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Peer Reviewed
See detailAutobiographical memory and future thinking
D'Argembeau, Arnaud ULg

Conference (2010, June 15)

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See detailAutobiographical memory and problem solving in bipolar disorder
Boulanger, Marie ULg; Lejeune, Aurélie; Blairy, Sylvie ULg

Poster (2009, September)

Objective: The aim of the present study was to investigate the abilities to remember specific past personal events as well as the abilities to generate specific future events in patients with bipolar ... [more ▼]

Objective: The aim of the present study was to investigate the abilities to remember specific past personal events as well as the abilities to generate specific future events in patients with bipolar disorders (BD). Moreover, the study investigated whether the abilities to generate specific events is related to the abilities to solve interpersonal problems which was measured using the Optional Thinking Test (OTT) (Platt & Spivack, 1977). Method: Nineteen patients with bipolar disorders and 17 healthy subjects completed validated French versions (Neumann & Philippot, 2006) of the AMT Williams & Broadbent (1986). Participants were instructed to generate specific past and future memories in response to cues words. For the OTT, they were asked to yield the most solutions as possible to daily problems. Results: For the past events task, the analysis revealed a significant group by memory interaction (F(2,68) = 4.0 ; p=.023) which indicates that the patients with BD recollected less specific events and more overgeneral events than controls. For the future events task, a significant group by memory interaction emerged (F(2,68) = 7.85 ; p<.001) which indicates that the patients with BD were less specific and yielded more overgeneral memories than the control group. Further, the numbers of specific past and future events were correlated to the numbers of solutions to interpersonal problems (r(36) = .57 ; p<.001, r(36) = .43 ; p=.009, respectively). Conclusion: the results are consistent with previous studies that have examined autobiographical memory (AM) specificity in patients with BD (Scott et al., 2000; Mansell & Lam, 2004). These results support the notion of impairments in imagining specific past and future events BD patients. The difficulty in imagining the future may contribute to relapse. Thus, AM remediation program could be an additional useful tool to develop in CBT for bipolar patients. [less ▲]

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Peer Reviewed
See detailAutobiographical memory in non-amnesic alcohol-dependent patients
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; Verbanck, Paul et al

in Psychological Medicine (2006), 36(12), 1707-1715

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic ... [more ▼]

Background. Chronic alcohol abuse is associated with a wide range of cognitive deficits. However, little is known about memory for real-life events (autobiographical memory) in non-amnesic alcoholic patients. The purpose of this study was to investigate (a) non-amnesic alcoholics' ability to recall specific autobiographical memories and (b) their subjective experience when they access specific memories.Method. Twenty non-amnesic (without Korsakoff syndrome) recently detoxified alcoholics and 20 healthy controls completed the Autobiographical Memory Test (AMT), which assesses the frequency of specific (versus general) memories recalled in response to cue words, and the Memory Characteristics Questionnaire (MCQ), which assesses subjective experience (e.g. the amount of sensory and contextual details experienced) when remembering specific events.Results. Alcoholic patients recalled specific memories less frequently and general memories more frequently than healthy controls. Nevertheless, when a specific past event was accessed, alcoholic patients subjectively experienced as many sensory and contextual details as controls.Conclusions. These findings suggest that non-amnesic alcoholics have difficulties strategically accessing event-specific autobiographical knowledge, which might result from changes in frontal lobe function that are associated with alcoholism. [less ▲]

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Peer Reviewed
See detailAutobiographical remediation therapy in schizophrenia: results from an exploratory clinical training
Blairy, Sylvie ULg; Neumann, Aurore; Nachtergael, Hilde et al

Poster (2005, September)

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See detailAutobiographie
Viehöver, Vera ULg

in Jaeger, Friedrich (Ed.) Enzyklopädie der Neuzeit : Bd. 1: Abendland - Beleuchtung (2005)

Detailed reference viewed: 19 (3 ULg)
See detailAutobiographie d'Antoine Galland
Bauden, Frédéric ULg

in Le Journal d'Antoine Galland (1646-1715). La période parisienne. Vol. II (1710-1711) (2012)

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See detailL’Autobiographie polyphonique : Trois livres fondateurs
Dejasse, Erwin ULg

in Dejasse, Erwin; Habrand, Tanguy; Meesters, Gert (Eds.) L'Association : Une utopie éditoriale et esthétique (2011)

Cross-over study of three autobiographical comics: "Journal d'un album" by Dupuy and Berberian, "Approximativement" by Lewis Trondheim and "Livret de Phamille" by JC Menu.

