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See detailPrediction of the acoustics of coupled rooms with the acoustic-diffusion model
Valeau, Vincent; Billon, Alexis ULg; Hodgson, Murray et al

Conference (2006, June)

A general model is proposed to simulate the acoustics of coupled rooms. It is based on a diffusion equation, solved numerically to perform acoustic predictions. The presence of scattering objects –or the ... [more ▼]

A general model is proposed to simulate the acoustics of coupled rooms. It is based on a diffusion equation, solved numerically to perform acoustic predictions. The presence of scattering objects –or the “fittings”– is also taken into account. Distinct sub-volumes can be defined, representing either coupled volumes or zones with different fitting characteristics. Some sample results are presented, and compared with ray-tracing results and experimental data. Two situations are assessed: two coupled classrooms, and a room divided into two zones, one empty, one fitted. The diffusion-model predictions match the other data satisfactorily, both in terms of sound attenuation and sound decay. Diffusion-based results are obtained with the advantage of low computational time compared to ray-tracing results. [less ▲]

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See detailPrediction Of The Antigenic Sites Of The Cystic-Fibrosis Transmembrane Conductance Regulator Protein By Molecular Modeling
Gallet, X.; Benhabiles, N.; Lewin, M. et al

in Protein Engineering (1995), 8(8), 829-34

Antibodies are powerful tools for studying the in situ localization and physiology of proteins. The prediction of epitopes by molecular modelling has been used successfully for the papilloma virus, and ... [more ▼]

Antibodies are powerful tools for studying the in situ localization and physiology of proteins. The prediction of epitopes by molecular modelling has been used successfully for the papilloma virus, and valuable antibodies have been raised [Muller et al. (1990) J. Gen. Virol., 71, 2709-2717]. We have improved the modelling approach to allow us to predict epitopes from the primary sequences of the cystic fibrosis transmembrane conductance regulator. The procedure involves searching for fragments of primary sequences likely to make amphipathic secondary structures, which are hydrophilic enough to be at the surface of the folded protein and thus accessible to antibodies. Amphipathic helices were predicted using the methods of Berzofsky, Eisenberg and Jahnig. Their hydrophobic-hydrophilic interface was calculated and drawn, and used to predict the orientation of the helices at the surface of the native protein. Amino acids involved in turns were selected using the algorithm of Eisenberg. Tertiary structures were calculated using 'FOLDING', a software developed by R. Brasseur for the prediction of small protein structures [Brasseur (1995) J. Mol. Graphics, in press]. We selected sequences that folded as turns with at least five protruding polar residues. One important property of antibodies is selectivity. To optimize the selectivity of the raised antibodies, each sequence was screened for similarity (FASTA) to the protein sequence from several databanks. Ubiquitous sequences were discarded. This approach led to the identification of 13 potential epitopes in the cystic fibrosis transmembrane conductance regulator: seven helices and six loops. [less ▲]

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See detailPrediction of the cross-section capacity of hot-rolled profiles using the direct strength method and the continuous strength method
Li, Yongzhen ULg; Rossi, Barbara ULg

in Chan, S.L.; Shu, G.P. (Eds.) Proceedings of seventh International Conference on Advances in Steel Structures (2012, April)

Material yielding on one hand and local buckling on the other hand limit the cross-section capacity of steel structural members. Current structural design codes use the concept of cross-section ... [more ▼]

Material yielding on one hand and local buckling on the other hand limit the cross-section capacity of steel structural members. Current structural design codes use the concept of cross-section classification to determine the cross-section resistance of hot-rolled profiles. In this system, the Effective Width Method (EWM) is employed to account for local buckling effects for slender, class 4, cross-sections. Alternative design methods for treatment of local buckling in metallic cross-sections have been proposed, including the Direct Strength Method (DSM), developed for cold-formed steel structural profiles, and, recently, the Continuous Strength Method (CSM). The DSM is based on the assumption that the strength can be predicted from the ratio of the yield strength to the elastic critical load in conjunction with a strength curve for the entire cross-section. Thus it is essentially an extension of the use of column curves for global buckling, but with application to local buckling instability. The CSM is a deformation-based design approach which is based on a continuous relationship between cross-sectional slenderness and cross-section deformation capacity and a rational exploitation of strain hardening. This paper is focused on the evaluation of the cross-sectional resistance of hot-rolled structural profiles. Test data from literature experimental programmes have been gathered and analysed to compare the predictions from the DSM and CSM design approaches. [less ▲]

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See detailPrediction of the morphological and mechanical properties of a novel scaffold ACL tissue engineering
Laurent, Cédric ULg

in Computer Methods in Biomechanics & Biomedical Engineering (2011)

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See detailPrediction of the reverberation time in rooms with non uniform absorptions using a diffusion model
Billon, Alexis ULg; Sakout, Anas

Conference (2006, July)

The acoustical comfort is now a comfort’s criterion which is taken into from the conception. The designers need therefore accurate tools to predict the acoustic quality of enclosures. Most of the ... [more ▼]

