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Peer Reviewed
See detailMulti-biomaterial for controlled release of active substances
Zalfen, Alina; Nizet, Dominique; Jérôme, Christine ULg et al

Poster (2006)

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Peer Reviewed
See detailMulti-Camera People Tracking by Collaborative Particle Filters and Principal Axis-Based Integration
Du, Wei ULg; Piater, Justus ULg

in Asian Conference on Computer Vision (2007)

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See detailA multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants.
Sharma, Manu; Ioannidis, John P. A.; Aasly, Jan O. et al

in Journal of Medical Genetics (2012), 49(11), 721-6

BACKGROUND: Two recent studies identified a mutation (p.Asp620Asn) in the vacuolar protein sorting 35 gene as a cause for an autosomal dominant form of Parkinson disease . Although additional missense ... [more ▼]

BACKGROUND: Two recent studies identified a mutation (p.Asp620Asn) in the vacuolar protein sorting 35 gene as a cause for an autosomal dominant form of Parkinson disease . Although additional missense variants were described, their pathogenic role yet remains inconclusive. METHODS AND RESULTS: We performed the largest multi-center study to ascertain the frequency and pathogenicity of the reported vacuolar protein sorting 35 gene variants in more than 15,000 individuals worldwide. p.Asp620Asn was detected in 5 familial and 2 sporadic PD cases and not in healthy controls, p.Leu774Met in 6 cases and 1 control, p.Gly51Ser in 3 cases and 2 controls. Overall analyses did not reveal any significant increased risk for p.Leu774Met and p.Gly51Ser in our cohort. CONCLUSIONS: Our study apart from identifying the p.Asp620Asn variant in familial cases also identified it in idiopathic Parkinson disease cases, and thus provides genetic evidence for a role of p.Asp620Asn in Parkinson disease in different populations worldwide. [less ▲]

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See detailMulti-Chromatic Analysis of SAR Images for Coherent Target Detection
Bovenga, Fabio; Barbier, Christian ULg; De Rauw, Dominique ULg et al

in Remote Sensing (2014), 6

This work investigates the possibility of performing target analysis through the Multi-Chromatic Analysis (MCA), a technique that basically explores the information content of sub-band images obtained by ... [more ▼]

This work investigates the possibility of performing target analysis through the Multi-Chromatic Analysis (MCA), a technique that basically explores the information content of sub-band images obtained by processing portions of the range spectrum of a synthetic aperture radar (SAR) image. According to the behavior of the SAR signal at the different sub-bands, MCA allows target classification. Two strategies have been experimented by processing TerraSAR-X images acquired over the Venice Lagoon, Italy: one exploiting the phase of interferometric sub-band pairs, the other using the spectral coherence derived by computing the coherence between sub-band images of a single SAR acquisition. The first approach introduces the concept of frequency-persistent scatterers (FPS), which is complementary to that of the time-persistent scatterers (PS). FPS and PS populations have been derived and analyzed to evaluate the respective characteristics and the physical nature of the targets. Spectral coherence analysis has been applied to vessel detection, according to the property that, in presence of a random distribution of surface scatterers, as for open sea surfaces, spectral coherence is expected to be proportional to sub-band intersection, while in presence of manmade structures it is preserved anyhow. First results show that spectral coherence is well preserved even for very small vessels, and can be used as a complementary information channel to constrain vessel detection in addition to classical Constant False Alarm Rate techniques based on the sole intensity channel. [less ▲]

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See detailMulti-Cité, une expérience de formation initiale inédite
Beckers, Jacqueline ULg; Stegen, Pierre; Merenne-Schoumaker, Bernadette ULg et al

in Puzzle (1997), 2(juin), 10-16

L'article présente l'expérience de formation co-jointe de futurs professeurs de géographie de l'ULg et de la Haute Ecole Charlemagne via la réalisation d'un jeu pédagogique portant sur la gestion urbaine ... [more ▼]

L'article présente l'expérience de formation co-jointe de futurs professeurs de géographie de l'ULg et de la Haute Ecole Charlemagne via la réalisation d'un jeu pédagogique portant sur la gestion urbaine, jeu publié dans GEO 41. [less ▲]

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See detailMulti-city network on drug mesure trends
Honore, A.; Amraei, M.; Bils, L. et al

