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See detailAvocado/soybean unsaponifiables prevent osteoarthritic subchondral osteoblasts-induced cartilage degradation
Sanchez, Christelle ULg; Deberg, Michelle ULg; Piccardi, Nathalie et al

in Osteoporosis International (2005), 16(Suppl.3), 56

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See detailAvocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes
Henrotin, Yves ULg; Deberg, Michelle ULg; Crielaard, Jean-Michel ULg et al

in Journal of Rheumatology (2006), 33(8), 1668-1678

Objective. To determine the effects of avocado/soybean unsaponifiables (ASU) on osteoblast-induced dysregulation of chondrocyte metabolism. Methods. Human chondrocytes were isolated from osteoarthritis ... [more ▼]

Objective. To determine the effects of avocado/soybean unsaponifiables (ASU) on osteoblast-induced dysregulation of chondrocyte metabolism. Methods. Human chondrocytes were isolated from osteoarthritis (OA) cartilage and cultured in alginate beads for 4 or 10 days in the absence or presence of osteoblasts isolated from nonsclerotic (NSC) or sclerotic (SC) zones of OA subchondral bone plate in monolayer. Before co-culture, osteoblasts were incubated or not with 10 mu g/ml ASU for 72 hours. Aggrecan, type 11 collagen, matrix metalloproteinase-3 (MMP-3) and MMP-13, tissue inhibitor of metalloproteinase (TIMP-1), transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 3, inducible NO synthase (iNOS), and cyclooxygenase-2 (COX-2) mRNA levels in chondrocytes were quantified by RT-PCR. Aggrecan, osteocalcin, TGF-beta 1, interleukin 18 (IL-1 beta), and IL-6 production were assayed by inummoassays. Results. In co-culture, SC osteoblasts induced a significant inhibition of matrix protein production and a significant increase of MMP synthesis by chondrocytes. In contrast, SC osteoblasts did not modify TIMP-1, TGF-beta 1 and TGF-beta 3, iNOS, or COX-2 mRNA levels in chondrocytes. The pretreatment of SC osteoblasts with ASU fully prevented the inhibitory effects of SC osteoblasts on matrix component production, and even significantly increased type 11 collagen mRNA level over the control (chondrocytes alone) value. In contrast, pretreatment of SC osteoblasts with ASU did not significantly modify the expression of NIMP, TIMP-1, TGF-beta 1, TGF-beta 3, iNOS, or COX-2 gene by chondrocytes. Conclusion. ASU prevent the osteoarthritic osteoblast-induced inhibition of matrix molecule production, suggesting that this compound may promote OA cartilage repair by acting on subchondral bone osteoblasts. This finding constitutes a new mechanism of action for this compound, known for its beneficial effects on cartilage. [less ▲]

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See detailAvocado/soybean unsaponifiables reverse H2O2 decoupling effect on aggrecan, type II collagen and metalloproteases gene expression in human chondrocytes
Mathy, Marianne ULg; Devel, P.; Piccardi, Nathalie et al

in Osteoarthritis and Cartilage (2003, October), 11(Suppl.1), 99

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See detailAvocat et assureur protection juridique : la fin des tensions ?
Paris, Catherine ULg

in Revue Générale des Assurances et des Responsabilités (2000)

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See detailL’Avocat général Colomer estime que le refus partiel de livrer opposé par un laboratoire à des grossistes en vue d’assécher le commerce parallèle n’est pas un abus per se, mais l’intention manifestement anticoncurrentielle crée une forte présomption d’abus
Sibony, Anne-Lise ULg

in Concurrences : Revue des Droits de la Concurrence (2008), 2

Conclusions de l’avocat général D. Ruiz-Jarabo Colomer, 1er avril 2008, Lélos e.a./Glaxosmithkline, C468/06 à C478/06 L’Avocat général Colomer estime que le refus partiel de livrer opposé par un ... [more ▼]