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See detailAutobiographie posthume, autobiographie politique : A propos de Jean-Paul Sartre, Les Mots et autre écrits autobiographiques
Cormann, Grégory ULg

in Année Sartrienne (L') : Bulletin du Groupe d'Etudes Sartriennes (2011), 25

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See detailAutobiopoésie, Cliff, Verheggen, Delaive
Demoulin, Laurent ULg; Bertrand, Jean-Pierre ULg

in de la Torre, Estrella; Renouprez, Martine (Eds.) L'Autobiographie dans l'espace francophone I-la Belgique (2003)

La définition de l'autobiographie proposée par Lejeune restreint celle-ci à la prose. Qu'en est-il de ces trois poètes belges qui se racontent volontiers dans leurs écrits (Cliff, Verheggen, Delaive)?

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Peer Reviewed
See detailAutochtonus cases of piroplasmosis in Belgium and Northern France
Christmann, U; Sandersen, Charlotte ULg; Lhonneux, JF et al

in Proceedings of the 39th Annual Congress of the British Equine Veterinary Association (BEVA) (2000)

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Peer Reviewed
See detailAn autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.
Ahmed, Kashan; Tunaru, Sorin; Tang, Cong et al

in Cell Metabolism (2010), 11(4), 311-9

Lactate is an important metabolic intermediate released by skeletal muscle and other organs including the adipose tissue, which converts glucose into lactate under the influence of insulin. Here we show ... [more ▼]

Lactate is an important metabolic intermediate released by skeletal muscle and other organs including the adipose tissue, which converts glucose into lactate under the influence of insulin. Here we show that lactate activates the G protein-coupled receptor GPR81, which is expressed in adipocytes and mediates antilipolytic effects through G(i)-dependent inhibition of adenylyl cyclase. Using GPR81-deficient mice, we demonstrate that the receptor is not involved in the regulation of lipolysis during intensive exercise. However, insulin-induced inhibition of lipolysis and insulin-induced decrease in adipocyte cAMP levels were strongly reduced in mice lacking GPR81, although insulin-dependent release of lactate by adipocytes was comparable between wild-type and GPR81-deficient mice. Thus, lactate and its receptor GPR81 unexpectedly function in an autocrine and paracrine loop to mediate insulin-induced antilipolytic effects. These data show that lactate can directly modulate metabolic processes in a hormone-like manner, and they reveal a new mechanism underlying the antilipolytic effects of insulin. [less ▲]

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Peer Reviewed
See detailAn autocrine mechanism maintains persistent nuclear factor-kB activation in the bronchi of an animal model of asthma
Bureau, Fabrice ULg; Delhalle, S.; Bonizzi, G. et al

in Proceedings: International Conference of the American Thoracic Society (2000)

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Peer Reviewed
See detailAutocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM+) precursor cells from postnatal striatum.
Nguyen, Laurent ULg; Malgrange, Brigitte ULg; Breuskin, Ingrid ULg et al

in Journal of Neuroscience (2003), 23(8), 3278-94

GABA and its type A receptor (GABA(A)R) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study, on ... [more ▼]

