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See detailNetBenchmark: a bioconductor package for reproducible benchmarks of gene regulatory network inference
Bellot, Pau; Olsen, Catharina; Salembier, Philippe et al

in BMC Bioinformatics (2015)

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See detailNetherton’s syndrome in two sisters. A ten year experience of therapy with retinoids
Groves, S.; Dezfoulian, Bita ULg; Bonardeaux, Ch et al

in Journal of the European Academy of Dermatology & Venereology (1995)

Netherton’s syndrome is a recessive autosomal disease associating ichthyosiform dermatosis, hair dysplasia and systemic involvement. (Netherton, 1958, Arch. Dermatol., Vol. 78,483-487). We report the ... [more ▼]

Netherton’s syndrome is a recessive autosomal disease associating ichthyosiform dermatosis, hair dysplasia and systemic involvement. (Netherton, 1958, Arch. Dermatol., Vol. 78,483-487). We report the observation of two sisters who present the complete form of Netherton’s syndrome. Both patients were treated with retinoids for more than ten years. [less ▲]

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See detailThe NETLANDER Ionosphere and Geodesy Experiment
Barriot, Jean-Pierre; Dehant, Véronique; Folkner, W. et al

in Advances in Space Research (2001), 28(8), 1237-1249

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See detailThe Netlander Ionosphere and Geodesy Experiment
Barriot, Jean-Pierre; Dehant, Véronique; Folkner, W. et al

Conference (2001)

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See detailNetlander Ionospheric TEC Experiment
Cerisier, Jean-Claude; Axford, W. I.; Paëtzold, M. et al

Conference (1998)

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See detailNetrin-1 Mediates Early Events in Pancreatic Adenocarcinoma Progression, Acting on Tumor and Endothelial Cells.
Dumartin, L.; Quemener, C.; Laklai, H. et al

in Gastroenterology (2010), 138(4), 1595-606

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. It is characterized by substantial tumor cell invasion and early-stage metastasis. We developed an in vivo ... [more ▼]

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. It is characterized by substantial tumor cell invasion and early-stage metastasis. We developed an in vivo model to analyze interactions between cancer and stromal cells during early stages of PDAC. METHODS: Human pancreatic adenocarcinoma cells were grafted onto the chick chorioallantoic membrane (CAM). Human and chicken GeneChips were used simultaneously to study gene regulation during PDAC cell invasion. Bioinformatic analysis was used to identify human orthologs and cell specificity of gene expression. The effects of netrin-1 encoded by NTN1 were investigated in adhesion, invasion, and apoptosis assays. The effects of NTN1 silencing with small interfering RNAs were investigated in PDAC cells in vivo. NTN1 expression was measured in human PDAC samples. RESULTS: PDAC cells rapidly invade the CAM stroma and remodel the CAM vasculature. More than 870 stromal genes were up-regulated by >2-fold; the angiogenesis regulators vascular endothelial growth factor D, thrombospondin 1, and CD151 were among the most highly regulated genes. Silencing of tumor cell NTN1, which is up-regulated 4-fold in the PDAC model, inhibited tumor cell invasion in vivo. Netrin-1 conferred apoptosis resistance to tumor and endothelial cells in vitro, induced their invasion, and provided an adhesive substrate for tumor cells. NTN1 and its gene product are strongly overexpressed in human PDAC samples. CONCLUSIONS: We developed a useful tool to study the invasive mechanisms of early-stage PDAC. Netrin-1 might be an important regulator of pancreatic tumor growth that functions in tumor and endothelial cells. [less ▲]

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See detailNetwork design model for intermodal transport: the case of the hinterland of the Port of Cotonou
Lihoussou, Messan ULg; Limbourg, Sabine ULg

in ILS 2012 Proceeding (2012, August 27)

Since 2006, the Millennium Challenge Account program subsidizes a project to improve the performance of the Port of Cotonou, through modernization of infrastructure and management systems, and ... [more ▼]

