKDC and VISA--P), functional assessments (isokinetic and optojump evaluations) and imagery (ultrasounds and MRI). The PRP was obtained with an apheresis system (COM.TEC, Fresenius). Six millilitres of PRP were injected without local anaesthetic. One week after infiltration, patients started a standardised sub--maximal eccentric reeducation. RESULTS: Pain during daily activities significantly decreased with time. During functional evaluation, it decreased as well, but without significant functional improvement. No improvements in the imagery measurements were observed. Younger patients seemed to be more susceptible to have an improvement of pain by the PRP infiltration. CONCLUSION: This study demonstrates that a local infiltration of PRP associated with a submaximal eccentric protocol can improve symptoms of chronic jumper's knee in patients non--responsive to classical conservative treatments. [less ▲]

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See detailEffect of bovine colostrum intake on growth, reproductive parameters and survival in red kids
Harouna, Abdou; Marichatou, Hamani; Beckers, Jean-François ULg et al

in Journal of Animal Physiology & Animal Nutrition (in press)

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition ... [more ▼]

The aim of this study is to evaluate the efficacy of frozen Azawak colostrum supplementation on body weight (BW), average daily gain (ADG), reproductive parameters (mean age at first parturition, fertility, fecundity, prolificacy) and mortality rate among red kids. The study was conducted at the goat farm secondary centre of Maradi in Niger from September 2010 to September 2011. The control animals (n = 20) were left with their mother, while the treatment animals (n = 20) received in addition 50 ml/animal/day of bovine colostrum at birth and 15 ml/animal/day from d2 to d15. Weight was measured weekly from birth to d365. Mortalities were also recorded over the same period. For reproductive parameters, observations began at weaning (d197). Growth rate was higher (p < 0.001) in supplemented animal, and the treatment effects on ADG were observed up to 150 day after the end of supplementation. A similar long-lasting trend was also observed in relation to the mortality rate (25% for ColG vs. 55% for ConG; p = 0.05). The age at first kidding tended to be lower in the treated group (13.8 0.7 vs. 14.1 0.8 month; p < 0.1). In conclusion, mild bovine colostrum supplementation induces a long-lasting positive impact on growth rate and to a lower extent on reproduction parameters and survival rate. [less ▲]

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See detailExpression microarray as a tool to identify candidate blood biomarkers in horses suffering from inflammatory airway disease
Ramery, Eve ULg; Fraipont, Audrey ULg; Art, Tatiana ULg et al

in Veterinary Clinical Pathology (in press)

Background: Inflammatory airway disease (IAD) affects performance and well-being in horses. Diagnosis is primarily reached by bronchoalveolar lavage (BAL) cytology but this is invasive and requires ... [more ▼]

Background: Inflammatory airway disease (IAD) affects performance and well-being in horses. Diagnosis is primarily reached by bronchoalveolar lavage (BAL) cytology but this is invasive and requires sedation. Objectives: The purpose of this study was to identify candidate blood biomarkers of IAD using species-specific expression microarrays. Methods: Horse Gene Expression Microarrays were used to investigate global mRNA expression in circulating leukocytes from healthy and IAD-affected standardbreds and endurance horses. Results: Nine genes were significantly differentially regulated in standardbreds and 61 in endurance horses (P < 0.001). These genes were mainly related to inflammation (eg. ALOX15B, PLA2G12B and PENK), oxidant/antioxidant balance (eg. DUOXA2 and GSTO1-1) and stress (eg. V1aR, GRLF1, Homer-2 and MAOB). DUOXA2, ALOX15B, PLA2G12B, MAOB and GRLF1 variations of expression were further validated by RT-qPCR. The deregulation of the oxidant/antioxidant balance was demonstrated at the protein level by an increase of glutathione peroxidase (GPx) activity in heparinised whole blood of IAD-affected standardbreds (P = 0.0025) and endurance horses (P = 0.0028). There was good correlation (r = 0.7354) between BAL neutrophil percentage and whole blood GPx activity in all horses. Conclusions: There is accumulating evidence that, even when systemic clinical signs are not evident, circulating leukocyte gene expression can reflect responses of other tissues, leading to potential diagnostic applications in the future. Although not specific for IAD, whole blood GPx activity appears to reflect BAL neutrophil percentage. This finding should be further assessed by testing a larger number of horses. [less ▲]

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See detailÉtude des contraintes mécaniques locomotrices chez le cheval
Noble, Prisca ULg; Collin, Bernard ULg; Denoix, Jean-Marie et al

in Annales de Médecine Vétérinaire (in press)

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some ... [more ▼]

In locomotor biomechanics, three high groups of contraints are commonly encountared : pressure, traction and torsion. In supra-maximal conditions, all of these contraints would be responsible of some equine diseased locomotor systems. In order to understand better the contraints in the equine locomotor dynamics, some investigations have been carried out. Moreover, some measurement methods, based on the mechanics of Newton, have been performed. This review shows the different measurement techniques and introduces the mechanical basis that are compulsory for the understanding of the equine locomotor apparatus functioning. [less ▲]

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See detailLa première interprétation heideggérienne de la Monadologie
Pieron, Julien ULg

in Philosophie (in press)

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See detailDabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Douxfils, Jonathan; Buckinx, Fanny ULg; Mullier, Francois et al

in Journal of the American Heart Association (in press)

BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of ... [more ▼]

BACKGROUND: Signals of an increased risk of myocardial infarction (MI) have been identified with dabigatran etexilate in randomized controlled trials (RCTs). METHODS AND RESULES: We conducted searches of the published literature and a clinical trials registry maintained by the drug manufacturer. Criteria for inclusion in our meta-analysis included all RCTs and the availability of outcome data for MI, other cardiovascular events, major bleeding, and all-cause mortality. Among the 501 unique references identified, 14 RCTs fulfilled the inclusion criteria. Stratification analyses by comparators and doses of dabigatran etexilate were conducted. Peto odds ratio (ORPETO) values using the fixed-effect model (FEM) for MI, other cardiovascular events, major bleeding, and all-cause mortality were 1.34 (95% CI 1.08 to 1.65, P=0.007), 0.93 (95%CI 0.83 to 1.06, P=0.270), 0.88 (95% CI 0.79 to 0.99, P=0.029), and 0.89 (95% CI 0.80 to 1.00, P=0.041). When compared with warfarin, ORPETO values using FEM were 1.41 (95% CI 1.11 to 1.80, P=0.005), 0.94 (95%CI 0.83 to 1.06, P=0.293), 0.85 (95% CI 0.76 to 0.96, P=0.007), and 0.90 (95% CI 0.81 to 1.01, P=0.061), respectively. In RCTs using the 150-mg BID dosage, the ORPETO values using FEM were 1.45 (95% CI 1.11 to 1.91, P=0.007), 0.95 (95% CI 0.82 to 1.09, P=0.423), 0.92 (95% CI 0.81 to 1.05, P=0.228), and 0.88 (95% CI 0.78 to 1.00, P=0.045), respectively. The results of the 110-mg BID dosage were mainly driven by the RE-LY trial. CONCLUSIONS: This meta-analysis provides evidence that dabigatran etexilate is associated with a significantly increased risk of MI. This increased risk should be considered taking into account the overall benefit in terms of major bleeding and all-cause mortality. [less ▲]

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See detailA review of inversion techniques related to the use of relationship matrices in animal breeding
Faux, Pierre ULg; Gengler, Nicolas ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

In animal breeding, prediction of genetic effects is usually obtained through the use of mixed models. For any of these genetic effects, mixed models require the inversion of the covariance matrix ... [more ▼]

In animal breeding, prediction of genetic effects is usually obtained through the use of mixed models. For any of these genetic effects, mixed models require the inversion of the covariance matrix associated to that effect, which is equal to the associated relationship matrix times the associated component of the genetic variance. Given the size of many genetic evaluation systems, computing the inverses of these relationship matrices is not trivial. In this review, we aim to cover computational techniques that ease inversion of relationship matrices used in animal breeding for prediction of the following different types of genetic effects: additive effect, gametic effect, effect due to presence of marked quantitative trait loci, dominance effect and different epistasis effects. Construction rules and inversion algorithms are detailed for each relationship matrix. In the final discussion, we draw up a common theoretical frame to most of the reviewed techniques. Two computational constraints come out of this theoretical frame: setting up the matrix of dependencies between levels of the effect and setting up some parts (diagonal or block-diagonal elements) of the relationship matrix to be inverted. [less ▲]

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See detailFirst ‘in situ’ determination of gas transport coefficients (DO2, DAr and DN2 ) from bulk gas 2 concentration measurements (O2, N2, Ar) in natural sea ice
Crabeck, O.; Delille, Bruno ULg; Rysgaard, S. et al

in Marine Chemistry (in press)

