Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailModulation of the biological action of bovine growth hormone by passive immunization in hypophysectomized rat.
Jacqmin, S.; Vleurick, L.; Renaville, Robert ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2000), 4(1),

Detailed reference viewed: 10 (2 ULg)
Peer Reviewed
See detailModulation of the biological action of bovinegrowth hormone by passive immunization in hypophysectomised rat.
Jacqmin, Sophie; Vleurick, Lieve; Renaville, Robert ULg et al

in 1st Belgian Workshop on Animal Endocrinology (1999, October 13)

Detailed reference viewed: 4 (0 ULg)
Full Text
Peer Reviewed
See detailModulation of The Biosynthetic Activity of Human-Skin Fibroblasts by Tumor-Cells
Noël, Agnès ULg; Nusgens, Betty ULg; Foidart, Jean-Michel ULg et al

in Abstracts for the 17th Annual Meeting of The European Society for Dermatological Research (1987)

Detailed reference viewed: 4 (1 ULg)
Full Text
Peer Reviewed
See detailModulation of the Clozapine Structure Increases Its Selectivity for the Dopamine D4 Receptor
Liégeois, Jean-François ULg; Bruhwyler, J.; Damas, Jacques ULg et al

in European Journal of Pharmacology (1995), 273(3), 1-3

Clozapine has a more marked affinity for the recently cloned dopamine D4 receptor than for the dopamine D2 receptor. In the search for a selective ligand for the dopamine D4 receptor, useful as a ... [more ▼]

Clozapine has a more marked affinity for the recently cloned dopamine D4 receptor than for the dopamine D2 receptor. In the search for a selective ligand for the dopamine D4 receptor, useful as a pharmacological tool or as a potent atypical antipsychotic, a pyridobenzodiazepine derivative bioisoster of clozapine, JL 18, 8-methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido [2,3-b][1,4]benzodiazepine, was found to be the most dopamine D4-selective ligand belonging to the diarylazepine class. Indeed, JL 18 binds to the dopamine D4 receptor with affinity up to 25 times superior to that for the dopamine D2 receptor and presents reduced affinities for other receptors. [less ▲]

Detailed reference viewed: 28 (2 ULg)
Peer Reviewed
See detailModulation of the Expression of Interstitial and Type-Iv Collagenases in Coculture of Ht1080 Fibrosarcoma Cells and Fibroblasts
Munaut, Carine ULg; Noël, Agnès ULg; Weidle, U. H. et al

in Invasion & Metastasis (1995), 15(5-6), 169-78

Members of the metalloproteinase family (MMPs) are known to play a crucial role in the metastatic cascade. Here, we report some investigations about the synthesis of interstitial and type-IV collagenases ... [more ▼]

Members of the metalloproteinase family (MMPs) are known to play a crucial role in the metastatic cascade. Here, we report some investigations about the synthesis of interstitial and type-IV collagenases (gelatinases A and B) in a model of coculture of human fibroblasts and HT 1080 fibrosarcoma cells. The interstitial collagenase activity, mainly found in the conditioned medium of fibroblasts, and its mRNA level were increased in the in vitro coculture model. In contrast, gelatinase A was produced by both cell types. The HT 1080 cells additionally synthesised gelatinase B. In coculture, an enhancement of gelatinase A and the presence of its activated form were observed. Northern blot analysis demonstrated that this enzymatic enhancement occurred at a pretranslational level. The stimulation of the interstitial collagenase activity was partially mediated through soluble factor(s), whereas increased gelatinase A appeared to require direct cell-cell interactions. The extracellular matrix component, type-I collagen, stimulated the enzymatic activities released by the individual cells, but it did not modulate the synthesis of interstitial collagenase in coculture. Our results demonstrate that distinct MMPs are modulated by distinct mechanisms, all depending on specific interactions between tumour cells and host fibroblasts. [less ▲]

Detailed reference viewed: 10 (0 ULg)
Full Text
Peer Reviewed
See detailModulation of the HSV-TK/ganciclovir bystander effect by n-butyrate in glioblastoma: correlation with gap-junction intercellular communication.
Robe, Pierre ULg; Jolois, Olivier ULg; Nguyen Khac, Minh-Tuan ULg et al

in International Journal of Oncology (2004), 25(1), 187-92

The efficacy of HSV-TK/ganciclovir gene therapy largely relies on the bystander effect, i.e. the ability of transfected cells to kill the adjacent, untrasfected cells. This mechanism itself depends ... [more ▼]

The efficacy of HSV-TK/ganciclovir gene therapy largely relies on the bystander effect, i.e. the ability of transfected cells to kill the adjacent, untrasfected cells. This mechanism itself depends chiefly on the transfer via gap junctions of phosphorylated ganciclovir between cells, and is often deficient in glioblastomas. In this report, we demonstrate that n-butyrate markedly enhances the gap junction intercellular communication of GJIC-deficient glioma cells, and significantly increases the bystander effect in such cells. This effect of n-butyrate appears to be independent from its HDAC inhibitory effect, since trichostatin A does not reproduce it. [less ▲]

