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See detailRadiotherapy : controversy
Beckers, Albert ULg

Scientific conference (2012, November)

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See detailRadiotherapy of choroidal metastases.
Rosset, A; Zografos, L; COUCKE, Philippe ULg et al

in Radiotherapy & Oncology (1998), 46(3), 263-268

Abstract Purpose: This retrospective study was undertaken to clarify the role of high energy external beam radiation therapy (EBRT) and to determine its safety and efficacy on local control and visual ... [more ▼]

Abstract Purpose: This retrospective study was undertaken to clarify the role of high energy external beam radiation therapy (EBRT) and to determine its safety and efficacy on local control and visual acuity in patients suffering from choroidal metastases (CM). Materials and methods: The records of 58 consecutive patients treated with EBRT between 1970 and 1993 were analyzed. The female to male ratio was 2.9 and the median age was 59 years (range 40–81 years). Thirty-six patients (62%) had unilateral CM and 22 patients had bilateral CM. The mean number of lesions per eye was two. Retinal detachment was present in 65% of cases. The primary tumour (PT) was breast carcinoma for 38 patients (75%), lung carcinoma for 10 patients (17%) and gastrointestinal, genitourinary or unknown PT for the remaining 10 patients. The median interval of time between the PT and the CM was 55 months (range 0–228 months). All patients were treated with megavoltage irradiation. The median prescribed dose was 35.5 Gy (range 20–53 Gy) normalized at a 2 Gy per fraction schedule with an a/b value of 10 Gy. Various techniques were used and whenever possible the lens was spared. Ten patients with unilateral disease were treated in both eyes. Results: The tumour response was slow. When assessed after 3 months or more, the complete response rate was 53% with significantly better results for doses higher than 35.5 Gy (72 versus 33%; P = 0.009). Visual acuity was improved or stabilized in 62% of patients, with also significantly better results when doses higher than 35.5 Gy (P = 0.014) were administered. Amongst 26 patients with unilateral CM who had no elective contralateral irradiation, three developed metastasis in the opposite eye versus none of the 10 patients who had bilateral irradiation. Five complications occurred (three cataracts, one retinopathy and one glaucoma). Conclusion: Radiation therapy is an efficient and safe palliative treatment for choroidal metastases and it helps the preservation of vision. Thus, there is a major impact on the quality of life in a group of patients with an almost uniformly fatal prognosis. Both tumour response and visual acuity are significantly improved if doses higher than 35.5 Gy are administered. Whenever possible, a lens sparing technique should be used. Ó 1998 Elsevier Science Ireland Ltd. [less ▲]

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See detailThe radius and mass of the close solar twin 18 Scorpii derived from asteroseismology and interferometry
Bazot, Michaël; Ireland, M. J.; Huber, D. et al

in Astronomy and Astrophysics (2011), 526

The growing interest in solar twins is motivated by the possibility of comparing them directly to the Sun. To carry on this kind of analysis, we need to know their physical characteristics with precision ... [more ▼]

The growing interest in solar twins is motivated by the possibility of comparing them directly to the Sun. To carry on this kind of analysis, we need to know their physical characteristics with precision. Our first objective is to use asteroseismology and interferometry on the brightest of them: 18 Sco. We observed the star during 12 nights with HARPS for seismology and used the PAVO beam-combiner at CHARA for interferometry. An average large frequency separation 134.4 ± 0.3 μHz and angular and linear radiuses of 0.6759 ± 0.0062 mas and 1.010 ± 0.009 Rsun were estimated. We used these values to derive the mass of the star, 1.02 ± 0.03 Msun. [less ▲]

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See detailRadoux (Familie)
Pirenne, Christophe ULg

in Finscher, Ludwig (Ed.) Die Musik in Geschichte und Gegenwart (in press)

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See detailRaes de Heers
Xhayet, Geneviève ULg

in Nouvelle biographie nationale tome 1 (1988)