Report (1999)

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See detailMulti-Criteria Decision Support for Cost Assessment Techniques in Shipbuilding Industry
Caprace, Jean-David ULg; Rigo, Philippe ULg

in COMPIT'09, Budapest (2009, May 10)

Cost is perhaps the most influential factor in the outcome of a product or service within many of today’s industries. Cost assessment during the early stage of ship design is crucial. It influences the go ... [more ▼]

Cost is perhaps the most influential factor in the outcome of a product or service within many of today’s industries. Cost assessment during the early stage of ship design is crucial. It influences the go, no-go decision concerning a new development. Cost assessment occurs at various stages of ship design development. Economic evaluation as early as possible, in the design phase, is therefore crucial to find the best price–function compromise for the ship projects. This paper presents a Multi Criteria Decision Aid (MCDA) method in order to select an appropriate cost assessment method at each stage of the ship design. In order to compare the cost performance between all alternatives, the evaluation of each alternative is performed by PROMETHEE. [less ▲]

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See detailMulti-criteria Scantling Optimisation of Cruise Ships
Caprace, Jean-David ULg; Bair, Frédéric ULg; Rigo, Philippe ULg

in Ship Technology Research = Schiffstechnik (2010), 20

A numerical tool for the optimisation of the scantlings of a ship is extended by considering production cost, weight and moment of iner tia in the objective function. A multi-criteria optimisation of a ... [more ▼]

A numerical tool for the optimisation of the scantlings of a ship is extended by considering production cost, weight and moment of iner tia in the objective function. A multi-criteria optimisation of a passenger ship is conducted to illustrate the analysis process. Pareto frontiers are obtained and results are verified with Bureau Veritas rules. [less ▲]

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See detailMulti-Criteria Selection of Hydraulic Gates
Daniel, R.; Dembick, E.; Rigo, Philippe ULg

in International Navigation Seminar, PIANC AGA2008, Beijing, China Communication Press (CIP), Beijing, China, May 2008 (2008, May)

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See detailMulti-criterion Scantling Optimisation of Passenger Ships
Caprace, Jean-David ULg; Bair, Frédéric ULg; Rigo, Philippe ULg

in 9th International Conference on Computer Applications and Information Technology in the Maritime Industries (2010, April 12)

In the scantling design of a passenger ship, minimum production cost, minimum weight and maximum moment of inertia (stiffness) are conflicting objectives. For that purpose, recent improvements were made ... [more ▼]

In the scantling design of a passenger ship, minimum production cost, minimum weight and maximum moment of inertia (stiffness) are conflicting objectives. For that purpose, recent improvements were made to the LBR-5 software (French acronym of “Stiffened Panels Software”, version 5.0) to optimize the scantling of ship sections by considering production cost, weight and moment of inertia in the optimisation objective function. A real multi-criterion optimisation of a passenger ship is presented in this paper. Results highlight that LBR-5 is competitive software to optimise scantling of ships at very early design stage with management of critical problems studied normally at a later step of the design. [less ▲]

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See detailMulti-decadal carbon and water relations of African tropical humid forests: a tree-ring stable isotope analysis
Hufkens, Koen; Helle, Gerd; de Haulleville, Thalès ULg et al

Conference (2013, April 10)

Little is known about the temporal dynamics of the carbon sequestering capacity and dynamics of African tropical humid forest ecosystems in response to various environmental drivers. This lack of ... [more ▼]

