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See detailLes qualités d'une évaluation rigoureuse
Beckers, Jacqueline ULg; De Bal, Robert

in Cahiers Pédagogiques (1978), 162

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See detailQualités requises pour succéder
Moreau, Pierre ULg

in Moreau, Pierre (Ed.) Libéralités et successions (2012)

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See detailQuality Analysis Applied On Eddy Covariance Measurements At Complex Forest Sites Using Footprint Modelling
Rebmann, C.; Gockede, M.; Foken, T. et al

in Theoretical and Applied Climatology (2005), 80(2-4),

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See detailQuality and validation of numerical resolutions of unsteady flow equations for river networks used as a tool for water management
Pochet, Thierry; Pirotton, Michel ULg

in International Conference on Computation al Methods in Engineering (1992)

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See detailQuality assessment of GPS Integrated Precipitable Water Vapour Estimations using Water Vapour Radiometer Observations
Pottiaux, Eric; Warnant, René ULg

in Proceedings of the IAG General Assembly 2001 (2002)

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See detailQuality Assessment of Marketed Eggs in Basse kabylie (Algeria)
Moula, Nassim ULg; Ait Kaki, Asma ULg; Leroy, Pascal ULg et al

in Revista Brasileira de Ciência Avícola (2013), 15(4), 395-399

Quality variations in retail eggs are widely reported. This study aims at assessing the quality of eggs according to the marketing channel in the department of Bejaia (Algeria). In spring and summer 2012 ... [more ▼]

Quality variations in retail eggs are widely reported. This study aims at assessing the quality of eggs according to the marketing channel in the department of Bejaia (Algeria). In spring and summer 2012, 3330 eggs were bought in 30 stores divided into 3 categories: 10 supermarkets (1146 eggs), 10 public markets (1048 eggs), and 10 shops (1136 eggs). Egg weights differed significantly between marketing channels with 58.9±0.14, 61.2±0.13 and 62.8±0.13 g for public markets, shops and supermarkets, respectively (p<0.001). Although shell thickness was similar for all marketing channels, the proportion of damaged eggs was higher in public markets (9.0%), intermediate in food shops (7.3%) and lower in supermarkets (5.7%; p<0.05). The yolk/albumen ratio was significantly higher for eggs from supermarkets (48.0%) compared with the other channels (around 47.4%; p<0.05). The freshness of the eggs, measured by the Haugh method, was lower in public markets (74.3 units), intermediate in shops (77.6 units) and higher in supermarkets (79.9 units; p<0.05). The price of eggs, expressed in Algerian Dinar (AD) per kg, was significantly lower in public markets (124 AD/kg) compared with the two other channels (around 131 AD/kg; p<0.05). It is possible to conclude that egg quality in Bass Kabylie differs significantly among marketing channels, with higher quality observed in supermarkets. The lower quality of eggs in public markets is associated with lower price. Eggs from shops present an intermediate quality. A one-year study would allow studying both the potential seasonal effect and compare intrinsic variability across marketing channels. [less ▲]

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See detailQuality assessment of marketed eggs in Eastern Algeria
Kara Ali, Monira; Ait Kaki, Asma ULg; Milet, Asma et al

in Nature & Technologie (2014), 11(2), 52-58

The objective of this study was to compare eggs quality between industrial and local chickens in four departments of Eastern Algeria (Bejaia, Jijel, Mila and Setif). A total of 4748 eggs were bought from ... [more ▼]

The objective of this study was to compare eggs quality between industrial and local chickens in four departments of Eastern Algeria (Bejaia, Jijel, Mila and Setif). A total of 4748 eggs were bought from three marketing channels as following: shops (1184), public markets (2757) and supermarkets (807). The percentage of stained eggs was significantly different (P<0.001) between industrial (15.25%) and local eggs (27.61%). A significant difference (P<0.05) was observed between industrial and local egg weight (61.01 vs 53.28g), egg shell weight (7.10 vs 6.30g), albumen weight (37.44 vs 29.69g), albumen percentage (61.34 vs 55.71%), shell thickness (0.381 vs 0.325mm). However, yolk weight (6.10 vs 6.30g), yolk percentage (27.06 vs 32.44%), shell percentage (11.60 vs 11.89%), yolk/albumen ratio (0.44 vs 0.58), albumen height (5.27 vs 5.93mm), Haugh unit (69.12 vs 77.80), yolk color (9.52 vs 10.94) and egg price (7.67 vs 12.84DA) of local chicken were significantly (P<0.01) higher than in the case of industrial hen. Marketing channels affected significantly (P<0.01) egg weight, yolk weight, albumen weight, albumen height and price of a total studied eggs. Egg weight (59.03g) and egg price (10.87DA) from supermarkets were the highest. Eggs of local hens presented according to the national preference, interesting quality criteria such as freshness, yolk/albumen ratio and yolk color. [less ▲]