We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5 ... [more ▼]

We report bulk gas concentrations of O2, N2 and Ar, as well as their transport coefficients, in natural landfast subarctic sea ice in southwest Greenland. The observed bulk ice gas composition was 27.5% O2, 71.4% N2 and 1.09% Ar. Most previous studies suggest that convective transport is the main driver of gas displacement in sea ice and have neglected diffusion processes. According to our data, brines were stratified within the ice, so that no convective transport could occur within the brine system. Therefore, diffusive transport was the main driver of gas migration. By analysing the temporal evolution of an internal gas peak within the ice, we deduced the bulk gas transport coefficients for oxygen (DO2), argon (DAr) and nitrogen (DN222 ). The values fit to the few existing estimates from experimental work, and are close to the diffusivity values in water (10-5 cm2 s-124 ). We suggest that gas bubbles escaping from the brine to the atmosphere - as the ice gets more permeable during melt could be responsible for the previously reported high transport coefficients. These results underline that when there is no convective transport within the sea ice, the transport of gas by diffusion through the brines, either in the liquid or gaseous phases, is a major factor in controlling the ocean–atmosphere exchange. [less ▲]

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See detailCircadian and circannual variations in cord blood hematopoietic cell composition
Servais, Sophie ULg; BAUDOUX, Etienne ULg; Brichard, B. et al

in Haematologica (in press)

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See detailDifferences in species–area relationships among the major lineages of land plants: a macroecological perspective
Patino Llorente, Jairo ULg; Weigelt, P.; Guilhaumon, F. et al

in Global Ecology & Biogeography (in press)

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See detailClinical pattern characterisation of cattle naturally infected by BTV-8 - Clinical characterisation of BTV-8 infected cattle
Zanella, G; Martinelle, Ludovic ULg; Guyot, Hugues ULg et al

in Transboundary and Emerging Diseases (in press)

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See detail“How are you Vulnerable?”: Using Participation for Vulnerability Analysis in Emergency Planning
Rossignol, Nicolas ULg; Turcanu, Catrinel; Fallon, Catherine ULg et al

in Journal of Risk Research (in press)

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science ... [more ▼]

Scientists in many fields of research have developed models, theories and concepts attempting to grasp and manage dangers that are often difficult to imagine. Among the different perspectives, the Science and Technology Studies (STS) Vulnerability Approach seems very promising. Relying on a constructivist paradigm, it is based on an inductive collection and analysis of a wide range of factors, with a particular focus on cultural factors and actual day-to-day practices. In this paper, we present the roots of this approach and we display findings based on three case studies exploring emergency planning in three different contexts (a city near a SEVESO plant, a school near a nuclear plant, and a city confronted to multiple catastrophic scenarios). The cases studies were realized by conducting three Focus Groups with different types of stakeholders (citizens, teachers, firemen, decision makers, etc.). After presenting the results of the case studies, we discuss how stakeholders’ participation can inform such type of vulnerability analysis in the context of emergency planning. We argue that participation fosters a deep understanding of actual safety governance practices which allows innovative results to emerge as well as it initiates a learning process among the participants. It contributes to questioning the relations between decision-makers, experts and citizens. It has the potential of bypassing the positivist and quantitative rationale of safety, and thus, of redefining the vulnerability governance. As a conclusion, we question the role of such STS vulnerability approach within the actual vulnerability governance. [less ▲]

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See detailThe open-air site of Tolbor 16 (Northern Mongolia): preliminary results and perspectives
Zwyns, N.; Gladyshev; Gunchinsuren, B. et al

in Quaternary International (in press)

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See detailSome misunderstood or unknown tricks (XIII) (LaTeX)
Merciadri, Luca ULg

in TUGboat (in press)

We will here again consider many tips and tricks. This time, they will mostly come from Glad Deschrijver, TeX Tricks, 2011. (http://users.ugent.be/~gdschrij/LaTeX/textricks.html.) Tricks: vertically ... [more ▼]

We will here again consider many tips and tricks. This time, they will mostly come from Glad Deschrijver, TeX Tricks, 2011. (http://users.ugent.be/~gdschrij/LaTeX/textricks.html.) Tricks: vertically aligned itemize environments, allowing linebreaks after comma in math mode, writing under and over elements, and using stacks, footnotes with a new number at each section, footnotes in tabular, splitting algorithm environments on multiple pages, let " produce opening/closing quotation marks, indenting some text but not the first line, using diagonal dots positioned according to the opposite diagonal, using a centered verbatim environment, drawing a table with dashed lines, shaded cells and arrows pointing at a row and a column, correct spacing around square brackets (used for sets) in math mode. [less ▲]

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See detailDo aphids actively search for ant partners?
Fischer, Christophe ULg; Vanderplanck, Maryse; Lognay, Georges ULg et al

in Insect Science (in press)

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is ... [more ▼]

The aphid–ant mutualistic relationships are not necessarily obligate for neither partners but evidence is that such interactions provide them strong advantages in terms of global fitness. While it is largely assumed that ants actively search for their mutualistic partners namely using volatile cues; whether winged aphids (i.e. aphids’ most mobile form) are able to select ant-frequented areas had not been investigated so far. Ant-frequented sites would indeed offer several advantages for these aphids including a lower predation pressure through ant presence and enhanced chances of establishing mutuaslistic interactions with neighbour ant colonies. In the field, aphid colonies are often observed in higher densities around ant nests, which is probably linked to a better survival ensured by ants’ services. Nevertheless, this could also result from a preferential establishment of winged aphids in ant-frequented areas. We tested this last hypothesis through different ethological assays and show that the facultative myrmecophilous black bean aphid, Aphis fabae L., does not orientate its search for a host plant preferentially towards ant-frequented plants. However our results suggest that ants reduce the number of winged aphids leaving the newly colonized plant. Thus, ants involved in facultative myrmecophilous interactions with aphids appear to contribute to structure aphid populations in the field by ensuring a better establishment and survival of newly established colonies rather than by inducing a deliberate plant selection by aphid partners based on the proximity of ant colonies. [less ▲]

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See detailSur Capitalisme, désir et servitude. Lettre à Frédéric Lordon
Pieron, Julien ULg

in Dissensus (in press), 6(printemps 2014),

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See detailSome misunderstood or unknown tricks (XI) (LaTeX) and encoding issues (II)
Merciadri, Luca ULg

in TUGboat (in press)

Three subjects will be detailed: 1. Using LaTeX syntax as an unambiguous way to communicate, 2. Writing a bold \ell, 3. Fonts' encodings.

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See detailPhénoménologie brentanienne
Dewalque, Arnaud ULg

in Austriaca (in press)

Mon ambition est de mettre en lumière quelques traits distinctifs du programme d’analyse de l’esprit développé par Franz Brentano et les membres de son école. Plus spécialement, je suggérerai qu’il y a un ... [more ▼]

Mon ambition est de mettre en lumière quelques traits distinctifs du programme d’analyse de l’esprit développé par Franz Brentano et les membres de son école. Plus spécialement, je suggérerai qu’il y a un sens à parler d’une authentique phénoménologie brentanienne. J’entends par là un programme de recherche original, distinct notamment de la phénoménologie de Husserl – qui, à partir de 1903, n’est plus conçue comme une psychologie empirique ni, a fortiori, comme une psychologie expérimentale – et de la « phénoménologie » de Stumpf – qui, se rattachant à la tradition plus ancienne d’une Empfindungslehre, désigne exclusivement l’étude des phénomènes sensibles ou des matériaux sensoriels . Ma conviction est qu’un examen attentif des caractéristiques propres à la phénoménologie ou psychologie descriptive d’inspiration brentanienne est une bonne manière de donner un sens à l’expression de « phénoménologie autrichienne » qui a été proposée, dans la littérature, pour désigner le champ d’investigation ouvert par Brentano et les brentaniens. [less ▲]

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See detailContribution à un lexique épigraphique: "deltographéma"
Famerie, Etienne ULg

in Zeitschrift für Papyrologie und Epigraphik (in press)

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See detailUne tablette scolaire copte de Lecce : TUL inv. C 1
Carlig, Nathan ULg; Delattre, Alain

in Studi di Egittologia e di Papirologia (in press)

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See detailOn the pragmatics of subjectification. The emergence and grammaticalization of a verb-less Allative Future in Ancient Egyptian
Grossman, Eitan; Polis, Stéphane ULg

in Acta Linguistica Hafniensia : International Journal of Linguistics (in press)

In this paper, we argue that an expanded conception of the distinction between speaker-oriented and subject-oriented inferences is crucial for understanding the motivations and mechanisms of semantic ... [more ▼]

