Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Peer Reviewed
See detailThe prenatal role of thyroid hormone evidenced by fetomaternal Pit-1 deficiency
de Zegher, F.; Pernasetti, F.; Vanhole, C. et al

in Journal of Clinical Endocrinology and Metabolism (1995), 80(11), 3127-30

The role of thyroid hormone in the human fetus is uncertain; a significant amount of T4 is transferred from the maternal to the fetal circulation. A mother-infant pair was found to be heterozygotic for a ... [more ▼]

The role of thyroid hormone in the human fetus is uncertain; a significant amount of T4 is transferred from the maternal to the fetal circulation. A mother-infant pair was found to be heterozygotic for a point mutation in codon 271 of the gene encoding Pit-1, a pituitary-specific transcription factor regulating somatotrope, lactotrope, and thyrotrope function. At birth, serum T4 was undetectable in mother and infant. The newborn presented with a striking delay of respiratory, cardiovascular, neurological, and bone maturation. Despite replacement therapy since birth, neurological development of the infant is impaired. Fetomaternal Pit-1 deficiency resulted in unmitigated fetal hypothyroidism that unmasked thyroid hormone as a potent endogenous drive of fetal maturation and revealed placental transfer of maternal T4 as a rescue mechanism for infants with congenital hypothyroidism, preventing fetal and neonatal symptoms of thyroid deficiency and safeguarding developmental potential. [less ▲]

Detailed reference viewed: 6 (0 ULg)
Peer Reviewed
See detailA Prenatal Trisomy 21 Screening Program Using Alpha-Fetoprotein, Human Chorionic Gonadotropin, and Free Estriol Assays on Maternal Dried Blood
Verloes, Alain ULg; Schoos, Roland ULg; Herens, Christian ULg et al

in American Journal of Obstetrics and Gynecology (1995), 172(1, Pt 1), 167-74

OBJECTIVE: The feasibility of large-scale Down syndrome maternal screening with dried blood samples and nonradioactive methods was examined. STUDY DESIGN: A prospective observation study was performed on ... [more ▼]

OBJECTIVE: The feasibility of large-scale Down syndrome maternal screening with dried blood samples and nonradioactive methods was examined. STUDY DESIGN: A prospective observation study was performed on a nonselected population of 11,241 pregnant women sampled between January 1991 and September 1992, between 14 and 24 weeks' gestation (ultrasonographic scanning available for 91.6%), through a multicenter collaborative network. Enzyme-linked immunosorbent assays for alpha-fetoprotein, human chorionic gonadotropin, and free estriol were performed on dried blood samples. Risk determination was made with an in-house software implementing the multivariate gaussian log likelihood method. RESULTS: A total of 10,450 samples were eligible for the study. Mean age at term was 27.9 years. A total of 6.84% of the patients were > or = 35 years old with a prior risk of trisomy 21 > 1:350. The general positive rate of our sample was 8.15%. After calculation 31.7% with prior risk > 1:350 were still in the high-risk group; 6.36% of the low-risk group were found to be at high risk for Down syndrome. Fifteen trisomic pregnancies were observed, of which 11 had a calculated risk higher than the selected cutoff value (1:350). The overall detection rate was 73%, specificity was 92%, and positive predictive power was 1.2%. CONCLUSION: Our pilot study has shown performances within the range of conventional serum screening programs. Dried blood assays are a handy alternative to serum assays. Blot paper cards represent a simple method of sampling, well fitted for large population screening. Combined with nonradioactive methods, this method appears to be both low cost and effective. The current work apparently is the first large-scale Down screening program performed with dried blood. [less ▲]

Detailed reference viewed: 10 (1 ULg)
See detailPrenatal undernutrition of the chicken changes the glucose metabolism in the liver at hatch and alters post-hatch performance
Willems, Els; Hu, T; Buyse, Johan et al

in Proceedings of the XXIV World's Poultry Congress (2012)

Detailed reference viewed: 7 (0 ULg)
Full Text
See detailPrenatal undernutrition of the chicken embryo affects post hatch feed intake, body weight and composition.
Willems, E.; Wang, Y.; Willemsen, H. et al

Scientific conference (2012)

Detailed reference viewed: 13 (0 ULg)
See detailPrenatal undernutrition of the chicken embryo leads to changes in plasma T3 and corticosterone levels
Willems, Els; Wang, Yufeng; Willemsen, Hilke et al

Poster (2012)

Detailed reference viewed: 7 (0 ULg)
Full Text
See detailPrendre l’avion de Charleroi à Liège ?
Ozer, Pierre ULg; Perrin, Dominique ULg

Article for general public (2006)

Dès le 1er novembre, six fois par semaine, notre région aura son vol Charleroi-Liège, soit une distance de 84 kilomètres en Boeing 737-400. Soit un record de lâcher de CO2 pour une si petite distance à l ... [more ▼]