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See detailQUALITY ASSESSMENT OF MEDICINES MARKETED IN RWANDA, July-Oct. 2011
Habyalimana, Védaste; Mbinze Kindenge, Jérémie; Kadima Ntokamunda, Justin Léonard et al

Scientific conference (2012, July)

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See detailQuality Assessment of Polygonum cuspidatum and Polygonum multiflorum by 1H NMR Metabolite Fingerprinting and Profiling Analysis.
Frederich, Michel ULg; Wauters, Jean-Noël ULg; Tits, Monique ULg et al

in Planta Medica (2011), 77

The quality assessment and control of traditional Chinese medicines (TCM) nowadays receives a great deal of attention worldwide and particularly in Europe with its increasing local use. POLYGONUM ... [more ▼]

The quality assessment and control of traditional Chinese medicines (TCM) nowadays receives a great deal of attention worldwide and particularly in Europe with its increasing local use. POLYGONUM CUSPIDATUM Siebold & Zucc. and POLYGONUM MULTIFLORUM Thunb. are two members of the Polygonaceae family, which are widely used as Chinese medicinal plants. The aim of this study was to achieve an overview of the quality of P. CUSPIDATUM and P. MULTIFLORUM samples available on the Chinese market and to identify important metabolites for their discrimination, using (1)H NMR-based metabolomics. (1)H NMR and multivariate analysis techniques were applied to almost 60 plant samples collected in different places in China. Using (1)H NMR metabolomics, it was possible, without previous evaporation or separation steps, to obtain metabolic fingerprints to distinguish between the species. The important metabolites for discrimination were stilbene derivatives. Finally, a clear distinction between the two species was possible and the discriminant metabolites were identified. [less ▲]

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See detailQuality assessment of speckle patterns for digital image correlation
Lecompte, D.; Smits, A.; Bossuyt, Sven et al

in Optics & Lasers in Engineering (2006), 44(11), 1132-1145

Digital image correlation (DIC) is an optical–numerical full-field displacement measuring technique, which is nowadays widely used in the domain of experimental mechanics. The technique is based on a ... [more ▼]

Digital image correlation (DIC) is an optical–numerical full-field displacement measuring technique, which is nowadays widely used in the domain of experimental mechanics. The technique is based on a comparison between pictures taken during loading of an object. For an optimal use of the method, the object of interest has to be covered with painted speckles. In the present paper, a comparison is made between three different speckle patterns originated by the same reference speckle pattern. A method is presented for the determination of the speckle size distribution of the speckle patterns, using image morphology. The images of the speckle patterns are numerically deformed based on a finite element simulation. Subsequently, the displacements are measured with DIC-software and compared to the imposed ones. It is shown that the size of the speckles combined with the size of the used pixel subset clearly influences the accuracy of the measured displacements. [less ▲]

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See detailQuality assurance for prospective EORTC radiation oncology trials: The challenges of advanced technology in a multicenter international setting
Weber, D. C.; Poortmans, P. M. P.; Hurkmans, C. W. et al

in Radiotherapy & Oncology (2011), 100(1), 150-156

The European Organization for the Research and Treatment of Cancer (EORTC) is a pan-European structure charged with improving cancer treatment through the testing of new therapeutic strategies in phases I ... [more ▼]

The European Organization for the Research and Treatment of Cancer (EORTC) is a pan-European structure charged with improving cancer treatment through the testing of new therapeutic strategies in phases I-III clinical studies. Properly conducted trials in radiation oncology are required to demonstrate superiority of a new treatment over the current standard. The Radiation Oncology Group (ROG) has initiated a complex quality assurance (QA) program to ensure safe and effective treatment delivery. Most modern trials are multicenter and multidisciplinary, further increasing the importance of early, strict and consistent QA in radiotherapy (RT). QART measures confirm whether a site possesses minimum staff and equipment for participation. Dummy runs, reviews of patient treatment plans and complex dosimetry checks verify the ability of an institution to comply with the protocol. Data required for evaluation are increasingly exchanged digitally, allowing detailed plan reconstruction, evaluation of target volume delineation and recalculation of dose-volume parameters for comparison against predefined standards. The five tiers of QA implemented in EORTC trials are reviewed, along with past, current and future QART initiatives. As substantial human and financial resources are increasingly invested in QART, the importance of cost-benefit analysis of QA and its impact on clinical outcome cannot be overstated. © 2011 Elsevier Ltd. All rights reserved. [less ▲]