The acoustical comfort is now a comfort’s criterion which is taken into from the conception. The designers need therefore accurate tools to predict the acoustic quality of enclosures. Most of the acoustical comfort criteria are based on the reverberation time. When the room has proportionate dimensions and an uniform absorption, the statistical theory through Sabine or Eyring formulas allows good predictions of the reverberation time. Moreover, extensions of these relations by Millington or Cremer and Müller among others give quite satisfactory when the room is composed of materials with different sound absorption. In this study, the reverberation time in an enclosure is calculated via the numerical resolution of unstationary diffusion equation, model validated in coupled and industrial rooms. Firstly, an improvement of the boundary condition is proposed for highly absorbent surfaces. The diffusion model is then compared to several formulations of the statistical theory and a ray-tracing software for a cubic room with homogeneous walls’ absorption and with non homogeneous walls’ absorptions. Finally, an experimental validation is conducted for an enclosure with non uniformly distributed absorption. [less ▲]

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See detailPrediction of the Semi-Rigid and Partial-Strength Properties of Structural Joints
Jaspart, Jean-Pierre ULg; Maquoi, René ULg

in Proceedings of the SSRC Annual technical Session and Meeting (1994, June)

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See detailPrediction of the sound pressure levels using a diffusion model: numerical validations and experimental comparisons
Billon, Alexis ULg; Picaut, Judicaël

in Journal of the Acoustical Society of America (2008), 123(5), 3924-3924

redictions of sound propagation in urban areas have attracted a considerable over the years. If the sound energy is assimilated to particles with a constant energy, their movement can be described by a ... [more ▼]

redictions of sound propagation in urban areas have attracted a considerable over the years. If the sound energy is assimilated to particles with a constant energy, their movement can be described by a transport equation. In canyon streets, this transport equation can be reduced to a diffusion equation whose expression is more simple. In this presentation, sound absorption at the boundaries (buildings facades and ground), as well as atmospheric sound attenuation are introduced. The problem is then solved numerically using a finite elements method for the configuration of a canyon street. A systematic validation of the obtained model is carried out in terms of sound pressure level by comparison to numerical simulations taken from the literature. Comparisons with experimental data are then conducted. Finally, applications in more complex configurations are presented. [less ▲]

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See detailPrediction of the Tension/Compression asymmetry of ECAP processed FCC material using an integrated model based on dislocation and back-stress
Chen, Enze; Duchene, Laurent ULg; Habraken, Anne ULg et al

in Materials Science Forum (2011), 667-669

In our recent work, a new integrated model was proposed to describe the back-stress evolution based on the dislocation substructure and texture. By relating the back-stress to the dislocation density in ... [more ▼]

In our recent work, a new integrated model was proposed to describe the back-stress evolution based on the dislocation substructure and texture. By relating the back-stress to the dislocation density in cell walls and in the cell interior, this model is able to capture the back-stress evolution of ECAP processed pure aluminium. In this paper, the model is used for another FCC material, namely copper. The aim is to check whether this model is able to predict the tension/compression asymmetry (due to the back-stress) of copper. The results show that this is indeed the case and it is also found that the strain rate ratio proposed in our previous work [1] is a function of the dislocation density ratio. [less ▲]

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See detailPrédiction structurée multitâche itérative de propriétés structurelles de protéines
Maes, Francis ULg; Becker, Julien ULg; Wehenkel, Louis ULg

in 7e Plateforme AFIA: Association Française pour l'Intelligence Artificielle (2011)

Le développement d'outils informatiques pour prédire de l'information structurelle de protéines à partir de la séquence en acides aminés constitue un des défis majeurs de la bioinformatique. Les problèmes ... [more ▼]

Le développement d'outils informatiques pour prédire de l'information structurelle de protéines à partir de la séquence en acides aminés constitue un des défis majeurs de la bioinformatique. Les problèmes tels que la prédiction de la structure secondaire, de l'accessibilité au solvant, ou encore la prédiction des régions désordonnées, peuvent être exprimés comme des problèmes de prédiction avec sorties structurées et sont traditionnellement résolus individuellement par des méthodes d'apprentissage automatique existantes. Etant donné que ces problèmes sont fortement liés les uns aux autres, nous proposons de les traiter ensemble par une approche d'apprentissage multitâche. A cette fin, nous introduisons un nouveau cadre d'apprentissage générique pour la prédiction structurée multitâche. Nous appliquons cette stratégie pour résoudre un ensemble de cinq tâches de prédiction de propriétés structurelles des protéines. Nos résultats expérimentaux sur deux jeux de données montrent que la stratégie proposée est significativement meilleure que les approches traitant individuellement les tâches. [less ▲]

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See detailPredictions in overdispersed series of counts using an approximate predictive likelihood
Lambert, Philippe ULg

in Journal of Forecasting (1997), 16

The generalized autoregression model or GARM, originally used to model series of non-negative data measured at irregularly spaced time points (Lambert, 1996a), is considered in a count data context. It is ... [more ▼]

