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See detailProfile of nimesulide and nimesulide-L-lysine-β-cyclodextrin on chondrocyte metabolism
De Leval, X.; Dogne, J.-M.; Masereel, B. et al

in Fundamental & Clinical Pharmacology (2000), 14

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See detailProfile of pediatric Crohn's disease in Belgium.
De Greef, E.; Mahachie John, Jestinah ULg; Hoffman, I. et al

in Journal of Crohn's & colitis (2013), 7(11), 588-98

AIM: A Belgian registry for pediatric Crohn's disease, BELCRO, was created. This first report aims at describing disease presentation and phenotype and determining associations between variables at ... [more ▼]

AIM: A Belgian registry for pediatric Crohn's disease, BELCRO, was created. This first report aims at describing disease presentation and phenotype and determining associations between variables at diagnosis and registration in the database. METHODS: Through a collaborative network, children with previously established Crohn's disease and newly diagnosed children and adolescents (under 18 y of age) were recruited over a 2 year period. Data were collected by 23 centers and entered in a database. Statistical association tests analyzed relationships between variables of interest at diagnosis. RESULTS: Two hundred fifty-five patients were included. Median age at diagnosis was 12.5 y (range: 1.6-18 y); median duration of symptoms prior to diagnosis was 3 m (range: 1-12 m). Neonatal history and previous medical history did not influence disease onset nor disease behavior. Fifty three % of these patients presented with a BMI z-score < -1. CRP was an independent predictor of disease severity. Steroids were widely used as initial treatment in moderate to severe and extensive disease. Over time, immunomodulators and biological were prescribed more frequently, reflecting a lower prescription rate for steroids and 5-ASA. A positive family history was the sole significant determinant for earlier use of immunosuppression. CONCLUSION: In Belgium, the median age of children presenting with Crohn's disease is 12.5 y. Faltering growth, extensive disease and upper GI involvement are frequent. CRP is an independent predictive factor of disease activity. A positive family history appears to be the main determinant for initial treatment choice. [less ▲]

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See detailProfile of soluble cytokine receptors in Crohn's disease
Gustot, T.; Lemmers, A.; Louis, Edouard ULg et al

in Gut (2005), 54(4), 488-495

Introduction: Soluble cytokine receptors (sCRs) modulate the in vivo activity of cytokines. Deficient sCR production could participate in the pathogenesis and course of Crohn's disease ( CD). The aim of ... [more ▼]

Introduction: Soluble cytokine receptors (sCRs) modulate the in vivo activity of cytokines. Deficient sCR production could participate in the pathogenesis and course of Crohn's disease ( CD). The aim of the study was to examine the profile of sCRs in CD patients and their modulation by infliximab and corticosteroids. Methods: We prospectively examined active CD patients (aCD) treated with either infliximab (n=21) or corticosteroids (n=9), CD patients in clinical remission (rCD, n=20), ulcerative colitis patients (UC, n=24), and healthy subjects (HS, n=15). Cultures of colonic biopsies were also examined from CD inflamed (n=8), CD non-inflamed (n=7), and healthy mucosa (n=8). Levels of tumour necrosis factor alpha (TNF-alpha), soluble TNF receptor I (sTNFRI), soluble TNF receptor II (sTNFRII), interleukin 1 beta (IL-1 beta), soluble IL-1 receptor I (sIL-1RI), soluble IL-1 receptor II (sIL-1RII), IL-6, soluble IL-6 receptor (sIL-6R), and sgp130 were measured using ELISA. Results: Higher levels of sTNFRI (p<0.05, p<0.01), sTNFRII (p<0.01, p<0.01), sIL-1RI (p<0.05, NS), IL-6 (p<0.01, p<0.01), and sIL-6R (p<0.05, NS) were observed in aCD compared with rCD and HS. Interestingly, sIL-1RII (p<0.05, p<0.01) and sgp130 (p<0.01, p<0.01) were profoundly decreased in aCD compared with rCD and HS, and were negatively correlated with CRP. Deficient production of sIL-1RII was specific to CD ( not observed in ulcerative colitis), and was further confirmed at the mucosal level. Infliximab decreased sTNFRII at one and four weeks (p<0.05) and enhanced sIL-6R levels at one week (p<0.05). Corticosteroids increased sIL-1RII levels at one week (p<0.05). Conclusion: CD is associated with dysregulated production of sCRs. Deficiency in sIL-1RII and sgp130 may be essential to CD pathogenesis. Their replacement through the use of fusion proteins could represent future alternative therapeutic strategies for CD. [less ▲]

