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See detailReelin signaling directly affects radial glia morphology and biochemical maturation
Hartfuss, Eva; Forster, Eckart; Bock, Hans H. et al

in Development (2003), 130(19), 4597-4609

Radial glial cells are characterized, besides their astroglial properties, by long radial processes extending from the ventricular zone to the pial surface, a crucial feature for the radial migration of ... [more ▼]

Radial glial cells are characterized, besides their astroglial properties, by long radial processes extending from the ventricular zone to the pial surface, a crucial feature for the radial migration of neurons. The molecular signals that regulate this characteristic morphology, however, are largely unknown. We show an important role of the secreted molecule reelin for the establishment of radial glia processes. We describe a significant reduction in ventricular zone cells with long radial processes in the absence of reelin in the cortex of reeler mutant mice. These defects were correlated to a decrease in the content of brain lipid-binding protein (Blbp) and were detected exclusively in the cerebral cortex, but not in the basal ganglia of reeler mice. Conversely, reelin addition in vitro increased the Blbp content and process extension of radial glia from the cortex, but not the basal ganglia. Isolation of radial glia by fluorescent-activated cell sorting showed that these effects are due to direct signaling of reelin to radial glial cells. We could further demonstrate that this signaling requires Dab1, as the increase in Blbp upon reelin addition failed to occur in Dab1(-/-) mice. Taken together, these results unravel a novel role of reelin signaling to radial glial cells that is crucial for the regulation of their Blbp content and characteristic morphology in a region-specific manner. [less ▲]

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See detailRéémergence de la trypanosomiase humaine africaine dans la province ville de Kinshasa, République démocratique du Congo (RDC)
Tshimumgu, K.; Okenge, L. N.; De Mol, Patrick ULg

in Médecine et Maladies Infectieuses (2010), 40(8), 462-467

BACKGROUND: The incidence of human African trypanosomiasis (HAT) or sleeping sickness in Kinshasa has been increasing since 1996. The objectives of this study were first to identify the optimal levels of ... [more ▼]

BACKGROUND: The incidence of human African trypanosomiasis (HAT) or sleeping sickness in Kinshasa has been increasing since 1996. The objectives of this study were first to identify the optimal levels of knowledge, and then to determine the risk factors for HAT in the city of Kinshasa. METHODS: This case/control study was based on a structured questionnaire. Case-patients were detected and treated between 1 January 2004 and 31 December 2005. Each case-patient was paired with two seronegative controls of the same age and sex, living in the same type of environment. The study included 437 case-patients and 874 controls. RESULTS: The optimal level of knowledge defined by the list of elementary notions related to HAT was 44% for the case-patients and 37.0% for controls (p<0.0001). The majority of individuals (86.7%) was favorable to passive screening. The patients living in peripheral areas were more at risk than other groups, in rural areas (odds-ratio 12.1; 95% IC: 5.7-21.7), and remote areas (odds-ratio 8.9; 9% IC: 2.1-38.8). A family history of HAT (odds-ratio 12.9; 95% IC: 7.9-20.8), ignoring the transmission route (odds-ratio 11.2; 95% IC: 5.8-21.7), and the water supply in natural points (odds-ratio 6.9; 95% IC: 2.8-17.2) were also risk factors. CONCLUSION: The results identified avoidable factors, which could be taken into account, to decrease the incidence of new contamination, the morbidity, and mortality of HAT. [less ▲]

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See detailLe reengineering : aspects sociaux
Cornet, Annie ULg

Doctoral thesis (1998)

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See detailRéentraînement/reconditionnement et troubles cognitifs: les réserves cognitives
Adam, Stéphane ULg

Conference (2009, December 04)

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See detailReevaluation by Image Analysis of the Effects of Fibroblasts, Fibronectin or Laminin Upon Colony Formation in Mouse Lungs by B16 Melanoma Cells
Coucke, P. H.; Lambertz, M.; Baramova, E. N. et al

in Invasion & Metastasis (1993), 13(4), 201-11

A recently described personal method based on image analysis of histological sections was used in order to quantify lung colony formation by B16 melanoma cells injected intravenously into the mouse. These ... [more ▼]

A recently described personal method based on image analysis of histological sections was used in order to quantify lung colony formation by B16 melanoma cells injected intravenously into the mouse. These tumor cells were preincubated in vitro either with fibronectin (FN), laminin (LN) or fibroblasts (FB), which are implicated in the process of invasion and metastasis. Thanks to this method, a more accurate analysis of lung colonies (section area and number) formed by tumor cells was realized. By image analysis, we show that when FB were mixed with B16 cells, a drastic increase of tumor sections number and area was induced. LN increased the tumor sections area, but not their number. No effect of FN on B16 cells was observed. LN and FN promoted tumor anchorage in the depth of the lungs while FB reduced the latter. These facts could explain the contradictory results obtained by simply counting macroscopically superficial lung colonies. When cultured in vitro, these B16 melanoma cells did not produce any type of IV collagenase, either alone or in the presence of LN or FN, but in cocultures (B16 with 3T3) and in fibroblasts cultures, this enzyme was present. This could explain, among other factors, why the rate of invasiveness exerted by B16 cells is higher when the latter are coinjected with FB. [less ▲]

