Bluetongue in northern Europe.

in Veterinary Record : Journal of the British Veterinary Association (2006), 159(10), 327

Bluetongue Virus Detection By Real-Time Rt-Pcr In Culicoides Captured During The 2006 Epizootic In Belgium And Development Of An Internal Control

in Transboundary and Emerging Diseases (2009), 56(5), 170-177

Bluetongue Virus RNA Detection by Real-Time RT-PCR in Post-Vaccination Samples from Cattle.

in Transboundary and Emerging Diseases (2013)

Bluetongue virus serotype 8 (BTV-8) was responsible for a large outbreak among European ruminant populations in 2006-2009. In spring 2008, a massive vaccination campaign was undertaken, leading to the ... [more ▼]

Bluetongue virus serotype 8 (BTV-8) was responsible for a large outbreak among European ruminant populations in 2006-2009. In spring 2008, a massive vaccination campaign was undertaken, leading to the progressive disappearance of the virus. During surveillance programmes in Western Europe in 2010-2011, a low but significant number of animals were found weakly positive using BTV-specific real-time RT-PCR, raising questions about a possible low level of virus circulation. An interference of the BTV-8 inactivated vaccine on the result of the real-time RT-PCR was also hypothesized. Several studies specifically addressed the potential association between a recent vaccination and BTV-8 RNA detection in the blood of sheep. Results were contradictory and cattles were not investigated. To enlighten this point, a large study was performed to determine the risks of detection of bluetongue vaccine-associated RNA in the blood and spleen of cattle using real-time RT-PCR. Overall, the results presented clearly demonstrate that vaccine viral RNA can reach the blood circulation in sufficient amounts to be detected by real-time RT-PCR in cattle. This BTV-8 vaccine RNA carriage appears as short lasting. [less ▲]

Bluetongue: General introduction

in Bluetongue in northern Europe (2008)

"Blumenworte / Kriegsgestammel" - Rose Ausländer au Pays des Mots

in Culture, le Magazine Culturel de l'Université de Liège (2012)

Blunted growth hormone response to clonidine and apomorphine challenges in endogenous depression

in Shagass, Charles (Ed.) Biological Psychiatry 1985 (1985)

BLUPF90 and related programs (BGF90)

in Proceedings from the 7th World Congress on Genetics Applied to Livestock Production (2002)

Le BLV: un modele d'etude pour les leucemies humaines.

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2004), 159(10-12),

BM 34, an anticonvulsant sulfonylthiourea with a phenitoin-like profile

in Journal de Pharmacie de Belgique (1996), 51

BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase.

in Prostaglandins & Other Lipid Mediators (2011)

Atherosclerosis is the principal cause of mortality in industrialized countries. Its development is influenced by several mediators of which thromboxane A(2) (TXA(2)) and 8-iso-PGF(2() have recently ... [more ▼]

Atherosclerosis is the principal cause of mortality in industrialized countries. Its development is influenced by several mediators of which thromboxane A(2) (TXA(2)) and 8-iso-PGF(2() have recently received a lot of attention. This study aimed to investigate the effect of a dual thromboxane synthase inhibitor and thromboxane receptor antagonist (BM-573) and ASA on lesion formation in apolipoprotein E-deficient mice. The combination of ASA and BM-573 was also studied. Plasma measurements demonstrated that the treatments did not affect body weight or plasma cholesterol levels. BM-573, but not ASA, significantly decreased atherogenic lesions as demonstrated by macroscopic analysis. Both treatments alone inhibited TXB(2) synthesis but only BM-573 and the combination therapy were able to decrease firstly, plasma levels of soluble intracellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) and secondly, the expression of these proteins in the aortic root of Apo E. These results were confirmed in endothelial cell cultures derived from human saphenous vein endothelial cells (HSVECs). In these cells, BM-573 also prevented the increased mRNA expression of ICAM-1 and VCAM-1 induced by U-46619 and 8-iso-PGF(2(). Our results show that a molecule combining receptor antagonism and thromboxane synthase inhibition is more efficient in delaying atherosclerosis in Apo E(-/-) mice than sole inhibition of TXA(2) formation. [less ▲]