Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
See detailMulti‐scale modelling of fibre reinforced composite with non‐local damage variable
Wu, Ling ULg; Noels, Ludovic ULg; Adam, Laurent et al

Conference (2011, July)

Classical finite element simulations face the problems of losing uniqueness and strain localization when the strain softening of materials is involved. Thus, when using continuum damage model or ... [more ▼]

Classical finite element simulations face the problems of losing uniqueness and strain localization when the strain softening of materials is involved. Thus, when using continuum damage model or plasticity softening model, numerical convergence will not be obtained with the refinement of the finite element discretization when strain localization occurs. Gradient-enhanced softening and non-local continua models have been proposed by several researchers in order to solve this problem. In such approaches, the spatial gradients of state variables are incorporated in the macroscopic constitutive equation [1, 2]. However, when dealing with complex heterogeneous materials, a direct simulation of the macroscopic structures is unreachable, motivating the development of non-local homogenization schemes [3]. In our work, a gradient-enhanced homogenization procedure is proposed for fiber reinforced materials. In the approach, the fiber is assumed to remain linear elastic while the matrix material is modeled as elasto-plastic [4] coupled with damage and is described by a non-local constitutive model [5]. Toward this end, the mean-field homogenization is based on the knowledge of the macroscopic deformation tensors, internal variables and their gradients, which are applied to a micro-structural representative volume element (RVE). Macro-stress is then obtained from a homogenization process. This procedure is applied to simulate damage process occurring in unidirectional carbon-fiber reinforced epoxy composites submitted to different loading histories. [less ▲]

Detailed reference viewed: 61 (4 ULg)
See detailMulti‐spectral simultaneous observations of Saturn's aurorae in Jan. 2009
Lamy, L.; Prange, R.; Gustin, Jacques ULg et al

Conference (2012)

Detailed reference viewed: 11 (3 ULg)
Full Text
Peer Reviewed
See detailMulty-year cycles observed in air temperature data and proxy series
Mabille, Georges ULg; Nicolay, Samuel ULg

in European Physical Journal. Special Topics (2009), 174

First, palaeoclimatic time series are analyzed under the lens of the continuous wavelet transform. Two cycles, of period 30 and 43 months respectively, are detected in millennial temperature ... [more ▼]

First, palaeoclimatic time series are analyzed under the lens of the continuous wavelet transform. Two cycles, of period 30 and 43 months respectively, are detected in millennial temperature reconstructions. These rhythms correspond to the ones detected in weather station temperature records in a previous study of the authors. It is then showed that most parts of the globe are affected by at least one of the two cycles. Their relationship with the main climatic indices is also investigated, as well as the statistical significance of the observations. [less ▲]

Detailed reference viewed: 26 (9 ULg)
See detailEl mundo sobre el papel. El impacto de la escritura y la lectura en la estructura del conocimiento
Olson, David R.; Willson, Patricia ULg

Book published by Editorial Gedisa (1999)

Detailed reference viewed: 1185 (2 ULg)
Full Text
See detailMUNE in the last 30 years: what can we expect of it in practice?
WANG, François-Charles ULg; GERARD, Pascale ULg; BOUQUIAUX, Olivier ULg

in Correspondances en Nerf & Muscle (2004)

Detailed reference viewed: 14 (4 ULg)
Full Text
See detailMUNIX
WANG, François-Charles ULg

Conference (2015, March 06)

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailMunkoyo : des racines comme sources potentielles en enzymes amylolytiques et une boisson fermentée traditionnelle (synthèse bibliographique)
Foma, Roland Kibwega; Destain, Jacqueline ULg; Kayisu, Kalenga et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2013), 17(2), 352-363

Detailed reference viewed: 38 (6 ULg)
Full Text
See detailLe Munkoyo : une source d'amylases végétales pour une boisson fermentée traditionnelle
Foma Kibwega, Roland ULg

Doctoral thesis (2013)

In Africa, several sources of amylases are not well documented. Munkoyo roots are used as the source of amylases during the traditional preparation of a fermented beverage called munkoyo. These roots are ... [more ▼]

