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See detailp-[18F]MPPF, 5-HT1A antagonist: comparison to [3H]8-OH-DPAT with autoradiography
Plenevaux, Alain ULg; Weissmann, D.; Lemaire, Christian ULg et al

in Society for Neuroscience / Abstracts (1999)

p-MPPF 4-(2’-methoxyphenyl)-1-[2’-[N-(2’’-pyridinyl)-p-fluorobenzamido] ethyl]piperazine is the para-fluorobenzoyl analog of the highly selective 5-HT1A antagonist WAY-100635. The one step procedure used ... [more ▼]

p-MPPF 4-(2’-methoxyphenyl)-1-[2’-[N-(2’’-pyridinyl)-p-fluorobenzamido] ethyl]piperazine is the para-fluorobenzoyl analog of the highly selective 5-HT1A antagonist WAY-100635. The one step procedure used to label p-MPPF with fluorine-18 (cyclotron produced positron emitter of 110 min half-life) leads to a radiopharmaceutical compound easily prepared on a large scale. The preliminary evaluations conducted in rats and cats are good reason to consider p-[18F]MPPF as an interesting reversible radioligand to study the 5-HT1A receptor family in humans with positron emission tomography (PET). In this paper we report a careful comparison between p-[18F]MPPF and [3H]8-OH-DPAT with autoradiography and quantitative densitometry in the same animal. All experiments were conducted in Sprague Dawley male rats. For p-[18F]MMPF, the results were obtained ex-vivo after an intravenous injection of high specific activity radioligand (0.8-1.5 Ci/µmol) in vigil (no anesthesia), free moving and unstressed animals. For the purpose, permanent cannulation of the posterior vena cava were realized at least four days in advance. The [3H]8-OH-DPAT results were obtained in vitro on adjacent coronal sections to the one used for the p-[18F]MPPF autoradiography. Quantitative densitometry was employed to compare the values obtained in relevant brain structures (frontal cortex, lateral septum, hippocampus, dorsal raphe, entorhinal cortex and cerebellum). The plot of the p-[18F]MPPF values obtained for each structure against the [3H]8-OH-DPAT results displayed a significant linear correlation. These results demonstrate that from a qualitative as well as quantitative point of view, the binding of p-[18F]MPPF is totally comparable to the one of [3H]8-OH-DPAT. Supported by grants from INSERM/CGRI and FNRS Belgium. [less ▲]

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See detailp-[18F]MPPF, a fluoro analog of WAY-100635 for visualisation of 5-HT1A receptors in cat.
Le Bars, D.; Ginovart, N.; Hassoun, W. et al

in Journal of Labelled Compounds & Radiopharmaceuticals (1999), 42

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See detailLe p-[18F]MPPF: un nouveau ligand pour l'étude par TEP des récepteurs 5-HT1A
Ginovart, Nathalie; Le Bars, Didier; Lemaire, Christian ULg et al

Poster (1997, May 25)

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See detailP-doped titania xerogels as efficient UV-visible photocatalysts
Bodson, Céline ULg; Pirard, Sophie ULg; PIRARD, Arlette ULg et al

in Journal of Materials Science and Chemical Engineering (2014), 2

In the present study, sol-gel process is used to synthesize P-doped TiO2 xerogels by the cogelation method of a functionalized P alkoxide, (NH2-(CH2)2-NH-(CH2)2-P(O)-(OC2H5)2) with Ti(OC3H7)4 in either 2 ... [more ▼]

In the present study, sol-gel process is used to synthesize P-doped TiO2 xerogels by the cogelation method of a functionalized P alkoxide, (NH2-(CH2)2-NH-(CH2)2-P(O)-(OC2H5)2) with Ti(OC3H7)4 in either 2-methoxyethanol or isopropanol. The phosphorus-doping improved the thermal stability of titania and decreased the phase transformation of anatase into rutile. This modification by phosphorus shifted the absorption edge of titania to the visible region as proved by Diffuse reflectance measurements, and thus offers the possibility to produce visible light effective TiO2 photocatalyst. The excellent photocatalytic activity of P-doped TiO2 xerogels compared to pure TiO2 could be explained by its high surface area and small TiO2-anatase crystallite size. From these results, it was proved by using three different models that phosphorus intrinsically influences the photocatalytic activity. [less ▲]

