Browsing
     by title


0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

or enter first few letters:   
OK
Full Text
Peer Reviewed
See detailPolymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men
Vanbillemont, G.; Bogaert, V.; De Bacquer, D. et al

in Clinical Endocrinology (2009), 70(2), 303-310

In men there is a large interindividual variation of SHBG levels and consequently of testosterone (T) and E-2 levels. Family and twin studies suggested a strong genetic contribution, besides metabolic and ... [more ▼]

In men there is a large interindividual variation of SHBG levels and consequently of testosterone (T) and E-2 levels. Family and twin studies suggested a strong genetic contribution, besides metabolic and hormonal influences. The aim of this study was to examine the influence of a missense mutation in exon 8 (Asp327Asn) and a (TAAAA)(n)-repeat in the promoter region of the SHBG gene, on SHBG and sex steroid serum concentrations in a population of healthy men. SHBG and hormone levels were measured in 1485 men, contributed by three independent cohort studies and representing three different age groups (young, middle-aged and elderly men). The number of TAAAA-repeats was determined by fragment-analysis; carriers of the Asn(327)-allele were identified using restriction fragment length polymorphism analysis. In the different age groups, carriers of six TAAAA-repeats presented with higher SHBG (young 19%, middle-aged 20% and elderly 26%; P < 0.001) and T (young 9%, middle-aged 22% and elderly 21%; P < 0.05) levels compared to non-carriers. For free T, a modest increase was found for carriers in the middle-aged group, but not for the young and elderly group. E-2 and free E-2 did not differ between carriers and non-carriers in the different age-groups. The Asn(327)-allele was associated with higher mean SHBG (14.20%, P < 0.001) and T levels (7.33%; P = 0.01) in the middle-aged group only. Our findings show that and the (TAAAA)(n)-repeat and the Asp327Asn polymorphism contribute to the genetically determined interindividual variation in total serum T levels in healthy men through variation in SHBG concentrations. [less ▲]

Detailed reference viewed: 15 (4 ULg)
Full Text
Peer Reviewed
See detailPolymorphous light eruption-like lesions on sun-protected injection sites of recombinant IFN-alpha-2b
Nikkels, Arjen ULg; Delwaide, Jean ULg; Letawe, C. et al

in Journal of Dermatological Treatment (1997), 8(4), 285

Detailed reference viewed: 12 (2 ULg)
Full Text
Peer Reviewed
See detailPolymorphus Minutus Affects Antitoxic Responses of Gammarus Roeseli Exposed to Cadmium
Gismondi, Eric ULg; Beisel, Jean-Nicolas; Cossu-Leguille, Carole

in PLoS ONE (2012), 7

Detailed reference viewed: 1 (0 ULg)
Full Text
See detailPolyneuritis equi. Literatuurstudie & retrospectieve studie
Van Galen, Gaby ULg

Master's dissertation (2003)

Detailed reference viewed: 32 (0 ULg)
Full Text
Peer Reviewed
See detailPolynomial approximation of aerodynamic coefficients based on the statistical description of the wind incidence
Denoël, Vincent ULg

in Probabilistic Engineering Mechanics (2009), 24(2), 179-189

In civil engineering applications, the aerodynamic coefficients are usually measured in wind tunnels for several wind incidences. The measurement results need to be linearized in order to perform the ... [more ▼]

In civil engineering applications, the aerodynamic coefficients are usually measured in wind tunnels for several wind incidences. The measurement results need to be linearized in order to perform the design of the structure. This paper justifies the use of different linearization techniques for different assessments as divergence or buffeting analysis. In this latter context, it is proposed to linearize the aerodynamic coefficient by the least-square method, using the probability density function of the wind incidence as a weighting function. First this probability density function is computed for a 2-D wind flow, as a function of the wind intensities and their correlation. Then, the comparison of results from different linearization techniques provides surprising results indicating that what is usually performed should be considered with care. [less ▲]

Detailed reference viewed: 84 (13 ULg)
Full Text
Peer Reviewed
See detailPolynomial regression with censored data based on preliminary nonparametric estimation
Heuchenne, Cédric ULg; Van Keilegom, Ingrid

in Annals of the Institute of Statistical Mathematics (2007), 59(2), 273-297

Consider the polynomial regression model Y = (beta)0 + beta(1) X + center dot center dot center dot beta X-p(p) + sigma (X)epsilon, where sigma(2)(X) = Var(Y vertical bar X) is unknown, and epsilon is ... [more ▼]

