Swelling behavior and release properties of pH-sensitive hydrogels based on methacrylic derivatives; ; Calberg, Cédric et alin Acta Pharmaceutica (Zagreb, Croatia) (2007), 57(3), 301-314 The purpose of this study is to develop novel intestinal-specific drug delivery systems with pH sensitive swelling and drug release properties. Methacrylic-type polymeric prodrugs were synthesized by free ... [more ▼] The purpose of this study is to develop novel intestinal-specific drug delivery systems with pH sensitive swelling and drug release properties. Methacrylic-type polymeric prodrugs were synthesized by free radical copolymerization of methacrylic acid, poly(ethyleneglycol monomethyl ether methacrylate) and a methacrylic derivative of N-(4-hydroxyphenyl)-2-(4-methoxyphenyl) acetamide in the presence of ethylene glycol dimethacrylate as crosslinking agent. The effect of copolymer composition on the swelling behavior and hydrolytic degradation were studied in simulated gastric (SGF, pH 1.2) and intestinal fluids (SIF, pH 7.0). The dynamic swelling behavior of these hydrogels was investigated to determine the mechanism of water transport through these hydrogels. The mechanism of water transport through the gels was significantly affected by the pH of the swelling medium and became more relaxation-controlled in a swelling medium of pH 7.0. The swelling and hydrolytic behaviors of hydrogels were dependent on the content of methacrylic acid (MAA) groups and caused a decrease and increase in gel swelling in SGF and SIF, respectively. Drug release studies showed that the increasing content of MAA acid in the copolymer enhances hydrolysis in SIF. These results suggest that pH-sensitive systems could be useful for preparation of a muccoadhesive system and controlled release of N-(4-hydroxyphenyl)-2-(4-methoxyphenyl) acetamide. [less ▲] Detailed reference viewed: 89 (4 ULg) The swelling behaviour of wheat starch granules during isothermal and non-isothermal treatmentsMalumba Kamba, Paul ; Jacquet, Nicolas ; Delimme, Guy et alin Journal of Food Engineering (2013), 114(2), 199-206 The size of wheat starch granules was measured during isothermal and non-isothermal treatments and fitted using mathematical models in order to elucidate the time–temperatures dependence of the swelling ... [more ▼] The size of wheat starch granules was measured during isothermal and non-isothermal treatments and fitted using mathematical models in order to elucidate the time–temperatures dependence of the swelling phenomenon and to improve our understanding of the mechanism followed by granules during gelatinization. Upon the onset temperature of gelatinization, starch granules size increase rapidly and tend to reach equilibrium values that depend on the temperature and heating rate applied. The most accurate fitting of granule size observed overall isothermal treatments was obtained with the third-order kinetic and the Weibull empirical models. The activation energy of swelling calculated for isothermal treatment varied between 41 and 318 kJ mol 1, depending on the mathematical model considered. Therefore, without a consensus on the mechanism and order of reaction followed during gelatinization, the meaningful of kinetic parameters calculated using mathematical models seems highly questionable. During non-isothermal treatments at lower heating rate, it seems like a limitation of the swelling capacity of granules was induced. This phenomenon was attributed to restructuration occurred inside of granules. So, forecasting the swelling behaviour of starch granules during non-isothermal treatment has to consider both the time–temperature and the heating rate applied. [less ▲] Detailed reference viewed: 24 (5 ULg) Swelling soil unpredictable by classical geotechnical tests; Marcoen, Jean Marie ![]() in Proceedings of the XIII meeting of International Society for Soil Mech. and Foundation Engineering (1994) Detailed reference viewed: 5 (3 ULg) 'Swept along on the wild Styx'. Mozart's Daemonic Presence in Nineteenth-Century Dutch PoetrySteyaert, Kris ![]() in Görner, Rüdiger (Ed.) Mozart: eine Herausforderung für Literatur und Denken / Mozart: A Challenge for Literature and Thought (2007) Detailed reference viewed: 14 (4 ULg) Swimming ontogeny in Dicentrarchus labraxOlivier, Damien ; Parmentier, Eric ![]() Poster (2009, October) Detailed reference viewed: 8 (0 ULg) SWIMMING PUPPY SYNDROME IN A LITTER OF BOUVIER-DES-FLANDRES; ; Jauniaux, Thierry et alin Annales de Médecine Vétérinaire (1994), 138(2), 