In this paper, we argue that an expanded conception of the distinction between speaker-oriented and subject-oriented inferences is crucial for understanding the motivations and mechanisms of semantic change in grammaticalization and subjectivation, on the one hand, and for clarifying the links between semantic change and reductive formal changes. Speaker-oriented inferences have significant consequences, leading to the relaxation of selectional restrictions on a construction. In turn, the relaxation of selectional restrictions can create conditions in which the type- and token-frequency of a construction can rise considerably. Furthermore, changes in the selectional restrictions on a construction can themselves catalyze semantic change by coercing listeners into new form-function pairings. This framework is applied to the grammaticalization of allative futures, a typological comparative concept developed in order to compare structurally diverse future tenses. A small typological study allows us to reconsider some problematic pathways of grammaticalization and to suggest some alternative analyses. Following the typological discussion, a detailed diachronic case study of a verbless allative future in Ancient Egyptian is presented. [less ▲]

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See detailOn the accuracy of adults’ auditory perception of normophonic and dysphonic children’s personality.
Verduyckt, Ingrid; Remacle, Marc; Morsomme, Dominique ULg

in Logopedics, Phoniatrics, Vocology (in press)

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP ... [more ▼]

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (N=57) were asked to infer the personality of normophonic (NP) children and children with VFN (N=10) on the basis of vowels and sentences. The auditory inferred profiles were compared to the actual personality of NP and VFN children. Positive and partly accurate inferences of VFN children’s personality were made on the basis of connected speech, while sustained vowels yielded negative and inaccurate inferences of personality traits of children with VFN. Dysphonic voice quality, as defined by the overall severity of vocal abnormality, conveyed inaccurate and low degrees of Extraversion. This effect was counterbalanced in connected speech by faster speaking rate that accurately conveyed higher degrees of Extraversion, a characteristic trait of VFN children’s actual personality. [less ▲]

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See detailNégocier une majorité politique et devenir bourgmestre en Belgique. Quelles influences des droits régionaux ?
Grandjean, Geoffrey ULg

in Revue Régionale de Droit [= RRD] (in press)

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la ... [more ▼]

Depuis 2001, les Régions sont compétentes en matière d’organisation et d’élection des pouvoirs locaux. Elles ont adopté des règles différentes. Dans quelle mesure ces règles influencent-elles la négociation d’une majorité politique et la désignation des bourgmestres en Belgique ? Afin de répondre à cette question, des entretiens semi-directifs ont été réalisés avec plusieurs bourgmestres et échevin issus de communes localisées dans les trois Régions. Des différences entre Régions mais également au sein de celles-ci ont été relevées. Les dispositions relatives au mode de désignation du bourgmestre sont primordiales pour comprendre les dynamiques de négociations politiques. Au final, cet article tisse les liens entre les normes juridiques et les jeux des acteurs politiques. [less ▲]

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See detailLes défis colossaux auxquels la santé publique va devoir faire face !
COUCKE, Philippe ULg

in Onco : Revue Multidisciplinaire d'Oncologie (in press)

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See detailStochastic modelling of reservoir sedimentation in a semi-arid watershed
Adam, Nicolas; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Water Resources Management (in press)

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real ... [more ▼]

Sedimentation in large reservoirs is a major concern in semi-arid regions characterized by severe seasonal water scarcity. As a contribution to improved sediment management, this study analyses the real case of the reservoir of Sidi Yacoub in the north of Algeria. First, a dynamic model of the reservoir was set up and used to estimate past water and sediment inflows (period 1990-2010) based on data recorded by the dam operator and measurements at a gauging station located downstream of the reservoir. Second, in a stochastic framework using the statistical characteristics of inflow and outflow discharges, a projection of future sedimentation was performed until 2030, assuming stationarity of the statistical distributions. Third, the model was used to investigate the influence of possible climate change and to quantify the positive effects of soil conservation measures upstream. [less ▲]

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See detailGenetic parameters for mid-infrared methane indicators based on milk fatty acids in dairy cows
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

in Journal of Applied Animal Research (in press)

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not ... [more ▼]

Dairy production is identified as a major source of methane (CH4) emissions. Selective breeding canbe one method used to mitigate CH4 emissions but practical and cheap measurement of this trait is not currently available. The mid-infrared (MIR) prediction of milk fatty acids is relevant in this context. Five MIR methane indicators were derived from the literature and were calibrated from 600 samples analyzed by gas chromatography. Genetic parameters for these traits were estimated using single trait random regression test-day models from 619,265 records collected from 2007 to 2011 on 71,188 Holstein cows in their first three lactations. For the published indicator showing the highest relationship with the methane data (R2 = 0.88), the average daily heritability was 0.34±0.01, 0.37±0.01 and 0.34±0.01 for the first three lactations, respectively. The methane emission (g/day) was increased from beginning of lactation, reached at the highest in peak of lactation and decreased towards end of lactation. The largest differences between estimated breeding values (EBV) of sires having daughters in production eructing the highest and the lowest methane content was 21.80, 22.75 and 24.89 kg per lactation for the first three parities. Positive genetic correlations were estimated between indicator traits and milk fat and protein content. Low negative correlation was observed with milk yield. In conclusion, this study shows the feasibility to predict methane indicator traits by MIR. Moreover, the estimated genetic parameters suggest also a potential genetic variability of the quantity of methane eructed by dairy cows. [less ▲]

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See detailSouthern Ocean CO2 sink: The contribution of the sea ice
Delille, Bruno ULg; Vancoppenolle, M; Geilfus, N.-X. et al

in Journal of Geophysical Research. Oceans (in press)

We report first direct measurements of the partial pressure of CO2 (pCO2) within Antarctic pack sea ice brines and related CO2 fluxes across the air-ice interface. From late winter to summer, brines ... [more ▼]

We report first direct measurements of the partial pressure of CO2 (pCO2) within Antarctic pack sea ice brines and related CO2 fluxes across the air-ice interface. From late winter to summer, brines encased in the ice change from a CO2 large over-saturation, relative to the atmosphere, to a marked under-saturation while the underlying oceanic waters remains slightly oversaturated. The decrease from winter to summer of pCO2 in the brines is driven by dilution with melting ice, dissolution of carbonate minerals crystals and net primary production. As the ice warms, its permeability increases, allowing CO2 transfer at the air-sea ice interface. The sea ice changes from a transient source to a sink for atmospheric CO2. We upscale these observations to the whole Antarctic sea-icesea ice cover using the NEMO-LIM3 large-scale sea ice-ocean, and provide first estimates of spring and summer CO2 uptake from the atmosphere by Antarctic sea ice. Over the spring-summer period, the Antarctic sea-icesea ice cover is a net sink of atmospheric CO2 of 0.029 PgC, about 58% of the estimated annual uptake from the Southern Ocean. Sea ice then contributes significantly to the sink of CO2 of the Southern Ocean. [less ▲]

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See detailConcentration, Activity and Biochemical Characterization of Myeloperoxidase in Fresh and Post-thaw equine semen and their Implication on Freezability
Ponthier, Jérôme ULg; Franck, Thierry ULg; Parrilla Hernandez, Sonia ULg et al

in Reproduction in Domestic Animals (in press)

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and ... [more ▼]

Myeloperoxidase (MPO) is a pro-oxidant enzyme associated with decreased motility in thawed equine semen. This study aimed to describe MPO concentration, activity and subunits in raw and thawed semen and to correlate these data with motilities in raw and thawed semen. Semen samples from five stallions were collected four times. Motilities were assessed in raw and thawed semen. MPO assays were performed in raw seminal plasma, raw sperm-rich pellet and thawed semen. Total and active MPO concentrations were, respectively, assayed by enzyme-linked immunosorbent assay and specific immunological extraction followed by enzymatic detection. MPO subunits present in semen were characterized by Western 3 blot. Purified active MPO was added in PBS and freezing extender to control its activity during freezing procedure. Differences between medians were determined using Kruskal– Wallis test, and correlations were determined using Spearman’s test for nonparametric data. Active MPO concentration was low in seminal plasma and thawed semen, but high in pellet (p = 0.0058), as the opposite relation was observed for total MPO concentration (p < 0.0001). In seminal plasma and post- thaw semen, inactive 86-kDa MPO precursor was mainly observed. Purified MPO activity was decreased in the extender (p = 0.0286). MPO activity in pellet was highly correlated with thawed progressive motility (r = 􏰑0.5576, p = 0.0086). Inac- tive MPO precursor and unknown low molecular weight inactive MPO precursor subunits explain low MPO activity in semen. Major MPO activity was observed in pellet, and post- thaw loss of activity is partially explained by MPO inactiva- tion in extender. Thawed semen motility was negatively correlated with MPO activity in pellet, becoming a potential freezability predictor. [less ▲]