Little is known about the temporal dynamics of the carbon sequestering capacity and dynamics of African tropical humid forest ecosystems in response to various environmental drivers. This lack of knowledge is mainly due to the absence of ecosystem scale flux measurements of gas exchange. However, tree growth often displays itself as alternating pattern of visible rings due to the seasonally varying growth speed of the vascular cambium. Consequently, analysis of tree growth through tree-ring analysis provides us with insights into past responses of the carbon sequestering capacity of key species to abrupt ecosystem disturbances and, while slower, a changing climate. Not only does the width and density of growth rings reflect annual growth but their isotopic composition of 13C/12C and 18O/16O isotopes also reveal the environmental conditions in which the trees were growing. In particular, stable isotope ratios in tree-rings of carbon are influenced by fractionation through carboxylation during photosynthesis and changes in leaf stomatal conductance. Similarly, fractionation of oxygen isotopes of soil water occurs at the leaf level through evapo-transipiration. As a consequence, 18O/16O (δ 18O) values in wood cores will reflect both the signal of the source water as well as that of for example summer humidity. Therefore, both C and O stable isotopes might not only be valuable as proxy data for past climatic conditions but they also serve as an important tool in understanding carbon and water relations within a tropical forest ecosystems. To this end we correlate long term climate records (1961 – present) with tree ring measurement of incremental growth and high resolution analysis of tree-core stable isotope composition(δ 13C , δ 18O) at a tropical humid forests in the DR Congo. The Yangambi Man And Biosphere (MAB) reserve is located in the north-eastern part of DR Congo, with a distinct tropical rainforest climate. In addition to the tree-core data records and extensive meteorological records collected at both sites, observations on green leaf phenology of key species will provide us with additional information on potential carbon sequestration dynamics. Because, phenology is a first order control on plant productivity. In this unique study, using detailed tree-ring analyses together with auxiliary data, we explore the temporal dynamics of carbon and water relations and the influence on carbon sequestration of key tree species in African tropical humid forests. [less ▲]

Detailed reference viewed: 11 (0 ULg)
Peer Reviewed
See detailMulti-dectector row computed tomography of the carpal joint in dogs
Cavrenne; Bolen, Géraldine ULg; DeBusscher et al

Poster (2007)

Detailed reference viewed: 7 (1 ULg)
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See detailMulti-dimensional sets recognizable in all abstract numeration systems
Charlier, Emilie ULg; Lacroix, Anne ULg; Rampersad, Narad ULg

in RAIRO : Informatique Théorique et Applications = Theoretical Informatics and Applications (2012), 46(1), 51-65

We prove that the subsets of N^d that are S-recognizable for all abstract numeration systems S are exactly the 1-recognizable sets. This generalizes a result of Lecomte and Rigo in the one-dimensional ... [more ▼]

We prove that the subsets of N^d that are S-recognizable for all abstract numeration systems S are exactly the 1-recognizable sets. This generalizes a result of Lecomte and Rigo in the one-dimensional setting. [less ▲]

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See detailMulti-Dimensional Vector Assignment Problems
Dokka, Trivikram; Crama, Yves ULg; Spieksma, Frits C.R.

in Discrete Optimization (2014), 14

We consider a special class of axial multi-dimensional assignment problems called multi- dimensional vector assignment (MVA) problems. An instance of the MVA problem is defined by m disjoint sets, each of ... [more ▼]

We consider a special class of axial multi-dimensional assignment problems called multi- dimensional vector assignment (MVA) problems. An instance of the MVA problem is defined by m disjoint sets, each of which contains the same number n of p-dimensional vectors with nonnegative integral components, and a cost function defined on vectors. The cost of an m-tuple of vectors is defined as the cost of their component-wise maximum. The problem is now to partition the m sets of vectors into n m-tuples so that no two vectors from the same set are in the same m-tuple and so that the sum of the costs of the m-tuples is minimized. The main motivation comes from a yield optimization problem in semi-conductor manufacturing. We consider a particular class of polynomial-time heuristics for MVA, namely the sequential heuristics, and we study their approximation ratio. In particular, we show that when the cost function is monotone and subadditive, sequential heuristics have a finite approximation ratio for every fixed m. Moreover, we establish smaller approximation ratios when the cost function is submodular and, for a specific sequential heuristic, when the cost function is additive. We provide examples to illustrate the tightness of our analysis. Furthermore, we show that the MVA problem is APX-hard even for the case m = 3 and for binary input vectors. Finally, we show that the problem can be solved in polynomial time in the special case of binary vectors with fixed dimension p. [less ▲]

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See detailMulti-disciplinary approach for sediment dynamics study of active floodplains
Gautier, E.; Corbonnois, J.; Petit, François ULg et al

in Géomorphologie : Relief, Processus, Environnement (2009)

Detailed reference viewed: 71 (22 ULg)
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See detailMulti-disciplinary investigation of the tomb of Menna (TT69), Theban Necropolis, Egypt
Vandenabeele, Peter; Garcia-Moreno, Renata; Mathis, François ULg et al

in Spectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy (2009), 73(3), 546-552