121-123 This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against ... [more ▼] This paper describes the clinical, serologic, electrophysiologic and pathologic findings in three Bouvier des Flandres puppies exhibiting the swiming puppy syndrome. The puppies had no antibodies against distemper virus, T. gondii and N. caninum. A myopathy was suspected because spontaneous activities were disclosed in all muscle groups and muscles enzymes were elevated. However the pathologic findings were unable to confirm this hypothesis. [less ▲] Detailed reference viewed: 45 (4 ULg) Switchable magnetic dipole induced guided vortex motion; Silhanek, Alejandro ; et alin Applied Physics Letters (2008), 93(2), We present evidence of magnetically controlled vortex motion in an Al film on top of a periodic array of Permalloy square rings. The resulting magnetic template generates a strongly anisotropic pinning ... [more ▼] We present evidence of magnetically controlled vortex motion in an Al film on top of a periodic array of Permalloy square rings. The resulting magnetic template generates a strongly anisotropic pinning potential landscape for vortices in the superconducting layer. Transport measurements show that this anisotropy is able to confine the flux motion along the high symmetry axes of the square lattice of dipoles. This guided vortex motion can be rerouted by 90 degrees simply changing the dipole orientation or even suppressed by inducing a flux-closure magnetic state with very low stray fields in the rings. (C) 2008 American Institute of Physics. [less ▲] Detailed reference viewed: 5 (1 ULg) Switchable magnetic dipole induced guided vortex motion (vol 93, 022507, 2008); Silhanek, Alejandro ; et alin Applied Physics Letters (2009), 94(21), erratum to the Appl. Phys. Lett. 93, 022507 (2008) Detailed reference viewed: 11 (1 ULg) Switching entanglement classes via local operationsBastin, Thierry ; ; et alPoster (2008) Detailed reference viewed: 5 (0 ULg) Switching mode of deformation in post-localization solutions with a quasi brittle material; ; Collin, Frédéric ![]() in Journal of Mechanics of Material and Structures (2006), 1(7), 1115-1134 Localization in a quasi brittle material is studied using a local second gradient model. Since localization takes place in a medium assumed to be initially homogeneous, non uniqueness of the solutions of ... [more ▼] Localization in a quasi brittle material is studied using a local second gradient model. Since localization takes place in a medium assumed to be initially homogeneous, non uniqueness of the solutions of an initial boundary value problem is then also studied. Using enhanced models implies to generalize the classical localization analysis, especially it is necessary to study solutions more continuous (i.e., continuous up to the degree one) than the ones used in analysis involving classical constitutive equations. Within the assumptions done, it appears that localization is possible in the second gradient model if it is possible in the underlying classical model. Then the study of non uniqueness is conducted for the numerical problem, using different first guesses in the full Newton-Raphson procedure solving the incremental non linear equations. It turns out ¯nally that we are able thanks to this method to reproduce qualitatively the non reproducibility of usual experiment in the post peak regime. [less ▲] Detailed reference viewed: 66 (11 ULg) SWOT en pédagogie universitaire : Questionner sa pratique d'enseignantPoumay, Marianne ![]() Learning material (2005) Detailed reference viewed: 164 (2 ULg) A SYBR Green RT-PCR assay in single tube to detect human and bovine noroviruses and control for inhibition.Scipioni, Alexandra ; Mauroy, Axel ; Ziant, Dominique et alin Virology journal (2008), 5 BACKGROUND: Noroviruses are single-stranded RNA viruses belonging to the family Caliciviridae. They are a major cause of epidemic and sporadic gastroenteritis in humans and clinical signs and lesions of ... [more ▼] BACKGROUND: Noroviruses are single-stranded RNA viruses belonging to the family Caliciviridae. They are a major cause of epidemic and sporadic gastroenteritis in humans and clinical signs and lesions of gastroenteritis were reported in bovines. Due to their genetic proximity, potential zoonotic transmission or animal reservoir can be hypothesized for noroviruses. RT-PCR has become the "gold standard" for the detection of noroviruses in faecal and environmental samples. With such samples, the control for