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See detailAspects zootechniques et économiques de l’utilisation des feuilles de Vitellaria paradoxa et de tourteau de coton en supplémentation sur la production laitière de la vache Borgou en saison hivernale
Chabi Toko, Roukayath ULg

Master's dissertation (2005)

Experiment was carried out to investigate the effects of cottonseed meal (CSM) and Vitellaria paradoxa leaves in rainy season supplementation on milk yield, composition of the milk, live weight changes ... [more ▼]

Experiment was carried out to investigate the effects of cottonseed meal (CSM) and Vitellaria paradoxa leaves in rainy season supplementation on milk yield, composition of the milk, live weight changes and their economical returns. To examine these effects, fifteen (15) Borgou cattle, in late lactation were offered three (3) dietary treatments: grazing natural pasture (control); the two other treatments received in addition cottonseed meal and Vitellaria paradoxa leaves supplements. The experiment lasted ten (10) weeks, including an adaptation period of two (2) weeks. Average daily milk yield was 946,58 g, 1690,07 g and 1176,89 g for the control, cottonseed meal and Vitellaria paradoxa leaves group respectively. Dietary treatments had a significant (p< 0,05) effect on milk yield during the trial. Only cows supplemented CSM produce significantly more milk than those unsupplemented (increasing of 78,54 %). But there is no differences among supplemented group. Cottonseed meal group produce more than 43,60 % milk yield compared to the second supplemented group. The treatments had a significant effect on total solid and milk ash. But no significant effect was observed on fat and protein content. The over all mean values were 15,12 %, 0,35 %, 5,92 % and 4,13 % respectively for total solid, ash, fat and protein content. There were no significant differences (p<0,05) in live weight changes of supplemented group cows. Further more, calves live weight changes were significantly different. Supplemented groups calves live weight increase was significantly more than those unsupplemented from birth to the end of the trial (212,06 g/d and 219,10 g/d versus 161,1 g/d). From birth to the beginning of the trial, only Vitellaria paradoxa leaves group calves had a significant increase in live weight changes. Only CSM group calves had a significant increase in live weight changes (124,98 g/d versus 53,54 g/d for non supplemented group calves) during the trial. Calves live weight changes from birth to the beginning of the trial were highly significantly correlated with those from birth to the end of the trial for all the experimental herd and for CSM group (r = 0,96 and r = 0,99). In other hand, these two live weight changes were slightly correlated for the control (r = 0,96) and Vitellaria paradoxa group (r = 0,97). A net return analysis shows that cottonseed meal and Vitellaria paradoxa supplementation in rainy season was profitable even if Vitellaria paradoxa was more beneficial. [less ▲]

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See detailAspectualité et actionalité. Essai sur la temporalité en égyptien ancien
Winand, Jean ULg

Post doctoral thesis (2002)

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See detailAspekte der Sprachursprungsproblematik in Frankreich in der zweiten Hälfte des 18. Jahrhunderts
Droixhe, Daniel ULg

in Gessinger, J.; von Rahden, W. (Eds.) Theorien vom Ursprung der Sprache. Band 1 (1989)

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See detailASPERGER SYNDROME: Clinical picture at a 5-year-old boy and diagnostic work of assessment.
Philippe, Paule ULg; Scholl, Jean-Marc ULg

Poster (2008, October)

The child's parents consulted the Liege Autism Référence Center at Liège in 2007; the child was 5 years old. The main difficulties arise at school: the child does not follow the orders, disrupts the class ... [more ▼]

The child's parents consulted the Liege Autism Référence Center at Liège in 2007; the child was 5 years old. The main difficulties arise at school: the child does not follow the orders, disrupts the class; but except the school, he is very curious to learn, he possesses a surprising vocabulary and memory at his age The multidisciplinary team realized the clinical diagnostic work of assessment (neuropsychological tests, observations at school, at home, during consultations).The various examinations realized previously were consulted and gathered. This poster resume parents observations, assesment results, hypothesis of neurophysiology,of diagnosis following DSM IV, Zero to Three .It's present also our proposition of coverage(care) and orientation. [less ▲]

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See detailAspergillose chez les oiseaux marins échoués sur la côte belge
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Annales de Médecine Vétérinaire (1994), 138(4), 277-281

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species ... [more ▼]

Pulmonary aspergillosis is a respiratory disease usually present in birds. The agent is an ubiquitous and saprophitic fungus, belonging to the Aspergillus genus, A. fumigatus being the predominant species. Debilitation and stress are favourable for the mycosis installation in captive wild birds (Zoo and rehabilitation centers). During 90-91 and 91-92 winters, 386 birds found dead at the belgian seashore were necropsied and 9 birds were carriers of specific lesions. Complementary investigations were undertaken. Most animals were oiled and had been kept for some time in rehabilitation centers. [less ▲]