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See detailSpinoza contre Spinoza: l'antihumanisme de Lordon, un althussérisme?
Mancuso, Eva ULg

in Dissensus (in press), 6

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See detailAn ecological study of Electra posidoniae Gautier, 1954 (Cheilostomata, Anasca), a bryozoan epiphyte solely found on the seagrass Posidonia oceanica (L.) Delile, 1813
Lepoint, Gilles ULg; Mouchette, Olivier; Pelaprat, Corine et al

in Belgian Journal of Zoology (in press)

The bryozoan Electra posidoniae Gautier is found solely on the leaves of the Neptune grass Posidonia oceanica (L.) Delile, dominating the leaf epifauna of this seagrass. Epiphytes of marine angiosperms ... [more ▼]

The bryozoan Electra posidoniae Gautier is found solely on the leaves of the Neptune grass Posidonia oceanica (L.) Delile, dominating the leaf epifauna of this seagrass. Epiphytes of marine angiosperms (or seagrasses) often play an important role in ecosystem functioning, for example as food web suppliers. As dysfunction of epiphytic compartment is often implied in human-induced seagrass decline, it is important to understand the dynamics and life traits of this community in pristine areas. This study involved the monthly assessment of colonization dynamics, biomass seasonality and diet composition through stable isotopes measurements of E. posidoniae at a depth of 10 m in the Revellata Bay (Corsica, Mediterranean Sea). Ancestrulae (i.e. colony founders) appeared towards the end of winter and were very selective in their settlement position along the P. oceanica leaves. A maximum of 100,000 colonies per square meter was recorded. E. posidoniae colonies dominated the epiphytic community biomass in early spring, and were over-covered by epiphytic algae in June. Food shortage could be also involved in this decrease. Although stable isotope ratios of C, N and S showed that this suspension feeder mainly relies on the water column productivity for its food, other food sources such as re-suspended epiphytic diatoms could be important in late spring (i.e. after the phytoplanktonic bloom). Additionally, a contribution of seagrass phytodetritus to the diet of this species cannot be excluded. The species was almost absent in winter, raising the question of its recruitment in spring. This study confirms the quantitative importance of this species in the seagrass meadow and explores its role in the relationship between the water column and this seagrass ecosystem. [less ▲]

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See detailChild labour, Agency and Family dynamics: The Case of Mining in Katanga (DRC)
Andre, Géraldine ULg; Godin, Marie

in Childhood (in press)

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into ... [more ▼]

In the last three decades, the development of the artisanal and small-scale mining (ASM) sector has been increasing in the Democratic Republic of Congo (DRC), bringing more and more urban families into this flourishing business sector, and among them, children. At first glance, one could see children in the mining sector mainly as victims entangled in the flows of raw materials of unbridled capitalism. But this paper aims to look at the often unconceivable, and as a result neglected, social agency of children even when they are involved in stigmatized and prohibited types of child labour. To do so, it relies on the results of a socio-anthropological collective research project on children’s mining activities which was carried out in a small locality called La Ruashi in the city of Lubumbashi (Province of Katanga). The article aims to provide a more comprehensive understanding of what is often normatively only labelled as ‘child labour’ by looking at different spheres of social relations within which children are embedded. Examining the set of social interactions that children have with their families, the broader community and their ‘peers’, several ‘family portraits’ are offered, highlighting a heterogeneity of social interpretations regarding this ‘new’ form of child work. It will be shown that for families from middle-class background, this kind of work is often socially disruptive, at the forefront of inter-generational conflict. As for families from lower classes, social changes induced by children’s mining activities are often better incorporated into the family habitus. Common social changes encountered in all families irrespective of class belonging will also be portrayed, showing the transversal societal impact these ‘new’ forms of child economic activities can provoke at a micro level. [less ▲]

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See detailAn algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Bruyère, Olivier ULg; Cooper, C; Pelletier, JP et al

in Seminars in Arthritis & Rheumatism (in press)

Objectives: Existing practice guidelines for osteoarthritis (OA) analyze the evidence behind each proposed treatment but do not prioritize the interventions in a given sequence. The objective was to ... [more ▼]

Objectives: Existing practice guidelines for osteoarthritis (OA) analyze the evidence behind each proposed treatment but do not prioritize the interventions in a given sequence. The objective was to develop a treatment algorithm recommendation that is easier to interpret for the prescribing physician based on the available evidence and that is applicable in Europe and internationally. The knee was used as the model OA joint. Methods: ESCEO assembled a task force of 13 international experts (rheumatologists, clinical epidemiologists, and clinical scientists). Existing guidelines were reviewed; all interventions listed and recent evidence were retrieved using established databases. A first schematic flow chart with treatment prioritization was discussed in a 1-day meeting and shaped to the treatment algorithm. Fine-tuning occurred by electronic communication and three consultation rounds until consensus. Results: Basic principles consist of the need for a combined pharmacological and non-pharmacological treatment with a core set of initial measures, including information access/education, weight loss if overweight, and an appropriate exercise program. Four multimodal steps are then established. Step 1 consists of background therapy, either non-pharmacological (referral to a physical therapist for re-alignment treatment if needed and sequential introduction of further physical interventions initially and at any time thereafter) or pharmacological. The latter consists of chronic Symptomatic Slow-Acting Drugs for OA (e.g., prescription glucosamine sulfate and/or chondroitin sulfate) with paracetamol at-need; topical NSAIDs are added in the still symptomatic patient. Step 2 consists of the advanced pharmacological management in the persistent symptomatic patient and is centered on the use of oral COX-2 selective or non-selective NSAIDs, chosen based on concomitant risk factors, with intra-articular corticosteroids or hyaluronate for further symptom relief if insufficient. In Step 3, the last pharmacological attempts before surgery are represented by weak opioids and other central analgesics. Finally, Step 4 consists of end-stage disease management and surgery, with classical opioids as a difficult-to-manage alternative when surgery is contraindicated. Conclusions: The proposed treatment algorithm may represent a new framework for the development of future guidelines for the management of OA, more easily accessible to physicians. © 2014 The Authors. [less ▲]

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See detailIdentification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people.
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Couffignal, Vincent et al

in Clinical physiology and functional imaging (in press)

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among ... [more ▼]

INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies. [less ▲]

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See detailLa maladie de Lyme entre cadrage infectieux, vectoriel et zoonotique : vers une écologisation des problèmes sanitaires ?
Massart, Clémence ULg

in VertigO : la Revue Electronique en Sciences de l'Environnement (in press)

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ... [more ▼]

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ricinus en Europe ; Ixodes persulcatus en Asie ; Ixodes scapularis aux États-Unis et au Canada). Les médecins et les malades ont d’abord développé un cadrage infectieux, ancré dans la santé humaine, réservé à Lyme et soumis à une vive controverse. Progressivement, un second cadrage vectoriel s’est structuré autour des entomologistes médicaux puis des écologues, généralement étrangers à la problématique des maladies humaines. Axé sur le vecteur, ce cadrage englobe les autres maladies transmises par Ixodes ricinus en Europe qui, durant les 30 dernières années, n’ont cessé d’être découvertes : bartonnelles, babésioses, tularémie, encéphalite à tiques, etc. Combinée à ces nouvelles pathologies, la notoriété de Lyme a finalement contribué à ouvrir la catégorie « transmission vectorielle » – traditionnellement associée aux moustiques des pays tropicaux – aux tiques et aux maladies de l’hémisphère nord qu’elles véhiculent. Un troisième cadrage axé sur les réservoirs et qualifié de zoonotique commence enfin à se dessiner. Il faut reconnaître dans cette juxtaposition des cadrages – infectieux, vectoriel et zoonotique – une forme d’écologisation des problèmes sanitaires. [less ▲]

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See detailSome misunderstood or unknown LaTeX tricks (XIV) and LaTeX learning curve
Merciadri, Luca ULg

in TUGboat (in press)

We will here give three tricks: i. using a personalized \overline, ii. boxing every digit of an integer, iii. using \scalebox. I will then expose my point of view about the LaTeX learning curve, and give ... [more ▼]

We will here give three tricks: i. using a personalized \overline, ii. boxing every digit of an integer, iii. using \scalebox. I will then expose my point of view about the LaTeX learning curve, and give some of the most common beginners’ mistakes. [less ▲]

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See detailComposantes métacognitives ; Définitions et outils d’évaluation
Frenkel, Stéphanie ULg

in Enfance : Psychologie, Pédagogie, Neuropsychiatrie, Sociologie (in press)