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See detailQuality assurance in quantitative microbial risk assessment
Boone, Idesbald; Van der Stede, Yves; Aerts, Marc et al

in Vlaams Diergeneeskundig Tijdschrift (2010), 79

Quantitative microbial risk assessment (QMRA) is being used to estimate the risk level of pathogens along the food chain and to support management decisions for the reduction of food-safety risks. The ... [more ▼]

Quantitative microbial risk assessment (QMRA) is being used to estimate the risk level of pathogens along the food chain and to support management decisions for the reduction of food-safety risks. The degree of credibility that can be attached to risk assessment results depends largely on the quality and quantity of the data, the model structure and the assumptions taken. Quality Assurance (QA) in QMRA is fulfilled when all steps in the QMRA process are technically and scientifically valid, so that it can meet its objectives. An overview of QA methods for QMRA is presented. Whereas sensitivity analysis and scenario analysis are common in QMRA, formal methods for the evaluation of data quality, the critical evaluation of assumptions, structured expert elicitation, the checklist approach, and peer review are rarely applied in QMRA but could largely improve the transparency in the results of QMRAs. The degree of implementation of these methods should be proportionate to the stakes of the risk management questions, and discussed in consultation between risk assessors and risk managers. [less ▲]

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See detailQuality assurance in repairing industrial floors: parameters and recommendations
Courard, Luc ULg; Bissonnette, Benoît

in Zajc, A.; Sustercic, J. (Eds.) Moznot Pocenitive Izvajanja Betonarskih Del (2011)

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete ... [more ▼]

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete structures is constantly increasing, and therefore repair or retrofitting requirements increase. Present concerns of sustainable development emphasizing repair or strengthening instead of new construction, acts as incentive to this trend. The bonded overlay technique is particularly suitable in the case of structures with large areas like industrial floors. This paper has the ambition to present reliable design methodology for the practitioner. Surface preparation, overlay design and material selection, application process and QC/QA are discussed and guidelines are proposed in order to enhance quality of repair operations. [less ▲]

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See detailQuality assurance in the 22991 EORTC ROG trial in localized prostate cancer: Dummy run and individual case review
Matzinger, O.; Poortmans, P.; Giraud, J.-Y. et al

in Radiotherapy & Oncology (2009), 90(3), 285-290

Introduction: EORTC trial 22991 was designed to evaluate the addition of concomitant and adjuvant short-term hormonal treatments to curative radiotherapy in terms of disease-free survival for patients ... [more ▼]

Introduction: EORTC trial 22991 was designed to evaluate the addition of concomitant and adjuvant short-term hormonal treatments to curative radiotherapy in terms of disease-free survival for patients with intermediate risk localized prostate cancer. In order to assess the compliance to the 3D conformal radiotherapy protocol guidelines, all participating centres were requested to participate in a dummy run procedure. An individual case review was performed for the largest recruiting centres as well. Materials and methods: CT-data of an eligible prostate cancer patient were sent to 30 centres including a description of the clinical case. The investigator was requested to delineate the volumes of interest and to perform treatment planning according to the protocol. Thereafter, the investigators of the 12 most actively recruiting centres were requested to provide data on five randomly selected patients for an individual case review. Results: Volume delineation varied significantly between investigators. Dose constraints for organs at risk (rectum, bladder, hips) were difficult to meet. In the individual case review, no major protocol deviations were observed, but a number of dose reporting problems were documented for centres using IMRT. Conclusions: Overall, results of this quality assurance program were satisfactory. The efficacy of the combination of a dummy run procedure with an individual case review is confirmed in this study, as none of the evaluated patient files harboured a major protocol deviation. Quality assurance remains a very important tool in radiotherapy to increase the reliability of the trial results. Special attention should be given when designing quality assurance programs for more complex irradiation techniques. © 2008 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailQuality assurance in the EORTC 22033-26033/CE5 phase III randomized trial for low grade glioma: The digital individual case review
Fairchild, A.; Weber, D. C.; Bar-Deroma, R. et al

in Radiotherapy & Oncology (2012), 103(3), 287-292

Introduction: The phase III EORTC 22033-26033/NCIC CE5 intergroup trial compares 50.4 Gy radiotherapy with up-front temozolomide in previously untreated low-grade glioma. We describe the digital EORTC ... [more ▼]