Consider the polynomial regression model Y = (beta)0 + beta(1) X + center dot center dot center dot beta X-p(p) + sigma (X)epsilon, where sigma(2)(X) = Var(Y vertical bar X) is unknown, and epsilon is independent of X and has zero mean. Suppose that Y is subject to random right censoring. A new estimation procedure for the parameters beta(0), center dot center dot center dot, beta (p) is proposed, which extends the classical least squares procedure to censored data. The proposed method is inspired by the method of Buckley and James (1979, Biometrika, 66, 429-436), but is, unlike the latter method, a noniterative procedure due to nonparametric preliminary estimation of the conditional regression function. The asymptotic normality of the estimators is established. Simulations are carried out for both methods and they show that the proposed estimators have usually smaller variance and smaller mean squared error than Buckley-James estimators. The two estimation procedures are also applied to a medical and a astronomical data set. [less ▲]

Detailed reference viewed: 52 (15 ULg)
Full Text
Peer Reviewed
See detailPolynomial regression with censored data based on preliminary nonparametric estimation.
Heuchenne, Cédric ULg; Van Keilegom, Ingrid

in Annals of the Institute of Statistical Mathematics (2007), 59

Detailed reference viewed: 54 (26 ULg)
Full Text
Peer Reviewed
See detailPolyolefin matrixes with permanent antibacterial activity : preparation, antibacterial activity, and action mode of the active species
Lenoir, Sandrine ULg; Pagnoulle, Christophe; Galleni, Moreno ULg et al

in Biomacromolecules (2006), 7(8), 2291-2296

Poly[2-(tert-butylamino)ethyl methacrylate] (PTBAEMA) belongs to a novel class of water-insoluble biocides. Dispersion of a poly(ethylene-co-butylene)-b-poly[2-(tert-butylamino)ethyl methacrylate] diblock ... [more ▼]

Poly[2-(tert-butylamino)ethyl methacrylate] (PTBAEMA) belongs to a novel class of water-insoluble biocides. Dispersion of a poly(ethylene-co-butylene)-b-poly[2-(tert-butylamino)ethyl methacrylate] diblock copolymer (PEB-b-PTBAEMA) within low-density polyethylene (LDPE) imparts antimicrobial properties to the polyolefin as assessed by the viable cell counting method against Escherichia coli (E. coli). This diblock copolymer has been synthesized by atom transfer radical polymerization (ATRP) with a poly(ethylene-co-butylene) (PEB) oligomer end-capped by an activated bromide as a macroinitiator for the polymerization of 2-(tert-butylamino)ethyl methacrylate (TBAEMA). Morphological changes of E. coli bacteria in contact with modified LDPE have been observed by transmission and scanning electron microscopy and indicate that the diblock copolymer is bactericide rather than bacteriostatic. Finally, the action mode of the PEB-b-PTBAEMA copolymer more likely relies on the displacement of the Ca2+ and/or Mg2+ ions of the outer membrane of the bacteria, which is disorganized and finally disrupted. [less ▲]

Detailed reference viewed: 50 (7 ULg)
See detailPolyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species
Lenoir, Sandrine; Pagnoulle, Christophe; Galleni, Moreno ULg et al

Poster (2008, May 22)

Detailed reference viewed: 39 (12 ULg)
Full Text
Peer Reviewed
See detailPolyolefin-based composites by polymerization-filling technique
Dubois, Philippe ULg; Alexandre, Michaël ULg; Hindryckx, François et al

in Journal of Macromolecular Science - Reviews in Macromolecular Chemistry and Physics (1998), 38(3), 511-565

Dispersions of inorganic fillers within polymers are commonly designated as polymer-based composites. The properties of these materials are isotropic or anisotropic, depending on the geometry of the ... [more ▼]

Dispersions of inorganic fillers within polymers are commonly designated as polymer-based composites. The properties of these materials are isotropic or anisotropic, depending on the geometry of the filler particles and the effect of the processing conditions on their orientation. Fillers are used to improve some physicomechanical properties of the polymer, the material processability, or decrease the final cost. As a typical example, highly filled composites in which the filler concentration approaches the maximum packing fraction are known for their use in the shaping of ceramic articles. [less ▲]

Detailed reference viewed: 35 (1 ULg)
Full Text
Peer Reviewed
See detailPolyomavirus in Renal Transplantation: A Hot Problem
Bonvoisin, Catherine ULg; Weekers, Laurent ULg; Xhignesse, Patricia ULg et al

in Transplantation (2008), 85(7S), 42-48

Polyomavirus BK has emerged as an important complication after kidney transplantation. Although, BK nephropathy develops in only1%to5%of renal transplant recipients, its prognosis when present is very ... [more ▼]

