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See detailAspetti prosodici e testuali del raccontare: dalla letteratura orale al parlato dei media
Moreno, Paola ULg; Di Salvo, Margherita

Conference (2014, January 23)

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See detailAsphalt concrete with fly ashes of different sources as filler replacement
Stroeven, Piet; He, Huan ULg; Huu Hanh, Pham

in Key Engineering Materials [=KEM] (2012), 517

Paper presents and discusses data obtained in a testing program on the replacement of limestone powder in asphalt concretes by fly ashes. This would combine economic, environmental and technical benefits ... [more ▼]

Paper presents and discusses data obtained in a testing program on the replacement of limestone powder in asphalt concretes by fly ashes. This would combine economic, environmental and technical benefits. The finest fly ash of Vietnamese origin scored best. This is proposed due to the gap-graded design of the particulate mixture of coarse crushed rock fractions, fine fluvial sand and the mineral admixture. The test program encompassed Marshall tests, creep tests and splitting tensile tests. [less ▲]

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See detailAspidothelium gemmiferum sp. nov., from Papua new Guinea (Lichenized Ascomycetes)
Sérusiaux, Emmanuël ULg; Lücking, Robert

in Mycotaxon (2001), 79

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See detailAspidothelium hirsutum (Thelenellaceae) and Caprettia goderei (Monoblastiaceae), two new species of foliicolous lichens from Ethiopia and Kenya
Yeshitela, Kumelachew; Fischer, Eberhard; Killmann, Dorothee et al

in Bryologist (2009), 112

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See detailASPIICS: an externally occulted coronagraph for PROBA-3.Design evolution.
Renotte, Etienne ULg; Carmen Baston, Elena; Bemporad, Alessandro et al

in SPIE 9143, Space Telescopes and Instrumentation 2014: Optical, Infrared, and Millimeter Wave (2014)

PROBA-3 is a mission devoted to the in-orbit demonstration of precise formation flying techniques and technologies for future ESA missions. PROBA-3 will fly ASPIICS (Association de Satellites pour ... [more ▼]

PROBA-3 is a mission devoted to the in-orbit demonstration of precise formation flying techniques and technologies for future ESA missions. PROBA-3 will fly ASPIICS (Association de Satellites pour l’Imagerie et l’Interferométrie de la Couronne Solaire) as primary payload, which makes use of the formation flying technique to form a giant coronagraph capable of producing a nearly perfect eclipse allowing to observe the sun corona closer to the rim than ever before. The coronagraph is distributed over two satellites flying in formation (approx. 150m apart). The so called Coronagraph Satellite carries the camera and the so called Occulter Satellite carries the sun occulter disc. This paper is reviewing the design and evolution of the ASPIICS instrument as at the beginning of Phase C/D. [less ▲]

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See detailL'Aspiration panoramique en cinéma : allers et retours
Belloi, Livio ULg

Scientific conference (2016, April 13)

Dans le cadre de cette intervention, il s'agit de revenir sur la question de la vue panoramique, selon un double mouvement d'aller et de retour. L'aller se produit aux origines du cinéma (Alexandre Promio ... [more ▼]

Dans le cadre de cette intervention, il s'agit de revenir sur la question de la vue panoramique, selon un double mouvement d'aller et de retour. L'aller se produit aux origines du cinéma (Alexandre Promio, George Albert Smith, Billy Bitzer); le retour est à débusquer du côté du cinéma expérimental contemporain (Pelechian, Morrison), sur le mode de la rémanence et de la variation. [less ▲]

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See detail« Aspirations minoritaires dans le contexte post-migratoire »,
Martiniello, Marco ULg

Scientific conference (2011, May 12)

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See detailAspirin and clopidogrel resistance in patients with diabetes mellitus.
Scheen, André ULg; Legrand, Delphine ULg

in European Heart Journal (2006), 27(23), 29002900-1

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See detailL'aspirine en prevention primaire des maladies cardio-vasculaires chez le patient diabetique.
Legrand, Delphine ULg; Scheen, André ULg

in Revue Médicale de Liège (2006), 61(10), 682-90

Acetylsalicylic acid (aspirin) is widely used as antiplatelet therapy for the primary and secondary prevention of cardiovascular diseases. However, the effects appear to be different according to the ... [more ▼]