Many tools have been developed since the 1970s in order to assess metacognition and its first implementations. Over time, questionnaires, tests, interviews, observations, computer programmes, and other ... [more ▼]

Many tools have been developed since the 1970s in order to assess metacognition and its first implementations. Over time, questionnaires, tests, interviews, observations, computer programmes, and other methods have become more and more based on self-regulated learning theories. At the same time, for the last fifteen years or so, the number of students with learning difficulties linked to the way they learn seems to be increasing slowly but steadily. Therefore, it seems essential to enable these learners develop a more efficient learning behaviour. Similarly, we see that professional field workers are increasingly asking for efficient and adapted tools in this field. The purpose of this paper is twofold: it provides a review of the above-mentioned assessment tools, and it discusses them in order to contribute to the creation of new tools with a wider scope. Following an analysis of the abundant literature on the subject, two classifications were developed. Thirty-five tools were kept and categorised: first, according to a developmental perspective (preschool, primary school, secondary school and/or adult), second, according to the metacognitive component they assess (metacognitive knowledge, strategies and/or experiences). However, no existing tool covers the whole period of compulsory education. Moreover, in order to assess the learners’ metacognitive abilities fully, it is necessary to combine online and offline assessments in concrete situations. There are still some needs to be met in this regard. [less ▲]

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See detailFernand De Visscher et la Société Internationale d'Histoire des Droits de l'Antiquité
Gerkens, Jean-François ULg

in Revue Historique de Droit Français et Etranger [=RHD] (in press)

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See detailGlycine receptors control the generation of projection neurons in the developing cerebral cortex
Avila, Ariel; Vidal, P.M.; Tielens, Sylvia ULg et al

in Cell Death & Differentiation (in press)

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See detailRésolution de problèmes mathématiques et développement de compétences : comment soutenir les élèves dans leur apprentissage ? Editorial.
Fagnant, Annick ULg; Marcoux, Géry; Vlassis, Joëlle

in Cahiers des Sciences de l'Education (Les) (in press), 36

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See detailInfluence of noise correction on intra- and inter-subject variability of quantitative metrics in diffusion kurtosis imaging
André, Elodie ULg; Grinberg, Farida; Farrher, Ezequiel et al

in PLoS ONE (in press)

Diffusion kurtosis imaging (DKI) is a promising extension of diffusion tensor imaging, giving new insights into the white matter microstructure and providing new biomarkers. Given the rapidly increasing ... [more ▼]

Diffusion kurtosis imaging (DKI) is a promising extension of diffusion tensor imaging, giving new insights into the white matter microstructure and providing new biomarkers. Given the rapidly increasing number of studies, DKI has a potential to establish itself as a valuable tool in brain diagnostics. However, to become a routine procedure, DKI still needs to be improved in terms of robustness, reliability, and reproducibility. As it requires acquisitions at higher diffusion31 weightings, results are more affected by noise than in diffusion tensor imaging. The lack of standard procedures for post-processing, especially for noise correction, might become a significant obstacle for the use of DKI in clinical routine limiting its application. We considered two noise correction schemes accounting for the noise properties of multichannel phased-array coils, in order to improve the data quality at signal-to-noise ratio (SNR) typical for DKI. The SNR dependence of estimated DKI metrics such as mean kurtosis (MK), mean diffusivity (MD) and fractional anisotropy (FA) is investigated for these noise correction approaches in Monte Carlo simulations and in in vivo human studies. The intra-subject reproducibility is investigated in a single subject study by varying the SNR level and SNR spatial distribution. Then the impact of the noise correction on inter-subject variability is evaluated in a homogeneous sample of 25 healthy volunteers. Results show a strong impact of noise correction on the MK estimate, while the estimation of FA and MD was affected to a lesser extent. Both intra- and inter-subject SNR related variability of the MK estimate is considerably reduced after correction for the noise bias, providing more accurate and reproducible measures. In this work, we have proposed a straightforward method that improves accuracy of DKI metrics. This should contribute to standardization of DKI applications in clinical studies and making valuable inferences in group analysis and longitudinal studies. [less ▲]

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See detailEffet du mode de conservation d’huile de Jatropha curcas L. sur son efficacité dans la lutte contre les principaux insectes ravageurs du niébé (Vigna unguiculata (L.) Walp. au Niger
Abdoul Habou, zakari; Toudou, Adam; Haubruge, Eric ULg et al

in Tropicultura (in press)

Jatropha curcas oil has an insecticidal activity harnessed by the farmers in Niger. In this study, we compared the insecticidal activity of two batches of oil conserved during 70 days, one exposed to ... [more ▼]

Jatropha curcas oil has an insecticidal activity harnessed by the farmers in Niger. In this study, we compared the insecticidal activity of two batches of oil conserved during 70 days, one exposed to light and the other kept in the dark. The insecticidal efficacy was evaluated in a field with three concentrations (5, 10 and 15%) trial on the main pests of Cowpea (Vigna unguiculata (L.) Walp) and in a laboratory test on Megalurothrips sjostedti Trybon (Thysanoptera: Thripidae) with different concentrations of crude oil (50; 100; 150 and 200 µl). No difference in insecticidal effect was found between the two modes of oil conservation, both in the laboratory and in the field. In the field, regardless of the mode of conservation, the concentrations of 10% of J. curcas oil enables a reduction of over than 80% of thrips, aphids, and bugs compared to the control. Its increased seeds yield more than 50%. The concentration of 15% gives an insecticidal effect comparable to that of the reference treatment (deltaméthrine) but induces phytotoxicity symptoms on the leaves of Cowpea. [less ▲]

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See detailPérils de la copie : les cas de l’Estoire del Saint Graal, du Merlin et de la Suite Vulgate
Combes, Annie ULg

in Cahiers de Civilisation Médiévale (in press)

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See detailOn the asymptotic standard error of a class of robust estimators of ability in dichotomous item response models
Magis, David ULg

in British Journal of Mathematical & Statistical Psychology (in press)

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods ... [more ▼]

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods were introduced to lessen the impact of such aberrant responses onto the estimation process. The computation of asymptotic (i.e., large sample) standard errors (ASE) for these robust estimators, however, has not been fully considered yet. This paper focuses on a broad class of robust ability estimators, defined by an appropriate selection of the weight function and the residual measure, for which the ASE is derived from the theory of estimating equations. The maximum likelihood (ML) and the robust estimators, together with their estimated ASE, are then compared through a simulation study. It is concluded that both the estimators and their ASE perform similarly in absence of response disturbances, while the robust estimator and its estimated ASE are less biased and outperform their ML counterparts in presence of response disturbances with large impact on the item response process. [less ▲]

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See detailAlgebrability and nowhere Gevrey differentiability
Bastin, Françoise ULg; Conejero, J. Alberto; Esser, Céline ULg et al

in Israel Journal of Mathematics (in press)

We show that there exist c-generated algebras (and dense in C^infty([0,1])) every nonzero element of which is a nowhere Gevrey diff erentiable function. This leads to results of dense algebrability (and ... [more ▼]

We show that there exist c-generated algebras (and dense in C^infty([0,1])) every nonzero element of which is a nowhere Gevrey diff erentiable function. This leads to results of dense algebrability (and, therefore, lineability) of functions enjoying this property. In the process of proving these results we also provide a new construction of nowhere Gevrey di fferentiable functions. [less ▲]

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See detailIsland floras are not necessarily more species-poor than continental ones.
Patiño, J.; Solymos, P.; Carine, M.A. et al

in Journal of Biogeography (in press)

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See detailSens et signification dans l'esthétique de Mallarmé
Durand, Pascal ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (in press), 5

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See detailEvaluation of the impact of 6-month training by whole body vibration on the risk of falls among nursing home residents, observed over a 12-month period: a single blind, randomized controlled trial.
Buckinx, Fanny ULg; Beaudart, Charlotte ULg; Maquet, Didier ULg et al

in Aging Clinical & Experimental Research (in press)

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement ... [more ▼]

