A stress-strain framework for modelling the behaviour of unsaturated soils under non-isothermal conditions.François, Bertrand ; in Springer Proceedings in Physics 113, Theoretical and Numerical Unsaturated Soils Mechanics (2007) This paper addresses a new, unified thermo-mechanical constitutive model for unsaturated soils through a coupled study. In the context of elastoplasticity and the critical state theory, the model uses the ... [more ▼] This paper addresses a new, unified thermo-mechanical constitutive model for unsaturated soils through a coupled study. In the context of elastoplasticity and the critical state theory, the model uses the concepts of multimechanism and bounding surface theory. This advanced constitutive approach involves thermo-plasticity of saturated and unsaturated soils. Bishop’s effective stress framework is adopted to represent the stress state in the soil. This stress is linked to the water retention curve, which is represented by an elasto-plastic model. Attention is focused particularly on the coupling relations inferred from this unified thermohydro-mechanical (THM) study. Finally, the theoretical aspects of the paper are supported by comparisons between numerical simulations and experimental results. [less ▲] Detailed reference viewed: 12 (1 ULg) Stretching calorimetry studies of poly(epsilon-caprolactone)/organoclay nanocomposites; ; et al in Polymer (2005), 46(6), 1943-1948 Poly(epsilon-caprolactone)/montmorillonite nanocomposites, prepared by bulk ring-opening polymerization of epsilon-caprolactone in the presence of tin(II) 2-ethylhexanoate as a catalyst and hydroxy groups ... [more ▼] Poly(epsilon-caprolactone)/montmorillonite nanocomposites, prepared by bulk ring-opening polymerization of epsilon-caprolactone in the presence of tin(II) 2-ethylhexanoate as a catalyst and hydroxy groups of ammonium tethers of organoclay acting as chain-growth centers, were characterized by the stretching calorimetry technique. In the range of elastic (reversible) deformations, experimental Young's moduli and linear thermal expansivities of both the intercalated and exfoliated nanocomposites could be fitted to the predictions of Chow's model assuming the apparent aspect ratio of clay nanoparticles of the order of 10. In the range of anelastic deformations, the values of the internal energy increments DeltaU/m for the intercalated nanocomposite lay somewhat below those for the corresponding neat polymer, while the DeltaU/m vs. epsilon plots for the exfoliated nanocomposite and for the corresponding neat polymer were nearly identical both in shape and in absolute values over the entire range of strains, up to the breaking strains epsilon(b). These data suggested higher and lower probabilities of interfacial debonding in the range of anelastic deformations for intercalated and exfoliated samples, respectively. [less ▲] Detailed reference viewed: 33 (3 ULg) Streven naar een gezinnenrechtLeleu, Yves-Henri ![]() in Notarius : Revue pour le Notariat (2007), 3 Detailed reference viewed: 4 (1 ULg) Striae distensae in darker skin types: the influence of melanocyte mechanobiology.Pierard, Claudine ; Hermanns, Jean-François ; Hermanns-Le, Trinh et alin Journal of Cosmetic Dermatology (2005), 4(3), 174-8 Introduction Striae distensae in White people are commonly described as being reddish at first and turning white in time. This dual perception has been challenged. Indeed, the color difference between ... [more ▼] Introduction Striae distensae in White people are commonly described as being reddish at first and turning white in time. This dual perception has been challenged. Indeed, the color difference between striae distensae and their surrounding skin varies on a wide range in part depending upon typology. Aim To study striae nigrae that are found only in subjects of darker complexion. Materials and methods In the present study conducted in 44 darker skin adults, dermoscopy was combined to reflectance colorimetry. Results Striae nigrae exhibited hypermelanosis of the epidermal rete ridges crossing transversally the lesions in a laddering pattern. By contrast, striae albae showed only faint melanotic networks. Conclusions As striae distensae are in part under the influence of skin stretching, their colors are likely to be controlled by some mechanobiological process activating or inhibiting melanogenesis in people of darker complexion. No argument involving an inflammatory mechanism is supported by the present observations. [less ▲] Detailed reference viewed: 31 (1 ULg) Striatal Contribution to sleep-dependent motor consolidation; ; et al in NeuroImage (2008), 41(Suppl. 