Y a-t-il encore une place pour la double inhibition du système rénine-angiotensine en 2012?Krzesinski, Jean-Marie ; Scheen, André ![]() in Revue Médicale Suisse (2012), 8(351), 1598-1603 The blockade of the renin-angiotensin system (RAS) improves the prognosis of patients with complications related to diabetes, hypertension or, in general, atherosclerosis. Several observational studies ... [more ▼] The blockade of the renin-angiotensin system (RAS) improves the prognosis of patients with complications related to diabetes, hypertension or, in general, atherosclerosis. Several observational studies have suggested the use of a dual blockade of the RAS to benefit from a better cardiorenal protection. However, recent randomized controlled studies failed to demonstrate that a dual blockade exert a better protection than single blockade, but showed a higher risk for renal complications and hyperkalemia. To decrease the residual risk, other opportunities may be recommended such as reinforcement of low salt diet, use of supraphysiological dose of a monotherapy inhibiting the RAS (perhaps prescribed at the evening) or addition of an aldosterone antagonist. However, all these approaches, as dual therapy, may also increase the risk of hypotension and renal insufficiency and thus require to be used under strict medical supervision. [less ▲] Detailed reference viewed: 39 (13 ULg) Y a-t-il managérialisation de l'intervention sociale ?Vrancken, Didier ![]() Conference given outside the academic context (2012) Que ce soit au sein des entreprises privées, publiques ou au sein des associations, la managérialisation devient aujourd'hui un phénomène qui traverse également l'intervention sociale et engendre nombre ... [more ▼] Que ce soit au sein des entreprises privées, publiques ou au sein des associations, la managérialisation devient aujourd'hui un phénomène qui traverse également l'intervention sociale et engendre nombre de contradictions pour les "travailleurs du social". [less ▲] Detailed reference viewed: 34 (3 ULg) Y a-t-il un courant des Lumières en Hongrie, en Europe centrale et orientale?Droixhe, Daniel ![]() in Acta Litteraria Academiae Scientiarum Hungaricae (1972), 14 Detailed reference viewed: 39 (10 ULg) "Y a-t-il un discours universitaire dans la salle (de cours)?"Defays, Jean-Marc ![]() Conference (2007) Detailed reference viewed: 18 (2 ULg) Y a-t-il une censure dans l’information ?Geuens, Geoffrey ![]() Conference given outside the academic context (2001) Detailed reference viewed: 9 (1 ULg) Y a-t-il une filiation entre la structure des fiches de malades dans les Épidémies hippocratiques et celle des rapports médicaux grecs d’Égypte (Ier-IVe siècles) conservés sur papyrus ?Ricciardetto, Antonio ![]() Conference (2013, May 10) Detailed reference viewed: 16 (2 ULg) Y a-t-il une place d'emblée pour une bithérapie faiblement dosée dans le traitement de l'hypertension artérielle essentielle?Krzesinski, Jean-Marie ; Rorive, Marcelle ![]() in Médecine et Hygiène (2003), 61 If the treatment of hypertension is very useful to decrease the cardiovascular risk, the way to get the normalisation of high blood pressure is difficult in spite of many families of antihypertensive ... [more ▼] If the treatment of hypertension is very useful to decrease the cardiovascular risk, the way to get the normalisation of high blood pressure is difficult in spite of many families of antihypertensive agents with different mechanisms of action. To reach such objective, association of different drugs are most often required. But, the european guidelines for the management of hypertension have just been released and proposed the possibility to begin very-low-dose combination therapy first-line. These associations offer immediate higher efficacy, excellent tolerance and low cost. [less ▲] Detailed reference viewed: 14 (1 ULg) y a-t-il une place pour la radiothérapie en fin de vie ?BARTHELEMY, Nicole ; JANSEN, Nicolas ; GENNIGENS, Christine et alin Revue Médicale de Liège (2012), 67(3), 128132 Près de 50 % des patients atteints