The generalized autoregression model or GARM, originally used to model series of non-negative data measured at irregularly spaced time points (Lambert, 1996a), is considered in a count data context. It is first shown how the GARM can be expressed as a GLM in the special case of a linear model for some transform of the location parameter. The Butler approximate predictive likelihood (Butler, 1986, Rejoinder) is then used to define likelihood prediction envelopes. The width of these intervals is shown to be slightly wider than the Fisher (1959, pp. 128-33) and Lejeune and Faulkenberry (1982) predictive likelihood-based envelopes which assume that the parameters have fixed known values (equal to their maximum likelihood estimates). The method is illustrated on a small count data set showing overdispersion. [less ▲]

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See detailPredictions of the reverberation time in high absorbent room using a modified-diffusion model
Billon, Alexis ULg; Picaut, Judicaël; Sakout, Anas

in Applied Acoustics (2008), 69(1), 68-74

A modification of the diffusion model’s boundary condition, based on the Eyring absorption coefficient, to account for high walls absorption is proposed. Numerical comparisons are carried out for three ... [more ▼]

A modification of the diffusion model’s boundary condition, based on the Eyring absorption coefficient, to account for high walls absorption is proposed. Numerical comparisons are carried out for three geometrical configurations (a proportionate room, a corridor and a flat enclosure). Comparisons with the statistical theory and a ray-tracing software show that the modified boundary condition increases the accuracy of the diffusion model in term of reverberation time in all the simulated configurations. An experimental comparison in the case of a non-uniformly absorbent room (a reverberation chamber covered with patches of glass wool) is also carried out. The modified-diffusion model results match well with the ray-tracing ones. Both models are in agreement with the experimental data for most of third octave bands (discrepancy close to or below 10%). However, some discrepancies up to 40% can also be observed in a few octave bands, probably due to experimental considerations and to the modal behaviour of the room at low frequencies. [less ▲]

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See detailA predictive battery of literacy acquisition for children in third year kindergarten
Gillet, Sophie ULg; Binamé, Florence ULg; Martinetti, Julie et al

Poster (2014)

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See detailPredictive Design of Honeycomb Sandwich Panels
Assaker, Roger; Depouhon, Alexandre ULg; Botman, Jean-Pierre

in Proceedings of Sampe Benelux professional meetings (2008, November)

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See detailPredictive factors for low back pain and associated sick leave in a cohort of young workers
VAN NIEUWENHUYSE, An; SOMVILLE, Pierre-René; MOENS, G. et al

(2006, June 11)

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See detailPredictive factors for response of anemia to recombinant human erythropoietin
Beguin, Yves ULg

in Nowrousian, M. R. (Ed.) Recombinant human erythropoietin (rhEPO) in clinical oncology (2002)

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See detailPredictive factors in locally advanced rectal cancer treated with preoperative hyperfractionated and accelerated radiotherapy.
Bouzourene, H; Bosman, F; Matter, M et al

in Human Pathology (2003), 34(6), 541-548

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 ... [more ▼]

This study examines the prognostic significance of pathologic factors in patients with primary locally advanced rectal cancer treated prospectively with preoperative radiotherapy. From 1992 to 1998, 104 patients with rectal cancer of grades T3 or T4 and any N underwent preoperative radiotherapy followed by surgical resection. Survival curves were estimated according to the Kaplan-Meier method. Correlation of outcome with clinicopathologic variables (pathologic tumor and lymph node staging, histology, radial resection margin [RRM], clearance, vessel involvement, and tumor regression grade [TRG], quantitated in 5 grades) was evaluated using the Cox proportional hazards model. None of the patients achieved a histologically confirmed complete pathologic response, but 79% of the patients showed partial tumor regression (TRG2–4) and 21% did not show any tumor regression (TRG5). Among the tumors, 22% were of a mucinous type. The RRM was free of tumor in 76% of the surgical specimens. The median clearance was 2 mm. Vascular invasion was present in 37 cases (36%). In the univariate analysis, lymph node metastases, absence of tumor regression, positive RRM, and vascular invasion were correlated with adverse overall survival and diseasefree survival; absence of tumor regression, positive RRM, and clearance <2 mm were correlated with local recurrences; and advanced pT stage was correlated only with disease-free survival. However, in the multivariate analysis, only lymph node metastases and RRM were independent prognostic factors for overall survival and disease-free survival, and clearance <2 mm was an independent prognostic factor for local control. Pathologic parameters remain strong determinants of local recurrence and survival in locally advanced rectal cancer, treated preoperatively with hyperfractionated and accelerated radiotherapy. We show that patients with advanced pT, positive lymph nodes, vascular invasion, positive RRM, clearance <2 mm, or absence of tumor regression are known to have poor clinical outcome. HUM PATHOL 34:541-548. © 2003 Elsevier Inc. All rights reserved. Abbreviations: , computed tomography; DFS, disease-free survival; HART, hyperfractionated accelerated radiotherapy; OS, overall survival; RRM, radial resection margin; TRG, tumor regression grade. [less ▲]

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