1), Detailed reference viewed: 9 (1 ULg) Striatal PSA-NCAM(+) precursor cells from the newborn rat express functional glycine receptorsNguyen, Laurent ; Malgrange, Brigitte ; Breuskin, Ingrid et alin Neuroreport (2004), 15(4), 583-587 Immunocytochemical analysis showed that ionotropic glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum and expressing the polysialylated form of the neural ... [more ▼] Immunocytochemical analysis showed that ionotropic glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum and expressing the polysialylated form of the neural cell adhesion molecule, both in vitro and in situ. To ascertain whether glycine receptors were functional in vitro, whole-cell patch-clamp recordings demonstrated that glycine triggers inward strychnine-sensitive currents in the majority of these cells. Moreover, we found that glycine receptors expressed by these neurogenic progenitors display intermediate electrophysiological characteristics between those of glycine receptors expressed by neural stem cells and by mature interneurons from the rat striatum. Altogether, the present data show that functional strychnine-sensitive glycine receptors are expressed in neurogenic progenitors purified from the newborn rat striatum. [less ▲] Detailed reference viewed: 16 (4 ULg) Striatum forever, despite sequence learning variability : A random effect analysis of PET dataPeigneux, Philippe ; Maquet, Pierre ; Meulemans, Thierry et alin Human Brain Mapping (2000), 10(4), 179-194 This PET study is concerned with the what, where, and how of implicit sequence learning. In contrast with previous studies imaging the serial reaction time (SRT) task, the sequence of successive locations ... [more ▼] This PET study is concerned with the what, where, and how of implicit sequence learning. In contrast with previous studies imaging the serial reaction time (SRT) task, the sequence of successive locations was determined by a probabilistic finite-state grammar. The implicit acquisition of statistical relationships between serially ordered elements (i.e., what) was studied scan by scan, aiming to evidence the brain areas (i.e., where) specifically involved in the implicit processing of this core component of sequential higher-order knowledge. As behavioural results demonstrate between- and within-subjects variability in the implicit acquisition of sequential knowledge through practice, functional PET data were modelled using a random-effect model analysis (i.e., how) to account for both sources of behavioural variability. First, two mean condition images were created per subject depending on the presence or not of implicit sequential knowledge at the time of each of the 12 scans. Next, direct comparison of these mean condition images provided the brain areas involved in sequential knowledge processing. Using this approach, we have shown that the striatum is involved in more than simple pairwise associations and that it has the capacity to process higher-order knowledge. We suggest that the striatum is not only involved in the implicit automatization of serial information through prefrontal cortex-caudate nucleus networks, but also that it plays a significant role for the selection of the most appropriate responses in the context created by both the current and previous stimuli, thus contributing to better efficiency and faster response preparation in the SRT task. Hum. Brain Mapping 10:179-194, 2000. © 2000 Wiley-Liss, Inc. [less ▲] Detailed reference viewed: 2 (0 ULg) Strictureplasty in Crohn's disease : Short- and long-term follow-up; Detry, Olivier ; Detroz, Bernard et alin Acta Chirurgica Belgica (2002), 102(4, JUL-AUG), 253-255 Strictureplasty for obstructive Crohn's disease is still controversial because lesions are left in place and the suture is performed on a diseased bowel. Many surgeons prefer to perform bowel resection ... [more ▼] Strictureplasty for obstructive Crohn's disease is still controversial because lesions are left in place and the suture is performed on a diseased bowel. Many surgeons prefer to perform bowel resection, hoping for fewer complications and a lower recurrence rate. In this paper, the authors reports their strictureplasty experience. They performed a systematic retrospective review of the patients suffering from Crohn's disease who underwent strictureplasties during a 10-year period in the abdominal surgery department of the University Hospital of Liege Sart Tilman, and studied the short- and long-term clinical results of 68 strictureplasties performed in 18 patients. Median follow-up was 63 months (range 12 to 144). Mortality was 0% and septic morbidity was 11% (one wound abscess and one leakage). Among the 16 patients available for the latest follow-up, symptomatic stenotic recurrence had to be medically treated in hospital for 4 patients (25%) with a recurrence delay range of 19 to 49 months. Stenosis recurrence needed re-intervention in one patient 48 months after surgery: stenosis occurred at a distance from the corrected site. These results confirmed that strictureplasty is a safe and efficient procedure in selected patients undergoing surgery for obstructive Crohn's disease. [less ▲] Detailed reference viewed: 44 (4 ULg) Stricturoplasty in Crohn disease: short and long term follow up; Detry, Olivier ; Detroz, Bernard et alin Acta Gastro-Enterologica Belgica (2001, January), 64(1), 73 Detailed reference viewed: 26 (1 ULg) De strijd tegen (schijn)huwelijken voltrokken in het buitenland : is het Belgisch ipr aan een update toe?Wautelet, Patrick ![]() in Erauw, Johan (Ed.) Nieuw Internationaal Privaatrecht - meer europees, meer globaal (2009) In this paper, I argue that the current legal framework as it stands offers sufficient means to refuse any effect to a marriage celebrated outside Belgium if it appears that it is a marriage of ... [more ▼] In this paper, I argue that the current legal framework as it stands offers sufficient means to refuse any effect to a marriage celebrated outside Belgium if it appears that it is a marriage of convenience. There has been much talk of strenghtening and fine tuning the legal framework in order to offer real protection against such foreign sham marriages. A thorough analysis of the law as it stands, and in particular of Article 27 of the Code of Privat International Law reveals that such fine tuning is by no means necessary. Article 27 properly applied already offers sufficient protection against such marriages. The analysis also reveals that in order to refuse effect to foreign marriages of convenience, it is not even necessary to call upon the doctrine of ordre public or of fraus legem, to which Article 27 refers. The application of these two doctrines appears to be very complex and will in most cases not be necessary. [less ▲] Detailed reference viewed: 55 (3 ULg) The stringent response mediator Rsh is required for Brucella melitensis and Brucella suis virulence, and for expression of the type IV secretion system virB.; ; et al in Cellular Microbiology (2006), 8(11), 1791-802 Physiological adaptation of intracellular bacteria is critical for timely interaction with eukaryotic host cells. One mechanism of adaptation, the stringent response, is induced by nutrient stress via its ... [more ▼] Physiological adaptation of intracellular bacteria is critical for timely interaction with eukaryotic host cells. One mechanism of adaptation, the stringent response, is induced by nutrient stress via its effector molecule (p)ppGpp, synthesized by the action of RelA/SpoT homologues. The intracellular pathogen Brucella spp., causative agent of brucellosis, possesses a gene homologous to relA/spoT, named rsh, encoding a (p)ppGpp synthetase as confirmed by heterologous complementation of a relA mutant of Sinorhizobium meliloti. The Rsh deletion mutants in Brucella suis and Brucella melitensis were characterized by altered morphology, and by reduced survival under starvation conditions and in cellular and murine models of infection. Most interestingly, we evidenced that expression of virB, encoding the type IV secretion system, a major virulence factor of