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See detailRepeated cadmium nebulizations induce pulmonary MMP-2 and MMP-9 production and emphysema in rats.
Kirschvink, Nathalie; Vincke, Gregoire; Fievez, Laurence ULg et al

in Toxicology (2005), 211(1-2), 36-48

This study describes induction of pulmonary inflammation, production of matrix metalloprotease of type 2 (MMP-2) and type 9 (MMP-9), and emphysema in cadmium (Cd)-exposed rats. Sprague-Dawley rats were ... [more ▼]

This study describes induction of pulmonary inflammation, production of matrix metalloprotease of type 2 (MMP-2) and type 9 (MMP-9), and emphysema in cadmium (Cd)-exposed rats. Sprague-Dawley rats were randomly distributed into two groups: one placebo-exposed group undergoing saline (NaCl 0.9%) inhalation (n=30) and one Cd-exposed group undergoing cadmium (CdCl(2) 0.1%) inhalation (n=30). The animals of the placebo- and Cd-exposed groups were divided in five subgroups (n=6). Subgroups underwent either a single exposure of 1h or repeated exposures three times weekly for 1h during 3 weeks (3W), 5 weeks (5W), 5 weeks followed by 2 weeks without exposure (5W+2) or 5 weeks followed by 4 weeks without exposure (5W+4). Each animal underwent determination of enhanced pause (Penh) as index of airflow limitation prior to the first exposure as well as before sacrifice. The animals were sacrificed the day after their last exposure. The left lung was fixed for histomorphometric analysis (determination of median interwall distance (MIWD)), whilst bronchoalveolar lavage fluid (BALF) was collected from the right lung. BALF was analyzed cytologically, and MMP-2 and MMP-9 levels were determined by gelatine zymography. Twelve rats previously instilled with pancreatic elastase were used as positive emphysema controls and underwent the same investigations. Cd-exposure induced a significant increase of BALF macrophages, neutrophils and MMP-9 up to 5W+4, whereas MMP-2 gelatinolytic activity returned to baseline levels within 5W. MIWD was significantly increased in all repeatedly Cd-exposed groups and elastase-treated rats. Penh was increased in Cd-exposed rats after a single exposure and after 3W. MMP gelatinolytic activity was significantly correlated with macrophages, neutrophils and Penh. In repeatedly exposed rats, MIWD was positively and significantly correlated with MMP gelatinolytic activity, suggesting that increased MMP-2 and MMP-9 production favours the development of emphysema. [less ▲]

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See detailRepeated cycles of DSS inducing a chronically relapsing inflammation: a novel model to study fibrosis using in vivo MRI T2 relaxometry
Breynaert, C; Dresselaers, T; Cremer, J et al

Poster (2012, May)

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See detailRepeated cycles of DSS inducing a chronically relapsing inflammation: A novel model to study fibrosis using in vivo MRI T2 relaxometry
Breynaert, C; Dresselaers, T; Cremer, J et al

Poster (2012, February)

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See detailRepeated Cycles of Retrovirus-Mediated Hsvtk Gene Transfer Plus Ganciclovir Increase Survival of Rats with Peritoneal Carcinomatosis
Princen, Frédéric; Lechanteur, Chantal ULg; Lopez Y Cadenas, Miguel ULg et al

in Gene Therapy (1998), 5(8), 1054-60

Peritoneal carcinomatosis is a common clinical situation that requires novel therapeutic approaches. We investigated the efficiency of an HSVtk gene therapy for the treatment of peritoneal carcinomatosis ... [more ▼]