In Africa, several sources of amylases are not well documented. Munkoyo roots are used as the source of amylases during the traditional preparation of a fermented beverage called munkoyo. These roots are unique as the synthesis and accumulation of amylases activities do not require germination. Despite this advantage, munkoyo roots are not well known as sources of amylases and they have not yet been introduced into industrial processes. Thus, the aim of this PhD project was to (1) promote munkoyo roots as sources of α- and β-amylases and to (2) propose pathways of optimization and industrialization of manufacturing munkoyo beverage. In the first part, purification, characterization and identification of α- and β-amylases from munkoyo roots was achieved. Amylases from roots of Eminia holubii, Eminia harmsiana, Rhynchosia insignis insignis and Rhynchosia insignis affinis were retained in our study. Compared to malted cereals, α- and β-amylases from munkoyo roots are more thermostable and their activities are optimal at high temperatures. However, these properties are closer to those of germinated cotyledons belonging to some Fabaceae family plants. Using LC-ESI MSMS analysis, this study showed significant matching of α- and β-amylases from munkoyo roots to germinated leguminous seeds. In the second part, the traditional production of munkoyo beverage was studied. The evolution of physicochemical parameters and ferments involved in spontaneous fermentation was investigated. Acidification is promoted by thermophilic and heterofermentative lactic acid bacteria. Alcohol production in munkoyo is due mainly to Saccharomyces cerevisiae. The study shows that knowledge of amylase properties and the use of an appropriate microbial starter will optimize the manufacturing process and the quality of munkoyo beverage. [less ▲]

Detailed reference viewed: 125 (23 ULg)
Full Text
See detailMuñoz et Sampayo vus par...
Dejasse, Erwin ULg

in Fofi, Goffredo (Ed.) Conversations avec Muñoz & Sampayo (2008)

Interviews with comic artist about José Muñoz and Carlos Sampayo

Detailed reference viewed: 76 (4 ULg)
See detailLe mur d'enceinte du temple d'Amon-Rê à Karnak
Winand, Jean ULg

Scientific conference (2005, November 17)

Detailed reference viewed: 27 (0 ULg)
Peer Reviewed
See detailLe mur dans l'art et l'archéologie
Duchesne, Jean-Patrick ULg

in Art&fact (1985), 4

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailLe Mur et le masque. À propos de Banksy.
Saint-Amand, Denis ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (in press)

Detailed reference viewed: 85 (11 ULg)
See detailMurdering the Text: Genre and Gender Issues in Margaret Atwood's Recent Short Short Fiction
Delville, Michel ULg

in Ledent, Bénédicte (Ed.) The Contact and the Culmination: Essays in Honour of Hena Maes-Jelinek (1997)

Detailed reference viewed: 167 (3 ULg)
Full Text
Peer Reviewed
See detailThe murid herpesvirus-4 gH/gL binds to glycosaminoglycans.
Gillet, Laurent ULg; Colaco, Susanna; Stevenson, Philip G

in PLoS ONE (2008), 3(2), 1669

The first contact a virus makes with cells is an important determinant of its tropism. Murid Herpesvirus-4 (MuHV-4) is highly dependent on glycosaminoglycans (GAGs) for cell binding. Its first contact is ... [more ▼]

The first contact a virus makes with cells is an important determinant of its tropism. Murid Herpesvirus-4 (MuHV-4) is highly dependent on glycosaminoglycans (GAGs) for cell binding. Its first contact is therefore likely to involve a GAG-binding virion glycoprotein. We have previously identified two such proteins, gp70 and gp150. Gp70 binds strongly to GAGs. However, deleting it makes little difference to MuHV-4 cell binding or GAG-dependence. Deleting gp150, by contrast, frees MuHV-4 from GAG dependence. This implies that GAGs normally displace gp150 to allow GAG-independent cell binding. But the gp150 GAG interaction is weak, and so would seem unlikely to make an effective first contact. Since neither gp70 nor gp150 matches the expected profile of a first contact glycoprotein, our understanding of MuHV-4 GAG interactions must be incomplete. Here we relate the seemingly disconnected gp70 and gp150 GAG interactions by showing that the MuHV-4 gH/gL also binds to GAGs. gH/gL-blocking and gp70-blocking antibodies individually had little effect on cell binding, but together were strongly inhibitory. Thus, there was redundancy in GAG binding between gp70 and gH/gL. Gp150-deficient MuHV-4 largely resisted blocks to gp70 and gH/gL binding, consistent with its GAG independence. The failure of wild-type MuHV-4 to do the same argues that gp150 is normally engaged only down-stream of gp70 or gH/gL. MuHV-4 GAG dependence is consequently two-fold: gp70 or gH/gL binding provides virions with a vital first foothold, and gp150 is then engaged to reveal GAG-independent binding. [less ▲]

Detailed reference viewed: 44 (15 ULg)
Full Text
Peer Reviewed
See detailThe Murid Herpesvirus-4 gL regulates an entry-associated conformation change in gH.
Gillet, Laurent ULg; Colaco, Susanna; Stevenson, Philip G

in PLoS ONE (2008), 3(7), 2811

The glycoprotein H (gH)/gL heterodimer is crucial for herpesvirus membrane fusion. Yet how it functions is not well understood. The Murid Herpesvirus-4 gH, like that of other herpesviruses, adopts its ... [more ▼]

