Squatting test: a dynamic postural manoeuvre to study baroreflex sensitivity.SCHEEN, André ; PHILIPS, Jean-Christophe ![]() in Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2011) INTRODUCTION: Squatting is an active posture test that can be used to assess baroreflex sensitivity. Indeed, the shift from squatting to standing imposes a major orthostatic stress leading to rapid and ... [more ▼] INTRODUCTION: Squatting is an active posture test that can be used to assess baroreflex sensitivity. Indeed, the shift from squatting to standing imposes a major orthostatic stress leading to rapid and large changes in arterial blood pressure (BP) and heart rate (HR) allowing precise baroreflex assessment. MATERIAL AND METHODS: BP and HR can be continuously and non-invasively monitored with a Finapres device. RESULTS: The standing to squatting transition is accompanied by rises in BP, pulse pressure and cardiac output, mainly due to increased venous return, and by a secondary reduction in HR. Conversely, the squatting to standing transition is associated with an immediate drop in BP and both reflex tachycardia and vasoconstriction. This mirror changes in BP and HR, mimicking those observed with the classical pharmacological approach using vasopressor/vasodilating agents, allows the calculation of the so-called baroreflex gain. DISCUSSION: The present review describes the haemodynamic changes occurring in normal subjects during the shifts from standing to squatting and from squatting to standing and discusses the underlying cardiovascular and autonomic mechanisms. CONCLUSION: This careful analysis in healthy individuals should help in the understanding of disturbances that may be observed in patients with autonomic dysfunction, such as in diabetic patients with cardiovascular autonomic neuropathy. [less ▲] Detailed reference viewed: 8 (0 ULg) Squatting test: A posture to study and counteract cardiovascular abnormalities associated with autonomic dysfunction.PHILIPS, Jean-Christophe ; SCHEEN, André ![]() in Autonomic neuroscience : basic & clinical (2011) The squatting test is an active posture manoeuvre that imposes one of the most potent orthostatic stresses. In normal subjects, the changes in blood pressure and heart rate are transient because of ... [more ▼] The squatting test is an active posture manoeuvre that imposes one of the most potent orthostatic stresses. In normal subjects, the changes in blood pressure and heart rate are transient because of appropriate baroreflex homeostasis and do not provoke symptoms. However, in various pathological conditions, both the increase in blood pressure during squatting and the decrease in blood pressure during standing may be more important and sustained, potentially leading to complaints and adverse events. Squatting has been used to evaluate patients with tetralogy of Fallot, heart transplant, dysautonomia, including diabetic cardiovascular autonomic neuropathy, and individuals prone to vasovagal syncope. Careful analysis of changes in blood pressure and heart rate during the transition from standing to squatting and from squatting to standing allows the early detection of altered vagal and/or sympathetic function. Of note squatting position has been proposed as a therapeutic means to counteract the fall in blood pressure in patients suffering from dizziness due to dysautonomia and orthostatic hypotension or presenting pre-syncope symptoms, such as soon after exercise. The aims of the present review are to analyse the haemodynamic pattern during a squatting test in various pathological situations and to describe what may be the negative and positive haemodynamic changes associated with this posture. We were especially interested in using the squatting test for the assessment of cardiovascular autonomic neuropathy associated with diabetes mellitus. [less ▲] Detailed reference viewed: 14 (1 ULg) Squatting to standing: an unusual but powerful postural manoeuvre to investigate human arterial blood pressure regulation; ; et al in Archives of Physiology & Biochemistry (1992), 100(5), 31-51 Detailed reference viewed: 15 (3 ULg) Squatting, a