Since 2006, the Millennium Challenge Account program subsidizes a project to improve the performance of the Port of Cotonou, through modernization of infrastructure and management systems, and strengthening institutional reforms. But the project mainly concerns the port, not the development of its hinterland. However, no port can develop without its links with its hinterland. That’s why we analyse the issues relating to the hinterland transport network. Both rail and road transportation networks will be examined. We also investigate inland terminals in order to build up intermodal transportation which is almost non-operational. Thus, the objective of this paper is to determine the optimal number and locations of the terminals so that the total costs of the distribution network are minimized. [less ▲]

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See detailNetwork Distance Prediction Based on Decentralized Matrix Factorization
Liao, Yongjun ULg; Geurts, Pierre ULg; Leduc, Guy ULg

in Lecture Notes in Computer Science (2010, May 11), 6091

Network Coordinate Systems (NCS) are promising techniques to predict unknown network distances from a limited number of measurements. Most NCS algorithms are based on metric space embedding and suffer ... [more ▼]

Network Coordinate Systems (NCS) are promising techniques to predict unknown network distances from a limited number of measurements. Most NCS algorithms are based on metric space embedding and suffer from the inability to represent distance asymmetries and Triangle Inequality Violations (TIVs). To overcome these drawbacks, we formulate the problem of network distance prediction as guessing the missing elements of a distance matrix and solve it by matrix factorization. A distinct feature of our approach, called Decentralized Matrix Factorization (DMF), is that it is fully decentralized. The factorization of the incomplete distance matrix is collaboratively and iteratively done at all nodes with each node retrieving only a small number of distance measurements. There are no special nodes such as landmarks nor a central node where the distance measurements are collected and stored. We compare DMF with two popular NCS algorithms: Vivaldi and IDES. The former is based on metric space embedding, while the latter is also based on matrix factorization but uses landmarks. Experimental results show thatDMF achieves competitive accuracy with the double advantage of having no landmarks and of being able to represent distance asymmetries and TIVs. [less ▲]

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See detailNetwork Fingerprinting: TTL-Based Router Signatures
Vanaubel, Yves ULg; Pansiot, Jean-Jacques; Mérindol, Pascal et al

in ACM/USENIX Internet Measurement Conference (2013, October)

Fingerprinting networking equipment has many potential applications and benefits in network management and security. More generally, it is useful for the understanding of network structures and their ... [more ▼]

Fingerprinting networking equipment has many potential applications and benefits in network management and security. More generally, it is useful for the understanding of network structures and their behaviors. In this paper, we describe a simple fingerprinting mechanism based on the initial TTL values used by routers to reply to various probing messages. We show that main classes obtained using this simple mechanism are meaningful to distinguish routers platforms. Besides, it comes at a very low additional cost compared to standard active topology discovery measurements. As a proof of concept, we apply our method to gain more insight on the behavior of MPLS routers and to, thus, more accurately quantify their visible/invisible deployment. [less ▲]

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See detailA network for agricultural information technology : systems available in Belgium
Claustriaux, Jean-Jacques ULg

in Houseman, C. I. (Ed.) Agriculture - The establishment of a network for agricultural information technology (1990)

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See detailA network meta-analysis of everolimus plus exemestane versus chemotherapy in the first- and second-line treatment of estrogen receptor-positive metastatic breast cancer.
Generali, Daniele; Venturini, Sergio; Rognoni, Carla et al

in Breast cancer research and treatment (2015), 152(1), 95-117

The goal of this study was to compare the efficacy and toxicity of chemotherapy to exemestane plus everolimus (EXE/EVE) through a network meta-analysis (NMA) of randomized controlled trials. NMA methods ... [more ▼]

