Suivi scientifique projet Life Nature: réalisation de travaux de recherche consistant en l’évaluation des aménagements de gestion de l’habitat sur les populations de tétras lyre en Hautes-Fagnes.

Report (2007)

Sujet et objet dans le processus de recherche: le cas de l'entretien semi-directif

in Psychologika Themata (1990), 3(3), 175-182

Sujets de poids normal «métaboliquement obèses» et sujets obèses «métaboliquement sains»

in Revue Médicale de la Suisse Romande (2009), 5

Les relations entre poids corporel et anomalies métaboliques ne sont pas univoques. Ainsi, il existe des personnes non obèses métaboliquement anormales (MONW), rarement dépistées en raison d’un poids ... [more ▼]

Les relations entre poids corporel et anomalies métaboliques ne sont pas univoques. Ainsi, il existe des personnes non obèses métaboliquement anormales (MONW), rarement dépistées en raison d’un poids corporel faussement rassurant, et, à l’inverse, des sujets métaboliquement sains bien qu’ils soient obè ses (MHO). La topographie (intra-abdominale/hépatique vs sous-cutanée périphérique) et l’activité hormono-métabolique et pro-inflammatoire différente des dépôts graisseux semblent jouer un rôle déterminant pour expliquer ce paradoxe. Cet article de revue vise à décrire les grands principes de la prise en charge thérapeutique des personnes MONW, dans le but de réduire le risque accru de diabète de type 2 et de maladies cardiovasculaires, et de discuter les avantages et inconvénients d’une prise en charge classique de l’obésité chez les patients MHO. [less ▲]

Sujets « métaboliquement obèses » de poids normal. Première partie: diagnostic, physiopathologie et prévalence

in Obésité (2008), 3(3), 184-193

Obesity, particularly abdominal obesity, is the main risk factor for metabolic syndrome. However, some non-obese individuals are metabolically abnormal and therefore probably have an increased risk of ... [more ▼]

Obesity, particularly abdominal obesity, is the main risk factor for metabolic syndrome. However, some non-obese individuals are metabolically abnormal and therefore probably have an increased risk of cardiovascular disease. The present review paper aims to describe the main characteristics of the metabolically obese normal-weight (MONW) syndrome, analyse its etiopathogenesis and pathophysiology and, finally, assess its prevalence in various populations. [less ▲]

Sujets « métaboliquement sains », bien qu’obèses. Première partie: diagnostic, physiopathologie et prévalence

in Obésité (2009), 3

Around 30 to 50% of obese subjects are “metabolically normal” (MHO) whereas numerous nonobese subjects are “metabolically abnormal”. The distribution and function of adipose deposits seem to play a ... [more ▼]

Around 30 to 50% of obese subjects are “metabolically normal” (MHO) whereas numerous nonobese subjects are “metabolically abnormal”. The distribution and function of adipose deposits seem to play a crucial role in explaining this apparent paradox. The aim of this first article is to describe the clinical and biological characteristics that lead to the diagnosis of MHO, attempt to discover the etiopathogenesis of this syndrome and analyze the underlying pathophysiological mechanisms and, finally, to assess the prevalence of the MHO phenotype, which may vary according to the definition used and the population studied. [less ▲]

Sul mio corpo. La circoncisione femminile in un'analisi di contesto.

Book published by Interscienze (2010)

Un viaggio nelle dinamiche dell'esistenza delle donne di Luxor, all'interno del loro contesto sociale, vissuto da un'osservatrice partecipe, un corpo tra corpi, attraverso uno sguardo quanto più possibile ... [more ▼]