BACKGROUND: We have previously shown that short sessions of whole body vibration (WBV) were not able to significantly improve fall risk among nursing home residents but some trends towards an improvement of motor capacity were observed. OBJECTIVE: The objective of the present study was to evaluate the impact of 6-month training by WBV on functional and motor abilities among nursing home residents observed over a 12-month period. METHODS: Patients were randomized into two groups: the WBV group which received three training sessions every week composed of five series of 15 s of vibration at 30 Hz intensity for a period of 6 months and a control group with normal daily life. The impact of this training on the risk of falls was assessed blindly after 6 and 12 months by the Tinetti Test, the "Timed Up and Go" test and a quantitative evaluation of a 10-s walk performed with a tri-axial accelerometer. The occurrence of falls was also observed. RESULTS: 62 elderly healthy volunteers, (47 women and 15 men, mean age 83.2 +/- 7.9 years) were included in this study. There was no significant difference between the two groups regarding the Tinetti test (p = 0.75), the "Timed Up and Go" test (p = 0.19) and the Locometrix(R) test, except for the step length, measured by dual task (p < 0.01). No significant inter-group difference in the frequency of falls was observed during the 12 months of research. A total of 42 falls were recorded during the first 6 months of experimentation: 24 falls in the treated group and 18 in the control group (p = 0.60). During the next 6 months, 19 falls occurred: 8 falls in the treated group and 11 in the control group (p = 0.52). CONCLUSION: This study failed to establish the effectiveness of low doses of WBV, under the conditions used in our study, on functional and motor abilities of institutionalized elderly patients. However, given the positive results of other studies, further investigations, with modified therapeutic protocols, seem necessary to clarify the effects of WBV in the elderly. [less ▲]

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See detailComparative biogeochemistry-ecosystem-human interactions on dynamic continental margins
Levin, Lisa A.; Liu, Kon-Kee; Kay-Christian, Emeis et al

in Journal of Marine Systems (in press)

The ocean’s continental margins face strong and rapid change, forced by a combination of direct human activity, anthropogenic CO2-induced climate change, and natural variability. Stimulated by discussions ... [more ▼]

The ocean’s continental margins face strong and rapid change, forced by a combination of direct human activity, anthropogenic CO2-induced climate change, and natural variability. Stimulated by discussions in Goa, India at the IMBER IMBIZO III, we (1) provide an overview of the drivers of biogeochemical variation and change on margins, (2) compare temporal trends in hydrographic and biogeochemical data across different margins (3) review ecosystem responses to these changes, (4) highlight the importance of margin time series for detecting and attributing change and (5) examine societal responses to changing margin biogeochemistry and ecosystems. We synthesize information over a wide range of margin settings in order to identify the commonalities and distinctions among continental margin ecosystems. Key drivers of biogeochemical variation include long-term climate cycles, CO2-induced warming, acidification, and deoxygenation, as well as sea level rise, eutrophication, hydrologic and water cycle alteration, changing land use, fishing, and species invasion. Ecosystem responses are complex and impact major margin services including primary production, fisheries production, nutrient cycling, shoreline protection, chemical buffering, and biodiversity. Despite regional differences, the societal consequences of these changes are unarguably large and mandate coherent actions to reduce, mitigate and adapt to multiple stressors on continental margins. [less ▲]

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See detailEstimated daily intake and cumulative risk assessment of phthalate diesters in a Belgian general population
Dewalque, Lucas ULg; Charlier, Corinne ULg; PIRARD, Catherine ULg

in Toxicology Letters (in press)

The daily intakes (DI) were estimated in a Belgian general population for 5 phthalates, namely diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), di-iso-butyl phthalate (DiBP), butylbenzyl phthalate ... [more ▼]

The daily intakes (DI) were estimated in a Belgian general population for 5 phthalates, namely diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), di-iso-butyl phthalate (DiBP), butylbenzyl phthalate (BBzP) and di-2-ethylhexyl phthalate (DEHP), based on the urinary measurements of their corresponding metabolites. DI values ranged between <LOD and 59.65 μg/kg bw/day depending on the congener, and were globally higher for children than adults. They were compared to acceptable levels of exposure (tolerable daily intakes) to evaluate the hazard quotients (HQ), which highlight an intake above the dose considered as safe for values greater than 1. If very few of our Belgian participants exceeded this threshold for phthalates considered individually, 6.2% of the adults and 25% of the children showed an excessive hazard index (HI) which took into account the cumulative risk of adverse anti-androgenic effects. These results are of concern since these HI were based on only 3 phthalates (DEHP, DiBP and DnBP), and showed a median of 0.55 and 0.29 for children and adults respectively. The comparison with previously determined dietary intakes demonstrated that for DEHP, food intake was nearly the only route of exposure while other pathways occurred mainly for the other studied phthalates. [less ▲]

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See detailA note on weighted likelihood and Jeffreys modal estimation of proficiency levels in polytomous item response models
Magis, David ULg

in Psychometrika (in press)

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this ... [more ▼]

Warm (1989) established the equivalence between the so-called Jeffreys modal and the weighted likelihood estimators of proficiency level with some dichotomous item response models. The purpose of this note is to extend this result to polytomous item response models. First, a general condition is derived to ensure the perfect equivalence between these two estimators. Second, it is shown that this condition is fulfilled by two broad classes of polytomous models including, among others, the partial credit, rating scale, graded response and nominal response models. [less ▲]

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See detailLevallois et Gravettien
Otte, Marcel ULg; Noiret, Pierre ULg

in Praehistoria (in press)

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein ... [more ▼]

Par opposition à ceux de l’Aurignacien, les ensembles lithiques gravettiens procèdent selon une méthode rappelant le Levallois quant à la préparation des supports. Mais les variations observables au sein du Gravettien touchent autant les processus de symbolisation dans l’art et les sépultures. Elles affectent différents substrats eurasiatiques, plutôt septentrionaux, comme mis en réserve dès les Néandertaliens. [less ▲]

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See detailAn enhanced version of a bone remodelling model based on the continuum damage mechanics theory.
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg

in Computer Methods in Biomechanics & Biomedical Engineering (in press)

The purpose of this work is to propose an enhancement of Doblaré and García's internal bone remodelling model based on the continuum damage mechanics theory. In their paper, they stated that the evolution ... [more ▼]

The purpose of this work is to propose an enhancement of Doblaré and García's internal bone remodelling model based on the continuum damage mechanics theory. In their paper, they stated that the evolution of the internal variables of the bone microstructure, and its incidence on the modification of the elastic constitutive parameters, may be formulated following the principles of Continuum Damage Mechanics, although no actual damage was considered. The resorption and apposition criteria (similar to the damage criterion) were expressed in terms of a mechanical stimulus. However, the resorption criterion is lacking a dimensional consistency with the remodelling rate. We here propose an enhancement to this resorption criterion, insuring the dimensional consistency while retaining the physical properties of the original remodelling model. We then analyse the change in the resorption criterion hypersurface in the stress space for a 2D analysis. We finally apply the new formulation to analyse the structural evolution of a 2D femur. This analysis gives results consistent with the original model but with a faster and more stable convergence rate. [less ▲]

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See detailThe Sceptical President: Václav Klaus' Influence on Czech Public Opinion on Climate Change
De Pryck, Kari; Gemenne, François ULg

in Climatic Change (in press)

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See detailObservations sur l'évolution du coût du Bonus Logement pour la Wallonie
Xhignesse, Guillaume ULg

in Revue de Fiscalité Régionale et Locale (in press)

En 2011, les dépenses fiscales relatives à l'acquisition de l'habitation propre atteignaient 1.941,83 milllions d'euros dans le budget fédéral belge, soit 0,53% du PIB national. Dès l'entrée en vigueur de ... [more ▼]

En 2011, les dépenses fiscales relatives à l'acquisition de l'habitation propre atteignaient 1.941,83 milllions d'euros dans le budget fédéral belge, soit 0,53% du PIB national. Dès l'entrée en vigueur de la sixième réforme de l'Etat, ces dépenses seront à charge des budgets régionaux. Au vu des montants importants qui sont en jeu, il est nécessaire d'amorcer une réflexion sur ces aides à l'acquisition. Cette réflexion doit avant tout porter sur l'adéquation de ces aides avec les enjeux actuels et futurs en matière de logement, ainsi que sur les effets réels de ces mécanismes. Si, malgré ces interrogations, les décideurs politiques choisissent de maintenir le système en l'état, il est utile d'estimer quels seront les coûts pour les années à venir. Cette contribution se concentre sur ce dernier aspect du problème, dans le cas de la Wallonie. [less ▲]

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See detailLe Mur et le masque. À propos de Banksy.
Saint-Amand, Denis ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

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See detailBrain metabolic dysfunction in Capgras delusion during Alzheimer’s disease: a positron emission tomography study
Jedidi, Haroun ULg; Daury, Noémy; Rémi, Capa et al

in American Journal of Alzheimer's Disease & Other Dementias (in press)

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since ... [more ▼]

Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since little is known regarding the neural correlates of Capgras syndrome, the cerebral metabolic pattern of a patient with probable Alzheimer’s disease (AD) and Capgras syndrome was compared with those of 24 healthy elderly subjects and 26 AD patients without delusional syndrome. Compared to the healthy and AD groups, the patient had significant hypometabolism in frontal and posterior midline structures. In light of current neural models of face perception, our patient’s Capgras syndrome may be related to impaired recognition of a familiar face, subserved by the posterior cingulate/precuneus cortex, and impaired reflection about personally relevant knowledge related to a face, subserved by the dorsomedial prefrontal cortex. [less ▲]