posture test for studying cardiovascular autonomic neuropathy in diabetes.PHILIPS, Jean-Christophe ; MARCHAND, Monique ; SCHEEN, André ![]() in Diabètes & Métabolism (2011), 37(6), 489-496 Cardiovascular autonomic neuropathy (CAN) is a frequent complication of diabetes mellitus, which is associated with increased morbidity and mortality. It involves both the parasympathetic and sympathetic ... [more ▼] Cardiovascular autonomic neuropathy (CAN) is a frequent complication of diabetes mellitus, which is associated with increased morbidity and mortality. It involves both the parasympathetic and sympathetic nervous systems, and may be diagnosed by classical dynamic tests with measurements of heart rate (HR) and/or arterial blood pressure (BP). An original squat test (1-min standing, 1-min squatting, 1-min standing) was used with continuous monitoring of HR and BP, using a Finapres((R)) device. This active test imposes greater postural stress than the passive head-up tilt test, and provokes large changes in BP and HR that can be analyzed to derive indices of CAN. In healthy subjects, squatting is associated with BP increases and HR decreases (abolished by atropine: SqTv index), whereas the squat-stand transition is accompanied by a deep but transient drop in BP associated with sympathetic-driven tachycardia (abolished by propranolol: SqTs index). In diabetic patients with CAN, BP increases are accentuated during squatting whereas reflex bradycardia is reduced. When standing from squatting position, the fall in BP tends to be more pronounced and orthostatic hypotension more prolonged, while reflex tachycardia is markedly dampened. The baroreflex gain, similar to that calculated during pharmacological testing with vasodilator/vasopressor agents, can be derived by plotting pulse intervals (R-R) against systolic BP levels during the biphasic response following the squat-stand transition. The slope, which represents baroreflex sensitivity, is significantly reduced in patients with CAN. This discriminatory index allows study of the natural history of CAN in a large cohort of diabetic patients. [less ▲] Detailed reference viewed: 11 (0 ULg) Sr, Nd isotopes and geochemistry of the Bayuda Desert high-grade metamorphic basement (Sudan): An early Pan-African oceanic convergent margin, not the edge of the East Saharan ghost craton?; Liégeois, Jean-Paul ![]() in Precambrian Research (2001), 109(1-2), 1-23 The high-grade metamorphic basement of the Bayuda Desert is situated at the inferred transition between the juvenile Neoproterozoic mainly greenschist facies Arabian-Nubian Shield (ANS) and the pre ... [more ▼] The high-grade metamorphic basement of the Bayuda Desert is situated at the inferred transition between the juvenile Neoproterozoic mainly greenschist facies Arabian-Nubian Shield (ANS) and the pre-Neoproterozoic mainly amphibolite facies domain of the East Saharan Ghost Craton. New geochemical and Sr-Nd isotope data reveal that this basement in Bayuda constituted a Neoproterozoic oceanic convergent margin succession with limited and probably late input of old material. Within this series, garnet amphibolites and epidote-biotite gneisses have geochemical characteristics of HFSE-depleted tholeiitic basalts and low- to medium-K dacites and rhyodacites, indicating magmatism in an oceanic island arc or back-arc basin environment. This magmatism occurred at 806 ± 19 Ma (Sm-Nd 11 WR isochron), similar in age to arc magmatism in the ANS. Leucocratic gneisses, muscovite schists and garnet-biotite schists form the dominant meta-sedimentary rocks of the study area. They were primarily derived from two different sources: volcanogenic sediments from a Neoproterozoic island arc (TDM Nd model ages between 790 and 900 Ma) and terrigeneous sediments from an older continental source (TDM Nd model ages up to 2100 Ma). The volcanosedimentary succession was metamorphosed under amphibolite facies conditions prior to 670 Ma, probably at approximately 700 Ma. The high-grade metamorphism is related to a frontal collisional event that also produced syn-collisional peraluminous granites preserved as