The goal of this study was to compare the efficacy and toxicity of chemotherapy to exemestane plus everolimus (EXE/EVE) through a network meta-analysis (NMA) of randomized controlled trials. NMA methods extend standard pairwise meta-analysis to allow simultaneous comparison of multiple treatments while maintaining randomization of individual studies. The method enables "direct" evidence (i.e., evidence from studies directly comparing two interventions) and "indirect" evidence (i.e., evidence from studies that do not compare the two interventions directly) to be pooled under the assumption of evidence consistency. We used NMA to evaluate progression-free survival (PFS) and time to progression (TTP) curves in 34 studies, and response rate (RR) and the hazard ratios (HRs) of the PFS/TTP in 36 studies. A number needed to treat (NNT) analysis was also performed as well as descriptive comparison of reported toxicities. The NMA for PFS/TTP curves and for HR shows EXE/EVE is more efficacious than capecitabine plus sunitinib, CMF, megestrol acetate and tamoxifen, with an average of related-PFS/TTP difference ranging from about 10 months for capecitabine plus sunitinib to more than 6 months for tamoxifen. The NMA for overall RR shows that EXE/EVE provides a better RR than bevacizumab plus capecitabine, capecitabine, capecitabine plus sorafenib, capecitabine plus sunitinib, CMF, gemcitabine plus epirubicin plus paclitaxel, EVE plus tamoxifen, EXE, FEC, megestrol acetate, mitoxantrone, and tamoxifen. Finally, the NMA for NNT shows that EXE/EVE is more beneficial as compared to BMF, capecitabine, capecitabine plus sunitinib, CMF, FEC, megestrol acetate, mitoxantrone, and tamoxifen. The combination of EXE/EVE as first- or second-line therapy for ER+ve/HER2-ve metastatic breast cancer is more efficacious than several chemotherapy regimens that were reported in the literature. Toxicities also favored EXE/EVE in most instances. [less ▲]

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See detailNetwork optimization-based reactive power margin calculation
Van Cutsem, Thierry ULg

in Proc. IFAC Symp. on Power Systems, Modelling and Control Applications (1988)

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See detailNetwork organisation : the impact of dominant paradigms ?
Absil, Gaëtan ULg; Demarteau, Michel

in Archives of Public Health (2009), 67(Supplement 2), 66-67

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See detailNetwork parameter estimation using online data with application to transformer tap position estimation
Van Cutsem, Thierry ULg; Quintana, Victor

in IEE Proceedings - Generation, Transmission & Distribution (1988), 135

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See detailNetwork Virtualization Architecture: Proposal and Initial Prototype
Schaffrath, Gregor; Werle, Christoph; Papadimitriou, Panagiotis et al

in ACM SIGCOMM Workshops Proceedings (2009, August)

The tussle between reliability and functionality of the Internet is firmly biased on the side of reliability. New enabling technologies fail to achieve traction across the majority of ISPs. We believe ... [more ▼]

The tussle between reliability and functionality of the Internet is firmly biased on the side of reliability. New enabling technologies fail to achieve traction across the majority of ISPs. We believe that the greatest challenge is not in finding solutions and improvements to the Internet's many problems, but in how to actually deploy those solutions and re-balance the tussle between reliability and functionality. Network virtualization provides a promising approach to enable the coexistence of innovation and reliability. We describe a network virtualization architecture as a technology for enabling Internet innovation. This architecture is motivated from both business and technical perspectives and comprises four main players. In order to gain insight about its viability, we also evaluate some of its components based on experimental results from a prototype implementation. [less ▲]

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See detailNetwork financing with two-part and single tariffs
Gautier, Axel ULg

in Dewenter, R.; Haucap, J. (Eds.) Access Pricing: Theory and Practice (2007)

In this paper, we compare two types of access pricing: a two-part tariff where the fixed part aims to cover (part of) the network’s fixed cost while the variable part covers the network’s usage costs and a ... [more ▼]

In this paper, we compare two types of access pricing: a two-part tariff where the fixed part aims to cover (part of) the network’s fixed cost while the variable part covers the network’s usage costs and a single tariff where both the usage and (part of ) the infrastructure costs are covered by a per-unit access charge. We compare how the regulator trades-off the degree of competition induced by the access charges and the network financing. (JEL: L11, L51). [less ▲]

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See detailNetworking health care practitioners and occupational prevention services for early rehabilitation of low back pain workers
Mairiaux, Philippe ULg; Creytens, Guido; Delaruelle, Dirk et al

in Archives of Public Health (2009, December), 67(2009-Supplément 2), 60-61

Detailed reference viewed: 12 (0 ULg)
See detailNetworking: Employers' Groups
Dalon, Gelica; Pichault, François ULg

in Gazier, Bernard; Bruggeman, Frédéric (Eds.) Restructuring Work and Employment in Europe. Managing Change in an Era of Globalization (2008)

Studies the conditions under which employers groups can be an alternative solution to layoffs

Detailed reference viewed: 51 (10 ULg)