SUGAR: resultats d'une etude observationnelle belge concernant l'utilisation de la sitagliptine chez des patients diabetiques de type 2.

in Revue Médicale de Liège (2010), 65(3), 127-32

Sitagliptin (Januvia), the first selective inhibitor of dipeptidylpeptidase-4, has been assessed in a large Belgian prospective observational study. The aim of the SUGAR study was to evaluate the efficacy ... [more ▼]

Sitagliptin (Januvia), the first selective inhibitor of dipeptidylpeptidase-4, has been assessed in a large Belgian prospective observational study. The aim of the SUGAR study was to evaluate the efficacy of sitagliptin, at a dose of 100 mg once daily, when it was added in patients with uncontrolled type 2 diabetes followed in real life conditions. In the intent-to-treat population (n = 605), mean glycated haemoglobin level decreased from 8.41 +/- 1.18% to 7.29 +/- 0.86% after a follow up averaging 110 days (p < 0.0001). Similarly, mean fasting plasma glucose level decreased from 180 +/- 50 mg/dl to 141 +/- 37 mg/ dl (p < 0.0001). The improvement of these two parameters was observed independently of basal demographic characteristics, but was directly influenced by baseline initial corresponding values. The vast majority of patients included in SUGAR were initially treated by metformin as monotherapy (current criterion for sitagliptin reimbursement in Belgium); metformin daily dose slightly decreased when sitagliptin was added (from 1975 +/- 681 mg to 1919 +/- 667 mg; p = 0.033). Patients receiving other glucose-lowering agents, as single or combined therapies, had also a significant alleviation of their treatment when sitagliptin was added. After 3-6 months of follow up, more than 95% of patients still received sitagliptin, arguing for both the efficacy and the good tolerance of this new oral antidiabetic agent in clinical practice. [less ▲]

Suggested french translations of expressions in the field of operant conditioning

in Journal of the Experimental Analysis of Behavior (1960), 3(2), 167-170

Suggested mechanism of action of classical and deformable liposomes through pig ear skin

Conference (2010, April 09)

Suggestions for improving continuity of medication between hospital and home in a local context of Wallonia

Conference (2012, October 20)

Background: Unjustified modifications of the patient’s usual medication during his hospitalisation induce various problems for the patient (confusion, additional costs) and for healthcare professionals ... [more ▼]

Background: Unjustified modifications of the patient’s usual medication during his hospitalisation induce various problems for the patient (confusion, additional costs) and for healthcare professionals (work overload, additional cost). The principle of favouring dialogue between local actors to reach commonly accepted solutions (KCE, 2010) was used in the current study. Research question: Which local strategies could be implemented to improve continuity of drug therapy when the patient moves to hospital or back home? Method: The study took place in Liège (Wallonia). Participants were recruited within four professional groups: general practitioners, hospital specialists, pharmacists and hospital stakeholders. First, a nominal group was carried out for each professional group. Prioritized suggestions were obtained. In a second phase, Delphi method was used. Suggestions from the nominal group were submitted to representatives of each profession (a total of 40) to evaluate relevance, acceptability and feasibility of each one. Results: A total of 101 suggestions were evoked in the first phase. They were related to two main themes: implication of well-defined actors and development of specific means. Five consensual suggestions emerged from the Delphi process: provision by the general practitioner of a complete list of medication on hospital admission; provision by the hospital specialist of a list of drugs at discharge; development of formal hospital processes to keep the patient’s usual medication; centralisation of medication data; development and use of a unique medical record. Conclusion: A link medium handled by the patient when he moves to the hospital and back home is the major idea mentioned and accepted by local actors. [less ▲]

Suggestions for new photoelectric observations of the zodiacal light and the counterglow

in L'étude optique de l'atmosphère terrestre : communications présentées au colloque international tenu à l'Institut d'Astrophysique de l'Université de Liège, les 3 et 4 septembre 1951 (1952)

«Sui manoscritti veneziani del Foucon de Candie»

in Bulletin Bibliographique de la Société Rencesvals (1997)

Suicidal behavior in depressive disorder: an event-related potential study.

in Biological Psychiatry (1996), 40(2), 116-22

P300 and contingent negative variation (CNV) were recorded in depressive inpatients with and without history of suicide attempt. The results showed a significant reduction of P200, P300, and CNV and a ... [more ▼]

P300 and contingent negative variation (CNV) were recorded in depressive inpatients with and without history of suicide attempt. The results showed a significant reduction of P200, P300, and CNV and a significant increase of postimperative negative variation (PINV) in patients who had attempted suicide compared to patients with a negative history. Moreover, P300 amplitude was negatively related with the Suicidal Risk and the Hopelessness but not with the Hamilton scales. These results stress the need to differentiate clinical subgroups of patients to assess the psychophysiology of depression, and indicate that patients who attempted suicide exhibit lower cortical resources and poorer cortical performance than patients without history of suicide attempt. [less ▲]

Suicide et événements de vie : ambiguïtés méthodologiques et psychothérapiques

in Psychologie Médicale (1988), 20(3), 315-317

SUIT deliverable 4.2 - Internal report on the application of EIA to cultural heritage & Guillemins extended case study analysis

Report (2002)

This research was made under the SUIT European project and consisted of carrying out an extended case study analysis (the Guillemins station project in Liège, Belgium), through extensive monitoring and ... [more ▼]

This research was made under the SUIT European project and consisted of carrying out an extended case study analysis (the Guillemins station project in Liège, Belgium), through extensive monitoring and post-evaluation of the decision-making process, which was compared to the EIA directive as well as to the different stakeholders’ wishes and views. This task was mainly intended at providing transferable key lessons in order to fine-tune the future SUIT guidance on integrated EA procedure. [less ▲]

Suitability of bovine pregnancy-associated glycoprotein (bPAG-1) for early pregnancy diagnosis in cows

Poster (2005)

Determination of the earliest possible time for pregnancy detection via enzymelinked- immuno-sorbant-assay for bPAG-1 in dairy cows