Polyomavirus BK has emerged as an important complication after kidney transplantation. Although, BK nephropathy develops in only1%to5%of renal transplant recipients, its prognosis when present is very poor. The most accepted risk factor is the level of immunosuppressive treatment, but the serostatus of donor and recipient and the absence of human leukocyte antigen C7 in donor and/or recipient influence the BK virus (BKV) reactivation. The gold standard in diagnosing BKV nephropathy (BKVN) continues to be biopsy with use of immunohistochemistry for large T antigens. Urinary decoy cells and blood BKV DNA polymerase chain reaction are used in the screening, but their positive predictive values are poor. However, their use as predictors of the evolution of BKVN is more valuable. The reduction of immunosuppressive therapy currently represents the first-line treatment for BKVN. Cidofovir and leflunomide can be used when BKVN continues to progress. In the event of graft loss, retransplantation is possible with a low risk of recurrence when the infection is no longer active. [less ▲]

Detailed reference viewed: 55 (6 ULg)
Full Text
See detailPolypeptide inducing HIV-neutralising antibodies
Brasseur, Robert ULg; Charloteaux, Benoît ULg; Chevalier, Michel et al

Patent (2002)

Detailed reference viewed: 12 (0 ULg)
See detailPolypes coliques et acromégalie
Beckers, Albert ULg

in Acromégalie : Les conséquences de l'hypersomatotropisme (2001)

Detailed reference viewed: 8 (1 ULg)
Full Text
Peer Reviewed
See detailPolyphase karst system in Cretaceous chalk and calcarenite of the Belgian-Dutch border
Willems, Luc ULg; Rodet, Joël; Fournier, Matthieu et al

in Zeitschrift für Geomorphologie (2007), 51(3), 361-376

Along the Belgian-Dutch border, underground and surface quarries dug in Cretaceous calcarenite and chalk intersect many karst features as well as deep large nodes of weathered rock. Their observation ... [more ▼]

Along the Belgian-Dutch border, underground and surface quarries dug in Cretaceous calcarenite and chalk intersect many karst features as well as deep large nodes of weathered rock. Their observation allows the reconstruction of the genesis of an original karst system resulting from the merging of initially independent endokarsts and exokarsts. Deep weathering has developed within the Cretaceous formations, creating nodes of weathered chalk and closed cavities. These phenomena are expanded over time and can form interconnected voids. Near the surface, solution pipes are generated under the coarsest deposits of a fluvial terrace capping the Cretaceous formations. These pipes develop vertically and may be related to the progressive lowering of the water table in connection with the incision of the Meuse valley. Some of these phenomena cut up the older endokarsts and organize complex systems of out-flow within the chalk. [less ▲]

Detailed reference viewed: 26 (4 ULg)
Full Text
Peer Reviewed
See detailPolyphased karst systems in sandstones and quartzites of Minas Gerais, Brazil
Willems, Luc ULg; Rodet, Joël; Pouclet, André et al

in Proceeding 14th UIS Congress, Athens-Kalamos, 23-28 august 2005, Abstract Book : 71. (2005)

The state of Minas Gerais (Brazil) exhibits several major karst areas located in sandstone and quartzite terrains, that display a complex suite of underground and surface karstic forms. In the Espinhaço ... [more ▼]

The state of Minas Gerais (Brazil) exhibits several major karst areas located in sandstone and quartzite terrains, that display a complex suite of underground and surface karstic forms. In the Espinhaço Ridge, central Minas Gerais, several caves, up to a few hundred metres long, occur in the surroundings of the town of Diamantina. Some of these caves, such as Salitre, represent swallow-holes and show dome pits. Other horizontal caves are characterized by corrosion forms generated into the phreatic zone. In some places, such as in the Rio Preto area, these phreatic forms have been overprinted by ceiling tubes, suggesting a polyphase karst evolution, prior to the draining of the cave. Relicts of passages, with circular cross section up to a metre in diametre, can be found amidst the residual tower-like surface landforms, which constitute a typical scenery in the landscape. Their dissection is due to a generalised karstification in the area, resulting in closed canyons, megakarrens and kamenitzas. In southern Minas Gerais, close to the Mantiqueira Ridge, the caves of the state park of Ibitipoca can extent 2 km in length. These caves are associated with a very large hanging geological syncline. Several of these caves contain active streams, that flow for hundreds of metres before disappearing in sand-choked passages. Keyhole cross sections characterize steeply descending passages in these caves, indicating a change from slow phreatic flow towards a faster vadose flow responsible for the vertical incision of the passage. Such change is probably related to base level lowering and/or to turn in the direction of the water flow. Several generations of wall-pockets, from a few centimetres to over a metre long, occur into the caves. These features are good indicators of the initial phase of speleogenesis, generating the initial conduits by their coalescence. This mechanism is also responsible for cut-off meanders. The main river in the area, which flows along the syncline axis, cuts through a rock barrier, generating a tunnel-like passage. This cave drains, through resurgences in its walls, part of the water that flows in other caves located in the flank of the syncline. The non-carbonate karst features observed in the state of Minas Gerais demonstrate the complex organisation of polyphase karst systems due to the linkage of underground and surface forms not previously connected. As in carbonate areas, these systems may play an important hydrological role. [less ▲]

