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See detailReactivity of (R)-4-phenyloxazolidin-2-thione chiral auxiliary: from deprotection to heterocyclic interconversion
Monbaliu, Jean-Christophe ULg; Tinant, Bernard; Marchand-Brynaert, Jacqueline

in Heterocycles (2008), 75

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See detailReactivity of auranofin with selenols and thiols: implications for the anticancer activity of gold(I) compounds
Di Sarra, Francesca; Fresch, Barbara ULg; Bini, Riccardo et al

in European Journal of Inorganic Chemistry [=EurJIC] (2013), 2013(15), 2718

Detailed reference viewed: 18 (2 ULg)
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See detailReactivity of autoantibodies in systemic lupus erythematosus with synthetic core histone peptides.
Muller, S.; Bonnier, D.; Thiry, Marc ULg et al

in International Archives of Allergy and Applied Immunology (1989), 89(2-3), 288-96

The specificity of autoantibodies present in the serum of 151 patients with systemic lupus erythematosus (SLE) was investigated by ELISA using as antigen individual histones as well as 17 different core ... [more ▼]

The specificity of autoantibodies present in the serum of 151 patients with systemic lupus erythematosus (SLE) was investigated by ELISA using as antigen individual histones as well as 17 different core histone synthetic peptides. Many of the sera reacted with four terminal peptides (residues 1-21 and 130-135 of H3, 1-29 of H4 and 1-25 of H2B) while fewer reacted with internal peptides (residues 65-85 of H2A and 40-55 of H3). Of the 151 SLE sera, 88% reacted with one or more of the six core histone peptides whereas only 57% reacted with one or more of the complete core histone molecules. Antibodies to mononucleosomes from chicken erythrocytes were also prepared in rabbits. The rabbit antisera were tested by ELISA using as antigen chromatin subunits, native and denatured DNA, individual histones and 23 natural and synthetic peptides of histones. The antinucleosome antibodies were found to recognize the same peptide fragments as those recognized by the SLE sera. [less ▲]

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See detailReactivity of functional SAN toward coreactive EPR-g-MA at planar interface
Pagnoulle, Christophe; Moussaif, Noureddine; Riga, Joseph et al

in Journal of Polymer Science. Part A, Polymer Chemistry (2000), 38(19), 3682-3689

The grafting kinetics of reactive poly(styrene-co-acrylonitrile) (SAN) onto EPR-g-MA was studied under isothermal conditions, at the planar interface of an SAN/ethylene-propylene rubber (EPR) bilayer film ... [more ▼]

The grafting kinetics of reactive poly(styrene-co-acrylonitrile) (SAN) onto EPR-g-MA was studied under isothermal conditions, at the planar interface of an SAN/ethylene-propylene rubber (EPR) bilayer film in relation to the type of reactive groups, NH2 versus carbamate (which is an amine precursor), attached to SAN. The amount of SAN chemically bound to EPR chains at the interface was estimated by selectively washing off the unreacted SAN chains before X-ray photon spectroscopic analysis of the released surface. It is clear that the mutual reactivity of the reactive groups, i.e., the NH2-MA pair versus the carbamate-MA pair, has a decisive effect on the amount of SAN that reacts with EPR-g-MA at the interface. In case of SAN-carb, the grafting reaction is controlled by the thermolysis of the carbamate groups into primary amines. [less ▲]

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See detailReactivity of Halogenoethylene Ions using Photoionization and Collisional Activation.
Leyh, Bernard ULg; Hoxha, A.; Franck, B. et al

in Karjalainen, E. J.; Hesso, A. E.; Jalonen, J. E. (Eds.) et al Advances in Mass Spectrometry: Volume 14. (1998)

Unimolecular reactivity of ionized difluoroethylene and vinylbromide have been investigated using photoionization mass spectrometry and tandem mass spectrometry. Kinetic energy release distributions ... [more ▼]

Unimolecular reactivity of ionized difluoroethylene and vinylbromide have been investigated using photoionization mass spectrometry and tandem mass spectrometry. Kinetic energy release distributions corresponding to HF- and F- losses from 1,1-C2H2F2+ and to Br-loss from C2H3Br+ have been determined. At low internal energy the loss of HF from C2H2F2+ leads to the fluoroacetylene cation with a large kinetic energy release (0.4-2.5 eV) while at higher energy a new channel is opened, leading to C=CHF+ (fluorovinylidene) with a much smaller kinetic energy release (0.0-0.2 eV). For the F-loss from C2H2F2+ and the Br-loss from C2H3Br+ bimodal distributions have been observed. The possible role of excited states in these dissociations is discussed. [less ▲]

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See detailReactivity of human anti-alpha-galactosyl IgG antibody with alpha(1-->3)-linked galactosyl epitopes exposed on basement membranes and on glomerular epithelial cells: an in vitro and in vivo study in the mouse.
Vecchi, M. L.; Davin, J. C.; Castronovo, Vincenzo ULg et al

in Clinical & Experimental Immunology (1989), 78(2), 271-7

Anti-alpha-galactosyl antibody (a-Gal Ab) is a human natural antibody belonging to the IgG class, found in high titres in all normal sera regardless of blood group, and specifically recognizing alpha (1 ... [more ▼]

