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See detailBiological innovations and diversification of early eukaryotes
Javaux, Emmanuelle ULg

Conference (2006)

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See detailBiological oceanography and marine food webs: role of marine mammals and seabirds
Bouquegneau, Jean-Marie ULg; Debacker, Virginie ULg; Gobert, Sylvie ULg

in Jauniaux, Thierry; Bouquegneau, Jean-Marie; Coignoul, Freddy (Eds.) Marine Mammals, Seabirds and Pollution of Marine Systems (1997)

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See detailA biological pluridisciplinary model to predict municipal landfill life
Steyer, E.; Hiligsmann, Serge ULg; Radu, Jean-Pol ULg et al

in Christensen; Cossu; Stegmann (Eds.) Proceedings Sardinia 99, Seventh International Waste Management and Landfill Symposium (1999)

The degradation processes occurring within landfills are the keys to assessment and control of their environmental impact. This degradation results from different microbial activities interacting all ... [more ▼]

The degradation processes occurring within landfills are the keys to assessment and control of their environmental impact. This degradation results from different microbial activities interacting all along the landfill lifetime and influenced by several non-biological factors. Approaching these complex biological and chemical processes requires a multidisciplinary pattern. Thanks to Walloon Region support, we have developed a pattern or model combining the evolution of different key parameters. Such parameters qualify biogas (composition, production rate), leachate (pH, BOD5, COD, volatile fatty acids, redox potential, nitrogen balance, humic acids...), or solid waste (moisture, settlement, cellulose content...). This paper presents relationships, including our model, between these parameters. Variations of pH, BOD5/COD ratio, sulphate concentration in leachates and settlement measures allows to predict landfill age since completion. Evaluation of cellulose and water content in refuse as well as settlement degree are useful to estimate the time required for complete biological degradation. The mathematical model has also been applied, with success, to the case of Anton Sclayn site. [less ▲]

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See detailBiological properties of human prolactin analogs depend not only on global hormone affinity, but also on the relative affinities of both receptor binding sites
Kinet, Sandrina; Bernichtein, Sophie; Kelly, Paul A. et al

in Journal of Biological Chemistry (1999), 274(37), 26033-43

Zinc increases the affinity of human growth hormone (hGH) for the human prolactin receptor (hPRLR) due to the coordination of one zinc ion involving Glu-174(hGH) and His-18(hGH). In contrast, binding of ... [more ▼]

Zinc increases the affinity of human growth hormone (hGH) for the human prolactin receptor (hPRLR) due to the coordination of one zinc ion involving Glu-174(hGH) and His-18(hGH). In contrast, binding of hPRL to the hPRLR is zinc-independent. We engineered in binding site 1 of hPRL a hGH-like zinc coordination site, by mutating Asp-183(hPRL) (homologous to Glu-174(hGH)) into Glu (D183E mutation). This mutation was also introduced into G129R hPRL, a binding site 2 mutant (Goffin, V., Kinet, S., Ferrag, F., Binart, N., Martial, J. A. , and Kelly, P. A. (1996) J. Biol. Chem. 271, 16573-16579). These analogs were characterized using a stable clone expressing both the hPRLR and a PRLR-responsive reporter gene. The D183E mutation per se decreases the binding affinity and transcriptional activity of hPRL. However, this loss is partially rescued by the addition of zinc and the effect is much more marked on bioactivity than on binding affinity. These data indicate that the D183E mutation confers zinc sensitivity to hPRL biological properties. Due to an impaired site 2, the agonistic activity of G129R analog is almost nil. Although the double mutant D183E/G129R displays lower affinity ( approximately 1 log) compared with G129R hPRL, it unexpectedly recovers partial agonistic activity in the absence of zinc. Moreover, whereas zinc increases the affinity of D183E/G129R, it paradoxically abolishes its agonistic activity. Our results demonstrate that the biological properties of hPRL analogs do not necessarily parallel their overall affinity. Rather, the relative affinities of the individual binding sites 1 and 2 may play an even more important role. [less ▲]

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See detailBiological Reactions of oxido-reduction catalysed by microorganisms
De Wulf, O.; Jacques, Ph.; Thonart, Philippe ULg

Poster (1989, April)