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See detailThe profile of the absorption lines in rotating stars, taking into account the variation of ionization due to centrifugal force
Swings, Polydore ULg; Chandrasekhar, S.

in Monthly Notices of the Royal Astronomical Society (1936), 96(9), 883-889

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See detailProfiles of a Key Programme: Gravitational Lensing
Surdej, Jean ULg; Arnaud, J.; Borgeest, U. et al

in The Messenger (1989), 55

Prior to Professor van der Laan's enquiry, in the March 1988 issue of the Messenger, on the general interest among astronomers from the European community to possibly participate in Key Programmes (KPs ... [more ▼]

Prior to Professor van der Laan's enquiry, in the March 1988 issue of the Messenger, on the general interest among astronomers from the European community to possibly participate in Key Programmes (KPs) at the European 80uthern Observatory, at least three distinct groups (including more than half of the above authors) were already involved in the study of "gravitational lensing" effects (see box on pages 10-11). Observations were being performed with the help of various telescopes on La 8illa as weil as at other observatories (VLA, CFHT, Palomar, Kitt Peak, etc.). [less ▲]

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See detailProfiles of pregnancy-associated glycoprotein (PAG) concentrations during gestation in swamp buffalo
Van Hahn, N; Viet Linh, N; Melo de Sousa, Noelita ULg et al

in Proceedings of the 10th World Buffalo Congress and 7th Asian Buffalo Congress (2013)

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See detailProfiles of stratospheric chlorine nitrate (ClONO2) from atmospheric trace molecule spectroscopy/ATLAS 1 infrared solar occultation spectra
Rinsland, Curtis P.; Gunson, M. R.; Abrams, M. C. et al

in Journal of Geophysical Research (1994), 99(D9), 18895-18900

Stratospheric volume mixing ratio profiles of chlorine nitrate (ClONO2) have been retrieved from 0.01-cm−1 resolution infrared solar occultation spectra recorded at latitudes between 14°N and 54°S by the ... [more ▼]

Stratospheric volume mixing ratio profiles of chlorine nitrate (ClONO2) have been retrieved from 0.01-cm−1 resolution infrared solar occultation spectra recorded at latitudes between 14°N and 54°S by the atmospheric trace molecule spectroscopy Fourier transform spectrometer during the ATLAS 1 shuttle mission (March 24 to April 2, 1992). The results were obtained from nonlinear least squares fittings of the ClONO2 v 4 band Q branch at 780.21 cm−1 with improved spectroscopic parameters generated on the basis of recent laboratory work. The individual profiles, which have an accuracy of about ±20%, are compared with previous observations and model calculations. [less ▲]

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See detailProfiles of the volatile organic compounds emitted by the masses of Abies nordmanniana somatic embryos at maintenance and maturation stages
Druart, Philippe; Michels, Franck ULg; Misson, Jean-Pierre et al

Poster (2014, February 07)

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See detailProfiling food consumption : comparison between USA and EU
Duquesne, Brigitte ULg; Matendo, Sadrac; Lebailly, Philippe ULg

in Competitiveness in Agriculture and the Food Industry: US and EU Perspectives (2006)

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See detailProfiling lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological pregnancy
Heusschen, Roy ULg; Freitag, Nancy; Tirado-Gonzalez, Irene et al

in Biology of Reproduction (2013)

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See detailProfiling the smell of death by TD-GCxGC-TOFMS
Stefanuto, Pierre-Hugues ULg; Stadler, S; Forbes, S et al

Poster (2012, May)

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See detailProfiling workers’ activity-travel behavior based on mobile phone data
Liu, Feng; Janssens, Davy; Wets, Geert et al

in Proceedings of the Third International Conference on the Analysis of Mobile Phone Datasets (NetMob) (2013)

Activity-based micro-simulation models typically predict 24-hour activity-travel patterns for each individual in a study area. These patterns reflect the characteristics of the available transportation ... [more ▼]

Activity-based micro-simulation models typically predict 24-hour activity-travel patterns for each individual in a study area. These patterns reflect the characteristics of the available transportation infrastructure and land-use system as well as individuals’ lifestyles and needs. However, the lack of a reliable benchmark to evaluate the generated patterns has been a major concern. To address this issue, we explore the possibility of using mobile phone data to build such a validation measure. Our investigation consists of three steps. First, the daily trajectory of locations, where a user performed activities, is constructed from the mobile phone records. To account for the discrepancy between the movements revealed by the call data and the real traces that the user has made, the daily trajectories are then transformed into travel sequences. Finally, all the inferred travel sequences are classified into typical activity-travel patterns which, in combination with their relative frequencies, define a profile. The established profile represents the activity-travel behavior in the study area, and thus can be used as a benchmark for the validation of the activity-based models. By comparing the benchmark profiles derived from the call data with statistics that stem from activity-travel surveys, the validation potential is demonstrated. In addition, a sensitivity analysis is carried out to assess how the results are affected by the different parameter settings defined in the profiling process. [less ▲]