Un viaggio nelle dinamiche dell'esistenza delle donne di Luxor, all'interno del loro contesto sociale, vissuto da un'osservatrice partecipe, un corpo tra corpi, attraverso uno sguardo quanto più possibile scevro di giudizi precostituiti, che non giustifichi e non condanni, percorrendo una strada spesso accidentata con l'intento di transitare nella vita della gente, per comprenderne le diverse realtà. L'autrice si pone con senso critico di fronte al difficile tema della circoncisione femminile con l'intento di scoprire e capire, descrivendo in questo testo la propria esperienza diretta, aiutata dal supporto teorico fornito dalla letteratura disponibile sull'argomento e sugli aspetti religiosi e culturali a esso strettamente legati. Una lettura destinata ad antropologi, sociologi, etnologi, cultori della materia e a quanti, sebbene non dotati degli strumenti tecnici utili a facilitare la comprensione di tali problematiche in un'ottica scientifica, siano interessati all'argomento o desiderino accrescere le proprie capacità analitiche, critiche e di contestualizzazione, nonché di sensibilità nei confronti di punti di vista anche molto distanti. [less ▲]

Les sulfamidés diurétiques : des origines aux perspectives d'avenir

in Chimie Nouvelle (1990), 8

Sulfonated silica/carbon nanocomposites as novel catalysts for hydrolysis of cellulose to glucose

in Green Chemistry (2010), 12

Sulfonated silica/carbon nanocomposites were successfully developed as reusable, solid acid catalysts for the hydrolytic degradation of cellulose into high yields of glucose.

Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons.

in Neuroscience (1996), 71(3), 709-19

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium ... [more ▼]

In Parkinson's disease, there is evidence of impaired mitochondrial function which reduces the capacity to synthesize ATP in dopamine neurons. This would be expected to reduce the activity of the sodium pump (Na+/K+ ATPase), causing increased intracellular levels of Na+. Patch pipettes were used to introduce Na+ (40 mM in pipette solutions) into dopamine neurons in the rat midbrain slice in order to study the electrophysiological effects of increased intracellular Na+. We found that intracellular Na+ loading evoked 100-300 pA of outward current (at -60 mV) and increased whole-cell conductance; these effects developed gradually during the first 10 min after rupture of the membrane patch. Extracellular Ba2+ reduced most of the outward current evoked by Na+ loading; this Ba(2+)-sensitive current reversed direction at the expected reversal potential for K+ (EK), and was also blocked by extracellular tetraethylammonium (30 mM) and intracellular Cs+ (which replaced K+ in pipette solutions). The sulfonylurea drugs glipizide (IC50 = 4.9 nM), tolbutamide (IC50 = 23 microM) and glibenclamide (1 microM) were as effective as 300 microM Ba2+ in reducing the K+ current evoked by Na+ loading. When recording with "control" pipettes containing 15 mM Na+, diazoxide (300 microM) increased chord conductance and evoked outward current at -60 mV, which also reversed direction near EK. Effects of diazoxide were blocked by glibenclamide (1 microM) or glipizide (300 nM). Diazoxide (300 microM) and baclofen (3 microM), which also evoked K(+)-mediated outward currents recorded with control pipettes, caused little additional increases in outward currents during Na+ loading. Raising ATP concentrations to 10 mM in pipette solutions failed to significantly reduce currents evoked by diazoxide or Na+ loading, suggesting that these currents may not be mediated by ATP-sensitive K+ channels. Finally, Na+ loading using pipettes containing Cs+ in place of K+ evoked a relatively small outward current (50-150 pA at -60 mV), which developed gradually over the first 10 min after rupturing the membrane patch. This current was reduced by dihydro-ouabain (3 microM) and a low extracellular concentration of K+ (0.5 mM instead of 2.5 mM), but was not affected by Ba2+. We conclude that intracellular Na+ loading evokes a current generated by Na+/K+ ATPase in addition to sulfonylurea-sensitive K+ current. This Na(+)-dependent K+ current is unusual in its sensitivity to sulfonylureas, and could protect dopamine neurons against toxic effects of intracellular Na+ accumulation. [less ▲]

Sulla sua ultima nave Salgari imbarca Capitan Ferrero

in domani.arcoiris.tv (letteratura) a cura di Maurizio Chierici (2011)