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See detailRaes de Heers, un "Condottiere" liégeois du XVe siècle
Xhayet, Geneviève ULg

in Moyen Age (Le) (1987), 93

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See detailRafaella De Rosa, « Rethinking the Ontology of Cartesian Essences »
Dubouclez, Olivier ULg

in Bulletin cartésien (2013)

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See detailRagged N-Termini and Other Variants of Class a Beta-Lactamases Analysed by Chromatofocusing
Matagne, André ULg; Joris, Bernard ULg; Van Beeumen, J. et al

in Biochemical Journal (1991), 273(273), 503-10

Four beta-lactamases excreted by Gram-positive bacteria exhibited microheterogeneity when analysed by chromatofocusing or ion-exchange chromatography. Ragged N-termini were in part responsible for the ... [more ▼]

Four beta-lactamases excreted by Gram-positive bacteria exhibited microheterogeneity when analysed by chromatofocusing or ion-exchange chromatography. Ragged N-termini were in part responsible for the charge variants, but deamidation of an asparagine residue was also involved, at least for the Bacillus licheniformis enzyme. The activity of a contaminating proteinase could also be demonstrated in the case of Actinomadura R39 beta-lactamase. With that enzyme, proteolysis resulted in partial inactivation, but the inactivated fragments were easily separated from the active forms. With these, as with the other enzymes, the kinetic parameters of the major variants were identical with those of the mixture within the limits of experimental error, so that the catalytic properties of these enzymes can be determined with the 'heterogeneous' preparations. [less ▲]

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See detailRahier, de Jongh, Spirlet : souvenirs de famille
Donneau, Olivier ULg

in Olne, qualité de vie, qualité de village, Catalogue de l’exposition organisée à la Maison communale du 5 au 27 novembre 2005 (2005)

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See detailLe rail belge s'ouvre à la concurrence. Peut-on tirer parti de l'expérience étrangère ?
Gautier, Axel ULg

in Regards économiques (2004)

La Commission européenne vient de décider d’ouvrir d’ici 2010 l’ensemble du marché ferroviaire à la concurrence. À l’avenir, la SNCB ne sera plus la seule compagnie à transporter des passagers dans notre ... [more ▼]

La Commission européenne vient de décider d’ouvrir d’ici 2010 l’ensemble du marché ferroviaire à la concurrence. À l’avenir, la SNCB ne sera plus la seule compagnie à transporter des passagers dans notre pays. Dans ce numéro de Regards économiques, nous analysons au travers de l’expé- rience de deux pays, l’Allemagne et l’Angleterre, les conséquences de la libéralisation du secteur sur le rail belge. [less ▲]

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See detailRail-Road terminal locations: aggregation errors and best potential locations on large networks
Limbourg, Sabine ULg; Jourquin, Bart

in European Journal of Transport and Infrastructure Research (2007), 7(4), 317-334

In network location problems, the number of potential locations is often too large in order to find a solution in a reasonable computing time. That is why aggregation techniques are often used to reduce ... [more ▼]

In network location problems, the number of potential locations is often too large in order to find a solution in a reasonable computing time. That is why aggregation techniques are often used to reduce the number of nodes. This reduction of the size of the location problems makes them more computationally tractable, but aggregation introduces errors into the solutions. Some of these errors will be estimated in this paper. A method that helps to isolate the best potential locations for rail-road terminals embedded in a hub-and-spoke network will further be outlined. Hub location problems arise when it is desirable to consolidate flows at certain locations called hubs. The basic idea is to use the flows of commodities and their geographic spreading as input to determine a set of potential locations for hub terminals. The exercise will be done for the trans-European networks. These potential locations can then further be used as input by an optimal location method. [less ▲]

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See detailThe Rain in Spain: Report on the Salamanca American Poetry Conference
Delville, Michel ULg; Dworkin

in Jacket (2001)

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See detailThe Rain Ratio Hypothesis Revisited
Munhoven, Guy ULg

Poster (2012, September 21)