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See detailLa réévaluation des créances d'enrichissement sans cause entre ex-époux séparés de biens
Leleu, Yves-Henri ULg

in Journal des Tribunaux (2012), 6497

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See detailLa réévaluation des récompenses encore en questions?
Leleu, Yves-Henri ULg; Laruelle, Julie ULg

in Revue du Notariat Belge (2011)

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See detailReevaluation of the role of VEGF-B suggests a restricted role in the revascularization of the ischemic myocardium .
Li, X.; Tjwa, M.; Van Hove, I. et al

in Arteriosclerosis and Thrombosis : A Journal of Vascular Biology (2008), 28(9), 1614-20

OBJECTIVE: The endogenous role of the VEGF family member vascular endothelial growth factor-B (VEGF-B) in pathological angiogenesis remains unclear. METHODS AND RESULTS: We studied the role of VEGF-B in ... [more ▼]

OBJECTIVE: The endogenous role of the VEGF family member vascular endothelial growth factor-B (VEGF-B) in pathological angiogenesis remains unclear. METHODS AND RESULTS: We studied the role of VEGF-B in various models of pathological angiogenesis using mice lacking VEGF-B (VEGF-B(-/-)) or overexpressing VEGF-B(167). After occlusion of the left coronary artery, VEGF-B deficiency impaired vessel growth in the ischemic myocardium whereas, in wild-type mice, VEGF-B(167) overexpression enhanced revascularization of the infarct and ischemic border zone. By contrast, VEGF-B deficiency did not affect vessel growth in the wounded skin, hypoxic lung, ischemic retina, or ischemic limb. Moreover, VEGF-B(167) overexpression failed to enhance vascular growth in the skin or ischemic limb. CONCLUSIONS: VEGF-B appears to have a relatively restricted angiogenic activity in the ischemic heart. These insights might offer novel therapeutic opportunities [less ▲]

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See detailLe réexamen des collections de Spy
Semal, P.; Rougier, H.; Crevecoeur, I. et al

in Di Modica, K.; Jungels, C. (Eds.) Paléolithique moyen en Wallonie. La collection Louis Eloy (2009)

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See detailRéexamen du dessin du codex miscellaneus de Montserrat (P. Montserrat inv. nr. 154 = MP³ 2916.41)
Macedo, Gabriel ULg

in Aegyptus (in press), 90

New interpretation of the drawing of a mythological hero in the 4th Montserrat codex miscellaneus.

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See detailReexamination of the Branly effect
Dorbolo, Stéphane ULg; Ausloos, Marcel ULg; Vandewalle, Nicolas ULg

in Physical Review E (2003), 67(4, Pt 1), 40302

The electrical resistance of a metallic granular packing has been recorded at room temperature. A nearby burster between which sparks are produced, induces a decrease in the resistance of the granular ... [more ▼]

The electrical resistance of a metallic granular packing has been recorded at room temperature. A nearby burster between which sparks are produced, induces a decrease in the resistance of the granular packing as described in the works of Branly. Our measurements emphasize that the decrease is continuous and the resistance variations behave like a stretched exponential law due to the creation of new electrical paths as in nucleation-growth soldering processes. This behavior has been identified to be a diffusionlike process. [less ▲]

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See detailRefaire société. Les enjeux des politiques européennes de cohésion sociale
Vrancken, Didier ULg

Scientific conference (2011, October 28)

A partir de l’examen des différents Plans de Cohésion Sociale (PCS) qui ont vu le jour sous l’impulsion des politiques européennes et ce, dans un contexte de crise de modèle des Etats sociaux européens ... [more ▼]

A partir de l’examen des différents Plans de Cohésion Sociale (PCS) qui ont vu le jour sous l’impulsion des politiques européennes et ce, dans un contexte de crise de modèle des Etats sociaux européens, cet exposé proposera une approche critique des tentatives actuelles de recomposition des politiques sociales. Ce mouvement puise largement son inspiration dans un projet de participation de tous au sein de la société. Il s’agit désormais d’animer, de faire participer, d’inciter, de produire de l’intégration là où autrefois l’action publique visait prioritairement à protéger, à conférer un statut et une position sociale. Une nouvelle intention publique aurait fait son apparition dans le champ des politiques sociales. Elle viserait davantage à solliciter les individus, à faire appel à leur subjectivité tout en multipliant les lieux d’écoute. Toutefois, pour devenir globalement plus individualisées et subjectives, les politiques sociales ont dû puiser là où précisément des politiques de la subjectivité étaient éprouvées de longue date, à savoir dans les schémas assistanciels de l’aide sociale. On assisterait ainsi à une reconfiguration des frontières du social. Saisi de nouvelles attentes plus singulières et particularistes, il puiserait de plus en plus largement son inspiration aux sources du travail social, se « travaillerait », se mettrait en action par l’intermédiaire d’intervenants rompus aux techniques relationnelles et aux conduites d’entretien [less ▲]

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See detailLe référé judiciaire
Boularbah, Hakim ULg; Englebert, Jacques