Brucella, was Rsh-dependent. All mutant phenotypes, including lack of VirB proteins, were complemented with the rsh gene of Brucella. In addition, RelA of S. meliloti functionally replaced Brucella Rsh, describing the capacity of a gene from a plant symbiont to restore virulence in a mammalian pathogen. We therefore concluded that in the intramacrophagic environment encountered by Brucella, Rsh might participate in the adaptation of the pathogen to low-nutrient environments, and indirectly in the VirB-mediated formation of the final replicative niche. [less ▲] Detailed reference viewed: 8 (2 ULg) Stripe patterns in self-stratification experiments; Vandewalle, Nicolas ![]() in Fractals-Complex Geometry Patterns and Scaling in Nature and Society (2003), 11(Suppl. S), 259-269 We report pattern formation of complex stripes with binary and ternary granular mixtures. Ternary mixtures lead to a particular ordering of the strates which was not accounted for in former explanations ... [more ▼] We report pattern formation of complex stripes with binary and ternary granular mixtures. Ternary mixtures lead to a particular ordering of the strates which was not accounted for in former explanations. Bouncing grains are found to have an important effect on strate formation. A complementary mechanism for self-stratification of binary and ternary granular mixtures is proposed. This mechanism leads to a simple model. Eventually we report the observation of self-stratification for a binary mixture of grains of the same size but with different shapes. [less ▲] Detailed reference viewed: 2 (0 ULg) Stripes Ordering in Self-Stratification Experiments of Binary and Ternary Granular Mixtures; Vandewalle, Nicolas ![]() in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (2000), 62(6, Pt B), 8241-4 The self-stratification of binary and ternary granular mixtures has been experimentally investigated. Ternary mixtures lead to a particular ordering of the strata which was not accounted for in former ... [more ▼] The self-stratification of binary and ternary granular mixtures has been experimentally investigated. Ternary mixtures lead to a particular ordering of the strata which was not accounted for in former explanations. Bouncing grains are found to have an important effect on stratum formation. A complementary mechanism for self-stratification of binary and ternary granular mixtures is proposed. [less ▲] Detailed reference viewed: 4 (1 ULg) Stripkritiek in Vlaanderen; Meesters, Gert ![]() in Kreatief (2002), 36(2), 4-15 Detailed reference viewed: 24 (0 ULg) Strips in de taalklas. Zes lesvoorbereidingen voor het middelbaar onderwijs.Meesters, Gert ; Learning material (2010) Lesvoorbereidingen bij de volgende strips: De maagd en de neger (J. Vanistendael), Ghost World (D. Clowes), Persepolis (M. Satrapi), Over naar jou (P. Paquet & A. Van Aken), Weer over naar jou (P. Paquet ... [more ▼] Lesvoorbereidingen bij de volgende strips: De maagd en de neger (J. Vanistendael), Ghost World (D. Clowes), Persepolis (M. Satrapi), Over naar jou (P. Paquet & A. Van Aken), Weer over naar jou (P. Paquet & A. Van Aken). [less ▲] Detailed reference viewed: 100 (6 ULg) Strips in het Nederlands. Onbekend is ongebruikt.Meesters, Gert ![]() in Fenoulhet, Jane; Gelderblom, Arie G.; Kristel, Marja (Eds.) et al Neerlandistiek in contrast. Bijdragen aan het Zestiende Colloquium Neerlandicum (2007) Ondanks al de aandacht die de laatste jaren uitgaat naar culturele studies en vergelijkende letterkunde en ondanks de daarmee samenhangende opwaardering van de zogenaamde populaire cultuur als onderwerp ... [more ▼] Ondanks al de aandacht die de laatste jaren uitgaat naar culturele studies en vergelijkende letterkunde en ondanks de daarmee samenhangende opwaardering van de zogenaamde populaire cultuur als onderwerp voor wetenschappelijk onderzoek, blijft het Nederlandstalige stripverhaal voor de meeste mensen onbekend terrein. Zelfs moedertaalsprekers van het Nederlands kunnen vaak slechts enkele Nederlandstalige strips noemen. Met deze bijdrage wil ik ten eerste een uitgebreide introductie presenteren tot de bijzonder gevarieerde stripcultuur uit Vlaanderen en Nederland. Daarbij komen geschiedenis, geografische diversiteit, doelgroepvariatie, maatschappelijke