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See detailBiological responses to CO2-related changes in seawater carbonate chemistry during a bloom of Emiliania huxleyi
Zondervan, Ingrid; Aerts, Katrien; Bellerby, Richard et al

Conference (2003, April 06)

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See detailBiological treatment of waste gypsum
Hiligsmann, Serge ULg; Jacques, Philippe; Thonart, Philippe ULg

in Biodegradation (1998)

The presentation presents the investigations about gypsum treatment by sulfate-reducing bacteria

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See detailBiological variations during a race cycling
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Goffaux, Sébastien et al

in Biomedica 2012 (2012, April)

Background: The metabolic and cardiac impact of a cycling effort on blood biology is not very well described in the literature. We aimed to measure the concentration of different biomarkers (cardiac and ... [more ▼]

Background: The metabolic and cardiac impact of a cycling effort on blood biology is not very well described in the literature. We aimed to measure the concentration of different biomarkers (cardiac and metabolic) released during an international cycling race. Materials and Methods: Venous blood samples of 15 young men (25.1 ± 6.4 y.o.) were collected just before (T1), just after (T2), 3 hours (T3) after an international cycling race of 176 kilometers in Belgium for the determination of cardiac and metabolic biomarkers: red blood cells (RBC) haemoglobin (HgB) creatinin (Cr) highly sensitive troponin T (hsTnT) myoglobin (MYO) NT-proBNP All automated assays were performed according to the manufacter’s specifications. For the statistical analysis, an Anova calculated with the Statistica Software version 9.1 was used. Results: •RBC and HgB levels varied significantly between T0 and T3 (respectively p=0.0026, and p=0.002) (Fig. 1 and 2). • Cr concentration also varied significantly between all times (T0-T1:p<0.0001, T1-T3:p=0.0326 and T0-T3 p=0.0001)(Fig.3). These changes might be related to renal flow depletion during exercise. •MYO increased significantly between T0 and T1 (p<0.0001), but quickly decreased between T1 and T3, however the T3 level stay higher than T0 (p=0.014) (Fig.4). •The stress delivered from the physical activity performed during the race induced a significant variation of hsTnT which increased significantly between T0 and T1 (p<0.0001) and stayed higher 3 hours after the end of the exercise (T0-T3: p<0.0001) (Fig.5) . •The intense exercise delivery by the race induced a significant variation of NT-proBNP, that followed the same kinetic of hsTnT but in smaller proportion. We noticed variations statistically significant between T0 and T1 and between T0 and T3 for NT-proBNP (Fig.6). •These increases of cardiac biomarkers were significant but reasonable and could not allow us to talk about cellular necrosis or irreversible injury. Conclusions: Our results show that stress generated by a cycling race could be the cause for the different metabolic variations observed. Troponin T stays without a doubt the most specific marker for stress related to myocardial tissue. Its increase can then be considered as being of interest. [less ▲]

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See detailBiological warfare and terrorism, the dark side of microbiology
Melin, Pierrette ULg

Scientific conference (2002, September)

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See detailBiological-Activity Of Fenoxycarb Against Sitophilus-Zeamais Motsch (Coleoptera, Curculionidae)
Letellier, C.; Haubruge, Eric ULg; Gaspar, Charles ULg

in Journal of Stored Products Research (1995), 31(1),

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See detailBIOLOGICAL-ACTIVITY OF THE SHRUB BOSCIA-SENEGALENSIS (PERS) LAM EX-POIR (CAPPARACEAE) ON STORED GRAIN INSECTS
SECK, D.; Lognay, Georges ULg; Haubruge, Eric ULg et al

in Journal of Chemical Ecology (1993), 19(2), 377-389

Biological activity of leaves, fruits and extract of the African shrub Boscia senegalensis (PERS.) LAM. ex Poir. was evaluated against five stored-grain insects. When added to cowpeas at 2-4% (w/w), fresh ... [more ▼]

