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Peer Reviewed
See detailPotential paleoseismological records in the Western Gulf of Corinth sediments (Greece) for the last 500 years
Beckers, Arnaud ULg; Mortier, Clément; Beck, Christian et al

Conference (2013, November 06)

Related to the Gulf of Corinth rifting, five earthquakes of magnitude greater than 5.8 occurred in the last 35 years. Consequently, the question of earthquake (EQ) hazard is particularly relevant. Onland ... [more ▼]

Related to the Gulf of Corinth rifting, five earthquakes of magnitude greater than 5.8 occurred in the last 35 years. Consequently, the question of earthquake (EQ) hazard is particularly relevant. Onland paleoseismological data are scarce and offshore data were absent before the present study. We investigated recent sediments bounding three well-defined major seismogenic faults: Aegion, Trizonia and Psathopyrgos faults. We retrieved 12 gravity cores from 50 to 85 cm long in three distinct sites: the southern shelf (40 to 50 m deep), a 180 m deep sub-basin, and a transect from the southern coast to the center of the gulf. Chronology is based on 137Cs (Atmospheric Nuclear Experiments) and 210Pb decay for two sites (Aegion and Trizonia). Considering sedimentation rates estimates in these areas, the longer cores record about 500 years of sedimentary archives. We performed granulometry, magnetic susceptibility, loss on ignition and geochemical (X-Ray Fluorescence) measurements on cores from each site. Some samples were observed with a binocular to identify the nature of the grains. We sought to identify layers potentially attributed to EQ-related processes like liquefaction and tsunamis for the sites on the shelves or mass transport and turbidity currents for the basins. In Aegion, 3 coarser layers have been identified at identical depth in 3 cores across the scarp. 210Pb decay show erosion just under the first event, that we attributed to the 1995 tsunami (backwash deposit) (figure). In the Trizonia Sub-Basin, among 3 clear grain-size peaks, two have been attributed to the 1817 Aegion EQ and the 1660 Galaxidi EQ. In Psathopyrgos, 10 “events” (grain-size and Zr/Rb peaks) have been identified in the deepest part of the transect and at least 2 on the shelf. Their analysis is in progress. [less ▲]

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See detailPotential Physical And Chemical Barriers To Infection By The Burrowing Nematode Radopholus Similis In Roots Of Susceptible And Resistant Banana (Musa Spp.)
Wuyts, Nathalie; Lognay, Georges ULg; Verscheure, Marjolaine et al

in Plant Pathology (2007), 56(5), 878-890

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See detailPotential Proteomic Biomarkers Associated To Mucosal Healing In Crohn’s Disease
MEUWIS, Marie-Alice ULg; Baiwir, Dominique ULg; Mazzucchelli, Gabriel ULg et al

Poster (2014, October 06)

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated ... [more ▼]

Introduction and objectives: In Crohn's disease (CD), there is a discrepancy between clinical activity of the disease (symptoms) and intestinal healing. However absence of tissue healing is associated with the risk of relapse and tissue damage progression. Endoscopy is costly and invasive. Hence biomarkers correlating with intestinal healing could improve disease management. We aimed to identify potential biomarkers associated to CD mucosal healing by a shotgun proteomics label free study. Methods: We used the STORI clinical trial cohort (n=103) aiming at identifying markers associated to relapse prediction after Infliximab treatment withdrawals. We used serum samples of patients in clinical remission, grouped according to the degree of intestinal healing seen at endoscopy. We performed depletion of the 20 most abundant plasma proteins on each serum pools and ran a proteomics label free differential analysis using 2D-nanoUPLC-MSE HDMS Synapt G1 for data acquisition and Protein Lynks Global Server vs 2.4 for data analysis (Waters, Corp., Milford, USA). Results and Discussion: We obtained potential biomarkers and designed a multiplexed -selected reaction monitoring (SRM) method for validation of these candidates in each individual patient. The method may also be tested in an independent set of IBD patients with and without mucosal healing. Conclusions: This research strategy and results of SRM validation of potential biomarkers associated to mucosal healing in this cohort of CD patients as well as the tests done on other CD patients, may provide new opportunities for CD follow-up tests development. [less ▲]

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See detailPotential research on marine mammals
Jauniaux, Thierry ULg; Coignoul, Freddy ULg

in Animal inside and outside the laboratory (2010)