Anti-alpha-galactosyl antibody (a-Gal Ab) is a human natural antibody belonging to the IgG class, found in high titres in all normal sera regardless of blood group, and specifically recognizing alpha (1-->3)-linked galactosyl residues. We have observed by radioimmunoassay, ELISA, passive haemagglutination and immunofluorescence blocking studies that affinity-purified a-Gal Ab reacted with mouse laminin, but not with the other mouse basement membrane proteins tested; it was able to fix complement in vitro. When injected intravenously into mice, the a-Gal Ab was found to mainly accumulate in kidneys, liver, spleen and lungs. No acute respiratory distress syndrome was observed shortly after the i.v. injection of 100 or 200 microg of antibodies. These doses of a-Gal Ab were also unable to induce acute glomerular injury. However, in primary cultures, the a-Gal Ab (100 or 200 microg per ml of medium) was shown to impair the attachment of mouse glomerular epithelial cells to mouse laminin and to elicit complement-dependent cell damage. The data indicate that the a-Gal Ab can interact in vitro and/or in vivo with alpha (1-->3)-linked galactosyl residues exposed on murine laminin or on murine cultured glomerular epithelial cells. Although this antibody fails to be pathogenic when administered at low doses in the intact animal, similar doses can alter some metabolic properties of these cells in vitro. [less ▲]

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See detailReactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: what's wrong with these enzymes?
Josephine, Helen R.; Charlier, Paulette ULg; Davies, Christopher et al

in Biochemistry (2006), 45(51), 15873-83

Beta-lactams exert their antibiotic action through their inhibition of bacterial DD-peptidases (penicillin-binding proteins). Bacteria, in general, carry several such enzymes localized on the outside of ... [more ▼]

Beta-lactams exert their antibiotic action through their inhibition of bacterial DD-peptidases (penicillin-binding proteins). Bacteria, in general, carry several such enzymes localized on the outside of their cell membrane to catalyze the final step in cell wall (peptidoglycan) synthesis. They have been classified into two major groups, one of high molecular weight, the other of low. Members of the former group act as transpeptidases in vivo, and their inhibition by beta-lactams leads to cessation of bacterial growth. The latter group consists of DD-carboxypeptidases, and their inhibition by beta-lactams is generally not fatal to bacteria. We have previously shown that representatives of the former group are ineffective at catalyzing the hydrolysis/aminolysis of peptidoglycan-mimetic peptides in vitro [Anderson et al. (2003) Biochem. J. 373, 949-955]. The theme of these experiments is expanded in the present paper where we describe the synthesis of a series of beta-lactams (penicillins and cephalosporins) containing peptidoglycan-mimetic side chains and the kinetics of their inhibition of a panel of penicillin-binding proteins spanning the major classes (Escherichia coli PBP 2 and PBP 5, Streptococcus pneumoniae PBP 1b, PBP 2x and PBP 3, the Actinomadura R39 DD-peptidase, and the Streptomyces R61 DD-peptidase). The results of these experiments mirror and expand the previous results with peptides. Neither peptides nor beta-lactams with appropriate peptidoglycan-mimetic side chains react with the solubilized constructs of membrane-bound penicillin binding proteins (the first five enzymes above) at rates exceeding those of generic analogues. Such peptides and beta-lactams do react at greatly enhanced rates with certain soluble low molecular weight enzymes (R61 and R39 DD-peptidases). The former result is unexpected and interesting. Why do the majority of penicillin-binding proteins not recognize elements of local peptidoglycan structure? Possible answers are discussed. That this question needs to be asked casts fascinating shadows on current studies of penicillin-binding proteins for new drug design. [less ▲]

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See detailReactivity of precious metal and transition metal oxide catalysts towards the total oxidation of volatile organic compounds containing nitrogen or sulfur atom (N-VOCs or S-VOCs)
Cellier, Caroline; Ruaux, V.; Lahousse, C. et al

in Catalytic Combustion, volume 2 (2005, September)

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See detailReactivity towards singlet oxygen of propofol inside liposomes and neuronal cells
Heyne, Belinda; Brault, Daniel; Fontaine-Aupart, Marie-Pierre et al

in Biochimica et Biophysica Acta - General Subjects (2005), 1724

Singlet oxygen (1O2), a reactive oxygen species, has been found to be implicated in many cellular events and pathological disorders.Herein, we investigated the reactivity of 1O2 towards the anaesthetic ... [more ▼]