Book published by Editions du jeune barreau (2003)

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See detailReferee education in Wallonia - The case of the team sports with interpenetration
Van Hoye, Martin ULg; Mottard, Baptiste; Cloes, Marc ULg

Poster (2013, July)

The referees are responsible for the proper progress of sports competitions. However, it is clear that very few studies are devoted to them, particularly with regard to their training. The aim of this ... [more ▼]

The referees are responsible for the proper progress of sports competitions. However, it is clear that very few studies are devoted to them, particularly with regard to their training. The aim of this study was to analyze the Wallonian situation in five federations: basketball, football, handball, hockey and rugby. We conducted semi-structured interviews with three officials of their refereeing commission. After the analysis of the data, subjects gave a feedback on the synthesis of the interviews (Friedberg, 1994). The SONAL software (v.1.6.11; Alber, 2010) allowed us to process the data. According to our subjects, no federation is genuinely interested by referees, as they prefer to focus more on other aspects ("sport for all", "promotion of their sport", "notoriety of the national team" …). The referee courses are purely theoretical and concluded with an examination (15/15). Then, supervisors follow the referees on the field but the lack of human resources is a real problem (15/15). Only the basketball federation offers learning levels, allowing a gradual advancement. The career-long learning is based on supervisions but also on seminars. The field's experience is the most important factor (15/15) to improve (Pizerra and Laborde, 2011). We noticed also that the football federation implemented refereeing training centers while the basketball federation has established a school of refereeing. In addition, the rugby referee educators must have a certificate of the international refereeing commission while any special skills are requested in the other federations. Except in hockey, all courses are free. In the five federations, the structures are extremely different. An identical framework with different invariable levels, as in coach education (Theunissen, 2007), could facilitate the implementation of interdisciplinary training. [less ▲]

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See detailLa référence à Augustin chez Husserl
Seron, Denis ULg

in Philosophique (2005)

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See detailLa référence au développement durable
Partoune, Christine ULg

in Tableau de bord "Participation et espaces publics" - Pour un développement et une gestion concertée des espaces publics (2010)

Aujourd’hui, la référence au "développement durable" est utilisée sans vergogne dans la publicité, a toutes les apparences d’une nouvelle vertu et est affichée comme telle dans tous les domaines. Pourtant ... [more ▼]

Aujourd’hui, la référence au "développement durable" est utilisée sans vergogne dans la publicité, a toutes les apparences d’une nouvelle vertu et est affichée comme telle dans tous les domaines. Pourtant, l’appellation peut s’avérer inconfortable car elle est contestée à plus d’un titre. Le but de cet article est d’attirer l’attention des animateurs territoriaux sur l’importance de garder une distance critique vis-à-vis de tout slogan aux allures dogmatiques, comme l’est devenu le développement durable. Il présente les limites du modèle classique généralement admis et questionne son utilité comme référence dans le développement et la gestion concertée des espaces publics. [less ▲]

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See detailReference mirroring for control with impacts
Forni, Fulvio ULg; Teel, Andrew; Zaccarian, Luca

in Daafouz, Jamal; Tarbouriech, Sophie; Sigalotti, Mario (Eds.) Hybrid Systems with Constraints (2013)

We illustrate a peculiar concept of mirrored reference to address reference tracking control systems for plants subject to impacts. The idea is based on the constructions of artificial references ... [more ▼]

We illustrate a peculiar concept of mirrored reference to address reference tracking control systems for plants subject to impacts. The idea is based on the constructions of artificial references corresponding to suitable reflections of the actual reference performed with respect to the impacting surfaces. We illustrate the application of this idea to reference tracking and state observation for a number of examples of control systems subject to impacts: a one-dimensional hammer hitting a surface, a two-dimensional Newton’s cradle, a two-dimensional mass moving in a planar equilateral triangle and a mass moving in an n-dimensional polyhedral region. For each one of these examples, we provide controllers inducing global exponential stability of the error dynamics. Despite the apparently different nature among the examples, we show that the controller/observer design follows the same paradigm based on mirrored references and we highlight the similarities of the different proofs by showing that they are all based on a specific result about Lyapunov conditions for global exponential stability of hybrid dynamical systems. [less ▲]

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See detailReference populations for shoulder studies should be selected carefully
Schwartz, Cédric ULg; Denoël, Vincent ULg; Bruls, Olivier ULg et al

Conference (2013, August 06)

To assess various shoulder pathologies / treatments, non pathological populations are often used as references. However, some factors may influence significantly the scapular kinematics within a healthy ... [more ▼]

To assess various shoulder pathologies / treatments, non pathological populations are often used as references. However, some factors may influence significantly the scapular kinematics within a healthy population and consequently alter the final kinematic evaluation. Results of 3D shoulder assessment found in this study show that small (≈5°) but significant differences exist between gender and between the dominant and non-dominant arms. Therefore the populations used for referential data should be selected carefully. [less ▲]

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See detailA reference section for neritic facies at the transition Late to Latest Famennian.
Streel, Maurice ULg; Maziane-Serraj, N; Marshall, JEA et al

in Subcommission on Devonian Stratigraphy Newsletter (2007), 22

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