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See detailA potential role for bat tail membranes in flight control
Gardiner, James D; Dimitriadis, Grigorios ULg; Codd, Jonathan R et al

in PLoS ONE (2011), 6(3), 18214

Wind tunnel tests conducted on a model based on the long-eared bat Plecotus auritus, indicated that the position of the tail membrane (uropatagium) can significantly influence flight control. Adjusting ... [more ▼]

Wind tunnel tests conducted on a model based on the long-eared bat Plecotus auritus, indicated that the position of the tail membrane (uropatagium) can significantly influence flight control. Adjusting tail position by increasing the angle of the legs relative to the body, has a two-fold effect; increasing leg-induced wing camber (i.e. locally increased camber and angle of attack of the inner wing surface) and increasing the angle of attack of the tail membrane. We also used our model to examine the effects of flying with and without a tail membrane. For the bat model with a tail membrane increasing leg angle increased the lift, drag and nose-down pitching moment produced. However, removing the tail membrane significantly reduced the change in pitching moment with increasing leg angle, but it had a much smaller effect on the level of lift and drag produced. The tail membrane, therefore, is potentially important for controlling the level of pitching moment produced by bats and an aid to flight control, specifically improving agility and manoeuvrability. Although the tail of bats is different from that of birds, in that it is only divided from the wings by the legs, it nonetheless, may, in addition to its prey capturing function, fulfil a similar role in aiding flight control. [less ▲]

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See detailPotential role of Alternaria and Cladosporium species in canine lymphoplasmacytic rhinitis
Mercier, Elise ULg; Peters, I.R.; Billen, Frédéric ULg et al

in Journal of Small Animal Practice (2013), 54 (4)

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See detailPotential Therapeutic Target Discovery by 2D-DIGE Proteomic Analysis in Mouse Models of Asthma
QUESADA CALVO, Florence ULg; Fillet, Marianne ULg; Renaut, Jenny et al

in Journal of Proteome Research (2011), 10(9), 4291-4301

As asthma physiopathology is complex and not fully understood to date; it is expected that new key mediators are still to be unveiled in this disease. The main objective of this study was to discover ... [more ▼]

As asthma physiopathology is complex and not fully understood to date; it is expected that new key mediators are still to be unveiled in this disease. The main objective of this study was to discover potential new target proteins with a molecular weight >20 kDa by using two-dimensional differential in-gel electrophoresis (2D-DIGE) on lung parenchyma extracts from control or allergen-exposed mice (ovalbumin). Two different mouse models leading to the development of acute airway inflammation (5 days allergen exposure) and airway remodeling (10 weeks allergen exposure) were used. This experimental setting allowed the discrimination of 33 protein spots in the acute inflammation model and 31 spots in the remodeling model displaying a differential expression. Several proteins were then identified by MALDI-TOF/TOF MS. Among those differentially expressed proteins, PDIA6, GRP78, Annexin A6, hnRPA3, and Enolase display an increased expression in lung parenchyma from mice exposed to allergen for 5 days. Conversely, Apolipoprotein A1 was shown to be decreased after allergen exposure in the same model. Analysis on lung parenchyma of mice exposed to allergens for 10 weeks showed decreased calreticulin levels. Changes in the levels of those different mediators were confirmed by Western blot and immunohistochemical analysis. Interestingly, alveolar macrophages isolated from lungs in the acute inflammation model displayed enhanced levels of GRP78. Moreover, intratracheal instillation of anti-GRP78 siRNA in allergen-exposed animals led to a decrease in eosinophilic inflammation and bronchial hyperresponsiveness. This study unveils new mediators of potential importance that are up- and down-regulated in asthma. Among up-regulated mediators, GRP-78 appears as a potential new therapeutic target worthy of further investigations. [less ▲]

Detailed reference viewed: 64 (19 ULg)
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See detailPotential use of GFP microbial biosensors for the detection of mixing imperfections and cell viability in bioreactors
Delvigne, Frank ULg; Delafosse, Angélique ULg; Collignon, Marie-Laure ULg et al

Conference (2011, September 25)

The dynamics of microbial stress response in intensive cultivation conditions remains misunderstood. In this work, two green fluorescent protein (GFP) transcriptional reporters have been used as ... [more ▼]