Singlet oxygen (1O2), a reactive oxygen species, has been found to be implicated in many cellular events and pathological disorders.Herein, we investigated the reactivity of 1O2 towards the anaesthetic agent propofol (PPF) encapsulated within DMPC liposomes. By time resolved luminescence, the rate constant of 1O2 quenching by PPF was evaluated, depending on the location of the sensitizer. The nature of the oxidation product, resulting from the reaction of 1O2 with PPF, was determined using absorption and HPLC techniques. Finally, the in vitro protective effect of PPF towards the1O2-induced neuronal cell toxicity was evaluated in terms of cell viability. [less ▲]

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See detailRéadaptation après lésion ligamentaire du genou
Croisier, Jean-Louis ULg

in Actes du Congrès Eurokiné 2003 (2003, April)

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See detailRéadaptation cognitive d'activités de vie quotidienne dans la maladie d'Alzheimer
Wojtasik, Vinciane ULg; Lekeu, Françoise ULg; Quittre, Anne ULg et al

in Gérontologie et Société : Cahiers de la Fondation Nationale de Gérontologie (2009), 130

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See detailReader zum Grundseminar Epoche "Empfindsamkeit"
Viehöver, Vera ULg

Learning material (2001)

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See detailReader zum Thematischen Proseminar "Goethes Sturm und Drang"
Viehöver, Vera ULg

Learning material (2000)

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See detailReading abilities in French speaking and Italian teenagers with Down's syndrome; A cross cultural study
Frenkel, Stéphanie ULg; Vicari, Stefano

Conference (2012, June)

Numerous studies have shown that phonological awareness plays an essential role in the acquisition of reading abilities in typically developing children. It has also been mentioned that the working memory ... [more ▼]

Numerous studies have shown that phonological awareness plays an essential role in the acquisition of reading abilities in typically developing children. It has also been mentioned that the working memory has a central role in the reading activity. Concerning Down’s syndrome individuals, they are impaired in two central factors in reading acquisition: phonological awareness and verbal STM storage. This was observed in comparison with typically developing participants of equivalent MA or with individuals with other developmental pathologies. However, Down syndrome individuals manage to learn to read. On the other hand, we note differences in age of mastering literacy according to the fundamental linguistic differences in orthographic depth. In fact, if children from a majority of European countries become accurate and fluent in foundation level reading before the end of the first school year, others do not. The effects appear not to be attributable to differences in age of starting or letter knowledge. The causes seem to be fundamental linguistic differences in syllabic complexity (which affect decoding) and fundamental linguistic differences in orthographic depth (which affect both word reading and non word reading). The time needed to establish foundation literacy is higher for French than for Italian language. It seems to be due to French language characteristics. The aim of the present study is to explore the effect of two different languages on the working memory and linguistic development in teenagers with Down’s syndrome. The comparison of two different linguistic samples of DS participants (French speakers and Italian speakers) may contribute to better understand the role played by different languages on the development of verbal working memory and phonological awareness. Aspects of reading, writing, working memory, STM memory and phonological awareness were assessed. This paper will present and discuss our results. [less ▲]

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See detailReading and the Information Explosion from the Past to the Future: Reflecting on the Example of François de La Mothe le Vayer
Decoster, Sara ULg

Conference (2011, October 15)

This paper deals with the 17th century information explosion and its influence on scholarly reading behaviour. The invention of the printing press had increased drastically the amount of books and at the ... [more ▼]

This paper deals with the 17th century information explosion and its influence on scholarly reading behaviour. The invention of the printing press had increased drastically the amount of books and at the same time, the volume of knowledge. As a result, it became very difficult for researchers to embrace the full account of available science. Starting from the work of the French libertine sceptic François de La Mothe le Vayer (1588 - 1672), the analysis will focus on two major questions of 17th century research: The first question “Is the immense profusion of books instructive or rather confusing?” will be the basis for a second one: “Hasn't everything been said? Is it still possible to add something to this colossal knowledge?” [less ▲]

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See detailReading disabilities in SLI and dyslexia result from distinct phonological impairments
Nithart, Christelle; Demont, Elisabeth; Majerus, Steve ULg et al

in Developmental Neuropsychology (2009), 34

Detailed reference viewed: 82 (18 ULg)
See detailReading for change : performance and engagement across countries : results of PISA 2000
Kirsch, I.; De Jong, J.; Lafontaine, Dominique ULg et al

Book published by OCDE (2003)

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See detailReading Pausanias: Cults of the Gods and Representation of the Divine
Pirenne-Delforge, Vinciane ULg

in Bremmer, Jan N.; Erskine, Andrew (Eds.) The Gods of Ancient Greece: Identities and Transformations (2010)

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See detailReading the decomposition chemistry of human remains with a new pair of glasses
Stefanuto, Pierre-Hugues ULg; Stadler, s; Perrault, K et al

in Hyphenated Techniques in Chromatography HTC-13 - Book of abstracts (2014, January)

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See detailReading the decomposition chemistry of human remains with a new pair of glasses
Stefanuto, Pierre-Hugues ULg; Stadler, Sonja; Perrault, Katelynn et al

Conference (2014, January)

Detailed reference viewed: 6 (0 ULg)