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See detailProfils AMDP de déprimés endogènes et de déprimés non endogènes
Mormont, Christian ULg; Von Frenckell, Rémy

in Acta Psychiatrica Belgica (1987), 87(2), 197-200

Discusses the description of 95 patients with endogenous depression (ED) and 86 patients with nonendogenous depression (NED) with the 9th edition of the International Classification of Diseases. It is ... [more ▼]

Discusses the description of 95 patients with endogenous depression (ED) and 86 patients with nonendogenous depression (NED) with the 9th edition of the International Classification of Diseases. It is maintained that the multifactorial, comprehensive description of these samples as allowed by the Association of Methodology and Documentation in Psychiatry (AMDP) system scales illustrates similarities and differences: A common pattern characterized by anxiety, depression, retardation, and hostility is apparent; however, Depression and Apathy-Retardation scores are higher in ED, whereas Dramatization and Hostility scores are higher in NED. [less ▲]

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See detailProfils apoptotiques altérés chez les patients irradiés montrant une hypersensibilité
Ozsahim, M; Mirabell, R; Emery, G-C et al

Conference (1998)

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See detailLes profils d'entreprises sociales d'insertion
Davister, Catherine; Defourny, Jacques ULg; Grégoire, Olivier et al

in Gardin, Laurent; Laville, Jean-Louis; Nyssens, Marthe (Eds.) Entreprise sociale et insertion. Une perspective internationale (2012)

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See detailProfils de discordance et comportement d’élèves dans un contexte d’éducation physique belge francophone
Martel, Denis; Cloes, Marc ULg; Colina-Valdor, Xavier et al

in Carnel, Béatrice; Moniotte, Julien (Eds.) Intervention, Recherche et Formation: Quels enjeux, quelles transformations? (2013, September)

Les profils de discordance sont déterminés à partir des écarts entre l’auto-évaluation des élèves (AÉ) et leur prédiction de l’évaluation de l’éducateur physique à leur égard (PrÉ) concernant leur niveau ... [more ▼]

Les profils de discordance sont déterminés à partir des écarts entre l’auto-évaluation des élèves (AÉ) et leur prédiction de l’évaluation de l’éducateur physique à leur égard (PrÉ) concernant leur niveau de performance, leur coopération et l’intensité de leurs efforts en classe d’éducation physique et sportive (ÉPS) (Martel et al., 2011). Une étude québécoise a permis d’établir que plus les élèves s’estiment sous-évalués par leur enseignant sur ces trois dimensions, moins ils tendent à rapporter l’adoption de comportements positifs durant les cours d’ÉPS. Pour la présente étude, réalisée dans un contexte belge francophone, les objectifs étaient : (1) de déterminer les profils de discordance d’élèves (PDi), et (2) d’analyser la relation entre ces PDi et les comportements que disent adopter les élèves en ÉPS. Un total de 1271 élèves (722 filles, 549 garçons) âgés entre 11 et 20 ans, provenant des niveaux secondaires inférieur (n=857) et supérieur (n=414) d’écoles (N=4) de l’agglomération de Liège, ont volontairement participé à l’étude. Un questionnaire validé, adapté d’une version québécoise, a été complété par les élèves vers la fin de l’année scolaire en l’absence de l'éducateur physique. Les résultats, inférieurs à ceux d’autres études, révèlent que 25% des élèves expriment un profil de concordance parfaite entre leur AÉ et leur PrÉ, c’est-à-dire s’estiment évalués à leur juste valeur à la fois pour leur niveau de performance, leur coopération et leurs efforts en ÉPS. Par ailleurs, 56% des élèves s’estiment sous-évalués (discordance négative) sur une seule dimension (27,7%), deux dimensions (19,4%) ou trois dimensions (9,5%) simultanément. Enfin, les résultats confirment ceux de Martel et al. (2011), à savoir que plus les élèves se sentent sous-évalués, particulièrement ceux qui se sentent sous-évalués sur au moins deux dimensions, moins ils rapportent de comportements positifs (p< .001) que ceux qui perçoivent être davantage en accord avec leur enseignant. [less ▲]

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