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See detailp-mode Oscillations of alpha Cen A
Thoul, Anne ULg; Scuflaire, Richard ULg; Vatovez, B. et al

in Astrophysics & Space Science (2003), 284

Models of alpha Cen A & B have been computed using the masses determined by Pourbaix et al. (2002) and the data derived from the spectroscopic analysis of Neuforge and Magain (1997). The seismological ... [more ▼]

Models of alpha Cen A & B have been computed using the masses determined by Pourbaix et al. (2002) and the data derived from the spectroscopic analysis of Neuforge and Magain (1997). The seismological data obtained by Bouchy and Carrier (2001, 2002) do help improve our knowledge of the evolutionary status of the system. All the constraints are satisfied with a model which gives an age of about 6 Gyr for the binary. [less ▲]

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See detailP. Carruthers, "Pour une théorie dispositionnelle de la pensée d'ordre supérieur"
Dewalque, Arnaud ULg

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et Représentation. Controverses récentes en philosophie de l'esprit (2015)

Traduction française du célèbre chapitre de Peter Carruthers, "HOP over FOR, HOT Theory". L'auteur y soutient que les théories représentationnelles de premier ordre (Dretske, Tye, et alii) et les théories ... [more ▼]

Traduction française du célèbre chapitre de Peter Carruthers, "HOP over FOR, HOT Theory". L'auteur y soutient que les théories représentationnelles de premier ordre (Dretske, Tye, et alii) et les théories actualistes de la pensée d'ordre supérieur (e.g., Rosenthal) se heurtent à deux sérieuses difficultés: l'incapacité à rendre compte des concepts d'expérience recognitionnels et l'incapacité à expliquer pourquoi certains états sont phénoménalement conscients et d'autres non. P. Carruthers introduit et défend une théorie alternative, d'après laquelle un état mental est phénoménalement conscient si et seulement s'il est mis à la disposition d'une pensée d'ordre supérieur possible. Cette théorie est baptisée théorie dispositionnelle de la pensée d'ordre supérieur ou "théorie du double contenu". [less ▲]

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See detailP. Colon. Inv. 4781 verso: vente d'une esclave
Straus, Jean ULg

in Zeitschrift für Papyrologie und Epigraphik (1993), 98

Edition du contrat de vente d'une esclave. Papyrus grec d'Egypte. Ptolémaïs Euergétis, 3 décmebre 65

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See detailP. H. Liotta, the Graveyard of Fallen Monuments
Delville, Michel ULg

in Sentence: A Journal of Prose Poetics (2008), 7

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See detailLe P. Vindob. L 150 et les "glossaires" virgiliens
Rochette, Bruno ULg

in Chronique d'Egypte : Bulletin Périodique de la Fondation Egyptologique Reine Elisabeth (1989), 64(127-128), 231-234

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See detailLa P.E.B. expliquée
Delnoy, Michel ULg

in Delnoy, Michel; Hauglustaine, Jean-Marie; Levaux, Jean-Baptiste (Eds.) La P.E.B. expliquée (2009)

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See detailP.E.T.R.A.E. : une banque de données des inscriptions grecques et latines
Denooz, Joseph ULg

in Archéo-log (1988), 3

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See detailP.PalauRib. inv. 388 : fragment de codex de papier. IV Rois 15, 26-34 ; 18, 30-33 ; 18, 37-19, 2
Carlig, Nathan ULg

in Coptica Barcinonensia. Texts and Documents from the 5th International Seminar of Coptic Papyrology (Barceloe, 6-13 July 2014) (in press)

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See detailP.PalauRib. inv. 391 : lettre réutilisée comme exercice d’écriture
Carlig, Nathan ULg

in Coptica Barcinonensia. Texts and Documents from the 5th International Seminar of Coptic Papyrology (Barceloe, 6-13 July 2014) (in press)

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See detailP.ParisBnF inv. Suppl. gr. 1385. Un nouveau papyrus homérique
Carlig, Nathan ULg

Scientific conference (2012, February 17)

Description, édition, identification et commentaire du P.ParisBnF inv. Suppl. gr. 1385 (inédit), conservé à la Bibliothèque nationale de France et contenant un passage de l'Iliade d'Homère, réunion avec ... [more ▼]

Description, édition, identification et commentaire du P.ParisBnF inv. Suppl. gr. 1385 (inédit), conservé à la Bibliothèque nationale de France et contenant un passage de l'Iliade d'Homère, réunion avec un autre fragment de papyrus provenant de la même entité bibliologique et présentation des outils de la papyrologie littéraire, notamment informatiques (Base de données Mertens-Pack³ et Leuven Database of Ancient Books). [less ▲]

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