Acetylsalicylic acid (aspirin) is widely used as antiplatelet therapy for the primary and secondary prevention of cardiovascular diseases. However, the effects appear to be different according to the studied population, with a reduction of coronary events in men and, rather, a diminution of strokes in women. Diabetes mellitus markedly increases the risk of cardiovascular diseases, with an especially elevated relative risk among women. We present a detailed analysis of the literature about the efficacy of aspirin in the primary prevention of cardiovascular complications in the diabetic population. Limited available data suggest a lower protection in the diabetic than in the non-diabetic population. A greater aspirin resistance has been suggested in diabetic patents, which might lead to the use of a higher daily dosage of aspirin in diabetic than in non diabetic patients. Whatsoever, aspirin remains the first antiplatelet agent in the diabetic population in all international guidelines of cardiovascular prevention. [less ▲]

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See detailAsporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
Maris, Pamela; Blomme, Arnaud; Palacios, Ana Perez et al

in PLoS medicine (2015), 12(9), 1001871

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-beta1 has been identified as a key ... [more ▼]

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-beta1 has been identified as a key driving force behind metastatic breast cancer, with promising therapeutic implications. METHODS AND FINDINGS: Employing immunohistochemistry (IHC) analysis, we report, to our knowledge for the first time, that asporin is overexpressed in the stroma of most human breast cancers and is not expressed in normal breast tissue. In vitro, asporin is secreted by breast fibroblasts upon exposure to conditioned medium from some but not all human breast cancer cells. While hormone receptor (HR) positive cells cause strong asporin expression, triple-negative breast cancer (TNBC) cells suppress it. Further, our findings show that soluble IL-1beta, secreted by TNBC cells, is responsible for inhibiting asporin in normal and cancer-associated fibroblasts. Using recombinant protein, as well as a synthetic peptide fragment, we demonstrate the ability of asporin to inhibit TGF-beta1-mediated SMAD2 phosphorylation, epithelial to mesenchymal transition, and stemness in breast cancer cells. In two in vivo murine models of TNBC, we observed that tumors expressing asporin exhibit significantly reduced growth (2-fold; p = 0.01) and metastatic properties (3-fold; p = 0.045). A retrospective IHC study performed on human breast carcinoma (n = 180) demonstrates that asporin expression is lowest in TNBC and HER2+ tumors, while HR+ tumors have significantly higher asporin expression (4-fold; p = 0.001). Assessment of asporin expression and patient outcome (n = 60; 10-y follow-up) shows that low protein levels in the primary breast lesion significantly delineate patients with bad outcome regardless of the tumor HR status (area under the curve = 0.87; 95% CI 0.78-0.96; p = 0.0001). Survival analysis, based on gene expression (n = 375; 25-y follow-up), confirmed that low asporin levels are associated with a reduced likelihood of survival (hazard ratio = 0.58; 95% CI 0.37-0.91; p = 0.017). Although these data highlight the potential of asporin to serve as a prognostic marker, confirmation of the clinical value would require a prospective study on a much larger patient cohort. CONCLUSIONS: Our data show that asporin is a stroma-derived inhibitor of TGF-beta1 and a tumor suppressor in breast cancer. High asporin expression is significantly associated with less aggressive tumors, stratifying patients according to the clinical outcome. Future pre-clinical studies should consider options for increasing asporin expression in TNBC as a promising strategy for targeted therapy. [less ▲]

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See detailL'assainissement viral des bananiers: une étape primordiale dans la préservation de la biodiveristé
Lassois, Ludivine ULg; Castaigne, Michel; D'haes, François

Diverse speeche and writing (2010)

Le laboratoire de Phytopathologie de Gembloux Agro-Bio Tech a développé les techniques permettant la détection et l’assainissement des plantules de bananiers virosés. Ce laboratoire travaille en étroite ... [more ▼]

Le laboratoire de Phytopathologie de Gembloux Agro-Bio Tech a développé les techniques permettant la détection et l’assainissement des plantules de bananiers virosés. Ce laboratoire travaille en étroite collaboration avec Bioversity International afin de fournir au Centre de Transit International, et à fortiori à la communauté internationale, des bananiers indemnes de virus. Les bananiers ainsi obtenus peuvent donc être diffusés largement sans craintes d’une épidémie quelconque. Ce travail d’assainissement contribue non seulement à la sauvegarde de la biodiversité mais également à sa valorisation en rendant saines des variétés qui étaient virosées et non exploitables. Jusqu’à présent l’ITC a fourni 15 000 plantules saines de bananiers dans 335 régions réparties dans 100 pays. Ce travail conjoint de conservation et d’assainissement permet de valoriser la grande diversité génétique du bananier au service de la communauté internationale. [less ▲]