Peritoneal carcinomatosis is a common clinical situation that requires novel therapeutic approaches. We investigated the efficiency of an HSVtk gene therapy for the treatment of peritoneal carcinomatosis induced in syngeneic rats by DHD/K12 colon carcinoma cells. In this setting, the efficiency of two different retrovirus producing cell lines (GP+AmEnv12 and FLYA13) was compared. Rats treated with a single injection of retrovirus producing cells followed by a 5-day course of ganciclovir treatment showed an increased survival as compared with control animals. Animals treated with three injections of producing cells, each followed by a 4-5-day course of ganciclovir treatment, showed an increased survival as compared with control rats and with those treated with a single cycle of retrovirus producing cells plus ganciclovir. However, only a few animals remained tumor-free after day 180. There was no difference between the two producing cell lines in any of the experiments. RT-PCR demonstrated a faint expression of the tk transgene in the liver, spleen, epiploon, bowels and the lung of the animals injected with the HSVtk producing cells, reflecting most likely the transduction of only a limited number of cells. [less ▲]

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See detailRepeated high doses administration of eCG in cows submitted to an ovum pick-up experimental protocol: plasmatic eCG binding rate follow up
Drion, Pierre ULg; De Roover, R.; Houtain JY et al

(1997, September 12)

This study performed plasma eCG binding rates assay on 8 cows submitted to repeated and high doses eCG administration in an ovum pick-up experimental protocol (de Roover et al., Abs.). The cows were ... [more ▼]

This study performed plasma eCG binding rates assay on 8 cows submitted to repeated and high doses eCG administration in an ovum pick-up experimental protocol (de Roover et al., Abs.). The cows were divided in two groups. For each cow, blood samples were taken three times a week, before and during the period of treatments. Cows of the first group received 10 injections of eCG (2000UI; 4x1000 UI; 5x2000 UI) while cows of the second group received 5 eCG treatments (2000 UI).Statistical analysis of results was made using the "SAS General Linear Model Procedure (GLM)" with binding rate considered as dependent variable and animals, treatment, and stade (before or after treatment) as independent variables. A significative (p<0.01) difference was found between binding rates before and after the treatment in either the first or the second group. The two treatments were found to induce a significative (p<0.001) increase in binding rates when compared with values obtained before treatments. Even if all cows responded to treatments by a binding rate increase, the effect of the treatment differed significantly (p<0.01) from one cow to another which could be explained by a large individual variability. From this experiment, we conclude that production of eCG antibodies is a wide response in the cows herein presented and repeatedly submitted to high doses of eCG. This immune response appeared after three to five injections and binding rates remained elevated over weeks following the latest injection. Special care should be given to this active immunisation -that could explain refractoriness to treatments- if such repeated administrations high doses of eCG were applied in usual protocols. [less ▲]

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See detailRepeated intracoronary beta radiation for recurrent in-stent restenosis.
De Benedetti, E; Latchem, D; Roguelov, C et al

in Catheterization and Cardiovascular Interventions (2002), 55(2), 233-236

More than 70% of percutaneous coronary interventions are followed by a stent implantation. In-stent restenosis still occurs in 20-30% of patients and remains a therapeutic challenge. At present only ... [more ▼]

More than 70% of percutaneous coronary interventions are followed by a stent implantation. In-stent restenosis still occurs in 20-30% of patients and remains a therapeutic challenge. At present only vascular brachytherapy has been shown to be an effective treatment option. We report here one case of recurrent in-stent restenosis after vascular brachytherapy that was successfully treated by a second beta radiation treatment. Cathet Cardiovasc Intervent 2002;55:233–236. © 2002 Wiley-Liss, Inc. [less ▲]

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See detailRepeated thermal treatments applied to ordered TiO2 mesoporous thin film: Effect on the film crystallization and surface area
Henrist, Catherine ULg; Dubreuil, Olivier; Krins, Natacha ULg et al

Conference (2010, July 06)

Ordered, mesoporous films are prepared by template-assisted sol-gel techniques such as dip-coating from a precursors solution. However, monolayer films are only a few hundred nanometers thick and present ... [more ▼]