The dynamics of microbial stress response in intensive cultivation conditions remains misunderstood. In this work, two green fluorescent protein (GFP) transcriptional reporters have been used as biosensors of the heterogeneities generated in a two-compartment scale-down reactor. The stress promoters have been chosen for their responsiveness to carbon limitation corresponding to the global substrate profiles encountered in intensive fed-batch cultures. From our results, it can be concluded that the exposure of microbial cells to substrates heterogeneities tends to decrease the GFP expression level in fed-batch mode. Fluorescence intensities have been monitored at the single cell level by using flow cytometry. During the course of the fed-batch culture, a drop at the level of the intracellular GFP content has been observed for the two scale-down operating conditions and for the two promoters sensitive to substrate limitation (rpoS and csiE). The fluorescence drop can be attributed to the repression of these promoters but also to the release of GFP to the extracellular medium according to the increase of the fluorescence level of the supernatant. This leakage has been observed for all the operating conditions, i.e. the scale-down reactors and the culture operating in the normal mode. Interestingly, GFP leakage is more pronounced in the case of the cultures operated in the normal mode. Indeed, staining by propidium iodide (PI) tends to be more elevated for the microbial cells cultured under the normal mode by comparison with those cultured in scale-down conditions, indicating a higher permeability of the membrane. These results are in accordance with previously published ones (Hewitt and co-workers) suggesting that microbial cells cultivated in heterogeneous bioreactors (scale-down and large-scale bioreactors) exhibits a higher viability level. These results suggest that GFP microbial biosensors could be used to detect simultaneously mixing imperfections and their impact on the viability of microorganisms. [less ▲]

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See detailPotential use of micro-array technology (bio-puce) in the diagnosis of inflammatory disorders in the horse
Lekeux, Pierre ULg; Thomas, A.; Ramery, Eve ULg et al

in XVII. Tagung über Pferdekrankheiten im Rahmen der EQUITANA (2007)

Detailed reference viewed: 54 (13 ULg)
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See detailPotential use of mid-infrared milk spectrum in pregnancy diagnosis of dairy cows
Laine, Aurélie ULg; Goubau, Amaury; Dale, Laura-Monica et al

in Book of Abstracts of the 64th Annual Meeting of the European Federation of Animal Science (2013)

Detailed reference viewed: 58 (41 ULg)
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See detailPotential use of mid-infrared milk spectrum in pregnancy diagnosis of dairy cows
Laine, Aurélie ULg; Goubau, Amaury; Dale, Laura-Monica et al

Conference (2013)

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See detailPotential use of milk mid-infrared spectra to predict individual methane emission of dairy cows
Dehareng, Frédéric; Delfosse, Camille; Froidmont, Eric et al

in Animal (2012), 6(10), 1694-1701

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See detailTHE POTENTIAL USE OF NEAR-INFRARED SPECTROSCOPY FOR THE QUALITY ASSESSMENT OF EGGS AND EGG PRODUCTS
GALIŞ, Anca; Dale, Laura ULg; Boudry, Christelle ULg et al

in Scientific Works. C Series. Veterinary Medicine (2012), LVIII(3), 294-307

In a context of high productivity, eggs’ quality assessment is necessary for enhanced safety and quality assurance towards the consumers and feedback for producers. The quality assessment of eggs and egg ... [more ▼]

In a context of high productivity, eggs’ quality assessment is necessary for enhanced safety and quality assurance towards the consumers and feedback for producers. The quality assessment of eggs and egg products is performed using destructive and time-consuming methods, therefore the use of rapid tools becomes mandatory, especially in the case of a high production rate. Near Infrared (NIR) spectroscopy is considered a very reliable and rapid technique with large use in food industry. At the farm level, NIR spectroscopy technique would be an interesting tool to determine the chemical and physical properties of eggs, eggshell and internal quality and, moreover, this information may help the layer farm manager when a problem occurs in the flock. Its application in the egg industry is aimed at the quality changes in eggs during storage and quality assessment of the egg products, through the compositional analysis. It is possible and in some cases successful the prediction and/or determination of different parameters such as: protein, total lipid and total solids content (for liquid egg products), polyunsaturated fatty acids (for freeze-dried egg yolk), moisture, fat and protein content (for spray-dried whole eggs). In addition, for the white colored shell eggs, the detection of blood and meat spots is also successful. Further studies with NIR and near infrared hyper spectral imaging system (NIR-HSI) are needed in this direction, as the results obtained until now are very promising for the development of a rapid tool for quality assessment of eggs and egg products. [less ▲]

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See detailPotential use of Paracentrotus lividus as bioindicator for recent trace element pollution monitoring
Richir, Jonathan ULg; Gobert, Sylvie ULg; Bouquegneau, Jean-Marie ULg

Poster (2008, October)

The Mediterranean Sea is an enclosed basin, highly submitted to anthropogenic pressures. Chemical pollution originating from coastal urban centres and industries, or carried by air and rivers, will ... [more ▼]