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Peer Reviewed
See detailAssay for radiolabeled type IV collagen in the presence of other proteins using a specific collagenase.
Garbisa, S.; Tryggvason, K.; Foidart, Jean-Michel ULg et al

in Analytical Biochemistry (1980), 107(1), 187-92

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See detailAssay of Matrix Metalloproteinases Types 1, 2, 3 and 9 in Breast Cancer
Remacle, A. G.; Noël, Agnès ULg; Duggan, C. et al

in British Journal of Cancer (1998), 77(6), 926-31

Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases implicated in cancer invasion and metastasis. Gelatin zymography was performed on 84 human breast carcinomas and seven normal breast ... [more ▼]

Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases implicated in cancer invasion and metastasis. Gelatin zymography was performed on 84 human breast carcinomas and seven normal breast tissues. The precursor form of MMP-2 (72 kDa) was found in 11 (12%) samples, while its two activated forms, i.e. 62 kDa and 59 kDa, were found in three (6%) and 34 (40%) samples respectively. In contrast to MMP-2, most of the samples (52%) contained MMP-9 in its precursor form. Using ELISA, MMP-1 levels were found in 12% of the samples while MMP-3 levels were found in only 2% of the samples. Levels of MMP-2, -3 and -9 correlated inversely with numbers of nodal metastases. Neither MMP-2 nor -9 levels were significantly related to patient outcome. However, patients with high levels of a 50-kDa gelatinase band after zymography had a significantly better survival than patients with low levels. This species was never observed in normal breast tissue. [less ▲]

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See detailAssemblage de tôles minces par clinchage en construction métallique
Pietrapertosa, Carlo; Habraken, Anne ULg; Jaspart, Jean-Pierre ULg

Report (2005)

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See detailAssemblage moléculaire électro-assisté d’organothiols mono- et bipodes sur cuivre
Maho, Anthony ULg; Denayer, Jessica; Delhalle, Joseph et al

Conference (2010)

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See detailAssemblage-moléculaire électro-assisté d'organothiols sur cuivre polycristallin
Maho, Anthony ULg; Denayer, Jessica ULg; Delhalle, Joseph et al

in Chimie Nouvelle (2011), 5

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See detailAssembly and concept of a web-based GIS within the paleolimnological project CONTINENT (Lake Baikal, Russia)
Heim, Birgit; Klump, Jens; Oberhaensli, Hedi et al

in Journal of Paleolimnology (2008), 39(4), 567-584

Web-based Geographical Information Systems (GIS) are excellent tools within interdisciplinary and multi-national geoscience projects to exchange and visualize project data. The web-based GIS presented in ... [more ▼]

Web-based Geographical Information Systems (GIS) are excellent tools within interdisciplinary and multi-national geoscience projects to exchange and visualize project data. The web-based GIS presented in this paper was designed for the paleolimnological project 'High-resolution CONTINENTal paleoclimate record in Lake Baikal' (CONTINENT) (Lake Baikal, Siberia, Russia) to allow the interactive handling of spatial data. The GIS database combines project data (core positions, sample positions, thematic maps) with auxiliary spatial data sets that were downloaded from freely available data sources on the world wide web. The reliability of the external data was evaluated and suitable new spatial datasets were processed according to the scientific questions of the project. GIS analysis of the data was used to assist studies on sediment provenance in Lake Baikal, or to help answer questions such as whether the visualization of present-day vegetation distribution and pollen distribution supports the conclusions derived from palynological analyses. The refined geodata are returned back to the scientific community by using online data publication portals. Data were made citeable by assigning persistent identifiers (DOI) and were published through the German National Library for Science and Technology (TIB Hannover, Hannover, Germany). [less ▲]

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See detailThe assembly of a farm meat network in Belgium and risk
Stassart, Pierre M ULg

Conference (2001)

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See detailAssembly of enveloped RNA viruses
Dubois-Dalcq, Monique; Holmes, Kathryn V; Rentier, Bernard ULg

Book published by Springer Verlag (1985)

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See detailAssembly of Ligand-Stripped Nanocrystals into Precisely Controlled Mesoporous Architectures
Buonsanti, R.; Pick, T. E.; Krins, Natacha ULg et al

in Nano Letters (2012), 12

Detailed reference viewed: 16 (2 ULg)