Ordered, mesoporous films are prepared by template-assisted sol-gel techniques such as dip-coating from a precursors solution. However, monolayer films are only a few hundred nanometers thick and present a limited surface area of active material resulting in poor photovoltaic performances. Therefore it is needed to increase the film thickness. A multilayer deposition process for anatase mesoporous film has been reported in the literature in 2005 by Zukalova and all. Unfortunately, later researches have shown a surface area limitation despite the increase of film thickness due to the repeated thermal treatments applied to the layers. In this study, we have investigated the microstructural evolution of a single mesoporous TiO2 layer submitted to repeated thermal treatments. The modifications are discussed in terms of film thickness, surface area, anatase crystals size and global crystallinity. Besides, we propose an alternative thermal treatment designed in an attempt to overcome the limitations induced by repeated calcinations. We have followed and compared the properties of mesoporous films submitted to both thermal treatments by X-ray diffraction (XRD), transmission electron microscopy (TEM) and environmental poroellipsometry (EEP). Those results show the importance of the tuning of thermal treatment when multilayers films are envisaged for DSSC applications. Indeed, this study quantifies the maximum perturbation encountered by the first layer during the preparation of a multilayer (up to 12) coating, which is submitted to a multistep calcination. Finally, the photovoltaic performances of assembled cells have been evaluated. [less ▲]

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See detailRepenser l'activité dans la maladie d'Alzheimer
Adam, Stéphane ULg

Conference (2011, October 21)

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See detailRepenser la 'puissance' mondiale au lendemain de la post-guerre froide
Wintgens, Sophie ULg; Mariage, Thibaud ULg

in Wintgens, Sophie (Ed.) La puissance : débat autour des jeux et enjeux du pouvoir (2012)

La prééminence de la conception réaliste a longtemps cadenassé le champ d’étude de la puissance en Relations internationales, aujourd’hui fortement contestée. L’analyse de l’émergence de «nouvelles ... [more ▼]

La prééminence de la conception réaliste a longtemps cadenassé le champ d’étude de la puissance en Relations internationales, aujourd’hui fortement contestée. L’analyse de l’émergence de «nouvelles puissances» est à ce titre riche d’enseignements. Afin de dépasser l’antagonisme classique entre les perspectives institutionnalistes et réalistes, cette introduction propose d’appréhender la puissance via une démarche alternative, à partir d’une approche hétérodoxe de l’hégémonie permettant d’entrevoir les phénomènes de domination insidieux et non ressentis comme tels. À l’instar de la Chine, engagée dans la construction d’un statut de puissance mondiale bardée d’un discours de légitimation aux accents tiers-mondistes (anti-hégémonisme, multipolarisation du monde, coopération Sud-Sud, etc.), l’accroissement de son influence mondiale ne dépend pas seulement de la disponibilité de ses ressources – matérielles et immatérielles –, ni de son aptitude à les mobiliser adéquatement (smart power). Elle tient également à l’image qu’elle se fait d’elle-même (auto-perception) et qu’elle cherche à véhiculer sur la scène internationale (représentation), ainsi qu’à la perception de son statut par les autres acteurs du système international (reconnaissance extérieure). La puissance de la Chine se mesure in fine à travers sa capacité à « s’affirmer comme une référence » pour ses pairs émergents, voire auprès des puissances occidentales. [less ▲]

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See detailRepenser la formation initiale, continue et l'accompagnement des professionnel(le)s
Pirard, Florence ULg; Camus, Pascale ULg

Conference given outside the academic context (2014)

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See detailRepenser la question de l'activité dans la maladie d'Alzheimer?
Adam, Stéphane ULg

Scientific conference (2011, October 14)

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See detailRepenser la sociologie du développement entre dynamiques du dedans et dynamiques du dehors. Une réflexion à partir du projet de société civile au Bénin
Pirotte, Gautier ULg

in Cahiers d'Etudes Africaines (2011), LI (2-3)(202-203), 473-490

Cet article formule un ensemble de réflexions visant à repenser une sociologie du développement centrée sur les acteurs et leurs pratiques, leurs représentations comme leurs identités ou leurs stratégies ... [more ▼]