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See detailL’aspergillose naso-sinusale chez le chien
Billen, Frédéric ULg; Peeters, Dominique ULg; Clercx, Cécile ULg

in Monde Vétérinaire (Le) (2010), 107

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See detailL’aspergillose naso-sinusale dans l’espèce canine
Peeters, Dominique ULg; Clercx, Cécile ULg

in Annales de Médecine Vétérinaire (2004), 148(4), 168-173

Canine sino-nasal aspergillosis is a common cause of chronic nasal discharge. The pathogenesis of the disease is not well understood but factors associated to the fungus and to the host are implicated ... [more ▼]

Canine sino-nasal aspergillosis is a common cause of chronic nasal discharge. The pathogenesis of the disease is not well understood but factors associated to the fungus and to the host are implicated. Even if computed tomography and magnetic resonance imaging have been proved valuable in differentiating sino-nasal aspergillosis from neoplasia, the definitive diagnosis of the disease requires visualisation of the fungus either by rhinoscopy, cytology or histology. The best treatment involves topical administration of antifungal drugs. The long-term prognosis is guarded to good. [less ▲]

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See detailAspergillosis
Clercx, Cécile ULg

in Proceedings of the 24th Program -Symposium on diseases of small animals - Portoroz - Slovenia (2011, April)

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See detailAspergillosis in cats : ABCD guidelines on prevention and management
Hartmann; Lloret, A.; Pennisi, M.G. et al

in Journal of Feline Medicine and Surgery (2013), 15

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See detailAspergillus fumigatus detection by PCR in broncho-alveolar fluid
Hayette, Marie-Pierre ULg; Boland, Pascal; Evrard, Béatrice et al

Poster (1999, September 29)

Background: The usefullness of a nested PCR for detection of Aspergillus fumigatus DNA was evaluated in bronchoalveolar lavage (BAL) fluid during a period of two years (1996- 1998). The aim of the study ... [more ▼]

Background: The usefullness of a nested PCR for detection of Aspergillus fumigatus DNA was evaluated in bronchoalveolar lavage (BAL) fluid during a period of two years (1996- 1998). The aim of the study was to assess the role of PCR in diagnosing invasive pulmonary aspergillosis (IPA). Methods: A nested PCR-based amplification of fragments of genes-encoding alkaline proteases from A. fumigatus was used to test 167 BAL samples. All samples were checked for the absence of amplification inhibitors. Medical, radiological, microbiological records and autopsy findings were reviewed for assessing invasive aspergillosis. All successive patients investigated by BAL were included in the study. They were distributed in three groups: A, proven or probable aspergillosis (n=11); B, colonization (n=2); C, no evidence of IPA (n=154). PCR results were compared to culture détection as gold standard and to clinical data. Results: BAL fluids from 10 patients of group A were PCR positive. One case was falsely negative. Among group B, one case was PCR positive, and the second one PCR negative but had negative BAL cultures (only culture positive sputum). No false positive was detected among group C. Comparing to culture, sensitivity was 91%, specificity, 100%, positive predictive value, 100% and négative predictive value, 99%. Conclusion: 1. Aspergillus fumigatus PCR in BAL fluid was an accurate test to diagnose culture negative patients with IPA and to confirm culture positive samples; however it doesn't make difference between infection and colonization. 2. It is an appropriate test to exclude Aspergillus infection in patients at risk of invasive illness. [less ▲]

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See detailAspergillus: still the same as before?
Hayette, Marie-Pierre ULg

Conference (2010, October 07)

La présentation fait le point sur les évolutions touchant les Aspergillus depuis une vingtaine d'années sur les plan taxonomique, épidémiologique, clinique et thérapeutique.

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See detailAspetti prosodici e testuali del raccontare: dalla letteratura orale al parlato dei media
Moreno, Paola ULg; Di Salvo, Margherita

Conference (2014, January 23)

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See detailAsphalt concrete with fly ashes of different sources as filler replacement
Stroeven, Piet; He, Huan ULg; Huu Hanh, Pham

in Key Engineering Materials [=KEM] (2012), 517

Paper presents and discusses data obtained in a testing program on the replacement of limestone powder in asphalt concretes by fly ashes. This would combine economic, environmental and technical benefits ... [more ▼]

Paper presents and discusses data obtained in a testing program on the replacement of limestone powder in asphalt concretes by fly ashes. This would combine economic, environmental and technical benefits. The finest fly ash of Vietnamese origin scored best. This is proposed due to the gap-graded design of the particulate mixture of coarse crushed rock fractions, fine fluvial sand and the mineral admixture. The test program encompassed Marshall tests, creep tests and splitting tensile tests. [less ▲]

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See detailAspidothelium gemmiferum sp. nov., from Papua new Guinea (Lichenized Ascomycetes)
Sérusiaux, Emmanuël ULg; Lücking, Robert

in Mycotaxon (2001), 79

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See detailAspidothelium hirsutum (Thelenellaceae) and Caprettia goderei (Monoblastiaceae), two new species of foliicolous lichens from Ethiopia and Kenya
Yeshitela, Kumelachew; Fischer, Eberhard; Killmann, Dorothee et al

in Bryologist (2009), 112

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See detailL'Aspiration panoramique en cinéma : allers et retours
Belloi, Livio ULg