Dès le 1er novembre, six fois par semaine, notre région aura son vol Charleroi-Liège, soit une distance de 84 kilomètres en Boeing 737-400. Soit un record de lâcher de CO2 pour une si petite distance à l'heure du Protocole de Kyoto ! [headline] Sous le titre « Excellente nouvelle pour la communauté marocaine et les amateurs de soleil », la nouvelle a été annoncée haut et fort à la mi-septembre : « Au terme de négociations fructueuses avec les directions des aéroports de Charleroi Bruxelles Sud et Liège, la compagnie aérienne Jet4you a décidé, dès le 01 novembre 2006, de lancer trois vols hebdomadaires vers Casablanca à partir de 18 Euros tous frais compris ». Vous avez bien lu. Il en coûtera moins de faire Charleroi-Casablanca en avion que de faire Charleroi-Liège en train (première classe) pour les privilégiés qui bénéficieront de ce prix d'appel. Pourquoi donc comparer Casablanca et Liège ? Simplement car l'avion reliera bien Charleroi à Liège, puis Liège à la capitale économique du Maroc. En d'autres termes, six fois par semaine, notre région aura son vol Charleroi-Liège, soit une distance de 84 kilomètres. Un record de très courte distance, sinon mondial, au moins européen… Et si cela répond directement à une forte demande d'une clientèle sans cesse croissante, on peut se demander quel est le coût environnemental de la mise en place d'une telle liaison opérée par un Boeing 737-400. [...] [less ▲]

Detailed reference viewed: 233 (37 ULg)
Peer Reviewed
See detailPrendre l'humour au sérieux: prolégomènes à une étude du discours comique
Defays, Jean-Marc ULg

Conference (1993, November)

Detailed reference viewed: 18 (1 ULg)
See detailPrendre position, entrer en théâtre
Delhalle, Nancy ULg

Scientific conference (2009, November 09)

Detailed reference viewed: 12 (3 ULg)
See detailPrendre soin de la nature ordinaire
Mougenot, Catherine ULg

Book published by INRA / Maison des sciences de l'homme (2003)

Les champs cultivés, les prairies, les bocages, les bords de route, les friches industrielles... sont de plus en plus l'objet d'actions d'intérêt biologique. Cette nature ordinaire est hybride, c'est un ... [more ▼]

Les champs cultivés, les prairies, les bocages, les bords de route, les friches industrielles... sont de plus en plus l'objet d'actions d'intérêt biologique. Cette nature ordinaire est hybride, c'est un mélange de nature sauvage et de nature domestique qui fait l'objet d'une politique de gestion négociée avec les citoyens. Le livre évoque cette question en prenant pour exemple les Plans Communaux de Développement de la Nature (PCDN) développés en Belgique [less ▲]

Detailed reference viewed: 105 (15 ULg)
Full Text
Peer Reviewed
See detailPrenons garde aux lésions kystiques cutanées. Du dérisoire au méritoire.
Hermanns-Lê, Trinh ULg; Hermanns, Jean-François ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2002), 57(5), 314-6

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be ... [more ▼]

Cutaneous cystic-like lesions do not always correspond to real epithelial cysts. Indeed, the histological examination may identify another benign tumour. But, in some instances, the surprise may be greater. We report three patients in whom lesions suggested clinically small cysts. However, they were malignant neoplasms corresponding to a malignant fibrous histiocytoma, an epithelioid angiosarcoma and a metastatic adenocarcinoma, respectively. [less ▲]

Detailed reference viewed: 26 (5 ULg)
Peer Reviewed
See detailPreoperative and long term treatment of acromegaly with SMS 201-995.
Beckers, Albert ULg; Stevenaert, Achille ULg; Hennen, G.

Conference (1987)

Detailed reference viewed: 5 (0 ULg)
See detailPreoperative assessment of the patient undergoing chest surgery
Brichant, Jean-François ULg

Conference (2003, March)

Detailed reference viewed: 1 (0 ULg)
Full Text
See detailPreoperative Brain Image Update with FEM- and XFEM-based Biomechanical Model
Vigneron, Lara; Boman, Romain ULg; Robe, Pierre et al

in 7th World Congress on Computational Mechanics (2006, July)

Detailed reference viewed: 26 (8 ULg)
Peer Reviewed
See detailPreoperative Brain Image Update with FEM- and XFEM-based Biomedical Model
Vigneron, Lara M.; Boman, Romain C.; Robe, Pierre A. et al

Conference (2006)

Detailed reference viewed: 3 (0 ULg)
See detailPreoperative evaluation in the developed countries
Brichant, Jean-François ULg

Conference (2004, April)

Detailed reference viewed: 3 (0 ULg)
Full Text
Peer Reviewed
See detailPreoperative evaluation of 54 gliomas by PET with fluorine-18-fluorodeoxyglucose and/or carbon-11-methionine.
Kaschten, Bruno ULg; Stevenaert, Achille ULg; Sadzot, Bernard ULg et al

in Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine (1998), 39(5), 778-85

This study evaluates the usefulness of PET for the preoperative evaluation of brain gliomas and methods of quantification of PET results. METHODS: Fifty-four patients with brain gliomas were studied by ... [more ▼]