Detailed reference viewed: 15 (0 ULg)
Full Text
Peer Reviewed
See detailA polyphasic approach to assess the cyanobacterial diversity of summer samples from Czech reservoirs
Boutte, Christophe; Komarkova, Jarka; Grubisic, Stana ULg et al

in Algological Studies (2005), 117

We used a polyphasic approach combining data from microscopic assessment of fresh biomass and from clone libraries and DGGE fingerprints based on 16S rRNA gene sequences to investigate the cyanobacterial ... [more ▼]

We used a polyphasic approach combining data from microscopic assessment of fresh biomass and from clone libraries and DGGE fingerprints based on 16S rRNA gene sequences to investigate the cyanobacterial diversity of Czech reservoirs during the summer in 2001 and 2002. In total, 15 genera were identified using the microscopic analysis in 38 samples analysed. They were Aphanizomenon, Anabaena, Anabaenopsis, Aphanocapsa, Aphanothece, Pseudanabaena, Planktothrix, Planktolyngbya, Limnothrix, Woronichinia, Snowella, Romeria, Microcystis, Merismopedia, and Coelomoron. We recovered 113 DGGE band sequences from the same samples. In addition, 128 partial 16S rRNA sequences were obtained from two clone libraries of reservoirs Pilská and Orlík. The phylogenetic comparison with the currently available rRNA sequences in databases showed that our sequences belonged to 8 clusters: Woronichinia, Microcystis, Synechococcus, Snowella, Planktothrix, Anabaena/Aphanizomenon, Limnothrix and a plastid related to Chrysochromulina polylepis. The microscopic enumeration and the molecular results were generally congruent concerning the major populations determined in these samples (for 32 samples among 38). Anabaena/Aphanizomenon, Microcystis and Woronichinia were the major genera in the Czech reservoirs during summer, and were present in most of the samples. This study showed some discrepancies between the genera retrieved by the traditional method and the molecular analyses. Differences concerned the presence of minor populations belonging to Aphanothece, Romeria, Merismopedia, Synechococcus, Snowella and Pseudanabena. These differences could be explained by biases specific to each method (competitive amplification, difficulty to obtain sequences from DGGE bands, not precise microscopic observation of the small-sized genera). [less ▲]

Detailed reference viewed: 64 (8 ULg)
Full Text
Peer Reviewed
See detailPolyphasic Identification Of A New Thermotolerant Species Of Lactic Acid Bacteria Isolated From Chicken Faeces
Sow, Nm.; Dubois Dauphin, Robin ULg; Weber, Dominique ULg et al

in African Journal of Biotechnology (2005), 4(5),

Two thermotolerant and desiccation tolerant lactic acid bacteria (TDLAB) were pointed out from twenty isolated strains from soils and dried chicken faeces. Samples were collected in poultry farms in the ... [more ▼]

Two thermotolerant and desiccation tolerant lactic acid bacteria (TDLAB) were pointed out from twenty isolated strains from soils and dried chicken faeces. Samples were collected in poultry farms in the vicinity of Dakar, Senegal (West Africa). The two new isolates were called Sp.4 (Sp.4=CWBI-B534=LMG7278) and Sp.20 (Sp.20=CWBI-B545=LMG7279). They are Grampositive, catalase-negative, facultatively anaerobic, non-motile, and non-spore-forming rods. Both produce D/L lactic acid via homofermentative pathway. Growth of the strains occurred between 15°C and 44°C. The optimum temperature for growth was in 30°C-37°C temperature and pH 3-8 range. Desiccation treatment in glycerol showed 30% survival rates. Complex total fatty acid pattern of the strains showed the presence of C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, C18:3. SDS-PAGE of total protein of both strains placed them in L. plantarum group. AFLP analysis showed a phylogenetic proximity of the two strains with L. plantarum stricto sensu species. Specific amplified 16s rDNA restriction analysis (ARDRA) of the 16S rDNA gene, however, showed that these thermotolerant strains were not L. plantarum. ITS sequencing revealed that Sp.20 (LMG 7279) could be classed into Lactobacillus paraplantarum species since the short sequence of ITS showed 95% of similarity with reference species. Polyphasic identification shows that Sp.4, (the type strain is LMG 7278T) represent a new species within the genus Lactobacillus with only 88%+/-1 ITS sequence similarity with reference species. For which the name Lactobacillus aminata sp. nov. is proposed. [less ▲]