GABA and its type A receptor (GABA(A)R) are present in the immature CNS and may function as growth-regulatory signals during the development of embryonic neural precursor cells. In the present study, on the basis of their isopycnic properties in a buoyant density gradient, we developed an isolation procedure that allowed us to purify proliferative neural precursor cells from early postnatal rat striatum, which expressed the polysialylated form of the neural cell adhesion molecule (PSA-NCAM). These postnatal striatal PSA-NCAM+ cells were shown to proliferate in the presence of epidermal growth factor (EGF) and formed spheres that preferentially generated neurons in vitro. We demonstrated that PSA-NCAM+ neuronal precursors from postnatal striatum expressed GABA(A)R subunits in vitro and in situ. GABA elicited chloride currents in PSA-NCAM+ cells by activation of functional GABA(A)R that displayed a typical pharmacological profile. GABA(A)R activation in PSA-NCAM+ cells triggered a complex intracellular signaling combining a tonic inhibition of the mitogen-activated protein kinase cascade and an increase of intracellular calcium concentration by opening of voltage-gated calcium channels. We observed that the activation of GABA(A)R in PSA-NCAM+ neuronal precursors from postnatal striatum inhibited cell cycle progression both in neurospheres and in organotypic slices. Furthermore, postnatal PSA-NCAM+ striatal cells synthesized and released GABA, thus creating an autocrine/paracrine mechanism that controls their proliferation. We showed that EGF modulated this autocrine/paracrine loop by decreasing GABA production in PSA-NCAM+ cells. This demonstration of GABA synthesis and GABA(A)R function in striatal PSA-NCAM+ cells may shed new light on the understanding of key extrinsic cues that regulate the developmental potential of postnatal neuronal precursors in the CNS. [less ▲]

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See detailL'autodestruction de la Raison comme histoire naturelle: Adorno, Horkheimer, Schelling
Zincq, Aurélien ULg

Conference (2013, December 04)

Detailed reference viewed: 16 (2 ULg)
See detailAutoficción y paratopía en la obra de Javier Cercas
Taormina, Alizé ULg

Conference (2013, October 08)

En esta comunicación, proponemos reflexionar sobre la autoficción hispánica desde la perspectiva de un concepto que resulta del análisis del discurso, la paratopía creadora. Mostraremos así, a través del ... [more ▼]

En esta comunicación, proponemos reflexionar sobre la autoficción hispánica desde la perspectiva de un concepto que resulta del análisis del discurso, la paratopía creadora. Mostraremos así, a través del caso del escritor español Javier Cercas, en qué medida el género autoficcional puede funcionar como un mecanismo de legitimación para el escritor contemporáneo, cuya figura, en la sociedad actual, tiende a hacerse cada vez más pequeña y banal (Alberca 2007: 24). Según Dominique Maingueneau, una de las características del discurso literario es ser paratópico, es decir, se enuncia desde un lugar paradójico basado en una doble imposibilidad: la de cerrarse sobre sí mismo, y la de confundirse con la sociedad ordinaria. Por consiguiente, el enunciador de un discurso literario no se puede colocar ni dentro, ni fuera de la sociedad: “il est voué à nourrir son œuvre du caractère radicalement problématique de sa propre appartenance à cette société” (Maingueneau 2004: 52). Así la paratopía no sólo caracteriza la condición de la literatura, sino también la de todo creador, quien precisamente se convierte en creador si asume, de manera singular, la paratopía constitutiva del discurso literario. Para ejemplificar nuestra hipótesis, consideraremos las dos autoficciones de Javier Cercas: Soldados de Salamina (2001) y La velocidad de la luz (2005). Veremos que, en estos textos, Cercas se crea una condición de escritor paratópico que no tiene en la vida real: el dispositivo ambiguo de la autoficción, que mezcla los registros ficcional y factual, le permite manipular el referente real y reescribir ciertos episodios de su vida de manera que la hace paratópica. Así se presenta bajo los rasgos de un artista bohemio o un escritor maldito, dos figuras paratópicas por excelencia, pero también se aproxima a personajes –la pitonisa, el veterano de Vietnam– y lugares –la residencia de ancianos, el campus universitario– atrapados en una pertenencia imposible: pertenecen y no pertenecen a la sociedad ordinaria. De esta manera, demostraremos cómo Cercas se atribuye, mediante su alter ego ficcional, cierta legitimidad, al inscribirse en situaciones paratópicas que su vida de hombre “normal” no le da. [less ▲]

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See detailL'autofiction de Javier Cercas: entre mythe et réalité
Taormina, Alizé ULg

Scientific conference (2013, June 01)

Detailed reference viewed: 36 (5 ULg)