Sujets « métaboliquement sains », bien qu’obèses. Première partie: diagnostic, physiopathologie et prévalence

in Obésité (2009), 3

Around 30 to 50% of obese subjects are “metabolically normal” (MHO) whereas numerous nonobese subjects are “metabolically abnormal”. The distribution and function of adipose deposits seem to play a ... [more ▼]

Around 30 to 50% of obese subjects are “metabolically normal” (MHO) whereas numerous nonobese subjects are “metabolically abnormal”. The distribution and function of adipose deposits seem to play a crucial role in explaining this apparent paradox. The aim of this first article is to describe the clinical and biological characteristics that lead to the diagnosis of MHO, attempt to discover the etiopathogenesis of this syndrome and analyze the underlying pathophysiological mechanisms and, finally, to assess the prevalence of the MHO phenotype, which may vary according to the definition used and the population studied. [less ▲]

Sul mio corpo. La circoncisione femminile in un'analisi di contesto.

Book published by Interscienze (2010)

Un viaggio nelle dinamiche dell'esistenza delle donne di Luxor, all'interno del loro contesto sociale, vissuto da un'osservatrice partecipe, un corpo tra corpi, attraverso uno sguardo quanto più possibile ... [more ▼]

Un viaggio nelle dinamiche dell'esistenza delle donne di Luxor, all'interno del loro contesto sociale, vissuto da un'osservatrice partecipe, un corpo tra corpi, attraverso uno sguardo quanto più possibile scevro di giudizi precostituiti, che non giustifichi e non condanni, percorrendo una strada spesso accidentata con l'intento di transitare nella vita della gente, per comprenderne le diverse realtà. L'autrice si pone con senso critico di fronte al difficile tema della circoncisione femminile con l'intento di scoprire e capire, descrivendo in questo testo la propria esperienza diretta, aiutata dal supporto teorico fornito dalla letteratura disponibile sull'argomento e sugli aspetti religiosi e culturali a esso strettamente legati. Una lettura destinata ad antropologi, sociologi, etnologi, cultori della materia e a quanti, sebbene non dotati degli strumenti tecnici utili a facilitare la comprensione di tali problematiche in un'ottica scientifica, siano interessati all'argomento o desiderino accrescere le proprie capacità analitiche, critiche e di contestualizzazione, nonché di sensibilità nei confronti di punti di vista anche molto distanti. [less ▲]

Les sulfamidés diurétiques : des origines aux perspectives d'avenir

in Chimie Nouvelle (1990), 8

Sulfonated silica/carbon nanocomposites as novel catalysts for hydrolysis of cellulose to glucose

in Green Chemistry (2010), 12

Sulfonated silica/carbon nanocomposites were successfully developed as reusable, solid acid catalysts for the hydrolytic degradation of cellulose into high yields of glucose.

Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons.

in Neuroscience (1996), 71(3), 709-19

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium ... [more ▼]

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium pump (Na+/K+ ATPase), causing increased intracellular levels of Na+. Patch pipettes were used to introduce Na+ (40 mM in pipette solutions) into dopamine neurons in the rat midbrain slice in order to study the electrophysiological effects of increased intracellular Na+. We found that intracellular Na+ loading evoked 100-300 pA of outward current (at -60 mV) and increased whole-cell conductance; these effects developed gradually during the first 10 min after rupture of the membrane patch. Extracellular Ba2+ reduced most of the outward current evoked by Na+ loading; this Ba(2+)-sensitive current reversed direction at the expected reversal potential for K+ (EK), and was also blocked by extracellular tetraethylammonium (30 mM) and intracellular Cs+ (which replaced K+ in pipette solutions). The sulfonylurea drugs glipizide (IC50 = 4.9 nM), tolbutamide (IC50 = 23 microM) and glibenclamide (1 microM) were as effective as 300 microM Ba2+ in reducing the K+ current evoked by Na+ loading. When recording with "control" pipettes containing 15 mM Na+, diazoxide (300 microM) increased chord conductance and evoked outward current at -60 mV, which also reversed direction near EK. Effects of diazoxide were blocked by glibenclamide (1 microM) or glipizide (300 nM). Diazoxide (300 microM) and baclofen (3 microM), which also evoked K(+)-mediated outward currents recorded with control pipettes, caused little additional increases in outward currents during Na+ loading. Raising ATP concentrations to 10 mM in pipette solutions failed to significantly reduce currents evoked by diazoxide or Na+ loading, suggesting that these currents may not be mediated by ATP-sensitive K+ channels. Finally, Na+ loading using pipettes containing Cs+ in place of K+ evoked a relatively small outward current (50-150 pA at -60 mV), which developed gradually over the first 10 min after rupturing the membrane patch. This current was reduced by dihydro-ouabain (3 microM) and a low extracellular concentration of K+ (0.5 mM instead of 2.5 mM), but was not affected by Ba2+. We conclude that intracellular Na+ loading evokes a current generated by Na+/K+ ATPase in addition to sulfonylurea-sensitive K+ current. This Na(+)-dependent K+ current is unusual in its sensitivity to sulfonylureas, and could protect dopamine neurons against toxic effects of intracellular Na+ accumulation. [less ▲]

Sulla sua ultima nave Salgari imbarca Capitan Ferrero

in domani.arcoiris.tv (letteratura) a cura di Maurizio Chierici (2011)

Sulle tracce di un Pinocchio "futurista" : La variante Pinocchietto alla Guerra europea

in Van Den Bossche, Bart; Van den Bergh, Carmen; Manica, Giuseppe (Eds.) Azione/reazione : Il futurismo in Belgio e in Europa (2012)

Sulphur Emissions and Productivity Growth in Industrialised Countries

in Annals of Public and Cooperative Economics = Annales de l'Economie Publique, Sociale et Coopérative (2005), 76(2), 275-300

In this paper, we examine the relationship between economic and environmental performance. More specifically, we analyse the impact of SO2 reduction in the eighties (1980-1992) on productivity growth ... [more ▼]

In this paper, we examine the relationship between economic and environmental performance. More specifically, we analyse the impact of SO2 reduction in the eighties (1980-1992) on productivity growth, technical efficiency and technological progress for a set of 12 OECD countries. Our timeframe roughly corresponds to the adoption and implementation of the First Sulphur Protocol signed in 1985. First, we estimate an output based Malmquist productivity index using distance functions derived from successive DEA (Data Envelopment Analysis) frontiers. This index is decomposed in two components namely technical and efficiency change. Second, we regress the change in productivity and its two components on a set of explanatory variables including annual variations in SO2 emissions. The results indicate that reductions in SO2 do not seem to have had a significant impact on productivity growth. The decomposition into efficiency and technology changes suggests that two countervailing effects may explain this result. On one hand, SO2 cutbacks adversely affect efficiency but on the other hand, they stimulate technical change. [less ▲]

Sum-frequency generation characterisation of methanol, pentadecanoïc acid and water interfaces

Poster (2000, May)

Sum-frequency generation characterisation of the water/polyethylene glycol interface

Poster (2001, May)