The glycoprotein H (gH)/gL heterodimer is crucial for herpesvirus membrane fusion. Yet how it functions is not well understood. The Murid Herpesvirus-4 gH, like that of other herpesviruses, adopts its normal virion conformation by associating with gL. However, gH switched back to a gL-independent conformation after virion endocytosis. This switch coincided with a conformation switch in gB and with capsid release. Virions lacking gL constitutively expressed the down-stream form of gH, prematurely switched gB to its down-stream form, and showed premature capsid release with poor infectivity. These data argue that gL plays a key role in regulating a gH and gB functional switch from cell binding to membrane fusion. [less ▲]

Detailed reference viewed: 15 (3 ULg)
Full Text
Peer Reviewed
See detailMurine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo
Van Valckenborgh, E.; De Raeve, H.; Devy, L. et al

in British Journal of Cancer (2002), 86(5), 796-802

Multiple myeloma is a B cell malignancy. Recently, it has been demonstrated that bone marrow samples of patients with multiple myeloma display an enhanced angiogenesis. The mechanisms involved seem to be ... [more ▼]

Multiple myeloma is a B cell malignancy. Recently, it has been demonstrated that bone marrow samples of patients with multiple myeloma display an enhanced angiogenesis. The mechanisms involved seem to be multiple and complex. We here demonstrate that the murine 5T multiple myeloma models are able to induce angiogenesis in vitro by using a rat aortic ring assay and in vivo by determining the microvessel density. The rat aortic rings cultured in 5T multiple myeloma conditioned medium exhibit a higher number of longer and more branched microvessels than the rings cultured in control medium. In bone marrow samples from 5T multiple myeloma diseased mice, a statistically significant increase of the microvessel density was observed when compared to bone marrow samples from age-matched controls. The angiogenic phenotype of both 5T multiple myeloma cells could be related, at least in part, to their capacity to produce vascular endothelial growth factor. These data clearly demonstrate that the 5T multiple myeloma models are good models to study angiogenesis in multiple myeloma and will allow to unravel the mechanisms of neovascularisation, as well as to test new putative inhibitors of angiogenesis. [less ▲]

Detailed reference viewed: 18 (4 ULg)
Full Text
Peer Reviewed
See detailMurine bone marrow stromal cells sustain in vivo the survival of hematopoietic stem cells and the granulopoietic differentiation of more mature progenitors.
Hubin, Frederique; Humblet, Chantal ULg; Belaid, Zakia ULg et al

in Stem Cells (2005), 23(10), 1626-33

The study of the human hematopoietic system would be facilitated by availability of a relevant animal model. Because the medullar microenvironment is made of different types of cells, interactions between ... [more ▼]

The study of the human hematopoietic system would be facilitated by availability of a relevant animal model. Because the medullar microenvironment is made of different types of cells, interactions between hematopoietic cells and stromal cells are difficult to analyze in detail. As an approach for establishing an in vivo model to dissect these interactions, we grafted murine bone marrow fibroblastic cells (MS-5 cell line) with hematopoietic cells into the kidney capsule of syngenic mice. To identify the origin of cells present in the graft, we used green fluorescent protein-stable transfected MS-5 cells for the transplantation. To analyze the evolution of stromal cells and identify hematopoietic cells able to develop in these conditions, we performed morphology, histochemistry, and immunohistology on tissue sections at different times after transplantation. When injected alone, MS-5 cells differentiate into adipocytes. When injected with a bone marrow suspension or with isolated CD45+ cells (leukocytes), the stromal cells keep their fibroblastic morphology and their alkaline phosphatase expression and sustain granulopoiesis. When injected with hematopoietic stem cells called c-kit+ Sca-1+ Lin- suspension, clusters of hematopoietic cells are also observed: They do not present any granulopoietic activity and do not belong to B or T population nor to erythroid lineage. They are quiescent, induce bone marrow recovery and survival of lethally irradiated recipients, are able to form macroscopic colonies in the spleen, and are able to form very few colonies in vitro, suggesting that they are hematopoietic stem cells. In conclusion, our results show that reticular fibroblastic stromal cells MS-5 sustain the survival of stem cells and are not able to induce their differentiation. However, they can control differentiation, proliferation, and/or survival of hematopoietic cells engaged in myeloid lineage. [less ▲]

Detailed reference viewed: 65 (6 ULg)