inhibition of the reaction during amplification and detection is crucial to avoid false negative results, which might otherwise not be detected. The aim of the reported method is to detect, with a SYBR Green technology, a broad range of noroviruses with a control for inhibition. RESULTS: A SYBR Green real-time RT-PCR assay was developed making use of a foreign internal RNA control added in the same tube. This assay is able to detect human and bovine noroviruses belonging to genogroups I, II and III and to distinguish between norovirus and internal control amplicons using melting curve analysis. A 10-fold dilution of samples appears to be the method of choice to remove inhibition. This assay was validated with human and bovine stool samples previously tested for norovirus by conventional RT-PCR. CONCLUSION: This SYBR Green real-time RT-PCR assay allows the detection of the most important human and bovine noroviruses in the same assay, and avoids false negative results making use of an internal control. Melting curves allow the discrimination between the internal control and norovirus amplicons. It gives preliminary information about the species of origin. The sensitivity of the developed assay is higher than conventional RT-PCR and a 10-fold dilution of samples showed a better efficiency and reproducibility to remove RT-PCR inhibition than addition of bovine serum albumin. [less ▲] Detailed reference viewed: 60 (6 ULg) Syllabus "Deutsche Literaturgeschichte von 1945 bis zur GegenwartViehöver, Vera ![]() Learning material (2004) Detailed reference viewed: 13 (0 ULg) Syllabus "Kinder- und Jugendliteratur. Geschichte - Formen - Bewertungskriterien"Viehöver, Vera ![]() Learning material (2004) Detailed reference viewed: 11 (0 ULg) Syllabus à l'usage du cours de langue italienne IIMoreno, Paola ![]() Learning material (2009) Detailed reference viewed: 30 (0 ULg) Syllabus de droit romain; Gerkens, Jean-François ![]() Learning material (2005) Detailed reference viewed: 54 (2 ULg) Syllabus Histoire de la littérature néerlandaise ISteyaert, Kris ![]() Learning material (2011) Detailed reference viewed: 20 (4 ULg) Syllabus semi-interactif sur les exercices, procédés, techniques et stratégies didactiques utilisés dans l'enseignement des langues étrangèresSimons, Germain ![]() Learning material (1997) Ce syllabus propose aux étudiants de l'AESS/du Master en didactique des langues modernes un inventaire de différents exercices et procédés didactiques susceptibles d'être utilisés dans le cadre de la ... [more ▼] Ce syllabus propose aux étudiants de l'AESS/du Master en didactique des langues modernes un inventaire de différents exercices et procédés didactiques susceptibles d'être utilisés dans le cadre de la conception d'un plan de séquence didactique articulé autour du canevas didactique traditionnel : présentation > fixation > exploitation > évaluation. En outre, il reprend les exigences du service de didactique des langues modernes de l'ULg en matière de préparation des séquences didactiques. Enfin, il présente de nombreuses références bibliographiques relatives, entre autres, aux manuels de langues étrangères utilisés dans l'enseignement secondaire. [less ▲] Detailed reference viewed: 82 (4 ULg) Syllabus: Techniken des literaturwissenschaftlichen StudiumsViehöver, Vera ![]() Learning material (2011) Detailed reference viewed: 6 (2 ULg) La sylviculture d'arbres "objectif" ou d'arbres de place (cahier technique n°27); ; et al in Forêt Wallonne (2004), (68), 2-8 Ce cahier technique se présente en deux parties. La première est constituée du dossier remis à l’ensemble des agents de l’administration forestière lors des journées de formation. La seconde présente les ... [more ▼] Ce cahier technique se présente en deux parties. La première est constituée du dossier remis à l’ensemble des agents de l’administration forestière lors des journées de formation. La seconde présente les exercices de la formation ainsi que les résultats obtenus. Complémentaires, ces deux parties cherchent à confronter la théorie et la pratique, l’exposé académique et les discussions à bâtons rompus. Cette formation a été délivrée, dans le contexte de l’accord cadre de recherche forestière liant l’Université Catholique de Louvain, la Faculté universitaire des Sciences agronomiques de Gembloux et l’asbl Forêt Wallonne, à l’ensemble des agents forestiers des cantonnements de la Région wallonne. [less ▲] Detailed reference viewed: 59 (8 ULg) |
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