Detailed reference viewed: 29 (8 ULg)
Peer Reviewed
See detailModulation of the lipopeptide pattern secreted by Bacillus subtilis upon colonization of different plant roots
Ongena, Marc ULg; Cawoy, H.; Margiassi, M. et al

Conference (2010)

Detailed reference viewed: 21 (3 ULg)
Full Text
Peer Reviewed
See detailModulation of the lipopeptide pattern secreted by Bacillus subtilis upon colonization of different plant roots
Ongena, Marc ULg; Cawoy, Hélène ULg; Smargiassi, Maïté et al

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2012), 78

Detailed reference viewed: 43 (22 ULg)
Peer Reviewed
See detailModulation of the radiosensitizing effect of (E)-24-deoxy-(fluoromethylene)cytidine (FMdC)by thymide analogues AZT, D4T and idUrd.
COUCKE, Philippe ULg; Cottin, E; Li, Y-X et al

in Radiotherapy & Oncology (1997), 43(supp 2), 13

Detailed reference viewed: 16 (4 ULg)
Full Text
Peer Reviewed
See detailModulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients
Weekers, Laurent ULg; Bouhanick, B.; Hadjadj, S. et al

in Diabetes (2005), 54(10), 2961-2967

ACE inhibition protects kidney function, but ACE insertion/ deletion (LID) polymorphism affects renal prognosis in type 1 diabetic patients'. ACE genotype may influence the renal benefits of ACE ... [more ▼]

ACE inhibition protects kidney function, but ACE insertion/ deletion (LID) polymorphism affects renal prognosis in type 1 diabetic patients'. ACE genotype may influence the renal benefits of ACE inhibition. We studied the impact of ACE 1/D polymorphism on the renal hemodynamic changes induced by ACE inhibition in type 1 diabetes. We studied renal hemodynamics (glomerular filtration rate [GFR], effective renal plasma flow [ERPF], filtration fraction [GFR/ERPF], mean arterial pressure [MAP], and total renal resistances [MAP/ ERPF]) repeatedly during normoglycemia, and then hyperglycemia in 12 normotensive, normoalbuminuric type 1 diabetes and the 11 genotype (associated with nephrorotection) versus 22 age- and sex-matched subjects with the ACE D allele after three randomly allocated 2- to 6-week periods on placebo, 1.25 mg/day ramipril, and 5.mg/day ramipril in A double-blind, cross-over study. During normoglycemia, the hemodynamic changes induced by ramipril were similar in both genotypes. During hyperglycemia, the changes induced by ramipril were accentuated in the 11 genotype group and attenuated dose dependently in the D allele group (treatment-genotype interaction P values for ERPF, 0.018; MAP 0.018; and total renal resistances, 0.0.55). These results provide a basis to. different renal responses to ACE inbibition according to ACE genotype in type 1 diabetes. [less ▲]

Detailed reference viewed: 18 (4 ULg)
Peer Reviewed
See detailModulation of tolerance to the GABA-sub(A) agonist THIP by environmental cues
Jodogne, C.; Tirelli, Ezio ULg

in Behavioural Brain Research (1990), 36(1-2), 33-40

Detailed reference viewed: 13 (0 ULg)
Full Text
Peer Reviewed
See detailModulation of tumor cell-fibroblasts interactions by 2 extracellular-matrix glycoproteins - laminin and fibronectin.
Noël, Agnès ULg; Nusgens, Betty ULg; Foidart, Jean-Michel ULg et al

in Abstracts for the 18th Annual Meeting of the European Society for Dermatologic Research (1988)

Detailed reference viewed: 4 (1 ULg)
Full Text
Peer Reviewed
See detailModulation par le cycle cellulaire de l'implantation des cellules souches hématopoïétiques
Gothot, André ULg; Giet, Olivier ULg; Huygen, S. et al

in Hématologie (2002), 8

Detailed reference viewed: 23 (7 ULg)
See detailModulations histaminiques des fonctions leucocytaires de l'homme
Bury, Thierry ULg

Doctoral thesis (1992)

Detailed reference viewed: 3 (0 ULg)
See detailModulations in the cerebral correlates underlying cognitive performance.
Schmidt, Christina ULg

Scientific conference (2012)

Detailed reference viewed: 8 (0 ULg)
Full Text
Peer Reviewed
See detailModulatory activities of Agelanthus dodoneifolius (Loranthaceae) extracts on stimulated equine neutrophils and myeloperoxidase activity
Boly, Rainatou; Dessy, Stephanie; Kohnen, Stephan et al

in International Journal of Molecular Medicine (2011), 28

Detailed reference viewed: 38 (4 ULg)