Conclusions de l’avocat général D. Ruiz-Jarabo Colomer, 1er avril 2008, Lélos e.a./Glaxosmithkline, C468/06 à C478/06 L’Avocat général Colomer estime que le refus partiel de livrer opposé par un laboratoire à des grossistes en vue d’assécher le commerce parallèle n’est pas un abus per se, mais l’intention manifestement anticoncurrentielle crée une forte présomption d’abus [less ▲]

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See detailL’avocat général Kokott est d’avis que, pour les abus consistant en une discrimination entre partenaires commerciaux, il doit être établi que la pratique de l’entreprise en position dominante crée un désavantage dans la concurrence pour l’un au moins des partenaires.
Sibony, Anne-Lise ULg

in Concurrences : Revue des Droits de la Concurrence (2011), 3-2011

Conclusion AG Kokott, 12 avril 2011, Solvay c/ Commission, aff. C-109/10P L’avocat général Kokott est d’avis que, pour les abus consistant en une discrimination entre partenaires commerciaux, il doit être ... [more ▼]

Conclusion AG Kokott, 12 avril 2011, Solvay c/ Commission, aff. C-109/10P L’avocat général Kokott est d’avis que, pour les abus consistant en une discrimination entre partenaires commerciaux, il doit être établi que la pratique de l’entreprise en position dominante crée un désavantage dans la concurrence pour l’un au moins des partenaires. [less ▲]

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See detailL’Avocat général Mazák conclut en ce sens que les autorités nationales de concurrence n’ont pas le pouvoir d’adopter des décisions négatives, constatant que les pratiques qui leur sont déférées ne constituent pas des violations de l’article 102 TFUE
Sibony, Anne-Lise ULg

in Concurrences : Revue des Droits de la Concurrence (2011), 1

Conclusions AG Mazàk, 7 décembre 2010, Tele 2 Polska, aff. C–375/09 L’Avocat général Mazák conclut en ce sens que les autorités nationales de concurrence n’ont pas le pouvoir d’adopter des décisions ... [more ▼]

Conclusions AG Mazàk, 7 décembre 2010, Tele 2 Polska, aff. C–375/09 L’Avocat général Mazák conclut en ce sens que les autorités nationales de concurrence n’ont pas le pouvoir d’adopter des décisions négatives, constatant que les pratiques qui leur sont déférées ne constituent pas des violations de l’article 102 TFUE. [less ▲]

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See detailL'avocat: un agent économique comme les autres?
Thirion, Nicolas ULg; Autenne, Alexia; Balate, Eric

in L'avocat. Mélanges Georges-Albert Dal (2013)

La contribution a pour objet de déterminer si l'avocat est un professionnel susceptible, en principe, d'être soumis au droit économique et, dans l'affirmative, si certaines spécificités de son activité ne ... [more ▼]

La contribution a pour objet de déterminer si l'avocat est un professionnel susceptible, en principe, d'être soumis au droit économique et, dans l'affirmative, si certaines spécificités de son activité ne doivent pas entraîner des exceptions à cette application du droit économique. [less ▲]

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See detailAvocats : entre pouvoir et contre-pouvoir
Delruelle, Edouard ULg

Conference given outside the academic context (2011)

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See detailLes avocats de l’O.B.F.G. Faits et chiffres
Devillet, Guénaël ULg; Charlier, J.; Merenne-Schoumaker, Bernadette ULg

in Actes du congrès de l’OBFG du 22 mars 2007 (2007)

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See detailAvocats, chanoines et lectures éclairées à Liège au XVIIIe siècle
Droixhe, Daniel ULg

in Trénard, L. (Ed.) Les bibliothèques au XVIIIe siècle (1989)