The Mediterranean Sea is an enclosed basin, highly submitted to anthropogenic pressures. Chemical pollution originating from coastal urban centres and industries, or carried by air and rivers, will primarily affect its coastal ecosystems. The pollution by trace elements into the marine environment is rapidly evolving further to the recent modifications of their production and industrial uses by men. As a result, some trace elements that were previously poorly studied can be considered now as environmental pollutants, whose concentrations can sometimes be way above their natural baseline levels. The purple sea urchin Paracentrotus lividus is a well know bioindicator used for metal pollution monitoring (Fe, Cd, Cr, Pb, Zn and Cu) along the Mediterranean and Atlantic coasts. This sedentary organism successfully concentrates the pollutants diluted in its environment, and the measured concentrations reflect properly the health status of the ecosystem. This study is a first approach on the use of P. lividus as bioindicator for some less investigated trace elements (Al, V, Mn, Co, Ni, Se, Mo and Ag), chosen for their potential toxic effects. We have compared the element concentrations of the digestive tract tissues and gonads of female and male sea urchins. The organisms were frozen prior to dissection, or they were dissected alive, the two experimental procedures being compared afterwards. The existence of an eventual relationship between their gonadic index or their test diameter and the measured pollutant concentrations was also investigated. [less ▲]

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See detailPotential valorization for the finest particles of Automotive Shredder Residue (ASR) as filler in bituminous concrete
Bareel, Pierre-Francois; Courard, Luc ULg; Bastin, David ULg et al

in Proceedings of REWAS'04 - Global Symposium on Recycling, Waste Treatment and Clean Technology (2004)

Car manufacturers are faced with increasingly severe European regulations concerning End of Live Vehicles (ELV) recycling. Issues for the coarse fractions of Automotive Shredder Residue (ASR) are now ... [more ▼]

Car manufacturers are faced with increasingly severe European regulations concerning End of Live Vehicles (ELV) recycling. Issues for the coarse fractions of Automotive Shredder Residue (ASR) are now quite largely studied. However, the European objectives could only be achieved by considering the processing and valorization of the fine ASR fraction (< 2mm) which usually represents 5 to 10 wt.% of shredded ELV. A laboratory study was carried out on the fine ASR fraction. By combining granulometric, gravimetric and magnetic separations, four valorizable fractions were identified. This paper presents the valorization of the finest fraction (< 250 μm) as filler in bituminous concrete. Physical and chemical properties were first determined. Bituminous concrete samples were then prepared with different substitution levels of calcareous filler by fine ASR. Marshall tests (mechanical properties) and leaching tests were performed without compromising results. [less ▲]

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See detailPotential valorization for the finest particles of Automotive Shredder Residues
Bareel, Pierre-François; Mordant, Bruno; Bastin, David ULg et al

in Acta Metallurgica Slovaca (2004), 2

Detailed reference viewed: 17 (2 ULg)
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See detailPotential valorization of the fine light fraction of automotive shredder residues (ASR)
Bareel, Pierre-François; Bastin, David ULg; Frenay, Jean ULg

in Proceedings of the International Symposium of Metals and Energy Recovery (2003)

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See detailPotential-dependent structure of the interfacial water on the gold electrode
Nihonyanagi, Satoshi; Ye, Shen; Uosaki, Kohei et al

in Surface Science (2004), 573

Doubly tunable sum frequency generation (SFG) spectra demonstrate that the water molecules at gold/electrolyte interface change their orientation with applied potential. At negative potentials, water ... [more ▼]

Doubly tunable sum frequency generation (SFG) spectra demonstrate that the water molecules at gold/electrolyte interface change their orientation with applied potential. At negative potentials, water molecules in the double layer align with their oxygen atom pointing to the solution. As potential became positive to be close to the potential of zero charge (PZC), the SFG signal decreased, suggesting the OH groups of the water molecule are either in random orientation or parallel to the electrode. As potential became more positive than the PZC, the SFG signal increased again with the oxygen-up orientation as same as in the negative potential region, indicating that water molecules interact with the adsorbed sulfate anions. The peak position of the SFG spectra indicates a relatively disordered state of water molecules at the gold electrode surface, in contrast to the previously observed ice-like structure of water at electrolyte/oxide interfaces. [less ▲]

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See detailPotentialisation de l'activité somatogénique de la somatotropine bovine (bGH) par des anticorps monoclonaux anti-bGH
Massart, Serge; Portetelle, Daniel ULg; Maiter, Dominique et al

Poster (1990)

Detailed reference viewed: 11 (2 ULg)