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See detailLe macrobenthos de substrats meubles en zone infralittorale Corse - Indice et méthodologie adaptée pour un diagnostic écologique facilité
Donnay, Annick ULg

Doctoral thesis (2016)

At the time where the safeguarding and the conservation of the environment are a need for the Man, various ecological quality indicators are currently followed to evaluate the human influences; among ... [more ▼]

At the time where the safeguarding and the conservation of the environment are a need for the Man, various ecological quality indicators are currently followed to evaluate the human influences; among those the soft-bottom macrofauna. On the basis of some of their characteristics, the calculation of various biotic indices makes possible to qualify the meadow. However, before this qualification, the analysis of the macrobenthos is long and tedious. Two problems involved in their study exist: 1. In Corsica, the classically calculated biotic indices do not give an account of the existence of impacted settlements in oligotrophic coastal area and subjected to weak human influences. 2. The length of their study related to the difficulty of identification prevented a prompt response to the decision makers. To solve these problems, the adaptation of the calculation of a biotic index to the Corsican environmental conditions as well as the means of limiting the length of studies of the soft-bottom macrobenthos is required. For the adaptation of an index and to give an account of the natural variability of the settlements, eight habitats linked with settlements were defined around Corsica. Then, the J’MAMBI, based on the polluo-sensitivity of species, the richness, the diversity of the settlements and their equitability was developed, with references of good and bad ecological conditions for each habitats type. The application of this index makes possible to highlight fine variations in ecological qualities. To facilitate the identification and to decrease the time of soft-bottom macrobenthos’ study, the principle of taxonomic sufficiency is applied to the J’MAMBI. This principle makes possible to bring to the decision makers and to managers of such environmental studies, a facility diagnosis and a prompt response. Around the island, the identification at the "family" level is sufficient to give an account of ecological quality definite by a work to the "species" level. Thanks to "Benthic Methodology Simplification" or BeMSi, coupling the J’MAMBI and the facilitated identification, the two posed problems were solved. The utility of this methodology was put ahead within the framework of fish-farming survey, of outfall survey, of bay survey. Its sensitivity is also sufficient compared to other indices based on other indicators like the posidonia. Thank to this study, two types of research are possible: • The fundamental research grouping the "species" level identification and the J’MAMBI in order to improve the specific knowledge of microbenthic settlements and their reaction under or without disturbances. • The applied research using the BeMSi in order to obtain a general overview of the ecological quality status of an area and to help with decision making. In the future, it would be interesting to apply the results of this thesis to long temporal series of data and to other geographical areas in order to confirm the robustness of the index and the methodology developed. [less ▲]

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See detailMacrocyle-embedded b-lactams as novel inhibitors of the Penicillin Binding Protein PBP2a from MRSA
Dive, Georges ULg; Bouillon, Camille; Sliwa, Aline et al

in European Journal of Medicinal Chemistry (2013), 64

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See detailMacroecological patterns of genetic structure and diversity in the aquatic moss Platyhypnidium riparioides
Hutsemekers, Virginie ULg; Hardy, O. J.; Mardulyn, P. et al

in New Phytologist (2010)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Ageing Society
Artige, Lionel ULg

Conference (2016, March 10)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Aging Society
Artige, Lionel ULg

Conference (2014, May 16)

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See detailThe Macroeconomics of PAYG Pension Schemes in an Aging Society
Artige, Lionel ULg; Cavenaile, Laurent; Pestieau, Pierre ULg

E-print/Working paper (2014)

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See detailMacroéconomie du secteur culturel : ce que disent les chiffres
Mertens de Wilmars, Sybille ULg

Conference given outside the academic context (2010)

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See detailMacroevolution in early eukaryotes
Javaux, Emmanuelle ULg

Conference (2011, April 04)

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See detailMacroevolution in early eukaryotes
Javaux, Emmanuelle ULg

Scientific conference (2011)

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See detailMacroevolution in early eukaryotes
Javaux, Emmanuelle ULg

Conference (2011, October 21)

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See detailMacroevolution of Specificity in Cyanolichens of the Genus Peltigera Section Polydactylon (Lecanoromycetes, Ascomycota)
Magain, Nicolas ULg; Miadlikoswka, Jolanta; Goffinet, Bernard et al

in Systematic Biology (2017), 66(1), 74-99

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See detailMacroevolutionary analysis of the tempo of diversification in snappers and fusiliers (Percomorpha: Lutjanidae)
Frederich, Bruno ULg; Santini, Francesco

in Belgian Journal of Zoology (2017), 147(1), 17-35

The percomorph fish family Lutjanidae (snappers and fusiliers) includes about 135 reef-dwelling species, mainly confined to tropical and subtropical marine waters. The great majority of snappers are ... [more ▼]

The percomorph fish family Lutjanidae (snappers and fusiliers) includes about 135 reef-dwelling species, mainly confined to tropical and subtropical marine waters. The great majority of snappers are active predators feeding on fishes or crustaceans, even though some species, including the fusiliers (Caesioninae), have evolved zooplanktivory. Lutjanids show a great diversity of habitat preferences, based on depth segregation and distribution across reef and associated habitats (e.g. mangroves, seagrass beds, estuaries). In spite of their great ecological and economic importance little is known about the tempo of evolution in this group. The present study provides the most comprehensive molecular phylogeny to date for lutjanids, including 70% of extant species and 19 of the 21 currently described genera. We time-calibrated our molecular tree using the oldest described lutjanid fossils, and show how this group likely originated during the Late Cretaceous to Early Paleocene. Lutjanids experienced significant radiation during the Late Eocene and Early Oligocene, in contrast to a pattern of Late Oligocene/Miocene radiation observed in many other reef-associated groups. The time-tree allows us to investigate the tempo of diversification, and our results suggest a variation in the rate of speciation during the evolution of the major clade formed by “lutjanins and caesionins”. Variation in diet and life history strategies could explain this clade-specific dynamic, even though future phylogenetic comparative studies combining additional ecological and morphological data are needed to test this hypothesis. [less ▲]