Introduction: The phase III EORTC 22033-26033/NCIC CE5 intergroup trial compares 50.4 Gy radiotherapy with up-front temozolomide in previously untreated low-grade glioma. We describe the digital EORTC individual case review (ICR) performed to evaluate protocol radiotherapy (RT) compliance. Methods: Fifty-eight institutions were asked to submit 1-2 randomly selected cases. Digital ICR datasets were uploaded to the EORTC server and accessed by three central reviewers. Twenty-seven parameters were analysed including volume delineation, treatment planning, organ at risk (OAR) dosimetry and verification. Consensus reviews were collated and summary statistics calculated. Results: Fifty-seven of seventy-two requested datasets from forty-eight institutions were technically usable. 31/57 received a major deviation for at least one section. Relocation accuracy was according to protocol in 45. Just over 30% had acceptable target volumes. OAR contours were missing in an average of 25% of cases. Up to one-third of those present were incorrectly drawn while dosimetry was largely protocol compliant. Beam energy was acceptable in 97% and 48 patients had per protocol beam arrangements. Conclusions: Digital RT plan submission and review within the EORTC 22033-26033 ICR provide a solid foundation for future quality assurance procedures. Strict evaluation resulted in overall grades of minor and major deviation for 37% and 32%, respectively. © 2012 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailQuality assurance of the EORTC 22043-30041 trial in post-operative radiotherapy in prostate cancer: Results of the Dummy Run procedure
Fenton, P. A.; Hurkmans, C.; GULYBAN, Akos ULg et al

in Radiotherapy & Oncology (2013)

Background and purpose: The EORTC 22043-30041 trial investigates the role of the addition of androgen suppression to post-operative radiotherapy in patients who have undergone radical prostatectomy. As ... [more ▼]

Background and purpose: The EORTC 22043-30041 trial investigates the role of the addition of androgen suppression to post-operative radiotherapy in patients who have undergone radical prostatectomy. As part of the quality assurance of radiotherapy (QART) a Dummy Run (DR) procedure was performed. Materials and method: The protocol included detailed and published delineation guidelines. Participating institutions digitally submitted radiotherapy treatment volumes and a treatment plan for a standard clinical case. Submissions were centrally reviewed using the VODCA software platform. Results: Thirty-eight submissions from thirty-one institutions were reviewed. Six were accepted without comments. Twenty-three were accepted with comments on one or more items: target volume delineation (22), OAR delineation (23), planning and dosimetry (3) or treatment verification (1). Nine submissions were rejected requiring resubmission, seven for target volume delineation reasons alone. Intervention to highlight the importance of delineation guidelines was made prior to the entry of the first patient in the trial. After this, a lower percentage of resubmissions was required. Conclusions: The EORTC 22043-30041 Dummy Run highlights the need for timely and effective QART in clinical trials. The variation in target volume and OAR definition demonstrates that clinical guidelines and radiotherapy protocols are not a substitute for QART procedures. Early intervention in response to the Dummy Run improved protocol understanding. © 2013 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailQuality assurance: experience of an university
Chapelle, Jean-Paul ULg

Conference (2000, September 26)

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See detailQuality by design compliant analytical method validation
Rozet, Eric ULg; Ziemons, Eric ULg; Marini Djang'Eing'A, Roland ULg et al

in Analytical Chemistry (2012), 84

The concept of quality by design (QbD) has recently been adopted for the development of pharmaceutical processes to ensure a predefined product quality. Focus on applying the QbD concept to analytical ... [more ▼]

The concept of quality by design (QbD) has recently been adopted for the development of pharmaceutical processes to ensure a predefined product quality. Focus on applying the QbD concept to analytical methods has increased as it is fully integrated within pharmaceutical processes and especially in the process control strategy. In addition, there is the need to switch from the traditional checklist implementation of method validation requirements to a method validation approach that should provide a high level of assurance of method reliability in order to adequately measure the Critical Quality Attributes (CQAs) of the drug product. The intended purpose of analytical methods is directly related to the final decision that will be made with the results generated by these methods under study. The final aim for quantitative impurity assays is to correctly declare a substance or a product as compliant with respect to the corresponding product specifications. For content assays, the aim is similar: making the correct decision about product compliance with respect to their specification limits. It is for these reasons that the fitness of these methods should be defined, as they are key elements of the Analytical Target Profile (ATP). Therefore, validation criteria, corresponding acceptance limits and method validation decision approaches should be settled in accordance with the final use of these analytical procedures. This work proposes a general methodology to achieve this in order to align method validation within the QbD framework and philosophy. β-expectation tolerance intervals are implemented to decide about the validity of analytical methods. The proposed methodology is also applied to the validation of analytical procedures dedicated to the quantification of impurities or active product ingredients (API) in drug substances or drug products and its applicability is illustrated with two case studies. [less ▲]

Detailed reference viewed: 179 (21 ULg)