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See detailSinging ability is rooted in vocal-motor control of pitch
Hutchins, Sean; Larrouy, Pauline ULg; Peretz, Isabelle

in Attention, Perception & Psychophysics (in press)

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and ... [more ▼]

The inability to vocally match a pitch can be caused by poor pitch perception or by poor vocal-motor control. Although previous studies have tried to examine the relationship between pitch perception and vocal production, they have failed to control for the timbre of the target to be matched. In the present study, we compare pitch matching accuracy with an unfamiliar instrument (the slider) and with the voice, designed such that the slider plays back recordings of the participant’s own voice. We also measured pitch accuracy in singing a familiar melody (“Happy Birthday”) to assess the relationship between single pitch matching tasks and melodic singing. Our results showed that participants (all nonmusicians) were significantly better at matching recordings of their own voices with the slider than with their voice, indicating that vocal-motor control is an important limiting factor on singing ability. We also found significant correlations between the ability to sing a melody in tune and vocal pitch matching, but not instrumental pitch matching. Better melodic singers also tended to have higher quality voices (as measured by acoustic variables). These results provide important evidence about the ultimate causes of poor singing ability, and demonstrate that single pitch matching tasks can be useful in measuring general singing abilities. [less ▲]

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See detailApproche par compétences et évaluation à large échelle : deux logiques incompatibles ?
Dierendonck, Christophe; Fagnant, Annick ULg

in Mesure et Evaluation en Education [=MEE] (in press), 37(1), 43-82

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See detailModelling the distribution of key tree species used by lion tamarins in the Brazilian Atlantic forest under a scenario of future climate change
Raghunathan, N.; François, Louis ULg; Huynen, Marie-Claude ULg et al

in Regional Environmental Change (in press)

We used three IPCC climate change scenarios (A1B, A2 and B1) in a dynamic vegetation model (CARAIB), to determine the potential future distribution of 75 tree species used by two endemic primate species ... [more ▼]

We used three IPCC climate change scenarios (A1B, A2 and B1) in a dynamic vegetation model (CARAIB), to determine the potential future distribution of 75 tree species used by two endemic primate species from the Brazilian Atlantic Forest (BAF). Habitat conservation is a vital part of strategies to protect endangered species, and this is a new approach to understanding how key plant species needed for survival of golden lion tamarins (Leontopithecus rosalia) and golden-headed lion tamarins (L. chrysomelas) might be affected by climate change and what changes to their distribution are likely. The model accurately predicted the current distribution of BAF vegetation types, for 66 % of the individual tree species with 70 % agreement obtained for presence. In the simulation experiments for the future, 72 out of 75 tree species maintained more than 95 % of their original distribution and all species showed a range expansion. At the biome level, we note a substantial decrease in the sub-tropical forest area. There is some fragmentation of the savannah, which is encroached mostly by tropical seasonal forest. Where the current distribution shows a large sub-tropical forest biome, it has been replaced or encroached by tropical rainforest. The results suggested that the trees may benefit from an increase in temperature, if and only if soil water availability is not altered significantly, as was the case with climate simulations that were used. However, these results must be coupled with other information to maximise usefulness to conservation since BAF is already highly fragmented and subject to high anthropic pressure. © 2014 Springer-Verlag Berlin Heidelberg. [less ▲]

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See detailMartin Heidegger, Extrait du dernier cours de Marbourg
Pieron, Julien ULg

in Philosophie (in press)

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See detailA European survey on attitudes towards pain and end-of-life issues in locked-in syndrome
Demertzi, Athina ULg; Jox, Ralf J; Racine, Eric et al

in Brain Injury (in press)

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]

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See detailVascular calcification: from pathophysiology to biomarkers
EVRARD, Séverine ULg; DELANAYE, Pierre ULg; Kamel, S et al

in Clinica Chimica Acta (in press)

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have ... [more ▼]

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have highlightedmore and more physiopathological mechanisms and signaling pathways that underlie VC. Several conditions such as diabetes, dyslipidemia and renal diseases are undoubtedly identified as predisposing factors. But even if the process is better understood,many questions still remain unanswered. This reviewbriefly develops the various theories that attempt to explain mineralization genesis. Nonetheless, the main purpose of the article is to provide a profile of the various existing biomarkers of VC. Indeed, in the past years, a lot of inhibitors and promoters, which form a dense and interconnected network, were identified. Given importance to assess and control mineralization process, a focusing on accumulated knowledge of each marker seemed to be necessary. Therefore, we tried to define their respective role in the physiopathology and how they can contribute to calcification risk assessment. Among these, Klotho/fibroblast growth factor-23, fetuin-A, Matrix Gla protein, Bone morphogenetic protein-2, osteoprotegerin, osteopontin, osteonectin, osteocalcin, pyrophosphate and sclerostin are specifically discussed. [less ▲]

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See detailFungal biofilm reactor improves the productivity of hydrophobin HFBII
Khalesi, Mohammadreza; Zune, Quentin ULg; Telek, Samuel ULg et al

in Biochemical Engineering Journal (in press)

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at ... [more ▼]

Production and purification of hydrophobin HFBII has recently been the subject of intensive research, but the yield of production needs to be further improved for a generic use of this molecule at industrial scale. In a first step, the influence of different carbon sources on the growth of Trichoderma reesei and the production of HFBII was investigated. The optimum productivity was obtained by using 40 g/L lactose. Carbon starvation and excretion of extracellular enzyme were determined as two main conditions for the production of HFBII. In the second phase, and according to the physiological mechanisms observed during the screening phase, a bioreactor set up has been designed and two modes of cultures have been investigated, i.e. the classical submerged fermentation and a fungal biofilm reactor. In this last set-up, the broth is continuously recirculated on a metal packing exhibiting a high specific surface. In this case, the fungal biomass was mainly attached to the metal packing, leading to a simplification of downstream processing scheme. More importantly, the HFBII concentration increased up to 48.6 ± 6.2 mg/L which was 1.8 times higher in this reactor configuration and faster than the submerged culture. X-ray tomography analysis shows that the biofilm overgrowth occurs when successive cultures are performed on the same packing. However, this phenomenon has no significant influence on the yield of HFBII, suggesting that this process could be operated in continuous mode. Protein hydrolysis during stationary phase was observed by MALDI-TOF analysis according to the removal of the last amino acid from the structure of HFBII after 48 h from the beginning of fermentation in biofilm reactor. Hopefully this modification does not lead to alternation of the main physicochemical properties of HFBII. [less ▲]

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See detailInfluence of Homogenization Treatment on Physicochemical 4 Properties and Enzymatic Hydrolysis Rate of Pure 5 Cellulose Fibers
Jacquet, Nicolas ULg; Vanderghem, Caroline ULg; Danthine, Sabine ULg et al

in Applied Biochemistry and Biotechnology (in press)

The aim of this study is to compare the effect of different homogenization treat- 12 ments on the physicochemical properties and the hydrolysis rate of a pure bleached 13 cellulose. Results obtained show ... [more ▼]

The aim of this study is to compare the effect of different homogenization treat- 12 ments on the physicochemical properties and the hydrolysis rate of a pure bleached 13 cellulose. Results obtained show that homogenization treatments improve the enzymatic 14 hydrolysis rate of the cellulose fibers by 25 to 100 %, depending of the homogenization 15 treatment applied. Characterization of the samples showed also that homogenization had an 16 impact on some physicochemical properties of the cellulose. For moderate treatment inten- 17 sities (pressure below 500 b and degree of homogenization below 25), an increase of water 18 retention values (WRV) that correlated to the increase of the hydrolysis rate was highlighted. 19 Result also showed that the overall crystallinity of the cellulose properties appeared not to be 20 impacted by the homogenization treatment. For higher treatment intensities, homogenized 21 cellulose samples developed a stable tridimentional network that contributes to decrease 22 cellulase mobility and slowdown the hydrolysis process. [less ▲]

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See detailMultiscale variability of amphipod assemblages in Posidonia oceanica meadows
Sturaro, Nicolas ULg; Lepoint, Gilles ULg; Vermeulen, Simon et al

in Journal of Sea Research (in press)

The study of spatial patterns is of ecological importance in order to understand the causes of the distribution and abundance of organisms, and it also provides valuable basis for management and ... [more ▼]