positie, internationale uitstraling en actuele tendensen ter sprake. Die thema's worden telkens geïllustreerd met voorbeeldstrips, zodat de toehoorder ook terloops kennis maakt met het concrete werk. Ten tweede geef ik een idee van de praktische toepassingen die strips zouden kunnen hebben in het onderwijs van het Nederlands als vreemde taal. In literatuurcolleges, in taalbeheersingscolleges of in colleges geschiedenis en Landeskunde, kortom in vele types colleges kunnen strips uit Nederland en Vlaanderen een didactische meerwaarde bieden. [less ▲] Detailed reference viewed: 29 (1 ULg) Striptease em raio-x: algumas interrelações artístico-científicas no domínio visual.Sturnack, Lionel ![]() Conference (2012, March 28) O striptease que propomos analisar é na verdade o título de uma obra que pertence à produção da artista italiana Benedetta Bonichi. Trata-se de uma composição mista, a meio caminho entre os raios-x e a ... [more ▼] O striptease que propomos analisar é na verdade o título de uma obra que pertence à produção da artista italiana Benedetta Bonichi. Trata-se de uma composição mista, a meio caminho entre os raios-x e a fotografia. “Striptease” constitui uma base analítica interessante para várias razões. Com certeza, por seu caráter surpreendente, sendo uma cena erótica e ao mesmo tempo uma radiografia. Mas também e sobretudo por sua estética particular em relação aos outros artistas que desenvolvem uma técnica similar. Uma parte do nosso estudo consistirá na abordagem indispensável mesmo que breve das realizações de quatro outros artistas que trabalham com os raios-x. O propósito de nossos passos é levar em consideração o lugar da obra estudada no espaço de realizações em raio-x artístico, numa perspectiva semiótica. Pretendemos desta maneira chegar à descrição fina de “Striptease”, ou seja, conseguir por um lado estabelecer os critérios sobre os quais se correlacionam e se diferenciam os raios-x artísticos vistos e, por outro lado e graças à primeira etapa, dar conta da riqueza da obra da italiana. Desenvolveremos o estudo segundo três etapas gerais. Com a primeira, efetuaremos uma descrição de “Striptease” segundo os três eixos da leitura plástica padrão, tal como foram trabalhados por Jean-Marie Floch: cromático, eidético e topológico. Na segunda etapa, adotaremos o mesmo ponto de vista para a descrição plástica de cinco obras de quatro outros artistas: Nick Veasey, a agência Butter, Wim Delvoye e Claudio Mubarac. O interesse da segunda parte consiste em mostrar que o tipo de descrição estabelecido para “Striptease” vale nos outros casos e como se atualizam as unidades plásticas em cada realização particular, a fim de observar as suas possíveis convergências. Na última etapa, poderemos considerar a estética de cada obra à luz das atualizações plásticas e das integrações entre elas com outros patamares temáticos. Conseguiremos, finalmente, entender a pertinência e a particularidade de “Striptease” como metalinguagem crítica por meio destas considerações temáticas e plásticas. [less ▲] Detailed reference viewed: 19 (2 ULg) Stroboscopic real-time holographic interferometry with photorefractive crystals applied to modal analysisGeorges, Marc ; Lemaire, Philippe ![]() in Gorecki, Christophe (Ed.) Optical Inspection and Micromeasurements II (1997, June) A breadboard holographic interferometer that uses a photorefractive sillenite crystal under the anisotropic diffraction configuration is presented for application to quantitative vibration measurements ... [more ▼] A breadboard holographic interferometer that uses a photorefractive sillenite crystal under the anisotropic diffraction configuration is presented for application to quantitative vibration measurements. After the hologram of the object at the rest is recorded, a stroboscope is used to observe the stable pattern of the vibrating object and phase-shifting is introduced for quantitative measurements. It is shown that this system can measure modal displacements of objects of typically 25*25 cm/sup 2/ with high accuracy ( lambda /40) by using a continuous YAG laser emitting 490 mW at 532 nm. The error sources are investigated and particularly a systematic error arising from the stroboscopic process can be calculated and eliminated [less ▲] Detailed reference viewed: 4 (0 ULg) Stromal Estrogen Receptor-α Promotes Tumor Growth by Normalizing an Increased Angiogenesis.Pequeux, Christel ; ; Blacher, Silvia et alin Cancer Research (2012), 72(12), 3010-3019 Estrogens directly promote the growth of breast cancers that express the Estrogen Receptor (ERalpha). However, the contribution of stromal expression of ERalpha in the tumor microenvironment to the pro ... [more ▼] Estrogens directly promote the growth of breast cancers that express the Estrogen Receptor (ERalpha). However, the contribution of stromal expression of ERalpha in the tumor microenvironment to the pro-tumoral effects of estrogen has never been explored. In this study, we evaluated the molecular and cellular mechanisms by which 17beta-estradiol (E2) impacts the microenvironment and modulates tumor development of ERalpha-negative tumors. Using different mouse models of ER-negative cancer cells grafted subcutaneously into syngeneic ovariectomized immunocompetent mice, we found that E2 potentiates tumor growth, increases intratumoral vessel density and modifies tumor vasculature into a more regularly organized structure, thereby improving vessel stabilization to prevent tumor hypoxia and necrosis. These E2-induced effects were completely abrogated in ERalpha-deficient mice, demonstrating a critical role of host ERα. Notably, E2 did not accelerate tumor growth when ERalpha was deficient in Tie2- positive cells, but still expressed by bone marrow derived cells. These results were extended by clinical evidence of ERalpha-positive stromal cell labeling in the microenvironment of human breast cancers. Together, our findings therefore suggest that E2 promotes the growth of ERalpha-negative cancer cells through the activation of stromal ERα (not hematopoiteic but Tie2-dependent expression of ERalpha), which normalizes tumor angiogenesis and allows an adaptation of blood supply to tumor demand preventing hypoxia and necrosis. These findings significantly deepen mechanistic insights into the impact of E2 on tumor development with potential consequences for cancer treatment. [less ▲] Detailed reference viewed: 25 (6 ULg) Stromal regulation of vessel stability by MMP14 and TGFbeta.Sounni, Nor Eddine ; ; et alin Disease Models & Mechanisms (2010), 3 Innate regulatory networks within organs maintain tissue homeostasis and facilitate rapid responses to damage. We identified a novel pathway regulating vessel stability in tissues involving matrix ... [more ▼] Innate regulatory networks within organs maintain tissue homeostasis and facilitate rapid responses to damage. We identified a novel pathway regulating vessel stability in tissues involving matrix metalloproteinase 14 (MMP14) and transforming growth factor beta (TGFbeta)1. Whereas plasma proteins rapidly extravasate out of vasculature in wildtype mice following acute damage, short-term treatment of mice in vivo with a broad-spectrum metalloproteinase inhibitor, neutralizing antibodies to TGFbeta1 or an ALK5 inhibitor significantly enhanced vessel leakage. In contrast, in a mouse model of age-related dermal fibrosis where MMP14 activity and TGFbeta bioavailability are chronically elevated, or in mice that ectopically express TGFbeta in epidermis, cutaneous vessels are resistant to acute leakage. Characteristic responses to tissue damage are reinstated if fibrotic mice are pre-treated with metalloproteinase inhibitors or TGFbeta signaling antagonists. Neoplastic tissues on the other hand are in a constant state of tissue damage and exhibit altered hemodynamics due to hyperleaky angiogenic vasculature. In two distinct transgenic mouse tumor models, inhibition of ALK5 further enhanced vascular leakage into interstitium and facilitated increased delivery of high molecular weight compounds into premalignant tissue and tumors. Taken together, these data define a central pathway involving MMP14 and TGFbeta that mediate vessel stability and vascular response to tissue injury. Antagonists of this pathway could be therapeutically exploited to improve delivery of therapeutics or molecular contrast agents into tissues where chronic damage or neoplastic disease limits their efficient delivery. [less ▲] Detailed reference viewed: 162 (8 ULg) |
||