d’un cancer bénéficient, à un moment de leur trajet de soins, d’une irradiation. Celle-ci peut être administrée avec une intention curative ou palliative, en fonction de ... [more ▼] Près de 50 % des patients atteints d’un cancer bénéficient, à un moment de leur trajet de soins, d’une irradiation. Celle-ci peut être administrée avec une intention curative ou palliative, en fonction de l’extension de la maladie, de l’état général du patient et de sa volonté. Le but d’une irradiation palliative, sera de contrôler localement la tumeur ou la métastase et, donc, de ralentir l’évolution du cancer. La radiothérapie peut également être utile pour supprimer un symptôme et, ainsi, être un des traitements de confort en fin de vie. La dose totale, la dose par fraction ainsi que la technique d’irradiation sont adaptées à l’intention du traitement. Cet article passe en revue les principales indications d’irradiation en fin de vie. [less ▲] Detailed reference viewed: 25 (1 ULg) Y a-t-il une place pour les β-bloquants dans les maladies pulmonaires obstructives ?; FRUSCH, Nicolas ; DUYSINX, Bernard et alin Revue Médicale de Liège (2011), 66(12), 619-623 Detailed reference viewed: 15 (3 ULg) Y a-t-il une ritualité initiatique et des rites de passage pour les adolescents de nos sociétés occidentales contemporaines?Stassart, Martine ![]() in Observatoire : Revue d'Action Sociale & Médico-Sociale (2004), 42 All societies are concerned on a highest point with getting over from childhood to adulthood. The socalled primitive people solved that problem through ritual initiation which is identically organized by ... [more ▼] All societies are concerned on a highest point with getting over from childhood to adulthood. The socalled primitive people solved that problem through ritual initiation which is identically organized by the various "primitive" cultures. Is there an equivalent of that process in the modern western culture? [less ▲] Detailed reference viewed: 87 (6 ULg) Y a-t-ildes nerfs spéciaux pour la douleur?Fredericq, Léon ![]() in Revue Scientifique (1896) Detailed reference viewed: 2 (0 ULg) Y être, c’est en être : le Groupe Bilderberg et la Commission trilatéraleGeuens, Geoffrey ![]() Article for general public (2008) Detailed reference viewed: 81 (1 ULg) Y'a du projet dans l'air; ; Hindryckx, Marie-Noëlle ![]() Report (1997) Detailed reference viewed: 9 (0 ULg) Y'a plus d'poissons... Y'a plus d'reptilesHindryckx, Marie-Noëlle ![]() in TRACeS de ChanGements (2009), 193 Detailed reference viewed: 61 (12 ULg) Y'a-t-il des missionnaires congolais en BelgiqueDemart, Sarah ![]() Conference (2010) Detailed reference viewed: 14 (0 ULg) Yaken detachment fold, Southern Tianshan, ChinaHubert, Aurelia ; ; et alin American Association of Petroleum Geologists Atlas (2004) Yakeng anticline illustrates the importance of working in the thickness domain when interpreting detachment folds. Measure- ments in the thickness domain show that Yakeng has 1.2 km shorten- ing above a ... [more ▼] Yakeng anticline illustrates the importance of working in the thickness domain when interpreting detachment folds. Measure- ments in the thickness domain show that Yakeng has 1.2 km shorten- ing above a basal two levels of major detachment, basal diapirism, basement folding, and a 2.4-km-thick growth sequence. [less ▲] Detailed reference viewed: 24 (0 ULg) Yakubovich’s Oscillatority of Circadian Oscillations ModelsEfimov, Denis ; in Mathematical Biosciences (2008), 216 The testing procedure of Yakubovich’s oscillatority property is presented. The procedure is applied for two models of circadian oscillations [10], [11]. Analytical conditions of these models oscillatority ... [more ▼] The testing procedure of Yakubovich’s oscillatority property is presented. The procedure is applied for two models of circadian oscillations [10], [11]. Analytical conditions of these models oscillatority are established and bounds on oscillation amplitude are calculated. [less ▲] Detailed reference viewed: 10 (0 ULg) YB-1 represses AP1-dependent gene