The study of spatial patterns is of ecological importance in order to understand the causes of the distribution and abundance of organisms, and it also provides valuable basis for management and conservation. Amphipod crustaceans are key organisms in seagrass ecosystems. However, little attention has been paid to the spatial scales at which amphipod assemblages may vary. We examined variability patterns of amphipod populations inhabiting Posidonia oceanica meadows, over spatial scales spanning four orders of magnitude (1 to 1000 metres) and for two consecutive years. This study reports the scales that contributed most to spatial variation of amphipod assemblages and explores the potential processes of the observed patterns, with particular emphasis on habitat features. The number of species, the diversity and the density of some species, exhibited high variation across years. Most species showed the highest spatial variation in density and biomass at small scales (~1 and 10 m). Based on density data, the structure of amphipod assemblages did not differ at any scales investigated. The patchiness that occurred at small scales may have been only weakly related to habitat features. Instead, we postulated that behavioural processes of amphipods were likely good explanatory factors. Although, the small scale spatial variability can be an important feature of amphipod assemblages in P. oceanica meadows, many patterns probably remained undetected as they may occur at scales smaller than those investigated. [less ▲]

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See detailHydroxymethylfurfural: a possible emergent cause of honey bee mortality?
Zirbes, Lara ULg; Nguyen, Bach Kim ULg; de Graaf, DC et al

in Journal of Agricultural and Food Chemistry (in press)

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See detailInteraction between dietary protein content and the source of carbohydrates along the gastrointestinal tract of weaned piglets.
Pieper, Robert; Boudry, Christelle ULg; Bindelle, Jérôme ULg et al

in Archives of Animal Nutrition (in press)

Although fermentable carbohydrates (CHO) can reduce metabolites derived from dietary protein fermentation in the intestine of pigs, the interaction between site of fermentation and substrate availability ... [more ▼]

Although fermentable carbohydrates (CHO) can reduce metabolites derived from dietary protein fermentation in the intestine of pigs, the interaction between site of fermentation and substrate availability along the gut is still unclear. The current study aimed at determining the impact of two different sources of carbohydrates in diets with low or very high protein content on microbial metabolite profiles along the gastrointestinal tract of piglets. Thirty-six piglets (n = 6 per group) were fed diets high (26%, HP) or low (18%, LP) in dietary protein and with or without two different sources of carbohydrates (12% sugar beet pulp, SBP, or 8% lignocellulose, LNC) in a 2 × 3 factorial design. After 3 weeks, contents from stomach, jejunum, ileum, caecum, proximal and distal colon were taken and analysed for major bacterial metabolites (D-lactate, L-lactate, short chain fatty acids, ammonia, amines, phenols and indols). Results indicate considerable fermentation of CHO and protein already in the stomach. HP diets increased the formation of ammonia, amines, phenolic and indolic compounds throughout the different parts of the intestine with most pronounced effects in the distal colon. Dietary SBP inclusion in LP diets favoured the formation of cadaverine in the proximal parts of the intestine. SBP mainly increased CHO-derived metabolites such as SCFA and lactate and decreased protein-derived metabolites in the large intestine. Based on metabolite profiles, LNC was partly fermented in the distal large intestine and reduced mainly phenols, indols and cadaverine, but not ammonia. Multivariate analysis confirmed more diet-specific metabolite patterns in the stomach, whereas the CHO addition was the main determinant in the caecum and proximal colon. The protein level mainly influenced the metabolite patterns in the distal colon. The results confirm the importance of CHO source to influence the formation of metabolites derived from protein fermentation along the intestinal tract of the pig. [less ▲]

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See detailLa maladie de Lyme entre cadrage infectieux, vectoriel et zoonotique : vers une écologisation des problèmes sanitaires ?
Massart, Clémence ULg

in VertigO : la Revue Electronique en Sciences de l'Environnement (in press)

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ... [more ▼]

Cet article est consacré à la qualification de la maladie de Lyme en France. Principale pathologie vectorielle de l’hémisphère nord, la maladie de Lyme est transmise par une tique du genre Ixodes (Ixodes ricinus en Europe ; Ixodes persulcatus en Asie ; Ixodes scapularis aux États-Unis et au Canada). Les médecins et les malades ont d’abord développé un cadrage infectieux, ancré dans la santé humaine, réservé à Lyme et soumis à une vive controverse. Progressivement, un second cadrage vectoriel s’est structuré autour des entomologistes médicaux puis des écologues, généralement étrangers à la problématique des maladies humaines. Axé sur le vecteur, ce cadrage englobe les autres maladies transmises par Ixodes ricinus en Europe qui, durant les 30 dernières années, n’ont cessé d’être découvertes : bartonnelles, babésioses, tularémie, encéphalite à tiques, etc. Combinée à ces nouvelles pathologies, la notoriété de Lyme a finalement contribué à ouvrir la catégorie « transmission vectorielle » – traditionnellement associée aux moustiques des pays tropicaux – aux tiques et aux maladies de l’hémisphère nord qu’elles véhiculent. Un troisième cadrage axé sur les réservoirs et qualifié de zoonotique commence enfin à se dessiner. Il faut reconnaître dans cette juxtaposition des cadrages – infectieux, vectoriel et zoonotique – une forme d’écologisation des problèmes sanitaires. [less ▲]

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See detailUne approche basée objet combinée avec les classifieurs avancés (SVM, RF, Extra Trees) pour la détection des changements du bâti
El Mansouri, Loubna ULg

in Rig (in press)

Cet article expose le développement d’une méthodologie automatique pour la détection des changements du bâti en vue d'une mise à jour semi automatique des cartes urbaines. L'approche est basée sur la ... [more ▼]

Cet article expose le développement d’une méthodologie automatique pour la détection des changements du bâti en vue d'une mise à jour semi automatique des cartes urbaines. L'approche est basée sur la comparaison entre une carte existante et une image à très haute résolution spatiale (THRS) récente. Elle s'enchaine sur 4 étapes. D'abord l'image est segmentée pour produire des primitives. Ces dernières sont caractérisées par 4 catégories d'attributs. Des classifieurs avancés par apprentissage supervisé (CAAS) ont été utilisés dans l'étape de la classification. Le paramétrage optimal de ces classifieurs est obtenu automatiquement par validation croisée en se référant au meilleur taux d'erreur. La prédiction finale des objets est déduite par un combineur de multiples classifieurs (CMC) conçu à partir des 3 meilleurs CAAS. Enfin, une étape de détection des changements permet d'identifier les primitives qui représentent les changements du bâti. Les données utilisées concernent la ville de Rabat (Maroc). Une image QuickBird a été utilisée avec un plan existant à l'échelle 1:10,000. Indépendamment de la qualité de la forme des bâtiments détectés, la méthode offre des meilleurs taux en exhaustivité (91.7%) et en exactitude (81.5%). [less ▲]

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See detailDiagnostic des viroses et séquençage haut-débit : vers un changement de paradigme ?
Massart, Sébastien ULg; Olmos, Antonio; Jijakli, Haissam ULg et al

in Virologie (in press), 5

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See detailJatropha curcas L. (Euphorbiaceae): Insectes ravageurs et propriétés biocides
Abdoul Habou, Zakari; Toudou, Adam; Haubruge, Eric ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Jatropha curcas, ou Pourghère, est un arbuste de la famille des Euphorbiacées, largement répandu dans les pays tropicaux. Ses graines sont riches d'une huile pouvant servir de biocarburant dans les ... [more ▼]

Jatropha curcas, ou Pourghère, est un arbuste de la famille des Euphorbiacées, largement répandu dans les pays tropicaux. Ses graines sont riches d'une huile pouvant servir de biocarburant dans les moteurs diesels modifiés. La plante est attaquée par divers insectes ravageurs appartenant principalement aux ordres des Hétéroptères, Coléoptères et Orthoptères. Ils provoquent des dégâts sur les fruits, les inflorescences et les feuilles. Les ravageurs les plus fréquemment observés sur J. curcas sont des punaises du genre Pachycoris (Hétéroptère : Scutelleridae), qui sont largement répandues au Mexique, en Australie, aux États-Unis, au Brésil et au Nicaragua. Ces punaises causent des dégâts importants sur les fruits et provoquent la malformation des graines, et avec elle une réduction de la teneur en huile. Même si les arbustes de Jatropha sont victime d'infestations d'insectes, plusieurs études démontrent l'effet insecticide de son huile contre des ravageurs importants tels que Busseola fusca (Fuller) (Lépidoptère : Noctuidae), Sesamia calamistis Hampson (Lépidoptère : Noctuidae), Aphis gossypii Glover (Homoptère: Aphididae) et Callosobruchus chinensis L. (Coléoptère : Bruchidae). Dans ce document, nous présentons dans une première partie les principaux insectes ravageurs de J. curcas et dans une seconde section les effets insecticides démontrés de son huile. [less ▲]

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