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See detailOPTIMIZATION OF A NEW TWO-PLATE SCREENING METHOD FOR THE DETECTION OF ANTIBIOTIC RESIDUES IN MEAT.
Pham Kim, Dang; Degand, Guy ULg; Danyi, Sophie et al

Poster (2011)

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See detailOptimization of a PGSS (particles from gas saturated solutions) process for a fenofibrate lipid-based solid dispersion formulation
Pestieau, Aude ULg; Krier, Fabrice ULg; Lebrun, Pierre ULg et al

in International Journal of Pharmaceutics (2015), 485

The aim of this study was to develop a formulation containing fenofibrate and Gelucire® 50/13 (Gattefossé, France) in order to improve the oral bioavailability of the drug. Particles from Gas Saturated ... [more ▼]

The aim of this study was to develop a formulation containing fenofibrate and Gelucire® 50/13 (Gattefossé, France) in order to improve the oral bioavailability of the drug. Particles from Gas Saturated Solutions (PGSS) process was chosen for investigation as a manufacturing process for producing a solid dispersion. The PGSS process was optimized according to the in vitro drug dissolution profile obtained using a biphasic dissolution test. Using a design of experiments approach, the effects of nine experimental parameters were investigated using a PGSS apparatus provided by Separex® (Champigneulles, France). Within the chosen experimental conditions, the screening results showed that the drug loading level, the autoclave temperature and pressure, the connection temperature and the nozzle diameter had a significant influence on the dissolution profile of fenofibrate. During the optimization step, the three most relevant parameters were optimized using a central composite design, while other factors remained fixed. In this way, we were able to identify the optimal production conditions that would deliver the highest level of fenofibrate in the organic phase at the end of the dissolution test. The closeness between the measured and the predicted optimal dissolution profiles in the organic phase demonstrated the validity of the statistical analyses. [less ▲]

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See detailOptimization of a reliable, fast, cheap and sensitive silver staining method to detect SSR markers in polyacrylamide gels.
Benbouza, H.; Jacquemin, J. M.; Baudoin, Jean-Pierre ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2006), 10(2), 77-81

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See detailOptimization of a Rolling and Floating Lock Gate for the Port of Antwerp
Richir, Thomas; Pecket, J.-P.; Toderan, C. et al

in ICCC-ASCE: 2006, Int'l Conf. on Computing in Civil Engineering of ASCE, Joint International Conference on Computing and Decision Making in Civil and Building Engineering, Montreal, Canada, June 2006, Paper IC-23, pp155-163 (2006, June)

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See detailOptimization of a scroll compressor for liquid flooding
Bell, Ian ULg; Groll, Eckhard; Braun, James et al

in International Journal of Refrigeration (2012), 35(7), 19011913

In two companion papers, simulation models for the working processes of liquid-flooded scroll compressors and expanders have been developed and validated against experimental data. In this study, analytic ... [more ▼]

In two companion papers, simulation models for the working processes of liquid-flooded scroll compressors and expanders have been developed and validated against experimental data. In this study, analytic models are presented for the modes of irreversibility generation in the liquid-flooded scroll compressor including built-in volume ratio maladjustment, pressure drop and leakage. A thermodynamic model is used to derive the ideal volume ratio for a liquid-flooded compressor, which is higher than that of dry compression. An optimum set of built-in volume ratio and scroll base circle radius is found which maximizes the overall isentropic efficiency by minimizing the leakage and pressure drop irreversibilities. The irreversibility generation models are used to optimize a scroll compressor for the Liquid-Flooded Ericsson cycle application. The model predicts scroll compressor overall isentropic efficiency of over 80% (based on the shaft power) at an oil mass fraction of 88%. [less ▲]

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See detailOptimization of a triple antibiotic paste. Evaluation of its antibacterial In Vitro Effect and its release Porfile.
Chavarria Bolanos, Daniel ULg; Cerda Cristerna, Bernardino; Pozos-Guillen, Amaury et al

Poster (2013, November 28)

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See detailOptimization of an Haematococcus pluvialis medium by a Genetic Algorithm-based strategy
Fratamico, Anthony ULg; Tocquin, Pierre ULg; Franck, Fabrice ULg

Poster (2012, June 14)

The successful use of living organisms for the production of biomass or metabolites requires a careful control and optimization over growing conditions. However the range of interacting parameters makes ... [more ▼]

The successful use of living organisms for the production of biomass or metabolites requires a careful control and optimization over growing conditions. However the range of interacting parameters makes full optimization difficult and time-consuming. In this context, Genetic Algorithm-based (GA) methods emerge as promising strategies for optimization of biotechnological processes. However, the potential of GA in the microalgae field remains, today, poorly explored. As a proof-of-concept, we evaluated how GA could be applied for the optimization of a medium for high yield photoautotrophic growth of Haematoccocus pluvialis. [less ▲]

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See detailOptimization of BaZrO3 sintering by control of the initial powder size distribution; a factorial design statistical analysis
Guillaume, Bernard ULg; Boschini, Frédéric ULg; Garcia-Cano, I. et al

in Journal of the European Ceramic Society (2005), 25(16), 3593-3604

A factorial design statistical analysis has been conducted in order to obtain the optimum conditions in the solid state sintering process of barium zirconate bulk materials, optimum with respect to ... [more ▼]

A factorial design statistical analysis has been conducted in order to obtain the optimum conditions in the solid state sintering process of barium zirconate bulk materials, optimum with respect to density, closed and open porosities. The optimized heat treatment permits to sinter a 99% dense barium zirconate sample at 1650 degrees C during only 2 h. When the temperature is higher than 1650 degrees C or when the heating time is longer than 2 h, a decrease in density is observed. (c) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 35 (1 ULg)
See detailOptimization of bioconversion of vanillin into vanillic acid by Pseudomonas fluorescens strain BTP9
Bare, G.; Delaunois, V.; Perrin, L. et al

Poster (1993, July)

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See detailOptimization of biodegradable microparticles for tissue engineering
Drozdova, M.; Demina, T.; Sevrin, Chantal ULg et al

Poster (2013, June 19)

Detailed reference viewed: 11 (1 ULg)