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See detailAvoided crossings: a study of the non-adiabatic transition probability
Desouter, Michèle ULg; Leyh-Nihant, Brigitte; Praet, Marie-Thérèse ULg et al

in Journal of Chemical Physics (1987), 86

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See detailAvoided overlap between two resonance energies or frequencies. Formation of fast and slow decay modes
Desouter, Michèle ULg; Jacques, Vincent

in Journal of Physics : B Atomic Molecular & Optical Physics (1995), 28

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See detailAvoided resonance overlapping beyond the energy independent formalism. I. Vibrational predissociation
Desouter, Michèle ULg; Liévin, Jacques; Brems, Vincent

in Journal of Chemical Physics (1995), 103

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See detailAvoided resonance overlapping beyond the energy independent formalism. II. Electronic predissociation
Brems, Vincent; Desouter, Michèle ULg; Liévin, Jacques

in Journal of Chemical Physics (1996), 104

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See detailAvoiding blood products during liver transplantation
Detry, Olivier ULg; De Roover, Arnaud ULg; Delwaide, Jean ULg et al

in Transplantation Proceedings (2005), 37(6, Jul-Aug), 2869-2870

Liver transplantation is a major surgical procedure usually requiring large amount of blood products (red cells, platelets, fresh-frozen plasma). We developed a multidisciplinary transfusion-free protocol ... [more ▼]

Liver transplantation is a major surgical procedure usually requiring large amount of blood products (red cells, platelets, fresh-frozen plasma). We developed a multidisciplinary transfusion-free protocol for liver transplantation in Jehovah's witnesses who refuse the use of blood products but accept organ transplantation. Between September 1998 and November 2004, 9 of 29 Jehovah's witnesses evaluated for liver transplantation were transplanted after medical preparation. None of these patients received any blood product during the surgical procedure. This experience may be beneficial for the entire liver transplantation population, as excessive transfusion has been linked to increased morbidity and mortality in liver transplantation. [less ▲]

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See detailAvoiding congestion in freight transport planning: a case study in Flanders
Caris, An; Cools, Mario ULg; Debels, Dieter

Conference (2011)

A substantial increase in transport intensity for passenger and freight traffic has been observed during the last decades and research confirms that this trend will continue in the years to come. Economic ... [more ▼]

A substantial increase in transport intensity for passenger and freight traffic has been observed during the last decades and research confirms that this trend will continue in the years to come. Economic centres have turned into heavily congested areas. The freight transport sector incurs excessive waiting times on the road as well as at intermediate stops (e.g. sea terminals, loading or unloading points). This may cause economic losses and environmental damages. Waiting times may be avoided by taking into account congestion in freight transport planning. Vehicle routing problems arise when several pickup and delivery operations need to be performed, mainly by truck, over relatively short distances [1]. Congestion leads to uncertain travel times on links and uncertain waiting times at pickup or delivery locations. Peak hours may be avoided on congested road segments by changing the order in which customers are served. On the other hand, time slots at customer sites may be renegotiated, creating more flexibility to avoid congestion on the road and at customer stops. The objective of this paper is to estimate the benefits of taking congestion into account in transport planning and to quantify the impact of delivery restrictions on transport costs. A highly congested road network raises the need for robust vehicle routing decisions. Current traffic conditions give rise to uncertain travel times. The reliability of travel time on a route is one of the dominant factors affecting route and departure time choices in passenger transport [2]. Similarly, in freight transport the reliability of travel times may be taken into account when planning vehicle routes. In this paper congestion is modelled as time-dependent travel times. These travel times take into account the dynamics of the time lost due to congestion using the Bureau of Public Roads (BPR) function, which is commonly-used for relating travel times to increases in travel volume [3]. The Time Dependent Vehicle Routing Problem (TDVRP) will be studied as a deterministic planning problem taking into account peak hour traffic congestion. Solution methods for the TDVRP have been focused on heuristic approaches [4, 5, 6, 7]. Kok [8] applies a restricted dynamic programming heuristic to solve a TDVRP. In this paper a heuristic algorithm will be presented to solve problem instances of realistic size. Next, this algorithm will be applied to perform a sensitivity analysis to identify which congestion avoiding strategies have a large influence on the objective function. Shippers may adapt the way they plan their transport as a strategy to avoid congestion. For example, time windows at customer locations may be renegotiated, departure times at the depot may be questioned or the assignment of customers to routes and the order in which customers are served may be changed. The proposed methodology will be demonstrated with a Flemish case study. [less ▲]

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