muscovite-biotite gneisses. Meta-igneous rocks from eastern Bayuda have εNd values at 806 Ma of + 5.2 ± 0.4, indicating a less depleted mantle source (crustal contamination can be excluded) than the neighbouring Gabgaba-Gebeit terrane (εNd, ca. + 7) from the Arabian-Nubian shield. Less depleted mantle source is also known at Jebel Moya to the south, and inside the Arabian-Nubian Shield to the southeast of Bayuda. Lithological and structural similarities (dominantly northeast striking foliation) with the Bayuda Desert succession occur in many parts of central and western Sudan, suggesting a comparable geodynamic evolution. It is proposed that a Neoproterozoic oceanic convergent margin (Bayuda type succession) collided at approximately 700 Ma to the northwest with the East Saharan ghost craton, whose easternmost limit must lie below or more to the west than previously thought. © 2000 Elsevier Science B.V. [less ▲] Detailed reference viewed: 7 (0 ULg) Srength and behaviour of in-plane weak axis joints and of 3-D joints.; Jaspart, Jean-Pierre ; Maquoi, René ![]() in Proceedings of a State-of-the art workshop on connections and the behaviour, strength and design of steel structures. (1988, February) Detailed reference viewed: 23 (0 ULg) SS433, un étrange objet galactiqueManfroid, Jean ![]() Article for general public (1988) Not Available Detailed reference viewed: 6 (0 ULg) SS433, un étrange objet galactique.Manfroid, Jean ![]() Article for general public (1988) The author gives here a brief account of the discovery of SS433, of the theories proposed to explain it and of the mysteries still to be unravelled. Detailed reference viewed: 8 (0 ULg) St Lambert and the Mosan SaintsGeorge, Philippe ![]() in Treasures from Liege - Trésors de Liège, p. 65-82 (1985) Detailed reference viewed: 2 (0 ULg) St-Michel reconstruction project in Liège: A case study of morphological regulationTeller, Jacques ![]() in Dubina, D.; Vayas, I.; Ungureanu, V. (Eds.) Proc. of New technologies and structures in civil engineering. Case studies on Remarkable Constructions (1998) Detailed reference viewed: 12 (1 ULg) The St-Michel reconstruction-project in Liège : A morphological regulation case studyTeller, Jacques ; in Proc. of COST Urban Civil Engineering - Action C4 Final Conference (1998) Detailed reference viewed: 11 (2 ULg) Staal-BetonMaquoi, René ; ; Demonceau, Jean-François et alBook published by Infosteel (2011) Detailed reference viewed: 39 (6 ULg) Staalname van de hersenstam voor TSE-Onderzoek bij het schaap; Gabriel, Annick ; in Vlaams Diergeneeskundig Tijdschrift (2002), 71 La stabilisation aux liants hydrauliques et aériens : une solution adaptée en voiries agricoles et forestièresMarcoen, Jean Marie ; ; et alin Journal des Ingénieurs (1991) Detailed reference viewed: 25 (2 ULg) Stabilisation des sols à la chaux. Action de la chaux vive sur la bentonite et sur la kaolinite.; Marcoen, Jean Marie ; et alin Bulletin des Recherches Agronomiques de Gembloux (1984), 19(1-2), 81-110 Detailed reference viewed: 12 (0 ULg) Stabilisation des sols en place aux liants hydrauliques en voiries agricoles et forestières : Critères d'application; Marcoen, Jean Marie ![]() in Entrepreneur Magazine (1990), 1 Detailed reference viewed: 4 (0 ULg) La stabilisation fonctionnelle lombaire : Défintion du concept et arguments scientifiquesDemoulin, Christophe ; DISTREE, Vincent ; TOMASELLA, Marco et alin Abstract book des Mardis de la Kinésithérapie (2008) Detailed reference viewed: 9 (3 ULg) Stabilisation métabolique par introduction d’atomes de fluor : application aux benzothiadiazine 1,1-dioxydes agissant en tant que potentialisateurs AMPAFrancotte, Pierre ; ; Goffin, Eric et alPoster (2009, May) Detailed reference viewed: 9 (1 ULg) Stabilisation vibratoire de la ligne de galvanisation Eurogal - Etude paramétriqueBruls, Olivier ; ; Golinval, Jean-Claude ![]() Report (2001) Detailed reference viewed: 81 (3 ULg) Stabilité des collyres à base de chlorhydrate de cystéineEvrard, Brigitte ; Delattre, Luc ; in Pharmakon (1987), 69 Detailed reference viewed: 21 (1 ULg) |
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