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See detailMacroevolutionary patterns in sea breams, emperors and allies (Sparoidea, Acanthomorpha)
Santini, Francesco; Olivier, Damien ULg; Frederich, Bruno ULg

Poster (2017, January 07)

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See detailMacrofagos e factor a de necrose tumoral na necrolise epidermica toxica
Paquet, Philippe ULg; Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg et al

in Arquivos de Dermatologia (1995), 2

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular ... [more ▼]

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular inflamatorio varió dependiendo del estado de la enfermedad. La principal característica constante fue la importante implicación de la línea monocito-macrófago, incluyendo dendrocitos factor XIIIa+ HLA-DR+ y macrófagos CD68+ Mac 387+, antes y durante la necrosis epidérmica. El número de linfocitos CD4+ y CD8+ era comparativamente reducido. Ello se asociaba con un denso marcaje para el factor de necrosis tumoral alfa en la epidermis. CONCLUSIONES: Las células de estirpe monocito-macrófago superan en nùmero ampliamente a los linfocitos en las lesiones de la necrólisis epidérmica tóxica. El factor de necrosis tumoral alfa es problablemente una de las citocinas principales responsables de la necrosis. [less ▲]

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See detailMacrofagos y factor de necrosis tumoral alfa en la necrolisis epidermica toxica
Paquet, Philippe ULg; Nikkels, Arjen ULg; Arrese Estrada, Jorge ULg et al

in Archives of Dermatology (1994), 5

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular ... [more ▼]

ANTECEDENTES: Estudiamos las características inmunopatològicas de 5 casos de necrólisis epidérmica tóxica utilizando un amplio panel de anticuerpos. OSERVACIONES: El patrón y grado del infiltrado celular inflamatorio varió dependiendo del estado de la enfermedad. La principal característica constante fue la importante implicación de la línea monocito-macrófago, incluyendo dendrocitos factor XIIIa+ HLA-DR+ y macrófagos CD68+ Mac 387+, antes y durante la necrosis epidérmica. El número de linfocitos CD4+ y CD8+ era comparativamente reducido. Ello se asociaba con un denso marcaje para el factor de necrosis tumoral alfa en la epidermis. CONCLUSIONES: Las células de estirpe monocito-macrófago superan en nùmero ampliamente a los linfocitos en las lesiones de la necrólisis epidérmica tóxica. El factor de necrosis tumoral alfa es problablemente una de las citocinas principales responsables de la necrosis. [less ▲]

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See detailMacrofauna, rock magnetism and sedimentology in the Etroeungt Limestone (‘Strunian’, Uppermost Famennian) at Avesnelles (northern France)
Hubert, B.L. M.; Devleeschouwer, X.; Mistiaen, B. et al

in Whalen, M. (Ed.) Programme with Abstracts (2013)

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See detailMacroH2A histone variants maintain nuclear organization and heterochromatin architecture.
Douet, Julien; Corujo, David; Malinverni, Roberto et al

in Journal of Cell Science (2017)

Genetic loss-of-function studies in development, cancer and somatic cell reprogramming have suggested that the group of macroH2A histone variants might function through stabilizing the differentiated ... [more ▼]

Genetic loss-of-function studies in development, cancer and somatic cell reprogramming have suggested that the group of macroH2A histone variants might function through stabilizing the differentiated state by a yet unknown mechanism. Here, we present results demonstrating that macroH2A variants have a major function in maintaining nuclear organization and heterochromatin architecture. Specifically, we find that a substantial amount of macroH2A is associated with heterochromatic repeat sequences. We further identify macroH2A on sites of interstitial heterochromatin decorated by H3K9me3. Loss of macroH2A leads to major defects in nuclear organization including reduced nuclear circularity, disruption of nucleoli and a global loss of dense heterochromatin. Domains formed by repeat sequences when depleted of macroH2A are disorganized, expanded and fragmented and mildly re-expressed. On the molecular level we find that macroH2A is required for the interaction of repeat sequences with the nucleostructural protein Lamin B1. Taken together our results argue that a major function of macroH2A histone variants is to link nucleosome composition to higher order chromatin architecture. [less ▲]

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See detailMacroH2A in stem cells: a story beyond gene repression.
Creppe, Catherine ULg; Posavec, Melanija; Douet, Julien et al

in Epigenomics (2012), 4(2), 221-7

The importance of epigenetic mechanisms is most clearly illustrated during early development when a totipotent cell goes through multiple cell fate transitions to form the many different cell types and ... [more ▼]

The importance of epigenetic mechanisms is most clearly illustrated during early development when a totipotent cell goes through multiple cell fate transitions to form the many different cell types and tissues that constitute the embryo and the adult. The exchange of a canonical H2A histone for the 'repressive' macroH2A variant is one of the most striking epigenetic chromatin alterations that can occur at the level of the nucleosome. Here, we discuss recent data on macroH2A in zebrafish and mouse embryos, in embryonic and adult stem cells and also in nuclear reprogramming. We highlight the role of macroH2A in the establishment and maintenance of differentiated states and we discuss its still poorly recognized function in transcriptional activation. [less ▲]

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See detailMacroH2A regulates the commitment of adult and embryonic stem cells to differentation
Creppe, Catherine ULg; Cantariño, N; Janich, P et al

Poster (2011)

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