Detailed reference viewed: 63 (1 ULg)
Full Text
Peer Reviewed
See detailPolyphasic study of Antarctic cyanobacterial strains
Taton, A.; Grubisic, Stana ULg; Ertz, D. et al

in Journal of Phycology (2006), 42(6), 1257-1270

We isolated 59 strains of cyanobacteria from the benthic microbial mats of 23 Antarctic lakes, from five locations in two regions, in order to characterize their morphological and genotypic diversity. On ... [more ▼]

We isolated 59 strains of cyanobacteria from the benthic microbial mats of 23 Antarctic lakes, from five locations in two regions, in order to characterize their morphological and genotypic diversity. On the basis of their morphology, the cyanobacteria were assigned to 12 species that included four Antarctic endemic taxa. Sequences of the ribosomal RNA gene were determined for 56 strains. In general, the strains closely related at the 16S rRNA gene level belonged to the same morphospecies. Nevertheless, divergences were observed concerning the diversity in terms of species richness, novelty, and geographical distribution. For the 56 strains, 21 operational taxonomic units (OTUs, defined as groups of partial 16S rRNA gene sequences with more than 97.5% similarity) were found, including nine novel and three exclusively Antarctic OTUs. Sequences of Petalonema cf. involvens and Chondrocystis sp. were determined for the first time. The internally transcribed spacer (ITS) between the 16S and the 23S rRNA genes was sequenced for 33 strains, and similar groupings were observed with the 16S rRNA gene and the ITS, even when the strains were derived from different lakes and regions. In addition, 48 strains were screened for antimicrobial and cytotoxic activities, and 17 strains were bioactive against the gram-positive Staphylococcus aureus, or the fungi Aspergillus fumigatus and Cryptococcus neoformans. The bioactivities were not in coincidence with the phylogenetic relationships, but rather were specific to certain strains. [less ▲]

Detailed reference viewed: 60 (7 ULg)
Full Text
Peer Reviewed
See detailPolyphenol Content and Modulatory Activities of Some Tropical Dietary Plant Extracts on the Oxidant Activities of Neutrophils and Myeloperoxidase
Tsumbu, César Ndele ULg; Deby-Dupont, Ginette; Tits, Monique ULg et al

in International Journal of Molecular Sciences (2012), 13(1), 628-650

Detailed reference viewed: 76 (22 ULg)
Full Text
Peer Reviewed
See detailPOLYPHENOL VARIABILITY IN THE FRUITS AND JUICES OF A CIDER APPLE PROGENY
Verdu, Cindy ULg; Childebrand, Nicolas; Marnet, Nathalie et al

in Journal of the Science of Food and Agriculture (2013)

BACKGROUND: Polyphenols have a favorable antioxidant potential on human health, suggesting that their high content in apple is responsible for the beneficial effects of apple consumption. They are also ... [more ▼]

BACKGROUND: Polyphenols have a favorable antioxidant potential on human health, suggesting that their high content in apple is responsible for the beneficial effects of apple consumption. They are also linked to the quality of apple juices and ciders since they are predominantly responsible for astringency, bitterness, color and aroma. Major phenolic compounds were quantified by liquid chromatography in fruits and juices from a cider apple progeny harvested for three years. The total content of procyanidins and their average degree of polymerization (DPn) were also determined in fruits by phloroglucinolysis. Variability and extraction yield of these compounds were determined. RESULTS: The variability observed in the progeny was representative of the variability observed in many cider apple varieties. Hydroxycinnamic acids were the most extractable group, with an average extraction yield of 67%, whereas flavonols and anthocyanins were the least. CONCLUSION: This study is the first one to introduce variability and extraction yields of the main phenolic compounds in both fruits and juices of a cider apple progeny. This dataset will be used for an upcoming QTL mapping study, an original approach that has never been undertaken for cider apple. [less ▲]

Detailed reference viewed: 26 (7 ULg)