Cet article formule un ensemble de réflexions visant à repenser une sociologie du développement centrée sur les acteurs et leurs pratiques, leurs représentations comme leurs identités ou leurs stratégies dans un souci de rééquilibrage analytique et méthodologique entre « développeurs » et « bénéficiaires » qui tienne compte des dynamiques du dedans comme du dehors et de leurs influences réciproques. Un renouvellement de la sociologie du développement requiert une attention plus fine aux interactions entre des acteurs différenciés (sur un plan économique, social, culturel, technologique et politique), qui , s’insérant dans des réseaux étendus et fluctuants, rendent possibles en termes simmelien la socialisation d’un contenu particulier, soit le « développement » décliné sous différents aspects ( de la lutte contre la pauvreté au projet de constitution de sociétés civiles en passant par des « petits projets » participatifs). Il nous faut donc, être attentif aux phénomènes d’inter-influence, aux processus de co-élaboration des pratiques et des discours qui participent à la mise en œuvre du développement et qui constituent sans doute l’objet fondamental d’une nouvelle sociologie du développement. [less ▲]

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See detailRepérage des données et des études - Synthèse bibliographique sur le logement (Wallonie-Lorraine-Luxembourg). Habitreg.net : un réseau pour répondre aux défis d'habiter sur des territoires ruraux et périurbains de Wallonie-Lorraine-Luxembourg
Halleux, Jean-Marie ULg; Strée, Julie ULg

Report (2011)

Le rapport est structuré en trois chapitres. Le premier porte sur les politiques d'aménagement et de logement au sein de la Wallonie, de la Lorraine et du Grand-Duché de Luxembourg. Le deuxième chapitre ... [more ▼]

Le rapport est structuré en trois chapitres. Le premier porte sur les politiques d'aménagement et de logement au sein de la Wallonie, de la Lorraine et du Grand-Duché de Luxembourg. Le deuxième chapitre est ensuite consacré aux caractéristiques des parcs de logemet lorrains et wallons. Le troisième chapitre est quant à lui consacré au sujet des évolutions socio-économiques et sociodémographiques. [less ▲]

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See detailRepérage scintigraphique préopératoire d'une métastase costale unique d'un adénocarcinome prostatique opéré.
Sanjurjo, Sylvia ULg; Hamida, Wissem; Letesson, Gaëtan et al

in Progrès en Urologie (2008), 18(6), 402-5

We present a case of a lonely bone lesion after a prostatic adenocarcinoma with recurrent increased PSA. The localization of the metastasis at the level of a rib is infrequent. The precise localization of ... [more ▼]

We present a case of a lonely bone lesion after a prostatic adenocarcinoma with recurrent increased PSA. The localization of the metastasis at the level of a rib is infrequent. The precise localization of the lesion was made possible by intraoperative scintigraphy. Histology confirmed the complete resection of the lesion with safe margins. [less ▲]

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See detailrépercussion sur la mortalité périnatale de la nouvelle classification par groupe de poids recommandée par l'OMS
Battisti, Oreste ULg; Langhendries, J. P.; Bertrand, J. M. et al

in Archives Belges de Médecine Sociale, Hygiène, Médecine du Travail et Médecine Légale = Belgisch Archief van Sociale Geneeskunde, Hygiene, Arbeidsgeneeskunde en Gerechtelijke Geneeskunde (1984), 42

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See detailRepercussions cardio-vasculaires des infections parodontales
Geerts, Sabine ULg; Legrand, Victor; Rompen, Eric ULg

Article for general public (2002)

De plus en plus de preuves s'accumulent montrant que les infections parodontales sont des facteurs de risque indépendants pour certaines pathologies systémiques dont les affections cardiovasculaires ... [more ▼]

De plus en plus de preuves s'accumulent montrant que les infections parodontales sont des facteurs de risque indépendants pour certaines pathologies systémiques dont les affections cardiovasculaires: fréquence de parodontite 2,6x plus grande chez les patients atteints d'ischémie cérébrales, risque de décès d'origine cardiovasculaire doublé en cas de parodontite chez des hommes de moins de 50 ans. [less ▲]

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See detailLes répercussions des hospitalisations psychiatriques sur l'accès aux soins de première ligne
Tellier, V; Gosset, Christiane ULg; de Froidmont, C et al

Conference (2005)

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