Biological activity of leaves, fruits and extract of the African shrub Boscia senegalensis (PERS.) LAM. ex Poir. was evaluated against five stored-grain insects. When added to cowpeas at 2-4% (w/w), fresh ground fruits and leaves caused 80-100% mortality in Callosobruchus maculatus (F.) adults and significantly reduced both emergence and damage of the F1 progeny. Acetone fruit extract exhibited a potent fumigant effect on Prostephanus truncatus HORN., C maculatus, and Sitotroga cerealella OLIV.: with LT50 values of 3.8, 2.3, and below 1.5 hr, respectively. LC50 determination for B. senegalensis fruits and leaves as well as pure methylisothiocyanate (MITC) on Tribolium castaneum HERBST, Sitophilus zeamais MOTSCH. and C. maculatus showed a differential response of the insects to plant parts or MITC. Quantitative dosage of Boscia active components and LC50 values obtained for the plant tissues, compared to those of pure molecules, indicate that the biological activity of B. senegalensis is due to the liberation of MITC from a glucosinolate precursor glucocapparin contained in Boscia fruits and leaves. [less ▲]

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See detailBiologically active bisbenzylisoquinoline alkaloids from the root bark of Epinetrum villosum
Otshudi, A. L.; Apers, S.; Pieters, L. et al

in Journal of Ethnopharmacology (2005), 102(1), 89-94

Methanol and water extracts of the root of Epinetrum villosum (Exell) Troupin (Menispermaceae) were found to exhibit antimicrobial and antiplasmodial activities. Investigation of the active methanol ... [more ▼]

Methanol and water extracts of the root of Epinetrum villosum (Exell) Troupin (Menispermaceae) were found to exhibit antimicrobial and antiplasmodial activities. Investigation of the active methanol fraction led to the isolation of four bisbenzylisoquinoline alkaloids, i.e., cycleanine, cycleanine N-oxide, isochondodendrine and cocsoline. Structures were established by spectroscopic methods. Cocsoline displayed antibacterial and antifungal activities (MIC values of 1000-15.62 and 31.25 mu g/ml, respectively). Isochondodendrine was found to have the most potent antiplasmodial activity (IC50 = 0- 10 mu g/ml), whereas the IC50 on HCT-116 human colon carcinoma cells was 17.5 mu g/ml (selectivity index 175). Cycleanine acted against HIV-2 (EC50 = 1.83 mu g/ml) but was at least 10-fold less active against HIV-1. Cycleanine N-oxide showed no activity towards all tested microorganisms. (C) 2005 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailThe Biologically Important Surfactin Lipopeptide Induces Nanoripples In Supported Lipid Bilayers
Brasseur, Robert ULg; Braun, N.; El Kirat, K. et al

in Langmuir (2007), 23(19), 9769-72

Under specific conditions, lipid membranes form ripple phases with intriguing nanoscale undulations. Here, we show using in situ atomic force microscopy (AFM) that the biologically important surfactin ... [more ▼]

Under specific conditions, lipid membranes form ripple phases with intriguing nanoscale undulations. Here, we show using in situ atomic force microscopy (AFM) that the biologically important surfactin lipopeptide induces nanoripples of 30 nm periodicity in dipalmitoyl phosphatidylcholine (DPPC) bilayers at 25 degrees (i.e. well below the pretransition temperature of DPPC). Whereas most undulations formed the classical straight orientation with characteristic angle changes of 120 degrees , some of them also displayed unusual circular orientations. Strikingly, ripple structures were formed at 15% surfactin but were rarely or never observed at 5 and 30% surfactin, emphasizing the important role played by the surfactin concentration. Theoretical simulations corroborated the AFM data by revealing the formation of stable surfactin/lipid assemblies with positive curvature. [less ▲]

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See detailBiologically relevant association rules for classification of microarray data
Antonie, Luiza; Bessonov, Kyrylo ULg

in ACM SIGAPP Applied Computing Review (2012), 12(1), 12--23

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See detailA biologically-driven musical instrument
Arslan, B.; Brouse, A.; Castet, J. et al

in Proceedings of the 1st summer workshop on multimodal interfaces eNTERFACE05 (2005)

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See detailBiologie
Ruwet, Jean-Claude; Poncin, Pascal ULg

Learning material (1999)

Detailed reference viewed: 8 (0 ULg)
See detailBiologie au secondaire: quels enjeux, quels acquis, quels problèmes?
Hindryckx, Marie-Noëlle ULg

Scientific conference (2010, December 13)

Detailed reference viewed: 10 (1 ULg)
See detailBiologie clinique de l'infarctus du myocarde. Données nouvelles
Chapelle, Jean-Paul ULg

Conference (1982, February 25)

Detailed reference viewed: 9 (0 ULg)