The Rain Ratio Hypothesis (Archer and Maier-Reimer, 1994, Nature 367, 260–263) ascribes an important part of the observed glacial-interglacial variations of CO2 in the atmosphere to reduced sea-floor rain ... [more ▼]

The Rain Ratio Hypothesis (Archer and Maier-Reimer, 1994, Nature 367, 260–263) ascribes an important part of the observed glacial-interglacial variations of CO2 in the atmosphere to reduced sea-floor rain ratio (i.e., carbonate-C/organic-C in the biogenic particle flux at the sea-floor) during glacial times. With a lower sea-floor rain ratio the influence of organic carbon respiration on carbonate dissolution is stronger. The deep-sea carbonate ion concentration required for global ocean carbonate compensation will then be higher, which in turn contributes to lower atmospheric pCO2. Munhoven (2007, Deep-Sea Research II, 722–746) showed that the suggested rain ratio reductions lead to unrealistic sedimentary records for %CaCO3: the transition zone changes in the model sedimentary record were too large and opposite in phase to available observational data. The rain ratio reduction applied by Munhoven (2007) was uniform over the ocean and the author hypothesised that a non-uniform reduction could change the complete picture. If the rain ratio variations had primarily taken place in open ocean areas of great depth—essentially in regions where the sea floor was deeper than the saturation horizon or the CCD—then the transition zone boundaries could possibly have moved less. Here, we test this hypothesis and analyse the effect of depth dependent variations. We find that concentrating rain ratio changes over areas of great water depth completely alters the sedimentary imprint: the phase relationship of the signal reverts (compared to the uniform case) and the amplitude of the change decreases, bringing it into better agreement with available observations. However, the global average rain ratio reduction of 40% that yielded a 40 ppm reduction of atmospheric pCO2 in the uniform case only leads to 25 ppm in this non-uniform case. [less ▲]

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See detailThe Rain Ratio Hypothesis: Can it be Rescued?
Munhoven, Guy ULg

Conference (2010, May 04)

The Rain Ratio Hypothesis (Archer and Maier-Reimer, 1994, Nature 367, 260–263) ascribes an important part of the observed glacial-interglacial variations of CO2 in the atmosphere to reduced sea-floor rain ... [more ▼]

The Rain Ratio Hypothesis (Archer and Maier-Reimer, 1994, Nature 367, 260–263) ascribes an important part of the observed glacial-interglacial variations of CO2 in the atmosphere to reduced sea-floor rain ratio (i.e., carbonate-C/organic-C in the biogenic particle flux at the sea-floor) during glacial times. With a lower sea-floor rain ratio the influence of organic carbon respiration on carbonate dissolution is stronger. The deep-sea carbonate ion concentration required for global ocean carbonate compensation will then be higher, which in turn contributes to lower atmospheric pCO2. Munhoven (2007, Deep-Sea Research II, 722–746) showed that the suggested rain ratio reductions lead to unrealistic sedimentary records for %CaCO3: the transition zone changes in the model sedimentary record were too large and opposite in phase to available observational data. The rain ratio reduction applied by Munhoven (2007) was uniform over the ocean and the author hypothesised that a non-uniform reduction could change the complete picture. If the rain ratio variations had primarily taken place in open ocean areas of great depth—essentially in regions where the sea floor was deeper than the saturation horizon or the CCD—then the transition zone boundaries could possibly have moved less. Here, we test this hypothesis and analyse the effect of depth dependent variations. It is shown that concentrating rain ratio changes over areas of greatest water depth completely alters the sedimentary imprint: the phase relationship of the signal reverts (compared to the uniform case) and the amplitude of the change decreases, bringing it into better agreement with the observations. However, the pCO2 response is also reduced. The global average rain ratio reduction of 40% that yielded a 40 ppm reduction of atmospheric pCO2 in the uniform case only leads to 25 ppm in this non-uniform case. Results for other depth-dependent reductions will also be discussed. [less ▲]

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