transactivation and interacts with an AP-1 DNA sequence.; Twizere, Jean-Claude ; in Biochemical Journal (2005), 388(Pt 3), 921-8 Involvement of the AP-1 (activator protein-1) transcription factor has been demonstrated previously in the regulation of cell proliferation and cell-cycle progression, in the control of cell migration ... [more ▼] Involvement of the AP-1 (activator protein-1) transcription factor has been demonstrated previously in the regulation of cell proliferation and cell-cycle progression, in the control of cell migration, invasion and metastasis, and in signal transduction, stress responsiveness, DNA replication and DNA repair. YB-1 (Y-box-binding protein-1) has also been implicated in many of these processes. However, the mechanism by which YB-1 mediates these processes is poorly understood. In the present study, we report that overexpression of a transfected gene encoding YB-1 in human HeLa cervical carcinoma cells significantly represses the transactivation of a minimal AP-1 reporter construct in response to the tumour promoter PMA. YB-1 also represses mRNA expression and PMA-induced promoter transactivation of the endogenous AP-1 target gene encoding matrix metalloproteinase-12 (metalloelastase). YB-1 transrepression of both the minimal and matrix metalloproteinase-12 promoter reporter constructs is dependent on the AP-1 sequence. To identify new nuclear proteins that bind specifically to the AP-1 DNA-binding site, we devised a DNA-affinity-chromatography-based assay termed NAPSTER (nucleotide-affinity preincubation specificity test of recognition) and discovered a 49 kDa protein from human cancer cells that binds in a sequence-specific manner to the AP-1 DNA sequence. By tandem MS fragmentation sequencing analyses we determined that p49 is a YB-1. Immunoblotting of the NAPSTER-purified p49 protein using anti-YB-1 antibodies confirmed YB-1 binding to the AP-1 DNA sequence, as did gel mobility-supershift assays using YB-1 antibodies. This is the first report of YB-1 transrepression and interaction at the AP-1 DNA-binding site. [less ▲] Detailed reference viewed: 56 (1 ULg) YBa2Cu3O(7-delta) thick films on Ag prepared by the electrophoretic deposition technique; ; Fagnard, Jean-François et alin Journal of Physics: Conference Series [=JPCS] (2006), 43 YBa2Cu3O7-δ thick films have been deposited onto Ag substrates by the Electrophoretic Deposition (EPD) technique. Different microstructures and electrical behaviours were observed depending on the ... [more ▼] YBa2Cu3O7-δ thick films have been deposited onto Ag substrates by the Electrophoretic Deposition (EPD) technique. Different microstructures and electrical behaviours were observed depending on the starting powder. Coatings prepared from commercial powder displayed significant porosity and the superconducting transition width was found to be magnetic-field dependent. Films produced from home-made coprecipitated powder are denser but contain some secondary phases. No dependence of the resistive transition as a function of magnetic field (H ≤ 20 Oe) was observed in that case. [less ▲] Detailed reference viewed: 41 (8 ULg) YBa2Cu3O7 tapes prepared by sol-gel deposition techniques: microstructure and structural characterizationsMarguillier, David ; Cloots, Rudi ; Rulmont, André et alin Physica C: Superconductivity (2002), 372(Part 2), 715-718 We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the ... [more ▼] We report on the preparation conditions of YBa2Cu3O7 polycrystalline superconducting tapes by a sol-gel deposition technique. We present some discussion on the compatibility between the nature of the substrate, the use of a buffer layer, and the conditions used to prepare appropriate superconducting YBa2Cu3O7,, materials. We report also on the microstructural characterizations performed in order to evaluate the crystallites size, degree of orientation and connectivity. (C) 2002 Elsevier Science B.V. All rights reserved. [less ▲] Detailed reference viewed: 24 (3 ULg) |
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