Scientific conference (2016, April 13)

Dans le cadre de cette intervention, il s'agit de revenir sur la question de la vue panoramique, selon un double mouvement d'aller et de retour. L'aller se produit aux origines du cinéma (Alexandre Promio ... [more ▼]

Dans le cadre de cette intervention, il s'agit de revenir sur la question de la vue panoramique, selon un double mouvement d'aller et de retour. L'aller se produit aux origines du cinéma (Alexandre Promio, George Albert Smith, Billy Bitzer); le retour est à débusquer du côté du cinéma expérimental contemporain (Pelechian, Morrison), sur le mode de la rémanence et de la variation. [less ▲]

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See detail« Aspirations minoritaires dans le contexte post-migratoire »,
Martiniello, Marco ULg

Scientific conference (2011, May 12)

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See detailAspirin and clopidogrel resistance in patients with diabetes mellitus.
Scheen, André ULg; Legrand, Delphine ULg

in European Heart Journal (2006), 27(23), 29002900-1

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See detailL'aspirine en prevention primaire des maladies cardio-vasculaires chez le patient diabetique.
Legrand, Delphine ULg; Scheen, André ULg

in Revue Médicale de Liège (2006), 61(10), 682-90

Acetylsalicylic acid (aspirin) is widely used as antiplatelet therapy for the primary and secondary prevention of cardiovascular diseases. However, the effects appear to be different according to the ... [more ▼]

Acetylsalicylic acid (aspirin) is widely used as antiplatelet therapy for the primary and secondary prevention of cardiovascular diseases. However, the effects appear to be different according to the studied population, with a reduction of coronary events in men and, rather, a diminution of strokes in women. Diabetes mellitus markedly increases the risk of cardiovascular diseases, with an especially elevated relative risk among women. We present a detailed analysis of the literature about the efficacy of aspirin in the primary prevention of cardiovascular complications in the diabetic population. Limited available data suggest a lower protection in the diabetic than in the non-diabetic population. A greater aspirin resistance has been suggested in diabetic patents, which might lead to the use of a higher daily dosage of aspirin in diabetic than in non diabetic patients. Whatsoever, aspirin remains the first antiplatelet agent in the diabetic population in all international guidelines of cardiovascular prevention. [less ▲]

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See detailAsporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
Maris, Pamela; Blomme, Arnaud; Palacios, Ana Perez et al

in PLoS medicine (2015), 12(9), 1001871

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-beta1 has been identified as a key ... [more ▼]

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-beta1 has been identified as a key driving force behind metastatic breast cancer, with promising therapeutic implications. METHODS AND FINDINGS: Employing immunohistochemistry (IHC) analysis, we report, to our knowledge for the first time, that asporin is overexpressed in the stroma of most human breast cancers and is not expressed in normal breast tissue. In vitro, asporin is secreted by breast fibroblasts upon exposure to conditioned medium from some but not all human breast cancer cells. While hormone receptor (HR) positive cells cause strong asporin expression, triple-negative breast cancer (TNBC) cells suppress it. Further, our findings show that soluble IL-1beta, secreted by TNBC cells, is responsible for inhibiting asporin in normal and cancer-associated fibroblasts. Using recombinant protein, as well as a synthetic peptide fragment, we demonstrate the ability of asporin to inhibit TGF-beta1-mediated SMAD2 phosphorylation, epithelial to mesenchymal transition, and stemness in breast cancer cells. In two in vivo murine models of TNBC, we observed that tumors expressing asporin exhibit significantly reduced growth (2-fold; p = 0.01) and metastatic properties (3-fold; p = 0.045). A retrospective IHC study performed on human breast carcinoma (n = 180) demonstrates that asporin expression is lowest in TNBC and HER2+ tumors, while HR+ tumors have significantly higher asporin expression (4-fold; p = 0.001). Assessment of asporin expression and patient outcome (n = 60; 10-y follow-up) shows that low protein levels in the primary breast lesion significantly delineate patients with bad outcome regardless of the tumor HR status (area under the curve = 0.87; 95% CI 0.78-0.96; p = 0.0001). Survival analysis, based on gene expression (n = 375; 25-y follow-up), confirmed that low asporin levels are associated with a reduced likelihood of survival (hazard ratio = 0.58; 95% CI 0.37-0.91; p = 0.017). Although these data highlight the potential of asporin to serve as a prognostic marker, confirmation of the clinical value would require a prospective study on a much larger patient cohort. CONCLUSIONS: Our data show that asporin is a stroma-derived inhibitor of TGF-beta1 and a tumor suppressor in breast cancer. High asporin expression is significantly associated with less aggressive tumors, stratifying patients according to the clinical outcome. Future pre-clinical studies should consider options for increasing asporin expression in TNBC as a promising strategy for targeted therapy. [less ▲]

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