This study evaluates the usefulness of PET for the preoperative evaluation of brain gliomas and methods of quantification of PET results. METHODS: Fifty-four patients with brain gliomas were studied by PET with 18F-fluorodeoxyglucose (FDG) (n = 45) and/or 11C-methionine (MET) (n = 41) before any treatment. Results of visual analysis, calculation of glucose consumption and five tumor-to-normal brain ratios for both tracers were correlated with two histologic grading systems and with follow-up. RESULTS: Visual analysis (for FDG) and tumor-to-mean cortical uptake (T/MCU) ratio proved to be the best tools for the evaluation of PET results. Methionine was proven to be better than FDG at delineating low-grade gliomas. Tumor-to-mean cortical uptake ratios for FDG and MET were clearly correlated (r = 0.78), leading to the equation T/MCU(FDG) = 0.4 x T/MCU(MET). We showed a good correlation between FDG PET and histologic grading. MET uptake could not differentiate between low-grade and anaplastic astrocytomas but was significantly increased in glioblastomas. Low-grade oligodendrogliomas exhibited high uptake of FDG and MET, probably depending more on oligodendroglial cellular differentiation than on proliferative potential. Uptake was decreased in anaplastic oligodendrogliomas, probably due to dedifferentiation. Care must be taken with peculiar histologic subgroups, i.e., juvenile pilocytic astrocytomas and oligodendrogliomas, because of a discrepancy between high PET metabolism and low proliferative potential (good prognosis). Both tracers proved useful for the prediction of survival prognosis. Methionine proved slightly superior to FDG for predicting the histologic grade and prognosis of gliomas, despite the impossibility of differentiation between Grades II and III astrocytomas with MET. This superiority of MET could be explained by patient sampling (low number of Grade III gliomas submitted to examination with both tracers). The combination of both tracers improved the overall results compared to each tracer alone. CONCLUSION: Both tracers are useful for the prediction of the histologic grade and prognosis. The apparent superiority of MET over FDG could be due to the small number of Grade III gliomas studied with both tracers. [less ▲]

Detailed reference viewed: 74 (2 ULg)
Full Text
Peer Reviewed
See detailPreoperative hyperfractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective phase II trial
Coucke, Philippe ULg; Notter; Stamm et al

in Radiotherapy & Oncology (2005)

Background and purpose We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer ... [more ▼]

Background and purpose We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer (LARC). This fractionation schedule was designed to keep the overall treatment time (OTT) as short as possible. Patients and methods This is a prospective trial on patients with UICC stages II and III rectal cancer. The patients were submitted to a total dose of 41.6 Gy, delivered in 2.5 weeks at 1.6 Gy per fraction twice a day with a 6-h interfraction interval. Surgery was performed within 1 week after the end of irradiation. Adjuvant chemotherapy was delivered in a subset of patients. Results Two hundred and seventy nine patients were entered and 250 are fully assessable, with a median follow-up of 39 months. The 5-years actuarial local control (LC) rate is 91.7%. The overall survival (OS) is 59.6%. The freedom from disease relapse (FDR) is 71.5%. Downstaging was observed in 38% of the tumors. Conclusion The actuarial LC at 5 years is 91.7%, although we are dealing with stages II–III LARC, mainly located in the lower rectum (median distance=5 cm). The pattern of failure is dominated by distant metastases and treatment intensification will obviously require a systemic approach. [less ▲]

Detailed reference viewed: 12 (1 ULg)
Full Text
Peer Reviewed
See detailPréoperative hyperfractionated accelerated radiotherapy (HART) in locally advanced rectal cancer (LARC) immediately followed by surgery. A prospective trial.
Coucke, Philippe ULg; Notter, M; Matter, M et al

in Radiotherapy & Oncology (2006), 79

Abstract Background and purpose: We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal ... [more ▼]

Abstract Background and purpose: We aim to report on local control in a phase II trial on preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer (LARC). This fractionation schedule was designed to keep the overall treatment time (OTT) as short as possible. Patients and methods: This is a prospective trial on patients with UICC stages II and III rectal cancer. The patients were submitted to a total dose of 41.6 Gy, delivered in 2.5 weeks at 1.6 Gy per fraction twice a day with a 6-h interfraction interval. Surgery was performed within 1 week after the end of irradiation. Adjuvant chemotherapy was delivered in a subset of patients. Results: Two hundred and seventy nine patients were entered and 250 are fully assessable, with a median follow-up of 39 months. The 5-years actuarial local control (LC) rate is 91.7%. The overall survival (OS) is 59.6%. The freedom from disease relapse (FDR) is 71.5%. Downstaging was observed in 38% of the tumors. Conclusion: The actuarial LC at 5 years is 91.7%, although we are dealing with stages II–III LARC, mainly located in the lower rectum (median distanceZ5 cm). The pattern of failure is dominated by distant metastases and treatment intensification will obviously require a systemic approach. q 2006 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 79 (2006) 52–58. [less ▲]

Detailed reference viewed: 41 (1 ULg)