The archaeometrical survey of the tomb of Menna (TT69), which took place in November-December 2007, is part of the extended research program that aims to study and preserve this tomb in all its aspects ... [more ▼]

The archaeometrical survey of the tomb of Menna (TT69), which took place in November-December 2007, is part of the extended research program that aims to study and preserve this tomb in all its aspects. Menna was a high official who served as an overseer of Cadastral surveys during the reigns of pharaohs Tuthmosis IV and Amenhotep Ill (ca. 1419-1370 BC). The research team aimed to gather information, in a totally non-destructive way, on the materials used and the painting techniques. The technical examinations included photography with normal and raking light. macrophotography, ultra-violet (UV) fluorescence photography, and microscopy. On selected points X-ray fluorescence (XRF) was combined with diffuse reflectance UV-spectrometry, near infrared (NIR) diffuse reflectance spectroscopy and Raman spectroscopy. The technical aspects as well as problems that are inherently associated with an interdisciplinary survey of this extent, are discussed. The project worked with a large team of people with different backgrounds and sensitive technical equipment. Working conditions were quite hostile, including elevated temperatures and dust hampering the examinations. (C) 2008 Elsevier B.V. All rights reserved. [less ▲]

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See detailMulti-disciplinary research on long-term Middle to Upper Devonian fore-reef successions from Germany and Austria
Pas, Damien ULg; Da Silva, Anne-Christine ULg; Cornet, Pierre et al

in Kido, Erika; Suttner, Thomas; Werer, Piller (Eds.) et al Berichte des Institutes für Erdwissenschaften, Karl-Franzens-Universität Graz (2012, June)

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See detailMulti-Domain Approaches for the Solution of High-Frequency Time-Harmonic Propagation Problems
Vion, Alexandre ULg

Doctoral thesis (2014)

The numerical solution of high-frequency time-harmonic propagation problems by volumic discretization methods is a challenging task, most notably because of the very large size of the resulting linear ... [more ▼]

The numerical solution of high-frequency time-harmonic propagation problems by volumic discretization methods is a challenging task, most notably because of the very large size of the resulting linear systems. We present a framework for a class of iterative methods that distribute the work between several CPUs and exchange information between physical or artificial interfaces. The goal is to define subproblems of manageable sizes, and to exploit the power of parallel supercomputers. [less ▲]

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See detailMulti-drug resistance in a canine lymphoid cell line due to increased P-glycoprotein expression, a potential model for drug-resistant canine lymphoma.
Zandvliet, M.; Teske, Erik ULg; Schrickx, J. A.

in Toxicology in vitro : an international journal published in association with BIBRA (2014), 28(8), 1498-506

Canine lymphoma is routinely treated with a doxorubicin-based multidrug chemotherapy protocol, and although treatment is initially successful, tumor recurrence is common and associated with therapy ... [more ▼]

Canine lymphoma is routinely treated with a doxorubicin-based multidrug chemotherapy protocol, and although treatment is initially successful, tumor recurrence is common and associated with therapy resistance. Active efflux of chemotherapeutic agents by transporter proteins of the ATP-Binding Cassette superfamily forms an effective cellular defense mechanism and a high expression of these transporters is frequently observed in chemotherapy-resistant tumors in both humans and dogs. In this study we describe the ABC-transporter expression in a canine lymphoid cell line and a sub-cell line with acquired drug resistance following prolonged exposure to doxorubicin. This sub-cell line was more resistant to doxorubicin and vincristine, but not to prednisolone, and had a highly increased P-glycoprotein (P-gp/abcb1) expression and transport capacity for the P-gp model-substrate rhodamine123. Both resistance to doxorubicin and vincristine, and rhodamine123 transport capacity were fully reversed by the P-gp inhibitor PSC833. No changes were observed in the expression and function of the ABC-transporters MRP-1 and BCRP. It is concluded that GL-40 cells represent a useful model for studying P-gp dependent drug resistance in canine lymphoid neoplasia, and that this model can be used for screening substances as potential P-gp substrates and their capacity to modulate P-gp mediated drug resistance. [less ▲]

Detailed reference viewed: 84 (1 ULg)